baber/WOPTO huggingface dataset:
Patent EC-SP056082-A (EC)
Title: Terapia para enfermedad autoinmune en un paciente con una respuesta inadecuada a un inhibidor tnf-alfa
Inventor: BENYUNES MARK
IPC: C07K16/28
Filed: 2005-10-07
Abstract: La presente solicitud describe la terapia con antagonistas que se unen a los marcadores de superficie de célula B, tal como CD20. En particular, la solicitud describe el uso de tales antagonistas para tratar la enfermedad autoinmune en un mamífero que experimenta una respuesta inadecuada a un inhibidor TNFa.
Patent EC-SP066713-A (EC)
Title: Forma de dosis solida
Inventor: ALEX RAINER
IPC: A61J3/00
Filed: 2006-07-20
Abstract: Una forma de dosis sólida (1) comprendiendo un patrón magnético predefinido (2), representando información. La forma de dosis (1) puede ser una forma oral de dosis tal como un comprimido o una cápsula, y el patrón magnético (2) puede ser invisible. La información contenida en el patrón magnético (2) puede estar codificada.
Patent EC-SP082712-A (EC)
Title: Procedimiento i para preparar derivados de tiazolidindiona
Inventor: GILES ROBERT GORDON
IPC: C07D417/12
Filed: 2008-07-08
Abstract: Un procedimiento para preparar un compuesto de fórmula (I); una de sus formas tautómeras o una de sus sales farmaceuticamente aceptables, o uno de sus solvatos farmaceuticamente aceptables, en la que:A1 representa un grupo heterociclilo aromático sustituido o no sustituido;R1 representa un átomo de hidrogeno, -un grupo alquilo, un grupo acilo, un grupo aralquilo, en el que el resto arilo puede estar sustituido o no sustituido, o un grupo arilo sustituido o no sustituido; A2 representa un anillo de benceno que tiene en total hasta cinco sustituyentes; y n representa un numero entero en el intervalo de 2 a 6, comprendiendo dicho procedimiento reducir cataliticamente un compuesto de fórmula (II): en la que A1, R1, A2 y n son como se han definido con relación a la fórmula (I), caracterizado porque la reacción de reducción se realiza usando una presión de hidrógeno superior a 1,4 Kg./cm2 (20 psi); y a continuación, si se requiere, formar una sal farmaceuticamente aceptable y/o un solvato farmaceuticamente aceptable del compuesto de formula (I).
Patent EC-SP951484-A (EC)
Title: Radiotelefono con multiples y simultaneas identidades de numeros de telefono
Inventor: COMER EDWARD IRBY
IPC: H04M3/04
Filed: 1995-07-20
Abstract: El invento, en resumen, consiste en un sistema novedoso en el cual un aparato de radioteléfono contiene un transceptor que monitorea un canal de control de señales de búsqueda y un controlador que controlado automáticamente por un transceptor genera una señal de reconocimiento en respuesta de recibo de una señal de búsqueda que lleva una identidad de numero de teléfono la cual es una pluralidad de identificaciones de números telefónicos predeterminados.
Patent EC-SP993077-A (EC)
Title: Productos derivados de las sulfonamidas
Inventor: BENDER DAVID MICHAEL
IPC: C07C311/03
Filed: 1999-07-28
Abstract: La presente invención se refiere a la potenciación de la función de glutamato usando ciertos derivados de sulfonamida. También se refiere a nuevos derivados de sulfonamida, a procedimientos para su preparación y a composiciones farmacéuticas que los contienen.
Patent FI-20010041-A (FI)
Inventor: SOEDERLUND HANS
IPC: C12Q1/6816
Filed: 2001-01-10
Abstract: The invention is related to a method and test kits for quantitative determination of polynucleotide amounts present in a sample. The test kit comprises organized pools with polynucleotide probes having distinct sizes and optionally provided with tracer tags or primer tags. The probes are allowed to hybridize with affinity tagged analyte polynucleotides from the sample. The result is hybrids, which can be recovered on a separation aiding tool provided with the pair of the affinity tag. After the quantitative release of the probes, the probes are either directly recorded, or if primer tagged, they are amplified and optionally provided with a tracer tag before recording. The invention provides a sensitive and quantitative determination of the amount polynucleotides present in a cell or tissue sample and allows a quantitative assessment of variations in the amounts of polynucleotides as a response to inherent changes or due to external stimuli.
