baber/WOPTO huggingface dataset:
Patent DE-60129926-T2 (DE)
Inventor: VASIOS GEORGE
IPC: A61K45/00
Filed: 2001-01-22
Granted: 2008-06-19
Abstract: The role of the JAK/STAT signal transduction pathway cellular mechanisms that lead to the onset and progression of degenerative joint diseases or disorders such as osteoarthritis (OA) is disclosed. Certain known effective OA therapeutics such as hymenialdisine, debromohymenialdisine, and its variants and derivatives are shown to function as JAK3-specific inhibitors, which downregulate steady state mRNA levels of key cellular components involved in cartilage degradation. Another JAK3-specific inhibitor, not previously known as an OA therapeutic, is shown to downregulate steady state mRNA levels of various cellular components involved in cartilage degradation in a manner identical to that of the known OA therapeutics.
Patent DE-60131464-T2 (DE)
Inventor: QUIRK STEPHEN
IPC: A61K31/12
Filed: 2001-12-21
Granted: 2008-02-28
Abstract: The present invention provides compounds that are effective in treating disorders caused by the enzymatic activity of matrix metalloproteinases. These disorders include, but are not limited to, rheumatoid arthritis, osteoarthritis, periodontal disease, aberrant angiogenesis, tumor invasion and metastasis, corneal ulceration, and in complications of diabetes. The present invention is also is useful for treating wounds.
Patent DE-60200137-T2 (DE)
Inventor: JARD ALEXANDRE
IPC: H04B1/707
Filed: 2002-05-30
Granted: 2004-09-02
Abstract: A spread spectrum receiver for mobile telecommunications processes matched filter (4) output eigen vectors for channel (5) estimation using subtraction of the estimated eigen vectors for a more powerful channel from the estimated vectors for a weaker channel.
Patent DE-60219256-T2 (DE)
Inventor: COENRAADTS JACOBUS WILLEM KARE
IPC: A47J43/14
Filed: 2002-09-11
Granted: 2008-01-03
Abstract: The invention relates to a separation device for separating egg whites and egg yolks of eggs from which the shell has been removed, comprising at least one product trough (2) for egg white, one detection system (3) comprising a light source (4) and a light sensor (5) for the detection of contamination in the egg white in the product trough and a valve (7), which in reaction to the detection system in a first position (7') guides contaminated egg white to a discharge trough (8) and in a second position (7") guides non-contaminated egg white to a collecting trough (9). For every product trough (2) the detection system is provided with a light source (4) capable of emitting visible light, and the light sensor (5) is capable of detecting light coming from the product in the product trough (2). <IMAGE>
Patent DE-60220259-T2 (DE)
Inventor: COLAS NOBLECOURT CHRISTOPHE CA
IPC: H04N5/445
Filed: 2002-03-21
Granted: 2008-01-17
Abstract: The application describes a method of referencing content in an application. The method comprises, for a content element, creating a reference to the content element and associating that reference with the content element. This enables the content (for example, text or images) to be dissociated from other features related to content; for example, its presentation on the screen. In this way, control over presentation may be achieved separately from control of the content itself. In an example, a Content Provider 402 provides referenced content to an Operator 404. A Programme Provider 400 sends referenced scenarios to the Operator 404. The Operator 404 resolves the reference and sends data for broadcast by the Broadcaster 406. <IMAGE>
Patent DE-60222247-T2 (DE)
Inventor: GABERT JEAN
IPC: C12Q1/6851
Filed: 2002-03-15
Granted: 2008-05-08
Abstract: In a calibrant (A) that comprises a selected nucleic acid sequence (I), same as the sequence to be determined, inserted into a vector, the new feature is that the calibrant is linear. Independent claims are also included for the following: (1) method for preparing (A); (2) kit for measuring (I) comprising a set of dilutions of (A); (3) method for preparing the kit of (b); and (4) method for quantifying (I) in a sample.
