baber/WOPTO huggingface dataset:
Patent JP-2011502947-A (JP)
Title: ガラスシートに焼結フリットパターンを生成するためのフリット含有ペースト
IPC: H01L51/50
Filed: 2008-11-10
Abstract: ＯＬＥＤ（１８）ディスプレイ装置（１０）のカバーとして使用するガラスシートなど、ガラスシート（１２）上への焼結フリットパターン（１４）の生成に使用するためのペーストを提供する。ペーストには、ガラス粒子、充填剤粒子、および媒体が含まれる。充填剤および／またはガラスの粒子の大きさは、従来技術のペーストと比較して縮小されている。ペーストを使用して生み出される焼結フリットの孔隙率および表面粗さの低下、ならびに、ＯＬＥＤパッケージの生産に利用可能な処理窓、および、それらのパッケージの気密性および強度の改善が報告される。
Patent JP-2011504405-A (JP)
Title: 可変コイル導体ピッチを有する移植可能リード線
IPC: A61N1/36
Filed: 2008-12-04
Abstract: 磁気共振画像法（ＭＲＩ）などの医療手順中に移植可能リード線を磁界から保護するためのシステムおよび方法が説明される。様々な実施形態において、リード線は、らせん形の形状であり、１つ以上の外部シールド導体によって少なくとも部分的に放射状に囲まれた内部導体を含む。内部導体のピッチ、および一部の場合において外部導体のピッチも、リード線の長さに沿って（例えば、連続的にまたは特定の点で）変動され得、リード線の長さに沿って複数の高インピーダンス点を形成し得、このことは、磁気共振画像デバイスのインタロゲーション周波数（例えば、６４ＭＨｚ、１２８ＭＨｚ、または類似のもの）で電磁エネルギの消散という結果になる。一部の実施形態において、内部導体のピッチにおける可変性は、シヌソイド関数、変形方形波関数、または他の反復パターンに従う。
Patent JP-2011506007-A (JP)
Title: ガス透過性膜を有するデュアルチャンバー注射デバイス
IPC: A61M5/28
Filed: 2008-12-05
Abstract: 本発明は、一つ又はそれ以上の液密で、ガス透過性の膜（８）及び場合によりバルブ膜（１５）が、シリンダーエレメント（２）の壁中に、又はクロージャエレメント（６）中に配列され、ピストン（３）、（３ａ）及び（４）が遠位方向に動くときに、それを通して、チャンバー中に存在するガスがシリンダーエレメント（２）中から逃げることできることを特徴とする、シリンダーエレメント（２）、二つのピストン（３）及び（４）、及び場合により中間ピストン（３ａ）を含むデュアル−チャンバー注射デバイスに関する。 【選択図】図１
Patent JP-2011506995-A (JP)
Title: 精神障害を診断及び監視するための方法及びバイオマーカー
IPC: G01R33/465
Filed: 2008-12-18
Abstract: 対象から採取された試料における、1つ以上のペプチドバイオマーカーのレベルを測定することを含む、精神障害又はその素因を診断又は監視する方法。 【選択図】なし
Patent JP-2011507583-A (JP)
Title: オブジェクトの特性を測定するための装置、方法及びコンピュータプログラム
IPC: A61B5/0408
Filed: 2008-12-16
Abstract: 本発明は、オブジェクトの特性を測定する装置に関する。本発明は、対応する方法及びコンピュータプログラムに関する。本装置は、オブジェクトの特定を測定するため、オブジェクトとの間で電磁波を送受信するためのアンテナを有する。アンテナは、オブジェクトのさらなる特性を測定するための電極として機能する導電性要素を有する。
Patent JP-2011508632-A (JP)
Title: 骨盤機能障害を治療する器具および方法
IPC: A61F2/04
Filed: 2008-12-23
Abstract: 一実施形態では、装置は、使い捨て骨盤領域内支持部分と、支持部分から延在するストラップとを含む。ストラップは、ある長さを有し、骨盤組織内に少なくとも部分的に配置されるように構成される。スリーブは、ストラップの少なくとも一部上に解放可能に配置される。スリーブは、ストラップの長さよりも大きな長さを有する。いくつかの実施形態では、スリーブの長さは、ストラップの長さの少なくとも２倍である。いくつかの実施形態では、縫合糸によって、スリーブをストラップに連結する。また、装置は、スリーブの内部に少なくとも部分的に配置され、スリーブの内部に２本の糸を形成する縫合糸を含み得る。２本の糸は、スリーブの分離器部分によって画定される距離だけ隔てられる。
Patent JP-2011517929-A (JP)
Title: 発現ベクター
IPC: A61K35/76
Filed: 2009-04-16
Abstract: 従来の発現ベクターは、大腸菌由来のプラスミドと形質転換菌由来のプラスミドとを融合した、大腸菌と形質転換菌との双方で機能するシャトルベクターであり、大腸菌以外の形質転換菌のみで機能する発現ベクターは知られていなかった。本発明は、大腸菌以外の形質転換菌のみで複製され、当該形質転換菌以外の菌では複製されない発現ベクター、該発現ベクターで形質転換された嫌気性微生物からなる遺伝子輸送担体等を提供することにある。   本発明の発現ベクターは、嫌気性菌で機能するプラスミドベクターであって、大腸菌で機能するプラスミド複製ユニットを含まない発現ベクターである。より具体的には、（１）大腸菌以外の嫌気性微生物で機能するプラスミド複製ユニットと、（２）目的とする活性を有する蛋白質をコードするＤＮＡならびに嫌気性微生物で機能するプロモーターおよびターミネーターを含むＤＮＡ断片からなる蛋白質発現ユニットを含む発現ベクターである。これにより、形質転換遺伝子が、形質転換菌以外の病原性または好気性菌等で複製されるおそれがない、極めて安全なベクターおよび遺伝子輸送担体を実現することができる。
Patent JP-2011515017-A (JP)
Title: ２層式薄膜ホログラフィック太陽光コレクタ及び太陽光コンセントレータ
