baber/WOPTO huggingface dataset:
Patent CA-3136649-A1 (CA)
Inventor: WU YIHAO
IPC: A47L11/28
Filed: 2020-04-08
Abstract: A cleaning control method and apparatus, a cleaning robot (100) and a storage medium, relating to the technical field of intelligent devices. The method comprises the steps of: the cleaning robot (100) acquiring a map of a space to be cleaned as a first spatial map (S1); dividing, based on the first spatial map, said space into at least one cleaning region (S2); setting a cleaning sequence for the cleaning regions (S3); and performing, by taking each cleaning region as a unit, a cleaning operation on the cleaning regions of said space according to the cleaning sequence (S4). The cleaning robot (100) performs the cleaning operation on the cleaning regions of said space according to the cleaning sequence, such that the cleaned cleaning region can be prevented from being dirtied when the cleaning robot moves to a region, where a base station is positioned, for charging or for cleaning a cleaning member, thereby enhancing the cleaning effect and improving the cleaning efficiency.
Patent CA-3138984-A1 (CA)
Inventor: STOCKALL ADRIAN PETER
IPC: A24F47/00
Filed: 2020-03-31
Abstract: L'invention concerne un procédé de configuration d'un dispositif informatique personnel (104) pour une communication avec un dispositif de génération d'aérosol (102), ledit procédé entraînant une application Web progressive, PWA, (328). Une application native (326) lance un navigateur Web (324) sur le dispositif informatique personnel (104) et le navigateur Web (324) lance la PWA (328), l'application native (326) fournit une ressource au navigateur Web (324), ladite ressource amenant le navigateur Web (324) à traiter un appel reçu par le navigateur Web (324) provenant de la PWA (328) destiné au dispositif de génération d'aérosol (102) par adressage d'une commande fondée sur l'appel vers l'application native (326). La commande permet à l'application native (326) d'amener le dispositif de communication personnel (102) à communiquer avec le dispositif de génération d'aérosol (102) sur la connexion de communication sans fil à courte portée (116).
Patent CA-3139168-A1 (CA)
Inventor: JI LIANGLIANG
IPC: A61K31/485
Filed: 2019-05-07
Abstract: L'invention concerne des promédicaments d'antagonistes du récepteur opioïde tels que le nalmefène et la naltrexone, des compositions pharmaceutiques comprenant lesdits composés, et des procédés d'utilisation desdits composés pour le traitement de troubles du comportement.
Patent CA-3139464-A1 (CA)
Title: Polypeptide having antibacterial activity, composition for preventing or treating sepsis comprising same, and antibacterial composition
Inventor: PARK YEONG MIN
IPC: A61K38/00
Filed: 2020-02-27
Abstract: The present invention provides: a peptide having antibacterial activity; a composition for preventing or treating sepsis comprising same; and an antibacterial composition. More specifically, the peptide according to the present invention has the excellent effects of not only suppressing the growth of bacteria but removing endotoxins derived from bacteria, thus exhibiting an excellent therapeutic effect on sepsis, and thus can be usefully used to prevent or treat sepsis. In addition, the peptide according to the present invention has selectively excellent antibacterial activity against Gram positive/negative bacteria, and thus can be usefully used in an antibacterial composition for Gram-positive/negative bacteria, or to prevent or treat various infectious diseases caused by Gram-positive/negative bacteria. Furthermore, the peptide according to the present invention exhibits excellent resistance against proteolytic enzymes, and is highly stable, and thus is expected to be utilized in various forms, such as a pharmaceutical composition, a cosmetic composition, a food composition, a health food composition, a feed composition, and a quasi-drug composition.
Patent CA-3140499-A1 (CA)
Title: Alkaline drink
Inventor: ADAMS MICHAEL
IPC: A61K9/00
Filed: 2020-05-15
Abstract: A drink comprising in admixture stable alkaline water and a statin or a statin precursor, the pH of the water being from 8 to 10.5. The drink may include other ingredients including CBD or THC.
