baber/WOPTO huggingface dataset:
Patent NZ-517520-A (NZ)
Title: Benzamide formulation with histone deacetylase inhibitor activity
Inventor: ISHIBASHI MASAHIKO
IPC: A61K47/04
Filed: 2000-08-29
Abstract: There are provided pharmaceutical formulations with improved oral absorptivity and injections that contain, as active ingredients, high concentrations of benzamide derivatives and their pharmaceutically acceptable salts, which are useful as histone deacetylase inhibitors. A pharmaceutical solution is prepared by dissolving a benzamide derivative or a pharmaceutically acceptable salt thereof in an organic solvent and/or acidic liquid, and a pharmaceutical formulation is prepared by adding a surfactant, an acidic substance and/or a polyethylene glycol. The present invention has enabled dissolution of benzamide derivatives or their pharmaceutically acceptable salts at high concentrations, to prepare practical injections and oral liquid formulations and improve absorptivity with oral administration.
Patent NZ-523677-A (NZ)
Title: An arrangement and a method for interacting with an internal body organ
Inventor: AGERUP BENGT
IPC: A61M31/00
Filed: 2001-07-04
Abstract: An arrangement and a method for interacting with an internal body organ. The arrangement comprises a sheath in which at least two structural elements are inserted. The structural elements each have a proximal end and a distal end. The sheath has a proximal end and a distal end, the distal end being open. When the structural elements are displaced relative to the sheath they extend through the open distal end of the sheath and at least partly in the transverse direction away from the sheath for distending and/or expanding interaction between the distal end of each structural element and a body organ.
Patent NZ-528450-A (NZ)
Title: Novel, arylsulfonamide compounds for the treatment of obesity, type II diabetes and CNS-disorders
Inventor: CALDIROLA PATRIZIA
IPC: A61K31/495
Filed: 2002-05-08
Abstract: A compound of the formula (I) is described to be used in the manufacture of a medicament for use in the treatment or prophylaxis of obesity and/or type II diabetes. X is represented by the formula (Ia) or (Ib); Y is H, halogen, C1-6 alkyl, CF3, hydroxy, C1-6 alkoxy, C1-4 alkenyl; phenyl; phenoxy, benzyloxy, OCF3, CN, straight or branched C1-6 hydroxyalkyl, straight or branched C1-6 alkylhalides, NH2, NHR6, NR6R7, NO2, NHSO2R6, NR6COR7; R2 and R4 are independently -SO2R1, H, C1-6 alkyl, C1-C3 alkenyl, C1-C3 alkylaryl, Ar, -C(=O)R6, -C(O)NR6R7, -C(S)NR6R7, -CO2R6, -C(S)R6, straight or branched C1-6 hydroxyalkyl, straight or branched C1-6 alkylhalides; alternatively R2 and R4 are linked to form a group (CH2)2O, (CH2)4O, or (CH2)3-5 in formula (Ia); R5 is selected from the group consisting of the chemical groups such as formula (II) and (III). A process for the preparation of a compound of formula (I) is described to comprise: (a) introduction of a cyclic diamine into halogen and nitro substituted benzene under mild and basic conditions; (b) reduction of the nitro to the corresponding amine; (c) symmetric or asymmetric sulfonylation of the amine by a sulfonylchloride; (d) introduction of groups R3 and R4 by alkylation procedure in basic conditions.
