baber/WOPTO huggingface dataset:
Patent DO-P2002000353-A (DO)
Title: Nuevos compuestos antiinflamatorios de triazolopiridinas
Inventor: DOMBROSKI MARK ANTHONY
IPC: A61P3/10
Filed: 2002-03-06
Abstract: La presente invención se refiere a nuevas Triazolopiridinas de fórmula I en la que Het es un heterociclo de 5 miembros opcionalmente sustituido que contiene uno a dos heteroátomos seleccionados de nitrógeno, azufre y oxígeno, debiendo ser nitrógeno al menos uno de dichos heteroátomos; R2 se selecciona del grupo constituido por hidrógeno, alquilo C1-C6 u otros sustituyentes adecuados; R3 se selecciona del grupo constituido por hidrógeno alquilo C1-C6 u otros sustituyentes adecuados; s es un número entero de cero a cinco; a intermediarios para su preparación, a composiciones farmacéuticas que los contienen y a su uso medicinal. Los compuestos de la presente invención son potentes inhibidores de las MAP quinasas, preferiblemente de la P38 quinasa. Son útiles en el tratamiento de la inflación, osteoartritis, artritis reumatoide, cáncer, reperfusión o isquemia en la apoplejía o en el ataque cardiaco, enfermedades autoinmunes y otros trastornos.
Patent DO-P2012000289-A (DO)
Title: Proceso para preparar compuestos de pirimidinona
Inventor: CARDWELL KEVIN STUART
Filed: 2012-11-15
Abstract: Esta invención se refiere a métodos para preparar un compuesto de fórmula (l) y a intermedios para ello siendo los compuestos de fórmula (l) útiles para tratar enfermedades cardiovasculares e inflamatorias tales como aterosclerosis.
Patent DO-P2014000033-A (DO)
Title: Aminoquinazolinas como inhibidores de quinasa
Inventor: ROMANO JOSEPH J
IPC: A61K31/535
Filed: 2014-02-18
Abstract: Se describen compuestos que tienen la fórmula: en donde: R1, R2, R3, y Z son como se define aquí, y procedimientos para hacer y usar los mismos.
Patent DO-P2020000071-A (DO)
Title: Proteínas trispecificas y métodos de uso
Inventor: HOLGER WESCHE
IPC: A61K39/395
Filed: 2020-05-06
Abstract: En este documento se proporcionan proteínas triespecíficas dirigidas contra agentes de maduración de células B (BCMA) que comprenden un dominio de unión a CD3, un dominio de prolongación de la semivida y un dominio de unión a BCMA. También se proporcionan composiciones farmacéuticas de las mismas, así como ácidos nucleicos, vectores de expresión recombinantes y células hospederas para preparar dichas proteínas triespecíficas dirigidas contra BCMA. También se describen métodos para usar las proteínas triespecíficas dirigidas contra BCMA divulgadas en la prevención y/o tratamiento de enfermedades, afecciones y trastornos.
Patent EE-200000025-A (EE)
Inventor: HELMUT OESTERLE
IPC: E05D7/04
Filed: 1998-05-22
Abstract: The inventive holding device for fixing pins (1) for doors (10) is provided with boreholes (8 and 9) for receiving a fixing pin (1) and an adjusting part (3). Said adjusting part (3) is configured as a threaded bolt and has a collar (5) at its end. Said collar (5) engages in a groove (7) in the free end area of a fixing pin (1) of the hinge (2). The fixing pin (1) is axially displaced when the adjusting part (3) is moved, thus enabling an accurate setting initially and subsequent readjustment.
