baber/WOPTO huggingface dataset:
Patent CA-3004333-A1 (CA)
Inventor: MEI LIN
IPC: A61K39/395
Filed: 2010-10-21
Abstract: The present invention includes methods for the detection of neurotransmission or developmental disorders, including, but not limited to myasthenia gravis that is seronegative for autoantibodies to the acetylcholine receptor (AChR) and/or muscle specific tyrosine kinase (MuSK), the method including detecting autoantibodies that bind to LRP4, or an epitope thereof. Also, included are methods for the treatment of an individual suffering from a neurotransmission disorder, the method including detecting in a bodily fluid of the individual autoantibodies that bind to LRP4, or an epitope thereof, and administering to the patient an effective amount an immunosuppressant and/or another appropriate therapeutic modality. Also included are antibodies that bind to autoantibodies to LRP4 and kits for the detection of neurotransmission or developmental disorders.
Patent CA-3005192-A1 (CA)
Inventor: ZHANG HOUJI
IPC: C02F1/38
Filed: 2018-05-17
Abstract: A wastewater treatment system includes a settling tank, a three-phase separator, a settling basin, a primary lift pump, a multi-function processing water tank, a secondary lift pump, a rough processing unit, a fine processing unit, a polishing unit, an air compressor, an air tank and the pipe valves compatible therewith; the sludge slurry treatment system includes a blowdown tank, a slurry lift pump, an oil mud water separation device, a sludge slurry concentration or solidification device and the pipe valves compatible therewith. The process has strong adaptability to incoming water, short processing flow and desirable airtightness. It is not necessary to rinse and regenerate with acid and alkali solutions. Moreover, all the standards required are met. Dosing is not required during operation. A complete oil mud water separation and sludge concentration or solidification system in the blowdown tank is provided.
Patent CA-3006065-A1 (CA)
Inventor: ROPER TODD
IPC: E21B43/267
Filed: 2016-11-14
Abstract: Lightweight proppant particles are disclosed. The lightweight proppant particle can include a proppant particle having an apparent specific gravity of at least about 1.5 g/cc, a coating of a hydrophobic material formed on an outer surface of the proppant particle, and a coating of an amphiphilic material formed on an outer surface of the coating of the hydrophobic material.
Patent CA-3006375-A1 (CA)
Title: Poulie a reaction de couple pour broyeur a cone d'inertie
Inventor: FREDRIKSSON MAGNUS
IPC: B02C2/04
Filed: 2015-12-18
Abstract: La présente invention concerne une poulie à réaction de couple (42) pour un broyeur à cône d'inertie ayant un composant élastiquement déformable (77, 78) sensible à un changement de couple par l'intermédiaire de la transmission d'entraînement du broyeur dû à la rotation d'un poids déséquilibré (30) dans le broyeur.
Patent CA-3007877-A1 (CA)
Title: Preparations combinees de modulateurs de pkm2 et de hmgb1
Inventor: GDYNIA GEORG
IPC: A61K35/12
Filed: 2016-12-12
Abstract: La présente invention concerne une préparation combinée comprenant (i) un modulateur de l'activité pyruvate kinase M2 (PKM2), et (ii) un agent fournissant un polypeptide HMGB1 (high mobility group box 1) ou un dérivé de celui-ci. L'invention concerne également la préparation combinée précitée pour une utilisation à titre de médicament et dans le traitement d'une prolifération cellulaire inappropriée, de préférence dans le traitement du cancer. Un procédé permettant de déterminer si un patient souffrant d'une prolifération cellulaire inappropriée est éligible ou non à un traitement comprenant l'administration d'un modulateur de l'activité PKM2 à titre de seul inhibiteur de PKM2 et à des méthodes thérapeutiques apparentées est en outre décrit.
Patent CA-3008410-A1 (CA)
Title: Stackable grow pot system
Inventor: OLIVER JOEL
IPC: A01G9/029
Filed: 2018-06-14
Abstract: A stackable grow pot system including a plant pot having an inner volume, a plurality of side-walls, and a base including a selectively removeable disc. The selectively removeable disc is configured to be removed to allow plant roots to extend through an aperture. The plant pot is stackable. When stacked, the plant pot provides for volume expansion for growth of a plant and the plant roots through the aperture into a second-plant-pot. The device allows for quick and efficient transplanting.
