baber/WOPTO huggingface dataset:
Patent AU-686911-B2 (AU)
Title: Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides
Inventor: JONES DAVID S
IPC: C07F9/24
Filed: 1995-12-20
Granted: 1998-02-12
Abstract: Phosphoramidites of the formula <CHEM> where R is a base-labile protecting group, R<1> and R<2> are individually alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, or aryl of 6 to 20 carbon atoms or are joined together to form with the nitrogen atom a cyclic structure of 4-7 carbon atoms and 0 to 1 annular chalcogen atoms of atomic number 8 to 16, G is a hydrocarbylene group of 1 to 20 carbon atoms and Z is a hydroxy-protected vicinal diol group bound to G by one of the vicinal diol carbon atoms or a disulfide group and bound to G by one of the sulfur atoms of the disulfide group, with the proviso that G is of at least 4 carbon atoms when Z is said disulfide group are used in conventional automated oligonucleotide synthesis to introduce a functional aldehyde or thiol group on the 5 min end of the oligonucleotide to thereby provide a reactive site on the oligonucleotide that may be used to conjugate the oligonucleotide to molecules that contain a free amino group or an electrophilic center reactive with a thiol group.
Patent AU-578290-B2 (AU)
Title: Isomerization of halogenated thiophenes
Inventor: EICHLER KLAUS
IPC: C07D333/28
Filed: 1985-05-24
Granted: 1988-10-20
Abstract: The invention relates to a process for the isomerization of halogenated thiophenes on zeolite catalysts. In this manner, in particular, 2-chlorothiophene is isomerized to 3-chlorothiophene and 2-bromothiophene is isomerized to 3-bromothiophene. Particularly suitable zeolites are synthetic zeolites of the pentasil, mordenite or faujasite type in their acid form.
Patent AU-765257-B2 (AU)
Title: Polyketides and their synthesis
Inventor: LEADLAY PETER FRANCIS
IPC: C07K19/00
Filed: 1999-06-29
Granted: 2003-09-11
Abstract: A polyketide synthase ("PKS") of Type I is a complex multienzyme including a loading domain linked to a multiplicity of extension domains. The first extension module receives an acyl starter unit from the loading domain and each extension module adds a further ketide unit which may undergo processing (e.g. reduction). We have found that the Ksq domain possessed by some PKS's has decarboxylating activity, e.g. generating (substituted) acyl from (substituted) malonyl. The CLF domain of type II PKS's has similar activity. By inserting loading modules including such domains into PKS's not normally possessing them it is possible to control the starter units used.
Patent AU-628429-B2 (AU)
Title: Travelling gear for track vehicles
Inventor: AHLBORN GUNTER
IPC: B29C65/22
Filed: 1989-11-27
Granted: 1992-09-17
Abstract: The invention relates to running gear for railway vehicles having a low-lying loading bridge, consisting of at least two sets (4) of wheels with a small axle base and a running gear frame consisting of lateral faces (1) and crossmembers (2) between two axles in each case, the sets (4) of wheels being braced in the running gear frame via the axle bearings (3), and the running gear being connected with false pivot to the vehicle frame solely via a bearing leaf spring (10) and a shackle suspension (11), each lying laterally lengthwise. 
<??>The object of the invention was to improve the rolling characteristics in this running gear, to optimise the running behaviour on straight track and in bends with the arrangement of the required transverse clearance of the running gear and to make it more favourable by the use of long shackles. The power transmission from the loading bridge via the bearing leaf spring (10) into the running gear was to be improved. 
<??>This object is achieved by the fact that the bearing leaf springs (10) are arranged on spring brackets (5) arranged on the outside on the lateral faces (1) of the running gear frame laterally between the clearance gauge (6) and the loading space (8) of the vehicle and above the wheels. 
<IMAGE>
Patent AU-689022-B2 (AU)
Title: Seamless molded skirt and process
Inventor: SCHELIGA WERNER
IPC: B29C45/44
Filed: 1996-02-08
Granted: 1998-03-19
Abstract: A molded cap for sealing a container, and having a core-profiled internal skirt portion is injection molded within a seamless annular cavity mold, wherein segmentation of the interior core die portion bearing the internal form such as a screw thread form for the inside of the cap skirt, permits its inward withdrawal clear of the cap after completion of the injection cycle. Due to the seamless mold cavity the cap has no externally visible mold witness lines along its skirt. The molded cap contracts radially as it cools within the mold, permitting molded parts and decorative features that are on or in the skirt face to withdraw radially inwardly from the mold surfaces, such that the cap can be ejected clear from the mold without damage to fine detailed or hang-up on undercuts into the mold skirt face.
