baber/WOPTO huggingface dataset:
Patent IL-95477-A0 (IL)
Title: N-hydroxy-dibenz(b,e)oxepin-alkylamines and-alkanoic acid amides,related heterocyclic analogues,a process for their preparation and their use as medicaments
IPC: A61P25/04
Filed: 1990-08-23
Abstract: This invention relates to N-hydroxy-dibenz[b,e]oxepinalkylamines, N-hydroxy-dibenz[b,e]oxepinalkanoic acid amides and related heterocyclic analogues of the formula <CHEM> where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl, R<1> is hydrogen, loweralkyl, or acyl; R<2> is hydrogen, loweralkyl, cycloalkyl, arylloweralkyl or acyl; m is 0 or 1 and n is an integer of 0 to 12 and the pharmaceutically acceptable salts thereof. The compounds of this invention exhibit dermatological and analgesic activity.
Patent IL-96840-A0 (IL)
Title: Macrocyclic tetraaza compounds containing a six-membered ring,process for their production,and pharmaceutical agents containing the same
IPC: A61K31/435
Filed: 1990-12-31
Abstract: 6-Membered-ring-containing macrocyclic tetraaza compounds of the general formula I <IMAGE>  in which     ... represents a single or double bond,   Q represents a nitrogen atom or the radical NH,   X<1> represents a hydrogen atom, -(CH2)n-R<1>- or <IMAGE> group where     n denotes the figures 1 to 5,   m denotes the figures 0 to 2 and   R<1> denotes a hydrogen atom or a hydroxyl group,   X<2> represents X<1> or a -(CH2)n-(O)l-(CH2)k-(C6H4)q-R<2> group where     k denotes the figures 0 to 4,   l and q denote the figures 0 or 1 and R<2> denotes a hydrogen atom, a C1-C4-alkoxy group, a functional group or, bonded by means of this functional group, a bio- or macromolecule,   A<1>, A<2>, B<1>, B<2>, C<1>, C<2>, D<1>, D<2>, E<1>, E<2>, F<1> and F<2> independently of one another each represent X<2> G represents R<2> or a second macrocycle, bonded by means of K, of the general formula II <IMAGE> where K denotes a direct bond, a bis(carbonylamino) group (-NH-CO-CO-NH-) or a C1-C14-alkylene group which optionally at the ends carries carbonyl( &rdurule& CO) or carbonylamino (-NH-CO-) groups or oxygen atoms and optionally contains one or more oxygen atom(s), hydroxymethylene (-CH-OH-), CH(X<2>)COOZ, acyl or hydroxyacyl- substituted imino groups or one or two C-C double and/or C-C triple bonds, Z represents a hydrogen atom and/or a metal ion equivalent of an element of atomic number 21-29, 31, 32, 37-39, 42-44, 49 or 57-83, with the proviso that the 12 ring substituents A<1> to F<2> represent at least 8 hydrogen atoms, that X<1> and X<2> only simultaneously represent hydrogen atoms when at least one of the ring substituents A<1> to F<2> does not represent a hydrogen atom and that the macrocycle of the general formula I no longer contains a bio- or macromolecule and that, if desired, the radical of the CO2H groups is present as ester or amide, and their salts with inorganic and/or organic bases, amino acids or amino acid amides are useful diagnostic and therapeutic agents.
Patent FI-20001617-A0 (FI)
Inventor: LAENSIOE JARI
IPC: H04L29/06
Filed: 2000-07-06
Abstract: The invention relates to implementing data transmission between at least two sets of software used in one or more devices which comprise means for establishing a connection to a telecommunications system. The communication is partly carried out with method calls including a service request. A service broker supplies the service request included in the method call to indicated server, which responds to the method call by sending required information back to the sender of the method call via the service broker. At least some of the programs participating in data transmission are implemented with a script-based programming language in the devices. The arrangement comprises an application which transmits service requests and responses to the requests between the service broker and the software that needs data transmission, and renders data transmission requests and responses to the requests compatible between script-based software and another system.
