baber/WOPTO huggingface dataset:
Patent PT-99562-A (PT)
Inventor: BELLOCQ JEAN-PIERRE
IPC: C12R1/91
Filed: 1991-11-20
Abstract: The present invention relates to a gene encoding a new member of the metalloproteinase family which has been found to be specifically associated with invasive breast cancer, and to methods of diagnosis for such cancer comprising detection of the marker or its nucleotide sequence, and to treatment or prophylaxis by inhibiting, altering the activity of or binding the marker, or by interfering with its synthesis.
Patent UA-9774-A (UA)
Title: Method for measurement of temperature
Inventor: BARDYLO PETRO ILLICH
Filed: 1987-12-02
Abstract: The invention relates to thermometry and can be used for measurement of temperature of especially important objects operated without termination during long time period (more than one thousand hours) by means of thermocouples. Method for temperature determination is in measurement of thermo-electromotive force of first thermocouple installed on object, with additional electrode identical by material to one of main thermo-electrodes. One measures thermo-electromotive force of second thermo-couple formed by second main thermo-electrode of first thermo-couple and additional thermo-electrode. By thermo-electromotive forces measured one determines value of coefficient of thermo-electromotive force of first thermo-couple by which temperature looked for is determined.
Patent UA-13761-A (UA)
Title: Analyzer of envelope of signal of three-phase network
Filed: 1989-11-09
Abstract: The invention relates to electric measuring engineering, devices used for control and analysis of quality of electric energy by oscillation of voltage in three-phase networks with suddenly varying loads. Analyzer of envelope of signal of three-phase network includes three-phase measuring transformer, filter of symmetrical component of direct sequence, controlled key, three blocks of selection-storage, rectifier, register, block for separation of effective values, control block and amplifier. There are included voltage divider, source of compensation voltage, low frequency filter, weighting filter, delay element, quadrator, collecting adder, scaling block and block for extraction of square root.
Patent UA-13143-A (UA)
Title: Method of restoration of worn cylindrical parts
Filed: 1991-02-11
Abstract: Around the component is winded a metallic tape, whose length corresponds to the length of the circle of component, and is accomplished the contact welding of tape to the component along the helix. By welding the tape its edges and joint are connected with the component by continuous seam welding.
Patent UA-15863-A (UA)
Title: Channel-channel adapter
Filed: 1991-04-16
Abstract: The aim of the invention is enhancement by means of providing for information transfer by several addresses.
Patent BG-102436-A (BG)
Title: Portable fertility tester