Patent EE-200300444-A (EE)
Inventor: ANDERSSON GREGER
IPC: H04L12/56
Filed: 2002-03-11
Abstract: The invention relates to a device at a mobile communication system (10) to, at establishing of connection towards a public data communication network (12), identify mobile users (14). The mobile communication system (10) includes at least one first node (16) for handling of packet switching and charging data, at least one second node (18) for establishing of connection to public data communication networks (12) and transmission/mediation of addresses. The communication system (10) in addition includes a third node (22) connected to said first node/nodes (16) and to said second node/nodes (18) for filtering and duplication of modified call detail data records, at which each call detail data record includes a connection between an address and a subscriber. The third node (22) distributed the modified call detail data records to one to the third node (22) connected first memory device (24), at which a mobile user (14) is identified by means of the first memory device (24) and one to said first node/nodes (16) connected second memory device (26) which stores subscriber information.
Patent EE-200400106-A (EE)
Inventor: LOEFQVIST ANDERS
IPC: C12N11/08
Filed: 2003-02-18
Abstract: Method for biological purification of water such as wastewater using a carrier material, wherein the water is treated in a reactor containing carriers for biofilm growth. These carriers are kept in movement in the water and are designed so that they have well-defined passages or compartments providing a surface for biofilm growth, which is protected against collision with the surfaces of other carriers. The carriers have a width or diameter greater than 20 mm, the protected area is larger than 1000 m<2>/m<3> carrier element volume, the length of the passages or the depth of the compartments in the carrier elements as a mean value is smaller than 6 mm or smaller than 3 mm, respectively, and the ratio between the passage lengths or compartment depths and the longest dimension of the inlet openings to the passages or compartments, respectively, is smaller than 3. <IMAGE>
Patent GB-189706885-A (GB)
Title: Improvements in Boots and Shoes.
Inventor: WARNER JOHN FRANKLIN
Filed: 1897-03-16
Granted: 1897-10-23
Abstract: 6885. Warner, J. F. March 16. Ventilating; soles.-An air-passage B, B is formed all round, between the inner and outer soles, communicating with an open-ended tube C at the heel. Between the inner and outer soles, at the fore part of the shoe, is placed a tubular elastic fabric R, the tubes R<1> of which act as pumps to draw in and expel air through the passages B and C. The spaces S' between the tubes R<1> assist in this aircirculation and also cause air-circulation in the interior of the boot or shoe through openings V, V in the inner sole. In the Figures the outer sole is not shown.
Patent GB-189708686-A (GB)
Title: Improvements in Fillings for Coating Wood before Painting the same.
Inventor: PHILLIPS PHILLIP
Filed: 1897-04-05
Granted: 1897-05-15
Abstract: 8686. Phillips, P. April 5. Painting.-A filling for painter's use consists of a mixture of white lead, ground pumicestone, varnish, and powdered asbestos. Pyrites or other materials may be added, or the asbestos may be omitted.
Patent GB-189721020-A (GB)
Title: A Combined Water Heater and Steam Condenser for Boilers and the like.
Inventor: NESBIT DAVID MEIN
Filed: 1897-09-13
Granted: 1898-09-13
Abstract: 21,020. Nesbit, D. M., and Clowes, W. Sept. 13. Feedwater, heating.-Exhaust steam is passed through the tubular apparatus shown in Fig. 1, and condensed by the surrounding cold water, which on becoming heated is used for feeding boilers or for other purposes. The steam enters the compartment D and circulates through the tubes C, round which the cold water is passing. Uncondensed steam escaping from the tubes is met by cold-water jets from the serpentine pipe K. A steam-air ejector M removes air from the chamber B and assists in the condensation of the steam. When the condensed steam falls below the predetermined level x-y in the chamber B, a steam-distribution valve is operated by one of a pair of floats, so as to shut off the steam from the steam pump which is withdrawing the water from the chamber through the outlet N. At the same time another valve is opened by the other float and water, hot or cold, supplied to the spray pipes K. On the rise of water to, say, the level v-w, the reverse action takes place. The strainer M is fitted to the bottom of the chamber B. The arms of the floats may be hollow and open to the atmosphere.
Patent GB-189805705-A (GB)
Title: Improvements in the Manufacture and Production of Electrodes for Secondary Batteries.
