baber/WOPTO huggingface dataset:
Patent AU-2218392-A (AU)
Title: Diastereomers of 1-(isopropoxycarbonyloxy)ethyl 3-cephem-4-carboxylate and processes for their preparation
Inventor: FISCHER GERD
IPC: C07D501/34
Filed: 1992-09-08
Abstract: Enterally absorbable diastereomers of (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(m ethoxymethyl)-3-cephem-4-carboxylic acid 1-(isopropoxycarbonyloxy)ethyl ester of the formula I <IMAGE> and its physiologically acceptable salts and also diastereomerically pure salts of the compounds of the general formula II <IMAGE> where HX represents a mono- or polybasic acid and where X represents an inorganic or organic physiologically acceptable anion, and a process for the preparation of these compounds of the formula I or II are described, which is characterised in that on mixing together one equivalent of a solution of the diastereomer mixture of the formula III with 0.2 - 2 equivalents of a solution of the acid component HY the more poorly soluble diastereomer of the general formula IV is first precipitated and separated off by filtration, then the more readily soluble diastereomer of the general formula IV is precipitated from the filtration solution, it being possible in the subsequent subsidiary steps for the acid components HY to be identical or different and any desired sequence of the addition of different acid components HY to be used, and the salts obtained are optionally further purified by crystallisation.
Patent AU-2219392-A (AU)
Title: Polysiloxanic stabilizers containing sterically hindered phenol groups and reactive groups
Inventor: PALLINI LUCIANO
IPC: C08L83/06
Filed: 1992-09-08
Abstract: Polymeric stabilizers with a polysiloxanic structure contain sterically hindered phenol groups and reactive groups capable of binding themselves to the polymeric structure to be stabilized. These polymeric stabilizers are particularly suitable for applications which require the non-extractability of additives due to solvents, fats or soaps.
Patent AU-2313395-A (AU)
Title: Piezoelectric sensors
Inventor: CASSELDEN IAN
IPC: G01F23/22
Filed: 1995-04-25
Abstract: PCT No. PCT/GB95/00939 Sec. 371 Date Oct. 25, 1996 Sec. 102(e) Date Oct. 25, 1996 PCT Filed Apr. 25, 1995 PCT Pub. No. WO95/29389 PCT Pub. Date Nov. 2, 1995A piezoelectric sensor probe comprises an elongate insulative support member supporting a plurality of piezoelectric sensing elements spaced along the length of the member, the support member has respective conductors extending from one end of the member to each of the sensing elements for conducting electrical signals to and from each sensing element.
Patent AU-2375695-A (AU)
Title: Solid-phase filtration method for antigen and antibody assays in bloodgroup serology, and test kit
Inventor: BOER PIETER JOHANNES DEN
IPC: G01N33/80
Filed: 1995-05-09
Abstract: Assay in a sample of a bloodgroup antigen present on erythrocytes or an antibody binding to such a bloodgroup antigen. The sample is treated with a reagent containing antibody binding to a bloodgroup antigen, or erythrocytes, whereby a complex of erythrocyte, bloodgroup antigen present thereon and antibody bound thereto is formed if the reagent contains antibody binding to a bloodgroup antigen present in the sample or the sample contains antibody binding to a bloodgroup antigen present in the reagent. This complex, if any has formed, is separated from uncomplexed erythrocytes by filtration through a solid phase which is permeable to the uncomplexed erythrocytes, on which phase an immunoglobulin-binding material is immobilized, whereafter the result is detected. The filtration can be effected by means of centrifugation. The method can be used for bloodgroup assay, antibody screening and identification, and cross tests.
Patent AU-2427288-A (AU)
Title: Biological materials, processes for producing biological materials and for using such materials in therapy
Inventor: DAYER JEAN-MICHEL
IPC: C07K14/00
Filed: 1988-08-17
Abstract: This invention relates to interleukin 1 inhibitors (IL-1 INHs) that selectively inhibit interleukin 1 activity. The invention also relates to processes for purifying such IL-1 INHs from urine and for producing such IL-1 INHs by hosts transformed with recombinant DNA molecules comprising DNA sequences encoding the inhibitors, and to methods of treatment and compositions characterized by such IL-1 INHs. These methods and agents are useful in immunosuppressive and anti-inflammatory applications and therapies.
