baber/WOPTO huggingface dataset:
Patent RU-2717218-C1 (RU)
Inventor: BOGACHEV SERGEJ STANISLAVOVICH
IPC: A61K38/19
Filed: 2019-08-07
Granted: 2020-03-18
Abstract: Изобретение относится к медицине, а именно к онкологии и молекулярной биологии, и может быть использовано для торможения роста подкожного трансплантата экспериментальной глиобластомы человека U-87, перевитого иммунодефицитным мышам Nu/J. Мышам с подкожно перевитым графтом U-87 вводят протестированный на первом этапе препарат GcMAF RF ©  в дозе 1-2 мкг/мышь ежедневно, чередуя интраперитонеальные и интратуморальные инъекции, в течение 22 дней. Предшественник GcMAF RF ©  молекулы, витамин Д 3  связывающий белок – DBP, выделяют из белка плазмы крови человека и конвертируют в GcMAF RF ©  дегликозилированием с использованием двух ферментов гликозилаз - сиалидазы и β-галактозидазы. На первом этапе проводят оценку способности GcMAF RF ©  активировать адаптивное звено противоракового иммунного ответа. На втором этапе оценивают специфическую противораковую активность обработанных GcMAF RF ©  макрофагов. Затем проводят биологический тест на способность тормозить рост экспериментальной глиобластомы человека. Способ обеспечивает расширение арсенала технических средств, которые направлены на торможение развития глиобластомы, и, в частности, на повышение эффективности торможения роста подкожного трансплантата экспериментальной перевиваемой культуры клеток глиобластомы человека U-87, перевитого (развивающегося в форме злокачественной опухоли) иммунодефицитным мышам Nu/J (модельным животным, у которых глиобластома U-87 формирует раковую опухоль), за счет инъекций активирующего макрофаги фактора GcMAF RF © . 4 з.п. ф-лы, 5 ил., 2 табл.
Patent RU-2723256-C1 (RU)
Inventor: Minakov Andrej Viktorovich
IPC: C09K8/08
Filed: 2019-08-27
Granted: 2020-06-09
Abstract: FIELD: soil or rock drilling; mining.SUBSTANCE: invention relates to drilling oil and gas wells. Drilling mud contains, wt. %: propylene glycol 20.00–80.00; industrial starch 2.00; xanthane biopolymer 0.50; water is the balance.EFFECT: technical result is maintaining stability of walls of well in complex mining and geological conditions of permafrost rocks, in poorly consolidated rocks, reducing volumes of water consumption, drilling wastes, consumption of reagents.1 cl, 1 dwg, 1 tbl
Patent RU-2719201-C1 (RU)
Inventor: VAN DIJK JOPPE GIDEON
IPC: A61C17/22
Filed: 2018-04-26
Granted: 2020-04-17
Abstract: FIELD: hygiene. 
     SUBSTANCE: invention relates to the field of dental cleaning devices, in particular to the dental cleaning device. Teeth for the dental cleaning device comprises a support structure configured to cover a plurality of teeth of the dental arch. Support structure has inner surface facing tooth surface. Dental cleaning chamber is provided on inner surface side. Dental cleaning chamber comprises a flexible part of the wall deformed by creation of increased pressure or pressure release in the dental cleaning chamber. Bristles extend outward from the flexible part of the wall. In the method for teeth cleaning multiple teeth are covered by means of a nozzle, and at least one tooth brushing chamber is alternatively exposed to creation of increased pressure and pressure release. 
     EFFECT: invention is aimed at improving the efficiency of nozzle operation. 
     18 cl, 50 dwg
Patent RU-2726315-C1 (RU)
Title: Способ профилактики и снижения инсулинорезистентности у лабораторных животных
Inventor: KRASIKOV SERGEJ IVANOVICH
IPC: A61K33/00
Filed: 2020-01-09
Granted: 2020-07-14
Abstract: Изобретение относится к медицине, а именно к экспериментальной эндокринологии, и касается профилактики или снижения инсулинорезистентности. Для этого лабораторным животным (крысам линии Wistar) вводят тритерпеноид растительного происхождения – милиацин в комплексе с раствором нейтральных жиров триацилглицеринов, содержащих 32% по массе олеиновой и 59% по массе линолевой кислот. Милиацин вводят в дозе 2 мг/кг, нейтральные жиры – в дозе 25 мкл. Введение осуществляют 1 раз в сутки курсом 28 дней. Такой режим введения обеспечивает эффективное снижение инсулинорезистентности при отсутствии побочных эффектов, даже на фоне диеты повышенной калорийности, за счет нормализующего действия милиацина на углеводный обмен. 4 ил., 2 пр.
