baber/WOPTO huggingface dataset:
Patent AU-1865883-A (AU)
Title: 1, 4-dihyrdopyridine derivatives
Inventor: CAMPBELL SIMON FRASER
IPC: C07D295/14
Filed: 1983-09-02
Abstract: 1,4-Dihydropyridine derivatives of the formula:-and their pharmaceutically acceptable acid addition salts; whereR is aryl or heteroaryl;R<sup>1</sup> and R<sup>2</sup> are each independently C<sub>1</sub>-C<sub>4</sub> alkyl or 2-methoxyethyl;Y is -(CH<sub>2</sub>)<sub>2</sub>-, -(CH<sub>2</sub>)<sub>3</sub>-, -CH<sub>2</sub>CH(CH<sub>3</sub>)- or -CH<sub>2</sub>C(CH<sub>3</sub>)<sub>2</sub>-;R<sup>3</sup> is hydrogen or a group selected from:-where R<sup>4</sup> is H, C<sub>1</sub>-C<sub>4</sub> alkyl, C<sub>3</sub>-C<sub>6</sub> cycloalkyl, -COO(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>COO(C<sub>1</sub>-C<sub>4</sub> alkyl), aryl, -S0<sub>2</sub>.aryl, or heteroaryl, and X is 0 or S;where R<sup>5</sup> is 1-pyrrolidinyl, -NH<sub>2</sub>, -NH(C<sub>1</sub>-C<sub>4</sub> alkyl), -N/C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub>, or -NH(CH<sub>2</sub>)<sub>2</sub>N(C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub>;where R<sup>6</sup> is C<sub>1</sub>-C<sub>4</sub> alkyl or aryl;where R<sup>7</sup> is -CONH(C<sub>1</sub>-C<sub>4</sub> alkyl) or -COO(C<sub>1</sub>-C<sub>4</sub> alkyl);where R<sup>8</sup> is -CN, -SO<sub>2</sub>(C<sub>1</sub>-C<sub>4</sub> alkyl) or -SO<sub>2</sub> aryl;(h) -CH<sub>2</sub>CO.R<sup>9</sup> where R<sup>9</sup> is -NH<sub>2</sub>, -NH(C<sub>1</sub>-C<sub>4</sub> alkyl), -NH.aryl or C<sub>1</sub>-C<sub>4</sub> alkoxy;(i) -SO<sub>2</sub>.R<sup>10</sup> where R<sup>10</sup> is -NH<sub>2</sub>, -N(C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub> or C<sub>1</sub>-C<sub>4</sub> alkyl; and(j) -CO.R" where R" is H, halomethyl, -COO(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>O(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>CO(C<sub>1</sub>-C<sub>4</sub> alkyl), C<sub>1</sub>-C<sub>4</sub> alkyl, C<sub>1</sub>-C<sub>4</sub> alkoxy, aryl, heteroaryl, morpholino or 5-oxo-pyrrolidin-2-yl.The compounds have utility as anti-ischaemic and antihypertensive agents.
Patent AU-1943588-A (AU)
Title: Scarifier-edger adossable to a small power-driven cultivator
Inventor: MOISE RENE FRANCK
IPC: A01B33/02
Filed: 1988-05-24
Abstract: PCT No. PCT/FR88/00265 Sec. 371 Date Jan. 23, 1989 Sec. 102(e) Date Jan. 23, 1989 PCT Filed May 24, 1988 PCT Pub. No. WO88/09113 PCT Pub. Date Dec. 1, 1988.A power operated hand guided device is designed to scarify, edge, and aerate lawns and grass. It comprises tools in the form of blades (26) which rotate in a vertical plane about the common axis of a pair of tool-holder shafts. Each tool holder shaft (21) is rotatably connected to a bearing (12) supported on a vertically adjustable beam (23) having wheels (24 and 25) or rollers at each end. A brake (37) which retards the forward movement by friction with the ground is connected to the motor assembly by a rod (38).
