baber/WOPTO huggingface dataset:
Patent CA-2939058-A1 (CA)
Title: N2-phenyl-pyrido[3,4-d]pyrimidine-2,8-diamine derivatives and their use as mps1 inhibitors
Inventor: WOODWARD HANNAH
IPC: C07D519/00
Filed: 2015-02-27
Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1 also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
Patent CA-2939762-A1 (CA)
Title: Method and apparatus for a squeezable food container having a direct feeding tube connector
Inventor: GERWIRTZ GAIL
IPC: A61J15/00
Filed: 2015-02-09
Abstract: A sealed and squeezable container of pre-filled squeezable food that is sized no larger than a single meal serves as a prepackaged, one-time-use, meal-appropriate enteral food dispenser. By one approach the squeezable container has a dispensing port comprising a direct feeding tube connector. By one approach a flow limiter serves to limit a flow rate of the squeezable food from the squeezable container through the direct feeding tube connector. By another approach, in lieu of the foregoing or in combination therewith, a one-way valve can be disposed to prevent material (such as gas or other contents of the consumer's digestive system) from entering the squeezable container via the direct feeding tube connector.
Patent CA-2940758-A1 (CA)
Inventor: PORTERFIELD JOHN W
IPC: F17C13/04
Filed: 2014-04-22
Abstract: A threaded interface includes a male threaded body and a female threaded body.  The male threaded body includes a threaded section with external threads and a seal section with a plurality of o-rings seated circumferentially around the threaded body. The female threaded body includes a threaded section with internal threads and a seal section. The seal section of the female threaded body sealingly engages the o-rings of the seal section of the mail threaded body A pressure vessel and a pressure vessel assembly for an automatic fire extinguishing system incorporating the threaded interface are also disclosed.
Patent CA-2941654-A1 (CA)
Title: Insulin-like growth factor 1 receptor-specific antibodies and uses thereof
Inventor: STANIMIROVIC DANICA
IPC: C07K16/28
Filed: 2014-12-04
Abstract: The blood-brain barrier (BBB) prevents transport of molecules larger than 500 Dal tons from blood to brain. Receptor-mediated transcytosis (RMT) facilitates transport across the BBB of specific molecules that bind receptors on brain endothelial cells that form the BBB. An insulin-like growth factor 1 receptor (IGF lR)-binding antibody or fragment thereof is identified that transmigrates the BBB by RMT. The antibody or fragment is used to deliver a cargo molecule across the BBB, wherein the cargo molecule may be a therapeutic or detectable agent. The antibody is a camelid VHH, prepared by immunizing a llama with a 933-amino acid IGF 1R polypeptide. Humanized forms of the camelid VHH are also generated.
Patent CA-2943272-A1 (CA)
Inventor: SMITH DANIEL CHARLES
IPC: G06F3/0481
Filed: 2015-04-08
Abstract: Systems and techniques for supporting a veterinary practice are provided. Further, systems and techniques for the collection and display of animal wellness information are provided. Animal wellness data relating to a single animal patient or group of animal patients are collected and subsequently displayed at a desired remote location or on a mobile device so that a veterinarian can review the information.
Patent CA-2943564-A1 (CA)
Inventor: DONZIER ERIC
IPC: E21B49/00
Filed: 2014-12-05
Abstract: Probe (11) for producing signals (u(t)) indicative of a local phase composition (O, W) of a fluid (10) flowing in a well (51), comprising a body (13) of electrically insulating material having a tip (15) adapted for contact with the fluid (10), at least two electrodes (14a, 14b, 14c, 14d) of conductive material located in said body (13) on opposite sides relatively to a central axis (XX') of the body (13) and insulated from each other, said electrodes (14a, 14b, 14c, 14d) having ends exposed to the fluid (10) located on either side of said tip (15).
Patent CA-2945192-A1 (CA)
Title: Method, system, and computer program product for establishing a temporary remote control association between a mobile device and a peripheral device
Inventor: MILLS JAMES
IPC: G08C17/02
Filed: 2015-04-07
Abstract: The method can include the steps of: providing a local coordinator device having at least a first peripheral association data pertaining to the at least one peripheral device; seamlessly receiving the mobile credential from the at least one mobile device with the local coordinator device; validating the received mobile device credential; and subsequently to said validating, establishing the remote control association between the at least one mobile device and the at least one peripheral device using the first peripheral association data.
