baber/WOPTO huggingface dataset:
Patent CA-2936615-A1 (CA)
Inventor: LEMKE EDWARD
IPC: C07C271/34
Filed: 2015-01-14
Abstract: The present invention relates to methods for linking tetrazines with dienophiles to establish at least two linkages by sequentially performing at least two cycloaddition reactions. The methods in particular allow establishing multi-labeling strategies. In particular, the invention relates to methods for forming linkages by cycloaddition reactions, wherein the method comprises reacting a first alkyl-substituted tetrazine with a first dienophile comprising a irans-cyclooctenyl group followed by reacting a second tetrazine with a second dienophile comprising a cyclooctynyl group, wherein the reaction of the first tetrazine with the first dienophile proceeds in the presence of the second dienophile.
Patent CA-2937056-A1 (CA)
Title: Decoding a combined amplitude modulated and frequency modulated signal
Inventor: JENSEN JESPER BEVENSEE
IPC: H04B10/61
Filed: 2015-02-06
Abstract: The present disclosure relates to a method for decoding a combined AM/FM encoded signal, comprising the steps of: combining said encoded optical signal with light from a local oscillator configured with a local oscillator frequency; converting the combined local oscillator and encoded optical signal into one or more electrical signals by means of at least one opto-electrical converter having a predefined frequency bandwidth, thereby providing an amplified and encoded electrical signal having one or more encoded signal current(s), where one type of states have a higher oscillation frequency than other type of states; rectifying the encoded signal current(s), thereby obtaining an encoded power spectrum, wherein said power spectrum has different states, such as "0"-states and "1"-states, with different power levels such that they can be discriminated, said local oscillator frequency is defined by a positive local oscillator frequency-offset from the frequency of one of the states in said encoded optical signal, and said local oscillator frequency-offset is selected to be dependent on said frequency bandwidth.
Patent CA-2939073-A1 (CA)
Title: Pcr device provided with unidirectional sliding means and pcr method using same
Inventor: KIM SUNG WOO
IPC: C12Q1/68
Filed: 2015-02-09
Abstract: One embodiment of the present invention relates to a PCR device provided with a unidirectional sliding means and a PCR method using same. According to the present invention, the amount of samples treated can be increased by simultaneously, rapidly, and accurately performing a PCR on a large number of samples through sequential thermal contact between a thermal block in which at least two heaters are repeatedly arranged and a PCR chip in which at least two reaction chambers are repeatedly arranged. Also, the present invention is capable of: significantly improving PCR yield by preventing radial heat distribution generated by each heater and consequent non-uniform thermal overlap between adjacent heaters; significantly contributing to size reduction and integration of the device by not requiring a separate temperature control means; simultaneously and rapidly amplifying multiple nucleic acid samples by using the thermal block in which heater units are repeatedly arranged and a plate-shaped PCR reacting portion; and confirming a nucleic acid amplifying step in real time by measuring continuous optical signals or electrochemical signals.
Patent CA-2941167-A1 (CA)
Title: Autonomous firefighting tower
Inventor: THOMSEN GARRY DALE
IPC: A62C27/00
Filed: 2016-09-07
Abstract: An autonomous firefighting tower is a structure that is deployed into a firefighting zone for extinguishing a fire as well as for protecting firefighting personnel on the ground. The structure is able to self-level when being deployed on uneven terrain and requires minimal setup aside from connection to an external water source. A plurality of tower supports is hingedly connected to a base platform and may be adjusted to the terrain. Additional adjustability is provided through a plurality of self- leveling legs. A plurality of stabilizing members provides structural support and stability to the structure during self-leveling and when deployed. A fluid dispenser is connected to the base platform. Water is provided to the fluid dispenser from an external source through a fluid conduit. A control unit and at least one camera allow a remote operator to operate the structure during a firefighting operation.
Patent CA-2944942-A1 (CA)
Inventor: LEFORT GUILLAUME
IPC: F16C25/06
Filed: 2016-10-07
Abstract: Un pied d'une pale s'étend selon une direction longitudinale (B) entre une extrémité proximale et une extrémité distale. Le roulement autorise une oscillation du pied autour d'un axe (B) s'étendant selon la direction longitudinale par rapport à un boîtier. Le roulement comprend une bague extérieure (13) unique, une première bague intérieure (11) présentant un siège distal (16), une deuxième bague intérieure (12) emmanchée sur le siège (16) et étant maintenue axialement en butée contre la première bague intérieure (11). La surface intérieure (14) de la première bague intérieure (11) comprend un épaulement (20) d'assemblage à un pied de pale. La surface extérieure (34) de la bague extérieure (13) unique comprend un épaulement (39) d'assemblage à un boîtier.