Patent DE-60304505-T2 (DE)
Inventor: HU YONGQI
IPC: C25F3/30
Filed: 2003-05-02
Granted: 2006-09-07
Abstract: An article of manufacture, method, and apparatus are provided for planarizing a substrate surface. In one aspect, an article of manufacture is provided for polishing a substrate including a polishing article (205) having a body comprising at least a portion (310) of fibers coated with a conductive material, conductive fillers, or combinations thereof, and adapted to polish the substrate. In another aspect, a polishing article includes a body having a surface adapted to polish the substrate and at least one conductive element embedded in the polishing surface, the conductive element comprising dielectric or conductive fibers coated with a conductive material, conductive fillers, or combinations thereof. The conductive element may have a contact surface that extends beyond a plane defined by the polishing surface. A plurality of perforations (546) and a plurality of grooves (542) may be formed in the articles to facilitate flow of material through and around the polishing article. <IMAGE>
Patent DE-60306385-T2 (DE)
Inventor: WINQVIST PONTUS
IPC: A61F13/15
Filed: 2003-10-27
Granted: 2006-11-16
Abstract: An absorbent diaper (1) has a topsheet (5) and a backsheet (6) and an absorbent core (7). The diaper also has a rear waist portion (4), and a front waist portion (2), each having an upper edge respectively (8,9). The diaper further has a disposal tape (14) which is attached to both the topsheet (5) and the backsheet (6) across and around an upper edge (8, 9). One of the attachments (17) is releasable. The disposal tape (14) may be used as a means for maintaining the diaper in a rolled or folded configuration for disposal, while before being used for disposal it covers an upper edge (8, 9) of the diaper, providing a comfortable upper edge for the wearer. <IMAGE>
Patent DE-60306587-T2 (DE)
Inventor: SMITH DANIEL ROBIN
IPC: B21J15/06
Filed: 2003-07-12
Granted: 2007-07-05
Abstract: There is provided a blind fastener setting tool (12) which has a front end face (218) against which a blind fastener (14) is held during a conventional setting operation and which further has a piezo-electric thin film load measuring device (222) mounted on this front face so as to be disposed and compressed between the front face (218) and a flange (122) of the fastener (14) during the setting operation so as to record a low voltage electrical signal indicative of the load being exerted thereon. <??>There is further provided a method of measuring such load during the setting of a blind fastener by positioning a piezo-electric thin film load measuring device between a setting tool and a fastener and subsequently measuring a low voltage signal created as a result of deformation of the piezo-electric thin film during the setting operation and analysing this signal as indicative of the load exerted on the fastener. <IMAGE>
Patent DE-60307033-T2 (DE)
Inventor: NORDEEN CRAIG A
IPC: F02K7/02
Filed: 2003-12-24
Granted: 2006-12-21
Abstract: Distributed initiation (e.g., multipoint or continuous) is utilized to obtain constant volume-like combustion performance in a pulse combustion device (20) in the absence of detonation. A number of such devices (20) may be utilized as turbine engine combustors. The device comprises, in one embodiment, a tube (22) having a valve (30) for admitting gas to the tube, and a plurality of igniters (32) spaced along the tube. <IMAGE>
Patent DE-60314407-T2 (DE)
Inventor: NATTKEMPER DIETER
IPC: H04L12/10
Filed: 2003-04-29
Granted: 2008-02-21
Abstract: A system for managing power from a power source for at least one line powered network element in an access network is provided. The system includes a power manager that establishes at least one power criterion for the at least one network element. Further, the system includes a power controller that is responsive to the power manager. The power controller and the power manager communicate to manage operation of the at least one network element based on the at least one power criterion.
Patent DE-60318075-T2 (DE)
Inventor: ARCHER JOHN WILLIAM
IPC: H01Q21/00
Filed: 2003-07-11
Granted: 2009-01-15
Abstract: A method and apparatus are disclosed for forming an image from millimetre waves. A field of view scanned using two geometrically orthogonal, intersecting copolarized fan beams (110, 120) to receive millimetre wave radiation. The received millimetre wave radiation from said fan beams are then cross-correlated (250, 650). Also, a method and antenna (400, 610) for receiving millimetre wave radiation are disclosed. The antenna includes first and second fan beam antennas (410, 420) for receiving millimetre wave radiation and a filter (430, 440) for rotating polarization of incident millimetre wave radiation through 90 degrees received by the second fan beam antenna (410). The respective first and second beams (110, 120) intersect and are co-polarized and geometrically orthogonal to each other. Still further, a millimetre wave imaging system (600) and method are also disclosed, which utilise an antenna (610) for receiving millimetre wave radiation, process the received millimetre wave radiation from the antenna (610), and build up the image (682) using a filtered, cross-correlated signal.
