baber/WOPTO huggingface dataset:
Patent ES-557559-A0 (ES)
IPC: C07H19/02
Filed: 1987-05-21
Abstract: New griseolic acid derivatives have various groups attached to the sugar part in place of the adenine group of griseolic acid itself. These groups are all purine derivatives or ring-opened purine analogs. The compounds are useful as inhibitors of phosphodiesterases. They may be prepared by replacing the adenine moiety of griseolic acid and/or dihydrodesoxygriseolic acid and/or by replacing other substituent groups.
Patent FI-833729-A0 (FI)
Inventor: HADLER MALCOLM RONALD
IPC: A01N43/90
Filed: 1983-10-13
Abstract: A rodent bait comprising food and a poison, said poison being wholly in the form of, or contained in, one or more discrete poison-providing particles of such activity with respect to the rodent specie for which the bait is intended that each poison-providing particle provides a lethal dose with respect to an adult rodent of that specie, each poison-providing particle being substantially homogeneous and being of a particle size which is such that a rodent of the specie for which the bait is intended will take the particle into its mouth without prior nibbling.
Patent FI-840684-A0 (FI)
Inventor: GOUGH PETER ROBERT
IPC: B21C43/04
Filed: 1984-02-20
Abstract: The invention provides for surface cleaning of wire rod and the like by holding the wire (10) under tension while passed through a die system (16) and vibrating the wire (10) transversely so that it is abraded by the surface. Cleaning liquid flushes the die bore.
Patent FI-844748-A0 (FI)
Inventor: OAKES JOHN
IPC: C11D3/08
Filed: 1984-12-03
Abstract: Detergent bleach compositions comprising a peroxide compound bleach, a manganese bleach catalyst and sodium sesquisilicate and/or sodium metasilicate, having a solution pH of from 9.5 to 13. The compositions show enhanced bleaching effect and are suitable for the laundering of fabrics at lower temperatures of between 20 and 60°C.
Patent FI-850282-A0 (FI)
Inventor: SMITS PETER CAROLUS CORNELIS
IPC: C07H7/027
Filed: 1985-01-22
Abstract: Preparation of 2-keto-aldonic acids, e.g., 2-keto-gluconic acid, by oxidizing an aldose, e.g. glucose, or aldonic acid in aqueous solution with molecular oxygen. Use is made of a pletinum catalyst together with a catalytic amount of lead and/or bismuth and/or a compound thereof. The pH of the solution is in the range of from 4 to 12 and preferably in the range of from 7 to 9. The reaction may be carried out at a temperature in the range of 0 to 200°C and preferably in the range of from 25° to 80°C.
Patent FI-861683-A0 (FI)
Inventor: BOESHAGEN HORST
IPC: C07D209/16
Filed: 1986-04-22
Abstract: The invention relates to N-indolylethyl-sulphonic acid amides of the formula   <IMAGE>   wherein R1, R2, R3, R4 and R5 are defined in the specification and X is carboxyl, alkoxycarbonyl, cyano or carboxamido. These active compounds are useful in medicaments in combating thromboses, thromboembolisms, allergies or asthmatic disorders.
Patent FI-872231-A0 (FI)
Inventor: BENJAMIN ERIC JOEL
IPC: A61K31/57
Filed: 1987-05-21
Abstract: A non-stinging aqueous anti-inflammatory steroid formulation suitable for intranasal administration comprises: an anti-inflammatory steroid in an amount between about 0.01% and about 0.05% (w/v); propylene glycol in an amount between about 2% and about 10% (w/v); PEG 400 in an amount between about 10% and about 25% (w/v); polysorbate 20 in an amount between about 1% and about 4% (w/v); an effective amount of a preservative; an effective amount of a stabilizer; an effective amount of an antioxidant; water; and pH buffering agent sufficient to adjust the pH of the resulting solution to between about 3.5 and about 7.
