baber/WOPTO huggingface dataset:
Patent SG-8595-G (SG)
Title: 5-hetero- or aryl-substituted-imidazo[2,1-A]isoquinolines
Inventor: HOULIHAN WILLIAM JOSEPH
IPC: A61P9/00
Filed: 1995-01-18
Abstract: Compounds of formula I <CHEM> wherein each R independently is hydrogen or methyl R1 is in 8- or 9-position and represents hydrogen, chloro, fluoro or C 1-3alkyl and R2 represents thienyl, furyl or <CHEM> wherein each Ro represents independently hydrogen, fluoro, chloro, C 1-10alkyl, C 1-10alkoxy or C 1-10alkylthio or one Ro is hydrogen and the other represents tri-(C 1-3alkyl)silyl, trifluoromethyl, phenyl, monochlorophenyl, monofluorophenyl, <CHEM> wherein X, Y, R3, R3' or R4 are as defined herein or two Ro's on adjacent carbon atoms form methylenedioxy. The compounds are indicated for use in treating PAF-mediated bronchocontriction and extravasation
Patent IE-830115-L (IE)
Title: Indoline derivatives.
IPC: C07D209/08
Filed: 1983-01-20
Abstract: 3,3-Dialkyl- or 3,3-alkylene-indolines which are unsubstituted at the 1- and 2-positions and which are substituted at the 4- or 6-position by an optionally etherified hydroxy group or substituted at the 5- or 7-position by an etherified hydroxy group, as well as their physiologically-hydrolyzable and -acceptable esters. The said indolines and esters as well as their pharmaceutically acceptable acid addition salts possess analgesic activity.
[US4622336A]
Patent IE-37171-L (IE)
Title: Anti-hypertensive compositions
IPC: A61K31/535
Filed: 1973-01-31
Abstract: 1378102 Antihypertensive compositions GRUPPO LEPETIT SpA 22 Jan 1973 [14 March 1972] 3208/73 Heading A5B Antihypertensive compositions comprise a compound of the general formula wherein R and R 1 are each halogen atoms or C 1-8 alkyl groups, in association with a compound of the general formula: wherein X is H or Cl, R, is H, C 1-8 alkyl, alkenyl or hydroxy-C 1-4 alkyl, R 3 is C,-alkyl, C 2-8 alkenyl, hydroxy-C 1-4 alkyl or phenyl, or R 2 and R 3 together with the nitrogen atom form a heterocyclic ring of 5-7 atoms, R 4 is H 2 or a group =CR 5 R 6 wherein R 5 is H or C 1-8 alkyl and R 6 is C 1-8 alkyl, carboxy or phenyl. The compositions may be in conventional forms for oral and parenteral administration comprising conventional diluents and excipients.
[GB1378102A]
Patent IE-830366-L (IE)
Title: Pharmaceutical compositions containing 3-hydroxybutanoic¹acid
IPC: A61K31/205
Filed: 1983-02-22
Abstract: Pharmaceutical compositions containing a salt derived from 3-hydroxybutanoic acid, such as a sodium salt or alternatively a salt derived from an organic nitrogen base such as an amine; the amine can be an amino-acid of natural origin, such as arginine. The compositions according to the invention can be used for the prophylactic and curative treatment of cardiomyopathy of non-ischaemic and ischaemic origin.
Patent IE-36315-L (IE)
Title: Enzymatic production of l-tryptophan
IPC: C12P13/22
Filed: 1972-04-21
Abstract: 1386674 Filaments containing enzymes SNAM PROGETTI SpA 21 April 1972 [23 April 1971] 18743/72 Heading B5B [Also in Divisions B8 C2 and C3] Enzymes encased in filaments are prepared by dispersing the enzyme in a solution of a polymer capable of producing filaments, and wet or dry spinning the dispersion. Suitable polymers are nitrated or esterified cellulose polymers, polyolefins, homopolymers and copolymers of acrylates, methacrylates, vinyl esters, vinyl chloride, vinylidene chloride and styrene, and polyamides. Enzymes for producing L-tryptophan from indole and serine in the presence of the enzyme-containing filament may be obtained from Escherichia coli, Claviceps, Neurospora, Bacillus subtilis or Saccharomyces. In examples, an enzyme derived from E. coli in a phosphate buffer solution or in aqueous glycerol was emulsified in a methylene chloride solution of cellulose triacetate, the emulsion was poured into a spinneret at 0 C., spun under a nitrogen atmosphere and coagulated in toluene to provide a filament which was then dried under vacuum.
