baber/WOPTO huggingface dataset:
Patent CA-2113157-C (CA)
Inventor: ELVEGAARD EILIF
IPC: F16L3/12
Filed: 1992-07-10
Granted: 2002-07-09
Abstract: A clamping device for the clamp-ing of one or more tubes or the like to a support, comprising a base member (1) having at least one recess (2) for receiv-ing a tube (4) or the like, a top plate (11) for bearing against the base member (1) at the side facing away from the support (6), and at least one fastening screw (7; 8) extending through aligned holes (12, 9; 13, 10) in the top plate (11) and the base member (1), for attachment to the support (6). Each fastening screw (7; 8) is a screw bolt holding said elements (1, 11) together as a completely preassem-bled, mounting-ready unit without loose elements, the screw at the end to be fastened to the support (6) having a head (14; 15) arranged to be passed through an adapted hole (16; 17) or slot in the support (6), and to be locked in relation to the support by tightening of a nut (18; 19) at the other end. The recess (2) is outwardly open and at its opening (3) is formed with a narrowed portion for gripping and securing an inserted tube (4), and the opening (3) faces either the support (6) or the top plate (11), the top plate in the latter case being formed so as to be pivotable about said fastening screw, to be able to expose the opening.
Patent CA-2114311-C (CA)
Title: Monoclonal wb b-cell line
Inventor: WEE RICHARD KIAN-HOCK
IPC: C12N5/0781
Filed: 1991-11-25
Granted: 1996-02-27
Abstract: A human B-cell line (designated WB) was selectively cloned from peripheral blood of a healthy 48 year-old Chinese male by use of a serum-free defined medium. The in vivo pre-activated B-cells required an 8-week "incubation period" before large clusters of cells with apical cytoplasmic projections directed radially outwards became apparent, and their gradual proliferation was observed. Within a week, sufficient cell clusters predominate  to allow a 1:2 split twice weekly. Phase-contrast microscopy showed individual cells as 10u  to 20u  fusiforms  with  abundant  phase-dense granules.  By electron microscopy, each  cell revealed numerous inclusion bodies, mitochondria,  stratified rough endoplasmic reticulum (RER), carbohydrate inclusions, and a heterochromatic thick-rimmed, irregular large nucleus containing a prominent  nucleolus. These EBV-negative WB cells expressed the CD19 and CD20 pan-B antigens,  IgG, and activation markers DR, DQ, Leu 8, CD23,  CD25, CD38, and CD71. After 6 months of subculture, the cell line was adapted to culture in a protein-free RPMI 1640 medium. Interestingly,  the cells could sustain autonomous growth and replication in semi-suspension culture in the absence of any exogenous protein. Under electron microscopy, these  protein-independent  cells  exhibited  ringed  nuclei,  frequent  binucleism,  dense elongated mitochondria, and carbohydrate inclusions. In addition, there was abrogation of DR, DQ, Leu 8, CD23, CD25, CD38, and CD71. The conditioned medium (CM)  from either the serum-free or the protein-free WB culture contained two novel proteins, namely 21 and 53 kilodaltons  (Kd)  moeities  with  respective  necrotic  and  growth  bioactivity.  Hence, availability of  this  cell  line would allow for easy purification of  these important secretory proteins, and for the production of human monoclonal antibodies. Also,  further study of the cell line may provide the answer as to how cancer cells could gain autonomy in a milieu of apoptosis.     DESCRIPTION OF FIGURES     Figure 1. Transmission-electron micrograph of a representative WB cell showing inclusion bodies, stratified  rough  endoplasmic  reticulum  (RER),  and  a  heterochromatic  thicked-rimmed, irregular large nucleus with a prominent   nucleolus. Magnification: 26,000X.     Figure 2. Transmission-electron  micrograph   of  a  ringed  nucleus  surrounding  a  central  vacuole displayed by an occasional protein-independent WB cell. Magnification: 26,000X.     Figure 3. Transmission-electron micrograph of a representative binucleism shown by several protein-independent WB cells. Magnification: 26,000X.     Figure 4. Transmission-electron micrograph of dense elongated mitochondria and inclusion bodies found in the protein-independent WB cell. Magnification: 26,000X.
Patent CA-2114560-C (CA)
Title: Manufacture of high proof-test optical fiber using sol-gel
Inventor: BHANDARKAR SUHAS DATTATREYA
IPC: C03B37/016
Filed: 1994-01-31
Granted: 1999-09-07
Abstract: Optical fiber drawn froth preforms including sol-gel-derived glass is found to contain small refractory particles of the order of a micron in size. These particles initiate fiber breaks with the result that fiber may not meet proof-test tensile strength requirements. An effective separation method relies upon density and/or sire difference from suspended sol particles for separation in the ungelled sol. A preferred separation procedure is centrifugation.
