baber/WOPTO huggingface dataset:
Patent WO-2021081257-A1 (WO)
Title: Artificial intelligence for personalized oncology
Inventor: HASSAN-SHAFIQUE KHURRAM
IPC: G16H30/20
Filed: 2020-10-22
Abstract: Techniques performed by a data processing system for operating a personalized oncology system herein include accessing a first histopathological image of a histopathological slide of a sample taken from a first patient; analyzing the first histopathological image using a first machine learning model configured to extract first features from the first histopathological image; searching a histological database that includes a plurality of second histopathological images and corresponding clinical data for a plurality of second patients to generate search results; analyzing the plurality of third histopathological images and the corresponding clinical data associated with the plurality of third histopathological images using statistical analysis techniques to generate associated statistics and metrics associated with mortality, morbidity, time-to-event, or a combination thereof for the plurality of third patients associated with the third histopathological images; and presenting an interactive visual representation of the associated statistics and metrics including information for the personalized therapeutic plan for treating the first patient.
Patent WO-2021091955-A1 (WO)
Title: Récipient et procédé de fabrication
Inventor: KELLEY PAUL
IPC: B29C49/42
Filed: 2020-11-04
Abstract: La présente invention concerne un procédé de fabrication d'un récipient (10) qui consiste à injecter un premier matériau (60) dans un premier moule (50) pour former une partie supérieure (25) d'une préforme (18). Le premier matériau (60) et un second matériau (62) sont injectés dans le premier moule (50) pour former une partie inférieure (35) de la préforme (18). La préforme (18) est disposée dans un second moule (50). La préforme (18) est moulée par soufflage en un récipient fini (10).
Patent WO-2021092596-A1 (WO)
Inventor: WARD PHILIP
IPC: G02B6/44
Filed: 2020-11-09
Abstract: A carriage is configured to be mounted in a fiber distribution cabinet. The carriage includes a carriage body having a front end, a rear end, a first side, a second side, and a back wall cooperating to define a cavity. A top wall is disposed at the front end of the carriage body, and a plurality of side walls extending from the back wall to the top wall. The top wall, the side walls, and the back wall define a plurality of openings at the front end of the carriage body. The top wall includes a plurality of slots, and each the plurality of slots being associated with a respective one of the plurality of openings. The plurality of openings are sized and configured to receive a fiber optic component.
Patent WO-2021113569-A1 (WO)
Inventor: KRASILEVA KSENIA
IPC: C12N15/82
Filed: 2020-12-04
Abstract: L'invention concerne des procédés d'identification de résidus d'acides aminés de NRS qui sont susceptibles d'être impliqués dans l'immunité d'agents pathogènes. L'invention concerne également des procédés de modification de l'immunité des plantes qui consistent à modifier (par ex., substituer, supprimer ou ajouter un acide aminé avant ou après) un ou plusieurs des résidus d'acides aminés qui ont été identifiés comme étant susceptibles d'être impliqués dans l'immunité d'agents pathogènes.
Patent WO-2021126746-A1 (WO)
Title: Corrosion inhibitors for a refinery
Inventor: NAGU MUTHUKUMAR
IPC: C07C229/52
Filed: 2020-12-14
Abstract: Corrosion inhibitor compositions and methods for inhibiting corrosion on a metal surface exposed to a hydrocarbon fluid are provided. The corrosion inhibitor composition can comprise 2-aminoterephthalic acid, dimethyl sulfoxide and heavy aromatic naphtha (HAN). In another embodiment, the composition can comprise 4-methylamino benzoic acid or 4-methylsulfonyl benzoic acid, N-methyl pyrrolidone, and HAN. In the method, a corrosion inhibitor composition comprising 2-aminoterephthalic acid, 4-methylamino benzoic acid, or 4-methylsulfonyl benzoic acid can be added to a hydrocarbon fluid exposed to the metal surface. The corrosion can be caused by naphthenic acid.
Patent WO-2021183201-A1 (WO)
Title: Method of dyeing textiles lignin
Inventor: AGARWAL DHRUV
IPC: D01G11/00
Filed: 2020-12-18
Abstract: Dye baths including an aqueous solution including lignin in a range of 10% to 30% by weight of the aqueous solution. In addition, methods of dyeing fibers, yarns, textiles, or garments with an aqueous solution including 10% to 30% lignin by weight is disclosed. Further, methods of dyeing a fabric including preparing a first dye bath including an aqueous solution having lignin in a range of 10% to 30% by weight of the aqueous solution and passing a fabric through the first dye bath such that the fabric pics up lignin to dye the fabric is disclosed.
