baber/WOPTO huggingface dataset:
Patent EP-0999005-B1 (EP)
Inventor: WIDL GERHARD DR-ING
IPC: B23B31/28
Filed: 1999-06-08
Granted: 2003-09-03
Abstract: The clamping chuck has several clamping jaws (2) movable into an opening and holding position by a setting device which has several setting members (3) each having a medium of which one dimension can be variable controllable electrically and/or magnetically. Each setting member acts on a clamping jaw.  The setting members are associated with a control electronics (10).
Patent EP-0971126-B1 (EP)
Inventor: MORETTI GIORGIO
IPC: F04B15/02
Filed: 1999-07-08
Granted: 2006-05-03
Abstract: The invention concerns a concrete pump, of the type comprising a pair of pumping cylinders alternatively operating under the control of a backflow hydraulic pump - to draw concrete from a hopper and feed it, by way of a rocking valve (S-valve), into the transport and delivery duct - wherein said cylinders are provided with stops to control the advance of the starting movements of the S-valve and wherein the motion of the pistons in the cylinders is reversed in respect of the moment in which said pistons reach the top dead center. According to the invention, said stops are located in the position for the most efficient working with the highest number of pumping cycles per minute, and electronic means are provided to set said advance time, by delaying the starting movement of the S-valve and the reversal of the backflow hydraulic pump according to the actual number of pumping cycles per minute. <IMAGE>
Patent EP-0974620-B1 (EP)
Inventor: CATLIN JOSPEH C
IPC: C09B35/215
Filed: 1999-07-12
Granted: 2002-11-13
Abstract: A dye of formula (I) is new. M = a hydrogen ion ,an alkali metal ion or RaRbRcRdN+; RaRbRc and Rd = H, 1-6C alkyl or 1-6C hydroxyalkyl.
Patent EP-1006340-B1 (EP)
Inventor: BEIER WOLFGANG
IPC: G07B15/00
Filed: 1999-12-02
Granted: 2004-08-11
Abstract: The method involves providing the course of the streets in the vehicle as a data set and at least two separate setting algorithms. The algorithms are used to combine movement-related data, especially the distance from an exit position, vehicle rotation and position data obtained using a global positioning system, with the data set of street characteristics. The algorithms extend from an exit position, especially from a reference point (3') based on three measurement co-efficients. One co-efficient relates an East-West distance obtained from geographical latitude co-ordinates in proportion to an odometer determined distance between the current position and the exit position. One co-efficient relates a North-South distance obtained from geographical latitude co-ordinates in proportion to the odometer determined distance between the current position and the exit position. One co-efficient relates to a gyrometrically determined vehicle rotation, especially between the exit and current positions, in proportion to the odometer determined distance between the current position and the exit position. An Independent claim is included for a system for implementing the method.
Patent EP-0992781-B1 (EP)
Inventor: DYER STEPHEN WILLIAM
IPC: G01M1/22
Filed: 1999-10-08
Granted: 2005-03-16
Abstract: A tool holder assembly 10 including a tool holder 12 having a balancer assembly 21 adapted to selectively provide improved unbalance compensation. <IMAGE>
Patent EP-1053276-B1 (EP)
Title: Melanges de polymeres ameliores pour deshydratation
Inventor: FARINATO RAYMOND SALVATORE
IPC: C08J3/09
Filed: 1999-01-12
Granted: 2007-03-14
Abstract: L'invention porte sur des mélanges à poids moléculaire élevé, sur des polymères structurés, cationiques, solubles dans l'eau à poids moléculaire élevé, sur des polymères cationiques solubles dans l'eau qui sont linéaires ou qui ont un degré inférieur de structure. Les mélanges sont utilisés pour déshydrater des dispersions de solides en suspension, et obtenir de bons taux de déshydratation à des niveaux de dosage relativement bas.