Patent AU-2449701-A (AU)
Title: Methods and systems for routing messages in a communications network
Inventor: MCCANN THOMAS MATTHEW
IPC: H04W88/18
Filed: 2000-12-22
Abstract: A flexible routing node for re-directing signaling messages in a communications network is disclosed. Re-direction or re-routing of signaling message packets is accomplished through the use of a range or block-based database in conjunction with an exception-based database. The range-based routing instruction databases incorporates a data structure that maps ranges or blocks of mobile identification numbers (MINs) to a single destination network address, while the exceptions database stores any exceptions to these range or block-based rules. The pair of routing databases is implemented such that, when a signaling message is received that requires re-direction, the exception-based database is queried first. If a match is found in the exceptions database, the signaling message is modified using the returned routing instructions and transmitted into an associated communication network. If no match is found in the exception-based database, a default query is performed against the range-based database. The signaling message is then modified using the routing instructions returned by the range-based database and transmitted into an associated communication network.
Patent AU-2456495-A (AU)
Title: Method and apparatus for the biochemical purification of a liquid medium
Inventor: MAEHL DIETER
IPC: C02F3/00
Filed: 1995-05-24
Abstract: PCT No. PCT/NL95/00183 Sec. 371 Date Nov. 13, 1996 Sec. 102(e) Date Nov. 13, 1996 PCT Filed May 24, 1995 PCT Pub. No. WO95/32923 PCT Pub. Date Dec. 7, 1995A method and apparatus for the biochemical purification of a contaminated liquid medium, in which the liquid medium is passed through granular filter material provided in a holder and in which the granular filter material (12) contained in the holder is set in motion, preferably with the aid of an injected gas such as air. Microorganisms and/or an active water for microorganisms can be added to the holder. The filter material may comprise a mixture of lava and sand, for example 28% to 38% sand and 61% to 71% lava. The granule size of the sand is 0.3 to 1.2 mm and the granule size of the lava is 2 to 10 mm. The main flow of the medium to be purified and the injected gas are oppositely directed. To set the filter material in motion, use is made of an inner tube (33) placed in an outer tube (32), gas being blown through the inner tube under the lower end of the inner tube (31) so that gas and filter material drawn in at the lower end of the tubes and medium are transported upward through the inner tube.
Patent AU-2538199-A (AU)
Title: Treating cancer
Inventor: WARENIUS HILMAR MEEK
IPC: C07K14/47
Filed: 1999-02-18
Abstract: Provided is a method for the diagnosis of a cancerous or pre-cancerous state in a subject, comprising testing a sample comprising cells or an extract therefrom for the co-elevation of CDK1 and CDK4. Also provided is a kit for the diagnosis of a cancerous or pre-cancerous state in a subject, comprising: (i) a means for testing for the elevation of CDK1; and (ii) a means for testing for the elevation of CDK4.
Patent AU-2654997-A (AU)
Title: Method for guiding the beating in a refiner and arrangement for performing the method
Inventor: KARLSTROM ANDERS
IPC: D21D1/20
Filed: 1997-04-07
Abstract: PCT No. PCT/SE97/00577 Sec. 371 Date Oct. 15, 1998 Sec. 102(e) Date Oct. 15, 1998 PCT Filed Apr. 7, 1997 PCT Pub. No. WO97/38792 PCT Pub. Date Oct. 23, 1997Methods and apparatus are disclosed for controlling the beating of fibrous material to be treated in a refiner. The method includes measuring a property of the fibrous material treated in the refiner, measuring the temperature or pressure in the beating zone between the refiner disks, and altering the temperature in the beating zone based upon the measured property of the fibrous material treated in the refiner. The apparatus disclosed includes pressure and temperature gauges for measuring the pressure and temperature in the beating zone, gauges for measuring the property of the fibrous material treated in the refiner, a computer to compare the measured values of the temperature or pressure with desired values for these parameters, and a controller for altering the temperature in the beating zone based upon the measured value of the property of the fibrous material treated in the refiner.
