baber/WOPTO huggingface dataset:
Patent EP-4104175-A1 (EP)
Title: Targeted-panel tumor mutational burden calculation systems and methods
Inventor: LAU DENISE
IPC: G16B20/10
Filed: 2021-02-11
Abstract: A method and system for conducting genomic sequencing includes a first microservice for receiving an order from a physician to initiate an NGS of a patient's germ line specimen and somatic specimen using a targeted-panel, a second microservice for executing an NGS of the germline specimen to identify sequences of nucleotides in the germ line specimen using the targeted-panel to generate germ line sequencing results, a third microservice for executing an NGS of the somatic specimen to identify sequences of nucleotides in the somatic specimen using the targeted-panel to generate somatic sequencing results, a fourth microservice for executing quality control (QC) testing on the germ line sequencing results to generate a germ line QC score and on the somatic sequencing results to generate a somatic QC score, a fifth microservice for generating a clinical report, and a sixth microservice for providing the clinical report to the physician, the clinical report comprising the patient's TMB status.
Patent EP-4192834-A1 (EP)
Title: Formes à l'état solide de fézolinétant et sels associés
Inventor: CERIC HELENA
IPC: A61P5/30
Filed: 2021-08-04
Abstract: La présente divulgation concerne des formes à l'état solide de fézolinétant, contenant des sels et des cocristaux de fézolinétant, selon des modes de réalisation, des polymorphes cristallins de fézolinétant, des procédés de préparation associés, ainsi que des compositions pharmaceutiques associées.
Patent EP-4112630-A1 (EP)
Inventor: ABE HIROSHI
IPC: C07H21/02
Filed: 2021-02-19
Abstract: Provided is a method for producing a capped RNA which is an RNA having the 5'-end modified with a cap, the method including: reacting an activated capping compound represented by formula (1) below, with a monophosphate RNA having the 5'-end monophosphorylated, 
where, L represents a leaving group. 
wherein the activated capping compound is preferably a compound represented by formula (2) below.
Patent EP-4205224-A1 (EP)
Inventor: LEPIORZ MATTHIAS
IPC: H01M50/54
Filed: 2021-08-11
Abstract: Pouchzelle mit einer Plus-Kontaktfahne und einer Minus-Kontaktfahne, über die die Pouchzelle elektrisch kontaktiert und so beladen und entladen werden kann, wobei die Pouchzelle flächig ausgebildet ist und eine Zelloberseite sowie eine der Zelloberseite gegenüberliegende Zellunterseite aufweist, wobei die Plus-Kontaktfahne zelloberseitig eine Leitbeschichtung und zellunterseitig eine Isolierbeschichtung aufweist und die Minus-Kontaktfahne zelloberseitig eine Isolierbeschichtung und zellunterseitig eine Leitbeschichtung aufweist, oder umgekehrt, wobei die Plus-Kontaktfahne zelloberseitig eine Isolierbeschichtung und zellunterseitig eine Leitbeschichtung aufweist und die Minus-Kontaktfahne zelloberseitig eine Leitbeschichtung und zellunterseitig eine Isolierbeschichtung aufweist.
Patent EP-4097538-A1 (EP)
Inventor: Loo Kent Chill
IPC: A61F9/02
Filed: 2021-03-04
Abstract: A slip-resistant eyewear system comprising a nose pad comprising a securing member configured to couple to a portion of an eyewear frame and a flap pivotally coupled to the securing member, wherein an angle formed between the securing member and the flap is an acute angle. Implementations of a flap-style nose pad may comprise a pocket configured to house a preexisting eyewear nose pad therein. Other implementations of the nose pad may be configured to adhere to a preexisting eyewear frame. Use of a higher durometer and material and a lower durometer material to form the nose pads allows for a custom fit to accommodate wearers of varying facial topography avoid slippage of the eyewear system.
Patent EP-4228856-A1 (EP)
Inventor: STILSON SCOTT ALEXANDER
IPC: B25B1/24
Filed: 2021-08-18
Abstract: Selon l'invention, un doigt donné à titre d'exemple comprend un corps de doigt et une pointe de doigt. La pointe de doigt est conçue pour être montée de manière amovible sur le corps de doigt. Le doigt comprend un mécanisme de verrouillage conçu pour fixer ou coupler la pointe de doigt au corps de doigt.
Patent EP-4113855-A1 (EP)
Inventor: HUANG YINGPEI
IPC: H04B7/0456
Filed: 2021-02-04
Abstract: Disclosed in embodiments of the present application are a codebook feedback method, a network device, a terminal device, and a computer storage medium, comprising: the network device sends first indication information to the terminal device, the first indication information being used for indicating at least one set of basis vector sets, and the basis vector set comprising an FDbasis set or an SD-FD-basis set. According to the embodiments of the present application, codebook feedback amount may be reduced, and codebook feedback efficiency is improved.
