baber/WOPTO huggingface dataset:
Patent EP-1163238-B1 (EP)
Inventor: BRIDGER GARY
IPC: C07D417/14
Filed: 2000-03-24
Granted: 2006-05-31
Abstract: La présente invention concerne une nouvelle classe de composés hétérocycliques se liant aux récepteurs de chimiokine et inhibant de ce fait la liaison de leurs ligands naturels. Ces composés ont un effet protecteur contre l'infection par VIH grâce à leur liaison aux récepteurs de chimiokine, y compris CXCR4 et CCR5, inhibant ainsi la liaison par ces chimiokines. La présente invention concerne un composé représenté par la formule (I)  dans laquelle W désigne un atome d'azote et Y est absent ou W désigne un atome de carbone et Y = H ; R1 à R7 peuvent être les mêmes ou être différents et sont indépendamment sélectionnés entre un hydrogène ou un alkyle en C¿1-6? droit, ramifié ou cyclique ; R?8¿ représente un groupe hétérocyclique substitué ou un groupe aromatique substitué ; Ar représente un cycle aromatique ou hétéroaromatique chacun éventuellement substitué à une position unique ou à des positions multiples, non liantes par des groupes donneurs d'électrons ou des groupes suppresseurs ; n et n' désignent indépendamment 0 à 2 ;  X désigne un groupe représenté par la formule (a) ou (b) dans lesquelles le cycle A désigne un cycle à 5 ou 6 chaînons saturé ou insaturé et éventuellement substitué et P désigne un atome de carbone éventuellement substitué, un atome d'azote éventuellement substitué, un atome de soufre ou un atome d'oxygène. Le cycle B désigne un cycle de 5 à 7 chaînons éventuellement substitué. Le cycle A et le cycle B de la formule précédente peuvent être reliés au groupe W à partir de n'importe quelle position en passant par le groupe V, V représentant une liaison chimique, un groupe en (CH¿2?)n'' (dans lequel n'' = 0-2) ou un groupe C=O. Z représente (1) un atome d'hydrogène, (2) un groupe alkyle en C1-6 éventuellement substitué, (3) un groupe alkyle en C0-6 substitué par un groupe aromatique ou hétérocyclique éventuellement substitué, (4) un alkylamino en C0-6 éventuellement substitué ou un groupe cycloalkylamino en C3-7, (5) un groupe carbonyle ou un sulfonyle éventuellement substitué. Ces composés comprennent également n'importe quel sel d'addition acide acceptable du point de vue pharmaceutique de ces composés ainsi que leurs complexes métalliques et n'importe quelle forme stéréoisomère et mélange de formes stéréoisomères de ces composés.
Patent EP-1161427-B1 (EP)
Inventor: HEWITT BRADLEY D
IPC: A61K31/4433
Filed: 2000-03-14
Granted: 2002-10-23
Abstract: The present invention is a process for the preparation of a compound of the formula:where R3, R4 and n are defined in the specification which comprises hydrogenating a compound of the formula:the E-geometrical isomer thereof or a mixture of the Z- and E-isomers in the presence of catalyst containing Rh, a chiral ligand with at least one phosphorous atom where the hydrogenation is conducted in the presence of a base.
Patent EP-1192355-B1 (EP)
Title: Eolienne avec regulation du niveau sonore
Inventor: WOBBEN ALOYS
IPC: F03D7/00
Filed: 2000-03-11
Granted: 2004-11-10
Abstract: L'invention concerne un procédé permettant à un système de turbines éoliennes de respecter le niveau sonore maximal admis selon la législation sur les nuisances. Ce procédé consiste tout d'abord à réduire la vitesse de rotation du rotor de la turbine dès que des valeurs prescrites pour le niveau sonore, la vitesse du vent, le sens du vent et les horaires sont atteintes. Il consiste également à installer une turbine éolienne, dont la vitesse de rotation n'est pas réduite, du côté abrité d'une première turbine éolienne à vitesse de rotation réduite.
Patent EP-1181207-B1 (EP)
Inventor: DAMBRICOURT GERY BERNARD MARIE
IPC: B65D35/02
Filed: 2000-04-20
Granted: 2003-08-27
Abstract: The invention concerns a packaging tube for pasty product, comprising a tubular skirt extending along an axial direction and sealed by swaging at the end of the tube, and a head located at the other end of the tube, the head including a dispensing passage and a neck forming a radial extension of the dispensing passage, the neck being connected to the skirt by a connecting surface. The skirt and the connecting surface have, respectively, a circumference and a radius of curvature such that the ratio of the circumference over the radius is not more than 20.