Inventor: RAUSNITZ GERALD J
IPC: A61B10/00
Filed: 1998-05-08
Abstract: The tester is used in human medicine. By it the samples canbe stored for comparative analysis. The tester contains a case (3)with a light source on which a revolving disc (21) is fittedhaving object glasses (23) positioned along its periphery. A cover(1) with an optical system (51) and a window (53) is fitted on thedisc (21). The tester is used for testing the microscopic patternof the structure of the saliva which can be ferny-type orpoint-type and is a sufficiently reliable indicator for theovulation or the nonovulation period of the woman.8 claims, 5 figures
Patent BG-104510-A (BG)
Title: Prophylactic means for stimulating metabolic processes in cells
Inventor: LAZAROVA KARMEN G
IPC: A61K31/25
Filed: 2000-06-05
Abstract: The means shall find application as an ecologically pure product with prophylactic effect for maintaining the tonus and the elasticity of the cells, for removing cellulitis and/or as means for losing weight by causing a cooling effect. It consists of an activating concentration of camphor  48-49.99 %, methanol 48-49.99 %, vitamin A concentrate 2-0,01 % and vitamin E 2-0.01 %. 3 claims
Patent BG-105381-A (BG)
Title: Method for overlaying inscriptions over background cinema image shot in advance
Inventor: LAZAROV NIKOLAJ S
IPC: G03F3/00
Filed: 2001-03-26
Abstract: According to the method the masking of the background cinema image is made by a second exposition on optical copying machine from one film square shot in advance with transparent letters on a black background. After copying the background image from the original negative on the dubpositive of the latent background image, by a second exposition the mask of the inscription made in advance is copied in, which after standard chemical treatment of the dubpositive acquires the required black colour. From the thus produced dubpositive, a dubnegative is copied, wherein, on the latent background image in the zone of the mask, a colour or white exposition of the same inscription is added. Due to the large size of the black mask in comparison with the mask of the coloured letters, white background is formed around the coloured letters. After the copying of the dubnegative on a standard positive and screen projection, around the coloured letters black background is observed, which ensures good readability of the inscriptions. 1 claim, 2 figures
Patent BG-106035-A (BG)
Title: Heterocyclically substituted benzimidazoles, the production and utilization thereof
Inventor: LUBISCH WILFRIED
IPC: C07D235/18
Filed: 2001-10-22
Abstract: The present invention relates to novel benzimiazoles, the production thereof and the utilization as inhibitors of the enzyme poly(ADP-ribose)polymerase of PARP (EC 2.4.2.30) for producing medicaments. 22 claims
Patent BG-109687-A (BG)
Title: Antiasthmatic drug
Inventor: HRISTOV IVAN