Patent EP-4119678-A1 (EP)
Inventor: HIRAHARA ICHIRO
IPC: G01N33/53
Filed: 2021-03-02
Abstract: Provided is a means capable of determining the development of myocarditis or the risk thereof by a simple and minimally invasive method. A method of determining the development of myocarditis or risk thereof, wherein it is determined that myocarditis is developed or there is a risk thereof when a concentration or expression amount of ADAM28 in a body fluid sample collected from a subject is reduced compared with a reference value.
Patent EP-4214219-A1 (EP)
Title: Système et procédé d'élimination de pathogènes
Inventor: PANJWANI SHYAM
IPC: C07K1/14
Filed: 2021-08-23
Abstract: Les présents modes de réalisation concernent l'élimination de pathogènes. Les présents modes de réalisation concernent des procédés mis en œuvre par ordinateur, des systèmes informatiques et des supports de stockage lisibles par ordinateur pour prédire la performance de processus d'élimination de pathogènes.
Patent EP-4211266-A1 (EP)
Title: Tools & methods useful for detection of lactose intolerance and uses thereof
Inventor: DUCREST PERCEVENT
IPC: C12Q1/6844
Filed: 2021-09-13
Abstract: The present invention relates to a method for the detection of lactose tolerance markers in a sample by lateral flow immunoassay, a lateral flow immunoassay device, primers and extraction buffer and uses thereof and related tools and assays useful in said method.
Patent EP-4121077-A1 (EP)
Title: Compositions and methods for treating solid and soft tumors and proliferative diseases
Inventor: ALKALAY RACHEL
IPC: A61K31/045
Filed: 2021-03-19
Abstract: A method of preventing or treating solid and soft tumors and proliferative diseases in a subject in need thereof is provided. The method comprising administering to the subject an effective amount of a plant species or genus thereof-derived component selected from the group consisting of a plant part, extract thereof, fraction thereof, active ingredient thereof, synthetic analog thereof, mimetic thereof or combination thereof, wherein the component is capable of treating solid and soft tumors and proliferative diseases and wherein the plant species is selected from the group consisting of  Nigella sativa, Thymus 
 capitatus, Thymus vulgaris, 
 Origanum syriacum, Thymbra spicata, Satujera thymbra ,  Sesamum indicum, Rhus coriaria, Gynostemma pentaphyllum, Boswellia sacra and Panax 
 ginseng , preventing or treating solid and soft tumors and proliferative diseases in the subject.
Patent EP-4125654-A1 (EP)
Inventor: MAY JASON M
IPC: A61B17/70
Filed: 2021-03-04
Abstract: A spinal-surgery system having a rod receiver and/or a cap for use insertion and removal from the receiver. The cap has a generally cylindrical body, a set of opposing splay-resisting flanges, and set of opposing rotation-preventing wings, the flanges extending radially from the body along a first radial line of the body, and the wings extending radially away from the body along a second radial line of the body generally orthogonal to the first radial line. Each cap flange has a proximal-facing cap splay-resisting surface, and a distal-facing cap pop-on surface. Each receiver proximal protrusion has a proximal-facing sloped receiver pop-on surface, and a distal-facing sloped receiver splay-resisting surface. The receiver pop-on surfaces are spaced such that each cap pop-on surface contacts a respective receiver pop-on surface when the cap is centered, with the cap wings aligned between receiver arms, and moved distally to contact the receiver.
Patent EP-4119914-A1 (EP)
Inventor: PAN CHAO
IPC: G01K11/32
Filed: 2021-03-30
Abstract: Embodiments of this application provide a signal detection method and an optical time-domain reflectometer. The optical time-domain reflectometer includes a controller, a laser emitting apparatus, a signal modulation apparatus, a coupler, a signal coupling apparatus, and a receiver. The laser emitting apparatus outputs a first optical signal in a first time period. The signal modulation apparatus generates a pulse signal based on the first optical signal, and outputs the pulse signal to an optical fiber in a second time period, where the first time period includes the second time period. The receiver receives a scattered signal from the optical fiber, where a frequency of the scattered signal is the same as a frequency of the first optical signal. Then, the laser emitting apparatus outputs a second optical signal in a third time period, where a frequency of the second optical signal is different from the frequency of the first optical signal. The second optical signal may be used as a local oscillator signal to generate an interference effect with the scattered signal in the receiver, and the receiver implements coherent detection.
