baber/WOPTO huggingface dataset:
Patent DE-68913618-D1 (DE)
Inventor: ROQUES BERNARD PIERRE
IPC: C07F9/40
Filed: 1989-07-28
Granted: 1994-04-14
Abstract: These compounds are represented by formula (I), in which each of R1 and R2=H, C1-C8 alkyl, C3-C7 cycloalkyl, or aromatic; (when R1=H, R2 can be an amine function-protecting radical, amino acid residue or peptide fragment; R1 and R2 being capable of forming, with N, a 5-7 component ring); A=carbonyl or methylene; W=hydroxy, phenoxy, C1-C8 alkoxy; phenoxy(C1-C8 alkyl), amino, (C1-C8 alkyl)amino, di(C1-C8 alkyl)amino, (when A=carbonyl, W=amino acid residue or peptide fragment); Y=-OSO2OR3(II), -OPO(OR3)2 (III), -(CH2(m-SO2OR3 (IV) or -(CH2)m-PO(OR3)2 (V) [R3=H, C1-C8 alkyl; m=1 to 4]; Z=cyclohexane, pyridyl or phenyl; n=0 to 4; on the condition that when Y=(II) or (III), -A-W is other than a sequence composed of natural amino acids. They have antipsychotic properties, an effect facilitating the memorization processes, analgesic properties; they are useful as anorexia-producing agents, and they have stimulatory effects on intestinal motility.   <IMAGE> (I)
Patent DE-68916645-D1 (DE)
Inventor: ERICKSON ROBERT
IPC: B23B29/04
Filed: 1989-08-22
Granted: 1994-08-11
Abstract: The present invention relates to an automatic clamping unit of the type having a spring loaded lock rod that is movable between an unlocked and locked position. A pair of locking balls are confined about the locking rod and are operative to move outwardly for engagement with the shank of a tool holder in response to the locking rod moving from the unlocked position to the locked position. The lock rod of the present invention includes a variable sloped ramp for engagement with each locking ball. As each locking ball moves along the variable sloped locking ramp, the mechanical advantage applied to the locking balls through the ramp varies due to the variation in slope. Each locking ramp is particularly configured such that the resultant locking load exerted by the locking balls against the shank of the tool holder is relatively constant although the position of the locking rod and the force being applied to the locking rod varies.
Patent DE-68916783-D1 (DE)
Inventor: LEITERMANN RICHARD E
IPC: A47B87/02
Filed: 1989-11-16
Granted: 1994-08-18
Abstract: A computer system module assembly has modular equipment enclosures slidable and securable in a modular exoskeletal frame structure on a base. The frame structure includes horizontal frame members (56) on which the enclosures slide with pawls (78) movable on a threaded rod to engage studs on the enclosures to clamp the enclosure to the frame. Air cooling units in the enclosures provide independent cooling for each enclosure, moving air preferably from front to back of the enclosures, through perforated frame doors.
Patent DE-69000541-D1 (DE)
Inventor: MERCAT JEAN-PIERRE
IPC: G01L5/00
Filed: 1990-01-30
Granted: 1993-01-21
Abstract: This method and this device use detecting members incorporated into the hub of the corresponding wheel and connected to an electrical circuit comprising an apparatus which indicates the value of the torque transmitted by this wheel. The detecting members that are used are electrical strain gauges (15a, 15b, 15c, 15d) arranged on one of the ends of the axle (9) of the wheel. These gauges are placed in such a way that they can be influenced only by variations in the force acting on this end in the horizontal plane passing through the centre of the wheel axle. In this way the measurement is only of the horizontal component of the shearing force on the wheel axle, from which the value of the torque transmitted to it can be deduced. Instead of being attached directly to one of the ends of the wheel axle, the strain gauges can be attached to a part connected to this end and flexible or deformable in the horizontal plane passing through the centre of the wheel axle. 
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Patent DE-69013511-D1 (DE)
Inventor: ROQUES BERNARD
IPC: C07D295/32
Filed: 1990-08-23
Granted: 1994-11-24
Abstract: Compounds having the properties of morphinic substances, particularly analgesia, with beneficial effects on behaviour and with peripheral effects without their major drawbacks (tolerence, addiction), the blood-brain barrier and having the following formula : H2N-CH(R1)-CH(R2)-S-S-CH(R3)-CH(R4)-A-B-Z wherein: AB preferably represents a CO amide bond, R2 et R3 preferably represent a hydrogen atom, R1 et R4 preferably represent, independently of each other, a benzyl grouping, -CH2CH2SCH3, -CH2-CH2-S(O)-CH3 or -CH2-CH(CH3) 2, Z may represent a -CH(R5)[CH(R6)]n-COO(R7) grouping wherein: R5 may represent a hydrogen atom, a methyl grouping, a benzyl grouping or a phenyl grouping, R6 may represent a hydrogen atom and may also form a hydrocarbon cycle with R5, or Z may represent a heterocyclic grouping, and preferably a morpholinyl grouping. No drawings.