Patent EP-1175548-B1 (EP)
Inventor: MASON DAVID B
IPC: E21B19/16
Filed: 2000-05-02
Granted: 2003-08-06
Abstract: An iron roughneck has a pair of upper jaws carrying pipe gripping dies for gripping tool joints. The jaws have recesses formed on each side of the pipe gripping dies to receive spinning rollers. By positioning the spinning rollers in the upper jaws at the same level as pipe gripping dies, the spinning rollers are able to engage the pipe closer to the lower jaws and thus can act on the tool joint rather than on the pipe stem.
Patent EP-1180168-B1 (EP)
Inventor: BAENS MATTHIJS
IPC: C12Q1/68
Filed: 2000-05-26
Granted: 2004-11-17
Abstract: The invention discloses means and methods for determining whether a tissue sample or an analogue and/or derivative thereof comprises a cell with a chromosome {11:18} translocation associated with malignancies such as mucosa-associated lymphoid tissue (MALT) lymphoma's. The invention further provides insight into a novel mechanism of transformation of primary cells. Said mechanism involving expression of a fusion proteinaceous molecule comprising at least apoptosis inhibitor 2 (API2) or a functional part, derivative and/or analogue thereof fused to at least one other proteinaceous molecule. The invention also provides a novel nucleic acid sequence and proteinaceous molecule expressed from said sequence termed MALT-lymphoma associated Translocation (MLT) protein.
Patent EP-1287152-B1 (EP)
Inventor: BUCHHOLZ URSULA
IPC: C12N15/86
Filed: 2000-06-23
Granted: 2008-12-31
Abstract: Chimeric human-bovine respiratory syncytial virus (RSV) are infectious and attenuated in humans and other mammals and useful in vaccine formulations for eliciting an anti-RSV immune response. Also provided are isolated polynucleotide molecules and vectors incorporating a chimeric RSV genome or antigenome which includes a partial or complete human or bovine RSV “background” genome or antigenome combined or integrated with one or more heterologous gene(s) or genome segment(s) of a different RSV strain. In preferred aspects of the invention, chimeric RSV incorporate a partial or complete bovine RSV background genome or antigenome combined with one or more heterologous gene(s) or genome segment(s) from a human RSV. A variety of additional mutations and nucleotide modifications are provided within the human-bovine chimeric RSV of the invention to yield desired phenotypic and structural effects.
Patent EP-1189656-B1 (EP)
Inventor: PALASIS MARIA
IPC: A61L31/10
Filed: 2000-06-02
Granted: 2007-09-19
Abstract: Medical devices and systems for the localized delivery of genetic information to a target location within a mammalian body. In one embodiment, the system comprises a medical device insertable into the body and a biostable coating over at least part of the medical device. Genetic information is incorporated into the biostable coating before the medical device is placed into the body, and is released from the biostable coating at a target location within the body. The invention also includes methods for the localized delivery of genetic information to target locations within a mammalian body using the medical devices and systems of the invention.
Patent EP-1204345-B1 (EP)
Inventor: VETTER JACQUES
IPC: A47G1/06
Filed: 2000-08-04
Granted: 2003-04-16
Abstract: The invention concerns a device for presenting two-dimensional objects such as photographs, drawings or reproductions, comprising a frame (5), having a front face and a rear face, the rear face including on its internal edge a rabbet (6) wherein are designed to be placed a transparent plate (10) and a rigid and opaque backing plate (12), a two-dimensional object (11) to be displayed being inserted between said two plates and clamping means being provided to press the backing plate against the rabbet (6). The invention is characterised in that the frame (5) has positioning means located away from the rabbet (6) on the side of the front face of the frame, and the device comprises a second transparent plate (8) designed to be maintained by said positioning means and decorative three-dimensional objects (9) are placed in the gap between the two transparent plates.
Patent EP-1226539-B1 (EP)
Inventor: COCOLA ADRIANO
IPC: G06F19/00
Filed: 2000-09-12
Granted: 2006-11-29
Abstract: A data processing system for data management in an analytical laboratory is described, and comprises, in combination, a central electronic computer (1) for acquiring the patient data, and for generating a patient code (CP) for each patient acquired; means (15) for acquiring an identification code (CI) associated with each container (13) for laboratory analysis; means (17) for combining each of said acquired identification codes with a corresponding patient code; at least one analyzer (7; 9) which carries out at least one analysis on a biological specimen contained in the containers placed in it.