Patent RU-2743933-C1 (RU)
Inventor: WALUKAS JOEL JAMES
IPC: G01J9/00
Filed: 2018-07-27
Granted: 2021-03-01
Abstract: FIELD: device for the examination of the analyzed environment. 
     SUBSTANCE: invention relates to device for the examination of the analyzed environment, such as a avian eggs. Device contains an emitting unit for emitting light into the analyzed environment. The emitting unit contains a first radiation source for emitting a first light signal, and a second radiation source for emitting a second light signal. First and second light signals are transmitted through a quadrature phase shift environment. Detector unit is configured to detect the first and second light signals transmitted through the specified medium. In addition, the detector unit is configured to determine the relative or absolute amplitude of each of the first and second light signals. The processor is configured to process the detected signal and identify environment properties using at least one of the relative or absolute amplitudes of the first and second light signals. A corresponding method is also proposed. 
     EFFECT: provides environment properties identification.  
     24 cl, 1 tbl, 22 dwg
Patent RU-2729514-C1 (RU)
Inventor: Orlov Ilya Anatolevich
IPC: G01C21/00
Filed: 2020-02-18
Granted: 2020-08-07
Abstract: Способ определения навигационных параметров подвижного объекта с компенсацией случайных составляющих чувствительных элементов корректируемой инерциальной курсовертикали, может быть использован при создании инерциальных навигационных систем для определения навигационных параметров управляемых подвижных объектов. Сущность способа заключается в том, что помимо сигналов интегральной и внешней коррекции инерциальной курсовертикали в составе инерциальной навигационной системы формируется сигнал коррекции, компенсирующий погрешность в счислении ϕ и λ, от нестабильности параметров чувствительных элементов инерциальной курсовертикали. Сигнал разности линейной скорости объекта, полученный в инерциальной навигационной системе, и линейной скорости, полученной путем комплексирования внешних для инерциальной навигационной системы навигационных систем, подается в блок бортового вычислителя, материализующий модель погрешностей инерциальной курсовертикали вместе с сигналами, характеризующими нестабильность параметров чувствительных элементов. Техническим результатом изобретения является повышение надежности системы коррекции, уменьшение погрешности в счислении географических координат подвижного объекта за счет компенсации параметров нестабильности чувствительных элементов инерциальной курсовертикали. 1 ил., 1 табл.
Patent RU-2738132-C1 (RU)
Title: Приемный датчик для магнитно-резонансной томографии кисти руки
Inventor: Bayazitov Alfis Albertovich
IPC: A61B5/055
Filed: 2020-03-12
Granted: 2020-12-08
Abstract: Изобретение относится к медицинской физике, а именно к приемному датчику магнитно-резонансного томографа (МРТ) для приема и сбора сигнала ядерного магнитного резонанса, и может быть использовано для получения магнитно-резонансного изображения кисти руки пациента в специализированном малогабаритном травматологическом томографе. Приемный радиочастотный датчик для магнитно-резонансной томографии кисти руки включает приемную радиочастотную катушку, содержащую обмотку из электрически соединенных параллельно один другому витков, имеющих электрическое соединение проводников с оборудованием МРТ и размещенных на пустотелом каркасе овального поперечного сечения, размеры полуосей которого находятся в соотношении 2:1,5. Причем витки ориентированы ортогонально относительно продольной оси каркаса, расположены неравномерно, и расстояние между витками оптимизировано расчетным путем. Радиочастотная катушка датчика содержит обмотку из восьми витков, и расстояния между парами витков, симметричными относительно плоскости симметрии датчика, параллельной виткам, считая от центральных к крайним, находятся в соотношении: 1:2,75:5:5. Применение данного изобретения позволяет получить магнитно-резонансные изображения с высоким разрешением для конкретных областей, представляющих интерес, без необходимости перемещения радиочастотного датчика. 5 ил.
Patent RU-2757366-C1 (RU)
Title: Method for obtaining the preparation "extracore"
Inventor: OSTRONKOV VLADIMIR SERGEEVICH
IPC: A61K36/15
Filed: 2020-04-20
Granted: 2021-10-14
Abstract: FIELD: agriculture. 