Patent CA-3010214-A1 (CA)
Title: Utilisation du z-hfo-1,1,1,4,4,4-hexafluoro-2-butene dans des applications d'expansion a haute temperature
Inventor: WYSONG ERNEST BYRON
IPC: C08J9/14
Filed: 2017-01-18
Abstract: La présente invention concerne un procédé comprenant la réaction d'un polyisocyanate avec un composé à hydrogène actif en présence du Z-1,1,1,4,4,4-hexafluoro-2-butène à une température d'au moins 135 °F (57,2 °C) ou à une température de 135 °F (57,2 °C) à 150 °F (65,6 °C) afin d'obtenir un produit réactionnel expansé, la conductivité thermique du produit réactionnel expansé ne présentant aucun changement notable aux températures d'expansion situées dans cette plage.
Patent CA-3011945-A1 (CA)
Inventor: LUPI GIUSEPPE
IPC: B65H45/28
Filed: 2017-01-19
Abstract: Unité d'entrelacement, comprenant une paire de rouleaux (1, 2) placés côte à côte et contrarotatifs et pourvus de premier et second outils de pliage (3, 4; 5, 6) respectifs placés à une distance l'un de l'autre le long du développement circonférentiel des surfaces périphériques respectives de manière à fonctionner dans un point de tangence commun (Z) sur une succession de feuilles (7a, 7b) introduites entre les deux rouleaux, lesdits outils (3, 4; 5, 6) étant placés sur des secteurs de cylindre mobiles respectifs (8, 9, 10, 1 1) pour permettre leur positionnement espacés d'une distance réglable le long du développement circonférentiel d'un rouleau correspondant (1, 2), ladite unité d'intercalage comprenant des moyens (M1, M2, U) pour régler indépendamment la vitesse de rotation d'un ou de plusieurs desdits secteurs selon leur position angulaire afin de réduire ou d'augmenter la vitesse périphérique desdits secteurs par rapport à une vitesse d'introduction (Vm) desdites feuilles.
Patent CA-3013292-A1 (CA)
Inventor: NAKANO SEIJI
IPC: H01S5/02
Filed: 2016-02-22
Abstract: The art disclosed in the present description relates to: a laser light source device capable of suppressing a loss of light output from a semiconductor laser element, while ensuring the degree of freedom in disposition of a semiconductor laser element; and a method for manufacturing the laser light source device. A laser light source device relating to the present art is provided with a semiconductor laser element (2), and an optical element (3) that is provided on the optical axis of output light outputted from the semiconductor laser element (2). The optical element (3) separates, in the fast axis direction, a part of a luminous flux of the output light from the other part of the luminous flux, said output light having been outputted from the semiconductor laser element (2), and not having been separated in the fast axis direction.
Patent CA-3013494-A1 (CA)
Title: Water/crude oil removers based on alkylacrylic-carboxyalkylacrylic random copolymers of controlled molecular mass
Inventor: FLORES SANDOVAL CESAR ANDRES
IPC: C08F220/28
Filed: 2018-08-07
Abstract: New copolymers are provided for the removal of water and salts from crude oil, that is resilient to the acid stimulation operations of petroleum wells. These copolymers are combinations of an alkyl acrylate and a carboxyalkyl acrylate, having structural formula (2).   (see formula 2) These copolymers are synthesized by semi-continuous emulsion polymerization to ensure both the homogeneity of the different chains as well as the randomness of the monomers distribution.
Patent CA-3015200-A1 (CA)
Title: Systems and methods for resonance stabilization of microring resonator
Inventor: KNIGHTS ANDREW P
IPC: H04J14/02
Filed: 2018-08-22
Abstract: Systems and methods are provided for stabilizing the resonance properties of a microring resonator modulator. Intrinsic optical absorption within the p-n junction of a microring modulator resonator is employed as a feedback signal for thermally stabilizing the microring resonator modulator. In some example embodiments, the input optical power provided to a bus waveguide that is optically coupled to the microring resonator modulator is sufficiently low such that the photocurrent dependence on input power is predominantly linear in nature, thereby avoiding or reducing the effect of nonlinear absorption through two-photon absorption. The example embodiments described herein may be employed to achieve a fabrication process that is free of heterogeneous device integration, for example, avoiding the integration of germanium detectors with a silicon-based integrated optical circuit or the need to sacrifice a portion of the ring resonator circumference for the integration of an extrinsic defect-mediated photodetector, thus reducing complexity and manufacturing cost.
