baber/WOPTO huggingface dataset:
Patent EP-0630905-B1 (EP)
Inventor: CHOU TA-SEN
IPC: C07H19/167
Filed: 1988-08-22
Granted: 1999-05-06
Abstract: The present invention provides a process for preparing lactone intermediates to 2',2'-difluoronucleosides whereby reversion back to the lactone's open chain precursor is minimized and the desired erythro enantiomer can be selectively isolated from an enantiomeric mixture of erythro and threo lactones in crystalline form. Also provided is a process for producing 2'-deoxy-2',2'-difluoronucleosides in about a 1:1 α/β anomeric ratio, and processes for selectively isolating β-2'-deoxy-2',2'-difluorocytidine, or an organic or inorganic acid addition salt thereof, from the 1:1 α/β mixture.
Patent EP-0629937-B1 (EP)
Inventor: LHOMER GERARD
IPC: F16K1/30
Filed: 1994-06-02
Granted: 1998-07-29
Abstract: The valve fitting for controlling distribution of gas includes a lower block (1) which is mounted on the gas cylinder (4). This includes a manometer (9) and a filling connector (11). Above this there is a sub-assembly (32,17) which is axially displaceable in response to the rotation of a tubular control which surrounds the sub-assembly. The sub-assembly includes an expansion valve (27) and an indexable flow regulator (34,35). The sub-assembly provides both a low pressure outlet (45) and a medium pressure outlet (51).
Patent EP-0650996-B1 (EP)
Inventor: COTEVIEILLE DENIS
IPC: C08G73/00
Filed: 1994-10-26
Granted: 1999-11-17
Abstract: Process for the manufacture of copolymers with magnetic properties, including a first stage of copolymerisation by oxidation in acidic medium of a first monomer chosen from optionally substituted aniline and of a second monomer chosen from substituted aminoaromatic compounds, which comprises:   - an induction stage during which the first monomer is brought into contact with at least one oxidising agent and at least one initiating agent, - and a production stage during which, after the introduction of the second monomer, at least one oxidising agent and at least one initiating agent are gradually added.
Patent EP-0650456-B1 (EP)
Inventor: SKOW LYNN R
IPC: B65G51/03
Filed: 1993-06-29
Granted: 1996-12-11
Abstract: L'appareil (10) décrit, qui permet de maintenir et travailler sur un article (8), comprend un élément (12) doté d'une surface de travail (14) et des orifices à fluide (18) qui traversent ledit élément (12) et se terminent par des sorties (22) sur la surface de travail (14). L'élément (12) se présente sous la forme d'une bande formée d'une pluralité de couches empilées (38). Un fluide dirigé sur la surface de travail (14) à travers les orifices (18) agit sur les articles (8) placés à proximité immédiate de la surface de travail (14).
Patent EP-0687306-B1 (EP)
Inventor: GODFROID EDMOND
IPC: C12Q1/689
Filed: 1994-02-18
Granted: 2000-12-06
Abstract: PCT No. PCT/BE94/00012 Sec. 371 Date Aug. 21, 1995 Sec. 102(e) Date Aug. 21, 1995 PCT Filed Feb. 18, 1994 PCT Pub. No. WO94/19488 PCT Pub. Date Sep. 1, 1994The invention relates to an oligonucleotide agent suited to use in evidencing at least one strain of Borrelia burgdorferi. Proposed are sequences common to all the groups of Borrelia burgdorferi strains, suited to use either as primers during genetic amplification reactions, or as capture probes in a hybridization test on a solid support on which the target DNA is "sandwiched" between the said capture probe and a disclosure probe, or else as disclosure probes in the said hybridization test on a solid support. Also proposed are sequences specific to each of the groups of Bb strains, suited to use as primers during genetic amplification reactions or as disclosure or capture probes in the hybridization test on the solid support mentioned above.