     SUBSTANCE: invention relates to agriculture and pertains to a method for obtaining a preparation for plant growth regulation. A method for obtaining a preparation for plant growth regulation, including extraction of dried and ground raw materials from larch with an aqueous solution of ethyl alcohol while heating, separation and cooling of the aqueous part of the extract, supply thereof to a chromatographic column with a hydrophobic polydivinylbenzene-based sorbent and separation of fractions containing active substances eluted with an alcohol solution and mixed in the total volume, then sequentially supplied to a vacuum evaporation unit and for spray drying, through a filter, wherein larch bark crushed to the size of 1 to 3 mm is extracted, extraction is executed with a 40 to 60% aqueous-ethanol solution of alcohol at a temperature of 60°C with a raw materials : extractive agent ratio of 1:7.3, the aqueous part of the extract cooled to 37°C is first supplied to the ultrafiltration unit through nano- and microfilters for thickening and separation into an aqueous-alcohol solution and a concentrated extract, and then the concentrated extract is supplied to the chromatographic column, wherein elution is executed with 5 to 10% ethyl alcohol. 
     EFFECT: described method provides a possibility to obtain a preparation effective for plant growth regulation. 
     1 cl, 1 ex
Patent RU-2739086-C1 (RU)
Title: Method of trains control and track sections condition monitoring device for implementation thereof
Inventor: POLEVOJ YURIJ IOSIFOVICH
IPC: B61L23/16
Filed: 2020-04-24
Granted: 2020-12-21
Abstract: FIELD: rail vehicles. 
     SUBSTANCE: technical solution relates to track sections condition control and train traffic control facilities. In the proposed solution, a uniaxial trailer trolley with equipment for mobile monitoring of rail threads integrity is connected to the train and free track sections behind the train tail, a generator for supplying devices, a GLONASS receiver and a radio station are installed on the bogie, and a radio station is also installed on the locomotive. Both radio stations provide communication with the nearest stations using retransmitters installed on all locomotives. Initialisation of connection and disconnection of locomotive radio stations and radio stations on trailer trolleys from station radio stations is carried out by signals from a GLONASS receiver on boundaries of stable radio communication zones, as well as during movement in unstable radio communication zone through mobile locomotive repeaters of trains going after or before train. 
     EFFECT: higher reliability of monitoring conditions of long-distance track sections. 
     2 cl, 6 dwg
Patent RU-2744076-C1 (RU)
Inventor: MOROZOV ALEKSANDR VIKTOROVICH
IPC: B23P6/00
Filed: 2020-08-07
Granted: 2021-03-02
Abstract: FIELD: technological processes.SUBSTANCE: invention relates to recovery of shaft seating surface for rolling bearing. A cylindrical hole is drilled in the shaft, the axis of which coincides with its geometrical axis, compensation of wear by movement of metal from underlying layers of the shaft by movement of the working tool in the axial hole of the shaft. Working tool is moved relative to hole with simultaneous heating by electric contact method of deformed volume of shaft to hardening temperatures and metal is lifted along entire width of mounting surface. At reverse stroke of the tool the external surface of the shaft with phase changes is cooled down and its further mechanical treatment under the landing size.EFFECT: result is high-quality fit with tension of connection of shaft - rolling bearing.1 cl, 2 dwg
Patent RU-2749284-C1 (RU)
Inventor: ZAALISHVILI VLADISLAV BORISOVICH
IPC: C05F5/00
Filed: 2020-10-05
Granted: 2021-06-08
Abstract: Изобретение относится к сельскому хозяйству. Способ предпосевной обработки семян клевера и люцерны характеризуется тем, что молибденошеелитовые отходы растворяют в кремнийсодержащей минеральной воде в соотношении 1:100, с последующим замачиванием семян в этом растворе в течение 2-3 часов. Изобретение позволяет обеспечить значительную прибавку накопления биологического азота в почве, стимулировать процесс азотфиксации бобовых трав - клевера и люцерны, восстанавливать плодородие почвы. 1 табл., 2 пр.
Patent RU-2758023-C1 (RU)
Title: Universal rod external fixation device for osteosynthesis of injuries of musculoskeletal system in injured with polytrauma
Inventor: Valiev Erkin Iuldashevich
IPC: A61B17/60
Filed: 2020-10-21
Granted: 2021-10-25
Abstract: FIELD: medical equipment. 
