baber/WOPTO huggingface dataset:
Patent CA-3096691-A1 (CA)
Inventor: FU XIANG-DONG
IPC: A61K48/00
Filed: 2019-04-11
Abstract: Provided herein is a method of reprogramming a non-neuronal cell to a neuron. Aspects of the present disclosure relate to using cell reprogramming agent suppresses the expression or activity of PTB to convert a non-neuronal cell into a neuron. Also provided herein is a method of treating neurodegenerative disease by reprogramming non-neuronal cells in vivo to functional neurons.
Patent CA-3096899-A1 (CA)
Title: System and method for automated document adjudication communicating clinical trial activities with preparation for efiling
Inventor: FENECH LIDIA
IPC: G06Q10/10
Filed: 2020-10-21
Abstract: The system and method to process to identify, assess, adjudicate clinical trial documents, and a proprietary communication process with users and senders each transaction of activity up to the point of eFiling for correct documents in real time including escalation pathways as needed. The system and methodology generates a tracking document for each transaction within the system. A secure server is used to send and receive all study documents within the system using transmission capabilities. Each document, new or updated, is tracked upon receipt using a proprietary methodology, each error identified using the proprietary adjudication is tracked and prepared for communication to the user/sender in real time. The correction attempts is predetermined within the system, and escalation pathways are implemented at specified time points. All transactions/activities are tracked and prepared for eFiling within a closed cloud based system in real-time.
Patent CA-3097217-A1 (CA)
Title: Systemes de solvant destines a etre utilises dans la production de batterie au lithium-ion
Inventor: JIANG XIN
IPC: H01M4/02
Filed: 2018-04-27
Abstract: Dans le procédé de production d'une batterie au lithium-ion, un ou plusieurs composés de formule 1, 2, 3 ou 4 (par exemple, le N, N-diméthylpropionamide), est utilisé en tant que solvant dans l'étape de formation d'une suspension à partir d'un matériau actif (par exemple, l'oxyde de cobalt de lithium), d'un agent conducteur (par exemple, le noir de carbone), et d'un polymère de liaison (par exemple, le fluorure de polyvinylidène).
Patent CA-3098058-A1 (CA)
Inventor: MUNRO JOHN
IPC: B28B21/72
Filed: 2020-11-04
Abstract: Il est décrit un élément en béton composite préfabriqué à utiliser dans un environnement dégout corrodant. Lélément en béton a une partie en béton fabriqué et renforcé creuse avec au moins une extrémité ayant des détails de branchement et un revêtement en plastique interne, prémoulé et résistant à la corrosion. Le revêtement en plastique marque une partie intérieure de lélément en béton creux et des détails de branchement pour fournir des faces de revêtement dans un joint assemblé afin de limiter lexposition à travers ledit joint de ladite partie en béton à des matières corrosives se produisant dans ledit environnement dégout. Des éléments en béton composite préfabriqués peuvent être assemblés bout à bout à un joint pour former un système dégout en béton. Il est également décrit un procédé de préfabrication dun tel élément en béton composite.
Patent CA-3099437-A1 (CA)
Inventor: LEWIS CAMERON
IPC: F17C7/00
Filed: 2019-05-17
Abstract: A hydrostatically compensated compressed air energy storage system may include an accumulator disposed underground, a gas compressor/expander subsystem in fluid communication with the accumulator interior via an air flow path; a compensation liquid reservoir spaced apart from the accumulator and in fluid communication with the layer of compensation liquid within the accumulator via a compensation liquid flow path; and a first construction shaft extending from the surface of the ground to the accumulator and being sized and configured to i) accommodate the passage of a construction apparatus therethrough when the hydrostatically compensated compressed air energy storage system is being constructed, and ii) to provide at least a portion of one of the air flow path and the compensation liquid flow path when the hydrostatically compensated compressed air energy storage system is in use.
Patent CA-3100186-A1 (CA)
Inventor: YU JAE WON
IPC: C08L101/00
Filed: 2018-05-25
Abstract: La présente invention concerne une composition pour la réparation de tissu à l'aide d'un polymère biocompatible non toxique; et son procédé de fabrication. La présente invention concerne une composition pour la réparation tissulaire, la composition comprenant un copolymère obtenu à partir de la polymérisation d'un polymère biocompatible hydrophobe et d'un polymère biocompatible hydrophile, la composition étant dans une phase colloïdale dans laquelle le copolymère est dispersé dans l'eau; et son procédé de fabrication.
