baber/WOPTO huggingface dataset:
Patent AT-E141288-T1 (AT)
Inventor: VAUGHAN JOAN
IPC: C12N15/09
Filed: 1990-03-20
Granted: 1996-08-15
Abstract: Mammalian melanin-concentrating hormone (MCH) is isolated from rat tissue, purified and characterized. These MCH peptides are useful for treating skin disorders, for suppressing the proliferation of skin tumor cells, such as melanomas in mammals, and for modulating the secretion of ACTH. Generally, peptides are provided which have the following formula:    <IMAGE>   or which are naturally occurring homologs of the peptide with said formula. The peptides which are the naturally occurring MCH homologs of mammalian species other than rat can also be obtained using the materials disclosed, as demonstrated specifically with human MCH, which is found to have the same structure as rat MCH. Also disclosed are the amino acid sequences of, and the nucleotide sequences of the cDNAs which encode, the putative precursors of rat MCH and human MCH. These precursors may also include one or more biologically active peptides N-terminally of the mature MCH's. Among these peptides, which are thought to be formed from the MCH precursors, are the peptide with the sequence H-Glu-Ile-Gly-Asp-Glu-Glu-Asn-Ser-Ala-Lys-Phe-Pro-Ile-NH2, which is cross-reactive with antibodies against alpha-MSH and CRF, and the peptide with the sequence H-Gly-XNGE-Phe-Pro-Ala-Glu-Asn-Gly-Val-Gln-Asn-Thr-Glu-Ser-Thr-Gln-Glu-OH, wherein XNGE is Pro-Ala-Val or Ser-Val-Ala, which is cross-reactive with antibodies against GRF.
Patent AT-E91125-T1 (AT)
Inventor: ARMAND MICHEL
IPC: C07C315/04
Filed: 1990-04-05
Granted: 1993-07-15
Abstract: PCT No. PCT/FR90/00241 Sec. 371 Date Dec. 3, 1990 Sec. 102(e) Date Dec. 3, 1990 PCT Filed Apr. 5, 1990 PCT Pub. No. WO90/12000 PCT Pub. Date Oct. 18, 1990.The invention relates to a process for the synthesis of sulfonylmethanes and derivatives thereof of the formula M[(RSO2)2CH]m (I), in which M represents H, an alkali metal or alkaline earth metal or NR'4, R' and R are monovalent organic radicals and m represents the valence of M. The process comprises reacting an ionic carbide with a sulfonyl halide, hydrolyzing the product obtained, adding a compound MyYm, in which Y represents an anion capable of reacting with the cation of the ionic carbide to the reaction medium before or after hydrolysis to give a compound which can be separated from compound (I), and y represents the valence of Y.
Patent AT-E164517-T1 (AT)
Inventor: TAKAYAMA KUNI K
IPC: C12P19/28
Filed: 1990-07-23
Granted: 1998-04-15
Abstract: A method is disclosed for stimulating the immune systems of animals with non-toxic lipid A derivatives. The derivatives include the lipopolysaccharide (LPS) and diphosphoryl lipid A (DPLA) for Rhodopsuedomonas.
Patent AT-E110613-T1 (AT)
Inventor: CREMASCOLI LOREDANA
IPC: B24B3/54
Filed: 1990-07-20
Granted: 1994-09-15
Abstract: PCT No. PCT/EP90/01193 Sec. 371 Date Apr. 29, 1992 Sec. 102(e) Date Apr. 29, 1992 PCT Filed Jul. 20, 1990 PCT Pub. No. WO91/04132 PCT Pub. Date Apr. 4, 1991.This knife sharpening machine comprises a supporting framework (2), means (3) of holding a knife (C) on the framework (2) at a sharpening section (4), a pair of disk grinders (10) acting on the knife at the sharpening section (4) from opposed sides thereof, and motive means (22) for rotatively driving the two grinders (10) in opposite directions. Said grinders (10) are carried movably on the framework (2) each along an arcuate path (P), convexedly to the knife (C) position.
