baber/WOPTO huggingface dataset:
Patent WO-2020251842-A1 (WO)
Inventor: MCPHERSON BRICE
IPC: H01L25/07
Filed: 2020-06-05
Abstract: A package for power electronics includes a power substrate, a number of power semiconductor die, and a Kelvin connection contact. Each one of the power semiconductor die are on the power substrate and include a first power switching pad, a second power switching pad, a control pad, a semiconductor structure, and a Kelvin connection pad. The semiconductor structure is between the first power switching pad, the second power switching pad, and the control pad, and is configured such that a resistance of a power switching path between the first power switching pad and the second power switching pad is based on a control signal provided at the control pad. The Kelvin connection pad is coupled to the power switching path. The Kelvin connection contact is coupled to the Kelvin connection pad of each one of the power semiconductor die via a Kelvin conductive trace on the power substrate.
Patent WO-2020264355-A1 (WO)
Title: Method and system for computer-aided triage of stroke
Inventor: MANSI CHRISTOPHER
IPC: A61B6/03
Filed: 2020-06-26
Abstract: A system for computer-aided triage includes a router, a remote computing system, and a client application. Additionally or alternatively, the system too can include any number of computing systems, servers, storage, lookup table, memory, and/or any other suitable components. A method for computer-aided triage includes receiving a data packet associated with a patient and taken at a first point of care; checking for a suspected condition associated with the data packet; in an event that the suspected condition is detected, determining a recipient based on the suspected condition; and transmitting information to a device associated with the recipient.
Patent WO-2021016227-A1 (WO)
Title: Synthetic genetic elements for biomanufacture
Inventor: PERRY WILLIAM
IPC: C12N15/86
Filed: 2020-07-21
Abstract: Recombinant constructs, cells and means for improved production of Adeno-Associated Viruses (AAVs) are described. Also described are methods of using the constructs and cells to produce recombinant AAVs.
Patent WO-2021086460-A1 (WO)
Inventor: SPIRES GREGORY
IPC: E02B11/00
Filed: 2020-07-24
Abstract: L'invention concerne des systèmes, des procédés et des appareils de gestion de l'eau de pluie permettant de contenir et de filtrer l'eau de ruissellement. Dans un mode de réalisation, un système de gestion de l'eau de pluie peut comprendre une chambre d'eau de pluie conçue pour être placée sous terre ; une rampe d'extrémité évasée à l'entrée de la chambre d'eau de pluie qui est configurée pour recevoir de l'eau de ruissellement contenant des sédiments et pour distribuer le sédiment sur une largeur de la chambre d'eau de pluie ; et un tissu de filtration situé au-dessous de la chambre d'eau de pluie, le tissu de filtration étant configuré pour capturer des sédiments à partir de l'eau de ruissellement dans la chambre d'eau de pluie pendant que l'eau de ruissellement s'écoule hors de la chambre d'eau de pluie.
Patent WO-2021022097-A1 (WO)
Inventor: BEMENT COURTNEY
IPC: C12N9/04
Filed: 2020-07-30
Abstract: Described are compositions and methods relating to modified yeast that over-expresses Adh5p and harbor a heterologous phosphoketolase pathway. The yeast demonstrates increased ethanol production from glucose compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates.
Patent WO-2021026100-A1 (WO)
Title: Dérivés de pyridine en tant qu'inhibiteurs de kif18a
Inventor: TAMAYO NURIA A
IPC: C07D405/14
Filed: 2020-08-03
Abstract: L'invention concerne des composés amide de formule (I) : tels que définis dans la description, et des intermédiaires synthétiques de ceux-ci, qui sont capables de moduler la protéine KIF18A, ce qui permet d'influencer le processus du cycle cellulaire et de la prolifération cellulaire pour traiter le cancer et les maladies associées au cancer. L'invention concerne également des compositions pharmaceutiques, comprenant les composés, et des méthodes de traitement d'états pathologiques liés à l'activité de KIF18A.
Patent WO-2021030265-A1 (WO)
Inventor: MAURER FRANZ
IPC: B32B27/32
Filed: 2020-08-10
Abstract: Methods and apparatus for producing packaging films are disclosed. The apparatus is configured to cut a piece of polymer film with active agent at a cutting station, transfer the piece of film to a sealing station and then seal the piece of film to a base film that preferably comprises a foil, thereby forming the packaging film.
