baber/WOPTO huggingface dataset:
Patent AT-E381617-T1 (AT)
Inventor: SZKUDLINSKI MARIUSZ
IPC: C12N15/09
Filed: 1996-05-08
Granted: 2008-01-15
Abstract: The invention is directed toward a human glycoprotein hormone having at least one, two, three, four or five basic amino acids in the alpha -subunit at positions selected from the group consisting of positions 11, 13, 14, 16, 17 and 20. The invention is also directed to a human glycoprotein where at least one of the amino acids at positions 58, 63 and 69 of the beta -subunit of the human thyroid stimulating hormone are basic amino acids. The invention is further directed to a modified human glycoprotein hormone having increased activity over a wild-type human glycoprotein hormone, where the modified human glycoprotein hormone comprises a basic amino acid substituted at a position corresponding to the same amino acid position in a non-human glycoprotein hormone having an increased activity over the wild-type human glycoprotein hormone. The invention is also directed to a method of constructing superactive nonchimeric analogs of human hormones comprising comparing the amino acid sequence of a more active homolog from another species to the human hormone, substituting selected amino acids in the human hormone with the corresponding amino acids from the other species, determining the activity of the substituted human hormones, and selecting superactive analogs from the substituted human hormones. The invention is also directed to nucleic acids encoding the modified human glycoprotein hormones, vectors containing those nucleic acids, and host cells containing those vectors.
Patent AT-E288271-T1 (AT)
Inventor: SHERMAN BERNARD CHARLES
IPC: A61K31/55
Filed: 1996-07-30
Granted: 2005-02-15
Abstract: There is disclosed a stable pharmaceutical solid composition comprising enalapril as the sodium salt, which is made by the steps of: i) mixing enalapril maleate with a carrier, an alkaline sodium compound, and water; ii) drying the wet mass; iii) further processing the resultant dried mass into tablets. When the water is added in the aforesaid process, an acid-base reaction occurs which converts the enalapril maleate into the more stable enalapril sodium salt.
Patent AT-E295892-T1 (AT)
Inventor: GRAY JOHN CLINTON
IPC: C07K14/415
Filed: 1996-08-28
Granted: 2005-06-15
Abstract: A polypeptide amino acid sequence capable of targeting the plastid inner envelope membrane of a plant, and a nucleotide sequence therefor, are described, as well as a chimaeric gene comprising a gene promoter, a nucleotide sequence encoding a polypeptide capable of targeting the plastid inner envelope membrane of a plant, or a variant, derivative or homologue thereof, a coding sequence and a terminator sequence. A method of transforming plants, such as potato and tobacco, using the targeting sequence so as to increase starch production is also described. The targeting sequence can be used in many other applications.
Patent AT-E219386-T1 (AT)
Inventor: SARTORE ALMERIGO
IPC: A63B21/008
Filed: 1996-11-07
Granted: 2002-07-15
Abstract: A braked roller device for cycling training includes a roller (2) that is rotatably mounted on a support (3) with a substantially horizontal axis (a), and anchored to a stand (4) that is suitable to support the driving wheel (R) of a bicycle so that it is raised from the ground and in contact with the roller (2). A brake (17) is rigidly coupled to the support (3) and acts on the roller (2) to simulate resistance to forward motion. The brake (17) includes a rotor with smooth surfaces, which is rigidly coupled to the roller (2) and is accommodated in a chamber that is closed hermetically and partially filled with a viscous fluid. The rotor is constituted by one or more disks with substantially flat and parallel side faces made of relatively rigid material, each part being optionally provided with two or more lateral holes for the controlled flow of the fluid.
