baber/WOPTO huggingface dataset:
Patent JP-2000509271-A (JP)
IPC: C07K14/705
Filed: 1997-04-15
Abstract: The present invention relates to glial cell line-derived neurotrophic factor (GDNF), a potent neurotrophin that exhibits a broad spectrum of biological activities on a variety of cell types from both the central and peripheral nervous systems. The present invention involves the cloning and characterization of a high affinity receptor for GDNF. This molecule has been named GDNF receptor (GDNFR) since it is the first known component of a receptor system. Nucleic acid and amino acid sequences are described for GDNFR protein products. A hydrophobic domain with the features of a signal peptide is found at the amino terminus, while a second hydrophobic domain at the carboxy terminus is involved in the linkage of the receptor to the cell membrane. The lack of a transmembrane domain and cytoplasmic region indicates that GDNFR requires one or more accessory molecules in order to mediate transmembrane signaling. GDNFR mRNA is widely distributed in both nervous system and non-neural tissues, consistent with the similar distribution found for GDNF.
Patent JP-2000517415-A (JP)
Title: ホスホチロシン擬似物、該擬似物を同定するための方法及びその使用
IPC: G01N33/577
Filed: 1997-05-07
Abstract: (57)【要約】
本発明は、適当な分子構造物に取り込まれたときに、未変性のホスホチロシン含有リガンド又はレセプターへのチロシンキナーゼ依存調節タンパク質の結合を抑制することができるホスホチロシン擬似物に関する。本発明はまた、ホスホチロシン擬似物を同定するための方法、キット及びその使用に関する。本発明の化合物、キット及び方法は、ＳＨ 2 結合ドメインを含有するシグナル形質導入タンパク質等のチロシンキナーゼ依存調節タンパク質のアンタゴニストの同定及び設計に有用である。
Patent JP-2001517224-A (JP)
Title: Ｎ−ピペリジノ−３−ピラゾールカルボキサミド誘導体、その塩およびそれらの溶媒和物の経口投与用医薬組成物
IPC: C07D231/14
Filed: 1998-03-27
Abstract: (57)【要約】
本発明は、微晶質形態にある０．５％から２０％のＮ−ピペリジノ−５−（４−クロロフェニル）−１−（２，４−ジクロロフェニル）−４−メチルピラゾール−３−カルボキサミドと、薬学的ベヒクルとを含有する経口投与のための医薬組成物に関する。該組成物は、湿式顆粒化により形成される。
Patent JP-2002502280-A (JP)
Title: ポリアミドを含むゴルフボール成形用組成物
IPC: A63B37/12
Filed: 1998-05-22
Abstract: (57)【要約】
コアおよびカバー、またはコアと中間層とカバーとを含むゴルフボールを特許請求する。該層の一つは、ポリアミドと非イオノマーとのブレンドを含む。好ましくは、該非イオノマーは、ポリエーテルエステル、ポリエーテルアミドまたは官能化SEBSである。
Patent MX-154811-A (MX)
Inventor: SENZAKI TAKASHI
IPC: C23C22/18
Filed: 1980-04-30
Abstract: An acidic aqueous coating solution containing from 0.4 to 1 g/l of zinc, from 5 to 40 g/l of phosphate, and from 0.01 to 0.2 g/l of nitrite. The solution is useful for forming on metal surfaces zinc phosphate coatings that exhibit excellent adhesion to a paint film and excellent corrosion resistance after painting when used as an undercoat for the cationic electrodeposition of a paint film.
Patent MX-158207-A (MX)
Inventor: BADERTSCHER ERNEST
IPC: B01J2/16
Filed: 1982-12-26
Abstract: An agglomeration nozzle with an axial passage for the product and an annular duct coaxial with the passage. An annular distribution chamber coaxial with the duct and passage supplies the agglomeration fluid to the duct. A first heating chamber surrounds the distribution chamber and a second heating chamber is disposed below the distribution chamber adjacent the end of the duct. A heating fluid may be introduced into the heating chambers to maintain the distribution chamber and duct at an elevated temperature.