IPC: F24S23/75
Filed: 2009-02-09
Abstract: 本願明細書において、記載される様々な実施形態において、光学的に光電池（１１０１）に結合される光コレクタ（１１０２）を備える装置が、記載される。その装置は、体積回折特徴物、表面回折特徴物、体積ホログラム、又は表面ホログラムを備える光転向フィルム又は光転向層を、更に備える。光コレクタ（１１０２）上に入射する光は、反射型又は透過型の体積回折特徴物、表面回折特徴物又はホログラムによって、向きが変えられ、複数の全反射によって、光コレクタによって、（１１０２）を導波される。導波される光は、光電池（１１０１）へ向け替えられる。様々な実施形態において、光コレクタ（１１０２）は、薄く（例えば、１ミリメートル未満）、例えば、薄膜を備える。光コレクタ（１１０２）は、可撓性材料で形成されることができる。
Patent JP-2011514844-A (JP)
Title: 空気式静電噴霧器用密閉型電源
IPC: B05B5/025
Filed: 2009-03-02
Abstract: 塗料吐出装置（２０）が、該塗料吐出装置を作動させて塗料を供給するためのトリガー集成体（２６）と、塗料を放出するノズル（３０）とを含む。塗料吐出装置は、更に、該塗料吐出装置に圧縮気体を供給するための第１のポート（３４）と、該塗料吐出装置に塗料を供給するための第２のポート（３６）とを含む。塗料吐出装置は、更に、シャフト（４２）を有した発電機（３８）を含む。シャフトにはタービンホイール（４０）が取付けられている。第１のポートに供給された圧縮気体を該タービンホイールに衝突させてシャフトを回転させることによって電圧が生成される。電極（６２）が、ノズルに隣接させて設けられており、該電極は発電機に結合され同発電機から受電して塗料を帯電させる。発電機の端部から突出しているシャフトの部分が第１と第２のシール部材によってシールされる。
Patent JP-2011136998-A (JP)
Title: Liquid crystalline compound
Inventor: KIRSCH PEER
IPC: G02F1/13
Filed: 2011-01-06
Abstract: <P>PROBLEM TO BE SOLVED: To provide a liquid crystalline compound that serves as a medium for a MLC, IPS, TN or STN display, has high resistivity value, low threshold voltage, high clearing point and low rotational viscosity.  <P>SOLUTION: The liquid crystalline compound is represented by formula (I). A liquid crystalline medium containing at least the compound of formula (I) and an electro-optical display containing one such liquid crystalline medium are also provided.  <P>COPYRIGHT: (C)2011,JPO&INPIT
Patent JP-2012146496-A (JP)
Title: Led lighting fixture
Inventor: SAITO YUKO
IPC: F21V19/00
Filed: 2011-01-12
Abstract: PROBLEM TO BE SOLVED: To provide an LED lighting fixture, in which holding force for holding a light source unit and a heat radiating plate to a frame body is increased.SOLUTION: The LED lighting fixture 1 is provided with a fixture body 10 and a lighting unit 20 installed on the fixture body 10 using a kick spring 60. The lighting unit 20 is provided with a frame body 21, a light source unit 30 supported by the frame body 21, and a heat radiating plate 37. A spring retainer 24 to which a coil part 61 of the kick spring 60 is connected through a connecting fitting 65 is installed on the frame body 21. The light source unit 30 has an LED 31 arranged on the front side, is mounted on the frame body 21 with its front side facing outside, and has the heat radiating plate 37 installed on the rear side. A locking piece 27 is installed in the spring retainer 24 holding the kick spring 60, and is hooked to a locked piece 37a of the heat radiating plate 37 in the state the spring retainer 24 is installed on the frame body 21 mounted with the light source unit 30 and the heat radiating plate 37.
