baber/WOPTO huggingface dataset:
Patent NZ-570563-A (NZ)
Title: Hybrid impact modifiers and method for preparing the same
Inventor: PIRRI ROSANGELA
IPC: C08K9/04
Filed: 2007-02-09
Abstract: Disclosed is a method of preparing hybrid impact modifiers which comprises the steps of: (a) providing (i) a latex or slurry of standard impact modifiers selected from the group consisting of methacrylate-butadiene-styrene copolymers (MBS), acrylonitrile-butadiene-styrene copolymers (ABS), acrylic core/shell polymers (AIM) and CPE (chlorinated polyethylene) and (ii) a slurry of a mineral filler selected from the group consisting of grinded natural calcium carbonate (GCC), precipitated calcium carbonate (PCC), nanosized PCC (NPCC), clay, montmorillonite (nano-clay), zeolite, perlite or any other type of inorganic material that can be obtained as a slurry; (b) introducing (i) and (ii) separately or in combination into a drying unit; and (c) drying the mixture of (i) and (ii) (such as by spray drying, coagulation, freeze coagulation etc.). Further disclosed is an article which comprises a thermoplastic polymer containing a hybrid impact modifier prepared by the above method, wherein said article is a pipe or a profile or a siding.
Patent NZ-576336-A (NZ)
Title: USE OF ESTRADIOL VALERATE OR 17-beta-ESTRADIOL IN COMBINATION WITH DIENOGEST FOR ORAL THERAPY FOR MAINTAINING AND/OR INCREASING THE FEMALE LIBIDO
Inventor: ZEUN SUSAN
IPC: A61P15/00
Filed: 2007-10-12
Abstract: Disclosed is the use of estradiol valerate or 17-beta-estradiol in combination with 17-alpha-cyanomethyl-17-beta-hydroxyestra-4,9-dien-3-one (dienogest), for producing a multiphase combination product or a single-phase combination product for oral therapy for treating decreased female libido.
Patent NZ-580944-A (NZ)
Title: Reversible baseboard for covering a flooring border with end connecting piece
Inventor: SONDERMANN FRANK
IPC: E04F19/04
Filed: 2009-11-04
Abstract: The baseboard has a side with a first contour and an opposite side with a second contour. In order to be able to mount the baseboard in either of two 180O-rotated positions the baseboard has a longitudinally extending axis of symmetry. The first contour in a first end region, rotated 180O about the axis of symmetry corresponds to the second contour in a second end region, and vice versa. An end connecting piece is used to clamp the baseboard and cover the ends.
Patent NZ-584633-A (NZ)
Title: Human antibodies that bind mesothelin, and uses thereof
Inventor: TERRETT JONATHAN A
IPC: C12P21/08
Filed: 2008-09-29
Abstract: An isolated human monoclonal antibody that binds human mesothelin. The antibody has at least one of the following properties: (a) binds to human mesothelin with a KD of 1 x 10-8 or less; (b) is internalized by mesothelin-expressing cells; (c) inhibits binding of mesothelin to ovarian cancer antigen CA125; (d) exhibits antibody dependent cellular cytotoxicity (ADDC) against mesothelin-expressing cells; or (e) inhibits growth of mesothelin-expressing cell in vivo when conjugated to a cytotoxin. The antibody comprises the H-CDRs defined by SEQ ID NOs: 2, 5 and 8, and the L-CDRs defined by SEQ ID NOs: 11, 14 and 17. The heavy chain variable region can comprise SEQ ID NO: 20 and the light chain variable region can comprise SEQ ID NO: 23. The antibody can further be conjugated through a chemical linker to a therapeutic cancer drug. In particular the drug is the cytotoxin duromycin. The antibody or antibody-drug conjugate can be used to treat cancer.
Patent NZ-587743-A (NZ)
Title: Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists
Inventor: VAN LOEVEZIJN ARNOLD
IPC: A61K31/4155
Filed: 2009-03-17
Abstract: Disclosed are arylsulfonyl pyrazoline carboxamide derivatives of formula (1), stereoisomers, N-oxides, and salts thereof, and methods of their preparation. The arylsulfonyl moiety bears an H-bond donor functionality and the compounds are 5-HT6 receptor antagonists. Specific compounds of formula (1) include: 4-Amino-N-[(2,3-diaza-spiro[4.4]non-3-en-2-yl)-ethylamino-methylene]benzenesulfonamide, 4-Amino-N-[(2,3-diaza-spiro[4.4]non-3-en-2-yl)-ethylamino-methylene]-3-fluoro-benzenesulfonamide, and 4-Amino-3-chloro-N-[(4,4-dimethyl-4,5-dihydro-pyrazol-1-yl)-ethylamino-methylene]-benzenesulfonamide Compounds of formula (1) are useful for treating Parkinson's disease, Huntington's chorea, schizophrenia, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders, migraine, Alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, binge eating disorders, panic attacks, akathisia, attention deficit hyperactivity disorder, attention deficit disorder, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, disorders associated with spinal trauma or head injury, hydrocephalus, functional bowel disorder, Irritable Bowel Syndrome, obesity and type-2 diabetes.
