baber/WOPTO huggingface dataset:
Patent CA-3139356-A1 (CA)
Inventor: DAVIDSON DAVID ALLAN
IPC: C12Q1/6825
Filed: 2020-05-07
Abstract: L'invention concerne un moyen permettant d'amplifier et de détecter efficacement certaines séquences d'acides nucléiques à partir d'une population. La population sélectionnée peut en outre être caractérisée, par exemple par séquençage. Le procédé consiste en une amplification en phase solide et en phase soluble combinée.
Patent CA-3140952-A1 (CA)
Inventor: KAMBAYASHI TAKU
IPC: C07C401/00
Filed: 2020-05-18
Abstract: Compositions and methods for treating obesity are provided. In certain embodiments, the compositions comprise the topical vitamin D3 derivative MC903. In other embodiments, the compositions systemically increase TSLP levels in a subject. In yet other embodiments, the compositions include TSLP peptide isoforms and/or adeno-associated viral vectors containing TSLP-expressing sequences. Methods using these compositions increase TSLP levels in the subject and cause selective loss of white adipose tissue without loss in muscle mass.
Patent CA-3141229-A1 (CA)
Title: Novel cancer antigens and methods
Inventor: KASSIOTIS GEORGE
IPC: C07K14/00
Filed: 2020-06-26
Abstract: There are disclosed inter alia polypeptides and nucleic acids encoding said polypeptides which are useful in the treatment, prevention and diagnosis of cancer, particularly ovarian cancer.
Patent CA-3141648-A1 (CA)
Title: Novel anti-hepatitis b virus antibody and uses thereof
Inventor: LUO WENXIN
IPC: A61K39/42
Filed: 2020-05-22
Abstract: Disclosed are antibodies to anti-hepatitis B surface antigen (HBsAg) (especially humanized antibodies), nucleic acid molecules encoding same, methods for preparing same, and pharmaceutical compositions containing same. The antibodies have higher affinity for HBsAg at neutral pH than at acidic pH, thereby significantly enhancing the virus clearance efficiency and prolonging the virus inhibition time. The antibodies and the pharmaceutical compositions can be used for preventing and/or treating HBV infections or diseases related to HBV infections (e.g., hepatitis B), for neutralizing the virulence of HBV in a subject (e.g., a human), for reducing the serum level of HBV DNA and/or HBsAg in the body of the subject, or for activating the humoral immune response of the subject (e.g., a chronic HBV infected or chronic hepatitis B patient) against HBV.
Patent CA-3147657-A1 (CA)
Title: Icosapent ethyl pour maintenir le controle des lipoproteines de basse densite
Inventor: ROWE JONATHAN
IPC: A61K31/232
Filed: 2011-03-04
Abstract: La présente invention concerne lutilisation de leicosapentaénoate éthyl pour maintenir le contrôle de la lipoprotéine de faible densité chez un sujet suivant une thérapie de statine stable à triglycérides élevés.
Patent CA-3149370-A1 (CA)
Title: Methode de determination de risque de stress chronique et d'accident vasculaire cerebral
Inventor: MALAN LEONE
IPC: G01N33/68
Filed: 2020-07-31
Abstract: L'invention concerne des méthodes de détermination d'un risque de stress chronique et d'accident vasculaire cérébral. Plus particulièrement, l'invention concerne un indice de pronostic précoce pouvant être utilisé pour prédire un risque de stress chronique et d'accident vasculaire cérébral. L'invention concerne une méthode d'évaluation du risque de développer un stress chronique et un accident vasculaire cérébral, la méthode consistant à obtenir un échantillon biologique chez un individu ; à mesurer les niveaux d'un ensemble de biomarqueurs dans l'échantillon biologique obtenu chez l'individu ; à mesurer les niveaux d'un ensemble de marqueurs cliniques de l'individu ; à utiliser un ordinateur pour générer de manière programmatique un indice en fonction des niveaux de biomarqueur dans l'échantillon biologique obtenu chez l'individu en combinaison avec des niveaux du marqueur clinique de l'individu ; et à utiliser l'indice pour identifier une probabilité pour l'individu de subir un stress chronique et un accident vasculaire cérébral.
