baber/WOPTO huggingface dataset:
Patent CA-2195856-C (CA)
Inventor: MOSCHEL ROBERT C
IPC: A61K31/53
Filed: 1995-07-31
Granted: 2008-09-30
Abstract: The present invention provides AGT inactivating compounds such as substituted O6-benzylguanines of formula (I) wherein 7- or 9-substituted 8-aza-O6-benzylguanines, 7,8-disubstituted O6-benzylguanines, 7,9-disubstituted O6-benzylguanines, 4(6)-substituted 2-amino-5-nitro-6(4)-benzyloxypyrimidines, and 4(6)--substituted 2-amino-5-nitroso-6(4)-benzyloxypyrimidines, as well as pharmaceutical compositions comprising such compounds along with a pharmaceutically acceptable carrier. The present invention further provides a method of enhancing the chemotherapeutic treatment of tumor cells in a mammal with an antineoplastic alkylating agent which causes cytotoxic lesion at the O6-position of guanine, by administering to a mammal an effective amount of one of the aforesaid compounds, 2,4-diamino-6-benzyloxy-s-triazine, 5-substituted 2,4-diamino-6-benzyloxypyrimidines, or 8-aza-O6-benzylguanine, and administering to the mammal an effective amount of an antineoplastic alkylating agent which causes cytotoxic lesions of the O6-position of guanine.
Patent CA-2198480-C (CA)
Inventor: PODOSEK EDWARD
IPC: B42F13/00
Filed: 1995-08-24
Granted: 2001-01-16
Abstract: L'invention concerne un classeur à anneaux facile à saisir par le dos. Ce classeur à anneaux (101) comprend un ensemble de renforcement (113) présentant des panneaux de renforcement avant (115) et arrière (117) reliés par un support flexible (119). Cet ensemble de renforcement (113) est dépourvu de tout renforcement disposé entre les panneaux de renforcement avant et arrière (115, 117). Un matériau de toile est fixé sur la surface intérieure (121) et extérieure (123) de l'ensemble de renforcement (113). Un ensemble à anneaux (141) est fixé au panneau arrière de renforcement de couverture (117). Ainsi, les feuilles de surface (121, 123) et l'ensemble de renforcement (113) coopèrent pour former une couverture de classeur (131) présentant une couverture avant et arrière (133, 135) reliée par un dos flexible (137) épousant la forme de l'ensemble à anneaux (141).
Patent CA-2199688-C (CA)
Inventor: GRUNZE MARK R
IPC: B25B27/06
Filed: 1997-03-11
Granted: 2005-08-02
Abstract: Disclosed herein is a tool for swaging a bearing into an opening in a bearing housing, which apparatus is operable in confined spaces, such as in an aircraft application. The tool has a threaded elongated member or bolt that extends through the bore of the bearing.      The tool also has a roller fixture assembly adapted to be positioned on one side of the bearing and positioned on one end of the elongated member. The roller fixture assembly has a number of rollers and a roller fixture shell that supports the rollers for engagement with the bearing to swage the bearing against the bearing housing. The bearing swaging tool also has a locating fixture assembly adapted to be positioned on the opposite side of the bearing from the roller fixture assembly. The locating fixture assembly is supported on the other end of the elongated member and includes a locating fixture with a first side adapted to be positioned against the bearing and bearing housing.      The locating fixture assembly includes means for selectively controlling the amount of axial movement of the locating fixture with respect to the elongated member in response to rotation of the elongated member with respect to the bearing.
Patent CA-2201442-C (CA)
Title: Desiccant composition
Inventor: SHELLEY RICHARD M
IPC: B65D65/40
Filed: 1997-04-01
Granted: 2002-05-21
Abstract: Disclosed is a new desiccant composition comprised of calcium chloride and starch.  Preferably the starch is a modified starch, preferably a modified corn starch.  The composition contains from about 5 to about 95 percent calcium chloride and from about 5 to about 95 percent starch.