Patent FI-20031165-A0 (FI)
Inventor: MAANIITTY JUSSI
IPC: H04M1/7243
Filed: 2003-08-18
Abstract: The invention relates to a method for selecting a data transfer method in a telecommunication system wherein several data transfer methods exist for selection. The method comprises determining a message to be transmitted on the basis of inputs received from a user. At least one piece of property information concerning the message being entered or already entered is checked. In order to transmit the message, the data transfer method associated in predetermined selection conditions with the property information is selected.
Patent IL-100585-A0 (IL)
Title: Use of human igf-i
IPC: A61K38/30
Filed: 1992-01-05
Abstract: The invention discloses the use of human IGF-I or effective analogues thereof for the manufacture of a medicament for prevention or treatment of cardiac disorders. More specifically the medicament is used for the promotion of cardiac muscle protein synthesis, for prevention or treatment of cardiomyopathies, acute heart failure or acute insult including myocarditis or myocardial infarction and for improving of cardiac output by increasing heart stroke volume e.g. for treatment of myocardial infarction. The invention also discloses a composition comprising human IGF-I or effective analogues thereof together with additional proteins or peptides such as other growth factors, hormones, binding proteins or receptors for enhancing or improving the desired effect(s) of IGF-I or its effective analogues and possibly pharmaceutically acceptable carrier or diluent for the prevention or treatment of cardiac disorders.
Patent IL-100873-A0 (IL)
Title: Glyphosate compositions and their use
IPC: A01N25/30
Filed: 1992-02-05
Abstract: A composition of glyphosate comprising a glyphosate herbicide and a surface active component characterized in that the said surface active component is the combination of a sorbitan fatty acid ester and a surfactant chemically different from said sorbitan fatty acid ester.
Patent IL-103898-A0 (IL)
Title: Process for preparing 2-substituted 4,6-dialkoxy-pyrimidines and certain 2-n-alkylamino-4,6-dialkoxy-pyrimidines
IPC: C07D239/54
Filed: 1992-11-26
Abstract: A novel process for the preparation of 2-substituted 4,6-dialkoxypyrimidines is described, in which a cyanoimidate of the general formula 
<IMAGE>
 is subjected to a cyclization reaction with a hydrogen halide to give a halopyrimidine derivative, which is then converted with compounds of the formula
 M-R3 or
 
<IMAGE>
 to give the end product of the general formula 
<IMAGE>
 where R1 and R2 are identical or different and denote a C1-C4-alkyl group, R3 denotes an R4-O- or R4-S- group or 
<IMAGE>
 group, in which R4 denotes a C1-C4-alkyl group and R5 denotes a hydrogen atom, a C1-C4-alkyl group or a phenyl group.
Patent IL-111051-A0 (IL)
Title: Sphagnum moss composition for the production of sheeted absorbent and method for evaluating the potential of sphagnum moss material for absorbing liquid
IPC: A01H11/00
Filed: 1994-09-23
Abstract: A method for selectively harvesting vegetable raw material from a sphagnum moss growing site for use in manufacturing liquid-absorbent structures, said growing site containing an aggregate of sphagnum moss species that predominantly belong to a group of botanical sections consisting of PALUSTRIA, ACUTIFOLIA, RIGIDA, SUBSECUNDA and CUSPIDATA.
Patent IL-111693-A0 (IL)
Title: Methods of isolating hepatoblasts
IPC: G01N33/50
Filed: 1994-11-18
Abstract: This invention relates to methods of isolating hepatoblasts utilizing panning techniques and fluorescence activated cell sorting. This invention further relates to isolated hepatoblasts and to a method of treating liver dysfunction as well as to methods of forming artificial livers.
