Patent SG-11201808904S-A (SG)
Title: Personal dental care product for caries treatment
Inventor: HUG MICHAEL
IPC: C07K7/00
Filed: 2017-05-24
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD 1101/110 DOI 010111110101111 0 01 010 11010111 110110110111110 ill OEN Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\" WO 2017/202940 Al 30 November 2017 (30.11.2017) WIPO I PCT (51) International Patent Classification: PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, A61K 8/64 (2006.01) CO7K 7/00 (2006.01) SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, A61Q 11/00 (2006.01) A61K 38/04 (2006.01) TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. A61K 6/00 (2006.01) A61P 1/02 (2006.01) (84) Designated States (unless otherwise indicated, for every (21) International Application Number: kind of regional protection available): ARIPO (BW, GH, PCT/EP2017/062589 GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (22) International Filing Date: UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 24 May 2017 (24.05.2017) TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (25) Filing Language: English MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (26) Publication Language: English TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (30) Priority Data: 16171015.7 24 May 2016 (24.05.2016) EP Published: — (71) Applicant: CREDENTIS AG [CH/CH]; Dorfstrasse 69, with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) 5210 Windisch (CH). (72) Inventors: HUG, Michael; Rigiweg 11, 4800 Zofmgen (CH). LYSEK, Dominikus Amadeus; Miilligerstrasse 16t, 5210 Windisch (CH). (74) Agent: MORE, Solveig; Hinf Wife, TheatinerstraBe 16, 80333 Munich (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, = (54) Title: PERSONAL DENTAL CARE PRODUCT FOR CARIES TREATMENT Fig. liA B A A B ,-, © 7r 0\ el c:::: , (57) : The present invention provides new dental care products comprising self-assembling peptides that are capable of un- el dergoing self-assembly at a certain pH for use in dental care, e.g. preventing and/or treating a tooth lesion such as a caries lesion, remineralising a tooth surface or increasing smoothness or shine, or for increasing hardness of a tooth surface. The present invention Il provides dental care products such as chewing gum, toffees or toothpaste, in which the peptides are present in monomeric form for a © prolonged period after application into the oral cavity, thereby enabling non-targeted treatment of a plurality of teeth, independent of ei _ the diagnosis of an active lesion. Products of the invention are useful for animals and humans.