Patent CA-2203245-C (CA)
Title: Rotatable sewing cuff for a heart valve prosthesis
Inventor: GRAF JAMES E
IPC: A61F2/24
Filed: 1995-10-20
Granted: 2003-09-02
Abstract: The invention provides a sewing cuff assembly (32) for mounting to the body (22) of a heart valve prosthesis (20). The sewing cuff assembly comprises a resiliently deformed spring (42) for exerting a force directed toward the orifice structure. When a torque is applied to the valve (20), the force results in a rotation-resisting torque sufficient to resist rotation during normal operation of the valve (20) after implantation but low enough to permit assisted rotation, as during surgery.
Patent CA-2205894-C (CA)
Title: Production of a siliceous refractory mass
Inventor: MEYNCKENS JEAN-PIERRE
IPC: C04B35/65
Filed: 1995-11-23
Granted: 2004-04-20
Abstract: A process is provided producing a crystalline siliceous refractory mass by projecting solid refractory particles, solid silicon particles and gaseous oxygen against a surface in such a way that reaction between the silicon particles and gaseous oxygen occurs against the surface, thereby releasing the heat of reaction against the surface so that a coherent refractory mass comprising cristobalite is formed, wherein the solid refractory particles comprise silica in the form of vitreous silica and in that the surface against which they are projected is at a temperature of a least 1000 °C. The process can be used for in situ repair of high temperature furnaces such as glassmaking furnaces or for the manufacture of high quality refractory bricks.
Patent CA-2210568-C (CA)
Title: Method and apparatus for stripper bar rotation
Inventor: POPLAWSKI LEON G
IPC: G03G15/00
Filed: 1997-07-16
Granted: 2001-04-24
Abstract: Disclosed is a novel method and apparatus for rotating a stripper bar associated with a paper path.  A cam and cable mechanism replaces a rigid link mechanism on the stripper bar, the cam and cable mechanism providing for a much greater angle of rotation of the stripper bar than the rigid link mechanism.  The additional rotation allows the stripper fingers on the stripper bar to the rotated completely out of the way of a paper jam clearance path.  Other new developments include a wrench positioning system that controls the orientation of the stripper bar and an over-rotation prevention system that stops the rotation of the stripper bar when the stripper bar and stripper fingers are being serviced.
Patent CA-2215291-C (CA)
Inventor: SEELIG ANTON
IPC: H02J5/00
Filed: 1995-12-21
Granted: 2000-04-04
Abstract: A device for the contactless inductive transmission of electric energy to a movable consumer has a stationary primary circuit designed as an arrangement of elongated parallel leads connected to a source of high frequency alternating voltage or current and a transmission head arranged on the movable consumer. The transmission head consists of a ferrite core and of a secondary winding that surrounds the ferrite core and is magnetically coupled to the primary circuit. The primary circuit lead arrangement has an outer lead designed as an almost closed housing (7) and a middle lead (6) arranged approximately at the center of the housing. The current (II) that flows in the outer lead has the same intensity but an opposite flow direction to the current in the middle lead. The middle lead (6) is surrounded by a U-shaped ferrite core (2) that carries the secondary winding (W2). In order to transmit electric energy independently and at the same time to several movable consumers, a constant medium frequency current (J1) flows through the transmission device. The current is kept constant in that the transmission arrangement is connected in parallel to a capacitor (CE) connected in series to an inductor (LE) and to a medium frequency voltage source (MFG1). A resonance is created between the inductor (LE) and the capacitor (CE) at the frequency (fo) of the medium frequency voltage source (MFG1).
Patent CA-2218507-C (CA)
Inventor: FRICANO NICHOLAS J
IPC: A47B63/00
Filed: 1997-10-16
Granted: 2007-06-26
Abstract: An overhead storage cabinet having a housing defined by top and bottom wall rigidly joined by end walls to define an interior storage compartment therein. A door assembly is vertically swingably mounted on the housing and includes a door panel which vertically closes a front access opening of the housing when in an open position, and which swings upwardly into an open position wherein the door panel is stored generally above the top wall. The door assembly includes end panels which exteriorly overlap and are hingedly coupled to the end walls. The end panels mount one or more counterweight elements adjacent the ends thereof to counterbalance the door panel weight. The number or position of counterweight elements is selected in accordance with the longitudinal length of the door panel.
