baber/WOPTO huggingface dataset:
Patent BR-PI0922774-B8 (BR)
Title: composto cloridrato de nelmefeno di-hidratado, sua composição farmacêutica e processos de obtenção e produção dos mesmos.
Inventor: CARLA DE FAVERI
IPC: A61P25/30
Filed: 2009-12-04
Abstract: composto, processo para obtenção de um composto, composição farmacêutica, e, processo para produzir uma composição farmacêutica a presente invenção se refere ao cloridrato de nalmefeno di-hidratado, aos processos de manufatura de cloridrato de nalmefeno di-hidratado, a uma composição farmacêutica compreendendo cloridratro de nalmefeno di-hidratado e a um método de tratamento compreendendo administrar cloridrato de nalmefeno di-hidratado.
Patent BR-PI1006861-B8 (BR)
Title: métodos para isolar bactérias
Inventor: JEAN-PAUL LEONETTI
IPC: C12N1/00
Filed: 2010-01-18
Abstract: métodos para isolar bactérias. a presente invenção se refere a composições e métodos para identificar novas bactérias e metabólitos derivados das mesmas. mais especificamente, a invenção descreve um novo método para isolar bactérias produtoras de metabólitos de interesse a partir de amostras ambientais. particularmente, a invenção rebela um método para selecionar bactérias produtoras de antibiótico raras. a invenção pode ser usada a partir de qualquer amostra e permite o isolamento de bactérias que têm, por exemplo, interesse farmacêutico ou agroquímico.
Patent EA-037285-B8 (EA)
Title: Lipids and compositions for the delivery of therapeutics
Inventor: MANOHARAN MUTHIAH
IPC: A61K47/00
Filed: 2009-11-10
Abstract: The invention relates to lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure:salts thereof or diastereomers thereof, wherein R1 and R2 are each independently for each occurrence C10-C30alkyl, C10-C30alkenyl or C10-C30alkynyl; R3 is -aminoC1-6alkyl or -(C1-6alkyl)aminoC1-6alkyl; E is O, N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), NS(O)2N(Q), SS or O=N; and Q is H or C1-24alkyl.
Patent EA-037351-B8 (EA)
Title: Method of treating cancer using an anti-pd-1 and anti-ctla-4 antibody combination
Inventor: COGSWELL JOHN P
IPC: C07K16/28
Filed: 2013-05-13
Abstract: Described is a method for immunotherapy of a cancer patient, comprising administering to the patient an antibody. More particularly, provided is a method of treating a human subject afflicted with a cancer, comprising administering to the subject 4 doses of a combination of 1 mg/kg of an anti-PD-1 antibody and 3 mg/kg of an anti-CTLA-4 antibody at a dosing frequency of every 3 weeks for 4 doses, followed by administering the anti-PD-1 antibody at a dosage of 3 mg/kg separately at a dosing frequency of once every 2 weeks.
Patent AU-2002359951-B8 (AU)
Title: Promoters of the growth and/or differentiation of hematopoietic stem cells and/or hematopoietic progenitors
Inventor: KODAMA SHIHO
IPC: A61K38/19
Filed: 2002-12-27
Granted: 2008-11-06
Abstract: This invention has as its object providing promoters of the growth and/or differentiation of hematopoietic stem cells and/or hematopoietic progenitors which are useful as therapeutics of diseases that result from insufficient growth and/or differentiation of hematopoietic stem cells and/or hematopoietic progenitors, in particular, as therapeutics of panhematopenia and/or diseases that are accompanied by hematopoietic hypofunction. The invention attains the stated object by providing promoters of the growth and/or differentiation of hematopoietic stem cells and/or hematopoietic progenitors that contain Cofilin as an active ingredient. <IMAGE>
Patent BR-112016011737-B8 (BR)
Title: Aparelho para processamento de informação e método para processamento de informação
Inventor: YOSUKE AOKI
IPC: G06F3/12
Filed: 2014-11-25
Abstract: APARELHO PARA PROCESSAMENTO DE INFORMAÇÃO, MÉTODO PARA PROCESSAMENTO DE INFORMAÇÃO E PROGRAMA Um aparelho de processamento de informação gera dados de desenho a usar dados de impressão e informação de configuração sobre a impressão. O aparelho de processamento de informação inclui uma unidade de conversão que converte a informação de configuração sobre a impressão em informação de configuração para o aparelho; uma pluralidade de unidade de geração de dados de desenho que gera os dados de desenho com base nos dados de impressão e informação de configuração para o aparelho; e um controlador de unidade de geração que analis a informação de configuração para o aparelho selecionar uma das unidades de geração de dados de desenho e controla a unidade de geração de dados de desenho selecionada em um procedimento de controle correspondente à unidade de geração de dados de desenho selecionada.
