baber/WOPTO huggingface dataset:
Patent MX-2007000976-A (MX)
Title: Combination therapy for diabetes, obesity, and cardiovascular diseases using gdf-8 inhibitors.
Inventor: TOBIN JAMES F
IPC: A61K39/00
Filed: 2005-08-11
Abstract: A method of treating obesity, cardiovascular diseases, and disorders of insulin metabolism in a subject, comprising administering to the subject a therapeutically effective amount of a GDF-8 inhibitor, and a therapeutically effective amount of at least one other therapeutic agent which treats the targeted syndrome.
Patent MX-2007001039-A (MX)
Title: Nozzle blade airfoil profile for a turbine.
Inventor: VANDEPUTTE THOMAS W
IPC: F01D9/00
Filed: 2007-01-25
Abstract: First stage stator vanes for a turbine comprised airfoil profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in inches in Table I, which define a plurality of radially spaced profile sections forming the nominal profile. The Z coordinate values for each profile section are radial distances from the turbine axis to a portion of the surface of revolution about the axis containing the profile section. The X and Y values for each profile section are coordinate values which, when connected by smooth continuing arcs define the airfoil profile section along the surface of revolution portion. The radially spaced profile sections are joined smoothly with one another to form the nominal airfoil profile.
Patent MX-2007001351-A (MX)
Title: System and method for transfer of feedback control for a process control device.
Inventor: SEBERGER STEPHEN G
IPC: G05B19/00
Filed: 2005-08-02
Abstract: Disclosed herein is a controller and method useful for transferring control of a process control device between first and second control modes. The controller includes first and second servo control modules that generate first and second drive signals based on feedback information from first and second sensors for control of the process control device in accordance with first and second control modes, respectively. The controller also includes a feedback control transfer module that transfers control of the operation of the process control device from the first control mode to the second control mode based on the feedback information from the first sensor. In certain embodiments, such control transfer involves a control routine that initially generates the second drive signal based on the first drive signal to effectuate a smooth, bumpless transfer between the control modes.
Patent MX-2007001740-A (MX)
Title: Methods for identifying messages and communicating with users of a multimodal message service.
Inventor: ANDERL EWALD
IPC: H04W4/14
Filed: 2005-08-12
Abstract: Methods for combining speech with existing text wireless Short Message Service (SMS) to create a multimodal SMS service are provided. A user of standard SMS text service is provided with a link within each message that allows adding or retrieval of a voice message associated with an SMS text message. A speech server in the wireless network may be used for recognition of voice commands, rendering of test into speech, and recording or playing back voice recordings. An automatic and unique identification of each message is created to allow retrieval of the message without manually selecting the message. Additional services include message lists, integration with voicemail systems, image and video messages, cross-functional applications with Multimedia Messaging Services (MMS) and Enhanced Message Services (EMS), and extensions of the combination of voice with text SMS to other computing devices such as PDAs and PCs.
Patent MX-2007002626-A (MX)
Title: Anti-bacterial compounds.
Inventor: DERRER SAMUEL
IPC: A01N37/00
Filed: 2005-08-31
Abstract: Ester compounds of the formula I-a wherein R1 is selected from OH, NH2 and NH3+X-, wherein X is an inorganic anion, wherein R2 is a singly-branched saturated or unsaturated aliphatic hydrocarbon moiety selected from C7 - C15, wherein R5 is selected from H, and a linear saturated or unsaturated aliphatic hydrocarbon moiety selected from C6 - C14, and wherein R2 and R5 together have a total of 7 to 15 carbon atoms; that are useful as antibacterial or antifungal compounds in consumer products.
Patent MX-2007003359-A (MX)
Title: Mobile communication terminal and information display method thereof .
Inventor: KIM HYUN HO
IPC: H04M1/72439
Filed: 2007-03-21
Abstract: A mobile communication terminal and an information display method thereof are disclosed. The information display method comprises displaying information on a display unit of the mobile terminal, generating a scrolling start signal and scrolling the information with a positive acceleration based on the generated scrolling start signal.
