baber/WOPTO huggingface dataset:
Patent DE-112019003677-B4 (DE)
Title: In vivo post-translational-verarbeitung von zielproteinen mit furin in pflanzen: design, expression und produktion von funktionalen aktiven menschlichen furine in der n. benthamiana-pflanze
Inventor: MAMMEDOV TARLAN
IPC: C12P21/00
Filed: 2019-02-27
Granted: 2022-09-22
Abstract: Verfahren für Herstellung von Furin zur Verarbeitung von Zielproteinen in Pflanzen in vivo durch Koexpression von menschlichem Furin, einem Proprotein-verarbeitenden Enzym dadurch gekennzeichnet, dass es folgende Schritte umfasst;• die operative Verknüpfung der ersten Nukleotidsequenz, die die in SEQ ID NO: 1 oder SEQ ID NO: 2 angegebene Sequenz umfasst, mit einem Promotor derart, dass das Furin-Polypeptid exprimiert wird, wenn der Promotor aktiviert wird, wobei sie eine erste Nukleinsäure, umfassend eine erste Nukleotidsequenz, die ein menschliches Furin in hochlöslicher und funktionell aktiver verkürzter Form codiert, ist,• die operative Verknüpfung der zweiten Nukleotidsequenz, die eine zweite Nukleotidsequenz, die das erwähnte Polypeptid codiert, umfasst, mit einem Promotor derart, dass die erste Nukleinsäuresequenz beim Aktivieren des Promotors ein Polypeptid exprimiert wird, das aus einem der Vitamin K-abhängigen Gerinnungsfaktoren, Faktor FIX, Faktor VII oder C-Protein, ausgewählt ist.• Ko-exprimieren der ersten Nukleinsäure und der zweiten Nukleinsäure in der eukaryotischen Zelle, insbesondere in der Nicotiana bethamiana Pflanzenzelle oder Hefezelle, um das mit Furin behandelte Polypeptid herzustellen.
Patent CZ-284134-B6 (CZ)
Inventor: COCKER ALAN JOSEPH
IPC: G01N27/28
Filed: 1993-03-24
Abstract: Sonda sestává z trubkovitého tělesa (4)  tvořeného trubicí (6), uzavřenou na jednom konci  separátní špičkou (8) vytvořenou ze  stabilizovaného oxidu zirkoničitého, která tvoří  pevný elektrolyt, jímž mohou procházet ionty  kyslíku, přičemž trubice (6) je ze žáruvzdorného  materiálu odlišného od oxidu zirkoničitého a  sonda dále sestává z první referenční elektrody  (16) připojené k vnitřnímu povrchu špičky (8) z  oxidu zirkoničitého, uzemnění upraveného ke  spojení se zemí mimo styk s roztaveným kovem a  měřicí sestavy (24) zapojené mezi první  referenční elektrodu (16) a uzemnění.ŕ
Patent CZ-286927-B6 (CZ)
Title: Substance detection, identification and/or quantification method
Inventor: SQUIRRELL DAVID JAMES
IPC: C12Q1/6825
Filed: 1992-09-16
Abstract: Detection, identification and/or quantification of a material such as plant or animal tissue, microorganisms or cell-free D/RNA comprises (i) providing an oligonucleotide (OG), complementary to all or part of an OG sequence (I) characteristic of the D/RNA of the material, immobilised on the surface of an envanescent wave detector appts. waveguide; (ii) exposing the immobilised OG to the sample or D/RNA for hybridisation; (iii) associating the immobilised OG or material with a fluorescent agent (FA), before, during or on completion of hybridisation, such that the agent binds to the hybridised prod. but not to unhybridised OG; and (iv) measuring the bound FA using the wave detector appts.. Also claimed are (a) an assay kit contg. an OG as above, an FA and reagents for immobilising the OG to the waveguide; (b) an evanescent wave detector biosensor comprising a temp.-controllable environment; and (c) a waveguide for use in (b) comprising immobilised OG.
