baber/WOPTO huggingface dataset:
Patent NZ-553500-A (NZ)
Title: Cysteine engineered antibodies and conjugates withCysteine engineered antibodies and conjugates with a free cysteine amino acid in the heavy chain a free cysteine amino acid in the heavy chain
Inventor: EIGENBROT CHARLES W EIGENBROT
IPC: C12N5/071
Filed: 2005-09-22
Abstract: Disclosed is a cysteine engineered antibody compriDisclosed is a cysteine engineered antibody comprising a free cysteine amino acid having a thiol reasing a free cysteine amino acid having a thiol reactivity value in the range of 0.6 to 1.0; and a sectivity value in the range of 0.6 to 1.0; and a sequence in the heavy chain selected from SEQ ID NOSquence in the heavy chain selected from SEQ ID NOS: 11, 12, 13, and 15: LVTVCSASTKGPS  SEQ ID NO:11 : 11, 12, 13, and 15: LVTVCSASTKGPS  SEQ ID NO:11 LVTVSCASTKGPS  SEQ ID NO:12 LVTVSSCSTKGPS  SEQ ID LVTVSCASTKGPS  SEQ ID NO:12 LVTVSSCSTKGPS  SEQ ID NO:13 HTFPCVLQSSGLYS   SEQIDNO:15 where the cysteiNO:13 HTFPCVLQSSGLYS   SEQIDNO:15 where the cysteine in SEQ ID NOS: 11, 12, 13, and 15 is the free cne in SEQ ID NOS: 11, 12, 13, and 15 is the free cysteine amino acid. Also disclosed are antibody-drysteine amino acid. Also disclosed are antibody-drug conjugate compounds with the cysteine engineereug conjugate compounds with the cysteine engineered antibody described above and a drug moiety selecd antibody described above and a drug moiety selected from a maytansinoid, an auristatin, a dolastatted from a maytansinoid, an auristatin, a dolastatin, and a calicheamicin.                          in, and a calicheamicin.
Patent NZ-554022-A (NZ)
Title: Polypeptide binding agents of human angiopoietin-2
Inventor: OLINER JONATHAN DANIEL
IPC: A61K38/08
Filed: 2002-10-11
Abstract: Disclosed is a polypeptide capable of binding Ang-2 comprising an amino acid sequence of the formula RPe3e4e5e6e7G (SEQ ID NO: 73) wherein e5 is a neutral polar or an acidic amino acid residue; e4 is an acidic amino acid residue; e5 is a neutral polar or an acidic amino acid residue; e6 is a neutral hydrophobic amino acid residue; e7 is a neutral hydrophobic amino acid residue; wherein further, at least two of e3 is Y or C, e4 is E, or e6 is M; or a physiologically acceptable salt thereof. Also disclosed are polypeptides of the formula f1f2f3f4RPf7f8f9f10f11Gf13f14f15f16f17f18f19f20 wherein f1-f4, f7-f11 and f13-f20 are as defined. The compounds of the invention are useful in the treatment of angiogenesis. (62) Divided Out of 531902
Patent NZ-571974-A (NZ)
Title: Gripper for holding and conveying flat objects
Inventor: MADER CARL CONRAD
IPC: B25B5/04
Filed: 2007-04-07
Abstract: A gripper for holding and conveying flat objects (P) in a firmly held manner, in particular printed material such as newspapers, magazines or brochures, comprises two clamping tongues (4 and 5) which can pivot relative to one another into an open and into a closed configuration, wherein the clamping tongues (4 and 5) are pressed against one another in the closed configuration. The distal ends of at least one of the clamping tongues (4 and 5) are fitted with two elastic arms (30) that extend laterally away from the clamping tongue, and are resilient in the same direction as the clamping force, a clamping jaw (10, 11) being arranged at the free end of each of the arms. The contact surfaces of the clamping jaws of at least one clamping tongue adapt to fit the contact surface of an opposite clamping jaw or a clamped object, under compression force, for example in that they are mounted on the arm (30) by means of a ball joint. The gripper is particularly suitable for holding and conveying flat objects of very different types, and flat objects with zones of different thicknesses, in a firmly held manner.
