baber/WOPTO huggingface dataset:
Patent WO-2020160141-A1 (WO)
Inventor: CHEN HARVEY
IPC: A61F2/24
Filed: 2020-01-29
Abstract: L'invention concerne une prothèse de valvule cardiaque hybride qui peut être implantée rapidement et facilement pendant une intervention chirurgicale. La valvule cardiaque hybride comprend un élément de valvule prothétique sensiblement non compressible et non expansible muni d'une bague d'étanchéité périphérique et d'une armature d'endoprothèse expansible faisant saillie d'une extrémité d'entrée, permettant ainsi une fixation à l'anneau dépourvue de sutures. L'armature d'endoprothèse peut être expansible plastiquement et peut être pourvue d'une fine couche de tissu recouvrant ladite armature d'endoprothèse dans sa totalité ainsi que des structures d'étanchéité secondaires autour de sa périphérie pour prévenir une fuite paravalvulaire. D'autres solutions d'étanchéité comprennent des étapes interactives lors de l'implantation de valvule pour établir des joints d'étanchéité autour de l'endoprothèse et, en particulier, entre l'endoprothèse et la bague d'étanchéité de l'élément de valvule.
Patent WO-2020167943-A1 (WO)
Title: Cast metal products with high grain circularity
Inventor: WAGSTAFF SAMUEL ROBERT
IPC: B22D11/041
Filed: 2020-02-12
Abstract: Systems and methods for making aluminum alloy products are described including those that decrease the tendency for hot tearing or shrinkage porosity to occur during casting by introducing forced convection during the casting process. The forced convection may result in formation of high circularity grains during the solidification process, thereby increasing the permeability of the liquid aluminum alloy and decreasing the tendency for hot tearing or shrinkage porosity to occur.
Patent WO-2020176659-A1 (WO)
Title: Methods and systems for determining the cellular origin of cell-free dna
Inventor: ZOTENKO ELENA
IPC: G16B40/00
Filed: 2020-02-26
Abstract: Provided herein are methods for determining the cellular origin of cell-free DNA. In one aspect, the methods include constructing a distribution of sequence and/or epigenetic information from DNA molecules obtained from a cfDNA sample over a plurality of base positions of a set of differential genomic sections or loci that comprise genomic regions and/or epigenetic loci. The differential genomic loci exhibit one or more properties that differ between at least two cell types. The methods also include processing the distribution of the sequence and/or epigenetic information from the DNA molecules over the set of the differential genomic loci to determine the cellular origin of at least a subset of DNA molecules from the cfDNA sample. Other aspects are directed to methods of treating disease in subjects. Yet other aspects include related systems and computer readable media used to determine the cellular origin of cfDNA.
Patent WO-2020191203-A1 (WO)
Inventor: QUADRI ARSHAD
IPC: A61F2/07
Filed: 2020-03-19
Abstract: A system for treating aortic dissection including an aortic dissection implant comprising an expandable anchoring structure and an elongate tubular structure. The expandable anchoring structure can be configured to apply radial force to the sinuses of the aortic root and/or the sinotubular junction when expanded. The elongate tubular structure can comprise an expandable support frame and one or more layers. The expandable support frame can be configured to extend from the descending aorta to the ascending aorta and curve along with a curvature of the aortic arch when expanded within the aorta. The one or more layers can comprise a first porous layer comprising an atraumatic outer surface positioned over the expandable support frame and a second non-porous layer positioned over a portion of the first porous layer. The second non-porous layer may be configured to be positioned on opposite sides of the aortic dissection and to be inflatable via blood flow to seal against the dissection.
Patent WO-2020191337-A1 (WO)
Title: Methods of applying virtual world elements into augmented reality
Inventor: FISH ROBERT D
IPC: G06F3/01
Filed: 2020-03-20
Abstract: In a method for providing an augmented reality interface for use by a first real-world human user and a second real-world human user, an augmented reality and virtual reality engine (AR-VR engine) produces a visual transformation of the first real-world human user (transformed human user 1), and a visual transformation of a real-world environment around the first real-world human user (transformed environment). The AR-VR engine also produces a virtualized reality world that includes images of transformed first real-world human user moving about, and interacting with, the transformed environment. The AR-VR engine further provides an electronic interface through which the second real-world human user can interact, in real-time, with at least one of the transformed first real-world human user and the transformed environment.