Patent EP-4172559-A1 (EP)
Inventor: KLOSE RALPH
IPC: G01B11/06
Filed: 2021-09-15
Abstract: Die Erfindung betrifft eine THz-Messvorrichtung (2) zur Vermessung eines Prüfobjektes (8), insbesondere eines Rohres (8), mit einem ersten THz-Transceiver (3), der einen ersten THz-Strahl (10) mit einer ersten Polarisationsebene entlang einer optischen Achse (A) durch einen Messraum (7) ausgibt, einen ersten Polarisations-Spiegel (4), der ausgebildet ist, den durch den Messraum (7) gelangten ersten THz-Strahl (10) entlang der optischen Achse (A) zurück zu dem ersten THz-Transceiver (3) zu reflektieren, einen zweiten THz-Transceiver (5), der einen zweiten THz-Strahl (11), der in einer von der ersten Polarisationsebene verschiedenen, insbesondere orthogonalen zweiten Polarisationsebene polarisiert ist auszugeben, einen zweiten Polarisations-Spiegel (6), der ausgebildet ist, den durch den Messraum (7) gelangten zweiten THz-Strahl (11) entlang der optischen Achse (A) zurück durch den Messraum (7) zu dem zweiten Transceiver (5) zu reflektieren, wobei die THz-Strahlen durch die jeweils anderen Polarisations-Spiegel ohne wesentliche Beeinflussung hindurchtreten, und die Messsignale (S1, S2) der THz-Transceiver (3, 5) zueinander in Beziehung gesetzt werden, um Schichtdicken (d1, d2) und/oder einen Brechungsindex (n) des Prüfobjektes (8) zu ermitteln.
Patent EP-4225221-A1 (EP)
Inventor: POINTILLART VINCENT
IPC: A61F2/30
Filed: 2021-09-21
Abstract: Disc prosthesis comprising an insert in the form of a flexible cushion, a first half-shell (10a) and a second half-shell (30a), the insert in the form of a flexible cushion being positioned between the half-shells, characterised in that a first of the half-shells (10a) comprises a first base provided with a first surface (12a) for hooking on to a first vertebra and a recessed annulus (15a) for forming a first cup (11a) and in that a second (30b) of the half-shells is provided with a first surface for hooking on to a second vertebra and a second surface bearing a rim (33a) surrounding a second cup (31a), the cups (11a, 31a) facing each other each receiving an upper crown (21) and a lower crown (23) of the insert, the annulus and the rim forming walls that slot together with play and making stops for angular and shearing movements between the half-shells.
Patent EP-4238133-A1 (EP)
Inventor: HOUSSAMEDDINE DIMITRI
IPC: G11C11/16
Filed: 2021-10-14
Abstract: L'invention concerne un dispositif de domaine magnétique dans lequel une couche libre magnétique (66, c'est-à-dire la couche de stockage) d'un pilier à jonction tunnel magnétique (MTJ) est à proximité immédiate d'une ligne d'écriture conductrice (62) qui est disposée en dessous du pilier à MTJ. Le dispositif de domaine magnétique comprend en outre une paire d'électrodes de fond (58) espacées, situées sous la ligne d'écriture conductrice et une électrode de dessus (72) située sur le pilier à MTJ. Le dispositif de domaine magnétique peut être utilisé dans des mémoires analogiques comprenant un stockage multibit, une mémoire analogique pour des applications d'intelligence artificielle (lA).
Patent EP-4203863-A1 (EP)
Inventor: RHODES CHEYENNE S
IPC: A61L27/58
Filed: 2021-08-26
Abstract: A bone implant (10) for enclosing bone material (12) is provided. The bone implant comprises a covering (18), which can be a biodegradable mesh. The covering is configured to be rolled into a diameter to at least partially enclose the bone material within the covering. In some embodiments, the covering includes a body portion (80) and a closure portion (82) adjacent to the body portion. The closure portion is configured to hold the covering in a rolled configuration to a predetermined diameter to at least partially enclose the bone material. A kit and a method of using the bone implant are also provided.
Patent EP-4120266-A1 (EP)
Title: Voice wake-up method and device
Inventor: LI CHUNJIAN
IPC: G10L25/51
Filed: 2021-04-12
Abstract: A speech wakeup method and device, and a readable storage medium are provided. The voice wakeup method includes: detecting voice signals that are input into at least two microphones and that meet a first condition; and determining, based on whether voice energy of the voice signals input into the at least two microphones meets a second condition, whether to wake up the electronic device; and if the second condition is met, waking up the electronic device; or if the second condition is not met, continuing to detect a voice signal input into the microphone. The electronic device can be woken up in a wakeup-keyword-free manner.