Patent NZ-572634-A (NZ)
Title: Method and device for making tobacco smoke filters
Inventor: STEWART NEAL G
IPC: B31C99/00
Filed: 2007-04-17
Abstract: A composition useful for treating the substrate of a tobacco smoke filter includes one or more than one free porphyrin or one or more than one free metal phthalocyanine or both, a solvent such as triacetin, ethanol or isopropanol, and a polycationic polymer selected from the group consisting of poly(propyleneimine), polyvinylamine, poly(2-ethylaziridine), poly(2,2-dimethylaziridine) and poly(2,2-dimethyl-3-n-propylaziridine), or polyethyleneimine (PEl).
Patent NZ-575246-A (NZ)
Title: Isothiazolin-3-one-containing antimicrobial composition
Inventor: CHOI SUNGMEE
IPC: A01N59/20
Filed: 2007-09-04
Abstract: Provided is an antimicrobial composition concentrate comprising: at least one isothiazolin-3-one selected from a group consisting of 2-n-octyl-4-isothiazolin-3-one, N-n-butyl-1,2-benzisothiazolin-3-one, and a combination thereof, in an amount of between about 0.1 wt.% and about 40 wt.% based on the weight of the antimicrobial composition concentrate; at least one alkyl amine comprising a tertiary amine having methyl or ethyl substituents together with a long chain substituent having an average chain length of between 8 and 18 carbons per molecule of the tertiary amine, in an amount of between about 2 wt.% and about 80 wt.% based on the weight of the antimicrobial composition concentrate; at least one surfactant present in an amount of between about 1 wt.% and about 50 wt.% based on the weight of the antimicrobial composition concentrate; and at least one solvent present in an amount of between about 1 wt.% and about 30 wt. % based on the weight of the antimicrobial composition concentrate.
Patent NZ-576322-A (NZ)
Title: Rekeyable lock assembly with locking bar
Inventor: CHONG GERALD B
IPC: E05B27/00
Filed: 2006-12-04
Abstract: A lock cylinder (10) has a reset condition wherein the lock cylinder can be put into a "learn" mode. In the "learn" mode, the original key can be removed and replaced by replacement key and, when the replacement key is removed, the lock cylinder is rekeyed to the new key. The original key no longer operates the rekeyed lock cylinder.
Patent NZ-579947-A (NZ)
Title: Actin 1 plant polynucleotide promoter sequences from Festuca arundinacea
Inventor: HALL CLARE
IPC: A01H1/00
Filed: 2005-06-14
Abstract: Discloses isolated plant polynucleotide promoter sequences from Festuca arundinacea which comprise a sequence in the Actin 1 promoter selected from the group consisting of: (a) SEQ ID NOs: 1-3. (b) complements of the sequence recited in SEQ ID NOs: 1-3. (c) reverse complements of the sequence recited in SEQ ID NOs: 1-3. (d) reverse sequences of the sequences recited in SEQ ID NOs: 1-3. Also disclosed are methods for using such constructs in modulating the transcription of DNA sequences of interest, together with transgenic plants comprising such polynucleotides. (62) Divided Out of 552271
Patent NZ-585031-A (NZ)
Title: An opposing electrode sensor with the activator and the electrochemical thrombin substrate coated on opposing surfaces of the working electrode and the counter electrode
Inventor: NEWMAN PETER MICHAEL
IPC: G01N33/82
Filed: 2008-10-25
Abstract: An opposing-electrode sensor comprising a working electrode, a counter electrode, an activator and an electrochemical thrombin substrate. The activator and the electrochemical thrombin substrate are coated on opposing surfaces of the working electrode and the counter electrode. The sensor detects cleavage of the electrochemical thrombin substrate in the presence of a sample.
Patent NZ-589032-A (NZ)
Title: Heating panel and method therefor
Inventor: COATES RICHARD DOD
IPC: H05B3/28
Filed: 2010-11-05
Abstract: A radiant heating panel, for typical use as cover for interior walls and ceilings, is provided, that is manufactured in a continuous process involving at least one sheet material, a settable material and a heating element. A method of installing such a heating panel is also provided, along with an apparatus and method required to terminate the heating panel.
