baber/WOPTO huggingface dataset:
Patent KR-20200042633-A (KR)
Inventor: KIM CHAN JUNG
IPC: B60W10/20
Filed: 2018-10-16
Abstract: The present invention relates to a friction compensation control device of a steering system and, more specifically, to a friction compensation control device of a steering system, which compensates for mechanical friction of the system, which occurs when steering a vehicle, improves steering sensations that a driver feels when steering, improves system responsiveness, and can precisely adjust the steering angle of a vehicle wheel.
Patent KR-20200043212-A (KR)
Inventor: CHOI JAE WON
IPC: A62C31/02
Filed: 2018-10-17
Abstract: The present invention relates to an automatic sprinkler and an operating method thereof which are provided to initially suppress a fire at a place with a very high fire load such as a warehouse. To this end, the automatic sprinkler comprises: a waterway unit (20); a spray unit stopper (6); a spray unit (30); and an operating unit (40). Therefore, the automatic sprinkler can be automatically enclosed after completely extinguishing a fire. In addition, the automatic sprinkler is operated in a waterway blocked state step, a shape memory alloy contraction step, and a shape memory alloy expansion step. Consequently, the shape memory alloy of the sprinkler can be set in accordance with the temperature of an initial fire outbreak in case of a fire, so as to be operated to initially suppress the fire in a more precise manner and to increase the probability of an initial fire suppression against malfunction. In addition, spraying can be automatically stopped after the fire is completely extinguished, thereby reducing inconvenience of having to stop the spraying. Furthermore, the present invention can prevent a secondary damage caused by excessive spraying, and can be re-used unless the present invention is severely damaged. Accordingly, because the present invention can be re-used without being replaced after a fire accident, the present invention can provide economic feasibility and reduce maintenance costs.
Patent KR-20200043797-A (KR)
Inventor: SEO SEONG WON
IPC: C08K7/02
Filed: 2018-10-18
Abstract: The present invention relates to a polyamide resin composition and a molded article manufactured from the same. The polyamide resin composition contains a polyamide resin mixture, a heat stabilizer, and a long fiber reinforcement material, wherein the polyamide resin contains an aliphatic polyamide resin and an aromatic polyamide resin in a weight ratio of 5 : 1 to 3 : 2. The polyamide resin composition has excellent mechanical properties and long-term heat resistance, thereby being able to provide the molded article having high stiffness and improved long-term reliability by preventing deformation.
Patent KR-20200044305-A (KR)
Inventor: PARK EUN SU
IPC: B65D85/72
Filed: 2018-10-19
Abstract: The present invention relates to a beverage container. An auxiliary container is accommodated in a main container. The present invention can maintain the original taste of a beverage.
Patent KR-20200044406-A (KR)
Inventor: KIM JONG CHEOL
IPC: A61B5/00
Filed: 2018-10-19
Abstract: The present invention relates to a system (300) and method for transmitting a message about prediction on a premature birth of a pregnant woman to determine a possibility of a premature birth of a pregnant woman using electrohysterogram biosignal characteristics and quickly respond to a situation by transmitting a text message on emergency to mobile phones of a guardian and a medical staff in charge if a result of the determination falls within a range of possible premature birth. The system (300) comprises: a pregnant woman monitoring system (30); and a text message transmission device (100).
Patent KR-20180122974-A (KR)
Inventor: JEON HYEONG RYEOL
IPC: H01M8/0273
Filed: 2018-10-19
Abstract: Disclosed is a gasket-embedded separator plate for a multi-cell type fuel cell. A connection gasket unit of the disclosed gasket-embedded separator plate includes: a pair of sealing protrusions protruding in at least one direction from the upper side and the lower side as a portion overlapping with a pair of end portions; a center protrusion protruding in the same direction as the protruding direction of the pair of sealing protrusions from the center position of the sealing protrusions; and a pair of protrusion connection units connecting the pair of sealing protrusions and the center protrusion, and having the thickness thinner than the thicknesses of the sealing protrusions and the center protrusion.
Patent KR-20200048048-A (KR)
Inventor: LEE YOUNG AE
IPC: F24F5/00
Filed: 2018-10-29
Abstract: The present invention provides a heat generating device designed to effectively generate warm and cold heat to perform air conditioning. An assembly in which a required number of the heat generating devices are arranged and installed can be applied to a general heat pump type air conditioning device to be used for auxiliary cooling or heating. In addition, when the heat pump type air conditioner is not used, the assembly can be used for main cooling or main heating, and air conditioning is performed without using any complicated parts of a general heat pump type air conditioner or the like. The heat generating device according to the present invention includes a heat transfer pipe of a predetermined length in which an evaporation part and a condensation part are spared at a predetermined distance, a heat source applying heat to the heat transfer pipe, and a working fluid condensed after being evaporated by the heat applied from the heat source, and then returned to the evaporation part.
