baber/WOPTO huggingface dataset:
Patent CO-6220951-A2 (CO)
Title: 4-aril-1,4-dihidro-1,6-naftiridinamidas sustituidas y su uso
Inventor: BAERFACKER LARS
IPC: A61K31/437
Filed: 2009-08-18
Abstract: 1.- Compuesto de fórmula (I)en la que D representa N o C-R4 en la que R4 significa hidrógeno, flúor, trifluorometilo o alquilo (C1-C4), Ar representa un grupo de fórmulaen las que * significa el punto de unión, R5 significa hidrógeno, flúor, cloro, ciano, nitro, trifluorometilo o alquilo (C1-C4), R6 significa hidrógeno o flúor, R7 significa halógeno, alquilo (C1-C4), trifluorometilo, alcoxi (C1-C4) o trifluorometoxi, R8 significa ciano o nitro, R9 significa hidrógeno halógeno, alquilo (C1-C4), alcoxi (C1-C4), alquiltio (C1-C4) o dialquil (C1-C4)-amino, pudiendo estar el grupo alquilo en los restos alquilo (C1-C4), alcoxi (C1-C4) y alquiltio (C1-C4) mencionados respectivamente sustituido hasta tres veces con flúor,o fenilo que puede estar sustituido con halógeno, alquilo (C1-C4) o trifluorometilo, R10 significa hidrógeno, halógeno o alquilo (C1-C4), E significa CH, C-R7 o N y n significa el número 0, 1 ó 2, pudiendo ser sus significados iguales o distintos para el caso en que el sustituyente R7 aparezca varias veces, R1 representa alquilo (C1-C4) que puede estar sustituido hasta tres veces con flúor, R2 representa alquilo (C1-C6) que puede estar sustituido con cicloalquilo (C3-C7) o hasta tres veces con flúor, o representa un grupo de fórmula SO2-R11 en la que R11 significa alquilo (C1-C6), trifluorometilo, cicloalquilo (C3-C7), ...
Patent CO-6251287-A2 (CO)
Title: Derivados de oxadiazol y su uso como potenciadores de los receptores metabotropicos de glutamato -842
Inventor: CLAYTON JOSHUA
IPC: A61K31/496
Filed: 2009-12-04
Abstract: 1.- Un compuesto de acuerdo con la Fórmula I:donde R1 es halo o C1-3 haloalcoxilo; Q es y R2 es hidrógeno o C1-3 alquilo, o una sal, un hidrato, un solvato, un isómero óptico o una combinación farmacéuticamente aceptable de este. 2.- Un compuesto de acuerdo con la Reivindicación 1, donde R1 es cloro o trifluorometoxilo o una sal, un hidrato, un solvato, un isómero óptico farmacéuticamente aceptable de este. 3.- Un compuesto de acuerdo con la Reivindicación 2, donde R1 es trifluorometoxilo o una sal, un hidrato, un solvato, un isómero óptico farmacéuticamente aceptable de este. 4.- Un compuesto de acuerdo con la Reivindicación 1, donde Q es o una sal, un hidrato, un solvato, un isómero óptico farmacéuticamente aceptable de este. 5.- Un compuesto de acuerdo con la Reivindicación 4, donde Q es y R2 es H o una sal, un hidrato, un solvato, un isómero óptico farmacéuticamente aceptable de este. 6.- Un compuesto de acuerdo con l Reivindicación 1, donde R1 es cloro o trifluorometoxilo y Q eso una sal, un hidrato, un solvato, un isómero óptico farmacéuticamente aceptable de este. 7.- Un compuesto de acuerdo con la Reivindicación 6, donde R1 es trifluorometoxilo y Q eso una sal, un hidrato, un solvato, un isómero óptico farmacéuticamente aceptable de este.