Patent CA-3100723-A1 (CA)
Title: Testing of a network of hazard warning devices
Inventor: VANNEBO PER JOHAN
IPC: G08B29/12
Filed: 2018-05-29
Abstract: Disclosed is an alarm unit electrically connected to a loop circuit in a networked alarm system, the loop circuit being electrically connected to a first power source and a first controller, the alarm unit including: a current sink, a second controller for controlling the current sink, wherein the second controller performs an alarm unit status test including: receiving instructions from the first controller to actuate the current sink, and actuating the current sink.
Patent CA-3101149-A1 (CA)
Title: Chemical-resistant quartz-based casting composition and method of making a chemical-resistant concrete
Inventor: ANDERSON MICHAEL W
IPC: B28C7/04
Filed: 2020-11-30
Abstract: A quartz-based casting composition provides excellent resistance to attack by chemicals, including weak and strong acids. The quartz-based casting composition is useful as concrete in various construction applications where corrosion resistance is needed. The casting composition includes a dry component and a wet component. The dry component includes about 25% to about 100% by weight quartz and the corrosion resistance increases with increasing quartz content. A method of making a chemical-resistant concrete is also provided.
Patent CA-3102816-A1 (CA)
Inventor: MURPHY BRIAN P
IPC: H04L69/40
Filed: 2019-06-06
Abstract: A computer-implemented method, computer program product and computing system for: establishing connectivity with a plurality of security-relevant subsystems within a computing platform; receiving a unified query from a third-party concerning the plurality of security-relevant subsystems; distributing at least a portion of the unified query to the plurality of security-relevant subsystems; and effectuating the at least a portion of the unified query on each of the plurality of security-relevant subsystems to generate a plurality of result sets.
Patent CA-3104418-A1 (CA)
Title: Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
Inventor: BHANDARI ASHOK
IPC: C07K7/02
Filed: 2019-07-12
Abstract: The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases.
Patent CA-3105535-A1 (CA)
Inventor: HAMM KATHRIN
IPC: A47G9/02
Filed: 2019-10-08
Abstract: Disclosed is a weighted material that is configured to effectuate deep pressure therapy to a person when a piece of the weighted material is used as a blanket over the person's body. A length of layered yarn is interlooped to form the piece of weighted material. The layered yarn includes an outer tube extending longitudinally from a first end to a second end. The outer tube defines a conduit extending longitudinally therethrough from the first end to the second end. A  plurality of inner layers of material are disposed within the conduit and extend longitudinally from the first end to the second end. The interlooped length of yarn, by itself, is configured and sufficiently weighted to effectuate deep pressure therapy to a person when the blanket lies over the person's body. Various other systems and methods are also disclosed.
Patent CA-3106074-A1 (CA)
Title: Methode de prevention ou de traitement de la neuropathie peripherique ou de la douleur accompagnant une maladie dans laquelle une neuropathie peripherique ou un trouble astrocytai re est reconnu
Inventor: ISHIDA HAYATO
IPC: A61K39/395
Filed: 2019-07-10
Abstract: La présente invention vise à fournir une nouvelle méthode de prévention ou de traitement de la neuropathie périphérique, ou un méthode de prévention ou de traitement de symptômes de douleur dus à une maladie dans laquelle une neuropathie périphérique ou un trouble astrocytaire est reconnu. La présente invention concerne en outre un agent de prévention ou de traitement de la neuropathie périphérique, ou de symptômes de douleur dus à une neuropathie périphérique ou à une maladie dans laquelle une neuropathie périphérique ou un trouble astrocytaire est reconnu, ledit agent contenant une substance inhibitrice de RGM.
Patent CA-3110176-A1 (CA)
Title: Advanced cardiac waveform analytics
Inventor: CANTILLON DANIEL J
IPC: A61B5/363
Filed: 2019-08-20
Abstract: This disclosure describes systems and methods for electrocardiographic waveform analysis, data presentation and actionable advisory generation. Electrocardiographic waveform data can be received from a wearable device associated with a patient. A mathematical analysis can be performed on the electrocardiographic waveform data to provide cardiac analytics. A visualization of the cardiac analytics on a dashboard display can be generated. A value can be based on a comparison of the cardiac analytics to at least one baseline value for the patient; and a decision of whether or not to generate an actionable advisory for the electrocardiographic waveform data can be made based on the value. When the actionable advisory is generated, the actionable advisory is sent to one or more medical professionals, where it can be modified, and displayed with the visualization of the cardiac analytics.
