baber/WOPTO huggingface dataset:
Patent EP-1428822-B1 (EP)
Inventor: SONESSON CLAES
IPC: C07D295/096
Filed: 2000-12-22
Granted: 2010-12-15
Abstract: New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)-piperidine compounds of Formula 1:   
wherein X N, CH, or C, however X may only be C when the compound comprises a double bond at the dotted line; R 1  is OSO 2 CF 3 , OSO 2 CH 3 , SOR 3 , SO 2 R 3 , COR 3 , NO 2 , or CONHR 3  and when X is CH or C R 1  may also be CF 3 , CN, F, Cl, Br, or I; R 2  is a C 1 -C 4  alkyl, an allyl, CH 2 SCH 3 , CH 2 CH 2 OCH 3 , CH 2 CH 2 CH 2 F, CH 2 CF 3 , 3,3,3-trifluoropropyl, 4,4,4-trifluorobutyl, or -(CH 2 )-R 4 ; R 3  is a C 1 -C 3  alkyl, CF 3 , or N(R 2 ) 2 ; R 4  is a C 3 -C 6  cycloalkyl, 2-tetrahydrofurane or 3-tetra-hydrofurane, as well as pharmaceutically acceptable salts thereof are disclosed. 
Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed.
Patent EP-1363366-B1 (EP)
Inventor: SILLARD HELENE
IPC: H01S5/06
Filed: 2003-04-15
Granted: 2010-05-05
Abstract: The Bragg wavelength of the reflector (2) is adjusted in such a way that, for each selected operating wavelength (SEL), the derivative (dPr/dIa) of the power of the laser in relation to the current (Ia) injected into the amplifying section (I) of the laser (L) is maintained equal to the nominal for which the source has a rejection rate for the secondary modes which is close to the maximum value that the rate can reach for the selected wavelength.
Patent EP-1422175-B1 (EP)
Inventor: ADAMI MAURO
IPC: B65H19/18
Filed: 2003-09-24
Granted: 2008-08-20
Abstract: The splicing device comprises two heads (41A, 43A; 41 B, 43B), each of which has: a roller (33A; 33B) associated with a clamping bar (93A; 93B) to hold between said roller and said clamping bar an initial edge (L) of the second web material; a counter-pressure member (53A; 53B) cooperating with said roller to press said first and second web materials against each other; and a cutting member (67A; 67B). <IMAGE>
Patent EP-1583608-B1 (EP)
Inventor: VAN DER ZANDEN JOHANNES PETRUS
IPC: B02C13/18
Filed: 2003-03-12
Granted: 2006-06-14
Abstract: The method and the device according to the invention relates to a stator and an armoured ring which are combined to give a stationary annular collision member that is arranged around the rotor, as it were in the form of a stator that is provided all round along the inside, which faces the axis of rotation, with protruding collision surface reliefs, each of which is provided with at least one collision surface that is arranged transversely in the ejection stream that the material describes when it is propelled outwards from the rotor.
Patent EP-1493848-B1 (EP)
Inventor: OHTANI NOBORU
IPC: C30B29/36
Filed: 2003-03-31
Granted: 2010-12-08
Abstract: The present invention relates to a seed crystal consisting of a silicon carbide single crystal suitable for producing a substrate (wafer) for an electric power device, a high-frequency device or the like, and a method for producing an ingot using the same. A single crystal growing face of a seed crystal consisting of a silicon carbide single crystal is inclined at an angle ranging from 3 degrees or more to 60 degrees or less with respect to the (11-20) face to a direction inclined at an angle ranging from −45 degrees or more to 45 degrees or less from a <0001> direction to the [1-100] direction. By performing crystal growth using such a seed crystal, a high quality silicon carbide single crystal ingot can be obtained. According to the present invention, it is possible to obtain material consisting of a silicon carbide single crystal of favorable quality, which has few crystal defects such as micropipe defects and stacking faults, and the diameter is suitable for practical application.
