Patent SG-11201810629Q-A (SG)
Title: New piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them
Inventor: Kotschy András 
IPC: C07D495/04
Filed: 2017-06-09
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 14 December 2017 (14.12.2017) WIP0 I PCT ill~~~~~~~~ 011101tIIl two Hol omoiollm mina mil (10) International Publication Number WO 2017/212012 Al (51) International Patent Classification: CO7D 487/04 (2006.01) A61K 31/519 (2006.01) CO7D 495/04 (2006.01) A61P 35/00 (2006.01) (21) International Application Number: PCT/EP2017/064067 (22) International Filing Date: 09 June 2017 (09.06.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1655392 10 June 2016 (10.06.2016) FR (71) Applicants: LES LABORATOIRES SERVIER [FR/FR]; 35 me de Verdun, 92284 SURESNES (FR). VER- NALIS (R&D) LIMITED [GB/GB]; 100 Berkshire Place, Wharfedale Road, Berkshire, WINNERSH Berkshire RG41 5RD (GB). (72) Inventors: KOTSCHY, Andras; Almos Vezer utca 4, 2045 Torokbalint (HU). WEBER, Csaba; Szentendrei ut- ca 9, 2009 Pilisszentlaszlo (HU). VASAS, Attila; Eori Bar- na u. 65, 2151 Foi (HU). MOLNAR, Balizs; Fenyves ut- ca 3, 2117 Isaszeg (HU). KISS, Arpad; Filst Milan utca 6, 3/10, 1039 Budapest (HU). MACIAS, Alba; 12 Beaulands Close, Cambridge Cambridgeshire CB4 1JA (GB). MUR- RAY, James Brooke; 21 Parsonage Way, LINTON Cam- bridgeshire CB21 4YL (GB). LEWKOWICZ, Elodie; 93 avenue Denfert Rochereau, 75014 Paris (FR). GENESTE, Olivier; Batiment A, 17, me Crevel Duval, 92500 RUEIL MALMAISON (FR). CHANRION, Maya; 14 rue de la Galiote, Apt D441, 92130 ISSY LES MOULINEAUX (FR). DEMARLES, Didier; 21 me du Lievre, 45430 CHECY (FR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: NEW PIPERIDINYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COM- POSITIONS CONTAINING THEM (57) : Compounds of formula (I) wherein R1, R2, R3, n and W 1-1 OH are as defined in the description. Medicaments. 1-1 W (RA R , ( 1 ) 1-1 O O 0