baber/WOPTO huggingface dataset:
Patent CA-2147172-A1 (CA)
Inventor: HORSTMANN MICHAEL
IPC: A61L15/00
Filed: 1993-10-27
Abstract: The invention relates to a transdermal therapeutic system containing the active agent 17-.beta.-estradiol and possibly other active agents with a layered structure from a substantially moisture and active agent-impermeable substrate, one or more matrix layers and, if there are no adhesive matrix layers, an adhesive layer, in which the concentration of the dissolved estradiol in all the matrix layers and in the adhesive layer if it exists is between its saturation concentration in the dry state and that in the wet state, by "dry state" being meant that the basic material is in equilibrium with a gas phase with a relative humidity of under 10% and by "wet state" being meant that the basic material is in equilibrium with a gas phase with a relative humidity of over 90%.
Patent CA-2147206-A1 (CA)
Title: Air filter for the intake air of an internal-combustion engine
Inventor: ERNST VOLKER
IPC: B01D46/52
Filed: 1995-04-18
Abstract: An air filter, particularly for the intake air of an internal-combustion engine is provided herein. The filter includes a housing, an air filter insert which is arranged in the housing, and a cover which closes off the housing. The air filter insert includes an essentially-rectangular cartridge having a surrounding seal. The entire seal has a uniform Shore A hardness in the range of from 7 to 25 and is clamped between the housing and the cover in such a manner that it separates an unfiltered air chamber within the filter from a filtered air chamber within the filter. The filter further includes at least one clamp for clamping the cover and the housing to each other, the clamp simultaneously securing the filter insert in the housing in such a manner that the cover directly contacts the housing only adjacent to each clamp. In addition, a clearance exists between the cover and the housing except adjacent each clamp. As a result, the cover no longer rests, as previously, on the housing over the whole length of the seal, but rests only in the area of the clamps.
Patent CA-2151207-A1 (CA)
Title: Back mounted beverage dispenser
Inventor: BEYER CURT
IPC: B67D1/06
Filed: 1995-06-07
Abstract: A back mounted beverage dispenser is described which includes a beverage tank having a sidewall, a bottom, an inlet and an outlet adjacent the bottom. A harness is secured to the beverage tank, such that the tank is mountable to a back of a vendor. A rigid conduit is pivotally mounted to the outlet for movement about a substantially horizontal axis between a substantially vertical stored position and a substantially horizontal dispensing position. Stop means is provided for limiting pivotal movement and maintaining the rigid conduit in the horizontal dispensing position. A dispensing head is positioned at a remote end of the rigid conduit. The dispensing head has at least one valve controlled dispensing nozzle. The valve is movable between an open and closed position such that when the rigid conduit is in the dispensing position and the valve is placed in the open position beverage flows by force of gravity out of the at least one dispensing nozzle .
Patent CA-2151635-A1 (CA)
Title: Antitumoral Compounds
Inventor: GRAVALOS DOLORES G
IPC: A61K31/42
Filed: 1995-06-13
Abstract: New antitumoral compounds are of formula (I):       (I) where R2, R3, R4, R5, R6, and R10 are the same or different and each represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms, a hydroxy group or an acyloxy group R-(C=O)-O- (where R-(C=O)- is an acyl group of 1 to 26 carbon atoms); provided that at least one of R2, R3, R4, R5, R6, and R10 is an acyloxy group R-(C=O)-O- (where R-(C=O)- is an acyl group of 1 to 26 carbon atoms) and further provided that at least one of R2, R3, R4, R5, R6, and R10 is an acyloxy group R-(C=O)-O- (where R-(C=O)- is an acyl group of 10 to 25 carbon atoms); with the exception of the tetraacetate of bengazole A and the tetraacetate of bengazole B. The lead to these compounds is provided by digonazole triacetate of formula (V), obtained from digonazole which may itself be extracted from Jaspis diaonoxea.         (V)
Patent CA-2151814-A1 (CA)
Title: Pulp and bleach reagent mixer and method
Inventor: CARLSMITH ALLAN L
IPC: B01F7/04
Filed: 1993-12-09
Abstract: A contacting apparatus (50) for providing intimate contact between pulp and a gaseous bleaching reagent has an elongate substantially cylindrical chamber (60) having an inside diameter proportional to a mixing capacity and an inlet (52) for pulp and for the carrier gas and the gaseous bleaching reagent; a rotatable shaft (54) extending through the chamber along an axial centerline of the chamber; provisions, mounted on the rotatable shaft, for radially tossing the pulp within successive transverse planes to maintain a substantially uniform distribution of pulp across the radial extent of the cylindrical chamber (60) with a minimum of axial mixing; and further provision for regulating gas flow through the inlet (52) to transport the pulp through the mixing apparatus, the flow being proportioned to provide a predetermined pulp residence time within the chamber as determined by dimensions of the chamber, rotation speed of the shaft, concentration of the bleaching agent, pulp consistency, and pulp production requirements.
