baber/WOPTO huggingface dataset:
Patent DE-10294574-D2 (DE)
Inventor: HECKER MARKUS
IPC: A61P9/00
Filed: 2002-10-02
Granted: 2004-07-22
Abstract: Decoy oligonucleotides (I) having any of the 39 nucleotide sequences defined in the specification. An independent claim is also included for three antisense molecules (II) selected from S1, S2, and S3. TACCACTGAGACATCCTGCCAC (S1); AACATCATTGGCACGCAG (S2); GTGAACCTGCTCCAG (S3). ACTIVITY : Vasotropic; Immunosuppressive; Antidiabetic; Neuroprotective; Antiallergic; Antirheumatic; Antiinflammatory; Dermatological; Antiarthritic; Antiasthmatic; Antipsoriatic; Antibacterial. Guinea pigs were sensitized to dinitrochlorobenzene (DNCB), then treated again with DNCB to induce contact dermatitis. Intradermal injection of the STAT-1 decoy oligonucleotide (TGTGAATTACCGGAAGTG) 1 hour before final exposure to DNCB caused a significant reduction in edema, the number of apoptotic cells and leucocyte infiltration, i.e. significant suppression of the inflammatory response. MECHANISM OF ACTION : Neutralization, or inhibiting expression of, STAT-1, and thus of a range of potentially proinflammatory gene products in leucocytes, endothelial and smooth muscle cells. Genes that have a STAT-1 binding site in their promoters include those for CD40, E-selectin, inducible nitric oxide synthase (NOS), interleukin-12 and interferon-gamma . Also (I) may lift inhibition of gene expression where this is blocked by transcription factors, e.g. the gene for endothelial NOS which is down regulated by interferon-gamma .
Patent DE-19680811-D2 (DE)
Inventor: KALT WOLFRAM
IPC: B29C48/694
Filed: 1996-09-24
Granted: 1997-12-11
Abstract: The invention is concerned with a process for transporting a solution of cellulose in an aqueous tertiary amine-oxide through a component wherein said cellulose solution has different flow rates in said component, characterized in that an outlet wherethrough part of said cellulose solution is discharged from said component is provided at a point within said component whereat said flow rate is relatively low. (FIG. 2)
Patent DE-19781483-D2 (DE)
Inventor: VORBACH MARTIN
IPC: G06F15/78
Filed: 1997-12-21
Granted: 2000-01-05
Abstract: The system has several bundled individual lines or busses or partial busses inside a component with a two- or multi-dimensional programmable cell structure, enabling the component to be combined with others and/or connected to memories and/or peripherals. One or more interfaces are used to combine the lines and set up the bus system. The interfaces are controlled by one or more state machines.
Patent BR-PI1000759-E2 (BR)
Title: preparado à base de óleos vegetais usado como suplemento nutricional
Inventor: VASCONCELOS PAULO ROBERTO LEITÃO DE
IPC: A23D9/013
Filed: 2010-03-18
Abstract: preparado à base de óleos vegetais usado como suplemento nutricional. é descrito um preparado à base de óleos vegetais, com a opção de acréscimo de óleo de peixe e/ou ácidos graxas poliinsaturados, usado como suplemento nutricional sob a forma de um mix lipídico para ser adicionado a todo tipo de alimento, inclusive como alimento funcional, per si, e/ou adicionado à nutrição enteral ou parenteral de pacientes graves internados em uti, e/ou na fabricação de laticínios.