Patent NZ-590355-A (NZ)
Title: Stat3 inhibitor containing quinolinecarboxamide derivative as active ingredient
Inventor: ASAI AKIRA
IPC: A61P19/02
Filed: 2009-07-10
Abstract: 590355 Disclosed are N-[1,3,4-oxadiazol-2-yl]-4-quinolinecarboxamide derivatives as represented by the general formula (I), wherein R4a represents a hydrogen atom; W represents a single bond or an unsubstituted alkylene group; X represents an oxygen atom, a sulfur atom, or NR34; and wherein the remaining substituents are as defined herein. Representative compounds include N-[5-(2-furyl)-1,3,4-oxadiazol-2-yl]-2-phenyl-4-quinolinecarboxamide, 2-phenyl-N-(5-phenyl-1,3,4-oxadiazol-2-yl)-4-quinolinecarboxamide, N-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-phenyl-4-quinolinecarboxamide, 2-phenyl-N-[5-(3-pyridyl)-1,3,4-oxadiazol-2-yl]-4-quinolinecarboxamide and N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-4-quinolinecarboxamide. Further disclosed is a pharmaceutical composition, containing as an active ingredient, a quinolinecarboxamide derivative as defined above, or a pharmacologically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent excipient and/or adjuvant for the treatment of cancer.
Patent NZ-594969-A (NZ)
Title: Screen tensioning mechanism wherein tapered internal profile receives a resilient tail portion
Inventor: LICCIARDI DI STEFANO CARMELO JOSEPH
IPC: B07B1/48
Filed: 2011-09-02
Abstract: Disclosed is a screen tensioning mechanism (100) for use in a retractable blind. The screen tensioning mechanism (100) comprises a projecting member (102) and a housing member (110). The projecting member (102) has a head portion (104) and a resiliently deformable tail portion (106). The housing member (110) comprises a first opening (114) adapted to receive an end of a support rod. The second opening (112) has a tapered internal profile that is adapted to forcibly receive the tail portion (106) by inwardly displacing the tail portion (106). In use, the resiliently deformable tail portion (106) biases the projecting member (102) axially outward from the support rod.
Patent NZ-596882-A (NZ)
Title: Disubstituted phthalazine hedgehog pathway antagonists
Inventor: WILSON TAKAKO
IPC: A61K31/502
Filed: 2010-06-15
Abstract: Abstract 596882 The present disclosure relates to novel 1,4-disubstituted phthalazine of formula (I ) hedgehog pathway antagonists useful in the treatment of cancer. Disclosed are compounds of formula (I) including: 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide, 2-Chloro-4-fluoro-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)benzamide, And 4-(Difluoromethoxy)-Nmethyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)benzamide
Patent NZ-599029-A (NZ)
Title: Drive assembly, piston rod, drug delivery device, and use of a spring
Inventor: VEASEY ROBERT
IPC: A61M5/24
Filed: 2010-09-29
Abstract: The drive assembly may comprise a housing (10A, 10B, 10C), a piston rod (20) being axially displaceable and rotatable with respect to the housing, a drive member (30) being axially displaceable, and a rotational bias member (50) being operable to transfer a resilient bias to the piston rod. The drive assembly may be configured such that, for setting a dose, the drive member is proximally axially displaceable with respect to the housing and the piston rod from a rest position to a dose set position. When setting the dose, the piston rod may be rotated in a first rotational direction and, subsequent to the rotation in the first rotational direction, rotated in a second rotational direction with respect to the housing and the drive member. Further, a piston rod and a use of a spring are provided for.
Patent NZ-600440-A (NZ)
Title: Method to shrinkproof wool by plasma polymerization
Inventor: CARR Christopher
IPC: B05D7/24
Filed: 2010-09-28
Abstract: Disclosed herein is a method of treating wool in the form of a fibre, yarn, sliver, fabric or garment to make it shrinkproof and to improve water and oil repellency, wherein the method comprises: applying a polymer coating (preferably a fluoropolymer coating) by plasma polymerisation characterised in that the fibre, yarn, sliver, fabric or garment has undergone a pre-treatment to coat the fibre surface with a polymer, the pre-treatment comprising the Chlorine / Hercosett process, and in that in a preliminary step before the plasma polymerisation, a continuous power plasma is applied to the wool in the presence of an inert gas. Coating the polymer on wool by plasma polymerisation process reduces shrinkage due to felting during laundering. The method may further include application of nanoparticles (preferably silicon nanoparticles) to the fibre, yarn, sliver, fabric or garment.