Patent EP-1218361-B1 (EP)
Inventor: CHENG PETER T W
IPC: A61K45/00
Filed: 2000-09-19
Granted: 2009-01-07
Abstract: Compounds are provided which have structure (I), wherein Q is C or N; A is O or S; Z is O or a bond; X is CH or N and R?1, R2, R2a, R2b, R2c, R3¿, Y, x, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.
Patent EP-1231902-B1 (EP)
Inventor: BUISSON BERTRAND
IPC: A61K47/44
Filed: 2000-11-09
Granted: 2005-03-09
Abstract: The invention concerns a film coating method for tablets, characterised in that in consists in spraying on said tablets a film coating agent suspended in a fluid with supercritical pressure. The inventive method consists in continuously spraying in a film coating drum whereof the axis inclined relative to the horizontal enables a continuous circulation of tablets introduced upstream and at the top part of said drum, and after the film coating process, collected downstream and at the bottom part of said drum.
Patent EP-1231141-B1 (EP)
Inventor: THIEME HANS-DIETER
IPC: B65B13/34
Filed: 2001-02-12
Granted: 2006-01-18
Abstract: The system for fitting a band (9) around a cable harness comprises a clip (2), through which the band is fed as a loop. The band first passes through jaws (7) and a swivelling plate (6) above the band periodically prevents one end (21) of the clip from fastening.
Patent EP-1153924-B1 (EP)
Inventor: MANSOUR TAREK
IPC: C07D411/04
Filed: 1995-04-19
Granted: 2004-09-01
Abstract: This invention relates to single enantiomers of novel cis-substituted 1,3-oxathiolanes, of formula (I) wherein R1 is hydrogen, and R2 is cytosine or 5-fluorocytosine, and pharmaceutically acceptable salts and esters thereof. This invention also relates to pharmaceutical compositions containing them and to the use of these compounds as antiviral agents, particularly in combination therapy.
Patent EP-1202187-B1 (EP)
Inventor: LIU WEN-YIN
IPC: G06T1/00
Filed: 2001-10-18
Granted: 2007-08-01
Abstract: An image retrieval system performs both keyword-based and content-based image retrieval. A user interface allows a user to specify queries using a combination of keywords and examples images. Depending on the input query, the image retrieval system finds images with keywords that match the keywords in the query and/or images with similar low-level features, such as color, texture, and shape. The system ranks the images and returns them to the user. The user interface allows the user to identify images that are more relevant to the query, as well as images that are less or not relevant to the query. The user may alternatively elect to refine the search by selecting one example image from the result set and submitting its low-level features in a new query. The image retrieval system monitors the user feedback and uses it to refine any search efforts and to train itself for future search queries. In the described implementation, the image retrieval system seamlessly integrates feature-based relevance feedback and semantic-based relevance feedback. <IMAGE>
Patent EP-1206948-B1 (EP)
Inventor: GANSHORN PETER DIPL-ING
IPC: A61M15/00
Filed: 2001-11-07
Granted: 2005-01-26
Abstract: Device for removal of gas from a patient's breath or delivery of gas to the breath has a breathing tube (4) with a mass- flowmeter (11). In addition, connections (5, 6) can be made to gas container (2). The latter has a piston (1) that is moved by a servomotor operated by a control unit. Control of piston movement is such that piston velocity is proportional to the airflow in the breathing tube.
Patent EP-1221525-B1 (EP)
Inventor: MUELLER WERNER
IPC: E06B3/30
Filed: 2001-12-20
Granted: 2004-05-19
Abstract: A wood-aluminium window consists of aluminium on the outside of a wooden frame. The aluminium shell is filled with a plastic foam, especially PU foam, which is in contact with the wood, and the plastic foam lining (13,14) has fixing rails (19,20) which accommodate T-shaped holders. The plastic rails have a C-profile and the inner surface of the plastic foam lining has an overlapping cover shank.
Patent EP-1147787-B1 (EP)
Inventor: BOSTOCK GRAHAM J
IPC: A62B23/02
Filed: 1996-03-08
Granted: 2010-06-16
Abstract: Fold-flat personal respiratory protection devices (10,50) are provided. The devices have a central panel (12,52) having first and second edges, a first panel (14,54) joined to the first edge of the central panel through either a fold-line (15,55), seam, weld or bond, said fold, bond, weld or seam of the first panel being substantially coextensive with said first edge of said central panel, and a second panel (16,56) joined to the second edge of the central panel through either a fold-line, seam, weld or bond, the fold, bond, weld or seam (17,57) of the second panel being substantially coextensive with said second edge of said central panel. The central and first and second panels are formed from filter media. The device is capable of being folded flat for storage with the first and second panels being in at least partial face-to-face contact with a common surface of the central panel and, during use, is capable of forming a cup-shaped air chamber over the nose and mouth of the wearer with the unjoined edges of the central portion and first and second panels adapted to contact and be secured to the nose, cheeks and chin of the wearer.