Patent EP-0693199-B1 (EP)
Inventor: DEVITO RAYMOND P
IPC: G06T5/00
Filed: 1994-02-14
Granted: 1998-07-01
Abstract: On identifie automatiquement le grand axe du ventricule gauche par l'identification et la mise en corrélation des minima et des maxima dans des images de coupes du ventricule gauche. On identifie initialement le ventricule gauche dans une coupe transversale représentative du ventricule gauche. On calcule automatiquement et on utilise la ligne centrale de cette coupe en tant qu'axe de réorientation le long duquel on reconstruit une autre coupe (sagittale) du ventricule gauche. On calcule automatiquement la ligne centrale de cette coupe sagittale qui correspond au grand axe du ventricule gauche. On confirme ensuite la précision de cette identification en reconstruisant les coupes transversales olbiques du ventricule gauche et en vérifiant que leurs centres coïncident.
Patent EP-0701644-B1 (EP)
Inventor: CLARK KENNETH GEORGE
IPC: E03B3/03
Filed: 1994-04-29
Granted: 2001-09-19
Abstract: The invention provides apparatus for use in collecting potable rainwater including: a trough member (10) having a dished surface (11) and adapted to receive rainwater when operatively disposed; a discharge outlet (12) in said trough member (10) in that part thereof (13) which is lowermost or near lowermost when the trough member is operatively disposed; delivery tube means (15) connected to said discharge outlet (12) for conveying received rainwater for passage to storage or distribution means; mounting frame means (18) whereby said trough member (10) may be mounted in a rain-receiving location, and tilt means (22) operatively connecting said trough member (10) to said mounting frame means (18); the parts being so made and arranged that said tilt means (22) will enable said trough member (10) to be moved between said operative disposition in which rainwater is received and then delivered via said discharge outlet (12) and said delivery tube means (15) and an inoperative disposition in which it has been tilted from said operative disposition to one of such inverted, semi-inverted or inclined nature that said dished trough surface (11) will not support liquid or solid materials.
Patent EP-0698076-B1 (EP)
Inventor: MENGAL PHILIPPE
IPC: C11B1/10
Filed: 1994-05-10
Granted: 1998-01-14
Abstract: The microwave extraction method involves the steps of placing the biological material in an enclosure without any solvent whatsoever and exposing it to microwave radiation to free at least some of the natural product, and then separating the residual biological material from the extracted natural product. Additionally, it involves the steps of applying reduced pressure in said enclosure during said microwave radiation stage and heating the enclosure during at least most of the microwave radiation stage to compensate the temperature drop resulting from water evaporation from the biological material.
Patent EP-0700440-B1 (EP)
Title: Regulator of contact-mediated hemolysin
Inventor: KING C HAROLD
IPC: A61P31/04
Filed: 1994-05-24
Granted: 1999-02-24
Abstract: PCT No. PCT/US94/05869 Sec. 371 Date Jun. 26, 1996 Sec. 102(e) Date Jun. 26, 1996 PCT Filed May 24, 1994 PCT Pub. No. WO94/28137 PCT Pub. Date Dec. 8, 1994The present invention relates to a nucleic acid that encodes a hemolysin protein and to a nucleic acid that encodes a positive regulator of hemolysis. The nucleic acid can be the basis of a vaccine against tuberculosis. The nucleic acid can be inserted into an avirulent vaccine strain such as M. bovis BCG.
Patent EP-0804246-B1 (EP)
Inventor: SCHACHT ETIENNE HONORE
IPC: A61K47/48
Filed: 1994-08-17
Granted: 2000-05-17
Abstract: PCT No. PCT/IB94/00259 Sec. 371 Date Feb. 20, 1996 Sec. 102(e) Date Feb. 20, 1996 PCT Filed Aug. 17, 1994 PCT Pub. No. WO95/05200 PCT Pub. Date Feb. 23, 1995A conjugate of a carrier polymer and aziridine ring containing mitomycin (MMC) drug molecules is prepared by coupling the MMC molecules via their aziridine imino groups to spacer groups that terminate in protected amino groups, deprotecting said amino groups, recovering and purifying the spacer-MMC derivatives, and then coupling these derivatives via said deprotected amino groups to the carrier polymer. Alternatively, the MMC may first be treated with an activating agent, e.g. carbodiimidazole, to form an activated MMC derivative which is then coupled directly to spacer groups linked to the carrier polymer.