Patent CA-3110672-A1 (CA)
Title: Method and apparatus loading of cases with items
Inventor: LANGEN H J PAUL
IPC: B65G65/02
Filed: 2021-02-26
Abstract: A system is disclosed for loading cases with items comprising: an item delivery apparatus operable to deliver a plurality of items to a transfer station; a collation platform operable to support a group of items; a pedestal apparatus operable to support the group of items; a first transfer apparatus operable to transfer a plurality of items from the item delivery apparatus to the collation platform. A second transfer apparatus transfers the group of items from the collation platform to the pedestal apparatus. At least one movement rod moves the group of items. A case movement apparatus such as a six-axis robotic arm is moves an erected case in a path that sheaths a group of items located on said pedestal apparatus with an erected case. The path of the case may have a tilted position and include an arced pivoting movement.
Patent CA-3112400-A1 (CA)
Title: Homopolar linear synchronous machine
Inventor: JEDINGER ALEXANDER
IPC: H02K3/28
Filed: 2019-09-18
Abstract: Homopolar linear synchronous machines (200) are provided herein that include a mover device (111). The mover device (111) includes a cold plate with ferromagnetic cores extending through slots in the cold plate. Layers of armature coils are located around the ferromagnetic cores on opposite sides of the cold plate. The mover device (111) further includes at least one field coil.
Patent CA-3114451-A1 (CA)
Title: Recepteur de lymphocytes t reconnaissant un antigene ssx2
Inventor: LI YI
IPC: C12N15/11
Filed: 2019-09-20
Abstract: La présente invention concerne un récepteur de lymphocytes T (TCR) capable de se lier spécifiquement à un peptide court KASEKIFYV dérivé d'un antigène SSX2, le peptide court KASEKIFYV d'antigène pouvant former un complexe avec le HLA A0201 et être présenté au niveau de la surface cellulaire conjointement avec celui-ci. L'invention concerne en outre une molécule d'acide nucléique codant pour le TCR et un vecteur comprenant la molécule d'acide nucléique. De plus, la présente invention concerne en outre une cellule pour la transduction du TCR selon la présente invention.
Patent CA-3117173-A1 (CA)
Inventor: PEI LEI
IPC: G06K9/62
Filed: 2021-05-05
Abstract: A method utilizes a framework for transaction categorization personalization.  A  transaction record is received. a baseline model is selected from a plurality of machine learning models. An account identifier, corresponding to the transaction record using the baseline model, is selected. The account identifier for the transaction record is presented.
Patent CA-3118614-A1 (CA)
Inventor: ARSLAN AYSU
IPC: C08G18/75
Filed: 2019-11-05
Abstract: The present invention in general relates to acrylate end-capped urethane-based polymers, which are in particular characterized by the presence of at least 3 acrylate end-groups, thereby making them particularly suitable for further processing using multiple kinds of technologies such as 2-photon polymerization, stereolithography (SLA printing), electrospinning, film casting, porogen leaching, extrusion based 3D-printing, spray drying, cryogenic treatment, coatings, cross-linkable micelles, spincoating, and electrospraying.
Patent CA-3120680-A1 (CA)
Inventor: STROBEL ANDY
IPC: B01F27/73
Filed: 2021-06-02
Abstract: Mixing systems that include a mixer housing and one or more disk assemblies for mixing and processing materials is disclosed. The disks rotate to mix an additive into the material and to carry agglomerated solids toward a discharge of the mixing system. The disks may have a plurality of fingers or lobes which extend from a central portion of the disks.
Patent CA-3120905-A1 (CA)
Inventor: SANZ HERRANZ YOLANDA
IPC: C12N1/20
Filed: 2019-11-27
Abstract: La présente invention concerne des bactéries Christensenellaceae comprenant une souche de Christensenella minuta DSM 32891, des composants cellulaires, des métabolites et des molécules sécrétées par celles-ci, et des compositions qui comprennent les produits mentionnés ci-dessus, ainsi que l'utilisation de ladite souche pour la prévention et/ou le traitement de troubles de l'humeur ou de troubles affectifs, tels que la dépression, les troubles liés au stress, les troubles liés à l'anxiété et la migraine.
