baber/WOPTO huggingface dataset:
Patent EP-0839142-A1 (EP)
Inventor: LI HUI-YIN
IPC: B01J31/24
Filed: 1996-07-10
Abstract: The present invention provides a novel process for making compounds of formula (2a or 2b) or pharmaceutically acceptable salts thereof, wherein R1 is selected from the group consisting of phenyl and phenyl substituted with at least one group selected from NO2 and halogen, R2 is H; R3 is selected from the group consisting of C1-4 alkyl, phenyl, and benzyl; and, R4 is selected from the group consisting of H and halogen; which comprises the steps of: a) oxidizing a racemate of formula (2) or a salt thereof to form a dehydro-compound of formula (3), wherein R5 is selected from the group consisting of H, CH3, benzyl, C2-8 acyl, Na, Li and K; and, b) asymmetrically hydrogenating a compound of formula (3) in the presence of a chiral phosphine catalyst to form a compound of formula (2a or 2b).
Patent EP-0934410-A1 (EP)
Inventor: HASTINGS GREGG A
IPC: C12N1/19
Filed: 1996-10-11
Abstract: L'invention concerne une nouvelle protéine de l'inhibiteur cérébro-associé de l'activateur du plasminogène de type tissulaire (BAIT), laquelle est un membre de la superfamille des serpines, qui s'exprime généralement dans le tissu du cerveau. L'invention concerne notamment des molécules d'acides nucléiques isolées codant la protéine humaine BAIT. On décrit également des polypeptides BAIT en tant que vecteurs et cellules hôtes, ainsi que des procédés de recombinaison aux fins de production de ceux-ci. L'invention concerne encore des procédés de criblage destinés à l'identification des agonistes et antagonistes de l'activité de BAIT, des procédés de diagnostic destinés à détecter des troubles associés au système nerveux, de même que des procédés thérapeutiques destinés au traitement de troubles associés au système nerveux.
Patent EP-0958435-A1 (EP)
Inventor: KARLSSON INGEMAR
IPC: B65H23/022
Filed: 1996-10-09
Abstract: Caisson (2) de soufflage destiné à être utilisé dans une installation pour sécher une bande (2) de matériau, qui comporte une paroi (3) supérieure horizontale dans laquelle sont ménagés des orifices circulaires (5) et des perforations (6) en forme de paupière dont chacune consiste en une fente (7) qui s'étend parallèlement à la ligne centrale (C) de la paroi (3) supérieure et en une dépression (8) formée dans la paroi (3) supérieure adjacente à un côté de la fente. Les perforations (6) en forme de paupière sont disposées en deux rangées parallèles à la ligne centrale (C) et elles forment ensemble un motif en zigzag autour de la ligne centrale (C) qui coupe les dépressions (8) des perforations (6) en forme de paupière des deux rangées. Les orifices (5) sont disposés selon une première et une sonde paire de rangées (9a, 9b et 10a, 10b respectivement), les deux rangées de chaque paire étant placées de chaque côté de la ligne centrale (C) et espacées également par rapport à cette dernière. La paroi (3) supérieure possède une forme légèrement arquée continue sur toute sa largeur.
Patent EP-0864062-A1 (EP)
Inventor: BAKKER ERNST ANTONIUS
IPC: F16L59/18
Filed: 1996-11-27
Abstract: Ce joint articulé flexible (2) comprend une première portion rigide (4) de paroi, une seconde portion rigide (14) de paroi, une portion flexible (12) de paroi s'étendant entre les première et seconde portions rigides (4, 14), ces trois portions délimitant un passage longitudinal à travers le joint et étant disposées sur la longueur du passage, ainsi qu'un manchon (22) fixé au niveau d'une de ses extrémités à la première portion rigide (4), s'étendant à travers le passage de manière à chevaucher la seconde portion rigide (14), espacé de la portion flexible (12) et mobile par rapport à la seconde portion rigide (14). Dans un aspect de l'invention, on a déposé une couche de matériau isolant (24) sur une surface du manchon (22), alors que l'on a laissé sensiblement libre, pour être occupé par un fluide de traitement lors de l'utilisation du joint, l'espace situé entre le manchon (22) et la portion flexible (12). Dans un second aspect de l'invention, la longueur de la portion du manchon (22) chevauchant la seconde portion rigide (14) représente au moins cinq fois la distance séparant le manchon (22) de cette portion (14), distance mesurée perpendiculairement à celui-ci (22).
