baber/WOPTO huggingface dataset:
Patent WO-2019018445-A1 (WO)
Title: Polytherapy modulating cathelicidin gene expression modulation for the treatment of alzheimer's disease and other conditions
Inventor: BARRON ANNELISE E
IPC: A61K31/12
Filed: 2018-07-17
Abstract: A polytherapy of orally available compounds is disclosed that synergistically modulates and induces the expression of the cathelicidin gene (CAMP), which encodes the host defense peptide LL-37. By providing a number of different CAMP-inducing compounds together at the same time, stronger gene induction is achieved than with just one or two compounds. Induction also may vary in different parts of the body, depending on which compounds are used and at what levels.The polytherapy may induce cathelicidin expression in the brain, which may help to treat or prevent Alzheimers Disease. Systemic cathelicidin gene induction may help treat numerous other conditions including Type 2 Diabetes / Metabolic Syndrome, or chronic bacterial, viral, or fungal infections associated with increased cancer risk or neurodegeneration. By increasing cellular autophagy and macroautophagy and supporting mitochondrial biogenesis and homeostasis, CAMP gene upregulation may reduce the effects of cellular aging and increase longevity.
Patent WO-2019023047-A1 (WO)
Title: Heated patient tube assembly
Inventor: NORMAN SCOTT
IPC: A61M39/00
Filed: 2018-07-20
Abstract: A heated patient tube assembly that carries and warms fluids to a desired temperature includes an elongated hollow tube and a heating assembly at least partially embedded within the tube for heating the tube and fluids carried in the tube. The heated patient tube assembly can be selectively used in any combination of three different modes: a first mode in which the heating assembly is connected to a control assembly, a second mode in which the heating assembly is powered wirelessly, and a third mode in which the tube is inserted into and heated by an external warming device.
Patent WO-2019023125-A1 (WO)
Title: Systems and methods for protecting display merchandise from theft
Inventor: GRANT JEFFREY
IPC: G08B13/12
Filed: 2018-07-23
Abstract: Security systems and methods for protecting retail display merchandise from theft are provided. For example, a security system includes a sensor configured to operably engage an item of merchandise and a monitoring component configured to wirelessly communicate with the sensor. The monitoring component and the sensor are configured to be paired with one another using a unique identifier for communicating with one another, and the monitoring component and/or the sensor is configured to initiate a security signal when the monitoring component and/or the sensor fails to receive a signal from one another.
Patent WO-2019027745-A1 (WO)
Title: Mri-safe and force-optimized implantable ring magnet system with an enhanced inductive link
Inventor: EIGENTLER THOMAS WILHELM
IPC: A61N1/375
Filed: 2018-07-25
Abstract: A magnetic system for a medical implant system is described. A planar implant receiver coil is configured to lie underneath and parallel to overlying skin of an implanted patient for transcutaneous communication of an implant communications signal. A planar ring-shaped attachment magnet also is configured to lie underneath and parallel to the overlying skin and radially surrounds the receiver coil. The attachment magnet is characterized by a magnetic field configured to avoid creating torque on the attachment magnet in the presence of an external magnetic field.
Patent WO-2019112650-A1 (WO)
Title: Comparaison biométrique de protection de confidentialité assistée par serveur
Inventor: SHEETS JOHN F
IPC: H04W12/06
Filed: 2018-07-25
Abstract: L'invention concerne un système et des techniques pour permettre une authentification biométrique sans exposer l'entité d'autorisation à des informations sensibles. Dans certains modes de réalisation, le système reçoit un modèle biométrique en provenance d'un dispositif utilisateur qui est chiffré à l'aide d'une clé publique associée au système. Le modèle biométrique chiffré est ensuite fourni à une seconde entité conjointement avec un identifiant biométrique. Lors de la réception d'une demande d'achèvement d'une transaction qui comprend l'identifiant biométrique et un second modèle biométrique, la seconde entité peut chiffrer le second modèle biométrique à l'aide de la même clé publique associée au système et effectuer une comparaison entre les deux modèles biométriques chiffrés. Le fichier de données de résultat de correspondance résultant est déjà crypté et peut être fourni au système afin de déterminer une étendue à laquelle les deux modèles biométriques correspondent.