Patent CZ-291642-B6 (CZ)
Title: Ash control valve apparatus
Inventor: SCHAKER YORAM
IPC: F23C10/28
Filed: 1996-08-19
Abstract: An ash control valve apparatus (22) for use in a system that includes a fluidized-bed (12) system is disclosed. The invented apparatus (22) includes a housing (24), a seat (32) in the housing (24) for passage of particulate material, a plug (30) dimensioned and configured for mating engagement with the seat (32), and apparatus for moving the plug (30) from a first position wherein the plug (30) is disposed in seated engagement with the seat (32) to a second position wherein the plug (30) is disposed in spaced relationship to the seat (32). The apparatus for moving the plug (30) includes apparatus for mounting the plug (30) that includes an elongated tube (34) to which the plug (39) is fixed. The apparatus for mounting the plug (30) includes a plurality of axially extending ribs (82) disposed on the circumference of the elongated tube (34) and a plurality of channels (84) disposed in a bore in the plug (30). Apparatus in the plug cooperates with the plurality of channels (84) to define a bayonet type receiving structure dimensioned and configured for receiving the plurality of axially extending ribs (82) and allowing relative rotational movement between the plug (30) and the ribs (82) to produce locking engagement therebetween.
Patent SK-284276-B6 (SK)
Title: Method for operating a DC voltage supplied commutator motor
Inventor: TARGACZ STEFAN
IPC: H02P7/298
Filed: 1996-02-06
Abstract: The motor (1) rotor winding is fed from positive and negative DC supply poles (P, N) via brush connections (A,B) and an excitation winding (2). Initially, one brush (A) is positive and the other (B) is returned to the negative pole (N) via excitation winding connections (E, F) in that order. After the reversal of connections by reversing switches subject to a rotational-speed set-point controller, the direct current flows in the opposite direction through both the brushes and the excitation winding so that the direction of rotation (n) is maintained.
Patent CZ-285031-B6 (CZ)
Inventor: LETEMPS BERNARD
IPC: B65H9/10
Filed: 1990-03-14
Abstract: Při způsobu polohového ustavování tabule skla /1/, posouvající se na dopravníku, při němž se na dráhu tabule skla /1/ vkládá zarážka /60/, proti níž naráží konec předního okraje tabule skla /1/ a která se udržuje v dotyku s tabulí skla /1/ po dobu dostatečnou k tomu, aby tabule skla /1/ byla nově orientována dopravníkem, který pokračuje v unášení tabule skla/1/, je během celé doby ustanování zarážka /60/ poháněna posuvovým pohybem rovnoběžným s posunem skla, a to ve stejném smyslu, jako se posouvá sklo, a s rychlostí nižší, než je rychlost V1 dopravníku. Zařízení pro provádění způsobu obsahuje trám /4/, na němž je upevněna zarážka /60/, přičemž trám /4/ je uložen u každého ze svých konců na kolejnici /8/ rovnoběžné s osou /2/ dopravníku, nesené pohyblivým vozíkem při valivém uložení na valivých prostředcích, přičemž rovnoběžně s osou /2/ dopravníku je uložen šroubový posouvač pro regulovatelný posuv vozíků.ŕ
Patent CZ-278859-B6 (CZ)
Title: System for relief of hydroelectric generator in hydraulic circuits of mobile machines
Inventor: DANKO JOZEF ING
IPC: F15B9/08
Filed: 1992-08-21
Abstract: Connection consists of primary working circuit of relieving circuit and of additional circuit. The primary working circuit contains hydrogenerator (1), switchboard (7) of primary working circuit, working straight hydromotors (15), hydraulic quick couplers (16) and container (11) of medium. Relieving circuit creates the hydraulic switchboard (2), three way throttle valve (3) with stabilization of pressure drop, heck valve (4) of three way throttle valve (5), relieving hydraulic switchboard (6) with spring (18), throttle valve (8), connecting member (9) connecting knot (12) controlling branch (13), alleviate branch (14). Additional circuit contains the additional switchboard (10) and hydraulic quick couplers (19) of additional circuit. Connecting for relieving the hydrogenerator in hydraulic connections of mobile machines is suitable for using in machines and devices which have their hydraulic circuit.
