baber/WOPTO huggingface dataset:
Patent CA-2899577-A1 (CA)
Inventor: CHANG CHIEN-HSING
IPC: A61K38/21
Filed: 2013-12-14
Abstract: La présente invention concerne des associations de deux agents ou plus pour induire une réponse immunitaire à un cancer ou une maladie infectieuse. Des agents peuvent comprendre des complexes de redirection de leucocytes, des conjugués anticorps-médicament, des interférons (de préférence interféron-a), et/ou des anticorps inhibiteurs de points de contrôle. Les complexes de redirection de leucocytes ont au moins un site de liaison pour un antigène de leucocyte et au moins un site de liaison pour un antigène sur une cellule malade ou un pathogène. De préférence, le complexe est un complexe DNL. De façon davantage préférée, le complexe comprend un anticorps bispécifique (bsAb). De la façon la plus préférée, le bsAb est un anticorps anti-CD3 x anti 19 bispécifique, bien que des anticorps contre d'autres antigènes de leucocyte et/ou antigènes associés à une maladie puissent être utilisés Le complexe est apte à cibler des lymphocytes T effecteurs, des lymphocytes NK, des monocytes ou des neutrophiles pour induire une cytotoxicité à médiation par leucocytes de cellules associées à un cancer ou une maladie infectieuse. La réponse immunitaire cytotoxique est améliorée par co-administration d'interféron, d'anticorps inhibiteur de point de contrôle et/ou d'ADC.
Patent CA-2905131-A1 (CA)
Inventor: YUM SU IL
IPC: A61K47/26
Filed: 2014-03-14
Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
Patent CA-2906934-A1 (CA)
Inventor: SMITH STEVEN W
IPC: G05D1/02
Filed: 2014-03-17
Abstract: The disclosed technology relates to a method and system for localizing and confining an autonomous mobile work system or systems for performing work in a user defined space is disclosed. The system can include two or more variable reflective base stations at first and second locations that can modify their optical or electromagnetic reflectivity based upon either an external command via wired or wireless communications interface, or automatically on a regular or asynchronous time schedule under programmed or user settable control. The system also can include one or more autonomous mobile work systems capable of sensing the state of the variable reflectance base stations via sensors such as electromagnetic or optical sensors capable of measuring distance to the reflective base stations.
Patent CA-2909211-A1 (CA)
Inventor: ARIGONI FABRIZIO
IPC: A23L33/155
Filed: 2014-04-14
Abstract: The present invention generally relates to the filed of medical nutrition. For example, the present invention relates to a composition comprising an amino acid source that in combination with electrical muscle stimulation can be used for the treatment of prevention of sarcopenia, for for reducing the loss of muscle morphology, for increasing the muscle morphology, and/or for improving muscle recovery after muscle atrophy in elderly humans.
Patent CA-2909332-A1 (CA)
Title: A system for processing carcass parts
Inventor: ANDERSON GREG
IPC: A22C17/00
Filed: 2014-04-28
Abstract: A system for processing carcass parts (200) includes an overhead conveyor (201) and a saw module (100) comprising supporting means (101, 112) for interacting with a lower end portion of each incoming carcass part, the supporting means adjusting an angular position of the carcass parts as a result of the carcass parts resting at least partly on the supporting means while being conveyed by the overhead conveyor. A positioning conveyor (102) having a plurality of spaced-apart positioning pair structures (150, 107, 113) arranged below the overhead conveyor and adjacent to the supporting means receives the carcass parts from the supporting means. Each carcass part is guided into a predetermined position within the positioning pair structures and cut at a predetermined position, e.g. defined by a 360° cut through skin and muscle structures of each of the carcass parts.