Patent WO-2021050421-A1 (WO)
Title: Systems and methods for processing images of slides for digital pathology
Inventor: LOCK JASON
IPC: G06T7/00
Filed: 2020-09-08
Abstract: Systems and methods are disclosed for receiving a target electronic image corresponding to a target specimen, the target specimen comprising a tissue sample of a patient, applying a machine learning system to the target electronic image to determine at least one characteristic of the target specimen and/or at least one characteristic of the target electronic image, the machine learning system having been generated by processing a plurality of training images to predict at least one characteristic, the training images comprising images of human tissue and/or images that are algorithmically generated, and outputting the target electronic image identifying an area of interest based on the at least one characteristic of the target specimen and/or the at least one characteristic of the target electronic image.
Patent WO-2021055533-A1 (WO)
Title: System and method for additively manufacturing an ankle foot orthosis
Inventor: SHIH ALBERT
IPC: B29C64/00
Filed: 2020-09-17
Abstract: An additively manufactured ankle-foot orthosis. The ankle-foot orthosis includes an additively manufactured footplate and a calf cuff separate from the additively manufactured footplate. A pre-fabricated strut connects the additively manufactured footplate to the additively manufactured calf cuff and includes thickness and width adapted to define a patient-specific stiffness about an ankle joint of a patient. The stiffness of the pre-fabricated strut is suited to one or more of a gait need or a gait requirement of each patient, and the additively manufactured footplate has a portion with a shape complementary to a shape of a portion of the pre-fabricated strut. So configured, a collective shape and volume of the additively manufactured footplate and the pre-fabricated strut together are adapted to fit inside a shoe of the patient.
Patent WO-2022066156-A1 (WO)
Inventor: PEROZZI BRYAN
IPC: G06F16/25
Filed: 2020-09-24
Abstract: Systems and methods for generating single-node representations in graphs comprised of linked nodes. The present technology enables generation of individual node embeddings on the fly in sublinear time (less than  O ( n ), where  n  is the number of nodes in graph  G ) using only a PPR vector for the node, and random projection to reduce the dimensionality of the node's PPR vector. In one example, the present technology includes a computer-implemented method comprising obtaining a graph having a plurality of nodes from a database, generating a personal pagerank vector for a given node of the plurality of nodes, and producing an embedding vector for the given node by randomly projecting the personal pagerank vector, wherein the embedding vector has lower dimensionality than the personal pagerank vector.
Patent WO-2021067763-A1 (WO)
Inventor: COLE MAURY D
IPC: G09B23/30
Filed: 2020-10-02
Abstract: The present disclosure provides systems and methods for visualizing various effects of consuming (e.g., inhaling) one or more substances, especially on the human brain and lungs.
Patent WO-2021080901-A1 (WO)
Title: Precursor materials for li-ion battery cathode synthesis
Inventor: PULLEN ADRIAN W
IPC: H01M4/36
Filed: 2020-10-19
Abstract: Provided are particles for use as a precursor material for synthesis of Li-ion cathode active material of a lithium-ion cell comprising: a non-lithiated nickel oxide particle of the formula MOx wherein M comprises 80 at% Ni or greater and wherein x is 0.7 to 1.2, M optionally excluding boron in the MOx crystal structure; and a modifier oxide intermixed with, coated on, present within, or combinations thereof the non-lithiated nickel oxide particle, wherein the modifier oxide is associated with the non-lithiated nickel oxide such that a calcination at 500 degrees Celsius for 2 hours results in crystallite growth measured by XRD of 2 nanometers or less. Also provided are processes of forming electrochemically active particles using the precursors nickel oxides.
Patent WO-2021081081-A1 (WO)
Inventor: BRODY JONATHAN R
IPC: A61K31/337
Filed: 2020-10-21
Abstract: L'invention concerne des compositions de sels de pyrvinium appropriées pour une administration orale. Ces compositions se présentent sous la forme de solutions et présentent une biodisponibilité à la fois dans le plasma sanguin et dans le tissu pancréatique. L'invention concerne également des méthodes de traitement, d'amélioration et/ou de prévention du cancer du pancréas, comprenant l'administration par voie orale d'une composition de pamoate de pyrvinium.
Patent WO-2022108598-A1 (WO)
Title: Method and apparatus for predicting drilling fluid viscosity
Inventor: YE XIANGNAN
IPC: E21B21/08
Filed: 2020-11-20
Abstract: A system and method for acquiring and processing single point viscosity measurements in well operations to predict flow curves,  e.g ., for mud flow, for monitoring and predicting viscosity of fluid flow in order to identify abnormal conditions for taking remedial action.
