baber/WOPTO huggingface dataset:
Patent EP-3530321-A1 (EP)
Inventor: TRAPANI JOSEPH
IPC: A61K39/44
Filed: 2005-12-12
Abstract: In a first aspect the present invention provides a method for producing an adoptive immune response to a target cell in a subject, said method including the steps of engineering a CD4+ T cell and engineering a CD8+ T cell to express a molecule capable of binding to an antigen on the target cell, and administering an effective number of the engineered CD4+ and CD8+ T cells to the subject. According to this method the CD4+ T cell and the CD8+ T cell are obtained from the subject, engineered, and re-administered to the subject to produce the adoptive immune response Applicants have found that in adoptive transfer experiments in vivo, administration of sufficient numbers of antigen engineered CD4+ in combination with engineered CD8+ cells leads to a significantly enhanced immune response to a target cell. It is demonstrated herein that the injection of CD4+ and CD8+ T cells engineered to express a molecule capable of binding to a tumor associated antigen led to significant improvement in survival of subjects having established lung metastases, compared with transfer of unfractionated spleen-derived (largely CD8+) engineered T cells. Importantly, anti-tumor responses in the subjects correlated with persistence and localization of engineered T cells at the tumor site and in the blood and spleen. Applicants have further demonstrated herein that subjects treated with engineered CD4+ and CD8+ T cells that survived primary tumor challenge could reject a subsequent rechallenge with the same tumor. The studies disclosed herein demonstrate the therapeutic advantage in the combined transfer of antigen-specific gene-modified CD4+ and CD8+ T cells to significantly enhance T cell adoptive strategies for the treatment conditions such as cancer and infectious diseases.
Patent EP-3517695-A1 (EP)
Inventor: SANTOS PEREIRA BRUNO
IPC: E03D1/26
Filed: 2019-01-15
Abstract: An adaptation kit (1) for flushing valves of flush tanks, in particular ceramic flush tanks, comprising a support (4), extending along an axis (A) and shaped so as to receive and support a flushing valve (2), and a set of two or more adapter elements (5A, 5B), having respective drain portions (40A, 40B) different from one another, shaped to be joined to respective different flush tanks, and respective fastening members (6) for selectively fastening one of the adapter elements (5A, 5B) to the support (4) so that they are interchangeable on the support (4).
Patent EP-3543587-A1 (EP)
Inventor: BRIGNANI ROBERTO
IPC: F16M11/08
Filed: 2019-01-29
Abstract: A wearable support for electronic devices (100), particularly for portable electronic devices, the support (100) comprising: 
- A support area (101) adapted to removably retain an electronic device (200) in a fixed position; 
- At least one first spacer element (102a) that is movably joined to the support area (101); 
- At least one flexible tie-rod (103), which is retained between a first point (103a) and a second point (103b), respectively at said at least one first spacer element (102a) and at the support area (101); 
- An adjustable tensioner (104) for said at least one flexible tie-rod (103), comprising at least a first configuration for use, in which it exerts a first and greater pulling force on the flexible tie-rod (103), thus locking the position assumed by said at least one first spacer element (102a) with respect to the support area (101), and a second configuration for use, in which it exerts a second and lesser pulling force on the flexible tie-rod (103), determining a freedom of movement of said at least first element
Patent EP-3696206-A1 (EP)
Title: Schäumbare, dämmschichtbildende mehrkomponenten-zusammensetzung und deren verwendung
Inventor: PAETOW MARIO
IPC: C08G18/73
Filed: 2019-02-12
Abstract: Die vorliegende Erfindung betrifft eine schäumbare, dämmschichtbildende Mehrkomponenten-Zusammensetzung auf Polyharnstoffbasis und/oder Polyurethanbasis und deren Verwendung zum Ausschäumen von Öffnungen, Kabel- und Rohrdurchführungen und Fugen zum Zwecke des Brandschutzes.
Patent EP-3623324-A1 (EP)
Inventor: NAKAMOTO HIDEICHI
IPC: B25J15/08
Filed: 2019-02-27
Abstract: A conveyance apparatus includes a camera, a grip, an arm, a database, and a processor. The processor is configured to determine which grasping mode of frictional grasping, suction grasping and back face grasping should be selected from the image information photographed by the camera and the information in the database. The processor is configured to move the arm and the grip based on the determination, and take out the one or more packages from the placement portion by moving the arm and the grip while at least one of the one or more packages is grasped by the grip.