Patent CO-6300861-A2 (CO)
Title: Compuestos inhibidores de dipeptidil peptidasa iv metodos de preparacion de los mismos y composiciones farmaceuticas que los contienen como agentes activos
Inventor: LEE CHANG-SEOK
Filed: 2010-06-21
Abstract: 1.- Un compuesto representado por la fórmula 1: en donde A se selecciona de un sustituyente de fórmula 2: en donde R1 es hidrógeno o CF3, y R2 se selecciona del grupo que consiste en hidrógeno, alquilo de C1-C10 sustituido o no sustituido, cicloalquilo de C3-C10 sustituido o no sustituido, heterocicloalquilo de C3-C10 sustituido o no sustituido, arilo de C4-C8 sustituido o no sustituido y heteroarilo de C3-C7 sustituido o no sustituido; y un sustituyente de fórmula 3: en donde R3 se selecciona del grupo que consiste en hidrógeno, halógeno y alquilo de C1-C4 sustituido o no sustituido; y B se selecciona del grupo que consiste en un sustituyente de fórmula 4: en donde X es -CR4R5- o -CO-, en donde R4 y R5 son, cada uno independientemente, hidrógeno o hidroxi, siempre que por lo menos uno de R4 y R5 sea hidroxi; cada uno de R6, R7, R8 y R9 se selecciona independientemente del grupo que consiste en hidrógeno, halógeno y alquilo de C1-C4 sustituido o no sustituido, y n es 0 o 1;
Patent CO-6311058-A2 (CO)
Title: Un implemento para almacenamiento y entrega de múltiples agentes que pueden reaccionar entre si
Inventor: KEMP JAMES H
IPC: A46B11/00
Filed: 2010-12-02
Abstract: Se describe un implemento de reacción y entrega que incluye un mango configurada para su manipulación por el usuario, un cabezal que tiene una pluralidad de regiones de alojamiento del agente, reteniendo la primera región de alojamiento de agente a un primer agente y reteniendo la segunda región de alojamiento de agente a un segundo agente, siendo distintos el primer y el segundo agentes. Se configura al cabezal para que facilite tanto la prevención del entremezclado de los agentes primero y segundo en una posición de almacenaje, así como la reacción de los agentes primero y segundo por medio del entremezclado en una posición de entrega para producir y aplicar un tercer agente cuando está en la posición de entrega. El implemento de reacción y entrega podría ser un implemento de cuidado oral tal como un cepillo de dientes. También se puede motorizar el implemento y se podría usar con un amplio arreglo de reacciones.
Patent CO-6741224-A2 (CO)
Title: Formas cristalinas de un ácido alcoxiimidazol-1-ilmetil bifenil carboxílico
Inventor: FATHEREE PAUL
IPC: C07D233/70
Filed: 2013-05-03
Abstract: Formas de sal cristalina de ácido 4-{2-etoxi-4-etil-5-[((S)-2-mercapto-4-metilpentanoilamino)metil]imidazol-1-ilmetil}-3-fluoro bifenil-2-carboxílico. La presente invención también proporciona composiciones farmacéuticas que comprenden los compuestos cristalinos, procesos e intermediarios para preparar los compuestos cristalinos, y métodos para usar los compuestos cristalinos para tratar enfermedades tales como la hipertensión.
Patent CO-6771414-A2 (CO)
Title: Métodos de tratamiento usando compuestos lípidos
Inventor: HOVLAND RAGNAR
IPC: A61K31/19
Filed: 2013-06-05
Abstract: La presente invención se relaciona con métodos para tratar o prevenir por lo menos una enfermedad o afección en un paciente en necesidad del mismo, que comprende administrar un compuesto de la Fórmula I o una sal farmacéuticamente aceptable o éster del mismo, en donde en donde Ry Rse eligen independientemente de un átomo de hidrógeno o grupos alquilo C-Clineales, ramificados y/o cíclicos, con la condición de que Ry Rno sean ambos hidrógeno o una sal o éster farmacéuticamente aceptables del mismo. Estas enfermedades o afecciones se pueden relacionar con enfermedad cardiaca coronaria (CHD), por ejemplo, aterosclerosis, síndrome metabólico/resistencia a la insulina; y/o una afección dislipidémica, tales como hipertrigliceridemia (HTG), colesterol LDL elevado, colesterol total elevado, colesterol Apa B elevado y HDL bajo. La presente descripción además proporciona un método para reducir el desarrollo de aterosclerosis. También se describen composiciones farmacéuticas que comprenden un compuesto de la Fórmula (I).