Patent AU-2664795-A (AU)
Title: Device and installation for use in the processing of cellulose solutions
Inventor: ZIKELI STEFAN ING
IPC: B29C48/475
Filed: 1995-06-26
Abstract: A device for controlling pressure in a flowing viscous mass includes an inlet, a guiding element having a receiving capacity for the mass flowing from the inlet, a piston movable within the guiding element, and a receptacle which telescopically slides over the inlet when the piston moves.
Patent AU-2714888-A (AU)
Title: Air conditioner dryer utilizing water-absorbing polymers
Inventor: FREEMAN CLARENCE S
IPC: F25B43/00
Filed: 1988-10-14
Abstract: Containment means in the form of water-absorbing polymers are included in the path of a refrigeration cycle to remove accumulated water or water vapor that inherently develops. Such polymers do not lose their efficiency even when they become oil coated, which occurs because lubricating oil is normally circulated with the refrigerant and refrigerants like freon are also somewhat oily. Preferably such containment means are in the form of polymer granules included in a bag or sack placed in a readily-openable canister, which itself is placed inside the housing of a dehydrator. This dehydrator housing also has a readily opened lid held on by a quick-disconnecting clamping means.
Patent AU-2719099-A (AU)
Title: Multipurpose antibody derivatives
Inventor: SCHOONJANS REINHILDE
IPC: A61K38/00
Filed: 1999-01-25
Abstract: The present invention relates to a class of molecules specified as novel multipurpose antibody derivatives. This class of molecules is created by heterodimerization of two constituting components. Heterodimerization is obtained by the specific heterotypic interaction of a chosen VH-CH1 combination of immunoglobulin domains, with a chosen VL-CL combination of immunoglobulin domains. The appropriate VH and VL domains in the VHCH1 and VLCL context, a binding specificity can be constitituted by the heterodimerization scaffold itself. One or both of the comprising VHCH1 and VLCL chains can thus be extended at either the N- or the C-terminus or both with other molecules, such as a toxin polypeptide, an enzyme, a hormone, a cytokine, a signaling molecule, or a single chain linked Fv fragment with the same or a different specificity.
Patent AU-2723384-A (AU)
Title: Production of human insulin-like growth factor through biogenetic techniques
Inventor: BARR PHILIP J
IPC: C12N15/16
Filed: 1984-04-24
Abstract: Prodn. of human insulin-like growth factor (IGF) comprises growing host cells contg. a structural gene which comprises a functional DNA construct of the gene encoding IGF joined in proper reading frame with secretory leader and processing signal sequences recognised by the host, and isolating secreted human IGF. The structural gene is downstream from and under transcriptional regulatory control of a transcriptional initiation region in a vector compatible with the host. The host is pref. a yeast. A DNA construct comprising a coding sequence for human IGF under transcriptional regulation of regulatory signals utilised by yeast is new. Also claimed is a construct contg. the IGF gene for expression in a cultured cellular host. Nucleotide sequences are defined with corresp. aminoacid sequence.
Patent AU-2869800-A (AU)
Title: Communication protocol between a communication device and an external accessory
Inventor: CHANG CHIENCHUNG
IPC: H04M1/72409
Filed: 2000-02-04
Abstract: A method and apparatus for communicating both voice and control data between a communication device (such as a cellular phone) and an external accessory (such as a hands-free kit) over a data bus. The method includes formatting a sequence of bits into a repeating sequence of first time slots and second time slots, transmitting the voice data in the first time slot, and transmitting the control data in the second time slot. Notably, a first bit of each of the second time slots comprises a clock bit that alternates between a high value and a low value (e.g. a "1' or a "0') as between consecutive second time slots.
Patent AU-2884799-A (AU)
Title: Radial granulator and method
Inventor: MAGUIRE STEPHEN B
IPC: B29B9/00
Filed: 1999-02-26
Abstract: A method and apparatus for granulating previously molded solid thermoplastic material for recycling by introducing the previously molded thermoplastic material into a cylindrical granulating zone in a direction parallel with the axis of the cylinder, providing a stationary knife at a cylindrical boundary of the granulating zone, moving a second knife along the cylindrical boundary of the granulating zone to pass in proximity to the stationary knife and thereby trap portions of the previously molded thermoplastic material therebetween to cut the previously molded thermoplastic material into granules, providing an apertured surface as a portion of the cylindrical boundary and sweeping portions of the previously molded thermoplastic material along the apertured surface with the moving knife to cause cut portions of the previously molded thermoplastic material having granule size less than that of the apertures to pass therethrough for recycling by subsequent molding or other processing.
