baber/WOPTO huggingface dataset:
Patent PT-626844-E (PT)
Inventor: BAROODY LLOYD J
IPC: A61K31/12
Filed: 1993-01-15
Abstract: Compositions suitable for the treatment of acne by topical application comprise clindamycin and benzoyl peroxide. Kits for preparing the compositions include a solution of clindamycin in a first container and a gel suspension of benzoyl peroxide in a second container. Each component is stored at a pH which promotes stabiliy and the combination of the two components provides a final compositioin having a pH which promotes stability and enhances viscosity.
Patent PT-649414-E (PT)
Inventor: BUBACZ DULCE GARRIDO
IPC: A61K38/05
Filed: 1993-02-02
Abstract: PCT No. PCT/GB93/00216 Sec. 371 Date Aug. 3, 1994 Sec. 102(e) Date Aug. 3, 1994 PCT Filed Feb. 2, 1993 PCT Pub. No. WO93/15062 PCT Pub. Date Aug. 5, 1993Diarylmethylpiperazine compounds having utility as receptor-binding species, e.g., for mediating analgesia, and for combatting drug addiction, alcohol addiction, and drug overdose. The compounds may be administered orally, rectally, topically, nasally, ophthalmically, or parenterally (subcutaneously, intramuscularly, and intravenously), for veterinary and human use, and include delta receptor and mu receptor binding species.
Patent PT-659883-E (PT)
Inventor: TAJIMA HISAO
IPC: C12N1/21
Filed: 1994-11-24
Abstract: The present invention is related to a novel protein p140 polypeptide which is a key protein involved in the signal transmission system of insulin; method for preparation of it; DNA encoding the said polypeptide; vector derived the said DNA; host cells transformed the said vector; antibody of the said polypeptide; pharmaceutical composition containing the said peptide or antibody; method for the prevention and/or treatment of diabetes, which is characterized by tyrosine phosphorylation of the said protein p140; agent for the prevention and/or treatment for the currently said the prevention and/or treatment method; agent for the prevention and/or treatment of diabetes, which is characterized by containing a compound which can tyrosine phosphorylation of protein p140, as active ingredient and the screening methods of the said prevention and/or treatment agent. Tyrosine phosphorylation of protein p140 is an essential step in the induction of hypoglycemia by glucose uptake. Method and agent of prevention and/or treatment based on tyrosine phosphorylation of protein p140 in the present invention is not only improve the diabetes-derived hyperglycemic conditions but are also useful for the treatment and/or prevention of diabetes, especially non-insulin dependent diabetes mellitus (NIDDM).
Patent PT-725790-E (PT)
Inventor: HUPE DONALD
IPC: A61K38/55
Filed: 1994-10-21
Abstract: Inhibitors of protein: farnesyl transferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.
Patent PT-712618-E (PT)
Inventor: YOON HEE K
IPC: A61B19/04
Filed: 1995-11-17
Abstract: The present invention relates to lubricous gloves for applying orthopaedic casting bandages of the type used to form orthopaedic casts. In particular, the invention relates to a coated glove having a lubricous coating which is flexible to resist cracking while assisting in the application of orthopaedic bandages of the type having an uncured resin coating thereon.
Patent PT-781896-E (PT)
Inventor: TROJAHN WERNER
IPC: F01D15/06
Filed: 1996-12-23
Abstract: The turbine wheel has a disc wheel body (1) with a central bearing mounting opening (2) with concentric inlet openings (3) at the periphery on one disc side (3), and driving air channels (5) from the disc body each opening into an outlet (14). The outlet openings (14) are at the peripheral surface (7) of the wheel disc. The drive air channels have an axial inflow section (6) and an outflow section (8) in the wheel disc body towards the circumference surface.