Patent CA-3015954-A1 (CA)
Title: Gripper actuating system in a food processing machine
Inventor: PRYOR GLEN F
IPC: B26D7/01
Filed: 2017-11-28
Abstract: A gripping system of a food processing machine includes a gripping device, an airflow sensing device, at least one processor, and at least one memory. The gripping device is moveable between an open configuration and a closed configuration. The airflow sensing device is configured to sense an airflow. The at least one processor is in electronic communication with the airflow sensing device. The at least one memory is in electronic communication with the at least one processor. The at least one memory comprises programming code for execution by the at least one processor. The programming code is configured to move the gripping device from the open configuration to the closed configuration when the airflow sensing device senses a change in the airflow.
Patent CA-3016456-A1 (CA)
Inventor: Johnson Evan Charles
IPC: F02M25/12
Filed: 2017-03-06
Abstract: Apparatuses, systems, and methods are disclosed to produce HHO gas in a pressure- resistant container for use in an internal combustion engine to increase fuel efficiency and/or reduce emissions, for example by introducing the HHO gas to one or more air intake ports of the engine.
Patent CA-3024536-A1 (CA)
Inventor: GRAY STEVEN
IPC: A61K31/713
Filed: 2017-06-13
Abstract: This invention relates to polynucleotides comprising a nucleotide sequence encoding a PPT1 polypeptide or a fragment thereof, vectors (viral or non-viral vectors) comprising the same, and methods of using the same for delivery of the open reading frame to a cell or a subject and to treat infantile neuronal lipofuscinosis (infantile Batten disease). The polynucleotides comprise an optimized CLN1 open reading frame.
Patent CA-3028496-A1 (CA)
Inventor: SUN YUANBO
IPC: G06Q20/40
Filed: 2017-06-07
Abstract: Provided are an offline payment method and device. The method comprises: when a third-party payment application receives an offline payment request of a corresponding target payment application, the third-party payment application obtains an identity authentication identifier of a user sending the request; when it is determined that the obtained identity authentication identifier is passed, the third-party payment application obtains an offline payment certificate granted by the target payment application to the user and stored in a terminal; and the third-party payment application provides the offline payment certificate to an office payment service party, so that the office payment service party requests, according to the offline payment certificate, the target payment application to process offline payment of the user. It is more convenient and securer when offline payment is carried out from a payment application among third-party payment applications integrated in a consumer terminal.
Patent CA-3028636-A1 (CA)
Title: Collaborative dataset consolidation via distributed computer networks
Inventor: Jacob Bryon Kristen
IPC: G06F17/00
Filed: 2017-06-16
Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and wired and wireless network communications to provide an interface between repositories of disparate datasets and computing machine-based entities that seek access to the datasets, and, more specifically, to a computing and data storage platform that facilitates consolidation of one or more datasets, whereby a collaborative data layer and associated logic facilitate, for example, efficient access to, and implementation of, collaborative datasets. In some examples, a method may include receiving data representing a query into a collaborative dataset consolidation system, identifying datasets relevant to the query, generating one or more queries to access disparate data repositories, and retrieving data representing query results. In some cases, one or more queries are applied (e.g., as a federated query) to atomized datasets stored in one or more atomized data stores, at least two of which may be different.
Patent CA-3028783-A1 (CA)
Title: Double roller massage device
Inventor: MORRIS STEPHEN THOMAS CAULTON
IPC: A61H15/00
Filed: 2019-01-03
Abstract: A massage device, comprising: a hollow cylindrical outer roller having a first texture formed on an outer surface thereof; and, a cylindrical inner roller having a second texture formed on an outer surface thereof and sized to fit concentrically within the hollow cylindrical outer roller; wherein the cylindrical inner roller is moveable between a first position within the hollow cylindrical outer roller and a second position outside of the hollow cylindrical outer roller.
Patent CA-3029138-A1 (CA)
Title: Composition pharmaceutique liquide de clonidine
Inventor: PATEL KAMLESH
IPC: A61K31/4168
Filed: 2017-06-12
Abstract: La présente invention concerne une composition pharmaceutique liquide appropriée pour une administration orale comprenant de la clonidine ou des sels pharmaceutiquement acceptables de celle-ci avec au moins un tampon et au moins un conservateur. La présente invention concerne également un procédé de préparation de ladite composition pharmaceutique liquide.
