baber/WOPTO huggingface dataset:
Patent CA-2907676-C (CA)
Inventor: BOGER DALE L
IPC: C07D413/14
Filed: 2014-03-20
Granted: 2017-11-07
Abstract: The invention relates to a cyclic N-acyl O-amino phenol CBI  derivative represented by Formula I: (see formula I) wherein: R is hydrido or a C1-C6 hydrocarbyl; and R3 is: ( see R3 formula 1); (see R3 formula 2); (see R3 formula 3); (see R3 formula 4); (see R3 formula 5); and (see R3 formula 6) wherein: R4 is: (see R4 formula 1); (see R4 formula 2); (see R4 formula 3); (see R4 formula 4); (see R4 formula 5); and (see R4 formula 6) R5, R6, R7 and R8 are each independently -H, -OH, -O (C1-C6 hydrocarbyl), C1-C6 hydrocarbyl or halogen; and R9 is -H, -C(O)O(C1-C6 hydrocarbyl), -C(O) (C1-C6 hydrocarbyl), -C(O)NH2, -C(O)NHNH2, or -C(O)NHNHC(O)O(C1-C6 hydrocarbyl).  The compounds have been shown to be pro-drugs, subject to reductive activation by cleavage of a N-0 bond, effectively releasing the free drug in functional in vitro cellular assays for cytotoxic activity approaching the activity of the free drug, yet remain essentially stable to ex vivo DNA alkylation conditions.
Patent CA-2908431-C (CA)
Inventor: ZIMMERMANN AUGUSTO J PEREIRA
IPC: F25B9/00
Filed: 2015-10-07
Granted: 2021-05-18
Abstract: The present application provides a carbon dioxide based refrigeration system. The carbon dioxide based refrigeration system may include a mid temperature cycle with a mid temperature ejector, a low temperature cycle with a low temperature ejector, and a gas cooler/condenser in communication with the mid temperature cycle and the low temperature cycle.
Patent CA-2910148-C (CA)
Title: Implants pour induire l'integration des tissus mous et durs
Inventor: MONJO CABRER MARTA
IPC: A61L27/06
Filed: 2013-04-18
Granted: 2020-08-18
Abstract: La présente invention concerne un implant biocompatible comprenant un ou plusieurs métal (aux), alliage (s) métallique (s), oxyde (s) métallique (s) ou une combinaison de ceux-ci, un composé antioxydant choisi dans le groupe constitué par flavonoïdes ou methoxytryptophols, un ester associé, un sel pharmaceutiquement acceptable associé ou une combinaison de ceux-ci, étant revêtus sur moins une partie d'une surface de métal, d'alliage métallique ou d' oxyde métallique dudit implant biocompatible. Cet implant est utile pour remplacer un tissu osseux chez des animaux vertébrés, et en outre de restaurer la fonction normale dudit tissu, principalement en raison de sa capacité d'induire une intégration osseuse et une fixation de tissus mous.
Patent CA-2921047-C (CA)
Title: Deployable reflectarray antenna structure
Inventor: HARVEY THOMAS J
IPC: H01Q1/08
Filed: 2016-02-16
Granted: 2023-09-19
Abstract: The invention is directed to deployable reflectarray antenna structure. In one embodiment, the deployable reflectarray antenna structure includes a pair of flexible electrical elements, a feed antenna, and a deployment mechanism that employs a plurality of tapes to respectively transition the pair of flexible electrical elements from an undeployed state in which the elements are folded towards a deployed state in which the deployment mechanism and electrical elements cooperate to form a reflectarray and a subreflector of a reflectarray antenna structure. Further, the deployment mechanism also operates to position the reflectarray and subreflector relative to one another and to the feed antenna so as to realize a reflectarray antenna structure.