Patent AT-E104432-T1 (AT)
Inventor: IFF RENE
IPC: G01N1/24
Filed: 1991-01-09
Granted: 1994-04-15
Abstract: The collection unit (B) can be detached from the valve unit (A) and can be attached preferably by means of a rapid closure means, in particular a bayonet closure (27, 39), a thread or a plug-in closure. The valve unit (A) is spring-loaded (5) in the closure direction and opens inwards. The collection unit (B) is spring-loaded (56a) in the closure direction and opens outwards. Valve unit (A) and collection unit (B) seal one another, preferably by means of mutually matching universal ball joints (13, 59). On the valve unit (A), an exit bore may lead outwards from the exit opening, the valve rod (11) being outside the exit bore. On the closure means, the closure rod (43) may extend outwards from the opening of the collection unit. 
<??>The sole actuating device (62') acts on the closure means of the collection unit (B), preferably by means of a two-part drive device having a cam (67') coupled to the closure housing (41) and a recess (68) provided on the closure rod (43). 
<??>A sealing device (71') preferably allows the closure means to be opened only if the collection unit (B) is arranged on the valve unit (A) and is locked relative thereto in a predetermined actuating position. 
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Patent AT-E115531-T1 (AT)
Inventor: SOLOFO JONIS
IPC: C07B61/00
Filed: 1991-03-05
Granted: 1994-12-15
Abstract: Process for preparing an alkylated aromatic product (12) by alkylation of an aromatic compound (1), the alkylation giving a number of alkylated aromatic products, this process being characterised by the following points: 
 
  a) the aromatic compound (1) is reacted with an alkylating agent (2) in the presence of an alkylation zeolite (4); 
  b) the alkylated aromatic product (12) is separated from the alkylation products by crystallisation; 
  c) the uncrystallised part (13) of the alkylated aromatic products is subjected to a dealkylation in the presence of a dealkylation zeolite (15); 
  d) the regenerated aromatic compound (1b) is recycled to make it react again with the alkylating agent (2) in the presence of the alkylation zeolite (4). Alkylated aromatic compounds (12) obtained by this process, especially 2,6-dicyclohexylnaphthalene. 
 
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Patent AT-E108676-T1 (AT)
Inventor: CHIESI PAOLO
IPC: A61M15/00
Filed: 1991-04-08
Granted: 1994-08-15
Abstract: This invention relates to a new inhaler for the local administration of powdered drugs to the respiratory tract. The apparatus consists of a nozzle (1) and a main body (2) which itself defines a storage chamber (8) for the medicinal substance, a dosing means (14,17) which supplies precisely measured doses of the drug and a dispensing system (18,19) which pours the dose of the drug delivered into a collecting chamber (24). The cavity (4) of the nozzle (1) communicates with the collecting chamber (24) through a central channel (6) designed to reduce air flow resistance as much as possible. Lateral holes (23) provided in the body (2) of the inhaler allow for the passage of air from the outside. Upon inhalation, a negative pressure is created in the chamber (24) in which the dose of powder delivered is collected, drawing an air inflow from the outside. The air flow is mixed with the medicinal substance particles and through the central channel (6), enters the cavity (4) of the nozzle (1) from where it is directly inhaled. <IMAGE>
Patent AT-E121891-T1 (AT)
Inventor: DE VRIES REIN JAN FOLKERT
IPC: H04Q11/04
Filed: 1991-03-27
Granted: 1995-05-15
Abstract: The invention relates to a method for switching packets, which are transferrable by transmission cells and comprise a control code, in a switching system having a number of inputs and a number of outputs, from the input at which the packet appears to a specific output derived from the control code of the packet. The invention provides that the packets appearing at the inputs are fed, via a number of first transmission channels containing first transmission cells, to a number of second transmission channels, containing second transmission cells, leading to the outputs of the switching system, a packet of this type transferred by a first transmission cell always being transmitted to the next sequential transmission cell, which is not already occupied by another packet, of that second transmission channel which leads to the specific output derived from the control code. <IMAGE>
Patent AT-E89479-T1 (AT)
Inventor: RHEINBERGER VOLKER DR
IPC: A61K6/083
Filed: 1991-03-22
Granted: 1993-06-15
Abstract: A polymerisable dental composition which is suitable as material for pulp protection and is based on at least one polymerisable monomer or prepolymer, a hardening catalyst and inorganic fillers contains as filler a glass powder containing 40-75% by weight CaO, 5-30% by weight B2O3 and 5-35% by weight SiO2.