[GB1386674A]
Patent IE-820659-L (IE)
Title: Penicillinate compounds
IPC: C07D499/897
Filed: 1982-03-22
Abstract: Compounds of the formula <CHEM> wherein R<1> is H or HO; Y and Z are each Cl, Br or I, or Y is H and Z is Cl, Br or I; Q is N3 or NHCO2CH2C6H4R<4> where R<4> is H, Cl, Br, NO2, CH3 or OCH3; a process for their use in production of the valuable antibacterial agents 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanate and 1,1-dioxopenicillanoyloxymethyl 6-[2-amino-2-(p-hydroxyphenyl)acetamido]penicillanate, by catalytic hydrogenation in the presence of a noble metal catalyst and novel intermediates useful in preparing said compounds of formula (I).
[EP0061274A1]
Patent IE-32283-L (IE)
Title: Anchoring pin
IPC: F16B19/02
Filed: 1968-08-14
Abstract: 1,228,635. Pins. W. V. WOLFF, and D. BERTELSMANN. 8 Aug., 1968 [14 Aug., 1967], No. 37834/68. Heading F2H. A pin for insertion into a hole drilled in a concrete or like structure for anchorage purposes comprises a tapering shank portion of substantially truncated cone shape and a head 3. The chank 2 may be provided with a cylindrical portion 5 of the same diameter as that of the major diameter end of the tapering portion and may be provided with a tapped hole (4) (Figs. 2, and 13, not shown) or an external thread (12) (Fig. 12, not shown). The shank 2 may be provided with longitudinal or helical ribs or annular grooves.
[GB1228635A]
Patent IE-43831-L (IE)
Title: Prostane derivatives
IPC: C07C67/00
Filed: 1976-05-24
Abstract: 1517562 Silylated prostaglandins IMPERIAL CHEMICAL INDUSTRIES Ltd 20 May 1976 [13 June 1975] 25378/75 Heading C3S [Also in Division C2] Trimethylsilyl derivatives of prostaglandins of the formula wherein R<9>, R<10> and R<11> are Si(CH3)3; either R<3> is Si(CH3)3 and R<4> is H or R<3> and R<4> together form methoxyimino; R<2>, R<5> and R<7> are H or C1-4 alkyl, R<8> is an optionally substituted phenyl or naphthyl radical, m and n are 1 or 2, x is 0 or 1, X is ethylene or vinylene and Y is ethylene or trans-vinylene, and 2-decarboxy-2-trimethylsilyloxymethyl - 9alpha, 11alpha, 15 - tris - (trimethylsilyloxy) - 15 - (trans - 3 - phenylcyclobutyl)- 16,17,18,19,20 - penta - nor - 5 - cis,13 - transprostadienoic acid are prepared by known methods. Reference has been directed by the Comptroller to Specification 1,484,210.
[GB1517562A]
Patent IE-36657-L (IE)
Title: Sizing organic fibrous materials
IPC: D21H17/60
Filed: 1972-08-28
Abstract: 1399921 Sizing inorganic fibrous materials UNITED STATES GYPSUM CO 29 Aug 1972 [27 Dec 1971] 40055/72 Heading D2B A method of sizing inorganic fibrous materials comprises adding a non-cationic waxasphalt emulsion to a slurry of the fibrous materials prior to sheet formation. The emulsion may contain casein as emulsifier. Fillers such as clay or perlite (R.T.M.) and a fireresistant material e.g. sodium borate may be present in the slurry. The inorganic fibrous material may be mineral, glass, or rock wool, or ceramic fibres. Boards formed from the slurry are water-resistant. Kraft gel may be added to the slurry.
[GB1399921A]
Patent IE-38294-L (IE)
Title: Apparatus for moulding drainage blocks.
