Patent SG-11201811342R-A (SG)
Title: Cartridge assembly
Inventor: LEMOINE RICHARD L
IPC: G01N35/00
Filed: 2017-10-11
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#111011110111010101111101 110 1 0011101M 0101111110011 1111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/071467 Al 19 April 2018 (19.04.2018) WIP0 1 PCT (51) International Patent Classification: trial Park El, North Tech Lobby 3, #02-13/18, Singapore G01N 33/48 (2006.01) G01N 35/00 (2006.01) 757715 (SG). BOIL 3/00 (2006.01) Cl 2M 3/00 (2006.01) (72) Inventors: LEMOINE, Richard L; 5200 Illumina Way, (21) International Application Number: San Diego, California 92122 (US). OSMUS, James; 5200 PCT/US2017/056032 Illumina Way, San Diego, California 92121 (US). LIN, Sz-Chin Steven; 5200 Illumina Way, San Diego, Califor- (22) International Filing Date: nia 92122 (US). ANG, Beng Keong; 29 Woodlands Indus- 11 October 2017 (11.10.2017) trial Park El, North Tech Lobby 3, #02-13/18, Singapore (25) Filing Language: English 757716 (SG). (26) Publication Language: English (74) Agent: WU, Bruce; 5200 Illumina Way, San Diego, Cali- (30) Priority Data: fornia 92122 (US). 62/408,631 14 October 2016 (14.10.2016) US (81) Designated States (unless otherwise indicated, for every 2017959 08 December 2016 (08.12.2016) NL kind of national protection available): AE, AG, AL, AM, (71) Applicants: ILLUMINA, INC. [US/US]; 5200 Illumina AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, Way, San Diego, California 92122 (US). ILLUMINA, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, SINGAPORE PTE. LTD. [SG/SG]; 29 Woodlands Indus- HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (54) Title: CARTRIDGE ASSEMBLY = = 102 200 = = — — 0 116 = 101 122 _ = 104 ' : 4 1. 400 = = 500 123 ) pe = = 0,.... . 124 = 406 1 ......0- --- \"'\" W\" --- IIL! ...4 .. t- ,, _ ,--- ••••• --- -— 124 = 108 106 _ ,-1 FIGURE 'IA Ir- (57) : A cartridge assembly that comprises a housing, including a flow cell chamber to receive a flow cell, and a well plate 7 1. having liquid wells to receive desired amounts of liquids. The well plate includes a valve station, a pump station and a fluidics analysis Il station, and channels associated therewith. A pump assembly to manage fluid flow through the channels between the pump station and Ir -- - the fluidics analysis station. A rotary valve assembly that includes a rotor shaft and rotor valve positioned to rotate about a rotational 0 ---. axis and to selectively couple the wells to the pump station. The rotor shaft includes a dual spline configuration at the distal end thereof. *1: The 1-1 dual spline configuration has first and second sets of splines. The first set of splines forms a drive interface and the second set of c;;;;) splines forms a position encoding interface. ei C [Continued on next page] WO 2018/071467 Al MIDEDIMOMOIDEIREIDIONOMMIEINHINVOIMIE KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.1700) Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))