baber/WOPTO huggingface dataset:
Patent RU-2754467-C2 (RU)
Title: COMPLETELY SCALABLE METHOD FOR PRODUCING rAAV BASED ON COLUMNS
Inventor: QU GUANG
IPC: A61K38/46
Filed: 2017-03-31
Granted: 2021-09-02
Abstract: FIELD: biochemistry.SUBSTANCE: method for purification of particles of a recombinant vector of an adeno-associated virus (hereinafter – rAAV) is described, including stages of: (a) collecting cells and cell culture supernatant containing particles of the rAAV vector to obtain a collection; (b) optionally, concentrating the specified collection obtained at stage (a) to obtain a concentrated collection; (c) lysing the specified collection received at stage (a), or the specified concentrated collection received at stage (b), to obtain lysate; (d) processing lysate obtained at stage (c) to reduce the content of contaminating nucleic acid in lysate and, thus, to obtain lysate with the reduced content of nucleic acid; (e) filtering the specified lysate with the reduced content of nucleic acid obtained at stage (d) to obtain purified lysate and, optionally, dilute the specified purified lysate to obtain diluted purified lysate; (f) subjecting the specified purified lysate or diluted purified lysate obtained at stage (e) to anion exchange chromatography on columns to obtain column eluate consisting of rAAV vector particles, and, optionally, concentrating the specified column eluate to obtain concentrated column eluate; (g) subjecting the specified column eluate or the specified concentrated column eluate obtained at stage (f) to exclusion column chromatography to obtain the second column eluate consisting of rAAV vector particles, and, thus, separating rAAV vector particles and protein impurities and, optionally, diluting the specified second column eluate to obtain diluted second column eluate; (h) subjecting the specified second column eluate or the specified diluted second column eluate obtained at stage (g) to cation exchange chromatography on columns to obtain the third column eluate consisting of rAAV vector particles, and, thus, separating rAAV vector particles and protein or other industrial impurities and, optionally, concentrating the specified third column eluate to obtain concentrated third column eluate; and (i) filtering the specified third column eluate or the specified concentrated third column eluate obtained at stage (h), and, thus, obtaining purified rAAV vector particles.EFFECT: invention makes it possible to achieve significant amount of AAV particle yield.74 cl, 3 dwg
Patent RU-2742589-C2 (RU)
Title: Комплект для изготовления термостатического элемента
Inventor: ZHAGE FREDERIK
IPC: F03G7/06
Filed: 2017-05-24
Granted: 2021-02-08
Abstract: Изобретение относится к комплекту для изготовления термостатического элемента, включающего в себя чашку с термически расширяемым материалом, поршень, установленный с возможностью перемещения вдоль оси (X-X) под воздействием термически расширяемого материала в направляющей (40), приспособленной для крепления к чашке, и буфер (60) из эластомерного материала, приспособленный для размещения между термически расширяющимся материалом и поршнем. Направляющая имеет канал (41), сцентрированный относительно оси и имеющий первый участок (41.2) постоянного сечения, второй участок (41.1), приспособленный для приема поршня и имеющий постоянное поперечное сечение меньше поперечного сечения первого участка канала, и третий участок (41.3), непрерывно соединяющий первый и второй участки канала. В соответствии с изобретением буфер имеет первый и второй концевые участки (62, 61), которые в собранном состоянии термостатического элемента расположены в первом и втором участках канала соответственно, независимо от поступательного положения поршня, а также переменный участок (63), соосно соединяющий первый и второй концевые участки. Перед сборкой буфера с остальными компонентами термостатического элемента переменный участок (63) по меньшей мере локально тоньше первого концевого участка, так что в собранном состоянии термостатического элемента переменный участок проходит от первого до второго участка канала через третий участок канала, частично снимая внутренние напряжения деформации в буфере при перемещении поршня. 14 з.п. ф-лы, 8 ил.
