baber/WOPTO huggingface dataset:
Patent CA-2301862-A1 (CA)
Inventor: SHIMKETS RICHARD A
IPC: G01N33/15
Filed: 1998-08-20
Abstract: The present invention is based upon the observation that a mutant atrial natriuretic factor (ANF) gene increases stroke latency in spontaneously hypertensive rats-stroke prone (SHRSP). Accordingly, the present invention provides methods using mutant ANF proteins, fragments, analogs, derivatives and homologs of mutant ANF proteins, the nucleic acids encoding these mutant ANF proteins, as well as modulators of ANF for treating or preventing ischemic diseases, in particular ischemic stroke. The invention also relates to methods of diagnosis, prognosis and screening for a disposition for diseases and disorders associated with increased levels of ANF. Pharmaceutical compositions, methods of screening for ANF mutants and ANF modulators with utility for treatment and prevention of ischemic stroke are also provided.
Patent CA-2302268-A1 (CA)
Title: Snowboard safety release binding
Inventor: SCALLION DAVID
IPC: A63C10/18
Filed: 1998-09-30
Abstract: A binding apparatus for a snowboard with which the boots of a snowboarder can be securely attached to the board whilst permitting release thereof upon application of a force greater than a preselected threshold. If a force of an undesirable magnitude in either a lift-out or torsional direction is applied to either of the snowboarder's boots with respect to the board, then that boot will be released by the binding, and the other binding will also automatically release the other boot. Both boots can also be manually released from the bindings, and one boot can be left secured to the board whilst the other is released for negotiating ski lifts and the like. The snowboard bindings permit easy step-in entry which will allow the boot to be secured to the binding even in the event of snow or the like being stuck between the boot and binding. A  safety brake is also provided which prevents run-away of the board if it is detached from the rider.
Patent CA-2303948-A1 (CA)
Title: Integrated wavelength-select transmitter
Inventor: BALL GARY A
IPC: G02B6/42
Filed: 1998-09-10
Abstract: An integrated optical transmitter for use in an optical system has an optical head assembly with an optical beam generator for providing an optical beam and a lens assembly collecting the optical beam and generating therefrom a formed optical beam. Interface optics receive the formed optical beam and provide optical coupling so as to minimize insertion loss to the optical beam. Also included is an optical modulator for receiving the optical beam from the interface optics and for providing a modulated optical beam in response to received modulation signals. The optical modulator is coupled to the interface optics to be in a fixed relationship therewith.
Patent CA-2305553-A1 (CA)
Inventor: DENT PAUL W
IPC: H04L1/20
Filed: 1998-09-30
Abstract: A method and apparatus for protecting a first group of data bits using a second group of data bits within digital data transmissions is disclosed. First and second groups of data bits are encoded for transmission in a communication network. The second group of encoded data bits are scrambled using a scrambling mask generated from the first group of data bits. The first group of encoded data bits and the second group of encoded and scrambled data bits are then interleaved and transmitted to a receiver. The first group of data bits are decoded and used to regenerate the scrambling mask to descramble the second group of encoded and scrambled data bits. The second group of data bits may then be decoded. The results of the decoding of the second group of data bits are used to determine whether or not the first group of data bits were properly decoded.
Patent CA-2306918-A1 (CA)
Title: Muscle stimulating device and method for diagnosing and treating a breathing disorder
Inventor: GAUMOND ROGER PAUL
IPC: A61N2/04
Filed: 1998-10-15
Abstract: This invention is a device (30), a method for magnetic stimulation of muscles for the diagnosis, and relief of a breathing disorder, such as obstructive sleep apnea. Magnetic stimulation is used to stimulate muscles which serve to stabilize the upper airway of an individual whose nocturnal apneic events are related to diminished muscle tone. A sensor (38) monitors a physiologic characteristic of the patient, a coil (56) is energized to stimulate the appropriate muscles associated with the upper airway, a power supply provides power for energizing the coil (56), and a control system (32) controls the application of power to the coil (56) based on the output of the sensor (38). Diagnosis of obstructive sleep apnea is accomplished by measuring the subject's compliance in the presence, and absence of the magnetic stimulation of the upper airway muscles. The smaller the difference between these two compliance levels, the more likely that patient suffers from obstructive sleep apnea.