Patent WO-2020219273-A1 (WO)
Title: Double-crowned valve seat insert having seating surface formed of hard-facing material
Inventor: HATTIANGADI ASHWIN A
IPC: F01L3/22
Filed: 2020-04-09
Abstract: A valve seat insert (38) for a gas exchange valve (24) controlling gas exchange of a cylinder (16) includes an insert body (50) having an inner peripheral surface (56), an outer peripheral surface (58), and a valve seating surface (40) structured to contact the gas exchange valve (24) at a closed position and profiled to limit valve recession thereof. The valve seating surface (40) includes an arrangement of linear segments (71) and curved segments (69,73) forming crowns (62,64) to contact the gas exchange valve (24) at different wear states. The valve seat insert (38) further includes a base material (57), and a hard-facing material (61) metallurgically bonded to the base material (57) and forming the valve seating surface (40).
Patent WO-2020210614-A1 (WO)
Inventor: WENNOGLE LAWRENCE P
IPC: A61K31/519
Filed: 2020-04-10
Abstract: La présente invention concerne de nouveaux composés ayant une capacité d'inhibition de PDE1 qui peuvent être utilisés en tant que traceurs pour une utilisation dans des techniques diagnostiques, des biomarqueurs pour la phosphodiestérase 1 (PDE1) in vivo, des méthodes de traitement et/ou de développement de nouvelles thérapies pour des états associés à PDE1, et des méthodes de détection et de traitement.
Patent WO-2020223182-A1 (WO)
Inventor: VANECEK ROMAN
IPC: C09D183/04
Filed: 2020-04-28
Abstract: There is described a primer composition comprising a silicone polyether, a reinforcing filler, one or more polydiorganosiloxane polymer(s) and a carrier and the preparation and use thereof. The primer composition is particularly designed for use with silicone elastomers especially for addition (hydrosilylation) curing silicone elastomers, the preparation thereof, and to a process for improving the adhesion of silicone elastomeric compositions to pre-cured silicone elastomer material substrates.
Patent WO-2020227478-A1 (WO)
Inventor: LAGHI ALDO
IPC: A61F2/60
Filed: 2020-05-07
Abstract: A silicone prosthetic liner for use with a prosthetic assembly that acts as the interface between the residual limb of an amputee and the socket assembly. The prosthetic liner comprises an open proximal end, a closed distal end, and sidewalls comprising an inner layer of molded silicone. The silicone is molded over a mandrel that has been sandblasted using #36 grit at 100 psi so as to form microcraters and reduce the coefficient of static friction.
Patent WO-2020236544-A1 (WO)
Inventor: HRAHA THOMAS
IPC: G16C20/20
Filed: 2020-05-15
Abstract: Described herein are compositions and methods for normalizing the variability of inter-sample analyte measurements from a biological matrix. In some embodiments, the present disclosure relates to methods for normalizing the levels of one or more proteins from urine as measured by an aptamer based assay.
Patent WO-2020243006-A1 (WO)
Inventor: LIPSITZ JONATHAN
IPC: C12N5/078
Filed: 2020-05-22
Abstract: Provided herein are methods of generating a population of enucleated erythroid cells.
Patent WO-2021011207-A1 (WO)
Inventor: VORONENKO YEVGEN
IPC: A61N5/10
Filed: 2020-07-02
Abstract: Disclosed herein are methods for patient setup and patient target region localization for the irradiation of multiple patient target regions in a single treatment session. Virtual localization is a method that can be used to register a patient target region without requiring that the patient is physically moved using the patient platform. Instead, the planned fluence is updated to reflect the current location of the patient target region by selecting a localization reference in the localization image, calculating a localization function based on the localization reference point, and calculating the delivery fluence by convolving the localization function with a shift-invariant firing filter. Mosaic multi-target localization partitions a planned fluence map for multiple patient target regions into sub -regions that can be individually localized. De-coupled multi -target localization involves generating a separate planned fluence map for each target but constraining a cumulative fluence map to ensure dosimetric goals are met.