Patent BR-112017005871-B8 (BR)
Title: Estimativa de remoção de detritos
Inventor: MORTEN LIEN
IPC: E21B21/08
Filed: 2015-09-18
Abstract: ESTIMATIVA DE REMOÇÃO DE DETRITOS. Uma primeira propriedade, derivável da massa, de um fluido de perfuração é medida em um ponto a montante de um dispositivo de remoção de detritos. Uma segunda propriedade (também derivável da massa) é medida em um ponto a jusante do dispositivo de remoção de detritos. Uma diferença entre as propriedades é determinada sobre um período de tempo para obter uma estimativa da taxa de remoção de detritos. Isto permite que a propriedade do fluido de perfuração, antes e depois da remoção de detritos, seja comparada para proporcionar uma indicação da taxa de remoção de detritos, a qual é indicativa da limpeza do poço.
Patent BR-122016004546-B8 (BR)
Title: vírus adenoassociado recombinante, método de geração do referido vírus e composição compreendendo o referido vírus
Inventor: GUANGPING GAO
IPC: C12N1/19
Filed: 2002-11-12
Abstract: a presente invenção refere-se a um método para detectar e isolar seqüências em uma amostra de dna obtido a partir de tecidos ou células. a invenção ainda fornece seqüências aav identificadas por este processo, e vetores formados usando estas seqüências.
Patent EP-1577390-B9 (EP)
Inventor: ZHOU ROULI
IPC: C07K14/435
Filed: 2003-12-24
Granted: 2011-03-30
Abstract: The invention discloses a human cancer-related gene,  LAPTM4B , its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID N o : 1, SEQ ID N o : 2, SEQ ID N o : 3, SEQ ID N o : 6, or SEQ ID N o : 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID N o : 4, SEQ ID N o : 5, or SEQ ID N o : 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID N o : 1, SEQ ID N o : 2, SEQ ID N o : 3, SEQ ID N o : 6, or SEQ ID N o : 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.
Patent EP-1683522-B9 (EP)
Inventor: TIRAULT MYRIAM
IPC: A61K31/4468
Filed: 2005-12-30
Granted: 2011-03-09
Abstract: Use of a nefopam compound (I), or its salt, for the preparation of a drug to prevent or treat the acute tolerance of morphine or the hyper-analgesic effect due to morphine administration. Use of a nefopam compound of formula (I), or its salt, for the preparation of a drug to prevent or treat the acute tolerance of morphine or the hyper-analgesic effect due to morphine administration. R 5O or is absent; R 6 and R jH or 1-6C alkyl; n : 2-4; j : 1-n; R 7phenyl, optionally substituted one or more times by H, 1-6C alkyl, 1-6 alkoxy, CF 3 or halo; and R 8-R 11H, 1-6C alkyl, 1-6 alkoxy, CF 3 or halo. An independent claim is also included for a product containing (I) and/or a morphine analgesia (to induce an analgesic effect), where (I) prevents or treats the acute tolerance of morphine or hyper-analgesic effect due to morphine. [Image] ACTIVITY : Analgesic. MECHANISM OF ACTION : N-methyl-d-aspartate receptor antagonist.
Patent EP-2109690-B9 (EP)
Inventor: JACKSON DAVID B
IPC: C12Q1/68
Filed: 2008-11-28
Granted: 2012-10-24
Abstract: There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. There is disclosed that presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, the method disclosed is for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Thus, the present disclosure provides methods for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR).
Patent AU-2003260900-B9 (AU)
Title: Improved element for forming ground covering, restraining and reinforcing structures
Inventor: FERRAIOLO FRANCESCO
IPC: E02D29/02
Filed: 2003-09-18
Granted: 2008-10-09
Abstract: An improved element for forming ground covering, restraining and reinforcing structures, comprising a lower wall, an upper wall and a front wall connected in an articulated manner, at one of its end edges at least, to an edge of the lower wall or the upper wall.
