baber/WOPTO huggingface dataset:
Patent NZ-232489-A (NZ)
Title: Cross-linked antibody conjugate comprising labelled antibody and non-disulphide bridge
Inventor: RHIND STEPHEN KEITH
IPC: A61K47/48
Filed: 1990-02-12
Abstract: Cross-linked labelled antibody conjugates are described which have at least one non-disulphide interchain bridge. The bridge may be the residue of a homo- or hereofunctional cross-linking reagent, and is located away from the antigen binding domains of the antibody. The antibody conjugates have an enhanced binding capacity and in vivo have good blood clearance and, in the presence of a tumour high tumour: blood and tumour: bone ratios. The conjugates are of use in the diagnosis and therapy of e.g. tumours and may be prepared by reaction of a cross-linking reagent with an antibody.
Patent NZ-234356-A (NZ)
Title: Vacuum switch screen; process for installing it in switch body
Inventor: SCHELLEKENS HANS
IPC: H01H33/662
Filed: 1990-07-04
Abstract: In the process of fixing a metal screen in the housing of a vacuum switch, the screen is plastically deformed radially outwards over an internal supporting edge in the housing. The plastic deformation of the screen is carried out at an edge thereof, in such a way that an outward flanged edge is formed. Thus, the screen is retained on the supporting edge by that flanged edge and a part of the housing with a relatively large diameter. Therefore, the screen has a part with a relatively small diameter which is essentially equal to the internal diameter of the supporting edge of the housing.
Patent NZ-237363-A (NZ)
Title: Imidazo(1,2-c)quinazoline derivatives, preparation and pharmaceutical compositions thereof
Inventor: BOURGUIGNON JEAN-JACQUES
IPC: A61P9/08
Filed: 1991-03-08
Abstract: New imidazo [1,2-c] quinazoline compounds useful as coronary smooth muscle relaxants and corresponding to the formula:  <IMAGE>  in which: Y is oxygen or sulfur; R1 is (C1-C6) alkyl optionally substituted by a phenyl itself optionally substituted, a (C3-C6) cycloalkyl, optionally substituted phenyl, furyl, thienyl or acyl; R2 is hydrogen, a halogen or a (C1-C6) alkyl optionally substituted by amino or dialkylamino; R3 is hydrogen, (C1-C6) alkyl optionally substituted by an aryl, or R-CO-(CH2)n- [n being 1, 2 or 3, and R being (C1-C6) alkoxy, amino, (alkyl or dialkyl)amino, morpholino or methylpiperazinyl]; and X is hydrogen or a halogen. These compounds and their physiologically tolerated salts can be used in medical treatment of coronary smooth-muscle dysfunctions.
Patent NZ-238990-A (NZ)
Title: 4-substituted phenyl-3-(hetero)cyclyl alkyl (amino, oxy or thio)methyl piperidine derivatives and pharmaceutical compositions
Inventor: JAKOBSEN PALLE
IPC: A61P25/08
Filed: 1991-07-16
Abstract: The present invention relates to piperidine derivatives of the formula:   <IMAGE>   wherein, R, R1, R3, X, and n are defined in the specification, pharmaceutical compositions thereof and methods of treating anoxia, traumatic injury, ischemia, migraine and epilepsy.
Patent NZ-240833-A (NZ)
Title: Powder inhalation device with metering chamber
Inventor: BACON RAYMOND
IPC: A61M15/00
Filed: 1991-12-02
Abstract: PCT No. PCT/GB91/02117 Sec. 371 Date Apr. 22, 1993 Sec. 102(e) Date Apr. 22, 1993 PCT Filed Nov. 29, 1991 PCT Pub. No. WO92/10229 PCT Pub. Date Jun. 25, 1992.A powder inhalation device includes a powder reservoir which contains a powdered medicament and a volume of air. The volume of air is disposed between an upper surface of the powdered medicament and a cover member of the powder reservoir. A metering chamber extends from the powder reservoir, and an apparatus is included for compressing the volume of air within the reservoir. A passage extending from the reservoir to the atmosphere is provided to allow air to vent from the powder reservoir, through the metering chamber, and into the atmosphere as the pressure of the volume of air in the powder reservoir is increased by the compressing apparatus. The volume of air thereby causes the powdered medicament to be forced into the metering chamber, and through a selectively openable barrier into an inhaling chamber.
