baber/WOPTO huggingface dataset:
Patent NZ-228846-A (NZ)
Title: Microbeads containing diltiazem comprising a core containing the active substance surrounded by a microporous membrane of film forming polymer, capsules containing such microbeads
Inventor: DESMOLIN HENRI
IPC: A61K9/52
Filed: 1989-04-21
Abstract: The microspheres are composed of a core containing the active principle and a microporous membrane which is insoluble in aqueous media, the membrane consisting of a film-forming polymer, a plasticiser and a filler. The membrane has a thickness such that, in vitro, the diltiazem is released at a substantially constant rate for at least 6 hours, after a latency time of less than 1 hour. The active principle may be mixed intimately with the core, or coated in a layer of polyvinylpyrrolidone surrounding a carrier particle. The sustained-release microspheres are formed by application to the core of a dispersion of the constituents of the membrane in a solvent, and evaporation of the solvent. The pharmaceutical compositions consist of hard gelatine capsules containing the microspheres. They are administered, according to the dose, once to twice a day orally for the treatment of angina or hypertension.
Patent NZ-252098-A (NZ)
Title: 1-aryl-3-piperazino indane derivatives and medicaments
Inventor: BOGESO KLAUS
IPC: A61K31/495
Filed: 1993-04-23
Abstract: Trans isomers of 1-piperazino-1,2-dihydroindene compounds having formula (I),    <IMAGE>  I  wherein X and Y are hydrogen, halogen, trifluoromethyl, alkyl, alkylthio, trifluoromethylthio, alkoxy, hydroxy, alkylsulfonyl, amino, alkylamino, nitro or cyano; Ar is a phenyl, thienyl or furyl group, each optionally substituted; R1 is hydrogen, or optionally hydroxy substituted alkyl, alkenyl, cycloalkyl or cycloalkylalkyl; R2 is alkyl, alkenyl, cycloalkyl, or cycloalkylalkyl; or R1 and R2 together form a 5 to 7-membered heterocyclic ring fused with the piperazine ring, which ring may be substituted with hydroxy; R3 is hydrogen, alkyl, alkenyl, cycloalkyl or cycloalkylalkyl; or R2 and R3 together form a 3 to 7-membered carbocyclic ring which is spiro-fused to the piperazine ring; and R4 is hydrogen or alkyl. The compounds of the invention have potent antagonist action on dopamine D1 receptors and are useful in the treatment of diseases of the central nervous system, such as psychoses, schizophrenia (positive as well as negative symptoms), anxiety, depression, sleep disturbances, migraine, Parkinson's disease or cocaine abuse.
Patent NZ-272876-A (NZ)
Title: Screen conveyor for harvester; comprises at least one adjuster which can be shifted into position against the conveyor belt so as to form a step
Inventor: KALVERKAMP KLEMENS
IPC: A01D17/10
Filed: 1995-08-28
Abstract: The lifted root crop is passed up a conveyor with the belt formed by crossbars between flexible side belts. The belt is looped between pairs of wheels running on the side belts with the upper wheels (12) adjustable in position to form steps between them and the fixed wheels (10) under the belt. These steps cause the crop to be shaken and rotated as it passes through the steps thereby removing any soil.   The adjustable rollers are on adjustable support arms and can be adjusted progressively. This allows the operator to select the optimum step height to suit the conditions. The wheels have profiled outer rims to grip the belt. Suitable profiles include polygonal sided wheel discs.
Patent NZ-290236-A (NZ)
Title: Inhibition ofleucotriene biosynthesis and pharmaceutical compositions comprising aryl-urea derivatives
Inventor: CROOKS STEPHEN LAWRENCE
IPC: A61P35/00
Filed: 1995-07-14
Abstract: A method of inhibiting leukotriene biosynthesis, involving administering a compound of formula (I) wherein M, R, R', R'', and n are as defined herein. Also, a pharmaceutical composition involving such a compound and the use of such compounds in the manufacture of a pharmaceutical composition for inhibiting leukotriene biosynthesis.
