baber/WOPTO huggingface dataset:
Patent EP-1463801-A2 (EP)
Inventor: ROSENBERG LAWRENCE
IPC: A61K38/10
Filed: 2003-01-10
Abstract: L'induction de la néogenèse de cellules bêta a été associée à l'épithélium canalaire, bien qu'environ 80 % du pancréas soit composé de cellules acineuses. Etonnamment, les cellules acineuses pancréatiques contribuent à la néogenèse des cellules bêta. L'obstruction canalaire partielle (OCP) du pancréas constitue un inducteur connu de la néogenèse des cellules bêta conduisant à l'expansion de la masse des cellules bêta, effet semblant être induit par l'INGAP, une protéine des cellules acineuses identifiée dans la régénération du pancréas de hamster. Nous avons examiné les effets de l'OCP sur l'incorporation de la thymidine tritiée par les cellules acineuses et bêta du pancréas chez les hamsters syriens femelles. Une seule dose de thymidine tritiée a été administrée à tous les animaux deux semaines après l'OCP. Les animaux ont ensuite été sacrifiés 1 heure ou 6 semaine après l'injection. L'incorporation de la thymidine tritiée dans les cellules acineuses était maximale 2 semaines après l'OCP et a décliné 8 semaines après l'OCP. L'incorporation de la thymidine tritiée dans les cellules bêta était inversement proportionnelle à celle observée dans les cellules acineuses. Deux semaines après l'OCP, l'absorption de la thymidine tritiée par les cellules bêta était relativement faible et a augmenté sensiblement 8 semaines après l'OCP, conformément à la néogenèse des cellules bêta trouvant leur origine dans les cellules acineuses. La microscopie électronique a révélé des cellules comportant à la fois des granules proenzymatiques et endocriniens, ce qui suggère encore une transdifférenciation des cellules acineuses en cellules endocriniennes. Dans une deuxième expérience, on a administré aux hamsters un pentadécapeptide de la protéine INGAP ou un volume équivalent de solution saline pendant 10 jours. Le nombre d'amas de cellules bêta associés aux cellules acineuses et aux îlots supplémentaires dans les hamsters traités au peptide INGAP a doublé, ce qui a induit une augmentation de 2,8 de la masse globale des cellules bêta des îlots supplémentaires. La différenciation des cellules acineuses en cellules bêta constitue une autre voie à la néogenèse des cellules bêta ; le peptide INGAp joue un rôle important dans ce processus.
Patent EP-1500279-A2 (EP)
Inventor: CHEN YINGWEI
IPC: H04N7/50
Filed: 2003-04-15
Abstract: A method and system (10) of reducing the computation load of an MPEG decoder by changing the encoding algorithms in a video-processing system are provided. During an encoding mode, a stream of data blocks is received and at least one motion vector and one motion compensation prediction value for each macro-block are generated (12). The prediction value is transformed (14) into a set of DCT coefficients. Prior to the quantizing step, the set of DCT coefficients are modified (14) according to predetermined criteria. To this end, the total energy level of the DCT coefficients excluding the lowest 2x2 DCT coefficients is computed, and last column and last row of the DCT coefficients is discarded alternatively until the total energy level of the DCT coefficients reaches a predetermined energy level. Thereafter, the discarded column or row is assigned to a predetermined value. The modified DCT coefficients are then quantified (16) and encoded (20), thereby generating a bit stream of encoded macro-blocks, which are subsequently decoded according to a conventional decoding process.
Patent EP-1479221-A2 (EP)
Inventor: LOHWEG VOLKER
IPC: H04N1/60
Filed: 2003-02-22
Abstract: The method is applied to a color camera (01) that provides three output signals for three separate output channels corresponding to the acquired colors in the form of output signal vectors (04a). It involves multiplying the output signal vectors, whose coefficients (R,G,B) represent the output signals for the three color channels at a defined position in the observation region (02) with an especially quadratic correction matrix (09).
Patent EP-1480692-A2 (EP)
Inventor: SIMON ADAM
IPC: A61M5/178
Filed: 2003-03-06
Abstract: A treatment device (22) is provided for applying electrical energy to biological tissue in conjunction with injecting a composition. An injector (32) such as a syringe (32) has a reservoir (44) for the treatment composition and injection cannula (34). The cannula (34) can function as an electrode (36), and one or more additional electrodes (36). The electrodes (36) can each have tissue penetrating needles, or one or more of the electrodes (36) can have a surface bearing conductive contact part (136). The syringe (32) or injector (32) and a drive unit (82) that applies electrical power to the electrodes (36) are operable simultaneously or in a sequence. The treatment device (2) uses a disposable syringe (32) received in a carrier (66).