Patent AT-E203524-T1 (AT)
Inventor: LOHMANN JEAN-JACQUES MARCEL
IPC: A61K31/517
Filed: 1996-12-13
Granted: 2001-08-15
Abstract: The invention relates to quinazoline derivatives of the formula: [wherein: Y1 represents -O-, -S-, -CH2-, -SO-, -SO2-, -NR5CO-, -CONR6-, -SO2NR7-, -NR8SO2- or -NR9- (wherein R5, R6, R7, R8 and R9 each independently represents hydrogen, alkyl or alkoxyalkyl); R1 represents hydrogen, hydroxy, halogeno, nitro, trifluoromethyl, cyano, alkyl, alkoxy, alkylthio, amino or alkylamino. R2 represents hydrogen, hydroxy, halogeno, alkyl, alkoxy, trifluoromethyl, cyano, amino or nitro; m is an integer from 1 to 5; R3 represents hydroxy, halogeno, alky, alkoxy, alkanoyloxy, trifluoromethyl, cyano, amino or nitro; R4 represents a group which is or which contains an optionally substituted pyridone, phenyl or aromatic heterocyclic group] and salts thereof; processes for their preparation and pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent AT-E299712-T1 (AT)
Inventor: FANGET BERNARD
IPC: A61K31/00
Filed: 1996-12-20
Granted: 2005-08-15
Abstract: Stabilizers for live vaccines and attenuated mono- or multivalent live vaccines, stabilized vaccines containig such stabilizers, and methods for preparing such vaccines, are disclosed. Said stabilizers for vaccines containing one or more attenuated live viruses include one or more components selected from each of the following groups: amino acids, disaccharides, polyalcohols and buffer solutions, with the proviso that one component selected from the disaccharide group is saccharose.
Patent AT-E242898-T1 (AT)
Inventor: KAPLAN ERAN
IPC: G02B21/36
Filed: 1996-12-13
Granted: 2003-06-15
Abstract: A method of mapping areas of a slide includes the steps of selectively illuminating the slide from a first light source oriented generally obliquely to the surface of the slide, obtaining a first image of the slide illuminated by the first light source, selectively illuminated the slide from a second light source providing generally scattered light, obtaining an image of said second image illuminated by the second light source, and generating a map of areas of significance based on the first and second images.
Patent AT-E177303-T1 (AT)
Inventor: PAETZOLD DIETER
IPC: A47L13/59
Filed: 1997-01-14
Granted: 1999-03-15
Abstract: The water-drainage pressure applicator (7) and a pressure application unit (15) are concavely shaped facing each other and have interfitting holes (19)or tines (18). An operating lever (10) and pressure application unit are in the form of a single-armed lever containing a cam (21) for connecting it to the pressure unit. The squeezer consists of a base frame (2) for adapting onto a container (1). The operating lever is mounted on the transition (9) between the base frame and the pressure applicator and unit.
Patent AT-E246907-T1 (AT)
Inventor: COSTIN JOHN A
IPC: A61B18/00
Filed: 1992-01-02
Granted: 2003-08-15
Abstract: A method and apparatus for operating on the human eye detects changes in load, more specifically, mechanical impedance, of the transducer (300) and controls aspiration based on the load changes. A change from a lower load to a higher load indications that harder tissue is being encountered and accordingly causes aspiration amount to increase. Conversely, a change from a higher load to a lower load indicates that aspiration amount should be quickly decreased since the tissue which is being encountered is softer. One way to detect the impedance is by a sensor (1008), i.e., a piezoelectric element coupled to the operating needle detecting the movement thereof. <IMAGE>
Patent AT-E229654-T1 (AT)
Inventor: NANDRA NAVRAJ
IPC: G06K7/00
Filed: 1997-02-05
Granted: 2002-12-15
Abstract: The oscillator system forms part of a base station (13), which has regulation (21,22) and command (24) mechanisms, and decoding circuits (25,26,27). The oscillator mechanism is voltage commanded and phase adjusted so that the command frequency signal determined by the base station is adapted to the antenna system.
Patent AT-E202043-T1 (AT)
Inventor: KOEHLER GISBERT
IPC: B60R1/06
Filed: 1997-10-24
Granted: 2001-06-15
Abstract: The mirror has a mirror housing (10) containing a mirror glass (20) which can be adjusted relative to at least one setting axis via an electric setting drive, the housing itself rotated about a second axis (5) via a pivot mounting provided by a mounting foot (2), attached to the vehicle bodywork. A single electric setting motor (40) has a first setting element (44) which is coupled directly to the pivot mounting and a second setting element which is electromagnetically coupled to the first setting element for adjusting the mirror glass via an intermediate linkage.