Patent NZ-308130-A (NZ)
Title: Gas lighter has safety device in the form of a knurled wheel moved by a smooth surfaced carrier
Inventor: FRIGIERE RENE
IPC: F23Q2/46
Filed: 1996-04-26
Abstract: The gas lighter comprises a reservoir intended to contain a liquid petroleum gas, a valve mounted on the resevoir to let the gas out, a system (3) for opening and closing the gas flow as well as a lighting system presenting a flint cooperating with a wheel (6) rotationally driven by at least one driver (9) mounted coaxially with the wheel (6). According to the invention, the peripheral surface of each driver (9), intended to come into contact with a user's finger, is smooth. Such a lighter is easy to use for an adult, but difficult for a child. Furthermore, it has only few modifications with respect to a standard lighter.
Patent NZ-320468-A (NZ)
Title: Fluid control valve and a blower, the valve including a member rotatable to a position in which both blower inlet and outlet ports are closed
Inventor: HAYEK ZAMIR
IPC: F16K11/085
Filed: 1996-10-30
Abstract: A fluid control valve for connection between a positive fluid pressure source, a negative fluid pressure source and a device to be connected alternately to the pressure sources, comprising a body having ports for connection to the fluid pressure sources and the device, and a rotary member rotatable with respect to the body and adapted selectively to interconnect the ports, whereby the rotary member is operable on rotation in a single sense to connect alternately the positive fluid pressure source and the negative fluid pressure source to the device.
Patent NZ-328900-A (NZ)
Title: Substituted phenyl or pyridyl substituted phenyl, benzo[b]furan or indolyl derivatives and medicaments
Inventor: DHAINAUT ALAIN
IPC: C07D209/08
Filed: 1997-10-03
Abstract: Substituted biphenyl and phenyl pyridyl derivatives of formula (I), their isomers and their salts are new. R1 = 3-7C cycloalkyl, phenyl, naphthyl, optionally unsaturated mono- or bicyclic heterocycle having 1-3 O, S or N, 1-6C alkyl or 1-6C alkenyl (sic) (all optionally substituted); A = a bond (provided that R1 is other than C1 or C2 alkyl) or O, S, -CO-, -C(=N-ORc)- or -CH(ORc)-; Rc = H, 1-6C alkyl or 3-7C cycloalkyl; R2 = 1-6C alkyl, 1-6C alkenyl (sic), 1-6C alkynyl (sic) or 3-7C cycloalkyl (all optionally substituted) halo, formyl, carboxy, 1-6C alkylcarbonyl, 3-7C cycloalkylcarbonyl, 1-6C alkoxycarbonyl, 3-7C cycloalkoxycarbonyl, carbamoyl (optionally substituted), amino (optionally substituted by one or two 1-6C alkyl, 1-6C acyl, 3-7C cycloalkyl or forming with the N atom which bears them a 5-7 membered heterocycle containing 1-3 O, N or S (sic)), formamido, CN, amidino (optionally substituted), hydroxyaminomethyl (optionally substituted), amide-oxime (optionally substituted), hydrazono (optionally substituted), -C(R21)=N-O-R22 or -C(R21)=N(O)-R23; R21 = H, 1-6C alkyl or 3-7C cycloalkyl; R22 = H, 1-6C alkyl, 3-7C cycloalkyl or 1-6C acyl; R23 = 1-6C alkyl or 3-7C cycloalkyl; R3 = H, 1-6C alkyl, 3-7C cycloalkyl or 1-6C acyl or =C(R2)-C(X-R3)= forms an unsaturated 5-membered heterocyclic ring of formula (i); X = O, S or NR"; R" = H, 1-6C alkyl, 3-7C cycloalkyl or 1-6C acyl; ring B is phenyl or pyridyl; Ra, Rb = H, halo, 1-6C alkyl, OH, 1-6C alkoxy, carboxy, 1-6C polyhaloalkyl, CN, NO2, 1-6C alkoxycarbonyl, 3-7C cycloalkoxy carbonyl, amino (optionally substituted), carbamoyl (optionally substituted); provided that when A is a bond or O, B is phenyl, R1 is 3-7C cycloalkyl, phenyl or naphthyl (all optionally substituted), X is O, NH or amino(1-6C alkyl) and R3 is H or 1-6C alkyl, then R2 is not carboxy.