Patent FI-882517-A0 (FI)
Inventor: ZOECKLER MARY THERESE
IPC: C08F10/00
Filed: 1988-05-27
Abstract: An ethylene polymerization catalyst comprising: (i) a complex having at least one cation and at least one anion wherein the cation is V2X3(ED)m and the anion is MaClbRc wherein X = Cl, Br, or I, or mixtures thereof, ED = an electron donor selected from the group consisting of ethers, phosphines, ketones, isocyanides, and esters, each electron donor having 2 to 20 carbon atoms, M = Al or Mg, R = an alkyl radical having 1 to 14 carbon atoms, m = an integer from 3 to 6, a = 1 or 2, b = 2 when M = Al and 3 when M = Mg, c = 2 when M = Al and 0 when M = Mg, said complex impregnated on an inorganic oxide support; (ii) a halocarbon promoter; and (iii) a hydrocarbyl aluminum cocatalyst.
Patent FI-885821-A0 (FI)
Inventor: LISIECKI ROBERT E
IPC: B65D5/06
Filed: 1988-12-16
Abstract: A flat top, thermoplastic coated, paperboard container having weakened lines (48a,b,c) formed thereon such that the top (44) may be opened by breaking through a weakened line at the front (22) and progressively breaking the weakened lines along the sides upon peeling back the cover panel, to provide access to the contents. Provisions (76) are included for covering the weakened lines on the inside of the container to prevent leakage.
Patent FI-894159-A0 (FI)
Inventor: GARTH PETER
IPC: G03F7/20
Filed: 1989-09-04
Abstract: The invention relates to an automatic machine for the reversal processing of lithographic printing plates which are required to be exposed overall after heating. The method and apparatus of the invention provide that the exposure be effected while the plates are being conveyed through water in a shallow bath.
Patent FI-895122-A0 (FI)
Inventor: VIEGENER WALTER
IPC: E03C1/29
Filed: 1989-10-27
Abstract: The discharger armature, which is used especially for shower bottoms, consists of a housing (7) provided with an inflow opening, a discharge socket (22) and a fastening flange (6) and of an immersion pipe (15) inserted into the housing and delimiting the inflow opening. The housing (7) contains an outer annular channel (19) and an upper discharge channel (21). The fastening flange (6) of the housing, which is fixed to the edge of a base opening (2) in the shower bottom, is arranged offset downwards with respect to the upper housing wall (13), which delimits the upper discharge channel (21). The bottom (20) of the outer annular channel (19) is inclined towards the discharge socket (22). As a result of this inclination of the bottom of the outer annular channel, in the case of a large flow cross-section of the annular channel, on the one hand, the discharging capacity is improved and, on the other hand, self-cleaning of the discharger armature is achieved. The discharger armature has a low overall height and a high throughput capacity. <IMAGE>
Patent FI-900536-A0 (FI)
Inventor: JACKSON WILLIAM PAUL
IPC: A61P11/00
Filed: 1990-02-02
Abstract: The present inventions concerned with compounds of formula (I) <CHEM>  wherein  Ar is 4-halophenyl;  Ar min  is 1,3- or 1,4-phenylene;  Y is (E)-CH=CH-; and R<1> and R<2> are independently selected from hydrogen and C1-4 alkyl; and base salts and physiologically functional derivatives thereof, processes for their preparation, pharmaceutical formulations containing them and, optionally, one or more other pharmacologically active ingredients and the use of these compounds in medicine.
Patent FI-911751-A0 (FI)
Inventor: FARR ROBERT A
IPC: C07C215/44
Filed: 1991-04-11
Abstract: Substituted (1 alpha , 2 beta , 3 alpha  or  beta , 4 alpha  5 alpha or  beta )-2,3,4-trihydroxy-5-(hydroxymethyl)cyclopentylamines are inhibitors of alpha-mannosidase and alpha-fucosidase and are useful immunostimulants, antiviral and antimetastatic agents.
