baber/WOPTO huggingface dataset:
Patent EP-0479920-A1 (EP)
Inventor: HELLSTROM INGEGERD
IPC: A61K47/48
Filed: 1990-06-29
Abstract: L'invention concerne de nouveaux anticorps réagissant avec des cellules de carcinome humain. Plus particulièrement, les anticorps de l'invention comprennent: un anticorps monoclonal murin, le BR96; un anticorps chimérique humain/murin, le ChiBR96; et un fragment F(ab')2 de BR96. Ces anticorps réagissent avec un antigène de membrane cellulaire présent sur la surface des carcinomes humains. Les anticorps présentent un degré élevé de sélectivité pour les cellules de carcinome et possèdent la capacité de médiation de l'activité ADCC et CDC. En outre, les anticorps de l'invention s'internalisent à l'intérieur des cellules de carcinome auxquelles ils se lient et sont donc particulièrement utiles aux applications thérapeutiques, par exemple, en tant que composant anticorps des conjugués anticorps-médicament et anticorps-toxine. Les anticorps possèdent également une caractéristique unique en ce qu'ils sont cytotoxiques lorsqu'ils sont utilisés en forme inchangée, à des concentrations spécifiées.
Patent EP-0441959-A1 (EP)
Inventor: JACOBS JAMES R
IPC: A61M5/00
Filed: 1990-08-28
Abstract: Une méthode et un appareil pour contrôler un procédé à circuit ouvert géré par modèle et, plus précisément, la concentration d'un médicament introduit intraveineusement dans un patient en fonction de la vitesse de l'administration. On utilise de préférence un modèle pharmacocinétique à trois compartiments pour déterminer les concentrations de médicament de plasma correspondant à deux vitesses d'administration arbitrairement choisies. Un microprocesseur (100) détermine une vitesse interpolée en fonction d'une concentration de médicament de plasma spécifique selon des étapes de programmation stockées dans une mémoire morte (ROM) (104), à partir du rapport linéaire entre des paires de données correspondantes. Chaque paire de données comprend une vitesse d'administration et une concentration de médicament de plasma correspondante. On utilise à répétitions la vitesse réelle d'administration du médicament lors d'intervalles successifs de manière à calculer la concentration de médicament de plasma à la fin de chaque intervalle. A chaque itération successive, on utilise des variables d'état provenant du calcul antérieur de la concentration de médicament de plasma pour déterminer la vitesse d'administration interpolée suivante. Toute interruption de la sortie par un dispositif d'administration (112) ainsi que des modifications issues de la valeur interpolée de la vitesse d'administration sont compensées. On obtient rapidement la concentration de plasma spécifiée, en utlisant la méthode et l'appareil de contrôle à circuit ouvert décrits.
Patent EP-0494955-A1 (EP)
Inventor: KAWASAKI GLENN H
IPC: C12N15/09
Filed: 1990-10-04
Abstract: A method for the cell-free synthesis and isolation of novel genes and polypeptides is provided. Within one embodiment, an expression unit is constructed onto which semi-random nucleotide sequences are attached. The semi-random nucleotide sequences are first transcribed to produce RNA, and then translated under conditions such that polysomes are produced. Polysomes which bind to a substance of interest are then isolated and disrupted; and the released mRNA is recovered. The mRNA is used to construct cDNA which is expressed to produce novel polypeptides.
Patent EP-0457212-A1 (EP)
Inventor: MISHIMA MASAYUKI
IPC: C07F7/08
Filed: 1991-05-10
Abstract: The present invention is directed to a silicon-containing triarylamine compound represented by the formula (1):
       
 wherein Q₂ and Q₃ independently represent a hydrogen atom or -CH₂SiR₁R₂R₃ group (R₁, R₂ and R₃, which may be identical or not, independently represent an alkyl group, cycloalkyl group, aralkyl group or aryl group which may be substituted); Ar₁, Ar₂ and Ar₃ independently represent an arylene group which may be substituted; Q₁ represents a -CH₂SiR₁R₂R₃ group, -CH₂SiR₁R₂R₄ group (R₄ represents the following:
       
 wherein Q₂ and Q₃ independently represent a hydrogen atom) or -CH₂SiR₁R₄R₄ group, a method of its production and a photoreceptor for electrophotography incorporating it as a charge transport material. The photoreceptor is very excellent in sensitivity and durability.