Patent KR-20200063312-A (KR)
Title: Vehicle, and control method for the same
Inventor: HONG WANG GI
IPC: B60C23/10
Filed: 2018-11-20
Abstract: To intuitively provide the optimal tire pneumatic pressure information corresponding to the weight of a vehicle and the state information of the current tire pneumatic pressure, according to an embodiment of the present invention, the vehicle comprises: a tire pneumatic pressure sensor which is installed on a tire to measure the pneumatic pressure and transmits the measured tire pneumatic pressure as an electric signal; a storage unit which stores the optimal tire pneumatic pressure data corresponding to the weight of the vehicle therein; a control unit which calculates the weight of the vehicle, compares the optimal tire pneumatic pressure corresponding to the calculated weight of the vehicle with the measured tire pneumatic pressure, and generates the state information of the tire pneumatic pressure; and a user interface apparatus which outputs the state information of the tire pneumatic pressure.
Patent KR-20190142193-A (KR)
Title: Terminal apparatus, method of transmitting control command thereof
Inventor: KIM JAE HONG
IPC: F24F11/70
Filed: 2018-11-26
Abstract: The present invention relates to a terminal apparatus and a method of transmitting a control command thereof. According to the present invention, the method of transmitting a control command of the terminal apparatus comprises the following steps of: storing position information of at least one air cleaning apparatus in an indoor space; acquiring region-by-region air pollution information of the indoor space acquired while a moving cleaning apparatus moves in the indoor space; acquiring, based on the acquired region-by-region air pollution information of the indoor space and the position information of the at least one air cleaning apparatus in the indoor space, a control command for controlling an operation of the at least one air cleaning apparatus to supply clean air to a polluted region of regions of the indoor space; and transmitting the acquired control command to the at least one air cleaning apparatus.
Patent KR-20200066435-A (KR)
Title: Vertical pin diodes with improving breakdown voltage and manufacturing method for the same
Inventor: CHA HO YOUNG
IPC: H01L31/0304
Filed: 2018-11-30
Abstract: The present invention relates to a GaN-based photodiode capable of suppressing an electric field of a mesa gradient while maximizing electric field intensity inside an active region. As an avalanche photodiode for detecting ultraviolet light, the photo diode comprises: a GaN-based substrate doped with a first dopant; a GaN-based intrinsic layer doped with the same dopant as the substrate and disposed on an upper part of the substrate; a GaN-based low concentration layer doped with a second dopant and disposed on an upper part of the intrinsic layer; a GaN-based high concentration layer doped with a second dopant, disposed on an upper part of the low concentration layer, and having a higher doping concentration than the low concentration layer; and a pair of electrodes providing ohmic contact and including a first electrode disposed on a lower part of the substrate and a second electrode disposed on an upper part of the high concentration layer, wherein a first mesa isolation surface is formed from a portion of the substrate to the low concentration layer, and a second mesa isolation surface is formed on the high concentration layer to expose a part of a surface of the low concentration layer. In the present invention, the high concentration layer is additionally mesa-isolated to expose a part of the surface of the low concentration layer, and thus, a remarkable voltage drop effect occurs outside the active region to suppress the electric field at the mesa isolation surface, thereby increasing gains with an increased breakdown voltage and a higher electric field inside the active region.
Patent KR-20200066896-A (KR)
Title: System and method of controlling oxygen purge of three-way catalyst
Inventor: CHOUNG JIN WOO
IPC: F02D13/02
Filed: 2018-12-03
Abstract: A method for controlling oxygen purge of a three-way catalyst according to another embodiment of the present invention includes the steps of: performing a fuel cut-off; determining whether a fuel cut-in condition is satisfied after the fuel cut-off; calculating optimum valve overlap according to an intake amount, an engine RPM, and ignition timing when the fuel cut-in condition is satisfied after the fuel cut-off; adjusting a dual continuous variable valve duration device to become the optimum valve overlap; and performing oxygen purge at the optimum valve overlap.