Patent CA-2155013-A1 (CA)
Title: C2 taxane derivatives and pharmaceutical compositions containing them
Inventor: HOLTON ROBERT A
IPC: C07C233/46
Filed: 1994-01-28
Abstract: Taxane derivatives having alternative C2 substituent which is -OCOR31 wherein R31 is substituted phenyl and the substituent is selected from the group consisting of alkanoxy, protected hydroxy, halogen, alkyl, aryl, alkenyl, acyl, acyloxy, nitro, amino and amido.        The taxane derivatives have the form of   wherein X1 is -OX6, -SX7, or -NX8X9; X2 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl; X3 and X4 are independently hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl; X5 is -COX10, or -SO2X11; X6 is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, or hydroxy protecting group; X7 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, or sulfhydryl protecting group; X8 is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterosubstituted alkyl, alkenyl, alkynyl, aryl or heteroaryl; X9 is an amino protecting group; X10 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, t-butoxy or heterosubstituted alkyl, alkenyl, alkynyl, aryl or heteroaryl; X11 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, -OX10, or -NX8X14; X14 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl; R1 is hydrogen, hydroxy, protected hydroxy or together with R14 forms a carbonate; R2 is -OCOR31; R2a is hydrogen; R4 is hydrogen, together with R4a forms an oxo, oxirane or methylene, or together with R5a and the carbon atoms to which they are attached form an oxetane ring; R4a is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cyano, hydroxy, -OCOR30, or together with R4 forms an oxo, oxirane or methylene; R5 is hydrogen or together with R5a forms an oxo, R5a is hydrogen, hydroxy, protected hydroxy, acyloxy, together with R5 forms an oxo, or together with R4 and the carbon atoms to which they are attached form an oxetane ring; R6 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl, hydroxy, protected hydroxy or together with R6a forms an oxo; R6a is hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl, hydroxy, protected hydroxy or together with R6 forms an oxo;      R7 is hydrogen or together with R7a forms an oxo, R7a is halogen, hydroxy, or together with R7 forms an oxo; R9 together with R9a forms an oxo; R9a together with R9 forms an oxo; R10 is hydrogen; R10a is -OCOR29, hydroxy, or protected hydroxy; R14 is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, hydroxy, protected hydroxy or together with R1 forms a carbonate; R14a is hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl; R29 and R30 are independently hydrogen, alkyl, alkenyl, alkynyl, monocyclic aryl or monocyclic heteroaryl; and R31 is substituted phenyl which is substituted with an alkyl, p-hydroxy, o-hydroxy, alkoxy, halogen, trifluoromethyl, protected hydroxy, aryl, alkenyl, acyl, acyloxy, nitro, amino, or amido substituent.      The taxane derivatives are antileukemia and antitumor agents.
Patent CA-2157767-A1 (CA)
Title: Genetically engineered enzymes and their conjugates for diagnostic assays
Inventor: BRATE ELAINE M
IPC: C12R1/19
Filed: 1994-03-09
Abstract: This invention relates to genetically enzymes, their ligand conjugates, their manufactures, and their use in qualitative or quantitative assays. A hybrid enzyme, such as an AP-epitope, has a foreign amino acid moiety (an epitope) inserted near the active site of the starting AP enzyme. The foreign amino acid moiety binds with an analyte, and, as a consequence of this binding, the enzymatic activity of the hybrid enzyme, AP-epitope, is modified. The changes in the enzymatic activity are dependent upon the presence, or the amount, of the analyte. In another embodiment, the hybrid enzyme consists of a cysteine introduced near the active site of an AP to give a hybrid enzyme. The cysteine on the hybrid enzyme serves as a point of conjugation of a ligand, such as theophylline, ferritin, thyroxine, or digoxigenin, to form the hybrid enzyme-ligand conjugate. The ligand binds with an antibody, an analyte or a binding molecule to an analyte and as a result of this binding, the enzymatic activity of the hybrid enzyme-ligand conjugate is modified or modulated.
