baber/WOPTO huggingface dataset:
Patent NZ-503622-A (NZ)
Title: Composition which have inhibitory effects of polyanionic substances on replication of herpes simplex virus (HSV) and other viruses such as human immunodeficiency virus (HIV)
Inventor: FOONG WAI-CHOONG
IPC: A61K36/53
Filed: 1998-09-23
Abstract: A composition provided by extraction and purification from the spikes of Prunella vulgaris. The compositions are effective agents for treatment of the cytopathogenic effects of an enveloped virus in mammals. In the preferred embodiment, there are provided methods for the treatment of the cytopathogenic effects of an enveloped virus and related indications in mammals, employing the compositions as the active agent. Further described are that the compositions are effective agents for the treatment of the cytopathogenic effects of an enveloped virus in mammals exposed to immunosuppressive regimens. The compositions also provide an effective agent for protecting mammals from reactivated viral infection during or following treatment with chemotherapeutic agents. Also provided are methods for preparing extracts of Prunella vulgaris having antiviral action and the formulations containing such extracts. The method for purification and characterisation of the active fraction from Prunella vulgaris useful for treating the cytopathogenic effects of an enveloped virus in a mammal is described. The compositions are effective agents for the prophylaxis and therapy in mammals of diseases caused by enveloped viruses.
Patent NZ-504372-A (NZ)
Title: Process to produce N-[3-fluoro-4(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinones
Inventor: PEARLMAN BRUCE A
IPC: C07D487/04
Filed: 1998-10-13
Abstract: Disclosed is a number of intermediates such as the (S)-secondary alcohol of formula (VIIIA) X2-CH2-C*H(OH)-CH2-NH-CO-RN and processes for production of pharmacologically useful oxazolidinones. RN is C1-C5 alkyl, and X2 is -Cl, -Br, p-toluenesulfonyl or m-nitrophenylsulfonyl.
Patent NZ-506001-A (NZ)
Title: Multiway valve
Inventor: FONDSE JAN HENDRIK
IPC: F16K11/065
Filed: 1999-01-08
Abstract: A multiway valve, comprising a chamber into which at least four feed or discharge ducts (61, 68, 92, 96) open out, the state of being open or closed of at least three of the ducts being affected by the positioning of a member (91) which is, moveable in directions of movement substantially perpendicular with respect to one another, accommodated inside the chamber, and which member can be made to interact in a sealing manner with one or more duct openings, and control means (L1-4) for moving the member inside the housing.
Patent NZ-506767-A (NZ)
Title: Device and method for feeding a constant amount of powder body
Inventor: MATSUGI HIDEO
IPC: A61M15/00
Filed: 2000-01-14
Abstract: A powdered medicine multi-dose administering device has a medicine container unit (5b) for containing a unit-dose of medicine under the lower surface of the medicine storage chamber (5a) storing the medicine in a multi-dose amount. A medicine guiding unit (2) moves between a filling position and an administering position while maintaining a contact with the bottom surface. At the filling position, the medicine container unit is opened to the medicine storage chamber and is filled with the medicine. As the medicine container unit moves from the filling position to the administering position, the powdered medicine in the medicine container unit is swept and metered. At the administering position, the medicine in the medicine container unit is injected by the action of the pump unit (3) through a filter (6) and a pipe (2g, 2d, 2c).
Patent NZ-508052-A (NZ)
Title: Programmable controller
Inventor: WARD DEREK
IPC: G06F17/50
Filed: 2000-11-09
Abstract: A programmable controller includes at least one user input interface (11) and an input register (12) for connection to process plant and /or machinery to provide sampled and stored input data in digital form. Also, there is at least one user output interface (15) and an output register (14) for connection to process plant and/or machinery to receive and store output data in digital form. Programmable logic hardware (13) is also included, having a plurality of basic logic elements and electrically configurable interconnections. These interconnections are configurable to interconnect the logic elements as a user control program circuit and to connect the user control program circuit to said input and output interfaces. A program loading means is provided to enable the user to configure the programmable logic hardware as a circuit implementing a user control program prior to initiating control of the associated process plant and/or machinery.