Patent CO-7240404-A2 (CO)
Title: Tapón para envases, por ejemplo para botellas o bolsas flexibles, por ejemplo para bebidas infantiles
Inventor: TAMARINDO STEFANO
IPC: B65D75/58
Filed: 2014-12-12
Abstract: Un tapón (1) para un envase o para una pajita para una bolsa flexible, enparticular para contener alimentos líquidos, tales como zumo de frutas u otras bebidassimilares, que está provisto de un precinto de garantía (8) y una pared anular (10) quetiene un reborde (10a) libre inferior que tiene un diseño ondeado para observar mejor elprecinto de garantía.
Patent EP-1022330-A2 (EP)
Inventor: LEVESQUE MICHEL F
IPC: A61K35/12
Filed: 2000-01-20
Abstract: Disclosed is a method of transdifferentiating an epidermal basal cell into a cell having
one or more morphological, physiological and/or immunological features of a neural
progenitor, neuronal, or glial cell by culturing a proliferating epidermal basal cell population
derived from the skin of a mammalian subject; exposing the epidermal basal cell(s) to an
antagonist of bone morphogenetic protein (BMP), such as fetuin, noggin, chordin, gremlin,
or follistatin; and growing the cell(s) in the presence of at least one antisense oligonucleotide
comprising a segment of a human MSX1 gene and/or a segment of a human HES1 gene, or
homologous non-human counterpart of either of these. Also disclosed is a transdifferentiated
cell of epidermal origin and cell cultures derived therefrom. In addition, methods of using
the inventive transdifferentiated cell(s) and cell cultures to identify a novel nerve growth
factor or to screen a potential chemotherapeutic agent by detecting the presence or absence
of an effect, in vitro, on a morphological, physiological and/or molecular biological property
of the transdifferentiated cell(s) are described, as is a method of using the transdifferentiated
cell(s) and cell cultures to screen a potential chemotherapeutic agent to treat a nervous system
disorder of genetic origin. A kit useful for practicing the methods is disclosed
Patent EP-1025958-A2 (EP)
Inventor: JESPERSEN POUL ERIK
IPC: B24D13/10
Filed: 2000-01-28
Abstract: The invention concerns a rotatable grinding/polishing tool, an apparatus with such a
tool and a method for using such a tool. The tool has grinding elements in the shape of
grinding/polishing flaps extending radially outward from a roller. Reinforcing support
brushes also extend radially outward and adjacent to the flaps. Furthermore, the tool
has holding elements, preferably in the shape of brushes, likewise extending radially
outwards from the roller. The holding brushes have substantially lesser length than the
flaps and the reinforcing support brushes. At the same time, the tangential stiffness of
the holding brushes is considerably greater than the tangential stiffness of the flaps
and the support brushes. The length of the grinding flaps is preferably so that by
grinding or polishing, the flaps are capable of extending beyond an adjacent holding
element.
Patent EP-1037486-A2 (EP)
Inventor: BAUMGARTEN HANS-GEORG
IPC: H04W72/06
Filed: 2000-03-15
Abstract: The transmission channel selection method uses initial identification of all available transmission channels and subsequent evaluation of the available transmission channels, for selection of the transmission channel with the optimum channel characteristics for the required service.  The channel evaluation may be effected by comparing stored values corresponding to the required service with actual measured characteristic values for the transmission channel using an evaluation function.