Patent CA-2158049-A1 (CA)
Title: Adjustable rear sight assembly for a firearm
Inventor: EMERSON ASHLEY C
IPC: F41G1/28
Filed: 1995-01-12
Abstract: An adjustable rear sight (10) for a firearm, said firearm being of the type that has a front, a rear, a top, a bottom, a front sight, and right and left sides with a width therebetween, and the firearm having a frame and a barrel with a longitudinal axis. The firearm's top has a mounting groove that extends transversely across a major portion of the firearm for receiving a rear sight. The adjustable rear sight includes a rigid base (12) having a lower portion (16) and an upper portion (18). The lower portion (16) is shaped and sized to fit snuggly within the firearm's mounting groove. The base's upper portion (18) is shaped and sized to extend above the top of the firearm to provide the protection of a combat sight. The rear sight also has a central structural element (14) that is mounted for up and down movement with respect to the rigid base (12).
Patent CA-2158118-A1 (CA)
Title: Perforate diaphragm alignment system for spring brake actuators
Inventor: PLANTAN RONALD S
IPC: F15B15/10
Filed: 1995-09-12
Abstract: A diaphragm for spring brake actuators includes an aperture that receives a threaded securement member such that the diaphragm is directly fixed to a push rod. In this way, misalignment between the push rod and the diaphragm is eliminated. To overcome any leakage through the aperture the diaphragm is formed with sealing beads compressed by the securement member to achieve a seal. Preferably, diaphragm plates are received on each side of the diaphragm, and the sealing beads are compressed by the securement member to achieve a seal between the securement member and the diaphragm plates. An adequate seal is thus achieved, while still allowing the direct connection of the diaphragm to the push rod by a threaded connecting member. The diaphragm plate on the power spring side of the diaphragm extends upwardly into a recess in the power spring plate, and is in facial contact in an axial direction with a surface of the power spring plate when the spring is actuated. At the same time, there is a clearance when the spring is compressed, such that misalignment of the push rod due to manufacturing tolerances is also eliminated. This contact resists misalignment between the power spring plate and the diaphragm plate, and consequently the diaphragm. There is some small radial clearance between the outer periphery of the diaphragm plate and the power spring plate such that the two members are "free floating" and may have some small amount of relative adjustment.
Patent CA-2158791-A1 (CA)
Title: Dna sequences encoding the machado-joseph disease gene and uses thereof
Inventor: KAKIZUKA AKIRA
IPC: C12Q1/68
Filed: 1995-09-21
Abstract: A method by which a nucleotide sequence, specifically a CAG triplet repeat shown to be expanded in individuals with Machado-Joseph Disease can be identified in a sample obtainable from an individual.  The present methods can be used to identify individuals in whom the CAT triplet repeat is expanded, including methods useful to identify the protein encoded by the Machado-Joseph Disease gene.
Patent CA-2160397-A1 (CA)
Inventor: MEYER HERBERT J JR
IPC: B25B5/14
Filed: 1995-10-12
Abstract: A workpiece holding press tool with an elongated body having an annular collar extending from an end face and a plug member secured to the collar by a fastener.  The plug forms an annular groove with the body that receives a retainer clip which frictionally engages the inside surface of a workpiece to retain the workpiece on the press tool. The retainer clip is a circular spring steel wire having opposed ends with a relieved portion formed on the outside surface thereof to prevent scratching, marring  or  otherwise  damaging  the  inside  surface  of  the workpiece.  In another embodiment, a second plug is added to provide a second annular groove to receive a second retainer clip for holding elongated workpieces having a cylindrical inside diameter.
Patent CA-2164504-A1 (CA)
Title: Process for manufacturing an antiperspirant stick
Inventor: CARLSON JEFFREY R SR
IPC: A61K8/39
Filed: 1994-05-26
Abstract: The present invention provides a process for making a solid antiperspirant stick comprising a particulate aluminum antiperspirant salt suspended in an anhydrous carrier vehicle, wherein said carrier vehicle comprises a high melting component which melts at 70 °C or higher. This process includes heating the carrier vehicle in a closed mixing vessel to a temperature in excess of 70 °C, preferably in excess of 75 °C, to melt the high melting component, adding the antiperspirant salt to the carrier vehicle, and cooling the carrier vehicle to form a solid antiperspirant stick. The improvement of the present invention comprises cooling the carrier vehicle below 70 °C, preferably to about 65 °C or less, but above the solidification point prior to adding the antiperspirant salt and maintaining the carrier vehicle below 70 °C, preferably at about 65 °C or less, during and after the antiperspirant salt addition, thereby substantially preventing agglomeration of the antiperspirant salt into large particles, especially particles in excess of 60 microns.