Patent EP-4218009-A1 (EP)
Title: Speaker identification accuracy
Inventor: FANG YEMING
IPC: G10L17/02
Filed: 2021-10-13
Abstract: A method (300) of generating an accurate speaker representation for an audio sample (202) includes receiving a first audio sample from a first speaker (10) and a second audio sample from a second speaker. The method includes dividing a respective audio sample into a plurality of audio slices (214). The method also includes, based on the plurality of slices, generating a set of candidate acoustic embeddings (232) where each candidate acoustic embedding includes a vector representation of acoustic features. The method further includes removing a subset of the candidate acoustic embeddings from the set of candidate acoustic embeddings. The method additionally includes generating an aggregate acoustic embedding (234) from the remaining candidate acoustic embeddings in the set of candidate acoustic embeddings after removing the subset of the candidate acoustic embeddings.
Patent EP-4251020-A1 (EP)
Inventor: SCHNEIDER MEINRAD
IPC: A47K10/48
Filed: 2021-11-22
Abstract: Die Erfindung stellt ein Handtrocknungssystem (100) umfassend eine Handtrocknungsvorrichtung, die ein Handtrocknungsgehäuse (10), das teilweise einen Innenraum (11) umschließt, in den über eine Eingangsöffnung (19) des Handtrocknungsgehäuses (10) eine Hand (2000) eines Benutzers teilweise oder ganz eingeführt werden kann, eine Einblasvorrichtung (20), die dazu eingerichtet ist, einen trocknenden Luftstrom zu erzeugen, der über mindestens eine Lufteinlassöffnung (24) derart in den Innenraum (11) eingeleitet wird, dass dieser über eine Handoberfläche einer in den Innenraum (11) eingeführten Hand (2000) des Benutzers strömt, und eine Absaugvorrichtung (30), die dazu eingerichtet ist, über mindestens eine Absaugöffnung (31) Luft aus dem Innenraum (11) abzusaugen, umfasst, gekennzeichnet durch eine mit der mindestens einen Absaugöffnung (31) verbundene, gegenüber einer Umgebung der Handtrocknungsvorrichtung luftdicht abgeschlossene Ableitvorrichtung, die dazu eingerichtet ist, die durch die Absaugvorrichtung (30) abgesaugte Luft in eine außerhalb des Handtrocknungssystems (100) angeordnete Auffangvorrichtung (1010) abzuführen, bereit.
Patent EP-4256722-A1 (EP)
Inventor: CHEEMA SHER ALI
IPC: H04B7/10
Filed: 2021-12-04
Abstract: Apparatuses, methods, and systems are disclosed for configuring a polarization type. One method (800) includes receiving (802) first configuration information from a network device for a serving cell. The first configuration information indicates at least one polarization type for downlink reception, for uplink transmission, or a combination thereof. The method (800) includes receiving (804) second configuration information from the network device for a handover procedure to a target cell. The second configuration information indicates at least one polarization type for downlink reception, for uplink transmission, or a combination thereof.
Patent EP-4256154-A1 (EP)
Inventor: MCCARTHY LUIS
IPC: E04G21/32
Filed: 2021-12-01
Abstract: A lapboard for a safety deck assembly, the safety deck assembly comprising a upper deck formed of one or more decking panels having a substantially planar upper surface and an elevated support assembly comprising a number of elongate legs, a base for each elongate leg to form a foot, a head for each elongate leg to at least partially support a decking panel relative to an upper end of the leg, the lapboard comprising a substantially planar upper surface and at least one receiving opening formed in an underside of the lapboard to receive a portion of the head to locate the upper surface of the lapboard substantially coplanar with the upper surface of the decking panels, the lapboard being smaller in width than the decking panels.
Patent EP-4171914-A1 (EP)
Inventor: MICHIELI MAXMILLIAN DAVID
IPC: B29B17/00
Filed: 2021-06-24
Abstract: A laminated transaction card may comprise a core layer comprising post-consumer polyethylene, a first support layer comprising polyethylene terephthalate glycol coupled to a first surface of the core layer by a first adhesive layer, and a second support layer comprising polyethylene terephthalate glycol coupled to a second surface of the core layer by a second adhesive layer. The first adhesive layer and the second adhesive layer may comprise an adhesive formulated to bond the post-consumer polyethylene and the support layers.