Patent AT-E109682-T1 (AT)
Inventor: MACKRODT WILLIAM CARLYSLE
IPC: B01J23/10
Filed: 1991-07-31
Granted: 1994-08-15
Abstract: Compositions suitable for use as oxidation catalysts essentially free from elements, or compounds thereof, of Group VIII of the Periodic Table, comprise an intimate mixture of oxides of at least three elements selected from Groups IIIa and IVa of the Periodic Table, including, of the total number of Group IIIa and IVa element atoms present, a) a total of at least 60% of atoms of at least one element X selected from cerium, zirconium, and hafnium, b) a total of at least 5% of atoms of at least one other element Y different from element X and selected from the variable valency elements titanium, cerium, praseodymium, and terbium; and c) a total of at least 5% of atoms of at least one element Z differing from X and Y and selected from Group IIIa elements. Such compositions, and similar two component compositions wherein X and Y are both cerium, have, after heating for 8 hours at 1200 DEG C, a BET surface area of at least 1 m<2>.g<-><1> and are particularly useful for the oxidation of a feedstock with an oxygen-containing gas, eg catalytic combustion, especially under conditions such that the catalyst attains a temperature of at least 1000 DEG C.
Patent AT-E116936-T1 (AT)
Inventor: ISMAIL MUHAMMAD ALI
IPC: B30B9/30
Filed: 1991-02-19
Granted: 1995-01-15
Abstract: The present invention relates to a domestic waste processor (1). The processor (1) comprises a housing (2) having a plurality of inlet apertures (6) connected by delivery chutes (8) to a compactor (10) for compacting waste material (24) passing down the chute (8). The processor (1) is provided with removable containers (4) for collection of processed waste material (34). In use of the processor (1) a plurality of different types of waste (24) may be introduced into respective inlet apertures (6), compacted, and then collected in respective containers (4) which may be periodically emptied or disposed of.
Patent AT-E125183-T1 (AT)
Inventor: JONSSON HOLGER
IPC: B24B21/00
Filed: 1991-08-14
Granted: 1995-08-15
Abstract: PCT No. PCT/SE91/00537 Sec. 371 Date Feb. 9, 1993 Sec. 102(e) Date Feb. 9, 1993 PCT Filed Aug. 14, 1991 PCT Pub. No. WO92/03258 PCT Pub. Date Mar. 5, 1992.An apparatus arranged for grinding, polishing, etc. with a closed loop 5 of grinding, polishing, etc. belt mounted on the output shaft of a motor 1 and driven by a rotating drive wheel 4. This loop belt 5 is intended to be applied against a workpiece which is to be machined by means of the loop belt 5, said closed loop 5 having loop portions differing from one another in a running direction. The loop 5 is steered by steering members 2:8, 9:10, 11 to adopt an essential L-shape and comprising at least two loop portions, of which the loop portion 5d which is arranged to make contact with said workpiece is preferably selected shorter than the other loop portion 5a, 5b, 5f, 5g. Said drive wheel 4 for driving of the belt 5 is arranged displaceable relative to a foundation 17 by a guide 19 steered by the foundation 17 and turnable by means of guide members 3 arranged on the guide. An angle  phi  existing between the L-shaped coil portions 5a, 5b, 5g, 5f and 5c, 5d, 5e respectively of the loop 5 is resettable, for instance by means of resetting members 16 and is lockable by means of locking members 14, 15.