Patent WO-2019023542-A1 (WO)
Title: Methods and systems for optimized visual summarization for sequences of temporal event data
Inventor: XU PANPAN
IPC: G06T1/20
Filed: 2018-07-27
Abstract: A method for generating a graphical depiction of summarized event sequences includes receiving a plurality of event sequences, each event sequence in the plurality of event sequences including a plurality of events, and generating a plurality of clusters using a minimum description length (MDL) optimization process. Each cluster in the plurality of clusters including a set of at least two event sequences in the plurality of event sequences that maps to a pattern in each cluster. The pattern in each cluster further includes a plurality of events included in at least one event sequence in the set of at least two event sequences in the cluster. The method includes generating a graphical depiction of a first cluster in the plurality of clusters, the graphical depiction including a graphical depiction of a first plurality of events in the pattern of the first cluster.
Patent WO-2019028198-A1 (WO)
Title: Amidoamine synthesis, methods to track the reaction process
Inventor: KHRAMOV DIMITRI M
IPC: C09K8/02
Filed: 2018-08-02
Abstract: Methods may include quantifying the concentration of residual free amine and/or free carboxylic acid in a product mixture prepared from a reaction of a multireactive species and a fatty reagent; verifying that the concentration for the free amine and/or free acid in the product mixture is within an acceptable threshold for a given application; and combining the product mixture with one or more wellbore fluid components to generate the wellbore fluid. In another aspect, methods may include including reacting the multireactive species and a fatty reactant to generate a product mixture; quantifying the concentration of residual free amine and/or free carboxylic acid in the product mixture; verifying that the concentration for the free amine and/or free acid in the product mixture is within an acceptable threshold for a given application; and collecting the product mixture.
Patent WO-2019036472-A1 (WO)
Title: Corticotropin releasing factor receptor antagonists
Inventor: HOWERTON ALEXIS
IPC: C07D471/04
Filed: 2018-08-14
Abstract: The present invention provides novel pharmaceutical compositions comprising 3-(4-Chloro-2-(morpholin-4-yl)thiazol-5-yl)-7-(1-ethylpropyl)-2,5-dimethylpyrazolo(1,5- a)pyrimidine and methods of using the same for the treatment of Congenital adrenal hyperplasia (CAH).
Patent WO-2020040784-A1 (WO)
Title: Printing device functionality based on consumption and payment
Inventor: SCHALK WESLEY
IPC: G06Q10/10
Filed: 2018-08-24
Abstract: Examples for determining printing device functionality based on consumption and payment are described herein. In some examples, signals indicative of an amount of utilized print consumable by a printing device and signals indicative of payment for the amount of utilized print consumable are received at a computing device. Signals to cause the printing device to alter a functionality based on the signals indicative of an amount of utilized print consumable and the signals indicative of payment for the amount of utilized print consumable are transmitted by the computing device.
Patent WO-2019050733-A1 (WO)
Title: Medical device with tip member
Inventor: CALOMENI MICHAEL P
IPC: A61M25/00
Filed: 2018-08-29
Abstract: Medical devices and methods for making and using medical devices are disclosed. An example system medical device delivery system includes an outer shaft having a proximal end region, a distal end region and a lumen extending therein. The delivery system also includes an inner shaft having a proximal end region, a distal end region and a lumen extending therein, wherein the inner shaft extends within at least a portion of the lumen of the outer shaft. The delivery system also includes a tip member disposed the along the distal end region of the outer shaft, the tip member including a proximal end region and a distal end region; wherein the outer shaft and the inner shaft are configured to position an implantable medical device therebetween and wherein the tip member includes an annular groove positioned adjacent the proximal end region of the tip member.
Patent WO-2019067831-A1 (WO)
Title: Multi-objective generators in deep learning
Inventor: BAKER JAMES
IPC: G06N5/04
Filed: 2018-09-28
Abstract: Machine-learning data generators use an additional objective to avoid generating data that is too similar to any previously known data example. This prevents plagiarism or simple copying of existing data examples, enhancing the ability of a generator to usefully generate novel data. A formulation of generative adversarial network (GAN) learning as the mixed strategy minimax solution of a zero-sum game solves the convergence and stability problem of GANs learning, without suffering mode collapse.