Patent NZ-530484-A (NZ)
Title: Process and plant for the separation of undersirable substances from alimentary liquids, in particular from wine
Inventor: FERRARINI ROBERTO
IPC: B01D61/36
Filed: 2002-07-18
Abstract: Plant for the separation of undesirable substances from alimentary liquids, in particular from wine, which comprises a unit (3) with hydrophobic membranes (4) having holes (5) for trapping gas (G), supplied with wine to be treated (V) by means of first circulation means (6) and with an extraction fluid (L) having an alcoholic content substantially similar to that of the wine to be treated (V), by means of second circulation means (7). The two fluids pass along the two sides (4',4'') of the membranes (4), allowing the removal of the undesirable volatile substances which pass through the latter. The extraction fluid (L) is made to circulate by the second means (7) inside a purification circuit (8) which comprises a unit (9) for separation of the volatile substances, consisting preferably of an ion-exchange column. The process implemented in particular by the abovementioned plant envisages a step involving preparing the wine to be treated (V) inside a container (2), a subsequent step involving conveying to the abovementioned unit (3) and then a step involving removal of the undesirable volatile substances contained therein by means of evaporation, diffusion and consequent evaporation thereof which causes them to pass through the membranes (4) so as to be then evacuated by the extraction fluid (L) by means of ion-exchange resins, distillation, adsorption onto polymers or other system.
Patent NZ-532519-A (NZ)
Title: Omega-cycloalkyl 17-heteroaryl prostaglandin E2 analogs as EP2-receptor agonists
Inventor: BURK ROBERT M
IPC: C07D333/28
Filed: 2002-10-25
Abstract: Disclosed are compounds represented by formula I wherein the hatched segment represents an alpha bond, the solid triangle represents a beta bond, the wavy segment represents an alpha or beta bond, dashed lines represent a double bond or a single bond, X is selected from the group consisting of hydrogen and halogen radicals, R3 is heteroaryl or a substituted heteroaryl radical having a substituent selected from the group consisting of lower alkyl, OR4, CO2R4, halogen, CF3, COR4, COCF3, SO2, NR4, NO2 and CN, R1 and R2 are independently selected from the group consisting of hydrogen, lower alkyl radical having up to six carbon atoms, and a lower acyl radical having up to six carbon atoms, R is selected from the group consisting of CO2R4, CONR4, CH2OR4, CON R4SO2R4 P(O)(OR4) and an R4 substituted tetrazole wherein R4 is selected from the group consisting of H, phenyl and lower alkyl having from one to six carbon atoms, and n is 0 or an integer from 1 to 4 and the use of said compounds for the treatment of hypertension.
Patent NZ-536078-A (NZ)
Title: Knot tying aid
Inventor: CARNELL SEAN RICHARD
Filed: 2003-04-11
Abstract: A knot-tying device for manual tying of a knot in a knot in a flexible elongate material, comprises a short open-ended hollow cylinder having an upper end, a lower end and a shaped wall, the wall having an opening into the interior of the cylinder along a side in the form of a slot (105) between the upper end and the lower end, the wall having at least one short, outwardly extended portion forming a first, shallow external groove (312), the first groove (312) capable of being occupied by a side of a user's digit, the outer wall of the device including a second, circumferential outward-facing groove (305) near the upper end, the device can be held with one hand, and a flexible elongate material can be knotted using the device and the first and second grooves (312, 305) in the wall of the device as a guide when forming the knot.
Patent NZ-540423-A (NZ)
Title: Safety netting
Inventor: BISHOP DOUGLAS PAUL
Filed: 2005-05-30
Abstract: A wire netting in the form of a wire mesh formed from interconnected wires of 0.9 and 1.2 mm thickness. The wires form discontinuous lines of twisted wire junctions, with each junction formed from two twisted wires. A number of longitudinally-extending support wire arrangements are formed from the wires. Each support wire arrangement is affixed to the mesh to allow the netting to withstand a 165 kg human falling onto the netting from a height of 1400 mm. (61) Addition to 336890
Patent NZ-542116-A (NZ)
Title: Cooking apparatus
Inventor: TORRES GEORGES MAURICE
IPC: A47J37/12
Filed: 2003-04-29
Abstract: Cooking apparatus which comprises a double-walled housing constituted by inner and outer shells, there being a condensation chamber between the inner and outer shells of the housing and the outer shell of the housing being exposed to atmosphere so that it cools by radiation and convection, and which apparatus further comprises a fryer unit including a casing which defines a vessel for containing hot cooking oil, there being upper and lower sets of registering ports in the casing and in the inner shell of the housing whereby hot cooking vapours can escape from the fryer unit and into the condensation chamber via the upper set of ports and dewatered vapours can return via the lower set of ports.