Patent CA-2114592-C (CA)
Inventor: GARCIA SALVADOR
IPC: H04N1/00
Filed: 1994-01-31
Granted: 2002-06-18
Abstract: Procédé de fixation sur la bâti d'un appareil tel qu'un télécopieur, des organes de maintien des moyens élastiques de mise en pression des contre-galets d'entraînement des feuilles de papier. A cet effet, il comprend les étapes consistant à appliquer lesdits organes de maintien sur lesdits moyens élastiques de manière à comprimer ces derniers, à amener lesdits organes de maintien en position d'emboîtement dans des moyens appropriés du bâti, et à provoquer et maintenir ledit emboîtement par l'effort de compression desdits moyens élastiques.
Patent CA-2117265-C (CA)
Title: Enhanced skin penetration system for improved topical delivery of drugs
Inventor: DECKNER GEORGE E
IPC: A61K8/00
Filed: 1992-10-13
Granted: 2000-08-01
Abstract: The invention relates to pharmaceutical compositions for topical application comprising a safe and effective amount of a pharmaceutical active, and from about 0.1 % to about 10.0 % of a high molecular weight cationic polymer. These compositions provide enhanceed penetration of the pharmaceutical active.
Patent CA-2122501-C (CA)
Inventor: WAGGOTT JOHN
IPC: F16K31/12
Filed: 1994-04-29
Granted: 2004-04-13
Abstract: A substantially cylindrical, plug-type configuration of the element offers a mass which is less responsive to non-uniform and unsteady pressures, and channeling therein opens centrally, and about the periphery thereof, onto a recess formed in an end of the element which closes onto a valve seat. The channeling and recess are cooperative to assure that the balance-end of the element will have average, representative pressures conducted thereto.
Patent CA-2126344-C (CA)
Inventor: AASEN STEVEN M
IPC: A61K6/891
Filed: 1992-12-30
Granted: 2003-05-20
Abstract: The invention provides a pretreatment method and primer that is applied directly to the hard tissue. The invention has par-ticular utility for adhering to or coating sclerotic dentin and cervical enamel or for adhering to or coating hard tissue in a high humidity environment. The primer enables formation of extremely strong bonds to dentin. The method comprises tie steps of: (a) applying to the hard tissue adhesively effective amounts of an acid and a waterdispersible film former comprising a polymer and (b) hardening the film former. Primer compositions are provided far use in this method, comprising a mixture of an acid and a film former comprising a polymer prior to hardening, the mixture being in the form of a film atop the hard tissue.
Patent CA-2129117-C (CA)
Inventor: WHITE MARK D
IPC: C12Q1/30
Filed: 1993-01-28
Granted: 1999-01-05
Abstract: In biological assays in which hydrogen peroxide is used as an oxidizing agent, or wherein hydrogen peroxide is used to oxidize a dye or other intermediate to generate a detectable species, the stability of the hydrogen peroxide in the presence of catalase and other enzyme which decomposes hydrogen peroxide is enhanced by the addition of a suitable inhibitor for the enzyme. When catalase is the enzyme to be inhibited, catalase inhibitors that can be used in such biological assay systems include hydroxylamine salts such as hydroxylamine hydrochloride and hydroxylamine sulfate, and sodium azide. The enzyme inhibitor can be incorporated in an integral analytic device.
Patent CA-2130086-C (CA)
Inventor: HALLDIN CLAES
IPC: B01D53/34
Filed: 1993-03-04
Granted: 2004-04-13
Abstract: In a method for cleaning polluted gas and/or cooling of hot gas, and a device for carrying out the method, the gas is contacted with finely divided liquid. The finely divided liquid is supplied in the form of essentially umbrella-shaped shells or essentially linear curtains, in a regular arrangement, distributed in two or more planes substantially perpendicular to the main flow direction of the gas. The finely divided liquid is supplied such that the gas is alternately concentrated and spread by the impulse action exerted by the liquid on the gas in directions perpendicular to the main flow direction of the gas. The orthogonal distance between adjacent planes in which finely divided liquid is supplied, is so adjusted that no substantial equalisation of the gas flow takes place between the planes. The supply of liquid in adjacent planes is so arranged that it, in a plane located downstream in the flow direction of the gas, takes place where the flowing gas has been concentrated by the impulse action of liquid supplied in the plane located immediately upstream.
