baber/WOPTO huggingface dataset:
Patent DE-69405232-D1 (DE)
Inventor: GLENSBJERG MARTIN
IPC: C12R1/42
Filed: 1994-05-31
Granted: 1997-10-02
Abstract: The invention provides methods for the rapid determination/detection of Salmonella in samples from sources such as processed and raw foods and feeds, the environment, body fluids and biopsies, etc. The methods comprise an enrichment step and a determination step. The enrichment procedure involves selective conditions, notably the use of the selective substances tetrathionate and/or novobiocin or an increase in culturing temperature to 39-43  DEG C, favouring the early detection of Salmonella. The selective conditions are instituted as early as possible in the enrichment, thereby allowing an early determination of high specificity and sensitivity. The determination involves a variety of assays which are all different from traditional agar plating techniques. Also provided are special enrichment procedures for Salmonella in processed products, i.e. products which have been heat-treated, dried, cured, acidified etc.. In general, determination/detection of Salmonella can be performed within 24 hours from the institution of enrichment.
Patent DE-69408807-D1 (DE)
Inventor: BLEAKLEY IAN STUART
IPC: D21H17/69
Filed: 1994-06-20
Granted: 1998-04-09
Abstract: There is disclosed a process for separating fine solids from water in the used water recovery system of a sheet forming mill, wherein the used water recovery system includes at least one stage in which an alkaline earth metal carbonate is precipitated in the aqueous suspension constituting the used water whereby the particulate material present in the used water becomes entrained in the alkaline earth metal carbonate precipitate. By the invention it is possible to recover the water and the fine solid materials which pass through the wire mesh belt of a paper or board forming machine, and optionally recycle those recovered materials.
Patent DE-69412888-D1 (DE)
Inventor: JONSSON SONNY
IPC: C08F2/46
Filed: 1994-03-03
Granted: 1998-10-08
Abstract: Composition containing charge transfer complex from at least one unsaturated compound having an electron donor group and having an electron withdrawing group and being free of any photoinitiating compound is polymerized by being subjected to ultraviolet light.
Patent DE-69413800-D1 (DE)
Inventor: KOZAK WILLIAM
IPC: B01D15/04
Filed: 1994-01-13
Granted: 1998-11-12
Abstract: A system automated for providing at least periodic removal of metal ions and contaminants from a chemical bath, consists of a microprocessor programmed for controlling fluid circuits of pumps and valves, for in one state of operation circulating a first predetermined quantity of the chemical bath from a first tank, through an ion exchange column, and back to the first tank; for in a second state of operation circulating deionized water from a second tank into the IEX column for displacing residual chemical bath therefrom for return to the first tank; for in a third state of operation circulating deionized water through the IEX column, and discharging the rinse water from a waste port; for in a fourth state of operation circulating regenerant acid through the ion exchange column, and discharging the used acid from a waste port; for in a fifth state of operation circulating deionized water through the IEX column for rinsing acid regenerant therefrom and discharging the same out of a waste port; and for in a sixth state of operation circulating chemical bath into the IEX column for displacing residual rinse water therefrom, and discharging the same out of the waste port, in preparation for a cycle of treatment of the chemical bath.
Patent DE-69417524-D1 (DE)
Inventor: SRINIVASAN PADMANABHAN
IPC: C10M107/38
Filed: 1994-11-28
Granted: 1999-05-06
Abstract: Greases comprising a mineral and/or synthetic lubricating oil having an hydrogenated basis, a fluoropolyethereal oil and an organic or inorganic thickening agent, wherein the weight ratio lubricating oil + fluoropolyethereal oil / thickening agent ranges from 97:3 to 80:20 and the weight ratio lubricating oil / fluoropolyethereal oil ranges from 95:5 to 60:40.
Patent DE-69421708-D1 (DE)
Inventor: TICHELAAR JOHANNES
IPC: H04N5/44
Filed: 1994-05-26
Granted: 1999-12-23
Abstract: In an extended television signal comprising signalling bits for conveying control information to control an extended decoder, the signalling bits comprise a start code and data bits, the start code's main lobe of spectral energy resides in the lower spectral area of a baseband television signal below 2 MHz and preferably below 1.7 MHz, the start code is preferably (almost) DC-free, and the start code has good aperiodic correlation properties and a predetermined minimum bit Hamming distance to the data bits when shifted in the direction of the data bits following the start code.