Patent EP-1054385-A2 (EP)
Inventor: CORRELL KENNETH W
IPC: G06T15/00
Filed: 2000-05-18
Abstract: A state machine controls a voxel memory storing a volume data set to be processed
by rendering pipelines. The state machine includes a precharge state to periodically
maintain data in the memory, a state for synchronously transferring data from the
memory to a plurality of rendering pipelines, a read state for asynchronously
transferring data from the memory to a host computer; and a write state for
asynchronously transferring data from the host computer to the memory. The state
machine decodes memory access requests, the requests including render, read,
write, and maintenance requests. The render requests have priority over the
maintenance requests, which have priority over the read and write requests.
Patent EP-1057693-A2 (EP)
Inventor: MIZUTANI KENICHI
IPC: B60R1/08
Filed: 2000-05-26
Abstract: The electrochromic anti-glare mirror (10) includes an electrochromic layer
which is provided at a rear surface side of a substrate glass (14), and in
which an electrochromic film (18) is nipped between a transparent
conductive film (16) and a reflective conductive film (20). By energizing the
electrochromic film (18) between the transparent conductive film (16) and
reflective conductive film (20), the electrochromic film (18) is electrically made to
color. Wires for electrochromic anti-glare (10) for energizing the
electrochromic film between the transparent conductive film and the
reflective conductive film are printed on the printed circuit board.
Patent EP-1065575-A2 (EP)
Inventor: KATANABE NOBORU
IPC: G03G15/08
Filed: 2000-06-27
Abstract: An image forming unit equipped with a handle and having a compact
size with a smaller containing space required. The image forming unit is
produced by forming the rectangular concave portion 201 along the
longitudinal direction; which contains a handle 200 made of an elastic
rectangular-shaped plate; providing elongated holes extending in the
longitudinal direction at both ends of the handle 200; and engaging the
elongated holes 202 with anchoring member 203 provided at the concave
portion 201. The handle 200 is allowed to have a state in which it is
contained in the concave portion 201 by its elastic force (non-holdable
posture).
Patent EP-1072932-A2 (EP)
Title: Liquid crystal elemental device, production process thereof and spacer-bearing substrate
Inventor: HIROSE MASASHI
IPC: G02F1/1335
Filed: 2000-07-27
Abstract: Disclosed herein is a process for producing a
liquid crystal elemental device comprising a pair of
substrates arranged in opposed relation to each other
through a spacer and a liquid crystal held in a space
between the substrates, which comprises the steps of
applying a spacer-forming material onto one of the pair
of substrates by an ink-jet system to form the spacer,
arranging the pair of substrates in opposed relation to
each other with the spacer held therebetween, and
enclosing a liquid crystal compound in the space
between the pair of substrates.
Patent EP-1090753-A2 (EP)
Inventor: SCHWEIGERT FRANZ
IPC: B41F27/00
Filed: 2000-08-18
Abstract: Printing blocks are applied precisely to the surface of the printing cylinder and aligned using stop pieces on the blocks and on the cylinder in the region of an axial surface line. The stop pieces include two axially spaced stops (4,5) on the cylinder, at least one of which (4) comprises an adjusting device (12) which is effective in the circumference direction. The stops may consist of matching pins which stand above the surface of the printing cylinder, and which match holes in the blocks.