Patent FI-941709-A0 (FI)
Inventor: MOOSMANN WERNER
IPC: B43K11/00
Filed: 1994-04-13
Abstract: A refillable writing implement (1) has a writing tank (2) for supplying writing liquid to the nib (4). It has an additional storage tank (3), from which the writing tank (2) can be refilled via a connection acting as a valve (6). The storage tank (3) can be refilled from the outside via a valve with an associated refill container. The refill container has an injection needle with a valve, and means for subjecting the writing liquid in its interior to pressure. <IMAGE>
Patent FI-945227-A0 (FI)
Inventor: WAKIMASU MITSUHIRO
IPC: A61K38/00
Filed: 1994-11-07
Abstract: A cyclic hexapeptide represented by the formula:    cyclo[A-Asp(R<1>)-Y-NH-CHR<2>-CO-C-D-Trp(N<in>-R<3>)-]   (I> wherein A is a D-acidic- alpha -amino acid residue; Y is an acidic- alpha -amino acid residue; C is an L- alpha -amino acid residue; R<1> is a group represented by the formula: <CHEM> wherein X<1> and X<2> are independently H, C1-6 alkyl, C1-6 alkoxy, halogen or nitro, and may bind together to form a ring in cooperation with the adjacent carbon atom; R<2> is C1-6 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-3 alkyl, C1-6 alkylthio-C1-3 alkyl, C3-7 cycloalkylthio-C1-3 alkyl, C1-5 alkoxy-C1-3 alkyl, C3-7 cycloalkoxy-C1-3 alkyl, C1-6 alkylthio, C3-7 cycloalkylthio, C1-5 alkoxy or C3-7 cycloalkoxy; R<3> is H, C1-6 alkyl, C3-7 cycloalkyl, -COR<4>, - COOR<5> or -CONHR<6>; when X<1>, X<2> and R<3> are all hydrogen atoms, R<2> is not an isobutyl group, or a saalt thereof, which exhibits excellent antagonistic action against endothelin receptors, particularly endothelin B receptors.
Patent FI-945688-A0 (FI)
Inventor: ALIG LEO
IPC: C07C259/18
Filed: 1994-12-02
Abstract: Acetic acid derivatives of the formula <IMAGE> in which L, M, Q and T have the meaning stated in the description, can be used for the treatment or prophylaxis of diseases caused by the binding of adhesive proteins to blood platelets, and by aggregation of blood platelets and cell-cell adhesion. They are prepared by eliminating protective groups in corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitriles.
Patent FI-951003-A0 (FI)
Inventor: YANG BINGWEI V
IPC: A61K31/7042
Filed: 1995-03-03
Abstract: A compound having the formula     <IMAGE>  (IV)  wherein Z is CH2-N(CH3), N(CH3)-CH2, or    <IMAGE>   R1 and R2 are selected from 1) one of R1 and R2 is OH and the other of R1 and R2 is (C1-C6)alkyl, (C2-C6)alkenyl, or phenyl, with the proviso that Z is not CO; 2) one of R1 and R2 is H and the other of R1 and R2 is NR5R6 wherein R5 and R6 are independently selected from H and (C1-C6)alkyl, or is OR7 wherein R7 is H or (C1-C6)alkyl; and 3) R1 and R2 together form an oxo or oxime group; R3 and R4 are each hydroxyl or together form a carbonate or thiocarbonate group; and pharmaceutically acceptable salts thereof.
Patent FI-952712-A0 (FI)
Inventor: NOESKE-JUNGBLUT CHRISTIANE
IPC: A61K35/56
Filed: 1995-06-02
Abstract: PCT No. PCT/DE93/01172 Sec. 371 Date Aug. 24, 1995 Sec. 102(e) Date Aug. 24, 1995 PCT Filed Dec. 3, 1993 PCT Pub. No. WO94/13807 PCT Pub. Date Jun. 23, 1994The invention relates to a natural protein or a protein that can be synthetically produced, which is a thrombin inhibitor and can be isolated from the saliva of insects which suck the blood of mammals. Preferred is the Triatoma pallidipennis insect. The protein is used for the treatment of thromboses or unstable angina or arteriosclerosis, or for the prevention of a reblockage of vessels after PTCA/PTA or for the prevention of blood clotting in hemodialysis.