Patent AU-2052692-A (AU)
Title: A plastics tube head provided with a lining having a barrier effect and a member which can be used for this lining
IPC: B65D1/02
Filed: 1992-07-23
Abstract: The subject of the invention is a tube head (1) having a barrier-effect inner coating (7), characterised in that this coating (7) consists of a multilayer polymeric element secured by an outer superficial layer (9) of the said element to the annular plastic covering (8) of the head (1), the said element (7) comprising moreover one or more polymeric barrier-effect layers (11) having a total thickness of between 0.008 and 0.05 mm and an inner superficial polyolefin or polyester layer (6). The subject of the invention is also the thermoformed single-piece part (7) which becomes this inner coating element. It is applicable to the manufacture of numerous tubes. <IMAGE>
Patent AU-2093001-A (AU)
Title: Detection of transmembrane potentials by optical methods
Inventor: TSIEN ROGER Y
IPC: C09K11/06
Filed: 2000-12-12
Abstract: Methods and compositions are provided for detecting changes in membrane potential in membranes biological systems. In one aspect, the method comprises; a) providing a living cell with a first reagent comprising a charged hydrophobic molecule which is typically a fluorescence resonance energy transfer (FRET) acceptor or donor, or is a quencher and is capable of redistributing within the membrane of a biological membrane in response to changes in the potential across the membrane; b) providing the cell with a second reagent that can label the first face or the second face of a biological membrane within the cell; c) detecting light emission from the first reagent or the second reagent. One aspect of this method involves monitoring membrane potential changes in subcellular organelle membranes in a living cells. Another aspect of the invention is the use of certain embodiments of the method for the screening of test chemicals for activity to modulate the activity of a target ion channel. Another aspect of the present invention is a transgenic organism comprising a first reagent that comprises a charged hydrophobic fluorescent molecule, and a second reagent comprising a bioluminescent or naturally fluorescent protein.
Patent AU-2201792-A (AU)
Title: Bathroom tissue and process for producing the same
IPC: B32B29/02
Filed: 1992-09-01
Abstract: A toilet paper comprising an intermediate layer having on one side thereof a top layer and the other side thereof a bottom layer characterized in that said intermediate layer comprises about 100% wood pulp and said top and bottom layers comprises wood and rayon pulps as mixed in a weight ratio of about 40-80:60-20 is disclosed. A process for producing the same is also disclosed.
Patent AU-2238397-A (AU)
Title: Iscom or iscom-matrix comprising hydrophobic receptor molecules for antigenic substances
Inventor: MOREIN BROR
IPC: A61K9/00
Filed: 1997-02-20
Abstract: PCT No. PCT/SE97/00287 Sec. 371 Date Sep. 17, 1998 Sec. 102(e) Date Sep. 17, 1998 PCT Filed Feb. 20, 1997 PCT Pub. No. WO97/30726 PCT Pub. Date Aug. 28, 1997Lipid-containing particles such as iscoms, iscom-matrix or vesicles such as micelles or liposomes that comprise one or more hydrophobic receptor molecules for targeting and antigenic substances, which receptor molecules have been integrated in the particle and are chosen from lipid-containing receptors or receptors that are hydrophobic, which receptor molecules bind to the antigenic substances.
Patent AU-2275188-A (AU)
Title: Inductive collagen-based bone repair preparations
Inventor: CHU GEORGE
IPC: A61K38/00
Filed: 1988-09-23
Abstract: An improved process for the preparation of mineral/collagen/OF (osteogenic factor) inductive implants for bone repair utilizes drying, under ambient pressure conditions, a suspension of 75-95% mineral particles, 5-25% collagen, and an effective amount of OF, such as 0.5-4% partially purified OFE or its equivalent wherein the concentration of collagen in the suspension subjected to drying is 30-100 mg/ml. The resulting implants are improved. They are homogeneous in composition and have a high compressive modulus as well as containing OF in a biologically active and available form.
Patent AU-2284592-A (AU)
Title: Preparation of a cephalosporin antibiotic using the syn-isomer of a thiazolyl intermediate
IPC: A61K31/546
Filed: 1992-09-09
Abstract: The present invention provides an aqueous acylation process for the preparation of antibiotic, cefepime dihydrochloride hydrate which is substantially free of the anti-isomer and the  DELTA <2> isomer comprising the N-acylation of 7-amino-3-[(1-methyl-1-pyrrolidinio)-methyl]ceph-3-em-4-carboxylate with the syn-isomer of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetyl chloride hydrochloride.
Patent AU-2476195-A (AU)
Title: Continuous method of grinding pharmaceutical substances
Inventor: CZEKAI DAVID A
IPC: A61J3/02
Filed: 1995-05-08
Abstract: A continuous method of preparing submicron particles of a therapeutic or diagnostic agent comprises the steps of continuously introducing the agent and rigid grinding media into a milling chamber, contacting the agent with the grinding media while in the chamber to reduce the particle size of the agent, continuously removing the agent and the grinding media from the milling chamber, and thereafter separating the agent from the grinding media. In a preferred embodiment, the grinding media is a polymeric resin having a mean particle size of less than 300  mu m. In another preferred embodiment, the agent, grinding media and a liquid dispersion medium are continuously introduced into the milling chamber. In a further embodiment, the agent and grinding media are recirculated through the milling chamber. The method enables the use of fine grinding media, e.g., of a particle size of less than about 300  mu m, in a continuous grinding process which provides extremely fine particles of the agent, e.g., particles less than 100 nm in size, while avoiding problems, e.g., separator screen plugging, associated with prior art processes requiring the separation of agent from the grinding media in the milling chamber.
