baber/WOPTO huggingface dataset:
Patent PT-744962-E (PT)
Inventor: SCHNEIDER MICHEL
IPC: A61K49/22
Filed: 1995-12-14
Abstract: Disclosed are suspensions of gas microbubbles immobilised within a frozen aqueous carrier liquid comprising usual additives and stabilisers, in which the carrier liquid is a physiologically acceptable, the immobilised gas microbubbles are microbubbles bound by an evanescent envelope or a tangible membrane. The suspensions, when in liquid form, are injectable and useful as a contrast agents in ultrasonic imaging of blood pool and tissue of living beings. The gas microbubbles are immobilised within the carrier by freezing a suspension of microbubbles with average sizes below 50  mu m, preferably below 10  mu m and more preferably between 2  mu m and 8  mu m, to a temperature between -1 DEG  C. and -76 DEG  C. and maintaining this temperature for prolonged periods of time. The microbubbles may be stabilised by a surfactant such as a lamellar phospholipid or may comprise a membrane made of synthetic or natural polymer or protein. A method of cold storage of microbubble suspensions as well as their use is also disclosed.
Patent PT-851993-E (PT)
Inventor: LILJEDAHL HANS ARNE BERTIL
IPC: F24D11/02
Filed: 1996-09-17
Abstract: PCT No. PCT/SE96/01151 Sec. 371 Date Mar. 18, 1998 Sec. 102(e) Date Mar. 18, 1998 PCT Filed Sep. 17, 1996 PCT Pub. No. WO97/11315 PCT Pub. Date Mar. 27, 1997A method and device for altering the temperature of a premises, wherein a medium in the summertime is cooled by the cool night air and is brought into a floor layer directly under the premises for cooling the premises during the day. In order to minimize the risk of migration of moisture from the ground and upwards to the floor layer, the floor layer and an underlying foundation are cooled so that at least an upper portion of the floor layer reaches a minimum temperature which substantially exceeds the temperature of the ground under the foundation.
Patent PT-854924-E (PT)
Inventor: REED STEVEN G
IPC: A61K38/00
Filed: 1996-09-20
Abstract: Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
Patent PT-888349-E (PT)
Inventor: FREI JORG
IPC: A61K31/519
Filed: 1997-01-13
Abstract: PCT No. PCT/EP97/00127 Sec. 371 Date Jul. 22, 1998 Sec. 102(e) Date Jul. 22, 1998 PCT Filed Jan. 13, 1997 PCT Pub. No. WO97/27199 PCT Pub. Date Jul. 31, 1997There are described compounds of formula I wherein R1 and R2 are as defined in the description, Q is heterocyclyl boned via a ring nitrogen atom and having the formula IA wherein R3 and R4 and m and n are as defined in the description, the ring marked A is a heterocyclyl having 5 to 9 ring atoms and having at least one saturated bond, it being possible for a further ring hetero atom selected from O and S to be present in addition to the bonding nitrogen atom, the ring system marked B is a free or benzo-, thieno-, furo-, pyrrolo- or dihydropyrrolo-fused carbocyclic ring having from 5 to 9 carbon atoms that is fused to the ring A and may be unsaturated, partially saturated or fully saturated, and the bond marked by a parallel dotted line between the ring systems marked A and B is either a single bond or a double bond, and a salt thereof where at least one salt-forming group is present. The compounds are inhibitors of protein kinases and have, for example, antitumour activity.
Patent PT-938584-E (PT)
Title: Method of preparing (s) - or (r) -3,3,3-trifluoro-2-hydroxy-2- methylpropionic acid
Inventor: SHAW NICHOLAS
IPC: C12N1/21
Filed: 1997-07-10
Abstract: The present invention relates to a novel process for the preparation of (S)- or (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid and to novel microorganisms capable of utilizing the propionamide of the formula in the form of the racemate or of its optically active isomers as the sole nitrogen source.
Patent PT-921105-E (PT)
Inventor: BAKALI JORGE BAKALI
IPC: C03C8/04
Filed: 1998-11-28
Abstract: The ceramic enamel is characterized in that it includes in its composition a rare earth oxide (CeO2) along with conventional silicon, aluminum, calcium oxides, etc. Said composition permits the existence of electronic transfers capable of affecting oxidation-reduction processes of live matter that are converted into the bactericidal capacity thereof. The enamel is useful in the ceramic sector. <IMAGE>
Patent PT-872238-E (PT)
Inventor: BYMASTER FRANKLIN PORTER
IPC: A61K31/551
Filed: 1998-04-09
Abstract: The present invention provides a method for treating ALS and for providing a neuro-protective effect comprising administering a therapeutically effective of olanzapine or a pharmaceutically acceptable salt or solvate thereof.
