baber/WOPTO huggingface dataset:
Patent GB-8621864-D0 (GB)
Title: Chemical process
IPC: C07D213/68
Filed: 1986-09-11
Abstract: A process for preparing 3-[4-(4-oxo-1,4-dihydropyridin-1-yl)benzoyl]butanoic acid is described which comprises reacting 3-(4-fluorobenzoyl)butanoic acid with 4-hydroxypyridine characterised in that the process is performed under aqueous conditions in the presence of a suitable base.
Patent GB-8728018-D0 (GB)
Title: Antifolate agents
IPC: C07D239/48
Filed: 1987-11-30
Abstract: 2,4-Diamino-5-phenylpyrimidines in the form of the free base or an acid addition salt thereof are provided having the structural formula (I):   <IMAGE> I  wherein R1 is an alkoxy, aralkoxy or a mono-substituted or disubstituted amino group, R2 is a nitro group, and R3 is an alkyl group. The compounds act as antifolate agents and are useful for therapeutic treatment, for example as antitumour agents, antipsoriatic agents, antibacterial agents, antitrypanosomal agents and antimalarial agents. Pharmaceutical preparations comprising these compounds for administration to mammals, and methods for preparing the compounds, are disclosed. Particularly useful new compounds, especially for antitumour therapy, have the structural formula IA:   <IMAGE> IA   in which formula IA: n is 1-6; R1 represents hydrogen or alkyl; R4, R5 and R6, which may be identical or different, each represnt hydrogen, alkyl, alkoxy, halo, nitro, perfluoroalkyl, a group of formula -CO2Ra wherein Ra represents hydrogen, alkyl or alkoxyalkyl, or a group of formula -COBRbRc wherein Rb and Rc which may be identical or different each represent alkyl; and R3 represents alkyl.
Patent GB-8805328-D0 (GB)
Title: Data processing system with pluggable option cards
IPC: G06F12/06
Filed: 1988-03-07
Abstract: A data processing system includes a central processing unit (CPU), a main memory unit, and input/output (I/O) sockets, each adapted to receive a selected one of a plurality of different and/or similar option cards. Each card contains (or is connected to) and controls a respective peripheral device, and each card is pre-wired with an ID value corresponding to its card type. Programmable option registers on each card store parameters such as address information, priority levels, and other system resource parameters. A setup routine, during initial power-on, retrieves and stores the appropriate parameters in the I/O cards and also in socket locations in main memory, one location being assigned to each input/output socket. Each socket location is adapted to hold the parameters associated with the card inserted in its respective socket and the card ID value. That portion of main memory containing the socket locations is adapted to maintain the parameter and ID information by means of battery power when system power fails or is disconnected, i.e., a non-volatile memory portion. Subsequent power-on routines are simplified by merely transferring parameters from the memory to the card registers if the status of all the sockets has not changed since the last power-down.
Patent GB-8817222-D0 (GB)
Title: Thermal transfer printing
IPC: B41M5/388
Filed: 1988-07-20
Abstract: A thermal transfer printing sheet, suitable for use in a thermal transfer printing process, comprising a substrate having a coating comprising a water-insoluble dye of the formula: <CHEM>  wherein  R represents the residue of an active methylene compound; X represents hydrogen, halogen or an optionally substituted alkyl, aryl or heteroaryl radical; Y represents cyano, nitro, alkanoyl, aroyl, alklsulphonyl, arylsulphonyl or a group of the formula -COOR<1> or -CONR<2>R<3> wherein R<1> represents a hydrocarbyl radical and each of R<2> and R<3>, independently, represents hydrogen or a hydrocarbyl radical; and E represents the residue of a coupling component.
Patent GB-8829088-D0 (GB)
Title: Compounds
IPC: C07C67/03
Filed: 1988-12-13
Abstract: Polymers of structure: <CHEM> in which X is a cross-linking unit, X<1> is a comonomer unit, R<1> is hydrogen or C1-4alkyl and R<1> and R<2> are the same or different and are each C1-2alkyl or aralkyl, or R<1> to R<3> together form a ring, compositions containing them and their use in therapy for the lowering of serum cholesterol levels.