Patent MD-1471-F1 (MD)
Title: Antibacterial and antifungal medicinal agent
Inventor: RUSU VASILE
IPC: A61K31/05
Filed: 2000-01-14
Abstract: The invention relates to the pharmaceutics, in particular to the stable agents with fungicidal and bactericidal action at the internal application thereof. Summary of the invention consists in the fact that the juglone (5-hydroxy-1,4-naphthoquinone) alcoholic solution additionally contains pharmaceutically acceptable polybasic organic hydroxyacids, for example, citric, malic or tartaric acid with the following component ratio, mass %: juglone 0,18...0,22 polybasic organic hydroxyacid 0,20...1,50 ethyl alcohol the rest. The presence of the polybasic hydroxyacid into the alcoholic solution in the indicated contents ensures a higher stability in storage (1,5...2,0 years) with the maintenance of the pharmacologic activity of the agent finished form, notwithstanding the water used for dilution, owing to the capacity of the given acids type to strongly complex with the alkali-earth metals ions present into the undistilled water. Claims: 2
Patent MD-1485-F1 (MD)
Title: Process for immunomodulator preparation
Inventor: PETROV ANDREI
IPC: A61P37/00
Filed: 2000-01-31
Abstract: The invention relates to medicine, namely to the clinical immunology. Summary of the invention consists in the fact that the active substances are extracted in the boiling process from the vegetal therapeutic raw material, which includes in mass %: the milfoil grass (Achillea millefolium) 5...15, the pot marigold flowers (Calendula officinalis) 5...15, the stinging nettle leaves (Urtica dioica) - the rest, having the vegetal therapeutic raw material ratio: water 1 : 50. The boiling is carried out during 2...3 min, then the obtained extract is cooled up to 35...37 C and it is filtered. The filtrate is diluted with distilled water 1 : 10 respectively, it is filtered through kaolin, it is supplementary filtered and sterilized. The result consists in obtaining a remedy modulating the macrophage activity and proliferation of B- and T-lymphocytes. Claims: 3
Patent MD-3051-F1 (MD)
Title: Process for producing soda-lime-silicic glass
Inventor: HARCOVEI ION
IPC: C03C3/091
Filed: 2005-02-25
Abstract: The invention relates to the glass industry, in particular to processes for glass mass obtaining for producing soda-lime-silicic window glass.The process for producing glass includes calculation and preparation of the charge with removal of ferriferous impurities from the quartz sand, loading and smelting of the charge with obtaining of the glass mass, including SiO2, Na2O, CaO, Fe2O3, MgO, Al2O3 and SO3, correction of the glass mass composition with low-fusible compounds containing CaO and Na2O and decoloration thereof by introduction of oxidant mixtures and decolorizing agents.At the same time, removal of the ferriferous impurities is carried out by the magnetic separation method, the obtained final glass mass includes the afore-mentioned components in the following ratio, mass %: Na2O 13,80…14,20, CaO 7,35…7,40, MgO 4,20…4,25, Al2O3 1,60…1,70, SO3 0,35…0,40, Fe2O3 0,17…0,20, SiO2 and decolorizing agents - the rest.The decoloration of the glass mass is carried out by addition of a mixture containing 0,05 kg of polyrite and 0,33 kg of ZnO per 100 kg of glass mass.
Patent MD-3257-F1 (MD)
Inventor: BARANOV SIMION
IPC: C22B58/00
Filed: 2006-03-17
Abstract: Inventia se refera la procedeele de recuperare a galiului si arsenului din deseuri, in special din deseurile formate dupa  cresterea epitaxiala a straturilor semiconductoare. Procedeul de recuperare a galiului si arsenului din deseul format dupa cresterea epitaxiala a straturilor semiconductoare detip A3B5 include dizolvarea deseului in solutie de acid azotic 33% in acid clorhidric, modificarea pH-ului solutiei de la 0,5…1,5 pana la 3,0…4,5 prin adaugarea unei solutii de baza cu precipitarea ulterioara a arseniatului de galiu. Precipitatul obtinut se filtreaza, se spala cu apa deionizata si se usuca la temperatura de 90…120°C timp de 60 min, apoi se descompune in oxid de galiu si oxid de arsen. Arsenul este redus cu carbon din oxid la temperatura de 680…780°C, iar galiul este redus intr-un container de grafit la temperatura de 750…860°Cin flux de hidrogen. Precipitatul de arseniat de galiu poate fi obtinut si prin dizolvarea suplimentara, pana la saturatie, a plachetelor din GaAs insolutie acida obtinuta la dizolvarea deseului, iar solutia saturata se stocheaza timp de 22 de zilela temperatura camerei pentru precipitarea spontana a arseniatului, dupa care solutia cu arseniat se incalzeste pana la 60°C, in vid, timp de 2…4 ore.
