baber/WOPTO huggingface dataset:
Patent ES-2284941-T3 (ES)
Inventor: BETTATI MICHELA
IPC: C07D487/04
Filed: 2002-11-27
Granted: 2007-11-16
Abstract: The present invention provides a pharmaceutical composition providing a compound of formula I or a pharmaceutically acceptable salt thereof in a pharmaceutically acceptable excipient: (I), in which: X and Y independently represent CH or N, with the proviso that if X is CH then Y is also CH; R<SUP>1 </SUP>represents hydrogen, hydrocarbon, a heterocyclic group, halogen, cyano, trifluoromethyl, nitro, -OR<SUP>a</SUP>, -SR<SUP>a</SUP>, -SOR<SUP>a</SUP>, -SO<SUB>2</SUB>R<SUP>a</SUP>, -SO<SUB>2</SUB>NR<SUP>a</SUP>R<SUP>b</SUP>, -NR<SUP>a</SUP>R<SUP>b</SUP>, -NR<SUP>a</SUP>COR<SUP>b</SUP>, -NR<SUP>a</SUP>CO<SUB>2</SUB>R<SUP>b</SUP>, -COR<SUP>a</SUP>, -CO<SUB>2</SUB>R<SUP>a</SUP>, -CONR<SUP>a</SUP>R<SUP>b </SUP>or CR<SUP>a</SUP>-NOR<SUP>b</SUP>; R<SUP>a </SUP>and R<SUP>b </SUP>independently represent hydrogen, hydrocarbon or a heterocyclic group; V and W are independently selected from H, halogen, C<SUB>11-6</SUB>alkyl, OH and C<SUB>-1-6</SUB>alkoxy; Z represents H, halogen, CN, NO<SUB>2</SUB>, CF<SUB>3</SUB>, OCF<SUB>3</SUB>, CF<SUB>2</SUB>H, SCF<SUB>3</SUB>, R<SUP>2</SUP>, OR<SUP>3</SUP>, SR<SUP>3</SUP>, (CH<SUB>2</SUB>)pN(R<SUP>3</SUP>)<SUB>2</SUB>, O(CH<SUB>2</SUB>)pN(R<SUP>3</SUP>)<SUB>2</SUB>, SO<SUB>2</SUB>R<SUP>2</SUP>, SO<SUB>2</SUB>N(R<SUP>3</SUP>)<SUB>2</SUB>, COR<SUP>4</SUP>, CO<SUB>2</SUB>R<SUP>3</SUP>, CON(R<SUP>3</SUP>)<SUB>2</SUB>, NHCOR<SUP>4</SUP>, NR<SUP>1</SUP>(CH<SUB>2</SUB>)<SUB>n</SUB>heteroaryl or O(CH<SUB>2</SUB>)<SUB>n</SUB>heteroaryl the heteroaryl is optionally substituted by one, two or three groups chosen from C<SUB>1-6</SUB>alkyl, benzyl, (CH<SUB>2</SUB>)pN(R<SUP>3</SUP>)<SUB>2</SUB>, halogen and CF<SUB>3</SUB>, R<SUP>1 </SUP>is C<SUB>1-6</SUB>alkyl, where n is 1 or 2 and p is 0, 1 or 2; with the proviso that at least one of V, W and Z is other than H; R<SUB>2 </SUB>represents C<SUB>1-6</SUB>alkyl, C<SUB>3-6</SUB>cycloalkyl, C<SUB>3-6</SUB>cycloalkylC<SUB>1-4</SUB>alkyl, C<SUB>2-6</SUB>alkenyl, C<SUB>2-6</SUB>alkynyl or heteroaryl, any of which may bear a substituent selected from halogen, CN, NO<SUB>2</SUB>, CF<SUB>3</SUB>, OCF<SUB>3</SUB>, CF<SUB>2</SUB>H, SCF<SUB>3</SUB>, OH, C<SUB>1-4</SUB>alkoxy, C<SUB>1-4</SUB>alkoxycarbonyl, amino, C<SUB>1-4</SUB>alkylamino, or di(C<SUB>1-4</SUB>alkyl)amino; R<SUP>3 </SUP>represents H or R<SUP>2</SUP>; or two R<SUP>3 </SUP>groups bonded to the same nitrogen atom may complete a 5-7 membered nonaromatic heterocyclic ring; and R<SUP>4 </SUP>represents R<SUP>3 </SUP>or heteroaryl; the compounds are ligands for GABA-A receptors containing the alpha 5 subtype and thus are useful for enhancing cognition in individuals suffering from conditions such as Alzheimer's Disease.
