baber/WOPTO huggingface dataset:
Patent CA-2286607-A1 (CA)
Inventor: KLUNK WILLIAM E
IPC: C07C65/03
Filed: 1998-04-20
Abstract: L'invention concerne des composés se fixant à la substance amyloïde et qui sont des dérivés non azo de la chrysamine G, des compositions pharmaceutiques comprenant ces composés et des procédés les utilisant dans le but d'identifier in vivo, dans un cerveau, la maladie d'Alzheimer et de diagnostiquer d'autres états pathologiques caractérisés par l'amylose tels que le syndrome de Down. Elle concerne également des compositions pharmaceutiques contenant des dérivés non azo de la chrysamine G ainsi que des procédés d'utilisation de ces compositions visant à empêcher la dégénérescence cellulaire et la toxicité induite par la substance amyloïde dans des états associés à l'amylose. Elle concerne en outre des procédés dans lesquels on utilise des dérivés non azo de la chrysamine G afin de marquer ou de détecter des dépôts de substance amyloïde dans un tissu biopsique ou prélevé post mortem. Elle concerne enfin des procédés d'utilisation de dérivés non azo de la chrysamine G afin de quantifier les dépôts de substance amyloïde dans des homogénats de tissu biopsique ou prélevé post mortem.
Patent CA-2293631-A1 (CA)
Title: Non-competitive threshold ligand-receptor assays
Inventor: ANDERSON RICHARD R
IPC: G01N33/74
Filed: 1998-05-29
Abstract: Assay methods for performing non-competitive ligand-receptor assays, where said assays provide a sensible result when the target ligand identified by the assay is present at a concentration greater than a defined threshold concentration. The threshold concentration can be selected to be the upper limit of a normal range of values for a target ligand in a sample, so that an assay in accordance with the invention provides a sensible result only when the target ligand is present at elevated levels.
Patent CA-2294329-A1 (CA)
Title: Chambre a vide differentielle destinee au transport dirige d'une substance
Inventor: BLOECKER HELMUT
IPC: B01L3/00
Filed: 1998-06-19
Abstract: Dans une chambre à vide comprenant au moins deux zones à vide, on fait passer à volonté des substances, notamment des fluides, d'une zone à l'autre en créant un vide approprié. En utilisant des supports de filtres et d'éléments récepteurs, on peut ainsi faire passer automatiquement un fluide, durant une préparation de plasmides, dans les filtres correspondants. La chambre à vide est alimentée par un robot de préhension automatique et connectée à une commande de ventilation. Du fait que la chambre, avec son robot de préhension et son mécanisme de commande, forme un système de robots de pipetage, il est possible de réaliser automatiquement une préparation de plasmides, par exemple selon le protocole Qiagen.
Patent CA-2300151-A1 (CA)
Inventor: DUPUIS ALAIN
IPC: E06C7/14
Filed: 2000-02-24
Abstract: Un plateau pratique qui s'installe sur une échelle. Un bout du plateau possède un tube qui va se glisser dans un barreau supérieur de l'échelle.  A l'autre bout du plateau sont situées des oreilles entre lesquelles pivo te une tige qui se glisse dans une tige-pipe de façon à pouvoir ajuster l'angle du plateau. Le tige-pipe s'insère dans un barreau inférieur sous celui où passe le tube.
Patent CA-2301640-A1 (CA)
Title: Laminated radio frequency identification device
Inventor: MOSHER WALTER W JR
IPC: G06K19/07
Filed: 1998-09-09
Abstract: An RFID wristband incorporates identification circuitry (50) which may be of a read only, a read/write, a passive, or an active configuration. The wristband consists of a plurality of laminae (30, 32) which bear components of the RFID circuitry (50) and which encapsulate said cirtuitry upon the securement or adherence of said laminae (30, 32) to each or one another. The wristband is incorporated in an identification system particularly adapted for hospital patient identification and is associated with an RFID reader which generates a magnetic signal requesting identification from the wristband. The wristband is automatically assembled by the utilization of at least two laminae (30, 32) of a polymorphic flexible nature to encapsulate the RFID  circuit (50) and includes the utilization of polymeric in conductive components in said circuit. The method of assembling the RFID components (50) with the respective laminae (30, 32) results in the complete isolation of the RFID circuit (50) from contact with deleterious and corrosive substances characteristic of hospital environments.