Patent WO-2021173219-A1 (WO)
Inventor: AHER ANKUR ANIL
IPC: G06F16/957
Filed: 2020-12-23
Abstract: A system for managing media content annotations is configured to generate annotations having a format similar to a title and tailored to a user profile. The system identifies a media content item, a user entity, and associated metadata, and determines a title corresponding to the media content item. The system generates a title template based on the title and based on metadata associated with the media content item. Based on the title template and user profile information, the system generates an annotation, which is linked to the media content item. The system may generate more than one annotation, and then select an annotation for a given user. The annotation may include keywords or entities that are included in, linked to, or otherwise associated with the user profile information. The system outputs, or generates for output, a display that includes a representation of the media content item and the annotation.
Patent WO-2021141787-A1 (WO)
Title: Method of fabricating metal-nitride vertically aligned nanocomposites
Inventor: WANG HAIYAN
IPC: C23C14/06
Filed: 2020-12-26
Abstract: A method of the fabricating a metal-nitride vertically aligned nanocomposites is disclosed which includes applying a pulsed laser onto a composite target, the composite target including a two-phase metal-nitride plasmonic nanostructure, depositing adatoms of the composite target onto a substrate, and nucleating metal over the substrate and growing metal and nitride thereover until a predetermined size of vertically aligned metal nitride nanocomposite is achieved including metal nanorods embedded in nitride.
Patent WO-2021154446-A1 (WO)
Title: Earth plant compostable biodegradable substrate and method of producing the same
Inventor: EDWARD SHOWALTER
IPC: C08K3/26
Filed: 2020-12-31
Abstract: An earth plant-based compostable biodegradable composition for the formation of a bioplastic and method of producing said resin, the composition comprising: about 17.5 to 45% ethanol- based green polyethylene by weight, about 20 to 25% calcium carbonate by weight, about 2 to 12% hemp hurd or soy protein by weight, about 32 to 45% starch by weight, and about 0.5 to 1% biodegradation additive by weight to enable biodegradation and composting of the bioplastic; wherein the composition is produced by first mill grinding the ethanol-based green polyethylene, calcium carbonate, hemp hurd or soy protein, starch and the biodegradation additive into fine powders, then mechanically mixing the fine powders one by one into a final mixture for about 5- 25 minutes at a time, dry and without heat, and then heating the final mixture to about 220 to 430 degrees Fahrenheit.
Patent WO-2021127698-A1 (WO)
Title: Methods and systems for local to global frame transformation
Inventor: BOLDUC ANDREW PHILLIP
IPC: G01S7/497
Filed: 2020-12-17
Abstract: A method includes measuring, with a sensor, a distance between a vehicle in a field of view of the sensor and the sensor, receiving a V2X communication from the vehicle indicative of the positional information of the vehicle, synchronizing the measurement from the sensor with the positional information received from the vehicle, and, using the synchronized data, determining an angular offset of the sensor, the angular offset being the angle between an azimuth of the sensor and the North direction.
Patent WO-2021162808-A1 (WO)
Title: Methods of treating pseudobulbar affect and other emotional disturbances
Inventor: MACALLISTER THOMAS
IPC: A61K31/506
Filed: 2021-01-08
Abstract: The invention is based on the discovery that rho kinase inhibitors can be used to treat pseudobulbar affect (PBA). The inventive methods relate to the use of rho kinase inhibitors in the treatment of patients with PBA. Preferred aspects of the invention contemplate treating PBA due to dementia, especially cortical dementia, such as AD, FTD and cortical vascular dementia.
Patent WO-2021142204-A1 (WO)
Title: Hammer
Inventor: HERRITZ DEVIN W
IPC: B25D1/14
Filed: 2021-01-08
Abstract: A tool, such as a hammer, including a surface to strike objects, such as nails, and a mechanism to facilitate the removal of objects, such as staples that have been inserted into wood. In one embodiment the mechanism includes a recess in the hammerhead body and a projection that extends above the recess.