Inventor: PIEPER HENRI
Filed: 1898-03-08
Granted: 1899-01-14
Abstract: 5705. Pieper, H. March 8. Secondary batteries.-Hollow cylindrical electrodes are made from a flat lead plate E, Fig. 2, which has ribs or projections a extending from top to bottom and standing at right-angles to the plane of the plate E. The spaces between the ribs a are filled with active material c, and the plate is then bent into cylindrical form with the ribs a on the inner side.
Patent GB-189806100-A (GB)
Title: Improvements in Corsets.
Inventor: JOHNSON JOSEPH
Filed: 1898-03-12
Granted: 1898-12-17
Abstract: 6100. Johnson, J., MacLeod, D., and Wager, G. March 12. Corsets.-The lower part of the corset is divided at each side, and the divided parts are connected together by two elastic pieces B, B<1> one over the other, the said pieces being arranged between and attached near to two steels A, A' which meet at the top of the corset and radiate outwards in V-shape from that part.
Patent GB-189806529-A (GB)
Title: Improvements in Bait-cans and Carriers for the same.
Inventor: SHARD WILLIAM DANIEL
Filed: 1898-03-17
Granted: 1898-05-07
Abstract: 6529. Shard, W. D. March 17. Luggage-carriers. - To enable an angler's bait can to be carried on a bicycle, a bracket d is provided, a loop e on which engages with the stem of the handle-bar. The outer ends c<1> are adapted to engage with holes in the bail of the can.
Patent GB-189807087-A (GB)
Title: Improvements in the Method of and Apparatus for Hop Drying.
Inventor: BLACKIE ALFRED
Filed: 1898-03-23
Granted: 1899-02-11
Abstract: 7087. Blackie, A. March 23. Drying-kilns.-Hops are dried in frames A having bottoms B and lids C of perforated or porous material. These frames rest between the guides g of a circular or rectangular carrier G on the floor of a circular or rectangular kiln, and may each consist of one or more sections. The circular carrier G, Fig. 6, runs on wheels H so that the frames can in turn be inserted from, or withdrawn into, a cooling-room I. One of the wheels H may be made removable, so that the carrier may be rotated on two of its axles to invert the frames. In the rectangular form, the carrier may be made in two horizontally-pivoted pieces. The frames have partitions E made in sections, which may be removed to allow of the lowering of the lid C as the hops contract. Means are provided to lock the lids in position and retain the frames in the carrier. The frames after removal from the carrier are cooled, and the contents are subsequently discharged through a shutter F.
Patent GB-189815244-A (GB)
Title: Improvements in Tobacco Pipes.
Inventor: WILSON MATTHEW
Filed: 1898-07-12
Granted: 1899-05-27
Abstract: 15,244. Wilson, M. July 12. Tobacco pipes.-The stem B of the pipe is provided with a smoke bore or passage D, and below this with a bore E which forms a well or receptacle for nicotine &c., and communicates with a screw plug G. The mouthpiece C has also an upper smoke bore H and a lower bore or well J. A chamber K is left between the bores of the stem and mouthpiece, and on the sides of this may be cut a spiral groove.
Patent GB-189817524-A (GB)
Title: An Improved Colourimeter, more especially applicable for use as an Ozonometer.
Inventor: OTTO MARIUS
Filed: 1898-08-13
Granted: 1898-09-24
Abstract: 17,524. Otto, M. Aug. 13. Colours, testing. -The apparatus is especially applicable as an ozonometer for determining the percentage of ozone in air by means of the tint imparted, but it may be used for other like purposes, such as the testing of liquids. The ozonized air is led through a tube T' t<1> T<1>1, from the pipe E to the pipe s, while pure air is contained in the parallel tube T<2> t<2> T<1>2. Rays of light pass through both tubes from a lamp S, being deflected by the prism P and mirror N, and those that have passed through the pure air are turned through two prisms P', P<2> of tinted glass, Fig. 1<b>, which can be adjusted by a right and left handed screw F, an arrangement practically equivalent to a plain sheet of adjustable thickness. The operator looks through an eye-piece L and turns the screw F till the same tint is seen in both halves of the field, when the percentage required is read off on the scale e by a vernier v. In testing liquids, the prisms are turned out of the way and columns of the liquid to be tested and of a standard liquid are introduced into the two tubes, the height of the former being varied till the tints in the eye-piece are the same. A thermometer and pressure gauge are attached to the apparatus with a view to correction for temperature and pressure.