Patent RU-2755705-C2 (RU)
Title: Substituted derivatives of n-[2-(4-phenoxypiperidine-1-yl)-2-(1,3-thiazole-5-yl)ethyl]benzamide and n-[2-(4-benzyloxypiperidine-1-yl)-2-(1,3-thiazole-5-yl)ethyl]benzamide as p2x7 receptor antagonists
Inventor: PEVARELLO PAOLO
IPC: C07D417/14
Filed: 2017-08-09
Granted: 2021-09-20
Abstract: FIELD: pharmaceutics.SUBSTANCE: invention relates to specific compounds, which are substituted phenoxy- and benzyloxy-piperidine corresponding to the structural formula (I). The invention also relates to a method for producing compounds according to the invention and a pharmaceutical composition based on such compounds.EFFECT: compounds according to the invention are intended for the use in the treatment or prevention of diseases related to P2X7 receptor activity.5 cl, 1 dwg, 6 tbl
Patent RU-2748416-C2 (RU)
Inventor: NI CHUNJIAN
IPC: D01D5/24
Filed: 2017-12-22
Granted: 2021-05-25
Abstract: Изобретение относится к полому полиэфирному филаментному волокну, имеющему полую гофрированную форму, и к способу его изготовления, где полое волокно пригодно для изготовления волокнистого наполнителя из филаментного волокна. Заявленное волокно содержит полость в поперечном сечении, составляющую в диапазоне от 20,0 до 45,0%, и имеет трехмерную гофрированную форму в естественном состоянии. Гофрированная форма имеет радиус кривизны, составляющий в диапазоне от 10,0 до 50,0 мм. Заявленное волокно пригодно для переработки в распушенную обработанную ленту, обладающую большой распушенностью (объемностью), которую можно использовать в качестве волокнистого наполнителя из филаментного волокна. 2 н. и 5 з.п. ф-лы, 4 ил., 3 табл., 25 пр.
Patent RU-2750643-C2 (RU)
Inventor: Benkovich Nikita Dmitrievich
IPC: H04L47/2475
Filed: 2019-07-17
Granted: 2021-06-30
Abstract: FIELD: information security tools.SUBSTANCE: method is used, in which: at least two characteristics of an email are passed to the classifier, the verification of which by the method of signature analysis gave a negative result; using a classifier using machine learning methods, the degree of similarity of the received characteristics of an email with similar characteristics of emails previously recognized as spam is determined by signature analysis; the email is placed in temporary quarantine if the said degree of similarity exceeds the established threshold; before the expiration of the time allotted for quarantine, at least one more check of the email is conducted by signature analysis; the email is recognized as spam if the said check gave a positive result.EFFECT: technical result is reducing the number of spam email omissions by sending the email to quarantine for a time sufficient to issue the corresponding signature.7 cl, 4 dwg
Patent RU-2766123-C2 (RU)
Title: Methods and apparatus for transmitting notifications alerting of a hazard applying discrete-input channels
Inventor: AMIRTASAMI Stenli Feliks
IPC: G05B19/042
Filed: 2018-01-31
Granted: 2022-02-08
Abstract: FIELD: data transmission.SUBSTANCE: invention relates to technological processes. The apparatus for transmitting notifications alerting of a hazard applying discrete-input channels comprises a field apparatus for controlling the technological process of the technological set, provided with a digital valve controller. The digital controller comprises an apparatus for monitoring a parameter of the technological process; an emergency signal detector; an emergency state setter; a discrete-output channel and a host apparatus. The host apparatus has a discrete-input channel for receiving an emergency signal notification and a status notification from the digital valve controller.EFFECT: transmission of notifications is improved.20 cl, 6 dwg
Patent RU-2748252-C2 (RU)
Title: Method for destruction of medial branch of spinal nerve
Inventor: Byvaltsev Vadim Anatolevich
IPC: A61B17/00
Filed: 2019-10-15
Granted: 2021-05-21
Abstract: FIELD: medicine. 
     SUBSTANCE: invention relates to medicine, namely to neurosurgery and vertebrology, and can be used to treat destruction of the medial branch of the spinal nerve in patients with osteochondrosis of the lumbosacral spine, accompanied by severe recurrent facet syndrome. In surgical treatment with posterolateral access, a puncture is performed in the projection of the facet joint until the needle with a mandrel stops at the junction of the transverse process and the facet joint under X-ray control. Then the mandrel is replaced with a fiber-optic light guide and the medial branch of the spinal nerve is destroyed by pulsed laser radiation in the 970 nm mode 3 times with an interval of 5 seconds with a gradual reverse traction of the mandrel with the light guide by 3 mm along the lateral surface of the facet joint. The laser radiation frequency is 9 Hz, the power is 3 W in the total heat release dose of 100 J. The exposure time is no more than 15 seconds. 
     EFFECT: method provides increased period of remission of the disease, decreased damage to surrounding tissues during surgical treatment due to the destruction of the medial branch of the spinal nerve by pulsed laser radiation in the specified mode. 