Patent CA-2933508-C (CA)
Title: Modified serpins for the treatment of bleeding disorders
Inventor: HUNTINGTON JAMES ANDREW
IPC: C07K14/81
Filed: 2014-12-15
Granted: 2021-04-06
Abstract: This invention relates pro-coagulant serpin molecules engineered by modification of the P4, P2, P1 and/or P1' residues within the reactive center loop (RCL) to display increased specificity for anticoagulant proteases. These modified serpin molecules may be useful in therapy, for example as pro-coagulants for the treatment of bleeding.
Patent CA-2935390-C (CA)
Inventor: ARIARATNAM SAMUEL
IPC: E21B7/04
Filed: 2014-01-03
Granted: 2021-08-03
Abstract: L'invention concerne un procédé et un appareil de forage directionnel qui utilisent des détecteurs d'onde mécanique et un train de tiges de forage comportant un trépan à une extrémité trépan du train de tiges de forage. Pendant une opération de forage souterrain dans une formation souterraine, un signal d'onde mécanique est transmis en utilisant un émetteur d'onde mécanique disposé à l'extrémité du trépan du train de tiges de forage. Le signal d'onde mécanique est reçu par un réseau de récepteurs d'onde mécanique au niveau de la surface du sol au-dessus de la formation souterraine. Les signaux d'onde mécanique reçus sont traités afin de déterminer au moins l'emplacement du trépan dans la formation souterraine. Les données de position et de sens de déplacement sont transmises à une unité de commande de forage.
Patent CA-2935734-C (CA)
Title: Catheter assemblies having a protective lubricious sleeve
Inventor: O'FLYNN PADRAIG M
IPC: A61M25/01
Filed: 2015-01-08
Granted: 2020-01-14
Abstract: A catheter assembly(lO) includes a protective tip (14) defining an interior chamber (20) between its proximal and distal ends. A protective lubricious sleeve (24) is positioned within the interior chamber. A catheter (12) of the assembly is configured to be advanced proximally into and through the interior chamber to position at least a portion of the catheter within the protective sleeve, with the protective sleeve being retained upon the catheter as at least a proximal portion of the catheter exits the proximal end of the protective tip and is advanced through a body lumen. A second sleeve (106) may be associated with the protective tip and configured to extend distally from the protective tip to remain outside of the body lumen during use and receive a more distal portion of the catheter.
Patent CA-2936877-C (CA)
Title: Neutralizing human monoclonal antibodies against hepatitis b virus surface antigen
Inventor: MONDELLI MARIO UMBERTO FRANCESCO
IPC: A61P31/14
Filed: 2015-01-15
Granted: 2023-03-28
Abstract: The invention is in the field of medical treatment and prevention. The invention provides an antibody or a part thereof capable of specifically binding to the Hepatitis B surface antigen (HBsAg) and having Hepatitis B Virus (HBV) neutralizing activity, wherein said antibody or fragment thereof comprises a light chain CDR1 region comprising the amino acid sequence of SEQ ID NO: 5, a light chain CDR2 region comprising the amino acid sequence of SEQ ID NO: 6, a light chain CDR3 region comprising the amino acid sequence of SEQ ID NO: 7, a heavy chain CDR1 region comprising the amino acid sequence of SEQ ID NO: 8, a heavy chain CDR2 region comprising the amino acid sequence of SEQ ID NO: 9 and a heavy chain CDR3 region comprising the amino acid sequence of SEQ ID NO: 10.
Patent CA-2942093-C (CA)
Inventor: ALVAREZ MONTANER LLUIS
IPC: B64D1/16
Filed: 2015-03-12
Granted: 2019-09-10
Abstract: L'invention concerne un dispositif extincteur d'incendies à usage aérien qui utilise un réservoir avec deux récipients indépendants et reliés entre eux, d'eau et d'un mélange spumogène, conjointement à une chambre de génération de mousse d'extinction. Le dispositif comprend des moyens électroniques de commande de ses fonctions, des moyens de déversement de la mousse d'extinction formée qui permettent tant le vidage rapide que la diffusion dans une zone étendue, ce qui permet de réaliser divers services de déchargement à volonté.