Patent CA-2305322-A1 (CA)
Title: Method for customizing and managing information in a voice mail system to facilitate call handling
Inventor: CASTAGNA WILLIAM D
IPC: G10L13/04
Filed: 1998-10-01
Abstract: A method and system for organizing and managing information to be used by a voice mail system to facilitate call handling based on information contained in an address book having a database with entries corresponding to information about callers and a user interface. The method comprising the steps of automatically or manually creating an entry in the address book associated with the information about a caller, maintaining the address book based on a set of options provided by the user interface, and managing the voice mail system corresponding to the address book by interacting with the user interface. Calls can be initiated and different calls can be treated differently using the information in the address books.
Patent CA-2306014-A1 (CA)
Title: Shaving implement
Inventor: PENNELLA ANDREW J
IPC: B26B21/40
Filed: 2000-04-18
Abstract: A shaving implement, such as a disposable cartridge or razor, comprises a shaving head which includes a skin-contacting element in the form of a series of cavities and projections. The projections are arranged in the cavities in order to provide a unique sensation to the user during shaving. The cavities are arranged so as to meter the amount of shaving cream which is on the surface being shaved.
Patent CA-2306158-A1 (CA)
Inventor: MERSMANN FRANZ-JOSEF
IPC: C08C4/00
Filed: 1998-09-26
Abstract: In a process for degassing rubber particles from gaseous phase polymerisation, the rubber particles are constantly held in motion in a vibrating fluidised bed and are crossed at the same time by a gas flow.
Patent CA-2307695-A1 (CA)
Inventor: MESHER SHAUN TERRANCE EINAR
IPC: C10G25/00
Filed: 2000-05-05
Abstract: A method for the removal of metals from hydrocarbon stream by passing the oil over a bed of high surface area ceramic material at elevated temperatures. Contact with the ceramic material causes the metals to be absorbed on to the surface of the material and undergo a chemical reaction. The oil after contact with the material contains little or no metals. The metals can be removed from the material by reversing the chemical reaction with the addition of hot steam. The steam has the added benefit of enhancing the material and making it more reactive towards the next metal laden petroleum feedstock. The steam/metal stream can be collected and concentrated to efficiently dispose of the metals taken from the oil.
Patent CA-2308225-A1 (CA)
Title: A coating composition and a method for coating thereof
Inventor: SUGIURA KAZUTOSHI
IPC: C09D163/00
Filed: 1998-10-20
Abstract: An organic-solvent-based thermosetting coating material capable of giving a coating film which has a smooth surface, does not soften even upon exposure to a temperature of 60 ~C or above, and has excellent nonfouling properties and from which adherent fouling substances can be easily removed, and comprising (A) a compound containing two or more alicyclic epoxy groups per molecule and having a number-average molecular weight lower than 2,000, (B) an epoxidized acrylic resin having a number-average molecular weight of 2,000 to 50,000, a hydroxyl value of 10 to 150 mg-KOH/g, and an epoxy equivalent of 220 or lower, (C) a thermally latent and cationically polymerizable catalyst, and (D) either fine polymer gel particles or a combination of colloidal silica with a tetraalkylammonium salt, the molar ratio of the epoxy groups in component (A) to the epoxy groups in component (B) ranging from 1/1 to 1/0.05; and a method for forming a multilayered coating film on an object by successively applying at least one coloring coating material and at least one clear coating material, characterized in that the organic-solvent-based thermosetting coating material is used as a clear coating material for forming the uppermost layer.
Patent CA-2310001-A1 (CA)
Title: Joint
Inventor: DAVIDSON PAUL
IPC: F16L27/12
Filed: 1998-11-18
Abstract: A joint is provided for interconnecting a pipe (11) or other tubular element with a hollow structure (3) having a tubular inlet (7) thereto. The joint includes an annular sealing member (9) which is provided with first and second sealing means (13 and 15). The first sealing means provide sealing engagement between the annular sealing member and the inlet. The second sealing means provide sealing engagement between the annular sealing member and the tubular member. The annular sealing member and inlet are provided with means to secure said sealing member to said inlet to prevent axial movement therebetween, said second sealing means engaging the outer curved surface of the tubular member whereby sealing engagement may be effected between the sealing member and the tubular member over a plurality of relative axial positions therebetween.