Patent FI-955702-A0 (FI)
Inventor: BOWDEN MARTIN CHARLES
IPC: C07C41/60
Filed: 1995-11-27
Abstract: A process for the preparation of a lower alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)- 2,2-dimethylcyclopropane carboxylic acid where lower alkyl means alkyl of up to four carbon atoms which comprises the steps of (a) reacting a compound of formula: CF3-CXCl-CH(OH)-CH=C(CH3)2 wherein X is chloro or bromo, with a tri-lower-alkyl orthoacetate containing up to four carbon atoms in each alkyl group in the presence of at least a catalytic amount of an active clay at an elevated temperature for a sufficient time to obtain a compound of formula: CF3-CXCl-CH=CH-C(CH3)2-CH2CO2R wherein R is an alkyl group containing up to four carbon atoms, and (b) treating said compound of formula (III) with at least one molar equivalent of a base to obtain said alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid.
Patent FI-960333-A0 (FI)
Inventor: FRITZ HANS
IPC: C12P21/02
Filed: 1996-01-24
Abstract: PCT No. PCT/EP94/02445 Sec. 371 Date Jan. 25, 1996 Sec. 102(e) Date Jan. 25, 1996 PCT Filed Jul. 25, 1994 PCT Pub. No. WO95/03333 PCT Pub. Date Feb. 2, 1995The present invention relates to novel inhibitors of human tryptase, to their isolation from leeches, to nucleotide sequences encoding the novel inhibtor molecules or fragments thereof, to vectors containing the coding sequence thereof, to host cells transformed with such vectors, to the recombinant production of the inibitors, to pharmaceutical compositions containing the novel inhibitor molecules, and to their use in diagnosis and therapy.
Patent FI-961699-A0 (FI)
Inventor: SOININEN PERTTI
IPC: C08K3/34
Filed: 1996-04-18
Abstract: A semiconducting floor covering which consists of a layer (2) of conductive material parallel to the surface of the covering and at least one layer (1, 3) of polyvinyl chloride based material adhered to the layer of conductive material. As plasticizer for the polyvinyl chloride in the floor covering, 2-ethyl hexyl diphenyl phosphate and aliphatic ester compound has been used or these two combined so that per 100 parts of polyvinyl chloride it contains 39-80 parts of plasticizer. It further contains 1-250 parts of talc and/or ATH as filler.
Patent IL-74423-A0 (IL)
Title: N-(1-substituted-4,5-dihydro-1 h-pyrazol-4-yl)benzamides,their preparation and pharmaceutical compositions containing them
IPC: A61P1/08
Filed: 1985-02-22
Abstract: N-(1-Substituted-4,5-dihydro-IH-pyrazol-4-yl) benzamides of general formula I.wherein R is loweralkyl, cycloalkyl or phenyl-loweralkyl and R, is hydroxy, cyano, nitro, amino, methylamino, dimethylamino, halo, trifluoromethyl, loweralkyl, loweralkoxy, sulphamoyl or acetamido, and when n is more than 1 up to 3, R, can be the same or different, have gastrokinetic and anti- emetic utility in animals. The compounds can be prepared by oxidation of 1,2-disubstituted-N-(4-pyrazolidinyl) benzamides with a metal hypochlorite.
Patent IL-87885-A0 (IL)
Title: Compounds having antiprogestational and anti-estrogenic activities for the treatment of tumours
IPC: A61K31/575
Filed: 1988-09-30
Abstract: Agents, containing at least one compound having antiprogestational activity and at least one compound having anti-estrogenic activity, are suitable for the treatment of hormone-dependent tumors.
Patent IL-88265-A0 (IL)
Title: Dual chambered mixing and dispensing device
IPC: A61J1/05
Filed: 1988-11-02
Abstract: A dual chambered vial is equiped with a dislodgeable stopper device (16) between the two chambers (9, 15), whereby components of a mixture may be maintained in separate chambers until comingling is desired. The stopper (16) is dislodged by means of a plunger (18) activated by depression of flexible walls (14) of one chamber.