Patent CA-2950467-C (CA)
Inventor: BENJELLOUN MLAYAH BOUCHRA
IPC: C12P19/02
Filed: 2015-06-03
Granted: 2022-12-06
Abstract: La présente invention concerne un procédé de production d'éthanol, comprenant les étapes de prétraitement de la matière première végétale lignocellulosique, comprenant les étapes consistant à déstructurer la matière première végétale lignocellulosique, puis à séparer, d'une part, la cellulose (C6) apte à être ensuite hydrolysée (et fermentée pour produire de l'éthanol) et, d'autre part, les hémicelluloses aptes à être ensuite hydrolysées et les lignines, caractérisées en ce que l'hydrolyse de la cellulose et des hémicelluloses est ensuite effectuée de manière séquencée selon les étapes suivantes consistant à : -i) commencer l'hydrolyse enzymatique de la cellulose au moyen d'au moins une enzyme pendant une première période en vue d'obtenir un hydrolysat intermédiaire; -ii) ajouter les hémicelluloses audit hydrolysat intermédiaire; -iii) poursuivre l'hydrolyse enzymatique du mélange jusqu'à ce qu'un hydrolysat final soit obtenu au bout d'une période totale d'hydrolyse enzymatique.
Patent CA-2950622-C (CA)
Title: Press-fit bearing locking system, apparatus and method
Inventor: NOWITZKI WESLEY JOHN
IPC: F04D13/08
Filed: 2016-12-01
Granted: 2020-01-07
Abstract: A press-fit bearing locking system, apparatus and method are described. A press-fit bearing locking system includes a diffuser having a diffuser groove on an inner diameter (ID), a bushing comprising an outer diameter (OD) press-fit into the grooved ID of the diffuser, the OD of the bushing having a bushing groove tracing a path of the diffuser groove, and a high thermal expansion material (HTEM) key seated within the bushing groove. A press-fit bearing locking method includes seating a HTEM key inside a groove on an OD of a bushing, press-fitting the bushing with HTEM key into a diffuser such that the bushing groove is opposite a groove on an ID of the diffuser, operating an electric submersible pump assembly including the diffuser during a temperature rise, and allowing the HTEM key to expand into the diffuser groove during the temperature rise to lock the bushing against the diffuser.
Patent CA-2953393-C (CA)
Title: Dispositif d'injection de medicament automatique ayant une indication visible de progression d'injection
Inventor: DENNIS JOSEPH DANIEL
IPC: A61M5/315
Filed: 2015-08-07
Granted: 2019-05-14
Abstract: L'invention concerne un dispositif d'injection de médicament automatique (20) comprenant des indicateurs de progression d'injection (82-85) visibles le long d'une périphérie du boîtier de dispositif (23). Les indicateurs de progression d'injection comprennent un élément de drapeau (100) qui est mobile à mesure qu'un mécanisme d'entraînement (60) du dispositif avance un piston d'étanchéité (58) à l'intérieur d'un récipient de médicament (50). Les indicateurs de progression d'injection sont configurés pour indiquer séquentiellement, pendant une injection unique, lorsque l'élément de drapeau se déplace pour indiquer de façon coopérative différents indicateurs de progression d'injection à différents moments pendant l'injection unique, la progression d'injection de l'injection pouvant être surveillée par un utilisateur.
Patent CA-2962959-C (CA)
Inventor: BRISTOL ANDREW
IPC: C12N9/86
Filed: 2015-10-08
Granted: 2023-04-04
Abstract: The present invention provides, in part, formulations comprising a beta-lactamase. Particularly, modified-release formulations comprising a beta-lactamase are provided which release a substantial amount of the beta-lactamase in the intestines. Therapeutic uses of the beta-lactamase formulations are also provided.