Patent EP-0990631-B1 (EP)
Inventor: ISHII YASUTAKA
IPC: B01J31/02
Filed: 1999-03-23
Granted: 2007-01-24
Abstract: Procédé permettant de co-oxyder des composés organiques, qui consiste, en présence d'un composé imide tel que le N-hydroxyphtalimide, à oxyder par l'oxygène moléculaire un composé (A), choisi entre (A1) des composés renfermant une liaison éthylénique non aromatique et (A2) des cétones ou des alcools correspondant auxdites cétones, et un composé (B), pouvant être oxydé par le composé imide ci-dessus avec l'oxygène et différent dudit composé (A). Comme composé (B), on peut utiliser (a) des alcools primaires ou secondaires (benzhydrol, cyclohexanol, etc.) ou (b) des composés renfermant une liaison carbone-hydrogène adjacente à une liaison insaturée (Tétraline, éthylbenzène, etc.). Ce procédé permet d'obtenir avec un bon rendement les composé époxy correspondants à partir des composés (A1) renfermant une liaison éthylénique non aromatique, et les esters ou les lactones correspondants à partir (A2) des cétones ou des alcools correspondant auxdites cétones.
Patent EP-1093467-B1 (EP)
Inventor: VAN DER LUGT JAN PIETER
IPC: C07C51/285
Filed: 1999-05-04
Granted: 2002-03-27
Abstract: Primary alcohols, especially in carbohydrates, can be selectively oxidized to aldehydes and carboxylic acids in a low-halogen process by using a peracid in the presence of a catalytic amount of a di-tertiary-alkyl nitroxyl (TEMPO) and a catalytic amount of halide. The halide is preferably bromide and the process can be carried out at nearly neutral to moderately alkaline pH (5-11). The peracid can be produced or regenerated by means of hydrogen peroxide or oxygen. The process is advantageous for producing uronic acids and for introducing aldehyde groups which are suitable for crosslinking and derivatization.
Patent EP-1087183-B1 (EP)
Inventor: NAKAMURA JYUNJI
IPC: F24F1/0073
Filed: 1999-05-26
Granted: 2005-10-12
Abstract: L'invention concerne une unité de conditionnement d'air prévue pour être placée à l'intérieur. Cette unité est conçue de telle sorte que l'entrée d'air supérieure de son carter et la partie adjacente à cette entrée peuvent être nettoyées aisément. Cette unité comprend une entrée d'air avant (4) ménagée dans l'avant du carter (1), une entrée d'air supérieure (6) ménagée dans le sommet du carter (1) et un panneau formant grille supérieure amovible (7) pouvant coulisser d'avant en arrière par rapport au carter (1) et recouvrant l'entrée d'air supérieure (6). Pour nettoyer l'entrée d'air supérieure (6) et sa partie adjacente, la personne chargée du nettoyage détache le panneau formant grille supérieure (7) de la grille avant (3) et peut ainsi les nettoyer et les laver à l'eau si nécessaire, dans une position garantissant toute sécurité, tout en assurant que les parties sales sont rapidement nettoyées.
Patent EP-1099345-B1 (EP)
Inventor: DEWEESE TOBY
IPC: H04N7/16
Filed: 1999-08-26
Granted: 2002-10-16
Abstract: A television chat system is provided that allows television viewers to engage in real-time communications in chat groups with other television viewers while watching television. Users of the television chat system may engage in real-time communications with others users who are currently watching the same television program or channel. The system allows real-time communications in a chat group to be transmitted between users at user television equipment devices via a television distribution facility. The television chat system of the present invention permits users to join chat groups related to television programs, channels, or categories of programs that the user may be interested in. Real-time communications may be textual messages, audio communications, or video communications. The television chat system may also allow users to send chat requests to ask other users to enter a chat group. The system also permits users to establish chat groups that television viewers are permitted to join. The television chat system may be based on an interactive television program guide or set-top box application implemented on a set-top box.