Patent KR-20190069314-A (KR)
Title: Automotive transmission fluid compositions for improved energy efficiency
Inventor: KIM HAHN SOO
IPC: C10M125/04
Filed: 2018-12-06
Abstract: An automatic transmission fluid of the present invention comprises a major amount of an oil of lubricating viscosity and minor amounts of (a) one or more oil-soluble or dispersible molybdenum-containing compounds, and (b) a reaction product of an isomerized alkenyl-substituted succinic anhydride and a polyamine characterized by chemical formula (II). In the chemical formula (II), x and y are independently zero or integers from 1 to 30, where x+y is from 1 to 30, and z is zero or an integer from 1 to 10.
Patent KR-20200069432-A (KR)
Title: Complex type applicator for treating skin condition
Inventor: CHANG HO HYUN
IPC: A61N5/06
Filed: 2018-12-06
Abstract: The present invention relates to a complex applicator for skin care. The present invention comprises: a cover part in which a medium is stored; a facing part which closes the open area of the cover part and allows contact with the skin; an output part which is inserted into the cover part and generates ultrasonic waves when power is applied; a holder part which is coupled to the output part; a support part which is movable by mounting the holder part and closes the inside of the cover part; a connection part which is mounted on the support part and has a substrate part built therein for control; a lid part which is mounted on the connection part and supplies power to the substrate part; and an additional treatment part which is detachable from the cover part and improves the skin condition. Therefore, the present invention can perform complex skin treatment at the same time.
Patent KR-20200069124-A (KR)
Title: System and method for confirmation and valuation of patent information
Inventor: AHN SANG SUN
IPC: G06Q50/18
Filed: 2018-12-06
Abstract: According to the present invention, a system for confirmation and valuation of patent information includes: a patent information confirmation unit that searches for corporate disclosure information on the financial supervisory service site and KIPRIS patent information on the Korean intellectual property office site to confirm the authenticity of target patent information; and a value evaluation information generating unit generating value evaluation information for the target patent information of which authenticity is confirmed.
Patent KR-20190069328-A (KR)
Title: Composition for Tuberculosis Diagnosis and Diagnostic Method for Tuberculosis based on Optical Properties
Inventor: LEE JIN WOO
IPC: G01N33/569
Filed: 2018-12-10
Abstract: The present invention relates to a composition for diagnosing tuberculosis and a method for diagnosing tuberculosis on the basis of a change in optical characteristics. The method for diagnosing tuberculosis is based on a change in optical characteristics of (a) a fluorescent nanomaterial-antibody complex and a fluorescent nanomaterial-antibody complex or (b) a fluorescent nanomaterial-antibody complex and a metal nanoparticle-antibody complex. The method for diagnosing tuberculosis on the basis of a change in optical characteristics according to the present invention can rapidly and accurately measure tuberculosis, which has a low detection limit, since a change in fluorescence intensity of metal nanoparticles and fluorescent nanomaterials is utilized.
Patent KR-20200073900-A (KR)
Title: ring type umbrella handel
Inventor: SONG CHAE WON
IPC: A45B1/00
Filed: 2018-12-16
Abstract: The present invention relates to an umbrella handle which comprises: an end surface magnet (2) installed into an end surface; an end detachable magnet (3) fixed to the same; a strap (4) connecting the detachable magnet (3) and a handle; and a column surface magnet (1). An umbrella of the present invention has an advantage of being able to be easily fixed on top of a metal material.
Patent KR-20190074240-A (KR)
Title: Minimizing body diode conduction in synchronous converters
Inventor: KWON DONGWON
IPC: H02M3/158
Filed: 2018-12-18
Abstract: A synchronous converter comprises a power source, an inductor, an output terminal, and a control circuit. The control circuit includes: an electronic energizing switch which, when activated, delivers energy from the power source to the inductor; an electronic de-energizing switch which, when activated, delivers energy from the inductor to the output terminal, and includes a body diode; and an electronic pull-down switch which, when activated, turns off the electronic de-energizing switch, redirects current flowing though the body diode of the electronic de-energizing switch, and removes charge from the body diode of the electronic de-energizing switch. The electronic energizing switch and the electronic de-energizing switch may never both be activated at the same time.
Patent KR-20200080551-A (KR)
Inventor: KIM HONG MIN
IPC: F04C29/02
Filed: 2018-12-27
Abstract: The present invention relates to a compressor which includes: a casing having a suction chamber and a discharge chamber; a compression mechanism for sucking refrigerant from the suction chamber, compressing the refrigerant and discharging the refrigerant to the discharge chamber; and a heavy object formed of a material having a specific gravity greater than that of the casing and fastened to a wall of the discharge chamber of the casing. Accordingly, the compressor can reduce noise and vibration by preventing the casing from shaking due to a pressure of the refrigerant in the discharge chamber. In addition, the heavy object includes: a body forming the exterior; and an oil separation flow path formed inside the body. Therefore, oil can be sufficiently separated from the refrigerant to prevent the oil from leaking to an outside of the compressor and to prevent the oil amount of the compressor from decreasing.
