baber/WOPTO huggingface dataset:
Patent CA-3122098-A1 (CA)
Title: Topical, isotonic compositions for genital use
Inventor: ELLINGTON JOANNA E
IPC: A61P15/00
Filed: 2019-12-10
Abstract: The present disclosure provides compositions and methods for using topical, isotonic compositions comprising a prebiotic oligosaccharide, a metal co-factor, and an essential oil comprising bornyl acetate. The compositions support the genital microbiota and are useful for, for example, hydrating, lubricating, cleaning, and/or decreasing irritation or inflammation of the urogenital and/or anogenital region of a subject, and/or enhancing the beneficial genital microbiota of a subject. Such compositions are useful before, during, and/or after sexual and/or reproductive activity.
Patent CA-3122966-A1 (CA)
Title: Apparatus for forming a channel in a workpiece
Inventor: PIKARSKI DANIEL
IPC: B23B41/00
Filed: 2021-06-23
Abstract: Abstract The invention relates to apparatus for the formation of a channel in a workpiece located at a first face of a base of the body of the apparatus, said channel formed by a drill assembly of the apparatus connected to drive means located on a second opposing side of the said base, said drill assembly and drive means mounted so as to be movable in a guided manner with respect to said base. The movement is achieved by manual movement of a gripping means of an actuation means of the apparatus with respect to said base, so as to cause one or more flexible connecting members of the actuation means which are positioned intermediate the said gripping means and drill assembly to move and advance the said drill assembly towards the said workpiece. The channel is formed in accurate manner which then allows the same to receive securing means typically to allow a joint between first and second workpieces to be accurately formed. Date Recue/Date Received 2021-06-23
Patent CA-3123251-A1 (CA)
Inventor: DAEP CARLO
IPC: A61Q11/02
Filed: 2019-12-17
Abstract: Methods of reducing total pathogenic oral bacteria load within an individual's oral cavity are disclosed. Methods of selectively promoting growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria in a population of bacteria that comprises beneficial oral bacteria and pathogenic oral bacteria, such as in an individual's oral cavity, are disclosed. Methods of selectively promoting growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria in biofilm that comprises beneficial oral bacteria and pathogenic oral bacteria, including biofilm in an individual's oral cavity, are also disclosed, Methods of identifying a compound or composition that enhances the selective promotion of growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria by arginine and methods of identifying a compound or composition that enhances the selective promotion of growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria in biofilm by arginine are disclosed.
Patent CA-3123763-A1 (CA)
Inventor: HECHT GIL
IPC: B23C5/08
Filed: 2019-12-30
Abstract: A rotary milling tool (20) has a tool holder (22, 122) and a milling head (24) releasably attached thereto. The milling head (24) has a plurality of angularly spaced apart peripherally disposed cutting edges (32) which form an effective cutting edge (38). The milling head (24) has a head through recess (44) opening out to the head forward and rearward surfaces (26, 28). The recess (44) includes a centering region (52) and a driven region (54), the driven region (54) being axially forward of, and non-identical to, the centering region (52). The driven region (54) has at least one driven surface (58) facing opposite a rotational direction (R). The centering region (52) has at least one radially inwardly facing radial centering surface (62) located axially rearward of, and radially outward from, the at least one driven surface (58). The two opposing extremities (38a, 38b) of the effective cutting edge (38) define two parallel planes (PF, PR) respectively between which both the at least one driven surface (58) and the at least one radial centering surface (62) are disposed.
Patent CA-3124195-A1 (CA)
Title: Fusion protein with a toxin and scaffold protein
Inventor: STEYAERT JAN
IPC: C07K14/435
Filed: 2019-12-20
Abstract: The present invention relates to the field of structural biology and drug discovery. More specifically, the present invention relates to novel fusion proteins, their uses and methods in three-dimensional structural analysis of macromolecules, such as X-ray crystallography and high-resolution Cryo-EM, and their use in structure-based drug design and screening, and as pharmacological tools. Even more specifically, the invention relates to a functional fusion of a toxin and a scaffold protein wherein the folded scaffold protein interrupts the topology of the toxin by insertion in an exposed ß-turn of a ß-strand-containing domain of said toxin to form a rigid fusion protein that retains its high affinity target binding capacity.