IPC: B28B7/30
Filed: 1972-10-05
Abstract: 1403985 Surface drainage blocks SAFETICURB LTD 9 Oct 1972 [19 Oct 1971 2 June 1972] 48556/71 and 25814/72 Heading E1G [Also in Division B5] A rectangular, concrete drainage block includes a circular cross-section through-passage and a plurality of tapered slots joining the passage to a face of the block. The faces of the block onto which the passage ends open, include drainage channels (see mould details, Fig 4 not shown). Moulding apparatus for the block is described (see Division B4-B5).
[GB1403985A]
Patent IE-45237-L (IE)
Title: Cleaning nozzles during extrusion
IPC: B29C48/05
Filed: 1977-07-01
Abstract: The invention relates to a method of keeping nozzle bodies or breaker plates clean during extrusion of polymer which can be shaped from the melt which comprises preventing the formation of deposits near the nozzle orifices by gassing these orifices at the point of extrusion of the melt, said gas consisting entirely or partly of vapors of substances which have a depolymerizing action on the deposits formed from the melt at the edge of the nozzle orifice.
[US4124666A]
Patent IE-821445-L (IE)
Title: Rivetted friction stay
IPC: E05D15/46
Filed: 1982-06-17
Abstract: The invention relates to a frictional support for windows or the like. The frictional support consists of a riveted construction, the pivot joint containing, for high efficiency and simpler assembly, a plastic-coated rivet (8) with a frustoconical head (13) seated in a complementary recess (17) which is concentric to a hole (16) in one arm (6) of the support. The arm (6) of the support is connected pivotably to a mounting plate (1) by means of the rivet, the arm (6) and the plate (1) being separated by a spacer (9) which consists of a bearing plate (11) and of a washer (10). The rear end of the rivet is riveted to the underside of the plate (1), in order to generate the desired friction in the joint, and a washer (12) equipped with teeth or spikes is arranged under the rear end of the rivet during the riveting, in order to prevent the rivet from rotating in relation to the plate (1). <IMAGE>
[FR2513300A1]
Patent IE-821475-L (IE)
Title: Benzoyl-phenyl-piperidine derivatives
IPC: C07D/
Filed: 1982-06-22
Abstract: The present invention relates to new benzoyl-phenyl-piperidine derivatives selected from the group consisting of: (i) 2-piperidinobenzophenones of the general formula: <IMAGE> (I) in which: R1, R2 and R3, which are identical or different, each represent an atom of hydrogen, a hydroxy group, CF3, a halogen, a lower alkyl group or a lower alkoxy group; R4 represents an atom of hydrogen, a halogen, an NO2 group, an NR'R'' group [where R' and R'', which are identical or different, represent an atom of hydrogen, a lower alkyl group or a CO2R group (where R represents a lower alkyl group or a benzyl group)]; R5 and R6, which are identical or different, each represent an atom of hydrogen, a C1-C4-alkyl group, an OH group, a phenyl group or a benzyl group; and (ii) acid addition salts thereof. The invention also relates to the method for preparing these new derivatives and to their use in therapeutics, particularly as immunostimulant and immunoadjuvant agents.
[US4528294A]
Patent IE-891767-L (IE)
Title: N-(5,6,7,8-tetrahydropyrido£2,3-d|-pyrimidin-6-yl-alkanoyl)-¹glutamic acid derivatives
IPC: A61K31/519
Filed: 1989-06-12
Abstract: A compound selected from the group consisting of a glutamic acid derivative of the formula: <CHEM>  in which:  R<1> is -OH or -NH2;  R<2> is hydrogen or a carboxy protecting group; R<3> is a carbon-carbon bond, alkylene of 1 to 4 carbon atoms, cyclohexylene, or <CHEM>  R<4> is hydrogen or an amino protecting group;  Q is -S- or -O-;  R<5> is hydrogen, chloro or fluoro; and  the configuration about the carbon atom designated * is S; and the pharmaceutically acceptable salts thereof. Also disclosed is a method of combatting neoplastic growth in a mammal and a pharmaceutical composition for combatting neoplastic growth in a mammal making use of the above compound.