Patent NZ-332256-A (NZ)
Title: Glial cell line-derived neurotrophic factor (GDNF) receptors and nucleic and amino acid sequences encoding them
Inventor: FOX GARY M
IPC: A61P25/28
Filed: 1997-04-15
Abstract: Disclosed are glial cell line-derived neurotrophic factor (GDNF), a potent neurotrophin that exhibits a broad spectrum of biological activities on a variety of cell types from both the central and peripheral nervous systems. This involves the cloning and characterization of a high affinity receptor for GDNF. This molecule has been named GDNF receptor (GDNFR) since it is the first known component of a receptor system. Nucleic acid and amino acid sequences are described for GDNFR protein products. A hydrophobic domain with the features of a signal peptide is found at the amino terminus, while a second hydrophobic domain at the carboxy terminus is involved in the linkage of the receptor to the cell membrane. The lack of a transmembrane domain and cytoplasmic region indicates that GDNFR requires one or more accessory molecules in order to mediate transmembrane signaling. GDNFR mRNA is widely distributed in both nervous system and non-neural tissues, consistent with the similar distribution found for GDNF.
Patent NZ-337934-A (NZ)
Title: Induction -heating element pole pieces cast into tabletop
Inventor: ESKILDSEN CHRISTIAN
IPC: A47B96/18
Filed: 1998-03-13
Abstract: A tabletop 1 includes integral induction-heating elements fitted into the lower side of the tabletop.  The pole pieces 5, 6 of the heater are formed of a material containing ferromagnetic particles and are cast into the lower side of the tabletop to constitute a magnetic coupling between the cooking utensil on the top surface of the tabletop and the induction-heating element 3, 4.
Patent NZ-500567-A (NZ)
Title: Stabilised liquid enzyme preparation and the use thereof
Inventor: BRAGULLA SIEGFRIED
IPC: C11D3/00
Filed: 1998-04-15
Abstract: A liquid stabilized enzyme preparation comprises a cleaning active enzyme, a solvent and a basic nitrogen compound as a stabilizer. The solvent is selected from ethylene glycol, propylene glycol, glycerol and mixtures thereof. The basic nitrogen compound is selected from the group of polyhexamethylene biguanide, N,N-bis-(3-aminopropyl)-dodecyl amine, salts thereof and mixtures of these compounds. Dairy equipment can be cleaned using a cleaning solution prepared by diluting the stabilized enzyme preparation (described above) with water in a ratio of 1:5000 to 1:500 then adding 0.01 to 0.2% by weight, based on the cleaning solution as a whole, of a buffer concentrate for adjusting a pH value to about 9.5.
Patent NZ-506033-A (NZ)
Title: Nucleoside analogues useful for the inhibition of HBV and retroviruses
Inventor: WAHLING HORST
IPC: C07D473/00
Filed: 1999-02-12
Abstract: A compound of formula 1 and pharmaceutically acceptable salts are disclosed, wherein R is independently H or -CH3. These compounds are useful in the treatment of retroviruses such as HIV, and HBV. Pharmaceutical compositions containing this compound may also include additional antiviral compounds.
Patent NZ-506671-A (NZ)
Title: Detection of fermentation-related microorganisms
Inventor: ENGEL STACIA R
IPC: C12Q1/6895
Filed: 1999-03-11
Abstract: DNA  sequences  are  disclosed  which  are  useful  in identifying  different fermentation-related  microorganisms, such   as   those  involved  in  fermentations.  These   DNA sequences can be used to provide oligonucleotide primers  in PCR  based  analysis for the identification of fermentation- related  microorganisms.  The  DNA  sequences  include   the internal transcribed spacer (ITS) of the ribosomal RNA  gene regions  of  particular fermentation-related microorganisms, as  well  as oligonucleotide primers which are derived  from these   regions   which  are  capable  of  identifying   the particular microorganism.