Patent IL-113658-A0 (IL)
Title: Method for recognizing handwritten input
IPC: G06V30/10
Filed: 1995-05-08
Abstract: The present invention determines whether two discrete continuous segments of handwritten input S1 (210) and S2 (220) form part of the same handwritten input or are part of more than one, separate handwritten inputs. The present method calculates one or more substantially parallel distance disposed substantially parallel to the writing access (210) and compares these distances to one or more predefined thresholds. The predefined thresholds specify minimum distance measures which must be exceeded by the substantially parallel distances for the discrete continuous segments to be judged as belonging to separate segments of handwritten input.
Patent IL-134745-A0 (IL)
Title: Device for sealing a system for conditioning products on a palette
IPC: B65D81/18
Filed: 1998-07-30
Abstract: A series of flexible sheets are used around a pallet with products thereon, the pallet being disposed in a tunnel. The flexible sheets fill with air pressure supplied at one end of the tunnel such that air leakage around the periphery of the pallet and products is prevented. The arrangement is used to maintain the products at desired temperatures.
Patent IL-145068-A0 (IL)
Title: The use of glycine betaine to prepare a pharmaceutical composition
IPC: A61K31/205
Filed: 2000-03-01
Abstract: Pharmaceutical uses of glycine betaine, such as for the treatment of thromboses not induced by hyperhomocystenemia or homocystinuria, of blood disorders, such as blood coagulation, thrombi formation.
Patent IL-147493-A0 (IL)
Title: Methods for reducing the formation of byproducts in the production of recombinant polypeptides
IPC: C12P21/02
Filed: 2001-05-10
Abstract: A method for reducing the formation of a byproduct polypeptide containing an O-acetylserine residue in place of a serine residue by adding at least one of histidine, methionine or glycine to the medium in a method for producing a polypeptide containing a serine residue by culturing transformed cells, and a method for producing a polypeptide containing a serine residue by culturing transformed cells, characterized by reducing the formation of a byproduct polypeptide containing an O-acetylserine residue in place of a serine residue by adding at least one of histidine, methionine or glycine to the medium.
Patent IL-157408-A0 (IL)
Title: Calcium supplementation to reduce prostate cancer risk
IPC: A61K31/194
Filed: 2002-02-14
Abstract: A method for promoting prostate helath in a subject comprising administering a dose of calcium to the subject.  Particularly provided is a method for reducing the risk of prostate carcinomas, comprising administering a dose of elemental calcium effective to reduce the risk of prostate cancer.  In an example, 1200 mg of elemental calcium (supplied in 3000 mg of calcium carbonate) administered twice daily resulted in decreased risk of prostate cancer.
Patent IL-160289-A0 (IL)
Title: Modified transferrin fusion proteins
IPC: C07K19/00
Filed: 2002-08-30
Abstract: Modified fusion proteins of transferrin and therapeutic proteins or peptides with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
Patent IL-165250-A0 (IL)
Title: Methods of donor specific crossmatching
IPC: G01N33/569
Filed: 2003-05-16
Abstract: The detection of endothelial cell antibodies has been proven clinically important for successful organ transplantation. Disclosed are methods of isolating Tie-2+ and CD34− precursor endothelial cells for use in donor-specific crossmatching.
Patent IL-179400-A0 (IL)
Title: Purine derivatives as adenosine a1 receptor agonists and methods of use thereof
IPC: C07H19/12
Filed: 2006-11-20
Abstract: The invention relates to Purine Derivatives, compositions comprising an effective amount of a Purine Derivative; and methods for reducing an animal's rate of metabolism, protecting an animal's heart against myocardial damage during cardioplegia; or for treating or preventing a cardiovascular disease, a neurological disorder, an ischemic condition, a reperfusion injury, obesity, or wasting disease, or diabetes, comprising administering an effective amount of a Purine Derivative to an animal in need thereof.