Patent CA-3149545-A1 (CA)
Inventor: WATKINS GREGORY A
IPC: A61K47/12
Filed: 2020-08-27
Abstract: A composition comprising a small molecule therapeutic agent and a polyprotic acid compound or a mixture of two monoprotic acid compounds is described. The polyprotic acid is present in an amount that (i) is equal to or less than the molar amount of the therapeutic agent and (ii) provides a total number of acid hydrogens that exceeds the stoichiometric equivalent for the molar amount of therapeutic agent. The two or more monoprotic acids are present such that each monoprotic acid is in an amount that is equal to or less than the molar amount of the therapeutic agent and together the two or more monoprotic acids provide a total number of acid hydrogens that exceeds the stoichiometric equivalent for the molar amount of therapeutic agent. The polyprotic acid or mixture of monoprotic acids provide a composition that delivers the therapeutic agent for a sustained period of time.
Patent CA-3152807-A1 (CA)
Inventor: PERRIN STEVEN
IPC: A61K31/555
Filed: 2020-07-24
Abstract: La présente invention concerne l'utilisation de CuPTSM dans des méthodes et des compositions pour traiter des sujets atteints d'une maladie neurodégénérative. Les sujets présentant une maladie neurodégénérative peuvent avoir, par exemple, la sclérose latérale amyotrophique (SLA).
Patent CA-3155403-A1 (CA)
Title: Infrared temperature measurement and stabilization thereof
Inventor: MASTON ROBERT
IPC: G01J5/0806
Filed: 2019-05-24
Abstract: Infrared (IR) temperature measurement and stabilization systems, and methods related thereto are provided. One or more embodiments passively stabilizes temperatures of objects in proximity and within the path between an infrared (IR) sensor and target object. An overmolded sensor assembly may include an IR sensor, which may include a sensing element or IR element and a circuit or signal processor. The IR element may be thermally bonded with a frame or conductive top hat.
Patent CA-3159802-A1 (CA)
Inventor: LV MING
IPC: A61K47/68
Filed: 2020-11-27
Abstract: L'invention concerne une protéine de liaison à un antigène séparée, contenant au moins une CDR dans VH ayant la séquence d'acides aminés telle que représentée dans SEQ ID NO : 1 ou SEQ ID NO : 46, et au moins une CDR dans VL ayant la séquence d'acides aminés telle que représentée dans SEQ ID NO : 2. L'invention concerne également un immunoconjugué contenant la protéine de liaison à l'antigène séparée, un acide nucléique codant pour la protéine de liaison à l'antigène séparée, un excipient contenant la protéine de liaison à l'antigène séparée, une cellule contenant l'acide nucléique ou l'excipient, un procédé de préparation de la protéine de liaison à l'antigène séparée, et l'utilisation de la protéine de liaison à l'antigène séparée.
Patent CA-3160290-A1 (CA)
Title: Power tool
Inventor: HOFFMAN RONALD J
IPC: A01G3/06
Filed: 2022-05-11
Abstract: A subassembly for a trimmer head of a power tool, the subassembly including:  a flywheel; and_a cartridge including a segment of trimmer line, wherein the cartridge is removably keyed to the flywheel, wherein the subassembly is configured to be operatively coupled to a motor of the power tool, and wherein the subassembly is removably positionable in a housing of the power tool.
Patent CA-3160348-A1 (CA)
Title: Hydrotraitement catalytique de charges d'alimentation
Inventor: LAMMINPAA KAISA
IPC: C10G45/16
Filed: 2020-12-18
Abstract: L'invention concerne un procédé d'hydrotraitement de charges d'alimentation recyclées ou renouvelables avec une suspension de microparticules catalytiques, et un procédé de fabrication de la suspension de microparticules catalytiques.
Patent CA-3163037-A1 (CA)
Title: Encryption for message queues
Inventor: GIBLIN CHRISTOPHER
IPC: H04L9/28
Filed: 2021-01-10
Abstract: A targeted, topic-based encryption in a publish-subscribe message queue. Topic-based encryption driven by encryption policies for both storing and receiving messages uses activity tracking and logging to ensure confidentiality of certain topics associated with stored encrypted messages. Authentication of both publisher and consumer ensure encryption and decryption keys are used in confidence.
Patent CA-3164863-A1 (CA)
Title: Purge stand
Inventor: OTT JOSHUA D
IPC: F17D1/00
Filed: 2022-06-22
Abstract: A purging device includes a main body having an inlet disposed at a first end of the main body and an outlet disposed at a second end of the main body. A base is positioned adjacent the first end of the main body, a testing port is disposed along the main body of the purging device, and a control valve is disposed between the inlet of the main body and the outlet of the main body.
Patent CA-3166386-A1 (CA)
Title: Treatment of cancer with cdk12/13 inhibitors
Inventor: MURPHY ERIC A
IPC: C07D401/04
Filed: 2020-12-23
Abstract: Provided herein are compositions and methods for the treatment of a triple-negative breast cancer, ovarian cancer and castration-resistant prostate cancer. Said compositions comprise CDK12/13 inhibitors.