     1 cl, 1 tbl, 1 ex, 4 dwg
Patent RU-2767144-C2 (RU)
Inventor: KARCZEWICZ MARTA
IPC: H04N19/577
Filed: 2018-03-22
Granted: 2022-03-16
Abstract: Изобретение относится к вычислительной технике. Технический результат заключается в повышении эффективности кодирования. Способ декодирования видеоданных из кодированного потока видеобитов, в котором формируют, с использованием извлечения векторов движения на стороне декодера (DMVD), множество извлеченных векторов движения; определяют первый извлеченный вектор движения и второй извлеченный вектор движения из множества извлеченных векторов движения на основе показателя затрат, что содержит этап, на котором определяют то, что первый извлеченный вектор движения и второй извлеченный вектор движения удовлетворяют по меньшей мере одному ограничению на взаимосвязь между первым извлеченным вектором движения и вторым извлеченным вектором движения; и декодируют текущий блок с использованием определенных первого извлеченного вектора движения и второго извлеченного вектора движения, которые удовлетворяют по меньшей мере одному ограничению на взаимосвязь, с использованием бипрогнозирования. 4 н. и 16 з.п. ф-лы, 4 табл., 17 ил.
Patent RU-2753577-C2 (RU)
Inventor: CHOI YOUNG-HWAN
IPC: F24H7/02
Filed: 2018-03-02
Granted: 2021-08-17
Abstract: Изобретение относится к котлу для горячей воды накопительного типа, содержащему вихревую направляющую часть. Котел содержит корпус, имеющий разделительную часть в нем и снабженный отдельной огневой камерой, расположенной над разделительной частью, и горелку, обеспечивающую подачу пламени в огневую камеру. Котел содержит множество огневых труб, имеющих первую сторону, соединенную с нижней поверхностью огневой камеры, и вторую сторону, проходящую вниз в разделительную часть. Котел содержит вихревую направляющую часть, имеющую спиральную часть, расположенную по спирали вдоль вертикального направления корпуса в разделительной части. Спиральная часть расположена по спирали вокруг центрального прохода, расположенного в вертикальном направлении по центру разделительной части для направления воды, а центральный проход представляет собой пространство, выполненное единым целым с разделительной частью. Кроме того, котел содержит выпускную часть, расположенную в положении под корпусом и соединенную с огневыми трубами. Техническим результатом является улучшение эффективности теплообмена огневых труб, а также обеспечение эффекта предотвращения скопления накипи на части нижней поверхности огневой камеры. 8 з.п. ф-лы, 9 ил.
Patent UA-76916-C2 (UA)
Title: Method for producing bimetallic plate of current-collecting device of electric locomotive
Inventor: TRAKSHYNSKYI BORYS ROMANOVYCH
IPC: B22D19/16
Filed: 2005-04-18
Abstract: The invention relates to machine building and concerns the technology of production of bimetallic current-collecting device of electric locomotive. A bimetallic plate is manufactured by method of furnace hard-facing on the steel strip of composite material from copper, graphite and lead. In this case, hard-facing is conducted in the airtight multiple steel chill mold at a temperature of 350 - 500 °C. The method allows to obtain a bimetallic plate, which is characterized by low coefficient of friction and high strength.
Patent UA-92715-C2 (UA)
Title: Electronic data interchange-based system of provision of data for process execution
Inventor: WIEPPERSTEG HEINZ-HEMANN
IPC: H04L29/08
Filed: 2005-09-02
Abstract: The invention relates to electronic data interchange-based system (1) of provision of data (37, 39) for process execution (2) where information support (34) is carried out with usage of at least one applied program (24) and the applied program (24) generates situational data (37, 39). The information support (34) for process execution (2) is carried out with usage of at least one applied program (24) which prepares process data (38, 39) and planning a technological circuit thereby a system (1) user (27, 40) of information execution is considerably unloaded from qualified data generation (39).
Patent UA-82523-C2 (UA)
Title: Method for determination of kneecap position
Inventor: HOSHKO VOLODYMYR YURIOVYCH
IPC: A61B5/103
Filed: 2005-12-22
Abstract: The invention relates to medicine, in particular to orthopaedy, and concerns a method for determination of kneecap position level. For that end on the roentgenogram of the knee joint in lateral projection a center of kneecap is determined, the axis of tibia is drawn, then two parallel lines are drawn at right angle to the axis, one of which is passed through the apex of head of fibula and the second one is tangent to the end of medial process of femur. Thereafter the center point of kneecap is joined with the point of intersection of line drawn through the apex of head of fibula with external cortical plate of tibia, and according to correlation of length of line segment formed between kneecap center and point of intersection with line drawn through the end of medial process to the length of line segment between two parallel lines an index of kneecap position level is determined. The value of this index in health is 1.5-1.6 with tolerance of 20%.