Patent EP-1389401-B1 (EP)
Inventor: WAWRZYNSKI PAWEL
IPC: H04W16/18
Filed: 2001-12-04
Granted: 2006-10-25
Abstract: The method consists in the use of the average network traffic data and a series of measurements taken within a part of a network, along with the recording of the signals, received from all base stations within reach of a given point. The measurement area is divided into polygonal sections, relating to specific P measurements and the total area of such section represents the weight of a given measurement. Subsequently, based on the most powerful signal criterion, individual P measurements are assigned to specific network cells. Further on, the based on the differences between signal power value calculated, measurement weights and the assumed distances between channels, values of certain formulae are calculated, which then provide the basis for determination of the minimum distances between channels.
Patent EP-1267975-B1 (EP)
Inventor: HUXHAM LAURENCE S
IPC: A61M15/00
Filed: 2001-03-16
Granted: 2006-08-02
Abstract: An inhaler for delivery of medicament from a canister which is compressible to deliver a dose of medicament. The inhaler comprises a housing 1 for holding a canister 2, the housing having a mouthpiece 5 for inhalation of a dose of medicament delivered by the canister 2 and a breath-actuated actuation mechanism 6 for compressing a canister 2 held in the housing 1 in response to inhalation at the mouthpiece 5. The actuation mechanism 6 includes a vane in the form of a flap 13 disposed across a duct 24, 32 extending from the mouthpiece 5 arranged to lock the canister 2 in a compressed state and being responsive to the inhalation at the mouthpiece 5 to release the canister 2 when the level of inhalation at the mouthpiece falls below a predetermined threshold.
Patent EP-1272251-B1 (EP)
Inventor: SALO RODNEY W
IPC: A61N1/362
Filed: 2001-03-30
Granted: 2005-02-09
Abstract: A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.
Patent EP-1294664-B1 (EP)
Inventor: ZELLER EDGAR
IPC: C07C43/04
Filed: 2001-06-25
Granted: 2005-11-02
Abstract: The present invention relates to an alcohol mixture which substantively comprises alcohols having 13 or 15 carbon atoms, to a process for its preparation, to a process for functionalizing these alcohol mixtures, and to the resultant functionalized alcohol mixtures and their use.
Patent EP-1311634-B1 (EP)
Inventor: NOWAK MICHAEL T
IPC: B43K7/02
Filed: 2001-08-20
Granted: 2007-03-28
Abstract: La présente invention concerne une composition d'encre fluorescente non aqueuse destinée à des instruments d'écriture, qui comprend une dispersion de pigments fluorescents et un solvant organique à point d'ébullition élevé. Cette composition d'encre peut aussi comprendre des résines, des plastifiants, des agents empêchant la formation de peaux, des lubrifiants et des stabilisants. Cette composition d'encre fluorescente présente un aspect brillant de sa couleur dans la masse et sur le papier.
Patent EP-1409852-B1 (EP)
Inventor: MENDLER EDWARD CHARLES
IPC: F01L1/34
Filed: 2001-09-14
Granted: 2006-05-24
Abstract: L'invention porte sur un système de commande de soupapes comportant un premier arbre à cames (24) commandant les soupapes d'échappement (18) et une première soupape d'admission (12) de chacun des cylindres (8), un deuxième arbre à cames (38) commandant la deuxième soupape d'admission de chaque cylindre (14), et en outre un déphaseur (62) réglant le décalage angulaire du deuxième arbre à cames (38) par rapport au premier (24). Les soupapes d'échappement et la première soupape d'admission sont actionnées par des culbuteurs (30),(36), dont celui (36) de la première soupape d'admission, court et léger, peut fonctionner à la vitesse maximale (36) et avec un faible frottement. Le premier arbre à cames (24) est placé au dessus des culbuteurs, les poussoirs sont placés sensiblement au milieu des culbuteurs (30),(36) et les supports des culbuteurs (33),(35) sont placés aux extrémités intérieures des culbuteurs, ce qui donne des culbuteurs légers, à faible angle de pivotement, et à faible frottement avec les tiges de soupape.