Patent AU-2005269792-B9 (AU)
Title: Substituted pyrazoles, compositions containing such compounds and methods of use
Inventor: XIONG YUSHENG
IPC: C07D401/04
Filed: 2005-07-19
Granted: 2008-11-27
Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
Patent AU-2006281232-B9 (AU)
Title: Nanoparticles
Inventor: PAUL O'BRIEN
IPC: C30B7/00
Filed: 2006-08-14
Granted: 2011-12-01
Abstract: Method for producing a nanoparticle comprised of core, first shell and second shell semiconductor materials. Effecting conversion of a core precursor composition comprising separate first and second precursor species to the core material and then depositing said first and second shells. The conversion is effected in the presence of a molecular cluster compound under conditions permitting seeding and growth of the nanoparticle core. Core/multishell nanoparticles in which at least two of the core, first shell and second shell materials incorporate ions from groups 12 and 15, 14 and 16, or 11, 13 and 16 of the periodic table. Core/multishell nanoparticles in which the second shell material incorporates at least two different group 12 ions and group 16 ions. Core/multishell nanoparticles in which at least one of the core, first and second semiconductor materials incorporates group 11, 13 and 16 ions and the other semiconductor material does not incorporate group 11, 13 and 16 ions.
Patent AU-2008260070-B9 (AU)
Title: Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles
Inventor: HEWES BECKER
IPC: A61K31/4709
Filed: 2008-05-30
Granted: 2012-01-19
Abstract: The present invention provides 4-anilino-3-quinolinecarbonitirles compounds useful for treating a subject having an BcrAbl positive leukemia that is resistant to imatinib.
Patent AU-2017204012-B9 (AU)
Title: Quarter pallet
Inventor: TAKYAR SANJIV
IPC: B65D19/24
Filed: 2017-06-14
Granted: 2019-09-19
Abstract: a pallet for transporting products thereon, the pallet comprising: a top with a product supporting surface and an opposing underside, 5 fourfeet and at least four sides, wherein the four feet each extend away from the underside of the top, have a first opening facing out through the product supporting surface, and have an inner member extending from a further opening in the sole of the foot, the part of the sole surrounding 10 the further opening connecting the inner member to an outer wall of the foot, and the inner member extending away from the sole towards the product supporting surface, the feet thus allowing stacking of a plurality of such pallets with the feet of a first such pallet extending into the first openings of a second such pallet, and with the inner member of the second such pallet extending into the second openings of the first such 15 pallet. Figure 5 to accompany the abstract upon publication 10Vz 1 -t1P20 - -,14 \42 Fig. 5 209 ILog 0 C 001 0 000~t 596 69!~ OKAf~1I 4~0I7Tufl 6" 38.9 Fig. 6
Patent DE-102014114117-B9 (DE)
Title: Fließprüfmaschine und ein dazu gehörendes Messverfahren sowie ein dazugehöriges Reinigungsverfahren
Inventor: FLOCK MARCUS
IPC: G01N33/44
Filed: 2014-09-29
Granted: 2016-02-11
Abstract: Eine Fließprüfmaschine 2, die z. B. für Viskositätsprüfungen an Kunststoffen einsetzbar ist, umfasst einen Prüfkolben 4, einen Prüfkanal 38, mindestens ein Prüfgewicht 72 und eine Antriebseinheit 92. Der Prüfkolben 4 ist mittels einer Gewichtskraft 79 des Prüfgewichts 72 durch den Prüfkanal 38 bewegbar. Mittels der Antriebseinheit 92 ist zwischen einer Anfahrstellung 151 und einer Endfahrstellung das Prüfgewicht 72 durch eine aktuatorische Zusatzkraft 108, 108‘ beaufschlagbar. Die aktuatorische Zusatzkraft 108 ermöglicht eine im Vergleich zu einer Wirkung der Gewichtskraft 79 verschnellerte Bewegung des Prüfkolbens 4 in die Richtung der Gewichtskraft 79. In einer Schmelzviskositätsprüfung wird nach einem Heizschritt ein thermoplastischer Kunststoff von einem Prüfkolben 4 durch einen Prüfkanal 38 gepresst. In einem Messvorbereitungsschritt und/oder einem Reinigungsschritt wird die Prüfmasse entlang einer Gewichtskraftrichtung 79 unter Wirkung einer aktuatorischen Zusatzkraft 108, 108‘ abgesenkt. In einem Verfahren zur Reinigung wird ein Reinigungsschritt mittels einer aktuatorischen Zusatzkraft 108, 108‘ aus der Antriebseinheit 92, die zum Antrieb einer Prüfkolbenbewegung bei einer Schmelzviskositätsprüfung dient, ausgeführt.