Patent PT-1042160-E (PT)
Inventor: MAMBRETTI RICCARDO
IPC: B63B1/04
Filed: 1998-02-18
Abstract: A V-bottom for fast motor boats with longitudinal reaction walls reacting to a lateral trust from an air-water mixture which are substantially parallel and symmetrical in relation to keel is formed so that the reaction walls are the walls of flat-based grooves in a bottom joined to a flat base by a widely curving radius, or the reaction walls are the walls of ribs having a substantially trapezoidal cross-section and a flat horizontal lesser external base.</PTEXT>
Patent PT-1015352-E (PT)
Title: Blister package and packaged tablets
Inventor: KATZNER LEO D
IPC: B65D75/32
Filed: 1998-04-01
Abstract: The invention is a blister package for containing frangible dosage forms while protecting the dosage forms from damage during transport and opening of the package. A blister sheet defines one or more recesses in which frangible dosage forms are disposed and a peelable sheet of lidding material overlies the recesses to cover the dosage forms therein. The dosage forms engage each recess to prevent shifting of the dosage form during transport. Indicia on the blister package directs the user with regard to the procedure for opening the package without damaging the dosage forms. Unsealed areas in the package, which provide a portion of lidding material which the user can grab to peel open the package, are provided with dimples which hide the grabable portion of lidding material from children.
Patent PT-1084184-E (PT)
Inventor: SPOO KEVIN J
IPC: C08F2/46
Filed: 1999-04-28
Abstract: This invention relates to a method of curing unsaturated polyester resins or mixtures of such resins and a monomer copolymerizable therewith. More particularly, the invention relates to the curing of such resins and mixtures thereof with a composition comprising acetylacetone peroxide (AAP) in an amount of from about 30 to about 35 percent and a high temperature peroxide. Preferably, the high temperature peroxide is t-butyl peroxybenzoate (TBPB) and is present in an amount of from about 5 to about 10 percent of the composition.
Patent PT-1140657-E (PT)
Inventor: VLOOSWIJK JOHANNES JACOBUS THO
IPC: B65D83/66
Filed: 1999-12-14
Abstract: Container with pressure control device for maintaining a substantially constant, preset pressure in the container, said container being arranged for dispensing a fluid, the pressure control device comprising a first chamber for containing a pressure fluid, a second chamber in which a control pressure prevails and a third chamber which is formed by or communicates with, or is at least partially accommodated in an inner space of the container, while between the first chamber and the third chamber there is provided a passage opening accommodating a closing member for closing, during normal use, the passage opening when the pressure in the third chamber is lower than the control pressure, a control means being movable by a displaceable or deformable part of the wall of the second chamber and arranged for displacing the closing member at least partially when the pressure in the third chamber is lower than the control pressure, to enable pressure fluid to flow under pressure from the first chamber to the third chamber, at least the control member and/or the second chamber being at least partially removable from the first chamber and biasing means being provided for keeping the closing member in the closed position when at least the control member and/or the second chamber are at least partially removed.
Patent SG-82784-G (SG)
Title: A programmable cell for use in programmable electronic arrays
IPC: H01L29/68
Filed: 1984-11-19
Abstract: A programmable cell for use in programmable electronic arrays such as PROM devices, logic arrays, gate arrays and die interconnect arrays. The cells have a highly non-conductive state settable and substantially non-resettable into a highly conductive state. The cells have a resistance of 10,000 ohms or more in the non-conductive state which are settable into the conductive state by a threshold voltage of 20 volts or less, a current of 25 milliamps or less, for 1000 microseconds or less. The cells in the conductive state have a resistance of 500 ohms or less. The cells have a maximum permittable processing temperature of 200 DEG  centigrade or more and a storage temperature of 175 DEG  centigrade or more. The cells can be formed from chalcogenide elements, such as germanium tellurium and selenium or combination thereof. The cells also can be formed from tetrahedral elements, such as silicon, germanium and carbon or combinations thereof. Each cell in an array is a thin film deposited cell and includes an isolating device which can be a bipolar or MOS device or can be a thin film diode or transistor. The associated addressing circuitry also can be conventional bipolar or MOS devices or thin film deposited devices. The cells have a cell area of less than one square mil to provide a high cell packing density.
Patent IE-35989-L (IE)
Title: Thiazoline azetidinones
IPC: C07D499/00
Filed: 1972-01-18
Abstract: Novel 2-substituted thiazoline azetidinones are obtained from 2,6-disubstituted thiazoline azetidinones by ozonolysis and solvolysis. Reduction of the 2-substituted thiazoline azetidinones by treatment with aluminum amalgam or sodium borohydride leads to the corresponding thiazolidine azethidinones. The latter class of compounds are useful in the synthesis of penicillins and cephalosporins.