Patent SE-9804614-A0 (SE)
Title: New peptides and use thereof
Inventor: MATTSBY-BALTZER INGER
IPC: C07K14/79
Filed: 1998-12-29
Abstract: The invention relates to new peptides formed of at least seven subsequent amino acids of the amino acids in position 12-40, counted from the N-terminal end, in the sequence constituting human lactoferrin, and preferably modifications thereof. The invention also relates to medicinal products comprising such peptides, especially intended for treatment and prevention of infections, inflammations and tumours. Furthermore, the invention relates to food stuff, e.g. infant formula food, comprising the above mentioned peptides.
Patent AU-PM922894-A0 (AU)
Title: Methods of and apparatus for laying turf
IPC: A01G1/00
Filed: 1994-11-04
Abstract: An apparatus, and related method, for laying sand and/or a sand reinforcement matrix onto a pre-prepared surface, includes an apparatus having a hopper for providing a matrix to be laid, a plunger at the forward end, in the sense of direction of movement of the apparatus, of the hopper and an element for reciprocating the plunger for taking material from the hopper and delivering it through an extrusion aperture in the rear thereof to an extrusion mold. The extrusion is effected by moving forwardly as pressure is applied to the matrix to be extruded and as the mold passes over the matrix. The extrusion of a sand, or a sand reinforcement, is compacted in the extrusion by using the weight of the apparatus against which the extrusion plunger acts together with the impaction of previously extruded material. The plunger moves forwardly so that material in the hopper can fall in front of the plunger; the plunger is moved rearwardly causing this material to move into the extrusion mold until compaction commences to take place, at which time compaction is increased until the pressure on the plunger is sufficient to physically cause the apparatus to move.
Patent FI-20030959-A0 (FI)
Inventor: DE GODZINSKY CHRISTIAN
IPC: F21Y115/10
Filed: 2003-06-27
Abstract: A LED operation light, comprising at least two power sources, at least one of which is an adjustable power source, at least two LED units, and measuring and control means. The LED units, which comprise one or more LED components, emit light in response to power received from the power source. The LED components have been arranged to produce emission of light color components of at least two different wavelengths. The measuring means have been arranged to measure light emission of the LED unit and, based on measurement data, to generate control information to be sent to the adjustable power source to adjust the magnitude of power to be supplied to the LED unit. The light emission of the LED component changes as the received power changes, which again results in a change in the correlation between the emitted light color components, and therefore in the color temperature.
Patent FI-20060549-A0 (FI)
Inventor: SNELLMAN RAIMO
IPC: A61B/
Filed: 2006-06-06
Abstract: The invention provides an apparatus, attachable to the body, for the measurement of breathing, which comprises a part (2) that is attached to the body, on which a casing (1) containing a measurement apparatus has been attached. The measurement apparatus in the casing (1) comprises an alarm part (8) and an electric circuit (7), which shuts on and off according to the breathing. The alarm part (8) alarms when the electric circuit shuts off. A delay unit (6) has been connected to the electric circuit (7), with which the alarm part (8) can be adjusted to alarm after a desired amount of time has passed since the electric circuit (7) shut off. The electric circuit (7) can advantageously be formed partly of a spring (3), with which the electric circuit (7) can be adjusted to a desired tension to alarm at a desired breathing situation.
Patent FI-20075911-A0 (FI)
Inventor: PHAN VINH VAN
IPC: H04Q/
Filed: 2007-12-14
Abstract: It is provided a solution for assigning to a relay node of a wireless telecommunication system an identifier from which a corresponding identifier of a central node associated with the relay node is derivable according to a determined rule. Accordingly, the identifiers of central nodes and their relay nodes are assigned in a manner which facilitates identification of a central node from a received relay node identifier, thereby avoiding the necessity of consulting higher layer controllers in order to identify the central node.
Patent FI-20095725-A0 (FI)
Inventor: POHJOLA KALLE
Filed: 2009-06-25
Abstract: In the method, a joint pin (10) is fastened in a removable manner to a first structural member (100), such as a shovel or the supporting part of a shovel in loading, mucking or excavating equipment. The structural member is provided with a conical recess (102) and a threaded fastening hole (104) at the bottom of the recess. The joint pin is provided with a conical fixing piece (14) that matches the recess, and a hole (12) extending in the direction of the longitudinal axis of the joint pin. The fixing piece is fitted in the recess of the first structural member and is fastened in its place by a fastening screw (20), wherein the fixing piece is pressed tightly into the recess. The joint pin is provided with a pin part encircled by an annular bearing (30) placed in a bearing hole (202) in a second structural member (200). The hole of the joint pin has an inner threading for engaging an extraction tool. The largest diameter of the fastening part is larger than the diameter of the pin part, wherein the joint pin to be extracted will remove the bearing (30) fitted around the pin part from the bearing hole (202).