Patent EP-0774943-B1 (EP)
Inventor: ASHTON GREGORY
IPC: A61F13/15
Filed: 1994-07-20
Granted: 2000-05-17
Abstract: Disclosed is an absorbent article having a liquid pervious topsheet, a liquid impervious backsheet joined to the topsheet, and an absorbent core positioned therebetween, in which the absorbent core is enveloped by a primary core integrity layer comprising a continuous mesh of strands of thermoplastic material which is joined to the topsheet and/or the backsheet. The primary core integrity layer is particularly useful for improving the wet integrity of absorbent cores comprising an upper acquisition/distribution layer and a lower storage layer.
Patent EP-0754040-B1 (EP)
Inventor: LUENGO JUAN IGNACIO
IPC: A61P13/02
Filed: 1994-08-02
Granted: 2003-02-26
Abstract: On décrit des dérivés de la rapamycine, des compositions pharmaceutiques contenant ces dérivés de la rapamycine et des vecteurs ou excipients acceptables au plan pharmaceutique, ainsi que des méthodes d'utilisation de ces dérivés pour inhiber la croissance des champignons pathogènes, pour inhiber l'immuno-suppression ou pour traiter les tumeurs carcinogènes.
Patent EP-0712396-B1 (EP)
Inventor: KRUEGER BERND-WIELAND
IPC: C07D273/01
Filed: 1994-07-29
Granted: 1998-11-04
Abstract: PCT No. PCT/EP94/02533 Sec. 371 Date Feb. 5, 1996 Sec. 102(e) Date Feb. 5, 1996 PCT Filed Jul. 29, 1994 PCT Pub. No. WO95/04728 PCT Pub. Date Feb. 16, 1995The application relates to new azadioxacycloalkenes of the formula (I)    <IMAGE>  (I)  in which Z, G, Ar, E and A have the meaning given in the description, to a process for their preparation, and to their use as fungicides.
Patent EP-0686441-B1 (EP)
Inventor: KATO AKIRA
IPC: B21D39/02
Filed: 1994-10-06
Granted: 2000-02-23
Abstract: To provide a joining and uniting means which does not cause two metal plate materials, which are to be joined into a unitary structure by curling, to become out of alignment when they are put together, and which does not, moreover, require an operation for aligning a projection or a cut and raised portion and a hole with each other, a projection (11) is formed on an end portion (21) of one metal plate material (5), and this projection (11) is pushed forcibly into an end portion (22) of the other metal plate material (9, 10), whereby two metal plate materials are joined into a unitary structure.