Patent GB-9102891-D0 (GB)
Title: Cementitious composition
IPC: B28B23/02
Filed: 1991-02-12
Abstract: A cementitious composition containing metal-coated fibres especially metal-coated carbon fibres in an amount of 0.1 up to 5% by weight relative to the weight of the cement component of the composition. The composition can be used as a conductive layer in a cathodically protected reinforced concrete.
Patent GB-9311892-D0 (GB)
Title: Device
IPC: A61M15/00
Filed: 1993-06-09
Abstract: PCT No. PCT/EP94/01859 Sec. 371 Date Jun. 19, 1996 Sec. 102(e) Date Jun. 19, 1996 PCT Filed Jun. 9, 1993 PCT Pub. No. WO94/28956 PCT Pub. Date Dec. 22, 1994The present invention relates to a device for administering pharmaceutical substances by spraying the contents of a container formed of plastics material. The device comprises a pair of members between which is supported the container, the members being movable relative to each other between a first position in which the container is not compressed sufficiently to burst it and a second position in which the members are capable of exerting sufficient pressure on the container to burst it and expel the contents through a discharge outlet.
Patent GB-9324752-D0 (GB)
Title: Process
IPC: C07C27/02
Filed: 1993-12-02
Abstract: The continuous prodn. of 1,4-cyclohexanedimethanol having a predetermined trans:cis isomer ratio comprises (a) providing a hydrogenation zone contg. a charge of granular hydrogeneration catalyst selected from Cu-contg. catalysts and Gp. VIII metal-contg. catalysts capable of catalysing the hydrogenation of esters; (b) determining a Reference Activity (RA) of the catalyst by measuring the extent of conversion of the dialkyl 1,4-cyclohexanedicarboxylate to 1,4-cyclohexanedimethanol in the passage of a reaction mixt. comprising the dialkyl 1,4-cyclohexanedicarboxylate and a H2-contg. gas through the catalyst at a preselected feed temp., feed pressure, dialkyl 1,4-cyclohexanedicarboxylate feed rate, and H2-contg. gas:dialkyl 1,4-cyclohexanedicarboxylate molar ratio; (c) determining fan Effective Residence Time (ERT) for contact of the reaction mixt. at the preselected feed temp. and feed pressure with the catalyst at the RA which produced 1,4-cyclohexanedimethanol having he desired trans:cis isomer ratio; (d) forming a vaporous feed stream comprising the dialkyl 1,4-cyclohexanedicarboxylate and a H2-contg. gas having a preselected molar ratio; (e) feeding the vaporous feed stream to the hydrogenation zone at a constant temp. of 150-350 deg. C and which is above the dew point of the feed stream and at a constant pressure of 150-2000 psia at a rate which corresponds to an Actual Residence Time (ART) of the feed stream in contact with the catalyst which yields 1,4-cyclohexanedimethanol of the desired trans:cis isomer ratio; (f) recovering a prod. stream contg. 1,4-cyclohexanedimethanol; (g) monitoring the Actual Activity (AA) of the catalyst with passage of time by measuring the extent of conversion of the dialkyl 1,4-cyclohexanedicarboxylate to 1,4-cyclohexanedimethanol under actual operating conditions of feed temp., feed pressure, dialkyl 1,4-cyclohexanedicarboxylate feed rate, and H2-contg. gas:dialkyl 1,4-cyclohexanedicarboxylate molar ratio; and (h) adjusting at least one feed condition of the vaporous feed stream to the hydrogenation zone selected from (1) the dialkyl 1,4-cyclohexanedicarboxylate feed rate, and (2) the H2-contg. gas: dialkyl 1,4-cyclohexanedicarboxylate molar ratio; while maintaining the feed stream above its dew point to provide an ART which corresponds to the ERT required to provide 1,4-cyclohexanedimethanol having the desired trans:cis ratio in accordance with the relationship (I). The dialkyl cyclohexanedicarboxylate is selected from di(1-4C alkyl) cyclohexanedicarboxylates.
