baber/WOPTO huggingface dataset:
Patent SI-2558867-T1 (SI)
Title: Method for differentially quantifying naturally processed hla-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
Inventor: WEINSCHENK TONI
IPC: G01N33/00
Filed: 2011-04-15
Abstract: The invention relates to a method for quantitatively identifying relevant HLA-bound peptide antigens from primary tissue specimens on a large scale without labeling approaches. This method can not only be used for the development of peptide vaccines, but is also highly valuable for a molecularly defined immunomonitoring and the identification of new antigens for any immunotherapeutic strategy in which HLA-restricted antigenic determinants function as targets, such as a variety of subunit vaccines or adoptive T-cell transfer approaches in cancer, or infectious and autoimmune diseases.
Patent SI-2686002-T1 (SI)
Title: Method for reducing flu-like symptoms associated with intramuscular administration of interferon using a fast titration escalating dosing regimen
Inventor: DEYKIN AARON
IPC: A61P25/00
Filed: 2012-03-15
Abstract: The present invention provides a method for treating multiple sclerosis (MS), and for reducing flu-like symptoms associated with administration of an interferon to a patient with MS. The method involves intramuscularly administering the interferon to the MS patient according to an escalating dosing regimen in weeks 1 to 3, and a full therapeutically effective dose of interferon in week 4. In one embodiment of the invention, the escalating dosing regimen comprises administering one quarter of the therapeutically effective dose in week 1, half of the therapeutically effective dose in week 2, and three-quarters of the therapeutically effective dose in week 3. Also provided are titration packages for enabling compliance with a regimen of changing dosage of an interferon over a period of time.
Patent SI-2850431-T1 (SI)
Title: Vaccines for hsv-2
Inventor: DUBENSKY THOMAS W JR
IPC: C07K14/00
Filed: 2013-05-16
Abstract: Compositions of recombinant HSV-2 proteins and an agonist of the innate immune system, such as an adjuvant, are provided as a vaccine. Proteins include an envelope glycoprotein and a structural protein other than an envelope glycoprotein, e.g., a capsid or tegument protein. The vaccine is for use in either HSV-2 seropositive or seronegative subjects.
Patent DE-3588216-T2 (DE)
Inventor: HARTMAN JACOB R
IPC: C12N15/73
Filed: 1985-08-26
Granted: 2000-02-03
Abstract: (1) Vector that on introduction into a suitable bacterial host cell contg. the thermolabile repressor C (I) renders the host cell capable, when the temp. is raised to a level at which the repressor is inactivated, of effecting expression of a desired gene inserted in the vector to produce polypeptide (I) encoded by the gene is new when it comprises a double-stranded DNA molecule including in 5'- to 3'- order. (a) DNA sequence contg. the promoter and operator P(L)O(L) from lambda bacteriophage; (b) a N utilisation site for binding antiterminator N protein; (c) a first restriction enzyme site permitting replacement of the DNA sequence contg. the ribosomal binding site following after; (d) DNA sequence contg. a ribosomal binding site for making the MRNA of the desired gene capable of binding to ribosomes in the host cell; (e) ATG initiator codon or a DNA sequence converted into the codon on insertion of the desired gene into the vector; and (f) a second restriction enzyme site for inserting the desired gene into the vector in phase with the ATG initiation codon; and (g) a DNA sequence contg. an origin of replication from a bacterial plasmid capable of autonomous replication in the host cell; and for selection, DNA sequence contg. a gene associated with a selectable or identifiable phenotypic trait manifested when the vector is present in the host cell, or DNA sequence contg. fragment C (I) 434, including the gene for the C (I) 434 repressor protein and its associated promoter and operator sequence.
Patent DE-3687593-T2 (DE)
Inventor: BARGIGIA GIANANGELO
IPC: G01N25/00
Filed: 1986-04-17
Granted: 1993-07-15
Abstract: Perfluoropolyethers having an average molecular weight higher than 390 and respectively having a kinematic viscosity lower than 8.5 cSt (at 20°C), and such as to distill by not more than 10% at temperatures lower than 140 °C, and by at least 90% at temperatures not higher than 260°C, or, in the case in which the perfluoropolyether does not contain CF-(CF<sub>3</sub>)CF,O units, having a viscosity lower than 18 cSt (at 20°C), and such as to distill by not more than 10% at temperatures lower than 140 °C, and by at least 90% at temperatures not higher than 280°C, are used as the only high-temperature and low- temperature working fluid in the Thermal Shock Tests to which the electronic components are submitted, and at the same time are advantageously used in other tests used in the electronic industry, such as the Gross Leak Test and the Burn in Test, allowing the operators in this field to use one single fluid for a whole set of uses.