Patent CA-3140809-A1 (CA)
Inventor: PIGUET FRANCOISE
IPC: A61K48/00
Filed: 2020-05-20
Abstract: Rett syndrome (RTT) is a neurodevelopmental disorder that affects girls almost exclusively (about 1 in 10 000 females). It is characterized by normal early growth and development followed by a slowing of development, loss of purposeful use of the hands, distinctive hand movements, slowed brain and head growth, problems with walking, seizures, and intellectual disability. Herein, the inventors demonstrated that delivering a vector expressing a cholesterol 24-hydroxylase (CYP46A1) gene intravenously in a mouse model of RTT is able to prevent/correct the development of motor impairment, in a mild and an aggravated model of the disease both in male and female mice. In addition in males, the inventors demonstrated a prevention of the loss of Purkinje cells and an improvement of astrogliosis and microgliosis in the mild KO MECP2 model. Thus, the present invention relates to a vector for use in the treatment of Rett syndrome or related autism spectrum disorder, which vector comprises cholesterol 24-hydroxylase encoding nucleic acid.
Patent CA-3141892-A1 (CA)
Title: Devices, compositions and methods for colonic microbiome engraftment
Inventor: BORODY THOMAS JULIUS
IPC: A61P41/00
Filed: 2020-05-29
Abstract: Compositions and methods for the preparation of a subject for fecal microbiota transplantation, in particular for the removal of biofilm material from the colon of a subject, are provided. The provided compositions contain soaps, such as castile soap, and may contain biofilm-interrupting agents such as enzymes, antiparasitic agents such as nitazoxanide, secnidazole, diloxanide and/or furazolidone, as well as additional therapeutic agents. Methods for the treatment of diseases associated with microbiome dysfunction are further provided.
Patent CA-3142879-A1 (CA)
Title: Method and apparatus for removing greenhouse gases and air pollutants from the atmosphere
Inventor: THAKKAR HARSHUL
IPC: B64C39/02
Filed: 2020-05-22
Abstract: A process, an article of manufacture, and a product for efficient and cost-effective capture of greenhouse gases and air pollutants directly from the air using an unmanned vehicle including materials reclaimed from the atmosphere. The materials can be fabricated into either the actual body structure of a mobile device, into a covering or coating of the body of the mobile device or into a shape suitable for transport by the mobile device by employing any advanced technique such as (but not limited to) 3D-printing technique, laser technique and extrusion technique. The mobile device, with the incorporated materials, is deployed into the atmosphere to capture greenhouse gases and reduce atmospheric pollution in an effort to mitigate the devastating effects of global warming and unhealthy air quality.
Patent CA-3143196-A1 (CA)
Title: Acetyl-coa synthetase 2 (acss2) inhibitors and methods using same
Inventor: SCHUG ZACHARY
IPC: A61K31/4184
Filed: 2020-06-12
Abstract: The present disclosure provides compounds that are ACSS2 inhibitors. In certain embodiments, the compounds of the disclosure are useful for treating and/or preventing certain types of cancer.
Patent CA-3149711-A1 (CA)
Title: Method of and device for tracing logical node in automation testing, program and medium
Inventor: Sun Longgen
IPC: G06F11/36
Filed: 2022-02-21
Abstract: The present application relates to a method of tracing a logical node in automation testing, and corresponding device, computer equipment and storage medium. The method comprises: determining a target decision rule to be automation-tested in response to a testing instruction, wherein the target decision rule includes a plurality of logical nodes; determining execution orders to which the various logical nodes correspond, and sending logical information of the various logical nodes to a testing server end on a one-by-one basis according to the execution orders to which the various logical nodes correspond; and updating, whenever a node testing result to which any logical node of the target decision rule corresponds as returned by the testing server end is received, the execution status tracing chart to which the target decision rule corresponds as displayed in the page according to the received node testing result.