Patent MD-3960-F1 (MD)
Inventor: LUPASCU GALINA
IPC: A01G7/00
Filed: 2008-05-07
Abstract: Inventia se refera la agricultura, in particular la o metoda de apreciere a pretabilitatii solului pentru cultivarea graului comun de toamna. Metoda de apreciere a pretabilitatii solului pentru cultivarea graului comun de toamna include stabilirea indicilor de atac al sistemului radicular si al bazei tulpinii plantelor de grau de catre fungi – provocatori ai putregaiului de radacina, in particular a coeficientului de corelatie a frecventei depistarii speciilor de fungi: Fusarium oxysporum var. orthoceras, F. avenaceum, F. avenaceum var.herbarum, F. semitectum, F. graminearum, F. gibbosum var. bullatum, F. moniliforme var. lactis, Sclerotium rolfsii, Aphanomyces campostilum, Alternaria alternata, Penicillium viridicatum, Epicoccum tritici la etapele timpurii, medii si tarzii de dezvoltare a plantelor, totodata se considera pretabile pentru cultivarea graului comun de toamna solurile pentru care coeficientul de corelatie stabilit constituie 0,47...0,86. Rezultatul inventiei consta in sporirea vitezei si a preciziei de identificare a solurilor pretabile pentru cultivarea  graului comun de toamna.
Patent MD-2473-G2 (MD)
Title: Method of correction of the cardiac rhythm variability
Inventor: POPOVICI MIHAIL
IPC: A61P9/06
Filed: 2003-01-31
Abstract: The invention refers to medicine, namely to cardiology.Summary of the method consists in the administration of the preparation on base of extract from Spirulina platensis CNM-CB-02(BioR) cyanobacteria strain biomass in the dose of 1,05 mg/kg with the speed of 0,07 mg/kg/min in the capacity of cardiotropic remedy.
Patent MD-2764-G2 (MD)
Title: Entomologic hepatoprotective preparation
Inventor: GHICAVÎI Victor
IPC: A61K35/64
Filed: 2004-07-28
Abstract: The invention refers to medicine, namely to hepatology.Summary of the invention consists in that the entomologic hepatoprotective preparation, obtained from insect eggs of Lepidoptera order, Lymantria kind by milling thereof up to the formation of a homogeneous mass, filtration thereof and water extraction by lyophilization, comprises the following ingredients: proteins - 412,0…628,0 mg/g, lipids - 320,0 mg/g, cholesterine - 1,2 mg/g, triglycerides - 102,5 mg/g, amylase - 59,1 IU/g, lipase - 30,0 mIU/g, antioxidants - 9,0 mg/g, essential and semi-essential amino acids - 373,5 mg/g.
Patent MD-3839-G2 (MD)
Title: Process for rapid braking of the electric tool with angle drive and device for realization thereof
Inventor: COLCEV MIHAIL
IPC: B24B23/02
Filed: 2007-05-11
Abstract: The invention relates to the electrical engineering, particularly to processes for rapid braking of the electric tool with angle drive and to devices for realization thereof.The process for rapid braking of the electric tool with angle drive consists in disconnecting the working electric tool by means of a switch, interrupting the connection of the electric tool to the electric motor, and braking of the saw blade of the electric tool is carried out by means of a friction brake gear, blocking the rotation of the drive shaft with the saw blade installed on the end thereof. Novelty consists in that for disconnection of the electric tool, as switch is used a rotary supporting handle, having three positions - one neutral, corresponding to the disconnection from the electric supply, and two operating, it is turned the handle from the neutral position to the position of rotation of the electric tool clockwise and anticlockwise. It is disconnected the electric tool by rotating the handle from the operating position to the neutral one, or by automatic release as a result of automatic rotation of the handle from the operating position to the neutral one, caused by the sudden removal of the electric tool from the cutting zone, at the simultaneous engaging into operation of the friction brake gear, as well as due to the disconnection of the driven shaft from the electric motor.The device for rapid braking of the electric tool with angle drive contains, installed into the body (1), a driven shaft (6) with saw blade (9) and a conic gearwheel (8) mounted thereon, a friction brake gear made in the form of gripping elements with the possibility of blocking the rotation of the driven shaft (6), and a switch for controlling the operation of the electric tool, including the braking process. Novelty consists in that the gripping elements of the friction brake gear are made in the form of a pair of three-tab forks (10), and on the tabs of each of the forks it is fixed a brake gear (12) with the possibility of alternate friction contact of its working surfaces with the working surfaces of the gear wheel (8) or of the brake disks (13), fixed into the body (1) and, respectively, of rotating or blocking the driven shaft (6).
