baber/WOPTO huggingface dataset:
Patent CA-2480763-A1 (CA)
Title: Compositions and methods for dosing liposomes of certain sizes to treat or prevent disease
Inventor: RODRIGUEZA WENDI V
IPC: A61K38/00
Filed: 2003-04-04
Abstract: The present invention relates to pharmaceutical compositions comprising liposomes and methods of using such liposomes to prevent, treat, or manage a variety of diseases and/or bodily conditions. The liposomes may comprise large unilamellar vesicles (LUVs) alone or in combination with multilamellar vesicles (MLVs), small unilamellar vesicles (SUVs), or other therapeutics. The invention relates to liposomes having certain diameters administered to patients using specific doses and/or dosing regimens.
Patent CA-2480855-A1 (CA)
Inventor: PEACE BENJAMIN NORMAN
IPC: H01M8/24
Filed: 2003-03-27
Abstract: A fuel cell compression assembly provides a method for applying and retaining compression to a fuel cell stack through the use of a fixed carriage into which the cells can be built directly. The assembly comprises: a carriage unit having at least two opposing side walls maintained in spaced relation by a base member extending therebetween at a lower position on the sides, the opposing side walls and base member thereby defining a cradle for receiving fuel cell plates, the opposing side walls each including at least one engagement member on internal face for engaging with a top closure member forming the top of the carriage unit. The closure member is adapted to close the carriage unit and apply pressure to the plates therein, by automatic locking engagement with the cradle when the closure member is brought into position with the cradle in a first direction substantially orthogonal to the plane of the plates.
Patent CA-2483420-A1 (CA)
Title: Bio-spectral imaging system and methods for diagnosing cell disease state
Inventor: COLLINS WILLIAM S II
IPC: A61B19/00
Filed: 2003-04-25
Abstract: A bio-spectral imaging system and methods for in situ diagnosis of a disease state in biological tissue or cells of a living organism are provided. In on e form, a method includes applying to the tissue or cells in situ a biological stain composition that includes at least one metachromatic dye; performing a spectral analysis to obtain at least one spectrum of the stained tissue or cells; comparing the spectrum with spectra from a library of spectra of similarly stained reference tissue or cells that have been categorized as diseased or non-diseased; and correlating the spectrum to a disease state. T he system and methods may be used to diagnose, for example, pre-cancer and/or cancer, as well as diseases caused by various microorganisms. Methods for creating a library of spectra, methods for monitoring the efficiency of photodynamic therapy of diseased biological tissue or cells in vivo, as well as methods for improving the efficiency of photodynamic therapy are also provided.
Patent CA-2483557-A1 (CA)
Inventor: FRIEND KEITH
IPC: A61K38/27
Filed: 2003-04-25
Abstract: Methods of treating, preventing or delaying onset of a neoplasm comprise administering to an individual an anti-neoplastic agent and a growth hormone receptor antagonist. Methods for reducing tumor weight or volume comprise administering to an individual an anti-neoplastic agent and a growth hormone receptor antagonist. Compositions comprise an anti-neoplastic agent and a growth hormone receptor antagonist.
Patent CA-2484627-A1 (CA)
Inventor: WILLS IVAN NICHOLAS
IPC: A61K35/545
Filed: 2003-05-30
Abstract: L'invention concerne un appareil de récupération de particules spécifiques ayant des propriétés prédéterminées, à partir d'un certain nombre de particules. L'appareil comprend un système de stimulation, un système de détection, un système de récupération et un système de contrôle. A l'utilisation, le système de contrôle active le système de stimulation pour tenter de stimuler une ou plusieurs particules, cette opération étant suivie de la détection d'au moins une particule stimulée, par le système de détection. La détection est suivie de la récupération de particule, assurée par le système de récupération.
Patent CA-2485416-A1 (CA)
Inventor: KAWAKAMI KOJI
IPC: G01N33/10
Filed: 2003-04-07
Abstract: Cereal grains are put into a test tube containing a specific reagent solution and stirred. The thus obtained reaction solution is introduced into a cell.  Then the cell is irradiated with light and the absorbance at a wavelength showing the peak absorbance and the absorbance within a wavelength in which the absorbance scarcely changes are detected. Based on the difference between these absorbance values, the freshness of cereal grains or beans is judged.
Patent CA-2489283-A1 (CA)
Inventor: BRISCO DAVID PAUL
IPC: E21B43/10
Filed: 2003-06-12
Abstract: An apparatus (910) for radially expanding and plastically deforming an expandable tubular member (66) includes a collapsible expansion cone (44, 46).