Patent NZ-589372-A (NZ)
Title: Fatty acid derivatives for oral administration endowed with high palatability
Inventor: CORUZZO ANNA
IPC: A61K31/165
Filed: 2009-04-21
Abstract: 589372 Disclosed are N-(1-carbamoyl-2-phenyl-ethyl)butyramide derivatives selected from N-(1-carbamoyl-2-phenyl-ethyl)butyramide; N-(1-butyroyl-carbamoyl-2-phenyl-ethyl)butyramide; 5-benzyl-2-propyl-1H-imidazol-4(5H)-one; N-(1-oxo-3-phenyl-1-(piperidin-1-yl)propan-2-yl)butyramide; N-(1-oxo-3-phenyl-1-(pyrrolidin-1-yl)propan-2-yl)butyramide; N-(1-(methylcarbamoyl)-2-phenylethyl)butyramide; N-(1-(ethylcarbamoyl)-2-phenylethyl)butyramide; N-(1-(propylcarbamoyl)-2-phenylethyl)butyramide; N-(1-(butylcarbamoyl)-2-phenylethyl)butyramide; N-(1-(pentylcarbamoyl)-2-phenylethyl)butyramide; N-(1-carbamoyl-2-phenylethyl)-N-methylbutyramide; N-(1-carbamoyl-2-phenylethyl)-N-ethylbutyramide; and N-(1-carbamoyl-2-phenylethyl)-N-propylbutyramide; and corresponding mixtures and salts of pharmaceutically acceptable bases or acids, pure diastereoisomeric forms and enantiomeric forms or mixtures thereof. Also disclosed is a process for the preparation of the above compounds and their mixtures comprising the stages of reacting a phenylalanine derivative and a butyroyl derivative, in substantially equimolecular amounts, in an aprotic polar or inert organic solvent at room temperature, separating, and purifying the product obtained. Further disclosed is the use of one or more compounds having the general formula (I) wherein: A represents a straight or branched alkyl chain, possibly substituted with phenyl; X represents nitrogen; R and R1 independently represent hydrogen or an alkyl group or a acyl group and W is nil; or W represents a 1,2-alkylene chain with 2 to 6 carbon atoms and R and R1 are methylene groups; R2 represents hydrogen or an alkyl group or an acyl group; R3 is selected from the group consisting of H, alkyl, alkoxyl, halogen, oxidryl, cyano, nitro, amino, mono- or di-alkylamino, acylamino, formyl, hydroxyiminomethyl, alkoxyiminomethyl and carbamoyl; corresponding salts with pharmaceutically acceptable bases or acids thereof, pure diastereoisomeric forms and enantiomeric forms or mixtures thereof; for preparing a pharmaceutical preparation endowed with palatability.
Patent NZ-592178-A (NZ)
Title: Preparation of fuels and other useful organic chemical products from algal biomass utilising a phosphate catalyst
Inventor: MILLER IAN JAMES
IPC: C12P13/02
Filed: 2009-09-11
Abstract: 592178 Disclosed is a method for producing fuels and other useful organic chemical products from algal biomass comprising: (i) heating an aqueous slurry comprising algal biomass and water in a pressure vessel at a temperature of about 150 DEGREE C to about 500 DEGREE C in the presence of a phosphate catalyst (such as trisodium phosphate, sodium phosphate, disodium hydrogen phosphate, sodium dihydrogen phosphate, ammonium dihydrogen phosphate, ammonium hydrogen phosphate, calcium phosphate, magnesium ammonium phosphate, ferric phosphate, aluminium phosphate, etc.) to produce a mixture comprising a dispersion of an organic phase and an aqueous phase; and (ii) optionally separating one or more organic chemical products from the mixture.
Patent NZ-595502-A (NZ)
Title: Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
Inventor: GRAY KEVIN A
IPC: A23L11/20
Filed: 2006-12-08
Abstract: NZ 595502 Disclosed is an enzyme ensemble, or "cocktail", for depolymerisation of cellulosic and hemicellulosic polymers to metaboliseable carbon moieties comprising a mixture of enzymes, at least one of which is an isolated, synthetic or recombinant amino acid sequence having at least 75% or more sequence identity to SEQ ID NO: 522, as defined in the complete specification. The disclosed amino acid polypeptide in the enzyme ensemble has beta-glucosidase activity.