Patent NL-300023-I1 (NL)
IPC: C07K16/46
Filed: 2000-11-03
Abstract: Compsn. comprises a pure human-like immunoglobulin (Ig) which (a) reacts specifically with p55 Tac protein and/or (b) inhibits binding of human interleukin-2 (IL-2) to its receptor. Also new are (1) human-like Ig having 2 pairs of light/heavy chains and able to react specifically with an epitope of a human IL-2 receptor with affinity at least 10 power 8 per mole, the chains including complementarily determg. regions (CDR's) and human-like framework regions (FR's), the CDR's being from different Ig molecules than FR's; (2) humanised Ig (hIg) which can bind to IL-2 receptors and contain at least one CDR from anti-Tac antibody in a human-like FR contg. at least one amino acid from the anti-Tac antibody; (3) nucleic acid encoding for human-like FR and at least one murine CDR, and (4) cells transfected with nucleic acid.
Patent FR-21C1028-I1 (FR)
IPC: C12N5/22
Filed: 2021-07-07
Abstract: Isolated human monoclonal antibodies which bind to and inhibit human CD20, and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced by a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Patent LU-90100-I2 (LU)
IPC: A61K31/41
Filed: 1997-07-16
Abstract: Aromatic amide derivatives of formula (I) and their salts are new. (Where R1 = aliphatic hydrocarbon optionally substituted with halogen or OH, or a cycloaliphatic or araliphatic hydrocarbon. X1 = CO, SO2, or OCO with the carbon linked to the N. X2 = aliphatic hydrocarbon (optionally substituted with OH, carboxy, NH2, guanidino, cycloaliphatic or aromatic hydrocarbon) or cycloaliphatic hydrocarbon, with a carbon of the aliphatic optionally bridged by a divalent aliphatic hydrocarbon. R2 = carboxy or its ester or amide derivative, NH2, substituted amino, formyl, acetal derivative of formyl, 1H-tetrazol-5-yl, pyridyl, OH, ether, SR, SOR, SO2R, alkanoyl, sulphamoyl, N-substituted sulphamoyl, PO2H2 or PO3H2. R = H or aliphatic hydrocarbon. X3 = hydrocarbon. R3 = carboxy, 5-tetrazolyl, SO3H, PO2H2, PO3H2 or haloalkylsulphamoyl. Rings A and B are each optionally substd. 121 compounds are specifically claimed, including (S)-N-(1-carboxy -2-methyl)-prop-1-yl) -N-pentanoyl-N- (2'-(1H-tetrazol-5-yl) biphenyl-4-ylmethyl) amine.
Patent ES-2604055-R1 (ES)
Title: Kits novedosos para la detección de trastornos del ciclo de la urea usando espectrometría de masas
Inventor: CARRARD GÉRALDINE
IPC: G01N33/68
Filed: 2016-08-31
Abstract: La presente invención se refiere a kits de exploración de recién nacidos para exploración de alto rendimiento y análisis de trastornos metabólicos usando cromatografía líquida - espectrometría de masas (LC-MS). Los trastornos metabólicos pueden ser trastornos de aminoácidos, ácidos orgánicos u oxidación de ácido graso, y particularmente trastornos o deficiencias del ciclo de la urea, hiperamonemia, hiperornitinemia-hiperamonemia-homocitrulinuria (HHH), y/o aciduria argininosuccínica.