Patent WO-2021007512-A1 (WO)
Inventor: CHEN JING
IPC: A61K33/04
Filed: 2020-07-10
Abstract: This disclosure relates to methods of treating cancer comprising administering an effective amount of a platinum-based chemotherapy agent in combination with a microtubule associated serine/threonine-protein kinase (MAST) inhibitor and/or a glucocorticoid receptor binding agent and/or a hsp90 binding agent and/or other chemotherapy agents disclosed herein to a subject in need thereof. In certain embodiments, this disclosure relates to pharmaceutical compositions comprising combinations of agents disclosed herein and a pharmaceutically acceptable excipient.
Patent WO-2021007518-A1 (WO)
Inventor: KAUFMAN CHRISTOPHER
IPC: A61M16/00
Filed: 2020-07-10
Abstract: Systems and methods for providing resuscitative chest compressions to a chest of a patient are described. One exemplary system may include a chest compressor for administering chest compressions to the patient, one or more sensors for measuring and generating electrocardiogram (ECG) signals of the patient's heart. The system may include at least one processor coupled to memory and configured to receive and analyze the signals corresponding to the ECG, determine an intrinsic heart rate, identify at least one ECG waveform within the ECG signals, select a chest compression protocol from at least three or at least four predetermined chest compression protocols for administration to the patient based at least in part on the intrinsic heart rate of the patient, and control the chest compressor based on the selected chest compression protocol.
Patent WO-2021011521-A1 (WO)
Title: Catalyseurs de pyrrolidine bloqués par un acide pour mousse de polyuréthane
Inventor: PHAM DIANNE
IPC: C08G18/18
Filed: 2020-07-14
Abstract: La présente divulgation concerne des catalyseurs de pyrrolidine bloqués par un acide destinés à être utilisés dans une formulation de polyuréthane. La formulation de polyuréthane comprend le catalyseur de pyrrolidine bloqué par un acide, un composé contenant un groupe fonctionnel d'isocyanate, un composé contenant de l'hydrogène actif et un composé oléfinique halogéné. L'utilisation de tels catalyseurs de pyrrolidine bloqués par un acide présentent, de manière étonnante, une faible réactivité avec des composés oléfiniques halogénés mais une réactivité suffisante pour catalyser la formation de polyuréthane.
Patent WO-2021041424-A1 (WO)
Inventor: RAMACHANDRAN GANESAN
IPC: H04L47/27
Filed: 2020-08-25
Abstract: La présente invention concerne un terminal terrestre qui permet des communications, par une connexion réseau par l'intermédiaire d'un satellite, entre un hôte local d'un ou plusieurs hôtes locaux connectés et un hôte distant. Le terminal terrestre est conçu pour effectuer des opérations consistant à : recevoir, en provenance de l'hôte distant, un paquet de réseau pour l'hôte local ; obtenir, à partir du paquet de réseau, un segment TCP inclus ; déterminer, à partir du segment TCP, une taille de fenêtre de réception annoncée par l'hôte distant ; calculer, à l'aide d'une ou plusieurs caractéristiques de la connexion réseau, une taille de fenêtre de réception cible ; comparer la taille de fenêtre de réception cible avec la taille de fenêtre de réception annoncée ; et en réponse à la détermination que la taille de fenêtre de réception cible est différente de la taille de fenêtre de réception annoncée : modifier le segment TCP en remplaçant la taille de fenêtre de réception annoncée par la taille de fenêtre de réception cible, et transférer le paquet de réseau avec le segment TCP modifié à l'hôte local.
Patent WO-2021046536-A1 (WO)
Title: Automated information extraction and enrichment in pathology report using natural language processing
Inventor: SHARMA VISHAKHA
IPC: G06K9/00
Filed: 2020-09-08
Abstract: In one example, a method being performed by a computer system comprises: receiving an image file containing a pathology report; performing an image recognition operation on the image file to extract input text strings; detecting, using a natural language processing (NLP) model, entities from the input text strings, each entity including a label and a value; extracting, using the NLP model, the values of the entities from the input text strings; converting, based on a mapping table that maps entities and values to pre-determined terminologies, the values of at least some of the entities to the corresponding pre-determined terminologies; and generating a post-processed pathology report including the entities detected from the input text strings and the corresponding pre-determined terminologies.