Patent DE-68904483-T2 (DE)
Inventor: STAINMESSE SERGE
IPC: A61K9/51
Filed: 1989-06-28
Granted: 1993-05-19
Abstract: The process is characterised according to the invention in that: (1) a liquid phase consisting essentially of a solution of the protein and optionally of a biologically active substance in water or in an aqueous mixture is prepared at a temperature below the coagulation temperature of the protein, and to which one or more surfactants may be added, (2) a second liquid phase consisting essentially of water or an aqueous mixture is prepared at a temperature above the coagulation temperature of the protein, and which can contain a biologically active substance and to which one or more surfactants may be added, (3) one of the liquid phases obtained under (1) or (2) is added with moderate agitation to the other under pH conditions remote from the isoelectric point of the protein, so as to obtain virtually instantaneously a colloidal suspension of nanoparticles of the protein, and where appropriate, of the biologically active substance, and (4) if so desired, all or part of the water or of the aqueous mixture is removed so as to obtain a colloidal suspension having the desired concentration of nanoparticles or to obtain a powder of nanoparticles. Applications: biochemistry, pharmacy, medicine, cosmetics.
Patent DE-68922980-T2 (DE)
Inventor: HITA DE LA TORRE CARLOS
IPC: H04L5/16
Filed: 1989-12-27
Granted: 1995-12-07
Abstract: This system is applicable to channels that use packet, frame or message protocols, for which a half-duplex communications controller (1) is connected to a multiplexer (2) which, in turn, is connected to two different clock circuits (3, 4), to provide the controller with a working frequency in the reception mode and another working frequency in the transmission mode. The system includes a buffer memory (11) in which the data to be transmitted are stored at a rate much higher than that at which they are transmitted to the line, these data being transferred to a serializer (15) which delivers the data to the line (8) through a transmission interface (16) at the line transmission rate. The system is normally in the reception mode and changes from this state when the transmission operation is desired, after having verified that no reception is taking place.
Patent DE-68925494-T2 (DE)
Inventor: DAWSON MICHAEL JOHN
IPC: A61K31/335
Filed: 1989-05-09
Granted: 1996-11-07
Abstract: Compounds of formula (1) <CHEM>  and salts thereof, wherein  R<1> represents a methyl, ethyl or isopropyl group;  Y<1> is -CH2-, Y<2> is -CH- and X represents <CHEM> where R<2> represents a hydrogen atom or a group OR<8> (where OR<8> is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R<3> represents a hydrogen atom, or R<2> and R<3> together with the carbon atom to which they are attached represent >C=0, >C=CH2 or >C=NOR<9> (where R<9> represents a hydrogen atom, a C1-8 alkyl group or a C3-8 alkenyl group) and the group >C=NOR<9> is in the E configuration] or -Y<1>-X-Y<2>- represents -CH=CH-CH- or -CH2-CH=C-; R<4> represents a group OR<8> as defined above and R<5> represents a hydrogen atom, or R<4> and R<5> together with the carbon atom to which they are attached represent >C=0 or >C=NOR<9a> (where R<9a> is as defined above for R<9>); R<6> represents a hydrogen atom and R represents -CH2OH, -CHO, -CO2H or a carboxylic acid ester or amide group; or R<6> represents a hydroxyl group and R represents a methyl group; and R<7> represents a hydrogen atom or when R represents a group -CH2OH then R<7> may also represent a hydroxyl group. The compounds may be used to control nematode, acarine, insect or other pests.
Patent DE-69001182-T2 (DE)
Inventor: GREGOIRE GABRIEL
IPC: F16D55/2265
Filed: 1990-01-03
Granted: 1993-07-08
Abstract: A disc brake (10) for a motor vehicle comprising a stationary support for mounting on the motor vehicle; a caliper (12) slidably mounted on the stationary support; at least one pin (14) fixed at one end (22) to either the stationary support or the caliper and slidably positioned in an axial bore (16) in the other for slidably mounting the caliper, with the other end (30) of the pin being positioned at or adjacent one end (32) of the axial bore; and a cap seal (36,36 min ) sealing the said one end of the axial bore, the cap seal comprising a base (38) with a continuous wall (40) upstanding from the periphery thereof which is of substantially rigid material and which is securable to the said other of the stationary support or the caliper, and an elastomeric seal (42) secured to the continuous wall for making a seal with the said other of the stationary support or the caliper around the said one end of the axial bore. Provides an improved cap seal.