Patent CA-2489765-A1 (CA)
Inventor: BASSLER PETER
IPC: C07D301/32
Filed: 2003-07-23
Abstract: Procédé appliqué en continu de distillation pure d'oxirane obtenu lors de la synthèse d'oxirane par mise en réaction d'un hydroperoxyde avec un composé organique. Ledit procédé est caractérisé en ce que l'oxirane brut est séparé dans une colonne de distillation à paroi de séparation en une fraction à point d'ébullition bas, une fraction à point d'ébullition moyen et une fraction à point d'ébullition élevé et en ce que l'oxirane est prélevé par extraction latérale en tant que fraction à point d'ébullition moyen à une concentration d'au moins 99,9 %.
Patent CA-2492378-A1 (CA)
Title: Modified amino acid for the inhibition of platelet aggregation
Inventor: AZRIA MOISE
IPC: A61K38/28
Filed: 2003-07-16
Abstract: A method of inhibiting blood platelet aggregation in a mammal is provided. T he method comprises the administration of a platelet aggregation inhibiting amount of a modified amino acid or pharmaceutically acceptable salt thereof.
Patent CA-2494022-A1 (CA)
Title: Agent de detection de malondialdehyde, procede de production de cet agent et kit de detection
Inventor: ABELS ROBERT D
IPC: G01N33/493
Filed: 2003-07-29
Abstract: L'invention concerne un réactif destiné à détecter la présence d'aldéhyde en particulier dans une solution aqueuse, ou dans d'autres liquides corporels, comprenant une solution de métabisulfite de sodium, de l'acide phosphorique, de la fuschine basique (BA130) et de l'eau déionisée. Les quantités respectives sont de 8 à 12 grammes de métabisulfite de sodium, 10 millilitres d'acide phosphorique, 4,8 à 5,2 grammes de fuschine basique et 995 à 1005 millilitres d'eau déionisée. L'invention concerne aussi un kit de détection comprenant un boîtier étanche contenant une quantité déterminée de réactif, un distributeur permettant d'obtenir une quantité déterminée d'échantillon à tester et le disposant dans le boîtier et une carte de couleurs destinée à comparer la couleur du réactif combiné à l'échantillon après une période d'attente de 2 à 5 minutes. L'invention concerne encore un procédé de fabrication du réactif consistant à combiner les ingrédients et à les mélanger au moins 10 minutes puis à ajouter 28 à 32 grammes d'un charbon d'os animal et à bien agiter le mélange et à le laisser reposer au moins 24 heures, et jusqu'à 36 heures. Par la suite, on élimine le charbon d'os et le pH de la solution décolorée est ajusté entre 1,75 et 1,93 par addition lente d'acide phosphorique tout en agitant bien la solution.
Patent CA-2496602-A1 (CA)
Inventor: FAYETTE THIBAULT
IPC: A47L11/03
Filed: 2003-09-09
Abstract: The present invention provides an actuating device (10) suitable for remotely actuating a tool which can be the fluid delivery mechanism of a cleaning implement. The actuating device has a flexible tape (20) attached at one end to a spring-loaded spool mechanism (30, 40) connected to a trigger (50) where the spring loaded spool mechanism is located within a housing (60) for holding the device. The tape is threaded through at least one pole segment (70) and is attached to a tool which can be actuated by a pulling or pushing motion of the tape. The present invention also provides a pair of electric cables (120, 220) which are attached at one end to the spring-loaded spool and at the other end to an electric tool or device such as a motor for driving a pump. An electric switch (55), which is located on the housing (60) of a pistol-grip, is used to close the electric circuit formed by the pair of cables.
Patent CA-2496882-A1 (CA)
Title: Metering valve for a metered dose inhaler providing consistent delivery
Inventor: HODSON PETER D
IPC: A61M11/00
Filed: 2003-09-04
Abstract: The present invention relates to a novel design for a metering valve that provides improved consistency of formulation delivery. Generally, the metering valve includes (a) a valve stem that generally defines a longitudinal axis and includes a body portion having a metering surface, wherein the longitudinal axis and a plane tangential to at least a portion of the metering surface define an angle from about 2~ to about 90~; and (b) a valve body having an internal chamber defined at least in part by the body wall and includes a metering portion configured to substantially conform to the metering surface of the valve stem.