Patent EP-0476485-A1 (EP)
Inventor: MOHR JUERGEN DR
IPC: C10M133/52
Filed: 1991-09-10
Abstract: Polyisobutylaminoalcohols, method for making them and internal combustion engine fuels or lubricants containing small amounts of these compounds of the formulae Ia and Ib <IMAGE>  in which R denotes a polyisobutyl radical having a molecular weight (number average) of 500 to 5000 and in both formulae in each case one of the radicals X denotes an OH group and the other radical X denotes the group <IMAGE> where the radicals R<1> can be identical or different and denote hydrogen, alkyl, hydroxyalkyl or aminoalkyl, which can also be substituted by further alkyl radicals carrying hydroxyl or amino groups, or in which the two radicals R<1> can form a non-aromatic ring.
Patent EP-0483613-A1 (EP)
Inventor: GERSTEL EBERHARD
IPC: G01N30/06
Filed: 1991-10-18
Abstract: A description is given of a process and an apparatus for the qualitative and/or quantitative monitoring of starting material in the form of substances in a liquid phase which are taken up in a carrier gas and fed to an analyser, possibly via a gas-chromatographic capillary column. In order to be able to analyse the spectrum of the substances being monitored with as low loss as possible, a defined amount of starting material is fed into a narrow extractor space (7) which is elongated in an essentially vertical direction, the carrier gas is allowed to bubble from below through the liquid starting material in the extractor space and the loaded carrier gas is fed to an evaporator tube (15) which can be cooled and heated and whose temperature setting is such that a liquid phase it contains retains the substances to be monitored, while entrained evaporated starting-material liquid phase is removed, at least predominantly, with the carrier gas. The substances retained in the evaporator tube are then released by heating the evaporator tube with free access to the capillary column (17) or to the analyser and are fed into the capillary column or the analyser by means of the carrier gas. <IMAGE>
Patent EP-0461704-A1 (EP)
Inventor: VAN DEN BERG ANTONIE
IPC: G01M99/00
Filed: 1991-06-04
Abstract: Current systems to measure the noise running behaviour of grease in a bearing arrangement is time consuming and rather complicated due to the fact that for the test of one grease type several bearings, for statistical reasons, have to be filled with this grease, tested and thereafter thoroughly cleaned for the next grease tests. To simplify and moreover to reduce the equipment costs as well as the operating time improved test-arrangement has been developed. A test bearing (1) is mounted on the spindle (4). A suitable detector (5) linked to a measuring and registration system (not shown) is connected with the bearing. Bearing (1) and spindle (4) are provided with a special adapter (6) which mainly comprises of a support member (7) to which a grease collector (9) is bolted. The support (7) is provided with a grease-inlet (10) comprising a special dosing system and an air-inlet (16). When a certain amount of grease via inlet (10) is brought in the running bearing (1) and the grease behaviour registered according to prescribed procedures, the tested grease amount by air via inlet (16) now can be cleanly blown-off from the bearing arrangement (1,4) which then becomes suitable for the following tests.
Patent EP-0439249-A1 (EP)
Inventor: KNIFTON JOHN FREDERICK
IPC: B01J23/86
Filed: 1991-01-04
Abstract: Tertiary amines having the formula:
       
 wherein x is 1 to 30, R is alkylphenyl or alkyl having 4 to 20 carbon atoms, and R' is n-alkyl having 1 to 6 carbon atoms, having good surface active properties, can be synthesized by reacting an alkylamine of the formula R'-NH₂ and an oxyalkylated alkyl phenol or alcohol of the formula HO-CH₂CH₂-(OCH₂CH₂) x -OR in the presence of a catalyst comprising a nickel compound on a support comprising one or more elements from Group III or IV of the Periodic Table or a copper compound.