Patent CA-3030689-A1 (CA)
Inventor: DALTON JAMES T
IPC: A61P35/00
Filed: 2011-08-24
Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g., melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.  Compounds included in the invention include compound 55 of the following structure:  (see above formula).
Patent CA-3034745-A1 (CA)
Title: Profile pour meuble, systeme de profiles pour meuble et procede d'assemblage d'un meuble
Inventor: GONZALEZ JOSE LUIS
IPC: A47B95/04
Filed: 2017-05-16
Abstract: La présente invention concerne un profilé (10, 20) destiné à un meuble configuré structurellement afin d'établir une première position d'association (30) et une seconde position d'association (31) par rapport au meuble, permettant ainsi une grande flexibilité dans la fabrication et l'assemblage du profilé, ainsi que dans le système correspondant, et fournissant à l'utilisateur une possibilité d'options de finition faciles à appliquer.
Patent CA-3038615-A1 (CA)
Inventor: ROLLINGER ADRIEN BERNARD VINCENT
IPC: F01D5/18
Filed: 2017-09-28
Abstract: Aeronautical turbine blade (10) comprising pressure-face-side cavities and suction-face-side cavities extending radially, and at least one central cavity situated in the central part of the blade (10) and surrounded by pressure-face-side and suction-face-side cavities, the blade (10) also comprising cooling circuits, in which at least a first cooling circuit (1) comprises: a first (A) and a second (B) cavity communicating with one another at an internal radial end (14) and at an external radial end (16) of the blade (10), a third cavity (C) communicating with the second cavity (B) at the external radial end (16), a fourth cavity (D) communicating with the third cavity (C) at the internal radial end (14), the first (A) and the second (B) cavities are fed jointly with cold air via a common air intake at the internal radial end (14), where the air flows in a first sense in the radial direction, the first cavity (A) being a pressure-face-side cavity, the second cavity (B) being a central cavity, the third cavity (C) and the fourth cavity (D) being suction-face-side cavities.
Patent CA-3038696-A1 (CA)
Title: Chloroplaste ou particule lipidique accumulee enrichi(e) en un polypeptide de fusion de proteine de corps huileux et son procede de production dans des algues
Inventor: ALCANTARA JOENEL
IPC: C07K19/00
Filed: 2017-10-03
Abstract: La présente invention concerne la production de protéines recombinantes dans des cellules algales. En particulier, la présente invention concerne des procédés de production de polypeptides recombinants en association avec des particules lipidiques accumulées ou des chloroplastes. Les procédés comprennent la production du polypeptide recombinant en tant que polypeptide de fusion avec une protéine de corps huileux et la croissance des cellules algales dans des conditions non homéostatiques pour former des particules lipidiques accumulées au sein des cellules algales, les particules lipidiques algales contenant le polypeptide de fusion.
Patent CA-3038839-A1 (CA)
Title: Rationally-designed synthetic peptide shuttle agents for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell, uses thereof, methods and kits relating to same
Inventor: DEL'GUIDICE THOMAS
IPC: C07K14/00
Filed: 2017-10-11
Abstract: The present description relates to methods for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell. The methods involve contacting the cell with the polypeptide cargo in the presence of a peptide shuttle agent at a concentration sufficient to increase the polypeptide cargo's transduction efficiency. Also described here are parameters that may be used in the rational design of such synthetic peptide shuttle agents, peptide shuttle agents that satisfy one or more of these design parameters, as well as methods and compositions relating to the use of the synthetic peptide shuttle agents for delivery of a variety of polypeptide cargos (such as transcription factors, antibodies, CRISPR-associated nucleases and functional genome editing complexes) from an extracellular space to the cytosol and/or nucleus of target eukaryotic cells. Applications and targets for genome-editing NK cells for improved immunotherapy are also described.
Patent CA-3040122-A1 (CA)
Title: A leg sling
Inventor: LEE AMY
IPC: A63B23/04
Filed: 2019-04-12
Abstract: A leg sling for use on a lower limb has a waist belt configured to be secured around a user's waist. At least two connectors are attached to the waist belt. A pair of assistance lines made of a stretchable and resilient material are provided. Each of the assistance lines has a connector end attachable to one of the at least two connectors and a foot sling end. A foot sling is made of a flexible material. The foot sling has a foot support, a left connection and a right connection. The left connection is connectable to the foot sling end of one of the assistance lines and the right connection is connectable to the foot sling end of the other assistance line.