Patent EP-4169124-A1 (EP)
Title: Systems and methods for modular power amplifiers
Inventor: MONTEMURO ALBERT
IPC: H03F3/195
Filed: 2021-06-22
Abstract: Systems and apparatuses are disclosed that include an RF generator configured to generate RF signals having a wavelength. Amplifiers are configured to receive and amplify the RF signals from the RF generator and are separated from each other by a separation distance in a range between about 0.2 times the wavelength and about 10.0 times the wavelength. A power management system is configured to control one or more of the amplifiers based on information received that is associated with the RF signals.
Patent EP-4169960-A1 (EP)
Inventor: PARK JU YOUNG
IPC: A61L31/06
Filed: 2021-06-23
Abstract: The present invention relates to a shape memory polymer that can be restored to an original shape from a deformed shape by means of body temperature in the body. When using the shape memory polymer of the present invention and a device for wrapping the outer wall of blood vessels prepared thereby, it is possible to effectively prevent abnormal blood vessel dilatation, and prevent stenosis by effectively inhibiting neointimal formation.
Patent EP-4172774-A1 (EP)
Inventor: DISNEY TIM
IPC: G06F11/00
Filed: 2021-06-11
Abstract: Techniques are provided for detecting a malicious script in a web page. Instrumentation code is provided for serving to a client computing device with a web page. The instrumentation code is configured to monitor web code execution at the client computing device when a script referenced by the web page is processed. Script activity data generated by the instrumentation code is received. The script activity data describes one or more script actions detected by the instrumentation code at the client computing device. Prior script activity data generated by a prior instance of the instrumentation code is obtained. A malicious change in the script is detected based on comparing the script activity data and the prior script activity data. In response to detecting the malicious change in the script, a threat response action is performed.
Patent EP-4260392-A1 (EP)
Title: Batterie rechargeable à flux
Inventor: MAGAGNIN LUCA
IPC: H01M8/18
Filed: 2021-12-10
Abstract: L'invention concerne une batterie rechargeable à flux comprenant une première demi-cellule et une seconde demi-cellule, comprenant chacune un réservoir de travail dans lequel sont placés une électrode et un collecteur de courant, et un électrolyte étant amené à s'écouler à partir d'un réservoir externe, relié au réservoir de travail dans une configuration en boucle fermée. Les première et seconde demi-cellules sont séparées par un séparateur.
Patent EP-4263489-A1 (EP)
Inventor: SCHEIN-ALBRECHT KARIN
IPC: C07C227/18
Filed: 2021-12-16
Abstract: The present invention relates to a process of manufacturing 2-(4'-diethylamino-2'- hydroxybenzoyl)benzoic acid hexyl ester having a Gardner value of 8.2 or less comprising adjusting the reaction mixture obtained by reacting 2-(4'-diethylamino-2'-hydroxybenzoyl)benzoic acid with n-hexanol to a pH of more than 7 followed by extracting at least once with an aqueous phase and adsorbing the dissolved 2-(4'-diethylamino-2'- hydroxybenzoyl)benzoic acid hexyl ester over at least two different adsorbents.
Patent EP-4185329-A1 (EP)
Title: Complexes de ciblage de muscle et leurs utilisations
Inventor: SUBRAMANIAN ROMESH R
IPC: C12N15/113
Filed: 2021-07-09
Abstract: Des aspects de la divulgation concernent des complexes comprenant un agent de ciblage de muscle lié de façon covalente à une charge moléculaire. Dans certains modes de réalisation, l'agent de ciblage de muscle se lie spécifiquement à un récepteur de surface de cellule d'internalisation sur des cellules de muscle. Dans certains modes de réalisation, la charge utile moléculaire inhibe l'activité d'un allèle pathologique associé à une maladie musculaire. Dans certains modes de réalisation, la charge moléculaire est un oligonucléotide, tel qu'un oligonucléotide antisens ou un oligonucléotide d'ARNi.
Patent EP-4271434-A1 (EP)
Title: Breastmilk collection kit with optimized colostrum collection
Inventor: CHO DAVID Y
IPC: A61M1/06
Filed: 2021-12-22
Abstract: A colostrum collection container (208) includes a body (224) having a first opening (224a) configured to receive a breastshield and a second opening (224b) configured to be operatively coupled to a vacuum generator; a divider (228) sealingly disposed within the body; and an aperture (232) disposed on the divider. The divider (228) is disposed within the body and a first chamber (242) is disposed between the first opening and the divider, and a second chamber (246) is disposed between the divider and the second opening. The aperture (232) fluidly couples the first and second chambers, and a fluid flow path extends from the first opening (224a) through the aperture (232) and to the second opening (224b). So configured, a first fluid is collected in the first chamber (242) with gravity assistance while a second fluid flows through the fluid flow path from the first chamber to the second chamber (246).