Patent NZ-510258-A (NZ)
Title: Method and apparatus for computed relevance messaging
Inventor: HINDAWI DAVID SALIM
IPC: G06Q10/10
Filed: 1999-08-27
Abstract: The method disclosed herein enables a collection of computers and associated communications infrastructure to offer a new communications process which allows information providers to broadcast information to a population of information consumers. The information may be targeted to those consumers who have a precisely formulated need for the information. This targeting may be based on information that is inaccessible to other communications protocols. The targeting also includes a time element. Information can be brought to the attention of the consumer precisely when it has become applicable, which may occur immediately upon receipt of the message, but may also occur long after the message arrives. The communications process may operate without intruding on consumers who do not exhibit the precisely specified need for the information, and it may operate without compromising the security or privacy of the consumers who participate.
Patent NZ-511136-A (NZ)
Title: Database system
Inventor: SHIMIZU ISAO
IPC: G06F17/30
Filed: 2000-08-28
Abstract: A database system has a simplified table structure and minimal program content. Category identification information on the categories of the objects to be registered, the names of items representing the attributes and/or the functions, and the attributes (item data attributes) that expression data for expressing the substantial contents of the item names has are registered in the data cells in units of a line in a data property table (21). Category identification information, the names of titles, and the substantial contents relating the items are registered in the data cells in units of a line in a main data table (22). The item names of the table (21) and the substantial contents of the table (22) are correlated with each other through the cell number. A database management system (10) generates methods by using the line data in the table (21) as messages when data is inputted/stored/retrieved/outputted.
Patent NZ-512863-A (NZ)
Title: Mounting system for modular panels used in a screen deck
Inventor: MOSER ROBERT E
IPC: F16B19/10
Filed: 2000-01-14
Abstract: Screen deck assembly 10 has a locking system for retaining a plurality of modular screen panels 20 in such a manner that they can be individually replaced, if desired. The system includes sets of abutting retainer bars 18 which each have half of a generally cylindrical opening 28 which is adapted to receive generally cylindrical sleeve members 30. The sleeve members extend through the retainer bars and also through openings 14 in underlying support frame members 12. Locking pins 32 inserted into the sleeve members expand the lower portions of the sleeve members to lock the retainer bars relative to the support members. Sideways separation of the abutting retainer bars is prevented by downwardly extending continuous annular ring portions 72 on the sleeve members which are seated in complementary semi-circular grooves 61 formed in each of the abutting retainer bars. The sleeve members can be made in a range of sizes with varying outer diameters at their lower ends to accommodate wear or varying dimensions of the openings in the support frame members.
Patent NZ-514692-A (NZ)
Title: Disposable safety syringe
Inventor: D USSEL BERNARD
IPC: A61M5/31
Filed: 2000-04-13
Abstract: The invention concerns a disposable safety syringe comprising a cylindrical pump body (1) extended by a needle (3) integral with said body and comprising a plunger (2). Said pump body (1) includes a proximal part (4) provided with the needle (3) and a distal part (5) with a larger diameter comprising the plunger (2); the proximal part (4) includes sealing means (6, 7, 9). The invention is applicable in the field of medicine.
Patent NZ-514868-A (NZ)
Title: Data processing system using a dual monitor and controlling method of network system thereby
Inventor: LEE EUN SEOG
IPC: G06F17/40
Filed: 2001-02-20
Abstract: Disclosed is a data processing system using a dual monitor, on which separate contents are displayed respectively, as a display device. The data processing system includes: a memory providing a data processing area using programs; an input device for inputting data; a first VGA generating screen data for a result processed by programs; a second VGA generating screen data for a result processed by programs and different from the contents displayed by the first VGA; a processor processing data input through the input device using the memory and outputting the processed result through the first and second VGAs; a first monitor for displaying screen data from the first VGA; and a second monitor for displaying screen data form the second VGA.
Patent NZ-516118-A (NZ)
Title: Packaging or bottles for fluorochrome sensitive reagents specifically around 400-600 nm wavelength to protect the reagent from degradation to light
Inventor: DAZIANO JEAN-PIERRE
IPC: B65D81/30
Filed: 2001-12-13
Abstract: Packaging comprising a fluorochrome sensitive to visible light placed in a bottle of which at least the side walls form an effective screen against light spectrum radiation between 200-900 nm and a process for protecting fluorochromes sensitive to visible light during storage, in which the fluorochromes are placed in a bottle of which at least the side walls form an effective screen against light spectrum radiation between 200 and 900 nm, and a method for packaging of fluorochrome based reagents for cytometry is disclosed.