Patent CL-2009001925-S1 (CL)
Title: Porcion interior de un cuello de botella, en el cuello vertical de seccion transversal circular se disponen cuatro nervaduras iguales de superficie convexa espaciadas en 90 grados donde cada par formado por nervaduras diametralmente opuestas, asciende helicoidal y en sentido opuesto entrelazandose.
Inventor: LONSWAY MICHAEL J
Filed: 2009-10-01
Abstract: Cuello de botella.
Patent CL-2021000755-S1 (CL)
Title: Bomba extractora de leche. (divisional solicitud 202001313)
Inventor: SANDBERG EMMA STINA KATARINA
Filed: 2021-03-25
Abstract: BOMBA EXTRACTORA DE LECHE (DIVISIONAL SOLICITUD NO. 1313-2020)
Patent SI-0881901-T1 (SI)
Title: New associations of active principles containing clopidogrel and an antithrombotic agent
Inventor: BERNAT ANDRE
IPC: A61P5/36
Filed: 1997-02-17
Abstract: PCT No. PCT/FR97/00296 Sec. 371 Date Aug. 12, 1998 Sec. 102(e) Date Aug. 12, 1998 PCT Filed Feb. 17, 1997 PCT Pub. No. WO97/29753 PCT Pub. Date Aug. 21, 1997The invention relates to a pharmaceutical composition containing an association of active principles, wherein the active principles are clopidogrel and aspirin, each constituent being present in a free form or in the form of a pharmaceutically acceptable salt.
Patent TR-199701705-T1 (TR)
Inventor: GROTE MARTIN ROGER
IPC: C12P7/64
Filed: 1996-06-14
Abstract: Mevcut bulus, trigliserid yaglarin islenmesini katalize etmek için, enzimleri hareketsiz hale getirme islemi ve hareketsiz enzimleri kullanmayla ilgilidir.
Patent TR-199903003-T1 (TR)
Inventor: CECCHERINI CARLO
IPC: G01C17/38
Filed: 1999-03-25
Abstract: Burada tanimlanan bulus: yerkürenin kuzey manyetik kutup yönünü belirleyebilme kapasitesine sahip en az iki sensör ünitesi; ayni zamanda hem yerkürenin manyetik kuzey kutup yönüne hem de cografi kuzey kutup yönüne göre pozisyonu belirleyebilme kapasitesine sahip en az bir sensör; yerel yerkürenin manyetik alanindan kaynaklanan, söz konusu sistemdeki tüm sensör ünitelerini etkileyen hatalari dengeleme kapasitesinden olusan bölmeli tasarima sahip bir baslik  sistemi ile ilgilidir. Bu bulus özellikle baslik açilarini ölçen, ölçüm aletlerinin teknik  alanina siniflandirilabilir. Bu bulusun uygulama alani baslica deniz samandiralari, deniz alti gemileri ve yedeklemeli sensör dizileri gibi bölmeli tasarimli deniz yüzeyi ve deniz alti sistemlerinin baslik açilarinin ölçümü teskil eder.
Patent AT-E231535-T1 (AT)
Inventor: STECKELBERG JOACHIM DR
IPC: C09B62/51
Filed: 2000-02-26
Granted: 2003-02-15
Abstract: The present invention comprises a dye mixture comprising one or more, such as one, two or three, disazo dyes conforming to the general formula (1), one or more, such as one, two or three, monoazo dyes conforming to the general formula (2), and one or more, such as one, two or three dyes of the general formulae (3) and (4) wherein the formulae (1) to (4) are defined as given in claim 1, a method for its preparation and a process for dyeing hydroxy- and/or carboxamido containing fiber material in which a inventive dye is applied to the material.
Patent AT-E333619-T1 (AT)
Inventor: NAD FERENC
IPC: F16L3/237
Filed: 2000-05-13
Granted: 2006-08-15
Abstract: The cable clamp has a central part for applying to a cable and two spring ends for latching in mutually parallel toothed walls of the component. The cable clamp is formed of a central pressure element (11) and two laterally connecting curved spring elements (19) in the form of S-shaped double curves. The double curves can be hairpin-shaped with opposed apices (14).