Patent CA-2945077-A1 (CA)
Title: Nouveaux derives pyrazolo-pyrimidine et leur utilisation comme inhibiteurs de malt1
Inventor: PISSOT SOLDERMANN CAROLE
IPC: A61P37/00
Filed: 2015-05-27
Abstract: La présente invention concerne de nouveaux dérivés pyrazolo-pyrimidine de formule (I) ou un sel pharmaceutiquement acceptable desdits dérivés. Dans la formule (I), R1 représente halogène, cyano ou C1-C3alkyle éventuellement substitué par halogène; R2 représente C1-C6 alkyle éventuellement substitué une ou plusieurs fois par C1-C6alkyle, C2-C6alcényle, hydroxyle N,N-di-C1-C6alkyle amino, N-mono-C1-C6alkyle amino, O-Rg, Rg, phényle, ou par C1-C6alcoxy, cet alcoxy pouvant à son tour être éventuellement substitué par C1-C6alcoxy, N,N-di-C1-C6alkyle amino, Rg ou phényle; C3-C6cycloalkyle éventuellement substitué par C1-C6alkyle, N,N-di-C1-C6alkyle amino ou C1-C6alcoxy-C1-C6alkyle, et/ou deux desdits substituants éventuels, avec l'atome auquel ils sont liés, peuvent former un noyau hétérocyclique saturé à 4 - 6 éléments, annelé ou spirocyclique, comprenant 1 - 2 atomes de O; phényle éventuellement substitué par C1-C6alcoxy; un noyau hétéroaryle à 5 ou 6 éléments ayant 1 à 3 hétéroatomes choisis parmi N et O, ledit noyau pouvant être éventuellement substitué par C1-C6alkyle qui peut être éventuellement substitué par amino ou hydroxy; Rg; ou N,N-di-C1-C6alkyle amino carbonyle; et R représente phényle indépendamment substitué deux fois ou plus par Ra, 2-pyridyle indépendamment substitué une ou plusieurs fois par Rb, 3-pyridyle indépendamment substitué une ou plusieurs fois par Rc, ou 4-pyridyle indépendamment substitué une ou plusieurs fois par Rd; qui interagissent généralement avec l'activité autoprotéolytique et/ou protéolytique de MALT1, et en particulier qui peuvent inhiber ladite activité. La présente invention concerne également la synthèse de ces nouveaux dérivés pyrazolo-pyrimidine, leur utilisation comme médicament, en particulier pour leur interaction avec l'activité autoprotéolytique et/ou protéolytique de MALT1.
Patent CA-2946386-A1 (CA)
Inventor: WALDER HAROLD
IPC: A61N5/10
Filed: 2015-04-22
Abstract: La présente invention concerne un système et un procédé d'imagerie ou de traitement d'une maladie dans un corps humain ou animal. Le système fournit au corps humain ou animal un support pharmaceutique comprenant un ou plusieurs phosphores qui sont capables d'émettre de la lumière ultraviolette ou visible dans le corps et qui servent de contraste radiographique. Le système comprend un ou plusieurs dispositifs qui administrent par perfusion à un site malade un médicament photoactivable et le support pharmaceutique, une source d'énergie d'initiation comprenant une source de rayons x ou une source d'énergie élevée qui expose aux rayons le site malade avec au moins un élément parmi des rayons x, des rayons gamma ou des électrons, pour ainsi initier l'émission de ladite lumière ultraviolette ou visible dans le corps, et un processeur programmé pour au moins un élément parmi 1) la production d'images du site malade et 2) la commande d'une dose desdits rayons x, rayons gamma ou électrons au site malade pour la production de ladite lumière ultraviolette ou visible au niveau du site malade pour activer le médicament photoactivable.