Patent AU-589922-B2 (AU)
Title: Absorption article such as a diaper or a sanitary napkin, and a method for the manufacture thereof
Inventor: TERNSTROM MAJ INGELA
IPC: A61F13/15
Filed: 1985-11-26
Granted: 1989-10-26
Abstract: The present invention relates to absorption articles such as diapers or sanitary napkins comprising partly a liquid permeable first outer layer (1) and a preferably liquid impermeable second outer layer (2) applied to either side of an absorption body (3) encased therein; partly elastic members applied under tension and intended for bringing the edge portions of said article into tightly sealing contact with the body of the wearer. The primary distinguishing feature of the inventive article is that the elastic members (24, 25) are comprised in a network.
Patent AU-770966-B2 (AU)
Title: Isocyanate composition containing a masked and an unmasked isocyanate and their use for coating
Inventor: BERNARD JEAN-MARIE
IPC: C08G18/80
Filed: 1999-07-28
Granted: 2004-03-11
Abstract: The invention concerns an isocyanate composition useful for applying powder paints. Said composition is characterised in that it contains a masked isocyanate compound and an unmasked cycloaliphatic isocyanate compound. The invention is applicable in the chemistry of paints.
Patent AU-645006-B2 (AU)
Title: Disposable absorbent article having elastically extensible topsheet
Inventor: FREELAND MARY ELAINE
IPC: A61F5/44
Filed: 1990-03-08
Granted: 1994-01-06
Abstract: A disposable absorbent article, such as a diaper, is disclosed. The topsheet of the diaper is elastically extensible and provides a relatively low contact pressure against the skin of the wearer at relatively high elongations. This arrangement provides a diaper topsheet which can be elongated to conform to the shape of the wearer without causing undue discomfort or irritation. The relatively low ultimate contact pressure at relatively high elongation may be accomplished either through a low contact force differential material, or through a material which exhibits stress relaxation over a relatively short period of time. The topsheet may be a laminate having one elastomeric lamina and an inelastic lamina. Also disclosed is a method for making such a laminate.
Patent AU-583341-B2 (AU)
Title: Cassette holder in recording and reproducing apparatus for magnetic tape cassette having underside-covering sliding shutter member
Inventor: EMORI MASASHI
IPC: G11B15/675
Filed: 1986-01-22
Granted: 1989-04-27
Abstract: A lock release mechanism is provided in a cassette holder for magnetic tape cassettes. The magnetic tape cassettes have a pivotal closure lid (35) pivotably secured to opposite edges of a casing for movement between a closed position, in which the front opening of the casing through which a magnetic tape can be extracted for loading onto a rotary head is sealed while not in use, and an open position, in which the closure lid is pivoted away from said opening to allow access to the tape while in use. The cassette (28) also has a sliding closure member (36) slidably mounted on one face of the casing and co-operating with the aforementioned pivotal closure lid (35). The sliding closure member (36) is held in its closed position while the pivotal closure lid (35) is In its closed position to cover a bottom spacing through which a device constituting part of a tape handling mechanism may be inserted, and in its open position while the pivotal closure lid (35) is in its open position to allow said device of the tape handling mechanism to engage the casing through the bottom spacing and extract the tape for loading onto the rotary head. The sliding closure member (36) is retained in its closed and open positions by means of a lock member (55). The lock release mechanism is provided in a cassette holder of the recording and reproducing apparatus and comprises a projection means (9) having a portion (9b) which releases the lock member (55) to allow movement of the sliding closure member (36) from the closed position to the open position when the magnetic tape cassette (28) is inserted into the cassette holder for loading and a portion (9a) which releases the lock member (55) to allow movement from the open position to the closed position when the magnetic tape cassette (28) is ejected.