Patent CA-2307425-A1 (CA)
Title: Stabilisation system for soil slopes
Inventor: FABIUS MIKE
IPC: E02D17/20
Filed: 2000-05-03
Abstract: A method of stabilising slopes of a soil embankment is provided using a stabilisation system for slopes having generally less than 45 degrees of inclination from horizontal. The system comprises a plurality of soil nails which are penetrated into the slopes to provide internal soil stability and a biotechnical facing on a surface of the slope to inhibit surface erosion and shallow failure of the slope. A geosynthetic layer comprising a mat, mesh or fibrous material is laid across the slope adjacent the surface to assist in establishing vegetation thereon. A retaining wall structure is preferably mounted on the crest of the slope to extend transversely to the slope. The retaining wall structure at the crest provides a stable base for supporting the embankment shoulder.
Patent CA-2308031-A1 (CA)
Inventor: WOYCHIK RICHARD
IPC: C12N15/09
Filed: 1998-06-03
Abstract: A method for producing gene targeting constructs in bacteria by way of homologous recombination between bacterial phage and plasmids.
Patent CA-2309960-A1 (CA)
Inventor: PAUGSTADT RALF
IPC: B42D25/00
Filed: 1998-10-10
Abstract: A security feature for security documents or documents of value, comprising a transparent body (2) provided with devices for representing graphical information according to an angle (18, 19, 20) between the direction of illumination and the direction of observation. Said devices consist of almost overlapping laminae (7, 8) arranged in the form of steps in said body (2).  Preferably, the lamellae (7, 8) are fractally embodied and arranged in the body (2) in ascending order.
Patent CA-2310266-A1 (CA)
Inventor: LEE HYUN-SEOK
IPC: H04B7/26
Filed: 1999-09-14
Abstract: A communication device and method in a mobile communication system. The mobile communication system has a plurality of service entities and a plurality of logical channels mapped to each service entity. According to one embodiment of the present invention, a communication device at a reception side has a plurality of logical channel mappers for the respective logical channels and a plurality of physical channel multiplexers/demultiplexers for physical channels. Each logical channel mapper converts a received data block mapped on a logical channel to a traffic in a predetermined format. Each physical channel multiplexer/demultiplexer defines a traffic receivable form a logical channel mapper, receives the traffic from the logical channel mapper, and demultiplexes the traffic into a corresponding physical channel.
Patent CA-2312341-A1 (CA)
Title: Percussive tool
Inventor: HARDIE RONNIE
IPC: E21B4/14
Filed: 1998-12-11
Abstract: A percussion drill (10) has a tubular fluid transmitting body (14), with a drill bit (16) mounted on a drill bit support (20) itself mounted in body (14) via a spring (22) and splines (24). A mass (28) is spring mounted in the body (14) and is movable to impact on a face (26) of the support (20). Mounted to the mass (28) is a rotating valve (32) comprising two valve plates (34, 36). Each plate (34, 36) defines a slot (38, 40), such that rotation of one of the valve plates (36) relative to the other moves the slots (38, 40) into and out of alignment; the change in alignment of the slots (38, 40) alters the flow of drilling fluid through the valve (32), so altering the drilling fluid pressure force acting on the mass (28), so causing mass (28) to push against the spring (30), and impact on the drill bit support (20) providing a percussive action at the drill bit (16).
Patent CA-2314620-A1 (CA)
Inventor: CHIANG HERMAN
IPC: A63B33/00
Filed: 2000-07-26
Abstract: The invention relates to a type of swimming goggles with a nose-fitting bridge, comprising: two frames, two lenses accommodated on the two frames, a nose bridge connecting the two frames, and a headband device that is fitted to the outside edges of the two frames, characterized in that: said nose bridge has at least one face-fitting part, said face-fitting part forming recesses from the exterior surface of the nose bridge towards the frames, the bottom ends of said recesses are protruded to have proper contact with the ridge of the user's nose, so designed to enable the nose bridge of the swimming goggles to join the two frames, to have better contact with the ridge of the user's nose, to provide better comfort, and to ensure better resistance to water seepage.