Patent KR-20200080827-A (KR)
Title: Foot bathing device
Inventor: CHO HANG WOO
IPC: A61H33/02
Filed: 2018-12-27
Abstract: The present invention relates to a foot bath device capable of providing a foot bath while performing sole acupressure and massage. The foot bath device of the present invention includes: a water tank in which water can be contained; a heater for heating water contained in the water tank; a footrest formed in the water tank to allow users to place the feet thereon; and a control unit that receives a signal from a temperature sensor that senses the temperature of water contained in the water tank and controls the operation of the heater to maintain the water at a predetermined temperature.
Patent KR-20200082038-A (KR)
Inventor: HAN SANG MOOK
IPC: E01D101/26
Filed: 2018-12-28
Abstract: The present invention relates to a method for repairing a bridge deck using an ultra-high strength concrete precast plate, and more particularly, to a method for reinforcing and repairing a bridge deck, which remarkably reduces a construction period using a precast plate manufactured by using an ultra-high strength concrete composition, prevents damage by a deterioration phenomenon due to freeze-thawing and calcium chloride, and can extend the operational lifespan. The method according to the present invention comprises: a bridge deck surface treatment step (S100) of installing a plurality of studs on an upper part after a surface of a deteriorated bridge deck is polished; an ultra-high strength concrete composition preparing step (S200) of producing an ultra-high strength concrete composition; an ultra-high strength concrete precast plate manufacturing step (S300) of rooting a glass fiber reinforced plastic (GFRP) root to a cast formed with a tinning shape on an upper part, and pouring the ultra-high strength concrete composition to manufacture an ultra-high strength concrete precast plate after the cast of a hole shape of a shear connector is arranged at a position corresponding to a forming position of the studs of the bridge deck; an ultra-high strength concrete composition applying step (S400) for forming a ultra-high strength concrete composition coating layer by applying the ultra-high strength concrete composition to an upper surface of the prepared bridge deck; and a mounting and finishing step (S500) for pouring and finishing a shear connector part using the ultra-high-strength concrete composition after the ultra-high-strength concrete precast plate is mounted on the upper part of the bridge deck applied with the ultra-high-strength concrete composition.
Patent KR-20200082933-A (KR)
Title: Storage structure of battery housing for electric vehicle
Inventor: JUNG MYEONG SEOP
IPC: H01M2/10
Filed: 2018-12-31
Abstract: A storage structure of a battery housing for an electric vehicle is disclosed. The storage structure of a battery housing for an electric vehicle according to an embodiment of the present invention stores a battery case with a built-in battery module in a battery housing installed under a floor panel of a vehicle body. An upper plate is welded to the upper part of the battery housing to form a storage unit therein, an open storage is formed on both sides of the battery housing, and a plurality of rails are installed in a width direction on the bottom surface of the battery housing to guide rolling balls protruding from both sides of the lower part of the battery case.
Patent KR-20180034395-A (KR)
Title: 뉴럴 네트워크들에서의 러닝 트랜스퍼
Inventor: WIERZYNSKI CASIMIR MATTHEW
IPC: G06N3/04
Filed: 2016-06-27
Abstract: 러닝 트랜스퍼의 방법은 제 2 데이터를 수신하는 단계 및 제 1 네트워크를 통해 제 2 데이터에 대한 제 2 라벨을 생성하는 단계를 포함한다.     일 구성에서, 제 1 네트워크는 제 1 데이터에 대한 제 1 라벨들 상에서 미리 트레이닝되어 왔다.     부가적으로, 제 2 라벨들은 제 2 네트워크를 트레이닝하기 위해 생성된다.