Patent WO-2021108784-A1 (WO)
Title: Systèmes et procédés pour une participation et une rétroaction d'utilisateur améliorées par l'intermédiaire d'une collecte de données dynamique
Inventor: MIAN ALEC
IPC: A61B5/00
Filed: 2020-11-29
Abstract: L'invention divulgue des systèmes et des procédés comprenant la fourniture, à un dispositif client associé à un utilisateur, d'une pluralité d'invites d'entrée conformément à une première résolution temporelle. Des modes de réalisation comprennent la réception, en provenance du dispositif client, de données individuelles comprenant des réponses à la pluralité d'invites d'entrée. Les données individuelles représentent au moins (i) un premier facteur de symptôme de l'utilisateur et (ii) un premier symptôme de l'utilisateur. Des modes de réalisation comprennent la détermination, sur la base au moins en partie, de la réception des données individuelles, d'une première intensité d'une association statistique entre le premier facteur de symptôme et le premier symptôme pour l'utilisateur. Des modes de réalisation comprennent la détermination du fait que la première intensité dépasse une première intensité seuil d'association. Des modes de réalisation comprennent, en réponse à la détermination du fait que la première intensité dépasse la première intensité seuil d'association, la fourniture d'une invite d'entrée affinée au dispositif client qui (i) concerne le premier facteur de symptôme et (ii) réduit la première résolution temporelle à une seconde résolution temporelle.
Patent WO-2021142058-A1 (WO)
Title: Article carrier and blank therefor
Inventor: STEPKOWSKI BARTLOMIEJ
IPC: B65D71/18
Filed: 2021-01-07
Abstract: Aspects of the disclosure relate to a package, an article carrier for packaging a plurality of articles and to a blank for forming the article carrier. The article carrier may package at least one article having a recess. The article carrier comprises a plurality of panels for forming a tubular structure for surrounding at least one article. The article carrier comprises an article retention device for engaging a recess of one of said at least one article. The article retention device may inhibit dislodgement of the article from at least one of opposite open ends of the tubular structure in a setup carrier. The tubular structure defines a tubular axis. The article retention device comprises a flap hingedly connected to a first one of the plurality of panels along a first fold line. The first fold line extends at an acute angle with respect to the tubular axis. The acute angle may be no more than 50 degrees.
Patent WO-2022015365-A1 (WO)
Title: Methods of treating proteinopathies
Inventor: MACALLISTER THOMAS
IPC: A61K31/519
Filed: 2021-01-08
Abstract: The present invention relates to the treatment of conditions associated with a proteinopathy using a therapeutically effect amount of a rho kinase inhibitor. One preferred inhibitor is fasudil and preferred methods involve the daily oral administration of between 20 and 250 mg of fasudil. Proteinopathies preferably treated according to the invention involve aggregates of one or more of the following: amyloid beta, tau, Tar DNA Binding Protein 43 (TDP-43), Fused in sarcoma (FUS), α-synuclein, Huntingtin, Superoxide dismutase 1 (SOD-1), Prion proteins (PrP), mutant forms of Transthyretin, Atrophin 1 (ATN1), the Androgen receptor (AR), Ataxin 1 (ATXN1), Ataxin 2 (ATXN2), Ataxin 3 (ATXN3), Calcium Voltage-Gated Channel Subunit Alpha1 (ACACNA1A), Ataxin 7 (ATXN7), Protein Phosphatase 2 Regulatory Subunit Bbeta (PPP2R2B), and Tata Box Binding Protein (TBP).
Patent WO-2021158801-A1 (WO)
Title: User equipment (ue) capability on band group sharing of same quasi co-location (qcl) parameter
Inventor: RYU JUNG HO
IPC: H04L5/00
Filed: 2021-02-04
Abstract: Aspects of the present disclosure relate to wireless communications, and more particularly, to techniques for signaling user equipment (UE) capability for sharing quasi co-location (QCL) parameter across a group of frequency bands. For example, the UE may report, to a network entity, a capability of the UE to apply a common spatial QCL parameter for at least one group of frequency bands. The UE receives an indication of a change to the common transmission control indicator (TCI) states or spatial relation parameter to be applied across the group of frequency bands. The UE applies the change across the group of frequency bands.