Patent AU-2494592-A (AU)
Title: Apparatus for arresting the progress of vehicles
IPC: E01F13/04
Filed: 1992-09-01
Abstract: PCT No. PCT/GB92/01598 Sec. 371 Date May 4, 1994 Sec. 102(e) Date May 4, 1994 PCT Filed Sep. 1, 1992 PCT Pub. No. WO93/05236 PCT Pub. Date Mar. 18, 1993An apparatus comprising a plurality of releasably connected modules adapted to be placed on a road surface for arresting the progress of a vehicle. Each module is equipped with a number of blades which can be protruded or retracted to respectively arrest or allow the passage of vehicle thereover. The modules are interconnected in a manner which enables simultaneous actuation of all the blades and compensates for the camber of the road surface or the misalignment of the modules.
Patent AU-2502088-A (AU)
Title: A multiple focal point profiled phase plate
Inventor: COHEN ALLEN L
IPC: G02C7/04
Filed: 1988-11-10
Abstract: This invention relates to a multifocal optical lens configuration that relies on the phenomenon of simultaneous vision whereby the eye is presented with two clear images at once. In particular this invention allows a lens to be made with arbitrary relative brightnesses between the multiple images. Thus, for example, the lens can comprise a carrier lens CL, the anterior surface I of which is divided into six concentric annular zones, bounded by radii r1-r6 in such a manner as to form a trifocal phase plate.
Patent AU-2528388-A (AU)
Title: Semi-permeable membranes with an internal discriminating region
Inventor: SANDERS EDGAR S JR
IPC: C08G64/10
Filed: 1988-09-14
Abstract: The invention is a semi-permeable membrane which comprises a polymeric matrix with two porous surfaces and a region which functions to separate one or more gases from one or more other gases. A composition is disclosed that is useful for the preparation of a bisphenol-based polycarbonate membrane wherein at least 25 percent by weight of the bisphenol moieties are tetrahalogenated, preferably Cl or Br. The composition includes (i) a bisphenol-based polycarbonate wherein at least 25 percent by weight of the bisphenol moieties are tetrahalogenated, wherein the halogen is Cl or Br, (ii) a solvent for such polycarbonate, and (iii) a non-solvent for such polycarbonate. A process is described wherein the composition is heated and extruded into a shape suitable for membrane use such as a hollow fiber. The formed membrane is then passed through a quench zone wherein the mixture undergoes phase separation, and the solvent non-solvent are removed and a discriminating region capable of separating oxygen from nitrogen is formed. The membranes of this invention exhibit excellent separation factors and flux. Such membranes are less prone to being damaged due to handling and exposure to contaminants due to the internal region which affects the separation, as the porous surfaces function to protect such region.
Patent AU-2585188-A (AU)
Title: New N-(23-vinblastinoyl) derivatives of 1-aminomethyl- phosphonic acid, processes for preparing them and pharmaceutical compositions containing them
Inventor: LAVIELLE G
IPC: C07F9/547
Filed: 1988-11-24
Abstract: N-(23-Vinblastinoyl) derivatives of 1-aminomethylphosphonic acid, of general formula I: 
<IMAGE>
 
<??>In which:
 - R1 denotes a hydrogen atom, a linear or branched alkyl radical containing from 1 to 6 carbon atoms, a linear or branched alkylene radical containing from 1 to 6 carbon atoms, an arylalkyl radical of 7 to 10 carbon atoms capable of carrying as substituent on the aromatic ring a halogen atom, a hydroxyl radical or an alkyl or alkoxy radical, each containing from 1 to 5 carbon atoms, a 2-indolylmethyl radical, a 4-imidazolylmethyl radical, or an alkoxycarbonylmethyl radical containing from 3 to 11 carbon atoms,
 - each of R2 and R3, which are identical or different, denotes a linear or branched alkyl radical containing from 1 to 4 carbon atoms,
 in the form of mixture of diastereo isomers or of pure isomers, their Nb'-oxides and their addition salts with a pharmaceutically acceptable inorganic or organic acid. 
<??>These compounds are antitumoral agents.