Patent DE-3786635-T2 (DE)
Inventor: WHITE WILLIAM COMFORT
IPC: A62B18/02
Filed: 1987-10-13
Granted: 1994-02-24
Abstract: A face mask (2) for a respirator is equipped with multiple seals (12, 18) on a lip (10) which turns inward at the periphery of the face mask (2). The seals (12, 18) include at least one fin which extends from the surface of the lip for contact with the face. The respirator has a port (6) for exhalation valve near the nose of the wearer and has pleats (4) for expansion of the mask (2) between the exhalation port (6) and the chin. Inhalation ports (8) are located at the sides of the respirator near the cheeks.
Patent DE-3852555-T2 (DE)
Inventor: JOHNSON GRAHAM
IPC: A61K31/425
Filed: 1988-03-15
Granted: 1995-05-04
Abstract: Use of a compound of the general formula I <CHEM> or of a pharmaceutically acceptable salt thereof wherein R<1> and R<2> are the same or different and are hydrogen  straight or branched alkyl of from one to six carbon atoms,  lower alkylaryl,  lower alkenyl,  phenyl,  CF3,  hydroxy,  lower alkoxy,  lower alkylthio,  lower alkylsulphonyl,  CF3O at the six position,  halogen,  nitro,  carboxy,  lower alkoxycarbonyl,  NR<5>R<6>CO,  NR<5>R<6>  R<5>CONR<5>,  CN,  NR<5>R<6>SO2, wherein R<5> and R<6> may be the same or different and are hydrogen, lower alkyl or aryl; R<1> and R<2> may together form a carbocyclic or methylenedioxy ring;  R<3> is hydrogen;  R<4> is hydrogen,  lower alkyl, lower alkyl substituted by a substituted or unsubstituted heterocyclic group,  methylcycloalkyl,  benzyl,  phenethyl,  phenyl,  substituted phenyl,  alkyl,  propargyl, with the proviso that R<1>, R<2>, and R<3> must be hydrogen when R<4> is not hydrogen, for the preparation of a pharmaceutical for treating cerebrovascular disorders.
Patent DE-3875721-T2 (DE)
Inventor: TSAU HENG-KO
IPC: A23L27/30
Filed: 1988-07-14
Granted: 1993-04-01
Abstract: A method for the production of a self stabilized composition of dipeptide sweeteners useful in cooking and baking applications yields dipeptide granules of substantially uniform spherical shape that fall within a narrow particle size distribution range. The granules produced thereby possess both heat stability and a sustained release mechanism that insures proper and uniform dissolution and dispersion within the baked product. The heat stability is then further enhanced by a pH buffer or weak acid in the granule or by encapsulating said granule with fat, protein, starch or other polymers.
Patent DE-3883100-T2 (DE)
Inventor: GOSSET SERGE
IPC: C23C22/23
Filed: 1988-06-24
Granted: 1994-03-10
Abstract: Mixed phosphatation acid solution suitable for resulting on a metal substrate in the simultaneous deposition of at least two metal ions, at least one of which is generally chosen from the group comprising zinc, manganese and iron, the said solution being characterised in that it includes
 - a polyphosphate of formula (XPO3)n in which n >/= 3 and X denotes an alkali or alkaline-earth metal or ammonium, and
 - a chelating agent.
Patent TR-199800230-T2 (TR)
Inventor: MRUSEK KLAUS
IPC: A01N53/06
Filed: 1996-08-05
Abstract: Mevcut bulus salt transflutrin bazli, aktif bilesim mikro-kapsüllenmis oldugu için uçan böceklere karsi üstün yer-yikici etki ve beyan edilen kaçirici etki gibi çok önemli özelliklere sahip ve eklem bacaklilar ile diger yürüyen böceklere karsi uzun-süre kalici etkisi olan yeni bir böcek öldürücü aktif bilesim ile ilgilidir.
Patent TR-199801140-T2 (TR)
Inventor: ALIG BERND
IPC: C07D277/26
Filed: 1996-12-10
Abstract: The invention relates to novel substituted thiazolines of the formula (I)in whichAr1 and Ar2 each represent independently of one another optionally substituted phenyl,processes for their preparation, and their use for controlling animal pests.