Patent NZ-597419-A (NZ)
Title: Formulations for the treatment of deep tissue pain
Inventor: ILIFFE GEORGE LANGTON
IPC: A61K9/127
Filed: 2010-06-03
Abstract: 597419 Disclosed herein are vesicular formulations comprising one or more phospholipids and one or more nonionic surfactants that are effective in the treatment of pain or inflammation or osteoarthritis, more specifically in the treatment of deep tissue pain, for example osteoarthritis and other joint or muscle pain, as well as methods of treating pain or inflammation or osteoarthritis, more specifically in the treatment of deep tissue pain, for example osteoarthritis and other joint or muscle pain using same.
Patent NZ-597503-A (NZ)
Title: Microbiocidal heterocycles
Inventor: QUARANTA LAURA
IPC: C07D231/12
Filed: 2010-08-06
Abstract: IP No. 597503 The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)-C(=O)-, x-C(R12R13)-C(=S)-, x-O-C(=O)-, x-O-C(=S)-, x-N(R14)-C(=O)-, x-N(R15)-C(=S)-,x-C(R16R17)-SO2- or X-N=C(R30)-,, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is phenyl, pyridyl, imidazolyl, or pyrazolyl; wherein the phenyl, pyridyl, imidazolyl and pyrazolyl are each optionally substituted by 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18,R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a): wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
Patent NZ-598054-A (NZ)
Title: Bicycle frame with a bottom bracket to support a crank assembly
Inventor: D ALUISIO CHRISTOPHER P
IPC: B62K3/02
Filed: 2012-02-07
Abstract: 598054 Disclosed is a bicycle frame configured to support a front wheel and a rear wheel defining a central plane (35). The bicycle frame has a head tube; a bottom bracket configured to support a crank assembly; and a seat stay including a leading edge (170) and a trailing edge (175) oriented such that a chord line between the leading edge and the trailing edge defines an angle of incidence greater than zero degrees relative to the central plane.
Patent NZ-598709-A (NZ)
Title: Treating acute decompensated heart failure with relaxin
Inventor: WHITEHOUSE MARTHA JO
IPC: A61K38/22
Filed: 2009-05-15
Abstract: Disclosed is the use of H2 relaxin to treat acute heart failure and related symptoms in a variety of patient groups.
Patent NZ-601898-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: A23L33/00
Filed: 2009-04-28
Abstract: This invention relates to processing biomass particularly cellulose, hemicellulose or starch, with electron beam irradiation of not greater than 10 Mrad, followed by treatment with an enzyme and/or microorganism to produce a edible material. The enzyme may be cellulase, and the biomass may be selected from paper, paper products, paper waste, wood, particle board, sawdust, agricultural waste, sewage, silage, grasses, rice hulls, bagasse, cotton, jute, hemp, flax, bamboo, sisal, abaca, straw, corn cobs, corn stover, switchgrass, alfalfa, hay, coconut hair, seaweed, algae, and mixtures thereof. The edible material is selected from the group consisting of proteins, fats, vitamins, oils, fiber and minerals.
Patent NZ-603687-A (NZ)
Title: Cornice cement applicator
Inventor: LUVARA AARON
IPC: B05C17/005
Filed: 2008-07-18
Abstract: 603687 A cornice cement (102, 104) applicator (100) has a reservoir for holding cornice cement (102, 104) and at least one dispensing nozzle for depositing a bead of cornice cement (102, 104) in a desired location along the cornice (120). As the applicator (100) is passed along the cornice (120), a piston or other actuator causes ejection of cornice cement (102, 104) from the reservoir out the dispensing nozzles (138, 140). Appropriate nozzle design provides for deposition of a bead of cornice having sufficient cement but without surplus, neatly and at a substantially faster rate than can be achieved by manual trowelling. Such an applicator (100) with two dispensing nozzles (138, 140) spaced apart by about the width of the cornice (120) can simultaneously deposit a bead of cement along both rear edges (122, 124) of the cornice (120) in a single pass, saving time. The reservoir can be rapidly and simply charged by submerging the nozzles (138, 140) in cement and withdrawing the piston to cause intake of cement.
