Patent EP-2382865-A1 (EP)
Inventor: BRETSCHNEIDER THOMAS DR
IPC: A01P7/04
Filed: 2010-11-09
Abstract: Active agent combination comprises: at least one substituted pyridine compound (I) and their salts, metal complexes and N-oxides; and one or more active agents comprising e.g. acetylcholinesterase inhibitors (carbamate (e.g. alanycarb, aldicarb and aldoxycarb), organophosphate (e.g. acephate, azamethiphos, azinphos (-methyl, -ethyl) and bromophosethyl)) and gamma -aminobutyric acid-gated chloride channel antagonists (organochlorine (e.g. camphechlor, chlordane and endosulfan), fiprole (e.g. acetoprole, ethiprole, fipronil and pyrafluprole) and vaniliprole). Active agent combination comprises: at least one substituted pyridine compound of formula (I) and their salts, metal complexes and N-oxides; and one or more active agents comprising e.g. acetylcholinesterase inhibitors (carbamate (e.g. alanycarb, aldicarb and aldoxycarb), organophosphate (e.g. acephate, azamethiphos, azinphos (-methyl, -ethyl) and bromophosethyl)), gamma -aminobutyric acid-gated chloride channel antagonists (organochlorine (e.g. camphechlor, chlordane and endosulfan), fiprole (e.g. acetoprole, ethiprole, fipronil and pyrafluprole) and vaniliprole), sodium channel modulators/voltage-dependent sodium channel blocker (pyrethroid (e.g. acrinathrin, allethrin and beta -cyfluthrin)), nicotinergic acetylcholine receptor agonist/antagonist (chloronicotinyl (e.g. acetamiprid, clothianidin and dinotefuran), nicotine, bensultap, cartap or thiosulfap-sodium), spinosyn (e.g. spinosad and spinetoram), juvenile hormone analogs (e.g. hydroprene and kinoprene), fumigant (e.g. methyl bromide and chloropicrin), selective antifeedants (e.g. cryolite and pymetrozine), mite growth inhibitors (e.g. clofentezine and hexythiazox), inhibitors of oxidative phosphorylation, ATP disruptors (diafenthiuron, organo tin compounds (e.g. azocyclotin and cyhexatin), propargite and tetradifon), and drugs with unknown mechanism of action (e.g. amidoflumet, benclothiaz, benzoximate, bromopropylate, buprofezin, chinomethionat, chlordimeform, chlorobenzilate, clothiazoben cycloprene, dicofol, dicyclanil, fenoxacrim, fentrifanil, flubenzimine, fluensulfone (5-chloro-2-[(3,4,4-trifluorobut-3-en-1-yl)sulfonyl]-1,3-thiazole), flufenerim, flutenzin, potassium oleate, pyridalyl, sulfluramid, tetrasul, triarathene and verbutin). Either G1 : N, CH or C-halo; and G2 : thiazolyl group of formula (a); and G3 : heterocyclyl or (hetero)aryl (both optionally substituted); and R1 : H or alkyl; or G1 : N or C-halo; and G2 : thiadiazolyl group of formula (b); and G3 : heterocyclyl or (hetero)aryl (both optionally substituted); or G1 : CH; and G2 : (b); and G3 : optionally substituted heterocyclyl, substituted furanyl or thienyl (substituted by halo, nitro, amino, alkylamino, dialkylamino, haloalkyl, cycloalkylalkyl, (halo)alkoxy, alkylthio, alkoxyalkyl, bis(alkoxy)alkyl, alkoxycarbonyl, alpha -hydroxyimino-alkoxycarbonylmethyl, alpha -alkoxyimino-alkoxycarbonylmethyl, C(X)NR2R3, alkylsulfinyl, alkylsulfonyl, heterocyclyl, aryl (optionally substituted by halo, cyano, nitro or (halo)alkyl), heteroaryl (optionally substituted by halo, nitro, (halo)alkyl, (halo)alkoxy, alkoxyalkyl, alkylthio, alkylthioalkyl or cycloalkyl) or heteroarylalkyl (optionally substituted by halo, nitro, (halo)alkyl, (halo)alkoxy, alkoxyalkyl, alkylthio, alkylthioalkyl or cycloalkyl)), optionally substituted heteroaryl comprising pyrrolyl, pyrazolyl, imidazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, 1,2,3-oxadiazolyl, 1,2,4-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2,5-oxadiazolyl, 1,2,3-thiadiazolyl, 1,2,4-thiadiazolyl, 1,3,4-thiadiazolyl, 1,2,5-thiadiazolyl, pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, 1,2,3-triazinyl, 1,2,4-triazinyl, 1,3,5-triazinyl, benzofuryl, benzisofuryl, benzothienyl, benzisothienyl, indolyl, isoindolyl, indazolyl, benzothiazolyl, benzisothiazolyl, benzoxazolyl, benzisoxazolyl, benzimidazolyl, 1,2,3-benzoxadiazolyl, quinolinyl, isoquinolinyl, cinnolinyl, phthalazinyl, quinazolinyl, quinoxalinyl, naphthyridinyl, benzotriazinyl, purinyl, pteridinyl or indolizinyl, or aryl (substituted by cyano, nitro, haloalkoxy or heterocyclyl); and either R2 : H or alkyl; or R3 : (halo)alkyl, alkoxy, cyanoalkyl, alkynyl, cycloalkyl, cycloalkylalkyl, alkoxyalkyl, alkylthioalkyl or arylalkyl; or R2NR3 : a ring; and X : O or S; or G1 : N, CH or C-halo; and G2 : pyrazolyl group of formula (c); and R1 : H or alkyl; and G3 : heterocyclyl or (hetero)aryl (both optionally substituted). [Image] ACTIVITY : Insecticide; Acaricide; Fungicide; Antibacterial; Virucide. The insecticidal activity of the combination (comprising 2-[6-(2-pyridin-3-yl-thiazol-5-yl)-pyridin-2-yl]-pyrimidine (4 g/hectare) and thiamethoxam (0.16 g/hectare) in a ratio of 25:1) against Myzus persicaewas tested in Brassica oleraceaor wild cabbage. The results showed that the combination exhibited an efficiency of 80% after 1 day. MECHANISM OF ACTION : None given.