Patent FI-20040401-A (FI)
Inventor: VENKATACHARI SRIKANTH
IPC: F04D15/02
Filed: 2004-03-16
Abstract: A method and an arrangement for controlling a pump station includes measurement of the surface level of a liquid (465) by means of a sensor (452) and controlling the electric drive (401, 420, 430) of the pump (440) to a predetermined speed of rotation when a specific surface level value has been reached. This predetermined rotation speed value is preferably the rotation speed at which the ratio of the flow rate to the consumed power, i.e. the efficiency, is optimal. The measurement of the surface level and the related data processing for control of the pump are performed in a frequency converter (420) in conjunction with the control.
Patent GB-1050853-A (GB)
IPC: B02C4/22
Abstract: 1,050,853. Roller-and-bar mills. J. M. A. BRIZON. May 27, 1964 [May 31, 1963], No. 21858/64. Heading B2A. In a roller-and-bar mill in which the bar is pressed against the roller, e.g. by means of fluid-pressure operated jacks, the bar having two lips separated by a groove which is closed at its extremities, the thickness of the two lips combined is at most equal to the width of the groove and discharge means are provided to limit and control the back pressure of the material which fills the groove. As shown in Fig. 1, material is discharged from the groove of bar 4f and returned to hopper 2 by means of a conduit 11f 12f in which is disposed a gear pump 10f driven from roller 1. The pump may be driven independently. In a modification. Fig. 3, groove 9 communicates through an orifice 25 with a bore 26 the position of which is controlled by a rod 26a coupled to a screw 26b having a micrometric thread and operable by a knob 29 carrying graduations opposite a reference mark carried by a member 30. In a further modification, a rod, similar to rod 26a is coupled to an elastic diaphragm which is fixed to a screw, similar to screw 26b, through the intermediary of an elastic member.
Patent GB-1054653-A (GB)
IPC: C08G18/48
Abstract: 1,054,653. Polyethers. ISOCYANATE PRODUCTS Inc. Jan. 10, 1964 [Jan. 10, 1963], No. 1281/64. Addition to 947.483. Heading C2C. [Also in Division C3] Non-linear polyethers comprise the reaction product of an alkylene oxide with a liquid mixture of a sugar and a polyhydric alcohol, the polyether having a molecular weight of 2000 to 7500. The alcohol generally constitutes 20 to 80% of the solvent/sugar system. The specified sugars are arabinose, glucose, galactose, fructose, lactose, glycerose, xylose, sucrose and dextrose. The specified solvents are water, ethylene glycol, glycerol, hexanetriol, pentaerythritol, i-erythritol, adonitol, oxylitol, arabitol, dulcitol, aditol, mannitol and sorbitol. Specified alkylene oxides are ethylene, propylene and tri-, tetra-, and pentamethylene oxides; oxides containing aryl, cycloaliphatic, chloroformate and butene groups may also be used. The examples describe the preparation of polypropoxylated sorbitol/sucrose.