Patent EP-1495038-B1 (EP)
Inventor: ASHE ARTHUR J III
IPC: C08F10/00
Filed: 2003-03-24
Granted: 2008-07-23
Abstract: L'invention concerne des complexes métalliques, des catalyseurs qui en sont dérivés et des processus de polymérisation utilisant lesdits complexes et catalyseurs précités. Lesdits complexes et catalyseurs se caractérisent par la présence d'un ou de plusieurs groupes de ligands cycliques à 5 chaînons, anioniques, contenant de l'azote et du bore, notamment des groupes de 1,2-azaborolyl.
Patent EP-1472426-B1 (EP)
Inventor: MAYER FRANK F E
IPC: E05C17/54
Filed: 2003-01-24
Granted: 2006-07-26
Abstract: The invention relates to a stop for doors and windows. Said stop consists of an elastic rubber body with a high friction coefficient, which has a thicker round region tapering to an adjacent narrow tip region. According to the invention, the narrow tip region is curved inwards and the width of the body is slightly larger than the distance between the perpendicular case of a window and its frame, the thickness of said body being proportioned in such a way that it can stand on its edge. A stop of this type is versatile for doors and windows and can hold windows at various open angles.
Patent EP-1545808-B1 (EP)
Title: Bending machine
Inventor: KUTSCHKER WOLFGANG
IPC: B21D5/04
Filed: 2003-06-26
Granted: 2007-05-02
Abstract: The bending machine (10) has an upper moveable clamp block (16) and a fixed lower block each having selected tool pieces attached by which the sheet material is clamped during bending by a drive motor (84) and shaft (80) turning worm gears and threaded rods (46,48) to move the lower block.
Patent EP-1509621-B1 (EP)
Inventor: CLERICI MARIO
IPC: C12Q1/6883
Filed: 2003-05-30
Granted: 2009-09-09
Abstract: An inflammatory process is suggested to be involved in the pathogenesis of Alzheimer's disease (AD), a neurodegenerative disorder characterized by the presence of neuritic plaques within the cerebral cortex that are mainly composed of a small insoluble protein of 40-42 aminoacids (amyloid protein). Amyloid-specific Interleukin-10 (IL-10) generation is found to be selectively and significantly reduced in AD patients (p=0.023). The genotype associated with high IL-10 production is extremely infrequent in AD individuals (2% vs. 28%). The presence of low/intermediate-IL-10-producing genotypes (GCC/ATA; ATA/ATA) was associated with an earlier age at disease onset and (ACC/ACC; ACC/ATA) with an accelerated rate of disease progression/severity and with amyloid-specific impairment of IL-10 production. This relationship is independent of ApoE gene polymorphism. These results support the use of anti-inflammatory compounds in the therapy of this disease.
Patent EP-1488523-B1 (EP)
Inventor: LEIJTEN-NOWAK KATARZYNA
IPC: H03K19/177
Filed: 2003-03-17
Granted: 2010-02-17
Abstract: A reconfigurable processing device comprises one or more reconfigurable processing units. At least one processing unit utilizes a computational unit having a preprocessing module for receiving n input signals, and s1 selection signals, and providing k output signals wherein k<n+s1. The computational unit further comprises an m-output look-up table being addressed by the k output signals of the preprocessing module and an output multiplexer for selecting one of the m output signals of the look-up table under control of s2 further selection signals.
Patent EP-1492513-B1 (EP)
Inventor: SCHMELZER CHRISTEL
IPC: A61K47/34
Filed: 2003-03-20
Granted: 2006-09-20
Abstract: Suspensions of crystalline tiotropium bromide monohydrate (I) in the propellant gases HFA 227 and/or HFA 134a, optionally mixed with one or more further propellant gases selected from propane, butane, pentane, dimethyl ether, difluoromonochloromethane, difluoromethane, isobutane, isopentane and/or neopentane, are new. ACTIVITY : Antiasthmatic; Antiinflammatory. MECHANISM OF ACTION : Anticholinergic.