Patent CA-2963156-C (CA)
Title: Updating damaged-enhanced 3d polygon meshes
Inventor: LAGACE MICHEL
IPC: G06T17/20
Filed: 2014-09-30
Granted: 2020-02-11
Abstract: A method and computer system for updating damaged-enhanced polygon meshes in a computer simulation associated to a storage module accessible to at least a first and a second decentralized simulation stations and a centralized processing unit thereof. At the first station, during the computer simulation, determining coordinates of a virtual impact on a 3D polygon mesh, computing newly formed 3D polygon mesh(es) from the virtual impact without updating the storage module and rendering damaged-enhanced image(s) of the newly formed 3D polygon mesh(es) for display from a first field of view of the first station. At the second station, receiving the coordinates of the virtual impact. At the centralized processing unit, receiving the coordinates of the virtual impact, computing the newly formed 3D polygon mesh(es) from the received coordinates independently from the first station, in non-real-time priority processing and persistently updating the storage module with newly formed 3D polygon mesh(es).
Patent CA-2968804-C (CA)
Title: Systeme de domotique et de conciergerie et methode destines a une communaute
Inventor: POULIN JEAN-PIERRE
IPC: G06Q30/06
Filed: 2017-05-31
Granted: 2022-08-30
Abstract: La présente invention concerne un système et un procédé dautomatisation et de conciergerie domestiques pour une communauté. Un utilisateur peut accéder à une interface pour commander des systèmes et dispositifs domestiques ou utiliser le service de conciergerie pour acheter des biens et des services disponibles pour une livraison à domicile.
Patent CA-2971921-C (CA)
Title: Heterogeneous membrane electrodes
Inventor: LAUKS IMANTS
IPC: B01L3/00
Filed: 2005-06-01
Granted: 2020-01-07
Abstract: The present invention relates to planar electrochemical sensors with membrane coatings used to perform chemical analyses. The object of this invention is to provide unit-use disposable sensors of very simple and inexpensive construction, preferably with only a single membrane coating on an electrode.  The invented devices are potentiometric salt-bridge reference electrodes and dissolved gas sensors constructed with a heterogeneous membrane coating of a conductor.  The heterogeneous membrane, which is an intimate admixture of a hydrophobic and a hydrophilic compartment, concurrently supports constrained transport of non-volatile species through its hydrophilic compartment and rapid gas and water vapor transport through its hydrophobic compartment.
Patent CA-2972024-C (CA)
Title: Rail handbrake with prolonged release
Inventor: SAUTER JEFFREY F
IPC: B61H7/10
Filed: 2015-01-09
Granted: 2019-07-02
Abstract: A prolonged release system having a locking member pivotally mounted on a post within a hand brake and having an arm that contacts a clutch assembly to prevent the clutch assembly of the handbrake from engaging after it has been manually released. Rotation of the hand brake wheel causes a pawl on a ratchet gear to move into contact with a cam of the locking member so that the arm of the locking member moves out of contact with the clutch assembly. By maintaining the clutch assembly in a released position, the prolonged release system ensures that the brake chain drum is decoupled from the driveshaft of the hand brake and prevents the inadvertent application of the brakes. When a user turns the hand brake wheel, the locking member is disengaged from the clutch assembly and the hand brake can be set by a user.
Patent CA-2974331-C (CA)
Title: Downhole communications using selectable frequency bands
Inventor: ROBERSON MARK W
IPC: E21B47/12
Filed: 2015-03-11
Granted: 2019-10-29
Abstract: A system that is positionable in a wellbore in a subterranean formation can include a first transceiver that is positionable external to a casing string in the wellbore. The first transceiver can wirelessly transmit data via a signal within a frequency band that is selected based on a fluid property of a fluid in the wellbore and a property of the subterranean formation. The system can also include a second transceiver that is positionable externally the casing string and operable to receive the signal.