Patent CA-2318097-A1 (CA)
Title: Method for producing completely ceramic inlays, crowns, bridges, partial bridges, frames for implants or super structures in the field of dentistry
Inventor: WOLZ STEFAN
IPC: A61C5/77
Filed: 1999-01-14
Abstract: The invention relates to a method for producing crowns etc. by producing a frame, for example, made of alumina, whereby a film is shrink-fitted on the die of a working model. The film is provided with a slip and the slip is baked on a frame after the film is removed. In order to accelerate the method and to avoid the loss of materials, the die is placed on a rotatable shaft. The slip is deposited with a tool. A drying process using a hot air dryer is carried out during and/or after depositing the slip. This method can also be carried out in a CNC machine with which the veneer ceramic is successively deposited. A separating agent similar to lipstick can be deposited in place of the film. Said separating agent melts at temperatures greater than 45°C when the spacer function is not used. The invention also relates to a crease-free shrink-fitting of the film. In addition, the invention shows how the infiltration itself can result in the ceramic furnace, whereby the frame lies on a base which absorbs the excess glass. The invention also relates to a dosing device for slip with which the slip is to be dosed on the shrink-fitted film in a uniform consistency.
Patent CA-2318565-A1 (CA)
Title: Method for improving the stability of a slurry
Inventor: LEHTINEN KARI
IPC: C09C1/02
Filed: 1999-02-23
Abstract: The invention relates to a method for improving the storability of an aqueous slurry which contains inorganic solids, in which method a peracid or a salt thereof is added to the slurry in an amount which is at minimum 200 g/one metric ton of dry solids, calculated as 100 per cent peracid.
Patent CA-2318719-A1 (CA)
Title: Chair control gas spring retainer for chair height reduction
Inventor: DAVIS KEITH L
IPC: A47C3/30
Filed: 2000-09-13
Abstract: A chair control mechanism for use with a single stage gas spring construction for chair height adjustability includes a main control housing having an upwardly directed opening and an upper control housing having a downwardly directed opening. The two housings are dimensioned and configured to nest with one another and are connected by pivot members. An aperture is provided in the main control housing for receiving an end of a gas spring. A bracket assembly is welded to the main control housing and has two apertures both vertically aligned with the aperture of the main control housing and spaced above the aperture of the main control housing. The apertures of the bracket assembly are dimensioned and configured to engage a tapered end of the gas spring and support the control mechanism thereon with the end of the gas spring recessed well up into the control mechanism.
Patent CA-2319168-A1 (CA)
Title: Hyperactive mutants of himar1 transposase and methods for using the same
Inventor: RUBIN ERIC J
IPC: C12N15/87
Filed: 2000-09-27
Abstract: Mariner-family transposable elements are active in a wide variety of organisms and are becoming increasingly important genetic tools in species lacking sophisticated genetics. The Himar1 element, a member of the mariner family, isolated from the horn fly, Haematobia irritans, is active in Escherichia coli when expressed appropriately. Using this fact, a genetic screen was devised to isolate hyperactive mutants of Himar1 transposase that enhance overall transposition from 4 to 50-fold as measured in an E. coli assay. These hyperactive Himar1 mutant transposases should enable sophisticated analysis of the biochemistry of mariner transposition and should improve efficiency of a variety of genetic manipulations involving transposition in vivo and in vitro such as random mutagenesis or transgenesis in a wide range of host cells than the transposable elements previously available.
Patent CA-2321071-A1 (CA)
Inventor: TOUSSANT JOHN WILLIAM
IPC: B65D43/16
Filed: 1999-03-15
Abstract: An articulable food container. The food container is articulable from and between a first open position to a second closed position. In the first open position the food container can receive food. Additionally, the user may eat from the food container while it is in the first open position. In the second closed position, the food container covers or encloses the food. The closed position is useful for storing the food, heating the food, transporting the food between the point of service and the point of consumption, and/or disposing of the remnants of the food once the meal is completed. The food container may take the form of a plate, bowl, tray, clam shell, or other known configurations.
Patent CA-2321675-A1 (CA)
Title: Oxygen-scavenging compositions and articles
Inventor: VENKATESHWARAN LAKSHMI N
IPC: B01D53/46
Filed: 1999-03-11
Abstract: Oxygen-scavenging compositions comprising an oxidizable metal component, an electrolyte component and a solid, non-electrolytic, acidifying component. When blended with soft, flexible polymeric resins, these compositions exhibit good oxygen-scavenging performance with improved oxidation efficiency relative to compositions containing an oxidizable metal component, an electrolyte, and an acidifying component combined with a more rigid thermoplastic resins. Selection of a thermally stable non-electrolytic, acidifying component is important when melt compounding the compositions into polymeric resins and particularly for extrusion coating applications. The compositions can be used directly as an oxygen absorbent resin melt-fabricated into a wide variety of oxygen-scavenging packaging articles or as concentrates in combination with other thermoplastic resins.