Patent CA-3123651-A1 (CA)
Title: Strain of saccharomyces cerevisiae var. boulardii for treating infectious diseases of the oral cavity
Inventor: BALLET NATHALIE
IPC: A61P1/02
Filed: 2019-12-19
Abstract: The invention relates to a yeast strain of Saccharomyces cerevisiae var. boulardii for the treatment and/or prevention of infectious diseases of the oral cavity, such as dental caries and periodontal diseases.<i /> This strain can be used alone or in combination with the inactive dry form of a yeast strain of Saccharomyces cerevisiae.
Patent CA-3126778-A1 (CA)
Inventor: HOET RENE
IPC: A61P9/00
Filed: 2020-01-16
Abstract: La présente invention concerne un procédé permettant de déterminer si un sujet humain ou animal souffre d'un stress oxydatif, est approprié pour être traité avec un antioxydant et/ou un piégeur de radicaux libres, et/ou est approprié pour être traité avec un agoniste de guanylyle cyclase soluble (sGC), en particulier avec un activateur de sGC, ledit procédé comprenant les étapes consistant à fournir un échantillon de tissu ou de liquide à partir dudit sujet, et à déterminer si ledit échantillon est caractérisé par la présence, la régulation à la hausse ou la surexpression de sGC comprenant une sous-unité ß1 sans hème.
Patent CA-3133569-A1 (CA)
Inventor: CHAUDHARY BHARAT
IPC: C08L43/04
Filed: 2020-02-11
Abstract: A moisture-curable polyethylene formulation comprising a (hydrolyzable silyl group)-functional polyethylene copolymer and a condensation cure catalyst. The formulation is designed to be rapidly moisture curable under ambient conditions. Also methods of making and using same; cured polymer products made therefrom; and articles containing or made from same.
Patent CA-3134450-A1 (CA)
Inventor: DAVIS EMILY
IPC: H02J13/00
Filed: 2021-10-15
Abstract: A refuse vehicle includes a chassis, an energy storage device supported by the chassis, a body assembly, and a power distribution unit. The energy storage device is configured to provide electrical power to a prime mover. Activation of the prime mover selectively drives the refuse vehicle. The body assembly is configured for storing refuse and is supported by the chassis.  The power distribution unit is coupled to the energy storage device and is configured to control power transmission outward from the energy storage device, between the chassis and the body assembly. The body assembly includes a controller that communicates with the power distribution unit to adjust a flow of electrical power from the energy storage device to the body assembly.
Patent CA-3136901-A1 (CA)
Title: Clothing article having terry cloth adjacent to non-terry cloth
Inventor: ALMOG ELI
IPC: A41D31/12
Filed: 2020-04-16
Abstract: A garment for a human wearer includes: a terry garment-region having terry-knit cloth; and a non-terry garment-region having non-terry-knit cloth. The terry garment-region is directly bordering and adjacent to the non-terry garment-region. The terry garment-region and the non-terry garment-region are a seamless continuation of each other. Similarly, a continuous fabric for making clothes includes: a terry fabric-region having terry-knit cloth, and an adjacent and immediately bordering non- terry fabric-region having non-terry-knit cloth.
Patent CA-3137265-A1 (CA)
Inventor: NAYANI ANIL
IPC: C07D487/00
Filed: 2020-04-30
Abstract: La présente invention concerne une composition parentérale aqueuse stable et prête à l'emploi comprenant du pemetrexed, la composition comprenant du pemetrexed disodique, un mélange d'antioxydants et des excipients pharmaceutiquement acceptables. La présente invention concerne en outre un procédé de préparation de ladite composition.
Patent CA-3147263-A1 (CA)
Title: Methodes et compositions pour traiter l'hypertension arterielle pulmonaire
Inventor: SIMONS MICHAEL
IPC: A61P9/02
Filed: 2020-07-14
Abstract: Dans divers aspects et modes de réalisation, l'invention concerne des méthodes de traitement de l'hypertension artérielle pulmonaire par inhibition de la transition endothéliale-mésenchymateuse. L'invention concerne une méthode de traitement de l'hypertension artérielle pulmonaire (HTAP) chez un sujet, méthode comprenant l'administration au sujet d'un agent qui module l'activité ou le niveau de let-7 mlRNA dans une cellule endothéliale chez le sujet, ce qui permet de traiter une HTAP chez le sujet. Dans un autre aspect, l'invention concerne une méthode de traitement de l'HTAP chez un sujet, méthode comprenant l'administration au sujet d'un agent qui diminue l'activité ou le niveau d'un polypeptide de signalisation de TGFp endothélial ou d'un récepteur de peptide TGFp, ce qui permet de traiter une HTAP chez le sujet.