Patent CA-2164800-A1 (CA)
Inventor: DICKS ANDREW LESLIE
IPC: H01M8/06
Filed: 1995-12-08
Abstract: A molten carbonate high temperature fuel cell contains a hydrocarbon-containing fuel reforming catalyst on a support.          The catalyst is produced by reducing a catalyst precursor which is prepared by intimately mixing a defined Feitnecht compound with a non-calcined alumino-silicate clay mineral and at the same time and/or subsequently but prior to calcination with at least one added stabilising additive for reducing silicon-species loss comprising an alkaline earth and/or rare earth  metal  compound,  and,  optionally,  an  alkali  metal compound, and thereafter calcining the intimate mixture.  The catalyst has been found to be suitable for the steam reforming of methane at the working temperature of the molten carbonate fuel cell and has been found to be substantially resistant to deactivation in the hot alkali metal carbonate environment.
Patent CA-2164910-A1 (CA)
Title: Method and apparatus for roller cleaning electrodes
Inventor: BONDEROFF KEN PHILIP
IPC: C25C7/06
Filed: 1995-12-11
Abstract: A novel roller cleaner and method for cleaning scale  from electrodes  of  electrolytic  cells.    In one aspect, this invention pertains to a roller anode cleaner, and a method of using it, which cleans manganese dioxide scale of anodes of electrolytic cells used in the produc-tion of zinc according to a zinc electrowinning process. A method of cleaning scale from the surface of an electrode of an electrolytic cell comprising contacting the scale on the surface of the electrode with a smooth surface rotat-able and yieldable member with a force which is sufficient to dislodge the scale from the electrode at the interface between the scale and the electrode and leaves the surface of the electrode intact.
Patent CA-2168305-A1 (CA)
Title: Method and apparatus for powder coating welded cans
Inventor: WILSON TIMOTHY E
IPC: B05D7/22
Filed: 1996-01-29
Abstract: Methods and apparatus are disclosed for spraying powder into the interior of welded hollow can bodies from a spray gun mounted to the welding arm of a can forming machine.  The spray gun can either apply a stripe of highly charged powder on the welded seam areas of hollow can bodies, or can simultaneously apply a coating of powder having a first thickness on the longitudinally welded seam areas and a second thickness less than the first thickness on the remainder of the interior surface.          Air is vented off from the powder flow being transported through the welding arm so that the powder to air ratio is increased.   Air is introduced at the downstream end of the welding arm to provide a suction force to help draw the powder flow through the welding arm and to increase the velocity of the powder flow for better tribo charging of the powder in the gun and to improve spray pattern stability.  A flow of cleaning air through the powder spray gun prevents powder from collecting on the front surface of an offset nozzle secured to the spray gun.  The gun assembly is affectively grounded to prevent arcing, and has an exterior shape which has been geometrically configured to improve powder coating of the can.
Patent CA-2169762-A1 (CA)
Inventor: CLAYBERGER CAROL
IPC: A61K49/00
Filed: 1995-06-16
Abstract: Peptides of the alpha subunit of Class II MHC antigens are employed for modulation of T-cell activity. The peptides can be used in therapies, particularly associated with tranplantation by themselves or in conjunction with other agents.
Patent CA-2171804-A1 (CA)
Title: Crosstalk noise reduction connector for telecommunication system
Inventor: AEKINS ROBERT A
IPC: H05K1/02
Filed: 1996-03-14
Abstract: A connector for communications systems includes four input terminals and four output terminals in ordered arrays. A circuit electrically couples respective input and output terminals and cancels crosstalk induced across adjacent connector terminals. The circuit includes four conductive paths between the respective input and output terminals. Sections of two adjacent paths are in close proximity and cross each other between the input and output terminal. At least two of the paths have sets of vias connected in series between the input and output terminals.      The sets of vias are adjacent.