Patent NZ-517304-A (NZ)
Title: Stirrups
Inventor: MORGANTE ADRIAN ANTHONY
IPC: B68C3/00
Filed: 2000-07-17
Abstract: An accessory (10) for a stirrup iron (12) having a stirrup bottom (14) and a stirrup top (16), the stirrup top having an upper portion (18) to which a stirrup leather is attached, in use, and a pair of opposed side portions (22), the accessory dimensioned to be receivable within the stirrup opening (46) and including a receptacle (24) of a flexible material with a cover member (28) and a floor member (30) that defines a region (26) in which a boot or shoe of a rider is receivable, and at least one upper strap (32) that extends from the cover member to be engageable with the stirrup top, and at least one lower strap (34) or two side straps (52) that extend from the floor member or sides of the cover member respectively and engageable with the bottom or sides of the stirrup respectively, and a fastening arrangement (36) that is positioned on at least the straps to permit the straps and thus the receptacle to be releasably fastened to the stirrup iron, so that in use forward movement of the rider's boot, relative to the stirrup iron, is substantially checked, the fastening arrangement being adjustable so that the position of the receptacle relative to the stirrup iron can be adjusted, the straps being of sufficient length to go over the respective part of the stirrup to fasten to the receptacle, their adjustment resulting in adjustment of the toe position of the receptacle.
Patent NZ-517783-A (NZ)
Title: Method for the detection of oxidized forms of soluble guanylate cyclase and a method for screening post activators of soluble guanylate cyclase with oxidized haem iron
Inventor: SCHINDLER URSULA
IPC: C12Q1/527
Filed: 2000-08-19
Abstract: A method for detecting a soluble guanylate cyclase where the iron of the heme is on the trivalent oxidation state comprises; providing a soluble guanylate cyclase and at least one chemical compound which stimulates the activity of the soluble guanylate cyclase when the iron of the heme is in the trivalent state selected from 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one; then incubating the soluble cyclase with the chemical compound and determining the activity of the soluble guanylate cyclase after the incubation. Also described are methods of finding a chemical compound that stimulates the activity of a soluble guanylate cyclase and methods of determining the oxidation state of a soluble guanylate cyclase in a biological sample and a luminometric assay for detecting a soluble guanylate cyclase.
Patent NZ-518406-A (NZ)
Title: Stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride useful in treating cancer
Inventor: CONNELL RICHARD D
IPC: A61K38/46
Filed: 2000-11-09
Abstract: A homogeneous crystalline polymorph of the hydrochloride salt of N- (3-ethynylphenyl)-6,7-bis(2 methoxyethoxy)-4-quinazolinamine designated the B polymorph that exhibits an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2-theta at approximately 6.26, 12.48, 13.39, 16.96, 20.20, 21.10, 22.98, 24.46, 25.14 and 26. 91. The compound is used to treat abnormal cell growth such as cancer and atherosclerosis. N- (3-ethynylphenyl)-6,7-bis(2 methoxyethoxy)-4-quinazolinamine in anhydrous from or hydrate form is used in the manufacture of a medicament to treat non small cell lung cancer, pediatric malignancies, cervical and other tumours caused or promoted by human papilloma virus, endometrial cancer, Barrett's esophagus (pre malignant syndrome) or neoplastic cutaneous diseases.
Patent NZ-522500-A (NZ)
Title: Thermostable reverse transcriptases and uses thereof
Inventor: SMITH MICHAEL D
IPC: C12N1/21
Filed: 2001-05-25
Abstract: The application is related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically disclosed are reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity. Methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions are also disclosed as are the nucleic acid molecules produced by these methods.