Patent CA-2946622-A1 (CA)
Title: Procedes et systemes de telemetrie sur un train de tiges de forage au moyen de sous-bandes acoustiques concomitantes
Inventor: SAED ARYAN
IPC: H04J11/00
Filed: 2015-04-21
Abstract: L'invention concerne un procédé de transmission de données dans un canal de communication sélectif en fréquence. Le procédé comprend : l'analyse de données devant être transmises dans une pluralité de champs de données; l'attribution des données de chaque champ de données dans l'une correspondant d'une pluralité de sous-canaux; la modulation des données de chacun de la pluralité de sous-canaux dans l'une correspondante d'une pluralité de sous-bandes, la pluralité de sous-bandes ayant des fréquences centrales espacées les unes des autres; et la transmission concomitante des données de la pluralité de sous-bandes via le canal.
Patent CA-2947592-A1 (CA)
Title: An exothermic massage implement comprising a reactant within a pouch
Inventor: YOUNG DANIEL
IPC: A61F7/00
Filed: 2010-07-26
Abstract: The present invention relates to an exothermic massage implement comprising a heat conducting vessel having an inner chamber surrounded by a wall with an inner surface and an outer surface; the wall comprising at least one aperture in the wall through which a liquid-permeable pouch can be inserted into the inner chamber of the vessel; aperture can be covered by a cap including a valve; and a reactant contained within a liquid-permeable pouch positioned inside the inner chamber of the vessel; wherein the reactant is an exothermic reactant adapted to generate an exothermic reaction upon contact with a liquid activator permeating the liquid-permeable pouch thereby combining the reactant and the activator to generate the exothermic reaction that releases heat, wherein the wall is heated with the released heat at a substantially constant elevated temperature for a duration of time.
Patent CA-2948705-A1 (CA)
Inventor: CHEN JOHNNY
IPC: F21K9/00
Filed: 2016-11-17
Abstract: A connector having enhanced protection against arcing during live or "hot"  connection of a plug assembly to a receptacle assembly. The terminals of the connector, including the connection point of exposed wiring, are electrically isolated from each other with dielectric barriers built in to the connector, such as polymer partitions. Accordingly, protection against arcing is provided in a connector that is assembled fast and inexpensively, without need for a time consuming installation of wire and terminal coatings or sleeves (e.g., "shrink tube"), and with greater reliability. The connector can be used in a modular system for decorative lighting and having a controller module that is not hard wired to a light string.  Use of the controller module independent of any of the light strings enables the controller to be used with any light string or with a replacement light string, in the event that the immediately connected light string fails.
Patent CA-2954436-A1 (CA)
Title: Cryoablation method and system
Inventor: MAHROUCHE RACHID
IPC: A61B18/02
Filed: 2015-06-15
Abstract: A system and method for providing greater control over the temperature of a thermal treatment element of a medical device, enabling an operator to extend a thawing period of a cryoablation procedure. The system may include a fluid flow path that bypasses a subcooler, giving the operator selective control over the temperature of refrigerant delivered to the treatment element and, therefore, treatment element temperature. Additionally or alternatively, the system may include a fluid delivery conduit that is in communication with a liquid refrigerant and a gaseous refrigerant. Adjustment of the ratio of liquid to gaseous refrigerant also offers control over the treatment element temperature.  Additionally or alternatively, the system may include one or more valves and/or heating elements in the fluid delivery and recovery conduits to control the treatment element temperature.
Patent CA-2955304-A1 (CA)
Inventor: HANOTIN CORINNE
IPC: A61K39/395
Filed: 2015-07-16
Abstract: The present invention provides methods for treating hypercholesterolemia. The methods of the present invention comprise administering to a high cardiovascular risk patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. The methods of the present invention are useful for treating high cardiovascular risk patients with hypercholesterolemia and established CHD or CHD risk equivalents that are not adequately controlled by maximum tolerated dose statin therapy.