Patent JP-2012146511-A (JP)
Title: Short-arc type discharge lamp
Inventor: SO YUTAKA
IPC: H01J9/02
Filed: 2011-01-12
Abstract: PROBLEM TO BE SOLVED: To provide a short-arc type discharge lamp having a cathode and an anode arranged as opposing each other in an arc tube, which has a structure of electrodes that prevents blackening of a lamp due to evaporation of an electrode material, with the center of the tip of the anode not projecting beyond a surrounding circular portion, in particular, during normal lighting at rated electric power and full-standby lighting in which standby lighting at low electric power is repeated.SOLUTION: In an opening formed at the tip central part of a tip surface of an anode, an insertion body other than the anode is inserted with a metal-made shock absorbing material having a smaller yield stress than the anode material interposed. The tip of the shock absorbing material is retracted with respected to the tip surface of the anode. In addition, a recess groove is formed across a portion of the anode and a portion of the insertion body that are adjacent to the tip of the shock absorbing material.
Patent JP-2012146132-A (JP)
Title: Method for integrating three-dimensional data and two-dimensional data with each other, and watching system and monitoring system using the same
Inventor: HAMA HIROMITSU
IPC: G01B11/00
Filed: 2011-01-12
Abstract: PROBLEM TO BE SOLVED: To provide a method for integrating three-dimensional data and two-dimensional image data with each other which can obtain a flexible recognition result with high reliability by associating the three-dimensional data such as distance image data with the two-dimensional image data and complementarily using the distance image data and the two-dimensional image data, and to provide robust monitoring and watching systems using the same.SOLUTION: The system includes: a two-dimensionally data acquiring step of acquiring two-dimensionally data; a three-dimensionally data acquiring step of acquiring three-dimensionally data; an associating step of associating the position of the two-dimensionally data and the position of the three-dimensionally data with each other; and a superimposing step of superimposing the three-dimensionally data on the two-dimensionally data based on a result which has been obtained by associating the positions in the associating step.
Patent JP-2012145514-A (JP)
Title: Measuring apparatus and measuring method
Inventor: UENO TOSHIYA
IPC: G01R19/00
Filed: 2011-01-14
Abstract: PROBLEM TO BE SOLVED: To make a measuring apparatus continuously execute measurement processing of a physical amount using sampling data.SOLUTION: A measuring apparatus includes: a storage part which stores sampling data of an AC signal; a storage processing part which stores, in the storage part, sampling data for a unit processing section U in which one period of the AC signal continues for a plurality of times; and a measurement processing part which measures a physical amount of the AC signal by using the sampling data for the unit processing section U. The storage part is constituted by including two first storage areas F1a, F1b, and the storage processing part executes duplication storage processing for storing the sampling data for the unit processing section U in which an input point of a synchronization signal S3 for instructing synchronization processing to be performed for every regulated section Tr is included in the first storage area F1a with other pieces of sampling data in the regulated section Tr in which the unit processing section U is included, and storing sampling data for a new unit processing section U by using one period in which the input point is included as the first one period in the first storage area F1b.