Patent CA-3150401-A1 (CA)
Inventor: FAN XIAOHU
IPC: C12N15/86
Filed: 2020-08-28
Abstract: A modified T cell comprises: i) an exogenous Negative Regulatory Factor (Nef) protein; and ii) a functional exogenous receptor comprising: (a) an extracellular ligand binding domain, (b) a transmembrane domain, and (c) an intracellular signaling domain (ISD) comprising a chimeric signaling domain (CMSD), wherein the CMSD comprises one or a plurality of Immune-receptor Tyrosine-based Activation Motifs (ITAMs), wherein the plurality of CMSD ITAMs are optionally connected by one or more linkers. Provided are also Nef proteins (e.g., non- naturally occurring Nef), and modified T cells comprising such Nef proteins. Provided are methods of making and uses thereof.
Patent CA-3151080-A1 (CA)
Title: Detection d'oscillations guidee par mesure pour la protection de moteurs
Inventor: ASHBAUGH RYAN BRIDWELL
IPC: H02P27/08
Filed: 2019-10-31
Abstract: Des moteurs à aimants permanents (PMM) peuvent développer des oscillations pendant un démarrage de moteur, lesquelles peuvent causer des dommages aux éléments constitutifs d'une pompe submersible électrique (ESP). L'invention concerne un système et un procédé d'identification d'oscillations à cause mécanique et/ou électrique dans un PMM, consistant à analyser des oscillations dans des mesures de courant et de couple. Un système de commande à l'intérieur d'un dispositif de commande de moteur de surface reçoit des mesures de courant et/ou de couple à partir de capteurs de fond de trou. Le système de commande utilise au moins un algorithme conçu pour détecter des oscillations dans les mesures. Lors de la détection d'oscillations qui sont cohérentes avec des oscillations dans le moteur à partir de causes mécaniques ou électriques, le système de commande déclenche automatiquement une action de protection pour empêcher un endommagement des éléments constitutifs d'une ESP.
Patent CA-3151450-A1 (CA)
Inventor: SCHNEIDER MATTHIAS
IPC: A61K38/00
Filed: 2020-09-30
Abstract: La présente invention concerne un liant protéique qui, lorsqu'il est lié à iRhom2 humain, se lie au moins dans une région de la boucle 1 de celui-ci.
Patent CA-3151637-A1 (CA)
Title: Methods of treating vascular diseases
Inventor: SAKURAI NAGISA
IPC: A61P11/00
Filed: 2020-08-27
Abstract: The present invention provides methods for treating vascular diseases with hemogenic endothelial cells (HEs) obtained in vitro from pluripotent stem cells. The present invention also provides compositions and methods of producing the HEs.
Patent CA-3153692-A1 (CA)
Title: Treatment of hr deficient cancer
Inventor: FUGGER KASPER
IPC: A61K38/00
Filed: 2020-09-09
Abstract: This invention relates to the finding that homologous recombination (HR) deficient cells are sensitised to PARP inhibition by either (i) catalytic inhibition or genetic ablation of 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1) or (ii) administration of a substrate of DNPH1, such as 5-hydroxymethyl-deoxyuridine (hmdU). The invention also relates to the finding that catalytic inhibition or genetic ablation of DNPH1 combined with administration of hmdU causes synthetic lethality in HR deficient cells in the absence of PARP inhibition. Methods and compounds for use in the treatment of HR deficient cancer are provided.
Patent CA-3155080-A1 (CA)
Title: Systeme de securite
Inventor: MEKURI GLEN LAAI
IPC: G08B21/02
Filed: 2020-10-16
Abstract: Système de sécurité (1) pour échafaudage sur un chantier comportant une pluralité d'éléments d'échafaudage allongés (5), reliés entre eux par une pluralité de raccords (7) pour former une structure d'échafaudage (2). Un ou plusieurs éléments reliés à une ou plusieurs semelles supportent la structure sur une surface. Au moins deux dispositifs de surveillance de la sécurité (10) sont situés à une certaine distance l'un de l'autre autour de ladite structure. Chaque dispositif de surveillance comprend une source d'alimentation, un capteur et un émetteur. Le capteur détecte un mouvement dans ladite structure et transmet un signal à un récepteur pour indiquer un mouvement dans la structure.