Patent NZ-242997-A (NZ)
Title: Portable, inflatable, ribbed leg supporting bolster
Inventor: BENNETT TREVOR STEARN
IPC: A61G7/05
Filed: 1992-06-03
Abstract: An inflatabled leg-supporting bolster includes a pair of flexible side panels joined to opposite side edges of a connecting flexible sheet that encircle them. A horizontal web and a plurality of upright webs are provided at the interior of the bolster to define lateral and upright configurations required for proper leg support when used by a person lying in a supine position.
Patent NZ-318833-A (NZ)
Title: A hand holdable manually dispensing mastic container formed by facing sheets each being of two trapezoidal portions joined along a common long base
Inventor: DAVID COLIN MICHAEL
IPC: B65D75/58
Filed: 1996-09-26
Abstract: A "hand holdable" manually dispensing mastic container and a method of dispensing mastic is disclosed. A "hand holdable" manually dispensing mastic container (1) is made from two sheets of transparent plastics material which are welded together at a seam (7) around the periphery thereof. The container is formed to have a dispensing edge (4) and a filling end (3) which are parallel to one another. The container has a generally elongate shape which diverges from the dispensing edge to a widest dimension, indicated by numeral (6) and parallel to the dispensing edge, and then converges to the filling end. Thus, two trapezoidal portions are formed generally identified by numerals (11 and 12) respectively. The volume of portion (11) closest to the dispensing edge is smaller than the volume of portion (12) closest to the filling end.  The mastic is dispensed by cutting across the top (guide notches 5 typically being provided).  In an alternative embodiment (not shown) a screwed cap is provided.
Patent NZ-325747-A (NZ)
Title: Stomach-action molluscicides
Inventor: YOUNG COLIN LESLIE
IPC: A01N25/00
Filed: 1997-01-22
Abstract: A method of preparation of a stomach-action molluscicide comprising a metal complexone as an active ingredient and a carrier therefor, comprising the steps of:  (i) blending the components together to form a blended composition; (ii) heating the blended composition for about 1 to 5 minutes in the presence of steam at an ambient temperature of between about 80 DEG C and 100 DEG C; (iii) maintaining the composition at the ambient temperature between about 10 and 30 seconds; and (iv) forming the blended composition into one or more pellets.  <??>Preferably, the metal complexone is ÄFe(OH)EDTAÜ<2->.
Patent NZ-335913-A (NZ)
Title: Milking apparatus including a frame having a "C" front view configuration
Inventor: VAN DEN BERG KAREL
IPC: A01K1/12
Filed: 1997-07-01
Abstract: Apparatus for milking animals, comprising an implement and a unit to carry teat cups 25, is claimed.  The implement comprises a frame construction 2 sustaining the implement mainly from one side and the frame construction has the configuration of a "C" from the front view.
Patent NZ-337613-A (NZ)
Title: Packaging device for objects or stacks of objects with lower mechanism having four corner modules with folding plates being adjustable in plan area and being rotatable about a vertical axis
Inventor: SALM THOMAS
IPC: B65B25/14
Filed: 1999-09-02
Abstract: An equipment for wrapping stacks of items, eg. printed matter, envelopes etc. has each stack (3) placed onto a flat form blank (20) on a work surface (51). Four folding modules under the work surface are fitted with hinge plates which swing up and fold the sides and ends of the pack onto the stack and fold the tags into position. The tags are coated by adjustable adhesive sprays. The spacing of the four modules is adjustable to the required size of the pack and the modules are on a mounting which can pivot about a central vertical axis to align with the packs. An upper folding mechanism (10) prepares the lid to complete the pack.
Patent NZ-501917-A (NZ)
Title: Method and apparatus for enzymatic reactions performed on nucleic acid arrays conducted at dew point
Inventor: TABONE JOHN C
IPC: C12Q1/6858
Filed: 1998-07-21
Abstract: The method for amplifying nucleic acid molecules from a template, comprises: (a) mixing single-stranded nucleic acid templates on a solid substrate such as a silicon wafer or glass slide, with a solution comprising an oligonucleotide primer that hybridizes to the templates and a DNA polymerase, wherein the mixing occurs in discrete areas on the substrate, and the solution remains in the discrete areas; (b) synthesizing a complementary strand to the template to form a duplex; (c) denaturing the duplex; and (d) synthesizing complementary strands to the template, thereby amplifying nucleic acid molecules; wherein mixing, synthesizing, and denaturing are conducted at dew point. The dew point may be maintained using an apparatus, comprising a container capable of being pressurized; a heating device; a means for generating pressure; and a means for generating saturated steam.  The heating device, pressure generating means and steam generating means are controllable.  The method may be adapted for detecting a single base alteration in a nucleic acid molecule, by incorporating a DNA ligase in the solution, and including a step to detect a ligation product. The first and second oligonucleotides will not ligate when there is a single base alteration at the junction base on the nucleic acid molecule. The method may also be adapted for performing single nucleotide extension assays by including a extension product detection step.