Patent WO-2021158864-A1 (WO)
Title: Modified metal foil capacitors and methods for making same
Inventor: SHAFIEI MEHDI
IPC: H01G9/045
Filed: 2021-02-05
Abstract: Disclosed is a metal foil capacitor, preferably an aluminum capacitor, comprising a modified metal foil comprising a base metal, preferably an aluminum foil. The modified metal foil capacitor may satisfy at least two of the following conditions: (a) the modified metal foil has a surface area of at least 10 times greater than an unmodified metal foil; (b) the modified metal foil has a dielectric constant (k) of at least 5; (c) the modified metal foil has a thickness of at least 1 micron; and/or (d) the modified metal foil comprises at least one metal in addition to the base metal, wherein the at least one metal is present in an amount of at least 0.01 wt.% based on the total weight of the modified metal foil. Methods for preparing the metal foil capacitor are also disclosed.
Patent WO-2021201987-A1 (WO)
Inventor: LI XIANG
IPC: G06F8/41
Filed: 2021-02-09
Abstract: The present disclosure relates to devices and methods for transforming program source code using a rematerialization operation. The devices and methods may identify at least one hot spot with high register pressure in a program source code for an application and identify a plurality of live variables within the at least one hot spot. The devices and methods may group the plurality of live variables by a basic block that has contained a define or single use of the plurality of live variables. The devices and methods may build a directed acyclic graph (DAG) for each basic block that has a grouped plurality of live variables. The devices and methods may save the DAG as a candidate instruction to move in the program source code and may generate transformed program source code for the application by moving the candidate instruction.
Patent WO-2021188456-A1 (WO)
Title: Enasidenib glycosides and methods of treating diseases associated with isocitrate dehydrogenase (idh) dysfunction
Inventor: DING SHENG
IPC: A61K47/68
Filed: 2021-03-15
Abstract: Enasidenib glycosides and methods of making enasidenib glycosides are disclosed. Glycosyl transferases catalyze addition of one or more monosaccharides to enasidenib to yield enasidenib glycosides. Suitable monosaccharides can be in the L- or D- configuration and typically have 5, 6, or 7 carbons. Suitable monosaccharides include allose, apiose, arabinose, fructose, fucitol, fucose, galactose, galacturonate, glucose, glucuronic acid, mannose,  N -acetylglucosamine, rhamnose, or xylose. Uridine diphosphate glycosyl transferases can catalyze formation of either an alpha or beta glycosidic bond.
Patent WO-2021211243-A1 (WO)
Title: Modular screw system with head locker and derotator
Inventor: BUTLER BRIAN
IPC: A61B17/88
Filed: 2021-03-16
Abstract: A universal surgical instrument includes an elongated member having a first end and a second end, the second end having flexible prongs with a head cavity to hold therebetween a polyaxial head. The universal surgical instrument includes a cuff member at the first end to interface with interchangeable surgical instruments. The universal surgical instrument includes an I-shaped clamp coupled to the elongated member and being configured to unlock and separate the flexible prongs to expand the head cavity for placement of the polyaxial head therein and to lock the head cavity in response to application of a force to slide the I-shaped claim along the elongated member to a locked position. A system of surgical instruments include the universal instrument and interchangeable surgical instruments that can be interchanged in the cuff member of the universal instrument.
Patent WO-2021188863-A1 (WO)
Title: Compositions for ovarian cancer assessment having improved specificity and sensitivity
Inventor: FRITSCHE HERBERT
IPC: G01N33/574
Filed: 2021-03-19
Abstract: The present invention provides compositions and methods having improved specificity and sensitivity for the pre-operative assessment of ovarian tumors ( e.g. , symptomatic and asymptomatic adnexal mass) in a variety of subjects ( e.g. , pre- and post-menopausal women) having a variety of ovarian cancer types ( e.g. , low malignant potential, intermediate malignant potential, high malignant potential).