Patent CA-2946694-A1 (CA)
Inventor: LANIADO AMIR
IPC: A61F5/443
Filed: 2014-08-14
Abstract: The present invention relates to an external urinary incontinence treatment a device and a method of deploying an external urinary incontinence treatment device that minimizes the inconvenience of fastening and fixating a urine receiving component to the genital region and to the skin surrounding the urethral orifice of a treated patient. The device comprises: a urine receiving component, a tube, a receiving component supporting element, a tube locking system, a genital region connection component, and a genital region anchoring element. The tube connects and communicates freely with the urine receiving component and is inserted through the receiving component supporting element. The tube also communicates with said tube locking system and is able to move vertically the receiving component supporting element when said tube locking system is deactivated. The tube is fixated in its movement at a desired position along the length of said tube when said tube locking system is activated. The device receiving component supporting element is connected to the genital region connection component and with the tube locking system. The genital region connection component is connected to the genital region anchoring element. In deployment of the device, the genital region anchoring element is reversibly connected to the skin of the genital region of the treated patient, and urine receiving-component is connected to the skin surrounding the urethral orifice of the treated patient when the tube is moved towards the genital region of the patient. The tube is reversibly fixated in place by the tube locking system after urine receiving component is adjusted and fastened to the skin surrounding the urethral orifice of the patient in a urine leak free connection while applying the minimal required pressure, thus, causing the treated patient minimal inconvenience. The tube lucking system can be easily deactivated and reactivated to adjust the connection of the receiving component to the skin surrounding the urethral orifice in accordance to changing body postures of the patient.
Patent CA-2951572-A1 (CA)
Title: Media bed filters for filtering fine particles from a raw liquid flow and method of using the same
Inventor: BOSISIO MARCO
IPC: B01D24/02
Filed: 2013-07-16
Abstract: The present document describes a media bed filter for filtering fine particles from a raw liquid flow, the media bed filter comprising: a tank having: a top portion; a bottom portion defining a bottom surface for receiving a media bed, the media bed having a supporting media to be disposed on the bottom surface and a filtering media for covering the supporting media, the top portion of the tank being above the filtering media of the media bed; a raw liquid inlet in fluid communication with a nozzle configuration located in the top portion of the tank for providing the raw liquid flow in the tank in the form of a plurality of jets at a directional velocity substantially equal or greater to a disengagement velocity of the filtering media.
Patent CA-2952758-A1 (CA)
Title: Anticorps se liant a axl
Inventor: BREIJ ESTHER
IPC: A61P35/00
Filed: 2015-07-10
Abstract: La présente invention concerne des anticorps anti-AXL, des immunoconjugués, des compositions et une méthode de traitement du cancer faisant intervenir lesdits anticorps anti-AXL, immunoconjugués ou compositions.
Patent CA-2954639-A1 (CA)
Title: Producing lithium
Inventor: SWONGER LAWRENCE RALPH
IPC: C25C7/04
Filed: 2015-07-09
Abstract: The present disclosure generally relates to an electrolytic process for continuous production of lithium metal from lithium carbonate or other lithium salts by use of an aqueous acid electrolyte and a lithium producing cell structure. The lithium producing cell structure includes: a cell body with a cathode within the cell body; a sulfuric acid solution within the cell body, the solution containing lithium ions; and a composite layer intercalated between the cathode and the electrolyte aqueous solution, the composite layer comprising a lithium ion conductive glass ceramic (LI-GC) and a lithium ion conductive barrier film (LI-BF) that isolates cathode-forming lithium from the electrolyte aqueous solution.
Patent CA-2954738-A1 (CA)
Inventor: MAIER MARCEL
IPC: C07K14/47
Filed: 2015-07-29
Abstract: Provided are novel human-derived anti-huntingtin (HTT) antibodies and biotechnological derivatives thereof, preferably capable of binding mutated and/or aggregated HTT species and or fragments thereof, as well as methods related thereto. The human-derived anti-HTT antibodies and biotechnological derivatives can be used in pharmaceutical and diagnostic compositions for HTT targeted immunotherapy of Huntington Disease and diagnosis thereof.
Patent CA-2955493-A1 (CA)
Title: Oral care compositions and regimens
Inventor: SAGEL PAUL ALBERT
IPC: A61K8/22
Filed: 2015-08-11
Abstract: Compositions and methods for improving compliance with a two-part oral care regimen may include the use of a first composition with mildly unpleasant organoleptic properties.
Patent CA-2959796-A1 (CA)
Inventor: VILKOV ANDREY N
IPC: G01N27/62
Filed: 2017-03-03
Abstract: The present disclosure is directed to methods and systems for detecting a chemical substance. The methods and systems include chemically modifying a sample of a substance of interest through combination with a reagent to increase the volatility of the substance of interest. The systems and methods further include performing an analysis of the substance of interest.