Patent PT-773020-E (PT)
Inventor: CAVAZZA CLAUDIO
IPC: A61K31/22
Filed: 1996-10-11
Abstract: The co-ordinated therapeutic use of L-carnitine, lower alkanoyl L-carnitines or the pharmacologically acceptable salts thereof with resveratrol, resveratrol derivatives or resveratrol-containing natural products is disclosed for producing a medicament for the prophylaxis and treatment of cardiovascular disorders, peripheral vascular diseases and peripheral diabetic neuropathy.
Patent PT-830604-E (PT)
Inventor: NOTEBORN MATHEUS HUBERTUS MARI
IPC: G01N33/574
Filed: 1996-06-07
Abstract: This invention describes that apoptin fails to induce apoptosis in human normal cells. Besides, the invention describes that when normal cells are transformed, they become susceptible to the apoptin-induced apoptosis. The invention describes that apoptin induces in various human tumor cells a p53-distinct type of apoptosis, and cannot be blocked by a variety of apoptosis-inhibiting agents. The invention comprises an anti-tumor agent, which specifically kill tumor and not normal cells. It further provides the induction of cell death by means of gene therapy. Apoptin can induce apoptosis in non-human animal tumor cells. The invention also provides that in normal cells apoptin was found predominantly in the cytoplasm, while in tumor cells it was located in the nucleus. Besides, the invention comprises a diagnostic test for the determination of cell-transforming activity.
Patent PT-882707-E (PT)
Inventor: MIYOSHI SHIRO
IPC: C07C311/08
Filed: 1996-12-18
Abstract: Compounds represented by general formula (I) or salts thereof, a process for producing the same, and intermediates therefor, wherein R represents hydrogen or methyl; R<1> represents hydrogen, hologeno, hydroxy, benzyloxy, amino, or hydroxymethyl; R<2> represents hydrogen, hydroxymethyl, NHR<3>, SO2NR<4>R<4>, or nitro; R<6> represents hydrogen or lower alkyl; and X represents nitrogen, oxygen, sulfur, or methylene, provided that when X represents nitrogen, oxygen, or sulfur, then R<9> represents hydrogen, one of R<7> an R<8> represents hydrogen, and the other thereof represents hydrogen, amino, acetylamino, or hydroxy, and when X represents methylene, then R<7> and R<8> each represents hydrogen and R<9> represents hydrogen, amino, etc. They have a  beta -3 adrenaline receptor agonist and are useful as drugs for the treatment and prevention of diabetes, obesity, hyperlipemia, etc. <CHEM>
Patent PT-821952-E (PT)
Inventor: MULLNER STEFAN
IPC: A61K31/44
Filed: 1997-07-28
Abstract: Use of compounds of formula (I) or (II) and their salts is claimed for the modulation of apoptosis. R1 = 1-4C alkyl, 3-5C cycloalkyl, 2-6C alkenyl or 2-6C alkynyl; R2 = CF3, OCF3, SCF3, OH, NO2, halo, benzyl, phenyl, CN or phenoxy (optionally substituted by 1-4C alkyl, halo, OCF3 or OCH3); R3 = 1-4C alkyl, halo or H; and X = CH or N.
Patent PT-848855-E (PT)
Inventor: SASSMANNSHAUSEN GUNTER
IPC: H01M50/443
Filed: 1997-04-22
Abstract: The invention relates to a method of treating elastic material that is provided with silica embedments to avoid shrinkage, whereby the finished material that is provided with the silica embedments is subjected for a prescribed period of time to temperatures above 40° C. prior to further processing.
Patent PT-919961-E (PT)
Inventor: HOEPPNER HARALD
IPC: B42D15/10
Filed: 1998-08-31
Abstract: The security element has a vol. hologram into which the kinetic effect is introduced. The hologram (2) is produced using two or more different wavelengths. It can be made from a surface relief by optical copying Independent claims are also included for a document with a security element and a method of manufacturing a document
Patent PT-906832-E (PT)
Inventor: RAINER GUMBIOWSKI DR
IPC: D06Q1/12
Filed: 1998-10-01
Abstract: An organic pigment with a specific surface area greater than 1 m<2>/g is used in the receptive layer of a printable substrate, comprising a base and receptive layer, for thermal transfer printing onto flat porous surfaces.