Patent NZ-613802-A (NZ)
Title: Long shelf life milk and milk-related products, and a process and milk processing plant for their manufacture
Inventor: ANDERSEN JOERGEN
IPC: A23C9/152
Filed: 2010-01-27
Abstract: Disclosed herein is a milk or milk-related product wherein at most 40% (w/w) of the beta-lactoglobulin is denatured relative to the total amount of both denatured and nondenatured beta-lactoglobulin, and which milk or milk-related product contains 0 colony forming units/mL. The milk or milk-related product is obtained by a method comprising the steps of: (a) providing a milk derivative, (b) physically separating microorganisms from said milk derivative, preferably by microfiltration, thus obtaining a partly sterilised milk derivative, and (c) exposing a first composition comprising said partly sterilised milk derivative to a High Temperature (HT)-treatment, wherein the first composition is heated to a temperature in the range of 140 – 180 degrees C, kept in that temperature range for a period of at most 200 msec, and then finally cooled.
Patent NZ-616410-A (NZ)
Title: Combination treatment of cancer
Inventor: DAVIES BARRY ROBERT
IPC: A61P35/00
Filed: 2012-04-02
Abstract: The present disclosure relates to a combination comprising (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide also known as AZD5363, or a pharmaceutically acceptable salt thereof, hereafter “Compound (I)”, and a taxane. Taxanes include established cancer drugs such as docetaxel (Taxotere) and paclitaxel (Taxol). Such combinations may be useful in the treatment or prophylaxis of cancer. The disclosure also relates to a pharmaceutical composition comprising such Compound (I) and a taxane. The disclosure further relates to a method of treatment comprising the simultaneous, sequential or separate administration of Compound (I) and a taxane, to warm-blooded animal, such as man. The disclosure also relates to a kit comprising Compound (I) and a taxane, optionally with instructions for use.
Patent NZ-625731-A (NZ)
Title: Methods of modifying antibodies, and modified antibodies with improved functional properties
Inventor: URECH DAVID
IPC: C12N15/13
Filed: 2008-06-25
Abstract: Disclosed is method of engineering an immunobinder, the immunobinder comprising a human Vk3 family light chain variable region, or fragment thereof, the Vk3 family light chain variable region comprising VL framework residues, the method comprising: A) selecting one or more amino acid positions within the Vk3 framework residues; and B) mutating the one or more amino acid positions selected for mutation, wherein the mutating comprises one or more substitutions selected from the group consisting of: wherein if the one or more light chain amino acid positions selected for mutation are of a human Vk3 family light chain variable region, the mutating comprises one or more substitutions selected from the group consisting of: (i) isoleucine (I) at amino acid position 10 using AHo or Kabat numbering system; (ii) tyrosine (Y) at amino acid position 12 using AHo or Kabat numbering system; (iii) serine (S) at amino acid position 18 using AHo or Kabat numbering system; (iv) alanine (A) at amino acid position 20 using AHo or Kabat numbering system; (v) methionine (M) at amino acid position 56 using AHo numbering system (amino acid position 48 using Kabat numbering system); (vi) valine (V) or threonine (T) at amino acid position 74 using AHo numbering system (amino acid position 58 using Kabat numbering system); (vii) asparagine (N) at amino acid position 94 using AHo numbering system (amino acid position 76 using Kabat numbering system); (viii) tyrosine (Y) or serine (S) at amino acid position 101 using AHo numbering system (amino acid position 83 using Kabat numbering system); and (ix) leucine (L) or alanine (A) at amino acid position 103 using AHo numbering (amino acid position 85 using Kabat numbering).
Patent NZ-628248-A (NZ)
Title: Process for the acetylation of wood and acetylated wood
Inventor: ALEXANDER JONATHAN PHILIP
IPC: C08H8/00
Filed: 2013-02-07
Abstract: Disclosed is a process for acetylation of wood comprising: (a) in a reaction pressure vessel submerging wood having a moisture content of less than 5% by weight in an acetylation fluid comprising acetic anhydride and/or acetic acid at a temperature of 10°C to 120°C; (b) increasing the pressure in the vessel to 2 to 20 bar for a period of 1 to 300 minutes; (c) removing excess acetylation fluid from the vessel; (d) introducing into the vessel an inert fluid, circulating and heating the fluid until the internal temperature of the wood begins to show an exotherm, controlling the supply of heat to the wood until the exotherm is complete and maintaining the internal temperature of the wood below 180°C; (e) heating the circulating fluid to a temperature of 85°C to 160°C for a time of 10 to 120 minutes to initiate a second exothermic reaction, controlling the supply of heat to the wood until the exotherm is complete and maintaining the internal temperature of the wood below 180°C; (f) removing the circulating fluid by evaporation under vacuum. The disclosed acetylation process allows the production of acetylated wood having a density of above 400 kg/m3 (e.g., Southern Yellow Pine) having higher acetylation levels, such as an acetyl content of at least 20% by weight. The acetylated wood has also a low residual acetic acid content, in particular, lower than 1% by weight.