Patent EP-3572937-A1 (EP)
Inventor: BENNETT STEVEN
IPC: G06F9/455
Filed: 2006-01-10
Abstract: A processor including a virtualization system of the processor with a memory virtualization support system to map a reference to guest-physical memory made by guest software executable on a virtual machine which in turn is executable on a host machine in which the processor is operable to a reference to host-physical memory of the host machine.
Patent EP-3536689-A1 (EP)
Inventor: KILBURN JOHN PAUL
IPC: A61K31/5375
Filed: 2013-10-11
Abstract: The present invention is directed to novel cyclic amines which inhibit the P2X 7  receptor.
Patent EP-3711848-A1 (EP)
Inventor: WILM MATTHIAS
IPC: B01J13/02
Filed: 2019-03-20
Abstract: The present invention provides a simplified method which can provide well-defined bioactive lipid membranes, which in particular have large dimensions and which are flat The present invention relates to a method for preparation of a bioactive lipid membrane, comprising the following steps: a) Applying first lipid molecules (1) to form a first lipid layer (17) on a liquid surface (14) by electro-spraying, b) applying a mixture of second lipid molecules (2) and protein molecules (19) by electro-spraying so as to form a functionalized lipid bi-layer membrane having protein molecules integrated therein, and c) applying a second hydrophilic layer (20) to the lipid bi-layer membrane formed in step b). Further, it is provided a functionalized lipid bi-layer membrane.
Patent EP-3718769-A1 (EP)
Inventor: DR GIER ANDREAS
IPC: B32B27/18
Filed: 2019-04-02
Abstract: Die vorliegende Erfindung betrifft eine Holzwerkstoffplatte mit antistatischen Eigenschaften umfassend mindestens eine Trägerplatte (1) und mindestens einer auf mindestens einer Seite der Trägerplatte angeordnete Harzschicht (2), wobei die mindestens eine Harzschicht (2) kohlenstoffbasierte Partikel, insbesondere Kohlenstoffnanoröhren (CNT) oder Graphen, mindestens eine Verbindung mit der allgemeinen Formel (I)R<sup>1</sup><sub>a</sub>R<sup>2</sup><sub>b</sub>SiX<sub>(4-a-b)</sub>(I),und/oder deren Hydrolyseprodukte, wobei X H, OH oder ein hydrolysierbarer Rest ausgewählt aus der Gruppe umfassend Halogen, Alkoxy, Carboxy, Amino, Monoalkylamino oder Dialkylamino, Aryloxy, Acyloxy, Alkylcarbonyl ist, R<sup>1</sup>ein organischer Rest ist ausgewählt aus der Gruppe umfassend Alkyl, Aryl, Cycloalkyl, die durch -O- oder -NH- unterbrochen sein können, wobei R<sup>1</sup>mindestens eine funktionelle Gruppe Q<sub>1</sub>aufweist, die ausgewählt ist aus einer Gruppe enthaltend eine Hydroxy-, Amino-, Monoalkylamino-, Carboxy-, Mercapto-, Alkoxy-, Aldehyd-, Acryl-, Acryloxy-, Methacryl-, Methacryloxy-, Cyano-, Isocyano- und Epoxid- Gruppe, R<sup>2</sup>ein nicht-hydrolysierbarer organischer Rest R<sup>2</sup>ist ausgewählt aus der Gruppe umfassend Alkyl, Aryl, Alkenyl, Alkinyl, Cycloalkyl, Cycloalkenyl; a = 0, 1, 2, 3, insbesondere 1 oder 2 ist, und b = 1, 2, 3, oder 4 ist, insbesondere 0 oder 1 ist, umfasst.
Patent EP-3549466-A1 (EP)
Inventor: BECK LOUIS SAMUEL
IPC: A41D27/28
Filed: 2019-04-05
Abstract: The present invention concerns a ventilation element (10) for an article of apparel, footwear, or a sports accessory (25), comprising: a first surface (11), comprising a foam; a second surface (12); wherein the first surface (11) and the second surface (12) are spaced apart, creating a void, so that air may circulate between the first surface (11) and the second surface (12).