Patent PT-1144137-E (PT)
Inventor: WERDINIG HELMUT
IPC: B07B1/18
Filed: 1999-05-17
Abstract: The screening device uses a rod (8) which is wound into a spiral (10). It is rotated is fed into the interior of the spiral, e.g. via a rotary feed drum (2) with the spiral attached to it at one end. The rotary feed drum may be inclined to the horizontal, with the spiral attached to its lower end. The axis of the spiral may be curved downwards due to the spiral weight.
Patent PT-1101090-E (PT)
Inventor: HEUFT BERNHARD
IPC: B07C5/34
Filed: 1999-07-29
Abstract: To test the tightness and/or the correct closure of containers which are transported on a conveyor, the containers succeeding each other at brief time intervals and the containers being sealed by attachment of a closure, a characteristic dependent on the internal pressure (internal-pressure characteristic) of the container is measured. Upon attachment of the closures to the containers, the internal-pressure characteristic or parameters of the closures or containers, knowledge which is necessary to measure the characteristic depending on the internal pressure, are recorded. The containers are marked no later than when the closure is attached in a way which permits the values recorded upon attachment of the closures to be allocated to the respective container. The internal pressure of the container is ascertained from the value, measured at a time interval after the attachment of the closure, of the internal-pressure characteristic, and comparison with the value of the internal-pressure characteristic measured upon attachment of the closure or taking account of the parameters recorded. In the case of rigid containers such as glass bottles, the internal-pressure characteristic is typically the oscillation frequency of the closures; in the case of flexible containers such as PET bottles, on the other hand, it is the fill level. The marking can consist of a magnetization of the closure.
Patent PT-1144543-E (PT)
Inventor: KATHIRGAMANATHAN POOPATHY
IPC: H01L51/50
Filed: 1999-12-01
Abstract: Lithium quinolate is an electroluminescent material which emits light in the blue region of the spectrum.
Patent CA-2425162-F (CA)
Title: Air bed with elevated and self-expanding support structure
Inventor: CHOI HARRISON
IPC: A47C17/64
Filed: 2001-07-17
Granted: 2002-04-11
Abstract: A collapsible bed (10) having an air mattress (14) and a support frame (18).  The support frame (18) includes a number of frame members (2), which are joined by pivot assemblies (36), such that the support frame (18) as a whole expands outwardly from a central area (42), when a portion of the frame (18) is pulled outwardly. A second preferred embodiment is a self-expanding bed (100) having an air mattress (14) and an articulated support frame (18), which as a whole expands outwardly from a central area (42). The air mattress (14) is attached to the support frame (18) at a number of points, so that when the air mattress (14) is inflated and expands outwardly, the support frame (18) also expands outwardly. An electric air pump (60) is preferably included which may be activated by a remote control (64), so that the bed (100) is self-expanding.
Patent SG-70184-G (SG)
Title: Production of high surface area carbon blacks
IPC: C09C1/50
Filed: 1984-10-01
Abstract: This disclosure relates to an improved furnace process for producing carbon blacks by the incomplete combustion of hydrocarbonaceous feedstock wherein the resultant blacks have higher surface areas than the carbon blacks normally prepared from the feedstocks, as a result of which the blacks are particularly suitable for use in imparting conductivity properites to plastic materials and the like. This disclosure also relates to the production of a novel class of furnace blacks having excellent conductivity properites and which are characterized by high surface areas and low pH values.
Patent IE-810136-L (IE)
Title: Yarn texturing jet
IPC: D02G1/16
Filed: 1981-01-26
Abstract: A self-stringing jet device which is compact and easy to string up includes a body, a yarn inlet section, and a movable venturi and a rotatable cylindrical baffle located at the outlet end of the jet. The yarn inlet section comprises a cone-shaped yarn entrance having an axis that is at an angle with the axis of the yarn passage through the jet. The venturi may be moved from a stringup position to an operating position by one or more camming surfaces on the rotatable cylindrical baffle.