     SUBSTANCE: invention relates to medical equipment, namely to external fixation devices designed to fix bones of limbs and pelvis in an acute period of injury, stabilize the musculoskeletal system in polytrauma, treat combined fractures of pelvis and hip bones. A rod external fixation device for osteosynthesis of injuries of the musculoskeletal system in injured with polytrauma for the pelvis, hip and lower leg contains rods, on which bone screws are installed by means of attachment points. Two rods are connected by means of pairs of cardan joints that ensure the fixation of a mutual position of hinge links connected by an intermediate rod. The first link of the first hinge is connected to the first rod. The second link of the first hinge is connected to the intermediate rod. The first link of the second hinge is connected to the second rod. The second link of the second hinge is connected to the intermediate rod. Attachment points of bone screws contain a bracket with a longitudinal groove, a clamp and a slider. A bone screw is fixed on the bracket by means of the clamp. The clamp is installed with the possibility of rotation and movement along the groove and fixation of the achieved position. The bracket is mounted on the slider with the possibility of rotation around the longitudinal axis and fixation of the achieved position. The slider is mounted on a rod with the possibility of movement along the rod, rotation and fixation of the achieved position. The bone screw is equipped at a working end with screw thread of transitional diameter, with a diameter of 4.5 mm designed for a far cortical layer of a bone, and with a diameter of 4.7 mm designed for a near cortical layer of a bone.  
     EFFECT: use of the invention makes it possible to provide the possibility of minimally invasive stabilization of pelvic bones, and/or femur bone, and/or shin bones in an anatomically correct position, both of one segment and adjacent segments, with the possibility of postoperative correction of the position of bones and fragments, while reducing the time of application of the device. 
     4 cl, 11 dwg
Patent RU-2768066-C1 (RU)
Title: Parachute system harness
Inventor: KRUGLIKOV VIKTOR YAKOVLEVICH
IPC: B64D17/34
Filed: 2020-12-08
Granted: 2022-03-23
Abstract: FIELD: aeronautics; aviation; cosmonautics.SUBSTANCE: invention relates to parachute equipment. Suspension system for human paratrooper systems consists of adjustable front straps, D-shaped buckles, buckles of suspension system height adjustment, cargo container carbines connection buckles, free ends, control links, leg loops with safety devices, belt fittings, chest strap, chest strap carabineer, chest strap adjustment buckle with tape, knapsack, pocket for knife-sling cutter, pocket for manual opening of the main parachute with a bowden hose, rings of the link for manual opening of the main parachute, pocket of manual opening of reserve parachute with hose-bowden and ring of manual opening of reserve parachute. It additionally comprises an information sensor of the environment, the output of which is connected to the input of the signal processing unit, the output of which is connected to the input of the device for delivering information to the parachutist. Environment information sensor is attached to the halyard.EFFECT: invention is aimed at informing the parachutist about the environment during landing.1 cl, 3 dwg
Patent RU-2756191-C1 (RU)
Title: Air tuyere of a blast furnace
Inventor: Shashero Aleksandr Sergeevich
IPC: C21B7/16
Filed: 2020-12-18
Granted: 2021-09-28
Abstract: FIELD: metallurgy. 
     SUBSTANCE: invention relates to the field of metallurgy; it can be used in the manufacture of ceramic inserts and preparation for the operation of air tuyeres of blast furnaces. The air tuyere of the blast furnace contains external and internal cups welded at the edges with a snout part and a flange to form a blast channel, a branch pipe for supplying natural gas and a ceramic insert with a thickness of at least 8 mm, deepened in the snout part of the blast channel, installed with an air gap relatively to the surface of the blast channel. The insert has a variable thickness along the length, gradually decreasing in the direction of the blast, the end of the insert from the side of its input section is beveled in accordance with the angle of inclination of the tuyere relatively to the flange. A side hole is made in the insert, beveled in accordance with the angle of natural gas supply.  
     EFFECT: invention provides an increase in the durability of the ceramic insert. 
     1 cl, 1 dwg, 1 ex
Patent RU-2753803-C1 (RU)
Inventor: Gapian Ervan Filipp Mari
IPC: G01R27/00
Filed: 2021-01-28
Granted: 2021-08-23
Abstract: FIELD: microelectronics.SUBSTANCE: the substance of the invention lies in the fact that the method for creating a self-aligning magnetic sensor contains the stages at which the use of an MTJ cell with shape anisotropy is carried out, which makes it possible to exclude the stage of annealing in an external magnetic field in the technological route, which is necessary for orienting the sensitive layer.EFFECT: acceleration of the technological production process for the manufacture of MTJ magnetic sensors.2 cl, 6 dwg
Patent RU-2763515-C1 (RU)
Title: Device for measuring dielectric properties of materials at high-temperature heating
Inventor: Krylov Vitalii Petrovich
IPC: H01P1/20
Filed: 2021-04-21
Granted: 2021-12-29
Abstract: FIELD: measuring techniques. 