Patent GB-1227118-A (GB)
IPC: B23Q16/10
Filed: 1969-05-05
Abstract: 1,227,118. Tool post turrets. P. TRAUTWEIN. 5 May, 1969 [15 May, 1968], No. 22840/69. Heading B3T. An indexable tool holding assembly comprises a tool turret carrier 1 which is rotatably mounted on a stud 2 secured to a base-plate 3 and which is clampable thereto in selected positions determined by a spring plunger 13, by rotation of a thrust-ring 29 on the stud 2 which by successive engagement between successive inclined surfaces 33, 34, on the ring 29 and a thrust sleeve 15 respectively displaces the carrier 1 against spring 28 axially of the stud to engage opposed axially extending teeth on rings 11 and 8, respectively, and effects self-locking between the thrust ring and thrust sleeve to clamp the carrier in its indexed position. The clockwise rotation of the ring 29 by the handle 35 effects the clamping action, the carrier being retained in its selected position by the plunger 13 engaging in a recess 14 in the ring 8 until the axial teeth on the rings 8 and 11 engage to prevent rotary movement of the carrier. Anticlockwise rotation of the handle releases the nut 31 and the ring 29 by relative movement between the cam surfaces of the ring and thrust sleeve, the carrier being urged upward by the spring 28 thereby disengaging the teeth on rings 8 and 11 to permit rotation of the carrier about the stud to the next position determined by a further recess 14 in which the spring plunger 13 in the carrier engages.
Patent GB-1229556-A (GB)
IPC: D01G15/08
Filed: 1969-02-28
Abstract: 1,229,556. Carding machines. T.M.M. (RESEARCH) Ltd. 12 Feb., 1970 [28 Feb., 1969], No. 10776/69. Heading DIN. A carding machine comprises two sets of spaced flats 6, 12, and a worker roll and a stripper roll 9, 10 positioned between and spaced from these flats. The flats may rotate in opposite directions. The worker and stripper rolls may rotate in opposite directions.
Patent GB-1233753-A (GB)
IPC: B21D53/08
Filed: 1968-12-18
Abstract: 1,233,753. Bending and corrugating. OLIN CORP. 18 Dec., 1968 [1 March, 1968], No. 60194/68. Headings B3A and B3E. Apparatus for bending strip comprises a fixed base 10, Fig. 1, a spindle 30 having at least one groove and which is mounted on the fixed base, a movable base 20 pivoted at the spindle and on which a roller 90 is mounted, means 120 for co-operating with the roller for deforming the strip S, means for holding the strip in operative engagement with the spindle groove and means for rotating the movable plate 20 around the spindle 30. In operation, a piece of strip S which contains stop-weld at appropriate places is fed through clamping block 100 and is placed upon adjustable screws 150. The height of the screws 150 is adjusted so that the areas in the strip corresponding to the desired passageways which contain stop-weld are in alignment with pins 126 or 126a, Fig. 5, on the follower block 120 and the grooves 41-44 on the die spindle. The strip is clamped in the clamping block 100 by tightening bolt 104 at a part whereby the bend will occur at the die spindle at the desired length of strip. One side of the strip contacts die spindle 40. The follower block 120 and pins are then brought into contact with the other side of the strip. Also at this point a retainer strap 130 is engaged upon the die spindle nut 46. The locking tee 140 is inserted into opening 132 in the retainer strap and into opening 82 in the guide top. The adjusting bolt 51 is rotated to urge the wiper block 90 into firm engagemente with the follower block. At this point the entire movable assembly is rotated with respect to the fixed plate 10 around the die spindle 40. Fig. 8 shows a strip processing sequence where the previously described bending takes place at the bending station 400 after which fin material 411, end plates 413 and headers 414 are assembled at the assembly station 410. The fin material and/or the strip will contain a coating of brazing material so that when the strip-fin nuts 412 are introduced into the furnace 420 the fin material is solidly brazed to the strip. The strip is then moved on to the inflation station 430, where at one end of the strip an inflation needle is introduced into the pattern of stopweld material and clamped by means of hydraulic line 432. Fluid pressure by means of air line 431 inflates the passageway after which the inflated articles are checked for leaks in a water tank 440.