Patent CA-2133185-C (CA)
Title: Vertical gas turbine system
Inventor: UEKUSA HISAO
IPC: F01D25/28
Filed: 1994-09-28
Granted: 2004-09-21
Abstract: A gas turbine system having a gas turbine accommodated in a soundproof enclosure, a reduction gears connected to the gas turbine, and a pair of inlet and exhaust air silencers attached to an inlet pipe and an exhaust pipe, respectively, of the gas turbine, wherein the gas turbine and the reduction gears are a vertical gas turbine and a vertical reduction gears, which are stacked up, and shafts thereof are connected vertically, the vertical gas turbine and vertical reduction gears are accommodated in the soundproof enclosure, to thereby reduce the planar installation space of the gas turbine system.
Patent CA-2141691-C (CA)
Title: Solid pharmaceutical dosage forms having an extended two-stage release profile and production thereof
Inventor: NURNBERG EBERHARD
IPC: A61P25/28
Filed: 1993-08-04
Granted: 2002-04-09
Abstract: The present invention provides solid pharmaceutical compositions in dosage form containing an active ingredient ar princ-iple, preferably memantine, which exhibit an extended two-phase release profile and which are characterized by the presence of both a water-soluble and a water-insoluble salt of casein, preferably sodium and calcium caseinate, in the matrix thereof, in broad proportions and in a total amount between 5 and 98% by weight of the composition, and with a process for the production there-of.
Patent CA-2147893-C (CA)
Inventor: SCHINAZI RAYMOND F
IPC: C07D411/04
Filed: 1993-10-28
Granted: 1999-06-22
Abstract: The invention is a method for the treatment of humans infected with HBV that includes administering an HBV treatment amount of an enatiomerically pure .beta.-D-dioxolanyl purine nucleoside of formula (I), wherein R is OH, Cl, NH2 or H, and X is selected from the group consisting of alkyl, acyl, monophosphate, diphosphate, and triphosphate, or its pharmaceutically acceptable salt.
Patent CA-2151125-C (CA)
Title: Hydrocarbon gels useful in formation fracturing
Inventor: SMITH KEVIN W
IPC: C07F15/02
Filed: 1995-03-01
Granted: 1996-06-25
Abstract: This invention relates to improved hydrocarbon gels which find use in the fracturing of petroleum producing formations.  In particular it relates to the use of a defined class of gelling agents for hydrocarbons which provide excellent results in such fracturing.  The gelling agents comprise combinations of ferric salts and selected orthophosphate esters.
Patent CA-2155267-C (CA)
Title: Pre-compensated frequency modulation (pfm)
Inventor: CROZIER STEWART N
IPC: H03F1/32
Filed: 1995-08-02
Granted: 2001-05-15
Abstract: A system for transmitting FM signals comprised of apparatus for receiving an input data signal, apparatus for precompensating the received data signal, apparatus for applying the precompensated data signal to a constant envelope modulator to provide a modulated signal, apparatus for applying the modulated signal to a power efficient non-linear amplifier and transmitting a signal resulting therefrom, apparatus for receiving the transmitted signal in an I-Q receiver, and apparatus for filtering the received transmitted signal for the precompensation, to obtain an output data signal representative of the input data signal.
Patent CA-2157259-C (CA)
Inventor: TAMURA KOETSU
IPC: H05K3/34
Filed: 1995-08-30
Granted: 2000-08-29
Abstract: An  electronic  device  assembly  includes  a  large-scale integrated circuit (LSI) chip mounted on a flexible substrate.          The flexible substrate is connected to a second substrate via solder.  The flexible substrate is also attached to the second substrate via a resin.  When the assembly is manufactured, the solder is provided between the substrates.  The resin fills an area between the substrates.  The solder and the resin are heated simultaneously.   The solder melts to electrically connect the substrates.    The  resin  is  set  to mechanically couple  the substrates.
Patent CA-2157684-C (CA)
Title: Appareil de repartition de la chaleur pour grils au gaz
Inventor: MASHBURN JERRY P
IPC: A47J37/07
Filed: 1994-03-02
Granted: 1998-12-08
Abstract: L'invention porte sur un appareil (30) qui répartit la chaleur entre la source de chaleur (34) et la grille (31) d'un barbecue à gaz ou une bouilloire.  L'appareil vaporise et contrôle les liquides alimentaires qui coulent à travers la grille de cuisson et convertit facilement les caractéristiques de cuisson d'un barbecue à celles d'une cuisinière si besoin est.  Il est composé de deux parties articulées : une plaque plane perforée (10) et un capuchon (20).  La plaque est disposée horizontalement de sorte qu'une ouverture (13) se trouve directement au-dessus d'un brûleur à gaz (34).  De plus, elle comprend une série de dents (11) se prolongeant vers l'intérieur et vers le haut et placées autour de l'ouverture (13) afin de soutenir un récipient de cuisson (40) juste au-dessus de la source de chaleur (34) pour une cuisson de style cuisinière.  Le capuchon (20) se place par-dessus l'ouverture (13) afin de répandre la chaleur du brûleur à gaz (34) pour obtenir une cuisson traditionnelle de style barbecue.