[US4259768A]
Patent IE-38689-L (IE)
Title: Urea-based feedstuffs.
IPC: A23K50/15
Filed: 1973-04-30
Abstract: 1376549 NPN feed PIERREFITTE-AUBY and COMPAGNIE FRANCAISE DE L'AZOTE 2 May 1973 [3 May 1972] 20868/73 Heading A2B An animal feedstuff comprising urea, a material comprising starch and a cellulosic product, the urea dissolving from the mixture relatively slowly in an aqueous medium, is prepared by subjecting an intimate mixture of small particles of urea and the other components to pressure in the absence of added water, and preferably without external heat, for example in a granulating press. The starchy material may be a cereal flour or a maize product, and the cellulosic product may be for example algae or alfalfa meal, oil bean cake, or sunflower husks. Granulation may be facilitated by additives such as refatted maize or tallow powder.
[GB1376549A]
Patent IE-39193-L (IE)
Title: Heterocyclic substituted piperazines.
IPC: C07D307/79
Filed: 1974-03-29
Abstract: Disubstituted piperazines of the formula: (From US3944551 A) [GB1407552A]
Patent IE-32356-L (IE)
Title: Registering apparatus
IPC: G06C15/02
Filed: 1968-07-19
Abstract: 1,232,420. Coding and decoding. SCM CORP. 19 July, 1968 [21 July, 1967], No. 34631/68. Heading H4P. An electro-mechanical register in which numerical information is fed manually or automatically from say a punched tape or a computer, comprises a keyboard, Fig. 18 (not shown), which operates a combination of switches (1, 2, 4, 8) energizing a corresponding number of solenoids which determine the angular rotation in turn of a set of gears acting as a store, which rotation is transferred to print wheels for parallel visual read out. Energization of one or more solenoids 1, 2 &c., Fig. 17, on partial depression of any key moves a corresponding number of stops, e.g. 172, out of the path of sidewardly movable pins 152 of a friction driven paddle wheel 151 which advances a corresponding number of pins when a " go " solenoid 209 is energized on full depression of a key. On release of the solenoid(s) the pins are returned to the inoperative, i.e., left-hand position. Paddle wheel movement is transmitted through gears to an input gear 105 meshing in turn with each of storage gears 37 which are held from rotation in other than the meshing position by a spline on elements 106, 107. Depression of a print key (500) energizes a solenoid (66) which moves the gears into engagement with racks 13, Fig. 1, and also a solenoid (66A) which engages a machine clutch causing a forward, i.e., left-hand movement of the racks which each advance to a position corresponding to the remainder of the travel of the gears 37 to the zero position and hence print wheels 12 are also rotated correspondingly. Solenoids (66, 66A) are held energized for half a machine cycle by a cam-operated switch (560). The printing mechanism may be of known type and on completion of the left-hand movement of racks 13, a paper tape is brought against the type wheels. Subsequently the wheels are restored in zero position on spring return of the racks to their home position. Information may be entered through a remote keyboard or a local or remote punched tape, and machines may be run in parallel. Electrical signals from the switches may be transmitted to a computer also the printer may be controlled from such computer.
[GB1232420A]
Patent IE-38690-L (IE)
Title: Producing diphenylamines
IPC: B01J21/00
Filed: 1973-06-06
Abstract: 1426929 Diphenylamines SNAMPROGETTI SpA 12 June 1973 [24 June 1972] 27972/73 Heading C2C A process for producing diphenylamine or a derivative thereof comprises reacting an imine having the formula wherein each of R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP>, R<SP>4</SP> and R<SP>5</SP>, which can be the same or different, is a hydrogen or halogen atom or alkyl, phenyl, amino, alkoxy or hydroxy group with oxygen or a gaseous mixture including oxygen, at a temperature in the range 300 to 450 C. Catalysts may be employed, active silica being preferred. Examples describe the preparation of 4-chloro-, 4-methoxy- and 4-methyldiphenylamines and diphenylamine.