Patent MX-2007003823-A (MX)
Title: Buoyant detectable cable tie .
Inventor: LAPORTE RICHARD
IPC: B65D63/00
Filed: 2007-03-29
Abstract: A buoyant cable tie formed from a composition that includes a plastic material and metal particles. The average density of the composition is less than 1.25 g/cm<3>, preferably less than 1.15 g/cm<3>, and the cable tie floats. In one embodiment, the plastic material has a first melting point and the plastic carrier material has a second melting point. The first melting point is lower than the second melting point so that the plastic material can be melted without melting the plastic carrier material. The cable tie floats and the metal particles allow the cable ties to be easily detected by metal detection devices. Some embodiments can also be detected by X-ray, sonar, optical or visual detection devices.
Patent MX-2007007068-A (MX)
Title: Fused bicyclic carboxamide derivatives for use as cxcr2 inhibitors in the treatment of inflammation.
Inventor: HEITSCH HOLGER
IPC: C07D261/08
Filed: 2005-12-17
Abstract: The invention relates to compounds of the formula (I) in which R1, R2, X, A, B, Dand Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceuticallyacceptable salt and/or a prodrug thereof. Because of their properties as inhibitorsof chemokine receptors, especially as CXCR2 inhibitors, the compounds of theformula I and the pharmaceutically acceptable salts and prodrugs thereof aresuitable for the prevention and treatment of chemokine mediated diseases suchas inflammatory diseases.
Patent MX-2007009349-A (MX)
Title: Site-specific serine recombinases and methods of their use.
Inventor: PADIDAM MALLA
IPC: C07H21/04
Filed: 2005-02-08
Abstract: The present invention provides a method for obtaining site-specific recombination in a eukaryotic cell, the method comprising providing a eukaryotic cell that comprises a first recombination attachment site and a second recombination attachment site; contacting the first and second recombination attachment sites with a prokaryotic recombinase polypeptide, resulting in recombination between the recombination attachment sites, wherein the recombinase polypeptide can mediate recombination between the first and second recombination attachment sites, the first recombination attachment site is a phage genomic recombination attachment site (attP) or a bacterial genomic recombination attachment site (attB), the second recombination site is attB or attP, and the recombinase is selected from the group consisting of a Listeria monocytogenes phage recombinase, a Streptococcus pyogenes phage recombinase, a Bacillus subtilis phage recombinase, a Mycobacterium tuberculosis phage recombinase and a Mycobacterium smegmatis phage recombinase, provided that when the first recombination attachment site is attB, the second recombination attachment site is attP and when the first recombination attachment site is attP, the second recombination attachment site is attB. The invention also describes compositions, vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors and methods of the present invention are also useful in gene therapy applications.
Patent MX-2007009739-A (MX)
Title: Vertical wheel machine and method for compression molding sealing liners.
Inventor: WILLINGHAM WENDELL D
IPC: B29C31/04
Filed: 2006-06-05
Abstract: An apparatus for compression molding sealing liners in premade closure shells includes a shell loader (141) for presenting premade closure shells (122) in sequence, a mold charge placement device (132 or 214) for placing charges of liner material into the premade shells, and a vertical wheel molding machine (30 or 160) for receiving the closure shells in sequence from the loader and compression molding the mold charges to form sealing liners within the closure shells. The vertical wheel molding machine preferably includes a wheel (32 or 160) mounted for rotation around a horizontal axis and a plurality of angularly spaced molds (72 or 164) disposed around the wheel. Each of the molds preferably includes a first mold segment 976 or 166) and a second mold segment (78) disposed radially outwardly of the first mold segment. One of the first and second mold segments, preferably the second mold segment, includes a nest for receiving a premade closure shell. The other of the first and second mold segments, preferably the first mold segment, includes a core (80 or 168) for engaging and compression molding the mold charge of liner material within the shell.
Patent MX-2007013257-A (MX)
Title: Alpha aminoacid ester-drug conjugates hydrolysable by carboxylesterase.