Patent CA-2158173-C (CA)
Title: Method of treating addictive behaviors
Inventor: HITZIG PIETR
IPC: A61K31/135
Filed: 1994-03-17
Granted: 2001-12-04
Abstract: Treatment of addictive behavior, depression or manic depressive behavior, excluding obesity, is described in which an effective amount of at least one serotonin agonist and at least one dopamine agonist is administered to a patient. The combination of the serotonin agonist and the dopamine agonist are present in an amount effective to treat the patient's addictive behaviar. Pharmaceutical compositions are also disclosed.
Patent CA-2159306-C (CA)
Inventor: YOSHIKAWA KAZUHIRO
IPC: F16J3/02
Filed: 1995-09-27
Granted: 1998-08-18
Abstract: A diaphragm valve comprises a body having an inflow passage, outflow passage, valve chamber and valve seat, a metallic diaphragm for maintaining air-tightness of the valve chamber, a bonnet for securely holding the edge portion of the outer circumference of the metallic diaphragm in cooperation with the body, a stem inserted through and supported by the bonnet but movable up and down, and a valve disk inserted through a center opening in the metallic diaphragm.  The valve disk comprises a seat portion of disk-like shape contacting with and moving away from the valve seat, a shaft portion provided on the top surface of the seat portion and inserted through the opening in the diaphragm, and a connecting portion provided at the top end of the shaft portion and connected to the bottom end portion of the stem.  An end edge portion of the inner circumference of the diaphragm is welded to the disk valve shaft portion over the entire circumference of the shaft portion at a location spaced from the seat portion so that a large gap exists between the upper surface of the seat portion and the lower surface of the diaphragm, thereby improving gas substitution performance.
Patent CA-2160984-C (CA)
Title: Fibres textiles a base de poly(p-phenyleneterephtalamide)
Inventor: BOWEN MICHAEL WILLIAM
IPC: D01F6/60
Filed: 1994-04-12
Granted: 2000-09-26
Abstract: Fibre textile en téréphthalamide de poly-p-phénylène sulfoné qu'on peut teindre rapidement en nuances profondes.
Patent CA-2161921-C (CA)
Title: State machine architecture for concurrent processing of multiplexed data streams
Inventor: CARR LARRIE
IPC: H04B10/27
Filed: 1995-11-01
Granted: 1999-12-28
Abstract: A plurality of data streams time-division multi-plexed into a single stream are concurrently processed. State vectors characteristic of each data stream are stored in unique read-write memory locations having known ad-dresses.  During an initial clock cycle the next sequential data word is received from the single data stream and an input state vector characteristic of the data stream in which the received data originated is retrieved from the memory.   The data word and the input state vector are passed to state machine logic which, during one or more intermediate clock cycles, processes the data word and the input state vector to produce an output data word and an output state vector.  During a final clock cycle the output data word is transferred to an outgoing data stream and the output state vector is stored in the memory location from which the input state vector was retrieved.  The process repeats sequentially, with the next group of three clock cycles commencing immediately after the initial clock cycle of the immediately preceding group of three clock cycles.
Patent CA-2174829-C (CA)
Inventor: KEATOR CHRISTIAN G
IPC: A47B43/02
Filed: 1996-04-23
Granted: 2006-10-31
Abstract: A multi-tier display rack is formed from a flat blank of sheet material. The sheet material includes four panels which create front, rear and opposed side walls of the display rack. In a preferred embodiment, one panel includes sections which are partially punched out to form shelves of the display rack. Each shelf includes a slot therethrough. Another panel includes locking tabs which are partially punched out and pushed through the slots to lock the shelves in place.
Patent CA-2175133-C (CA)
Inventor: ROKUGO YOSHINORI
IPC: H03L7/191
Filed: 1996-04-26
Granted: 2000-04-04
Abstract: Using positive-phase or negative-phase clocks of phase count clock Pf0, a number M of multilevel quantized phase comparators output as values quantized in multiple levels the phase differences of output signals outputted from first and second N-stage frequency dividers wherein input clocks and output clocks, respectively, of a digital PLL have been N-stage frequency divided and moreover, divided into M groups. An adder adds this phase difference information and outputs advanced pulses or delayed pulses.  An N1 counter counts up in response to advanced pulses and both outputs an increment pulse and undergoes setting to initial value N1 upon counting up to 2N1.  In response to delayed pulses, the N1 counter counts down, and upon counting down to "0" both outputs a decrement pulse and undergoes setting to initial value N1.