Patent EP-1513943-A2 (EP)
Inventor: VAN NESS JEFFREY
IPC: C12N9/22
Filed: 2003-06-05
Abstract: L'invention concerne des ADN de recombinaison qui codent des endonucléases de coupure, LucNic et MetNic, et la production d'endonucléase de restriction LucNic et MetNic à partir de l'ADN de recombinaison par utilisation de méthylase de modification de LucNic ou de MetNic, respectivement.
Patent EP-1474446-A2 (EP)
Inventor: CARROLL MILES
IPC: C12N15/12
Filed: 2003-02-13
Abstract: There is provided an MHC class II peptide epitope from 5T4 antigen. In particular, there is provided a peptide epitope of 5T4 which comprises one of the following: (i) the minimal epitope from the amino acid sequence shown as SEQ ID No. 2; (ii) the minimal epitope from the amino acid sequence shown as SEQ ID No. 3; (iii) a minimal epitope from the region 281-420 of 5T4. There is also provided a vaccine comprising such a peptide (or precursor thereof) and its use to treat and/or prevent a disease, in particular a cancerous disease.
Patent EP-1499561-A2 (EP)
Inventor: BAGLIONI PIERO
IPC: C01G9/02
Filed: 2003-03-26
Abstract: L'invention concerne une méthode de préparation de particules du Groupe II et d'oxydes et d'hydroxydes de métaux de transition, qui met en oeuvre une étape de synthèse en phase homogène, par réaction de double échange et, dans le cas des oxydes, la calcination subséquente des hydroxydes correspondants. L'invention concerne en outre les particules ainsi obtenues et leur utilisation pour le couchage de surface de matériaux en céramique, en textile ou en papier.
Patent EP-1554109-A2 (EP)
Title: Device for punching, stamping and/or shaping flat elements
Inventor: MARTIN PETER-JOSEF
IPC: B26D5/14
Filed: 2003-10-11
Abstract: A device for punching, stamping and/or shaping flat elements ( 29 ) includes a base body ( 1 ) with a table ( 18 ) and support ( 26 ) for the flat element ( 29 ), and a base plate ( 17 ), which supports a punch ( 24 ), and which is advanced with a drive ( 4,5 ) toward the support ( 26 ) and into a working station (II), bringing the punch ( 24 ) into contact with the support ( 26 ). A large number of successive, very short, highly precise, punching strokes make punched holes or stampings. Short stop periods and short clock times are used for fast moving flat elements ( 29 ). Transfer apparatus ( 9, 7; 35; 43; 46 ) coupled between the drive ( 4,5 ) and the base plate ( 17 ) move the base plate ( 17 ) without building up pressure from a position of rest (I) The punch ( 24 ) is not in contact with the support ( 26 ), up to immediately in front of working position (II). The base plate ( 17 ) is then moved into working position (II) while producing a high pressure between the base plate ( 17 ) and the flat element ( 29 ). During further operation of the drive ( 4,5 ), the base plate ( 17 ) is returned to the position of rest (I,II) without building up pressure.
Patent EP-1559130-A2 (EP)
Inventor: YESHURUN YEHOSHUA
IPC: A61M/
Filed: 2003-10-09
Abstract: La présente invention se rapporte à un procédé de production de microaiguilles. Ce procédé consiste à déposer une première couche d'un polymère sensible au rayonnement sur une surface de travail et à irradier sélectivement ladite première couche de sorte que cette première couche présente au moins une région irradiée et au moins une région non irradiée. Le procédé consiste également à développer la première couche de manière à retirer sélectivement l'une des régions que sont la ou les régions irradiées et la ou les régions non irradiées de sorte que, au moins une partie d'au moins une région restante définisse au moins partiellement une forme d'au moins une partie d'une structure à microaiguilles. Une telle structure à microaiguilles inclut une pluralité de microaiguilles formées au moins partiellement à partir d'un polymère sensible au rayonnement.
Patent EP-1572956-A2 (EP)
Inventor: ROSSI JOHN J
IPC: A61K38/00
Filed: 2003-07-31
Abstract: Amplification-based methods and kits for rapidly producing siRNA expression cassettes are provided. Also provided are methods for expressing amplified siRNA expression cassettes in cells.