Patent CA-2909804-A1 (CA)
Title: Method and apparatus for producing an acoustic field
Inventor: CARTER THOMAS ANDREW
IPC: H04S7/00
Filed: 2014-04-29
Abstract: A plurality of control points (10) are defined which each have a known spatial relationship relative to an array of transducers. An amplitude is assigned to each control point (12). A matrix (16) is produced containing elements which represent, for each of the control points, the effect that producing a modeled acoustic field having the assigned amplitude with a particular phase at the control point has on the consequential amplitude and phase of the modeled acoustic field at the other control points (14). Eigenvectors of the matrix (18) are determined, each eigenvector representing a set of phases and relative amplitudes of the modeled acoustic field at the control points. One of the sets (20) is selected and the transducer array is operated to cause one or more of the transducers to output an acoustic wave each having an initial amplitude and phase such that the phases and amplitudes of the resultant acoustic field at the control points correspond to the phases and relative amplitudes of the selected set (22, 24).
Patent CA-2911204-A1 (CA)
Title: Biomarqueurs lies a la fonction renale et methodes d'utilisation de ceux-ci
Inventor: PERICHON REGIS
IPC: G01N33/48
Filed: 2014-05-13
Abstract: L'invention concerne des biomarqueurs de la fonction rénale et des méthodes consistant à utiliser ces biomarqueurs pour évaluer la fonction rénale, diagnostiquer une insuffisance rénale aiguë, et diagnostiquer une néphropathie chronique. L'invention concerne également des suites de petites entités moléculaires utilisées en tant que biomarqueurs d'une néphropathie chronique.
Patent CA-2911235-A1 (CA)
Title: Leads with segmented electrodes and methods of making the leads
Inventor: ROMERO DANIEL JAMES
IPC: A61N1/36
Filed: 2014-05-23
Abstract: A stimulation lead includes a lead body. Terminals and electrodes are disposed along opposing end portions of the lead body and are electrically coupled to one another via conductors. The electrodes include segmented electrodes. Each of the segmented electrodes includes a proximal end, a distal end, an exterior surface, an interior surface opposite the exterior surface, a first side-wall extending radially between the interior surface and the exterior surface from the distal end to the proximal end, and a second side-wall opposite to the first side-wall and extending radially between the interior surface and the exterior surface from the distal end to the proximal end. At least one of the segmented electrodes defines an open cavity that is formed along the first side-wall of the segmented electrode and extends from the distal end to the proximal end, and that facilitates adhesion of the segmented electrode to the lead body.
Patent CA-2913172-A1 (CA)
Inventor: STERN JOEL
IPC: A24F40/485
Filed: 2014-05-28
Abstract: A cartomizer section of an electronic cigarette can be connected to a battery section of the electronic cigarette. The cartomizer section comprises a liquid reservoir operable to store liquid material and a one-way valve. The one-way valve is operable to seal an end of the cartomizer section which is in fluid communication with the liquid reservoir. The one¬ way valve is configured to allow one directional air flow towards a user's mouth during a draw on the electronic cigarette so as to prevent back flow of vapor produced during operation of the electronic cigarette towards the battery section.
Patent CA-2913769-A1 (CA)
Inventor: PATE BROOKS HART
IPC: G01N23/00
Filed: 2014-06-12
Abstract: Examples herein include apparatus and techniques that can be used to perform rotational spectroscopy on gas-phase samples. Such techniques can include using a spectrometer providing frequency synthesis and pulse modulation to provide excitation (e.g., pump or probe pulses) of a gas-phase sample at mm-wave frequencies. Synthesis of such mm-wave frequencies can include use of a frequency multiplier, such as an active multiplier chain (AMC). A free induction decay (FID) elicited by the excitation or other time-domain information can be obtained from the sample, such as down-converted and digitized. A frequency domain representation of the digitized information, such as a Fourier transformed representation, can be used to provide a rotational spectrum.