Patent ES-2374973-T3 (ES)
Inventor: ZIEGLER HUGO
IPC: C07K5/068
Filed: 2002-12-06
Granted: 2012-02-23
Abstract: The invention relates to compounds of general formula (I) and acid addition salts thereof, where the various symbols have the meanings given in the description and claims, the production and use thereof as substrate for the detection of TAFIa, a fibrinolysis inhibiting enzyme. The detection occurs by using the absorption between 400 and 412 nm, arising as a result of the formation of 3-carboxy-4-nitrothiophenol from Ellman's reagent as a function of time.
Patent ES-2306803-T3 (ES)
Title: Composiciones y procedimientos de tratamiento de yeso endurecido.
Inventor: YU QIANG
IPC: C04B41/50
Filed: 2002-11-19
Granted: 2008-11-16
Abstract: Una composición acuosa para revestir un material que contiene yeso endurecido, composición formada por como mínimo: agua; como mínimo una sal fosfato monobásico; como mínimo una sal trimetafosfato, y como mínimo una sal polifosfato acíclico que tiene como mínimo 3 unidades fosfato.
Patent ES-2262887-T3 (ES)
Inventor: MANCINI VASCO
IPC: E01H1/12
Filed: 2002-12-17
Granted: 2006-12-01
Abstract: A leash is disclosed, which comprises a wire-shaped or band-shaped, relatively flexible member with a first end for attachment to a pet collar or harness, and a handle for grasping the other end of the wire-shaped or band-shaped member. The leash handle has a relatively rigid body. The leash also includes a device for collecting animal excre-ment releasably connected to the rigid body so as not to interfere with normal use of the leash. Preferably, the device for collecting excrement comprises a scoop inserted flush within a seating formed in the body, a snap fastener being arranged between the seating and the scoop to secure the latter in the inserted position.
Patent ES-2272814-T3 (ES)
Inventor: EVERSHEIM HUBERTUS
IPC: A61Q1/04
Filed: 2002-11-12
Granted: 2007-05-01
Abstract: Cosmetic formulations comprising alkyl-substituted siloxanes as vaporizable carriers.
Patent ES-2331357-T3 (ES)
Title: Metodo y dispositivo para unir componentes metalicos, en particular componentes metalicos ligeros.
Inventor: GRONG OYSTEIN
IPC: B23K103/10
Filed: 2002-11-19
Granted: 2009-12-30
Abstract: Método para unir componentes de metales y aleaciones, en particular componentes de metales ligeros, incluyendo aleaciones de metales ligeros y posiblemente híbridos/compuestos que comprenden metales ligeros, caracterizado porque se retira el óxido de las superficies de ranura inmediatamente antes de la unión y porque a continuación se rellena la ranura mediante extrusión con un material de relleno metálico mientras se restringe simultáneamente el suministro de oxígeno a la ranura en la medida en que se requiera.