Patent EP-1088143-B1 (EP)
Inventor: BRETON JACQUES PAUL
IPC: E05B37/16
Filed: 1999-06-18
Granted: 2003-03-19
Abstract: The invention concerns a mechanism for authorising a control member movement by forming a code, comprising a body (20), several stop elements (24) each arranged in a hole of the body (20), an elongated slide (28) sliding in a sliding space and having a series of cuts along each of its lateral edges, push-buttons (14) for moving a corresponding stop element and bearing different signs displayed outside the mechanism such that the sequential control corresponds to a series of signs forming a code, a return tilting plate, and a linking device for transforming a control member movement into a movement translating the slide (28). The invention is applicable to locks.
Patent EP-1137420-B1 (EP)
Inventor: GORNY PHILIPPE
IPC: A61K33/00
Filed: 1999-12-02
Granted: 2007-04-04
Abstract: Abstract of Disclosure A method for using, in combination, a purine and a nitric oxide donor as active ingredients in the preparation of a drug for preventing or treating disorders of physiological and/or anatomical response to sexual stimulation in human beings.
Patent EP-1142377-B1 (EP)
Inventor: BONTA JEFFREY D
IPC: H04W36/30
Filed: 1999-12-13
Granted: 2005-06-15
Abstract: L'invention porte sur un procédé déterminant si l'on doit ou non opérer un transfert dans un système de télécommunications sans fils (100). Le système (100) recueille de premières variables environnementales concernant une première station mobile du système (100) puis détermine quand une communication entre une station (101) de base et la première station mobile est indûment interrompue, puis analyse les premières variables environnementales pour élaborer des règles relatives à l'état de l'environnement, puis enfin applique lesdites règles à une deuxième station mobile qui communique alors avec la station de base (101) et dont les variables environnementales sont sensiblement similaires aux premières variables environnementales.
Patent EP-1135170-B1 (EP)
Inventor: ZALUTSKY MICHAEL R
IPC: A61K49/00
Filed: 1999-11-30
Granted: 2006-10-25
Abstract: Antibodies to cell surface ligands such as EGFRvIII can be used to therapeutically or diagnostically deliver a radiolabel to tumor cells with high selectivity. The utility of radioconjugated internalizing antibodies is limited, however, by release of the label and its reuptake into normal cells. The invention provides new technology for radioconjugation of internalizing antibodies which reduces the release of label and improves retention of radioconjugated antibodies in lysosomes, where radiation is more effectively and selectively delivered to the nucleus of tumor cells.
Patent EP-1161302-B1 (EP)
Inventor: BEHNSEN PETER
IPC: B29B17/02
Filed: 1999-05-19
Granted: 2004-02-18
Abstract: The invention relates to an installation and method for separating substance mixtures containing constituents which have different densities using a liquid separating medium in which light fractions rise and heavy fractions sink. The invention is characterized in that a first and a second guiding plate (4, 5) are provided in a separating container (1). Said guiding plates are horizontally arranged, accommodate cones (6, 7) between them, and form a flow chamber which is provided for the exiting mixture and which is pointed laterally outward. The invention is also characterized by a device for selectively controlling the quantity of the mixture which consists of heavy fractions and of a separating medium and which is withdrawn per unit of time through the lower outlet line (12).
Patent IT-1264663-B1 (IT)
Title: Ternary quasi-azeotropic mixtures and their use as propellant fluids for aerosols and spray insulating foams
Inventor: BASILE GIAMPIERO
IPC: C07C/
Filed: 1993-07-05
Granted: 1996-10-04
Abstract: Ternary mixtures comprising: a) CF3-CH2F (HFC-134a), or CF3-CF2 (HFC-125), b) n-butane and/or isobutane, or dimethyl ether, c) one hydro(chloro)fluorocarbon selected from: CF3-CF2 (HFC-125), CH2F2 (HFC-32), CF3-CH3 (HFC-143a), CClF2-CH3 (HFC-142b), CClF2-CH3 (HFC 152a), having quasi-azeotropic behaviour, high solvent capacity and low flammability are used as propellant fluids for aerosols and spray insulating foams.