Patent CA-2976935-C (CA)
Title: Drug delivery device with vacuum assisted securement and/or feedback
Inventor: MCCULLOUGH ADAM B
IPC: A61M5/142
Filed: 2016-02-17
Granted: 2020-03-10
Abstract: A drug delivery device includes a housing having a rigid base with a surface defining at least one pressure communication channel or aperture, which distributes a negative fluid pressure across the base that draws the tissue against the base. The device may further include a porous, adhesive layer disposed over the pressure communication channel(s) or aperture(s), for adhesively attaching the device to tissue, which distribute a negative fluid pressure across the adhesive layer, to draw the tissue against the adhesive layer. The device may further include a pressure sensor for determining whether the device is properly attached to the body tissue by the adhesive layer. Further, at least one bladder may be used instead of the porous, adhesive layer for adhesively attaching the device to tissue. The bladder, in a partially inflated or expanded state, can apply constant pressure across the contact surface as it conforms to the contour of the tissue when the device is applied to the tissue thereby causing a flexible adhesive layer attached to the bottom thereof to conform to the contour of the tissue and adhere thereto. The subsequent evacuation of the bladder causes it to deflate and collapse or retract against the base, thereby causing the flexible adhesive layer, which is adhered to the tissue, to pull the tissue toward the base, thereby stretching the tissue.
Patent CA-2979220-C (CA)
Inventor: YANG JUN
IPC: B02C19/00
Filed: 2016-03-10
Granted: 2023-03-14
Abstract: La présente invention concerne un procédé de formation d'une composition par le co-traitement d'agrégats de nanocarbone et d'agrégats de noir de carbone, qui comprend la fourniture d'agrégats de nanocarbone, la fourniture d'agrégats de noir de carbone, et le mélange les agrégats de nanocarbone et des agrégats de noir de carbone de sorte que les agrégats de nanocarbone soient dispersés en agrégats de nanocarbone et agrégats de noir de carbone plus meubles, ou en nanocarbones individualisés dispersés parmi les agrégats de noir de carbone.
Patent CA-2983804-C (CA)
Title: Disposable microfluidic cartridge
Inventor: WILD ANDRE
IPC: B01F15/02
Filed: 2016-04-28
Granted: 2021-08-17
Abstract: The present disclosure is directed towards a disposable microfluidic cartridge configured for use in a system for the small scale production of nanoparticles used in scientific research or therapeutic applications. The system can be used to produce a wide variety of nanoparticles, including but not limited to lipid and polymer nanoparticles, carrying a variety of payloads. The system provides for a simple workflow which in certain embodiments can be used to produce a sterile product.
Patent CA-2986944-C (CA)
Inventor: CHRIST ARMIN
IPC: F15B11/036
Filed: 2016-05-24
Granted: 2019-07-16
Abstract: Relates to a cylinder unit comprising a rod and a housing, wherein the rod is guided on the housing so as to be displaceable along an adjustment axis, wherein a piston is fixed to the rod, which piston divides the interior space of the housing into a first chamber and a second chamber, wherein the housing has a safety outlet, wherein the safety outlet is arranged such that the piston closes off the safety outlet in fluid-tight fashion when the rod is in a zero position.
Patent CA-3003898-C (CA)
Title: Privacy lock
Inventor: MORSE THOMAS P
IPC: E05B65/10
Filed: 2016-10-27
Granted: 2023-10-24
Abstract: A privacy lock assembly and method of operation are provided. The lock assembly has a push button offset from the central axis of the lock assembly for locking and unlocking the assembly. The lock assembly includes compression springs to maintain integrated handles in predetermined orientations when the handles are not subject to a load.