Patent KR-20180019678-A (KR)
Title: 감광성 수지 조성물
Inventor: YOSHIDA MASANORI
IPC: C08F2/50
Filed: 2016-08-19
Abstract: (A) 알칼리 가용성 고분자, (B) 에틸렌성 이중 결합을 갖는 화합물, 및 (C) 광 중합 개시제를 함유하고, (A) 알칼리 가용성 고분자는, 하기 수학식 (I)：{수학식 (I) 중, W i  는 알칼리 가용성 고분자를 구성하는 코모노머 각각의 질량이고, Tg i  는 알칼리 가용성 고분자를 구성하는 코모노머의 각각이 호모폴리머인 경우의 유리 전이 온도이고, W total  은 알칼리 가용성 고분자의 합계 질량이고, 그리고 n 은 그 알칼리 가용성 고분자를 구성하는 코모노머의 종류의 수이다.｝에 의해 구한 유리 전이 온도 (Tg total ) 가 100 ℃ 이하이며, (B) 에틸렌성 이중 결합을 갖는 화합물은, 에틸렌성 이중 결합과 트리아진-트리온 구조를 갖는 화합물을 함유하는, 감광성 수지 조성물.
Patent KR-20180048995-A (KR)
Title: 케이블 앵커리지 시스템
Inventor: ANNAN RACHID
IPC: E01D19/14
Filed: 2015-08-31
Abstract: 토목 공학 구조물에 있는 지지 구조물(1)에 케이블(3)을 앵커링시키기 위한 케이블 앵커리지 시스템(cable anchorage system)이 제공되는바, 상기 케이블 앵커리지 시스템은 상기 케이블(3)에 부착된 앵커리지 소켓(anchorage socket)(4), 상기 지지 구조물(1)에 부착된 지지 소켓(20), 및 상기 앵커리지 소켓(4)을 지지 소켓(20)에 결합시키는 종장형의 결합 로드(coupling rod; 10)를 포함한다.  상기 결합 로드(10)는, 앵커리지 소켓(4) 및 지지 소켓(20)에 해당되는 두 개의 부분 중 하나에 있는 상대측 나사부(counter thread)(4a)와 상호작용하는 나사 단부(threaded end)(10a)와, 반경방향으로 연장된 로드 어깨부(rod shoulder)(10d; 19)를 구비한 장착 단부(10b)를 포함한다. 앵커리지 소켓(4) 및 지지 소켓(20)에 해당되는 두 개의 부분 중 다른 하나는 결합 로드(10)의 장착 단부(10b)를 수용하기 위한 종방향 개구(5)를 포함하고, 상기 개구(5)는 내향으로 연장된 맞닿음 어깨부(abutment shoulder)(20a)를 포함한다.  케이블 앵커리지 시스템의 조정을 위하여 상기 앵커리지 소켓이 지지 소켓을 향하여 움직이게 되는 때에, 제1 길이방향으로 상기 맞닿음 어깨부(20a)에 맞닿는 로드 어깨부(10d)는 개구(5) 내에서 상기 제1 방향의 반대인 제2 길이방향으로 슬라이딩할 수 있다.
Patent KR-20180102536-A (KR)
Title: 디젤 배기 미립자 수집기용 청소 시스템
Inventor: SALSGIVER ROBERT S
IPC: F01N9/00
Filed: 2016-09-15
Abstract: 디젤 미립자 필터를 청소하기 위한 장치는 필터의 청정측 및 오염측에 가압 가스의 펄스를 교호적으로 공급하기 위한 건식 청소 시스템, 및 필터의 청정측 및 오염측에 액체 슬러그를 교호적으로 펌핑하기 위한 습식 청소 시스템을 포함한다.  디젤 미립자 필터를 청소하기 위한 방법은 필터의 청정측 및 오염측에 가압 가스의 펄스를 교호적으로 인가하는 건식 청소 단계, 및 필터의 청정측 및 오염측으로부터 필터를 통해서 교호적으로 급등되는 액체 슬러그로 필터를 습식 청소하는 단계를 포함한다.
Patent KR-20180055854-A (KR)
Title: 분할 쉴드를 갖는 무선 전력 전송 안테나
Inventor: MAYO GABRIEL ISAAC
IPC: H02J50/70
Filed: 2016-08-31
Abstract: 무선 전력 전송을 위한 안테나 구조 (700, 800, 1105) 는, 전기 필드의 통과를 방지하도록 구성된 접지 평면 (838, 1138), 안테나로서 구성되고 접지 평면 위에 위치된 적어도 하나의 코일 (704, 804, 1104) 로서, 상기 접지 평면은 코일에 걸쳐 연속적인, 상기 적어도 하나의 코일 (704, 804, 1104), 접지 평면과 적어도 하나의 코일 사이에 위치된 절연체 (832, 1134, 1136), 및, 코일에 인접한 쉴드로서, 상기 쉴드는 비-연속적인 구조를 포함하고, 상기 쉴드는 적어도 하나의 코일로의 자기 필드의 통과를 허용하도록 구성된, 상기 쉴드를 포함한다.