Patent EP-1497287-B1 (EP)
Inventor: RENHOWE PAUL A
IPC: A61P35/00
Filed: 2003-04-04
Granted: 2010-11-24
Abstract: L'invention porte sur des composés organiques ayant les formules (I) et (II) dont les variables ont les valeurs définies dans le descriptif. L'invention porte également sur des médicaments comprenant un médicament anticancéreux sélectionné à partir de 5-FU ou CPT 11 et un composé de formule (I) ou de formule (II), un tautomère du composé, un sel du composé acceptable d'un point de vue pharmaceutique, ou un sel du tautomère acceptable d'un point de vue pharmaceutique utilisés dans le traitement avec un médicament anticancéreux sélectionné à partir de 5-FU ou CPT-11. Ces médicaments peuvent être utilisés dans le traitement du cancer. L'invention porte également sur l'utilisation d'un composé de formule (I) ou de formule (II), d'un tautomère du composé, d'un sel du composé acceptable d'un point de vue pharmaceutique, d'un sel du tautomère acceptable d'un point de vue pharmaceutique dans le traitement du cancer conjointement avec un médicament anticancéreux sélectionné à partir de 5-FU ou CPT-11 .
Patent EP-1558419-B1 (EP)
Inventor: MECKEL NATHAN K
IPC: A61B17/00
Filed: 2003-04-21
Granted: 2007-06-13
Abstract: A bone saw blade includes a blade body having a cutting section, a hub section and a shank located between the cutting section and the hub section. The blade body is first formed having a substantially uniform Rockwell hardness between approximately Rc 49 and Rc 63 throughout. Next, a cathodic arc process is used to coat the cutting section with a hard, wear-resistant metal nitride coating. During the coating process, ion impingement on the surface of the cutting section creates heat that beneficially anneals the cutting section. Significant annealing of the shank and hub section is prevented during the coating process by stacking the blade bodies together with blade blanks that are formed without cutting sections. The heat generated during coating is insufficient to raise the temperature of the large mass above the annealing temperature of the blade material. The resultant blade has a high strength shank and hub section.
Patent EP-1502116-B1 (EP)
Inventor: GARCIA ALPHONSE
IPC: G01N33/68
Filed: 2003-05-06
Granted: 2008-01-02
Abstract: The invention relates to methods for identifying novel PP1-interacting polypeptides and proteins, compounds which are able to inhibit the binding of PP1c to certain factors naturally interacting with it, especially proteins of the Bcl-2 family (such as Bcl-x L  and Bcl-w), and pharmaceutical compositions comprising the same. The invention is based on the identification of a new PP1- binding motif having the sequence FXX[RK]X[RK], wherein X is any amino acid.
Patent EP-1507488-B1 (EP)
Inventor: STIFTER JAN
IPC: A61F2/46
Filed: 2003-02-18
Granted: 2008-09-24
Abstract: Arrangement for ascertaining function-determining geometric parameters of a joint of a vertebrate, especially a hip or shoulder joint of a human being, in preparation for the installation of a joint replacement implant, especially a hip or shoulder socket or an associated stem implant, by means of an optical coordinate-measuring procedure, having a stereocamera or stereocamera arrangement for the spatial recording of optical transducer signals, a mobile multipoint transducer which is in the form of a movable sensor for sensing bony references in the joint region in order to determine the coordinates thereof, at least one bone-fixed multipoint transducer which is configured for rigid attachment, especially screwed or clamped attachment, (in a region sufficiently distant from the joint) to an extremity originating from the joint, especially close to the proximal end of a femur or a humerus, an interactive sequence controller for controlling the sequential registration and storage of a set of measurement point coordinates supplied by the mobile multipoint transducer and sets of measurement point coordinates recorded in a first plurality of positions of the bone-fixed multipoint transducer in a plurality of rotated positions of the extremity and their subsequent processing in accordance with a previously stored processing sequence, an evaluation unit for evaluating the sets of measurement point coordinates supplied by the multipoint transducers and recorded by the camera arrangement for the purpose of determining the geometric parameters, which comprises means for determining the transversal, vertical and sagittal body axes as well as means for carrying out an iterative procedure, especially an adjustment calculation in accordance with the least squares method, to determine the coordinates of the center of rotation of the joint, and an output unit, which is connected to the sequence controller and to the evaluation unit, for issuing manipulation proposals to an operating surgeon in accordance with the predetermined process sequence and in dependence upon the results of the determination of the geometric parameters, and for displaying the results of the evaluation.