Patent IL-104135-A0 (IL)
Title: Process for the manufacture of halomaleic and halofumaric esters
IPC: C07C67/317
Filed: 1992-12-17
Abstract: There is provided a method of manufacture of dialkyl monohalomaleate and dialkyl monohalofumarate and mixtures thereof via a dehydrohalogenation of the appropriate dialkyl dihalosuccinate precursor in the presence of an aqueous base and a phase transfer catalyst.
Patent IL-115047-A0 (IL)
Title: Pneumococcal polysaccharide - recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections.
IPC: A61K39/09
Filed: 1995-08-23
Abstract: Immunogenic polysaccharide-protein conjugates are generated which have an oxidized polysaccharide derived from the capsular polysaccharide of Streptococcal pneumniae and the pneumolysin protein of S. pneumoniae which is expressed recombinantly. The pneumolysin is not toxoided prior to conjugation with said oxidized polysaccharide. The immunogenic conjugates are used as vaccines to elicit antibody responses to the capsular polysaccharide of S. pneumoniae and to recombinant pneumolysin, and to immunize against S. pneumoniae-caused disease.
Patent IL-132601-A0 (IL)
Title: Phthalocyanine and use of phthalocyanine as a marking agent
IPC: C09B47/067
Filed: 1998-05-13
Abstract: Phthalocyanines of the formulawhereMe is twice hydrogen, twice lithium, magnesium, zinc, copper, nickel, VO, TiO, AlCl, AlOH, AlOCOCH3, AlOCOCF3, SiCl2 or Si(OH)2,at least four of the radicals R1 to R16 are each independently of the others a five- or six-membered saturated nitrogen-containing heterocyclic radical which is bonded to the phthalocyanine structure via a ring nitrogen atom and which can additionally contain further hetero atoms, andany remaining radicals R1 to R16 are each hydrogen, halogen, hydroxysulfonyl or C1-C4-dialkylsulfamoyl,subject to the proviso that tetrakispiperidinylphthalocyanine shall be excluded,and heterocyclyl-substituted phthalocyanines are useful for marking liquids, in particular mineral oils.
Patent IL-147794-A0 (IL)
Title: Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
IPC: A61K9/20
Filed: 2000-08-16
Abstract: Modafinil is effective in improving symptoms of attention deficit hyperactivity disorder and symptoms of multiple sclerosis fatigue. The administration of modafinil is also shown to activate the tuberomamillary neurons of the posterior hypothalamus, and thus exhibits activity in an area of the brain associated with normal wakefulness functions.
Patent IL-161390-A0 (IL)
Title: Ready-to-use- paracetamol injection solutions containing propylene glycol as the only cosolvent
IPC: A61K9/00
Filed: 2002-10-15
Abstract: The present invention refers to ready-to-use highly stable paracetamol injectable solutions, prepared by mixing paracetamol, water, propylene glycol, and a citrate buffer. (pH 4.5 to 6.5), and by heating said solution under preset conditions. The resulting solution may be stored for an extended period of time within a wide range of temperatures, with no paracetamol precipitation and/or its chemical modification.
Patent IL-169439-A0 (IL)
Title: Fluoroalkoxy-substituted 1,3 - dihydro-isoindolyl compounds and their pharmaceutical uses
IPC: A61K31/4709
Filed: 2005-06-28
Abstract: The invention encompasses novel compounds, pharmaceutically acceptable salts, hydrates, solvates, clathrates, enantiomers, diastereomers, racemates, or mixtures of stereoisomers thereof, pharmaceutical compositions of these compounds, and methods of using these compounds and compositions in mammals for treatment or prevention of diseases associated with PDE4.