Patent ES-2395025-T3 (ES)
Title: Lanza misiles con conductos de salida de gas
Inventor: CIAPPI JORGE
IPC: F41F3/052
Filed: 2002-06-26
Granted: 2013-02-07
Abstract: Un lanzador de misiles (10a) para aceptar un misil (512), comprendiendo el lanzador de misiles (10a) un entubadode misil (510), el entubado del misil (510) define un extremo de lanzamiento del misil y un extremo de escape delmisil, para, previamente al lanzamiento del misil, mantener el lanzador de misiles (10a) en dicho entubado de misil(510) en una posición de lanzamiento generalmente vertical por debajo de la cubierta (16ad), comprendiendoadicionalmente dicho lanzador de misiles (10a):al menos una chimenea de gases de escape redonda alargada (30a1);un estructura de soporte (12a) que define una cavidad en general axial que define un extremo de lanzamientodel misil y un extremo de escape del misil, teniendo dicha cavidad de dicha estructura de soporte (12a) unalongitud y unas dimensiones de sección transversal capaces de alojar dicho entubado de misil (510),una distribución de escape del misil (40a) fijada cerca de dicho extremo de escape del misil de dicha estructurade soporte (12a), estando acoplado dicho escape del misil (40a) a dicha al menos una chimenea de gases deescape redonda alargada (30a1) cerca de dicho extremo de escape del misil de dicha estructura de soporte(12a), incluyendo adicionalmente dicha distribución de escape del misil (40a) medios de fijación para la fijacióna dicho extremo de escape del misil de dicho entubado de misil (510), para el encaminado de los gases deescape del misil desde dicho extremo de escape del misil de dicha estructura de soporte (12a) a dicha almenos una chimenea de gases de escape redonda alargada (30a1), para hacer que los gases de escape delmisil ventilen desde dicha al menos una chimenea de gases de escape redonda alargada (30a1) a cerca dedicho extremo de lanzamiento del misil de dicha estructura de soporte (12a) yuna estructura de compuerta (16dh) fijada a dicho extremo de lanzamiento del misil de dicha estructura desoporte (12a), para, cuando está cerrada, proteger al menos dicha estructura de soporte (12a), dicha al menosuna chimenea de gases de escape redonda alargada (30a1) y cualquier entubado de misil (510) alojado dentrode dicha cavidad y para, cuando está abierta, proporcionar una liberación para lanzamiento de dicho misil (512)y para la ventilación de dichos gases de escape desde dicha al menos una chimenea de gases de escaperedonda alargada (30a1)caracterizado por quedicha al menos una chimenea de escape (30a1) se dispone en el exterior y al mismo tiempo a lo largo delexterior de dicha estructura de soporte (12a) que se extiende, en paralelo con dicho eje de dicha cavidad,desde cerca de dicho extremo de lanzamiento del misil a cerca de dicho extremo de escape del misil.
Patent ES-2225805-T3 (ES)
Inventor: PRUNBAUER KURT
IPC: E05B19/02
Filed: 2003-03-24
Granted: 2005-03-16
Abstract: Key for a cylinder lock has a key shaft (3) with at least three control grooves (4-6) running primarily along the shaft insertion direction so that they also intersect in a number of points. One of the grooves (6) is deeper than the remaining three. The key shaft is essentially cylindrical and the grooves are cut into it.  The invention also relates to a corresponding cylinder lock.
Patent ES-2231746-T3 (ES)
Title: Dispositivo y procedimiento para el ajuste manual en altura de la superficie de carga de un vehiculo automovil.
Inventor: DIETERLE MICHAEL
IPC: B60R5/04
Filed: 2003-07-01
Granted: 2005-05-16
Abstract: Dispositivo (1) para la guía de la superficie de carga de un vehículo automóvil, la cual puede ser ajustada en su altura; con por lo menos una vía de guía (5), dentro de la cual se encuentra guiado en su desplazamiento por lo menos un elemento de guía (1) de la superficie de carga; en este caso, la vía de guía (5) posee un tramo de vía de guía (9), que se extiende de forma oblicua con respecto a una línea horizontal imaginaria (H), y el mismo está dispuesto entre una posición inferior y una posición superior de la superficie de carga; dispositivo éste que está caracterizado porque la vía de guía (5) tiene un bloqueo de retroceso (17) que, durante el desplazamiento de la superficie de carga desde la posición inferior hacia la posición superior, bloquea el tramo oblicuo (9) de la vía de guía al ser alcanzada una posición intermedia o bien al ser atravesada esta posición intermedia.
Patent ES-2246462-T3 (ES)
Title: Normalizacion del marcador de verificacion en un aparato para verificacion del hablante.