Patent EP-0690174-B1 (EP)
Inventor: SASSI IVES
IPC: E01C23/088
Filed: 1995-06-12
Granted: 2001-08-22
Abstract: The implement is intended to be coupled to a motor-driven towing vehicle and comprises a roller-cutter (10) of substantially horizontal axis, to the cylindrical surface of which there is fixed a plurality of tools (11) able to crush and shift the ground (A) to be treated; means for rotating said roller-cutter about its axis are also provided, as are means for supporting the roller-cutter (10) arranged with its axis substantially perpendicular to or possibly inclined to the direction of advancement and for maintaining the lower surface of the roller-cutter (10) at the required depth below the surface of the ground to be treated; finally, means are provided for distributing the material crushed by the roller-cutter (10) in such a manner as to fill any recesses and flatten any projections. <MATH>
Patent EP-0710936-B1 (EP)
Inventor: KOOIJ HERMAN
IPC: G07F11/62
Filed: 1995-10-31
Granted: 1998-05-13
Abstract: A retail furnishing for cut flowers has a cooled housing in which a turret with holders is arranged. Each holder has a plurality of compartments placed one above another which are each provided with a reservoir for water for the flowers. The purchaser can bring the desired compartment behind a removal opening by operating keys. The removal opening can be unlocked by inserting coins of appropriate value. Because only one compartment is accessible, the possibility of fraud is excluded. <IMAGE>
Patent EP-0788688-B1 (EP)
Inventor: TSUDIK GENE
IPC: G06F21/34
Filed: 1994-10-27
Granted: 2004-01-21
Abstract: A method and an apparatus are provided for securely identifying a mobile user while avoiding trackability of his/her movements, i.e. it provides a way for a secure user identification in secrecy. The gist is to encrypt the user's identifier, and/or his/her password, and a synchronization indication, preferably a fixed time interval, under a secret one-way function and sending the encrypted message, called a "dynamic user identifier", to the user's "home authority" where he/she is registered. The home authority comprises correspondence tables listing, pre-computed for every time interval (or another chosen synchronization), the dynamic user identifiers and the corresponding true identity of the user and can thus quickly decide whether the received encrypted message originates from a registered user. On the other hand, an intruder is neither able to detect from the encrypted messages the identity of the user nor can he/she track a user's moves.
Patent EP-0731636-B1 (EP)
Inventor: KIEFER MICHAEL C
IPC: C12N15/12
Filed: 1994-11-30
Granted: 2006-01-11
Abstract: The present invention provides a novel family of apoptosis-modulating proteins. Nucleotide and amino acid residue sequences and methods of use thereof are also provided.
Patent EP-0741619-B1 (EP)
Inventor: PLESCHIUTSCHNIGG FRITZ-PETER
IPC: B22D11/128
Filed: 1995-01-19
Granted: 2000-09-27
Abstract: PCT No. PCT/DE95/00096 Sec. 371 Date Jul. 29, 1996 Sec. 102(e) Date Jul. 29, 1996 PCT Filed Jan. 19, 1995 PCT Pub. No. WO95/20447 PCT Pub. Date Aug. 3, 1995A continuous casting device comprises, in combination, a continuous casting mold for receiving molten metal, and at least one pair of guide rolls disposed immediately downstream of the mold exit opening. The exit opening of the mold is rectangular shaped so as to permit a rectangular strand to be cast which has a liquid core, a width and a thickness. The guide rolls are constructed so as to impart to the rectangular strand leaving the mold exit opening a convex shape so as to prevent snaking of the strand within the continuous casting device. The convexivity concavity extends along at least a part of the width of the strand and is no more than 8% of the strand thickness.
Patent EP-0812838-B1 (EP)
Inventor: SAKAMOTO MASATO
IPC: B01D53/14
Filed: 1995-02-02
Granted: 2002-05-02
Abstract: This invention relates to bicyclic amino group-substituted pyridonecarboxylic acid derivatives of the general formula A-Pri, esters thereof and salts thereof, wherein:     Pri is a pyridonecarboxylic acid residue, and A is a bicyclic amino group represented by the following formula and joined to the 7-position of the pyridonecarboxylic acid or a position equivalent to the 7-position thereof.   <CHEM> wherein R1 and R2 may be the same or different and each represents a hydrogen atom, a lower alkyl group or an amino-protecting group; R3 and R4 may be the same or different and each represents a hydrogen atom, a halogen atom, a cyano group, a hydroxyl group, an oxo group, a lower alkoxy group or a lower alkyl group; and n is an integer of 0 or 1. The above-described pyridonecarboxylic acid derivatives, esters thereof and salts thereof are useful as antibacterial agents. This invention also relates to bicyclic amine compounds useful as direct intermediates for the synthesis of the above-described pyridonecarboxylic acid derivatives.