Patent AT-E249960-T1 (AT)
Inventor: MILLS CHRISTOPHER JAMES
IPC: B62B9/18
Filed: 1997-10-01
Granted: 2003-10-15
Abstract: A suspension assembly for a wheeled conveyance comprises suspension arms (35, 37) pivotably mounted on a chassis (1) and extending in forward and rearward directions in the region of opposite sides of the chassis. Each suspension arm has a wheel (43, 45) rotatably mounted at the free end thereof. Spring means (51) is disposed in the region of each side of the chassis and acts between the forwardly and rearwardly extending suspension arms (35, 37) in such a way that the free ends thereof tend to pivot towards each other. According to the invention, means (69, 59) is provided for limiting lateral movement of the suspension arms (35, 37) relative to each other. <IMAGE>
Patent AT-E185768-T1 (AT)
Inventor: HAAKE HINRICH
IPC: A01F25/16
Filed: 1997-02-11
Granted: 1999-11-15
Abstract: PCT No. PCT/EP97/00614 Sec. 371 Date Aug. 5, 1998 Sec. 102(e) Date Aug. 5, 1998 PCT Filed Feb. 11, 1997 PCT Pub. No. WO97/29984 PCT Pub. Date Aug. 21, 1997A process for removing bulk material from a gastight silo. At the silo outlet (10) a container is connected in a gastight arrangement with an input valve and an output valve (12, 13) through which the container is evacuated before the bulk material is removed. In addition, a gastight membrane (20) is fitted in the container (11) in order to seal off the bulk material from the surroundings during the initial stages of the removal operation.
Patent AT-E253733-T1 (AT)
Inventor: BENGTSSON TORD
IPC: H01F29/04
Filed: 1997-03-10
Granted: 2003-11-15
Abstract: PCT No. PCT/SE97/00402 Sec. 371 Date Nov. 12, 1998 Sec. 102(e) Date Nov. 12, 1998 PCT Filed Mar. 10, 1997 PCT Pub. No. WO97/34161 PCT Pub. Date Sep. 18, 1997A method for monitoring an on-load tap changer wherein the recording of sound and its conversion into a sound signal are initiated at the beginning of a connection operation of the tap changer and the sound signal is rectified, converted into a signal envelope, sampled digitally and continuously evaluated with respect to the condition of the tap changer by comparing the envelope with at least one fixed or one continuously updated reference envelope. The comparison is carried out selectively by calculating a dimensionless comparison figure Ti which is based on a quantity measure and a variation measure.
Patent AT-E511796-T1 (AT)
Inventor: KOTULA FRANK
IPC: A61B17/12
Filed: 1997-04-14
Granted: 2011-06-15
Abstract: The present invention provides a method of forming a medical device and medical devices which can be formed in accordance with the method. In one embodiment, the method includes the steps of a) providing a metal fabric formed of a plurality of strands formed of a metal which can be heat treated to substantially set a desired shape; b) deforming the metal fabric to generally conform to a surface of a molding element; c) heat treating the metal fabric in contact with the surface of the molding element to substantially set the shape of the fabric in its deformed state; and d) removing the metal fabric from contact with the molding element. The resulting metal fabric will define a medical device which can be collapsed for passage through a catheter or the like for deployment in a channel of a patient's body. Medical devices made in accordance with this method can have varying structures.
Patent AT-E190780-T1 (AT)
Inventor: WEINMEIER HARALD
IPC: H02J1/10
Filed: 1997-07-10
Granted: 2000-04-15
Abstract: The invention relates to a switched mode power supply system with a transformer (Tr) which has a primary winding (LP) and at least one secondary winding (LS) and an auxiliary winding (LH). Said power supply system also has a switch (S) which is controlled via a triggering circuit (A) by way of which the primary winding is at a dc input voltage (UE), a rectifier (D1) which is connected downstream of the secondary winding, has filter means (C1) for producing a dc output voltage (UA) and has control means (K1) for producing a first regulation variable (St1) for the triggering circuit (A) in relation to the deviation of the output voltage from a first theoretical value (URef1). The pulse duty factor and/or the frequency of the triggering signal of the controlled switch depends on the regulation variable. Said system also has an auxiliary rectifier (D2; Glr) for production of an auxiliary direct voltage (UH) for the triggering circuit or other consumers, an auxiliary control (K2) for producing a second regulation variable (St2) for the triggering circuit (A) in relation to the deviation of the auxiliary direct voltage (UH) from a second theoretical value (URef2), and a selector module (AS) for preferred supply of the regulation variable of each regulator to the triggering circuit (A), the actual value thereof being below the associated theoretical value.