Patent EP-1346124-B1 (EP)
Inventor: BARENDT LEIF
IPC: E05F15/20
Filed: 2001-11-14
Granted: 2005-12-21
Abstract: A method and an apparatus in clamp protection systems (1-3) for doors and eventually existing footsteps (7) cooperating therewith, comprising a digital camera (4) at actual doors (1-3), which camera (4) is connected to a central computer (5) having a monitoring screen (5) to which also the ordinary opening and closing electronic means (6) are connected. Each camera transmits images at short intervals to the monitoring screen (5), each image is frequently compared with a reference image stored in the monitoring screen (5), and whereby alarm is given as soon as an image received from a camera (4) differs from the reference image of the monitoring screen (5), whereby the door (1-3) in question is opened or is maintained closed until the monitoring screen (5) observes that the received image coincides with the reference image.
Patent EP-1349736-B1 (EP)
Inventor: BLOCK WOLFGANG
IPC: A61G7/05
Filed: 2001-12-10
Granted: 2006-06-14
Abstract: Roller ( 1 ), particularly a castor-type roller, with rotational movement of a running wheel ( 12 ), with an operating shaft ( 20 ) which passes through a control cam ( 19 ) of the roller ( 1 ) and on which an electric motor ( 37 ) acts via a gear mechanism to operate it, wherein the electric motor ( 37 ) acts on the operating shaft ( 20 ) by means of an electric motor shaft ( 39 ) via a toothed gear mechanism ( 38 ), the toothed gear mechanism ( 38 ) having a driven gear wheel ( 41 ), a hub ( 40 ) of which is passed through by the operating shaft ( 20 ).
Patent EP-1348088-B1 (EP)
Inventor: WALKER DANIEL H
IPC: A61M39/00
Filed: 2001-12-03
Granted: 2006-05-10
Abstract: Raccord rapide comprenant un composant mâle ayant la forme générale d'une bobine, monté fixé sur une conduite de fluide, et un composant femelle ayant la forme d'un bloc présentant un trou, ouvert à une extrémité, en vue de loger le composant mâle. Un loquet est monté rotatif sur la bobine et peut se déplacer, par rapport à un canal transversal ménagé dans le composant femelle, entre une première position, de montage, par rapport au canal, et une seconde position, verrouillée, dans laquelle le loquet s'engage dans des encoches opposées, de manière à bloquer la bobine dans ledit bloc. Au moins une bague de verrouillage est montée sur le loquet de manière à pouvoir coopérer avec les bords du canal du corps en vue de s'opposer à la rotation du loquet à partir de sa position verrouillée. On peut prévoir une bague secondaire, susceptible de coopérer avec la bague du loquet, le loquet et les bords latéraux opposés du canal, en vue de s'opposer davantage à la rotation du loquet à partir de sa position verrouillée.
Patent EP-1227308-B1 (EP)
Inventor: LAVENUTA GREGG
IPC: G06F3/02
Filed: 2002-01-25
Granted: 2006-04-12
Abstract: A thermistor having multiple metal layers about at least a portion of a semiconductor body. The thermistor includes a first thick film electrode layer, a reactive metal layer, a barrier metal layer and, optionally, a layer to facilitate attachment to an electrical contact. Also, a method of making the thermistor is described. <IMAGE>
Patent EP-1243763-B1 (EP)
Inventor: CHIAPPINI STEFANO
IPC: F01L13/00
Filed: 2002-03-18
Granted: 2004-08-18
Abstract: In an internal-combustion engine with a hydraulic system for variable operation of the valves, associated to the tappet controlled by each cam of the cam shaft is a passage (100) for bleeding the hydraulic system. <IMAGE>
Patent EP-1323505-B1 (EP)
Title: Method and apparatus for cutting prepreg
Inventor: KAJI YOSHIYUKI
IPC: B23K26/00
Filed: 2002-06-25
Granted: 2005-08-17
Abstract: A prepreg cutting method is provided that cuts prepreg (1) without applying any processing, such as heating, to that part of prepreg other than the place to be cut. When prepreg (1) formed by impregnating a base material with a resin and left to semi-harden is to be cut into a specified dimension, the surface of the prepreg (1) is irradiated with a laser beam (L) so that the resin of the irradiated portion is softened while the laser beam irradiating position is shifted on the prepreg, and the softened resin part is cut by a cutting blade (2). Because the cutting blade (2) cuts the prepreg portion where the resin has softened, resin dust will not scatter. <IMAGE>
Patent EP-1293365-B1 (EP)
Inventor: ZAWADZKI BERND
IPC: B60G11/12
Filed: 2002-07-27
Granted: 2004-05-19
Abstract: The spring eye fitting has a rubber body (4) with a free circumferential surface. it can be pressed into an unmachined spring eye (5) so that this circumferential surface fits directly in the spring eye. The annular resting surfaces (6) of the support rings (7) have at least one rubber receiving cavity in the form of a notch.