Patent NZ-194528-A (NZ)
Title: 4-phenoxypiperidines preparation and pharmaceutical compositions containing them
Inventor: EISKETTER K
IPC: C07D211/52
Filed: 1980-08-01
Abstract: 4-Phenoxypiperidines of the general formula I    <IMAGE>  (I) wherein R1 denotes a hydrogen atom, an alkyl group with 1 to 5 carbon atoms, an alkenyl group with 3 to 5 carbon atoms, a cycloalkylmethyl group with 3 to 7 carbon atoms in the cycloalkyl part or a phenylalkyl group with 1 to 3 carbon atoms in the alkyl part, R2 denotes a hydrogen atom, a nitro group, an amino group or an acylamino group and R3 denotes a phenyl group or a benzyl group, and their N-oxides and their acid-addition salts are new compounds. They have an antiptotic and analgesic action and are suitable for the treatment of depressions and painful conditions. Processes for the preparation of the new compounds are provided.
Patent NZ-197894-A (NZ)
Title: Vortex separator for sewage treatment;conical flow modifier in solids outlet
Inventor: SMISSON B
IPC: B04C5/103
Filed: 1981-07-30
Abstract: A separator, which may be used for separating putrescent solids from water in sewage, comprises a vortex chamber (2) having an inlet (for the sewage), a first (solids) outlet (6) and a second (water) outlet (8). Near the outlet (6) there is a flow modifying member (14) which induces a secondary flow in the vortex chamber (2). This secondary flow passes radially inwardly beneath the member (14), upwardly through a passage (18) and downwardly over the outer surface of the member (14). The member (14), if suitably shaped and dimensioned, improves the efficiency of the separator.
Patent NZ-209721-A (NZ)
Title: Packaging laminate:extruded plastic layer on stiffening layer
Inventor: ANDERSSON T
IPC: B32B27/32
Filed: 1984-10-01
Abstract: A packing laminate for the manufacture of packing containers for edible oil must have an oil-resistant inner layer which is not affected by the oil, even during prolonged storage periods. A packing laminate meeting this condition has an extruded inner layer of two types of plastics mixed with one another, namely LLDPE and LDPE.
Patent NZ-215220-A (NZ)
Title: Process for dissolving squid membranes using an extract of squid liver
Inventor: LEUBA J L
IPC: A23L17/50
Filed: 1986-02-19
Abstract: An extract of squid liver in a brine is prepared and the cleaned and eviscerated squid is immersed in the extract to dissolve the thin and resistant membrane situated between the flesh and the skin of the squid.
Patent NZ-236333-A (NZ)
Title: Process for dimerisation of transforming growth factor b (tgf b)-like protein, product and monomeric s-sulphonated tgf-b like protein
Inventor: CERLETTI NICO
IPC: C12N15/09
Filed: 1990-12-04
Abstract: The invention relates to a process for the production of biologically active, dimeric TGF- beta , to novel TGF- beta s and pharmaceutical compositions comprising it. TGF- beta produced by this process can be used in various therapeutic modalities.
Patent NZ-237461-A (NZ)
Title: 10-trihydroxybutyl-1,4,
Inventor: PLATZEK JOHANNES
IPC: A61K49/00
Filed: 1991-03-18
Abstract: 1,4,7,10-Tetraazacyclododecane-butyltriols of the general formula IA <IMAGE>  in which   R<1> independently of one another denotes hydrogen or a metal ion equivalent and   R<2> denotes a butyltriol radical, and their salts with organic or inorganic bases or amino acids are useful pharmaceutical agents.
Patent NZ-246467-A (NZ)
Title: Tissue plasminogen activator variants and their preparation and use
Inventor: BENNETT WILLIAM F
IPC: A61K38/00
Filed: 1992-12-14
Abstract: Tissue plasminogen activator (t-PA) variants with substitution of leucine for phenylalanine, histidine for arginine, serine for isoleucine and threonine for lysine at amino acid positions (274, 275, 276 and 277) respectively, of wild-type human t-PA are prepared. DNA sequences can be prepared that encode such variants, as well as expression vectors incorporating the DNA sequences, and host cells transformed with the expression vectors. The variants exhibit improved fibrin-specificity and can be used in a pharmaceutical preparation to treat a vascular disease or condition or to prevent fibrin deposition or adhesion formation or reformation in mammals.