     SUBSTANCE: invention relates to a technique for measuring the relative permittivity and dielectric loss tangent of materials. The device contains a cylindrical ceramic resonator with a conductive coating applied to the inner surface, bounded on one side by the upper wall of the resonator with coupling holes located below the resonator end face, movable in the resonator cavity and relative to the resonator axis, and on the other side by a movable lower piston mounted on the floor rod, heater, temperature meter. 
     EFFECT: improving the accuracy of measuring the dielectric parameters of the materials under study during high-temperature heating. 
     1 cl, 2 dwg
Patent RU-2766058-C1 (RU)
Title: System of counter-comparison of time scales with distributed amplification based on stimulated raman scattering effect
Inventor: PROKHOROV DMITRIJ VLADIMIROVICH
IPC: G04C11/00
Filed: 2021-04-29
Granted: 2022-02-07
Abstract: FIELD: physics. 
     SUBSTANCE: invention relates to devices for comparing and synchronizing time scales of remote objects using a fiber-optic communication line connecting objects. Device for comparing and synchronizing time scales of remote objects consists of two components located on distant from each other objects, contains on the first object an event timer, connected thereto a generator for forming the time scale of this object, optical pulse receiver with a spectral filter at the optical pulse carrier frequency and a computer. Optical pulse generator of first object is connected to input of splitter-couplers unit, which consists of fiber-optic splitter, first output of which is connected to first fiber-optic coupler, output of which is connected to input of photodetector, and second input to output of circulator, and the second output of the splitter is connected to the first input of the second fiber-optic coupler, the second input of which is connected to the output of the pumping lasers unit, and the output of the second coupler is connected to the input of the circulator, the input/output of which is connected to a fiber-optic communication line connecting two remote objects, and the output is connected to the input of the first coupler connected to the photodetector. Second object also includes an event timer, connected thereto an intermediate generator, to which the second object time scale generator is connected, an optical pulse receiver with a spectral filter at the frequency of the optical pulse carrier and a computer connected to the intermediate generator. Second object optical pulse generator is connected to the second object splitter-coupler unit input, which consists of a fiber-optic splitter, first output of which is connected to first fiber-optic coupler, output of which is connected to input of photodetector, and second input to output of circulator, and the second output of the splitter is connected to the first input of the second fiber-optic coupler, the second input of which is connected to the output of the pumping lasers unit, and the output of the second coupler is connected to the input of the circulator, the input/output of which is connected to a fiber-optic communication line connecting two remote objects, and the output is connected to the input of the first coupler connected to the photodetector. 
     EFFECT: high accuracy of the system, high permissible distance between objects, high accuracy of comparison or synchronization, high reliability and efficiency, as well as possibility of comparing or synchronizing time scales using only one optical fiber of arbitrary length, including “dark” fiber leased from public network operators. 
     1 cl, 1 dwg
Patent RU-2764528-C1 (RU)
Title: Method for the development of thin ore veins
Inventor: CHeban Anton YUrevich
IPC: E21D1/04
Filed: 2021-06-03
Granted: 2022-01-18
Abstract: FIELD: mining industry. 
     SUBSTANCE: invention relates to the mining industry and can be used for the development of thin ore veins, represented by strong rocks. The method includes positioning the mining complex relative to the face, ensuring the width of capture along the strike of the thin ore vein by means of the positioning mechanism, excavating the ore mass with a bucket with a hydraulic cylinder and unloading it into a dump truck. A thin ore vein is successively loosened to a working width by directional blasting. Excavation of ore mass in automatic mode is carried out with a bucket with adjustable, by means of curved movable walls, width - taking into account the power of a thin ore vein. The horizontal layer is worked out in portions with a step-by-step movement of the mining complex relative to the bottom, ensuring the working width by means of the positioning mechanism. Subsequent mining of the underlying horizontal layer is carried out by moving the mining complex relative to the bottomhole, ensuring the working width in the opposite direction. Cleaning the side from ore fines in the process of dipping the ladle into the mine is carried out by a rotary water nozzle controlled by a hydraulic cylinder. 
     EFFECT: increasing productivity and technological efficiency by increasing functionality, reliability and ensuring the selectivity of the extraction of thin ore veins, reducing dilution, and reducing the environmental burden on the environment in the mining area. 
     1 cl, 5 dwg