Patent IE-871871-L (IE)
Title: Cloning and expression of acidic fibroblast growth factor
IPC: C12N1/20
Filed: 1987-07-10
Abstract: Unique genes coding for the amino acid sequence of bovine acidic fibroblast growth factor (aFGF) and human aFGF are constructed. The bovine gene is derived from reverse translation of the aFGF amino acid sequence while the human gene is derived by specific point mutations of the bovine gene. Each gene construct is inserted into an expression vector which is used to transform an appropriate host. The transformed host cells produce recombinant aFGF (r-aFGF), human or bovine, which is purified and has an activity equivalent to the native protein.
[EP0259953A1]
Patent IE-41284-L (IE)
Title: Pharmaceutical preparations
IPC: A61K38/16
Filed: 1974-09-11
Abstract: Use of the pregnancy-specific beta 1-glycoprotein (SP1) and its antibody for contraception and for inducing miscarriages.
[US3957975A]
Patent IE-902146-L (IE)
Title: Improvements relating to the Making of Smoking Articles
IPC: A24B15/30
Filed: 1990-06-14
Abstract: Smoking article rod is made by extruding a tobacco/binder mixture, with the addition of water, to provide a rod form extrudate (36), under conditions such that the extrudate (36) is of a cross-section greater than that of the die orifice (16'). The extrudate is drawn down by, for example, passing the extrudate about two driven and peripherally grooved draw down drums (34, 35).
Patent IE-45719-L (IE)
Title: Joint prostheses
IPC: A61F2/36
Filed: 1977-10-28
Abstract: An articulating joint prosthesis comprising implantable first and second members, said first member having a substantially spherical head, said second member having substantially congruent cavity formed therein for cooperatively engaging said spherical head, said cavity having a hemispherical portion terminating in a diametral plane and an entrance portion extending beyond said plane and terminating in a circular entrance to said cavity, an outwardly tapering guideway surrounding said entrance, said second member further having a continuous annular groove formed substantially at said diametral plane and adjacent said guideway, said guideway and said groove defining between them a resilient annular lip surrounding said entrance, said lip being inwardly deformable during insertion of said spherical head through said entrance to admit and entrap said head in said cavity, and said lip being outwardly deformable to resist escape of said head from said cavity.
[US4044403A]
Patent IE-813073-L (IE)
Title: Polymerisation of ethylene
IPC: C08F4/64
Filed: 1981-12-23
Abstract: Catalyst compositions suitable for producing high density ethylene polymers in a low pressure gas phase process with low accompanying ethylene hydrogenation are produced by forming a precursor composition from a magnesium compound, titanium compound and electron donor compound; diluting said precursor composition with an inert carrier material; treating said diluted precursor composition with a boron halide compound: and activating the precursor composition with an organo aluminum compound.A preparative method and a polymerization process are also disclosed.
Patent NO-792421-L (NO)
Title: Fremgangsmaate og apparat for seismisk undersoekelse
Inventor: MONS FRANCIS
IPC: G01V1/42
Filed: 1979-07-23
Abstract: " Fremgangsmåte og apparat for seismisk undersøkelse".
Patent NO-792501-L (NO)
Inventor: GUILLAUME ROBERT
IPC: C25B13/08
Filed: 1979-07-30
Abstract: The invention relates to a permeable diaphragm for an electrochemical cell. The diaphragm consists of a sheet of fibrous, organic polymeric material, obtained from a suspension of the said polymeric material in an organic liquid. The invention applies to permeable diaphragms for cells for the electrolysis of aqueous sodium chloride solutions.
Patent NO-802891-L (NO)
Title: Adhesivpreparat med vaat-adhesjonsegenskaper
Inventor: DIXON DALE DAVID
IPC: C08L33/18
Filed: 1980-09-30
Abstract: Maling omfattende vann, pigment, fortykningsmiddel og en lateks omfattende polymeriserte harpikspartikler inneholdende minst 25 vekt-% vinylacetat og videre inneholdende fra ca. 0,1 til 10 vekt-% kopolymerisert diallylurinstoff representert ved formelen:. der Rog Rer hydrogen, alkyl, fenyl eller hydroksyalkyl;. Rer hydrogen eller lavere alkyl; og Rg Rer hydrogen, metyl eller fenyl.Malingen har gode våt-adhesjonsegenskaper.