Patent GB-1237958-A (GB)
IPC: A63B49/00
Filed: 1969-01-23
Abstract: 1,237,958. Tennis &c. rackets. HELSING- BORGS GUMMIFABRIKS TRETORN A.B. 23 Jan., 1969 [23 Jan., 1968; 10 June, 1968], No. 3834/69. Heading A6D. A racket of the type in which the frame to which the stringing is attached is detachably supported by a main frame comprises a first member or detachable frame or bow A on which the stringing is mounted and a second member or main frame B (Fig. 1). The first member has a stringing frame 1 made of an outwardly facing U-channel, formed in a slightly oval closed configuration and supporting the stringing of the racket at its inner periphery. In the U-channel of the frame 1 is held the second racket member B which comprises a main frame 3 of twin metal tubes 11, 12 (Fig. 2) bonded together and fashioned in a central curved portion 6 which encircles and nests in most of the periphery of the outer frame 1, and two shanks 4, 5 extending from the portion 6 to define the shaft of the racket. The ends of the shanks enter the socket 16 of handle 9. A curved crosspiece 7 is disposed between the shanks 4 and 5 and at their juncture with the curved portion 6 of the main frame 3 nests in the U channel of the string- ing frame 1. A second crosspiece 8 joins together the shanks 4 and 5 and serves to clamp them together and draw the main frame 3 tightly into the U channel of the stringing frame 1. The latter is provided with a plurality of apertures 50 (Fig. 2) through which the strings 51 are laced. The crosspiece 8 comprises two abutting tubular sections 17 and 18 (Fig. 4) which are attached at their ends to sleeves 19 and 20 brazed to the shanks 4 and 5 and are brought into the abutting position by means of a coupling nut 21 which engages a flange 23 on the end of the tubular section 17 and rotates on the threaded nipple 22 of the tubular section 18. A locking pin 25 having caps 26 and 27 at its ends and passing through the apertures 53, 54 of the sections 17, 18, prevents the sections 17 and 18 from being separated more than a distance sufficient to enable the frame 1 to be detached from the frame 3. The handle 9 is formed of two symmetrical segments 55, 56 joined by screw 57 (Fig. 6). A socket 16 for receiving the shanks 4, 5 is provided in each handle section (Figs. 5 and 6) and the ends of the shanks are detachably held in position by a coupling means 10 (Fig. 6). The means 10 comprises a washer 31 mounted on a pivot pin 29 (Fig. 5) which extends through the bottom end wall 28 of the handle. Upon rotation of the pin 29 the washer 31 engages grooves 32 and 33 in the shanks 4 and 5 at 180‹ positions and thereby detachably engages the shanks in the handle. An alternative device for locking the handle 9 to the shanks 4 and 5 and clamping means for clamping the handle to the shaft are described.
Patent GB-1239277-A (GB)
IPC: B60R1/06
Filed: 1968-10-21
Abstract: 1,239,277. Rear view mirrors. SACHSENRING AUTOMOBILWERKE ZWICKAU VEB. 21 Oct., 1968, No. 49871/68. Heading B7J. [Also in Divisions E1-E2] A rear-view mirror assembly is attached to a vehicle by a substantially U-shaped clamp 5 which, held in position on a door frame 1 of the vehicle by clamping screws 4 in the inboard arm of the clamp 5, partially embraces the door frame 1, the heads of the screws 4 when the door is closed being directed towards the interior of the vehicle and covered by a dash column 3, and which clamp 5 has a semicylindrical recess 8 which together with a semicylindrical recess 7 in a bearing plate 6 forms a cylindrical bore 9 to receive one end of an arm 10 of the mirror 11 which arm 10 has a circumferential guide groove 12 engageable by a pin 13 in bearing plate 6. A pressure plate 14 is inserted between the door frame 1 and the clamping screws 4.