Patent CA-2915155-A1 (CA)
Inventor: CAHILL SEAN S
IPC: H01L23/50
Filed: 2014-07-02
Abstract: The present invention relates to a die package comprising a die having a plurality of connection pads, a die substrate supporting a plurality of connection elements, a first lead having a first metal core (10) with a first core diameter, and a dielectric layer (20,30) surrounding the first metal core (S1), the dielectric layer (20,30) having a first dielectric thickness that varies along its length and/ or the dielectric layer having an outer metal layer (40, S4) at least partially surrounding the dielectric layer (20,30), for selectively modifying the electrical characteristics of the lead
Patent CA-2920903-A1 (CA)
Inventor: ALBRIGHT CHRISTOPHER MICHAEL
IPC: F23L7/00
Filed: 2015-04-29
Abstract: An oxy-fuel burner (10) with monitoring including a fuel passage (320) terminating in a fuel nozzle (322), a primary oxidant passage (330) terminating in an oxidant nozzle (333), one or more sensors including a nozzle temperature sensor (372) for sensing at least one of an oxidant nozzle temperature and a fuel nozzle temperature, and a data processor (66, 166,266) programmed to receive data from the sensors and to determine based on at least a portion of the received data the presence or absence of an abnormal burner condition including a potential partial obstruction of at least one of the primary oxidant passage (330) and the fuel passage (320) based on an increase or decrease in at least one of the oxidant nozzle temperature and the fuel nozzle temperature.
Patent CA-2921441-A1 (CA)
Inventor: KATRYCZ CHARLES
IPC: B29C59/02
Filed: 2016-02-19
Abstract: A device for producing branched structures is provided which includes an enclosed cell enclosed by two sheets with a port in at least one of the sheets and an injection device connected to the port. The enclosed cell may also include a boundary joining the two sheets. A method is also provided for producing branched structures, wherein fluids of differing viscosities are injected into an enclosed cell and the fluid of lower viscosity branches into the fluid of higher viscosity. The branching of the fluid can be modified using contoured or textured surfaces of the enclosed cell, injecting or evacuating the fluids during branch formation, or impressing a stencil or stamp over a surface of the enclosed cell.
Patent CA-2923370-A1 (CA)
Inventor: GASSER GILLES
IPC: C07F17/02
Filed: 2014-09-26
Abstract: The invention comprises a compound characterized by a general formula (1), wherein OM is an organometallic compound independently selected from the group of an unsubstituted or substituted metal sandwich compound, an unsubstituted or substituted half metal sandwich compound or a metal carbonyl compound, and wherein at least one of RL and RR is selected from formula (A), formula (B), formula (C), or formula (D) and their use for in a method of treatment of disease, in particular their use against helminths.
Patent CA-2927669-A1 (CA)
Inventor: GRYB OLEG
IPC: G06F21/00
Filed: 2014-10-17
Abstract: Virtual asset creation data used to create a virtual asset is generated through a virtual asset creation system that includes primary virtual asset data. Secondary authentication data is also generated. When the virtual asset is launched, the secondary authentication data is passed to the virtual asset from the virtual asset creation system. The primary virtual asset data and secondary authentication data from the virtual asset creation system and the virtual asset, and/or one or more other sources associated with the virtual asset, are then sent to a virtual asset validation system through different communication channels. If the primary virtual asset data and secondary authentication data from the two sources match, or have a defined threshold level of similarity, the status of the virtual asset is transformed to the status of validated virtual asset eligible to receive sensitive data.
Patent CA-2929003-A1 (CA)
Inventor: RAO CHANDRA B
IPC: C08L81/00
Filed: 2014-10-29
Abstract: Sulfur-containing polymer adducts such as polythioethers, polysulfides, and sulfur- containing polyformals having terminal maleimide groups, and in particular, sulfur-containing polymers and sulfur containing adducts having terminal 1,1'-(methylenedi-4,1 - phenylene)bismaleimide groups are disclosed. The adducts provide cured sealants having improved tensile strength and elongation and are useful as aerospace sealants.