Patent CA-3124280-A1 (CA)
Title: Ocular compositions
Inventor: THAKUR RAGHU RAJ SINGH
IPC: A61P27/00
Filed: 2019-12-20
Abstract: The present invention relates to ocular compositions for the controlled release of a therapeutic agent. The ocular composition comprises at least 20% w/w of a therapeutic agent; 5 to 75% w/w of a photopolymerizable composition selected from the group consisting of fragments or monomers of polyalkylene glycol mono-acrylate, polyalkylene glycol diacrylate, polyalkylene glycol methacrylate and polyalkylene glycol dimethacrylate, and mixtures, copolymers, and block copolymers thereof.; 0.1 to 40% w/w of a biodegradable polymer selected from the group consisting of lactide/glycolide copolymer (including poly(lactide-co-glycolide) (PLGA)), poly (L-lactide) (PLA), polyhydroxyalkanoates, including polyhydroxybutyrate, polyglycolic acid (PGA), polycaprolactone (PCL), poly (DL-lactide) (PDL), poly (D-lactide), lactide/caprolactone copolymer, poly-L-lactide-co-caprolactone (PLC) and mixtures, copolymers, and block copolymers thereof; and a photoinitiator.
Patent CA-3124346-A1 (CA)
Title: Systems and methods for generating recommendations using a corpus of data
Inventor: MERZ CHRISTOPHER JOHN
IPC: G06Q30/0251
Filed: 2016-12-09
Abstract: A method and system for recommending a merchant are provided. The method includes receiving financial transaction data documenting financial transactions between a plurality of account holders and a plurality of merchants and generating a merchant correspondence matrix that includes the plurality of merchants and a plurality of indicators of interactions associated with pairs of the plurality of merchants. The plurality of indicators of interactions tallying financial transactions conducted by the plurality of account holders at both of the merchants in a pair of the plurality of merchants. The method further includes receiving a query for a recommendation of a merchant from an account holder and generating a ranked list of merchants based on a recommender algorithm. The recommender algorithm inferring user preferences from attributes of the plurality of merchants that were visited by the cardholder.
Patent CA-3127570-A1 (CA)
Title: Desired departure temperature for a battery in a vehicle
Inventor: MUNIZ THOMAS
IPC: B60L50/60
Filed: 2019-02-21
Abstract: A desired departure temperature is determined for a battery, having a temperature, in a vehicle based at least in part on trip information associated with a trip. A temperature controlling system is used to bring the temperature of the battery towards the desired departure temperature, wherein the vehicle begins the trip with the battery at the desired departure temperature.
Patent CA-3129892-A1 (CA)
Title: Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
Inventor: EISENBACH-SCHWARTZ MICHAL
IPC: A61P25/28
Filed: 2015-03-12
Abstract: A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session.
Patent CA-3132414-A1 (CA)
Title: Immunomodulating mesenchymal stem cells
Inventor: SPAAS JAN
IPC: C12N5/0775
Filed: 2020-03-12
Abstract: The current invention concerns an isolated mesenchymal stem cell wherein said cell is measuredpositive for mesenchymal markers CD29, CD44 and CD90; and negative for MHC class II molecules,whereinsaid cell secretes immunomodulatory prostaglandin E2 cytokine when present in an inflammatory environment or condition.The current invention also concerns a cell composition comprising said cells and the use thereof in the treatment of immune-related diseases and inflammatory conditions.
Patent CA-3132490-A1 (CA)
Inventor: COOK STEPHEN D
IPC: A61F2/34
Filed: 2021-09-30
Abstract: A total hip replacement prosthesis that comprises an acetabular component and a femoral component. The acetabular component has a full or partial hemispherical shape, and comprises a shell and one or more magnets. The femoral component comprises a stem portion comprising a proximal end and a distal end, a neck portion comprising a tapered end and a base end that is joined to the proximal end of the stem portion, and a spherical head that is affixed to the tapered end of the neck portion and comprises one or more magnets. The acetabular component is configured to receive all or a portion of the spherical head of the femoral component.  Further, the one or more magnets of the acetabular component and the one or more magnets of the spherical head of the femoral component are oriented to generate an attractive force therebetween.