Patent GB-1239468-A (GB)
IPC: C01B31/30
Filed: 1968-11-15
Abstract: 1,239,468. Refractory metal carbides. UGINECARBONE. 15 Nov., 1968 [16 Nov., 1967], No. 54374/68. Heading C1A. Refractory metal carbides in fine powder form are prepared by suspending carbon in an aqueous solution of pH #7 of at least one salt, preferably the chloride, of at least one of the metals, increasing the pH of the solution by the addition of, for example, concentrated ammonia in order to completely precipitate the metal hydroxides, washing and roasting the resultant gel so that it contains only oxides and carbon, and reacting these together by heating at a temperature of from 1600‹ to 2000‹ C. under vacuum or under a reducing atmosphere. Specified metals are Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, U, Th and the lanthanides. The carbon is preferably added in the form of lampblack or acetylene black and the final products advantageously have a free carbon content of 1% maximum, a mean particle size of less than 2 Á, and a specific BET surface area of between 1 and 3 m.<SP>2</SP>/g.
Patent GB-1252405-A (GB)
IPC: A44B19/12
Filed: 1970-02-02
Abstract: 1,252,405. Sliding clasp fasteners. OPTIHOLDING A.G. 2 Feb., 1970 [12 March, 1969], No. 4807/70. Heading E2S. A series of interlocking elements for a sliding clasp fastener, of the distorted helical type, having the axis of the locking element normal to the plane of the fastener is characterized in that the arms 2 of the interlocking elements in the region of the interlocking heads have faces 6 stamped onto them. The faces may be formed by a V-shaped stamp using hot or cold pressing. The faces 6 define a rhombic housing in which the head of the opposite interlocking element is held.
Patent GB-1252923-A (GB)
IPC: B23K20/12
Filed: 1968-02-05
Abstract: 1,252,923. Welding by pressure. STEELWELD Ltd. 3 Feb., 1969 [5 Feb., 1968], No. 5666/68. Heading B3R. In friction welding apparatus of the type including a pair of chucks, at least one of which is rotatable, arranged for relative axial displacement, one chuck is movable by a ram or rams and the other is secured to a shaft supported in bearings permitting limited axial movement and in operation is supported against the axial thrust of the ram or rams by an hydrostatic thrust bearing. An axially movable, non- rotary chuck 10 is supported on the piston-rod of a piston 12 of an hydraulic ram 13 which is supplied with fluid from the same source as that delivered to the bearing arrangement 15 supporting a rotary chuck 11. The rotary shaft 14 is provided with a collar 26 whose rear face 27 extends close to a recess or recesses 25 in a diaphragm 19 secured in housing 16, the shaft being supported in journal bearings 17 permitting limited axial movement thereof. Hydraulic fluid supplied to the recess or recesses 25 leaks between the opposed faces of the diaphragm 19 and collar 26 to constitute a hydrostatic thrust bearing supporting the chuck 11 against the axial thrust of the ram 13 transmitted to it through the workpieces.
Patent GB-1259478-A (GB)
IPC: F16J9/00
Filed: 1969-10-14
Abstract: 1,259,478. Piston rings. LINDE A.G. 14 Oct., 1969 [14 Oct., 1968], No. 50288/69. Heading F2T. A piston comprises a piston-rod 18 guided by a dry anti-friction material, e.g. P.T.F.E., bearing 17 and a head 1 having a number of guide rings 8 biased outwardly in grooves 5, means being provided for preventing further outward movement when a predetermined amount of wear of the rings has occurred. The rings are biased by gas pressure and springs 10 and may be made of P.T.F.E. The means preventing further outward movement may comprise shoulders 9 on the ring gengagings houlders 12 in the groove, Fig. 1, or the shoulders may be angled and the ring biased by a corrugated metal spring (28), Fig. 2 (not shown), a radial pressure balance groove (29) being provided. The shoulders on the ring may be in the form of a swaged on annular metal housing, Figs. 3, 4 (not shown), and the ring may have labyrinth grooves (53) at its working face, Fig. 4 (not shown). The shoulders may be replaced by axially extending pins which may have end pegs (61), Fig. 5 (not shown), and be insertable through radial channels (63) in the piston or the rings may have common pins, the pins being surrounded by either bushes (70) in the body of the ring, Fig. 6 (not shown), or a metal housing 7, 9 may be attached to the ring, Fig. 7. One ring 81 includes a sheet metal ring 85. Passages may be provided for the admission of cooling medium to the bearing 17.