Patent NZ-507221-A (NZ)
Title: Antitumor agent
Inventor: MORINAGA YOSHIHIRO
IPC: A61K33/243
Filed: 1999-03-29
Abstract: An antitumor agent comprising a stilbene derivative or a salt, ester or solvate thereof, and a platinum coordination compound.  The agent may optionally contain one or more pharmaceutically acceptable carriers, diluents or other substances required for the pharmaceutical preparation.
Patent NZ-510464-A (NZ)
Title: Further pro polypeptides and sequences thereof
Inventor: BAKER KEVIN
IPC: C12N15/12
Filed: 1999-09-01
Abstract: An isolated nucleic acid has at least 80% sequence identity to a nucleotide sequence that encodes a polypeptide comprising the amino acid sequence shown in Figure 32(SEQ IDNO:54). Preferably the nucleotide sequence is that shown in Figure 31 (SEQ ID NO:53) or that deposited under ATCC 203287. Also described are vectors, host cells and antibodies associated with the nucleic acids and polypeptides. The polypeptide can be used in the manufacture of a pharmaceutical for treating a tumor.
Patent NZ-514753-A (NZ)
Title: Silica-based sols
Inventor: PERSSON MICHAEL
IPC: D21H17/68
Filed: 2000-04-28
Abstract: An aqueous sol containing silica-based particles which has an S-value within the range of from 10 to 45 %, a viscosity within the range of from 5 to 40 cP, and a molar ratio of SiO2 to M2O. M is alkali metal or ammonium, within the range of from 10:1 to 40:1.
Patent NZ-515224-A (NZ)
Title: A method and apparatus for forming an article and article formed thereby
Inventor: LEWIS PETER JOSEPH LELIEVRE
IPC: B29C43/52
Filed: 2001-11-02
Abstract: A method and moulding apparatus for forming an article from a stock material containing a sufficient amount of thermoplastics material to bind the material together when formed. The method comprises the steps of: compressing the material and retaining it within a container; transferring the container to a heating apparatus; supplying sufficient energy to melt sufficient thermoplastics material substantially throughout the stock material to bind the stock material together when cooled; and releasing the article produced from the container. The apparatus includes: a chamber (30) adapted to accommodate a perforated container (26) containing material to be formed; a plurality of tubes (33) movable relative to the chamber from a rest position in which the tubes are outside of a region for accommodating a container to an operating position in which the tubes are introduced into the region for accommodating the container such that, in use, they pass through perforations in a container to enable steam to be delivered substantially throughout the container; and a steam source for supplying superheated steam to the tubes.
Patent NZ-515519-A (NZ)
Title: Posts
Inventor: DUNCAN ERNEST JOHN
IPC: A01G17/06
Filed: 2001-11-19
Abstract: A post (10), comprising of a first elongated component (11) having a first side wall (not shown) forming a partially enclosed first hollow, the edges of said first side wall or respective portions of said first side wall adjacent to the edges defining a first elongate opening (not shown) extending along its length.  Also a second elongate component (12) having a second side wall (not shown) forming a partially enclosed second hollow, the edges of said second side wall or respective portions of said second side wall adjacent to the edges defining a second elongate opening (25b) extending along its length.  The said elongate component being engaged with said first elongate component with said second opening being within said first hollow and the edges of said first side wall or respective portions of said first side wall adjacent the edges engaging with the outer face of said second wall to secure said second component to said first component.
Patent NZ-516859-A (NZ)
Title: Gaming machine with increased large prizes
Inventor: BRYANT NATALIE
IPC: A63F1/00
Filed: 2000-09-08
Abstract: A gaming machine (10) includes a plurality of display positions (14, 16) for displaying combinations of symbols of a game. A controller controls operation of the machine (10). The controller includes a random number selector for selecting the symbols to be displayed at each display position (14, 16). The chance of a particular symbol (42) appearing at a predetermined display position (14, 16) is dependent on whether or not that particular symbol has been selected to appear at least one display position.