Patent WO-2019099214-A1 (WO)
Title: Routage de déploiement de clients par analytique
Inventor: MOORE TIMOTHY JAY
IPC: G06F11/00
Filed: 2018-11-02
Abstract: Selon certains modes de réalisation, la présente invention concerne le déploiement de mises à jour auprès de multiples clients. Un dispositif peut fournir, à chaque client d'une première pluralité de clients, une mise à jour de logiciel à exécuter au niveau du client. Suite à la fourniture de la mise à jour de logiciel, le dispositif peut transmettre à chaque client de la première pluralité de clients une demande de vérification d'un état du client. Le dispositif peut recevoir, d'au moins un client de la première pluralité de clients, une réponse à la demande indiquant la santé opérationnelle du client suite à la fourniture de la mise à jour de logiciel au client. Le dispositif détermine une statistique de santé opérationnelle de la première pluralité de clients suite à la fourniture de la mise à jour de logiciel à la première pluralité de clients et fournit, à chaque client d'une seconde pluralité de clients, la mise à jour de logiciel devant être exécutée au niveau de chaque client après avoir déterminé que la statistique de santé opérationnelle satisfait un seuil prédéfini.
Patent WO-2019099248-A1 (WO)
Title: Cokéfaction fluidisée avec production accrue de liquides
Inventor: LE TIEN
IPC: C10J3/84
Filed: 2018-11-07
Abstract: L'invention concerne des systèmes et des procédés d'intégration d'un processus de cokéfaction fluidisée, facultativement un processus de gazéification de coke, et des processus de production de produits liquides supplémentaires à partir du processus de cokéfaction et/ou de gazéification. Selon certains aspects, les processus intégrés peuvent permettre la conversion d'oléfines générées pendant un processus de cokéfaction fluidisée pour former des produits liquides supplémentaires. En outre ou en variante, selon certains aspects, les processus intégrés peuvent permettre la séparation de gaz de synthèse du gaz de combustion/gaz combustible généré par un gazéifieur intégré à un processus de cokéfaction fluidisé. Ce gaz de synthèse peut ensuite être utilisé pour former du méthanol, qui peut ensuite être converti dans un processus de conversion de méthanol pour former des produits plus lourds. Dans ces aspects, des oléfines générées pendant le processus de cokéfaction fluidisée peuvent être ajoutées au processus de conversion de méthanol pour améliorer le rendement. De plus, selon divers aspects, le dégagement gazeux provenant du processus de conversion intégré peut être utilisé en tant qu'alimentation en paraffine supplémentaire qui peut être recyclée vers l'un des conduits d'intégration de chaleur dans l'unité de cokéfaction fluidisée pour une génération supplémentaire d'oléfines. Ceci peut permettre une augmentation supplémentaire de rendements de liquide à l'aide d'une source de carbone (paraffines en C4) qui est classiquement considérée en tant que produit à faible valeur provenant de la cokéfaction.
Patent WO-2020096597-A1 (WO)
Inventor: FRANKLIN CHRISTOPHER
IPC: G06Q30/02
Filed: 2018-11-08
Abstract: Systems and methods are described for augmenting visual content with a sponsored object instead of a selected object. An illustrative method receives an input selecting an object for augmenting visual content, determines whether a property of the selected object matches a property of a sponsored object included in a database of sponsored objects, and in response to determining that the property of the selected object matches the property of the sponsored object, augments the visual content with the sponsored object.
Patent WO-2019099598-A1 (WO)
Title: Implant rachidien
Inventor: DEWEY JONATHAN M
IPC: A61F2/30
Filed: 2018-11-15
Abstract: L'invention concerne un implant rachidien destiné à être inséré dans un espace intervertébral entre un corps vertébral supérieur et un corps vertébral inférieur. L'implant rachidien comprend une première partie de plaque d'extrémité supérieure et une seconde partie de plaque d'extrémité inférieure s'étendant chacune à partir d'un emplacement au moins adjacent à une extrémité proximale jusqu'à une extrémité distale de l'implant rachidien. L'implant rachidien est conçu pour faciliter son insertion dans l'espace intervertébral et empêcher son retrait de l'espace intervertébral. A cet effet, l'extrémité avant de l'implant rachidien peut être conçue pour faciliter l'insertion dans l'espace intervertébral, et une surface supérieure et une surface inférieure de la première partie de plaque d'extrémité supérieure et de la seconde partie de plaque d'extrémité inférieure, respectivement, peuvent être pourvues de dépressions ou d'alvéoles formant des arêtes et des points entre celles-ci pour empêcher le retrait de l'espace intervertébral.