Patent WO-2021173526-A1 (WO)
Inventor: SEN CHANDAN K
IPC: A61K31/7105
Filed: 2021-02-23
Abstract: Compositions and methods are provided for promote wound healing in a subject by administering a miR-1 inhibitor to a wound on subject. In accordance with one embodiment such compositions are used in conjunction with known treatments for use on chronic wounds including in diabetic patients.
Patent WO-2021194712-A1 (WO)
Title: Dispositif de commande de tension de mode commun pour amplificateur push-pull à auto-amplification
Inventor: TERWAL REMCO
IPC: H03F3/217
Filed: 2021-03-04
Abstract: La présente invention concerne selon divers modes de réalisation des systèmes pour amplifier des signaux d'entrée. Dans des modes de réalisation particuliers, un système comprend un dispositif de commande de tension de mode commun configuré pour recevoir un signal d'entrée et délivrer en sortie une paire de signaux ajustés ; un modulateur qui génère une paire de signaux de modulation de largeur d'impulsion (PWM) en réponse aux signaux ajustés ; et un amplificateur push-pull à auto-amplification configuré pour recevoir les signaux PWM et générer une sortie amplifiée, l'amplificateur push-pull à auto-amplification étant configuré pour générer une tension de mode différentiel représentative d'une version amplifiée du signal d'entrée, les signaux audio ajustés générés par le dispositif de commande de tension de mode commun comprenant un gain ajusté de manière dynamique et un décalage de cycle de service qui amène l'amplificateur push-pull à auto-amplification à fonctionner avec une tension de mode commun réduite.
Patent WO-2022191846-A1 (WO)
Title: Gas evaporation and flame extinguishment
Inventor: SCHLUMM DORON
IPC: G03G15/10
Filed: 2021-03-11
Abstract: In an example, a heated air knife and a negative pressure component are controlled to heat a subject gas and direct the subject gas through an evaporation channel at a target gas velocity that is above a flame propagation velocity for the subject gas. The evaporation channel is defined in part by a first surface, a nozzle of the air knife, a mixing zone, and a second surface substantially opposite the first surface.
Patent WO-2021222147-A1 (WO)
Inventor: WANG RUI
IPC: A61K31/7068
Filed: 2021-04-26
Abstract: The invention relates to methods of using modulators of GCN2 and compositions thereof, in the treatment of cancers and other diseases and disorders associated with GCN2 activation, said modulators having the Formulae I, II, III, IV, V, VI, VII, and/or VIII.
Patent WO-2021222868-A1 (WO)
Inventor: PETERSON ANDERS
IPC: A61B1/24
Filed: 2021-04-30
Abstract: Dental periscopes having mounting clips configured to couple to mobile devices are disclosed. A patient can mount the dental periscope to a mobile device by coupling the mounting clip of the periscope to the mobile device. The patient can then use the mobile device-mounted dental periscope to capture image and/or video data of one or more dental structures. The captured image/video data can be sent to a remote system to obtain a remote dental diagnosis based on the captured data. The remote diagnosis may be an automated diagnosis generated by a trained machine learning classifier.
Patent WO-2021231933-A1 (WO)
Title: Anti-epileptic pharmaceutical compositions and use thereof
Inventor: LUI HUI
IPC: A61K31/195
Filed: 2021-05-14
Abstract: Compositions and methods for treating epilepsy in its various forms, which reduce the frequency, severity, or duration of seizure, are disclosed. Dosages, formulations, and routes of administration are also provided.
Patent WO-2021236544-A1 (WO)
Title: Pathology prediction based on spatial feature analysis
Inventor: LI XIAO
IPC: G06K9/00
Filed: 2021-05-17
Abstract: Systems and methods relate to processing digital pathology images. More specifically, depictions of objects of a first class (e.g., lymphocytes) and depictions of objects of a second class (e.g., tumor cells) are detected. Locations of each biological object depiction are identified, which are used to generate multiple spatial-distribution metrics that characterize where depictions of objects of a first class are located relative to objects of a second class. The spatial-distribution metrics are used to generate a result corresponding to a predicted biological state of or a potential treatment of a subject. For example, the result may predict whether and/or an extent to which lymphocytes have infiltrated a tumor, whether checkpoint blockade therapy would be an effective treatment for the subject, and/or whether a subject is eligible for a clinical trial.