Patent AT-E215815-T1 (AT)
Inventor: SAETTONE MARCO FABRIZIO
IPC: A61K9/00
Filed: 1997-07-25
Granted: 2002-04-15
Abstract: Mucoadhesive antimicrobial complexes of polycarbophil, i.e. a cross-linked polyacrylic acid with bioadhesive properties, and an imidazole or triazole derivative with antifungal or antiprotozoal activity, in its basic form, for use in the topical treatment of mucosal affections. The complexes are obtainable by dissolving each of the two starting products in a common solvent, then joining together the two solutions in relative amounts such as to contain the same number of equivalents of the two starting products, evaporating the solvent and then drying and, if required, pulverizing and sieving the product so obtained. Particularly preferred are formulations in gel in propylene glycol comprising an econazole-polycarbophil or omoconazole-polycarbophil complex, with an excess of polycarbophil, together with pharmaceutically acceptable carrier and excipient substances, for use as sustained release antifungals for vaginal administration.
Patent AT-E205198-T1 (AT)
Inventor: KITAMURA SATOSHI
IPC: C07D295/22
Filed: 1997-12-05
Granted: 2001-09-15
Abstract: PCT No. PCT/JP97/04451 Sec. 371 Date Jun. 14, 1999 Sec. 102(e) Date Jun. 14, 1999 PCT Filed Dec. 5, 1997 PCT Pub. No. WO98/25914 PCT Pub. Date Jun. 18, 1998Hydrates of N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide, which are stable against heat, light, and humidity, are described. The material is easy to handle under ordinary interior humidity conditions. N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate is useful as a medicament in the treatment of amnesia and senile dementia.
Patent AT-E345203-T1 (AT)
Inventor: TREVISIOL EZIO
IPC: B24B23/02
Filed: 1998-05-08
Granted: 2006-12-15
Abstract: Portable electro-manual smoothing planer, of the type in which it comprises:  two planes for the resting on the surface to be worked (3, 4) of which: a fixed rear resting plane (3) and a movable (1) front (4) resting plane, at least retracted respect to the plane of the first one (3); a tool-holder operating roll (13), placed between said two planes (3, 4), rotatably motorised on horizontal axis transversal respect to the advancement direction by manual thrust of said portable electro-manual smoothing machine (20-19, 9, 16, 8, 7), operator on the surface to be worked, with operating surface substantially around said fixed rear plane (4) a first control main handgrip (2) above said rear resting plane; operation electric control means (12) on said control handgrip (2); a second substantially knob-shaped handgrip (1), above said front resting plane (4), rotatably operable manually, for rotating axial means with resting screw to said front resting plane for lifting or lowering it respect to said rear resting plane (3), characterised in that said tool-holder operating roll (13) is structured for housing in it at least an abrasive coating (22).  <IMAGE>
Patent AT-E219762-T1 (AT)
Inventor: GERGELY GERHARD DR
IPC: A23L27/00
Filed: 1994-09-05
Granted: 2002-07-15
Abstract: Modified crystals of a solid, edible organic acid, especially citric acid, are prepared by coating the crystals with a layer of sodium citrate and drying. Also claimed are crystals of the solid edible organic acid which after coating with a layer of sodium-(Na-)citrate, are then coated with a further layer consisting of sodium bicarbonate and/or sodium carbonate.
Patent AT-E254507-T1 (AT)
Inventor: BLEH KLAUS
IPC: B03B5/00
Filed: 1998-08-29
Granted: 2003-12-15
Abstract: By feeding the raw material in the feed chute (4) in the direction of travel of the conveyor (2) and laying out the feed chute in a cascade-like manner in a number of steps (14), between which shower jets (5) wet the material, the clean and raw products remain separate. The plates forming each step are fitted with end plates which retain material at the rear, upper, end; the feed chute is fitted with a shaker motor (15) and an eccentrically running roller (13) agitates the conveyor band in the wash trough area (8).
Patent AT-E215060-T1 (AT)
Inventor: DI NAPOLI GUIDO
IPC: C07C/
Filed: 1998-12-23
Granted: 2002-04-15
Abstract: The present invention regards a process for the preparation of rhein and corresponding diacyl derivatives, in particular diacerein, via oxidation of aloe-emodin and its triacyl derivatives with salts of nitrous acid, possibly followed by acylation of the rhein thus obtained.