Patent EP-1530521-B1 (EP)
Inventor: COUTIER CHARLES
IPC: B60D1/00
Filed: 2003-08-05
Granted: 2011-03-16
Abstract: The transport and handling truck for workshops has a frame (B) with a tow coupling (1) horizontally pivoted to one end with a bar having a coupling socket (3) at its free end for temporary connection to a tow ball (13). A hitch is fixed to the other end of the truck for a following truck. The socket can have a gravity operated catch (10).
Patent EP-1534208-B1 (EP)
Title: Fauteuil roulant, notamment fauteuil roulant électrique
Inventor: PELKA JOACHIM
IPC: A61G5/00
Filed: 2003-09-04
Granted: 2006-12-13
Abstract: L'invention concerne un fauteuil roulant, notamment un fauteuil roulant électrique, comportant les éléments suivants : un cadre (20), au moins une roue orientable (3) et deux roues non orientables (5), les roues étant en liaison avec le cadre (20) et montées avec un empattement (R) entre elles, ainsi qu'un siège (10) fixé au cadre (20) et doté d'un dossier (8). L'invention est caractérisée en ce que l'empattement (R) est réglable.
Patent EP-1676433-B1 (EP)
Inventor: LAAKKONEN PASI
IPC: B41M1/14
Filed: 2003-10-22
Granted: 2011-08-10
Abstract: A method in a diffractive color system that specifies visual color effects and/or target colors that are formed by mixing together two or more diffractively produced primary colors. The primary colors and the characteristics of the elementary gratings used in producing them are selected in such a manner that they produce the desired exact primary colors particularly in the application-specific lighting and by taking into account, when required, the color of the substrate material and/or other background separately. A diffractive color system implements the method. A diffractive component produces the mixed target color. A product contains one or more diffractive color effects.
Patent EP-1526772-B1 (EP)
Inventor: AMMERMANN EBERHARD
IPC: A01N47/12
Filed: 2003-06-30
Granted: 2006-12-20
Abstract: Fungicidal mixtures, comprising A) at least one valinamide derivative of the formula I in which R is halogen, and B) the compound of the formula II in a synergistically effective amount, methods for controlling harmful fungi using mixtures of the compounds I and II and the use of the compounds I and II for preparing such mixtures are described.
Patent EP-1539763-B1 (EP)
Title: Inhibiteurs de l'azaindole kinase
Inventor: BHIDE RAJEEV
IPC: A61P29/00
Filed: 2003-07-18
Granted: 2011-04-13
Abstract: La présente invention concerne des composés de formule I, et leurs sels pharmaceutiquement acceptables. Les composés de formule I inhibent l'activité de la tyrosine kinase de récepteurs de facteur de croissance, notamment VEGFR-2 et FGFR-1, ce qui leur confère une propriété anticancéreuse. Les composés de formule I se prêtent également au traitement d'autres maladies associées aux voies de transduction de signal fonctionnant à travers les récepteurs de facteur de croissance.
Patent EP-1523392-B1 (EP)
Inventor: RALL GERHARD
IPC: B23B31/20
Filed: 2003-07-09
Granted: 2006-05-10
Abstract: The invention relates to a clamping device (11) for tools, consisting of a clamping tubular part (12) and a clamping head part (29) containing a support element (50). Said support element (50) can be screwed to the tubular part (12) and maintains a connection between the head part and a coupling device (16) of the tubular part. Furthermore, the support element (50) ensures that the clamping jaws (31) of the head part (29) do not pivot away from each other when a tool is clamped.