Patent CA-2966475-A1 (CA)
Inventor: MAEJIMA YOZO
IPC: D06F67/04
Filed: 2015-04-17
Abstract: [Task] Provided is a buffering device in an automatic cloth feeder that includes a cloth standby section in which cloth stands by temporarily, and accumulates the cloth. [Means for Resolution] There is provided a cloth supply section 11 that can supply a quantity of cloth exceeding a processing quantity of feeding so as to proceed with feeding in an automatic cloth feeder 10 without congestion in the automatic cloth feeder performing a process in which the cloth is introduced to a feeding conveyor at a substantially central portion in a carrying direction, right and left trailing end portions are detected by crumpling the cloth from the right and left sides, the cloth is held in a deposition section, and the cloth is fed into a process. A cloth standby section 14 in which the cloth to be carried stands by temporarily is set at a preceding stage of a feeding conveyor 20 or at a following stage thereof.
Patent CA-2967952-A1 (CA)
Inventor: MAJEED MUHAMMED
IPC: A61P1/12
Filed: 2016-01-07
Abstract: The present invention discloses a process for the therapeutic management of diarrhea predominant irritable bowel syndrome in humans comprising the oral administration of Bacillus coagulans SBC37-01, MTCC 5856 (containing not less than 2 billion spores) along with standard treatment of care in a specific manner.
Patent CA-2968221-A1 (CA)
Inventor: SCHAEFER ERNST J
IPC: A61B5/0205
Filed: 2015-11-17
Abstract: The invention provides improved methods for analyzing cardiovascular disease risk. According to the invention, an algorithm that considers LDL and HDL subfractions, along with Lp(a) provides significant improvement in predicting CVD versus standard assays that include standard risk factors. Methods of the invention comprise measuring LDL and HDL subfractions in addition to Lp(a) without reference to standard risk factor measurements, such as CRP, total cholesterol, body mass index, weight, triglycerides, and the like. It is unexpected that an algorithm focusing only on LDL and HDL subfractions and Lp(a) would be more informative as to CVD risk than measurements that are much more comprehensive in terms of the markers that are reviewed. In particular, the sdLDL-C subfraction of LDL and the ApoA- 1 in large alpha- 1 HDL are most informative in conjunction with Lp(a).
Patent CA-2969651-A1 (CA)
Inventor: ZHANG YANSHI
IPC: C10M129/16
Filed: 2015-12-03
Abstract: The disclosed technology provides lubricating composition comprising: an oil of lubricating viscosity, a p-dodecylphenol-free detergent and an oxyalkylated hydrocarbyl phenol, wherein the oxyalkylated hydrocarbyl phenol is substituted with at least one aliphatic hydrocarbyl group of 1 to 250 carbon atoms (or 20 to 220, or 30 to 150 carbon atoms), and wherein the oxyalkylated hydrocarbyl phenol is substantially free of aromatic hydrocarbyl groups. The disclosed technology further relates to a method of lubricating a mechanical device (such as an internal combustion engine) with the lubricating composition. The disclosed technology further relates to the use of the of the lubricating composition in a passenger car internal combustion engine to improve control of at least one of the following (i) fuel economy, (ii) corrosion, (iii) cleanliness, and (iv) bore wear.
Patent CA-2973083-A1 (CA)
Title: Pouch with sealed fitment and method
Inventor: PY DANIEL
IPC: A61J1/10
Filed: 2016-01-07
Abstract: A pouch comprises a film including (i) a fold defining a fold plane and a first marginal edge portion of the pouch, (ii) a first side transverse to the fold plane, and (iii) a second side opposite the first side and transverse to the fold plane. A fitment of the pouch includes a port and a base. The base defines a mid-portion engaging the fold at the fold plane, a first side located on one side of the mid-portion, and a second side located on an opposite side of the mid- portion relative to the first side. The first and second sides of the base are transverse to the fold plane, and are engaged with the first or second sides of the film, respectively. The base or film overlaps the other and defines an overlapping region. The base and film are sealed to each other within the overlapping region and form a fluid-tight seal that extends about the port.
Patent CA-2974135-A1 (CA)
Inventor: LINCECUM JOHN M
IPC: A61K39/395
Filed: 2016-02-02
Abstract: Anti-human CD40L antibodies engineered to lack the ability to activate platelets and methods for treating patients having a CD40L-associated disease.