Patent NZ-521939-A (NZ)
Title: Inducing an immune response to amyloid beta peptides and amyloid deposits using a synthetic non-amylogenic but immunogenic peptide
Inventor: FRANGIONE BLAS
IPC: C07K19/00
Filed: 2001-05-22
Abstract: Described are synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid â, which can be used alone or conjugated to an immunostimulatory molecule in an immunizing composition for inducing an immune response to amyloid â peptides and amyloid deposits. The graph shows the results of a thioflavin T fluorometric assay. Fibril formation of Aâ1-42, Aâ l-30-NH2, and K6Aâl-30-NH2 was measured in vitro following incubation at 37° C. K6Aâl-30-NH2 was the only peptide that did not form fibrils at any of the time points.
Patent NZ-522381-A (NZ)
Title: Pharmaceutical form of administration for peptides, methods for its production and use
Inventor: BAUER HORST
IPC: A61P13/08
Filed: 2001-05-16
Abstract: The application discloses a pharmaceutical form of administration suitable for parenteral administration, which comprises the following: 1. One or more peptides prone to aggregation in dissolved or dispersed form, each peptide being in the form of its acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salt 2. One of the above acids as free acid 3. Further additives and excipients (if appropriate) from the class consisting of the acids, surface-active substances, polymers, lipids or sugars. The processes for the production of a pharmaceutical form of administration are also disclosed in the specification along with the use of the pharmaceutical form of administration. The use described is the preparation of a medicament for parenteral administration in sex hormone-dependent benign and malignant diseases.
Patent NZ-525032-A (NZ)
Title: Flexible container having flat walls
Inventor: BUCHANAN JERRY E
IPC: B31B50/64
Filed: 2001-08-28
Abstract: A flexible container (10) has a base (12) that includes a bottom (20), side walls (22, 24, 26, 28) and an interior (30), the bottom defining a substantially flat planar surface when the container houses product and the container rests thereon, an upper panel portion (14), that is adapted to be received within the interior of the base portion and includes side panels that define a closure member (60, 62). The upper panel is constructed and arranged to define a substantially flat surface when the closure member is closed and portions of the upper panel are folded over. The upper panel includes a portion that is sealed to the base portion. A pair of handles (16, 18) may be secured to the base portion. The flat top and flat bottom allow for vertical stacking of the filled containers. The container may be manufactured from a flat sheet of plastic material having a width substantially equal to a length of the base portion, by indexing the flat sheet in intervals equal to a width or more of the base portion; bonding handles at one end to the sheet; applying closure means to a free end of each of the pair of panels; and forming the flat sheet, panels and pair of handles into the flexible container.
Patent NZ-528559-A (NZ)
Title: Oxabispidine compounds in delayed and sustained release pharmaceutical compositions
Inventor: CARLSSON HANS
IPC: A61K31/5386
Filed: 2002-04-12
Abstract: A modified release pharmaceutical composition comprises as an active ingredient, 4-({3-7-(3,3-dimethyl-2-oxobutyl)- 9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]propyl}amino)benzonitrile, tert-butyl 2-{7-[3-(4-cyano-anilo)propyl]-9-oxa-3,7- diazabicyclo[3.3.1]non-3-yl} ethylcarbamate, tert-butyl 2-{7-[4-(4-cyanophenyl)butyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3- yl} ethylcarbamate, or tert-butyl 2-{7-[(2S)-3-(4-cyanophenoxyl)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl} ethylcarbamate. Preferably the composition is adapted to provide delayed and/or sustained release of active ingredients. The composition can be use din the manufacture of a medicament for the prophylaxis or the treatment of an arrhythmia, such as a ventricular arrhythmia, atrial fibrillation or artial flutter.