Patent CA-2956897-A1 (CA)
Inventor: TRIEU VUONG
IPC: A61K31/18
Filed: 2015-06-08
Abstract: Methods for individualized therapy of arthritic pain using a non-steroidal anti-inflammatory drug (iCOX-2 inhibitor). Said methods comprise basing COX-2 inhibitor dose on each patient's pharmacokinetic response to said COX-2 inhibitor. Provided is a composition for treating pain without inducing edema comprising a COX-2 inhibitor and a diuretic, wherein the composition is administered in a fixed-dose combination.
Patent CA-2957073-A1 (CA)
Title: Ensemble d'additifs pour un lubrifiant pour engrenages industriels comprenant un composant soufre biodegradable
Inventor: BASU SHUBHAMITA
IPC: C10M135/06
Filed: 2015-08-06
Abstract: La présente technologie comprend un ensemble d'additifs résistant à des pressions extrêmes qui est formulé avec un composant soufré biodégradable, lequel ensemble d'additifs peut atteindre une efficacité à des pressions extrêmes appropriée lorsqu'il est formulé sous forme d'un lubrifiant pour une huile complètement formulée destinée à des engrenages industriels.
Patent CA-2957466-A1 (CA)
Inventor: AFTAB DANA T
IPC: A61P35/00
Filed: 2015-08-05
Abstract: This invention relates to the combination of a C-Met inhibitor and a proteasome inhibitor to treat cancer, particularly multiple myeloma.
Patent CA-2958135-A1 (CA)
Inventor: YBERT THOMAS
IPC: C12N15/10
Filed: 2015-09-01
Abstract: A modified nucleotide, intended for the synthesis of long chain nucleic acids by enzymatic processes, comprising a "natural" nitrogenous base or a natural nitrogenous base analogue, a ribose or deoxyribose carbohydrate, and at least one phosphate group, characterized in that said nucleotide comprises at least one R group, termed the modifier group, carried by said nitrogenous base or analogue and/or by the oxygen in position 3' of the ribose or deoxyribose molecule, making it possible to block the polymerization of said nucleotide and/or to allow the interaction of said nucleotide with another molecule, such as a protein, during the nucleic acid synthesis, R comprising at least one functional terminal group.
Patent CA-2958620-A1 (CA)
Inventor: STRUBE JOHN BRIAN
IPC: D04H1/00
Filed: 2015-09-03
Abstract: Nonwoven materials having discrete three-dimensional deformations therein forming protrusions that extend outward from the first surface of the nonwoven material and wide base openings adjacent to the second surface of the nonwoven material are disclosed. At least some of the three-dimensional deformations are configured to collapse in a controlled manner when compressive forces are applied on the nonwoven material.
Patent CA-2959112-A1 (CA)
Inventor: YOSHIMURA YASUO
IPC: A61B8/08
Filed: 2015-08-26
Abstract: To provide an ultrasonic urine volume measuring instrument that can highly accurately measure urine volume of a measurement subject and that is convenient for the measurement subject. There are provided a mode selector 22a capable of selecting one of a measurement mode of measuring urine volume while an ultrasound probe 10 is placed at a certain measurement position on the stomach of a measurement subject, and a positioning mode of measuring urine volume while moving the ultrasound probe 10 to a plurality of tentative measurement positions on the stomach in order to determine the measurement position suitable for placing the ultrasound probe 10 in the measurement mode; and an index value memory 23a that stores a maximum value among urine volumes at the plurality of tentative measurement positions, calculated by the arithmetic unit 24, while the positioning mode is being selected, and/or an allowance value determined on the basis of the maximum value. The maximum value and/or the allowance value is displayed, on a graph on a display unit 27, as a positioning index value for positioning the ultrasound probe 10.