Patent GB-9402169-D0 (GB)
Title: Process of making paper
IPC: D21H21/10
Filed: 1994-02-04
Abstract: PCT No. PCT/GB95/00231 Sec. 371 Date Oct. 4, 1995 Sec. 102(e) Date Oct. 4, 1995 PCT Filed Feb. 6, 1995 PCT Pub. No. WO95/21295 PCT Pub. Date Aug. 10, 1995During the manufacture of paper from a cellulosic suspension, retention is improved by adding to the suspension a water soluble cationic polymer containing 0.1 to 15 mole % cationic monomer groups and having an intrinsic viscosity of at least 4 dl/g and then adding a substantially water soluble formaldehyde condensate resin. This resin is preferably a phenol sulphone formaldehyde resin. Preferred phenol sulphone formaldehyde resins are materials wherein at last 70 mole % of the recurring groups are dihydroxyl phenyl sulphone groups free of sulphonic acid groups.
Patent GB-9408725-D0 (GB)
Title: Production of aqueous polymer compositions
IPC: C09D151/00
Filed: 1994-05-03
Abstract: PCT No. PCT/IB95/00331 Sec. 371 Date Nov. 1, 1996 Sec. 102(e) Date Nov. 1, 1996 PCT Filed Apr. 27, 1995 PCT Pub. No. WO95/29963 PCT Pub. Date Nov. 9, 1995Process for making organic solvent-free aqueous crosslinkable polymer composition comprising: a) preparing an aqueous solution of an acid-functional oligomer with Tg 10 to 125 DEG  C. and having crosslinker functional groups; b) conducting an aqueous emulsion polymerization to make an aqueous emulsion of an olefinic hydrophobic polymer in the presence of the aqueous oligomer solution, the hydrophobic polymer having Tg at least 25 DEG  C. below that of the oligomer and optionally crosslinker functional groups, and c) combining with a crosslinking agent reactable with the crosslinker groups of the oligomer and polymer, said composition having Koenig hardness of >/=40 sec and minimum film forming temperature (MFFT) </=55 DEG  C. Also the aqueous composition so formed and its use in various applications. The aqueous composition has excellent properties and in particular an advantageous balance of MFFT and Koenig hardness.
Patent GB-9418443-D0 (GB)
Title: Therapeutic agents
IPC: A61K31/495
Filed: 1994-09-13
Abstract: PCT No. PCT/EP95/03483 Sec. 371 Date Mar. 12, 1997 Sec. 102(e) Date Mar. 12, 1997 PCT Filed Sep. 1, 1995 PCT Pub. No. WO96/08485 PCT Pub. Date Mar. 21, 1996Compounds of formula (I):    <IMAGE>  (I)  and their pharmaceutically acceptable salts, wherein R1 and R2 are each independently Cl, Br, CH3, CH2CH3 or CF3; R3 is H, CH3 or CH2CH3; and X is a 5-membered heterocyclic group containing up to four nitrogen atoms, attached via a nitrogen atom, the said group being optionally substituted by C1-C6 alkyl or (CH2)nNR4R5, wherein n is an integer from 1 to 5 and R4 and R5 are each independently H, C1-C6 alkyl, C3-C6 cycloalkyl or C1-C4 alkyl substituted by phenyl or pyridyl, or R4 and R5 are linked to form, together with the nitrogen atom to which attached, a pyrrolidine, piperidine, piperazine, N-(C1-C4 alkyl) piperazine, morpholine or azepine group, or, when X is triazolyl, said group may optionally be benzofused, are NMDA antagonists of value in the treatment of acute neurodegenerative disorders, e.g. arising from stroke or traumatic head injury and in chronic neurological disorders, e.g. senile dementia and Alzheimer's disease.
Patent GB-9509115-D0 (GB)
Title: Improvements in or relating to reinforced concrete structural elements
IPC: E04C5/06
Filed: 1995-05-04
Abstract: A shear failure reinforcing system for structural elements, in which thin elongate strips of high stiffness material are anchored around a layer of conventional reinforcement, and/or are anchored around a plurality of layers of conventional reinforcement, such that the strips tie the element and improve its resistance to shear failure.