Patent IT-1312042-B1 (IT)
Inventor: TESTA RENATO
IPC: B42F7/02
Filed: 1999-03-31
Granted: 2002-04-04
Abstract: The envelope (10) comprises one or more pockets (11) for holding flat articles (12); close to at least one side edge the pocket (11) comprises an intermediate welding line (19, 19', 19'', 19''') provided with clamping means (20, 20', 20'') for frictionally retaining an article (12), by stretching the pocket between side welds; guide means (19, 19', 19'', 19''') in the form of a slanted welding are provided on at least one side of the pocket (11) to guide the article (12) from the open side of the same pocket towards the article clamping means (20, 20', 20''). <IMAGE>
Patent IT-1265546-B1 (IT)
Title: Filling machine, for food products in particular
Inventor: DORDONI GIANNI
IPC: B65B/
Filed: 1993-11-25
Granted: 1996-11-22
Abstract: This invention concerns a filling machine, for food products in particular. A conveyor belt 6, provided with a plurality of apertures 7, is placed between the outlet of a product filling hopper 4 and the containers to fill in transit on a conveyor line 1, in such a way that each aperture, passing through the filling zone, moves while being maintained compressed within the vertical of the mouth of a container. <IMAGE>
Patent IT-1296413-B1 (IT)
Title: Grasping element for containers made of plastic and the grasping procedure
Inventor: BELLI GIUSEPPE
IPC: B67C/
Filed: 1997-11-13
Granted: 1999-06-25
Abstract: This invention is used in the field of treatment of containers systems. This invention refers to a grasping element (2) attached to a rotating machine (1) through at least one flexible connector (6) shaped in such a way to free the gripping element by moving it at an angle in respect to the rotating machine (1) that it is attached to. The gripping element (2) should be made of steel and the connectors (6) should be of flexible rubber. Corresponding to the entrance and exit phases of the containers (5) into the machine (1) the procedure provides for an angular of the gripping elements relative to the rotating machine so as to accompany the containers during their transfer back to and from the machine.<IMAGE>
Patent IT-1308560-B1 (IT)
Title: Corkscrew for removing cork stoppers from bottles has hollow housing containing sliding rod with pointed worm on its end that is moved by rotating levers attached to circular discs on side of housing
Inventor: FERRARI RUGGERO
IPC: B67B/
Filed: 1999-09-09
Granted: 2002-01-08
Abstract: The corkscrew has a housing (3) with an end (105) that fits on the bottle's neck. The housing contains a sliding rod (9) with a helical worm (4) at its end. Two circular discs (14) are pivotally mounted (15) on the upper housing (3b). When levers rotate the discs, a cam (17) acting on pin (11) causes the sliding rod to move inside the housing and the worm rotates by interaction with a guide (26).
Patent IT-1289802-B1 (IT)
Title: Automatic tape splicing unit and tape splicing method - for food packaging machine of fluidity or semi-fluidity
Inventor: KRAFT PETER
IPC: B65B/
Filed: 1996-12-24
Granted: 1998-10-16
Abstract: The automatic splicing unit has an abutment block and a heating block movable in relation to each other into abutment engagement for applying heat and pressure to mutually overlapping portions of first and second thermoplastic tapes for welding the first and second tapes together at a welding plane. A cutter is connected to the heating block and is movable into the welding plane for cutting through the first thermoplastic tape. A tape displacement member is connected to the heating block for displacing the second thermoplastic tape away from the welding plane simultaneously with the movement of the cutter. A method for splicing tapes with the device is also disclosed.