Patent DE-69424052-D1 (DE)
Inventor: YOON JUNE
IPC: A61K31/4709
Filed: 1994-01-21
Granted: 2000-05-25
Abstract: FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to new derivatives of quinolone carboxylic acid of the formula (I) $$$, their pharmaceutically acceptable salts and hydrates where X means hydrocarbon group, fluorocarbon group or nitrogen atom; Y means hydrogen atom or methyl group; $$$ means hydrogen atom or $$$-alkyl group; $$$ means a group of the formula (a) $$$ where A and B mean fluorocarbon group or nitrogen atom at condition that when A is CF then B is N and when A is N then B is CF; $$$ means a group of the formula (b) $$$ where substitute $$$ means amino-group with racemate or (S)-enantiomer formation, or a group of the formula (c) $$$ where substituents $$$ and $$$ mean hydrogen atom or $$$-alkyl group. Derivative of quinolone carboxylic acid of the formula (I) is synthesized by condensation of compound of the formula (II) $$$ and compound of the formula $$$ in solvent in the presence of acid acceptor and excess of compound of the formula $$$ that is one of reagents. Solvent is taken from a group involving pyridine, acetonitrile, N,N-dimethylformamide. In compound of the formula (II) and compound of the formula $$$ substituents X, Y, Z, $$$ and $$$ mean values indicated above. EFFECT: improved method of synthesis. 11 cl, 6 tbl, 29 ex
Patent DE-69432636-D1 (DE)
Inventor: MATTEUCCI D
IPC: C12Q1/6816
Filed: 1994-09-16
Granted: 2003-06-12
Abstract: Compounds having particular interest as labels and various novel uses in diagnostics and therapeutics are provided which have structure (1) wherein R<SUP>1 </SUP>is a binding partner, a linker or H; a and b are 0 or 1, provided that the total of a and b is 0 or 1; A is N or C; X is S, O, -C(O)-, NH or NCH<SUB>2</SUB>R<SUP>6</SUP>; Y is -C(O)-; Z is taken together with A to form an aryl or heteroaryl ring structure comprising 5 or 6 ring atoms wherein the heteroaryl ring comprises a single O ring heteroatom, a single N ring heteroatom, a single S ring heteroatom, a single O and a single N ring heteroatom separated by a carbon atom, a single S and a single N ring heteroatom separated by a carbon atom, 2 N ring heteroatoms separated by a carbon atom, or 3 N ring heteroatoms at least two of which are separated by a carbon atom, and wherein the aryl or heteroaryl ring carbon atoms are unsubstituted with other than H or at least 1 nonbridging ring carbon atom is substituted with R<SUP>6 </SUP>or -O; R<SUP>6 </SUP>is independently H, C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl, C<SUB>2</SUB>-C<SUB>6 </SUB>alkenyl, C<SUB>2</SUB>-C<SUB>6 </SUB>alkynyl, NO<SUB>2</SUB>, N(R<SUP>3</SUP>)<SUB>2</SUB>, C≡N or halo, or an R<SUP>6 </SUP>is taken together with an adjacent R<SUP>6 </SUP>to complete a ring containing 5 or 6 ring atoms; R<SUP>3 </SUP>is a protecting group or H; and tautomers, solvates and salts thereof; and provided that where a is 0, b is 1, and R<SUP>1 </SUP>is in which D<SUP>2 </SUP>is independently hydroxyl, blocked hydroxyl, mono, di or triphosphate, or an oligodeoxyribonucleotide otherwise containing only the bases A, G, T and C; and D<SUP>3 </SUP>is H or OH; then Z is not unsubstituted phenyl. Also provided are novel intermediates and methods for the preparation and use of the structure (1) compounds.
Patent DE-69434420-D1 (DE)
Inventor: SEDDON ANDREW PETER
IPC: A61P5/00
Filed: 1994-09-23
Granted: 2005-08-11
Abstract: Structural analogues of fibroblast growth factors have an amino acid sequence replacement in the ninth or tenth beta strand of the factor, or the sequence that corresponds to the surface loop that connects the ninth and tenth beta strands, such that the folding of the molecule is not significantly perturbed. Preferred analogues have the overall secondary and tertiary structure of the original factor, and bind to heparin and a member or members of the fibroblast growth factor receptor family with high affinity. In some embodiments the replacement is with another amino acid sequence such as a loop sequence from another structurally related fibroblast growth factor or an interleukin. The figure discloses amino acid sequences from FGF-1, FGF-2, and IL-1 beta.