Patent AT-E165852-T1 (AT)
Inventor: MORTON TREVOR CHARLES
IPC: C07D303/22
Filed: 1991-10-03
Granted: 1998-05-15
Abstract: PCT No. PCT/AU91/00455 Sec. 371 Date May 3, 1993 Sec. 102(e) Date May 3, 1993 PCT Filed Oct. 3, 1991 PCT Pub. No. WO92/06128 PCT Pub. Date Apr. 16, 1992.Macrocyclic epoxy resins comprising at least one compound of the formula (I)     <IMAGE>  (I)  wherein n is an integer from 3 to 10. R1 and R3 are either the same or different and are selected from hydrogen, hydroxyl, alkoxy, allyloxy and epoxypropyloxy (glycidyloxy); R2 is selected from hydrogen, arylakalkyl optionally substituted with halogen, alkyl optionally substituted with halogen, and aryl optionally substituted with halogen; R4 is selected from hydrogen, alkyl optionally substituted with halogen, arylalkyl optionally substituted with alkyl or halogen, and aryl optionally substituted with halogen; R5 is selected from hydrogen, aryl and alkyl; with the proviso that the resin contains on average at least one epoxy group per molecule.
Patent AT-E125730-T1 (AT)
Inventor: ROSA WALTER DIPL-ING
IPC: B01F5/06
Filed: 1992-01-29
Granted: 1995-08-15
Abstract: A device is provided in which a preparation tank 4 is connected to the inlet of a preparation pump 5 and, for a cement suspension circulation, is for its part connected by means of a circulation line 9 to the outlet of the preparation pump 5, and in which an injecting tank 24 is connected to the inlet of an injecting pump 27 and, for a cement suspension circulation, is for its part connected by means of a circulation line 33 to the outlet of the injecting pump 24. It is in this case desired for this device to be suitable in an improved way for a cement suspension of fine cement. This is achieved by a screen 12 being fitted in the circulation line 9 of the preparation pump 5 and by the preparation tank 4 and the injecting tank 24 in each case being surrounded by a cooling device 14 through which coolant flows and which is connected to a refrigerating unit 16 through which the coolant flows. The screen in the circulation line has the effect of preventing any formation of lumps and, since the cooling devices are provided, the preparation pump and the injecting pump can operate at higher speeds. <IMAGE>
Patent AT-E155181-T1 (AT)
Inventor: OBERWEILER GUENTER DR-ING
IPC: E01B1/00
Filed: 1992-04-14
Granted: 1997-07-15
Abstract: A ballastless superstructure for railways is produced, with a support plate, which is arranged on a substructure designed according to the local requirements, and, supported thereon, a track grid, the surface (3) of the support plate (2) being adapted, accurate to at least +/- 2 mm, to the required dimension and the support plate (2) having in its central region, i.e. over a given width to the right and left from its centre line (7) and at least in the region of the sleepers (5) a lateral force base (6) which projects by a given amount above the surface (3) of the support plate (2) and is positively connected to the sleepers (5) of the track grid (4). <IMAGE>
Patent AT-E112987-T1 (AT)
Inventor: REHAG KLAUS
IPC: B21B13/00
Filed: 1992-07-13
Granted: 1994-11-15
Abstract: A cold pilger rolling mill includes a reciprocating roll stand and a crank drive connected to the roll stand through connecting rods. The crank drive includes three shafts arranged parallel to each other and spaced apart at equal distances. The middle shaft is a crank shaft connected through crank pins with the connecting rod. A main weight for balancing half of the inertia forces of the roll stand is arranged eccentrically relative to the axis of rotation on the crank of the crank pin offset by 180 DEG  from the pivot point of the connecting rod. On the two other shafts are arranged two additional weights of equal size which balance the other half of the inertia forces of the roll stand. For a synchronous rotation of the shafts and their weights, the shafts are connected by spur gears meshing with each other in such a manner that the additional weights rotate in opposite directions to the main weight with the same rate of rotation and, at the dead centers of the roll stand, the sum of the main weight and the additional weights acting on the roll stand corresponds to the inertia forces of the roll stand and of any other weights moved with the roll stand.