Patent WO-2021207035-A1 (WO)
Title: Methods and apparatus on transform and coefficient signaling
Inventor: WANG XIANGLIN
IPC: H04N19/70
Filed: 2021-04-02
Abstract: This application is directed to a method implemented by an electronic device for decoding video data. The electronic device receives, via a bitstream, a luma transform skip flag, a plurality of luma transform samples, and a low-frequency non-separable transform (LFNST) index associated with a transform unit. After receiving the LFNST index, the electronic device receives, via the bitstream, a chroma transform skip flag and chroma transform samples associated with the transform unit. In accordance with a determination that the LFNST index is non-zero and that the luma transform skip flag is zero, an inverse LFNST is applied on the luma transform samples to generate decoded luma samples for the transform unit. In some embodiments, the LFNST index is received in accordance with a determination that the luma transform skip flag is zero and that a number of none-zero luma samples in the luma transform samples is in a predefined range.
Patent WO-2021217098-A1 (WO)
Inventor: TING ANTHONY E
IPC: C12N5/074
Filed: 2021-04-23
Abstract: The invention is directed to a method of treating viral-induced acute respiratory distress syndrome (ARDS) by administering to a subject with the virial induced ARDS multipotent adult progenitor cells (MAPCs), which are non-embryonic stem, non-germ cells that have a broad differentiation potential and extended replication capacity. The virus inducing the ARDS can be a  Betacoronavirus , such as, severe acute respiratory syndrome (SARS), Corona Virus or Middle East Respiratory Syndrome (MERS), or severe acute respiratory syndrome Corona Virus 2 (SARS-CoV- 2).
Patent WO-2021222434-A1 (WO)
Inventor: ABBOTT CHARLES WILBUR
IPC: C12N15/09
Filed: 2021-04-28
Abstract: Methods for generating a composite biomarker that identifies a predicted level of responsiveness of a subject to a particular type of an immunotherapy treatment is provided. The method can include generating genomic metrics that represent one or more characteristics corresponding to one or more DNA sequences. The method can also include generating transcriptomic metrics represent one or more characteristics corresponding to a set of peptides that are translated from a corresponding RNA sequence of the one or more RNA sequences. The method can also include generating a composite biomarker score derived from the set of genomic metrics and the set of transcriptomic metrics. The method can also include determining, based on the composite biomarker score, a predicted level of responsiveness of the subject to a particular type of an immunotherapy treatment.
Patent WO-2021236798-A1 (WO)
Title: Under-layer for a brake pad of a brake disc rotor
Inventor: SIN XICOLA AGUSTIN
IPC: F16D69/04
Filed: 2021-05-19
Abstract: Technologies are generally described for a composition for an under-layer of a brake pad of a brake disc rotor. The composition may include a fiber pack, a powdered rubber, at least one binder, and at least one filler, wherein the fiber pack includes aramid fibers up to about 3 wt%.
Patent WO-2021257250-A1 (WO)
Title: Authenticated interface element interactions
Inventor: MONTGOMERIE JAMES
IPC: H04W12/08
Filed: 2021-05-24
Abstract: An access control system is provided to prevent the surreptitious granting of access to privacy related functionality on an electronic device. Software-based events to grant access to device functionality can be validated by confirming that the software event corresponds with a hardware input event. This validation prevents the spoofing of a user interface input that may be used to fraudulently grant access to specific functionality.
Patent WO-2021247288-A1 (WO)
Inventor: LI CHIH-PING
IPC: H04W72/04
Filed: 2021-05-25
Abstract: Methods, systems, and devices for wireless communications are described. Generally, the described techniques provide for identification of a slot format for a set of slots where at least one slot format of the set is an subband full-duplex slot (e.g., includes uplink and downlink resources separated in a frequency domain). The base station may transmit one or more semi-persistent scheduling configurations to a UE. The UE may identify semi-persistent scheduling occasions for receiving a downlink communication based at least in part on the SPS configurations matching the format of the slot, the periodicity of the slot formats of the set, or other considerations. The UE and the base station may communicate based at least in part on the determined semi-persistent scheduling occasions.
Patent WO-2021242855-A1 (WO)
Inventor: MEHTA SHALIN
IPC: G02B21/36
Filed: 2021-05-26
Abstract: A method of measuring optical properties of a specimen includes generating illumination light at a plurality of illumination wavelengths and, for each of the plurality of illumination wavelengths, directing the illumination light to impinge on the specimen, collecting sample light passing through the specimen, and detecting the collected sample light using a polarization state analyzer to form a set of polarization channels. The method also includes receiving a calibration tensor, converting the set of polarization channels for each of the illumination wavelengths into Stokes parameter maps using the calibration tensor, denoising the Stokes parameter maps, and deconvolving the Stokes parameter maps to provide density, anisotropy, and orientation measurements of the specimen. The method can multiplex intrinsic density, anisotropy, and orientation measurements of the specimen and density, anisotropy, and orientation measurements of labeled fluorescent molecules.