Patent IT-1267238-B1 (IT)
Title: Device to mix liquid substances with particles having different granule sizes and relative mixing method
Inventor: PALADIN ROMEO
IPC: B01F7/04
Filed: 1994-05-13
Granted: 1997-01-28
Abstract: A device to mix liquids with particles having different granule sizes comprises a mixing chamber (13) and includes a feeder inlet (11), a main outlet (14), injectors (15) to inject an adhesive mixt. and possible agitation elements. The mixing chamber cooperates with rotary feeder thrust means (112), the mixing chamber including at least one screening extractor outlet (20) associated with riddle means (30) to screen the granule size of particles. The at least one screening extractor outlet covers a zone which runs from the beginning of the feeder inlet of the mixing chamber to the vicinity of the first upstream injector injecting the adhesive mixt. The screening extractor outlet affects the perimetric periphery of the mixing chamber by at least 5% of the perimeter of the mixing chamber. The screening extractor outlet cooperates with at least one channel (24) to convey the fine particles thus sepd.
Patent JP-S5033520-B1 (JP)
IPC: C10N30/04
Filed: 1969-12-20
Abstract: 1286966 Nitrogen containing esters of carboxycopolymers LUBRIZOL CORP 18 Dec 1969 [20 Dec 1968 20 Oct 1969] 61743/69 Heading C3P [Also in Division C5] A nitrogen-containing mixed ester of a carboxy-containing interpolymer is claimed, the interpolymer having a reduced specific viscosity of from 0À05 to 2, and the ester being free of titratable acidity and having within its polymeric structure at least one of each of three pendant polar groups: (A) A relatively high molecular weight carboxylic ester radical having at least 8 aliphatic carbon atoms, (B) A relatively low molecular weight carboxylic ester radical having no more than 7 aliphatic carbon atoms, and (C) A carbonyl-polyamino group derived from a polyamino compound including a primary or secondary amino group, the molar ratio of (A) : (B) : (C) being (60-90) : (10-30) : (2- 15). The interpolymer may be a styrene-maleic anhydride interpolymer. The ester may be made by (1) partially esterifying a styrenemaleic anhydride interpolymer having a reduced specific viscosity of from 0À05 to 2 with a mixture of a relatively high molecular weight alcohol having at least 7 aliphatic carbon atoms, and a relatively low molecular weight alcohol having no more than 6 aliphatic carbon atoms, so as to convert from 50 to 98% of the carboxy radicals of the interpolymer to ester radicals, the molar ratio of the relatively high molecular weight alcohol to the relatively low molecular weight alcohol being from 2 : 1 to 9 : 1, and (2) neutralizing the remaining carboxy radicals of the interpolymer with a polyamino compound including a primary or secondary amino group e.g. aminopropyl morpholine, N-aminoethyl and 1-methyl-4-aminoethyl piperazine, dimethylamino-ethylamine, dibutylamino-propylamine, N-aminoethyl pyrrole, N-aminopropyl thiopyrrolidone, N-aminoethyl caprolactam, N- aminophenyl oxazolidone, 4-aminoethyl thiazole, 2-cyclohexyl triazine, 1-aminoethyl-2- hepta-decylimidazoline, N-aminooctyl succinamide 3-aminobvtyl nracil, 4-aminobutyl pyridine or N-aminomethyl phenolthiazine. The ester may be compounded with a lubricating oil.