Patent AT-E115476-T1 (AT)
Inventor: CHAREIRE JEAN-LOUIS
IPC: B61H5/00
Filed: 1992-04-08
Granted: 1994-12-15
Abstract: The invention relates to a braking device using multiple discs for a vehicle, especially a railway vehicle, equipped with a braking decelerator. The device advantageously comprises:   - a first set of discs (4) produced in a metal material and some of which are integral in rotation with a rotating element (2) of the said vehicle; - first pressure means (6) capable of acting on the first set of discs (4), and linked to a fixed element (3) of the said vehicle; - a second set of discs (5) produced in carbon, some of which are integral in rotation with the said rotating element; - second pressure means (7) capable of acting on the second set of discs and linked to the said fixed element; - means (CA, LA, DI) for controlling the actuation of the said first pressure means (6) as soon as the vehicle, braked by the decelerator, reaches a limit speed; and, - means (DE) for detecting an operating anomaly of the said decelerator and bringing the second pressure means (7) into play.   <IMAGE>
Patent AT-E140864-T1 (AT)
Inventor: GSCHWEND NORBERT PROF DR MED
IPC: A61F2/00
Filed: 1992-06-04
Granted: 1996-08-15
Abstract: The invention shows a patella prosthesis, which consists of an artificial slide member (2) made from polyethylene with sliding surface (3), with the slide member (2) being mounted on the rear of the patella (1) by means of an attachment. The sliding surface (3) consists of the sector of a polyethylene sphere, which comprises a metal grid (4) of an attachment member (9). The attachment member consists of a metal sandwich construction having a central support sheet and metal grids (4, 6) spot welded on both sides, with bevelled sheet metal flanges (7) for the primary attachment of the support sheet (5) protruding through recesses (8) in the metal grid (6) on the side of the patella.
Patent AT-E139135-T1 (AT)
Inventor: MALTSEV ALEXANDR ANATOLIEVICH
IPC: A63C11/24
Filed: 1992-02-03
Granted: 1996-06-15
Abstract: A ski-stick for skating step comprises a rod (1) with a supporting element (2) on one of its ends and with a handle (3) mounted on the other end and consisting of an interconnected tube (4) and a cross-piece (5) with sections (6, 7) of different lengths. The larger section (6) is inclined at an acute angle to the axis (8) of the tube (4) and in the horizontal plane is oriented at an obtuse angle ( beta ) in relation to the smaller section (7) and is swung towards the side opposite to the side on which is located the means (10) for fastening the strap. The stick comprises a boss (9) extending beyond the cross-piece (5) and offset in relation to the axis (8) of the tube (4) in the direction of the smaller section (7) of the cross-piece (5). The horizontal axis (11) of the cross-section of the boss (9) located in the plane perpendicular to the axis (8) of the tube (4) is offset in relation to the horizontal axis (8) of the tube (4). <IMAGE>   <IMAGE>
Patent AT-E158802-T1 (AT)
Inventor: CRAUN GARY PIERCE
IPC: C08F283/10
Filed: 1993-05-21
Granted: 1997-10-15
Abstract: Coating compositions containing aqueous dispersion of higher molecular weight epoxy resin are produced by advancing the molecular weight of an aqueous dispersion of a low molecular weight epoxy resin having a number average molecular weight between about 360 and 2 000. The water dispersed low molecular weight epoxy resins are advanced in molecular weight by coreaction with a diphenol at temperatures above about 105 DEG C and at pressures above about 34 475 N/m<2> over atmospheric (5 psig) to produce the aqueous dispersed high molecular weight epoxy resin. The aqueous dispersed high molecular weight epoxy resin can be further copolymerized with ethylenic monomers, if desired, to produce an acrylic epoxy emulsion binder useful in protective coatings.