Patent CA-3040198-A1 (CA)
Inventor: KUSTER HANS-WERNER
IPC: E06B3/663
Filed: 2017-10-17
Abstract: L'invention concerne un vitrage isolant (100), notamment un triple vitrage isolant, comprenant : au moins un intercalaire (4) qui est formé de manière périphérique pour donner un cadre d'intercalaire (4') et délimite une zone interne (9), une première vitre externe (3a) disposée sur une première surface de contact (4.1) pour vitre du cadre d'intercalaire (4') et une deuxième vitre externe (3b) disposée sur une deuxième surface de contact (4.2) pour vitre du cadre d'intercalaire (4'), au moins une vitre centrale (2) qui est insérée dans au moins un intervalle (7) au moins d'un profilé de retenue (1), le profilé de retenue (1) étant formé de manière périphérie pour donner un cadre (1') de profilé de retenue, qui encadre la vitre centrale (2), et la vitre centrale (2) dotée du cadre (1') de profilés de retenue étant disposée à l'intérieur de la zone interne (9) du cadre d'intercalaire (4') et entre les vitres externes (3a, 3b).
Patent CA-3040500-A1 (CA)
Inventor: PEARCE TONY M
IPC: A47G9/02
Filed: 2017-10-18
Abstract: A bed linen comprises a single, continuous piece of fabric extending substantially completely across lateral dimensions of the bed linen and including elastomeric fibers and non-elastomeric fibers. The single, continuous piece of fabric is configured to stretch to at least 125 percent of an initial length thereof without damage thereto and to substantially return to the initial length thereof after being stretched. A bedding assembly and a method of forming a bedding assembly are also described.
Patent CA-3041475-A1 (CA)
Title: Nonlinear acoustic downhole pore pressure measurements
Inventor: GOODMAN HARVEY E
IPC: E21B47/06
Filed: 2017-03-26
Abstract: Apparatus (10) and methods for measurement of pore pressure in rock formations through a metal borehole casing (32) after a well is cased and cemented, are described. Such measurements may be accomplished by using the Dynamic Acoustic Elasticity (DAE) method for characterizing nonlinear parameters by perturbing a selected rock formation region with a High Amplitude, Low Frequency (HALF) acoustic strain wave, and probing this region using a Low Amplitude, High Frequency (LAHF) acoustic wave (18), (22). Time reversal techniques (36) may be employed for focusing acoustic energy into the formation in the vicinity of the pipe or open hole. The change in wave speed of the probe pulses as the HALF induced strain wave oscillation propagates through the formation, as a function of the induced strain, may be used to determine the nonlinear elastic parameters a, ß, d, and A of the pore pressure, from which the pore pressure may be determined in the region of the HALF wave.
Patent CA-3044929-A1 (CA)
Inventor: OSAKI YOSHIRO
IPC: A23L5/00
Filed: 2017-11-15
Abstract: L'invention concerne une capsule dure dans laquelle le dépôt d'un adjuvant de gélification dans un film de revêtement de capsule dure est amélioré. Dans la présente invention, le dépôt d'un adjuvant de gélification est régulé par l'ajout d'un disaccharide non réducteur ou d'un alcool disaccharidique non réducteur à un film de revêtement de capsule dure.
Patent CA-3050089-A1 (CA)
Title: Dental implant
Inventor: KIM HYUNG-WOO
IPC: A61C8/00
Filed: 2018-01-15
Abstract: A dental implant according to the present invention comprises: an elastic fastening leg for performing a function to fasten an abutment to a fixture by elastic bending in the direction of a central axis and the restoring force of elastic legs of the abutment; a non-fastening elastic support leg not involved in direct engagement of the abutment and the fixture; and a first corresponding fastening part formed on an outer circumferential surface of the elastic fastening leg of the abutment, and formed by a fastening protrusion complementarily joined to a first fastening part formed on the inner surface of the shaft hole of the fixture, wherein in the state where the abutment is engaged in the fixture by the complementary engagement of the first fastening part and the first corresponding fastening part, a function to prevent rotation of the abutment against the fixture is performed at a rotational force of less than a predetermined level, while at a rotational force of more than a predetermined level, the elastic fastening leg of the abutment is elastically bent in an inner diameter direction, and the abutment is rotated in a circumferential direction so that the fastening protrusion of the first corresponding fastening part is separated from the fastening groove of the first fastening part, thereby separating the fixture from the abutment.