Patent DE-60007495-T2 (DE)
Inventor: BILLINGS ALAN L
IPC: D03D15/00
Filed: 2000-10-19
Granted: 2004-12-02
Abstract: An unlaminated belt (40) for a single-facer section (10) of a corrugated board production line has a single base structure (52) in the form of an endless loop lacking a seam. The base structure (52) is made up of yarns (56, 54) oriented in the machine, or running, and cross-machine directions of the belt (40). At least one layer of staple fiber material (60) is needled into the outside (58) of the base structure (52), extends at least partly therethrough, and forms a layer (64) on the outside (58) of the base structure. The base structure (52), once so needled, is impregnated with a polymeric resin material (66). The yarns (56, 54) of the base structure, the staple fiber material (60) and the polymeric resin material (66) are all of high-temperature-resistant materials to enable the belt (40) to withstand the conditions under which it must operate on a corrugator machine. <IMAGE>
Patent DE-60010857-T2 (DE)
Inventor: HAMMER PER
IPC: E04F15/20
Filed: 2000-01-13
Granted: 2004-11-04
Abstract: The present invention relates to a flooring structure in which the beams (1, 8) of the flooring structure are not interconnected with one another apart from in certain discrete points, for example in bearing supports. In this instance, the bearing beams (1, 8) of the flooring structure do not dynamically co-operate with one another in any significant manner. As a result, improved footstep sound insulation will be obtained since the flooring structure only reacts locally to a dynamic loading. The flooring structure emits only sound in an area close to the applied dynamic loading. In the flooring structure according to the present invention, the beams (1, 8) lie considerably closer to one another compared with that which has previously been normal for light wooden flooring structures. In one embodiment of the present invention, the beams (8) and/or studs (10) placed between the beams (1, 8) and floor panels (5) are provided with grooves (9). As a result of these grooves (9) torsional and compression rigidity at the anchorage points with the floor are reduced, which gives improved footstep sound insulation compared with beams and/or studs without grooves.
Patent DE-60010867-T2 (DE)
Inventor: BARNHART MICHAEL
IPC: C07C37/58
Filed: 2000-01-31
Granted: 2006-09-07
Abstract: A method and composition are disclosed for the oxidation of aromatic substrates in the presence of oxygen, a catalyst, a proton source, and a non-gaseous reductant. In a preferred embodiment, benzene is oxidized to phenol in the presence of oxygen, a vanadyl catalyst, trifluoroacetic acid as a proton source, and ferrocene as a reductant. The method is economical, safe, and amenable to commercial scale-up.
Patent DE-60012485-T2 (DE)
Inventor: RAYMOND KENNETH N
IPC: C07F5/00
Filed: 2000-02-18
Granted: 2005-08-18
Abstract: The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one salicylamidyl moiety. Also provided are probes incorporating the salicylamidyl ligands of the invention and methods utilizing the ligands of the invention and probes comprising the ligands of the invention.
Patent DE-60019509-T2 (DE)
Inventor: NAKAZATO HIROSHI
IPC: G03G15/00
Filed: 2000-07-19
Granted: 2005-10-13
Abstract: A development bias calculation and an electrifying bias calculation are executed in this order. In the development bias calculation, a plurality of toner images are formed as first patch images (PI1) while changing the development bias. An optimal development bias, which is necessary to obtain the target density, is determined based on densities of the first patch images (PI1). In the electrifying bias calculation, toner images are formed as second patch images (PI2) while changing the electrifying bias with the development bias fixed to the optimal development bias. An optimal electrifying bias, which is necessary to obtain the target density, is determined based on densities of the second patch images (PI2).  <IMAGE>
Patent DE-60024968-T2 (DE)
Inventor: KASEVICH S
IPC: A61B18/18
Filed: 2000-02-08
Granted: 2006-09-07
Abstract: Medical systems and instruments which utilize microwave energy to provide heat treatment and diagnostic imaging of tissue are provided. One medical treatment system for treating tissue includes an antenna having a radiating element configured to transmit electromagnetic energy toward a desired area of the tissue and having an interior volume for receiving a heat exchange fluid, thereby changing the temperature proximal to the desired area of the tissue.