Patent CA-2322957-A1 (CA)
Title: Bouchon et ouvre-bouteilles
Inventor: PULESTON CYAN
IPC: B65D51/24
Filed: 1999-10-21
Abstract: Un ustensile combiné (30) comprend un corps en plastique d'une pièce présentant un anneau (21) destiné à retirer une capsule de bouteille ainsi qu'un bouchon oblong (31) dépassant sensiblement radialement à l'extérieur de l'anneau. L'anneau présente des faces terminales inclinées coniques vers le bouchon (24, 25) ainsi qu'une ouverture le traversant (26) entre les faces terminales et définies par une paroi tronconique (27), l'ouverture étant chanfreinée au niveau de l'extrémité à petit diamètre. Une plaque métallique (36) est moulée par insertion dans le bouchon et présente une lèvre (38) saillante radialement jusque dans l'ouverture de l'anneau au niveau de l'extrémité à petit diamètre. Les surfaces intérieure et extérieure de l'anneau sont recouvertes d'un matériau (40) amortissant le frottement, définissant des nervures (41) espacées circonférentiellement. Le bouchon est conique (32) et recouvert d'un manchon (45) amortissant le frottement présentant des nervures (46) circonférentielles saillantes vers l'extérieur.
Patent CA-2323928-A1 (CA)
Inventor: BUCHER MICHAEL
IPC: F16L37/098
Filed: 2000-10-19
Abstract: A coupling assembly for providing a fluid connection comprising a female connector, a tube, a retainer and a cap. The female connector defines a bore.  The bore extends axially inwardly into the connector from an entrance. An annular face is defined in the bore axially inwardly of the entrance. The tube is received within the bore. The tube has an enlarged upset. The retainer is disposed in the bore. The retainer has a member directly contacting the upset and extends to the annular face to retain the tube in the bore. The cap is slidably mounted on the tube and is attached to the female connector. The cap has a protrusion directly contacting the upset.
Patent CA-2324756-A1 (CA)
Title: Breast cancer lesion detection and localisation device
Inventor: SAMPALIS TINA
IPC: A61B90/10
Filed: 2000-10-31
Abstract: A method and a device provided for detecting and localising non-palpable breast cancerous lesions comprise detecting a breast lesion solely by scintimammography with 99m-Tc Sestamibi, and using gamma camera imaging and stereotactic technology for stereotactically localising the breast lesion. For doing so, the X, Y and Z co-ordinates of the lesion are determined. This is achieved typically by determining the Y co-ordinate by imaging, the X co-ordinate by imaging from a pair of directions extending through the lesion and disposed at a known angle to each other, and the Z co-ordinate by geometrical calculation from the known angle.
Patent CA-2329379-A1 (CA)
Inventor: SLUSKY RONALD D
IPC: H04M3/533
Filed: 2000-12-21
Abstract: A visitor is enabled to provision from a borrowed telephone (104) a visitor's mailbox (116) associated with the borrowed telephone number, which may also be associated with a telephone owner's mailbox (114). This provisioning being allowed without requiring administrative mailbox provisioning privileges, such as ones possessed by a telephone system administrator. In one embodiment of the invention, the visitor dials a mailbox setup telephone extension and indicates that he wants to set up a visitor's mailbox (116). The voice mail system (110) provisions the visitor's mailbox (116) and prompts the visitor for setup information, which the visitor enters and hangs up. The voice mail system (110) then activates the visitor's mailbox (116). The telephone owner's (114) and visitor's (116) mailboxes operate. concurrently. For example, while the visitor's mailbox (116) is active, a caller who wishes to leave a message may be directed to specify whether he desires to leave a message for the telephone owner or the visitor. Additionally, the message-waiting indicator is different for the two mailboxes. Once the visitor's mailbox (116) is deactivated, the system (110) returns to its prior operating state with respect to the telephone owner's mailbox (114), i.e. calls are no longer routed to the visitor's mailbox (116) and there is no longer a direction to chose between the two mailboxes. The visitor's mailbox (116) can be automatically deactivated either at a predetermined time or after a particular time period specified by the visitor.  When the visitor's mailbox (116) is deactivated its contents can be forwarded to another mailbox, or force-delivered. Provisioning the visitor's mailbox (116) in this manner allows the visitor to receive messages while using a borrowed telephone (104) without having to access the telephone owner's mailbox (114), allowing the visitor and the telephone owner to retain the privacy and the security of their messages.