Patent CZ-278376-B6 (CZ)
Title: Table for attaching friction lining of a coal charge compacting devices by sticking
Inventor: KOSEK JIRI ING
IPC: C10B37/04
Filed: 1989-09-22
Abstract: The apparatus consists of a row of semi-closed, solid stands (1) formed by turn plates (2, 3) joined up to the line of the table supports (6), whereas fixed to the solid base there are direct-line hydromotors (8) with heads, supporting the lower heating unit (11). The upper heating unit (19) is fixed from the inside of the upper bracket (18) of the stand (1), equipped in its lower third section by a pair of travelling discs (16, 17), on which the steel beam (20) of the ram is moved into position for sticking operations.<IMAGE>
Patent CZ-279971-B6 (CZ)
Inventor: SAVEL JAN ING CSC
IPC: G01N7/10
Filed: 1990-11-12
Abstract: Podstatou přístroje je oddělené jímání kapaliny,  procházející filtrační vložkou (8) a podílu  kapaliny, unikající obvodem vložky. Pro tento  účel je spodní těsnicí plocha (7) filtrační  nádobky (4) opatřena nejméně jedním otvorem (9)  pro odvod kapaliny, popř. opatřeným sběrnou  trubičkou (10). Vynález se může použít při  kontrole výroby filtračních vložek a při  laboratorní kontrole filtračních vložek u  uživatelů, např. v potravinářském a chemickém  průmyslu.ŕ
Patent CZ-291496-B6 (CZ)
Title: Antisense oligonucleotide and therapeutic compositions containing thereof
Inventor: COLOTE SOUDHIR
IPC: C07H21/00
Filed: 1995-06-27
Abstract: In the present invention there is disclosed an antisense oligonucleotide that  selectively hybridizes with a gene or transcription products for subunits of isoprenyl protein transferases and which is useful in that it inhibits cell proliferation, said oligonucleotide being selected from the group consisting of SEQ ID NOS: 1 to 3, 5 to 7, 23 and 33 to 36, whereby modifications of the main chain consists in the modification of nucleotide bases, in the modification of groups forming a bond and/or the modification of the position 5' and/or 3'. Described is also a therapeutic composition containing as an active substance at least one above-indicated oligonucleotide. The invented antisense oligonucleotide is suitable for treating or therapy of a human or animal body in which the cell proliferation is abnormal and/or uncontrolled.
Patent CZ-284866-B6 (CZ)
Title: Mechanism providing protection against clamping for forcibly controlled closing devices
Inventor: BONNE ANDREAS ING
IPC: E05F15/40
Filed: 1993-09-24
Abstract: The invention relates to a pinching-prevention means for power-operated closure devices, in particular electrically operated windows and sun roofs of motor vehicles, having two spaced-apart electric conductors which, when brought into contact, trigger a switching operation with respect to the drive unit. In the case of said pinching-prevention means, the invention provides, for simple production and reliable contacting, that the pinching-prevention means comprises an elastic hollow profile (10) which consists of an elastomer or plastic and exhibits a planar base region (11) and an attached, convex profile region (12) with the inclusion of a hollow chamber (16), and that the base region (11) and vertex region (13) of the convex profile region (12) consist of a conductive material, said two regions being separated from one another by insulating profile regions (14, 15). <IMAGE>
Patent CZ-298833-B6 (CZ)
Title: Safety catch for firearms
Inventor: GUSSALLI BERETTA UGO
IPC: F41A17/74
Filed: 2002-01-09
Abstract: In the present invention, there is disclosed a safety catch for firearms such as pistols and revolvers having a firing hammer (11) rotating on an axis between a released position and an armed position against the action of a thrust spring (13), the thrust spring (13) being associated and guided with a spring-holder rod (14), the spring-holder rod (14) having an end (15) connected eccentrically to the firing hammer (11) and an opposite free end (16) of and non-circular cross section, the safety catch comprising: a safety body (18) fixable to a part of a stock (40) of the firearm in association with the free end (16) of the spring-holder rod (14), said safety body (18) defining a housing; a safety pin (19) mounted in the housing of the safety body (18) in an arrangement that is aligned with the free end (16) of the spring-holder rod (14) and is capable of axial, rotary translatory movements; and a defined contour key (20) for access and coupling to a profiled part (27) of the safety pin (19) for the rotary translatory movements of the safety pin (19) between a passive, lowered position, which does not affect the spring-holder rod (14) for a normal functioning of the gun, and an active, raised position for the longitudinal blocking of the spring-holder rod (14) for blocking the firing hammer (11) in the released position and inhibiting thus the functioning of the gun.