Patent EP-0444942-A1 (EP)
Inventor: ITO TATSUO
IPC: H01L21/02
Filed: 1991-02-28
Abstract: A bonded wafer comprising a filmy bond wafer (1), a base wafer (2), and an intermediate silicon dioxide layer (3), wherein the periphery of the bond wafer (1) is etched; this bonded wafer is made by subjecting the bond wafer to an oxidation treatment to form an oxide film over it; joining the two wafers in a manner such that the oxide film-covered face of the bond wafer is put on the base wafer to thereby sandwich the oxide film between the wafers; heating the combined wafers to thereby create a bonding strength between the two wafers; grinding the exposed face of the bond; etching the periphery of the bond wafer to remove the portion which is not in contact with the base wafer; and polishing the exposed face of the bond wafer until it becomes a thin film.
Patent EP-0453288-A1 (EP)
Inventor: BLACKLOCK THOMAS J
IPC: A61K31/38
Filed: 1991-04-18
Abstract: 5,6-Dihydro-4-(R-amino)-4H-thieno[2,3-b]-thiopyran-2-sulfonamide-7,7-dioxide is a potent carbonic anhydrase inhibitor useful in the treatment of ocular hypertension and glaucoma. The S-(+)-enantiomer of that compound, the more active enantiomer, is prepared by a process involving an intermediate step of an enantioselective reduction of a carbonyl group employing an oxazaborolidine chiral catalyst.
Patent EP-0512164-A1 (EP)
Inventor: OWEN HARTLEY
IPC: B01J29/90
Filed: 1991-05-02
Abstract: In apparatus for fractionation of a superheated vapor from a riser cracking FCC reactor (4), the vapor is charged via transfer line (11) to the upper section (230) of a two-part fractionation column (130, 230). In the upper section (230), the superheated vapor contacts and vaporises a liquid fraction recycled from the lower section (130) of the column. The resultant vaporized liquid is discharged as a vapor fraction to the base of the lower section (130), where it is then fractionated to provide the required liquid hydrocarbon fractions.
Patent EP-0474510-A1 (EP)
Inventor: OHARA MAMORU
IPC: B61D17/10
Filed: 1991-09-06
Abstract: The disclosure relates to a railway car body structure adapted to run at a high speed, and a production method thereof. To reduce vibration and noise and to prevent influences of outdoor pressure variations on passengers in the case of a high-speed railway car, the weight of the car body structure must be reduced and its pressure resistance must be improved. Each of the side constructions (2), roof construction (4) end constructions (5) and floor plates of an underframe (3) is constituted by plate members obtained by joining two surface sheet materials, a core material e.g. honeycomb sheet, and elongate joining members and through metal-to-metal bonding, the sheet thickness of the surface material on an outdoor side being made greater than that of the surface material on an indoor side. Also described is a production method of a body structure wherein the plate members are constituted as a block and a plurality of blocks are joined so as to constitute the side constructions, roof construction or the floor plates of the underframe described above.