[US3862164A]
Patent IE-870139-L (IE)
Title: PYRROLO (1,2-a) BENZOXAZEPINES
IPC: C07D498/04
Filed: 1987-01-20
Abstract: Disclosed are the compounds of the formula    <IMAGE>  (I)  wherein n represents the integer 1,2,3 or 4; R1 represents hydrogen, lower alkyl, halogen, trifluoromethyl, hydroxy or lower alkoxy; R2 represents hydrogen or lower alkyl; R3 represents hydrogen, lower alkyl or halogen; R4 represents amino, lower alkylamino, di-lower alkylamino, morpholino, N-lower alkyl or N-aryl piperazino, pyrrolidino, piperidino or substituted piperidino selected from <IMAGE>   <IMAGE>  +TR  <IMAGE>  in which R5 represents hydrogen, halogen or lower alkyl; and pharmaceutically acceptable salts thereof; which are useful in mammals as calmodulin antagonists for the treatments of gastrointestinal disorders.
Patent IE-34032-L (IE)
Title: Pipe lagging
IPC: B29C44/58
Filed: 1970-02-24
Abstract: 1297944 Moulding plastic material DUNLOP HOLDINGS Ltd 12 March 1970 [18 March 1969] 14265/69 Heading B5A [Also in Division F2] A mould, Fig. 2, for an insulation sleeve of cellular rubber or plastics material, Fig. 1, is substantially cylindrical and has a rod-like member 21 and extension 22 to produce the bore 11 and split 13 in the sleeve. In the embodiment shown the mould is in two halves, hinged at 18, with locking devices 19 and 20. The rod which may be longer than the mould, is supported by slots in the end surfaces of the mould and the extension 22, which may be integral with the rod, is clamped between the edges 23, 24 of the mould halves when the mould is closed. Other methods of supporting the rod are by a bar across each end face of one half of the mould or by one bar on each half of the mould. The extension may alternatively be formed so that it locks with a corresponding section of each end face. The moulding operation is conveniently carried out by inserting a liquid precursor of the cellular material and then foaming the material, e.g. by the application of heat. The extension 22 is preferably positioned vertically to allow the escape of air from the mould as the foam expands and prevents the formation of undesirable voids. Another method of forming the sleeve is by hot-wire cutting; the split may be cut in a pre-bored cylinder using a split-shaped length of wire (26), the wire may be shaped to cut the bore and split simultaneously (25) or finally an outer circle of wire (28) may be added so that the sleeve can be cut completely from a non-cylindrical block (Figs. 3 and 4, not shown).
[GB1297944A]
Patent IE-37617-L (IE)
Title: 1, 3, 5-triazine derivatives
IPC: C07D251/50
Filed: 1973-05-08
Abstract: 2-Substituted-4-alkylamino-6-( alpha , alpha -dimethyl- beta -acetyl-ethylamino-1,3,5-triazines of the general formula (I) wherein X represents chlorine or a methylthio group, R represents hydrogen or a C1-4 alkyl group, and R' stands for a C1-4 alkyl or alkenyl group, of excellent herbicidal activities are prepared as follows: cyanurchloride is reacted with diacetonamine in a molar ratio of 1:1 in an aqueous or organic solvent medium in the presence of an acid binding agent, the thus-obtained 2,4-dichloro-6-( alpha , alpha -dimethyl- beta -acetyl-ethylamino)-1,3,5-triazine is reacted with an amine of the general formula NHRR' in the presence of an acid binding agent, and if a 2-methylthio compound is to be prepared, the thus-obtained 2-chloro-4-alkylamino-6-( alpha , alpha -dimethyl- beta -acetyl-ethylamino)-1,3,5-triazine is reacted with thiourea and the obtained product is methylated, or the 2-chloro compound is reacted with methylthiol.
[US3892747A]
Patent IE-780797-L (IE)
Title: (2-isopropyl-4-(2'-thenoyl)-5-methyl)-phenoxy acetic acid
IPC: C07D333/22
Filed: 1978-04-21
Abstract: A therapeutic use for a phenoxy acetic acid is disclosed. The compound is effective as a choleretic agent and can be administered orally or intravenously.