Patent AU-3005799-A (AU)
Title: Purification of carboxaldehyde
Inventor: BERGLUND RICHARD ALAN
IPC: C07C47/55
Filed: 1999-03-15
Abstract: The invention is directed to the process of purifying 4'-chloro-4-biphenylcarboxaldehyde.
Patent AU-3197201-A (AU)
Title: Piezoelectric lighter with improved safety
Inventor: CHUNG AMAN KAI MAN
IPC: F23Q2/16
Filed: 2001-02-02
Abstract: A piezoelectric lighter includes a flame-generating device (30) including a gas jet releasing mechanism (36) and spark-generating mechanism piezoelectric mechanism (50). The lighter includes two actuating elements (32, 34; 140, 150, 170, 180; 210, 220; 240, 250) capable of moving along a longitudinal axis (XX') under the action of a force exerted by the user, at least one (32; 140; 170; 210; 240) of the actuating elements, called first actuating element, being capable of moving independently of the second actuating element (34; 150; 180; 220; 250) and to act on at least on one (50) of the mechanisms, called first mechanism, the second actuating element being adapted to act on the second mechanism (36).
Patent AU-3537099-A (AU)
Title: Novel immortalized hepatic cell line originating in humans
Inventor: NANBA MASAYOSHI
IPC: C12Q1/48
Filed: 1999-04-27
Abstract: The present invention relates to a new immortalized hepatocyte culture of human (preferably human fetal) normal cell origin, a method of producing said culture, a screening method for a compound or a salt thereof which inhibits or promotes an enzyme activity involved in the metabolism of xenobiotics in the liver, or which inhibits or promotes the expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, or which inhibits or promotes the induction of expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, characterized by the use of said culture, a compound which inhibits or promotes an enzyme activity involved in the metabolism of xenobiotics in the liver, a compound which inhibits or promotes the expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, or a compound which inhibits or promotes the induction of expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, obtained using said screening method, or salts thereof.  The immortalized hepatocyte culture of human normal cell origin of the present invention is useful in, for example, screening for compounds or salts thereof having therapeutic/preventive effects on hepatic insufficiency .
Patent AU-3661300-A (AU)
Title: Novel method for the production of etoposide
Inventor: GUMINSKI YVES
IPC: C07H17/04
Filed: 2000-03-29
Abstract: The invention relates to a method for the production of etoposide wherein 2,3 - diphenoxyacetyl -1-O-triethylsilyl - beta -D- glucopyranoside is condensed with 4'-phenoxyacetyl-4'-demethylepipodophyllotoxine.
Patent AU-3740699-A (AU)
Title: Viral chimeras comprised of caev and hiv-1 genetic elements
Inventor: DOUVAS ANGELINE
IPC: C07K14/15
Filed: 1999-04-30
Abstract: The present invention provides a polynucleotide comprising portions of the genomes of caprine arthritis-encephalitis virus and HIV-1, resulting in a chimeric retrovirus referred to as a "CHIV." The invention also provides a vaccine comprising a CHIV immunogen and a pharmaceutically acceptable carrier. A method of stimulating an immune response in an individual against human immunodeficiency virus-1 infection by administering a therapeutically effective amount of a CHIV immunogen is also provided. The invention further provides a method of stimulating an immune response in vitro by contacting a lymphocyte with a therapeutically effective amount of a CHIV immunogen.
Patent AU-3811395-A (AU)
Title: Identification of the p21waf1-pcna interaction site and therapeutic applications thereof
Inventor: LANE DAVID PHILIP
IPC: C12Q1/68
Filed: 1995-11-03
Abstract: Substances are disclosed which have the property of binding to PCNA, the substances comprising (i) a fragment of the p21WAF1 protein including residues 141 to 160 of the p21WAF1 amino acid sequence, or an active portion or derivative thereof; or (ii) functional mimetics of these protein fragments. In particular, the PCNA binding activity is shown to lie within the sequence motif OTSMTDFY, with the residues shown in bold being critical for PCNA binding, with those underlined being important. These substances are useful in the treatments of disorders in which PCNA is implicated, e.g. hyperproliferative disorders such as cancer and psoriasis, the substances binding to PCNA to inactivate it or functionally deplete its level. Also disclosed is the use of a yeast two hybrid screening technique for screening candidate peptides for binding to PCNA.