Patent AU-628533-B2 (AU)
Title: Interface between a system control unit and a service processing unit of a digital computer
Inventor: EVANS MICHAEL B
IPC: G06F13/42
Filed: 1990-04-27
Granted: 1992-09-17
Abstract: A computer system includes a plurality of central processing units (CPUs), a main memory, a system control unit (SCU) for controlling the transfer of data between the CPUs and the main memory, and a service processing unit (SPU) to interface the computer system with the outside world, such as an operator console. The method used for interfacing the SPU and SCU includes delivering a BUFFER FULL handshaking signal from the SPU to the SCU in response to the SPU receive buffer having data contained therein and being unavailable to receive data. The SCU responds to the absence of the BUFFER FULL handshaking signal by delivering a TRANSMIT FRAME handshaking signal to the SCU. A preselected duration of time after delivering the transmit frame, the SCU delivers the actual data in a series of fourteen consecutive clock cycles. Further, the method for delivering data from the transmit buffer of the SPU to a receive buffer of the SCU includes delivering a BUFFER REQUEST handshaking signal from the SPU to the SCU in order to determine if a buffer is currently available in the SCU. When a receive buffer grant becomes available in the SCU, a buffer grant handshaking signal is delivered to the SPU. The SPU responds by delivering the actual data in fourteen consecutive clock cycles.
Patent AU-687025-B2 (AU)
Title: Use of macrolides for the treatment of cerebral ischemia
Inventor: KELLY JOHN S
IPC: A61P9/08
Filed: 1993-12-24
Granted: 1998-02-19
Abstract: PCT No. PCT/JP93/01886 Sec. 371 Date Jun. 29, 1995 Sec. 102(e) Date Jun. 29, 1995 PCT Filed Dec. 24, 1993 PCT Pub. No. WO94/14443 PCT Pub. Date Jul. 7, 1994The present invention relates to a new use of macrolide compounds of the formula (I):    <IMAGE>  (I)  wherein each symbol is as defined in the specification, for preventing or treating cerebral ischemic disease, such as, brain damage caused by ischemia, such as cerebral infarction. So, they are useful when the following diseases or injury occur. That is, head injury, hemorrhage in brain such as subarachnoid hemorrhage or intracerebral hemorrhage, cerebral thrombosis, cerebral embolism, cardiac arrest, stroke, transient ischemic attacks (TIA), hypertensive encephalopathy and so on.
Patent AU-692141-B2 (AU)
Title: Disposable absorbent article having a mechanical fastening system
Inventor: GOULAIT DAVID JOSEPH KENNETH
IPC: A61F13/72
Filed: 1993-12-08
Granted: 1998-06-04
Abstract: The invention is an absorbent article such as a sanitary napkin, comprising a main body portion which is divided into a first half and a second half by a principle transverse centerline, and an oriented hook fastening material joined to the first half and second half of the main body portion. The oriented hook fastening material is oriented in a direction having a vector component perpendicular to the principle transverse centerline of the main body portion. In an alternate embodiment of the present invention, the disposable absorbent article will have side flaps joined to the main body portion and an oriented hook fastening material joined to the side flaps. In another alternate embodiment of the present invention, the disposable absorbent article will have a combination of a pressure sensitive adhesive and an oriented hook fastening material joined to the main body portion.
Patent AU-669052-B2 (AU)
Title: Security printing machine
Inventor: WYSSMUELLER PHILIPPE
IPC: B65C9/18
Filed: 1994-04-08
Granted: 1996-05-23
Abstract: Machine for security printing on security papers, particularly bank notes, comprising a paper-feed device (1), a paper-transportation device and a unit (19) for applying optically variable images supplied by at least one tape which is brought into contact with the paper such that these images are applied at specific locations on the paper corresponding to printing (impressions) on security papers. The application unit (19) includes at least one activator roll (11) interacting with a pressure roll (20) and between which the paper passes through. The tape is mounted between two reels which are arranged in a sector of the applicator roll (11) and the tape passes along a generatrix of the said applicator roll, perpendicularly to the path of the paper, under the action of a servomotor acting intermittently at each application step. <IMAGE>
Patent AU-641673-B2 (AU)
Title: Bispecific reagents for aids therapy
Inventor: FANGER MICHAEL W
IPC: C07K16/10
Filed: 1990-06-29
Granted: 1993-09-30
Abstract: Bispecific molecules which react both with the high-affinity Fc gamma receptor of human effector cells and with a virus or virus component are disclosed. Binding of the molecules to the Fc receptors found on effector cells is not blocked by human immunoglobulin G. The molecules are useful for targeting human effector cells (e.g. macrophages) against a viral target (e.g. HIV or BIV-infected cell). For this purpose, bispecific molecules can be constructed containing the binding region derived from an anti-Fc gamma  receptor antibody and the CD4 molecule or CD4 binding domain of the envelope glycoprotein gp120 of BIV. Alternatively, bispecific antibodies or heteroantibodies can be constructed containing the binding region derived from an anti-Fc receptor antibody and the binding region of HIV-specific antibody such as anti-gp120 antibody. Targeted effector cells can be used to kill virus by cell mediated antibody dependent cytolysis.