Patent GB-9511679-D0 (GB)
Title: Novel process
IPC: C12P17/18
Filed: 1995-06-09
Abstract: A process for increasing the amount of clavam produced by an organism having both a clavam pathway or a portion thereof and a cephalosporin pathway or a portion thereof by interfering with the conversion of L-lysine to L-alpha-aminoadipic acid in the cephalosporin pathway. Plasmids containing a defective LAT (lysine amino transferase) gene and organisms containing such plasmids are also provided.
Patent GB-9901485-D0 (GB)
Title: Improvements in or relating to powdered coating compositions
IPC: C09D163/00
Filed: 1999-01-22
Abstract: A powdered coating composition comprises a thermosetting resin which consists of two components. The first component includes an acid reactive material comprising a polyepoxide or beta-hydroxyalkylamide compound. The second component is an acid terminated resin which reacts with the first component. A curing agent including a polycarboxylic acid having a functionality of at least 3 and a source of tertiary or quanternary nitrogen is present to react with an excess of the first component, thereby curing thermosetting resin.
Patent GB-9908868-D0 (GB)
Title: Locking mechanism
IPC: E05B63/16
Filed: 1999-04-20
Abstract: A locking mechanism comprises a casing (10) in which two followers (13, 30) are mounted for angular movement, the followers being directly connected to a common sliding drive link (58) by respective links (22, 36), with lost motion between each follower and its associated link. A latchbolt (46, 49) is biased to extend from the casing, being retractable by an actuator (41) operated by movement of one of the followers (13), whilst a hookbolt (22) constituting one of the links is moved into or out of the casing by movement of that one of the followers. The drive link is slidable to an operative position, where it can actuate upper and lower secondary locking members, and in the operative position the hookbolt is extended from the casing. The drive link can be locked against release from the operative position by actuation of a key operated cylinder lock, such locking also retaining the hookbolt in its extended position.
Patent GB-9913819-D0 (GB)
Title: Assay
IPC: G01N33/53
Filed: 1999-06-14
Abstract: The present invention provides a method of determining the presence or amount of newly synthesised antibody in a sample in response to an immunogen by detecting the released antibodies or parts thereof in a sample containing lymphocytes which have been disrupted whereby to release the synthesised antibodies or parts thereof associated with said lymphocytes whereby to determine the presence or amount of newly synthesised antibody in said sample, methods of diagnosis using said method and kits for performing the method. The method may also be modified to allow detection of non-specific infection indicators.
Patent GB-9915558-D0 (GB)
Title: Process for the production of glycerol dinitrates
IPC: C07D303/16
Filed: 1999-07-03
Abstract: A method for preparing either the 1,2-dinitrate or the 1,3-dinitrate of glycerol involves protecting glycidol respectively with either a trialkylsilyl ether group or an acetate group then nitrating with dinitrogen pentoxide under anhydrous conditions, after which the protecting group is removed. High yields of exclusively the desired isomer are obtained avoiding the difficulties of isomer separation which arise with conventional methods.
Patent HU-9301971-D0 (HU)
Title: Shaving compositions
IPC: A61K8/00
Filed: 1992-01-14
Abstract: Shaving prod. is in the form of a self-foaming gel comprising water, a water-soluble soap, a volatile self-foaming agent, 0.0005-0.5 wt.% of a fluorosurfactant and a hydrogenated polyisobutene. More specifically, the prod. pref. comprises 0.5-5 wt.% hydrogenated polyisobutene and 0.001-0.1 wt.%, more pref. 0.002-0.01 wt.%, fluorosurfactant. Pref. prod. compsn. comprises 65-80 wt.% water; 12-25 wt.% water-soluble soap; 1-5 wt.% volatile self-foaming agent; 0.002-0.01 wt.% fluorosurfactant; 1-4 wt.% hydrogenated polyisobutene; and further 0.1-2 wt.% water-soluble polymer.