Patent CZ-295244-B6 (CZ)
Title: Clopidogrel hydrobromide in crystalline form I and process for its preparation
Inventor: HAJICEK JOSEF
IPC: C07D221/00
Filed: 2004-01-13
Abstract: The present invention relates to clopidogrel hydrobromide in crystalline form I being characterized by X-ray diffraction record exhibiting characteristic interplanar spacings d 0.401, 0.439 and 0.317 nm and further being characterized by bands in infrared light 1743, 1421, 1237, 760 and 728 cme-1. Disclosed is also a process for preparing clopidogrel hydrobromide in crystalline form I, which preparation process comprises precipitating clopidogrel base being dissolved in toluene with concentrated solution of hydrobromic acid.
Patent CZ-291653-B6 (CZ)
Title: Electric heating body for injection  or injection molding tools and heated steel plate for injecting or molding tools
Inventor: SCHWARZKOPF EUGEN
IPC: B29C45/73
Filed: 1993-12-16
Abstract: The present invention relates to an electric heating body for injection or injection molding tools having the form of a heating cartridge or a tubular heating body, wherein the heating cartridge or the tubular heating body is provided with a metallic a supple corrugated metal enveloping tube, preferably of steel, in which the heat conductors (1) are held in an insulating material (2), whereby said supple corrugated metal enveloping tube is a corrugated flexible hose (3). Said insulating material (2) filling up the corrugated flexible hose (3) is a compacted powder material based on magnesium dioxide. The heated steel plate for injection or injection molding tools, particularly tools with a hot channel comprises a fundamental plate-like body (6) with a recess    intended for locating therein the electric heating body (8) having the form of a tubular heating cartridge or a tubular heating body wherein said location recess is a shaped channel (7) having the form of a curve. The electric heating body (8), the supple corrugated metal enveloping tube of which is made as a corrugated flexible hose (3) is located in said channel (7). On said electric heating body and/or on said channel (7) there are preferably arranged latching elements, particularly in the form of latching grooves or latching projections for latching connection of the electric heating body (8) with the fundamental plate-like body (6).
Patent CZ-287162-B6 (CZ)
Title: Hydrogenation process of imines
Inventor: JALETT HANS-PETER
IPC: C07C211/48
Filed: 1995-01-21
Abstract: In the present invention there is disclosed a hydrogenation process of imines with hydrogen under increased pressure, in the presence of iridium catalysts and further in the presence or absence of an inert solvent, whereby the reaction mixture contains ammonium chloride, bromide or iodide or metal chloride, bromide or iodide and in addition thereto also an acid.