Patent WO-2021247982-A1 (WO)
Inventor: BARRY OUMAR
IPC: H02G7/05
Filed: 2021-06-04
Abstract: Various embodiments of a system and method for reducing vibrations in and inspecting a suspended cable are described. In one embodiment, a vibration control robot includes a frame roller cage configured to roll open and closed around a cable, a drive system comprising a motor system to maneuver the robot along the cable, and a vibration absorption system to admit and absorb mechanical vibrations from the cable. The vibration absorption system can include a messenger cable segment of a predetermined length, where the messenger cable segment is mechanically coupled with the frame to admit mechanical vibrations on the cable. The vibration absorption system can also include an absorbing counterweight tip mass, a sliding mass, and a permanent magnet of an electromagnetic transducer device, to convert the mechanical vibrations in the messenger cable into electrical energy.
Patent WO-2021257460-A1 (WO)
Title: Disinfection chambers and tunnels
Inventor: FATTOUM FARID
IPC: B27K5/00
Filed: 2021-06-14
Abstract: A disinfection tunnel includes an enclosure, an ozonated water tank, an ozonated water generator, a set of nozzles, a mist generator, and a processor. The ozonated water generator generates ozonated water and stores the ozonated water in the tank. When a person enters the enclosure, the processor starts the mist generator. The mist generator receives ozonated water from the tank, turns the ozonated water to a mist of ozonated water, and pumps the mist of ozonated water to the nozzles. The nozzles spray the mist of ozonated water inside the enclosure for a time period.
Patent WO-2022006192-A1 (WO)
Title: Polycyclic amines for opioid receptor modulation
Inventor: WANG XIAODONG
IPC: A61K31/395
Filed: 2021-06-30
Abstract: The present invention discloses a number of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.
Patent WO-2022011021-A1 (WO)
Title: Use of conserved peptide epitopes from sars-cov-2 for the development of a broad covid-19 vaccine
Inventor: LU YEN-TA
IPC: A61K39/215
Filed: 2021-07-07
Abstract: A vaccine for generation of immunity against SARS-CoV-2 infection includes an S2'-peptide of SARS-CoV-2 in a formulation that enhances immune responses, wherein the S2'-peptide includes the amino acid sequence selected from SEQ ID NO: 1-10. The formulation includes nanocomplexes encapsulating the S2'-peptide, or the formulation includes TREM-like transcript-1 (TREML1) extracellular domain (ECD) or a stalk peptide as an immune booster.
Patent WO-2022011226-A1 (WO)
Title: Parametric modeling and inference of diagnostically relevant histological patterns in digitized tissue images
Inventor: CHENNUBHOTLA SRINIVAS C
IPC: G06K9/62
Filed: 2021-07-09
Abstract: A computational pathology method includes receiving multi-parameter cellular and/or sub-cellular imaging data for an image of a tissue sample, and locating and segmenting a plurality of tissue components of the tissue sample in the multi- parameter cellular and sub-cellular imaging data to generate segmented multi¬ parameter cellular and sub-cellular imaging data. The method further includes applying a parametric feature modelling scheme to certain of the tissue components in the segmented multi-parameter cellular and sub-cellular imaging data, wherein the parametric feature modelling scheme is generated from a dictionary of pre-existing diagnostically relevant histological patterns and comprises a number of structural features adapted for defining a number of disease entities of a disease, and wherein the applying includes determining a quantification of each of the structural features for the tissue sample, and classifying a state of the disease in the tissue sample based the determined quantification of each of the structural features.
Patent WO-2022035794-A1 (WO)
Inventor: HO MITCHELL
IPC: C07K16/30
Filed: 2021-08-10
Abstract: Optimized chimeric antigen receptors (CARs) targeting glypican-1 (GPC1) that include a 12-amino acid hinge region from IgG4 are described. The optimized CARs include a transmembrane domain from either CD8 or CD28. Immune cells, such as T cells or natural killer cells, expressing the optimized CARs can be used to treat GPC1-positive solid tumors.