Patent EP-0882138-A1 (EP)
Inventor: BAILEY MURRAY DOUGLAS
IPC: C07D277/20
Filed: 1996-12-17
Abstract: A highly efficient and practical means has been developed which enables compounds of the formula:   <IMAGE>   wherein R1 is lower alkoxy, lower alkylamino, di-(loweralkyl) amino, or the monovalent radical A-NR3, wherein A is lower alkyl or A is R4R5NC(O)CH2 wherein, for example, R4 is hydrogen or alkyl and R5 is hydrogen, alkyl or a substituted alkyl, or R5 is R6R7N-Alk wherein R6 and R7 each is hydrogen or lower alkyl and Alk is a divalent alkyl radical; R3 is, for example, benzyl, alkyl or a substituted alkyl; and R2 is, inter alia, alkyl, cycloalkyl, 1H-imidazol-4-yl, 4-thiazolyl or 2-amino-4-thiazolyl; to be prepared through the kinetic resolution of a compound of the formula:   <IMAGE>   wherein R1 is as defined herein, R2 is as defined herein, and B is lower alkyl. These compounds are useful intermediates in the synthesis of renin inhibiting compounds.
Patent EP-0870203-A1 (EP)
Inventor: PARL STEEN A
IPC: G01S1/04
Filed: 1996-12-09
Abstract: A position location system includes multiple base stations spaced over a region. A remote unit within the region transmits a locating signal which is received by the base stations. The base stations report amplitude, phase and time data related to the locating signal to a control station. The control station includes a processor and memory that combine the data from all of the participating base stations to directly compute an optimal estimate of the location of the portable unit. The control station generates a locator function based upon the probability that the portable unit is located at a particular position. By optimizing the locator function, the error in the computation is minimized to produce an accurate position estimate.
Patent EP-0789303-A1 (EP)
Inventor: GINSBERG AVI
IPC: G06F13/16
Filed: 1997-02-05
Abstract: A memory system (3) for storing data messages communicated between a processor unit (13) and a communication module (11) comprises a memory array (4) having a plurality of memory buffers (B0-BM) for storing the data messages. First logic circuitry (28) generates a lock signal for a memory buffer which lock signal is valid when the processor unit (13) reads the first data word of the data message stored in the memory buffer whilst the memory buffer is not being accessed by the communication module (11). Module decode logic (22) coupled to receive the lock signal prevents the communication module (11) from writing a data message to a memory buffer when a valid lock signal has been generated for that memory buffer. The memory system (3) further comprises second logic circuitry (30) for providing a busy signal to the processor unit (13) when the processor unit reads the first data word from a memory buffer. The busy signal forms part of the first data word read from the memory buffer, and its logic state indicates whether or not the memory buffer is being written to by the communication module (11).
Patent EP-0822107-A1 (EP)
Inventor: TANAKA KATSUTO
IPC: G02B1/11
Filed: 1997-07-25
Abstract: The invention relates to a vehicular glass pane having
inner and outer major surfaces which are respectively disposed
on a first side of a vehicular interior and a second side of a
vehicular exterior. The glass pane has a glass plate and a
multilayered film formed on one of the inner and outer major
surfaces of the glass plate. The glass plate contains a coloring
agent. The multilayered film includes a first layer which is
light-absorbent and a second layer which is non-light-absorbent.
The glass plate and the multilayered film are such that a visible
light transmittance of the glass pane is from 25 to 55%, that a
first reflectance of the inner major surface of the glass pane is
up to 15%, that a second reflectance of the outer major surface of
the glass pane is from 10 to 40%, that the visible light
transmittance minus the first reflectance is at least 15%, and
that the visible light transmittance minus the second
reflectance is up to 30%. The glass pane is capable of
sufficiently maintaining the vehicular occupants' privacy
therethrough and the outward visibility therethrough from the
vehicular interior, under various conditions.