Patent JP-2012144206-A (JP)
Title: Device for fixing and separating space equipment
Inventor: AMAKATA RAITA
IPC: B64G1/64
Filed: 2011-01-14
Abstract: PROBLEM TO BE SOLVED: To separate space equipment at a desired timing without requiring heating.SOLUTION: A device A for fixing and separating an artificial satellite includes: a mounting base 1 on which an artificial satellite St is mounted; a plurality of fasteners 2 for being engaged with the artificial satellite St to fasten the artificial satellite St onto the mounting base; a plurality of fastener supports 3 provided to respective fasteners 2 to support the fasteners 2 turnably to the mounting base 1 and also imparting an urging force in a direction of releasing the engagement between the fasteners and the artificial satellite St, to the fasteners 2; a plurality of gas cylinders 4 each having a rod 4a connected to each fastener 2 and when being filled with operating gas, moving the rod 4a so as to engage the fasteners 2 with the artificial satellite St; gas piping 6, of which one end is connected to the gas cylinder 4 while the other end of which is opened, and through which the operating gas passes; a shutoff valve 7 provided in the gas piping 6; and a separating spring 5 for imparting an urging force in a direction of separating the artificial satellite St from the mounting base 1.
Patent JP-2012151569-A (JP)
Title: Image reader
Inventor: WASHIDA SATORU
IPC: H04N1/04
Filed: 2011-01-17
Abstract: PROBLEM TO BE SOLVED: To provide an image reader capable of improving accuracy in reading an original by evading an impact which is subjected by a contact image sensor to move between a platen glass and a contact glass by abutment on the reception frame of a guide body, and also reducing the cost of the image reader by simplifying a structure for evading the impact.SOLUTION: A contact glass 19 is supported by a reception frame 25 of a guide body 21 in a state where the lower surface of the contact glass 19 and a lower surface 54 of a platen glass 10 have coplanarity. A height from the bottom surface of an original placement base 12 to the lower surface 54 of the platen glass 10 is defined as H1, and a height to the lower surface 55 of the guide body 21 is defined as H2. The guide body 21 is constituted to satisfy a formula (H2>=H1). A joint seat 51 positioned upper than the lower surface 54 of the platen glass 10 is arranged on the lower surface of the contact glass 19, thereby to receive the joint seat 51 by a reception seat 53 of the reception frame 25 from the side of the lower surface. Thus, the lower surface 55 of the guide body 21 is prevented from projecting to the mobile area of a contact image sensor 36.
Patent JP-2011101045-A (JP)
Title: Wiring board
Inventor: YOKOTA YASUSHI
IPC: H01L23/12
Filed: 2011-01-21
Abstract: <P>PROBLEM TO BE SOLVED: To improve connectivity with an electronic component to be mounted.  <P>SOLUTION: A wiring board includes a wiring member having wiring layers 18a to 18c and insulating layers 20, 20a and 20b laminated, a connection pad 18 disposed in the insulating layer 20 forming a surface of the wiring member, connected to the wiring layers 18a to 18c, and protruding from the surface, and a lead pin 45 having a head portion 45a and a pin portion 45b extending from the head portion 45a. The connection pad 18 comprises a pad body and a surface plating layer, the pad body includes a buried portion buried in the insulating layer 20 and an exposed portion exposed from the insulating layer 20, and the entire exposed portion of the pad body 18 is formed into a curved surface portion, which is coated with the surface plating layer, to which the head portion 45a of the lead pin 45 is soldered.  <P>COPYRIGHT: (C)2011,JPO&INPIT
Patent JP-2012149746-A (JP)
Title: Rotation transmitting device
Inventor: AKIYOSHI KOJI
IPC: F16D27/112
Filed: 2011-01-21
Abstract: PROBLEM TO BE SOLVED: To reduce the weight of a rotation transmitting device by reducing the axial length of an outer ring.SOLUTION: A pair of rollers 15 and an elastic member 21 for energizing the pair of rollers 15 in the direction in which the pair of rollers separate from each other are built in between a cylindrical surface 12 formed at the inner periphery of an outer ring 11 and a cam surface 14 formed at the outer periphery of an inner ring 13. A retainer 16 for retaining the pair of rollers 15 and the elastic member 21 is formed by a control retainer 16A and a rotation retainer 16B, the control retainer 16A and the rotation retainer 16B form a combination in which pillar parts 25, 29 formed at the outer peripheral parts of flanges 24, 28 are alternately arranged in a circumferential direction, a pocket 31 is formed between the adjacent pillar parts 25, 29, and the pair of rollers 15 built in the pocket 31 are displaced to an engagement release position by being pressed by the pillar parts 25, 29 by the relative rotations of the control retainer 16A and the rotation retainer 16B.