IPC: A61K31/52
Filed: 2006-09-26
Abstract: The antiasthmatic drug finds application in human medicine for the treatment of bronchial asthma and asthmatic bronchitis. It helps to overcome even the most serious asthma attacks within 30 or 40 minutes, as well as to avoid any further cases of hard asthmatic breathing and asthma attacks for a period of 10 - 20 years or even longer, i.e. in actual fact asthma gets fully cured. Besides, the side effects and complications of corticosteroids are avoided. The drug is characterized by good tolerability and does not cause any complications. Its ingredients in mg are: pure caffeine 30,00 to 250,00; ergotamintartarat 0,25 to 2,00; zinc sulphate 10,00 to 400,00; papaverine hydrochloride 30,00 to 200,00; atropine sulphate 0,25 to 1,00; aminophylline 40,00 to 250,00; glaucine hydrochloride 30,00 to 200,00; calcium sulphaguaiacolas 100,00 to 600,00; and chloropyramine 30,00 to 200,00.
Patent BG-110280-A (BG)
Title: Resistors for oltc
Inventor: GROZDANOV TONI
IPC: H01C3/00
Filed: 2008-12-17
Abstract: The resistors are used in the OLTCs for limitation of the circulation current arising during the short term connection of two adjacent taps of the controlled winding of the transformer during the tapchanging. The bearing structure and the appearance of each resistor are unified for the different types of OLTC. The uniform design of the resistor consists of an isolation cylinder (7) fixed tightlybetween the lower isolation cap (8) and the isolation cap (9). The resistor package (1) is situated inside the isolation cylinder (7). It consists of zigzag cut metal strip (3) and thin isolation tape (4) rolled on a circular arbour (2) and fixed externally at several places with string (6). The bearing structure is fixed to an isolation plate (10) by means isolating pin (11) and isolation nuts (12).
Patent BG-111157-A (BG)
Title: Cooling bag
Inventor: TANEV DEYAN
IPC: A45C15/00
Filed: 2012-03-05
Abstract: Cooling bag is used for cooling the body. This is achieved by a fan hanging on strap provided with a pocket for the diversion of the air flow at right angles to the body and the head of the person. The power supply of the cooling bag is provided by a rechargeable battery.
Patent CN-1285710-A (CN)
Title: 表面安装机上的印刷电路板的输送装置
Inventor: CHI-HYON HWANG
IPC: H05K13/04
Filed: 2000-02-01
Abstract: 一种表面安装机上的印刷电路板输送装置,包括:一个机架;一个能在X、Y轴线上移动的XY台架;一个位于XY台架内侧的底座;一个设置在上述底座上部、能检测到从投入口供入的印刷电路板并决定其位置的传感器;一个印刷电路板的输送装置;以及至少一个在借助于上述印刷电路板的输送装置输送过来的印刷电路板上安装电子零件用的、设置在上述XY台架上的捡抬头组件。
Patent CN-1353549-A (CN)
Title: 带有分时立体图像功能的电视机
Inventor: WU XIAOPING
IPC: H04N13/04
Filed: 2000-11-08
Abstract: 一种带有分时立体图像功能的电视机,是利用场识别信号使相临两场或两帧的图像扫描脉冲相位产生少许偏差(即:延时),或者采用数字化的视频信号的逐帧(或逐场)的群位移方式来实现光栅的水平方向的一定位移,使两帧图像产生水平方向的一定位置偏差,从而获得分时的立体图像效果。这种带有分时立体图像功能的电视机,具有较低的成本及较简易的电路结构,可以利用普通电视节目产生立体图像效果,能够更容易地在民品电视机中实施推广。
Patent CN-1408049-A (CN)
Title: 涡轮机
Inventor: TIEMANN P
IPC: F01D25/24