Patent EP-0741644-B1 (EP)
Inventor: LOVIN JOSEPH R
IPC: B41F5/24
Filed: 1995-01-24
Granted: 1998-10-28
Abstract: A system and method for the printing of substrates for use in food packaging and, more particularly, a flexographic printing system and method for applying and curing radiation cured inks to a flexible, heat shrinking web employing a combination of UV radiation and EB radiation.
Patent EP-0755611-B1 (EP)
Inventor: VAN GESTEL WILHELMUS JACOBUS
IPC: H04N9/82
Filed: 1995-03-29
Granted: 1999-11-03
Abstract: A recording arrangement is provided for recording trick mode information in portions of tracks, so as to enable a trick mode during reproduction in a reproducing arrangement. The recording arrangement comprises an input terminal (11) for receiving the digital video signal, a trick play signal generating unit (80) for deriving a trick play signal from the digital video signal, and an error correction encoding unit (26,28,81). The error correction encoding unit is adapted to carry out an error correction encoding step on the digital video signal and the trick play signal, such that an additional error correction encoding step is carried out on the trick play data. <IMAGE>   <IMAGE>
Patent EP-0756477-B1 (EP)
Inventor: ANDERSON R ROX
IPC: A61Q19/04
Filed: 1995-03-13
Granted: 2003-11-19
Abstract: Method for treating a proliferative skin disorder, such as psoriasis, in a human patient having affected and non-affected areas of skin. The method comprises the steps of: (1) topically applying a sunscreen providing photo-protection to the affected and non-affected areas of skin; (2) waiting for a time period sufficient for the skin of the affected areas to be substantially sloughed off; and, (3) exposing the affected and non-affected areas of skin of the patient to a selected level of optical radiation. The level of radiation is chosen to be sufficient to treat the affected areas of skin and insufficient to cause significant damage to the non-affected areas of skin. The method enhances effectiveness and safety of treatment by providing preferential photo-protection to the non-affected skin areas, and may be used for phototherapy, photochemotherapy, or photodynamic therapy.
Patent EP-0758284-B1 (EP)
Inventor: GOODWATER FRANK
IPC: B23P11/02
Filed: 1995-03-20
Granted: 2002-08-28
Abstract: A process and apparatus are provided for separating components of a brazed vane assembly by preheating the assembly to a temperature below the solidus of the base metal of the vane assembly and above the liquidus of the braze, then maintaining such temperature while separating the airfoil from the platform by pulling/pushing the airfoil and platform apart.
Patent EP-0778747-B1 (EP)
Inventor: BAEKGAARD KNUD ERIK
IPC: A61B7/04
Filed: 1995-08-30
Granted: 2006-03-22
Abstract: PCT No. PCT/DK95/00349 Sec. 371 Date Feb. 28, 1997 Sec. 102(e) Date Feb. 28, 1997 PCT Filed Aug. 30, 1995 PCT Pub. No. WO96/06562 PCT Pub. Date Mar. 7, 1996An electronic stethoscope consisting of a transducer, an amplifier and a headphone will be better adapted to the habits of use of doctors when it is supplied with filters which mimic the transfer function of acoustic stethoscopes. Thus, the signals heard will correspond to those learnt, and thereby the advantages of greater amplification and elimination of noise sources may be fully utilized. Hence there is a possibility for extended digital signal processing which may furthermore compensate for the hearing loss of each individual doctor.
Patent EP-0779972-B1 (EP)
Inventor: MUELLER ROLAND
IPC: G01M17/04
Filed: 1995-09-11
Granted: 1999-12-08
Abstract: In known devices for testing vehicle shock absorbers, the tires, which have a dampening effect, are not taken into account, so that the measurement results may be falsified by up to about 30%, depending on the tire pressure. In addition, when the wheels are mounted on the vehicle, no shock absorber characteristic curve may be measured, only individual values. In the disclosed device, the actuating variable "tire" is eliminated by a regulation process that consists in normalizing the resonance amplitude, a considerably more accurate measurement being thus obtained. In addition, the spring constant of the wheel suspension is determined before actually testing the shock absorbers, allowing defective springs to be detected. Finally, car body oscillations may also be determined, causing an additional precision gain. For the first time it becomes possible to determine a shock absorber characteristic curve without having to dismount the shock absorbers.