Patent EP-0442790-A1 (EP)
Inventor: MARCONNET GUY LA CHAMPAGNIERE
IPC: E01C19/10
Filed: 1991-02-08
Abstract: Cold and wet aggregates (4) are continuously introduced into a drying zone (7). The aggregates and hot gases are circulated countercurrentwise in the drying zone (7). The dried and heated aggregates are continuously introduced into a mixing zone (16) through which the hot gases do not travel. Liquid bitumen is incorporated into the aggregates in the mixing zone (16). The aggregates are circulated and they are mixed with the bitumen during their circulation in the mixing zone (16). During coating, the aggregates are kept in the mixing zone (16) during certain phases at least of production, by closure of a discharge means (21) communicating with the exit from the mixing zone (16). <IMAGE>
Patent EP-0466526-A1 (EP)
Inventor: SAINTON ALAIN
IPC: C08J9/30
Filed: 1991-05-17
Abstract: a) Bituminous binder for road surfacing and process for the manufacture of such a binder, b) the binder is characterised in that it consists of a bitumen emulsion expanded with air and the process is characterised in that a bitumen emulsion heated in an expansion device is expanded by mechanically inserting air under pressure therein. <IMAGE>
Patent EP-0461983-A1 (EP)
Inventor: ANGEBAUD DIDIER
IPC: H04L9/32
Filed: 1991-06-10
Abstract: According to the invention, the chip card sends out a first certificate grouping together its credentials (Crc), an exponential (X), an optional message (M), these quantities being signed. The safety module checks the signature and sends back by return a second certificate containing its credentials (Crm), an exponential (Y), an optional message (M'), a cryptogram (C), these quantities being signed. A common, secret key is constituted between the card and the safety module by the exponentials and permits the card to interpret the cryptogram which is addressed to it and to act in consequence. Application to chip cards.
Patent EP-0481899-A1 (EP)
Inventor: GUEZENNEC YANNICK
IPC: A61K31/70
Filed: 1991-10-18
Abstract: The present invention relates to a dietary composition intended to be absorbed before, during or after an effort, characterised in that it comprises glucids and lipids, the said lipids forming 10 to 55% of the calorie content of the composition.
Patent EP-0443987-A1 (EP)
Inventor: KUDELSKI ANDRE
IPC: H04N7/169
Filed: 1991-02-21
Abstract: Method and device for scrambling and descrambling of a video signal, in which, at reception level, there is provided a memory (8) comprising a specified number of memory lines, each memory line being able to store one received image line having undergone, at transmission level, a certain rotation, the storing of an image line thus received (Z) being done in such a way as to bring about the removal from storage and the sending to a television of the image line previously stored (X) in the memory line having undergone another rotation, this removal from storage being done according to the normal order of the rotation-free image line, so that this image line (X) is sent directly to the television to form the image in clear. <IMAGE>
Patent EP-0453411-A1 (EP)
Inventor: BOTTERON JEAN-DANIEL
IPC: B23B13/02
Filed: 1991-04-19
Abstract: The device comprises a tubular guide element in which the bar is placed, means for pushing this bar into this element and means for feeding it quickly and accurately to the turning tools. The tubular element (12), which has an internal diameter slightly greater than that of the bar (13) and a length greater than that of this bar, contains a piston (40), connected by a cable (41) to an automatic winder (42), by which the bar (13) may be pushed. A sealed cap (19a) closes the element (12) and comprises an injection nozzle (26) through which a liquid may be injected behind the bar to drive it forward. By means of a piston (31) housed inside an actuator (32) it is possible, via a rod (30), to open and close the cap (19a). <IMAGE>
Patent EP-0473542-A1 (EP)
Inventor: STEINBERG DAVID H
IPC: C08K5/378
Filed: 1991-08-09
Abstract: Thioaminal compounds of the indicated formulae are effective in stabilizing organic materials against oxidative and thermal degradation, said compounds particularly imparting exceptional oxidative stability to various organic substrates such as lubricants and elastomers; and certain of said compounds as novel compounds.