Patent CA-3155720-A1 (CA)
Title: Enhanced natural language processing with semantic shortcuts
Inventor: RUMIANTSAU MIKHAIL
IPC: G06F16/242
Filed: 2020-10-22
Abstract: An example embodiment may involve a software application executable on computing devices of a remote network management platform and a computation instance associated with a managed network. The computational instance may contain a database storing data of the managed network. The software application may receive, from a client device of the managed network, a natural language query (NLQ), and retrieve Backus-Naur form (BNF) rules and a set of metadata associated with the BNF rules. The metadata may include a text-based description of a schema of the database and abbreviations associated with the BNF rules. The NLQ may be parsed using the BNF rules together with the metadata by applying the metadata during parsing to extend the BNF rules. A query object based on the parsed query may be generated, and the database searched using the query object. A result of the search may be transmitted to the client device.
Patent CA-3162085-A1 (CA)
Title: Revetement de surface de support avec enveloppe sous vide et procede de fonctionnement
Inventor: DZIOBA DAVID A
IPC: A61G7/057
Filed: 2020-12-17
Abstract: L'invention concerne un revêtement de surface de support ayant des premier et second compartiments gonflables indépendamment qui est disposé à l'intérieur d'une enveloppe. De l'air peut être retiré de l'enveloppe de telle sorte que des panneaux latéraux de l'enveloppe s'affaissent contre des surfaces correspondantes du revêtement pour empêcher un mouvement latéral des panneaux par rapport aux surfaces du revêtement.
Patent CA-3162450-A1 (CA)
Inventor: SOSENKO ERIC
IPC: B62D33/04
Filed: 2020-03-25
Abstract: A tonneau system is for use with a bed of a pickup truck, the bed having opposing first and second sidewalls and also having a front sidewall extending between the first and second sidewalls at one end thereof and a rear sidewall extending between the first and second sidewalls at another end thereof. The tonneau system comprises: a tonneau cover having at least two tonneau sections including a first tonneau section and a second tonneau section, the tonneau sections being moveable relative to one another between an unfolded state and a folded state, in the unfolded state the tonneau sections substantially covering the cargo box, and in the folded state the tonneau sections being arranged in a stack with the tonneau sections arranged one atop another; and a plurality of latch assemblies, each latch assembly including a latch base and a latch handle assembly. The latch handle assembly further includes a handle, a clamp jaw, and an adjustment member, the handle and clamp jaw supported on the adjustment member with the handle being engaged with the clamp jaw and configured to move the clamp jaw relative to the adjustment member, the adjustment member being connected at one end to the latch base. The latch base includes a belt extending about end rollers and being moveable about the end rollers in a direction generally transverse to lateral side of the tonneau cover.
Patent CA-3165389-A1 (CA)
Inventor: KARELIYA ROHIT CHUNILAL
IPC: F04D25/10
Filed: 2020-10-09
Abstract: An apparatus for 360° revolving a fan includes a housing(104); a plurality of bearings (102) fixed in the housing (104); an elongate shaft (101) passing through the bearings (102) whose one end is received in a revolution control assembly (50) and other end secured with a coupling means (115); the coupling means (115) also fixedly holds downrod (134) of a fan at an angle to the elongate shaft such that the axes of downrod (134) and shaft (101) don't cross each other, creating gyroscopic structure. Power to the fan is provided through sliprings (110). When fan blades spin around fan axis, due to precession the whole fan revolves 360°.