Patent WO-2021257852-A1 (WO)
Title: Handheld device for measuring macular pigment
Inventor: PARK JOSHUA
IPC: A61B3/00
Filed: 2021-06-17
Abstract: An instrument includes a housing with a lower hand-held portion having a user-input button and a display for displaying an MPOD score for the user. The instrument further includes a viewing tube coupled to the hand-held portion. The viewing tube terminates in an eye cup. The viewing tube is transverse to the lower hand-held portion and transmits light from a light source in a direction toward the macula. The light source is an LED and provides two colored lights alternating at an initial frequency that is not perceptible by the user. The frequency decreases from the initial frequency until the user activates the user-input button in response to a frequency at which the user perceives a flicker of the two colored lights. The frequency at the perceived flicker relates to the MPOD score of the user. The MPOD score correlates to the amount of macular pigment.
Patent WO-2022031416-A1 (WO)
Title: Compositions and methods for prevention of viral infections and associated diseases
Inventor: JAIPRAKASH SHEWALE
IPC: A61K33/20
Filed: 2021-07-14
Abstract: Described herein are single-phase multi-component compositions and methods for their use reducing the viral load of infectious viruses on host organisms, including but not limited to Influenza A, Rhinovirus Type 14, Adenovirus Type 5, Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2; COVID-19 virus), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), and Human coronavirus 229E. The compositions described herein comprise a combination of an oxidative compound and a buffering system. The methods of use of these compositions as antiviral agents when applied to the oral, nasal, ocular, aural, anal, and urogenital cavities are described. Data shows the compositions to be effective in reducing influenza A and the human coronaviruses. In that regard, the single-phase multi-component compositions and methods for its antiviral use disclosed herein may be offer a single, effective product to combat multiple, concurrent pandemics.
Patent WO-2022015909-A1 (WO)
Title: System and method for concentrating gas
Inventor: BUDINGER MICHAEL
IPC: A61M16/10
Filed: 2021-07-15
Abstract: Systems and methods are provided for displaying status of a gas concentrator. The systems and methods include, for example, a display having a plurality of illuminable segments, The illuminable segments can be illuminated to form one or more displays indicating system status. The system status includes, for example, warmup, normal operation, low priority alarm (s), high-priority alarms, etc. In one embodiment, the systems and methods also read oxygen values of the gas concentrating system as one basis for determining system status. Other bases are also disclosed.
Patent WO-2022035571-A1 (WO)
Title: Method and apparatus for multi-rate neural image compression with stackable nested model structures
Inventor: JIANG WEI
IPC: G06K9/36
Filed: 2021-07-21
Abstract: A method of multi-rate neural image compression with stackable nested model structures is performed by at least one processor and includes iteratively stacking, on a first set of weights of a first neural network, a first plurality of sets of weights of a first plurality of stackable neural networks corresponding to a current hyperparameter, wherein the first set of weights of the first neural network remains unchanged, encoding an input image to obtain an encoded representation, using the first set of weights of the first neural network on which the first plurality of sets of weights of the first plurality of stackable neural networks is stacked, and encoding the obtained encoded representation to determine a compressed representation.
Patent WO-2022093341-A1 (WO)
Inventor: CHHODAVDIA AVDHESH
IPC: H04L9/08
Filed: 2021-07-27
Abstract: A method for secure key exchange. The method comprises receiving a request to certify a key from a communication partner at an interface between an access and tamper resistant circuit block and exposed circuitry. Within the access and tamper resistant circuit block, a first random private key is generated. A corresponding public key of the first random private key is derived, and a cryptographic digest of the public key and attributes associated with the first random private key is generated. The generated cryptographic digest is signed using a second random private key that has been designated for signing by one or more associated attributes. The public key and the signature are then sent to the communication partner via the interface.
Patent WO-2022026648-A1 (WO)
Inventor: ROSENZWEIG ANTHONY
IPC: C12N15/11
Filed: 2021-07-29
Abstract: The disclosure provides compositions comprising an inhibitory nucleic acid targeting IncExACTI, and methods of use thereof to improve cardiac function in a subject in need thereof. Specifically, the disclosure provides a cardiac long noncoding RNA (IncRNA), referred as IncExACT 1 (SEQ ID NO: 1 ), and inhibitory nucleic acids targeting IncExACT 1 for reducing expression of IncExACT 1 and/or Dachsous cadherin-related 2 (DCHS2) in a cell, e.g., a cell in a subject for improving cardiac function in a subject, wherein the subject has pathological cardiac hypertrophy and/or heart failure.