Inventor: CHARLET DELPHINE
IPC: G10L17/12
Filed: 2003-07-10
Granted: 2006-02-16
Abstract: Un dispositivo para reconocer automáticamente la voz de un locutor autorizado para acceder a una aplicación (AP), que comprende un medio (A1, A2, A3) para generar parámetros (m) de un modelo vocal de aceptación (A) respecto a un segmento vocal (MP) pronunciado por el locutor autorizado y parámetros (m) de un modelo vocal de rechazo (W) previamente durante una fase de aprendizaje, un medio (V1, V2, V3) para normalizar por parámetros de normalización un resultado de verificación de locutor dependiendo de la relación de verosimilitudes entre un segmento vocal a probar (X) y los modelos de aceptación y de rechazo, y un medio (V4) para comparar el resultado de verificación normalizado (SN) a un primer umbral (TH1) a fin de no autorizar el acceso del locutor que ha pronunciado el segmento vocal a probar a la aplicación (AP) más que si el resultado normalizado es al menos tan grande como el primer umbral, caracterizado porque comprende un medio (V6) para actualizar al menos uno de los parámetros de normalización en función de un valor precedente de dicho parámetro y del resultado de verificación de locutor (SV) en cada prueba de segmento vocal solamente cuando el resultado normalizado (SN) es al menos igual a un segundo umbral (TH2) que es al menos igual al primer umbral (TH1).
Patent ES-2298489-T3 (ES)
Inventor: UGARTE BILBAO ALBERTO
IPC: C22B1/245
Filed: 2003-09-24
Granted: 2008-05-16
Abstract: The steelworks dust, comprising iron oxides 20/50% is mixed with calcium oxide 2/9%, zinc oxide 10/45% and lead oxides 4/15%, at a particle size less than 150 microns, in a mixer causing homogenization.
Patent ES-2353208-T3 (ES)
Inventor: CALZADA NOVA LUIS ANTONIO
IPC: A61K35/15
Filed: 2003-02-26
Granted: 2011-02-28
Abstract: The present invention relates to a pharmacological compound which is made with the soluble dialyzed extract of leukocyte lysates of animal origin. Said leukocyte lysates are obtained from sanguineous or lymphatic tissue from sensitized or not sensitized domestic animals with specific antigens for their application in animals in the treatment of infectious diseases, such as canine distemper.
Patent ES-2285120-T3 (ES)
Inventor: KONZ JOHN O JR
IPC: C12N15/861
Filed: 2003-05-13
Granted: 2007-11-16
Abstract: A process for purifying virus particles, especially recombinant adenovirus vector particles, is presented. The process relies on various combinations of cell lysis, detergent-based precipitation of host cell contaminants away from the virus, depth filtration or centrifugation, ultrafiltration, nuclease digestion and chromatography to robustly and economically produce highly purified product. This process results in contaminating DNA levels which are consistently below detectable levels.
Patent ES-2287493-T3 (ES)
Inventor: NYANDER ANDERS
IPC: B05B15/68
Filed: 2003-07-08
Granted: 2007-12-16
Abstract: The invention relates to a device for the application of a fluid. The device is intended to be mounted as a tool on a holder which is adjustable between different positions and directions. The device comprises preferably at least two nozzles (12) for discharge of said fluid, one product valve means (4) associated with each nozzle for control of the supply of fluid to each nozzle, a swivel means (2) which connects the holder to a rotatable nozzle head carrying said nozzles. Two channels are preferably arranged through said swivel means (2) for establishing fluid communication between the holder and the rotatable nozzle head. According to the invention the product valve means (4) are arranged in the rotatable nozzle head. This means that channels in the swivel (2) may be used for inlet and return channels enabling circulation up to the product valves (4) located close to the nozzles (12). The feature also allows the channels in the swivel to be used for separate fluids enabling mixing at the nozzle head for two-component application of fluids or enabling application of two different fluid materials.
Patent ES-2273058-T3 (ES)
Inventor: HOFFMANN MICHAEL
IPC: H01R4/38
Filed: 2003-11-10
Granted: 2007-05-01
Abstract: A tubular reflective housing (12) contains a cylindrical heating element (11) fixed to the base (15) by a screw (16) to heat material flowing to the jet (13). Electrical leads (17) terminate in contacts (26) held against the element by threaded fastenings (22) having insulators (19).