Patent EP-3553403-A1 (EP)
Title: Hvac-system und verfahren zum betreiben eines hvac-systems
Inventor: PRADIPTA JUSTIN
IPC: F24F140/50
Filed: 2019-04-09
Abstract: Die vorliegende Offenbarung betrifft ein Verfahren zum Betreiben eines HVAC-Systems. Das HVAC-System kann wenigstens ein Bedarfssubsystem in Signalkommunikation mit einer Versorgungsseite einschließen. Das Verfahren kann einen Schritt des Bestimmens eines Bedarfs (Q) mit einer Bedarfsschätzfunktion einschließen. Die Bestimmung kann von einem Bedarfsseitenprozessor ausgeführt werden. Der variable Eingang der Bedarfsfunktion kann eine Zoneneigenschaft und ein Steuersignal (U) umfassen. Das Verfahren kann Kommunizieren des Bedarfs (Q) vom Bedarfssubsystem zur Versorgungsseite einschließen. Das Verfahren kann Bestimmen einer Versorgungsseitenbetriebsleistung als Funktion des Bedarfs (Q) und von Versorgungsseitenparametern einschließen; wobei die Bestimmung von einem in der Versorgungsseite eingeschlossenen Versorgungsseitenprozessor ausgeführt wird. Die vorliegende Offenbarung betrifft auch das Bedarfssubsystem, die Versorgungsseite und das HVAC-Subsystem, dazu konfiguriert, das erfindungsgemäße Verfahren auszuführen.
Patent EP-3557951-A1 (EP)
Inventor: KIM BYUNG JUN
IPC: G03B15/05
Filed: 2019-04-17
Abstract: Provided is a camera using a light source having a subject eye protection function. The camera includes a light source driver installed between a power supply and a light source for emitting light to a subject and configured to convert electric power supplied by the power supply to a pulse current, a light source driver controller configured to control the light source driver to be turned on or off such that the light source driver converts the electric power supplied by the power supply to the pulse current, a current measurement unit configured to measure the pulse current supplied to the light source, an amplitude controller configured to control an amplitude of the pulse current measured by the current measurement unit, a smoothing circuit configured to smooth the pulse current of which the amplitude is controlled by the amplitude controller, and a comparator controller configured to control the electric power supplied by the power supply to be interrupted in a case in which the smooth current smoothed by the smoothing circuit is greater than a preset threshold value.
Patent EP-3725158-A1 (EP)
Title: Clipping machine with secured access to the clipping region
Inventor: WEIDENHAUS BJÖRN
IPC: A22C11/12
Filed: 2019-04-18
Abstract: The present invention relates to a clipping machine (CM) for producing sausage-shaped products, like sausages, containing a flowable filling material in a tubular or bag-shaped packaging casing (M), the machine (CM) comprising filling means (10) configured to feed filling material into the casing (M), and further comprises closing means (20) arranged downstream the filling means (10), for closing the casing (M) in a closing region (CR). A housing (H) is provided, enclosing at least the closing region (CR), comprising at least a front wall (50) and a first side wall (70), wherein the front wall (50) is arranged at least substantially parallel to a longitudinally extending axis (A) of the filling means (10), and further comprises an opening (56) which can be closed by a movable door element (52), movable between an open position, allowing access to the closing region (CR) and a closed position, covering and blocking access to the closing region (CR). The side wall (70) faces the filling means (10) and further comprises a movable housing element (72), movable between at least an open position and a closed position, wherein the movable housing element (72) comprises an opening (74) for passing through the sausage-shaped products, and wherein the movable housing element (72) enables access from a side of the first side wall (70) to the closing region (CR) when in the open position; and wherein the movable housing element (72) covers and blocks access to the closing region (CR) when in the closed position.
Patent EP-3667354-A1 (EP)
Title: Systems and methods for angle of arrival estimation
Inventor: FORT ANDREW
IPC: G01S3/02
Filed: 2019-05-10
Abstract: A method for operating a wireless receiver includes receiving wireless signals from a transmitter at a first antenna and a second antenna. The wireless signals include a signal carrier and one or more data symbols modulated onto the signal carrier. The one or more data symbols in the wireless signal are decoded to determine a symbol phase contribution. The phase of the wireless signals at the first antenna and the second antenna during one or more symbol periods is estimated to provide a first set of phase measurements and a second set of phase measurements, respectively. The symbol phase contribution is removed from the first set of phase measurements and the second set of phase measurements to provide a first corrected set of phase measurements and a second corrected set of phase measurements, respectively, which are used to estimate an angle of arrival of the wireless signals.
Patent EP-3739106-A1 (EP)
Inventor: SCHULTZ JAKOB
IPC: D06F39/02
Filed: 2019-05-13
Abstract: The invention relates to a water-bearing household appliance (1), particularly a dishwasher or washing machine, with an automatic dosing system (30) for automatically dosing a detergent tablet (202) provided by a storage cartridge (200) for storing a plurality of detergent tablets (202) into washing liquor for washing dishes, comprising a receiving portion (32) for removably receiving the storage cartridge (200) and a driving unit (34) for actuating a dosing device (100) that is attachable to the storage cartridge (200) for dosing the detergent tablet (202), wherein the dosing device (100) comprising a scoop (120) and a plug (130), wherein the scoop (120) is configured to pick up a detergent tablet (202) from the storage cartridge (200), lift the detergent tablet (202) to an opening (124) in the scoop (120) and transport the detergent tablet (202) to a receiving chamber (132) formed in the plug (130) when the scoop (120) is turned in a first turning direction about a rotational axis (X) that is perpendicular to a gravitational vector (G), and the plug (130) is configured to release the detergent tablet (202) from the receiving chamber (132).