Patent CA-3004665-C (CA)
Inventor: WU SAREINA CHIUNG-YUAN
IPC: A61K48/00
Filed: 2016-12-12
Granted: 2021-08-24
Abstract: An in vitro method for integrating an exogenous DNA sequence into the genome of a cell using a transposon system. The transposon system includes a first vector carrying inverted repeat sequences and an exogenous DNA, and a second vector that expresses a transposase. Also provided is a kit including the transposon system for integrating an exogenous DNA into the genome of a cell. A method for treating a subject is described that includes engineering an immune cell to carry an exogenous DNA sequence using the method and/or the kit described above and administering an effective amount of the engineered immune cell to the subject.
Patent CA-3006956-C (CA)
Inventor: PIERRE FRITZ
IPC: F25J1/02
Filed: 2016-11-10
Granted: 2020-10-27
Abstract: A method for producing liquefied natural gas (LNG). A natural gas stream is directed to a mechanical refrigeration unit to liquefy the natural gas stream and form a pressurized liquefied natural gas (LNG) stream with a pressure greater than 50 psia (345 kPa) and less than 500 psia (3445 kPa). A liquid refrigerant subcooling unit is provided at a first location. Liquid refrigerant is produced at a second location that is geographically separate from the first location. The produced liquid refrigerant is transported to the first location. The pressurized LNG stream is subcooled in the liquid refrigerant subcooling unit by exchanging heat between the pressurized LNG stream and at least one stream of the liquid refrigerant to thereby produce an LNG stream.
Patent CA-3009319-C (CA)
Inventor: VAN GIEL FRANS
IPC: C08J9/00
Filed: 2016-07-15
Granted: 2022-08-09
Abstract: The present invention provides a covering panel, such as a floor panel, wall panel or ceiling panel, comprising at least one substrate and optionally a top layer, whereby said substrate comprises a synthetic material and at least one filler material. The at least one filler is present i n an amount of at least 20.0 wt.% based on the weight of the substrate, and said filler material comprises at least 50 wt.% talc.
Patent CA-3021187-C (CA)
Title: Procede et systeme de generation de puissance auxiliaire
Inventor: AMIGO ANDREW
IPC: H02P9/04
Filed: 2016-04-29
Granted: 2023-06-27
Abstract: L'invention concerne un système de puissance auxiliaire pour un véhicule à moteur qui inclut un générateur de puissance qui génère de l'électricité pour charger une ou plusieurs batteries du système de puissance auxiliaire. Le véhicule à moteur inclut un moteur et un train d'entraînement qui distribue la puissance du moteur aux roues d'entraînement. Le train d'entraînement peut inclure une transmission, un arbre d'entraînement et un différentiel qui raccorde le moteur aux roues d'entraînement. Le générateur de puissance peut être raccordé au train d'entraînement (par ex., la transmission, l'arbre d'entraînement ou le différentiel) pour extraire une puissance pour générer de l'électricité ainsi que pour appliquer des charges de freinage sur les roues d'entraînement pour accroître la capacité à arrêter le véhicule à moteur.
Patent CA-3025255-C (CA)
Title: Fenetre composite de securite ecoenergetique
Inventor: WANG SHUQUAN
IPC: E06B3/66
Filed: 2018-11-26
Granted: 2021-01-12
Abstract: Une fenêtre composite de sécurité écoénergétique comprend un châssis latéral périphérique et une vitre installée sur le châssis, qui est fait dune structure composite. Un tuyau rectangulaire en métal à haute résistance est situé de manière centrale pour servir de corps principal du châssis latéral et une cavité de ce tuyau est remplie de matériau de remplissage. Plusieurs profils non métalliques sont respectivement fixés sur une surface extérieure du tuyau rectangulaire en métal à haute résistance et une rainure pour linstallation de la vitre est formée entre le tuyau et le profil non métallique. Un profil externe est fait dun alliage métallique, dun matériau de bois, dun matériau de plastique ou dun matériau de verre fixé sur une surface extérieure du profil non métallique. Le rendement des fenêtres externes de bâtiments, par exemple en matière disolation thermique, de préservation de la chaleur, déconomie dénergie, disolation acoustique et de résistance à la pression éolienne, est amélioré.