Filed: 2001-02-23
Abstract: 本发明公开了一种涡轮机(6)，特别是燃气轮机。根据本发明，设置了带有接收区(50)的密封元件(44)，用于密封在涡轮机(6)圆周方向(36)上彼此相邻的导向叶片(18)。导向叶片(18)的垫块(21)延伸进所述接收区中。垫块(21)的边缘区域与传统密封相比不需加固，其能使整个垫块均匀冷却。因此，可采用封闭的冷却系统(62)，特别是以蒸汽冷却。
Patent CN-1389893-A (CN)
Title: 具有改进的白色点的等离子体图像屏幕
Inventor: BEHETR H H
IPC: H01J11/40
Filed: 2002-05-04
Abstract: 本发明涉及具有改进的白色点的等离子体图像屏幕。等离子体图像屏幕的前板(1)在面对等离子体放电的一侧的具有蓝色层。这可以是电介质层(4)、保护层(5)或另外的层。
Patent CN-1423035-A (CN)
Title: 排气净化系统及其再生控制方法
Inventor: MASASHI KABU
IPC: B01D46/42
Filed: 2002-11-28
Abstract: 一种排气净化系统,在包括对柴油发动机的排气中的颗粒状物质进行净化处理的DPF的该排气净化系统中,备有再生控制装置,该再生控制装置在对上述DPF进行再生的再生控制运转的开始时与再生控制运转中,判断发动机的运转状态是否为怠速运转,在判定处于怠速运转中时,进行使怠速转数上升到规定的旋转次数的控制通过上述方案,在DPF再生控制运转中,即使在怠速运转时,仍可确保合适的排气流量,避免由于排气流量的减少造成的DPF的升温,防止DPF的熔损,催化剂的性能变差。
Patent CN-1526004-A (CN)
Inventor: MATTURRO MICHAEL G
IPC: C10C3/06
Filed: 2002-03-05
Abstract: 从沥青生产柴油燃料原料的方法使用由气体转化工艺生产的蒸汽，石脑油和加氢异构化的柴油馏分，以分别(i)促进沥青的生产，(ii)稀释它用于管线输送到改质设备，和(iii)通过将它与加氢异构化的气体转化柴油馏分共混，而增加通过改质沥青生产的加氢处理的柴油燃料馏分的十六烷值，以形成柴油原料。此柴油原料的十六烷值高于仅从沥青生产的十六烷值，且可用于共混和形成柴油燃料。
Patent CN-1535380-A (CN)
Inventor: TITBALL R W
IPC: G01N27/62
Filed: 2002-05-22
Abstract: 一种通过生物标记的质谱快速鉴定未知微生物的方法，所述生物标记分离自微生物的裂解物，所述方法基于生物标记在物种之间的结构上的相似性。本发明也公开了所述生物标记，特别是Hsp60。
Patent CN-1605229-A (CN)
Inventor: RAIYOMAND ASPANDIAR
IPC: H05K3/34
Filed: 2002-11-26
Abstract: 一种装置与方法，所述装置用于在对后来安放到双面印刷电路板的一个面上的其它元件进行回流期间，保持该双面印刷电路板的反向面上的已装配元件；所述方法用于制造和使用该装置。环氧树脂材料形成的保持器被配置为与随后被安放到印刷电路板上的元件相耦合。在后面的回流焊步骤期间，印刷电路板周围的环境温度升高，并且环氧树脂材料被配置成进入半液态，并且流到印刷电路板上并粘附于印刷电路板。在达到一般回流焊温度之后，液化环氧树脂材料被配置为固化或硬化，并且当印刷电路板随后被倒置、安装元件并回流时，该环氧树脂以粘附的方式将元件耦合到印刷电路板上。
Patent CN-1482013-A (CN)
Inventor: YEAN-KOO LEE
IPC: G06F17/50
Filed: 2003-05-15
Abstract: 本发明提供了一种预测车辆动态行为特征的方法，其包括：开发用于准静态分析的车辆模型；进行车辆在转弯状态下受专门的横向力作用时的准静态分析；通过准静态分析，基于车辆模型关于地面的刚体位移确定有限螺旋轴线；确定由有限螺旋轴线的偏移形成的固定螺旋轴线表面；计算车辆模型在初始转弯状态下的行为中，相应于横向力的螺旋参数的变化率；基于固定螺旋轴线表面和螺旋参数的变化率估计横向摆动行为。
Patent CN-1469031-A (CN)
Inventor: HIROSHI TAKANO
IPC: B21D39/06
Filed: 2003-06-13
Abstract: 一种发动机的组合式凸轮轴(10)包括：凸轮凸部件(12)；和中空轴件(11)，该中空轴件具有至少两个轴固定表面(11A)，这些表面通过塑性过程形成在与发动机的汽缸之间的位置相对应的一部分中空轴件(11)上。
Patent CN-1620267-A (CN)
Inventor: HEINRICH SCHUBERT
IPC: A61B17/11
Filed: 2003-01-24
Abstract: 本发明涉及一种用于在空心器官1、2之间产生吻合的装置，包括一个绕第一空心器官1的末端安装的内套3和一个绕第二空心器官2的末端安装的外套4，第二空心器官的末端设置在外翻到内套3外面的第一空心器官1的末端之上，其中，内套和外套3、4构成为可拆除的。为了达到可靠的、持久的和可简单实施的吻合，按照本发明设定，内套3和外套4具有导电的材料，例如以接触表面5、6的形式，它们可与一个外部的电流或电压源9相连接以便施加一个电流或电压，用以电凝固待连接的空心器官1、2。
Patent CN-1633796-A (CN)
Inventor: MILLER-SMITH RICHARD M
IPC: H04L12/801
Filed: 2003-01-29
Abstract: 一个在广播系统或移动网络的前端处的路由器缓存所有经过的TCP/IP分组。该路由器周期性地从其缓存器重新发送在客户端没收到的任何数据分组。该系统使得TCP/IP能够被很容易地实现，而不会导致生成大量返回通信量，同时保持着相同接口。
Patent CN-86104989-A (CN)
IPC: C08K5/12
Filed: 1986-08-13
Abstract: 本发明涉及一种无毒增塑剂环氧大豆油的生产工艺及配方。本方法在不含任何溶剂或者促进剂条件下，用大豆油、双氧水、浓硫酸、冰醋酸一步合成，消除了可能污染产品的化学因素，产品环氧大豆油的环氧值在6.0～6.4之间。
Patent CN-1088178-A (CN)
Title: 用于输送物品的流体输送系统
Inventor: SKOW LYNN R
IPC: G11B17/00
Filed: 1993-07-14
Abstract: 用于输送物品的输送装置，包括一平板件，有一
工作面，其结构可接收物品，两排孔延伸穿过平板件，