Inventor: DAVIDSON ALAN HORNSBY
IPC: A61K47/48
Filed: 2006-05-04
Abstract: Covalent conjugation of an alpha amino acid ester to a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid, leads to accumulation of the carboxylic acid hydrolysis product in the cell and enables improved or more prolonged enzyme or receptor modulation relative to the unconjugated modulator.
Patent MX-2007014297-A (MX)
Title: Purine derivatives and their use for treatment of autoimmune diseases.
Inventor: ZACHARIE BOULOS
IPC: A61K31/52
Filed: 2006-05-15
Abstract: Compounds useful in the treatment of autoimmune disease are described by the following general formula (I): n = 0-2 m = 0-2 m is not necessarily equal to n; where R<sub>1</sub>, R<sub>3</sub> = NH<sub>2</sub>, F, Cl, C<sub>1</sub>-C<sub>4</sub> alkoxy or phenoxy group, but R<sub>1</sub> is not necessarily equal to R<sub>3</sub>; and R<sub>2</sub> = H, F, Cl, NH<sub>2</sub>, or NH- R- XH; where R = - (CH<sub>2</sub>)p - p = 2-4 = Formula (II), Formula (III) = Formula (IV) q = 0-3 X = CH<sub>2</sub>, NH, O, or S.
Patent MX-2007014928-A (MX)
Title: Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists.
Inventor: BINGGELI ALFRED
IPC: C07D401/14
Filed: 2006-05-23
Abstract: This invention is concerned with compounds of the formula (1) wherein R<sup>1</sup> to R<sup>5</sup>, R<sup>5'</sup> and A are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
Patent MX-2007015174-A (MX)
Title: Process of making an alpha-anomer enriched 2-deoxy-2,2-diflouro-d -ribofuranosyl sulfonate and use thereof for making a beta nucleoside.
Inventor: SCHLOEMER GEORGE
IPC: C07H19/00
Filed: 2006-05-24
Abstract: A process of preparing an alpha-anomer enriched 2- deoxy-2 , 2-dif luoro-D-ribofunanosyl sulfonate, which is useful as an intermediate in the preparation of a beta nucleoside, such as gemcitabine, an anti-tumor agent. A beta-2-deoxy-2, 2-difluoro-D-ribofunanosyl sulfonate is heated and converted to an alpha-2-deoxy-2, 2-difluoro-D- ribofunanosyl sulfonate in the absence of an effective amount of a sulfonate salt to facilitate the conversion. In addition, an anomeric mixture of an alpha-anomer and a beta-anomer of 2-deoxy-2, 2-difluoro-D-ribofunanosyl sulfonate can be dissolved in a mixture of water and a solvent and heated to produce a lactol, which may be further converted to jan alpha-anomer enriched 2-deoxy- 2 , 2-difluoro-D-ribofunanosyl sulfonate .
Patent MX-2007015881-A (MX)
Title: Sleeve insert for mitigating acoustic cavity resonances and related method.
Inventor: SOMMERVILLE DANIEL V
IPC: F16L55/00
Filed: 2007-12-13
Abstract: A main flow line and relief valve assembly comprising: a main line fitted with a standpipe; a relief valve fitted within the standpipe; and a sleeve inserted in the standpipe below the relief valve, with a distal end of the sleeve configured to prevent aero-acoustic resonances of the deep cavity formed by the relief valve and standpipe assembly. The aero-acoustic resonance is prevented by separating the vortex shedding frequency associated with the free shear layer convecting across the mouth of the deep cavity and the acoustic cavity frequencies of the deep cavity and by disrupting the free shear layer at the mouth of the deep cavity such that the vertical structure does not remain coherent and/or does not impact upon the downstream edge of the cavity mouth.
Patent MX-2008012328-A (MX)
Title: Malate salts, and polymorphs of (3s,5s)-7-[3-amino-5-methyl-piper idinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecar boxylic acid.
Inventor: GODLEWSKI JANE ELLEN
IPC: A61K31/47
Filed: 2007-03-26
Abstract: The present invention is directed to malate salts of (3S,5S)-7-[3-amino-5-methyl- piperidinyl]-l-cyclopropyl-l,4-dihydro-8-methoxy-4-oxo-3-quinol inecarboxylic acid, and its polymorphs. The present invention is also directed to pharmaceutical compositions comprising the described salts and polymorphs.