Patent GB-189822031-A (GB)
Title: Improvements in Machinery for Making Envelopes.
Filed: 1898-10-19
Granted: 1899-09-02
Abstract: 22,031. Abel, C. D., [Gebr³der Tellschow]. Oct. 19. Envelopes-Relates to mechanism for gumming envelope blanks and feeding them to the folding- apparatus. Fig. 1 shows a sectional elevation. The gummer arms are carried by guide-blocks d movable on vertical rods e and pressed downwards by springs f. Each block d is provided with a roller h running upon a circular path i, one part of which i<1>, sufficiently large to take two adjacent rollers h, is separate and may be raised and lowered by means of the rod i<2> operated by an eccentric. The rear gummer arm of the two which descend, takes a blank from the pile, while the forward gummer arm deposits the blank it holds on the folding-apparatus. Each time the part i<1> is raised to the level of the part i, the gummer arms are rotated sufficiently far to bring the arm carrying the blank over the folding-apparatus and a fresh arm over the pile of blanks.
Patent GB-189904442-A (GB)
Title: Improvements in the Manufacture of Accumulator Plates.
Inventor: MAJERT WILHELM
Filed: 1899-03-01
Granted: 1899-05-06
Abstract: 4442. Majert, W., and Berg, F. March 1. Secondary batteries.-Relates to plates or electrodes which have grooves and ribs formed on them by cutting-tools such as are described in Specification No. 996, A.D. 1897, and consists in imparting an oscillatory movement to the tools during the cutting operation, so that arc-shaped grooves and ribs are formed on the plate. Fig. 4 shows a plate P to be acted upon by the tools, the plate being divided into panels p<2> by intervening ribs, and Fig. 3 shows in plan the plate P being acted upon by cutting-tools f, which are simultaneously moved and oscillated by a connecting rod h<1>. The plate P is fixed on a sliding bed-plate b, and is fed forward between the strokes of the tools by ratchet and pawl mechanism c. In order to hold the plate down and to polish it, a roller is adjustably mounted in the tool-holder and presses on the plate in close proximity to the cutting-tool.
Patent GB-189905929-A (GB)
Title: An Improved Water Meter.
Inventor: REISERT HANS
Filed: 1899-03-18
Granted: 1899-12-09
Abstract: 5929. Reisert, H. March 18. Weight water-wheel meters.-A cylinder is supplied from a central hollow shaft g', the water flowing in turn into the compartments 1, 2, 3, 4, Fig. 1, as they are brought round under the excess of weight on one side. Pockets s', s<2>, s<3>, s<4> receive the first flow, and, as the water discharges through the ports r<1>, r<2>, r<3>, r<4>, excess of water runs over from each compartment into the next. The arrangement may be somewhat modified. Thus, in Fig. 9, the pockets are dispensed with, and the partitions curve spirally to the discharge port.
Patent GB-189907413-A (GB)
Title: Improvements in or connected with Tyres for the Wheels of Cycles or other suitable Road Vehicles.
Inventor: HARRAWAY EDWIN LOUIS
Filed: 1899-04-08
Granted: 1900-02-10
Abstract: 7413. Harraway, E. L. April 8. Tyres, elastic other than pneumatic; felloes or rims; spokes.-Relates to a spring tyre, two forms of which are shown in section in Figs. 3 and 5. Secured to the rim B in any manner is a rubber or similar cover A, within which a separate lining C of leather, metal, or the like is placed. Helical springs D are placed radially at short distances apart, so as to bear at one end against the rim and at the other against the lining. The springs may be provided with shaped plates F, which may be secured either to the rim or, as shown in Fig. 3, to the lining. In the form shown in Fig. 5, the springs are connected to the spoke nipples E, and the spokes H are produced into the springs. In a modification, pins, secured to the lining, pass into the springs and through holes in the rim.