Patent ES-2309404-T3 (ES)
Inventor: JENSEN TIM
IPC: A61F13/20
Filed: 2004-02-05
Granted: 2008-12-16
Abstract: A tampon for feminine hygiene that has an insertion end, a withdrawal end, a central portion between the insertion end and the withdrawal end, a length, a longitudinal axis, a radial axis, and an outer surface. The tampon is made of compressed fibrous material. The outer surface of the insertion end has a plurality of longitudinal grooves which are offset from the plurality of longitudinal grooves located in the withdrawal end. <IMAGE>
Patent ES-2298659-T3 (ES)
Inventor: SAUERMANN HANS
IPC: B60D1/28
Filed: 2004-10-01
Granted: 2008-05-16
Abstract: A tractor has a tow hook (1) has a ball head (6) which engages with the trailer drawbar (4). The ball head forms part of an adjustable support (7) that is fixed to a cam (9) that may be engaged or disengaged from the trailer drawbar.
Patent ES-2380545-T3 (ES)
Inventor: VAN T HOFF JAAP HERMAN
IPC: B65D83/14
Filed: 1999-05-31
Granted: 2012-05-16
Abstract: A pressure control device for maintaining a constant predetermined excess pressure in a fluid dispensing container, which device comprises a first chamber, a fluid connection between the first chamber and the container, a valve with a closing member for releasing and closing said fluid connection and a resilient pressure element exerting said predetermined excess pressure onto the closing member in closing direction, the resilient pressure element comprising a second chamber being filled with a gas at the predetermined excess pressure and relative to which the closing member is movable, the first chamber being filled with a gas at a pressure higher than said predetermined excess pressure, while in use the fluid connection is released if the fluid pressure in the container drops below the predetermined excess pressure, so that gas flows from the first chamber to the container and the pressure in the container increases until the fluid connection is closed again by the closing member as a result of the increased pressure in the container, characterized that the closing member is movable in a reciprocated manner between an upper extreme position and a lower extreme position, whereby the fluid connection is closed, which extreme positions are defined by the width of a circumferential recess in the valve and the release position of the closing member is defined between the upper and lower closing positions. <IMAGE>
Patent ES-2289426-T3 (ES)
Title: Adenovirus recombinante humano de serotipo 35.
Inventor: BOUT ABRAHAM
IPC: A61K39/00
Filed: 2000-05-16
Granted: 2008-02-01
Abstract: Un adenovirus recombinante, donde dicho adenovirus es un adenovirus humano de serotipo 35 (Ad35).
Patent ES-2364247-T3 (ES)
Inventor: HAIDER M ISHAQ
IPC: A61M5/24
Filed: 2004-01-07
Granted: 2011-08-29
Abstract: An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the locking mechanism prevents the needle from being placed in the injection position.
Patent ES-2389161-T3 (ES)
Title: Polímero de butadieno y procedimiento para producirlo, y composición de caucho y neumático que la comprende o fabricado a partir de ella
Inventor: SUZUKI EIJU
IPC: C08F4/611
Filed: 2004-06-23
Granted: 2012-10-23
Abstract: Un polímero basado en butadieno que presenta una unidad de monómero de 1,3-butadieno, que se caracterizapor que el contenido de enlace cis-1,4 y el contenido de enlace de vinilo en la unidad de monómero de 1-3-butadieno, medidos por medio de espectroscopia de infrarrojos de transformada de Fourier (FT-IR) no es menor que98,0 % y no es mayor que 0,3 %, respectivamente, y la proporción (M w/Mn) de peso molecular medio expresado enpeso (Mw) con respecto a peso molecular medio expresado en número (Mn) es de 1,6-3,5.
Patent ES-2320892-T3 (ES)
Inventor: GYORY RICHARD J
IPC: A61N1/30
Filed: 2004-03-30
Granted: 2009-05-29
Abstract: This invention relates to an electrotransport device, which incorporates a flexible conductive element within the reservoir housing of the device, which permits electrical communication from within the housing to outside of the housing without the use of opening, which require various methods of sealing the opening against leaks and moisture.