Patent NO-820676-L (NO)
Inventor: KERMADEC ALAIN DE
IPC: H04N1/032
Filed: 1982-03-04
Abstract: A multiple stylus print head, e.g. for printing a document in a facsimile system, has at least two parallel lines of styluses with the styluses being offset from one line to the next. Each line of styluses is built up from several tiers of interdigitated conductor pins (C) having tips that constitute the styluses per se. The tiers of pins are held together by respective strips of insulating material (7) forming comb-like structures which are then stacked together in such a manner that the combs fan out from the line of styluses. A plurality of groups (G1, G2) of stylus line forming comb structures are stacked together into a single stack.
Patent NO-840731-L (NO)
Title: Seismikk-kabel
Inventor: SORKIN SAM A
IPC: G01V1/22
Filed: 1984-02-27
Abstract: Antallet av endekontakter, og vekten og diameteren av en oljeflytende, modulær marin seismikk-kabelseksjon blir redusert ved å redusere antallet av både de lokale og de gjennomgående elektriske lederpar, og den oljen som er nødvendig for at kabelen skal flyte, ved å benytte fantompar-teknikken for å sende hydrofonsignalene, hvor impedans-tilpasningstransformatorene i hydrofonkretsene blir brukt som deler av bro-kretsene. Lignende reduksjoner for kabler som mater ladningsforsterkere blir oppnådd ved å bruke kondensator-broer. Oppfinnelsen er også. anvendbar på seismikk-kabler som brukes på land.
Patent NO-842125-L (NO)
Inventor: BROUSSELY MICHEL
IPC: H01M4/58
Filed: 1984-05-29
Abstract: 1. An electrochemical generator of high specific energy comprising a negative electrode (5) on the basis of an alkali or alkaline earth metal, a non-aqueous electrolyte and a positive electrode (2), characterized in that the active material of the positive electrode has the formula Bi12 PbO19 .
Patent NO-853698-L (NO)
Inventor: WUEST HANS-HEINER
IPC: C07C47/575
Filed: 1985-09-20
Abstract: 1-substituted tetralins of the formula I   <IMAGE>   where n, R1, R2, R3, R4, R5 and R6 have the meanings stated in the description, and their preparation are described. The compounds are useful for the treatment of disorders.
Patent NO-873637-L (NO)
Inventor: ROGALSKI GUNTER
IPC: E03F7/00
Filed: 1987-08-28
Abstract: Process and device for the renovation or production of underground piping which comprise the additional internal lining of the pipe with a three-layer flexible tube (9), consisting of an inner and an outer layer (7, 13), of which at least one layer is transparent to radiation and at least one is gas-impermeable, and comprising also an intermediate layer (8) impregneted with a UV-hardening resin (11). The flexible tube is introduced into the pipe (1) and inflated, after which the resin (11) of the intermediate layer (8) is hardened by means of UV radiation produced inside the tube (101, 102; 112, 113; 122, 123, 125). For the manufacture of underground piping, the flexible tube (9) is extended in the open air at the desired position, inflated with air and hardened by natural UV-radiation at the point of storage. The device for renovation is characterized by a supply drum (4) for the intermediate layer (8) of the flexible tube (9) arranged around the inner layer (7), an impregnation arrangement (10) for the intermediate layer (8), a device (12) for covering the impregnated intermediate layer (8) arranged around the inner layer (7) with the outer layer (13), a traction device (16) for inserting the tube (9) into the pipe together with guide and deflection rolls (17), means for propelling the tube (9) fed into the pipe (1) and at least one source of UV radiation (101, 102; 112, 113; 122, 123, 125) for the inner surface of the inflated tube (9).
Patent NO-902352-L (NO)
Inventor: KOGA TOSHIHIKO
IPC: C07K14/315
Filed: 1990-05-28
Abstract: A method for preparing a vaccine for dental caries comprises the step of culturing a variant which is obtained by integrating a protein antigen (PAc)-expressing gene into the chromosomal gene of a Streptococcus mutans GS-5 strain to obtain the protein antigen, the protein antigen being produced on the surface of cells of oral Streptococcus mutans or it being extracellularly produced by the microorganism and having a molecular weight ranging from about 170,000 to 220,000. Streptococcus mutans GS-5 (K-3), in which a protein antigen-expressing gene is integrated into the chromosomal gene thereof, has an ability of producing the protein antigen on the surface of the cells or extracellularly. A preventive vaccine composition for dental caries for nasal drops comprises the protein antigen thus produced by the strain: Streptcoccus mutans, the vaccine being intranasally administered. The method makes it possible to enhance the yield of PAc and to simplify processes for purifying PAc. The vaccine composition makes it possible to internally easily absorb the protein antigen, PAc, in high efficiency and it also makes it possible to effectively increase the antibody titer observed after the administration thereof.