Patent NZ-524033-A (NZ)
Title: Compositions and methods for detecting target microorganisms in a sample
Inventor: TOWNSEND DAVID
IPC: G01N33/48
Filed: 2001-08-27
Abstract: A composition for detecting a target microorganism in a sample, comprising a conditionally detectable marker, wherein said marker is capable of providing a detectable signal when in contact with a viable microorganism, and a substrate for an enzyme that is substantially absent from the target microorganism. Said target microorganism is selected from bacteria, yeast, mold, fungi, protozoa or viruses. Also disclosed is a medium for detecting viable microorganisms in a sample comprising: a) a substrate for an aminopeptidase; b) a conditionally detectable marker, wherein said marker is capable of providing a detectable signal when in contact with a viable moicroorganism; c) a signal moiety linked to the substrate, said moiety providing a detectable signal when cleaved by said aminopeptidase from said microorganism; d) a growth supporting medium for target or non-target microorganism. and a method for using said medium for detecting viable microorganisms in a sample, comprising: a) providing said medium; b) inoculating said medium with the sample to be tested; c) incubating the inoculated medium under suitable conditions wherein the enzyme substrate is capable of being acted upon by an enzyme from substantially all non-target microorganisms to produce a detectable signal; and d) comparing the difference between the signal generated by conditionally detectable marker and the enzyme substrate, whereby the absence or decrease in a detectable signal indicates the presence of target microorganisms in the sample.
Patent NZ-528340-A (NZ)
Title: Spray delivery of cells
Inventor: MARSHALL JULIAN M
IPC: A61K35/36
Filed: 1999-12-02
Abstract: Provided is a method of adhering cells to a target surface which is a tissue surface of a non-human mammal or such a tissue surface coated with a biodegradable polymer sheet, comprising: coating the target surface with a mixture of a first component comprising a non-polymeric fibrin-related protein and a second component effective for converting the fibrin-related protein to fibrin polymer; and spraying a suspension of the cells onto the coated target surface, wherein the mixed two components have formed a fibrin polymer with a tack effective to adhere the cells. (62) Divided out of 512220
Patent NZ-528704-A (NZ)
Title: Novel PRO717 polypeptides and nucleic acids encoding a 12 transmembrane polypeptide
Inventor: WOOD WILLIAM I
IPC: A61K39/395
Filed: 1999-03-08
Abstract: An isolated nucleic acid having at least 80% sequence identity to a nucleotide sequence that encodes a polypeptide designated PRO717 comprising the amino acid sequence SEQ ID NO:420. Preferably the nucleic acid comprises the sequence of SEQ ID NO:419 or is that deposited under accession number ATCC 209814. Vectors, isolated host cells, processes for preparing the polypeptide and antibodies are also described. (62) Divided out of 507435
Patent NZ-528906-A (NZ)
Title: Compounds and methods for the inhibition of the expression of VCAM-1
Inventor: SOMERS PATRICIA K
IPC: A01N37/02
Filed: 1998-05-14
Abstract: Compounds of formula (I) that are suitable for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases are disclosed, wherein the variables shown in formula (I) are as defined in the specification.
Patent NZ-534296-A (NZ)
Title: Chemical compounds
Inventor: ALCARAZ LILIAN
IPC: A61K31/53
Filed: 2003-02-17
Abstract: Compounds of formula (I) wherein: X is CH2, O, S(O)2 or NR10; Y is a bond, CH2, NR35, CH2NH, CH2NHC(O), CH(OH), CH(NHCOR33), CH(NHSO2R34), CH2O or CH2S; Z is C(O), or when Y is a bond Z can also be S(O)2; R1 is optionally substituted aryl, optionally substituted heterocyclyl or C4-6 cycloalkyl fused to a benzene ring; and R2, R3, R4, R5, R6, R7 and R8, R9, R10, R32, R33, R34 and R35 are as defined.
Patent NZ-535617-A (NZ)
Title: Piperazinyl- or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase
Inventor: LEHR PHILIPP
IPC: A61P35/00
Filed: 2003-03-27
Abstract: A piperazinyl-or piperidinylamine-sulfamic acid amide compound of formula one which are inhibitors of steroid sulfatase as described. These compounds can be used in the manufacture of a medicament for the treatment of diseases, in particular acne.
Patent NZ-539562-A (NZ)
Title: Compositions and methods for transdermal oxybutynin therapy
Inventor: SANDERS STEVEN W
IPC: A61K47/10
Filed: 2003-10-31
Abstract: Disclosed is an article of manufacture for transdermal application consisting of a backing film and an adhesive matrix wherein the adhesive matrix comprises a mixture of oxybutynin, a polymeric adhesive and a permeation enhancer and wherein the transdermal matrix patch is capable of delivering 3mg per day of oxybutynin and providing a plasma area under the curve (AUC) ratio of oxybutynin to oxybutynin metabolite of about 0.8:1 to about 1.5:1 and a plasma concentration of oxybutynin metabolite of about 1.0ng/ml to 3 ng/ml based upon a single application of the article for 4 days.