Patent JP-2955555-B1 (JP)
Title: ネットワークシステム
IPC: H04B10/27
Filed: 1998-04-23
Granted: 1999-10-04
Abstract: 【要約】
【課題】単独ノードあるいはループ接続されたノード群 がひとつの光スターカプラによる物理的共通媒体に複数 接続したループ及びバス混在のネットワークシステムを 構築する。
【解決手段】図１に示すように、光スターカプラにルー プが接続された混在接続とする。各ノードはノード固有 のＩＤを持ち、ＩＤにはループ毎に固有のループアドレ スとループ上で固有のノードアドレスを含む。ループ上 の伝送路は一方向にのみパケット伝送可能で、パケット は光スターカプラあるいはループを経由して、ＬＡＮ上 の全ノードに伝送される。前記構成のＬＡＮにおいて、 光スターカプラに直接パケットを出力するノード( ルー プマスタ) がパケットの破棄、あるいはバスへの出力を 制御することにより、光スターカプラによるバス接続と ループ接続の混在接続を可能とする。
Patent JP-3025886-B1 (JP)
Title: コネクタのロック解除機構
IPC: H01R13/633
Filed: 1999-05-21
Granted: 2000-03-27
Abstract: 【要約】
【課題】  コネクタのロック解除機構で、ハウジングに 対するコネクタのロック解除と引き抜きを一動作により 簡便にする。
【解決手段】  コネクタ２をハウジング１内に先端の傾 斜面７で案内させつつ押し込むことで、前記ハウジング １の側壁１ｃ内面に設けた係止突部と係止してコネクタ ２がロックされるよう当該コネクタ２の外側部に、コネ クタ２側面と離間することでバネ性を与えて軸方向に突 設したロック爪６を設けると共に該ロック爪６の表面中 央部に傾斜凹部６ｃを、先端内側から後方外側へ傾斜上 昇して形成し、他方、前記ロック爪６上に軸方向へスラ イド自在にスライドバー８を配置して、その先端下部に 形成した突設部８ａを前記ロック爪６の傾斜凹部６ｃに 嵌合して構成する。
Patent JP-2967776-B1 (JP)
Title: 機構部制御方法および装置
IPC: G05B15/02
Filed: 1998-06-04
Granted: 1999-10-25
Abstract: 【要約】
【課題】  対象物の種類に対応して機構部の動作手順を 簡単に変更可能とする。
【解決手段】ホストＰＣ１では、記憶手段１３にユニッ ト制御プログラムを機種別に予め記憶しおき、機種切り 替え手段１２が入力手段１１により入力された機種に対 応したユニット制御プログラムを記憶手段１３から読み 出し、通信手段１４を介して送信する。登録手段１５ は、制御ユニット２から通信手段１４を介して受信した 機種別のユニット制御プログラムを記憶手段１３に記憶 させる。制御ユニット２では、通信手段２１によりホス トＰＣ１から受信したユニット制御プログラムを記憶手 段２２にする。制御実行手段２３は、記憶手段２２に記 憶されたユニット制御プログラムを実行し機構部の動作 を制御する。入力手段２４を使用して新たなユニット制 御プログラムを記憶手段２２に書き込み、通信手段２１ を介してホストＰＣ１へ送出する。
Patent JP-3038383-B1 (JP)
Title: 光デバイス
IPC: G02F1/025
Filed: 1999-06-08
Granted: 2000-05-08
Abstract: 【要約】
【課題】  大きな消光比が得られると共にディジタル的 に動作するのに好適な光デバイスを実現する。
【解決手段】  導波路構造体の両側に第１及び第２の電 極（７，８）を形成し、これら電極により導波路構造体 にキャリァ注入領域（３ａ）及びこれに隣接する非キャ リァ注入領域（３ｂ）を形成する。キャリァ注入領域 （３ａ）に大量のキャリァが蓄積されると、この領域の 屈折率は隣接する非キャリァ注入領域の屈折率よりも相 対的に低下する。この状態において、エネルギーレベル の低い光波が入射してもこの光波により消費されるキャ リァ量は少ないため、この領域の屈折率は依然として非 キャリァ注入領域の屈折率よりも低い状態に維持され、 入射した信号光は外部に放射する。一方、エネルギーレ ベルの高い光波が伝搬すると、この光波により消費され るキャリァ量が増大し、この領域（３ａ）の屈折率は非 キャリァ注入領域（３ｂ）の屈折率よりも相対的に高く なり、入射面から出射面に至る光誘導導波路が形成され る。この結果、ガイディング効果と光増幅効果の相乗効 果により光増幅された信号光を出射させることができ る。
Patent JP-2839026-B1 (JP)
Title: 並列画像処理装置
IPC: G06F15/177
Filed: 1997-06-25
Granted: 1998-12-16
Abstract: 【要約】
【課題】  １次元結合の分散メモリ型プロセッサアレイ に基づく並列画像処理装置上で、多数点から並列に、そ の８近傍方向へ値を伝搬する並列伝搬処理を高速化す る。