Patent CA-3133599-A1 (CA)
Title: Formulations de cafeine a liberation pulsee et leur procede de preparation
Inventor: ACHARYA MANUTOSH
IPC: A61K9/20
Filed: 2020-04-28
Abstract: La présente invention concerne des formulations de caféine à libération pulsée comprenant des systèmes particulaires de caféine préparés en utilisant des agents retardateurs de libération et au moins un ou plusieurs excipients de qualité alimentaire. La présente invention concerne également le procédé de préparation de formulations de caféine, une pluralité de systèmes particulaires combinés pour obtenir la formulation de caféine à libération pulsée comprenant des agents retardateurs de libération, qui assurent une libération de caféine par impulsions dans des conditions physiologiques différentes. La formulation de caféine à libération pulsée est préparée sous la forme de comprimés, de gélules, de capsules molles, de caplets, de suspensions huileuses ou mélangée avec des compléments alimentaires pour une administration chez des sujets. Les formulations de caféine telles que décrites ici libèrent la caféine sur la totalité du tractus gastro-intestinal par impulsions au cours d'une période de 2 à 8 heures et peuvent être administrées à des sujets pour renforcer leur énergie, améliorer leur concentration, leur santé cardiovasculaire et à des fins de perte de poids.
Patent CA-3134283-A1 (CA)
Title: Adjustable lever for a centrifugal actuator of a continuously variable transmission drive pulley
Inventor: LASKO JEFFERY WADE
IPC: F16H9/12
Filed: 2021-10-14
Abstract: The present disclosure pertains to an adjustable lever for a centrifugal actuator of a continuously variable transmission drive pulley, the adjustable lever including a first extension and a second extension each for receiving a removable weight. The present disclosure also provides kits comprising an adjustable lever as disclosed herein and at least one first removable weight, at least one second removable weight, or both.
Patent CA-3138129-A1 (CA)
Inventor: GERVAIS DARREN
IPC: E21F16/02
Filed: 2021-11-03
Abstract: A dewatering pump support apparatus configured to buoyantly suspend a dewatering pump in a body of water in which all or some is desired to be removed. The dewatering pump support apparatus includes a main housing having at least one wall and a bottom configured to form an interior volume having an opening thereto. The main housing includes an upper perimeter edge wherein the upper perimeter edge includes flotation members secured thereto. The flotation members are circumferentially disposed around the main housing and provide buoyancy for the dewatering pump support apparatus. A strainer assembly is integrally secured to the main housing. The strainer assembly extends outward from the housing and includes a plurality of walls having a multitude of apertures formed therein. The strainer assembly further includes a flotation member and additionally can be configured with a slot allowing air into the strainer assembly.
Patent CA-3138425-A1 (CA)
Title: Metered dispense pot filler
Inventor: WALES JOSHUA
IPC: E03C1/04
Filed: 2021-11-10
Abstract: A pot filler including a metered dispense input device for dispensing of predetermined volumes of water. The pot filler illustratively includes an electrically operable valve operably coupled to a metered dispense input unit, and a control module configured to control operation of the electrically operable valve.
Patent CA-3139240-A1 (CA)
Title: Zero emission fuel
Inventor: DEL CAMPO OSVALDO
IPC: C10L3/06
Filed: 2021-11-16
Abstract: A zero emission liquefied fuel having a composition including a first portion and a second portion, where the first portion is one of (a) a Liquefied Natural Gas (LNG) or (b) a Compressed Natural Gas (CNG) sourced from fossil decomposition and the second portion is a Renewable Natural Gas (RNG). The Renewable Natural Gas (RNG) can be sourced from any renewable source, but is preferably sourced from dairy. The fuel composition can be formulated having a carbon intensity equal to zero.
Patent CA-3139759-A1 (CA)
Inventor: TANG FANGRU
IPC: G08B13/193
Filed: 2021-11-23
Abstract: The present disclosure relates to an imaging device and a camera having a night vision mode. The imaging device including: a main body having a panel; a lens exposed from the panel and performing imaging according to received light; at least one infrared LED provided around the lens and emitting infrared light if the amount of visible light received by the lens is less than a predetermined value; a control circuit controlling imaging of the lens, wherein the lens is allowed to perform imaging when the control circuit is turned on, and the lens is prohibited from performing imaging when the control circuit is turned off; a switch provided in the control circuit and turning on or turning off the control circuit; and a baffle provided on the main body to cover at least a portion of the panel, the baffle transmitting infrared light emitted from the at least one infrared LED, and moving between a first position and a second position, wherein in the first position, the baffle triggers the switch to turn on the control circuit, and in the second position, the baffle triggers the switch to turn off the control circuit. The imaging device achieves thorough privacy protection and avoids the reduction of the lifespan of the infrared LED.