Patent NZ-542906-A (NZ)
Title: Self adjusting tensioning device for endless chain using biased ratchet and pawl arrangement
Inventor: JARMAN DAVID
IPC: B27B17/08
Filed: 2004-07-13
Abstract: In order to adjust an endless chain 458 self adjusting device 450 consists of a primary block 466 mounting a steel compression plate 468 which with a threaded fastener (not shown) can be compressed to hold member 460 in place. On releasing plate 468 a biasing spring forces ratchet teeth past pawl 476.
Patent NZ-546582-A (NZ)
Title: Reclosable rigid container assembly with rim of lid covering only part of flanges and open central part of lid
Inventor: LONGO EUGENIO
IPC: B65D81/20
Filed: 2004-09-23
Abstract: A rigid or semi-rigid container assembly 10 is disclosed for the packaging of food products. The container assembly 10 comprises a support 20 and a frame 30. Support 20 comprises an outwardly extending peripheral flange 21 which is shaped to cooperate with frame 30 so that the frame can be snap-fit closed onto support 20. The rim 32 of frame 30 extends only over a fraction of flange 21 leaving part 22 of the flange and the central part (5) of support 20 uncovered. Also described is a method of packaging a food product and a package obtained by sealing a thermoplastic film (not shown) on the rim 32 of frame 30 and on part 22 of the flange of support 20 not covered by the rim 32 of the frame 30, wherein the film forms a first seal (not shown) with the rim 32 of the frame 30 and a second seal (not shown) with part 22 of the flange of support 20 not covered by the rim 32 of the frame 30.
Patent NZ-547606-A (NZ)
Title: A method for purification of metal based alloy and intermetallic powders or particles comprising introducing calcium vapour
Inventor: ZHANG DELIANG
IPC: B22F1/145
Filed: 2006-11-30
Abstract: Disclosed is a method of purifying a metal including the steps of: (a) placing the metal in powder form into a reaction apparatus; (b) introducing to the metal powder a suitable carrier substance which can suspend the powder particles; and (c) introducing a deoxidant calcium vapour into the reaction apparatus to create a reaction between the metallic powder and calcium vapour thereby removing inclusions in the metal.
Patent NZ-550857-A (NZ)
Title: 1,3,4-oxadiazol-2-ones as PPAR delta modulators
Inventor: MCGARRY DANIEL G
IPC: A61K31/4245
Filed: 2005-03-30
Abstract: Disclosed is a compound of formula I wherein ARYL is phenyl or pyridinyl, wherein said phenyl or pyridinyl is optionally substituted with one or more substituents selected from the group consisting of halogen, C1-6 alkyl, C1-6 alkenyl, C1-6 alkoxy, C1-6 perfluoroalkyl; C1-6 alkylthio, hydroxy, hydroxyC1-6 alkyl, C1-6 acyloxy, nitro, cyano, C1-6 alkylsulfonyl, amino, C1-6 alkylamino and C1-6 alkoxycarbonyl; W is a bond or (CH2)m, wherein m is an integer from 1 to 4; Z is -O(CH2)n-, -SO2(CH2)n-, -(CH2)n-Y-(CH2)n-,-(CH2)n-CO-, -O(CH2)n-CO- or -(CH2)n-Y-(CH2)n-CO- wherein Y is NR3, O or S and R3 is selected from the group consisting of H, C1-6 alkyl C3-8 cycloalkyl, C1-6 alkyl C3-8 cycloalkyl and benzyl and n is independently an integer from 1 to 5; X is NR3, O or S wherein R3 is as defined above; R1 is H, halogen, C 1-6 alkyl, C1-6 alkoxy, C 1-6 perfluoroalkyl; hydroxyC1-6 alkyl, nitro, cyano,and C1-6 alkylamino; and R2 is substituted or unsubstituted phenyl, pyridinyl or thienyl wherein the substituents are selected from the group consisting of halogen, C1-6 alkyl, C2-6 alkenyl, C1-4.alkoxy, C1-4 perfluoroalkyl, C1-6 alkylthio, hydroxy, hydroxyC1-6 alkyl, C1-4 acyloxy, nitro, cyano,C1-6 alkylsulfonyl, amino, C1-6 alkylamino and C1-6 alkoxycarbonyl; or a stereoisomer, tautomer or a solvate thereof or a pharmaceutically acceptable salt thereof. The compounds are selective ppARdelta ligand receptor binders, which are useful in modulating ppARdelta receptors for the treatment of diseases mediated by nuclear hormone receptors.