Patent KR-20180063266-A (KR)
Title: 입력 부재를 구비한 로봇 팔
Inventor: HADDADIN SAMI
IPC: B25J18/00
Filed: 2016-10-04
Abstract: 본 발명은 로봇 팔에 관한 것으로, 로봇 팔은 엑추에이터로 구동될 수 있는 N 개의 관절 연결부 GV n 를 통해 로봇 몸체에 연결될 수 있는 N 개의 팔 부재 A n 를 구비하며, 여기서 n=1, 2, …, N 이다. 로봇 팔의 말단 팔 부재 A N 의 로봇 몸체쪽 단부는 관절 연결부 GV N 을 통해 팔 부재 A N-1 에 연결되고, 몸체에서 가까운 팔 부재의 로봇 몸체쪽 단부는 관절 연결부 GV 1 을 통해 로봇 몸체에 연결된다. 관절 연결부 GV N 은 회전축 D N 에 대해 팔 부재 A N 가 운동할 수 있도록 한다. 로봇 팔의 팔 부재 A N 은 축 L1을 따라 연장되며, 축 L1 및 회전축 D N 은 50°내지 130°범위의 각도를 형성한다. 팔 부재 A N 의 말단 단부는 액추에이터로 구동될 수 있는 관절 연결부 GV N+1 를 통해 이펙터(E)에 연결될 수 있다. 관절 연결부 GV N+1 은 회전축 D N+1 에 대해 이펙터(E)가 회전할 수 있도록 한다. 회전축 D N  및 D N+1 은 50°내지 130°범위의 각도 W1을 형성한다. 축 L1 및 회전축 D N+1 은 50°내지 130°범위의 각도 W2를 형성한다. 팔 부재 A N 은 회전축 D N+1 에 대해 동심원으로 연장되며 팔 부재에 견고하게 연결되는 그립(grip)과 같은 돌출부(F1)를 갖는다. 돌출부(F1)의 자유 단부(FE)는 회전축 D N+1 을 중심으로 하여 돌출부(F1)의 잔여단(rest)에 대해 회전할 수 있거나 또는 회전축 D N+1 을 중심으로 회전가능하게 구비될 수 있으며, 자유 단부(FE)는 데이터의 수동 입력을 위한 입력 부재(EE)를 구비하는 점을 특징으로 한다. 본 발명의 로봇 팔은 이러한 팔을 가진 로봇의 교시 프로그래밍 공정을 수행하는 동안에 개선된 인체공학적 조작을 가능하게 한다.
Patent KR-20180097517-A (KR)
Title: 매우 안정된 인슐린 유사체의 중합체 용융물 내 캡슐화
Inventor: WEISS MICHAEL
IPC: A61K9/00
Filed: 2016-12-23
Abstract: 인슐린 조성물은 인슐린 유사체 및 중합체 블렌드를 포함한다. 상기 인슐린 유사체는 (시스틴 B4-A10을 형성하기 위한) 위치 B4 및 A10에서의 시스테인 치환, 및 다음으로 이루어진 군으로부터 선택된 하나 이상의 추가적 치환을 포함한다: 인슐린 A 및 B 도메인 사이의 5 내지 11개 아미노산의 연결 도메인; 위치 A8에서의 비-베타-분지형 아미노산 치환; 위치 A14에서의 비-베타-분지형 산성 또는 극성 측쇄; 오르토 위치에서의 Phe B24 의 할로겐 변형; 및 Glu, Ala, Val, Ile, Leu, 아미노-프로피온산, 아미노-부티르산 또는 노르류신에 의한 B29 위치에서의 리신의 치환. 상기 인슐린 유사체는 90℃ 내지 120℃의 온도 범위에서의 하나 이상의 단계를 포함하는 제조 공정에 적합하다. 캡슐화된 인슐린 유사체는 유리 PEG를 선택적으로 함유하거나 페길레이트될 수 있다. 인슐린 유사체-캡슐화된 중합체 블렌드는 국소 투여용 마이크로 바늘 패치 또는 피하 주사용 마이크로 펠릿으로 주조될 수 있다.
Patent KR-20180063324-A (KR)
Title: Tgf-베타 슈퍼패밀리 단백질의 개선된 정제
Inventor: BROWN CHRISTOPHER T
IPC: B01D15/38
Filed: 2016-10-21
Abstract: 골형성 단백질 예컨대 골 형태발생 단백질 (BMP)을 포함하는, TGF-β 슈퍼패밀리 단백질의 정제 방법이 개시된다.