Patent MX-2008014116-A (MX)
Title: Lightning protection system for a wind turbine rotor blade and a method for manufacturing such a blade.
Inventor: BERTELSEN KIM
IPC: F03D11/00
Filed: 2007-05-08
Abstract: The invention relates to a wind turbine rotor blade (5) comprising a blade tip (10) and a lightning protection system. The rotor blade includes at least one lightning receptor (7) at the surface of the blade in an external distance (Lex) from the distal end of the blade tip (10), and a lightning receptor base (11) inside the rotor blade (5) arranged at an first internal distance (Lj1) from the distal end of the blade tip (10). To avoid arching from the blade surface (18), to the lightning receptor base (11) if the lightning does not strike the receptor (7), the rotor blade further includes means (22a) for changing at least one electric property of the rotor blade (5) at the lightning receptor base (11), as compared to the electric properties of ambient air. These means are filling a part of the blade with e.g. polyurethane. The invention further relates to a method for manufacturing a wind turbine rotor blade (5).
Patent MX-2008015195-A (MX)
Title: Delivery method.
Inventor: SULLENGER BRUCE A
IPC: A61K31/70
Filed: 2007-06-01
Abstract: The present invention relates, in general, to siRNA and, in particular, to a method of effecting targeted delivery of siRNAs and to compounds suitable for use in such a method.
Patent MX-2009003952-A (MX)
Title: Fluid level control valve.
Inventor: HAJJAR ELIAS
IPC: F16K31/383
Filed: 2007-10-16
Abstract: A valve device to control fluid supplied to a tank (123). The valve device includes a fluid inlet (101), a fluid outlet (120) to expel fluid to said tank (123), a valve seat (119), defining an opening through which fluid is adapted to flow from said inlet (101) to said outlet (120), a valve member (107), movable relative to said valve seat (119) between an open and a closed position, and, a control means to operate said valve device. The control means includes a control chamber (103), a fluid passageway (102) between said control chamber (103) and said inlet (101), a flow control element (104) within said fluid passageway (102), a relief valve (106), movable between an open and closed position to selectively expel fluid from said control chamber (103) to a relief port (121), and, a relief valve activation means, to control the operation of said relief valve according to the amount of fluid in said tank (123). The valve device (200) may be constructed in a multi-part form, including a main body portion (201) and a relief portion (202).
Patent MX-2009004528-A (MX)
Title: New phenylsulfamoyl benzamide derivatives as bradykinin antagonists.
Inventor: VAGO ISTVAN
IPC: C07D285/12
Filed: 2007-10-27
Abstract: The present invention relates to new sulfonamide derivatives of formula (I), wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
Patent MX-2009004821-A (MX)
Title: Mesh pouches for implantable medical devices.
Inventor: BUEVICH FATIMA
IPC: A61B19/00
Filed: 2007-11-06
Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The pouches of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use, and, optionally, include one or more drugs in the polymer matrix of the coating to provide prophylactic effects and/or alleviate side effects or complications associated with the surgery or implantation of the CRM or other implantable medical device.
Patent MX-2009008300-A (MX)
Title: Pre-applied protective jacketing construction for pipe and block insulation.
Inventor: WHITAKER THOMAS
IPC: F16L9/04
Filed: 2007-12-06
Abstract: A protective jacketing-insulation composite structure and method is provided for inhibiting the corrosion of a pipeline. The method includes forming a porous- insulation into an elongated-arcuate-shape, applying a sodium silicate solution layer to the insulation and at least partially within the pores thereof, permitting the sodium silicate solution layer to set to a threshold amount, adhering an outer facing to the sodium silicate solution layer after the permitting step is accomplished, installing the insulation and facing to the outer surface of a pipeline, and sealing any exposed edges or seams that may exist between multiple installed products. A structure such as made from this method can have a release layer and contact adhesive.