Patent NZ-565984-A (NZ)
Title: Method and apparatus for producing synergistic biocide
Inventor: SINGLETON FREDDIE L
IPC: A01N33/02
Filed: 2006-08-24
Abstract: Disclosed is a method for producing an aqueous solution containing a synergistic combination of monohaloamine and dihaloamine biocide to control growth of microorganisms in an aqueous system which comprises (a) contacting an ammonium or an amine source with a halogenated oxidant in water in amounts of each effective to produce monohaloamine, and (b) reducing the pH to convert a desired portion of the monohaloamine to dihaloamine.
Patent NZ-569923-A (NZ)
Title: Novel benzimidazole derivatives as vanilloid receptor 1 (VRL) inhibitors
Inventor: BESIDSKI YEVGENI
IPC: A61K31/4184
Filed: 2006-12-21
Abstract: Disclosed is a benzimidazole derivative of formula (I), where the substituents are as defined on the specification. Also disclosed is the use of the compound to treat VR1 mediated disorders such as acute or chronic neuropathic pain, acute and chronic nociceptive pain and acute or chronic inflammatory pain; and/or respiratory diseases; arthritis; osteoarthritis; rheumatoid arthritis; fibromyalgia; low back pain; post-operative pain; visceral pains like chronic pelvic pain; cystitis; irritable bowel syndrome (IBS); pancreatitis; ischeamic, sciatia, diabetic neuropathy, multiple sclerosis, interstitial cystitis and/or pain related to interstitial cystitis; HIV neuropathy; asthma; cough; chronic obstructive lung disease, specifically chronic obstructive pulmonary disease (COPD) and emphysema; lung fibrosis and interstitial lung disease; and/or inflammatory bowel disease (IBD); gastro-esophageal reflux disease (GERD); pain and other signs and symptoms associated with psoriasis; burn induced pain and/or inflammatory pain resulting from burn injuries; pain and other signs and symptoms associated with cancer; obesity and/or migraine; emesis; urinary incontinence; and/or hyperactive bladder, including signs and/or symptoms related to said diseases.
Patent NZ-573014-A (NZ)
Title: An off-axis ceiling or roof anchor assembly for hanging building services items with pivoting suspension members, and restraint systems for suspended components
Inventor: PANASIK CHERYL
IPC: F16B37/08
Filed: 2007-06-11
Abstract: An anchor assembly (110) for use with ceiling or roofing structures for hanging components, such as building services plant and ducting, or mechanical items. The assembly includes an anchor member (114) adapted to be fixedly mounted within a support surface, a hanger member (134) for suspending an object from the support surface and a connector structure interconnecting the hanger member and the anchor member. The anchor member is fixed using a threaded bolt to compress the anchor body thereby expanding and folding the wings (128) such as a rivet deforms in situ. The hanger member encloses the end of the anchor member and is pivotally movable with respect to a longitudinal axis of the anchor member, throughout a range of movement of substantially 0°-90° such that said hanger member will always be vertically plumb regardless of a particular angular inclination of the support surface upon which the anchor member is fixedly mounted. Threaded rod connected to a support structure or plant item can be screwed into the nut end of the hanger member (140)
Patent NZ-579095-A (NZ)
Title: Apparatus and method for automatically adjusting the sail surface exposed to the wind
Inventor: CAZZARO MICHELE
IPC: B63H9/10
Filed: 2009-08-17
Abstract: Reefing of a sail of a sail boat is performed by a motorized or servo assisted drive for hoisting or lowering or winding and unwinding at least part of the sail to control the area exposed to the wind. A programmed control unit, either automatically or following a command input by the crew, controls the operation of the drive in feedback based on at least one of the amplitude and/or frequency of rolling and/or pitching and/or yawing oscillations of the boat and/or the rolling and/or pitching and/or yawing accelerations of a portion of the boat, as detected by one or more detectors with respect to a reference system. The drive may operate a motorized mainsail furler, and motorized halyard winch, a motorized sheet winch, or reefing earing tensioner.