Patent NZ-505751-A (NZ)
Title: Synthesis of tetrahydroxydiboron esters with acid sensitive alcohols in the presence of a Group VIII metal catalyst
Inventor: MARCUCCIO SEBASTIAN MARIO
IPC: C07F5/02
Filed: 1998-12-23
Abstract: A boron derivative of Formula (I) useful in the preparation of organic boronic acid derivatives. The diboron derivatives are also useful for preparing organic boronic acid derivatives for organic coupling reactions. The organic boronic acid derivatives are prepared by the reaction of a diboron derivative of Formula (I) and an organic compound in the presence of a Group VIII metal catalyst. Wherein, R1, R2, R3 and R4 are each independently selected from the group consisting of optionally substituted alkenyl, aryl, cycloalkyl, cycloalkenyl, a group of formula -R5Q)mR6 where Q is selected from O, S, NR7, arylene, cycloalkylene, m is an integer from 1-3, or each R5 is independently C1-3alkylene, R6 is C1-3alkyl or hydrogen and R7 is hydrogen or C1-12alkyl; and each X is independently selected from O, S(O)n and NR7, where n is an integer of 0-3 and R7 is hydrogen or C1-12alkyl, or one or more of -NR1R7, NR2R7, NR3R7 and NR4R7 represents an optionally substituted 5 or 6 membered heterocyclyl group, other than unsubstituted piperidyl and unsubstituted pyrolidinyl.
Patent NZ-505905-A (NZ)
Title: Metallocorrinoids as biologically compatible carriers of nitric oxide (NO)
Inventor: BAUER JOSEPH A
IPC: A61K31/714
Filed: 1998-12-30
Abstract: A method for making a complex of a metallocorrinoid and pharmacological agent (especially nitric oxide) comprising the steps of: i) Providing a metallocorrinoid with the structure of formula (I), where M is a metal ion selected from Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu and Zn; R1-R23 are moieties independently selected from H, aliphatic groups having from 1 to 30 carbon atoms, aromatic groups having from 1 to 30 carbon atoms, heteroatoms, and combinations thereof, where at least one of R1 and R2 is also a good leaving group. ii) Dissolving the metallocorrinoid in a non-donating solvent and exposing the dissolved metallocorrinoid to a pharmacological agent selected from the group consisting of free radicals and nucleophiles such that at least one of R1 and R2 is removed and the pharmacological agent becomes bound to M in place of the removed R1 or R2 group, where the pharmacological agent is not released from the metallocorrinoid under physiological conditions, and where the pharmacological agent is released from the metallocorrinoid under acid conditions. Also described is a compound comprising a complex having the general formula (III), where M is a metal ion selected from Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu and Zn; P is a pharmacological agent selected from free radicals and nucleophiles bound to M under physiological conditions; R2 is a compound having an electron-donating group; R3-R23 are moieties independently selected from H, aliphatic groups having from 1 to 30 carbon atoms, aromatic groups having from 1 to 30 carbon atoms, heteroatoms, and combinations thereof, and nitric oxide.
Patent NZ-506644-A (NZ)
Title: Emulsion preconcentrates containing cyclosporin or a macrolide
Inventor: AMBUHL MICHAEL
IPC: A61K47/34
Filed: 1999-03-04
Abstract: A composition in form of an emulsion or microemulsion pre-concentrate for oral administration comprises a cyclosporine or macrolide, and a carrier medium. The carrier medium comprises: a) a second component comprising triethyl citrate; a lipophilic component, and 4) a surfactant, with the proviso that: i) the composition is free or substantially free of ethanol, and ii) the composition is not in the form of a microemulsion pre-concentrate wherein the lipophilic component consists of one or a mixture of oils selected from triglycerides of medium chain fatty acid, mono- and di-glyceride and mono and di-acetylated monoglyceride or b) a second component comprising fatty acids and alcohols, N- methyl pyrrolidone or glycerol triacetate; a lipophilic component, and a surfactant, with the proviso that: i) the second component consists of glycerol triacetate, the composition further comprises ethanol; ii) the second component consists of glycerol triacetate, the composition is not in the form of a microemulsion pre- concentrate wherein the lipophilic component consists of one or a mixture of oils selected from triglycerides of medium chain fatty acid, mono- and di-glyceride and mono and di-acetylated monoglyceride and iii) the second component consists of N-methyl pyrrolidone, the composition is in the form of a microemulsion pre- concentrate or c) a second component comprising one or more of acetyl triethyl citrate polyethylene glycol glyceryl fatty acid ester, glyceryl di fatty acid ester, glyceryl mono fatty acid ester, a mixture of mono-, diglycerides of fatty acids, propylene glycol mono fatty acid ester, benzyl alcohol or a transesterification product of a natural or hydrogenated olive, almond, peanut, coconut, palm, palm kernel, soybean or wheat germ oil and a polyalkylene glycol and optionally glycerol; a lipophilic component and a surfactant, with the proviso that: i) the second component consists of acetyl triethyl citrate, the composition further comprises ethanol; ii) the second component consists of a mixture of mono-, diglycerides of fatty acids, the composition is free of fatty acid triglycerides and iii) the second component consists of a mixture of acetyl triethyl citrate and glycerol triacetate, the composition is not in the form of a microemulsion pre-concentrate wherein the lipophilic component consists of one or a mixture of oils selected from triglycerides of medium chain fatty acid, mono- and di-glyceride and mono and di-acetylated monoglyceride.