Patent DE-69003496-T2 (DE)
Inventor: VAYSSIE CHARLES
IPC: A61Q5/10
Filed: 1990-07-18
Granted: 1994-01-20
Abstract: Process for dyeing keratinous fibres, especially human keratinous fibres, wherein
 - in a first step, a composition (A) is applied, containing, in a medium suitable for dyeing and free from any oxidising agent, at least one indole dye corresponding to the formula: 
<IMAGE>
 in which: 
 
  R1 represents a hydrogen atom, a lower alkyl group or a group -SiR6R7R8; 
  R2 and R3, which may be identical or different, represent a hydrogen atom or alternatively a lower alkyl group, a carboxyl group, a (lower alkoxy)carbonyl group or a group -COOSiR6R7R8; 
  R4 and R5, which may be identical or different, represent a hydrogen atom, a linear or branched C1-C20 alkyl group, a formyl group, a linear or branched C2-C20 acyl group, a linear or branched C3-C20 alkenoyl group, a group -SiR6R7R8, a group -P(O)(OR9)2, or a group -SO2OR9, or alternatively R4, R5, together with the oxygen atoms to which they are attached, form a ring optionally containing a carbonyl group, a methylene group, a thiocarbonyl group or a group: 
<IMAGE>
 or alternatively 
<IMAGE>
 
  R9 and R10 represent a hydrogen atom or a lower alkyl group, 
  R11 representing a lower alkoxy group or a lower mono- or dialkylamino group, 
  R6, R7 and R8, which may be identical or different, representing linear or branched lower alkyl groups; 
 and the addition salts with inorganic or organic acids, as well as the corresponding salts of alkali metals, alkaline earth metals or amines;
 - in a second step, there is applied on these fibres a composition (B) containing, in a medium suitable for dyeing, at least one para oxidation dye precursor chosen from para-phenylenediamines, para-aminophenols and heterocyclic para bases chosen from pyridine derivatives or pyrimidine derivatives and/or at least one so-called ''rapid'' oxidation dye chosen from trihydroxy derivatives of benzene, diaminohydroxybenzenes, aminodihydroxybenzenes, substituted aminohydroxybenzenes, triaminobenzenes, substituted 1,2-dihydroxybenzenes, brazilin, haematoxylin and alkanet extract, the composition (B) optionally being mixed at the time of use with a solution of hydrogen peroxide.
Patent DE-69009224-T2 (DE)
Inventor: GAZERRO LAURA
IPC: C07C235/34
Filed: 1990-02-16
Granted: 1994-09-22
Abstract: This invention relates to new gem-diamino derivatives of general formula (I)  X-NH- @H-NH2      (I)    where R is the side chain of an amino acid, of which any functional groups are suitably protected, and X is an acyl group chosen from the group consisting of 2-nitro-benzoyl, 4-chloro-butyryl, acetoacetyl, 4-bromo-butyryl, (2-nitro-phenoxy)-acetyl and 2-methyl-2-(2 min -nitro-phenoxy)propionyl, of use in introducing gem-diamino residues into retro-inverso peptides. The invention further relates to a method for the synthesis of retro-inverso peptides in which the gem-diamino residue or residues are introduced using the new compound (I).
Patent DE-69009864-T2 (DE)
Inventor: BEAUFILS JEAN-MARIE
IPC: H04L12/40
Filed: 1990-06-22
Granted: 1994-09-22
Abstract: This protection device for a digital signal transmission system comprises, in at least one of the items of terminal equipment of this system, a logic circuit ensuring a placing of the output of this item of equipment in the high-impedance state or at a specified potential in the event of a break in the supply to the logic circuits forming this item of equipment. 
<IMAGE>
Patent DE-69010105-T2 (DE)
Inventor: SCHOUBYE PETER
IPC: B01D53/56
Filed: 1990-02-05
Granted: 1994-12-01
Abstract: PCT No. PCT/DK90/00030 Sec. 371 Date Oct. 10, 1990 Sec. 102(e) Date Oct. 10, 1990 PCT Filed Feb. 5, 1990 PCT Pub. No. WO90/09228 PCT Pub. Date Aug. 23, 1990.Nitrogen oxides can be removed from turbines by a selective catalytic reduction (SCR) with ammonia with greater efficiency than by prior art technique if the ammonia needed for the reduction of the nitrogen oxides is added before the turbine, preferably in a stoichiometric excess compared to the contents of nitrogen oxides in the exhaust gas. One can employ well-known SCR catalysts and advantageously the exhaust gas after the turbine is passed through a layer of SCR catalyst followed by a layer of a combustion catalyst. The latter expediently consists of metal oxides, preferably selected from copper oxide, manganese oxide and chromium oxide, deposited on aluminum oxide, magnesium oxide, silicon oxide or mixtures thereof.
Patent DE-69019392-T2 (DE)
Inventor: JARVIS CHARLES RICHARD
IPC: B42D15/10
Filed: 1990-01-18
Granted: 1995-10-05
Abstract: In order to allow a thin portable token of the Smart Card type to be flexible, yet protect the electronic components (2) within it, the token is manufactured from a resin material and includes high tensile foil inserts (7a, 7b) above and below the component - producing a double skinned effect to stiffen and strengthen the token in the region of the component. The components are mounted on a substrate (3), which also acts as a hinge between components to enable flexing of the token as a whole. Alternative comprise frames (15) encircling each component (2) or moulded resin members (11) encapsulating the components (2).