Patent EP-1549851-A2 (EP)
Inventor: COUVILLON LUCIEN ALFRED JR
IPC: F04B45/02
Filed: 2003-10-02
Abstract: L'invention concerne une pompe de délivrance de médicaments, qui comprend: (a) une enceinte pouvant se dilater et se contracter à volume interne qui définit un réservoir de médicaments; (b) un ou plusieurs actionneurs polymères électro-actifs; (c) une sortie de médicaments en communication fluidique entre le volume interne et l'extérieur de la pompe; et (d) une unité de contrôle reliée électriquement au(x) actionneur(s) et lui transmettant des signaux électriques. Le ou les actionneurs réduisent le volume interne en fonction de ces signaux. L'invention concerne également un procédé de délivrance d'agent thérapeutique liquide à un patient. Le procédé comprend les étapes suivantes: (a) établissement de la pompe décrite; (b) mise en communication fluidique de la sortie de pompe avec le patient; et (c) transmission des signaux de contrôle au(x) actionneur(s) pour réduire le volume interne, entraînant une partie de l'agent thérapeutique liquide du réservoir par cette sortie à destination du patient.
Patent EP-1545479-A2 (EP)
Inventor: SCHAFFNER CARL P
IPC: A61K31/397
Filed: 2003-07-30
Abstract: A method of prevention or treatment of a cholesterol-associated tumor is provided which comprises administering a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe (SCH 58235) and/or its phenolic glucuronide, or at least one ezetimibe analog, e.g., SCH 48461 and SCH 58053, to a patient wherein the patient is either at risk of developing a cholesterol-associated tumor or already exhibits a cholesterol-associated tumor. Formulations of ezetimibe are also provided for the prevention or treatment of a cholesterol-associated tumor further comprising at least one other anticancer agent. An article of manufacture is also provided which comprises a container, instructions, and a composition, wherein the composition comprises a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe or its phenolic glucuronide, and the instructions are for the administration of the composition for the prevention or treatment of a cholesterol-associated tumor.
Patent EP-1546111-A2 (EP)
Title: Composes derives de la 2-thiohydantoine et leur utilisation pour le traitement du diabete
Inventor: BINET JEAN
IPC: C07D233/86
Filed: 2003-10-03
Abstract: L'invention concerne des composés de la 2-thiohydantoïne choisis parmi les composés de formule générale (I): dans laquelle notamment l'un des radicaux R1 ou R2 comprend dans la structure deux noyaux aromatiques ou représente le groupe dibenzofuranyle, R3 représente un atome d'hydrogène, un atome d'halogène, un groupe alkyle en C1-C4, un groupe alcoxy en C1-C4, un groupe hydroxy, un groupe phényle ou un groupe benzyle, R4 représente un atome d'hydrogène, un atome d'halogène ou un groupe alkyle en C1-C4, et leurs sels d'addition avec un acide non toxique, notamment les sels pharmaceutiquement acceptables. Elle concerne également leur procédé de préparation, les compositions pharmaceutiques les contenant, et leur utilisation en tant que substance pharmacologiquement active, notamment dans le cas du traitement du diabète, des maladies dues à une hyperglycémie, des hypertriglycéridémies, des dyslipidémies ou de l'obésité.
Patent EP-1565897-A2 (EP)
Inventor: OSTERTAG THOMAS
IPC: G08C17/06
Filed: 2003-11-13
Abstract: L'invention concerne le couplage d'un élément de détection à un transpondeur, la liaison entre l'élément de détection et le transpondeur étant réalisée par couplage capacitif ou inductif. Il est possible de conserver une éventuelle couche de séparation entre l'élément de détection et le transpondeur, la présente invention étant particulièrement adaptée à des contenants étanches aux gaz et aux liquides tels que des pneus. En outre, des matériaux électriquement non conducteurs de l'objet à mesurer peuvent servir de diélectrique pour le couplage capacitif et des matériaux électriquement conducteurs peuvent faire partie d'une boucle conductrice pour le couplage inductif.
Patent EP-1558580-A2 (EP)
Inventor: WARSHAKOON NAMAL CHITHRANGA
IPC: C07D213/89
Filed: 2003-11-07
Abstract: La présente invention concerne des composés de formule (I) efficaces pour traiter une infection microbienne.
Patent EP-1479458-A2 (EP)
Inventor: HAUGER ANDREAS DR-ING
IPC: B21C37/08
Filed: 2004-05-24
Abstract: The tube and stock producing process involves producing a tube (11) or stock with varying wall thickness along the length. Endless strip material is flexibly rolled with variably reduced final thickness in the longitudinal direction of the strip. The strip material is deformed into an endless tube or stock article. This is then cut into sections (12, 13, 14, 16).