Patent UA-82530-C2 (UA)
Title: Method for water purification from manganese compounds
Inventor: HONCHARUK VLADYSLAV VOLODYMYROVYCH
IPC: C02F1/64
Filed: 2006-01-27
Abstract: A method for water purification from mangenese compounds comprises water filtration through manganese-containing charge. Grounded pyrolusite, is used as manganese-containing charge, previously treated with a polymer of organic or inorganic nature in quantity of 0.5-2.5 % of pyrolusite weight followed by the thermal treatment. This invention provides the increasing of specific volume of water, purified from manganese compounds, as well as amount of sorption volume of filtering material due to increase of structural stability of grounded pyrolusite.
Patent UA-84174-C2 (UA)
Title: Contact-less electromagnetic method for control of limiting stressedly deformed state of sheet materials
Inventor: SHOKAREV VIKTOR SEMENOVYCH
IPC: G01B7/16
Filed: 2006-05-29
Abstract: Contact-less electromagnetic method for control of limiting stressedly deformed state of sheet material is claimed, it is in fact that one places over controlled section of material differential electromagnetic transformer that includes cylindrical magnetic conductor with excitation winding placed on it, this is connected to source of alternating current, and measuring one connected to device for measurement and processing output signals, one displaces electromagnetic transformer with magnetic conductor normally to surface of controlled section with measurement with measuring and processing device the value of extreme output signalof transformer. After measurement ofone performs following continuous control, control time is divided to equal intervals:. Interval, where- time of interaction of section of controlled material with differential electromagnetic transformer;- time of interaction of section of controlled material with mechanical stresses in it. After each time intervalone measures output limiting signal of transformer. By extreme signal obtained,in device for measurement and processing one determines dependence. If the dependence is smooth controlled material is in pre-limiting stressedly deformed condition. If dependencehas maximaand minimaof change of amplitude of output signals at inclined section of dependence, material is in pre-boundary stressedly-deformed state. By value of limiting output signalon inclined section of dependenceon basis of calibration complete deformation dependencesandone determines value of limiting stressor limiting elongation.
Patent UA-90119-C2 (UA)
Title: Wall lining and efficient method for mounting
Inventor: JORET LAURENT
IPC: E04F13/08
Filed: 2005-12-06
Abstract: The invention relates to a method of lining a wall (1). According to the invention, a lining (8) support element (6) is positioned on a spacer element (5), such that the two elements are engaged with one another. Subsequently, the position of the support element (6) is adjusted by moving same in translation on the spacer element (5), said movement being blocked and unblocked by rotating the support element (6) using a single lever (64) which is solidly connected thereto and which, in the final blocking position, butts against the lining (8). The invention also relates to the wall lining (1) thus obtaining and to the associated fixing kit.
Patent UA-88227-C2 (UA)
Title: Apparatus for cultivation of microorganisms
Inventor: PIDDUBNYI VOLODYMYR ANTONOVYCH
IPC: C12M1/02
Filed: 2008-02-07
Abstract: An apparatus for cultivation of microorganisms consists of reactor, airlift ventilator, cooling jacket, jets for supply of nutrition and removal of cultural medium, and discharge flue.According to the invention, the bottom horizontal part of air flue is made in the form of ejection device, the low-pressure chamber of which is connected with circulation pipe, cut into reactor on high of turgent layer of gas-liquid cultural medium.
Patent UA-96607-C2 (UA)
Title: Fitting for windows or doors
Inventor: MANFRED LUDWIG
IPC: E05B17/00
Filed: 2009-03-31
Abstract: Fitting for windows or doors (1) for bringing into operation of mechanism integrated into a window or a door has a support element (4) that is intended for fixation on the window or a door, and a handle (6) that is installed on the support element (4) or in it without possibility of displacement in axial direction, though with possibility of turn. The polyhedron (9) is for mechanical coupling of the set (1) with a mechanism integrated to a window or a door, at that the polyhedron (8) acts as a section (8A) of the polyhedron out of the support element (4). By means of the coupling system (10) formed between the handle (6) and the polyhedron (8) possibility of transfer of torque from the handle (6) to the polyhedron (8) is provided, though transfer from the polyhedron (8) to the handle (6) is blocked. To provide possibility of automated account of different thicknesses of the frame or profile at installation to the window or door there is provided that length (L) of the section (8a) of the polyhedron that goes out of the support element (4) and goes into the frame of the window or door at installation of the support element (4) to the window or door is automatically controlled, at that the polyhedron (8) is directed in the system (10) of coupling with possibility of shift in long direction and without possibility of turn and goes through it to the handle (6).