[GB1426929A]
Patent IE-900942-L (IE)
Title: Circuit for detecting a frequency reference signal
IPC: H04B7/26
Filed: 1990-03-15
Abstract: The invention relates to a circuit for recognising a reference frequency signal which is transmitted with a data signal in time- division multiplex mode. A circuit of this type is provided for mobile radio systems in order to correct the frequency standard of the mobile stations through transmission of a reference frequency from the (fixed) base stations. In order to ascertain the temporal position of a reference frequency signal of this type, a solution is to be described in the implementation of which expensive circuits and high processing speeds are avoided. The invention provides a circuit with two transverse filters (1) which serve to distinguish between the data signal and the FC burst (frequency correction burst). They are designed so that the transmission factor of one filter shows a minimum at the FC frequency, while that of the other shows a maximum at that frequency. A device (2, 3) to determine the absolute value of the filter output signals, an arrangement (4 to 9) to form the sliding mean value over the period of a burst length and a device (10) to form the quotient of the output voltages of both paths are in each case connected downstream from the transverse filters (1). <IMAGE>
Patent FI-820453-L (FI)
Inventor: SHANTON KENNETH JOHN
IPC: B41M5/155
Filed: 1982-02-11
Abstract: A colour developer for use in a pressure- or heatsensitive record material comprises a particulate amorphous hydrated silica/hydrated alumina composite in which the hydrated silica and hydrated alumina are chemically bound, in which hydrated silica predominates, in which the mean alumina content on a dried weight basis is at least 7.5%, based on the total weight of silica and alumina, and in which the surface area is below 300m<2>g<-><1>. The composite may be metal-modified.
Patent FI-852792-L (FI)
Inventor: GALER RICHARD EUGENE
IPC: C04B7/02
Filed: 1985-07-16
Abstract: An ettringite-producing hydraulic cement especially adapted to the high speed production of carbon dioxide resistant cement board produces essentially all of its potential ettringite within about 20 minutes after it is mixed with water. The cement is non-expansive and sets within about 25 minutes at a temperature of from about 65°F to about 150°F.
Patent IE-901051-L (IE)
Title: Use of indole derivatives as pharmaceuticals
IPC: A61K31/415
Filed: 1990-03-21
Abstract: Described is the use of 5-chloro-1-(4-fluorophenyl)-3-(1-(2-(2-imidazolidinon-1-yl)ethyl)-4-pi peridyl)-1H-indole , or a pharmaceutically acceptable acid addition salt thereof, for the manufacturing of a pharmaceutical composition selectively blocking dopamine neurones in the ventral tegmental area in the brain, substantially without inhibiting the activity of dopamine neurones in substantia nigra pars compacta.
Patent IE-34660-L (IE)
Title: Switch-circuit breaker device
IPC: H01H1/029
Filed: 1970-09-14
Abstract: 1290963 Electric connectors ESSEX INTERNATIONAL Inc 15 Sept 1970 [15 Sept 1969] 44036/70 Heading H2E [Also in Division H1] An electrical connector, Fig. 7, comprises a resilient deformable pad 2e of insulating material, e.g. silicone rubber loaded with a plurality of metal particles, e.g. spheres of Ag or Ag coated Cu. An insulating casing comprising two halves 34, 35, each half having a plurality of conductors 36 with heads 37 projecting within the casing, encloses pad 2e when the halves are latched together as shown, the pad 2e between opposing heads 37 producing conductive paths between such heads. In Fig. 6, similar pads are attached at the forward ends of sprayed-on conductors 30 on a tubular plug 29; when the plug is mated with a socket 31, the pads 2d are compressed by socket contacts 33 to become conductive. A band of pad material spanning all conductors 30 may replace discrete pads 2d. In a circuit board (Figs. 14, 15 not shown) a pad (2i) is compressed between two insulating plates (78, 79) one (78) of which is provided on its inner surface with upstanding ribs (82) which define a conductive pattern. In Fig. 20, wires 103 are electrically connected to wiring 102 on a printed circuit board 101, a pad 2l being compressed, by means of clamped-together insulating bars 104, between wires 103 and wiring 102.