Patent EP-1551505-B1 (EP)
Inventor: YOMTOV BARRY
IPC: A61N1/362
Filed: 2003-10-06
Granted: 2010-02-24
Abstract: Medical device and methods are provided for controlled drug delivery in a cardiac patient. The device includes an implantable drug delivery module comprising reservoirs containing a drug and a control means for selectively releasing an effective amount of drug from each reservoir; one or more electrodes or sensors for cardiac monitoring, stimulation, or both; and a microcontroller for controlling operational interaction of the drug delivery module and the cardiac electrode. The electrodes may comprise ECG monitoring, cardioversion, or cardiac pacing electrodes. A medical device also is provided for controlled delivery of drug to a patient having congestive heart failure, which includes an implantable drug delivery module comprising a natriuretic peptide and a release mechanism for selectively releasing a pharmaceutically effective amount of the natriuretic peptide into the patient; and a microcontroller for controlling the release mechanism, for example, in response to one or more monitored patient parameters.
Patent EP-1534419-B1 (EP)
Inventor: REICHSTEIN VOLKMAR
IPC: B01J8/24
Filed: 2003-08-05
Granted: 2008-11-12
Abstract: Process for performing reactions in a fluidized particle layer involves suctioning a medium to be inserted into the particle layer using a gaseous propellant medium operating according to the jet pump principle, mixing with the medium and inserting into the particle layer.  An Independent claim is also included for a fluidized bed reactor comprising a wind line (1) for the medium to be injected into the reactor. A nozzle (5) with an inlet (6) for a propellant medium and an outlet in a fluid connection with the reactor is provided. The suction opening of the nozzle is connected to a wind line (1).
Patent EP-1573643-B1 (EP)
Inventor: BREYTMAN ALEX
IPC: H04N5/232
Filed: 2003-12-17
Granted: 2009-08-19
Abstract: Actuator systems are provided for automatically focusing an optical image reader. Techniques are also provided which are applicable to the design of imaging engines and imaging lens systems associated with image readers of various types. More specifically, the present invention relates to lens guidance assemblies and actuator systems for automatically focusing an objective lens associated with an imaging system of an optical image reader. The optical image reader is preferably an optical code image reader for imaging optical codes, such as bar codes.
Patent EP-1585448-B1 (EP)
Inventor: MEUNIER ALAIN
IPC: A61B17/70
Filed: 2003-12-29
Granted: 2011-11-30
Abstract: L'invention concerne un ensemble de traitement de la dégénérescence d'un disque intervertébral lésé disposé entre deux vertèbres. L'ensemble de traitement comprend :  - des cellules (16) analogues ou non à celles du disque intervertébral et implantables dans ledit disque ; et - un implant intervertébral (10) comportant :  . une cale intervertébrale (12) destinée à être disposée entre lesdites vertèbres ; et . des moyens de fixation (14) de ladite cale sur lesdites vertèbres
Patent EP-1473041-B1 (EP)
Inventor: LORIA EMILE
IPC: A61K31/00
Filed: 2002-03-28
Granted: 2006-10-18
Abstract: Antiallergic compositions containing (i) an anti-histamine, (ii) a histamine synthesis inhibitor, and optionally (iii) an allergen or isolated nucleic acid molecule that has at least one polynucleotide sequence coding for the allergen, together with a pharmaceutical carrier. ACTIVITY : Antiallergic; Antiinflammatory; Antiasthmatic; Dermatological. MECHANISM OF ACTION : Prevention of the synthesis of Th2 cells from Th0 cells, thus blocking the synthesis of Interleukins 4 and 13.