Patent ES-2273282-T3 (ES)
Inventor: LIU KEVIN
IPC: C07D213/74
Filed: 2004-04-07
Granted: 2007-05-01
Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
Patent ES-2325993-T3 (ES)
Inventor: SILVA ANA CLAUDIA R
IPC: C12N7/02
Filed: 2004-09-20
Granted: 2009-09-28
Abstract: The present disclosure relates to nucleic acid molecules comprising the genome of the Citrus Sudden Death Virus (CSDV), the causative agent of Citrus Sudden Death (CSD) disease. The cloned CSDV nucleic acid molecules can be used as probes or can be used to design oligonucleotide primers useful in assays, such as a polymerase chain reaction, for detecting the presence of CSDV in biological samples, particularly leaves, roots and other tissues or organs of plants, such as plants from the genera Citrus and Poncirus. The disclosure also comprises the nucleic CSDV nucleic acid molecules, in whole or part, as well as transgenic plants, such as monocots and dicots, containing the CSDV nucleic acid molecules, in any kind of combination, so that expression increases resistance to CSD disease.
Patent ES-2383042-T3 (ES)
Inventor: PRASAD DILIP
IPC: B66B15/04
Filed: 2004-08-04
Granted: 2012-06-15
Abstract: A sheave for use in an elevator system comprises a sheave body (22) having a central axis (34) and a belt guiding surface (26) including a surface profile extending in an axial direction along at least a portion of the belt guiding surface (26). The surface profile has a central portion (42), first side portions (44, 46) extending away from opposite edges of the central portion (42) toward corresponding edges of the sheave and second side portions (48, 50) extending away from the first side portions (44, 46) toward the corresponding edges of the sheave. The central portion (42) has a parallel alignment with the sheave central axis (34), the first side portions (44, 46) have a curved profile and the second side portions (48, 50) have a linear profile.
Patent ES-2300823-T3 (ES)
Inventor: KALHAN AMIT
IPC: H04L12/28
Filed: 2004-08-19
Granted: 2008-06-16
Abstract: A system and method are described for determining when to exit an existing wireless communication coverage network. The method samples the device geographical position, determines a threshold boundary line, measures the position of each sample point with respect to the threshold boundary line, and, beginning at a predetermined initial value, maintains a running sum in response to measuring position. The existing coverage network is exited when the running sum is greater than or equal to a predetermined terminal value.
Patent ES-2289575-T3 (ES)
Title: Un aparato y metodo para girar recipientes.
Inventor: PERSSON RICHARD
IPC: B65B/
Filed: 2004-11-24
Granted: 2008-02-01
Abstract: Un aparato (10) que comprende un mecanismo de giro que está destinado a modificar la orientación de un cierto número de recipientes de envasado (12) en movimiento dentro de una máquina de llenado, de una primera orientación (20) a una segunda orientación (22), que comprende un transportador (26), provisto de al menos un portador (28) al que está unida al menos una unidad portadora (58), de tal manera que la unidad portadora (58) es rotativa con respecto al portador (28) en torno a un eje geométrico de rotación (A) y está destinada a portar el recipiente de envasado (12) de tal manera que el centro de gravedad del recipiente de envasado durante el cambio de orientación esté situado sustancialmente en el eje geométrico de rotación (A); y de forma que el centro de gravedad del recipiente de envasado conserve, con ello, sustancialmente la misma dirección de desplazamiento y velocidad de la primera a la segunda orientaciones (20, 22), caracterizado por que la unidad portadora (58) está provistade un par de porciones de dedo (72) destinadas a portar recipientes de envasado (12) cuyas pestañas (14) de esquina sobresalen o apuntan hacia fuera sustancialmente rectas desde los lados de los recipientes de envasado, y por que las porciones de dedo (72) de la unidad portadora están diseñadas de modo que sean capaces de portar el recipiente de envasado (12) mediante contacto a tope bajo estas pestañas (14) de esquina.
Patent ES-2300874-T3 (ES)
Inventor: ISSON OLIVIER
IPC: H04L27/26
Filed: 2004-09-15
Granted: 2008-06-16
Abstract: The method involves determining two vectors from signals received by a receiver. A correlation and a square error between the vectors are calculated. A cost function (F1) that is a linear combination of two previous cost functions is calculated, and according to sign of result, another cost function is calculated to estimate an initial frame, and the receiver is activated. An independent claim is also included for a device to control a receiver in a digital communication system.