Patent EP-0544967-A1 (EP)
Inventor: HERREN GEORGES
IPC: C21C5/52
Filed: 1991-11-28
Abstract: To suppress dust and fumes in electric steel production in an electric melting furnace during the melting of iron products, such as raw iron, scrap iron directly reduced iron pellets and various alloying metals or mixtures thereof with widely fluctuating impurities, solid CO2 is passed into the melting vessel just before, during and after charging. In this way, the explosive combustion of the combustible constituents is prevented, since the oxygen is displaced during the charging step by the expanding gaseous CO2 being formed. <IMAGE>
Patent EP-0470946-A1 (EP)
Inventor: CHAMBLEE WAYNE
IPC: B03D1/14
Filed: 1991-08-06
Abstract: The removal of sticky contaminants and/or ink particles during the production of recycled paper is accomplished utilizing a hydrocyclone (31) froth flotation process. Paper having sticky contaminants from labels, tapes, hot melts, and other tacky substances, and/or print, is reduced to a finely comminuted liquid solids suspension of about 1-4% consistency (preferably over 2%). The suspension is introduced into a first end (44) of a vortex (41) in a hydrocyclone (31), and the air is sparged radially inwardly into the suspension vortex by passing it through a porous inner wall (47) of the hydrocyclone. Lighter weight sticky contaminants move to the center of the hydrocyclone, facilitated by the radially inward movement of the sparging air, and hydrophobic sticky contaminants and/or ink particles attach to the air bubbles and form a foam. The foam and lightweight sticky contaminants are removed from the first end (at 33, thru 51) of the vortex, while the pulp which has had sticky contaminants and/or ink removed therefrom is discharged from the second end of the vortex (at 32), opposite the first end. A plurality of vertical axis hydrocyclones (21) may be connected together in series, with a plurality of the series connected in parallel, to provide the most effective treatment. Removal of sticky contaminants can be practiced prior to or simultaneously with deinking (Figure 3).
Patent EP-0502113-A1 (EP)
Inventor: NHO KWANG
IPC: A61K38/00
Filed: 1990-11-21
Abstract: Hémoglobine modifiée chimiquement, produite selon un procédé nouveau et efficace, dans lequel l'hémoglobine exempte de stroma est premièrement désoxygénée et réduite efficacement, puis est conjuguée à un oxyde de polyalkylène tel que du polyéthylène-glycol (PEG) dans des conditions maintenant l'intégrité structurelle du site de liaison d'oxygène de hème. Dans des modes de réalisation préférés spécifiques de l'invention, la désoxygénation et la réduction ont lieu en atmosphère inerte à l'aide de la cystéine d'acides aminés. Dans d'autres modes de réalisation préférés spécifiques, l'intégrité structurelle du site de liaison d'oxygène de hème, est maintenue par une forte concentration anionique dans le mélange de réaction. Selon d'autres modes de réalisation préférés, spécifiques, de l'invention, l'oxyde de polyalkylène est du polyéthylène-glycol; d'autres modes de réalisation préférés spécifiques, de l'invention prévoient que l'oxyde de polyalkylène est lié à de l'hémoglobine par l'intermédiaire d'une liaison uréthane (carbamate). Les nouveaux composés d'hémoglobine modifiée par du PEG de l'invention, présentent des capacités de transport d'oxygène supérieures, une demi-vie prolongée, et notamment une faible immunogénicité.
Patent EP-0514446-A1 (EP)
Inventor: FREEMAN STEPHEN
IPC: G06T11/20
Filed: 1991-02-07
Abstract: Un système graphique comprend un dispositif d'entrée (31); un détecteur pour détecter le mouvement du dispositif d'entrée par rapport à une surface (5); et un dispositif d'affichage pour afficher des dessins qui suivent le mouvement du dispositif d'entrée pour simuler la création de dessins sur une surface à l'aide d'un instrument de dessin. Le système comporte une mémoire (21) pour stocker des caractéristiques qui définissent un certain nombre d'instruments de dessin et des moyens de commande pour choisir dans la mémoire les instruments de dessin qui doivent être utilisés par le moyen d'affichage pendant le mouvement du dispositif d'entrée, plus d'un instrument de dessin pouvant être utilisé pendant un seul mouvement du dispositif d'entrée.