Patent BR-0205019-C1 (BR)
Title: Desenvolvimento em controlador eletrônico de nível de reservatório de líquidos
Inventor: MOGUI TERUAKI
IPC: G01F23/24
Filed: 2002-11-14
Abstract: "DESENVOLVIMENTO EM CONTROLADOR ELETRôNICO DE NíVEL DE RESERVATóRIO DE LíQUIDOS". Tal como definido nas correspondentes reivindicações 1, 2, 3, 4 e 5 do pedido de patente de invenção do PI0205019-6, depositado em 14/11/2002, incluindo no corpo do reservatório (7) uma resistência (10) e um termostato (11), os quais são eletricamente interligados ao controlador (1) que por sua vez é provido de funções que permitem o monitoramento e controle tanto da resistência (10) quanto do termostato (11); sendo dito controlador (1) provido de uma saída para alimentação elétrica da resistência (10) e de uma entrada para recepção das informações de temperatura da água dentro do reservatório (7), as quais são obtidas através do termostato (11).
Patent DE-3203934-C1 (DE)
Title: Limit-value detector for detecting leakage currents at high-voltage insulators which are under voltage or of stray currents in surfaces of metal bodies
Inventor: AVAKIAN EDMOND DIPL-ING PETROS
IPC: G01R15/22
Filed: 1982-02-05
Granted: 1983-05-05
Abstract: To detect the conductivity of the contamination layer of a high-voltage insulator (1) under voltage or stray currents in metal bodies (17), for example in a pipeline run parallel to a high-voltage line, a measurement value pick-up is used which consists of two electrodes (3, 4 and 15, 16, respectively) attached at a predetermined distance to the surface of the high-voltage insulator (1) or of the metal body (17), respectively, which are connected to light-emitting diodes (7, 8). The light-emitting diodes (7, 8) are associated with the end (9a) of an optical waveguide (9) which is extended to a receiving device (11). The other end (9b) of the optical waveguide (9) is associated with a photodiode (12) which feeds a display or recording device (14) via an amplifier (13). At a particular level of the leakage current occurring at the insulator (1) or at the metal body (17), the light-emitting diode (7 or 8) transmits a light signal which is transmitted via the optical waveguide (9) to the receiving device (11) where it is recorded. <IMAGE>
Patent DE-3541873-C1 (DE)
Title: Furnace vessel of an electric arc furnace
Inventor: EHLE JOACHIM DIPL-ING
IPC: F27B3/19
Filed: 1985-11-27
Granted: 1987-01-02
Abstract: A furnace vessel of an electric arc furnace has a lower vessel (2) with a refractory lining (4) and an upper vessel (3) with water-cooled wall elements (6). A part of the lower vessel which is recessed relative to the upper vessel forms a tapping region, at the level of which there is a tapping hole (8) in the bottom of the vessel. In the tapping region, the inner side of the water-cooled wall element (9) is approximately in alignment with the inner top edge of the refractory lining (4), making it unnecessary to cover the recess of the lower vessel (2). To ensure that the tapping hole (8) is accessible from above, the wall element (9) in the tapping region is pivotably mounted, e.g. about a horizontal pivot (20), and has a lower part (16) and side parts (12) which, when the wall element (9) is pivoted towards the inside of the furnace, form a shield. In the lower part (16) there is a working opening (17) which, when the wall element (9) is pivoted in, lies approximately above the tapping hole (8). The wall element (9) can be pivoted with the aid of a hydraulic cylinder (15) (Fig. 3). <IMAGE>
Patent DE-3625453-C1 (DE)
Title: Wiper, in particular for the windscreen of a motor vehicle
Inventor: F SCHMID LEOPOLD
IPC: B60S1/34
Filed: 1986-07-28
Granted: 1987-07-23
Abstract: It is the intention of the invention to design a wiper, the wiping pressure of which can be varied by means of a variable-drive mechanism for the wiping pressure during the journey and during the wiping process, in such a manner that the wiping pressure is lower in the course of the swivelling angle which the wiper blade covers from top to bottom than in the course of the swivelling angle which the wiper blade covers from bottom to top. This measure is intended to eliminate the difficulties in the driving mechanism of the wiper and the obstructions to visibility which impair road safety, which currently occur when driving quickly in heavy rain and which are caused by the build-up of the layer of water which flows upwards over the windscreen and is several millimetres thick.