Patent EP-1492276-A2 (EP)
Inventor: KAWAMURA YUZURU
IPC: H04L12/24
Filed: 2004-06-17
Abstract: A method for accessing an access point (AP) in a wireless LAN and a station are provided that allow users to determine the current country mode and more conveniently and faster perform access to the AP when access to the AP occurs through worldwide roaming. The method extracts country information from a beacon which is received from the access point when access to the access point occurs and displays the country name of the extracted country and a map including the country on a display device. The method manages multiple profiles by grouping into multiple profile groups for each country and tries to access sequentially and automatically all access points which are set in the multiple profiles included in the profile groups of the country. Therefore, if a response from the AP is received, users can receive various services by communication through the AP.
Patent EP-1503276-A2 (EP)
Inventor: NELSON KEITH B
IPC: G06F11/07
Filed: 2004-07-30
Abstract: An "Alert" tab or button (22) is displayed on the Graphical User Interface (GUI)
of a videoconference terminal when a problem is detected in the embedded system.
Selecting the tab or button (22) - e.g., with a pointing device - causes the display to
switch to a diagnostic page which provides a specific indication of the problem which has
occurred. In some embodiments, the diagnostic page may provide a graphical indication
of the status of various sub-systems.
Patent EP-1511075-A2 (EP)
Inventor: OSANAI HIDEYO
IPC: H05K1/03
Filed: 2004-08-26
Abstract: In a method for producing an electronic part
mounting substrate wherein a heat sinking metal base
plate 12 is bonded to one side of a ceramic substrate
10, and one side of a circuit forming metal plate 14
is bonded to the other side thereof, an electronic part
16 being mounted on the other side of the circuit forming
metal plate 14, the ceramic substrate 10 and the
electronic part 16 are arranged in a mold so that the
ceramic substrate 10 is spaced from the electronic part
16, and then, a molten metal is injected into the mold
so that the molten metal contacts both sides of the
ceramic substrate 10 and the electronic part 16. Then,
the mold is cooled to solidify the molten metal, to
form a heat sinking metal base plate on one side of
the ceramic substrate 10 so that the heat sinking metal
base plate is bonded directly to the one side of the
ceramic substrate 10, and to form a circuit forming
metal plate on the other side of the ceramic substrate
10 so that one side of the circuit forming metal plate
is bonded directly to the other side of the ceramic
substrate 10. When the circuit forming metal plate is
formed, the electronic part is bonded directly to the
other side of the circuit forming metal plate.
Patent EP-1518728-A2 (EP)
Inventor: OGAWA SATOSHI
IPC: G05G1/00
Filed: 2004-09-22
Abstract: A plurality of click portions (22) is formed integrally with
a unit body (17). The click portions are arranged on a common circular
track, and a dial (24) is engaged with the click portions so as to
be unstable and to be prevented from slipping off. Therefore,
it is not necessary to provide a D spring for coupling the dial
to a shaft so as to be unstable and to be prevented from slipping
off. Consequently, it is possible to reduce the number of
components and a cost.
Patent EP-1548366-A2 (EP)
Inventor: POERNER HARALD
IPC: A47L15/42
Filed: 2004-11-05
Abstract: The door hinge (2) for the door of a domestic appliance has two sections (3,4) which are pivotable in relation to one another within a pivot angle range between a minimum and a maximum angle. The hinge has an additional functional unit (5) which is connected to both hinge sections and which can occupy at least two functioning positions. At least one predetermined functioning position of the functional component is clearly associated with a predetermined pivoting angle between the hinge sections. An independent claim is included for a domestic appliance, and especially an oven, freezer, refrigerator, dish washer or washing machine, which has a door equipped with the aforesaid hinge.
Patent EP-1548587-A2 (EP)
Inventor: CROSS BRIAN
IPC: G06F9/445
Filed: 2004-12-14
Abstract: Described is a system and method in which software images
including updates are provided as packages. The package is
self-describing, thereby facilitating the replacement of only
component parts of an image. A software build process maps
operating system features (comprising files, metadata,
configuration information and so forth) into the packages, and
executable code is processed for relocation purposes. The final
package includes a device manifest file that describes the
package and conveys dependency information and information about
the priority of settings (shadow data).
Patent EP-1566703-A2 (EP)
Inventor: MORIBE SHUHEI
IPC: G03G9/08
Filed: 2004-12-22
Abstract: A toner is disclosed including toner particles
containing a binder resin and a colorant. The binder
resin contains a vinyl resin. In the high-temperature
GPC-RALLS-viscometer analysis of the o-dichlorobenzene-soluble
matter of the toner, a
weight-average molecular weigh of absolute molecular
weights measured with a viscosity detector is in a
specific range. In the o-dichlorobenzene-soluble
matter, a component with the absolute molecular weight
of 10,000 or less and a component with the absolute
molecular weight of 1,000,000 or more are present in
specific proportions, respectively. The intrinsic
viscosity of the toner is in a specific range.