Patent JP-2011102194-A (JP)
Title: Crane
Inventor: MATSUMOTO TOSHINOBU
IPC: B66C5/02
Filed: 2011-01-24
Abstract: <P>PROBLEM TO BE SOLVED: To cover a weakness of a vertical direction (a tension direction) of a seismic isolation device without destroying characteristics in a horizontal direction of a laminated rubber type seismic isolation device.  <P>SOLUTION: The crane includes a crane structure 3 mounted on a travelling device 2. The travelling device 2 or the crane structure 3 is provided with: the laminated rubber type seismic isolation device 4; an uplift prevention means 5 for preventing uplift of the crane structure; a restriction means 6 for restricting horizontal movement of the crane structure during operation; and a restriction releasing means 18 for releasing restriction of the crane structure when an earthquake occurs.  <P>COPYRIGHT: (C)2011,JPO&INPIT
Patent JP-2012154774-A (JP)
Title: Gas sensor
Inventor: UEDA SEIJI
IPC: G01N27/409
Filed: 2011-01-26
Abstract: PROBLEM TO BE SOLVED: To provide a gas sensor capable of preventing heat degradation of a rubber cap attached to the rear end side of a main metal fitting.SOLUTION: The gas sensor includes: a gas sensor element 10; a main metal fitting 138 for holding the gas sensor element 10, a metallic outer cylinder 144 attached to the outer periphery of the main metal fitting 138 and extended to a rear end from the main metal fitting 138; a lead wire 146 electrically connected to the gas sensor element 10 on the inside of the outer cylinder 144 and drawn out to the rear end from the outer cylinder 144; and a rubber cap 150 interpolated into the rear end side of the outer cylinder 144 and forming a through hole 161 for inserting the lead wire 146 in an axial direction, and further includes a metallic heat radiation member 50 attached to the outer periphery of the outer cylinder 144. The heat radiation member 50 includes a connection part 51 connected to an area S further rear end side from the rear end of a contact part Wbetween the main metal fitting 138 and the outer cylinder 144 out of the outer periphery of the outer cylinder 144 and further tip side from the tip of the rubber cap 150, and a heat radiation main part 53 separated from the outer periphery of the outer cylinder 144 while being connected to the connection part 51 and arranged so that its own rear end is located on the tip side from the rear end of the rubber cap 150.
Patent JP-2011183377-A (JP)
Title: Denaturation treatment method for substance
Inventor: NIINO KIYONORI
IPC: B01J19/08
Filed: 2011-01-31
Abstract: <P>PROBLEM TO BE SOLVED: To enable denaturation treatment of an economically more advanced substance with small consumption of magnetic energy by improving efficiency of the denaturation (modification) treatment of a substance using magnetism.  <P>SOLUTION: A substance to be treated is disposed on one side of the layer of copper, or a copper alloy or metal silicon and also a magnetic line of force or a low frequency magnetic wave is incident from another side of the layer of the copper, or the copper alloy or the metal silicon to irradiate the substance to be treated with the magnetic line of force or the low frequency magnetic wave transmitting the layer of the copper, or the copper alloy or the metal silicon, thereby denaturalizing the physical properties of the substance to be treated.  <P>COPYRIGHT: (C)2011,JPO&INPIT
Patent JP-2011178162-A (JP)
Title: Production method of mold for lens molding, production method of lens, lens, production method of precursor for lens molding, and precursor for lens molding
Inventor: MUROFUSE ISAMU
IPC: B29C39/10
Filed: 2011-02-01
Abstract: <P>PROBLEM TO BE SOLVED: To provide a production method of a mold for lens molding, which obtains the mold for lens molding having an accurate shape.  <P>SOLUTION: A photosensitive material 11 of liquid is supplied into a concave part 15 of an original mold 13 to cover the surface of the concave part 15, the photosensitive material 11 is cured, a photosensitive material 23 of liquid is supplied into a concave part 17 of a cured photosensitive material 21 to be covered with a substrate 7, the photosensitive material 23 supplied to the concave part 17 is cured, and a mold 1 for lens molding is produced from the substrate 7 and the cured photosensitive material 21, 27 as the precursor.  <P>COPYRIGHT: (C)2011,JPO&INPIT
Patent JP-2012159757-A (JP)
Title: Color filter, liquid crystal display device, and manufacturing method for color filter
Inventor: NAKAZAWA SHINSUKE
IPC: G02F1/1339
Filed: 2011-02-02
Abstract: PROBLEM TO BE SOLVED: To provide a color filter and the like with less deterioration in display quality, with high productivity and with an adequate cell gap.SOLUTION: A color filter includes a substrate and first to third coloring layers formed in this order on the substrate. In the color filter, a frame part is formed adjacent to a display region. A black matrix, a pixel portion, and the frame part are formed using the first to third coloring layers. A main column is formed by stacking the first to third coloring layers in the display region. A sub-column lower than the main column is formed by stacking two or more of the coloring layers among the first to third coloring layers in the display region. A frame column lower than the sub-column is formed by stacking two or more of the coloring layers among the first to third coloring layers in the frame part.