Patent DE-69434552-D1 (DE)
Inventor: RING D
IPC: B65D23/10
Filed: 1994-04-11
Granted: 2005-12-29
Abstract: A blow moulded plastic container (10) having a small diameter vent tube (30) integrally moulded on the top wall and forming an air vent passageway between the pour spout opening (28) and the chamber (22) in the bottle. A substantially larger hollow handle (46), closed at both ends, is integrally moulded on top of the vent tube in spaced relationship above the top wall (24) to form a hand opening. <IMAGE>
Patent DE-69435038-D1 (DE)
Inventor: WOZNEY JOHN M
IPC: A61K38/18
Filed: 1994-09-07
Granted: 2007-12-06
Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
Patent DE-69500862-D1 (DE)
Inventor: MARKYVECH RONALD KEITH
IPC: B60W10/04
Filed: 1995-03-27
Granted: 1997-11-20
Abstract: An adaptive control system/method for an at least partially automated mechanical transmission system (10) is provided for determining if selected upshifts into a target gear ratio are feasible (208) or not feasible (210) under current vehicle operating conditions and for prohibiting the initiation of not feasible selected upshifts. If upshifts determined to be feasible are not completed by the system, the logic rules by which upshift feasibility is determined are modified to render such rules less aggressive. <IMAGE>
Patent DE-69507482-D1 (DE)
Inventor: SIEBER WERNER
IPC: C12Q1/6834
Filed: 1995-06-22
Granted: 1999-03-04
Abstract: PCT No. PCT/EP95/02441 Sec. 371 Date Jan. 3, 1997 Sec. 102(e) Date Jan. 3, 1997 PCT Filed Jun. 22, 1995 PCT Pub. No. WO96/02060 PCT Pub. Date Jan. 25, 1996This invention relates to magnetic particles comprising mixed oxides of divalent metals and iron (III), having a diameter of 1-10 nm and a surface area of 120-350 m2/g, with silanes bound to the surface of said particle. It also relates to (1) the process for making said particles by simultaneous precipitation and silanization from aqueous solution and (2) their use as carrier materials for the magnetic separation of substances immobilized therewith.
Patent DE-69514519-D1 (DE)
Inventor: MCMURTREY D
IPC: G11B25/04
Filed: 1995-06-02
Granted: 2000-02-17
Abstract: High density disc drive apparatus that packs a large number of disc drives into a computer cabinet. The disc drives are removably installed in disc cages mounted on shelves of a drawer that slides out the front of the cabinet. A linear actuator drives the drawer and a controller moderates the actuator to ensure smooth start-up and stopping of the drawer so selected disc drives can be replaced during computer operation without disturbing the operation of the remaining disc drives. Built-in pin connectors facilitate bringing I/O and power cables to the disc drives and the desired replacement.
Patent DE-69527839-D1 (DE)
Title: Tropan-2-aldoximderivate als neurotransmitter "reuptake" inhibitoren
Inventor: MOLDT PETER
IPC: C07D451/02
Filed: 1995-04-12
Granted: 2002-09-26
Abstract: PCT No. PCT/EP95/01358 Sec. 371 Date Oct. 11, 1996 Sec. 102(e) Date Oct. 11, 1996 PCT Filed Apr. 12, 1995 PCT Pub. No. WO95/28401 PCT Pub. Date Oct. 26, 1995The present invention discloses compounds of the formula,   <IMAGE>    <IMAGE>   any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein R, R3, and R4 each have the meanings set forth in the specification. The compounds possess valuable pharmaceutical properties as monoamine neurotransmitter, i.e dopamine, serotonin, noradrenalin, reuptake inhibitors.
Patent DE-69529649-D1 (DE)
Inventor: KETTLEBOROUGH A CATHRINE
IPC: C12N15/13
Filed: 1995-03-16
Granted: 2003-03-27
Abstract: PCT No. PCT/EP95/00978 Sec. 371 Date Nov. 17, 1995 Sec. 102(e) Date Nov. 17, 1995 PCT Filed Mar. 16, 1995 PCT Pub. No. WO95/25167 PCT Pub. Date Sep. 21, 1995This invention relates to new anti-EGFR antibodies and single-chain Fvs (scFvs) thereof which can be obtained from phage-antibody libraries constructed from cells of an immunized mammalian, preferably a mouse. Two of the single-chain Fvs isolated from the phage-antibody libraries were engineered to create partially humanized whole antibody molecules. These chimeric anti-EGFR antibodies contain constant regions of human immunoglobulins, and can be used as well as the single-chain Fvs as agents for the diagnosis and therapy of human tumors.