通过孔供给的流体在两横向穿过孔的出口，并提供一
移动力，可输送物品，同时提供支承物品的压差。
Patent CN-1163316-A (CN)
Inventor: ZHOU FEI
IPC: C22C45/08
Filed: 1997-02-25
Abstract: 一种纳米铝-铅复合材料，Pb的含量占2～40wt％，其特征在于：Al和Pb的平均晶粒尺寸均小于100nm，Al和Pb达到十分均匀弥散的复合，其间不互溶，单个Pb颗粒均匀镶嵌在Al基体上，与基体间无严格的晶体学关系。本发明机械性能优异，工艺易于实现。
Patent CN-1235658-A (CN)
Title: 微加工流体装置及制造方法
Inventor: MAILLEFER D
IPC: F15C5/00
Filed: 1997-10-01
Abstract: 本发明涉及一种微加工流体装置(10),包括一个带有流动管(14)的基体(12)和一个可延展薄层(18),如泵送膜或形成止回阀的膜。薄层(18)是一个轧制金属片,最好由钛制成,并在流动管的覆盖区(20)通过阳极焊接与基体(12)连接。本发明用于制造止回阀。
Patent CN-1217256-A (CN)
Title: 圆环活页夹用的装配和拆卸装置
Inventor: ZHENYUAN DU
IPC: B42F13/22
Filed: 1998-07-29
Abstract: 一种紧固件装置,它用于将一个纸张固定装置松脱式紧固到一个盖件上,该紧固件装置包括一个板件,此板件紧固到盖件上并且其中具有一个孔。一个销钉件被往复式安装到纸张固定装置上,同时销钉件的一部分可选择性地定位在孔中,以将纸张固定装置紧固到盖件上。因此,纸张固定装置可由一位使用者很容易重复地组装到盖件上或从盖件上拆卸下来。因此,纸张固定装置和盖件可以在一种未组装的状态下以一种很紧凑的包装发运,用于以后由客户装配。
Patent CN-1218330-A (CN)
Title: 增益控制方法和电路
Inventor: GOTOU KAZUHUMI
IPC: H04B1/16
Filed: 1998-11-03
Abstract: 增益控制电路控制一个可变增益放大器的增益,用于放大多个预定发送速率的至少之一的射频信号。从该可变增益放大器所放大的接收信号检测该接收信号的电平并且确定接收信号的发送速率。随后,根据以接收信号的电平和接收信号的发送速率为基础产生的增益控制信号控制调节该可变增益放大器的增益。
Patent CN-1252855-A (CN)
Title: 流体机械
Inventor: MAKOTO KOBAYASHI
IPC: F04D15/00
Filed: 1998-04-22
Abstract: 本发明公开一种流体机械,其利用电动机进行驱动,通过叶轮旋转从而产生压力,其具有向电动机供应电力的变频器F、频率和电流值的检测装置,以及预先对频率和电流值的关系进行规定的程序,将实际运转时的频率和电流值与上述规定程序进行比较,对变频器F的发生频率进行调整,使流体机械的运转点靠近上述规定程序。
Patent CN-1235109-A (CN)
Inventor: KUROMOTO TOSHINORI
IPC: B62K11/04
Filed: 1999-04-23
Abstract: 本发明提供一种能降低重心及车座高度的小型摩托车的储藏箱,该小型摩托车在把手1与车座2之间设置低台形的搁脚板3,发动机4在该搁脚板3的附近固定配置在车架5上,该发动机4上设有可以前端部的枢轴7为中心上下自由摆动的后臂8,后轮10支承在该后臂8后端部上,储藏箱29配置在上述车座2的下侧,该储藏箱29将头盔储藏部29a配置在上述发动机4与后轮10之间的枢轴7上方的空间内。
Patent CN-1251872-A (CN)
Title: 一种狭窄环境中快速施工地下基坑支护结构的方法
Inventor: CAI HUILIANG
IPC: E02D29/02
Filed: 1999-11-09
Abstract: 本发明公开了一种狭窄环境中快速施工地下基坑支护结构的方法。在所施工对象的周围开挖支护挡墙基槽后,在短时间内即以该基槽的槽壁代替模板并在基槽内浇灌砼;所述支护挡墙的宽度依据挡土墙的受力情况确定,支护挡墙的深度应大于地下建、构筑物的埋深。
Patent CR-20120044-A (CR)
Title: Preparación de (r) y (s)-n-(3,4-difluoro-2-(2-fluoro-4-yodofe-nilamino)-6-metoxifenil)-1-(2,3-dihidroxipropil)ciclopropan-1-sulfonamida y derivados protegidos de los mismos
Inventor: MADERNA ANDREAS
IPC: C07C303/38
Filed: 2012-01-23
Abstract: La presente invención se relaciona con la preparación de (R)-N-(3,4-difluoro-2-(2-fluoro-4-yodofe-nilamino)-6-metoxifenil)-1-(2,3-dihidroxipropil)ciclopropan-1-sulfonamida y (S)-N-(3,4-difluoro-2-(2-fluoro-4-yodofe-nilamino)-6-metoxifenil)-1-(2,3-dihidroxipropil)ciclopropan-1-sulfonamida.
Patent CR-20190471-A (CR)
Inventor: SWAYZE ERIC E
IPC: C12N15/113
Filed: 2018-03-23
Abstract: Las presentes realizaciones proporcionan métodos, compuestos y composiciones útiles para inhibir la expresión de PCSK9, lo que puede ser útil para tratar, prevenir o mejorar una enfermedad asociada con PCSK9.The present embodiments provide methods, compounds, and compositions useful for inhibiting PCSK9 expression, which may be useful for treating, preventing, or ameliorating a disease associated with PCSK9.