Patent IL-185589-A0 (IL)
Title: Coating compositions for marking substrates
Filed: 2007-08-29
Abstract: The present invention provides coating compositions for marking substrates, which comprises a color former, an amine salt of an organic metal compound, a binder, a solvent, and optionally additional components, wherein the amine salt of the organic metal compound is of formula (I) in which X is silicon or boron, and E and F are the same or different and are selected from the group consisting of a, b, c, d, e, f, g, h in which R6 and R7 are the same or different are hydrogen, C1-4-alkyl, C1-4-alkoxy, halogen, amino or carboxy, and for X=silicon o=1 and p=0, and R1 is aryl, aralkyl or C1-4-alkyl, or o=1 and p=1, and R1 and R2 together form a one residue selected from the group consisting of a, b, c, d, e, f, g and h, and for X=boron o=0 and p=0, and R3, R4 and R5 are the same or different and are hydrogen, C1-12-alkyl, C1-6-hydroxyalkyl, allyl, aralkyl or arylsulfonyl, in which aralkyl or arylsulfonyl can be substituted with C1-4-alkyl, or R3 and R4 together with the nitrogen to which they are attached form a morpholino or piperidino ring. The present invention also provides a process for the preparation of the composition of the present invention, substrates coated with these compositions, a process for preparing coated substrates, a process for preparing a marked substrate using these compositions, a marked substrate obtainable by the latter process and amine salts of the organic metal compounds of formula I.
Patent IL-202822-A0 (IL)
Title: A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
Filed: 2009-12-17
Abstract: The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.
Patent RO-127938-A0 (RO)
Title: Mineral premix for feeding egg-laying hens
Inventor: CRISTE RODICA DIANA
IPC: A23K1/18
Filed: 2012-03-30
Abstract: The invention relates to a mineral premix for feeding egg-laying hens. According to the invention, the premix comprises 1400 mg/kg of inorganic manganese, 2800 mg/kg of inorganic iron, 200 mg/kg of inorganic copper, 1650 mg/kg of inorganic zinc, 50 mg/kg of cobalt as cobalt chloride, 114 mg/kg of iodine as potassium iodide, 18 mg/kg of selenium as sodium selenite, 1400 mg/kg of manganese as organometallic compounds, 2800 mg/kg of iron as organometallic compounds, 200 mg/kg of copper as organometallic compounds and 1650 mg/kg of zinc as organometallic compounds.
Patent ZW-9487-A1 (ZW)
Title: Sealed documents and methods of making and using same
Inventor: WALTER GRAHAM GREIG
IPC: B41L1/22
Filed: 1987-05-26
Abstract: Sealed documents are provided by placing an area or areas of reusable adhesive (26) on one side of a sheet of paper (10) or the like, and twice folding the document to seal same along one edge, or thrice folding the document along all edges. Multiple plied sheets (10a, 10b and 10c) may be manipulated in like manner.
Patent IE-910700-A1 (IE)
Title: 3-arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions
Inventor: WARD SUSAN JEAN
IPC: C07D405/06
Filed: 1991-03-01
Abstract: Antiglaucoma compositions containing 3-arylcarbonyl-1-aminoalkyl-1H-indoles, as the active component thereof, and a method of use thereof in the treatment of glaucoma. Also included are novel 3-arylcarbonyl-1-aminoalkyl-1H-indoles.
Patent MA-22814-A1 (MA)
Inventor: HOLGER HEITSCH
IPC: C07D233/84
Filed: 1993-03-05
Abstract: Compounds of the formula (I) <IMAGE>  in which     R<1> is, for example, ethyl,   R<2> is, for example, methyl,   n is, for example, zero,   R<3> is, for example, COOH and   R<4> is, for example, SO2NHCONHCH3 are highly active antagonists of angiotensin II receptors.
Patent MA-26699-A1 (MA)
Inventor: SANDRA MARINA MONAGHAN
IPC: A61P31/04
Filed: 1999-10-13
Abstract: The present invention provides compounds of formula (I):and pharmaceutically acceptable salts and solvates thereof, together with processes for the preparation of, compositions containing, uses of and intermediates used in the preparation of such compounds that have A2a receptor agonist activity.