【解決手段】  隣接ＰＥから直接読むことが可能な伝搬 処理用のレジスタＰを設け、その中に並列伝搬処理にお ける隣接ＰＥからの情報、すなわち伝搬の有無を格納す るフィールドＤ１〜Ｄ８、そして伝搬有の場合はさらに 伝搬値を格納するフィールドＶおよび伝搬位置を格納す るフィールドＹを設けることで、全ＰＥが直接かつ同時 に自らの隣接ＰＥから伝搬に係わる情報を得ることを可 能にする。
Patent JP-2997244-B1 (JP)
Title: ポリイソシアネート化合物及びその製造方法
IPC: C07C323/25
Filed: 1998-07-29
Granted: 2000-01-11
Abstract: 【要約】
【課題】  高屈折率、低分散で、光学特性に優れる光学 材料の原料として有用な新規なポリイソシアネート化合 物、および、このものを効率よく製造する方法を提供す る。
【解決手段】  一般式（Ｉ）
【化１】
 （ｎは１〜４の整数を示す。）で表されるポリイソシア ネート化合物、および１，２，３−トリメルカプトプロ パンと末端にハロゲン原子またはビニル基を有する脂肪 族カルボン酸低級アルキルエステル、あるいは１，２， ３−トリハロゲノプロパンと末端にメルカプト基を有す る脂肪族カルボン酸低級アルキルエステルを用い、トリ カルボン酸エステル体、トリカルボニルヒドラジド体を 経て、目的のポリイソシアネート化合物を製造する方法 である。
Patent NO-317991-B1 (NO)
Inventor: GUILLAUMET GERALD
IPC: A61P25/00
Filed: 2000-12-01
Abstract: 1,4-Benzoxazine and 1,4-benzothiazine compounds (I) and their acid or base addition salts, enantiomers and diastereomers, are new. 1,4-Benzoxazine and 1,4-benzothiazine compounds of formula (I) and their acid or base addition salts, enantiomers and diastereomers, are new. R1 = R, OR, SR, SO2NRR', NRR', -N(R)C(=Z)R', -N(R)SO2R', -N(R)C(=Z)OR', -N(R)C(=Z)NR'R'', C(=Z)OR, -OC(=Z)R or -C(=Z)NRR'; Z = S or O; R, R', R'' = H or 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 3-8C cycloalkyl or 3-8C cycloalkyl-1-6C alkyl (all optionally substituted by one or more B), or aryl, aryl-1-6C alkyl, heteroaryl or heteroaryl-1-6C alkyl (all optionally substituted by one or more D; or NRR' or NR'R'' = morpholinyl, piperidinyl, piperazinyl or pyrrolidinyl; G = 1-4C alkylene (optionally substituted by R, OR, COR or COOR; A = -C(=Z)NRR', -N(R)C(=Z)R' or -N(R)C(=Z)NR'R''; R2 = halo, R, OR, COR, COOR or OCOR; X = O or S; dotted line = single or double bond; B = OH, alkoxy, alkyl, polyhaloalkyl, NH2, NH(1-6C alkyl), N(1-6C alkyl)2 or halo; D = OH, alkoxy, amino, alkylamino, dialkylamino, nitro, cyano, polyhaloalkyl, formyl, carboxyl, alkoxycarbonyl, amido or halo; aryl = phenyl, naphthyl or biphenyl; and heteroaryl = mono- or bicyclic aromatic group containing 1-3 O, S or N; provided that when A = -C(=Z)NRR', G = 2-4C alkylene.
Patent NO-328150-B1 (NO)
Inventor: GABETTA BRUNO
IPC: C07D493/00
Filed: 2002-01-03
Abstract: The invention discloses an oxazolidine intermediate for the synthesis of 14- beta -hydroxy-1,14-carbonate-baccatines bearing a 13-isoserine substituent, and a process for the preparation thereof.