Patent DE-69024061-T2 (DE)
Inventor: BERGOT JOHN
IPC: C07H19/20
Filed: 1990-09-27
Granted: 1996-08-08
Abstract: A spectrally resolvable set of rhodamine dyes are provided for use in the chain termination method of nucleic acid sequencing. A different rhodamine dye from the group consisting of tetramethylrhodamine, rhodamine X, rhodamine 6G, and rhodamine 110 is attached to the base of each of the dideoxynucleotides used in the sequencing method by way of an alkynylamino linker. Preferably, the labeled dideoxynucleotides are incorporated into the growing DNA chains by Taq DNA polymerase.
Patent DE-69029579-T2 (DE)
Inventor: SCARBOROUGH ROBERT
IPC: C07K14/435
Filed: 1990-06-15
Granted: 1997-07-24
Abstract: An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K*-(G/Sar)-D wherein K* is a modified lysyl residue of the formula R<1>2 N(CH2)4CHNHCO- wherein each R<1> is independently H, alkyl(1-6C) or at most one R<1> is R<2>-C=NR<3> wherein R<2> is H, alkyl(1-6C), phenyl or benzyl, or is NR<4>2 in which each R<4> is independently H or alkyl(1-6C) and R<3> is H, alkyl(1-6C), phenyl or benzyl, or R<2>-C=NR<3> is a radical selected from the group consisting of: <CHEM> where m is an integer of 2-3, and each R<5> is independently H or alkyl(1-6C); and wherein one or two (CH2) may be replaced by O or S provided said O or S is not adjacent to another heteroatom are prepared and shown to specifically inhibit the binding of fibrinogen or von Willebrand Factor to GP IIb-IIIa.
Patent DE-69115702-T2 (DE)
Inventor: WEIS ALEXANDER
IPC: C07H21/00
Filed: 1991-08-02
Granted: 1996-06-13
Abstract: The present invention relates to compounds, compositions and methods for inhibiting gene expression. The compounds of this invention comprise 1) oligonucleoside sequences of from about 6 to about 200 bases having a three atom internucleoside linkage or 2) oligonucleotide sequences of from about 9 to about 200 bases having a diol at either or both termini.
Patent DE-69117214-T2 (DE)
Inventor: GARCIA BALLESTEROS ANGEL
IPC: E01F9/685
Filed: 1991-05-29
Granted: 1996-10-02
Abstract: The barrier consists of a series of light weight modules, filled of a conventional material as ballast to give them stability and resistance. The modules are noticeably rectangular prismatic bodies with top apertures (4) which act as loading nozzles for the filling material, and with lower transversal canals for the circulation of water. One type of module is male and the other female, and to form the barrier they are placed alternatively the ones on the others on the wearing course of the road. The modules can be dismantled to leave an open way in the barrier; they can be articulated or even rigid between themselves and anchored to the ground. <IMAGE>
Patent DE-69126215-T2 (DE)
Inventor: SKINNER PAUL R J
IPC: B23P15/42
Filed: 1991-11-25
Granted: 1997-10-02
Abstract: A rotary disc cutter for cutting workpieces, especially gears and the like. The rotary cutter comprises a plurality of cutting blades arranged about the periphery of a rotary disc cutting body with at least a portion of the blades being roughing blades comprising a tip and two sides with each side having first and second side portions. The first side portion along with the tip defining a cutting surface of the blades while the second side portion is relieved such that a clearance is formed between the second side portion and the surface of the workpiece. The clearance being of a dimension to allow the flow of coolant therethrough thereby improving the cooling of the cutting surface and enhancing the flow of chips away form the vicinity of the blades. The invention further includes a substantially reduced number of blade segments. Alternative blade tip configurations are also disclosed.
Patent DE-69127094-T2 (DE)
Inventor: VIZER DAVID
IPC: H04N5/45
Filed: 1991-11-05
Granted: 1997-11-20
Abstract: Within a television receiver adapted for MAC reception and including a PIP processor in case the MAC signal is fed to the PIP processor a MAC decoder is needed as the PIP processor can handle only the composite PAL video signal. It is an object to simplify the circuit means in case of PIP display of a MAC signal. According to the invention switching means S3 are provided for connecting the input of the PIP processor to the output of a PAL encoder which is provided for furnishing output signals for a video tape recorder. Especially for a colour television receiver designed for MAC reception and PIP display.