Patent DE-69529758-D1 (DE)
Inventor: KESHI HIROYUKI
IPC: C12Q1/68
Filed: 1995-10-02
Granted: 2003-04-03
Abstract: A probe derived from phlogogenic bacteria of pneumonia, containing fragments of DNA which streptococcus pneumoniae essentially possesses, and useful for detecting and identifying causative bacteria of pneumonia is obtained by completely digesting the DNA with a restriction endonuclease PstI, followed by cloning into a suitable vector. <IMAGE>
Patent DE-69534456-D1 (DE)
Inventor: WEISMAN S MILLER II
IPC: F02D41/04
Filed: 1995-05-15
Granted: 2005-10-20
Abstract: A method for comprehensive integrated control of an internal combustion engine, such as a compression-ignition engine, utilizing an electronic control module (20) is disclosed. The control strategy integrates various functions of engine control including an acceleration balance test for the engine cylinders, a fuel economy vehicle speed limit adder, a fuelling limit for high altitude vehicle operation, throttle logic, a data-hub for operation trending and vehicle component lifting analyses, a gear ratio torque limit, an air temperature based torque limit, enhanced cooling fan control, and a idle shutdown strategy based on ambient air temperature.
Patent DE-69535298-D1 (DE)
Inventor: JACOB STANLEY W
IPC: A61K31/10
Filed: 1995-12-29
Granted: 2006-12-28
Abstract: A method of pharmaceutically managing snoring is provided by the instillation intranasally of a solution containing 1-20% methylsulfonylmethane by weight dissolved in water so as to saturate the nasal mucous membranes. Preferably, the solution has between 10%-16% by weight methysulfonylmethane. The solution may be buffered, and/or a mild analgesic may be included. The method prefers that instillation occur as close to the sleep event as possible, and it should be at least within one hour before a person retires for sleep. The solution may be introduced by spray or drop-wise, and a product packaging the solution in a suitable container is described.
Patent DE-69610625-D1 (DE)
Inventor: SIDDLE R
IPC: B23C5/22
Filed: 1996-03-06
Granted: 2000-11-16
Abstract: A cartridge-type milling cutter is provided having a cartridge mounting mechanism that resists the centrifugal load applied to the cartridges at high rotational speeds. The milling cutter includes a generally cylindrical cutter body, at least one replaceable tool cartridge having a trailing face, and a leading face having a cutting insert for cutting a workpiece, and a mounting mechanism for detachably securing the tool cartridge onto the cutter body. The mounting mechanism includes a recess in the cutter body for receiving the cartridge that includes a radially canted wall for providing dovetail-type resistance to radial movement of the cartridge, and at least one compressively loaded set screw in the cutter body for compressively engaging the leading face of the cartridge in order to seat and retain it within the recess. During the operation of the cutter, the centrifugal load is substantially borne by the combination of the radially canted wall and the set screw. The mounting mechanism preferably also includes a screw, optionally radially-oriented, that passes through a through bore in the sides of the tool cartridge for providing additional insurance against the loosening or breaking away of the cartridge during high speed operation.
Patent DE-69614278-D1 (DE)
Inventor: MEYER ERIC R
IPC: A61G7/057
Filed: 1996-01-03
Granted: 2001-09-13
Abstract: A sleep support surface includes a mattress having at least two bladders located adjacent a foot end. The bladders each have a predetermined, adjustable internal pressure. The pressure in at least one of the bladders is selectively and independently reduced to provide pressure relief on the heels of the patient lying on the mattress. The pressure in a bladder located toward the head end of the mattress and adjacent the at least one bladder is increased. This pressure increase advantageously provides the lifting force under the calves of the patient to reduce further pressure on the patient's heels. A visual indication of the location each of the at least two bladders in the mattress is provided to facilitate selection of the at least one bladder in which to reduce pressure during the pressure reducing step, thereby providing pressure relief on the heels of the patient lying on the mattress. The at least one bladder in which to reduce the pressure is selected based on a position of the patient's heels on the mattress relative to the visual indication of the location of each of the bladders. <IMAGE>
Patent DE-69616029-D1 (DE)
Inventor: HUDLICKY TOMAS
IPC: C07D491/04
Filed: 1996-02-14
Granted: 2001-11-22
Abstract: This is described an improved process for the asymetric synthesis of (+)-Pancratistatin utilizing aziridines as the starting materials.
Patent DE-69635809-D1 (DE)
Title: Atopy, diagnose und therapie
Inventor: COOKSON OSMOND
IPC: C12Q1/6883
Filed: 1996-08-29
Granted: 2006-04-20
Abstract: PCT No. PCT/GB96/02095 Sec. 371 Date Feb. 25, 1998 Sec. 102(e) Date Feb. 25, 1998 PCT Filed Aug. 29, 1996 PCT Pub. No. WO97/08338 PCT Pub. Date Mar. 6, 1997The invention relates to a method for diagnosing an individual as having atopy or a predisposition thereto. The method involves demonstrating in the individual the presence or absence of either: (i) an unusual variant form of the gene which codes for the beta sub-unit of the high affinity receptor for IgE (Fc epsilon RI beta ), the variant form comprising a variation in exon (7) which encodes a glycine at amino acid residue 237 instead of glutamic acid which appears at residue 237 in individuals without atopy: or (ii) an unusual polymorphic form of the amino acid sequence for Fc epsilon RI beta , the polymorphic form comprising glycine at amino acid residue 237 instead of glutamic acid which appears at residue 237 in individuals without atopy. Materials and other methods relating to the above diagnostic method are also described.