Patent CA-3140740-A1 (CA)
Inventor: RIBO Romain
IPC: F16D11/14
Filed: 2020-05-20
Abstract: A device for coupling two shafts end to end, comprising a pair of dog clutches (16, 28). Each dog clutch is configured so as to be able to be secured to an end of a shaft to be coupled, and the two dog clutches (16, 28) have complementary shapes. A first dog clutch (16) is pivotably mounted in a first casing (6). A second dog clutch (28) is pivotably mounted in an intermediate bearing (8). The intermediate bearing (8) is slidably mounted in a second casing (10) assumed to be fixed, the intermediate bearing (8) being able to slide with respect to the second casing (10) in a direction, termed longitudinal direction, parallel to the two shafts to be coupled. The intermediate bearing (8) is elastically prestressed in the direction of the first casing (6).
Patent CA-3140931-A1 (CA)
Title: Materiau isolant et procede pour sa production
Inventor: CHLANDOVA GABRIELA
IPC: B28B1/00
Filed: 2020-06-26
Abstract: L'invention concerne un matériau isolant, en particulier un matériau isolant résistant au feu comprenant du verre soluble, caractérisé en ce qu'il est constitué d'un composé durcissable qui contient de 2 à 40 % en poids de billes de plastique, de 55 à 95 % en poids d'une solution aqueuse de silicate de sodium, de 2 à 6 % en poids d'hydroxyde d'aluminium, et de 0,1 à 0,5 % en poids d'un stabilisant de verre soluble. L'invention concerne également un procédé de production d'un matériau isolant, en particulier un procédé de production d'un matériau isolant résistant au feu comprenant du verre soluble et des billes en matière plastique, selon la revendication 1, le procédé est caractérisé en ce que les billes en matière plastique sont d'abord mélangées avec une solution aqueuse de noir de carbone de manière à revêtir toute leur surface en noir de carbone, de l'hydroxyde d'aluminium est ajouté et l'ensemble est mélangé de manière à former un mélange isolant, ensuite un stabilisant de verre soluble est ajouté à la solution aqueuse de silicate de sodium, puis un durcisseur de verre soluble est mélangé à cette solution, ladite solution étant encore agitée pendant 1 à 10 minutes pour former une solution de liant, et le mélange isolant est ajouté à la solution de liant avec une agitation constante, puis l'ensemble est mélangé, et le mélange résultant est ensuite versé dans le site d'application.
Patent CA-3141015-A1 (CA)
Inventor: NIEMINEN HENRI
IPC: C08L25/06
Filed: 2020-06-26
Abstract: A method for recycling polystyrene in a dissolution recycling process, in which method 1,3-dioxolane or isoamyl acetate is used as a solvent for dissolving polystyrene.
Patent CA-3146108-A1 (CA)
Inventor: EIDE ANDREW
IPC: A61L2/10
Filed: 2020-08-06
Abstract: Disclosed herein is a photocatalytic oxidation device that includes a frame and a pair of opposing photocatalytic cell panels. An ultraviolet lamp is disposed within an interior chamber and, when activated, causes the generation of oxidizers at the cell panels. Air is passable through apertures of the cell panels and thus may be moved through the device. The device is structurally configured and dimensionally optimized to provide effective photocatalytic activity without overly restricting airflow.
Patent CA-3147640-A1 (CA)
Title: Second generation seneca valley virus oncolytic therapy: compositions and methods thereof
Inventor: RACANIELLO VINCENT R
IPC: C12N15/36
Filed: 2020-07-20
Abstract: Provided herein are compositions and methods of using Seneca Valley Virus (SVV) or a derivative thereof and an interferon type I (IFN-I) inhibiting agent comprising an mTOR inhibitor for treating a cancer in a subject. The disclosed methods particularly rely upon the expression level of an ANTXR1 and the expression level of IFN-I in the cancer from the subject. Also provided herein are methods for predicting the efficacy of an SVV treatment comprising IFN-I inhibiting agent.
Patent CA-3148593-A1 (CA)
Title: Method for improving digestive health
Inventor: CHAE LEE
IPC: A23L33/00
Filed: 2020-07-27
Abstract: Disclosed herein are methods for improving digestive health by providing a consumable composition. Some embodiments provided include, for example, administering a compound of Formula (I) or compound of Formula (II). Some embodiments provide the composition is formulated as a dietary supplement, food ingredient or additive, a medical food, nutraceutical or pharmaceutical composition.