Patent EP-0834857-A1 (EP)
Inventor: OKAMOTO KOHEI
IPC: G02F1/133
Filed: 1997-09-25
Abstract: A display driver includes a column driver (3, 4)
including a decoder (6) and a plurality of analog
switches (7A, 7B, 7D). One (7D) of the analog switches
(7A, 7B, 7D) which outputs a voltage of the lowest
potential (V ⊘ ) is formed from an nMOS field effect
transistor (Q N⊘ ) connected between a potential supply
point of the lowest potential to be outputted and an
output point (Y) so as to form a current path. The back
gate electrode of the MOS field effect transistor is
connected to the potential supply point of the lowest
potential. A level shift circuit (11) level shifts a
lower side potential from among output signals of the
decoder to the lowest potential to be outputted and
provides the level shifted signal to the gate electrode
of the MOS field effect transistor.
Patent EP-0837081-A1 (EP)
Inventor: HEINEMANN HERBERT
IPC: C08G18/38
Filed: 1997-10-11
Abstract: A method for the preparation of a polyurethane hard foam thermal insulation material, especially suitable for use in buildings, comprises adding polyol and isocyanate components to a mixer linked to an insulation material moulding device. Powdered water glass with a SiO2/alkali oxide mass ratio of ca. 2:0.8-1.2, particle size less than 0.4 mm and bulk weight greater than 500 p/l is added to one or both of the components before they are mixed together, to form a slurry containing up to 60 wt.% water glass in either or both of the two components and also in the resulting mixture. Water is added to the polyol both of the components prior to mixing, depending on the amount of water glass, in order to react with isocyanate and form carbon dioxide, some of which reacts with the water glass to form silica.
Patent EP-0846921-A1 (EP)
Inventor: SCHULTHEISS BERND
IPC: F24C15/10
Filed: 1997-11-21
Abstract: The arrangement comprises a continuous elastic layer (3) that is arranged around the underside of a sloped, chamfered edge area (1a) of the cooker surface (1) and around the edge face of the thin edge (1b) of the cooker surface. The arrangement is frame-like and is designed so that the edge is not exposed to a direct mechanical impact stress from the side or above. The edge protection (3a) is approximately 0.5 mm thick and is bonded to the edge of the ceramic. The elastic support layer under the edge is approximately 1.5 mm thick. A hard energy-dissipating layer (2) is integrally fixed to the to a section of the work surface.
Patent EP-0846683-A1 (EP)
Inventor: ALANINE ALEXANDER
IPC: C07D401/06
Filed: 1997-12-01
Abstract: The present invention relates to 4-hydroxy-piperidine derivatives of the
general formula
 
wherein
     X   denotes -O-, -NH-, -CH 2 -, -CH=, -CHOH-, -CO-, -S-, -SO- or -SO 2 -;   R 1 -R 4     are, independently from each other, hydrogen, hydroxy, lower-alkyl-sulfonylamino,
1- or 2-imidazolyl or acetamido;   R 5 -R 8     are, independently from each other, hydrogen, hydroxy, lower-alkyl,
halogen, lower-alkoxy, trifluoromethyl or trifluoromethyloxy;   a and b   may be a double bond, provided that when "a" is a double bond,
"b" cannot be a double bond;   n   is 0-2;   m   is 1-3;   p   is 0 or 1   
and to pharmaceutically acceptable addition salts thereof.
     Compounds of the present invention are NMDA(N-methyl-D-aspartate)-receptor
subtype selective blockers, which can be used in mediating
processes underlying development of CNS including learning and memory
formation and function.