Patent NO-903910-L (NO)
Inventor: HEIMREID BENT
IPC: A61M5/158
Filed: 1990-09-07
Abstract: An intravenous cannula (1) with a bevelled point (2) is designed so as to make the cutting edge (3) of point (2) extend along the portion of the cannula (1) wall which is intended to lie furthest away from the skin (8) in use. The cutting edge (3) is preferably placed along the light opening (6) of cannula (5).
Patent NO-911734-L (NO)
Title: Hoeytalerarrangement.
Inventor: TARKKONEN TIMO
IPC: H04R5/02
Filed: 1991-05-03
Abstract: Oppfinnelsen vedrører et høytalerarrangement for å frem- bringe en tredimensjonal stereolydvirkning. Høytalerarrange- mentet kan lokaliseres i en egnet avstand fra lydreflekterende overflater. Høytalerelementene (12a,13a,14a,12b,13b,14b) til den venstre kanal (2) og den høyre kanal (3) i høytalerarran- gementet er lokalisert inne i en og den samme høytalerenhet (1), idet de er separert fra hverandre ved hjelp av en sone (4) som minst har samme størrelse som intervallet (a) mellom de humane ører. Høytalerelementene er arrangert for utståling mot ulike sider (A, B) fra sonen (4) på tilsvarende måte innenfor sirkelsektorer på 180°, i hvilket tilfelle lydene som reflekteres fra overflatene, sammen med lyden som kommer direkte fra høytalerenheten, skaper en dybdemessig utvidet tredimensjonal stereolydvirkning, hovedsakelig innenfor sekto- ren (10) som strekker seg bort fra høytalerenheten.
Patent NO-913480-L (NO)
Inventor: BOGEN HANS-WERNER
IPC: C09D4/06
Filed: 1991-09-04
Abstract: PCT No. PCT/EP90/00237 Sec. 371 Date Sep. 12, 1991 Sec. 102(e) Date Sep. 12, 1991 PCT Filed Feb. 14, 1990 PCT Pub. No. WO90/10822 PCT Pub. Date Sep. 20, 1990.A process for the manufacture of reflectors, in particular reflectors for automotive vehicle headlamps, wherein a metallic film is applied to a metallization primer cured by UV or electron radiation. The radiation-curable metallization primer comprises A) 10 to 50% by weight of an acrylate copolymer containing ethylenically unsaturated side chains and having a number average molecular weight of 6,000 to 14,000, B) 4 to 50% by weight of a mixture of b1) 2 to 20% by weight of a monomer or oligomer containing three acryloyl groups, b2) 2 to 20% by weight of a polyethylenically unsaturated aliphatic oligomer of the formula (I)    <IMAGE> (I)  b3) 5 to 20% by weight of a difunctional acrylic carbonate monomer, C) 1 to 8% by weight of a photoinitiator, D) 0 to 5% by weight of customary auxiliaries and additives, and E) 0 to 60% by weight of one or more solvents inert toward components A-D  the components A to E in each case totalling 100% by weight.
Patent NO-914014-L (NO)
Title: Elektrisk stimuleringselektrode med impedans-kompensasjon
Inventor: GRUSSING THEODORE
IPC: A61N/
Filed: 1991-10-11
Abstract: Det er beskrevet en fleksibel transkutan elektrisk nerve- og/eller muskelstimuleringselektrode som anvender et ledende materiale, fortrinnsvis en ledende struktur, og en elektrisk 1 shuntinnretning anordnet langs det ledende materialet for å : sarge for mer uniform resistivitet mellom hvilke som helst to 1 likt adskilte punkter på det ledende materialet enn hva som ville vært tilfellet uten den elektriske shuntinnretningen. Ytterligere justering av den elektriske konduktiviteten kan også oppnås ved å variere konduktiviteten til individuelle fibre som anvendes i den ledende strukturen.