Patent CA-2961304-A1 (CA)
Title: Procede de fabrication d'un corps de mandrin a poche laterale
Inventor: PETTERSEN STALE
IPC: E21B23/02
Filed: 2015-10-29
Abstract: L'invention concerne un procédé de fabrication d'un corps de mandrin à poche latérale (1), destiné à être utilisé dans un ensemble mandrin à poche latérale de puits d'hydrocarbures, ledit corps de mandrin comprenant: une première extrémité (2) pour présenter un premier agencement de liaison (3) afin de relier le corps de mandrin à une section montante d'une colonne de production du puits d'hydrocarbures, et une seconde extrémité (4) pour présenter un second agencement de liaison (5) afin de relier le corps de mandrin à une section de fond de trou de la colonne de production ; un conduit principal traversant, longitudinal (6) pour communiquer avec un passage central de la colonne de production ; une section de poche latérale (7) comportant au moins une poche latérale (8) pour recevoir de manière récupérable un dispositif de commande d'écoulement de fluide d'injection. Le procédé comprend les étapes consistant : à fournir un morceau de matière solide et continu avec le conduit principal traversant ; dans le morceau de matière solide, à former ladite ou lesdites poches latérales par usinage d'un alésage (21), à exposer une ouverture d'entrée externe (23), dans une section décalée latéralement du morceau de matière solide généralement parallèle au conduit principal, de telle sorte qu'une section de paroi interne (9) du morceau de matière solide est amenée à séparer le conduit principal de l'alésage usiné ; à obturer l'ouverture d'entrée (23) de l'alésage usiné avec un bouchon étanche aux fluides (20) ; à fournir au moins une ouverture (16) à partir d'un extérieur du corps du mandrin dans la ou les poches latérales, formant ainsi une entrée de fluide d'injection ; à fournir au moins une ouverture dans la section de paroi, formant ainsi une sortie de fluide d'injection ; à fournir le morceau de matière solide avec les premier et second agencements de liaison, amenant ainsi le corps de mandrin à pouvoir être relié aux sections montante et de fond de trou de la colonne de production.
Patent CA-2963954-A1 (CA)
Inventor: SALOMAN CHRISTOPHER
IPC: H04N5/268
Filed: 2015-10-07
Abstract: The invention relates to a device (100) for generating a video output data stream by shifting from a first video input data stream to a second video input data stream The device (100) comprises an interface (110) for receiving encoded video frames of a first video input data stream. The interface (110) is designed to receive a shift command, instructing a shift to the receiving of encoded video frames of the second video input data stream. The interface (110) is also designed to send a request command, after receiving the shift command, requesting the transfer of one of the encoded intra-frames of the second video input data stream. According to an arrival of one of the intra-frames of the second video input data stream at the interface (110), a video data stream generator (120) is designed to emit this intra-frame and the encoded video frames of the second video input data stream, received by the interface (110) after the arrival of this intra-frame, as video frames of the video output data stream.
Patent CA-2964682-A1 (CA)
Title: Apparatus and method for controlling the orientation of a suspended load
Inventor: JAMIESON ANGUS
IPC: B66C13/08
Filed: 2014-10-24
Abstract: The invention provides an apparatus [10] and method for controlling the orientation of a suspended load. The apparatus consists of a closed loop pipe [11] containing a fluid volume attachable to a suspended load and at least one pump for circulating the fluid volume in the pipe. A control unit [17] is operable to receive at least one input direction signal. The apparatus includes a control unit which is configured to generate a control signal to the at least one pump to control the flow of the fluid volume in the pipe and thereby impart a rotational force on the pipe.
Patent CA-2965870-A1 (CA)
Title: Energy storage devices and methods of production thereof
Inventor: LAZAREV PAVEL IVAN
IPC: H01G4/00
Filed: 2015-11-03
Abstract: The present disclosure provides an energy storage device comprising a first electrode, a second electrode, and a solid multilayer structure disposed between said first and second electrodes. The solid multilayer structure can be in contact with said first and second electrodes. The solid multilayer structure can include layers disposed parallel to said electrodes, the layers have a sequence (A-B)m-A, wherein, A is an insulating layer and B is a polarization layer comprising a colloidal composite with a micro-dispersion of electro-conductive nano-particles in an insulator matrix, and 'm' is a number greater than or equal to 1. Layer A can have a breakdown voltage of at least about 0.05 volts per nanometer (nm), and layer B can have a dielectric permittivity of at least about 100.
Patent CA-2966233-A1 (CA)
Inventor: GUERRY BRIAN ROBERT
IPC: B65D21/032
Filed: 2017-05-04
Abstract: A tray includes a base having an upper support surface and a central portion extending downward to define a lowermost surface of the tray. The base includes a peripheral portion recessed relative to the central portion. A pair of opposed first walls extend along opposed first edges of the base. A pair of opposed second walls extending along opposed second edges of the base.