Patent WO-2020131011-A1 (WO)
Title: System and method for recommending a transaction to replace a device based upon total cost of ownership
Inventor: DIAZ LUIS J
IPC: G06Q30/02
Filed: 2018-12-17
Abstract: A method and system for recommending a transaction to replace a target device by calculating a total cost of ownership based upon actual device usage data. Based, at least in part, on the TCO for the target device, a recommendation is provided to replace the target device with a replacement device that has a lower TCO than the target device, or a TCO difference compared to the TCO of the target device that is within a predefined range.
Patent WO-2019133987-A1 (WO)
Title: Structure composite résiliente e
Inventor: CRON STEVEN M
IPC: B60C7/18
Filed: 2018-12-31
Abstract: L'invention concerne un rayon (100) pour un pneu qui fixe une bande de roulement externe à un moyeu, le rayon (100) comprenant des premier et deuxième éléments de rayon (142, 144) qui possèdent des renforts d'élément de rayon, les éléments de rayon (142, 144) étant reliés par un corps d'assemblage (130) constitué d'un élastomère reliant le premier élément de rayon (142) au deuxième élément de rayon (144) et une membrane de renforcement (132) qui s'étend depuis le premier élément de rayon (142) vers le deuxième élément de rayon (144) et ayant une première extrémité (172) et une deuxième extrémité (170) et une portion centrale (174), la première extrémité (172) étant plus proche des premiers renforts d'élément de rayon que la portion centrale (174) et la deuxième extrémité (170) étant plus proche du deuxième renfort d'élément de rayon que la portion centrale (174) de la membrane de renforcement (132) de rayon.
Patent WO-2019143689-A1 (WO)
Title: Systems and methods for robotic infection treatment of a prosthesis
Inventor: Krebs Viktor
IPC: A61B34/30
Filed: 2019-01-16
Abstract: A method for debriding an infected implant area using a robotic-assisted surgery system. The method includes determining, by a processing circuit associated with a computer, an area to be debrided, the debridement area including at least a surface of an implant or patient tissue, and generating, by the processing circuit, a plan for debriding the debridement area. The method further includes controlling a debridement tool, by the robotic-assisted surgery system, while the debridement tool is used to carry out the debridement plan, and monitoring the debridement by the processing circuit.
Patent WO-2019144111-A1 (WO)
Title: Pressure regulator
Inventor: FOWLER AMOS
IPC: G05D16/06
Filed: 2019-01-22
Abstract: A pressure regulator for controlling flow of a fluid therethrough is provided. An upper housing member and a primary diaphragm define an upper chamber and a lower housing member and the primary diaphragm define a lower chamber. The pressure regulator further includes: a valve assembly provided within the upper chamber for controlling the flow of the fluid from an inlet body into the upper chamber; a secondary diaphragm provided within the lower chamber and defining a secondary diaphragm driving chamber; and a passageway connecting the inlet body and the secondary diaphragm driving chamber. During operation, the secondary diaphragm driving chamber is filled with the fluid at the inlet pressure, thereby subjecting the secondary diaphragm to the inlet pressure and generating the force for actuating the valve's disengagement from the inlet body. The pressure regulator functions to maintain the outlet pressure at a value that is a predetermined fraction of the inlet pressure.
Patent WO-2019147590-A1 (WO)
Title: Bioaerosol particle detector
Inventor: SAASKI ELRIC
IPC: G01N15/02
Filed: 2019-01-22
Abstract: A particle detector (10) that includes a housing (12) defining a chamber (14), and an air stream injector (16), producing an airstream with entrained particles (20), in the chamber. A light source (22) produces a light beam (24) that intersects with and is wider than the air stream. A light detection assembly (40) detects light generated by scattering of the light beam, by particles in the air stream. A digitizer (38) produces a sequence of scattering digital values, each representing light detected per a first unit of time duration. Additionally, a summing assembly (39) produces a sequence of summed scattering digital values (41), each equaling a sum of a sequential set of n of the digital values, and wherein successive summed digital values are offset by a the first unit of time duration and overlap by n-1 of the first units of time duration with a nearest neighbor. Finally, a detection assembly (42) processes the summed scattering digital values to detect particles.