Patent CA-2310246-A1 (CA)
Title: Individual packages for absorbent interlabial devices
Inventor: FARRIS DIANE DUNN
IPC: A61F13/472
Filed: 1998-11-12
Abstract: Individual package to assist the hygienic insertion of an absorbent device into the interlabial space of a female user are disclosed. The individual package comprises a wrapper for packaging the absorbent device.  The wrapper comprises a flexible sheet which is wrapped around the absorbent device. The wrapper being at least partially removable from around the absorbent device wherein at least a portion of the wrapper remains between a user's hands and the absorbent device when the absorbent device is inserted into the interlabial space to prevent the user's hands from contacting the absorbent device for hygienic insertion. The wrapper is folded about the absorbent device relative to the longitudinal axis of the lower portion forming a longitudinal fold, an opposing open end, and transverse side edges. The opposing open end and transverse side edges are sealed forming the individual package.
Patent CA-2312613-A1 (CA)
Title: Disposable laminated panel
Inventor: YOSHIOKA TOSHIYASU
IPC: A61F5/44
Filed: 2000-06-28
Abstract: A disposable laminated panel 1 including at least two panel members placed upon and joined to each other by means of adhesive B1, B2 applied on at least one of their surfaces facing each other, wherein the adhesive B1, B2 forms a plurality of independent joining lines undulating in one direction so that these joining lines might neither intersect one another nor intersect themselves.
Patent CA-2312760-A1 (CA)
Inventor: GOULD ELIZABETH
IPC: A61K31/4453
Filed: 1998-12-04
Abstract: A method of preventing and/or treating epileptic seizures in a mammal in need of such treatment, which comprises administration to said mammal of a therapeutic amount of a 5HT1A antagonist.
Patent CA-2315279-A1 (CA)
Title: 14-3-3.sigma. arrests the cell cycle
Inventor: VOGELSTEIN BERT
IPC: C12N15/12
Filed: 1998-12-18
Abstract: Exposure of colorectal cancer (CRC) cells to ionizing radiation results in a growth arrest, with cells blocked in both the G1 and G2 phases of the cell cycle. The G1 block has been shown to be due to the p53-mediated induction of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/SDI1, but the basis for the G2 arrest is unknown. Through a quantitative analysis of gene expression patterns in CRC cell lines, we have discovered that 14-3-3.sigma. is strongly induced by .gamma.-irradiation and other DNA-damaging agents. The induction of 14-3-3.sigma. is mediated by a p53-responsive element located 1.815 kb upstream of its transcription start site. Exogenous introduction of 14-3-3.sigma. into cycling cells results in a G2 block similar to that observed following irradiation. These results document a molecular mechanism for G2/M control that is regulated in human cells by p53.
Patent CA-2315890-A1 (CA)
Title: Rate controlling membranes for controlled drug delivery devices
Inventor: TONG GILBERT T
IPC: A61K9/00
Filed: 1998-12-03
Abstract: This invention provides rate controlling membranes for controlled drug delivery devices that are stable over time and exhibit more predictable and consistent membrane functionality. According to another aspect, the membranes have enhanced permeability. According to the invention, the rate controlling membrane of a controlled drug delivery device is subjected to a pre-treatment annealing process wherein it is subjected to an elevated temperature for a predetermined time period and subsequently cooled to ambient conditions before incorporation into a controlled drug delivery device.
Patent CA-2316076-A1 (CA)
Inventor: HAW DAVID CHARLES
IPC: H04M1/725
Filed: 2000-08-16
Abstract: The present invention features a docking station for connecting a conventional wireline telephone or system of conventional telephones to one or more handheld wireless telephones, enabling a conventional wireline telephone to send calls to and receive calls from a wireless telephone network. This arrangement can eliminate the requirement for a separate wireline telephone service. The wireless telephone may be easily removed from the docking station for independent use as a mobile wireless telephone. The docking station is provided with a specially configured removable connecting sleeve which may be used to connect a particular make and model of handheld wireless telephone to the docking station. The docking station may comprise more than one connecting sleeve so that more than one handheld wireless telephone may be accessed by a wireline telephone connected to the docking station. Docking station circuitry simulates the familiar conventional wireline telephone environment so that a conventional wireline telephone may access the wireless network in the same manner that landline telephone network is accessed.
Patent CA-2320895-A1 (CA)
Title: Systeme d'affichage pour bords de rayons
Inventor: WILKES DEREK ALAN
IPC: G09F3/20
Filed: 1999-02-19
Abstract: L'invention concerne une fixation de raccord destinée à accueillir un rail auxiliaire qui comporte une fente supérieure et une fente inférieure, la fixation de raccord possédant une forme appropriée pour rentrer dans le bord d'un rayon qui comporte des rainures inférieure et supérieure. La fixation de raccord comprend des garnitures supérieure et inférieure dont la forme leur permet de rentrer dans les rainures inférieure et supérieure, respectivement, pour relier la fixation de raccord au bord du rayon. La fixation de raccord comprend en outre une étiquette supérieure et une étiquette inférieure, lesdites étiquettes étant conçues pour rentrer dans les fentes supérieure et inférieure, respectivement, pour relier la fixation de raccord au rail auxiliaire.