Patent CZ-298024-B6 (CZ)
Title: Processes for preparing monomeric conjugates of calicheamicin carrier and derivative
Inventor: KUNSTMANN MARTIN PAUL
IPC: A61K47/48
Filed: 1996-05-10
Abstract: In the present invention, there is provided a method for preparing monomeric calicheamicin derivative/carrier conjugates with higher drug loading/yield and decreased aggregation. These conjugates are prepared by incubating a calicheamicin derivative and a proteinaceous carrier in a solution comprising a non-nucleophilic, protein-compatible, buffered solution having a pH in the range from about 4.0 to 8.5 and comprising a cosolvent selected from the group consisting of propylene glycol, ethanol, DMSO, and combinations thereof, and an additive comprising at least one C6-C18 carboxylic acid having 6 to 18 carbon atoms, at a temperature ranging from about 25 degC to about 37 DegC for a period of time ranging from about 15 minutes to about 24 hours, and purifying the conjugate prepared in the step (1)¿to obtain monomeric calicheamicin derivative/carrier conjugates. Alternatively, the conjugates can be prepared by incubating the calicheamicin derivative and a proteinaceous carrier in a solution comprising a non-nucleophilic, protein-compatible, buffered solution and a cosolvent comprising t-butanol.
Patent CZ-292153-B6 (CZ)
Title: Security wall for use with uprights
Inventor: WANDLER KLAUS
IPC: E04B2/58
Filed: 1997-12-17
Abstract: The invented wall secured against burglary  has vertical profiled uprights (1), which each have a wall skin (2) on both sides. The wall skins (2) are attached using only self-tapping screws, which each pass first through a plaster panel, and then through a layer of sheet steel (4). Each wall skin (2) has a second sheet steel layer (6) which is separated from the first (4) one by plaster slabs (3, 5), and whose external side can be also covered by plaster slabs (7). There is formed a layer from the sheet steel panels, which thickness is not greater than 1.5 mm, and which have overlapping joints (8). Each layer (4, 6) has a separate group of quick fastening screws (9, 10, and 11).
Patent CZ-294635-B6 (CZ)
Title: Claw toothing for a gearbox or the like devices
Inventor: GUTMANN PETER
IPC: F16D11/10
Filed: 1997-06-18
Abstract: In the present invention, there is disclosed a claw toothing for a gearbox or the like, wherein the claws are designed with an undercut and, viewed in cross-section with respect to the longitudinal axis of the claws, have a flat or convex roof profile. The invented toothing is characterized in that the plan view of the claws (1, 2) tapers into a wedge shape towards the rotational axis (D) of the claw toothing and that the generatrices (5a, 5b) of the roof profile and/or the sides, in the longitudinal direction of the claw, are straight lines which go through the rotational axis (D).
Patent SK-285539-B6 (SK)
Title: Process for the preparation of a catalyst composition
Inventor: GOSSELINK JOHAN WILLEM
IPC: B01J29/70
Filed: 1998-03-05
Abstract: Process for the preparation of a catalyst composition which comprises, as first cracking component in quan-tities from 0.5 to 40 % weighted a zeolite beta with a silica to alumina molar ratio of at least 20 comprising crystals less than 100 nm in size, and a second cracking component in quantities from 0.5 to 90 % weighted selected from (i) crystalline molecular sieves having pores with diameters greater than 0.6 nm, and (ii) clays in quantities from 0 to 99 % weighted, the process comprising the steps of: (i) preparing a mixture comprising the first cracking component and the second cracking component, the first cracking component being in the form of a sol, (ii) extruding the mixture into catalyst extradites, and (iii) calcimining the extradites.
Patent SK-279779-B6 (SK)
Title: Apparatus for shaping tube ends
Inventor: PAROLA ANDREA
IPC: B21D41/04
Filed: 1994-10-25
Abstract: An apparatus for shaping the end of a tube with an oblong cross-section, in particular with a flat section, to a circular cross-section, in which shaping occurs in a single stage of radial compression from the exterior. Said apparatus is provided with a pair of fixed opposite surfaces (12, 14), whilst each of them has a circular profile with a diameter (R), and a total of angular extensions of the opposite surfaces (12, 14) is complementary to that of shaping surfaces (22, 24). The opposite surfaces (12, 14) are formed on the opposite walls (10) of a longitudinal guide (8) that is formed in a body (6). The shaping surfaces (22, 24), each of them arranged on a front area of the slides (18, 20) respectively, are slidingly mounted in the guide (8).