Patent NZ-251818-A (NZ)
Title: Producing flavour-oil microcapsules by emulsifying the oil in water, coating the droplets with a polymer by coacervation, and cross-linking the polymer; use of said aqueous microcapsules for flavouring foods
Inventor: WAMPLER DANIEL J
IPC: A23L27/00
Filed: 1993-03-30
Abstract: Aqueous liquid flavor oil capsules are made by coacervation and used in a wide variety of flavoring foods such as deep fat frying, baking microwaving and extrusion applications.
Patent NZ-259636-A (NZ)
Title: Hybridomas which produce monoclonal antibodies specific for multiple sclerosis and their use in diagnostic assays
Inventor: KLINE ELLIS LEE
IPC: C12P21/08
Filed: 1993-12-17
Abstract: The present invention relates to the diagnosis of multiple sclerosis. More specifically, this invention relates to an assay for detecting antigen(s) associated with multiple sclerosis. The present invention also relates to the generation of hybridomas which produce monoclonal antibodies which are specific for the multiple sclerosis-associated antigens. The present invention's use is in diagnosing multiple sclerosis and in routine follow-up monitoring of multiple sclerosis patients as to disease progression or response to therapy.
Patent NZ-269717-A (NZ)
Title: Biocontrol composition; comprises an antagonistic microorganism and a sugar analogue
Inventor: WILSON CHARLES L
IPC: A01N63/32
Filed: 1994-07-26
Abstract: A biocontrol composition comprising an antagonistic microorganism and a sugar analog (2-deoxy-D-glucose) gives a level of control superior to that of either component when used alone and comparable to that of synthetic chemical fungicides. The antagonistic microorganism is an isolate of Candida saitoana and has resistance to the fungicidal activity of sugars and sugar analogs.
Patent NZ-277150-A (NZ)
Title: Brush cutter; details of blades attached to a rotatable centre disc
Inventor: ROSDAHL HANS
IPC: A01D34/73
Filed: 1994-11-30
Abstract: A cutting tool for use with a brush cutter, trimmer or like device (1) for cutting thicket, grass and like vegetation, wherein the device includes a rotary shaft (3) for receiving a cutting tool which includes a rotatable center disc (6) which can be fitted to the tool and which includes cutting blades (9) having a cutting edge (10) along the front side of the blade as seen in the direction of rotation, wherein each individual cutting blade (9) is bent down through a first angle (v) such that the rear edge of the cutting blade (9) will be located closer to the ground than the edge-provided front side (10) of the blade when the center disc is held parallel with the ground, so that as the centre disc (6) rotates air will be pressed down towards the ground and therewith causes the tool to hover or lift slightly above the ground surface.
Patent NZ-282588-A (NZ)
Title: Di- and tri-peptide derivatives with amine, aminoimino, amidine and guanidine terminal substituents; medicaments
Inventor: SMITH GERALD FLOYD
IPC: C07D401/00
Filed: 1995-03-03
Abstract: This invention relates to thrombin inhibiting compounds haveing the Formula I X-Y-NH-(CH2)r-G where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors, and thromboembolic disorder agents.