Patent CA-3148991-A1 (CA)
Inventor: VAN WYNGAARDEN CASE BRYANT
IPC: A61Q90/00
Filed: 2020-07-29
Abstract: A medical marking device can produce visible temporary marks, including at least one of indentations or colorations, in a specified pattern on skin or tissue of a patient. The marking device can include a body, such as a cap, that can removably attach over an end of a surgical marker. The body can include marking features, such as blades, optionally positioned at a longitudinal end of the body. The marking features can be pressed against the skin or tissue of the patient to form the visible temporary marks. The marking features can optionally be inked, optionally by the surgical marker, before the marks are formed. The marking features can optionally be distributed between a first subset, positioned generally along a line, and a second subset, positioned asymmetrically with respect to the line. An optional inclinometer can attach to the body to allow alignment to a horizontal direction.
Patent CA-3149814-A1 (CA)
Inventor: STREITNER CORINNA
IPC: C12N15/82
Filed: 2020-09-25
Abstract: The present invention relates to novel strategies for gradually decreasing the expression of genes by modifying the promoter sequence. Provided are methods for gradually decreasing the expression level of a nucleic acid molecule of interest in a cell, preferably in a plant cell, comprising the step of introducing at least one modification into a promoter sequence, wherein the modification disrupts a core promoter consensus sequence. Furthermore, the invention also provides methods for producing a cell or an organism, preferably a plant cell or a plant, having a decreased expression level of a nucleic acid molecule of interest. The invention also relates to a cell and an organism, preferably a plant cell and a plant, obtained by a method according to the invention.
Patent CA-3152436-A1 (CA)
Inventor: MOORE RANDY D
IPC: G16H50/20
Filed: 2020-09-25
Abstract: L'invention concerne un procédé permettant de déterminer un potentiel de rupture régionale (RRP) révélateur de l'état d'affaiblissement local d'un vaisseau sanguin sur la base de paramètres qui sont en corrélation avec la dilatation et l'affaiblissement local du vaisseau. Le procédé comprend les étapes consistant à : recevoir une pluralité d'images du vaisseau sanguin en un empilement multiphase. Un modèle géométrique de la lumière et de la paroi externe du vaisseau est généré et lissé pour obtenir respectivement une maille de volume et une maille de surface. Une distribution d'épaisseur de thrombus intraluminal (ILT), une déformation locale à chaque phase et une distribution de contrainte de paroi faisant état d'une contrainte principale maximale au niveau de la paroi externe sont déterminées. Des valeurs de débit sanguin dans la lumière sont obtenues et une distribution de contrainte de cisaillement de paroi indiquant des perturbations de cisaillement de paroi dans la lumière est calculée. Le RRP est déterminé sur la base de la distribution d'épaisseur d'ILT, de la contrainte de cisaillement de paroi et de la contrainte de paroi.
Patent CA-3153213-A1 (CA)
Inventor: GRANDAL MICHAEL MONRAD
IPC: C07K16/40
Filed: 2020-09-04
Abstract: La présente invention concerne des anticorps anti-CD73 et des procédés d'utilisation de ceux-ci dans le traitement de maladies et d'états liés à l'activité de CD73, par exemple le cancer.
Patent CA-3153417-A1 (CA)
Inventor: NAKAGAWA SATOSHI
IPC: H01M14/00
Filed: 2020-09-07
Abstract: The purpose of the present invention is to provide a system that enables stable supply of electric power, without being susceptible to influence from time periods or weather, and that exerts an excellent power generation output as compared with conventional stand-alone power systems. This system is provided with a first conductive part and a second conductive part, a medium, and a function part, wherein: the first conductive part and the function part are connected to each other, and the second conductive part and the function part are connected to each other; at least a portion of the first conductive part and the second conductive part are in contact with said medium; and the first conductive part and the second conductive part are not in contact with each other.
Patent CA-3153945-A1 (CA)
Title: Wireless patient monitoring compliance system
Inventor: NAGY PETER A
IPC: G06F17/00
Filed: 2020-09-11
Abstract: Methods and systems for close proximity monitoring of subjects, including in particular at-risk psychiatric subjects, where subjects have a tamper-resistant wearable device that signals an observer device, an observer records an observation of the subject, and the observer device emits an alert when the observer fails to record an observation during a predetermined time period.