Patent SK-282902-B6 (SK)
Title: Azole compounds with antimycotic activity for human and veterinary use and pharmaceutical composition containing it
Inventor: ALBINI ENRICO
IPC: C07D233/60
Filed: 1996-04-02
Abstract: Azole compounds of formula (II), wherein R1 is chlorine, fluorine or trifluoromethyl; R2 is hydrogen, chlorine, fluorine or trifluoromethyl; Z is CH or N; R3, R4 and R5, the same or different are hydrogen or C1-C4 alkyl, provided that R4 is different from R5 when R3 is hydrogen; X is O or S; R6 is a C1-C5 polyfluoroalkyl group containing at least two fluorine atoms and optionally other halogen atoms selected among chlorine and bromine; and their salts with pharmaceutically acceptable acids, are described. The compounds of formula (II) are endowed with antimycotic activity for human and veterinary use.
Patent CZ-302861-B6 (CZ)
Title: Braking device for railway stock
Inventor: BECKER DIETMAR
IPC: B61K7/04
Filed: 2001-01-29
Abstract: In the present invention, there is disclosed a railway stock braking device having two fixed brake shoes (16, 18) disposed essentially parallel to a drive rail and displaceable between braking and releasing positions, whereby to achieve the braking position the brake shoes (16, 18) are moved towards each other so that their mutual distance is less than the thickness of a railway vehicle wheel (12). The brake shoes (16, 18) are self-centering relative to the wheel at least in their braking position. Brake levers (20) are assigned to said fixed brake shoes (16, 18). When the wheel (12) runs into the braking device (10), these brake levers (20) are adapted for catching the unilateral force and one brake lever (20) can be deflected to one side about the axis of rotation (22). The brake levers (20) are coupled with each another by power transmission through the mediation of a working means (38) for monitoring movement balancing the deflection by the other non-deflected brake lever (20). One end (28) of the corresponding brake lever (20) is movable in the direction to toward an assigned elastic element (50). During this pendulum motion of the braking device (10), said elastic element (50) bears against a bearing support (58) counter the force of the other elastic element (54). The elastic element (54) is adapted for stabilization of this pendulum motion. The brake shoes (16, 18) are adapted for maintaining their adjusted mutual distance and for producing unlimited braking effect onto the wheel (12).
Patent CZ-303161-B6 (CZ)
Title: Biotechnological preparation process of bovine haemoderivative
Inventor: TRAVNICEK DUUEAN
IPC: A23L33/00
Filed: 2009-02-26
Abstract: In the present invention, there is disclosed a method of biotechnological production of bovine haemoderivative, the method comprising the following step in a time-consecutive sequence: 1) blood fermentation in several phases, for example in two phases; 2) drying the blood fermentation product; 3) disintegration of the blood fermentation product; 4) subjecting the disintegrated blood fermentation product to continual extraction in several phases, preferably in 4 phases, through the action of permanently pure ethanol and preferably in a protective inert atmosphere; 5) stabilization of the thus obtained blood fermentation product extract through separation of undesirable blood salts; 6) vacuum inspissation of the blood fermentation product extract through the subsequent stabilization of the extract and separation of blood salts preferably in a protective inert atmosphere; 7) subjecting the stabilized condensed blood fermentation product extract to ether-ethanol preparation in several phases, for example in 3 phases in order to remove phospholipids; 8) stabilization of the bovine haemoderivative precipitate by separation the residual undesirable ether from this precipitate; 9) vacuum inspissation of the obtained ethanol-ether solution of the bovine haemoderivative, preferably in a protective inert atmosphere; 10) dissolution of the bovine haemoderivative evaporation residue in distilled water; and 11) standardization of the bovine haemoderivative final product.