Patent AT-E518118-T1 (AT)
Inventor: DAVIES LAWRENCE
IPC: G01F1/84
Filed: 2000-11-08
Granted: 2011-08-15
Abstract: The Coriolis measurement tube (1) is made of ceramic.
Patent AT-E223256-T1 (AT)
Inventor: EBEL ACHIM
IPC: C08J11/00
Filed: 2000-12-15
Granted: 2002-09-15
Abstract: The invention relates to a device for purifying and/or decontaminating polyester, in particular polyethylene terephthalate (PET). Said device has a rotary kiln (1), which is at least partially heated and fed with a mixture of polyester and an alkaline material, for carrying out a saponification reaction in the mixture. The invention is characterised in that the rotary kiln (1) contains a weir-type element (22), which closes at least part of the interior (5) of said kiln (1).
Patent AT-E305866-T1 (AT)
Inventor: DIETZEL BERND
IPC: B60T1/087
Filed: 2000-12-22
Granted: 2005-10-15
Abstract: The return temperature of the cooling medium in the region of the outlet from the engine's braking unit(3) is calculated from an amount of cooling medium to the braking unit at least indirectly characterizing the supply temperature and the energy introduced into the cooling medium fluid of the braking unit during operation.  An Independent claim is included for a control and regulating system(17) for a drive train which has an input connected to means to at least indirectly record the supply temperature in the cooling circuit to the braking unit, and an output connected to a control unit to control the braking moment of the braking unit. A computing device determines the energy introduced into the cooling medium from the braking unit during operation. An Independent claim is included for a system which has an additional computing device to calculate water supply temperature.
Patent AT-E409947-T1 (AT)
Inventor: MIKOSHIBA SATOSHI
IPC: H01L31/042
Filed: 2000-09-22
Granted: 2008-10-15
Abstract: The present invention provides an electrolyte composition (10), comprising an electrolyte containing at least one kind of an imidazolium salt selected from the group consisting of 1-methyl-3-propyl imidazolium iodide, 1-methyl-3-isopropyl imidazolium iodide, 1-methyl-3-butyl imidazolium iodide, 1-methyl-3-isobutyl imidazolium iodide and 1-methyl-3-sec-butyl imidazolium iodide, a halogen-containing compound dissolved in the electrolyte, and a compound dissolved in the electrolyte and containing at least one element selected from the group consisting of N, P and S, the compound being capable of forming an onium salt together with the halogen-containing compound. <IMAGE>
Patent AT-E336780-T1 (AT)
Inventor: UNNO TAKAHIRO
IPC: H03M7/30
Filed: 2000-11-22
Granted: 2006-09-15
Abstract: A decoder for code excited LP encoded frames with both adaptive and fixed codebooks; erased frame concealment uses muted repetitive excitation, threshold-adapted bandwidth expanded repetitive synthesis filter, and jittered repetitive pitch lag. <IMAGE>
Patent AT-E295575-T1 (AT)
Inventor: PERROUX FRANCOIS
IPC: G06F17/21
Filed: 2000-02-29
Granted: 2005-05-15
Abstract: A computer system operation method for allowing a user to work on interrelated documents includes forming groups of software tools. Different groups of software tools are used to perform different tasks on documents in a software system. Documents in the software system have different document types. The document types are functionally associated with the different groups of software tools. The method monitors a user's selection of a second group of software tools, when the user is using a first workbench to work on data contained in a first document. The method invokes a second document, upon the user's selection of a second group of software tools. The second document is of a document type that is associated with the second workbench. The method may include generating referencing data, upon the invocation of the second document, and storing the referencing data in the first document, where the referencing data refer to all or part of the data in the second document. The method may include generating referencing data, upon the invocation of the second document, and storing the referencing data in the second document, where the referencing data refer to all or part of the data in the first document. <IMAGE>