Patent EP-0796826-A1 (EP)
Inventor: THOMAS BRYAN
IPC: C08L83/05
Filed: 1997-03-13
Abstract: A method for preparing an aqueous gypsum mixture having hydrophobic additive substantially uniformly dispersed therein, which method comprises admixing in water gypsum, a silane of the general formula (RO) 3 SiR' or the general formula (RO) 2 SiRR', and non-emulsified polysiloxane of the general formula;
      wherein each R is the same or different and represents a hydrocarbon group having from one to eight carbon atoms, R' represents a lower alkyl group which is optionally substituted by an amino, amino-loweralkylene-amino or dialkylenetriamine group, and  a  has an average value of between 20 and 200. The silane is preferably N-(2-aminoethyl)-3-aminopropyltrimethoxysilane and the polysiloxane preferably trimethyl end-blocked linear methylhydrogen polysiloxane. The method may further include adding surfactant. Also disclosed is a gypsum product which includes gypsum mixture prepared according to the above method.
Patent EP-0913512-A1 (EP)
Inventor: NEWGAS JOHN RICHARD
IPC: D04D7/08
Filed: 1997-10-23
Abstract: Individual tassels are produced by laying groupsof loops of tassel
tuft yarn (E) into warp stitch chains at opposite ends of the loops, an
elastic material (A,B) being used for the stitch chain or chains at one
end. A further yarn (D) is laid in loops extending from the elastic
stitch chain or chanis and away from the tuft loops to provide a hinging
loop for each group of tuft loops. The ends of the loops of the further
yarn re each woven into a plurality of stitches of the or each elastic
stitch chain. Severing the elastic stitch chain or chains and removal of
the stitch chain at the other end of the tuft loops together with the
loop bends at that end yields a series of separate tassels each with a
securely attached hanging loop. The invention also includes apparatus
for producing individual tassels.
Patent EP-0811396-A1 (EP)
Inventor: LEE CHIK YAM
IPC: A61N1/372
Filed: 1997-06-04
Abstract: The filtering device (26) includes an input for receiving a signal passed to it by a receiver circuit (16-24). This signal is emitted in the form of a magnetic induction signal from a medical apparatus in a metallic box. A compensation stage (42) has a transfer function in the frequency domain in the form: psi(f) = 1+ j(f/fc) fc is a parameter which is chosen based upon a geometry and material of the metallic box. The medical apparatus sends messages in the form of sequences of elementary symbols. These symbols are part of an alphabet of n symbols.
Patent EP-0844812-A1 (EP)
Inventor: DUBELLOY JEAN-LUC
IPC: H05K7/20
Filed: 1997-11-17
Abstract: In a cooling device for IGBT components, the IGBT component (1) is positioned on a cooling element (2) of insulating and thermally conductive material, through which water circulation channels (3) pass, both the IGBT component (1) and the cooling element (2) being located in a holder plate (4) of insulating material.
Patent EP-0784953-A1 (EP)
Inventor: BERNAULT JEAN-FRANCOIS
IPC: A47C7/16
Filed: 1997-01-09
Abstract: The seat (1) has its base and back (4a,4b) made in the form of a steel, aluminium or composition material structure (2), covered with a layer (3) of wood or plastic which is stuck to the structure (2) in a vacuum, using an epoxy-type adhesive. The upper surface of the structure (2) and the under-surface of the covering layer are coated with the resin adhesive and joined together on a support covered by a layer of polyethylene sheet, while the air beneath the sheet is extracted by a vacuum pump.
Patent EP-0817232-A1 (EP)
Inventor: BANCAL BERNARD
IPC: H01J9/50
Filed: 1997-07-01
Abstract: The grid is biased to a regeneration potential distinctly greater than the nominal potential and the cathode is biased to a nominal potential corresponding to a maximum emission. The rows (L) of the grid are addressed in sequence during a nominal time during which the cathode columns (K) are individually addressed. At least one row, perhaps all, of the grid is biased to a the regeneration potential and all the cathode columns are at the maximum emission potential for a regeneration time distinctly greater than the nominal time. The rows are addressed by a pulsed signal (Hreg) whose mark is distinctly longer than the nominal time and distinctly shorter than the space time to avoid overheating.