Patent AU-2597592-A (AU)
Title: Injection needle arrangement
IPC: A61M5/32
Filed: 1992-08-31
Abstract: PCT No. PCT/SE92/00596 Sec. 371 Date May 3, 1993 Sec. 102(e) Date May 3, 1993 PCT Filed Aug. 31, 1992 PCT Pub. No. WO93/05835 PCT Pub. Date Apr. 1, 1993.A device for limiting the penetration of an injection needle when an injection is administered from an injection apparatus comprises an exterior sleeve (1) arranged around the front part of the injection apparatus (2). In its foremost position, the sleeve (1) surrounds the needle (8) completely, and it may be displaced rearwards while overcoming a spring force (6), to expose the needle (8).
Patent AU-2788997-A (AU)
Title: Large-sized columnar body of fiber-reinforced plastic
Inventor: KITANO AKIHIKO
IPC: B32B17/04
Filed: 1997-05-15
Abstract: A large-sized columnar body which is formed out of a fiber-reinforced plastic comprising continuous fibers and a resin, and which has three layers (A, B, C) laid in the mentioned order, characterized in that the reinforcing fiber in the B layer is carbon fiber arranged in the lengthwise direction of the columnar body, the fiber in the A layer and C layer being carbon fiber or/and glass fiber arranged at +/-50 to +/-70 degrees with respect to the lengthwise direction of the columnar body. This large-sized columnar body of FRP has a high compressive strength, so that the weight thereof can reduced to below that of a conventional large-sized columnar body. Accordingly, this columnar body is suitable as a primary structural material used as a building material, and for structures, aircrafts and ships. <IMAGE>
Patent AU-2972200-A (AU)
Title: Short aggregate pier techniques
Inventor: FOX NATHANIEL S
IPC: E02D5/34
Filed: 2000-01-25
Abstract: Methods for augmenting the load bearing characteristics of short aggregate piers include preloading matrix soils, adding chemical additives to matrix soils and using mesh reinforcement in matrix soils and in cooperation with the aggregate lifts associated with pier constructions. Methods for expanding the feasibility of short aggregate piers include the use of gradations of aggregate, reducing friction between the short aggregate pier and adjacent matrix soils using liners or lubricating materials, controlling liquefaction by employing aggregate drains in short aggregate pier constructions, the use of non-impact forces alone or in conjunction with vibratory forces in construction short aggregate pier lifts, and the use of indigenous materials in short aggregate pier constructions. Other methods for augmenting the construction of short aggregate piers include the use of variable dimensioned lifts, the use of interlocking aggregates and recycled materials, such as recycled concrete, the use of temporary casings to protect pier cavities, and the use of load sensors to monitor stresses within short aggregate pier constructions and pressure cells to measure load/deformation characteristics. The invention also includes systems for lateral load stabilization and uplift anchoring utilizes short aggregate pier construction techniques; systems to apply preload to short aggregate piers to increase their stiffness. The invention also includes an apparatus for applying preload to short aggregate pier and matrix soils and other constructions incorporates a pair of half shells operatively associated with an actuator for moving them outward. Once inserted into the pier cavity, the half shells are forced outward to apply preload forces to the pier cavity walls and matrix soil.
Patent AU-3113795-A (AU)
Title: Stair component
Inventor: JUNG HORST
IPC: E04F11/16
Filed: 1995-07-18
Abstract: The invention relates to a stair component (16) for renovating an overhanging step (10) with a tread (12) and a riser (14) comprising a single or multi-part cladding (18, 28, 42) covering the tread and riser with a section (28) running along the riser and covering it at least partly. To facilitate renovation using structurally simple means with easy matching to steps of differing height, it is proposed that the longitudinal edge (30) running parallel to the step (10) section (28) covering the riser (14) in sections terminate at a distance from the underside (48) of the overhanging stair and an L-shaped bent finishing component (42) with an arm (46) (transverse arm) extending as far as beneath the step extend from the longitudinal edge.
Patent AU-3145899-A (AU)
Title: Wiping-off screen
Inventor: NIKLAS HERMANN
IPC: B44D3/12
Filed: 1999-03-17
Abstract: The invention relates to a screen (1) for wiping off paint, for a container (2). The wiping-off screen can be securely and permanently fitted to said container (2), hereby facilitating painting work. According to the invention, a bracket (3) of the wiping-off screen (1) latches onto an edge (6) of the container (2). This causes a screen element (4) of the wiping-off screen (1) to be pressed against an inner wall (9) of the container (2), with the result that the wiping-off screen (1) is securely positioned on the container (2).