Patent EP-1033543-A2 (EP)
Inventor: DAVIS JOHN E
IPC: B64G1/40
Filed: 2000-03-03
Abstract: Slush (12) is made from a liquid (14) using slush making systems (10) or according to
slush making processes. A jacketed vessel (20) of the processes and the systems has
an interior wall (26) that defines an interior space (28). The interior space (28) comprises a top (32)
and a bottom (30). The interior space (28) has an average overall cross-sectional area taken
through a vertical axis extending generally between the top (32) and the bottom (30). The
interior space (28) also has a collection portion having an average collection portion
cross-sectional area taken through the vertical axis that is less than the average
overall cross-sectional area. The liquid is placed into the interior space and the
interior walls (26) are cooled. Slush (12) forms on the interior walls (26) and migrates to the
collection portion. The collection portion (36) is located at the interior space bottom (30)
when the slush density is higher than the liquid density and the collection portion (36)
is located at the interior space top (32) when slush density is less than the liquid
density. To facilitate the migration of the slush to the collection portion, at least a
conical portion of the interior space (28) has the general shape of a cone and the
collection portion (36) is located in the proximity of an apex (30) of the conical portion,
thereby helping to funnel the slush (12) to the collection portion (36). The cryogenic liquid
to be made into slush may be oxygen, nitrogen, hydrogen, helium, or water. The
slush (12) may be used to densify cryogenic liquids, such as cryogenic liquid
propellants.
Patent EP-1057496-A2 (EP)
Inventor: FLAMMANG DANIEL DR
IPC: A61N1/39
Filed: 2000-06-02
Abstract: An electrode arrangement, in particular for the intracardial discharge of defibrillation
pulses in the atrium of a heart, comprising an electrode line which in the
region of its distal end has a plurality of electrically conductive surface portions as
electrodes which can be electrically connected by way of the electrode line to an
electrical pulsedischarging device such as defibrillator, wherein the electrode line
is adapted to be split in the electrode-bearing region of its distal end into at least
two respectively electrode-bearing branches.
Patent EP-1085394-A2 (EP)
Inventor: KAMADA JUN
IPC: G10L25/51
Filed: 2000-08-08
Abstract: The apparatus controls access to content such as
software, music or movies stored in digital form on a
storage medium such as a magneto-optical [MO] disc.
The apparatus comprises an MO disk drive (120), MPEG2
decoder (130), and MO disk (140) as physical elements.
Information for identifying these physical elements
(identifying information) is allocated to each of these
physical elements. License information, indicating
whether access to the content is to be allowed or not,
is recorded on the disk. Access to the content
recorded on the disk is controlled based on the license
information and the identifying information.
Patent EP-1129626-A2 (EP)
Inventor: ALTEMUELLER ANDREAS G
IPC: A23L13/60
Filed: 2000-08-17
Abstract: A soy functional food ingredient is provided comprising a flaked, comminuted,
or particulate soy material containing less than 65% soy protein by weight on a
moisture-free basis, wherein at least a portion of the soy protein is irreversibly partially
denatured. In one embodiment, the soy material of the functional food ingredient also
has a nitrogen solubility index of from about 30% to about 80% and at least one of the
following properties: a water activity of 0.3 or less; a salt tolerance index of from about
30% to about 80%; a water hydration capacity of at least 3 times the weight of the soy
material; a viscosity of at least 500 mPa.s (centipoise) at a temperature of 18°C to 25°C;
and a trypsin inhibitor activity of at most 10 trypsin inhibitor units per milligram of the
soy material. In another embodiment, the soy material of the functional food ingredient
also has at least one of the following properties: a gel weight of at least 30 grams at a
temperature of from about 15°C to about 25°C in a 150 ml (5 ounce) aqueous slurry
containing 5 parts water per part of soy material, by weight; and a refrigerated gel
strength of at least 50 grams when combined with 5 parts of water per part of soy
material, by weight.
Patent EP-1107067-A2 (EP)
Inventor: KWAN YIMBUN PATRICK
IPC: G03F7/20
Filed: 2000-11-22
Abstract: An H-drive arrangement for the substrate or mask stages of a lithographic apparatus has
an X-beam 11 rigidly mounted to Y-sliders 121a, 121b against X and Y translation and rotation
about a Z axis (yaw) so as to form a rigid body in the XY plane. Rotation about X and Y axes is
permitted in the joint between at least one Y-slider 121a, 121b and X-beam 11. Crash protection
may be provided by a yaw rate sensor and/or resilient buffers which contact Y-beams 12a, 12b in
the event of out-of-range yaw motions.