Patent CA-2330660-A1 (CA)
Inventor: HUARD JOHNNY
IPC: A61K35/34
Filed: 1999-04-30
Abstract: Cette invention concerne des cellules dérivées de muscle, de préférence des myoblastes et des cellules souches dérivées de muscle, qui sont produits par génie génétique pour contenir et exprimer un ou plusieurs gènes hétérologues ou des segments fonctionnels de ces gènes, en vue d'apporter les produits géniques codés à des sites ou à proximité de sites de lésion, de maladie, d'anomalie ou de dysfonction musculosquelettique, osseuse, ligamentaire, méniscale, cartilagineuse ou uro-génitale. L'apport génique effectué par l'intermédiaire de myoblaste ex vivo de synthase d'oxyde nitrique inductive humaine et la production résultante d'oxyde nitrique au niveau ou à proximité du site de la lésion sont tout particulièrement utilisés dans cette invention en tant que traitement des dysfonctions du système uro-génital inférieur. Le transfert de gène ex vivo destiné au système musculo-squelettique comprend des gènes codant le facteur de croissance fibroblastique acide, le facteur de croissance fibroblastique basique, le facteur de croissance épidermique, le facteur de croissance de substances apparentées à l'insuline, le facteur de croissance d'origine plaquettaire, le facteur de croissance transformant bêta, le facteur de croissance transformant alpha, le facteur de croissance nerveuse et la protéine antagoniste du récepteur d'interleukine 1 ("IRAP"), la protéine morphogénétique osseuse ("BMP"), la protéine morphogénétique dérivée du cartilage ("CDMP"), le facteur de croissance endothéliale vasculaire ("VEGF") et les protéines sonores du type hérisson.
Patent CA-2331094-A1 (CA)
Title: Methods and useful intermediates for paclitaxel synthesis from c-7, c-10di-cbz 10-deacetylbaccatin iii
Inventor: ZYGMUNT JAN
IPC: C07D305/14
Filed: 1999-04-29
Abstract: The present invention relates to a method of producing paclitaxel or a paclitaxel analog comprising the esterification of C-7, C-10 di-CBZ baccatin III with an N-carbamate protected, C-2-protected 3-phenyl isoserine side chain. The C-7, C-10 carbobenzyloxy groups are then replaced with hydrogen and an acyl group is substituted at the C-3' nitrogen. The resulting compound is acylated at the C-10 hydroxyl position, and deprotected at the C-2' position by replacing the hydroxyl protecting group with hydrogen to produce paclitaxel or a paclitaxel analog. The present invention also relates to alternative methods of acylating a 10-hydroxy paclitaxel analog. The first method comprises dissolving a 10-hydroxy paclitaxel analog in an acceptable ether solvent therefor to form a first solution at a first temperature. The first solution is then cooled to a second temperature, and an alkali base is added to form an intermediate compound having a metal alkoxide at the C-10 position thereof, after which an acylating agent is then added. The second method comprises dissolving a 10-hydroxy paclitaxel analog in an acceptable ether solvent therefor. An alkali salt is added, and a trialkyl amine base or pyridine is next added, followed by the addition of an acylating agent. The present invention is additionally directed to a C-10 metal alkoxide chemical intermediate for use in producing paclitaxel or paclitaxel analogs.
Patent CA-2333633-A1 (CA)
Inventor: OLSON RICHARD ERIC
IPC: C07D487/04
Filed: 1999-06-18
Abstract: L'invention concerne de nouvelles pyrazolo[1,5-a]triazines qui correspondent à la formule (I): dans laquelle R?3¿ est un groupe alkyle, alcényle, alkynyle ou cycloalkyle, ou leurs sels pharmaceutiquement acceptables, qui sont utiles en tant qu'antagonistes du facteur de libération de corticotropine.
Patent CA-2335581-A1 (CA)
Title: Novel compounds useful in pain management
Inventor: PLOBECK NIKLAS
IPC: C07D213/89
Filed: 1999-06-16
Abstract: Compounds of general formula (I) are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain.
Patent CA-2337446-A1 (CA)
Title: Arc fault circuit interrupter recognizing arc noise burst patterns
Inventor: ROMANO JAMES P
IPC: H02H3/44
Filed: 2001-02-16
Abstract: An arc fault circuit interrupter (AFCl) detects arc faults by identifying the various signature patterns of arc fault noise while rejecting arc mimicking noise from, normal load phenomena.