Patent CR-20190545-A (CR)
Title: 5,6-fused-bicyclic compounds and compositions for the treatment of parasitic diseases
Inventor: LERARIO ISABELLE K
IPC: C07D519/00
Filed: 2018-05-29
Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Patent CR-20220177-A (CR)
Title: Aparato y dispositivo de electroestimulación cutánea
Inventor: MADELEIN CENTENO RODRIGUEZ CASADA
Filed: 2022-04-22
Abstract: La presente divulgacion se relaciona con aparatos y dispositivos de electroestimulacion cutanea empleados en procedimientos esteticos y quirurgicos. El dispositivo de electroestimulacion cutanea puede incluir un elemento de acople que tiene un extremo proximal configurado para conectarse a una fuente de potencia y un extremo distal; y un elemento de soporte conectado al extremo distal del elemento de acople. Ademas, el dispositivo puede incluir un cuerpo rotacional conectado al elemento de soporte mediante un eje, donde el cuerpo rotacional tiene una pluralidad de agujas que se extienden radialmente hacia afuera. La fuente de potencia puede estar configurada para obtener corriente electrica con una onda de salida que tiene un voltaje entre 240 V y 4.700 V y una potencia entre 50W y 350W. Ademas, el elemento de acople puede estar configurado para recibir la potencia electrica generada por la fuente de potencia y transmitir la potencia electrica a traves del elemento de soporte y el cuerpo rotacional. Por su parte, el aparato de electroestimulacion cutanea puede incluir una fuente de potencia, y cualquiera de las modalidades del dispositivo de electroestimulacion cutanea descritos en la presente divulgacion. El dispositivo de electroestimulacion cutanea se conecta a la fuente de potencia a traves del extremo proximal del elemento de acople. Ademas, la fuente de potencia se selecciona entre un cauterio electrico, un bisturi electrico, una unidad de electrocirugia, una unidad de generacion de corriente electrica con una onda de salida predeterminada, y combinaciones de las mismas.
Patent CR-20220611-A (CR)
Title: Antibodies to tigit
Inventor: WALKER NIGEL PELHAM CLINTON
IPC: A61P35/00
Filed: 2021-06-01
Abstract: The present disclosure provides antibodies that specifically bind to TIGIT. The antibodies have the capacity for substantial activation of T cells and natural killer cells by inhibiting binding of TIGIT to CD155. The antibodies can be used for treatment of cancer and infectious disease, among other applications.
Patent CR-20230027-A (CR)
Title: Non-refillable dosing capillary insert
Inventor: WHITFIELD ADRIAN MICHAEL
IPC: B65D47/18
Filed: 2020-08-14
Abstract: The invention refers to a capillary insert (100) or cap that comprises a cone (110) in its upper part that ends in a skirt (120) forming a single piece, which leaves evidence if something in the insert (100) has changed or has been altered improperly. The capillary insert or cap of the present invention prevents its reuse and tampering through one or more breaking zones (130) located along the insert.
Patent EC-SP034853-A (EC)
Title: Composición farmacéutica líquida
Inventor: KULKARNI NEEMA
IPC: A61K/
Filed: 2003-11-17
Abstract: Se describe una composición farmacéutica líquida de un análogo de GABA que comprende al menos un alcohol polihidroxílico que contiene de 2 a 6 átomos de carbono, que tiene un pH desde aproximadamente 5,5 a aproximadamente 7, 0, y además una composición farmacéutica líquida en dos componentes que comprende un primer componente que comprende una mezcla de polvo que comprende un análogo de GABA y un alcohol polihidroxílico sólido, y un segundo componente que comprende una base líquida, así como métodos para preparar las composiciones y un método para tratar enfermedades cerebrales, incluyendo epilepsia, ataques de desfallecimiento, hipoquinesia y traumatismos craneales, trastornos neurodegenerativos, depresión, manía y trastornos bipolares, ansiedad, pánico, inflamación, cólico renal, insomnio, trastornos gastrointestinales, incontinencia, dolor, incluyendo dolor neuropático, dolor muscular, dolor esquelético y migraña, utilizando una cantidad terapéuticamente eficaz de las composiciones farmacéuticas
Patent EC-SP077183-A (EC)
Title: Derivados de la n-(1-bencil-4-fenil-1h-imidazol-2-il)-2,2-dimetilpropil)benzamida y los compuestos relacionados como inhibidores de la proteína de quiinesina del huso (ksp) para el tratamiento del cáncer
Inventor: WANG WELBO
IPC: C07D405/12
Filed: 2007-01-18