Patent AT-E117207-T1 (AT)
Inventor: MORITA YUTAKA
IPC: A61K9/06
Filed: 1993-07-15
Granted: 1995-02-15
Abstract: To provide a stable peparation which does not produce cystalline hydrates, by making a preparation containing azelastine hydrochloride and a fatty acid of 8 or more carbon atoms, as well as an azelastine hydrochloride preparation of the same composition as the above which has excelent percutaneous and mucosal absorbability. A fatty acid of 8 or more carbon atoms is added to azelastine hydrochloride and adjusted to a pH of 6 to 9. For an increase in the percutaneous absorbability, 1, 2 or more ingredients selected from the group consisting of ethanol, isopropanol and polyhydric alcohols are included therein, and for preparations an apropriate amount of lecithin is included optionally.
Patent AT-E194003-T1 (AT)
Inventor: BOGESO KLAUS
IPC: C07D241/04
Filed: 1993-04-23
Granted: 2000-07-15
Abstract: Trans isomers of 1-piperazino-1,2-dihydroindene compounds having formula (I),    <IMAGE>  I  wherein X and Y are hydrogen, halogen, trifluoromethyl, alkyl, alkylthio, trifluoromethylthio, alkoxy, hydroxy, alkylsulfonyl, amino, alkylamino, nitro or cyano; Ar is a phenyl, thienyl or furyl group, each optionally substituted; R1 is hydrogen, or optionally hydroxy substituted alkyl, alkenyl, cycloalkyl or cycloalkylalkyl; R2 is alkyl, alkenyl, cycloalkyl, or cycloalkylalkyl; or R1 and R2 together form a 5 to 7-membered heterocyclic ring fused with the piperazine ring, which ring may be substituted with hydroxy; R3 is hydrogen, alkyl, alkenyl, cycloalkyl or cycloalkylalkyl; or R2 and R3 together form a 3 to 7-membered carbocyclic ring which is spiro-fused to the piperazine ring; and R4 is hydrogen or alkyl. The compounds of the invention have potent antagonist action on dopamine D1 receptors and are useful in the treatment of diseases of the central nervous system, such as psychoses, schizophrenia (positive as well as negative symptoms), anxiety, depression, sleep disturbances, migraine, Parkinson's disease or cocaine abuse.
Patent AT-E141025-T1 (AT)
Inventor: FERRARIO BRUNO
IPC: F04B27/02
Filed: 1993-04-23
Granted: 1996-08-15
Abstract: An improved high-capacity getter pump, suitable for creating and maintaining the vacuum, comprising a plurality of porous sintered blades made from a non-evaporable getter material and having a first main surface; a second main surface, parallel to said first surface and spaced therefrom by a thickness of 0.5-5.0 mm; wherein said blades are arranged in a housing and are separated from each other by a gas conductance, with the adjacent surfaces of adjacent blades being spaced from each other by a distance of 0.5-10 mm.
Patent AT-E194658-T1 (AT)
Inventor: HARLAND RICHARD M
IPC: A61K38/00
Filed: 1993-09-02
Granted: 2000-07-15
Abstract: A novel and soluble polypeptide that is highly conserved among vertebrates has been discovered, which is designated "noggin." The properties of noggin include dorsal growth inducing activity. Noggin and activin act synergistically to produce dorsal mesoderm. Noggin's cDNA has been cloned. Several expression systems have been successfully used to express biologically active noggin. Amino acid sequences representing completely conserved portions as between frog noggin and mouse noggin are: QMWLWSQTFCPVLY (SEQ ID NO:3); RFWPRYVKVGSC (SEQ ID NO:4); SKRSCSVPEGMVCK (SEQ ID NO:5); LRWRCQRR (SEQ ID NO:6); and, ISECKCSC (SEQ ID NO:7).
Patent AT-E141858-T1 (AT)
Inventor: MANSSON PER
IPC: G02C7/04
Filed: 1993-10-06
Granted: 1996-09-15
Abstract: In a method for producing intraocular lenses with improved optical properties, applying to the optical part of the lens a coating to protect the surface during one or more processing steps which are carried out under conditions so that the protective coating is essentially insoluble and remains adhered to the lens, and removing the coating by changing the conditions which make the coating adhere to the lens.