Patent GB-1264073-A (GB)
IPC: C22B9/20
Filed: 1970-05-07
Abstract: 1,264,073. Casting processes. CARPENTER TECHNOLOGY CORP. 7 May, 1970 [9 June, 1969], No. 22203/70. Heading B3F. [Also in Division H5] In a method of casting by melting a consumable electrode 10, a diffuse electric discharge 12 is formed between the electrode 10 and a counter electrode 21 spaced from the pool 13 of molten metal in the mould 20 so that no more than a minor portion of the discharge current passes through the pool 13. Since magnetic fields can disrupt the diffuse discharge it is necessary to maintain any stray magnetic fields in the mould below the level at which disruption occurs. This may be achieved by careful location of the current conductors or by cancelling out such fields by inducing equal and opposite fields by means of an external electromagnetic coil. The process is preferably carried out at a pressure of less than 10 mm. Hg using an atmosphere of argon. In an embodiment. the pool of molten metal is covered by a layer of flux and the walls of the mould constitute the counter electrode. The process is started off in a conventional way by striking an arc between the electrode and some starting material in the bottom of the mould. The distance between the electrode and the pool of molten metal is then increased until all the discharge is in the form of a diffuse discharge between the electrode and counter electrode.
Patent GB-1264725-A (GB)
IPC: A61B1/233
Filed: 1970-08-12
Abstract: 1,264,725. Otoscope. WELCH ALLYN Inc. 12 Aug., 1970. [7 Oct., 1969], No. 38890/70. Heading ASR. An otoscope comprises a speculum 22 and a hollow head 21, the rear of which is closed by a removable lens 36 having a resilient non- metal frame 37 whereby the frame also acts as a gasket to provide an airtight closure. In use the speculum is sheathed in a detachable hollow tip 30 that is attached by means of a log and slot 31. The head 21 is connected to a handle 16 via a lug 24 and a tubular throat piece 25. The handle contains a lamp 19, batteries, a switch 17 and a rheostat dial 18. A bundle of clad light transmitting fibres 28 pass from the lamp to the end of the speculum at 27. The lens 36 and frame 37 slide within the opening 32 of the head. The frame comprises a low friction elastomer and effects an airtight seal. If the lens and frame are removed surgical instruments may be inserted into the auditory canal. In one embodiment of the invention an inflation bulb (40) and tube (41) may be attached to inlet 44 to enable the tinpanum to be activated.
Patent GB-1265048-A (GB)
IPC: B65H31/40
Filed: 1969-09-19
Abstract: 1,265,048. Knocking-up devices. HOBSON DESIGNS Ltd. 12 Aug., 1970 [19 Sept., 1969], No. 46238/69. Heading B8R. A knocking-up device comprises a resiliently mounted inclined table 2 provided with upstanding edge guides 4 and an electric motor 14 provided on its drive-shaft with an eccentric 36 upon which is eccentrically journalled a weight 40. There is no driving connection between the shaft and the table. The motor and table are carried by rubber pillars 16 supported on plate 22 connected to supporting column 26 through ball head 24. The eccentricity of weight 40 is adjustable to provide the most efficient jogging for the type of sheets used.
Patent GB-1266141-A (GB)
IPC: E04B2/84
Filed: 1968-02-26
Abstract: 1,266,141. Moulding concrete. GEORGE WIMPEY & CO. Ltd., and E. V. COLLINS. 10 Feb., 1969 [26 Feb., 1968], No. 9254/68. Heading B5A. [Also in Division E1] Concrete slabs are moulded with facing panels 12 detachably secured thereto by lining at least one side of shuttering 10 and 11 with panels 12, which may have foamed plastic backing 21. Each panel detachably engages clip 13 which may be held against shuttering 10 by a spring device (22, Fig. 2, not shown). Concrete is poured in and when it sets anchors the flanges 18 of the clips. Removal of the shuttering enables the panels 12 to be detached.