Patent JP-2012163241-A (JP)
Title: Heat pump water heater with display function of energy reduction amount or the like
Inventor: FUJIMOTO TATSUO
IPC: F24D3/18
Filed: 2011-02-04
Abstract: PROBLEM TO BE SOLVED: To provide a heat pump water heater which has a function of displaying actual achievement of an energy reduction amount and/or COemission/reduction amounts on a monitor.SOLUTION: The heat pump water heater includes: a boiling circulation pipe line 4 in which low-temperature water in a bottom part of a hot water tank 2, in which supply water is supplied in the bottom part, is sucked up by a boiling circulation pump 5, is heated by a heat pump device 1, and is returned to a top part of the hot water tank; mixing valves 10, 12 which mix supply water in hot water discharged from the top part of the hot water tank 2 to adjust at a predetermined temperature; and an electrical device for driving the heat pump water heater. The heat pump water heater obtains a hot water supply heat amount Qo by integrating a heat amount supplied to a hot water supply load over a set time by taking in a measurement value T1 of a water supply temperature, measurement values (T2-T5) of the hot water supply temperatures, and measurement values (F1-F3) of hot water supply amounts, while obtaining an electric power consumption heat amount Qi on calorie basis is obtained by taking in a measurement value W of an electric power consumption amount of the electrical device and integrating over the set time, and obtaining the energy reduction amount Qr=Qo-Qi, which is displayed on the monitor 45.
Patent JP-2011135600-A (JP)
Title: Volume correction apparatus, volume correction method and volume correction program
Inventor: NOGUCHI MASAYOSHI
IPC: H04R3/00
Filed: 2011-02-07
Abstract: <P>PROBLEM TO BE SOLVED: To reduce discomfort by obscuring fluctuation of an output audio volume level at a point of level change, even if a level of an input audio signal is considerably varied.  <P>SOLUTION: A volume correction apparatus includes: a first component gain control section which gain-controls and outputs a first component subject signal with a part of a plurality of audio components of an input audio signal including the plurality of audio components as a main component; a first component gain control signal generation section for generating a first component gain control signal so as to fix an output level of the first component subject signal in the first component gain control section; and another component gain control section which gain-controls and outputs any audio component other than the first component of the input audio signal on the basis of the first component gain control signal.  <P>COPYRIGHT: (C)2011,JPO&INPIT
Patent JP-2012168848-A (JP)
Title: Production line management system
Inventor: SHINAGAWA TOSHIHITO
IPC: H01L21/02
Filed: 2011-02-16
Abstract: PROBLEM TO BE SOLVED: To provide a production line management system which monitors an operation state of a production line, and when occurrence of trouble is detected, clarifies influence of the trouble on progress of the entire production line to notify related parties of the influence of the trouble.SOLUTION: A production line management system has: a plurality of process units composing a production line; means for monitoring an operation state of each process unit; and means for, when trouble occurs in any of the process unit, notifying related parties of the trouble. The production line management system determines influence of the trouble on process units other than the process unit having the trouble by acquiring information concerning a production schedule, and notifies related parties of the influence of the trouble.
Patent JP-2012171883-A (JP)
Title: Nanoparticle containing prostaglandin i2 derivative
Inventor: MIZUSHIMA TORU
IPC: A61P9/12
Filed: 2011-02-18
Abstract: PROBLEM TO BE SOLVED: To provide nanoparticles containing beraprost sodium among prostaglandin I(prostacyclin) derivatives which are therapeutic agents of pulmonary hypertension.SOLUTION: The nanoparticle containing beraprost sodium, which is obtained by hydrophobizing beraprost sodium by metal ion, and by allowing the hydrophobized product to act on poly L-lactic acid or poly(L-lactic acid/glycolic acid) copolymer, and poly(DL- or L-lactic acid)-polyethylene glycol block copolymer or poly(DL- or L-lactic acid/glycolic acid)-polyethylene glycol block copolymer, is excellent in sustained release property of an active ingredient, further excellent in retainability in blood, reduces side effects, and especially has extremely remarkable sustainability in medicinal effect.