Patent WO-2021061677-A1 (WO)
Title: Phosphorus-nitrogen alternative to pfc foam
Inventor: KASOWSKI ROBERT
IPC: C09K21/12
Filed: 2020-09-22
Abstract: An alternative to aqueous film forming foams containing fluorine for firefighting foams for flammable liquid fires is a mist of aqueous ethyleneamine polyphosphate solution or fumed silica doped ethyleneamine polyphosphate solution. The method consists of spraying a mist of such solutions into a flammable liquid fire to suppress the flames and cool the fire. The mist approach also suppresses flames of wood fires. An alternate approach is to add ethyleneamine polyphosphate or fumed silica doped ethyleneamine polyphosphate to a fluorine free foam to form a flame retarded foam that is able to smother a flammable liquid fire.
Patent WO-2021061876-A1 (WO)
Inventor: DEKOSKI KURT
IPC: G01M17/00
Filed: 2020-09-24
Abstract: A hybrid sensor assembly is configured to be mounted on a vehicle to sense structure borne and airborne noises generated as the vehicle travels over the roads. The sensor assembly includes a housing having a circuit board mounted therein, an accelerometer mounted on the circuit board, a microphone mounted on the circuit board, an acoustic port through the housing and in communication with the microphone, and an acoustic fabric attached to the housing over the port. An acoustic shield covers the acoustic port and substantially deters the entry of fluid and debris into the acoustic port.
Patent WO-2021067893-A1 (WO)
Title: Proximity sensor circuits and related sensing methods
Inventor: QUAN XINA
IPC: A61B5/024
Filed: 2020-10-03
Abstract: Disclosed are one or more proximity sensors. At least one of the proximity sensors includes a first dielectric layer, an electrically conductive layer, and an electrode. The first dielectric layer includes an inner surface and an outer surface. The electrically conductive layer is positioned proximate to one of the inner surface or the outer surface of the first dielectric layer. The electrode includes an outer surface. The outer surface of the electrode is positioned proximate the inner surface of the first dielectric layer. The outer surface of the electrode and the electrically conductive layer define a gap.
Patent WO-2021076801-A1 (WO)
Inventor: KAMENCA JENNIFER
IPC: G06Q30/06
Filed: 2020-10-15
Abstract: Techniques are described for using one or more computing devices to perform automated operations related to presenting simulated visualizations of building interior information in a user-customized manner. In at least some situations, the building is a house, and the described techniques include providing a graphical user interface (GUI) that is displayed on a client computing device to an end-user {e.g., as part of a provided Web site), and via which the end-user may customize at least some aspects of the building interior in accordance with defined constraints, such as partner-defined constraints that are specified by a partner entity associated with the house, and/or system-defined constraints that are specified by an operator of the system providing the GUI. Various additional associated functionality and information may be provided in at least some embodiments, including to generate and provide information associated with a particular customization created by a particular end-user.
Patent WO-2021076954-A1 (WO)
Inventor: DINH JAMES QUANG
IPC: A61F2/01
Filed: 2020-10-16
Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A device in accordance with embodiments of the present technology can include, for example, a plurality of interconnected struts forming a unitary structure having a proximal portion and a distal portion. The struts can form a plurality of first cells in the proximal portion and a plurality of second cells, smaller than the first cells, in the distal portion. The device can be pulled against clot material within a blood vessel to engage, disrupt, and/or capture the clot material.
Patent WO-2021113006-A1 (WO)
Title: Obsoleting values stored in registers in a processor based on processing obsolescent register-encoded instructions
Inventor: SARTORIUS THOMAS ANDREW
IPC: G06F9/46
Filed: 2020-11-05
Abstract: Obsoleting values stored in registers in a processor based on processing obsolescent register-encoded instructions is disclosed. The processor is configured to support execution of read and/or write instructions that include obsolescence encoding indicating that one or more of its source and/or target register operands are to be obsoleted by the processor. A register encoded as obsolescent means the data value stored in such register will not be used by subsequent instructions in an instruction stream, and thus does not need to be retained. Thus, such register can be set as being in an obsolescent state so that the data value stored in such register can be ignored to improve performance. As one example, data values for registers having an obsolescent state can be ignored and thus not stored in a saved context for a process being switched out, thus conserving memory and improving processing time for a process switch.