Patent MA-40081-A1 (MA)
Title: Dispositif pour le montage et le raccordement d'un article sanitaire à une paroi.
Inventor: GNUTTI GIULIANO
IPC: E03C1/04
Filed: 2017-02-09
Abstract: Un dispositif (100) pour le montage et le raccordement de robinetterie à une paroi comprend un raccord (2), muni d'une partie arrière (21) pour la connexion avec un conduit sanitaire et d'une partie avant (22) pour la connexion avec robinetterie, et une plaque (1), pour la connexion à une paroi et munie d'au moins un trou passant (12) adapté pour recevoir au moins partiellement la partie avant (22) du raccord (2). Le dispositif (100) comprend en outre des moyens anti-rotation pour éviter la rotation du raccord (2) par rapport à la plaque (1). Lesdits moyens sont obtenus par l'engagement mécanique d'au moins une dent (215), prévue sur le raccord (2), insérée dans un siège (123) défini entre deux éléments d'arrêt (124) prévus sur la plaque (1), dans lequel le siège (213) est réalisé sur un plan transversal par rapport à la plaque (1).
Patent MA-55435-A1 (MA)
Title: Mécanisme d’Oscillation sur Toute Interaction entre les Corps et les Charges pondérales
Inventor: Idriss KANIA
IPC: A45F3/04
Filed: 2022-02-03
Abstract: Le mécanisme d’oscillation pondérale est un système qui permet de mettre en oscillation une masse (m) solide, liquide ou gazeuse quel que soit son orientation (verticale, horizontale ou transversale) générant ainsi un mouvement pondérale dans un plan à deux (2) dimensions ou dans un espace à trois (3) dimensions. Cette innovation permet la réduction de la charge pondérale de tout objet relié à ce mécanisme et permet ainsi de porter des charges supérieures. Ce mécanisme est réalisable : 1. Avec un ressort mécanique ou plusieurs ressorts mécaniques. 2. Avec un ressort mécanique ou plusieurs ressorts mécaniques faits de fils ronds de différente rigidité. 3. Avec un ressort mécanique ou plusieurs ressorts mécaniques fait de lamentes plates de différente rigidité. 4. Avec un ou plusieurs vérins pneumatiques 5. Avec un ou plusieurs vérins pneumatiques à simple effet. 6. Avec une ou plusieurs vérins pneumatiques à double effet. 7. Avec tout système d’oscillation à base d’air comprimé. 8. Le fonctionnement du mécanisme d’oscillation pondérale est réalisable en intégrant, au système d’oscillation, tout système de poulie, palan ainsi que tout autre objet remplissant les mêmes fonctions que les systèmes prés cités.
Patent UY-24367-A1 (UY)
Title: Vacunas contra tumores y procedimiento para su produccion
Inventor: SCHMIDT WALTER
IPC: A61K35/12
Filed: 1996-11-19
Abstract: Vacuna contra tumores y procedimientos para su producción. La vacuna contra tumores contiene células tumorales de las que al menos una parte presenta por lo menos un haplotipo MHC-I del paciente en la superficie de la célula y que se cargaron con uno o varios péptidos que se fijan a la molécula de MHC-I, de modo que las células tumorales son reconocidas como extranas en el contexto con los péptidos del sistema inmune del paciente y desencadenan una respuesta inmune celular. La carga se efectúa en presencia de un policatión tal como polisina
Patent UY-24452-A1 (UY)
Title: Complejo de construccion combinado de vivienda, habitat marino, y educacional
IPC: E04H3/00
Filed: 1997-01-30
Abstract: Complejo de construcción edificada en tierra, que tiene dos divisiones distintivas cada una en combinación con una contención adyacente de agua. Una primera división incluye una pluralidad de unidades y una segunda división incluye corredores de exhibición u otros salones públicos para su utilización con exhibiciones del tipo para museo. Cada división está arreglada en combinación con la estructura de contención de agua por medio de la cual visitantes públicos pueden entrar a la segunda división y se les proporciona acceso para observar la vida marina que reside dentro de la estructura de contención de agua y explorar las exhibiciones y demostraciones de la segunda división, mientras que los ocupantes de a primera división se les proporciona lo último en asociación cercana con la vida marina residente dentro de la estructura sin el inconveniente del flujo de tráfico de los visitantes públicos.