Patent CA-3167526-A1 (CA)
Title: A microfluidic detection system and a microfluidic cartridge
Inventor: BAU-MADSEN NIELS KRISTIAN
IPC: G01N27/416
Filed: 2015-06-15
Abstract: The present invention relates to a microfluidic detection system comprising a microfluidic cartridge and a detector assembly. The microfluidic cartridge comprises a first and a second side and at least one flow channel and an inlet to the flow channel(s) for feeding a liquid sample, the flow channel(s) comprises a plurality of first optical detection sites. The detector assembly comprises a slot for inserting the microfluidic cartridge and a first fixed light source with a beam path and an optical reader for reading out optical signals from at least one of said first optical detection site(s). The detector assembly and the microfluidic cartridge are constructed such that when said microfluidic cartridge is inserted to a first predetermined position into said slot, one of the first optical detection sites of the microfluidic cartridge is positioned in the beam path of the first light source, and when said cartridge is inserted to a second predetermined position into said slot, another one of the first optical detection sites of the microfluidic cartridge is positioned in the beam path of the first light source.
Patent CA-3174181-A1 (CA)
Inventor: ISERNHAGEN CHRISTOPH FABIAN
IPC: G01N21/95
Filed: 2021-07-26
Abstract: The present invention relates to a method and an arrangement for training at least one neural network for locating bony parts present in a poultry leg (10). The present invention relates further to a method and an apparatus for locating bony parts present in a poultry leg (10), wherein the method comprises the steps conveying the poultry legs (10) in a conveying direction (16) by means of a conveying device (23), acquiring digital images (25) of the front side or back side of each of the poultry legs (10) conveyed past the imaging system (24) by means of a first optical imaging system (24), sequentially providing the digital images (25) as input data to a first neural network configured for locating the bony parts, wherein the first neural network for locating the bony parts has been trained by a method according to any one of claims 1 to 6, and determining position data (31) of the bony parts by means of the first neural network and providing the position data (31), for display and/or transmission, to a downstream machine (26) for processing the poultry legs (10) on the basis of the determined position data.
Patent CA-3175275-A1 (CA)
Inventor: EDELMANN KURT
IPC: A61K47/68
Filed: 2021-03-19
Abstract: La présente invention concerne des anticorps qui se lient à la mucine 17 (MUC17) humaine et de singe. De plus, l'invention concerne un système de détection comprenant de tels anticorps. Les anticorps ou le système de détection peuvent être utilisés pour détecter ou quantifier la MUC17, pour diagnostiquer une maladie associée à la MUC17, pour la stratification de patients, surveiller la progression d'une maladie, et évaluer la réponse thérapeutique.
Patent CA-3175414-A1 (CA)
Inventor: LEE JOO HEE
IPC: C12N15/75
Filed: 2022-03-11
Abstract: The present application relates to a novel serine protease variant.
Patent CA-3175632-A1 (CA)
Inventor: SAHGAL ABHINANDAN
IPC: G06F3/00
Filed: 2021-04-15
Abstract: A document management system manages documents. The documents are managed such that the documents may be shared with one or more users during an online sharing session for electronic signing. During the online sharing session, one or more documents are collaboratively reviewed by one or more participants of the online sharing session. The one or more documents are e-signed at least one of the participants of the online sharing session.
Patent CA-3176401-A1 (CA)
Title: Methods and systems for analysis of receptor interaction
Inventor: ZHANG WEN
IPC: G16B15/30
Filed: 2021-04-21
Abstract: A computational framework for high-throughput mapping, validating, and predicting receptor sequence interactions is described.
Patent CA-3176932-A1 (CA)
Inventor: FARRELL DAVID J
IPC: A61M25/00
Filed: 2021-04-29
Abstract: La présente invention concerne un produit dispositif médical (10) qui comprend un emballage (12) délimitant une cavité intérieure (14). La cavité intérieure comprend un premier compartiment (16) et un second compartiment (18) qui sont séparés par une barrière perméable à la vapeur (20). Un liquide donneur de vapeur (22) est situé dans le premier compartiment, et le liquide donneur de vapeur donne une vapeur (28). Un dispositif médical (24) et un élément d'aspiration (26) sont situés dans le second compartiment. Le dispositif médical comprend au moins une partie qui est activée par la vapeur. L'élément d'aspiration aspire la vapeur à partir du premier compartiment à travers la barrière et dans le second compartiment. La vapeur active la partie du dispositif médical.