Patent NZ-539950-A (NZ)
Title: Aminoalkoxyindoles as 5-HT6-receptor ligands for the treatment of CNS-disorders
Inventor: ZHAO SHU-HAI
IPC: A61K31/55
Filed: 2003-11-27
Abstract: Disclosed is an aminoalkoxyindole compound of formula I wherein m is from 0 to 3; n is from 0 to 2; R2 is optionally substituted aryl or optionally substituted heteroaryl; R3 is hydrogen or alkyl; p is 2 or 3 and all other substituents are as described in the specification. Also provided is the method for production, compositions comprising, and the use of compounds of formula I for the manufacture of medicaments for the treatment of 5-HT6 mediated diseases.
Patent NZ-540635-A (NZ)
Title: Transmitting and receiving device for controlling tools in an oil well
Inventor: LE BRIERE BRUNO
IPC: E21B47/12
Filed: 2003-11-28
Abstract: A data transmission device and an underground installation 1 that includes the device are disclosed. The device is intended for use in an installation 1 made up of a cavity 13 which extends from the surface 17 of the ground and which is equipped with at least one tubular electrically-conductive element 21, 25. The device includes a smooth, electrically-conductive, single-strand cable 3 which is used to support an assembly 5 for carrying out work and/or taking measurements, the cable having a tensile strength of greater than 3 kN and being located in the tubular element 21, 25. The surface of the cable 3 is electrically isolated at least partially from the tubular element 21, 25. The device further includes means 9, 11 of transmitting and receiving an electric and/or electromagnetic signal, which are located close to the surface 17 and in the cavity 13 and which are connected electrically to (i) the cable 3 and (ii) to the tubular element 21, 25 and/or the soil formation 19. The invention can be used to transmit data and to control tools in an oil well.
Patent NZ-543658-A (NZ)
Title: Pollen polymix plant breeding method utilizing molecular pedigree analysis
Inventor: LAMBETH CLEMENTS C
Filed: 2001-07-12
Abstract: Disclosed is a method of evaluating plant progeny resulting from a pollen polymix cross comprising: (a) evaluating progeny plants grown from a plurality of progeny seed lots obtained from a pollen polymix crossed to a plurality of parental plants using objective criteria to obtain a phenotype score; (b) selecting a subset of candidate plants from the progeny plants evaluated in step (a) based upon the phenotype score; (c) determining the pedigree of the candidate progeny plants selected in step (b) using molecular parental analysis; (d) estimating the breeding value of the candidate progeny plants using pedigree and at least one plant phenotype; and (e) selecting elite plants from within the candidate progeny plants for use in a next 15 generation of plant breeding based upon the breeding value.
Patent NZ-545570-A (NZ)
Title: Amino acid prodrugs
Inventor: CHANDRAN V RAVI
IPC: A61K/
Filed: 2004-07-29
Abstract: Provided is a drug-conjugate product obtained by reacting the drug with an alpha-L- amino acid selected from L-Proline and L-Hydroxyproline under conditions effective to form a compound having a covalent bond between the drug and the alpha-L-amino acid, wherein the drug is selected from a list of specified drugs (including ibuprofen and aspirin), and characterized in that said drug-conjugate product provides for an enhanced therapeutic quality of the drug, the enhanced therapeutic quality being selected from the group consisting of: (a) improved taste or smell, (b) desired octanol/water partition coefficient, (c) improved stability, (d) enhanced penetration of blood-brain barrier, (e) elimination of first pass effect in the liver, (f) reduction of intero-hepatic recirculation, (g) painless injection with parental formulation, (h) improved bioavailability, (i) improved changes in the rate of absorption, (j) reduced side effects, (k) dose proportionality, (l) selective hydrolysis at site of action, (m) controlled release properties, (n) targeted drug delivery, (o) reduction in toxicity, (p) reduced dose, (q) alteration of metabolic pathway to deliver more drug at site of action, (r) increased solubility in aqueous solution and (s) enhanced efficacy.