Patent MX-2009010320-A (MX)
Title: Oral contraceptive regimen.
Inventor: THOMAS JEAN-LOUIS
IPC: A61K31/565
Filed: 2008-03-26
Abstract: A monophasic method of achieving contraception in a human female comprising orally administering to the human female a composition comprising 1.5 mg of 17-beta-estradiol and 2.5 mg of nomegestrol acetate for 24 days followed by a hormone-free period of 4 days.
Patent MX-2009011769-A (MX)
Title: Pyridone derivatives as p38a mapk inhibitors.
Inventor: YAMAZAKI HITOSHI
IPC: A61K31/4412
Filed: 2008-05-02
Abstract: A compound represented by the formula (I): wherein R1 is lower alkyl, cycloalkyl or aromatic hydrocarbon ring, each of which is optionally substituted with one or more substituents; R2 is hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and R3 is (1) a group represented by the formula: wherein R4 is lower alkyl, etc.; (2) a group represented by the formula: wherein R5 is lower alkyl, etc.; (3) a group represented by the formula: wherein R6 is lower alkyl, etc.; or (4) a group selected from halogen atom, carboxy, hydroxy and lower alkoxy, or a salt thereof.
Patent MX-2009012623-A (MX)
Title: Heterocyclic kinase modulators.
Inventor: BOUNAUD PIERRE-YVES
IPC: A61P19/02
Filed: 2008-05-21
Abstract: The present disclosure provides heterocyclic protein kinase modulators and methods of using these compounds to treat diseases mediated by kinase activity.
Patent MX-2009012812-A (MX)
Title: Mutated parvovirus structural proteins as vaccines.
Inventor: HALLEK MICHAEL
IPC: C12N15/864
Filed: 2008-06-02
Abstract: The present invention is related to a method for identifying a parvovirus mutated structural protein capable of specifically binding to a binder for an antigen, a parvovirus mutated structural protein which comprises at least one B-cell epitope heterologous to the parvovirus, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a virus or cell comprising the protein, a method of preparing the protein, a medicament comprising the protein, nucleic acid or multimeric structure and its use.
Patent MX-2010001658-A (MX)
Title: Invert emulsion fluid systems comprising an emulsified aqueous phase comprising dispersed integral latex particles.
Inventor: XIANG TAO
IPC: C09K8/24
Filed: 2008-07-28
Abstract: An invert emulsion fluid system and a method of performing petroleum recovery operations using an invert emulsion fluid system.
Patent MX-2010002816-A (MX)
Title: Method for determining the optimal insertion force of a fastener press.
Inventor: PATTON ROGER B
IPC: B21J15/28
Filed: 2008-11-06
Abstract: Force data is monitored by a strain gauge during a preparatory setup operation of an insertion process during which a sample fastener is installed into a host material by a fastener press. Mathematical algorithms are utilized to determine an optimal insertion force, while a predetermined insertion velocity is maintained throughout the installation process regardless of the force required. With the ram velocity held constant, the insertion force is measured during the installation process and compared to the elapsed time to obtain a force slope. A data point on the force slope which corresponds to the point at which the force slope abruptly increases is captured and recorded as the optimal insertion force. This optimal force is then used by the press for all fasteners/host-material installations of the sample type.
Patent MX-2010003717-A (MX)
Title: Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof.
Inventor: FARINA JAMES
IPC: A61K9/20
Filed: 2008-10-07
Abstract: An improved excipient comprising substantially homogeneous particles of a compressible, high functionality granular microcrystalline cellulose based excipient is provided. The improved excipient comprises microcrystalline cellulose, a binder and a disintegrant, and is formed by spraying a homogeneous slurry of the components. The excipient provides enhanced flowability/good flow properties, excellent/high compactibility, and increased API loading and blendability as compared to the individual components, and as compared to conventional excipients formed from the same materials. The improved excipient has strong intraparticle bonding bridges between the components, resulting in a unique structural morphology including significant open structures or hollow pores. The presence of these pores provides a surface roughness that is the ideal environment for improved blending with an API.