Patent EP-3588711-A1 (EP)
Title: Montagehilfe für eine unterputzdose, verfahren zum montieren und anordnung
Inventor: REUTHER HERBERT
IPC: H02G3/12
Filed: 2019-05-28
Abstract: Die Erfindung betrifft eine Montagehilfe (10; 60; 80) für eine Unterputzdose (20;70), wobei die Unterputzdose (20; 70) in einer Ausnehmung (40), insbesondere in Mauerwerk (42), anbringbar ist und wobei die Unterputzdose (20; 70) einen Innenraum zur Aufnahme von elektrischen Installationsgeräten ausbildet, wobei die Montagehilfe (10; 60; 80) einen Aufnahmebereich für Montageschaum (50) aufweist, wobei der Aufnahmebereich an einer äußeren, dem Innenraum abgewandten Bodenseite der Unterputzdose (20; 70) angeordnet ist und wobei der Aufnahmebereich so ausgebildet ist, dass der Montageschaum (50) sich vom Aufnahmebereich in die Ausnehmung (40) hinein ausbreiten kann, um die Unterputzdose (20; 70) in der Ausnehmung (40) zu fixieren.
Patent EP-3567995-A1 (EP)
Title: Cable management device
Inventor: CHEN KEN-CHING
IPC: H05K7/14
Filed: 2018-02-27
Abstract: A cable management device (38) includes a first cable management arm (40), a second cable management arm (42) and an auxiliary member (62). The second cable management arm (42) is movable relative to the first cable management arm (40). The auxiliary member (62) can be moved with respect to one of the first cable management arm (40) and the second cable management arm (42) from a first position to a second position, so as to increase a length of the cable management device (38).
Patent EP-3569235-A1 (EP)
Inventor: LOUTIT JEFFEREY S
IPC: A61K9/12
Filed: 2010-09-03
Abstract: The invention relates to methods for treating cystic fibrosis comprising administering to a human in need thereof an aerosol solution comprising levofloxacin or ofloxacin and a divalent or trivalent cation. The invention relates in particular to administering the aerosol solution to a human wherein said human has a pulmonary infection comprising P. aeruginosa.
Patent EP-3599055-A1 (EP)
Inventor: WU PI-LIANG
IPC: B25B25/00
Filed: 2019-06-19
Abstract: A remote operating tool capable of replacing work units contains: a control unit (1), a connection assembly (2), and a work unit (3). The control unit includes a first plier part (11), a second plier part (12), and a fixing shaft (13). The first plier part has a first grip portion (112) and a limitation extension (114), the second plier part has a second grip portion (122) and an accommodation extension (124), and the accommodation extension has an aperture (126). The connection assembly includes a cable (21) and an accommodation sleeve (22), the cable has a knob (23), and the accommodation sleeve has a fitting member (24), wherein the fitting member has a large-diameter section and (242) a small-diameter section (244). The limitation extension has a first cutout (118), and the accommodation extension has a second cutout (128). The control unit further includes a stopper, wherein the defining member (4) is a shell and includes a first chamber.
Patent EP-3608104-A1 (EP)
Title: Verfahren zum rechnergestützten versorgen eines verbundes von mehreren maschinen der grafischen industrie mit jeweiligen digitalen produktionsaufträgen
Inventor: FISCHER JÖRG-ACHIM
IPC: B41F33/16
Filed: 2019-07-02
Abstract: Die Erfindung betrifft ein Verfahren zum rechnergestützten Versorgen eines Verbundes (1) von mehreren Maschinen (2a bis 2n) der grafischen Industrie mit jeweiligen digitalen Produktionsaufträgen (12a bis 12m), wobei wenigstens eine Maschine (2b) im Falle einer sensorisch (6b) erfassten Störung diese Maschine (2b) in einem digitalen Rechner (3) in einen eingeschränkten Zustand (10) versetzt wird und der Rechner (3) wenigstens einen digitalen Produktionsauftrag (12a bis 12m) für die Maschine (2b) unter Berücksichtigung der Störung auswählt und die Maschine (2b) im eingeschränkten Zustand (10) mit dem ausgewählten Produktionsauftrag (12a bis 12m) versorgt. Die Erfindung ermöglicht es mit Vorteil, die Gesamtproduktivität eines Verbundes aus mehreren Maschinen der grafischen Industrie, insbesondere Druckmaschinen, im Falle von Störungen an einzelnen Maschinen zu erhalten oder gar zu verbessern.