Patent CA-2219424-C (CA)
Inventor: REINICHE SCOTT L
IPC: F04C29/02
Filed: 1997-10-24
Granted: 2000-08-01
Abstract: A compressor having an oil pick-up tube which filter incoming lubricant, and increases the volumetric pumping capacity of the compressor. The oil pick-up tube is attached to the crankshaft of the compressor, and is partially disposed within an oil sump also provided in the compressor. When the motor of the compressor is energized, the crankshaft and the oil pick-up tube rotate, and oil from the oil sump is drawn into the oil pick-up tube. A passageway is provided within the motor shaft to communicate oil from the oil pick-up tube to the compressor mechanism of the compressor for lubrication purposes. A cylindrical screen is also provided within the oil pick-up tube to both filter the incoming oil and provide a surface to which the oil adheres as it migrates upward through the rotating tube and expels the oil radially outwardly to increase the velocity of the migrating oil. The volumetric pumping capacity of the compressor is thereby increased. A pitot tube is provided at the top of the axial oil passageway to create an additional vacuum within the axial oil passageway and thus increase the volumetric pumping capacity of the compressor.
Patent CA-2223415-C (CA)
Title: Automated biopsy instruments
Inventor: KUPEC THOMAS
IPC: A61B10/00
Filed: 1996-05-23
Granted: 2003-07-29
Abstract: The present invention provides automated biopsy instruments (10) especially useful for improving minimally invasive medical procedures to obtain soft tissue biopsy samples. The biopsy instruments (10) provide side-by-side actuators (30, 32) which retract a stylet (22) and a cannula (20) in specific sequences. The biopsy instruments (10) may include a single spring or two springs (48) to sequentially fire the stylet (22) and the cannula (20).
Patent CA-2228239-C (CA)
Inventor: KYYTSONEN MARKKU
IPC: B65H18/26
Filed: 1991-10-25
Granted: 2002-07-09
Abstract: A web is reeled onto successive reeling drums to form respective jumbo rolls by reeling the web onto a first reeling drum at a reeling position to form a first jumbo roll, the first reeling drum being driven by a center drive. When the first jumbo roll is full, a second reeling drum is delivered to a standby position and is accelerated to web speed.  A transfer device is employed to transfer the first jumbo roll to an exchange position while the center drive remains connected thereto.  The second reeling drum is transferred to the reeling position and the web is exchanged from the first jumbo roll to the second reeling drum.  The first jumbo roll is decelerated and the transfer device is shifted from the first jumbo roll to the second reeling drum.  The center drive is connected to the second reeling drum.
Patent CA-2229615-C (CA)
Title: Improved mobile earth terminal
Inventor: WARD MICHAEL K
IPC: H04B7/185
Filed: 1996-08-05
Granted: 2002-10-29
Abstract: In a mobile satellite system, a mobile communication system includes a user interface system, an antenna system, a transceiver system, a logic and signaling system. The logic and signaling system provides a roam function permitting the mobile communication system to roam between the mobile satellite system and a terrestrial based communication system responsive to the user selection of a primary service and an alternate service. The mobile  communication system also includes a digital terminal equipment unit initiating setup and release for a data call, and a facsimile interface unit  initiating setup and release for a facsimile call. The facsimile interface unit generates a line control packet responsive to a line state transition indicating transmission of information associated with a new line state over  a communication channel. The facsimile interface unit includes a look ahead buffer to perform early line control packet detection by looking ahead a predetermined time interval into a received satellite data stream and identifying a valid idle line control packet.
Patent CA-2230242-C (CA)
Inventor: PERSSON AGNE CLAES
IPC: A22C25/08
Filed: 1996-08-21
Granted: 2007-12-04
Abstract: An apparatus and a method for transferring an irregular stream of objects fr om a first conveyor (10) to a second conveyor (12) in such a way that the objects form a regular stream of objects on the second conveyor (12). The first conveyor (10) operates with a higher conveying speed than the second conveyor (12) and for some distance in parallel with the second conveyor. A deflection means (15; 18; 32) for movable deflection of objects (14) between the two conveyors (10, 12 ) is provided with means (21-25; 34) for synchronization with the movement of the second conveyor (12). The objects (14) being convey ed upon the first conveyor (10) are deflected from this conveyor over to the second conveyor (12) at various points along the above mentioned distance, depending upon how closely the objects are transported upon the first conveyor (10).