Patent CA-2497194-A1 (CA)
Inventor: BRIGHTWELL LIONEL
IPC: E04C3/16
Filed: 2005-02-16
Abstract: A wood containing, open web trimmable truss assembly composed of opposed chord members defining an open web central structure that is bounded at each ends by a closed, trimmable end block. The open web central structure is formed by a plurality of web elements attached to the chord members via a mortise and tenon coupling.  The trimmable end block is attached to both chord members and the outer most web element.
Patent CA-2502331-A1 (CA)
Title: Social network email filtering
Inventor: LITTLE CHARLES REEVES II
IPC: H04L12/58
Filed: 2005-03-24
Abstract: Social network email filtering is described. A user's address book includes a first group of email addresses. Those email addresses are used to identify address books that include another group of email addresses. Multiple iterations may be used to identify several groups of email addresses, representing a user's social network. When an email message addressed to the user is received, the message is trusted if the sending email address is within the user's social network.    Otherwise, the message is flagged as junk mail. Varying trust levels may be applied to messages that are received based on a distance within a social network between the sending email address and the user and/or how often the sending email address appears within the social network.
Patent CA-2503075-A1 (CA)
Inventor: PERETZ ASHER
IPC: A61K31/136
Filed: 2003-10-21
Abstract: L'invention concerne des composés, des compositions et des procédés qui sont utiles dans le traitement de maladies par la modulation du flux d'ions potassium dans les canaux potassiques dépendants d'une tension et/ou l'abaissement de l'activité des neurones corticaux. Particulièrement, l'invention présente des dérivés d'acide N-phénylanthranilique et de 2-benzimidazolone, des compositions et des méthodes utiles dans le traitement de troubles du système nerveux central périphérique et en tant qu'agents neuroprotecteurs.
Patent CA-2505699-A1 (CA)
Inventor: HAMMAH GILLIAN R
IPC: A47D13/08
Filed: 2005-04-26
Abstract: The Convert-a-Pillow is an adjustable 3-in-1 pillow for pregnant women, nursing mothers and infants. The invention comprises a rectangular middle pillow with two curved attachable/detachable extensions. When all sections are attached, this invention functions as a pregnancy pillow that supports either the back or abdomen of a pregnant woman when lying in a horizontal position. The pillow extensions can also be detached from the main rectangular section and attached to each other to form a C-shaped piece that functions as an infant support pillow. This function provides a baby or small child with additional back support until he/she can sit up independently. Each extension can also be used separately to function as a nursing pillow, to support an infant on her mother's (or other user's) lap while breast- or bottle-feeding, as well as to support the mother's arm. The Convert-a-Pillow can also be used for many other functions by attaching/detaching the extensions.
Patent CA-2507778-A1 (CA)
Title: Well bore cleaning and tubular circulating and flow-back apparatus
Inventor: MULLINS ALBERT AUGUSTUS
IPC: E21B21/10
Filed: 2003-10-28
Abstract: A method of cleaning casing (16) with a tubular wiper (22) and a valve arrangement (29).
Patent CA-2509725-A1 (CA)
Title: Rotational, translational and torqueing control members for an endoscopic instrument
Inventor: SMITH KEVIN W
IPC: A61B17/12
Filed: 2005-06-10
Abstract: A flexible endoscopic clip applier includes a flexible coil with a manual actuator coupled to one end and a jaw assembly coupled to the other end. A store of clips is arranged adjacent to the jaw assembly and a clip pusher is arranged adjacent to the store of clips. The actuator includes a lever for opening and closing the jaws, a knob for rotating the jaw assembly, and a crank for dispensing clips. The knob and the lever are coupled to a single control member which extends through the coil to a joiner where it is joined to a pair of pull wires coupled to the jaws. The crank is coupled to a second control member which is threaded along a distal portion. The threaded portion engages a threaded member near the pusher and is coupled to the pusher such that rotation of the threaded control member by the crank causes the pusher to be moved distally.
Patent CA-2511949-A1 (CA)
Title: Universal display media exposure measurement
Inventor: ZHANG JACK K
IPC: G06Q30/02
Filed: 2003-12-16
Abstract: Systems, methods and devices for gathering data concerning exposure of predetermined survey participants both to media data and to billboards are provided. A portable billboard and media data exposure monitor (200) arrange d to be carried on the person of a participant is provided. The monitor (200) includes billboard exposure means for producing billboard exposure monitorin g data (128); a media data exposure monitor; and an enclosure containing the billboard exposure means and the media data exposure monitor (200).