Patent NZ-509172-A (NZ)
Title: Antimalarial agents
Inventor: BERGERON RAYMOND J
IPC: A61K31/426
Filed: 1999-09-21
Abstract: Composition, article of manufacture for and method of treating malaria in a human having an infestation of Plasmodium protozoans are described. The method comprises administering a therapeutically-effective amount of a compound of formula (I), i.e. sufficient quantity to reduce the population of Plasmodium. The composition of the invention is a compound of formula (I) with a pharmaceutical excipient. The article of manufacture is the composition in combination with labeling for treating malaria. The substituents are detailed in the specification.
Patent NZ-510548-A (NZ)
Title: Optical fiber for extended wavelength band
Inventor: TIRLONI BARTOLOMEO ITALO
IPC: G02B6/02
Filed: 1999-09-21
Abstract: An optical transmission fibre for use in a wavelength division multiplexing transmission system is disclosed.  The transmission fibre includes an inner core surrounded by a first, second and at least a third glass layer along the length of the fibre.  The first glass layer has a depressed refractive-index difference and the second glass layer has a refractive-index difference of substantially zero.  The third glass layer has a positive refractive-index difference.  The fibre has an improved relationship between dispersion slope and depressed profile volume.  The fibre can have a dispersion value of at least 1.5 ps/nm/km and a dispersion slope of less than about 0.07 ps/nm2/km over an extended range of carrier wavelengths for the transmission system, such as the range 1450-1650 nm.
Patent NZ-510702-A (NZ)
Title: Aerosol generator with heater and methods of manufacture
Inventor: NICHOLS WALTER A
IPC: A24F40/70
Filed: 1999-10-14
Abstract: An aerosol generator includes a tube having a first and a second end, a heater arranged relative to the tube for heating the tube and a source of material to be volatilised, the second end of the tube being in communication with the source of material.  Also a valve operatively located between the source of material and the tube, the valve being openable and closeable to open and close communication between the source of material and the first end of the tube, and a pressurization arrangement for causing material in the source of material to be introduced into the tube from the source of material when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A method of making and a method of using an aerosol generator are also disclosed
Patent NZ-515175-A (NZ)
Title: Multi-purpose cap clip with fixing plates attachable to cap brim with at least one having holding device for accessory item
Inventor: YU-CHI TSAI
IPC: A42B1/24
Filed: 2001-11-01
Abstract: Fixing plates 12A, 12B, 12C, 13A, 13B, 13C, attach to cap 20. Holding devices 15A,16A,15B,16B,15C are inherently included in at least one fixing plate 12A,12B,12C for retaining accessory object 30,30A,30B.
Patent NZ-515580-A (NZ)
Title: Orally active A1 adenosine receptor agonists
Inventor: BLACKBURN BRENT K
IPC: C07H19/16
Filed: 2000-05-19
Abstract: Described are compounds of formula I and intermediate compounds of formula II, in which R1 is a 5-membered nitrogen or oxygen monoheterocycle and the remaining substituents are defined herein. The compounds of formula II are used in the manufacture of medicaments for treating diseases related to a coronary electrical disorder in a mammal.