[US4254162A]
Patent FI-803572-L (FI)
Inventor: FRIEDRICHS HANS
IPC: B61G9/22
Filed: 1980-11-14
Abstract: 1. Pull gear for rail vehicles, substantially consisting of a support plate (2) connectable to the vehicle, a draw rod (7) which penetrates through the support plate (2), a spring (1), preferably a fraction spring, and a housing (6) surrounding the outer area of the spring (1), the draw rod (7) comprising a coupling member (7a) at its front end and a nut (4) at its rear end, and the spring (1) being supported on the one hand, from the rear with respect to the support plate (2) and, on the other, against a drawing element (5) which is arranged ahead of the nut (4) and - at least when the nut (4) is not yet mounted - rests against an inwardly directed collar (6a) of the housing (6), characterized in that the front end of the spring (1) is supported at the inner face (3a) of a base plate (3) which may be applied from the rear against the support plate (2) ; and in that the housing (6) is connected in a traction-resistant manner to the base plate (3), the spring (1), the base plate (3), the housing (6), and the drawing element (5) forming a pre-stressed assembly unit.
Patent FI-850449-L (FI)
Inventor: LASSEN JORGEN BUUS
IPC: C07D211/22
Filed: 1985-02-04
Abstract: (-)-trans-4-(4-Fluorophenyl)-3-(4-methoxyphenoxy)methyl]piperidine and its acid addition salts are novel compounds of utility in potentiating serotonin. They are prepared by demethylating the corresponding 1-methylpiperidine.
Patent FI-851941-L (FI)
Inventor: LIVINGSTON DOUGLAS ALAN
IPC: C07H15/16
Filed: 1985-05-15
Abstract: A process for preparing 7-halo-7-deoxylincomycin or an analogue thereof, which comprises
 (a) reacting a starting compound selected from lincomycin and analogues thereof, with an amide halide having the formula 
<CHEM>
 wherein each Hal is bromine or chlorine, and either R1 and R2 are independently selected from aryl and C1-8 alkyl or NR1R2 is morpholino or a heterocyclic ring containing 4 to 8 ring atoms selected from carbon and nitrogen, to form an adduct;
 (b) heating the adduct, to form a 7-halo-7-deoxy adduct; and
 (c) hydrolysing the 7-halo-7-deoxy adduct with an aqueous base.
Patent IE-871317-L (IE)
Title: Synergistin derivatives
IPC: C07K7/06
Filed: 1987-05-20
Abstract: The invention provides new synergistin derivatives of formula <IMAGE>  (I)  in which Y is hydrogen or dimethylamino and R is a 3- or 4-quinuclidinyl radical, the isomers thereof and their mixtures, and their salts, also the preparation thereof. These compounds may be made by reaction of the corresponding 5-methylene compounds with the appropriate mercaptoquinuclidine. The products of formula (I), optionally combined with pristinamycin IIA or a derivative of pristinamycin IIB of the formula    <IMAGE> (II)  are useful as antimicrobials.
Patent IE-901409-L (IE)
Title: Anticonvulsant compounds
IPC: A61K31/435
Filed: 1990-04-20
Abstract: There is disclosed a series of triazolopyrimidine compounds and pharmaceutical compositions containing them. The disclosed compounds are useful in the treatment of central nervous disorders, such as epilepsy, in mammals. Methods for the preparation of these triazolopyrimidines are also disclosed.
Patent IE-801423-L (IE)
Title: Bales of compressible material
IPC: B65D71/02
Filed: 1980-07-09
Abstract: The invention concerns a package of at least two layers of rolls of a compressible material. In this package, the rolls of each layer are placed side by side and in mutual contact, while the rolls of two superposed layers are in mutual contact along their lowermost or uppermost surfaces. In addition, the package contains two contoured panels adjacent the outer layers of the rolls, and two bindings bearing on the contoured panels and orthogonally arranged with respect to each other. The invention applies in particular to the packaging of rolls of fibrous insulating materials.
[US4444311A]
Patent IE-32741-L (IE)
Title: Power assisted steering mechanisms
IPC: B62D5/04
Filed: 1968-11-25
Abstract: 1,205,223. Electric power-assisted steering. LANSING BAGNALL Ltd. 19 Nov., 1968 [29 Nov., 1967], No. 54350/67. Heading B7H. In a steering mechanism comprising a steering spindle in two coaxial parts 10, 15 connected by a first gear train 11 to 14, the torque reaction between the gears if to 14 is used to control a reversible electric motor 27 the output shaft 35 of which is connected by a second gear train 36 to 41 to the output spindle port 15 to provide power assistance. The first gear train includes two integral gears 12, 13 on a spindle 19 mounted in a member 22 which is pivotable on bearings 20, 21 on the steering spindle part 10, is centralized by spring-loaded plungers 46 acting on an extension 45 and carries on a pivot 30 an upright support 28 carrying a magnet 32 disposed between two polepieces 33, 34 connected to the pulse-controlled electric motor 27. On rotation of the spindle 10 the reaction on the first gear train rotates the member 22 and hence moves the magnet 32 between the polepieces to alter the flux between them and actuate the motor 27 to provide power assistance to rotate the output shaft 18. As the steering spindle 10 is rotated an internally threaded member 43 engaging the threaded portion 42 of the spindle 10 moves vertically into contact with one of two screws 49 thereby pivoting the support 28 about the pivot 30 and centralizing the magnet 32 to stop the motor 27 and to limit the available steering movement.