Patent CA-2931010-A1 (CA)
Inventor: KOVALCHUK VOLODYMYR
IPC: F16G3/08
Filed: 2014-11-17
Abstract: A fastener for mechanically joining conveyor belts comprises a set of two plates and two connecting members, each of the plates having two identical through openings for the connecting members, which through openings curve inwards from the inside surface of the plate, while the connecting members are in the form of a bolt, the head of which corresponds to a mounting seat in the upper plate; furthermore, each of the plates also has protuberances for attachment to the surface of the conveyor belt. In order to increase the rupture resistance of a joint between conveyor belts, both plates are flat and have cylindrical lugs at the ends thereof for joining the ends of the conveyor belt in the joint, wherein the diameter of the lugs is greater than the thickness of a plate, said plate also having shaped protuberances for attachment to the conveyor belt, which are situated around a circular portion and along the straight portions of the inside surface of the plate, wherein each of the plates is additionally provided with four holes in the circular portions thereof, said holes being arranged symmetrically between the shaped protuberances, and both through openings in the bottom plate are provided with a thread for a bolt.
Patent CA-2931574-A1 (CA)
Inventor: CAPEAU PATRICE
IPC: C02F11/14
Filed: 2014-11-27
Abstract: The invention concerns a method and a device for treating an organic effluent (2, 31). The effluent is fed in a continuous flow at a rate q (m3/h), via a first chamber (5) maintained at a first specific pressure (P1), and/or directly through a first narrowing (7), to a second chamber or container (10, 33, 55) maintained at a second medium specific pressure (P2; P'; P1''; P2'') by the injection of air (11, 31, 54) into said second chamber at a rate Q (Nm3/h), in order to obtain an emulsion (13, 57) in the second chamber, a specific head loss is generated in the emulsion optionally modified by a second and/or third narrowing or a feed valve (61) for a third chamber (22, 39, 62) maintained at a third specific pressure (P3; P'; P3 '') in the region (79) immediately downstream of the second or third narrowing and/or valve (61), and a flocculant (24, 45, 78) is injected into the region of the third chamber, the emulsion at atmospheric pressure then being degasified and the emulsion thus degasified being recovered in a filtration or decanting device.
Patent CA-2933259-A1 (CA)
Inventor: WANG ZHUOZHI
IPC: C12N15/13
Filed: 2009-08-04
Abstract: Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.
Patent CA-2933781-A1 (CA)
Title: Improvements in the design of the absorbent core in diapers for newborn babies
Inventor: SALCEDO AGUALLO JOSE
IPC: A61F13/53
Filed: 2014-12-17
Abstract: The invention relates to an absorbent matrix to be used in a nappy for newborn babies, which has a front part, a rear part and a crotch part, such that the crotch part has a maximum width of 5 cm in order to allow the legs of the baby to form a maximum angle "a" of 30° to the vertical. Said matrix also comprises a base weight of between 700 and 900 g/m2, a density which varies between 0.16 and 0.24 g/cm3,and a ratio of absorbent material / superabsorbent material of 50/50 and 70/30.
Patent CA-2934678-A1 (CA)
Inventor: SAVORY EDWARD
IPC: A61P25/00
Filed: 2014-12-22
Abstract: The invention relates to pharmaceutically active compounds having improved pharmacokinetic properties and being useful for the treatment or prevention of a range of conditions including migraine, epilepsy, non-epileptic seizures, brain injury (including stroke, intracranial haemorrhage and trauma induced) or cardiovascular diseases including myocardial infarction, coronary revascularization or angina. The compounds of the invention form a novel group of related prodrugs of formula (II), where Ar is a 3-chloro-4-fluorophenyl ring, a 3-chlorophenyl ring or a 4-fluorophenyl ring; and R is a hydrolysable group comprising an amino group or an acidic group.