Patent WO-2019152343-A1 (WO)
Title: Methods of desensitizing against infusion associated reactions in lysosomal acid lipase deficiency (lal-d) patients treated with exogenous lysosomal acid lipase (lal
Inventor: FRIEDMAN MARK
IPC: A61K9/00
Filed: 2019-01-29
Abstract: The disclosure features methods for safely and effectively administering exogenous LAL (e.g., sebelipase alfa) to pediatric LAL-D patients, as well as methods to prevent and ameliorate infusion reactions in LAL-D pediatric patients receiving exogenous LAL. In particular, disclosed herein are specific dosages and regimens for administering exogenous LAL to a pediatric patient having LAL-D, such dosages and regimens being designed to increase a patient's tolerance of the therapeutic, decrease the likelihood of (e.g., desensitize against) an infusion-related reaction, and maximize the amount of dose that may be administered to the patient safely, so as to safely achieve maximum therapeutic benefits.
Patent WO-2019152747-A1 (WO)
Title: Methods and reagents for assessing the presence or absence of replication competent virus
Inventor: BERRY RUTH
IPC: C12Q1/6851
Filed: 2019-01-31
Abstract: Provided are methods of detecting replication competent virus, e.g., replication competent retrovirus such as gammaretrovirus or lentivirus, in a sample containing a cell transduced with a viral vector particle encoding a recombinant and/or heterologous molecule, e.g., heterologous gene product. The methods may include assessing transcription of one or more target genes, such as viral genes, that are expressed in a retrovirus but not expressed in the viral vector particle. Replication competent retrovirus may be determined to be present if the levels of RNA of the one or more target genes is higher than a reference value, which can be measured directly or indirectly, including from a positive control sample containing RNA from the respective target gene at a known level and/or at or above the limit of detection of the assay.
Patent WO-2019203975-A1 (WO)
Title: Heated ceramic faceplate
Inventor: ROCHA-ALVAREZ JUAN CARLOS
IPC: H01L21/67
Filed: 2019-03-19
Abstract: An apparatus for distributing a gas within a process chamber is disclosed. The apparatus has a body formed from a distribution portion surrounded by a coupling portion. A heater is disposed within the distribution portion to heat the body to an elevated temperature. A bridge extends between the coupling portion and the distribution portion. The bridge limits heat transfer between the distribution portion and the coupling portion.
Patent WO-2019195339-A1 (WO)
Inventor: SANTIAGO CORD
IPC: F41H1/04
Filed: 2019-04-02
Abstract: L'invention concerne un casque de protection pouvant comprendre un casque de protection souple qui comprend une pluralité de zones d'impact qui pourraient être adaptées à une activité spécifique, un sport, une position de joueur et/ou le comportement individuel d'un joueur spécifique. Le casque de protection comprenant une pluralité de tampons d'atténuation d'impact accouplés à un revêtement souple peut facilement se conformer à une tête de porteur. Les différents modes de réalisation comprennent des éléments pour fournir un casque de protection matelassé souple ou semi-souple, léger et adapté pour réduire le risque de traumatisme crânien en raison de la configuration rembourrée multicouche.
Patent WO-2019195690-A1 (WO)
Title: Mechanisms for service layer resource ranking and enhanced resource discovery
Inventor: LY QUANG
IPC: G06F16/951
Filed: 2019-04-05
Abstract: A ranking service implemented at a service layer may be configured to provide mechanisms for ranking resources through service layer contexts called ranking events. The ranking service may enable the service layer to augment internally generated rankings, provide resource owners the ability to specify the targeted audience for their resources, and provide the ability for users to specify indications of ranking types that may be available to customize resource discovery results.
Patent WO-2019210140-A1 (WO)
Title: Pressure sensitive needle positioning devices, release mechanisms, and methods
Inventor: RITCHIE ALEXANDRIA
IPC: A61M5/32
Filed: 2019-04-26
Abstract: A device for facilitating positioning of a needle during a medical procedure may include a needle receiver configured for removable/reversible attachment of a proximal end of a needle; a stop set back from a distal end of the needle receiver and against which a needle received by the needle receiver abuts; and a trigger configured to move the needle receiver relative to the stop when activated by a user such that the stop forces detachment between the needle receiver and the needle. The device may monitor the pressure at the distal end of the needle as the needle is advanced and provide indication to a user when a predetermined pressure or pressure differential is reached.