Patent EP-1113469-A2 (EP)
Inventor: KIMURA KOUJI
IPC: D04H1/435
Filed: 2000-12-20
Abstract: A separator for an electric double-layer capacitor
with an excellent property of preventing a short circuit
between the electrodes, a good ionic permeability and a high
strength is provided which comprises a fiber sheet comprising
a fibril-containing fiber and a fine polyester fiber having a
fineness of not more than 0.45 dtex (decitex).
Patent EP-1094602-A2 (EP)
Inventor: MUKAI TAKAO
IPC: H03H9/02
Filed: 2000-10-17
Abstract: A surface acoustic wave device includes a piezoelectric substrate (2)
having a pair of substrate edges (21,22) and an upper surface therebetween. The
piezoelectric substrate has at least one inner edge (23a) which is in contact with a
main region and extends from the upper surface toward a bottom surface of the
piezoelectric substrate inside one of the substrate edges. An interdigital
transducer (3/4) is provided on the main region of the piezoelectric substrate such
that a SH type surface acoustic wave excited by the interdigital transducer and
having a wavelength of λ is reflected by the at least one inner edge (23a). A
distance L between the at least one inner edge (23a) and the corresponding one of
the substrate edges (21) is substantially equal to about 8λ or less.
Patent EP-1144988-A2 (EP)
Title: Device for the precision rotation of samples
Inventor: CIPRIANI FLORENT
IPC: G01N23/20
Filed: 2000-01-07
Abstract: A centering element (26) with single-unit sample holder (30) is used for concentric mounting of a sample (32) to a rotational axis. At least a micrometer finger (36) is arranged in a region of the centering element (26), which may be positioned through a micrometer finger drive orthogonal to the rotational axis of the rotary shaft (22).
Patent EP-1202629-A2 (EP)
Inventor: CRAIG ROGER
IPC: A01N63/50
Filed: 2000-08-07
Abstract: A method for controlling a population of target insects comprising providing a gene comprising a coding sequence encoding one constituent of an enzyme/pro-pesticide system and a regulatory region operatively linked to said coding sequence. The regulatory region of the present invention regulates expression of said coding sequence in a target insect of said population of target insects in a sex specific manner. The method of the present invention further comprises transforming a plurality of said target insects with said gene, and allowing said gene to spread within the target insect population. The method further comprises administering to said population of target insects the remaining constituent(s) of said enzyme/pro-pesticide system wherein said enzyme catalyzes the conversion of the pro-pesticide to a pesticide.
Patent EP-1268935-A2 (EP)
Inventor: SCHWENK GERHARD
IPC: D21H21/48
Filed: 2000-12-20
Abstract: The invention relates to a security paper with at least two types of mottled fibers, which differ in terms of their luminescent characteristics and form a code. In each case one type of mottled fibers is present in a defined subarea of the security paper, and the code is represented by the defined geometric arrangement of the subareas on the security paper and/or by the presence or absence of mottled fibers of a specific type.
Patent EP-1111930-A2 (EP)
Inventor: KADONO SHINYA
IPC: H04N19/20
Filed: 1998-01-23
Abstract: An object of this invention is to provide a coding method and a coding apparatus for efficiently coding both a pixel value signal and a shape signal which are included in an image signal to be coded, wherein a prediction changing unit outputs a reference pixel value changing signal and a reference shape signal to a switching circuit which selects a reference pixel value signal and to a switching circuit which selects a reference shape signal, respectively, so as to control the switching circuit in a way that appropriate reference signals are to be selected.
Patent EP-1135004-A2 (EP)
Inventor: NISHII HIROYUKI
IPC: B01D53/26
Filed: 2001-03-16
Abstract: A member for an electroluminescent device is described,
comprising a container a part of which is made of a porous
material and a removing agent capable of removing a prescribed
gaseous component, the removing agent being contained in said
container. An electroluminescent device having the member is
also described.