Patent CA-2518372-A1 (CA)
Inventor: ZHENG JIAN
IPC: G01N33/58
Filed: 2005-09-30
Abstract: The aim of the present invention is to provide a non-intrusive way to isolate, concentrate and monitor the TSE disease-related pathogenic prion protein.   The invention described several peptides and their ability to capture PrP Sc from brain homogenate of prion disease infected animal and human. These peptides do not capture cellular prion protein from individuals with no prion disease.
Patent CA-2518508-A1 (CA)
Inventor: MUMMERY CHRISTINE LINDSAY
IPC: C12N5/077
Filed: 2004-03-11
Abstract: A method for inducing cardiomyocyte differentiation of a hES cell, the method comprising co-culturing the hES cell with a cell excreting at least one cardiomyocyte differentiation inducing factor or with an extracellular medium therefrom, under conditions that induce differentiation, cells and cell populations so produced, and uses of the cells.
Patent CA-2519009-A1 (CA)
Title: Nucleotide sequences regulating gene expression and constructs and methods utilizing same
Inventor: KARCHI HAGAI
IPC: C12N15/63
Filed: 2004-03-11
Abstract: Novel plant derived regulatory sequences and constructs and methods of using such sequences for directing expression of exogenous polynucleotide sequences in plants are provided
Patent CA-2519142-A1 (CA)
Inventor: PROVENCHER PASCAL
IPC: E05D13/00
Filed: 2005-02-21
Abstract: A device (1) for use with a cable-operated door (3), such as garage doors (3) and the like, and a door assembly including the same. The device (1) is intended to reduce the risk of the door (3) falling, or at the very least slow down its descent, in the event of a failure in the counterbalancing mechanism of the door (3), which is generally represented by a loss of tension in a given tensioned cable (5) operating the door (3). The brake device (1) includes a support bracket (9), and a guiding assembly (15) and a braking assembly (17) mounted onto the support bracket (9). The braking assembly includes a swivel component (18) having opposite braking arm (19) and lever portion (20), the lever portion cooperating with the tensioned cable (3) so that in the event of a loss of tension in the cable (5), the braking arm (19) is urged onto an adjacent rail (7) via biasing means (21) for anchoring a knife (45) of the braking arm (19) into the rail (7) and stopping, or at the very least, slowing down the descent of the door (3), with respect to the rail (7).
Patent CA-2520165-A1 (CA)
Inventor: VOELKER MICHAEL
IPC: G01S13/90
Filed: 2005-09-20
Abstract: In a method for interferometric radar measurement, at least two synthetic aperture radar (SAR) systems on satellite and/or missile-supported platforms illuminate a common surface area by means of microwave signals. A first SAR system sends a first radar signal on a first transmit frequency, and at least a second SAR system sends at least a second radar signal on at least a second transmit frequency. At least one of the at least two SAR systems receives the at least two interfering radar signals reflected on the common surface area, determines difference phases of the received radar signals from the interferograms, determines therefrom a drift of a system clock of the at least two SAR systems, and compensates the determined drift.
Patent CA-2523678-A1 (CA)
Inventor: GREEN SOL
IPC: G06Q10/00
Filed: 2004-04-29
Abstract: A system and method for assessing the statistical and clinical acceptance of a new medical service or changes in products used by a clinical laboratory or hospital, and providing documentation of validation. The system and method includes an information exchange mechanism, such as an internet, extranet, compact disc (e.g., CD-ROM) or text-based mechanism to establish a systemati c approach between a provider and client for collecting (steps 5, 55), reviewi ng (steps 30, 80) and providing information (steps 10, 40, 60, 70, 90) to demonstrate the clinical validity of new or modified products. The collected information and user requests are evaluated using tools such as an analytica l array to determine required protocols, limits and subsequent tests needed to demonstrate the clinical validity of products, and thereafter, to provide a report to show validation of the change.
Patent CA-2523776-A1 (CA)
Inventor: DESJARLAIS JOHN R
IPC: C07K14/525
Filed: 2004-03-05
Abstract: The invention relates to BAFF protein mutants carrying at least one amino acid substitution at one position having dominant negative antagonist activity, receptor antagonist activity and agonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the BAFF protein mutants in the treatment of BAFF or APRIL-related disorders.