Patent DE-60025520-T2 (DE)
Inventor: ALA-LUUKKO SAMI
IPC: H04L29/12
Filed: 2000-11-06
Granted: 2006-09-14
Abstract: A method and a system for transmitting messages containing multimedia information or content that enables transmission and communication of multimedia messages between subscribers connected to telecommunication systems of different system operators. The inventive system includes a first mobile station terminal from which a multimedia message is sent, a second mobile station terminal that is the intended recipient of the multimedia message, a digital mobile network, a first multimedia message server for receiving a multimedia message from the first mobile station terminal, a first address database associated with the first multimedia message server, a second multimedia message server for receiving the multimedia message from the first multimedia message server, an IP network for carrying communications between the first and second multimedia message servers, and a second address database associated with the second multimedia message server.
Patent DE-60027516-T2 (DE)
Inventor: NAKAJIMA YASUMASA
IPC: H04N5/225
Filed: 2000-09-06
Granted: 2006-09-28
Abstract: In step S101, an electrical signal output from an CCD is converted into a digital signal. In step S103, digital data output from an analog-to-digital converter are recorded in RAM. In step S104, the data recorded on RAM are subjected to various image correction. In steps S105 through S110, the data corrected in step S104 are compressed in accordance with a JPEG compression scheme. In step S106, there is determined a location in which characteristic data are to be embedded. In step S107, characteristic data are produced from image data. In step S108, encrypted data are formed by means of encrypting characteristic data. In step 5109, encrypted characteristic data are embedded into image data.  <IMAGE>
Patent DE-60029187-T2 (DE)
Inventor: SHOTTON GILBERT
IPC: E02D17/13
Filed: 2000-06-29
Granted: 2007-05-31
Abstract: The present invention relates to cell and animal models for a disease condition and in particular to an animal model which can function as a model for neurodegenerative diseases, such as Alzheimers.
Patent DE-60029299-T2 (DE)
Inventor: GONZALES EDGAR A
IPC: C08L23/02
Filed: 2000-02-28
Granted: 2007-07-19
Abstract: Improved thermoplastic compositions comprising a blend of ground vulcanized rubber and olefin polymer which have improved compatibility and mechanical properties are described; they are improved by incorporation of an alpha olefin copolymer.
Patent DE-60030457-T2 (DE)
Inventor: ANDERSON JOHN
IPC: G16H70/60
Filed: 2000-09-22
Granted: 2007-02-01
Abstract: There is provided a system for the delivery of medicament comprising a medicament container; a dispensing mechanism for dispensing medicament from the medicament container; an electronic data management system; and a communicator for wireless communication with a network computer system to enable communication of data between the network computer system and the electronic data management system. The electronic data management system comprises a memory for storage of data; a microprocessor for performing operations on the data; and a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data.
Patent DE-60038051-T2 (DE)
Inventor: SILVERBROOK KIA
IPC: B41J2/235
Filed: 2000-12-07
Granted: 2009-02-05
Abstract: A printhead is provided having an assembly of printhead modules. Each printhead module has a support defining fluid chambers, a fluid distributor on the support, and an integrated circuit on the distributor so that fluid in the chambers is distributed to the fluid ejection nozzles of the integrated circuit by the distributor. The support and distributor of each printhead module are shaped to define complementary formations on opposite sides of that printhead module so that the printhead modules are mated together in an angled fashion with the integrated circuits of the mated printhead modules abutting together and diagonally overlapping to define at least one row of fluid ejection nozzles of the printhead.
Patent DE-60100517-T2 (DE)
Inventor: MILNER DAVID V
IPC: F17C13/02
Filed: 2001-03-13
Granted: 2004-06-03
Abstract: An apparatus and method provide automatic regulation of flow of fluid from a source (11) where it is stored as liquified gas. The apparatus includes a flow control valve (31) connected in a conduit (21) connecting the source (11) in flow communication to a vaporizer (19). The apparatus also includes a valve controller (71) operable to regulate the flow of fluid in liquid phase at least partially through the valve (31). The controller (71) derives the energy to operate the valve (31) and the controller (71) from the fluid when the fluid is in its gas phase. The vaporizer (19) can be used to warm the fluid passing therethrough. <IMAGE>
Patent DE-60101079-T2 (DE)
Inventor: KAWAMURA KOICHI
IPC: B41M5/36
Filed: 2001-12-13
Granted: 2004-07-15
Abstract: A lithographic printing plate precursor comprising a support having a hydrophilic surface containing hydrophilic graft polymer chains and a heat-sensitive layer containing at least either of fine particulate polymer and microcapsules, which is excellent in on press developing property, sensitivity and printing durability.