Patent AU-3165495-A (AU)
Title: Method of producing o-(2-hydroxyalkyl)-oximes
Inventor: HARREUS ALBRECHT
IPC: C07C249/12
Filed: 1995-07-25
Abstract: PCT No. PCT/EP95/02932 Sec. 371 Date Feb. 3, 1997 Sec. 102(e) Date Feb. 3, 1997 PCT Filed Jul. 25, 1995 PCT Pub. No. WO96/04237 PCT Pub. Date Feb. 15, 1996Preparation of O-(2-hydroxyalkyl)oximes I    <IMAGE>  (I)  (R1 and R2=alkyl or R1 and R2 and the C atom which carries them=5- to 7-membered cycloalkyl), by catalytically hydrogenating an O-(2,3-epoxyalkyl)oxime of the general formula II    <IMAGE>  (II)  using hydrogen. The products I are suitable as intermediates for herbicides.
Patent AU-3260101-A (AU)
Title: Novel use of phenylheteroalkylamine derivatives
Inventor: CHESHIRE DAVID
IPC: C07C319/14
Filed: 2001-02-20
Abstract: There is disclosed the use of a compound of formula (I), wherein R<SUP>1</SUP>, R<SUP>2</SUP>, X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts, enantiomers or racemates thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of nitric oxide synthase activity is beneficial. Certain novel compounds of formula (Ia) and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof are disclosed; together with processes for their preparation, compositions containing them and their use in therapy. The compounds of formulae (I) and (Ia) are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment or prohylaxis of inflammatory disease
Patent AU-3262599-A (AU)
Title: Chemical compounds and their use to elevate pyruvate dehydrogenase activity
Inventor: BUTLIN ROGER JOHN
IPC: A61K31/167
Filed: 1999-03-02
Abstract: The use of a compound of the formula (I):wherein: ring C is phenyl or carbon-linked heteroaryl selected from pyridyl, pyrazinyl, pyrimidinyl and pyridazinyl; and wherein said phenyl or heteroaryl is substituted as defined herein; A-B is selected from NHCO, OCH2, SCH2, NHCH2, trans-vinylene, and ethynylene; R1 is linked to ring C at a carbon ortho to the position of A-B attachment and is defined herein; n is 1 or 2; R2 and R3 are alkyl, haloalkyl or together from cycloalkyl or halocycloalkyl as defined herein; in the manufacture of a medicament for use in the elevation of PDH activity in warm-blooded animals such as humans is described. Salts and esters of compounds of formula (I) are also described.
Patent AU-3451700-A (AU)
Title: Pharmaceutical compositions comprising cyclic glycerophosphates and analogs thereof for promoting neural cell differentiation
Inventor: SHINITZKY MEIR
IPC: A61P25/28
Filed: 2000-03-24
Abstract: Cyclic glycerophosphates and analogs thereof (CGs) are shown to exert neutral promoting activities in target cells. Such activities include promotion of neuronal outgrowth, promotion of nerve growth, provision of dopaminotrophic supporting envrionment in a diseased portion of the brain, prevention of nerve degeneration and nerve rescue. These activities of the CGs render them useful for treatment of various disorders including but not limited to mental disorders such as, for example, schizophrenia, dementia or disorders resulting in learning disablities. In addition, these CGs may be used for the treatment of neurodegenerative conditions such as Altzheimer's diesease, Parkinson's disease, conditions resulting from exposure to harmful environmental factors or resulting from a mechanical injury. The CGs may also be used to treat an individual suffering from a primary neurodengenerative condition in order to prevent or reduce the appearance of secondary degeneration in additional nerves ("nerve rescue").
Patent AU-3536597-A (AU)
Title: Device for holding re-usable materials
Inventor: SCHUSTER CHRISTOPH
IPC: A47C13/00
Filed: 1997-06-25
Abstract: The invention concerns a device for holding re-usable materials which comprises a plurality of receptacles for different re-usable materials disposed in a housing (19), which is of a step-like design (16, 17, 18), the lids (26, 28, 29) which allow access to the receptacles simultaneously acting as a tread.
Patent AU-3738199-A (AU)
Title: Method and apparatus for preparing food products for further processing
Inventor: HYLLSTAM MARI
IPC: A23L5/10
Filed: 1999-04-01
Abstract: In a method of preparing soft or sticky food products for further processing, the food products are heated from below for setting a surface layer of the food products which forms a crust holding and supporting the food products during further processing. An apparatus for performing this method comprises a belt conveyor having a conveyor belt for conveying the soft or sticky food products along a path upstream of the further processing, and heating element positioned below and on both sides of the conveyor belt in the path upstream of the further processing. The heating elements heat the soft or sticky food products on the conveyor belt from below and laterally for forming a crust which is able to hold and support the food products during the further processing.