Patent AU-652124-B2 (AU)
Title: Stabilized protein or peptide conjugates
Inventor: NYGREN PER-AKE
IPC: A61K47/48
Filed: 1990-07-31
Granted: 1994-08-18
Abstract: A process for extending the half-life in vivo by a biologically active protein or peptide, characterized by covalently coupling said protein or peptide to a polypeptide fragment capable of binding to a serum protein, whereby when administering the resulting protein or peptide congugate its binding to the serum protein results in extended biological activity; the use of the protein or peptide conjugate above for manufacturing a medicament which, when administered to a mammal including man, shows extended half-life in vivo; and a method of therapeutic or prophylactic treatment.
Patent AU-723350-B2 (AU)
Title: Chimeric proteins for use in transport of a selected substance into cells
Inventor: HEARTLEIN MICHAEL W
IPC: A61K39/395
Filed: 1996-06-03
Granted: 2000-08-24
Abstract: Chimeric proteins useful in transporting a selected substance present in extracellular fluids, such as blood or lymph, into cells; quantitative assays for the selected substance using chimeric proteins; DNA encoding the chimeric proteins; plasmids which contain DNA encoding the chimeric proteins; mammalian cells, modified to contain DNA encoding the chimeric proteins, which express and, optionally, secrete the chimeric proteins; a method of producing the chimeric proteins; a method of isolating the chimeric proteins; a method of using the chimeric proteins to assay the selected substance; and a method of reducing extracellular levels of the selected substance through administration of the chimeric protein, which results in transport of the selected substance into cells.
Patent AU-714001-B2 (AU)
Title: Moulding process for producing a vehicle seat
Inventor: BURCHI CHARLES R
IPC: B29C44/08
Filed: 1994-02-25
Granted: 1999-12-16
Abstract: A passenger seat includes a frame element molded from relatively high density foam and, optionally, one or more pelvic support elements. The frame element and pelvic support elements are molded into a seat body of relatively lower density foam to which a trim cover is applied. In one embodiment, the frame element and the pelvic support elements are integrally molded and a vehicle anchorage means in embedded into the integral element and in a second embodiment the vehicle anchorage means is embedded in the frame element which may be molded separately from the pelvic support element to which it is connected prior to molding of the foam body.
Patent AU-767141-B2 (AU)
Title: Null IGF for the treatment of cancer
Inventor: MASCARENHAS DESMOND
IPC: A61K38/27
Filed: 1999-09-29
Granted: 2003-10-30
Abstract: New methods for the treatment of cancer are provided. Null IGF(IGF variants with reduced receptor binding) is administered to subjects having cancer, thereby alleviating the symptoms of the cancer.
Patent AU-597908-B2 (AU)
Title: A protein reagent having the ability to bind tissue plasminogen activator in its two chain form and/or its single chain form
Inventor: DOWDLE EUGENE BERNARD DAVEY
IPC: A61K36/48
Filed: 1986-10-03
Granted: 1990-06-14
Abstract: The present invention provides a protein reagent having the ability to bind to tissue plasminogen activator (tPA) and/or pro-tPA reversibly comprising a Kunitz-type proteinease inhibitor having a molecular weight in the range l7-23,000 daltons, being non-cytotoxic, having the ability to inhibit tPA, pro-tPA and trypsin, but not urokinase or thrombin, having two disulphide bridges and being substantially free from proteases. Such an inhibitor may be derived from seeds of an Erythrina species.
Patent AU-780621-B2 (AU)
Title: Processes for the preparation of oxo-oxazoline or alloamino acid derivatives
Inventor: KOBAYASHI MAKOTO
IPC: C07K5/078
Filed: 2000-08-25
Granted: 2005-04-07
Abstract: A method for producing a compound represented by the general formula (I-A) or the general formula (I-B), comprising the following step: <CHEM>   <CHEM> wherein R<1> is an optionally substituted lower alkyl, and the like; R<2> is a lower alkyl or an optionally substituted aralkyl, and the like; R<3> is a lower alkyl, characterized in that a compound represented by the general formula (II-A) or the general formula(II-B) is treated with thionyl chloride.