Patent AT-E343848-T1 (AT)
Inventor: CAIRE JEAN
IPC: H01H71/08
Filed: 1998-08-24
Granted: 2006-11-15
Abstract: The connecting comb section connects wires (b) on the different sections using protruding teeth connecting onto connecting positions, making assembly easy
Patent AT-E190114-T1 (AT)
Inventor: DOUVIER SERGE
IPC: A21C5/00
Filed: 1998-05-07
Granted: 2000-03-15
Abstract: The cover (B) is mounted on eccentric wheels (1) on a shaft (12) around which it moves to open or close the cover. The closed cover is locked in position by the movement of a piston (15), which acts against a cam (13), to rotate the shaft so the eccentric wheels push the cover forwards, pushing feet at its front (not shown) into hooks (21 and 22) in the rim of the vessel.
Patent AT-E286399-T1 (AT)
Inventor: MARCIANI DANTE J
IPC: A61K31/56
Filed: 1998-05-20
Granted: 2005-01-15
Abstract: The present invention is directed to novel chemical compounds in which a lipophilic moiety such as a lipid, fatty acid, polyethylene glycol or terpene is covalently attached to a non-acylated or desacylated triterpene saponin via a carboxyl group present on the 3-O-glucuronic acid of the triterpene saponin. The attachment of a lipophile moiety to the 3-O-glucuronic acid of a saponin such as Quillaja desacylsaponin, lucyoside P, or saponin from Gypsophila, Saponaria and Acanthophyllum enhances their adjuvant effects on humoral and cell mediated immunity. Additionally, the attachment of a lipophile moiety to the 3-O-glucuronic acid residue of non- or des-acylsaponin yields a saponin analog that is easier to purify, less toxic, chemically more stable, and possesses equal or better adjuvant properties than the original saponin.
Patent AT-E556315-T1 (AT)
Inventor: SUNDBERG STEVEN
IPC: B01J19/00
Filed: 1998-06-04
Granted: 2012-05-15
Abstract: Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by sequentially blowing the fluid out through the substrate and replacing the removed fluid with an alternate fluid, or by displacing the fluid in part with additional fluid. In another aspect, microfluidic substrates have channels which varying in cross-sectional dimension so that capillary action spreads a fluid only within a limited portion of the channel network. In yet another aspect, the introduction ports may include a multiplicity of very small channels leading from the port to a fluid channel, so as to filter out particles or other contaminants which might otherwise block the channel at the junction between the channel and the introduction port.
Patent AT-E224133-T1 (AT)
Inventor: SCHRATTENECKER FRANZ
IPC: A01D41/14
Filed: 1998-11-09
Granted: 2002-10-15
Abstract: A front-mounted attachment (2) for harvester-threshers (1) for harvesting soy-beans and peas has a resiliently mounted additional cutting mechanism (4), whose cutter drive (5) can be derived from the drive of the cutting mechanism of the harvester-thresher (1). To ensure a simple and trouble-free operation, the cutter drive (5) includes an oil-bath transmission (6) to be connected to the drive of the cutting mechanism of the harvester-thresher (1) via a belt drive (7), which oil-bath transmission is mounted on a lateral runner (8) pivotally mounted at the cutting mechanism (10) of the harvester-thresher so as to be swivelled about a horizontal transverse axis (A) by a swivel arm (9).
Patent AT-E283405-T1 (AT)
Inventor: SCHNEIDER HORST
IPC: E04F11/116
Filed: 1999-01-08
Granted: 2004-12-15
Abstract: The steps have a horizontal step surface and a vertical front and rear outside surface. In side view the step has the shape of an inverted U with the two U-arms (7, 8) extending in the installed state of the step over the entire height (h) of the step. The two outside faces (3, 4) are formed as alternating visible surfaces with at least one having a projection (5, 6).  the insides of the U arms in the installed state of the step run inclined upwards and inwards
Patent AT-E280987-T1 (AT)
Inventor: BRAUN HANS-JOACHIM
IPC: G08G1/07
Filed: 1999-03-05
Granted: 2004-11-15
Abstract: The method involves detecting occupation of measurement cross-sections (6,9) around the management systems (1) and passing these to a controller (3) which derives control parameters for operating the management systems. Condition equations (B1-B3) are stored in a data base (15) associated with a control program. Rules (R1-R4) stored in the data base have three possible rule values per condition equation corresp. to true, false or any and resulting in the selection of an action (A1-A4). Parameter values are compared with threshold values according to the condition equations and the results stored. Truth values are compared with rule values and an action performed if all truth values corresp. to all rule values of an individual rule corresp. to this action.