Patent DE-3630292-C1 (DE)
Title: Scattered light photometer
Inventor: ADOLF SUCK THOMAS
IPC: G01N21/47
Filed: 1986-09-05
Granted: 1988-02-11
Abstract: Published without abstract.
Patent DE-3636130-C1 (DE)
Title: Safe-load eye
Inventor: SMETZ REINHARD DIPL-ING
IPC: B66C1/66
Filed: 1986-10-21
Granted: 1988-01-07
Abstract: In a safe-load eye which is intended in particular for use in combination with tipping container vehicles which are provided with connecting bollards (11), a preferably rhombic eye body (6) with an opening (7) and two longitudinal legs (8 and 9) is used. A guide passage (12) for a slide (14) which can assume two positions is arranged in one of the longitudinal legs (9). In one of the positions, the slide (14) reduces the clear width of the opening (7) in such a way that the eye body (6) cannot be removed from the stop head (10) of the connecting bollard (11). In a second position, removal of the eye body (6) from the connecting bollard (11) is possible, since a recess (16) which is shifted into the area of a window (19) of the guide passage (12) supplies sufficient clearance space for the stop body (10) of the connecting bollard (11). <IMAGE>
Patent DE-3738010-C1 (DE)
Title: Electric clock
Inventor: W HALLER ECKART
IPC: G04C3/00
Filed: 1987-11-09
Granted: 1989-05-11
Abstract: In an electric clock having a clockwork which is arranged in a housing and has an electric motor with a stator winding which is connected via wiring (terminal) posts seated in the coil form (former) to conductor tracks of a printed circuit board which carries a drive circuit generating a time-indicating signal, the printed circuit board is connected to the wiring posts via an elastomeric, electrically conductive contact member. The result is a design which is particularly favourable in terms of production engineering. It is possible to dispense with a soldering operation, which is disadvantageous from many points of view.
Patent DE-4108236-C1 (DE)
Title: Prodn. of highly accurate and/or polished surfaces - involves warming plastic component to plasticise and form it in press tool
IPC: B29C48/00
Filed: 1991-03-14
Granted: 1992-08-27
Abstract: A process for producing a highly accurate surface structure and/or highly polished surfaces includes warming the plastic component to plastify it, forming it in a press tool, cooling to below the plastification temp. and allowing the plastic to solidify. The plastic is heated outside the press tool in a plastifying unit. The temp. is measured at various points. The pressed component is transferred using a transport unit. ADVANTAGE - The process is energy efficient and has a short prodn. period
Patent DE-4143171-C1 (DE)
Title: Ball race track musical instrument - has transverse grooves in track, to hold sound bodies, and produce fall height for balls
IPC: A63F7/02
Filed: 1991-12-30
Granted: 1993-06-17
Abstract: The instrument uses balls, which roll off due to gravity. The balls act mechanically on easily exchangeable sound bars, to generate sounds. The instrument is formed as an inclined track. The track has cross grooves (12), at right angles to the movement of the balls (11). The grooves generate steps in the movement track of the balls, and form holders for the sound bars (16). The bodies are each fastened to a retainer (15), fitted into the grooves. The depth of the grooves is chosen, so that the ball falls from a height, which generates a good sound. ADVANTAGE - Gives wide opportunies to esp. a child, to choose sequence of notes.
Patent DE-4212930-C1 (DE)
Title: Insulating unit of rock-wool plates for rear-ventilated facade - has transverse strips of bonded expanded-glass granulate joining plates together having U=shaped profile to allow for attachment to support elements
IPC: E04B1/76
Filed: 1992-04-18
Granted: 1993-07-01
Abstract: The mineral- and particularly rock-wool plates (2) butt against each other via their longitudinal edges (2a). They are joined together by strips (4) at right angles to the edges, and secured to them by adhesive mortar, this being done at the factory. The strips are of expanded-glass granulate bonded by inorganic foam material, their thickness (D) being greater than the width (W) of the ventilation chamber (H) behind the facade. The strips are of sheet, U-shaped profile with holes for sticking the plates on the cross bar and the arms allows for attachment to other support elements. ADVANTAGE - Easy and rapid installation.