Patent CA-2178528-C (CA)
Title: Therapeutics containing 5alpha - reductase inhibitors
Inventor: TAKAHASHI HIDEHIKO
IPC: A61K31/045
Filed: 1996-06-07
Granted: 2000-07-18
Abstract: Strong 5.alpha.-reductase inhibitors are  extracted and fractionated from Thuja orientalisis and other similar crude drugs or they may be purified as diterpenes in isolated form.          The inhibitors are used either on their own or as active ingredients of therapeutics in the treatment of diseases caused by the overactivity of 5.alpha.-reductase or the hypersecretion of androgens, such as male pattern  baldness, androgenetic alopecia, hirsutism, acne, prostatomegaly and cancer of the prostate.
Patent CA-2180570-C (CA)
Title: Isolated p27 protein and its encoding nucleic acid molecules
Inventor: MASSAGUE JOAN
IPC: C12N1/21
Filed: 1995-01-09
Granted: 2002-03-26
Abstract: The subject invention provides an isolated protein having an apparent molecular weight of about 27 kD and capable of binding to and inhibiting the activation of a cyclin E-Cdk2 complex. The subject invention also provides the nucleic acid encoding the p27 protein, vectors, and host cells for producing the recombinant form of the p27 protein. The subject invention further provides methods for identifying agents capable of modulating the ability of p27 to inhibit the activation of the cyclin E-Cdk2 complex. Finally, the subject invention provides methods for treating subjects diagnosed with hypoproliferative disorders using said agents.
Patent CA-2181373-C (CA)
Title: High-density fiber distribution frame
Inventor: WHEELER TODD A
IPC: G02B6/38
Filed: 1994-11-16
Granted: 2005-10-18
Abstract: A fiber distribution frame includes a fixture having a plurality of modules mounted side-by-side within said fixture with each of the modules being individually mounted in a line of travel. Each of the modules can be locked in any one of a plurality of discrete positions within the line of travel. Each of the modules contains a plurality of adapters for receiving and retaining fiber optic connectors. Further, the fixture may be tilted downwardly to provide access to the rear of the fixture.
Patent CA-2182390-C (CA)
Title: Process for producing bactericidal/fungicidal plastic bodies
Inventor: KRALL THEODOR
IPC: A01N59/16
Filed: 1995-02-01
Granted: 2006-12-19
Abstract: Objects for use in medical application that are produced from plastics required to have an antimicrobially effective content of metals (or metal compounds) can be produced inexpensively by coating a plastic blank in the form of film, granules or fibers with the desired metal (or metal compound) according to the methods used in thin-film technology. The thus obtained intermediate is subsequently comminuted and mixed and, as the starting product for the desired final form, further processed.      As a result, these objects are antimicrobially effective on every area of their surface, i.e. also on internal surfaces.      The amount necessary for full effectiveness of the antimicrobially active substances, which in the case of the subject-matter of this invention are oligodynamically active metals (or metal compounds), is only a small percentage of that necessary when they are introduced into the plastic in the form of powder, which fact results in considerable financial advantages.
Patent CA-2187389-C (CA)
Title: A process for producing a liquid impermeable and flushable web
Inventor: AHR NICHOLAS ALBERT
IPC: A61L15/62
Filed: 1996-10-08
Granted: 2000-08-22
Abstract: A process for impregnating a resin into a substrate to form a web. The resin is impregnated into one side of the web, so that the other side remains exposed. This arrangement allows the exposed side of the web to be dispersible in water, while the impregnated side is water resistant. The impregnation may occur in zones and comprise one material or two or more materials. The resulting web is useful as abacksheet in disposable absorbent articles wherein it is desired to have a barrier that is impermeable to body fluids, yet flushable for disposal.
Patent CA-2191564-C (CA)
Inventor: MURATA SUSUMU
IPC: C11D3/37
Filed: 1995-05-30
Granted: 2000-08-01
Abstract: A detergent composition containing at least 10 % detergent surfactant; and at least 10 % detergent builder system. The detergent builder system contains a polycarboxylate agent having an Index Ratio (IR) of not less than 100, wherein IR = Binding Index (BI) x Dispersing Index (DI)/100. Preferred are copolymers of maleic and acrylic acid, and salts thereof, having a molecular weight between 5,000 and 15,000. Such polymers provide hardness binding capacity and excellent clay soil dispersion, even under underbuilt wash solution conditions.