Patent NZ-286695-A (NZ)
Title: N-(hydroxyarylalkyl) amide and urea derivatives and pharmaceutical compositions
Inventor: LESIEUR DANIEL
IPC: A61P25/28
Filed: 1996-05-30
Abstract: Alkoxy aryl derivatives of formula (I), their enantiomers and diastereoisomers, and their salts, are new. R1 = 1-4C alkylene chain, opt. substd by alkyl, OH, alkoxycarbonyl or carboxyl; R2 = H or alkyl; R3 = a group R31 or R32; R31 = -C(=X)-(CH2)n-R5; R32 = -C(=X')-NH-(CH2)m-R6; n = 0-3; X = S or O; R5 = H, opt. substd alkyl, alkenyl, alkynyl, opt. substd cycloalkyl, or opt. substd dicycloalkylalkyl; X' = O or S; m = 0-3; R6 = H, opt. substd alkyl, alkenyl or alkynyl, or may also be opt. substd cycloalkyl or opt. substd dicycloalkylalkyl when X' = O; A = alkyl or A'; A' = substd. alkyl, alkenyl, or alkynyl; R = opt. substd. alkyl, alkenyl, alkynyl, opt. substd cycloalkyl, opt. substd cycloalkylalkyl, opt. substd aryl, opt. substd aralkyl, opt. substd diarylalkyl, cycloalkenyl or cycloalkenyl alkyl; Y with the benzo group to which it is attached = a group Y'; Y' = naphthalene, benzofuran, benzothiophene, or indole if A = A', or Y = naphthalene if A = alkyl; Y' may be partially hydrogenated; with the provisos that: substituents on alkyl are one or more halo, OH, or alkoxy; substits on cycloalkyl, cycloalkylalkyl and dicycloalkylalkyl are one or more of halo, OH, alkyl, alkoxy or oxo; substits on aryl, arylalkyl and diarylalkyl are one or more halo, OH, alkyl, haloalkyl, or alkoxy; alkyl, alkoxy, alkenyl and alkynyl = up to 6C; cycloalkyl and cycloalkenyl = 3-8C; and aryl = phenyl or naphthyl.
Patent NZ-309882-A (NZ)
Title: High energy permanent magnet rotor motor generator
Inventor: TAKAHASHI YOSHIAKI
IPC: H02P9/30
Filed: 1996-06-13
Abstract: There is provided a power-generating electric motor (1) which is very excellent in the energy efficiency and capable of taking out an electric energy for a prolonged period of time, which motor comprises a rotor (2) made of a permanent magnet; an armature (11) disposed coaxially with the rotor (2) with an air gap therebetween and comprising a suitable number of field cores (13) provided each with a field coil (12); and a brushless control circuit, characterized by   a high BHmax permanent magnet (8) disposed inside the base portion of each magnet pole (5) of the rotor (2) and an induction coil (15) for an electric power generation disposed adjacent each of the field coils (12) of the armature (11).   <IMAGE>
Patent NZ-326504-A (NZ)
Title: Manufacturing boards having a homogeneous decorative surface layer by simultaneously electron-beam curing varnish and glue
Inventor: KEDING BJORN
IPC: B05D7/24
Filed: 1997-01-15
Abstract: A board has a homogeneous, decorative surface layers which include electron-beam cured varnish, the surface layers including a foil which is glued to a carrier board, the glue being electron-beam cured.  The homogeneity of the surface layers is produced by simultaneously electron-beam curing of the glue and of the varnish.
Patent NZ-331469-A (NZ)
Title: A hand dryer and a method of disinfecting and deodorising the dryer and air emitted from it
Inventor: SCHEEPERS ROGER BASIL LAWSON
IPC: A47K10/48
Filed: 1997-12-15
Abstract: method of disinfecting a hand dryer (10), a stream of air emitted from the hand dryer (10) or both is described.  The method comprises dispensing, substantially continuously, vapourised disinfectant into or in close proximity to the dryer (10) so that an amount of the disinfectant circulates in an area around and within the dryer (10) and is entrained in the stream of air emitted from the dryer (10).  The disinfectant contains triethylene glycol.  A hand dryer (10) comprises a housing and a liquid or solid carrier (19) impregnate with a disinfectant containing triethylene glycol is positioned in or on the housing for disinfecting the dryer.  A stream of air is emitted from the dryer or both.