Patent AU-543698-B2 (AU)
Title: Livestock obstetrics instrument
Inventor: UHLMANN GEORG
IPC: A61D1/08
Filed: 1981-04-07
Granted: 1985-04-26
Abstract: An apparatus is provided for livestock obstetrics. The apparatus bears against the body of the dam, a leg sling is placed on the offspring, and two slides can progressively be moved along a rod to tension the leg sling. To move the slides, a tensioning lever is hinged to one slide, and an intermediate lever is hinged at a different location to the one slide and is also hinged to the other slide. The intermediate lever is in two parts normally held together by spring tension, but if an excess load is applied by the tensioning lever the spring tension is overcome and the parts separate, whereby maximum permissible tension between dam and offspring is not exceeded. To completely release the pull on the offspring, the tensioning lever can be moved to release both slides.
Patent AU-600479-B2 (AU)
Title: Solid state electricity meter display
Inventor: STEVENS RAY
IPC: G01R21/133
Filed: 1987-04-01
Granted: 1990-08-16
Abstract: In a solid state electricity meter, a display (16) consisting of a number of juxtaposed display elements provides, in a vector form, an indication of the direction and range of power flow in the line being measured. Circuitry for driving the vector display comprises a first memory storing a plurality of power measurement references and a second memory storing corresponding vector symbols. A microprocessor (50) compares each power measurement with the references stored in the first memory to determine the range of the power measurement and, in response, reads the corresponding vector symbol from the second memory to drive the display (16).
Patent AU-573126-B2 (AU)
Title: 1,4-dihydro-4-oxoquinoline-3-carboxylic acids
Inventor: GROHE KLAUS
IPC: A23K20/195
Filed: 1987-04-09
Granted: 1988-05-26
Abstract: 1. Claims (for the Contracting States : AT, BE, CH, DE, FR, GB, IT, LI, NL, SE) Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acids of the formula I  see diagramm : EP0078362,P10,F3  in which R denotes hydrogen, methyl, ethyl or beta-hydroxyethyl, and their pharmaceutically usable acid addition salts, alkali metal salts and hydrates, except 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acid and its hydrochloride, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (4-methylpiperazino)-quinoline-3-carboxylic acid and 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (4-ethylpiperazino)-quinoline-3-carboxylic acid hydroiodide. 1. Claims (for the Contracting State LU) 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acids of the formula I  see diagramm : EP0078362,P11,F3  in which R denotes hydrogen, methyl, ethyl or beta-hydroxyethyl, and their pharmaceutically usable acid addition salts and hydrates.
Patent AU-705157-B2 (AU)
Title: Process for the preparation of materials with a high content of long chain polyunsaturated fatty acids
Inventor: CAIN FREDERICK WILLIAM
IPC: A23L33/115
Filed: 1996-11-12
Granted: 1999-05-13
Abstract: A process for preparing a material B comprising geometrical isomers L1 and L2 of conjugated linoleic acid moieties in a specific weight ratio of XB wherein a material A selected from free fatty acids, mono-, di- or tri-glycerides, phospholipids, alkyl esters or wax-esters containing at least 5 weight % of L1 and L2 are subjected to enzymatic conversion using an enzyme that can discriminate between L1 and L2 so that the original weight ratio of L1 to L2 of XA in the starting material is increased to XB where XB is equal to or greater than 1.1 XA. Advantageously, the isomers L1 and L2 are cis9, trans11 and trans10, cis12 linoleic acid or vice versa. The enzyme is advantageously a lipase obtained from Geotrichum candidum or Candida rugosa or a phospholipase. The starting material A may be, for example, a fish oil or vegetable oil. The resulting products may be blended with a complementary fat and may be used as foods or food supplements or in pharmaceutical compositions.
Patent AU-643276-B2 (AU)
Title: Apparatus and method for respired gas collection
Inventor: DERRICK STEVEN J
IPC: A61M16/06
Filed: 1991-03-22
Granted: 1993-11-11
Abstract: Apparatus and method for selective, separate or simultaneous collection and analysis of nasal gases and oral gases, and mixtures thereof, respired by a patient, with optional simultaneous delivery to the patient of selected inhalant gases. The apparatus comprises a nasal gas cannula and an oral gas capture member constructed and arranged to avoid or minimize contact with the patient's mouth and other facial surfaces.