Patent NZ-605690-A (NZ)
Title: Oxadiazole inhibitors of leukotriene production
Inventor: BARTOLOZZI ALESSANDRA
IPC: C07D498/04
Filed: 2011-08-11
Abstract: Disclosed are 1,2,4-oxadiazoles of formula (I): or pharmaceutically acceptable salts thereof, for example; 5-(4-{ 2-[5-(5-methoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl} phenyl)pyrimidin-2-amine. The invention also relates to pharmaceutical compositions comprising these compounds, processes for preparing these compounds and intermediates useful in these processes. The compounds are intended for use in the treatment of leukotriene-mediated disorders including cardiovascular, inflammatory, allergic, pulmonary and fibrotic diseases, renal diseases and cancer.
Patent NZ-605737-A (NZ)
Title: Method of preparing deer bone extract having increased amount of ganglioside
Inventor: HO BONG LEE
IPC: A23L13/30
Filed: 2013-01-14
Abstract: Disclosed herein is a method of preparing a deer bone extract in which deer bones are subjected to extraction at normal pressure and extraction under pressure to minimize decomposition of deer bone-derived gangliosides by heat and to increase protein extraction yield
Patent NZ-609829-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: A23L33/00
Filed: 2009-04-28
Abstract: The disclosure relates to a method of making an animal feed comprising treating a polysaccharide containing biomass with electron beam irradiation. In an exemplary embodiment of the disclosed method, biomass comprising polysaccharides in the form of cellulose, hemicellulose, or starch, is exposed to at least 5.0 Mrad of radiation, utilizing an electron beam operating at a power of at least 5 kW, to produce a feed material comprising a material having a number average molecular weight of from about 3,000 and 50,000 Daltons, the feed material having a nutrient availability of protein or amino acid greater than the nutrient availability of protein or amino acid in the biomass. wherein nutrient availability is determined by feeding equal amounts of the feed material and the biomass to at least two distinct groups of one or more animals, and comparing fecal loss of protein or amino acid for the two groups, and providing the feed material to an animal for consumption by the animal. Further embodiment’s relate to comminuted biomass being used as the feed-stock, the biomass having been dried to 5% or less moisture, cooling the biomass after irradiation followed by a second treatment with irradiation and further treating the biomass with enzymes.
Patent NZ-611643-A (NZ)
Title: Co-current and counter current resin-in-leach in gold leaching processes
Inventor: CHOI YEONUK
IPC: C22B11/00
Filed: 2011-12-07
Abstract: 611643 Disclosed is a method, comprising: leaching, by thiosulfate, a gold and/or silver-containing material in at least one of an ion-exchange resin-in-leach and ion-exchange resin-in-pulp circuit, the circuit comprising a co-current portion where the gold and/or silver-containing material and a gold and/or silver collecting ion-exchange resin flow co-currently and a counter-current portion where the gold and/or silver-containing material and gold and/or silver-collecting ion-exchange resin flow counter-currently, wherein the gold and/or silver-containing material flows first through the co-current portion and second through the counter-current portion. Further disclosed is metal recovered by the method.
Patent NZ-617823-A (NZ)
Title: Method and apparatus for dehydrating veneer
Inventor: SHIN-ICHI SAKAMOTO
IPC: F26B15/12
Filed: 2013-11-15
Abstract: 617823 Method and apparatus for dehydration of veneer sheet having therein a knot are disclosed. Veneer dehydration apparatus includes a first stationary single dehydrating roller and a plurality of second movable sectional dehydrating rollers, which rollers are disposed one above the other so that a nip through which a veneer sheet for dehydration is moved is formed between the first and second rollers. A stop device determines the initial position of each second roller relative to the first roller where a predetermined spaced distance is formed between the first and the second rollers. A yieldable urging device urges each second roller to the initial position. The second roller is movable away from the initial position against the urging force of the urging device independently of the other second rollers by a knot present in the veneer sheet and just moving through the nip between the second roller and the first roller.