Patent HU-9302344-D0 (HU)
Title: Apoli protein-variant dimers and method for producing them
Inventor: CIRTORI CESARE
IPC: C12P21/04
Filed: 1992-12-11
Abstract: PCT No. PCT/SE92/00858 Sec. 371 Date Nov. 4, 1993 Sec. 102(e) Date Nov. 4, 1993 PCT Filed Dec. 11, 1992 PCT Pub. No. WO93/12143 PCT Pub. Date Jun. 24, 1993Substantially pure dimers of Apolipoprotein Al-Milano (Al-M/APO Al-M) isolated and characterized from plasma are provided. Pharmaceutical compositions comprising the Apo Al-M/Apo Al-M are also provided. Apolipoprotein Al-M dimer can be produced in a recombinant Escherichia coli system or collected from plasma from Apolipoprotein Al-Milano carriers. Atherosclerosis and cardiovascular diseases can be treated with the dimer. Medicaments containing the dimer can also be used for preventing thrombosis in different clinical circumstances, both at the arterial and at the venous level. The dimer can also act as a prodrug for the monomer.
Patent HU-9302972-D0 (HU)
Title: Process for producing of 4-acyl-2-alkyl-6-terc. butyl-phenols
Inventor: GIBSON THOMAS WILLIAM
IPC: C07C45/79
Filed: 1992-01-31
Abstract: The subject invention relates to a process for the preparation of 2-alkyl-4-acyl-6-tert-butylphenol compound having the chemical structure:    <IMAGE>  (1)  wherein -R is an aliphatic group having a terminally unsaturated moiety selected from -C 3BOND CH and -CH=C=CH2, and R' is selected from saturated, straight, branched or cyclic alkyl having from 1 to about 10 carbon atoms; the 2-alkyl-4-acyl-6-tert-butylphenol compound being produced in a reaction mixture comprising the corresponding 2-alkyl-6-tert-butylphenol:   <IMAGE>  the corresponding carboxylic acid: RCOOH, and trifluoroacetic anhydride.
Patent HU-9400084-D0 (HU)
Title: Water-soluble addition polymers of cyclohexene anhydrides
Inventor: SWIFT GRAHAM
IPC: C08F222/04
Filed: 1994-01-12
Abstract: The present invention provides water-soluble polymers containing, as polymerized units: (a) from about 3 to about 95 percent by weight of one or more cyclohexene anhydrides or the alkali metal or ammonium salts thereof. The present further provides aqueous polymerization processes for making the polymers. The water-soluble polymers are useful as water-treatment additives for boiler waters and cooling towers and as detergent additives acting as builders, anti-filming agents, dispersants, sequestering agents and encrustation inhibitors.
Patent HU-9500494-D0 (HU)
Title: Trifluoromethylpyrroloindole carboxylic ester derivative and process for producing the same
Inventor: TERASHIMA SHIRO
IPC: A61P31/04
Filed: 1993-08-19
Abstract: Trifluoromethylpyrroloindole carboxylic ester derivatives represented by general formulae (1) and (2) having an antitumor activity, optically active isomers thereof, and pharmacologically acceptable salts thereof, wherein R represents lower alkyl; R<1> represents an alpha -amino acid residue, etc.; R<2> represents hydrogen, a hydroxyl-protecting group, etc.; and Y represents halogen, arylsulfonyloxy, etc. <CHEM>
Patent HU-9502268-D0 (HU)
Title: Sealing cover for an opening of a container
Inventor: WIENING HENZ-RUDOLF
IPC: B65B41/04
Filed: 1994-03-14
Abstract: PCT No. PCT/EP94/00777 Sec. 371 Date Sep. 8, 1995 Sec. 102(e) Date Sep. 8, 1995 PCT Filed Mar. 14, 1994 PCT Pub. No. WO94/21524 PCT Pub. Date Sep. 29, 1994A sealing cover for an opening of a container has a first foil that seals the opening of the container. A metallic foil, especially aluminum foil, is also provided for inductive sealing of the first foil at the lip of the opening, along with a removable sealing lid that is releasably screwed onto the container. A releasable adhesive control layer positioned between the first foil and the metallic foil, enables the metallic foil to be detached from the first foil after the sealing lid has been removed. An elastic layer is provided between the sealing lid and the metallic foil. Between the metallic foil and the elastic layer is a separation layer, which becomes liquid at induction temperatures, and a suction layer. During the induction process, the latter absorbs the liquified substance of the separation layer. The adhesive control layer does not have such an adjoining suction layer.