Patent CA-2322033-A1 (CA)
Inventor: HILDEBRANDT VOLKER
IPC: C08G69/18
Filed: 1999-02-22
Abstract: The invention relates to a method for producing polyamides by polymerization of lactams in the presence of metal oxides as heterogeneous catalysts.  According to the invention, the metal oxides are placed inside a mold which permits mechanical separation from the reaction mixture and are removed from the reaction mixture during or after completion of the polymerization.
Patent CA-2322328-A1 (CA)
Title: Process for making carboxylic acid esters
Inventor: BLEWETT C WILLIAM
IPC: C07C29/149
Filed: 1999-03-04
Abstract: Sulfur and soap contaminants are removed from carboxylic acid esters by a process comprising the steps of: (1) contacting a carboxylic acid ester with an aqueous base at a temperature of from about 225 ~F to about 280 ~F while removing water to form a dry, crude ester; (2) contacting the dry, crude ester with an absorbent selected from the group consisting of silica gel, hydrosilica gel and mixtures thereof; (3) separating the absorbent from the ester.
Patent CA-2323496-A1 (CA)
Inventor: BATES TIMOTHY
IPC: C07C279/18
Filed: 1999-03-11
Abstract: La présente invention concerne des composés, des compositions, et des procédés utiles pour prévenir et traiter des troubles relatifs à l'état de santé, à la peau, aux cheveux, et à la cavité buccale. Les composés, compositions, et procédés de cette invention peuvent également être appliqués aux domaines de la santé et des soins de la peau, des cheveux, ou de la cavité buccale, ou encore des soins cosmétiques et d'hygiène personnelle. La présente invention concerne en particulier des composés de structure: (1), ainsi que les tautomères, sels acceptables, et amides, esters, et imides biohydrolysables de ceux-ci, A, Q, n, P, L¿1?, L¿2?, L¿3?, L¿4?, Z, X, B¿1?, et B¿2? étant tels que définis dans la description.
Patent CA-2326712-A1 (CA)
Title: Vdt stress mitigating device and method, vdt stress risk quantifying device and method, and recording medium
Inventor: NOMURA MASAHIDE
IPC: G09G5/24
Filed: 2000-11-23
Abstract: The aim of the present invention is to provide a VDT stress mitigating devic e and method capable of mitigating VDT stress caused by a regular spatial pattern and VDT stress caused by flicker generated by an interlaced format, a VDT stress ris k quantifying device and method, and a recording medium. An A/D conversion section 10 imports interlaced format video signals P1 from an external image signal output devi ce and converts them in field units by A/D conversion into image data D1. A filter section 2 0, while not distinguishing between the first field and the second field, and while maintaining the temporal order of these fields, performs a temporal filtering process on the  image data of each field. A D/A conversion section 30 converts the image data D2 that has undergone the temporal filtering process by the filter section 20 into image signals P2 based on an interlaced format by D/A conversion. The image signals P2 are then sequentially outputs according to the temporal order of the fields.
Patent CA-2326846-A1 (CA)
Title: A convergent synthesis of .alpha.-aryl-.beta.-ketonitriles
Inventor: ZHOU JICHENG
IPC: C07C253/00
Filed: 1999-03-29
Abstract: The present invention relates to processes for the production of .alpha.-aryl-.beta.-ketonitriles, which serve as synthetic intermediates in the preparation of a series of biologically important molecules such as corticotropin releasing factor (CRF) receptor antagonists.
Patent CA-2328033-A1 (CA)
Inventor: HUBBARD MARK W
IPC: G06F3/14
Filed: 2000-12-12
Abstract: A system method of interfacing a computer system executing commercial transactions initiated from communication devices, each communication device having a display, with custom display parameters, is provided. For the system and method, at the computer system, for each device, a command is received and translated into a common format command. The common format command is executed and results therefrom are received. A database is accessed having elements identifying sets of display parameters, one set of the sets is for use with the custom display parameters. One set of display parameters is retrieved from the database.