Patent NZ-334307-A (NZ)
Title: Compounds for treating diseases wherein inhibition of Fas-mediated apoptosis is indicated
Inventor: FEUERSTEIN GIORA ZEEV
IPC: A61K31/40
Filed: 1997-08-22
Abstract: The compounds of Formula (I) may be used in the manufacture of medicaments for inhibiting the expression of Fas, for treating autoimmune diseases and for inhibiting tumor growth and metastasis.  In formula (I);  R7-R13 are independently H or OH; and A is a moiety of Formula (II), wherein; R1 is hydrogen, lower alkanoyl of up to 6 carbon atoms or aroyl selected from benzoyl and naphthoy!; R2 is hydrogen, lower alkyl of up to 6 carbon atoms or arylalkyl selected from benzyl, phenylethyl and phenylpropyl; R3 is hydrogen or lower alkyl of up to 6 carbon atoms; R4 is hydrogen or lower alkyl of up to 6 carbon atoms, or when X is oxygen, R4 together with R5 can represent CH2O; X is a single bond, CH2, oxygen or sulfur; Ar is selected from phenyl, naphthyl, indanyl and tetrahydronaphthyl; R5 and R6 are individually selected from hydrogen, fluorine, chlorine, bromine, hydroxyl, lower alkyl of up to 6 carbon atoms, a CONH2 group, lower alkoxy of up to 6 carbon atoms, benzyloxy, lower alkylthio of up to 6 carbon atoms, lower alkysulphinyl of up to 6 carbon atoms and lower alkylsulphonyl of up to 6 carbon atoms; or R5 and R6 together represent methylenedioxy.  A preferred compound of the formula above is carvedilol (1-(carbazol-4-yloxy-3-[(2-(o-methoxyphenoxy)ethyl]amino]-2-propanol).
Patent NZ-335850-A (NZ)
Title: Absorbent composition comprising a mixture of an acidic or basic water-swellable, water-insoluble polymer and a basic or acidic material
Inventor: QIN JIAN
IPC: C08J3/075
Filed: 1997-11-25
Abstract: Disclosed is an absorbent composition comprising either an acidic or a basic material. Specifically, the absorbent composition comprises either an acidic water-swellable, water-insoluble polymer having a pKa between about 2 to about 12 or a basic water-swellable, water-insoluble polymer having a pKb between about 2 to about 12 and either a basic or an acidic second material. The absorbent composition has the ability to slowly absorb a large quantity of liquid, particularly while under an external pressure. The absorbent composition is useful in disposable absorbent products, such as those disposable absorbent products that are used to absorb bodily liquids.
Patent NZ-336374-A (NZ)
Title: A wheel and brake assembly
Inventor: WILSON ROBERT CHARLES
IPC: B60B33/02
Filed: 1998-01-02
Abstract: A combined wheel and brake assembly for shopping trolleys, etc. of the type where a stationary brake member is sandwiched between two freely rotating wheel discs (16, 17-the drawings show the assembly in end view). When the trolley enters a ramp escalator the discs (16, 17) fall between the escalator ribs (42, 46, 47) bringing the brake area (25) into contact with the escalator. The weight of the trolley forces apart the resilient ribs (40, 41) of the brake member which grip rib (42) of the escalator and prevent movement of the trolley.
Patent NZ-336431-A (NZ)
Title: A table consisting of a plurality of slats support by at least two legs with a threaded rod or bolt hidden from view
Inventor: CHRISTIE DAVID ANDREW
IPC: F16B5/02
Filed: 1999-06-24
Abstract: A table with a table top and leg members to support the table top includes three juxtaposed and parallel panel sections defining the table top. Each panel is positioned relative to an adjacent panel in a non- butting relationship to define two elongate regions for separation to the tabletop. The leg members are positioned with each region of separation in a spaced relationship and extend therefrom to each provide an end of the leg which is ground engageable. The table also includes a clamping means that extends laterally to the elongate regions of separation and through at least part of each of the parallel panels and provides a clamping force of the panels towards each other to clamp each of the leg members between adjacent panels within their respective regions of separation.
Patent NZ-501771-A (NZ)
Title: Method for producing calcium pyruvates by reaction with pyruvic acid of calcium salts of organic compounds
Inventor: PISCHEL IVO
IPC: A61P43/00
Filed: 1998-07-02
Abstract: The application relates to a method for producing calcium pyruvates, where calcium salts of organic acids or acid organic keto or hydroxy compounds are reacted with pyruvic acid at a temperature ranging from -20 to +120oC, optionally in the presence of a diluent or a solvent. This enables the production of highly pure calcium pyruvates which can be substantially water-free and exhibit very good storage stability. The calcium pyruvates are used to increase stamina and vigour in the field of sports, to reduce weight and fat, and as protective substance for body cells and tissues and as substance for inhibiting the formation of free radicals, as well as free radical scavenger in body cells and tissues in health care and as food additive.