Patent CA-3165810-A1 (CA)
Title: Method for manufacturing a multi-material part by additive manufacturing, using the technique of powder bed selective laser melting or selective laser sintering
Inventor: VERON FREDERIC
IPC: C22C1/10
Filed: 2021-01-22
Abstract: The invention relates to a process for manufacturing a multi-material part by additive manufacturing, comprising the following steps:a) a step of providing a pre-treated metal powder comprising grains and an oxidized and porous layer on a surface of said grains;b) a selective laser powder-bed fusion step comprising implementation of steps i) and ii) as follows:i) a step of forming a layer from the pre-treated metal powder;ii) a step of melting by laser said layer, said melting step being carried out under a reactive atmosphere and comprising changing parameters of application of the laser so that at least a first region of said layer is converted so as to lower the electrical conductivity thereof, thus forming a dielectric, and so that at least a second region of said layer is densified without converting it,the at least a first region being formed when the parameters of application of the laser allow a first energy density to be applied to said first region and/or the laser beam to be kept for a first dwell time on said first region, the at least a second region being formed when the parameters of application of the laser allow a second energy density to be applied to said second region and/or the laser beam to be kept for a second dwell time on said second region, and the first energy density being higher than the second energy density and/or the first dwell time being longer than the second dwell time.The invention also relates to a part obtained using said process.
Patent CA-3166631-A1 (CA)
Inventor: CAMERA PAUL N
IPC: B65B29/06
Filed: 2020-12-31
Abstract: Various techniques for generating substantially homogenous mixtures of nonpolar materials and aqueous solutions are disclosed herein. An example method includes generating a substantially homogenous mixture of an aqueous solution and a nonpolar material by flowing the aqueous solution through a porous substrate infused with the nonpolar material.
Patent CA-3167150-A1 (CA)
Inventor: GAO JINGSI
IPC: A01N25/04
Filed: 2021-01-08
Abstract: Herbicidal compositions for reducing off-site movement or drift of herbicides are described. The herbicidal compositions can include a drift retardant agent (DRA) along with at least one auxin herbicide and an emulsifying agent, such as an alkylpolysaccharide, a phosphate ester, an alkoxylated castor oil, or a combination thereof. Methods of making such composition are also described.
Patent CA-3167317-A1 (CA)
Inventor: Atwell Shane Krummen
IPC: C07K16/28
Filed: 2021-02-09
Abstract: Provided herein are methods and compositions for improving the crystallization of antibodies, antigen-binding fragments, e.g., Fab or Fab', or fusion proteins, and Fab/Fab'/mAb:Antigen complexes.
Patent CA-3169111-A1 (CA)
Title: Scelleuse d'enveloppe integree et module de retournement
Inventor: DEPOI ARTHUR H
IPC: B43M5/04
Filed: 2021-01-22
Abstract: Un système de scellement et de retournement d'enveloppe peut être intégré dans un système d'insertion de courrier pour sceller une enveloppe avec une ligne de colle continue complète et retourner simultanément la face d'enveloppe pour un traitement en aval. Le système comprend une cage de retournement qui reçoit une enveloppe et une brosse de mouillage mobile qui entre en contact avec le rabat. La cage de retournement tourne, amenant le rabat à glisser sous la brosse de mouillage, et réalignant l'enveloppe avec une ligne de contact de scellement qui scelle l'enveloppe. La cage de retorunement tourne en continu pour recevoir, retourner et sceller de nombreuses enveloppes.
Patent CA-3169307-A1 (CA)
Inventor: ZHANG MIN
IPC: A23L5/10
Filed: 2021-04-14
Abstract: La présente invention concerne un procédé d'économie d'énergie à haut rendement pour améliorer la lyophilisation de baies par prétraitement au laser en coopération avec une pulvérisation par micro-ondes. Le procédé consiste : à effectuer un traitement de perforation multipoint au laser sur des baies soumises à une pré-congélation spéciale, à effectuer une déshydratation en coopération avec une technologie de lyophilisation par pulvérisation par micro-ondes, puis, à effectuer un conditionnement.