Patent GB-189912370-A (GB)
Title: Improvements in and relating to Incubators.
Inventor: CALVERT THOMAS HORSFALL
Filed: 1899-06-14
Granted: 1900-04-14
Abstract: 12,370. Calvert, T. H. June 14. Incubators.-Relates to the construction of the egg drawer, and to means for turning the eggs without opening the drawer. The drawer 1 is circular, and is provided with a movable dished bottom 2 of perforated metal or other material. The bottom 2 is grooved concentrically at 2<a>, to form channels for the eggs. The bottom 2 is provided with a rack engaging a pinion 5 on a shaft 6 which extends outside the incubator. A fixed wire frame 8 is provided to prevent the eggs from moving round with the bottom 2 without being turned. The wire frame may be dispensed with, and the bottom 2 arranged on an incline so that the eggs will roll round when the bottom 2 is rotated.
Patent GB-189915094-A (GB)
Title: Improvements in the Locking and Unlocking of Drawing Compasses.
Inventor: TUCKER GEORGE
Filed: 1899-07-22
Granted: 1900-06-23
Abstract: 15,094. Tucker, G., and Daws, G. July 22. Compasses, drawing.-Relates to the means for locking the pivot of the legs in the adjusted position. A metal blank is cut to the shape shown in Fig. 6, and the parts a', a<2> bent to form a barrel for receiving the pencil B, while the ears a<3>, a' are bent backwards, parallel to each other, and receive the end of the leg C. The shank d' of the turn button D is passed through holes in the parts a<3>, a<4>, the end of the leg, and a washer, and is then riveted over. A wedge or incline a<5>, a<7> is formed in the ear a<4> so that, when the button D is turned about parallel to the pencil B, the legs are locked in position. The barrel and ears may be made in two separate parts riveted together.
Patent GB-189922187-A (GB)
Title: Improvements in Lighters for Cigars, Cigarettes and the like.
Inventor: BUTCHER LEOPOLD ERNEST
Filed: 1899-11-06
Granted: 1900-09-29
Abstract: 22,187. Butcher, L. E., and Wood, M. G. Nov. 6. Lighters, pipe, cigar, and like.- The lighter is constructed with a case similar to a watch case, the cover b being lined with tinder l. A ring handle exterior to the case operates a shaft g, which by means of gearing f communicates motion to an emery wheel e, against which is pressed a steel plate i. A shower of sparks is directed on to the tinder through an opening m, which can be closed by a cover n.
Patent GB-189922341-A (GB)
Title: Improvements in Process and Apparatus for Producing Stock Material from Metal Ingots or Billets.
Inventor: MORSE CHARLES SEYDAM
Filed: 1899-11-08
Granted: 1900-02-10
Abstract: 22,341. Morse, C. S. Nov. 8. Shearing; bending; wire; rods and bars; plates.-Relates to a method of producing " stock material such as plates, strips, wire, &c., from billets or ingots, and to a shearing-machine for use therein. An ingot is first made into a hollow billet and then into a tube by a suitable rolling process. The tube is then cut longitudinally to form one plate or a number of strips, or is cut spirally to form a continuous wire strip which may be subsequently drawn into wire. The shearing- machine has disc blades b, b<1>, driven in the same direction and at the same speed, the lower one supporting the front end of the tube A, the rear end of which is held in a carrier C. The carrier slides on the rods c of a frame C<1>, which can be swivelled and locked by a screw c<7> to alter the pitch of the helix. The carrier and tube are constantly pushed forwards by a weighted cord. The carrier is held by a catch c<10> for the insertion of a new tube. The width of the wire strip is determined by an adjustable roller or stop c<12> in front of the lower blade. After leaving the blades, the wire strip passes under a roller c<13>, through a tube d, between adjustable guiderollers d<1>, d', d' to a winding-drum D. The drum has a spiral vane d' to coil the strip, and has a flange e held in place by radially-movable arms e<1>. When a coil is finished, the arms are drawn in by linkwork operated by a button e' as shown in Fig. 7, allowing the flange to be removed and the coil slid off.