Patent CA-3178307-A1 (CA)
Title: Systems, devices, and methods for improved analyte sensor accuracy and fault detection
Inventor: BUDIMAN ERWIN S
IPC: A61B5/145
Filed: 2021-06-07
Abstract: Various embodiments of systems, devices and methods for improving the accuracy of an analyte sensor and for detecting sensor fault conditions are disclosed. According to some embodiments, these systems, devices, and methods can utilize a first data collected by a glucose sensor and a second data collected by a secondary sensing element. In some embodiments, the secondary sensing element can be one of a lactate sensing element, a ketone sensing element, or a heart rate monitor, among others.
Patent CA-3180543-A1 (CA)
Title: Downhole electromagnetic logging instrument
Inventor: ZHANG QINGSHENG
IPC: E21B47/26
Filed: 2021-04-20
Abstract: A downhole electromagnetic logging instrument (3), comprising an emission system, a magnetic field array sensor (9), and a control module, the emission system and the magnetic field array sensor (9) both being connected to the control module; the emission system comprises an upper emission coil (12) and a lower emission coil (13), the upper emission coil (12) and the lower emission coil (13) are respectively arranged above and below the magnetic field array sensor (9), and the upper emission coil (12) and the lower emission coil (13) generate magnetic fields of opposite polarities, allowing the magnetic fields to be concentrated at the magnetic field array sensor (9); a casing (14) produces a secondary magnetic field, and the magnetic field array sensor (9) receives the secondary magnetic field to complete measurement of the casing (14).
Patent CA-3181698-A1 (CA)
Inventor: MASON CHRISTOPHER W
IPC: B01D35/02
Filed: 2022-11-10
Abstract: A water sediment filter assembly includes a screen member and a drain port which permits the removal of collected debris. The water sediment filter assembly includes a valve member which can be moved to different positions to permit the draining of collected sediment through the drain port.
Patent CA-3182767-A1 (CA)
Title: Method and system for detection of ruleset misconfiguration
Inventor: WALDENBORG ANDERS
Filed: 2022-11-25
Abstract: A method and system for detecting ruleset misconfiguration in a computer network. The method including: generating a set of sample data flows; evaluating each of the set of sample data flows against a predetermined definition to generate a flow descriptor for each of the set of sample data flows; evaluating each of the flow descriptors against a ruleset; and generating a summary of how each of the flow descriptors perform with respect to the ruleset. The system including: a data flow sample retrieval module configured to generate flows; a policy engine configured to store and retrieve a ruleset; a packet processing engine configured to evaluate each of the data flows against a predetermined definition to generate a flow descriptor for each flows, evaluate each of the flow descriptors against a ruleset; and generate a summary of how each of the flow descriptors perform with respect to the ruleset.
Patent CA-3185112-A1 (CA)
Title: Electronic vaporization device
Inventor: LI YUANJIAN
IPC: A24F40/46
Filed: 2022-12-09
Abstract: The present disclosure relates to an electronic vaporization device, including a vaporization body including a heating pot configured to heat and vaporize an aerosol-generating substrate, a vaporization seat configured to accommodate the heating pot, and a power supply device configured to supply electrical energy to the heating pot. The vaporization seat includes an electrode device electrically connecting the heating pot and the power supply device, and the heating pot is detachably embedded in the vaporization seat and is detachably electrically connected to the electrode device. In the present disclosure, the heating pot is detachably electrically connected to the electrode device to allow quick disassembly and assembly of the heating pot, so that the heating pot can be conveniently disassembled for cleaning.
Patent CA-3185868-A1 (CA)
Inventor: SCHIFFRIN EDUARDO
IPC: A61P35/00
Filed: 2021-07-23
Abstract: La présente invention concerne des composés et des compositions destinés à être utilisés dans le traitement du cancer dans le cadre d'une thérapie par cellules T réceptrices d'antigènes chimériques (CAR-T). En particulier, la présente invention concerne des molécules de liaison IL-18, par exemple la protéine de liaison IL-18 (IL-18BP), à utiliser dans la thérapie par cellules T à récepteur d'antigène chimérique (CAR-T) comme modulateur pour éviter ou réduire à un minimum les effets secondaires.