Patent EP-1522359-B1 (EP)
Inventor: DE FRANCESCHI BRUNO
IPC: B23B5/16
Filed: 2004-09-16
Granted: 2007-06-27
Abstract: An apparatus for preparing the welding region on the outer surface of plastic pipes, comprising elements (11) for anchoring to a pipe (12); a threaded pivot (31) being coupled to the anchoring elements to perform a longitudinal, rotary and translational motion; supporting elements (32) for a tool (33) being jointly coupled to the threaded pivot (31), that can be arranged so as to interfere with, and remove material from, the outer surface of the pipe (12). The anchoring elements (11) comprise a central body (13) with longitudinal sliding guides (14) thereon for rod-like elements (15), which protrude partially from the central body (13), do not intersect each other, and support at ends (20) feet (21) for resting against the inner surface of the pipe (12). Respective racks (22) are provided longitudinally on the rod-like elements (15) and are kinematically connected to a common actuation gear system (23). <IMAGE>
Patent EP-1426389-B1 (EP)
Inventor: HEILMAN WILLIAM
IPC: C08F8/00
Filed: 1998-06-22
Granted: 2013-03-27
Abstract: A process for the production of a hydroisomerized hydrocarbon product of an ethylene-olefin polymer, comprising the steps of:  (a) polymerizing ethylene and a first olefin in the presence of a single-site catalyst comprising a compound of a transition metal of Group IVb of the Periodic Table and an aluminoxane to produce a precursor polymer; and (b) hydroisomerizing at least a portion of said precursor polymer to produce a hydroisomerized hydrocarbon product; a hydroisomerized hydrocarbon product produced by said process, wherein the bromine number of the hydroisomerized hydrocarbon product ranges from about 0.04 to about 1.5; and a lubricant oil comprising said hydroisomerized hydrocarbon product as the base oil and an effective amount of at least one oil additive.
Patent EP-1512639-B1 (EP)
Inventor: ALLEGRINI MAURIZIO
IPC: B65D51/28
Filed: 2004-08-04
Granted: 2006-09-06
Abstract: The container cap (1) comprises a body (2) presenting an inner side facing said container (4), an outer side and a chamber (7) presenting an access aperture (8) facing the outer side of the cap (1) and able to contain a product, so rendering it accessible from the outside.
Patent EP-1478062-B1 (EP)
Inventor: DANE C BRENT
IPC: H01S3/137
Filed: 2004-05-10
Granted: 2010-07-07
Abstract: A method of operating a laser to obtain an output pulse having a single wavelength, comprises inducing an intracavity loss into a laser resonator having an amount that prevents oscillation during a time that energy from the pump source is being stored in the gain medium. Gain is built up in the gain medium with energy from the pump source until formation of a single-frequency relaxation oscillation pulse in the resonator. Upon detection of the onset of the relaxation oscillation pulse, the intracavity loss is reduced, such as by Q-switching, so that the built-up gain stored in the gain medium is output from the resonator in the form of an output pulse at a single frequency. An electronically controllable output coupler is controlled to affect output pulse characteristics. The laser acts a master oscillator in a master oscillator power amplifier configuration. The laser is used for laser peening.
Patent EP-1550430-B1 (EP)
Inventor: DELACOUR MARIE-LAURE
IPC: A61Q1/02
Filed: 2004-12-14
Granted: 2009-05-06
Abstract: Solid composition comprises water, solid silicone rubber particles, fibers and a powder. An independent claim is also included for putting make-up on keratinic materials by applying a composition as above to the keratinic materials, especially skin.
Patent EP-1481899-B1 (EP)
Inventor: GIRO AMIGO EZEQUIEL
IPC: B31B50/16
Filed: 2004-04-30
Granted: 2007-09-05
Abstract: The machine has an expansion device including a core expander (7) with a vertical aperture (15). The aperture traverses the expander and connects two frontal faces (18) of a tubular mesh. A traction device dragging the frontal faces is provided with a bottom. The aperture permits the welding unit to drag the frontal faces and adjoining laminates through the expander to weld the frontal faces and laminates.