Patent CA-2974229-A1 (CA)
Inventor: WONDRACZEK LOTHAR
IPC: A61C13/083
Filed: 2016-01-29
Abstract: The invention relates to a method for the production of a medical form body comprising or containing a lithium silicate glass ceramic. To allow the strength of the form body to be increased compared to the prior art, it is proposed that in a preform body comprising or containing a lithium silicate glass ceramic with a geometry that corresponds to the form body a surface compressive stress is created by replacement of lithium ions with alkali ions of greater diameter, wherein after substitution of the ions the preform body is used as the form body.
Patent CA-2975486-A1 (CA)
Inventor: WHITE JAMES FRANCIS
IPC: A01N63/27
Filed: 2017-08-04
Abstract: Endophytic bacteria, compositions comprising the same, and methods of use thereof are disclosed which increase the root and shoot growth of cotton host plants, suppress growth of soil borne fungal pathogens of host plants, and increase resistance of the plant to salt stress and other abiotic stressors.
Patent CA-2977039-A1 (CA)
Inventor: LASKAR WILLIAM JOSEPH
IPC: A01H1/00
Filed: 2017-08-23
Abstract: A wheat variety designated A060013G1, the plants and seeds of wheat variety A060013G1, methods for producing a wheat plant produced by crossing the variety A060013G1 with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety A060013G1 with another wheat line or plant, and the creation of variants by backcrossing, mutagenesis or transformation of variety A060013G1 are disclosed. Methods for producing other wheat varieties or breeding lines derived from wheat variety A060013G1 and to wheat varieties or breeding lines produced by those methods are also provided.
Patent CA-2977473-A1 (CA)
Inventor: SILVER MATTHEW
IPC: H01M8/04313
Filed: 2010-02-24
Abstract: The invention relates to bio-electrochemical systems for the generation of methane from organic material and for reducing chemical oxygen demand and nitrogenous waste through denitrification. The invention further relates to an electrode for use in, and a system for, the adaptive control of bio-electrochemical systems as well as a fuel cell.
Patent CA-2979419-A1 (CA)
Inventor: JIN PU
IPC: B60L50/15
Filed: 2016-01-13
Abstract: A range extender vehicle comprises: a turboshaft engine (1) arranged on a vehicle frame (12) chassis, a turboshaft engine controller (2), a generator (3), a battery pack (4), a battery controller (5), a driving motor (6), a battery heat radiator (7), and a gas storage tank (9). A signal end of the turboshaft engine (1) is connected to the turboshaft engine controller (2). A transmission shaft (1-6) is connected to a rotatory shaft of the generator (3). The generator (3) outputs an electric energy to the battery pack (4) and the driving motor (6) respectively. The battery pack (4) and the driving motor (6) are connected together and are connected to the battery controller (5) at the signal end. The transmission shaft of the driving motor (6) is connected to wheels (11). A cold air channel of the battery heat radiator (7) leads to the battery pack (4). A gas pipeline of the gas storage tank (9) is connected to a gas inlet pipeline of the turboshaft engine (1). The present invention forms a highly efficient, stable, and environmental friendly system, and has advantages of a high power to weight ratio, a low power consumption, a low emission, a low noise and vibration, eliminating the need for an exhaust gas treatment system and being easy to maintain, and having a long serving life.
Patent CA-2980466-A1 (CA)
Title: Pedestrian protection automotive hinge
Inventor: PATTERSON PATRICK
IPC: B60R21/38
Filed: 2016-06-03
Abstract: A pedestrian protection automotive hinge includes a release assembly which includes a clip supported at one of the first and second opposing ends of a slot in one of first and second members, and a stop pin supported by the other of the first and second members. The stop pin is captured in the clip in the normally closed position and the normally opened position. An actuator is configured to engage the second member and to force the second member upward relative to the first member in response to a collision input. The stop pin is configured to break the clip in response to this force permitting the second member to pivot about a member pin relative to the first member to an opened hood collision position and the stop pin to move to the end of the slot opposite the clip.
Patent CA-2980492-A1 (CA)
Title: Method for evaluating the level of threat
Inventor: LABREUCHE CHRISTOPHE
IPC: F41H11/00
Filed: 2016-03-23
Abstract: The present invention concerns a method for evaluating the level of threat of at least one entity (SE) among a plurality of entities in a battlefield environment, the level of threat being evaluated with respect to a reference entity (RE) to be protected, the method comprising the steps of: - segmenting the battlefield environment into a plurality of layers (L1, L2, L3, L4, L5), - obtaining data representative of a position of said entity (SE) with respect to the layers (L1, L2, L3, L4, L5) of the battlefield environment, and - determining the level of threat of said entity (SE) using the obtained data.