Patent GB-189922568-A (GB)
Title: Improvements in Equilibrium Slide Valves for Engines.
Inventor: SCHMOLKA WILHELM
Filed: 1899-11-11
Granted: 1900-09-22
Abstract: 22,568. Schmolka, W. Nov. 11. Slide valves, balancing.-The object is to balance plane slide valves in large engines, especially marine engines. The live steam is admitted to the interior of the valve a, and the exhaust surrounds it, with the result that there is an upward balance of pressure. This is counteracted by pistons h passing through stuffing-boxes i separating the valve-chest from closed cylinders mounted on the valve-chest cover. Water, air, steam, or the like under pressure is admitted to the cylinders by pipes t.
Patent GB-189923725-A (GB)
Title: Improvements in or relating to Space Lines for Type Setting.
Inventor: BAINE JOHN GEORGE
Filed: 1899-11-28
Granted: 1900-01-20
Abstract: 23,725. Baine, J. G. Nov. 28. Late news, means for printing ; type, setting.- Relates to means more particularly for setting up type or linotypes for printing late news and the like, and consists of a spacing strip or rule for placing between the lines. Fig. 1 shows a face view, Fig. 1<a> a plan, and Fig. 1<b> an end view. The spacing-strip A, which may taper from top to bottom and is preferably of less depth than a type body, has fixed at its ends on one side flanges or pieces B, B<1> of the same height and thickness as the type or linotype bodies used. A projection B<3> on the piece B may be provided for printing a number or character, or a space in the piece B may be left for a type used for printing such number or character. The pieces B, B<1> may be perforated for wires or rods which may be passed through perforated types. The spacing-strips and the linotypes or types between them in the spaces C may be secured as described in Specification No. 3649, A.D. 1899.
Patent GB-190002216-A (GB)
Title: Improved Detachable Chair.
Inventor: TREFETZ OSCAR
Filed: 1900-02-03
Granted: 1900-03-03
Abstract: 2216. Trefftz, O. Feb. 3. Chairs.-Relates to a chair in which the parts can be readily detached for renewal or transport. Each leg g, i has a conical part h, k, which fits a corresponding hole in the frame. The front legs also have flxing-screws j, and the back legs have threaded holes into which engage screws e on the back uprights a. The surface c of the back is held by cross-bars b, the upper one of which is secured by bolts d passing through eyes therein and into the sides a. The conical plugs cause the joint to tighten when the new wood contracts.
Patent GB-190003475-A (GB)
Title: An Improved Domestic or Open Fire Stove.
Inventor: CROSTHWAITE JOHN ROBINSON
Filed: 1900-02-22
Granted: 1901-01-19
Abstract: 3475. Crosthwaite, J. R. Feb. 22. Canopies and hoods.- The canopy a, which may be fixed or pivoted as shown, is provided with a central recess c around which the gases have to pass (when the canopy is in the position shown in thick lines) to reach the outlet f to the chimney, whereby some of the heat of such gases is abstracted by the obstructing recess. To further increase the travel of the gases, vertical wing plates e may be attached to the top edges of the recess.
Patent GB-190004683-A (GB)
Title: Improvements in Brushes.
Inventor: ROTH LEONHARD
Filed: 1900-03-12
Granted: 1900-04-14
Abstract: 4683. Roth, L., and Israelski, M. March 12. Bristles, fixing; stocks; handles.-The tufts of bristles d are attached to the margins of two frames a, b and to cross-bars e hinged or detachably and interchangeably connected to one of the frames b to facilitate cleaning. The frames a, b, which together form the stock, slide into one another, and are preferably hinged at k where they join the handles h.