Patent CA-2174612-A1 (CA)
Title: Thermoplastic elastomer composition
Inventor: ITOH YUICHI
IPC: C08K5/00
Filed: 1996-04-19
Abstract: The thermoplastic elastomer composition of the invention comprises a crystalline polyolefin resin (A), an olefin rubber (B), a hydrogenated styrene block copolymer (C), a softener (D), and optionally, a peroxide non-crosslinked type hydrocarbon rubber (E) in a specific amount of each, and has a gel content of not less than 97 %.  This composition may be mixed with a crystalline polyolefin resin.  The thermoplastic elastomer composition has excellent moldability and is able to provide a molded product having excellent elastomeric properties, high resistance to permanent compression set and good appearance.  In particular, a composition obtained by mixing this thermoplastic elastomer composition and a crystalline polyolefin resin shows excellent moldability.
Patent CA-2174637-A1 (CA)
Title: A surface treated steel sheet for battery containers, a battery container, and a battery produced thereof
Inventor: OHMURA HITOSHI
IPC: H01M50/128
Filed: 1994-10-03
Abstract: A steel sheet for use as a battery container is coated with a nickel-tin alloy layer on one side of the steel sheet to be used after drawing as the inner side of battery container. A battery using the surface treated steel sheet is manufactured by first filling the battery container with a positive electrode mix, composed of manganese dioxide, graphite and potassium hydroxide, and by filling the negative electrode active material, composed of zinc and potassium hydroxide.
Patent CA-2176127-A1 (CA)
Title: Methods for the treatment or prevention of conditions associated with amyloidogenic reptides
Inventor: LUNN WILLIAM HENRY WALKER
IPC: A61K31/445
Filed: 1994-12-14
Abstract: This invention provides methods for the treatment or prevention of physiological disorders associated  with an amy loidogenic peptide by the administration of a series of substituted naphthalenes, dihydronaphthalenes, benzofurans, benzothiophenes indoles, or the pharmaceutically acceptable  salts or solvates thereof.  This invention also provides methods for the treatment or prevention of Alzheimer's Disease or Down's Syndrome by the administration  of these same benzofurans or benzothiophenes or the pharmaceutically acceptable salts thereof.
Patent CA-2177558-A1 (CA)
Title: Cellulose ester wound dressing
Inventor: CHEN JOHN C
IPC: A61L15/28
Filed: 1996-05-28
Abstract: A wound dressing that releases, via hydrolysis and in a controlled manner, acetic acid when subjected to body temperatures and moisture, and is made from a cellulose ester substrate with a partial solvent thereon.
Patent CA-2179130-A1 (CA)
Inventor: NATARAJAN KADATHUR S
IPC: H04L12/70
Filed: 1996-06-14
Abstract: A method (100) transfers packets (60), including ATM cells, through a constellation of satellites (20) in a manner that is nearly transparent from the perspective of an end-to-end virtual connection. According to the method (100), a source earth station (50) transmits a connection request to a currently serving satellite (21). The currently serving satellite (21) forwards the connection request to a serving ground control station (40) which then determines which path the packets (60) are routed along corresponding to predetermined time intervals. The serving ground control station (40) transmits the routing information to the source earth station (50) and packets (60) are routed through the satellites (20) using the routing information Resource allocation information is transmitted to the other ground control stations (51) so that all stations (50, 51) have an up-to-date view of the total network state.
Patent CA-2179322-A1 (CA)
Inventor: NUBER RAY
IPC: H04N7/50
Filed: 1996-06-17
Abstract: A method and apparatus are provided for communicating VBI user information for digital television. A syntax is provided which allows the transport of closed captions, non-realtime video, sampled video and AMOL. Non-realtime video can be used to transport various types of data, such as a vertical interval test signal (VITS) through the system at full resolution. The provision in the syntax of a count for each type of VBI user information enables the adjustment of a digital television data stream to accommodate variable amounts and types of such information without space being reserved in advance. The provision of a priority number in the syntax enables decoders to discard VBI user information priorities which are not supported by the particular decoder.
Patent CA-2179931-A1 (CA)
Inventor: SATTLER HENNING
IPC: A61K31/573
Filed: 1994-12-22
Abstract: Lotion eau dans huile contenant de l'hydrocortisone-21-acétate-17-propionate.
Patent CA-2181885-A1 (CA)
Title: Benzalkonium fluoride injectable solution
Inventor: LAGNY PIERRE
IPC: A61K9/08
Filed: 1995-01-23
Abstract: Intravascular delivery solution comprising in the region of or less than 0.23 % by weight of at least one benzalkonium fluoride dissolved in an excipient injectable by intravascular means. The solution of the invention is useful for treating viral or infectious diseases, and especially immunodeficiency diseases.