Patent CA-2329640-A1 (CA)
Title: Paper coating lubricant
Inventor: FLOYD WILLIAM
IPC: D21H19/46
Filed: 1999-03-11
Abstract: An aqueous paper and paperboard coating composition is provided containing as a lubricant a vegetable oil triglyceride which is hydrophobic and non-ionic.
Patent CA-2329965-A1 (CA)
Inventor: TRAN HUNG V
IPC: H04Q11/04
Filed: 2000-12-29
Abstract: Techniques which may be used to (1) design and construct a switching device characterized by both reduced buffer space requirements and the ability to handle self-similar traffic and (2) enable a switch to maintain performance standards while experiencing higher levels of self-similar traffic are disclosed herein have been achieved by a discover that below a certain utilization factor threshold value of approximately 38%, the size of the buffer space needed to handle self-similar traffic is less than that commonly believed while, above that utilization factor threshold value, the size of the buffer space needed to handle self-similar traffic is greater than that commonly believed.
Patent CA-2330231-A1 (CA)
Title: Composition et methode permettant de moduler l'interaction entre cellules dendritiques et lymphocytes t
Inventor: FIGDOR CARL GUSTAV
IPC: A61K39/00
Filed: 2000-04-19
Abstract: La présente invention concerne l'utilisation d'un composé se liant à une lectine de type C à la surface d'une cellule dendritique dans la préparation d'une composition destinée à moduler, notamment à réduire, la réponse immunitaire chez un animal, en particulier un humain ou autre mammifère. Cette composition permet notamment de moduler les interactions entre une cellule dendritique et un lymphocyte T, plus précisément entre une lectine de type C à la surface d'une cellule dendritique et un récepteur ICAM à la surface d'un lymphocyte T. Ces compositions peuvent être utilisées pour empêcher/inhiber certaines réponses immunitaires vis-à-vis d'antigènes spécifiques, pour induire une tolérance, pour l'immunothérapie, pour l'immunosuppression, pour le traitement des maladies auto-immunes ou le traitement des allergies, et/ou pour inhiber l'infection au VIH. Le composé se liant à une lectine de type C est choisi, de préférence, parmi le mannose, le fucose, les lectines végétales, les antibiotiques, les sucres, les protéines ou les anticorps dirigés contre les lectines de type C. L'invention concerne également ces anticorps, ainsi qu'une méthode permettant d'isoler des cellules dendritiques à l'aide desdits anticorps.
Patent CA-2331383-A1 (CA)
Title: Multilayered cvd coated article and process for producing same
Inventor: NARASIMHAN KRISHNAN
IPC: C23C16/44
Filed: 1998-11-10
Abstract: The invention relates to a cemented carbide or ceramic article having a multilayered coating of a plurality of ultrathin CVD coating layers, and a process for producing same. Each of the ultrathin CVD coating layers has a thickness of approximately 200 nanometers or less. The multilayered coating ranges from approximately 50-400 layers, has excellent adherence and a smoothness and a hardness of at least approximately 40 GPa. The CVD coated article of the present invention exhibits improved coating properties of excellent smoothness, uniformity, toughness, hardness and abrasive wear resistance.
Patent CA-2331746-A1 (CA)
Title: Method and apparatus for electrically controlling a flow of material
Inventor: HATJASALO LEO
IPC: B24B13/00
Filed: 1999-04-28
Abstract: The invention relates to a method for electrically controlling a flow of material, wherein a single- or multi-component, essentially polymer-based material (1), such as plastics elastomer or the like, is charged electrically (I) and sprayed (II) in an electrical field (E) to a three-dimensional mould (2)/target (3). The method of the invention makes use of the mould (2)/target (3) set at an electric potential and provided with two or more treatment blocks (Li) to be set at voltage levels different from each other, especially for coordinating the courses of sprayed material particles and the electrical field (E) affecting the same, in such a manner that each section/area of the mould/target surface forms a material layer of desirable thickness in the spraying cycle (II). The invention relates also to an apparatus operating in accordance with the method.
Patent CA-2332124-A1 (CA)
Inventor: BALKOS NIKOLAS D
IPC: A23L13/60
Filed: 2001-01-25
Abstract: A press for making a patty includes a substantially flat panel to contact the product to be pressed into a patty. An upstanding member is affixed to the panel. A weight member or "mould" surrounds the upstanding member. The weight member is moveable along the upstanding member between a first position where the weight member overlies the panel to facilitate the application of force to the product and a second position where the weight member is spaced from the panel.