Patent WO-2021113824-A1 (WO)
Title: Stabilization of retromer for the treatment of alzheimer's disease and other neurodegenerative disorders
Inventor: SMALL SCOTT A
IPC: A61P25/28
Filed: 2020-12-07
Abstract: The present disclosure relates to methods and compositions for elevating and stabilizing retromer for treating and/or preventing Alzheimer's disease and other neurodegenerative disorders. Additionally, the disclosure relates to adenoviral based therapy for treating Alzheimer's disease (AD), and other neurodegenerative conditions such as Parkinson's Disease (PD), neuronal ceroid lipofuscinosis (NCL), and transmissible spongiform encephalopathies (TSEs or prion disease), multiple system atrophy (MSA), Down's syndrome, and hereditary spastic paraplegia, as well as tauopathies such as progressive supranuclear palsy (PSP), frontotemporal lobar dementia linked to chromosome 17q21-22 and its subtypes (FTLD-17/FTLD-Tau), Lewy Body Disease (LBD), amyotrophic lateral sclerosis (AES), frontal-temporal degeneration (FTD), ALS-FTD, and chronic traumatic encephalopathy (CTE).
Patent WO-2021133542-A1 (WO)
Inventor: SHI HONGQIN
IPC: G03F7/20
Filed: 2020-12-08
Abstract: The present application relates to contact immersion lithography exposure units and methods of their use. An example contact exposure unit includes a container configured to contain a fluid material and a substrate disposed within the container. The substrate has a first surface and a second surface, and the substrate includes a photoresist material on at least the first surface. The contact exposure unit includes a photomask disposed within the container. The photomask is optically coupled to the photoresist material by way of a gap comprising the fluid material. The contact exposure unit also includes an inflatable balloon configured to be controllably inflated so as to apply a desired force to the second surface of the substrate to controllably adjust the gap between the photomask and the photoresist material.
Patent WO-2021126806-A1 (WO)
Title: Detection of molecular interactions
Inventor: KLEY NIKOLAI
IPC: C12N5/10
Filed: 2020-12-15
Abstract: Methods for detection of molecular interactions, such as protein/protein or small molecule/protein interactions, are described. Accordingly, the present invention relates, in part, to a cell-based system for detecting various molecular interactions. In some embodiments, the present invention provides for methods that allow interrogation of molecular interactions (e.g., protein/protein, protein/small molecule, and/or protein/protein interactions that are modulated by small molecules) which are not detectable using standard assays.
Patent WO-2021127084-A1 (WO)
Title: System and method using hash table with a set of frequently-accessed buckets and a set of less frequently-accessed buckets
Inventor: JAYASENA NUWAN
IPC: G06F16/22
Filed: 2020-12-17
Abstract: A method and apparatus perform a first hash operation on a first key wherein the first hash operation is biased to map the first key and associated value to a set of frequently-accessed buckets in a hash table. An entry for the first key and associated value is stored in the set of frequently-accessed buckets. A second hash operation is performed on a second key wherein the second hash operation is biased to map the second key and associated value to a set of less frequently-accessed buckets in the hash table. An entry for the second key and associated value is stored in the set of less frequently-accessed buckets. The method and apparatus perform a hash table look up of the requested key in the set of frequently-accessed buckets, if the requested key is not found, then a hash table lookup is performed in the set of less frequently-accessed buckets.
Patent WO-2021133664-A1 (WO)
Title: Réglage de volume de champ de vue de capteur de véhicule
Inventor: VERGHESE SIMON
IPC: G01S17/931
Filed: 2020-12-18
Abstract: L'invention concerne tous les exemples de procédé consistant à recevoir, depuis un ou plusieurs capteurs associés à un véhicule autonome, des données de capteur associées à un objet cible dans un environnement du véhicule lors d'une première condition environnementale, au moins un capteur parmi le ou les capteurs pouvant être conçu pour être associé à un volume parmi une pluralité de volumes de champ de vue de fonctionnement. Le procédé consiste également, sur la base des données de capteur, à déterminer au moins un paramètre associé à l'objet cible. Le procédé consiste également à déterminer une dégradation dans ledit paramètre entre les données de capteur et les données de capteur passées, les données de capteur passées étant associées à l'objet cible dans l'environnement lors d'une seconde condition environnementale différente de la première condition environnementale et, sur la base de la dégradation, à régler le volume de champ de vue de fonctionnement dudit capteur selon un volume différent parmi les volumes de champ de vue de fonctionnement.