Patent NZ-581650-A (NZ)
Title: Hinged case having an internal compartment with a pivotable and slidable lid
Inventor: GRAHAM ROBERT
IPC: B65D1/24
Filed: 2009-12-04
Abstract: Disclosed is a container with a casing defining an interior storage region and a closure configured to selectively open and close a part of the storage region so as to respectively enable access to and storage of items contained therein. The closure is attachable to the casing along a first edge and is pivotable about a pivot axis defined by the first edge. The closure is slidable along the casing in a direction substantially parallel to the pivot axis between a closed position at which a second edge of the closure is locked to the casing, and an open position, at which the second edge is free of the casing. When the closure is in the open position and the second edge is free of the casing, the closure is free to pivot about the pivot axis.
Patent NZ-582680-A (NZ)
Title: Two pack package for smoking articles with connector hinged in at least two perpendicular directions
Inventor: LUTZIG BODO-WERNER
IPC: B65D5/42
Filed: 2008-07-18
Abstract: A container for smoking articles comprises at least two hingedly connected packs, each for housing a separate bundle of smoking articles. The container comprises a first pack having a first wall, a second pack having a first wall and a connector (10). The connector is hingedly coupled to the first wall of the first pack along a first fold line and hingedly coupled to the first wall of the second pack along a second fold line substantially perpendicular to the first fold line. The two hingedly connected packs may be hinged about either of the two perpendicular fold lines.
Patent NZ-582837-A (NZ)
Title: Methods and polynucleotides for altering tillering time in plants
Inventor: PUTHIGAE SATHISH
IPC: C07K14/415
Filed: 2008-07-25
Abstract: Disclosed is a method for producing plants with early or delayed tillering time. The method comprises transforming a plant cell or plant with: - a polynucleotide encoding a polypeptide with the amino acid sequence of SEQ ID NO: 1 or variant thereof having at least 70 percent sequence identity; or - a polynucleotide comprising the nucleotide sequence of SEQ ID NO: 12 or variant thereof having at least 70 percent identity. Early tillering time is effected by the over-expression of the polypeptide and delayed tillering time is effected by reduced expression of the polypeptide in the plant. Also provided are plants produced by the method.