Patent AU-4113093-A (AU)
Title: Bioadhesive microspheres and their use as drug delivery and imaging systems
Inventor: MATHIOWITZ EDITH
IPC: A61K47/26
Filed: 1993-04-23
Abstract: Bioadhesive polymers in the form of, or as a coating on, microcapsules containing drugs or bioactive substances which may serve for therapeutic, or diagnostic purposes in diseases of the gastrointestinal tract, are described. The polymeric microspheres all have a bioadhesive force of at least 11 mN/cm 2  (110 N/m 2 ). Techniques for the fabrication of bioadhesive microspheres, as well as a method for measuring bioadhesive forces between microspheres and selected segments of the gastrointestinal tract in vitro are also described. The quantitative method provides a means to establish a correlation between the chemical nature, the surface morphology and the dimensions of drug-loaded microspheres on one hand and bioadhesive forces on the other, allowing the screening of the most promising materials from a relatively large group of natural and synthetic polymers which, from theoretical consideration, should be used for making bioadhesive microspheres.
Patent AU-4156493-A (AU)
Title: Compositions containing retinoic acids and tocopherol
Inventor: FIEDLER NAGY CHRISTA
IPC: A61K8/00
Filed: 1993-06-28
Abstract: Compositions of retinoic acids and tocopherols may be applied topically without producing retinoic acid-induced skin irritation.
Patent AU-4164400-A (AU)
Title: Tube-encased fiber grating
Inventor: FERNALD MARK R
IPC: G02B5/18
Filed: 1999-12-06
Abstract: A tube-encased fiber grating includes an optical fiber 10 having at least one Bragg grating 12 impressed therein which is embedded within a glass capillary tube 20. Light 14 is incident on the grating 12 and light 16 is reflected at a reflection wavelength lambd1. The shape of the tube 20 may be other geometries (e.g., a "dogbone" shape) and/or more than one concentric tube may be used or more than one grating or pair of gratings may be used. The fiber 10 may be doped at least between a pair of gratings 150,152, encased in the tube 20 to form a tube-encased compression-tuned fiber laser or the grating 12 or gratings 150,152 may be constructed as a tunable DFB fiber laser encased in the tube 20. Also, the tube 20 may have an inner region 22 which is tapered away from the fiber 10 to provide strain relief for the fiber 10, or the tube 20 may have tapered (or fluted) sections 27 which have an outer geometry that decreases down to the fiber 10 and provides added fiber pull strength. Also, the tube-encased grating 12 exhibits lower mode coupling from the fiber core to the cladding modes due to the increased diameter of the cladding where the tube 20 is fused to the fiber 10 where the grating is located 12.
Patent AU-4228999-A (AU)
Title: Parallel fixed bed reactor and fluid contacting apparatus and method
IPC: G01N30/24
Filed: 1999-06-02
Abstract: The present invention relates to an apparatus for evaluating catalytic performance of members of a catalytic library, the apparatus comprising a reaction vessel assembly comprising a plurality of reaction vessels adapted for receiving catalyst library members, each of the plurality of vessels having an inlet and an outlet; a fluid handling system for providing fluid flow simultaneously through the plurality of vessels; and a detector for simultaneously analyzing vessel effluents of at least two of the plurality of vessels, the fluid handling system comprising an entrance control volume in fluid communication with the inlet of each of the plurality of vessels, a plurality of flow restrictors, and an exit control volume in fluid communication with the outlet of each of the plurality of vessels, each of the plurality of flow restrictors being other than a flow controller and being arranged upstream or downstream of one of the plurality of vessels, and wherein each of the plurality of flow restrictors provides fluid communication between one of the plurality of vessels and the entrance control volume or the exit control volume, and wherein maintaining a pressure in the entrance control volume higher than in the exit control volume results in fluid flow through the vessels, the flow restrictors being adapted such that the resistance to fluid flow is greatest in the flow restrictors and the resistance to fluid flow in each of the flow restrictors is approximately the same so that fluid flow through the vessels is apportioned approximately equally between each of the plurality of vessels.