Patent NZ-518392-A (NZ)
Title: Methods of asymmetrically synthesizing enantiomers of casodex, its derivatives and intermediates thereof
Inventor: EKWURIBE NNOCHIRI
IPC: C07D498/04
Filed: 2000-10-18
Abstract: A method of asymmetrically synthesising an enantiomer of an acylanilide or a derivative thereof, comprising: (a) contacting a compound having a ring structure that, when opened, provides a substituent of formula I, with a compound of formula II under sufficient conditions to provide a compound of formula III, and (b) treating the compound of formula III under conditions sufficient to provide a pure enantiomer of an acylanilide or a derivative thereof.
Patent NZ-520101-A (NZ)
Title: Treatment of obesity with a gene expressed in hypothalamus of obese animals
Inventor: ZIMMET PAUL ZEV
IPC: A61P3/00
Filed: 1998-10-30
Abstract: An isolated protein comprising and amino acid sequence as set for the in SEQ ID NO:2 or SEQ ID NO:14 or an amino acid sequence having at least 70% similarity to SEQ ID NO:2 or 14 after optimal alignment is used in the manufacture of a medicament for treating metabolic syndrome, dyslipidemia, hypertension, insulin resistance and to maintain weight.
Patent NZ-521467-A (NZ)
Title: Bactericidal preparation
Inventor: BOECK HARRY
IPC: A61K31/04
Filed: 2001-03-14
Abstract: A bactericidal preparation in the form of a solution, cream or ointment is disclosed, which comprises a bactericidally effective amount of a liquid compounded from photosynthesised hydrocarbons, isolates from hydrocarbons, 2-hydroxy-1-isopropyl-4-methyl-benzene (thymol) and butylated hydroxytoluene, the solution having the following composition by weight: a-pinene 1.9 to 2.0% a-terpinene 1.2 to 2.7% limonene 6.0 to 27.6% r-cymene 0.5 to 1.2% 1,8 cineole 2.5 to 25.6% g-terpinene 2.8 to 6.5% terpin-4-ol 4.0 to 20.0% g-terpineol 1.0 to 2.2% neral  2.2 to 9.2% geranial 1.5 to 11.5% thymol  0.3 to 2.0% euganol 0.5 to 3.5% butylated hydroxy toluene  0.3 to 0.5% balance is ethanol, provided these constituents are not derived or sourced from native New Zealand flora and fauna.
Patent NZ-521694-A (NZ)
Title: Container structure for removal of vacuum pressure
Inventor: MELROSE DAVID MURRAY
IPC: B65D1/02
Filed: 2002-09-30
Abstract: A hot-fill PET container or bottle (10) for filling with a liquid at an elevated temperature has a side wall (9) extending to a lower portion including a pressure panel (11) and a base (2) in its unfolded or pre-fill position. The panel (11) is transversely oriented and has a decoupling or hinge structure (13), an initiator portion (1) and control portion (5) of a steeply angled inverting conical section between 30 and 45 degrees. The control portion enables the inversion of the panel (11) into the container (10) to compensate for vacuum or reduced pressure induced within the container as the liquid cools down. The base (2) can also have a plurality of reinforcing ribs (3).
Patent NZ-524869-A (NZ)
Title: Food supplement
Inventor: HARRIS PATRICIA
IPC: A23L33/15
Filed: 2001-09-21
Abstract: Disclosed is a food supplement comprising one or more antioxidant vitamins with eugenol and/or a herbal phenolic, wherein a portion of the antioxidant vitamin is provided by a natural source and a portion of the antioxidant vitamin is provided by a synthetic source, when used in equines. Also disclosed is the use of one or more antioxidant vitamins with one or more of eugenol, a flavenoid, a phyto-estrogen, a proanthrocyandin, selenium, ubiquinone, a carotenoid, or a herbal phenolic in the manufacture of a medicament for the treatment of respiratory disease, wherein a portion of the antioxidant vitamin is provided by a natural source and a portion of the antioxidant vitamin is provided by a synthetic source.
Patent NZ-525146-A (NZ)
Title: System and method for hierarchical administration of complex item structures for on-line auction environments
Inventor: BROOKE STEVEN R
IPC: G06F3/0482
Filed: 2001-10-05
Abstract: A method is disclosed for administering complex item structures for an auction in a distributed computing environment. The method includes the steps of (a) defining at least one complex item and its subassemblies for auctioning to bidders, wherein each complex item includes several levels of subassemblies, (b) building a hierarchy for each complex item and its subassemblies, based on relationships between each complex and its subassemblies, (c) allowing access by a bidder to the hierarchy for each complex item and its subassemblies, for viewing the relationships between each complex item and its subassemblies, (d) receiving competing bids for each complex item and subassemblies from bidders, and (e) selecting at least one winning bid for each complex item and its subassemblies.