Patent NZ-536659-A (NZ)
Title: Compositions comprising organic disulfides, cysteine sulfoxides, sulfones, sulfoximines or other sulfur containing substances and their use in therapy in combination with radiation
Inventor: HOLT JOHN ALFRED GORTON
IPC: A61K31/195
Filed: 2004-11-18
Abstract: The disclosure provides therapies for treating a range of conditions, including cancer, enhancing T-cell count, or reducing the concentration of pathogenic particles (e.g. virus or prion particles) - most especially those selected from human immunodeficiency virus (HIV), bovine spongiform encephalopathy (BSE) agent, scrapie agent, hepatitis agent, disseminated ("multiple") sclerosis agent, Creutzfeld Jacob disease (CJD) agent, variant CJD agent, systemic lupus erythematosis (SLE) agent, ankylosing spondylitis agent and amyotrophic sclerosis agent futhermore amyloid conditions, Alzheimer's disease, and non-malignant diseases - applicable in vivo to a patient in need of such treatment, the therapies comprising administering to the patient an effective amount of defined active agents, and, while the agents are present, administering to the patient an effective dose of electromagnetic radiation of frequency in the range of about 400-450 MHz, wherein the active agent comprises organic disulfides (such as a penicillamine disulfide), cysteine sulfoxides, sulfones, sulfoximines or other sulfur containing substances as defined in the specification.
Patent NZ-541878-A (NZ)
Title: Derivatives of seleno-amino acids with improved bioavailability and method for assuring adequate dietary requirements of selenium for livestock
Inventor: ABDEL-MONEM MAHMOUD M
IPC: A23K1/16
Filed: 2003-12-10
Abstract: Metal L-seleno-alpha-amino acid 1:1 complex salts and their use as a bioavailable feed ration supplement for domesticated animals such as cattle, pigs and poultry are disclosed, wherein the metal may be selected from the group consisting of zinc, manganese, copper, cobalt, iron and chromium and wherein the seleno-amino acid may be L-selenomethionine or Se-methyl-L-selenocysteine. These metal L-seleno-alpha-amino acid complex salts are used as a source of selenium in animal nutrition.
Patent NZ-543478-A (NZ)
Title: Apparatus and method for the treatment of waste
Inventor: AMES ROY VICTOR
IPC: C02F1/44
Filed: 2004-04-16
Abstract: A waste treatment system is disclosed which is suitable for domestic use and capable of producing water suitable for recycling within the household. The system includes a bioreactor (30) and a decomposition chamber (16). The bioreactor (30) is adapted to digest liquid-base waste material using bacteria and is operable under anaerobic, anoxic and/or aerobic conditions. The decomposition chamber (16) decomposes substantially solid waste generated in the bioreactor. The bioreactor and decomposition chamber are in fluid communication such that substantially solid waste material generated in the bioreactor can be transferred to the decomposition chamber for further treatment. Resulting solids may optionally be forwarded to a vegetation cell (24) and the liquid (34) leaving the bioreactor may be optionally passed to a membrane treatment unit (40) and a disinfection unit (50).
Patent NZ-543554-A (NZ)
Title: Quinoline derivatives as phosphodiesterase inhibitors
Inventor: BALDWIN IAN ROBERT
IPC: C07D413/14
Filed: 2004-05-19
Abstract: Disclosed is a quinoline derivative of formula (I) or a pharmaceutically acceptable salt thereof wherein the substituents are disclosed within the specification. Also disclosed is the suitability of the above compound of formula (I) for use in the treatment of inflammatory and/or allergic diseases or for the prophylaxis or treatment of a clinical condition for which a selective phophodiesterase type IV (PDE4) inhibitor is indicated.
Patent NZ-543580-A (NZ)
Title: Footwear molds with location mark for heel strap rivet
Inventor: SEAMANS SCOTT
IPC: A43B7/08
Filed: 2004-05-14
Abstract: Dislcosed are apparatus and methods for manufacturing footwear pieces. In various cases, the apparatus includes a footwear form (1260) that includes a location mark corresponding to a location of a strap rivet. The footwear form is an inner portion of a footwear mold, and the footwear mold is comprised of an upper portion (1210) and a lower portion (1220) that substantially encompass the footwear form.