Patent CA-2524400-A1 (CA)
Inventor: MOY PAUL Y
IPC: C08L67/02
Filed: 2004-04-30
Abstract: Cette invention se rapporte à une composition de polymère de chlorure de vinyle qui contient un mélange d'une composition de bisphosphate à pont alkylène, comme agent ignifuge, et d'un plastifiant en polyester, constituant le produit de la réaction d'un diol aliphatique et d'un acide dicarboxylique.
Patent CA-2528460-A1 (CA)
Title: Magnetic nanoparticles
Inventor: MARTIN-LOMAS MANUEL
IPC: A61K9/50
Filed: 2004-06-07
Abstract: Materials and methods for making small magnetic particles, e.g. clusters of metal atoms, which can be employed as a substrate for immobilising a plurality of ligands. Also disclosed are uses of these magnetic nanoparticles as therapeutic and diagnostic reagents, and in the study of ligand-mediated interactions.
Patent CA-2529821-A1 (CA)
Title: Procede d'assemblage d'une structure de carrosserie de vehicule
Inventor: MILLS RICHARD DAVID
IPC: B21D53/88
Filed: 2003-12-22
Abstract: L'invention concerne un procédé destiné à la fabrication d'un ensemble carrosserie d'un véhicule à ordures et consistant à former un premier, un deuxième et un troisième composant de cet ensemble. Une première structure de positionnement et une seconde structure de positionnement sont formées de manière à comprendre une première structure d'accouplement conçue pour s'accoupler avec la première structure de positionnement, seul le deuxième composant étant ainsi positionné par rapport au premier composant. Le troisième composant est formé de manière à comprendre une seconde structure d'accouplement conçue pour s'accoupler avec la seconde structure de positionnement dans le premier composant, seul le troisième composant étant ainsi positionné par rapport au premier composant. Le deuxième composant est positionné par rapport au premier composant par accouplement de la première structure d'accouplement sur le deuxième composant avec la structure de positionnement dans le premier composant, et le troisième composant est positionné par rapport au premier composant par accouplement de la seconde structure d'accouplement sur le troisième composant avec la seconde structure de positionnement dans le premier composant. Le deuxième composant et le troisième composant sont soudés au premier composant.
Patent CA-2529834-A1 (CA)
Title: Tensioning board for slit metal rewinding
Inventor: SALVADOR GONZALO
IPC: F16B5/02
Filed: 2005-12-12
Abstract: An apparatus for tensioning strips of metal as the metal strips are rewound comprises a board having a top surface defining a groove and a tray having opposed side portions and opposed end portions and disposed in the groove. Each of the side portions of the tray has an upturned flange. A hook pad having a plurality of upwardly extending hooks is disposed in the tray between the flanges. The hook pad and tray are removably fastened to the board.
Patent CA-2530981-A1 (CA)
Title: Intake air amount control system for internal combustion engine
Inventor: YASUI YUJI
IPC: F02D41/14
Filed: 2004-05-28
Abstract: An intake air volume controller of an internal combustion engine in which variation in the intake air volume can be corrected appropriately among cylinders and both operability and exhaust gas characteristics can be enhanced even in a normal operating load area including a high load area. The ECU (2) in the intake air volume controller (1) of an internal combustion engine (3) controlling the intake air volume of four cylinders #1-#4 independently through a variable phase mechanism (80) between intake cams identifies an intake air volume variation coefficient (.PHI.#i) such that an estimated value (Gth_est) matches a TH passing intake air volume (Gth) based on a model [formula (43)] defining the relation of the estimated value (Gth_est) of TH  passing intake air volume and a plurality of simulation values (Gcyl_0S#i), calculates, for each cylinder, a target phase between intake cams (.theta.ssi#i_cmd) depending on the identified intake air volume variation coefficient (.PHI.#i) (step 81), and calculates control inputs (DUTY_ssi#2-#4) to the variable phase mechanism (80) between intake cams depending on the target phase between intake cams (.theta.ssi#i_cmd) (step 75).
Patent CA-2531853-A1 (CA)
Title: Pharmaceutical formulation comprising levothyroxine sodium
Inventor: KROHN HEINER
IPC: A61K31/198
Filed: 2004-07-08
Abstract: There is provided a stable pharmaceutical formulation comprising (a) an effective amount of levothyroxine sodium, (b) microcrystalline cellulose whi ch has a mean particle size of less than 125~m and is present in an amount of 6 0 to 85% w/w based upon the total weight of the formulation, and (c) pregelatinised starch present in an amount of 5 to 30% w/w based upon total weight of the formulation. There is also provided a process for the preparation of such a formulation.