Patent HU-9601751-D0 (HU)
Title: Thiopirane derivatives
Inventor: INOMATA NORIO
IPC: C07D335/06
Filed: 1996-06-24
Abstract: A thiopyran derivative represented by the following formula (I) or (I'), or the salt thereof. <CHEM> wherein A is S or -CH=CH-; the dotted line indicates that the bond may be either present or absent; Z and Z' are typically <CHEM> L is an ethylene or trimethylene group; Y is CH or N; n is 2; B is a carbonyl group; m is 0 or 1; D is a phenyl group; and E1 and E2 are hydrogen atoms. These compounds exhibit a strong serotonin-2 blocking action and highly safe. Some compounds also exhibit an  alpha 1-blocking action and therefore are useful as an antihypertensive agent with less side effects. Thus, the thiopyran derivatives are useful as drugs for the treatment of circulatory diseases in general such as hypertension, ischemic heart disease, cerebrovascular disturbance, and peripheral circulatory disturbance.
Patent IT-8522316-D0 (IT)
Inventor: BRIOSI ANTONELLO
IPC: A47B57/40
Filed: 1985-09-30
Abstract: This invention refers to betterments to composite sheet metal shelvings with a relatively limited thickness, fitted with up-rights and cross-members, betterments, that essentially are characterised by the said up-rights being structurally "T" -shaped and having numerous "teeth", made by cutting and without removing material on the shaped "wings" of the said "T", each one of the teeth has a side converging towards the upper horizontal face, being drawn and are spaced slightly and substantially parallel to the said wings, engaging on the teeth thereof, assisted by the said converging side and hooking thereto, " cavities" pre-arranged on the opposite ends of the cross-members, cavities that have slight projections uppermost that contrast both with the upper side of the respective inserted tooth, and side-ways, with the said shapes of the wings, the whole complex is designed so that the connections between the up-rights and the cross-members ensure perfect stability and high mechanical resistance of the said shelvings, as well as hiding the said connections.
Patent IT-8246842-D0 (IT)
Inventor: BIADIGO MARIO
IPC: B28B11/18
Filed: 1982-07-09
Abstract: An automatic machine for the fettling of the syphon of sanitary appliances, comprising a vertical flat structure (30, 32, 33, 36) of overall elastically deformable configuration, which tapers downwards in such a manner as to be able to be inserted into the syphons (77) of the articles (7) and is provided laterally with two fettling sectors (35) arranged to rub the walls of the syphons (77), and which is supported by an operating head (10, 11, 15, 17, 24, 22) arranged to subject it to vertical reciprocating rectilinear motion and to simultaneous stepwise rotary motion; the operating head (10, 11, 15, 17, 24, 22) is mounted on a vertical slider (3) for its positioning at the required level.
Patent IT-8948320-D0 (IT)
Inventor: IELPO NICOLA
IPC: A44C3/00
Filed: 1989-09-01
Abstract: A coin blank, particularly for minting of coins and the like, is formed by an external element (1) of metal or metal alloy having a central aperture, on the edge surface (4) of which are cut perimetrally a series of spaced grooves (5), and by an internal element (6), of metal or metal alloy different from the former, on the edge surface of which is formed a perimetral ridge (8,9), said external and internal elements being coupled inseparably during the minting operation through the plastic flow of the material from said perimetral ridge (8,9) into said grooves (5) in said external element (1) and through the firm fitting of the material from said ridge into the portions of the edge surface of said central aperture in said external element (6), provided between adjacent grooves (5).