Patent CA-3185988-A1 (CA)
Inventor: BARKER JERRY
IPC: A61F2/14
Filed: 2021-07-14
Abstract: Devices, kits and tools that facilitate pre-loading, storage, transportation and small incision, partial thickness corneal replacement procedures, including deep lamellar endothelial keratoplasty (DLEK), Descemet's stripping endothelial keratoplasty (DSEK) and Descemet's stripping automated endothelial keratoplasty (DSAEK), using donor eye tissue are provided
Patent CA-3188536-A1 (CA)
Title: Process for precipitating a mixed hydroxide
Inventor: BERGNER BENJAMIN JOHANNES HERBERT
IPC: C01G53/00
Filed: 2021-08-03
Abstract: Process for precipitating a mixed hydroxide of TM wherein TM comprises Ni and at least one of Co and Mn and, optionally, Al, Mg, Zr or Ti from an aqueous solution of salts of such transition metals or of Al or of Mg, wherein such process is carried out in a stirred vessel and comprises the step of introducing a 10 to 40% by weight aqueous solution of ammonia and an aqueous solution of transition metal salts through at least two inlets into said stirred vessel wherein the distance of the locations of introduction of TM and of ammonia is equal or less than 12 times the hydraulic diameter of the tip of the inlet of the ammonia, and wherein an aqueous solution ofalkali metal hydroxide is added separately from the at least two inlets.
Patent CA-3189026-A1 (CA)
Title: Pharmaceutical composition containing cerium compound as active ingredient
Inventor: KAWAGUCHI TSUNETAKA
IPC: A61P13/12
Filed: 2021-04-30
Abstract: The primary problem of the present invention is to provide a novel pharmaceutical composition. The present invention relates to a pharmaceutical composition containing a cerium compound as an active ingredient.
Patent CA-3192436-A1 (CA)
Inventor: SETZER ANDREAS
IPC: A24D3/06
Filed: 2021-09-10
Abstract: The invention relates to a device (1) for filtering smoke, in particular tobacco and/or cannabis cigarette filter, having a jacket (2), there being provided in the jacket (2) at least a first section (11), a second section (12) and a third section (13), the second section (12) being arranged between the first section (11) and the third section (13), a first nonwoven filter material (3) being provided in the first section (11), a porous filter material (4) being provided in the second section (12), and a second nonwoven filter material (5) being provided in the third section (13); a fourth section (14) being provided in the jacket (2), the third section (13) being arranged between the second section (12) and the fourth section (14), and the fourth section (14) being designed such that a pressure drop across the fourth section (14) is smaller than a pressure drop across the third section (13) as flow passes through the jacket (2).
Patent CA-3193162-A1 (CA)
Title: Method and system for contextual notification
Inventor: HARDING IAN
IPC: G08B25/00
Filed: 2021-09-20
Abstract: Determining, generating, and issuing a contextual alert message to a user regarding an alert condition of a process system is provided. Described is determining variable data from a sensor associated with a process system, transmitting a first set of variable data from the sensor to a server and using the server to develop an alert classification model using the first set of variable data, where the alert classification model contains contextual information about an alert condition of the process system, transmitting a second set of data from the sensor to the server and using the server to compare the second set of data to a threshold value to determine if the process system is in an alert condition or approaching an alert condition.
Patent CA-3193964-A1 (CA)
Title: Systems and methods of utility data triangulation to verify data accuracy
Inventor: TUCKER JOHN
IPC: G06Q30/04
Filed: 2023-03-23
Abstract: Systems and methods may be provided to receive, at a server, a utility bill and interval data for a user of an energy utility, and store the received utility bill and interval data in a database system communicatively coupled to the server. The received utility bill may include a date range for the bill and a tariff. The received interval data may include data used by the energy utility for determining costs. A calculation engine of the server may determine a model bill based on the received utility bill and the interval data. The server may determine an accuracy of a utility bill issued by the energy utility to by determining whether the model bill matches the utility bill. The server may verify the utility bill, the interval data, and the tariff as accurate when the model bill matches the utility bill based on the accuracy determination.
Patent CA-3197411-A1 (CA)
Inventor: LEE JUSTIN DONGHOON
IPC: B01D1/30
Filed: 2021-11-18
Abstract: A system and method for cleaning of a forced-circulation evaporative crystallizer. The crystallizer is used to produce salt solids and includes a circulation pump, a heat exchanger, a separator, and a vapor processor. Solids deposits accumulate during salt solids production within at least one of the circulation pump, heat exchanger, and separator. A solids deposits metric representative of an amount of the accumulated solids deposits is measured. The solids deposits metric is determined to deviate from a baseline by at least a cleaning threshold. Certain determinations are made based on the solids deposits metric: determining a cleaning mode and at least one of a type of cleaning solution and a duration for which at least one of the circulation pump, heat exchanger, and separator is to be cleaned. At least one of the circulation pump, heat exchanger, and separator is then cleaned in accordance with those determinations.