Patent CA-2232744-C (CA)
Inventor: LOPATA FRANCES G
IPC: C06C7/00
Filed: 1996-09-26
Granted: 2000-12-26
Abstract: A lead-free primer mix based on diazodinitrophenol, tetrazene, nitrocellulose, barium nitrate and at least one of PETN, aluminum and antimony sulfide exhibits performance characteristics comparable to lead styphnate compositions.
Patent CA-2236961-C (CA)
Inventor: HULSE DANIEL V
IPC: A61B7/04
Filed: 1996-10-22
Granted: 2004-09-28
Abstract: An electronic stethoscope emulates the frequency response of a standard acoustical stethoscope in both bell and diaphragm modes, while providing additional features attainable only with an electronic stethoscope, such as signal amplification, noise reduction, wider bandwith, and mode selection. The electronic stethoscope includes spectrally separate idealized diaphragm and idealized bell modes. The idealized diaphragm mode and the idealized bell mode each include emphasized passbands and de-emphasized passbands. The emphasized passbands are spectrally separate. In addition, the electronic stethoscope also includes a wideband mode, which permits the user to hear high frequency sounds such as those associated with mechanical heart valves, lung sounds, and the like.
Patent CA-2239195-C (CA)
Inventor: LANG KO C
IPC: A01K67/027
Filed: 1996-12-23
Granted: 2002-12-10
Abstract: A ceramic packing clement (500) is formed from a stack of ceramic plates (502) having parallel ribs (504) forming parallel grooves therebetween. The grooves are formed into channels by being contacted with the surface of an opposed plate. The ribs (504) may engage the end surfaces of ribs on an adjacent plate or may be interleaved with the ribs (504) of an opposed plate to form smaller channels. The plates (502) are adhered to each other by firing a stack of plates (502) in the green state or by adhering cured plates (502) by means of an inorganic adhesive such as sodium silicate. Pressure drop and cracking may be reduced, mass transfer and heat efficiencies increased by enlarging the inlets (542) to the channels and by providing perforations through the plates between the ribs (504). Elements may be preassembled into larger units before placement in a column by wrapping metal bands around an assembly of elements.
Patent CA-2245006-C (CA)
Inventor: SGARLATO GREGORY D
IPC: C12N9/64
Filed: 1997-01-31
Granted: 2002-12-31
Abstract: The present invention relates to improved recombinant vectors which allow for the production of fusion proteins. The present invention also relates to methods for the expression and purification of authentic recombinant proteins from such fusion proteins. In particular, the present invention relates to fusion proteins wherein additional domains and/or elements are added to the fusion proteins. Included in these domains and/or elements are Fc fragments (1) fused to proteins of interest (2) by a polypeptide comprising a hinge region (3), hydrophilic spacer (4), and a dibasic amino acid endoprotease cleavage site (5), wherein the spacer may be cleaved and then digested by carboxypeptidase B (6) to yield the authentic protein (2).
Patent CA-2247066-C (CA)
Inventor: YEN WEI
IPC: H04M11/00
Filed: 1997-12-17
Granted: 2011-09-20
Abstract: The invention provides a method and system for receiving incoming information from multiple information sources, both interactive and passive, and for engagingly presenting that information to a recipient on a presentation interface. The system includes a "background" element, which interacts with interactive information sources and receives from passive information sources, and determines whether information from those sources is likely to be interesting to the recipient, possibly using one information source to determine priority for another. The system also includes a "foreground" element, which presents information to the recipient when active, but not when inactive. The background is operative even when the foreground element is inactive, and when the background detects new information of interest to the recipient (for example, exceeding a selected threshold of interest or satisfying a selected criterion for interest), it causes the foreground to become active and engage the recipient to select and view that new information. The threshold or criterion may be adaptively responsive to recipient preferences,  whether explicitly expressed or implied, but may also be relatively fixed, such as a scheduled time of day.