Patent UA-98942-C2 (UA)
Title: Single packaged detergent-coated composition and process for its preparation
Inventor: BELTEN-CASTEEL SASCHA
IPC: C11D17/00
Filed: 2007-09-19
Abstract: The present invention relates to a coated detergent and/or additive composition e.g. for the dish washing or laundry machine or water softener tablets coated with a water soluble /dissolvable /dispersible material and « process of manufacturing therof.
Patent UA-97260-C2 (UA)
Title: Drive mechanism for use in a drug delivery device, drug delivery device and method of manufacturing or assemblage of the drug delivery device
Inventor: BOYD MALCOLM
IPC: A61M5/315
Filed: 2007-11-08
Abstract: A drive mechanism for use in a drug delivery device comprising: a housing; a drive member movable longitudinally and non-rotatable with respect to the housing; a piston rod that is non-rotatable with respect to the housing and having at least one set of teeth, a rotating means releasably engaged with the piston rod and engaged to the drive member and engaged to the housing I wherein the rotating means is selected from the group of (I) to (ii), (i) a gear the axle of which is engaged with the set of teeth of the ' piston rod, (ii) a pulley comprising a belt and a wheel the axle of which is engaged with the set of teeth of the piston rod; characterized in that, a) when the drive member moves proximally with respect to the housing the rotating means moves proximally with respect to the piston rod; b) when the drive member moves distally the rotating means moves distally displacing the piston rod towards the distal end of the device.
Patent UA-94378-C2 (UA)
Title: Feed for bee families-female bee tutors
Inventor: SHEREMETA VIKTOR IVANOVYCH
IPC: A01K53/00
Filed: 2009-07-17
Abstract: The invention relates to a feed for bee familes-female bee tutors including a mixture of biologically active substances diluted in sugar syrup. The feed comprises the following constituents in an equivalent of % / kg of sugar:
Patent UA-94151-C2 (UA)
Title: Method for making condensed hydrolyzed unskimmed milk
Inventor: YERESKO HEORHII OLEKSIIOVYCH
IPC: A23C9/18
Filed: 2009-08-19
Abstract: The invention relates to a method for making condensed hydrolyzed unskimmed milk, providing pasteurizing a normalized mixture in the spring-summer period at a temperature of 106±2 °C, and in autumn-winter period at a temperature of 102±2 °C with further cooling up to a temperature of 8-10 °C such that lactose hydrolysis is carried out with a time-exposure of 20-30 hours applying an enzyme preparation in an amount of 0.005-0.01 % of the weight of the normalized mixture up to achieving the degree of hydrolysis at the level of 70-75 %, inactivating the enzyme. After the inactivation of the enzyme sugar syrup and/or milk-sugar syrup and/or sugar are prepared and added, after what the milk is condensed, cooled up to a temperature of 18-20 °C and fed for packing.
Patent UA-104752-C2 (UA)
Title: Process for processing coal-tar pitch
Inventor: ZOLOTARIOV IVAN VASYLIOVYCH
IPC: C10C1/00
Filed: 2011-09-05
Abstract: The invention relates to by-product coking industry. A process for processing coal-tar pitch is characterized in that during rectification of coal-tar pitch a chemically active additive – ammonium sulfate in the amount of 0.2-0.3 % of mass of processed pitch is introduced in the form of an aqueous solution, wherein pitch rectification is carried out according to continuous scheme. The invention enables to increase the yield of medium temperature peck at continuous rectification of coal-tar pitch without using expensive external chemical agents, additional equipment, and complex technologic stages.
Patent UA-106886-C2 (UA)
Title: Спосіб одержання 1-бензил-3-гідроксиметил-1h-індазолу і його похідних та проміжні сполуки магнію
IPC: C07F3/00
Filed: 2010-07-28
Abstract: Даний винахід стосується способу одержання 1-бензил-3-гідроксиметил-1H-індазолу формули (II) для застосування у наступному способі одержання 1-бензил-3-гідроксиметил-1Н-індазолу формули (І).