Patent CA-2935130-A1 (CA)
Inventor: KAMALUDEEN MIRZA
IPC: G06F21/56
Filed: 2016-07-26
Abstract: There is provided apparatus, systems and methods suitable for detecting malware in encrypted data. The term malware refers to any computer codes/instructions, which perform actions unauthorized or unwanted by the user, including computer viruses, worms, Trojans and exploits.  Potential applications include, but are not limited to, secure and remote storage systems such as email servers and cloud servers, encrypted devices such as hard drives, USB  flash drives and smart cards. Three approaches, with different properties, are provided for verifying standard hash signatures and generic signatures such as code snippets patterns, using encrypted indices and homomorphic encryptions. The entire scanning process is executed in the encrypted domain. One or more method and system is provided for scanning the files for viruses and malwares. Note that, in our system, the data to be scanned is encrypted under the data owner's private key and not to be confused with polymorphic viruses, which arc data encrypted by the malware writer/code. If a signature compatible to our system can be devised for a polymorphic virus, it can also be detected under the present invention. This system allows storage of encrypted files on cloud computing/storage servers or their passage into secure system, by providing assurance that the encrypted files are free of viruses and malwares that were available to the scanner. It may also provide assurance to the file owner, that their files were not changed, such as when coupled with the invention in "Auditing using Encrypted Indices", that the resident files were not tampered.     One approach involves the data owner encrypting and sending the data files and their indices, in accordance with an encryption scheme, to a storage repository, device, or cloud storage servers.  Another consists of the storage of data encrypted using homomorphic encryption and an anti-virus as a service provider sending encrypted virus/malware signatures, using data owner's public key, for scanning on the storage device/server. This Invention covers three solutions for performing virus scanning over encrypted data, 1) For a private encrypted data storage service/device, where the data owner possesses the anti-virus tools and database 2) For a public encrypted data storage service/device, where the data owner requests the scanning service from an Anti-virus provider, which controls the anti-virus tools and database. 3) For a public unencrypted data storage service/device, where the data owner requests the scanning service from the Anti-virus provider, which controls the anti-virus tools and database.
Patent CA-2935625-A1 (CA)
Title: (2s)-n-[(1s)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase i inhibitors
Inventor: LONN HANS ROLAND
IPC: C07D413/12
Filed: 2015-01-23
Abstract: The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4- oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), (Formula (I)) that inhibit dipeptidyl peptidase 1(DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
Patent CA-2936651-A1 (CA)
Title: Sensor configuration
Inventor: WEGELIN JACKSON WILLIAM
IPC: G08B21/24
Filed: 2015-01-19
Abstract: One or more techniques and/or systems are provided for detecting an object, such as a person. For example, a sensing system may comprise a sensor arrangement. The sensor arrangement may comprise a passive sensor and an active sensor. The active sensor may be placed into a sleep state (e.g., a relatively low powered state) until awakened by the passive sensor. For example, responsive to detecting a presence of an object (e.g., a nurse entering a patient's room), the passive sensor may awaken the active sensor from the sleep state to an active state for detecting motion and/or distance of the object within a detection zone to create object detection data (e.g., an indication of a hygiene opportunity for the nurse). The active sensor may transition from the active state to the sleep state responsive to a detection timeout and/or a determination that the object left the detection zone.
Patent CA-2938392-A1 (CA)
Inventor: NAGURA KENJI
IPC: F17C7/00
Filed: 2015-01-29
Abstract: A gas supply system (2) includes a compressor unit (21), an accumulator unit (23), a pre-cooling system (24) and a housing (4). In the gas supply system (2), the compressor unit (21) is vertically arranged and the pre-cooling system (24) is arranged above the accumulator unit (23) in the housing (4). The compressor unit (21) and the accumulator unit (23) are covered by one rectangular parallelepiped housing (4).
Patent CA-2941776-A1 (CA)
Inventor: KOPP ROBERT G
IPC: B62B5/06
Filed: 2016-09-13
Abstract: In general, the present invention provides a platform truck. More specifically, the present invention provides a platform truck comprised of a base member, a handle, a pair of swivel caster wheels depending from the bottom surface back end of the base member, a pair of swivel-lock caster wheels depending from the bottom surface front end of the base member, and a user-activated actuator assembly carried on the bottom surface of the base allowing the front swivel-lock casters to be switched between a unidirectional position and swivelable position to more easily negotiate tight turns and doorways is disclosed. Also included is a handle that is stowable within the base portion of the platform truck so that the platform truck may include one or two handles, whereby a handle may be included on one or both ends of the platform truck.