Patent DE-69638316-D1 (DE)
Inventor: MALINER BRUCE J
IPC: B31D1/02
Filed: 1996-07-08
Granted: 2011-02-17
Abstract: A roll fed labelling system and associated label are disclosed. The label (12) includes a triggering mark (28) formed of luminophor ink, i.e. containing a fluorescent optical brightening agent, that reflects as visible light directed UV light. A modulated UV light is directed at the label and the modulated reflected visible light is detected and used to trigger a cutting mechanism to separate a single label from the remainder of the roll. The triggering mark need not visibly contrast with the surrounding graphics of the label and may be invisible in visible light. When producing the roll of labels, the amount of brightening agent may be controlled by monitoring the luminescence of the triggering mark relative to a reference level which may be derived with reference to a miximum luminescence of other parts of the label.
Patent DE-69700277-D1 (DE)
Inventor: LION BERTRAND
IPC: A61K8/92
Filed: 1997-06-06
Granted: 1999-07-22
Abstract: The use of at least one oligomer (I) is claimed as plasticiser for a film-forming polymer (II), in and for the preparation of a cosmetic or dermatological composition (A) containing (II), provided that (A) does not contain a film-forming polymer of the nitrocellulose type. (I) are selected from homo- or copolymers of ethylenically unsaturated monomers and polycondensates, and have an average molecular weight (measured at the peak apex by steric exclusion chromatography) of 400-10,000 (preferably 500-5,000) and a glass transition temperature of -80 to +10 (preferably -70 to +5) degrees C. Also claimed is the composition (A) containing (I) and (II), each dissolved or dispersed in a cosmetic or dermatological carrier.
Patent DE-69700903-D1 (DE)
Inventor: CARDOSO JAOQUIM P
IPC: C07D503/00
Filed: 1997-03-24
Granted: 2000-01-13
Abstract: The invention relates to the process for the isolation of a pharmaceutically acceptable alkali metal salt of clavulanic acid from a fermentation broth containing impure clavulanic acid comprising the steps of filtration of the fermented broth, extraction of the clavulanic acid to a water immiscible or partly water immiscible solvent at pH from 1.2 - 2, precipitation of an alkali metal salt A of clavulanic acid by addition of a solution of an alkali metal alkylalkanoate, characterized by the following steps:   before the filtration the fermented broth containing clavulanic acid is diluted with water, a flocculating agent is added and the pH is adjusted to 3 - 5 for further purification the alkali metal salt A of clavulanic acid is converted to clavulanic acid by addition of an inorganic acid and is extracted into a water immiscible or partly water immiscible solvent a solution of a different alkali metal B alkyl alkanoate is added and the alkali metal salt B of clavulanic acid is precipitated.
Patent DE-69702084-D1 (DE)
Inventor: TAYLOR CHARLES S
IPC: A61B17/02
Filed: 1997-02-20
Granted: 2000-06-29
Abstract: An access platform (10) having a first and a second blade (50,51) interconnected to a spreader member (12) that laterally drives the blades apart or together and a sternal pad (80,81) interconnected to a blade. The superior blade is pivotally coupled to the spreader member such that it naturally rises as the blades are separated. Alternatively, a vertical displacement member is operably interconnected to a blade and the spreader member and is used to vertically displace the interconnected superior blade and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor (70,71) is interconnected to the blades to draw the soft tissue around an incision away from the surgeon's working area.
Patent DE-69704426-D1 (DE)
Inventor: TESTA EMILIO
IPC: A61K47/48
Filed: 1997-04-28
Granted: 2001-05-03
Abstract: The present invention relates to a medicated chewing gum comprising a pharmaceutically active agent incorporated therein. The medicated gum is used as a means for administering the active agent to a subject. The invention also relates to a method of preparing the medicated chewing gum. The process involves the formation of a cyclodextrin-active agent inclusion complex, which is dried and mixed with a granulated gum base without adding water or other solvents. The process is carried out under controlled temperature and humidity and the blended components are cold-pressed to produce a final gum product.