Patent CA-3149505-A1 (CA)
Title: Compositions de cannabis a base de proteines
Inventor: LECHT SHIMON
IPC: A61K36/185
Filed: 2020-08-26
Abstract: La présente invention concerne de nouvelles compositions comprenant un composant de cannabis choisi dans le groupe consistant en : un cannabinoïde, un flavonoïde et un terpénoïde ; et une protéine, choisie dans le groupe consistant en: le lactosérum et une protéine végétale. Selon un mode de réalisation, le composant de cannabis est lié de manière non covalente au lactosérum ou à la protéine végétale. La protéine végétale peut être choisie dans le groupe consistant en : une protéine de soja, une protéine de pois, une protéine de riz, une protéine de chanvre, et une protéine de houblon ou une autre protéine d'origine végétale.
Patent CA-3149605-A1 (CA)
Inventor: XU HANMEI
IPC: A61P11/00
Filed: 2020-10-26
Abstract: L'invention concerne un polypeptide de fusion de recombinaison, son procédé de préparation et son utilisation. L'invention concerne un polypeptide de fusion de recombinaison, ledit polypeptide de fusion de recombinaison étant exprimé en tant que formule générale suivante : X-lieur1-Y, Y-lieur1-X, X-lieur2-Y, Y-lieur2-X, dans laquelle X représente PRCWRGEGGGGIVRRADRAAVPGGGGRGD et Y représente acétyl-SDKPGGGGTSLDASIIWAMMQNGGGGLSKL. L'utilisation du traitement comprend la fibrose pulmonaire, la fibrose hépatique, la fibrose cutanée, la fibrose rénale, la fibrose cardiaque et la lésion des tissus pulmonaires.
Patent CA-3150461-A1 (CA)
Inventor: SZYDLOWSKI NICO
IPC: F41A9/59
Filed: 2020-07-31
Abstract: L'invention concerne un dispositif d'évacuation (1) conçu pour évacuer des éléments de ceinture de différentes munitions, en usage par exemple sur des véhicules. Ce dispositif d'évacuation (1) comprend au moins une surface d'évacuation (2) conçue pour évacuer les éléments de ceinture. Cette surface d'évacuation (2) est ménagée sur une base (7) conçue de manière à être molle et souple. Le dispositif d'évacuation (1) comprend au moins un élément de fixation (6). Ainsi, le dispositif d'évacuation peut être fixé sur le véhicule ou une tour du véhicule.
Patent CA-3152484-A1 (CA)
Title: Procede et systeme pour mettre en oeuvre une recherche vocale en nuage elastique utilisee par des clients de boitier decodeur (stb)
Inventor: WILDE JAMES
IPC: H04N21/422
Filed: 2020-08-18
Abstract: L'invention concerne des systèmes et des procédés pour assurer une recherche vocale dans un environnement en nuage élastique communiquant avec un boîtier décodeur (STB), par réception, par un serveur de recherche vocale en nuage, de paquets audio à modulation par impulsions et codage (PCM) transmis à partir du STB ; envoi des paquets audio PCM à un service de traitement du langage naturel (NLP) pour une conversion en texte ; envoi des ensembles de texte à un serveur de recherche vocale en nuage élastique pour interroger des données de service de guide électronique de programmes (EPG), de canal et de programme associées à l'ensemble de textes, le service EPG renvoyant au moins des données de canal et de programme identifiées ; en réponse à un retour identifié de données de canal et de programme de télévision, envoi d'ensembles de texte à un service de recherche pour effectuer une recherche élastique pour des données associées provenant d'une pluralité de sources de recherche différentes et renvoyer des résultats de recherche et des codes d'erreur à un demandeur.
Patent CA-3154130-A1 (CA)
Inventor: JACOBE HELEN
IPC: A01N63/00
Filed: 2020-09-11
Abstract: The present disclosure relates to hydrogels composition comprising protist cells. In particular, the present disclosure relates to hydrogel compositions which may be used to encapsulate or suspend ciliated protist cells, and methods of preparing the same. The present disclosure further relates to methods of infecting molluscs with a ciliated protist cell, and methods and compositions for stabilising ciliated protist cells.
Patent CA-3155137-A1 (CA)
Inventor: RABUKA DAVID
IPC: C07D209/56
Filed: 2019-10-04
Abstract: La présente invention concerne des structures de conjugué anticorps anti-CD25-maytansine. L'invention concerne également des méthodes de production de ces conjugués, ainsi que des méthodes d'utilisation de ceux-ci.