Abstract: Esta invención se dirige a los compuestos substituidos del imidazol, los cuales, modulan la actividad de la KSP representado por la fórmula I: en donde: R1 se selecciona del grupo que consiste de acilamino, carboxilo, éster de carboxilo, arilo, y alquilo opcionalmente sustituido con hidroxi o halo; R2 se seleccionan del grupo que consiste de hidrógeno, alquilo, y arilo; R3 se seleccionan del grupo que consiste del hidrógeno y - X-A, en donde X se selecciona del grupo que consiste de -C(O) -, - C(S) -, - S(O) -, - S(O)2, y - S(O)2-N(R)-, donde R es hidrógeno o alquilo y A se selecciona del grupo que consiste de hidrógeno, alquilo opcionalmente substituido, del arilo alkoxy, opcionalmente substituido opcionalmente substituido, del éster carboxilo, carboxilo, del aminoacilo, del heteroarilo opcionalmente substituido, del cycloalquilo heterocíclico, y opcionalmente substituido opcionalmente substituido, en donde substituyen a los grupos opcionalmente substituidos con 1 a 4 sustitutos; R5 es seleccionado del grupo que consiste de L-A1, en donde L es seleccionado del grupo que consiste de -S(O)q- donde q es uno ó dos, y el alquenilo de C1 a C5 opcionalmente sustituido con hidroxi, halo, o acilamino; y A1 es seleccionado del grupo que consiste de arilo, arilo sustituido, heteroarilo, heteroarilo sustituido, heterocíclico, heterocíclico sustituido, cicloalquilo, y cicloalquilo sustituido; y uno de tanto R6 ó R7 es seleccionado del grupo que consiste de heterocíclico, arilo y heteroarilo, todos de los cuales pueden estar opcionalmente sustituidos con-(R8)m donde R8 es como se define aquí y m es un número entero de 1 a 3, y los otros de R6 ó R7 es seleccionado del grupo que consiste de hidrógeno, halo, y alquilo; ó R6 y R7 son ambos hidrógeno;
Patent EC-SP920828-A (EC)
Title: Tubo surtidor
Inventor: SUN KAI
IPC: B65D/
Filed: 1992-04-07
Abstract: Un surtidor de tubo que comprende una parte de tubo contínua y tiene una ventana para vista atravezando longitudinalmente dicha parte de tubo contínua, un hombro sobre el extremo superior de la parte de tubo, dicho hombro siendo una boquilla que se extiende hacia afuera desde dicha parte de tubo y teniendo una abertura para entregar substancias que están siendo dispensables desde el tubo, el fondo de dicho tubo estando cerrado.
Patent EC-SP930973-A (EC)
Inventor: DAUPHIN FRIEDRICH WILHELM
IPC: A47C1/032
Filed: 1993-08-19
Abstract: A chair, in particular office chair, is provided with a foot stand (1), with a seat support (4) which is supported thereon by means of a chair column (3) and has a front and a rear seat-support part (12, 13) connected to one another via a pivot pin (20), with a seat (5) supported on the seat-support parts (12, 13), with a back (7) fixed to the rear seat-support part (13) and with an energy storing device (gas spring 27) which is articulated on the seat-support parts (12, 13) at a distance from their pivot pin (20), is adjustable in length and is intended for mutual adjustment of back (7) and seat (5), one seat-support part (12) being equipped with a receptacle (bearing block 47) for the upper end of the chair column (3). The receptacle (bearing block 47) on the seat-support part (12) is articulated via an articulation pin (49) arranged parallel to the pivot pin (20) of front and rear seat-support parts (12, 13). In order to lock and release various inclinations of the seat support (4) with respect to the chair column (3), the seat-support part (12) is provided with a locking device which is operative between the seat-support part (12) and the receptacle (bearing block 47). <IMAGE>
Patent EC-SP941098-A (EC)
Title: Un procedimiento para preparar el ester 1-acetoxietilico de cefuroxima, altamente puro, en forma sustancialmente amorfa
Inventor: CRISP HARLOD ALFRED
IPC: A61P31/04
Filed: 1994-05-26
Abstract: Un procedimiento para preparar el éster 1-acetoxietilico de cefuroxima, altamente puro, en forma sustancialmente amorfa, caracterizado porque; a) se prepara una disolución que contiene de 1 a 30% en masa/masa (m/m) del éster 1-acetoxietílico de cefuroxima en un disolvente orgánico e en una mezcla homogénea de disolventes orgánicos y agua, y b) se somete la disolución a un secado por atomización empleando aire o un gas de secado inerte, a una temperatura de entrada del gas de 50 a 140oC y a una temperatura de salida del gas de 45 a 100oC con lo cual se logra recuperar de dicha disolución de éster 1-acetoxietílico de cefuroxima en una forma altamente pura y sustancialmente amorfa.