Patent CA-2248163-C (CA)
Inventor: CROSS JOHN ROBERT
IPC: B60J3/02
Filed: 1997-03-05
Granted: 2006-08-22
Abstract: A visor (10) comprises a main movable first visor part comprising back plate (12) and front plate (14) and an auxiliary sheet-like second visor part (16) therebetween. The sheet-like second visor part is carried on the first visor part (12, 14) by, for example, arms (30) to allow movement in the plane of the sheet. The arms (30) guide the auxilia ry visor part (16) during movement downwards and sideways from a stowed position on the first visor part (12, 14). Alternatively, the auxiliary visor part may be guided by a V-shaped slot (54) or circular groove arrangement (140).
Patent CA-2249958-C (CA)
Inventor: TOGNI ANTONIO
IPC: C07F15/00
Filed: 1998-10-13
Granted: 2008-12-09
Abstract: The invention relates to binuclear iridium(I) phosphine complexes of the general formula   in which X is fluorine, chlorine, bromine or iodine, and   ~is in each case a chiral bidentate diphosphine ligand. The complexes are particularly suitable as catalysts for the inter- or intramolecular asymmetric hydroamination of prochiral olefins.
Patent CA-2253673-C (CA)
Title: 21-substituted progesterone derivatives as new antiprogestational agents
Inventor: KIM HYUN K
IPC: A61K31/57
Filed: 1997-04-30
Granted: 2009-09-08
Abstract: A compound having general formula (I) in which R1 is a member selected from the group consisting of -OCH3, -SCH3, -N(CH3)2, -NHCH3, -CHO, -COCH3 and -CHOHCH3; R2 is a mem-ber selected from the group consisting of halogen, alkyl, acyl, hydroxy, alkoxy, acyloxy, alkyl car-bonate, cypionyloxy, S-alkyl and S-acyl; R3 is a member selected from the group consisting of alkyl, hydroxy, alkoxy and acyloxy; R4 is a member se-lected from the group consisting of hydrogen and alkyl; and X is a member selected from the group consisting of -O and -N-OR5, wherein R5 is a member selected from the group consisting of hydrogen and alkyl. In addition to providing the compounds of formula (I), the present invention provides methods wherein the compounds of formula (I) are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce labor; and for contraception.
Patent CA-2267423-C (CA)
Inventor: GORRELL BRIAN
IPC: G01N27/04
Filed: 1999-03-30
Granted: 2003-05-27
Abstract: An instrument for measuring the resistance of liquid paints and the surface resistance of articles to be coated electrostatically, includes a voltage multiplier circuit that multiplies a periodic. low voltage signal to generate a resistance measuring voltage applied to first and second electrodes for resistance measurements. The electrodes are coupled to differential inputs of an A/D converter having an oscillator output for supplying the periodic low voltage signal to the multiplier circuit. Resistance, voltage and current measuring circuits are alternately switchable between the electrodes and the differential inputs of the A/D converter for measuring resistance, voltage and current, the results of which are displayed visually.
Patent CA-2267561-C (CA)
Inventor: LEVANON NADAV
IPC: H04W84/06
Filed: 1997-09-26
Granted: 2004-10-19
Abstract: A system and method for determining the position of a user terminal (for example, a mobile wireless telephone) in a low-Earth orbit satellite communications system (100). The system includes a user terminal (106), at least one satellite (104) with a known position and velocity, and a gateway (102) (that is, a terrestrial base station) for communicating with the user terminal (106) through the satellite (104). The method includes the steps of determining a range parameter (802) and a range-rate parameter (806). A range parameter represents a distance between the satellite and the user terminal. A range-rate parameter represents a relative radial velocity between that satellite and the user terminal. The position of the user terminal on the Earth's surface is then determined (810) based on the range parameter, the range-rate parameter, and the known position and velocity of the satellite.
Patent CA-2270692-C (CA)
Inventor: ICHIHA HIDEKI
IPC: A41C3/12
Filed: 1999-05-04
Granted: 2005-06-21
Abstract: Women's clothing has a slidable adjuster A provided between the left and right breast cup portions 1, 1'. The adjuster A comprises an outer casing 10 and a pair of sliding members 20. The wearer can change the positions of engagement between first engaging portions 12 provided in the outer casing 10 and at least one second engaging portion 20 provided in the sliding members 20 by operating the pair of sliding members 20, so that the distance between the breast cup portions 1, 1' can be adjusted to a desired level either when the clothing is being put on or after the clothing is put on.