Patent DE-60105835-T2 (DE)
Inventor: BOESVELD MARCO
IPC: C07C7/00
Filed: 2001-10-05
Granted: 2005-02-10
Abstract: A process for the production of triptane, said process comprising: isomerising a hydrocarbon feedstock by containing said feedstock with an isomerisation catalyst at a reaction temperature of -50 to 25° C., and a contact time of 0.01 to 150 hours, such that the triptane selectivety of the isomerisation reaction is at least 5% as a proportion of said hydrocarbon feedstock.
Patent DE-60108651-T2 (DE)
Inventor: JEONG MOON
IPC: A61K38/095
Filed: 2001-09-27
Granted: 2006-03-30
Abstract: Disclosed is a thermogelling biodegradable aqueous polymer solution useful in providing a bioactive agent delivery system. The present invention provides a thermogelling biodegradable aqueous polymer solution with a polyethylene glycol (PEG) block and a biodegradable polyester block, where the blocks are linked to form a polymer of a general structure comprising the formula of An(B), where n is greater than 2 and A is selected from the group consisting of a polyethylene glycol block and a biodegradable polyester block, B is selected from the group consisting of a polyethylene glycol block and a biodegradable polyester block, and A is different from B.
Patent DE-60109893-T2 (DE)
Inventor: TANAKA YOSHINORI
IPC: B26D1/40
Filed: 2001-01-12
Granted: 2005-11-10
Abstract: There is disclosed a cut line forming method including: using a cutter roll (1) having cutting blades (2) protruded on its outer circumference and an anvil roll (10) for receiving the cutting blades; feeding a sheet (20) into the clearance between the cutter roll and the anvil roll; and turning the rolls individually to form cut lines (21) in the sheet. The cutting blades (2) of the cutter roll (10) are formed into a shape of letter "V". The anvil roll has receiving faces (11) of a predetermined width (w) formed at an interval in a roll axis direction. The cutter roll (1) is turned to direct the crests of the V-shape of the cutting blades forward of the turning direction thereby to advance cuts from the side of the crests of the V-shape so that cut lines corresponding to the width size of the receiving faces may be intermittently formed in the sheet along the V-shape.
Patent DE-60112598-T2 (DE)
Inventor: CHEN JIANHUA
IPC: A61F2/06
Filed: 2001-06-08
Granted: 2006-04-06
Abstract: The present invention relates to a catheter device having a dilatation balloon formed from a polymeric material crosslinked by moisture through —Si—O—Si— linkages, and to a method of making the same. The polymeric material is formed by reacting at least one organofunctional hydrolyzable silane with at least one polymer. The crosslinked polymeric structure is ideal for forming more resilient and durable catheter balloons. In particular, the catheter balloons have excellent abrasion resistance.
Patent DE-60115668-T2 (DE)
Inventor: BINDER YEHUDA
IPC: H04L25/00
Filed: 2001-09-12
Granted: 2006-09-07
Abstract: A communication system (50) for concurrently carrying multiple distinct signals over multiple transmission-line segments, each having at least two conductors, comprises a first (15a, 15b) transmission-line segment carrying a first signal and a second (15c, 15d) transmission-line segment carrying a second signal distinct from the first signal. The first and second transmission-line segments are connected to each other at a single connection point (51a, 51b) to which a termination device (30) is connected. The termination device is operative to stop the first signal to pass to the second transmission-line segment, and to stop the second signal to pass to the first transmission-line segment.
Patent DE-60121040-T2 (DE)
Inventor: ROSNELL MARKKU
IPC: A63C11/24
Filed: 2001-12-17
Granted: 2006-11-30
Abstract: A pushing stick and a ring for the same. The lower end of a shaft comprises a stick ring comprising a fastening part and a projection-like ring frame attached to the fastening part. The bar-like ring frame is directed forwards with respect to the direction of travel and its front is provided with at least one spike. Said spike then resides at a distance from the central axis of the shaft, whereby a bending moment is directed to the ring frame on account of the push force. The ring frame is rigid in order to be able to transmit the bending moment being formed to the lower end of the shaft.
Patent DE-60122580-T2 (DE)
Inventor: CRAIG ANDREW SIMON
IPC: A61K31/44
Filed: 2001-12-21
Granted: 2007-08-30
Abstract: Disclosed are 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione mesylate salts, or solvates thereof; processes for preparing such compounds, compositions comprising such compounds and the use of such compounds in medicine.