Patent NZ-502839-A (NZ)
Title: Lipid-containing compositions and uses thereof
Inventor: TONGE STEPHEN RONALD
IPC: A61K9/127
Filed: 1998-08-24
Abstract: A lipid-containing liquid composition comprising a membrane-forming polar lipid dispersed in an aqueous medium together with a synthetic amphipathic polymer that interacts with the polar lipid to produce a polymer/lipid complex.  The polymer interacts with and solubilizes the polar lipid in the aqueous medium at a pH that is below a critical lipid-solubilizing value and at a temperature above a predetermined phase transition temperature dependant upon the polar lipid.  The composition is pH variable, such that the pH can be raised from below the critical lipid-solubilizing value to above the critical lipid-solubilizing value by addition of alkaline reagent.
Patent NZ-508626-A (NZ)
Title: Method and system of ranking participants in a betting competition
Inventor: CASSIDY GARTH MCMILLAN
IPC: G07F17/32
Filed: 2000-12-04
Abstract: A method of ranking participants in a competition comprises: a) presenting to a participant data representing one or more sporting events with each sporting event involving two or more individuals or teams; b) obtaining from a participant a predicted score for each team for each sporting event; c) storing the predicted scores in a data memory; d) assigning a maximum numerical rating to each participant; e) obtaining actual scores for each team for each sporting event; f) storing the actual scores in a data memory; g) retrieving one or more predicted scores and one or more actual scores for each participant h) comparing the retrieved predicted scores with the retrieved actual scores for each participant and i) reducing the maximum rating for each participant by a penalty based on differences between the retrieved predicted scores for the participants and the retrieved actual scores. A system for ranking participants in a competition comprises: j) a display arranged to present to a participant data representing one or more sporting events with each sporting event involving two or more individuals or teams; k) a data entry component arranged to obtain from a participant a predicted score for each team for each sporting event and to store the predicted scores in a data memory; l) a rating assignor arranged to assign a maximum numerical rating to each participant; m) a data entry component arranged to obtain actual scores for each team for each sporting event and to store the actual scores in a data memory; n) a comparator arranged to retrieve one or more predicted scores and one or more actual scores for each participant and to compare the retrieved predicted scores with the retrieved actual scores for each participant and i) a rating assignor arranged to reduce the maximum rating for each participant by a penalty based on differences between the retrieved predicted scores for the participants and the retrieved actual scores.
Patent NZ-509582-A (NZ)
Title: Process for obtaining HMG-CoA reductase inhibitors of high purity using displacement chromatography
Inventor: MILIVOJEVIC DUSAN
IPC: A61K31/22
Filed: 1999-09-17
Abstract: A process for purifying a crude HMG-CoA reductase inhibitor by displacement chromatography comprises: a) conditioning a chromatography column having a stationery phase with mobile phase; b) feeding the HMG-CoA reductase inhibitor dissolved in the mobile phase onto the chromatography column; c) introducing the displacer for displacing the HMG-CoA reductase inhibitor from the column and d) obtaining the purified HMG-CoA reductase inhibitor.
Patent NZ-512947-A (NZ)
Title: Griddle plate with infrared heating element
Inventor: REAY MALCOLM
IPC: H05B3/72
Filed: 2000-01-24
Abstract: A cooking appliance (10) for grilling food products has a griddle plate (11) and a heating assembly (20) that contains a non-contact infrared heating element (30) to achieve uniform plate temperatures, fast initial warming times and fast recovery times. The heating element is situated in a cavity (29) formed by thermal insulating material (27) in the assembly. When the assembly (20) is secured to the griddle plate (11), there is a space (29) between the heater element (30) and the griddle plate (11) to allow infrared radiation heat transfer to heat the griddle plate. The insulating material has a relatively high insulating factor so as to minimize heat loss and reduce energy usage.