Patent NZ-583578-A (NZ)
Title: Combination therapy for pancreatic cancer using an antigenic peptide and chemotherapeutic agent namely gemcitabine
Inventor: YAMAUE HIROKI
IPC: A61K38/00
Filed: 2008-08-19
Abstract: Disclosed is a an anti-cancer agent for treating cancer in a subject comprising (i) in combination with (ii); (i) one or more peptides inducing CTL selected from the group consisting of; (a) one or more peptides having the amino acid sequence selected from the group consisting of RFVPDGNRI (SEQ ID NO: 1), VYSSEEAEL (SEQ ID NO: 2), GYRIYDVVL (SEQ ID NO: 3), SYMISYAGM (SEQ ID NO: 4), KWEFPRDRL (SEQ ID NO: 5), and DFLTLEHLI (SEQ ID NO: 6), (b) the peptide of (a), in which 1, 2, or several amino acids are substituted, deleted, or added, and wherein said peptide has cytotoxic T cell inducibility; (c) the peptide of (b), wherein the second amino acid from the N-terminus is phenylalanine, tyrosine, methionine, or tryptophan; (d) the peptide of (b) or (c) , wherein the C-terminal amino acid is phenylalanine, leucine, isoleucine, tryptophan, or methionine; (e) one or more peptides having the amino acid sequence selected from the group consisting of AMFFWLLLV (SEQ ID NO: 7), VIAMFFWLL (SEQ ID NO: 8), AVIAMFFWL (SEQ ID NO: 9), KLIEIGVQT (SEQ ID NO: 10), YMISYAGMV (SEQ ID NO: 11), IQSDVWSFGV (SEQ ID NO: 12) and VLAMFFWLL (SEQ ID NO: 13); (f) the peptide of (e), in which 1, 2, or several amino acids are substituted, deleted, or added, and wherein said peptide has cytotoxic T cell inducibility; (g) the peptide of (f), wherein the second amino acid from the N terminus is leucine or methionine; and (h) the peptide of (f) or (g), wherein the C-terminal amino acid is valine or leucine, (ii) one or more chemotherapeutic agents selected from the group consisting of gemcitabine, a pharmaceutically acceptable salt thereof, and a prodrug thereof.
Patent NZ-583885-A (NZ)
Title: A detector circuit of a dimmer for detecting an overcurrent condition
Inventor: VANDERZON JAMES ROBERT
IPC: H02H3/08
Filed: 2008-09-19
Abstract: A detector circuit for detecting an overcurrent condition in a dimmer circuit for controlling power delivered to a load and a method for detecting an overcurrent condition in a dimmer circuit for controlling power delivered to a load is disclosed. The dimmer circuit has a first switch for controlling power to the load in a first polarity, where the first switch has a first anti-parallel diode, and a second switch for controlling power to the load in a second polarity, where the second switch has a second anti-parallel diode. The detector circuit comprises: means for applying to a comparator, a signal representative of a voltage drop across one of the first or second anti-parallel diodes, whichever is associated with a non-controlling one of the first switch or the second switch; and the comparator for comparing the applied signal with a reference voltage and generating a signal indicating a fault or overcurrent condition if the applied voltage exceeds the reference voltage.
Patent NZ-585592-A (NZ)
Title: Container with a sealable lid having a button, when the button is actuated a first time, the lid seal is caused to expand outwardly and engage the container wall and when actuated a second time, disengages the seal from the container wall
Inventor: MATSUMOTO TAMOTSU
IPC: B65D43/04
Filed: 2007-03-23
Abstract: A food storage device is disclosed. The food storage device comprises a container including an open-top wall structure that defines a receptacle for receiving material to be stored and a cover. The cover is disposable on the wall structure. The cover includes a top member that defines a cup having a bottom surface, where the bottom surface has a plurality of slots. A bottom member is positioned adjacent to the top member and a cam plate is connected to the bottom member. The cam plate includes at least two posts and a latch, where the posts are extendable through the slots of the cup. The latch includes two sides where the sides respectively define heart shaped cam surfaces. A seal is positioned between the upper member and the bottom member of the cover. A button, which includes a bottom surface, is slidably connected to the cover. A pair of pivot arms are positioned adjacent to the bottom surface of the button. Each of the pivot arms are pivotably connected to one of the posts of the cam plate. The pivot arms are connected to the posts after the posts are inserted through the slots of the bottom surface of the receptacle to connect the cam plate and the bottom member to the upper member. A pin is connected to the bottom surface of the button where the pin includes two opposing spaced apart arms. The arms are respectively engageable with the heart shaped cam surfaces of the latch. When the button is actuated a first time, the pivot arms move downwardly and the cam surfaces guide the arms of the pin to a locked position causing the seal to expand outwardly and engage the wall structure. When the button is actuated a second time, the cam surfaces guide the arms to an un-locked position, wherein the seal disengages the container and the pivot arms move upwardly against the bottom surface of the button to correspondingly move the button upwardly to a popped-up position. (62) Divided Out of 571198