[GB1290963A]
Patent IE-901242-L (IE)
Title: Heteroarylmethoxy phenylalkanol derivatives
IPC: C07C69/007
Filed: 1990-04-06
Abstract: Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds which, by inhibiting 5-lipoxygenase enzyme and/or blocking leukotriene receptors, are useful in the prevention or treatment of asthma, arthritis, psoriasis, ulcers, myocardial infarction, stroke and related disease states in mammals; pharmaceutical compositions thereof; and a method of treatment therewith.
Patent IE-791274-L (IE)
Title: Plant fraction
IPC: A61P17/00
Filed: 1979-08-08
Abstract: Fractions extracted from the rhyzomes or leaves of various ferns, in particular Dryopteris crassirhizoma, Polypodium vulgare, Linn, Polypodium leucotomos, Phelbodium Decumanun J. Smith, Polypodium decumanun, Cyathea taiwaniana, or rhyzomes of Polypodium aureum Linn or Polypodium triseriales, are effective in treatment of psoriasis. The fraction is extracted in a polar solvent by partitioning an extract between a polar solvent and a non-polar solvent e.g. water and n-hexane. Further purification of the fraction may occur e.g. by passing through an interchange column, neutralising with calcium hydroxide and recrystallising.
[GB2024622A]
Patent IE-791540-L (IE)
Title: Spiro-furanohydantoin derivatives
IPC: A61P13/02
Filed: 1979-08-10
Abstract: {PG,1 Novel spiro-furanohydantoin derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. The compounds include 2-methyl-spiro-{8 cyclohexa(b)furan-4,4{40 -imidazolidine{9 -2{40 ,5{40 -dione, 2-fluoro-spiro-{8 cyclohexa(b)furan-4,4{40 -imidazolidine{9 -2{40 ,5{40 -dione, 2-chloro-spiro-{8 cyclohexa(b)furan-4,4{40 -imidazolidine{9 -2{40 ,5{40 -dione, 2-bromo-spiro-{8 cyclohexa(b)furan-4,4{40 -imidazolidine{9 -2{40 ,5{40 -dione and spiro-{8 cyclohexa(b)furan-4,4{40 -imidazolidine{9 -2{40 ,5{40 -dione.
[US4147797A]
Patent IE-901683-L (IE)
Title: Compounds
IPC: A61P43/00
Filed: 1990-05-09
Abstract: Compounds of structure <CHEM> in which R<1> is hydroxy, hydroxyC1-4alkyl, hydroxyC1-4alkoxy, carboxyC1-4alkoxy, C1-4alkoxyC1-4alkoxy, O(CH2)mHet, C1-4alkylNR<6>R<7> or O(CH2)mNR<6>R<7> in which m is 2 to 4 and R<6> and R<7> are the same or different and are each hydrogen, C1-4alkyl, Het, or -(CH2)nAr where n is 0 to 4, Ar is an optionally substituted phenyl ring, m is 2 to 4 and Het is an optionally substituted heterocyclic ring, or R<6> and R<7> together with the nitrogen to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms; R<2> and R<3> and R<4> and R<5> are the same, or different and, are each hydrogen, C1-4alkyl, -(CH2)nAr in which n is 0 to 4 and Ar is an optionally substituted phenyl ring, or R<2> and R<3> together with the nitrogen atom to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms process for their preparation, pharmaceutical compositions containing them and their use in therapy as inhibitors of gastric acid secretion.
[EP0404322A1]