Patent NZ-626951-A (NZ)
Title: Amidine substituted beta - lactam compounds, their preparation and use as antibacterial agents
Inventor: KLENKE BURKHARD
IPC: C07D417/14
Filed: 2013-01-23
Abstract: The present disclosure relates to novel β-lactam compounds of formula (I), their preparation and use. In particular, this disclosure relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation. The compounds are useful in treating bacterial infections. Examples of compounds that fall within the scope of formula (I) are: (2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{ [2-(4-carbamimidoyl-3-hydroxyphenoxy)ethoxy]imino} -N-[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]ethanamide; (2S,3S)-3-{ [(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{ [2-(4-carbamimidoyl-3-hydroxyphenoxy)-ethoxy]imino} acetyl]amino} -2-methyl-4-oxoazetidine-1-sulfonic acid and (2S,3S)-3-{ [(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-({ 2-[(6-carbamimidoylpyridin-3-yl)oxy]ethoxy} -imino)acetyl]amino} -2-methyl-4-oxoazetidine-1-sulfonic acid
Patent NZ-718812-A (NZ)
Title: Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
Inventor: EDER MATTHIAS
IPC: C07D295/145
Filed: 2014-10-17
Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment of various disease states of prostate cancer. Thus, the present invention concerns compounds that are represented by the general Formulae (la) or (lb).
Patent NZ-725176-A (NZ)
Title: Methods and apparatus for signaling user allocations in multi-user wireless communication networks
Inventor: TIAN BIN
IPC: H04W84/12
Filed: 2015-05-06
Abstract: With limited communication resources, it is desirable to reduce the number of bits required to convey this physical layer control information, especially as multiple types of traffic are concurrently sent from an access point to multiple terminals. In one aspect, there is provided a method of wireless communication comprising: generating, at an access point, a message for transmission over at least one channel, the message comprising: a first signal field indicative of a length of a first message after the first signal field; and a second signal field indicative of at least one channel assignment, the second signal field having a variable length, wherein the second signal field comprises one or more of a number of stations served and a list of station identifiers, and wherein the at least one channel assignment comprises a bitmap indicating a channel assignment for each station identifier in the list of station identifiers; and transmitting the message to one or more wireless devices.
Patent NZ-733919-A (NZ)
Title: System and method for producing high-purity vanadium pentoxide powder
Inventor: ZHU QINGSHAN
IPC: C01G31/04
Filed: 2016-01-28
Abstract: The present invention provides a system and method for producing high-purity vanadium pentoxide powder. Industrial grade vanadium pentoxide is converted to vanadium oxytrichloride by low temperature fluidizing chlorination, wherein chlorinating gas is preheated via heat exchange between fluidizing gas and chlorination flue gas, and an appropriate amount of air is added to enable a part of carbon powder to combust so as to achieve a balanced heat supply during the chlorination, thereby increasing the efficiency of chlorination and ensuring good selectivity in low temperature chlorination. The vanadium oxytrichloride is purified by rectification, and then subjected to fluidized gas phase hydrolyzation and fluidized calcination, thereby producing a high-purity vanadium pentoxide product and a by-product of hydrochloric acid solution. The high-purity vanadium pentoxide product is kept fluidized by compressed air to remove moisture and trace amount of volatile impurities from the vanadium pentoxide powder to obtain high-purity vanadium pentoxide powder and calcination flue gas, and the calcination flue gas is subjected to dust removing by the expansion section and then enter the gas phase hydrolyzation fluidized bed body for heat supply for fluidized gas phase hydrolyzation and fluidization of vanadium oxytrichloride.
Patent NZ-735751-A (NZ)
Title: Display system and method
Inventor: SCHOWENGERDT BRIAN T
IPC: G09G5/00
Filed: 2014-03-14
Abstract: Disclosed is a method of operation in a virtual image presentation system. The method alleviates at least some of the challenges associated with adjusting the display of a virtual object to account for movement of the head of a user of the augmented reality system. The method comprises detecting, at one or more sensors of a virtual or augmented image presentation system, an indication that indicates a first resolution corresponding to a first spacing as presented to an end user between first adjacent pixels in a first set of pixels in a first portion of a frame in a sequence of frames will differ from a second resolution corresponding to a different spacing between second adjacent pixels in a second set of pixels in a second portion of the frame as presented to the end user. The method further comprises adjusting a resolution represented by the first set of pixels in the first portion based at least in part on the indication to generate the first resolution represented by an adjusted first set of pixels in the first portion at least by modifying, at one or more modulation subsystems in the virtual image presentation system, a drive signal that drives the first set of pixels into a modified drive signal. The method further comprises presenting, in the frame including the first portion and the second portion, one or more virtual objects to the end user at least by replacing the first portion that was represented with the first set of pixels with the adjusted first set of pixels to at least render the first portion in the frame with the first resolution and the second portion in the frame with the second resolution.