Patent EP-0465647-A1 (EP)
Inventor: HENRY CLARK A
IPC: F16L37/26
Filed: 1991-01-18
Abstract: Accouplement à glissement de connexion/déconnexion rapide à composants multiples (14, 17) actionnable à distance pour pompe de matières fécales avec passage d'accès étroit comprenant une partie fixe qui forme un premier composant (14, 14a) d'un accouplement à glissement du type à baïonnette avec une partie mobile (17) formant un second composant de l'accouplement. La partie mobile (17) de l'accouplement supporte une pompe pour liquides et coulisse ensemble avec la partie fixe qui la supporte. Avec cette conception, une portion intermédiaire (18) d'une vanne à tiroir de l'accouplement peut être déplacée indépendamment d'une seconde portion mobile (17) de l'accouplement à glissement sur lequel la pompe est supportée à l'intérieur d'un conteneur (11).
Patent EP-0518916-A1 (EP)
Inventor: KIRKPATRICK WILLIAM R
IPC: G08C19/02
Filed: 1991-02-21
Abstract: Un émetteur de traitement (50) transmet un courant de 4 à 20 mA représentant un paramètre détecté à une boucle (52), laquelle excite l'émetteur (50). Un circuit de sortie (50) reçoit l'excitation provenant de la boucle (52) et régule la sortie de 4 à 20 mA en fonction d'une entrée de données de détecteur. Le circuit de sortie (60) produit également une sortie de commande de transformateur, laquelle sert aussi d'horloge pour le circuit isolé (106). Un circuit détecteur (82) produit une sortie de commande de transformateur représentant le paramètre détecté. Un transformateur d'isolement (76) commandé par la sortie de commande excite le circuit détecteur (82) et produit une référence d'horloge en fonction de l'oscillation de la sortie de commande jusqu'au circuit détecteur (82). Le transformateur d'isolement (76) est un dispositif à couplage unique couplant l'excitation, la référence d'horloge, des données de détecteur ainsi que des données de programmation sur une barrière d'isolement électrique située entre le circuit de sortie (50) et le circuit détecteur (82).
Patent EP-0518917-A1 (EP)
Title: Fastening devices and applicator.
Inventor: EADIE BRIAN KENNETH MACGREGOR
IPC: F16B2/24
Filed: 1991-03-01
Abstract: Fastening devices (8), particularly for use as beak bits for game birds, are generally C-shaped and include an indentation (13) which cooperates with a ridge in the interior of a magazine of an applicator device for the fastening members, and which provides other advantages. An applicator device for the fastening members is also described. <IMAGE>
Patent EP-0478755-A1 (EP)
Inventor: PETRESCU-PRAHOVA IULIAN BASARA
IPC: H01S5/10
Filed: 1991-04-04
Abstract: Diode laser à haute puissance qui est constituée par une zone d'excitation et qui possède un facteur de limitation situé entre 1,5*10-4 et 1,5*10-3 et une longueur de résonateur située entre 1,5 et 3cm, dans laquelle seul peut se propager le mode transversal fondamental possédant le maximum de la densité de flux située dans la zone principale, à cause d'une différence minime d'indice de réfraction entre les zones principale et de limitation.
Patent EP-0500831-A1 (EP)
Inventor: TORTEROTOT ROLAND
IPC: G01F11/02
Filed: 1991-07-25
Abstract: L'invention concerne un procédé de réglage des quantités de produit dosées et distribuées par un doseur-distributeur (20), le produit alimentaire ou pharmaceutique se trouvant de préférence dans un état liquide et/ou pâteux. On mesure le poids d'au moins chaque énième des récipients (101) remplis par un même doseur-distributeur (20) avec une quantité dosée du produit (102), le nombre entier n étant compris entre 1 et 1000, on compare chaque valeur de poids mesurée à une valeur étalon prédéterminée et on règle pas-à-pas et pendant le fonctionnement du doseur-distributeur (20) au moins l'une des positions extrêmes de course du piston-doseur (28) dudit doseur-distributeur (20) dans le sens d'une augmentation ou de diminution de la course du piston-doseur (28) dès que l'écart entre le poids réel mesuré et le pois étalon prédéterminé dépasse une valeur limite, et on continue ce réglage jusqu'à la disparition dudit écart.