Patent EP-1468932-A2 (EP)
Inventor: DE CAMBRY DE BAUDIMONT GUY
IPC: B65D41/00
Filed: 2002-11-06
Abstract: A screw cap is disclosed comprising a composition based on a multimodal
ethylene polymer having a standard density (SD) greater than 950 kg/m 3  and a melt
flow index MI 2  of less than 2 g/10min, said multimodal ethylene polymer comprising-from
35 to 65wt%, based on the total weight of the multimodal ethylene polymer, of a
fraction of ethylene polymer (A) having an SD(A) of more than 965 kg/m 3  and a melt
flow index MI 2 (A) of at least 10 g/10min but less than 400 g/10min, and 
from 65 to 35wt%, based on the total weight of the multimodal ethylene polymer, of a
fraction of a copolymer (B) of ethylene and at least one alpha-olefin containing from 3
to 12 carbon atoms, and having a melt flow index MI 2 (B) of less than 10 g/10min and a
content of said alpha-olefin(s) of from 0.1 to 5 mol%.
Patent EP-1465009-A2 (EP)
Title: Photo reticles using channel assist features
Inventor: ZHIJIAN LU
IPC: G03F1/00
Filed: 2004-03-31
Abstract: Photo reticles (110) are formed comprising a first and
second printable features (130), (140) which are connected by a
channel assist feature (150). The size of the channel assist
feature is such that the channel assist feature will not
substantially print on photoresist that is exposed using the
reticle. Third printable features (120) can be placed at
distances W D  from the channel assist feature (150). The channel
assist feature will assist in the formation of the third
printable feature (120).
Patent EP-1491715-A2 (EP)
Inventor: ROBERTS JOHN
IPC: E21B31/00
Filed: 2004-06-18
Abstract: A back-off tool for use in a tubular member disposed inside a wellbore. The back-off tool includes a housing and at least one sonic wave generator mounted within the housing. The sonic wave generator is configured to generate a plurality of sonic waves.
Patent EP-1475708-A2 (EP)
Inventor: FUJIKI MASAKAZU
IPC: G06F15/16
Filed: 2004-05-07
Abstract: Provided is a technique for limiting
association of a process to a system where a
plurality of processes share data. It is determined
whether or not a device itself satisfies a specific
condition, and, depending on a result thereof, an
instruction to set or release the specific condition
is issued to all client devices sharing the data.
Further, when the instruction is received, if the
received instruction is the instruction to set or
release the specific condition, it is then determined
whether or not the specific condition is breached.
If the device itself breaches the specific condition,
then a communication path to a server device is
disconnected. If the device itself is not breaching
the specific condition, then information relating to
the device satisfying the specific condition is
updated in accordance with the instruction.
Patent EP-1517514-A2 (EP)
Inventor: MATSUSHIMA HIROYUKI
IPC: H04L29/06
Filed: 2004-09-22
Abstract: A communication apparatus, a communication
system, a communication apparatus control method and a
recording medium for storing an implementation program
thereof are disclosed. The communication apparatus
includes a communication part providing a communicating
party with an individual certificate with identification
information thereof as via a first address and a common
certificate without the identification information via a
second address; a request execution part executing a
process corresponding to a request received from the
communicating party; and a denial part denying any
process corresponding to requests other than a request
to set the individual certificate in communication via
the second address. According to the invention, it is
possible to easily maintain a condition where
authentication can be properly performed while
maintaining security of communication.
Patent EP-1467188-A2 (EP)
Inventor: COGNOT GILLES
IPC: G01F3/08
Filed: 2004-04-02
Abstract: The meter, comprising housing (2) with base (2B) with connecting pipes (3,4) and measuring chamber (1) with aperture (5) sealed to connecting pipe, has seal (6) designed to be compressed between surface of chamber and inner surface of housing and made in the form of a bead of a polymerizable plastic applied to surface. The seal is applied, for example, in a groove between two ribs (9A, 9B) on the measuring chamber surface before the chamber is fitted into the base and is polymerized after fitting. In a variant of the process, the seal can be injected between the surfaces after fitting the measuring chamber.
Patent EP-1510226-A2 (EP)
Inventor: VESCHI RAFFAELE
IPC: A61L2/03
Filed: 2004-05-21
Abstract: Process for sterilizing the surfaces of objects by removing bacterial films comprises subjecting the surface to an electrical and/or magnetic field to destroy the bacteria. An independent claim is also included for a device used for carrying out the above process. Preferred Features: The surface is subjected to an electrical and/or magnetic field that varies with time.