Patent EP-0888310-A1 (EP)
Inventor: THOMAS ANDREW PETER
IPC: C07D237/28
Filed: 1997-03-11
Abstract: L'invention a trait à l'utilisation de dérivés de cinnoline répondant à la formule (I) dans laquelle Z représente -O-, -NH-, -S- ou -CH2, m est un nombre entier compris entre 1 et 5, R1 représente un hydrogène, un hydroxy, un halogéno, un nitro, un cyano, un trifluorométhyle, un alkyle en C¿1?-C3, un alkoxy en C1-C3, un alkylthio en C1-C3 ou NR?6R7 (R6 et R7¿, pouvant être identiques ou différents, représentent chacun un hydrogène ou un alkyle en C¿1?-C3), R?2¿ représente un hydrogène, un hydroxy, un fluoro, un chloro, un méthoxy, un amino ou un nitro, R3 représente un hydroxy, un halogéno, un alkyle en C¿1?-C3, un alkoxy en C1-C3, un alkanoyloxy en C1-C3, un trifluorométhyle, un cyano, un amino ou un nitro, R?4¿ représente un hydrogène, un hydroxy, un halogéno, un cyano, un nitro, un amino, un trifluorométhyle, un alkyle en C¿1?-C3 ou un groupe R?5-X1(X1¿ représentant -O-, -CH¿2?-, -S-, -SO-, -SO2-, -NR?8¿CO-, -CONR9-, -SO¿2?NR?10-, -NR11SO¿2- ou -NR?12- (R8, R9, R10, R11 et R12¿ représentent chacun, de manière indépendante, un hydrogène, un alkyle en C¿1?-C3 ou un alkoxy en C1-C3 - alkyle en C2-C3) et R?5¿ représente un alkyle éventuellement substitué, un groupe carbocyclique ou hétérocyclique pouvant être saturé ou insaturé et pouvant être lié directement au noyau cinnoline ou lui être lié par l'intermédiaire d'une chaîne carbone susceptible de renfermer des groupes hétéro-atomiques de liaison. Cette invention, qui porte également sur des sels de ces dérivés, a trait, en outre, à l'élaboration d'un médicament utilisé pour induire un effet anti-angiogénique et/ou réduire la perméabilité vasculaire chez un animal à sang chaud, un être humain par exemple. Elle concerne, de surcroît, la préparation des dérivés susmentionnés, de compositions pharmaceutiques contenant un composé de la formule (I) ou un sel acceptable du point de vue pharmaceutique de celui-ci comme ingrédient actif ainsi que de composés de la formule (I). Les composés répondant à la formule (I) et leurs sels acceptables du point de vue pharmaceutique inhibent les effets du facteur de croissance de l'endothélium vasculaire, ce qui est une propriété des plus appréciable pour le traitement d'un certain nombres d'états pathologiques parmi lesquels figurent le cancer et la polyarthrite rhumatismale.
Patent EP-0889889-A1 (EP)
Inventor: FEENSTRA ROELOF WILLEM
IPC: A61K31/5513
Filed: 1997-03-20
Abstract: The invention relates to a group of new piperazine and piperidine compounds having interesting pharmacological properties. It has been found that compounds of formula (a) wherein A represents a heterocyclic group of 5-7 ring atoms wherein 1-3 heteroatoms from the group O, N and S are present; R1 is hydrogen or fluoro; R2 is C1-4-alkyl, C1-4-alkoxy or an oxo group, and p is 0, 1 or 2; Z represents carbon or nitrogen, and the dotted line is a single bond when Z is nitrogen, and a single or double bond when Z is carbon; R3 and R4 independently are hydrogen or C1-4-alkyl; n has the value 1 or 2; R5 is halogen, hydroxy, C1-4-alkoxy or C1-4-alkyl, and q is 0, 1, 2 or 3; Y is phenyl, furanyl or thienyl, which groups may be substituted with 1-3 substituents of the group hydroxy, halogen, C1-4-alkoxy, C1-4-alkyl, cyano, aminocarbonyl, mono- or di-C1-4-alkylaminocarbonyl; and salts thereof show high affinity for both the dopamine D2 and serotonin 5-HT1A receptors.