Patent CA-2967351-A1 (CA)
Title: Enrichissement polynucleotidique a l'aide de systemes crispr-cas
Inventor: MANDELL JEFFREY G
IPC: C12N15/90
Filed: 2015-11-10
Abstract: L'invention concerne un procédé d'amplification d'un acide nucléique cible comprenant la fourniture d'un système ARNcr ou un dérivé de celui-ci, et une protéine Cas ou un variant de celle-ci. L'ARNcr ou le dérivé de celui-ci contient une région nucléotidique spécifique d'une cible sensiblement complémentaire d'une région de l'acide nucléique cible; et le procédé consiste à mettre en contact l'acide nucléique cible avec le système pour former un complexe.
Patent CA-2967522-A1 (CA)
Title: Calcium sulphase-based products
Inventor: BROOKS LAURA
IPC: C04B28/14
Filed: 2015-11-17
Abstract: The present invention relates to a calcium sulphate-based product (e.g. a wallboard) comprising gypsum and a shrinkage resistance additive. The shrinkage resistance additive is a metal nitrate, hydroxide, acetate or sulphate and is preferably provided in an amount greater than 4 wt% (based on the amount of additive and gypsum). The additive may be a nitrate of an alkali metal (e.g. potassium), an alkaline earth metal (e.g. magnesium or calcium), a transition metal (e.g. iron or zinc) or aluminium.
Patent CA-2967756-A1 (CA)
Inventor: TORCH WILLIAM C
IPC: G02B27/00
Filed: 2005-04-01
Abstract: Biosensor, communicator, and/or controller apparatus, systems, and methods are provided for monitoring movement of a person's eye. The apparatus includes a device configured to be worn on a user's head, a light source for directing light towards one or both eyes of the user, one or more image guides on the device for viewing one or both eyes of the user, and one or more cameras carried on the device and coupled to the image guides for acquiring images of the eyes and/or the user's surroundings. The apparatus may include a cable and/or a transmitter for transmitting image data from the camera to a remote location, e.g., to processor and/or display for analyzing and/or displaying the image data. A system including the apparatus may be used to monitor one or more oculometric parameters, e.g., pupillary response, and/or to control a computer using the user's eyes instead of a mouse.
Patent CA-2968619-A1 (CA)
Inventor: ZHAO WEI
IPC: H02M7/42
Filed: 2017-05-30
Abstract: A central-string inverter device is provided, including a container and multiple string inverters installed in the container. The multiple string inverters are arranged in two rows located respectively on two opposite sides of the container. An intermediate duct is formed between the two rows of string inverters. An air outlet is arranged on each of side walls of the two opposite sides of the container. An air inlet is arranged on each of side walls of the other two opposite sides of the container or on a bottom wall of the container. Pulling structures corresponding to the multiple string inverters are arranged on the side walls of the two opposite sides of the container. Each string inverter is installed or removed through the pulling structure. The central-string inverter device according to the present disclosure has 20 or more MPPTs. In addition, since the string inverters are integrated into a container, the installation, maintenance and heat radiation is a big issue. The central-string inverter device according to the present disclosure can be easily installed, maintained and is advantageous for heat radiation.
Patent CA-2969823-A1 (CA)
Title: Topical skin care formulations comprising plant extracts
Inventor: FLORENCE TIFFANY
IPC: A61K8/9789
Filed: 2010-08-26
Abstract: Ageing, chronic exposure to adverse environmental factors, malnutrition, fatigue, etc., can change the visual appearance, physical properties, or physiological functions of skin in ways that are considered visually undesirable. Disclosed are compositions and corresponding methods of their use that include extracts from the whole plant of Loropetalum chinensis, Trema angustifolia, and Glochidion lanceolaris, or any combination thereof.  The use of a composition comprising an aqueous abstract from the whole plant of Loropetalum chinensis, Trema angustifolia, and Glockdion lanceolaris, or any combination thereof for inhibiting at least one of tyrosinase activity, elastase activity, and TNF-.alpha. activity in the skin and the use of a composition comprising an aqueous abstract from Loropetaluin chinensis for reducing oxidation, tyrosinase activity, elastase activity, or tumor necrosis factor alpha (TNF-.alpha.) activity in the skin are also disclosed.