[GB1205223A]
Patent IE-791454-L (IE)
Title: Medicinal formulation
IPC: A61K47/22
Filed: 1979-08-08
Abstract: A stable aqueous formulation containing as active substance an active-substance combination consisting of 2,6-diamino-5-(3',4', 5'-trimethoxybenzyl)-pyrimidine (trimethoprim) and either sulfachloropyrazine of the formula <IMAGE> or a salt thereof, or sulfachloropyridazine of the formula <IMAGE> or a salt thereof, for combating bacterial and protozoal diseases in animals by means of drinking water application. Besides the stated active substances, the formulation contains an organic solvent, a solubilizer, a surfactant and water.
[US4423043A]
Patent IE-39993-L (IE)
Title: Reactor.
IPC: B01J14/00
Filed: 1974-07-26
Abstract: PURPOSE: To obtain the title article useful for window glass, having a static contact angle of surface to water of ?a specific value by hydrophilic treatment, excellent non-fogging properties, transparency and scratching properties and high surface hardness, comprising a polymer compound containing P=N skeleton. CONSTITUTION: A polycarbonate resin plate, etc., is coated with a coating solution prepared by blending a curable phosphazene compound shown by formula I (R is group shown by formula II) with methyl isobutyl ketone as a solvent and p-chlorobenzophenone as a photopolymerization initiator, cured by irraidiating with high-pressure mercury lamp light, the laminate is immersed in 20 % aqueous solution of NaOH (25°C) for 20 minutes, washed with water, dried to give the objective hydrophilic article having the surface comprising a polymer compound containing-P=N-skeleton, ?40° static contact angle of surface to water and non-fogging properties, transparency and scratching properties[JPS5051472A]
Patent IE-871852-L (IE)
Title: Angiotensin ii receptor blocking imidazoles.
IPC: C07D233/64
Filed: 1987-07-10
Abstract: Substituted imidazoles such as <CHEM> are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.
Patent IE-40526-L (IE)
Title: Finger joint prosthesis.
IPC: A61F2/30
Filed: 1974-09-27
Abstract: 1461154 Finger endoprostheses E H MILLER and J H DUMBLETON 16 Sept 1974 [28 Sept 1973] 40318/74 Heading A5R A metacarpophalangeal or interphalangeal joint prosthesis comprises a proximal arm 20 and a distal arm 40 articulated together by a hinge structure, the hinge structure comprising a clevis on the distal end of the proximal arm, a gudeon on the proximal end of the distal arm and a pin 60 extending through the gudeon and clevis. The arms have intramedullary stems which each taper away from their respective hinge ends and are of generally rectangular cross section abutments 31 and 51 on the dorsal sides of the arms 20 and 40 respectively limit extension of the joint to 10[] and abutments 30 and 50 respectively limit flexion of the joint to 90[]. The stems are formed with indentations to increase the surface area of the device to aid it's retention by cement, and flanges 25 and 45 are provided at the ends of the stems adjacent the hinge to prevent seepage of cement into the hinge. One branch of the clevis is provided with a slot on its outer face and the pin 60 is provided with a T-shaped head 61 to engage said slot and prevent relative movement between these members. The pin 60 is provided with a counter bore whereby in use, the stems of the two arms are implanted in the resected bones and the pin 60 placed in position, a crimping tool 70 is then used to crimp out the counterbore to hold the pin in position. (From GB1461154 A) [FR2245329A1]
Patent IE-852227-L (IE)
Title: Manufacture of cheese
IPC: A23C19/028
Filed: 1985-09-10
Abstract: A process for the manufacture of higher-solids pre-cheese and cheese from milk retentates wherein a milk retentate is prepared and fermented to a pH of 4.8 to 5.6 without coagulation and a milk clotting enryme is added in a non-coagulating amount but in an amount sufficient to convert about 65 percent of the kappa casein to para kappa casein after evaporation to a total solids of more than about 55 percent.
[EP0174847A2]