Patent EP-0934186-A1 (EP)
Title: Headlight cleaning system operating exclusively by spraying with washing liquid
Inventor: BANDEMER JOACHIM
IPC: B60S1/48
Filed: 1997-10-06
Abstract: The invention concerns a system for cleaning motor vehicle headlights (2) simply by spraying with washing liquid, the system comprising a plurality of washer nozzles (12 - 14) which are disposed on a washer arm (6) which can pivot about a pivot pin (7), the washer nozzles (12 - 14) being located at a slight spacing opposite the headlight (2) and together spraying a partial region thereof with washing liquid, the washer arm (6) guiding the washer nozzles (12 - 14) over the region of the headlight (2) to be cleaned.
Patent EP-1007155-A1 (EP)
Inventor: YAVITZ EDWARD Q
IPC: A41D13/11
Filed: 1997-03-14
Abstract: L'invention concerne un masque chirurgical (10) pour couvrir le nez et la bouche d'une personne. Ce masque (10) est prévu pour faciliter l'écoulement d'air par le nez. Le masque comprend une bande adhésive rigide (26) qui, une fois fixée sur le nez, ouvre les voies nasales pour laisser plus d'air passer dans ces dernières. En outre, la bande adhésive rigide (26) empêche l'air exhalé de s'échapper par le sommet (14) du masque et de se condenser sur les lunettes de l'utilisateur ou toute autre surface.
Patent EP-0890191-A1 (EP)
Inventor: HARRIS CHRISTOPHER
IPC: H01L29/78
Filed: 1997-03-26
Abstract: L'invention concerne un transistor bipolaire à grille isolée (IGBT) comprenant un drain (1), une couche de substrat fortement dopée P (2), une couche tampon fortement dopée N (3), une couche de migration (4), une couche de base P (5), une couche de la région source fortement dopée N (6) et une source (7). Une tranchée (8) est formée par attaque chimique dans la couche de base. Le transistor comporte également une couche isolante (9) ainsi qu'une électrode de grille (10) disposée sur la couche de base et s'étendant de la couche de la région source (6) à la couche de migration (4) afin de former un canal d'inversion conducteur; une partie de contact (11), séparée verticalement de la couche de la région source (6) et supportant la source (7) permet de recueillir les trous injectés de la couche de substrat à la couche de migration, à une distance verticale de la couche de la région source (6).
Patent EP-0892951-A1 (EP)
Inventor: VELA OSCAR GUSTAVO
IPC: H03M13/27
Filed: 1997-03-27
Abstract: Appareil et procédé permettant de désentrelacer des blocs de données dont chacun est transmis comme une séquence de groupes de données incluant N bits de données d'une position d'un seul bit de N mots. Un premier bloc de données est reçu (1004) et stocké (1006) en mémoire (402) de façon à définir les emplacements de mémoire de chacun des N mots, ce qui permet de désentrelacer un premier bloc de données. La réception du bloc de données suivant se fait au moyen du traitement (1008) d'une partie au moins des N mots préalablement stockés en mémoire, ce qui permet d'avoir des emplacements de mémoire libres, et de la réception (1012) par la suite de nouvelles données incluant au moins une partie du groupement suivant de données du bloc de données suivant. Lorsque les nouvelles données sont stockées (1014) dans une partie au moins des emplacements de mémoire libres, le traitement continue jusqu'à ce que le bloc de données suivant ait été reçu et stocké dans son intégralité. Les emplacements de mémoire sont alors redéfinis (1018) pour les N mots, ce qui désentrelace le bloc de données suivant.
Patent EP-0895588-A1 (EP)
Inventor: BRUINS HANS JOACHIM
IPC: G01N21/25
Filed: 1997-04-21
Abstract: The invention relates to a distribution device, in particular for use during reactions in the chemical processing industry. Said device contains distribution means (210) for investigating a plurality of sample regions and used to distribute a sample signal simultaneously to a plurality of conductor means (202) which are each connected to probes (204) in a reaction chamber (50).
Patent EP-0889991-A1 (EP)
Inventor: MUELLER JOST HENNING
IPC: D21F5/06
Filed: 1997-03-27
Abstract: In order to avoid the use of heat transfer fluids flowing through peripheral heating channels of heated calender rollers, supporting tubes (4) made of a soft elastic plastic are provided inside the heating channels (3). A resistance-heated or induction-heated wire (6) is extruded into the wall (5) of the supporting tubes (4).