Patent EP-3593626-A1 (EP)
Inventor: ANAPARTI PHANI
IPC: A01F15/07
Filed: 2019-07-09
Abstract: A baler for use with a netwrap roll (46, 46a, 46b), where the baler includes a frame (30) supported on one or more wheels (34), a housing (38, 38') coupled to the frame (30) and at least partially defining a baling chamber therein, a netwrap assembly having a netwrap frame (86) coupled to the housing (38, 38') and at least partially defining a netwrap chamber (94), and a loading device at least partially positioned within the netwrap chamber (94). Where the loading device includes a first frame (126, 126') fixed relative to the netwrap frame (86), a second frame (130, 130') movable relative to the first frame (126, 126') between a frame stowed position and a frame deployed position, and a carriage (134) movable relative to the second frame (130, 130') between a carriage stowed position and a carriage deployed position, and wherein the carriage (134) is configured to support the netwrap roll (46, 46a, 46b).
Patent EP-3617228-A1 (EP)
Title: Antibody against aspergillus
Inventor: THORNTON CHRISTOPHER
IPC: G01N33/569
Filed: 2010-01-18
Abstract: The invention relates to antibodies to  Aspergillus  species and to methods of producing those antibodies. The invention also relates to the use of such antibodies in identifying the presence of the  Aspergillus  species and to methods of treating an infection with the  Aspergillus  species.
Patent EP-3573421-A1 (EP)
Inventor: ANDERSON NICHOLAS WILLIAM
IPC: H04W76/28
Filed: 2011-11-11
Abstract: A wireless network, such as an LTE ("Long-Term Evolution") network, may be configured to monitor a communications interface to set an inactivity timer that, in turn, sets the operating mode of a communications interface. The operating mode may comprise a time-domain reception pattern of the wireless device. A wireless device may monitor a communications interface that includes at least a first logical channel (for example for a first application) and a second logical channel (for example for a second application). Based on monitoring the communications interface, a first activity state for the first logical channel may be determined. Also, based on monitoring the communications interface, a second activity state (e.g., an activity status) for the second logical channel may be determined. An inactivity timer used by the communications interface may be set to a first value or a second value based on the first and second activity states. The battery life of a wireless device may be preserved by setting an inactivity timer responsive to the manner in which the wireless device is being used.
Patent EP-3605843-A1 (EP)
Title: Rc oscillator with comparator offset compensation
Inventor: GAUTAM BODH RAJ
IPC: H03K3/03
Filed: 2019-07-18
Abstract: A comparator-based oscillator generates an output frequency that is relatively independent of comparator offset voltages. Charging/discharging circuitry controls the comparator input voltage, and logic circuitry generates the oscillator output (e.g., clock) signal and controls the charging/discharging circuitry. During an oscillator charging cycle, the charging/discharging circuitry drives the voltage at the comparator input node from a relatively low initial charging voltage level up to the comparator reference voltage. During an oscillator discharging cycle, the charging/discharging circuitry drives the voltage at the comparator input node from a relatively high initial discharging voltage level down to the comparator reference voltage. The initial charging and discharging voltage levels depend on the comparator reference voltage, such that a comparator offset voltage directly affects the initial charging and discharging voltage levels, thereby keeping the output frequency relatively unchanged.
Patent EP-3624533-A1 (EP)
Inventor: HUANG HUANG
IPC: H04W72/04
Filed: 2015-05-30
Abstract: Embodiments of the present invention disclose a communication method, including: performing, by a base station, beam scanning and alignment together with first user equipment in a first subframe, to determine a beam that is used for sending data in the first subframe, where a quantity of beams used for sending data is greater than or equal to 1; and when sending data to the first user equipment by using the beam, sending, by the base station, beam information of the beam used for sending data, where the beam information includes at least identification information of the beam and a synchronization signal, where the synchronization signal is used by second user equipment to synchronize with the base station, and the identification information of the beam is used by the first user equipment and the second user equipment to identify the beam sent by the base station. The embodiments of the present invention further disclose a base station and user equipment. According to the present invention, a time for scanning and alignment can be reduced, so as to facilitate quick access of a user that is to perform access.