Patent UY-25326-A1 (UY)
Title: Un proceso para la introducción de aditivos y coadyuvantes para el envasado de bebidas en contenedores plásticos
Inventor: HERMINIO MORETTI ROBERTO
Filed: 1998-12-23
Abstract: Proceso para introducción de aditivos y coadyuvantes para envasado de bebidas en contenedores plásticos caracterizado porque su formulación contiene: uno o más complejos enzimáticos; uno o más agentes preservativos y opcionalmente, otros aditivos para los alimentos asociados a un post tratamiento térmico especialmente desarrollado para resultar efectivo en la estabilización microbiológica pero lo suficientemente suave a fin de precaverse de danos al contenedor plástico. En particular los complejos enzimáticos comprenden principalmente dos enzimas: glucosa oxidas y catalasa, además de preservativos de la familia de los parabenos. Se incluye el proceso que incluye dosificar los aditivos y coadyuvantes antes del tratamiento térmico, u otro que comprende dosificar los aditivos y coadyuvantes durante el proceso de filtración, o un tercero que comprende dosificar los aditivos ants del tratamiento térmico y los coadyuvantes después del mismo.
Patent UY-27848-A1 (UY)
Title: Derivados de heteroarilamida benzocondensada de tienopiridinas utiles como agentes terapeuticos, composiciones farmaceuticas que incluyen a los mismos, y metodos para su uso.
Inventor: ROMINES WILLIAM HENRY
Filed: 2003-06-13
Abstract: La invención se refiere a compuestos representados por la fórmula I y a sus profármacos o metabolitos, o sales o solvatos farmacéuticamente aceptables de dichos compuestos, dichos profármacos y dichos metabolitos, en la que Z, Y, R11 y R14 , R15 , R16 , R17 son como se definen aquí. La invención se refiere también a composiciones farmacéuticas que contienen los compuestos de fórmula I y a métodos par tratar trastornos heperproliferativos en un administrando los compuestos de fórmula I.
Patent UY-28205-A1 (UY)
Title: Formulaciones farmaceuticas que comprenden un nuevo agente enmascarante de la amargura.
Inventor: FUJITA HIKARU
IPC: A61K9/00
Filed: 2004-02-25
Abstract: El presente invento se refiere a un nuevo agente enmascarante de la amargura para formulaciones farmacéuticas que van a aplicarse oralmente. Se encontró que ciertos tensioactivos farmacéuticamente aceptables pueden enmascarar el sabor amargo de algunos compuestos farmacéuticamente activos que saben amargos. El presente invento afecta en particular a formulaciones que comprenden epinastina o quinina.
Patent UY-29307-A1 (UY)
Title: Composición que comprende una epotilona y métodos para producir dicha composición
Inventor: SACHSE ANDREAS
IPC: A61K9/08
Filed: 2005-12-22
Abstract: Métodos para producir formulaciones farmacéuticas de epotilonas apropiadas para administrar por vía parenteral, tal como por vía intravenosa.
Patent UY-29606-A1 (UY)
Title: Derivados de n-(piridin-2-il)-sulfonamida
Inventor: NAIR SAJIV KRISHNAN
IPC: A61P3/04
Filed: 2006-06-16
Abstract: La presente invención se refiere a nuevos compuestos, a composiciones farmacéuticas que comprenden los compuestos descritos en la presente, sus sales farmacéuticamente aceptables, hidratos y solvatos, así como al uso de los compuestos en medicina y para la preparación de un medicamento que actúa en la enzima 11-B(Beta)-hidroxiesteroide deshidrogenasa humana de tipo 1 (11B(Beta)HSD1).