Patent EP-0788366-B1 (EP)
Inventor: AGRAWAL SUDHIR
IPC: A61P35/00
Filed: 1995-10-17
Granted: 1999-12-15
Abstract: Disclosed is a method of down-regulating the expression of a gene in an animal, wherein a pharmalogical formulation comprising an oligonucleotide complementary to the gene is orally administered to an animal. The oligonucleotide administered has non-phosphodiester internucleotide linkages and includes at least one 2'-substituted ribonucleotide, the oligonucleotide inhibiting the expression of a product of the gene, thereby down-regulating the expression of the gene.
Patent EP-0794913-B1 (EP)
Inventor: KORHONEN ANTTI
IPC: B65G1/00
Filed: 1995-12-21
Granted: 2003-05-28
Abstract: PCT No. PCT/FI95/00699 Sec. 371 Date Aug. 25, 1997 Sec. 102(e) Date Aug. 25, 1997 PCT Filed Dec. 21, 1995 PCT Pub. No. WO96/20121 PCT Pub. Date Jul. 4, 1996The invention relates to a method and apparatus for handling sheet stacks, in which sheet stacks including at least one sheet are moved into a storage area with the help of handling apparatuses into sheet piles of at least one sheet stack. By virtue of the support beds, a handling apparatus and a straddle carrier, and a flexible and efficient buffer storage system for sheet stacks are provided for interfacing with existing sheet processing lines.
Patent EP-0726053-B1 (EP)
Inventor: SCHMED ARTHUR-JOACHIM
IPC: A47J31/40
Filed: 1996-02-02
Granted: 1998-07-01
Abstract: The present invention relates to a method for preparing a beverage such as espresso coffee, which consists in: feeding pressurized hot water through a coffee powder tablet (10); blocking, downstream of the tablet (10), the extracted liquid that has passed through the tablet; producing a removable plug by means of said extracted liquid; causing an increase in pressure downstream of the tablet to increase the hot water pressurization inside the tablet; and reaching a removal pressure adapted to remove the removable plug, with subsequent dispensing of the extracted liquid at a dispensing pressure that is lower than the removal pressure to cause a decompression of the hot water inside the tablet (10). <IMAGE>
Patent EP-0732147-B1 (EP)
IPC: B05B1/12
Filed: 1996-02-28
Granted: 1999-05-12
Abstract: The shower has a change-over mechanism, to select the shower function. This has a slide (56) on the housing (1), moved translatory or rotary by a manual actuator (53). The slide can occupy three positions, corresponding to the shower functions. A first change-over element (37,63) is moved between two positions, by the slide, and via a guide and cam mechanism (61,62). The first position is for one function, the second position is for the remaining two functions. A second change-over element (45) is pressed by a spring (49) into one of two positions. In one slide position, a stop (59,60) on the slide retains the second change-over element in the first position, against the spring force. In a second slide position, the spring moves the element into its second position.
Patent EP-0719550-B1 (EP)
Inventor: GRIMFORS CHRISTER
IPC: A61L2/00
Filed: 1991-12-20
Granted: 2001-08-29
Abstract: The invention relates to the use of a compound according to formula (I) <CHEM>  in which X is an integer of from 2 to 5 and     A signifies - NH - C(=NH) - NH2 or - CH2 - NH2 for the preparation of a medicament for treatment of endotoxin-induced effects, particularly for suppressing endotoxin-induced pyrexia. The medicament is preferably administered orally, intravenously, intramuscularly, intracutaneously or intraperitoneally in an amount of 10-800 mg/kg body weight and hour.