Patent NZ-629467-A (NZ)
Title: Back support garment apparatus
Inventor: ARSENAULT JAMES
IPC: A61F5/02
Filed: 2012-01-27
Abstract: A back support system that comprises a belt portion (101) being configured to provide back and abdominal support encircling a wearer’s waist, a compression pants (103) portion and a hot or cold pack providing therapy to a wearer’s lumbosacral region. The belt portion has a left and right portions and a rear portion that extends upwardly from a cutout of the rear portion of the compression pants and is attached fixedly thereto. The rear portion of the belt portion has a pack support structure for receiving a hot or cold pack so as to maintain hot or cold therapy on the wearer’s back. Slots in the belt portion may accommodate vertically extending inserts of rigid plastic or spiral metallic to reinforce the belt portion over the lumbosacral region of the wearer. A front core support structure provides abdominal support in combination with the back support that supports the entire core of the wearer’s body. The garment can be changed to an immobilizing brace device by inserting optional rigid inserts.
Patent NZ-700735-A (NZ)
Title: Transportation and display box
Inventor: ORGELDINGER WOLFGANG
IPC: B65D85/34
Filed: 2010-09-20
Abstract: A box is disclosed comprising a floor and at least two pairs of opposing side walls. One of the side walls (16b) extends upwards from the floor in a vertical direction (18) by a retrieval height which is lower than the height of one or several of the remaining side walls. The lower wall (16b) defines a lateral opening which enables access to products contained in the box. An insert with a plurality of protrusions (54a, 54b) is arranged on the floor of the box to position items which are received in the box. The protrusions (54a, 54b) are higher in a part (76) towards the lower wall (16b) than in a part (75) extending parallel to the lower side wall (16b). The arrangement allows bottles to tilt towards the lower side wall (16b) for removal but prevents tilting parallel to the lower side wall (16b).
Patent NZ-711005-A (NZ)
Title: Grade level enclosure conversion assembly
Inventor: BURKE EDWARD J
IPC: H02G3/18
Filed: 2014-01-08
Abstract: A grade level enclosure conversion assembly adapted for converting a pedestal housing between a flush-to-grade and an above-ground pedestal installation. The base of the pedestal housing carries a plug removably mounted to a swing-arm in the grade level enclosure. The swing-arm holds the pedestal assembly in a stored position in the flush-to-grade installation, containing wiring for service connections. To convert to the above-ground installation, a solid grade level cover plate lid is removed, and the pedestal assembly is rotated on the swing arm to a raised position from which it can be removed from the swing- arm (along with the wiring) and fed through an access opening in a separate cover plate lid. The plug on the pedestal housing is then positioned in the access opening to hold the pedestal assembly in the above-ground position. A series of separate fiber optic splice connections, or other underground utility service connections, can be made when rotating the pedestal between the stored position and the above-ground position.
Patent NZ-712739-A (NZ)
Title: Beta-hairpin peptidomimetics
Inventor: OBRECHT DANIEL
IPC: C07K7/64
Filed: 2014-03-28
Abstract: Beta-hairpin peptidomimetics of the general formula (I), cyclo[P1-p2-p3-p4-p5-p6- p7-p8.p9- p10-p11-p12-T1-T2], a nd pharmaceutically acceptable salts thereof, with P1 to P12, T1 and T2 being elements as defined in the description and the claims, have Gram- negative antimicrobial activity to e.g. inhibit the growth or to kill microorganisms such as Klebsiella pneumoniae and/or Acinetobacter baumannii and/or Escherichia coli. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
Patent NZ-718746-A (NZ)
Title: Container lock system
Inventor: GREEN ROBERT MICHAEL
IPC: B65D90/22
Filed: 2012-09-14
Abstract: ISO container connecting system or twist-lock where rotation of a handle (60) causes a shaft (51) to pass through the ISO corner connector into the adjacent containers corner connector (60) and then rotate to capture the locking lug on the shaft end.
Patent NZ-719737-A (NZ)
Title: Aerosol pirfenidone and pyridone analog compounds and uses thereof
Inventor: SURBER MARK WILLIAM
IPC: A61K31/44
Filed: 2012-01-31
Abstract: Disclosed are formulations of pirfenidone or pyridone analog compounds for nebulised inhlalation adminsitration. Also disclosed is the use of such formulations for the prevention or treatment of various fibrotic and inflammatory diseases, including disease associated with the lung, heart, kidney, liver, eye and central nervous system.