Patent CA-3170284-A1 (CA)
Inventor: STAHL BERNHARD
IPC: B60R15/02
Filed: 2021-04-26
Abstract: The invention relates to a hot water storage system, in particular for mobile uses, comprising a water reservoir (6), a pump (10), a heat exchanger (20) and a hot water storage tank (40), characterized in that the hot water storage tank (40) has a variable reservoir volume and is provided with a drain line (60) that connects the hot water storage tank (40) to the water reservoir (6).
Patent CA-3171417-A1 (CA)
Inventor: DEL POPOLO PAOLO
IPC: B65G1/04
Filed: 2021-03-17
Abstract: La présente invention concerne un dispositif (20) de prélèvement ou de dépôt d'un article (S) à partir ou dans un compartiment (14) d'un entrepôt automatisé (50). Le dispositif (20) comporte des premiers moyens de déplacement servant à déplacer le dispositif (20) suivant une direction principale (X) à l'intérieur de l'entrepôt et des moyens principaux (28, 30) d'alimentation en énergie électrique du même dispositif. Ces derniers comportent en outre une paire de fourches (34A, 34B) déplacées, au moyen de deuxièmes moyens (35A, 36A, 35B, 36B) de déplacement, suivant au moins une direction transverse (Y) par rapport à ladite direction principale (X) entre une position rétractée et une position déployée. Chaque fourche (34A, 34B) comporte une section (343A, 343B) d'extrémité munie d'au moins un élément (50A, 51A, 52A, 50B, 51B, 52B) de poussée dudit article (S), un tel élément de poussée pouvant être déplacé entre une position de fonctionnement et au moins une position de repos. Ladite section (343A, 343B) d'extrémité comporte en outre des troisièmes moyens (54A, 55A, 56A, 54B, 55B, 56B) de déplacement servant à déplacer ledit élément de poussée. Le dispositif comporte une unité centrale (80, 80'), qui commande les parties mobiles du dispositif (20). Selon l'invention, ladite section (343A, 343B) d'extrémité comporte une unité (90A, 90B) de commande périphérique pour lesdits troisièmes moyens (54A, 55A, 56A, 54B, 55B, 56B) de déplacement; ladite unité (90A, 90B) de commande périphérique et ladite unité centrale (80, 80') de commande sont configurées pour une communication sans fil entre elles. En outre, selon l'invention, la section (343A, 343B) d'extrémité comporte en outre des rechargeables moyens secondaires (100A, 100B) d'alimentation en énergie électrique aptes à fournir une alimentation à l'unité (90A, 90B) de commande périphérique et aux troisièmes moyens (54A, 55A, 56A, 54B, 55B, 56B) de déplacement.
Patent CA-3171436-A1 (CA)
Title: Antisense sequences for treating amyotrophic lateral sclerosis
Inventor: BIFERI MARIA-GRAZIA
IPC: A61P21/00
Filed: 2021-04-09
Abstract: The present invention relates to antisense sequences, nucleic acid constructs and vectors comprising said antisense sequences, and their use for treating a C9orf72 hexanucleotide repeat expansion associated disease such as amyotrophic lateral sclerosis or frontotemporal dementia.
Patent CA-3174972-A1 (CA)
Inventor: ARORA MANSI
IPC: A61P35/00
Filed: 2021-04-07
Abstract: L'invention concerne une méthode de traitement d'une maladie ou d'un trouble, et de préférence le cancer, consistant à administrer à un sujet qui en a besoin une quantité thérapeutiquement efficace d'un inhibiteur de CDK2, et une quantité thérapeutiquement efficace d'un inhibiteur de CDK4/6, l'inhibiteur de CDK4/6 empêchant la phosphorylation de rebond médiée par CDK4 et/ou CDK6 en réponse à l'inhibition de CDK2.