Patent DE-69013740-D1 (DE)
Inventor: EATON MICHAEL ANTHONY WILLIAM
IPC: C07D498/04
Filed: 1990-04-05
Granted: 1994-12-08
Abstract: A drug delivery system is described in which an immunoconjugate and a prodrug are used in association with each other to deliver a drug to a host target site such as a tumour. The immunoconjugate comprises an antibody or antibody fragment to which is attached a  beta -lactamase or an active fragment thereof. The prodrug is a cyclic amide derivative of a drug or an unstable precursor thereof in which the drug or precusor is attached to the remainder of the prodrug such that it forms a leaving group which on hydrolysis of the prodrug is eliminated as the active drug or unstable precursor. Particular prodrugs include penicillin or cephalasporin derivatives and other beta -lactams to which are attached any physiologically active substances, particularly antineoplastic agents, antiviral, antibacterial or antifungal compounds. In use the immunoconjugate is adminstered first such that it localises at the host target site. Subsequent administration of the prodrug results in  beta -lactamase catalysed hydrolysis of the prodrug at the target site with release of the active drug or unstable precursor.
Patent DE-69015207-D1 (DE)
Inventor: MARTIN FRANK
IPC: A61K38/095
Filed: 1990-10-19
Granted: 1995-01-26
Abstract: A liposome composition for localizing an anti-tumor compound to a solid tumor via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids and between 1-20 mole percent of a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.12 microns. After intravenous administration, the liposomes are taken up by the tumor within 24-48 hours, for site-specific release of entrapped compound into the tumor. In one composition for use in treating a solid tumor, the compound is an anthracycline antibiotic drug which is entrapped in the liposomes at a concentration of greater than about 50  mu g agent/ mu mole liposome lipid. The method results in regression of solid colon and breast carcinomas which are refractory to anthracycline antibiotic drugs administered in free form or entrapped in conventional liposomes.
Patent DE-69016580-D1 (DE)
Inventor: LENTERS EGBERT
IPC: B23D21/04
Filed: 1990-10-19
Granted: 1995-03-16
Abstract: Described is an apparatus (26) for in-line cropping and/or chamfering of a plastic tube which comprises pressure rollers for deforming a tube section and cutting devices to perform the cropping and/or chamfering operation. The control of movement of the pressure rollers and cutting devices is carried out by a combination (12, 13) of a face cam and a rotor disc; said face cam and rotor disc have according to the invention the same diameter and may be given rotaryspeeds which are related to each other in any desired way. Control is carried out preferably with use of an interference box (6, 7). The invention also relates to a method for cropping and/or chamfering wherein the chip length can be regulated by intermittent operation of the cropping and/or chamfering action.
Patent DE-69021086-D1 (DE)
Inventor: KROFTA MILOS
IPC: B01D21/00
Filed: 1990-06-04
Granted: 1995-08-24
Abstract: Water clarifying apparatus has a cylindrical tank where particulate contaminants suspended in raw water are separated using flotation techniques. The treatment capacity of such a unit is increased by using a set of concentric, mutually spaced, conical plates positioned in the flotation tank. The apparatus utilizes air dissolving tubes operating in parallel that have common feeds and discharges coupled through three way valves operated to pressurize a closed volume of water with high pressure air in one tube while reloading and discharging the other tube.
Patent DE-69100153-D1 (DE)
Inventor: HSU JAU YANN
IPC: A23L7/109
Filed: 1991-03-01
Granted: 1993-08-12
Abstract: A process for the preparation of a rice pasta which comprises extruding or sheeting into a dough sheet a pasta mix comprising uncooked rice flour and precooked rice flour and having a maximum moisture content of 40%, followed by predrying and cutting into a pasta shape.
Patent DE-69104011-D1 (DE)
Inventor: LOUVET NATHALIE
IPC: A61K8/04
Filed: 1991-11-08
Granted: 1994-10-20
Abstract: This composition consists of a propellant and of a fatty phase containing, in combination, at least one cosmetic oil or a mixture of an oil and of a fatty substance and at least one foaming agent, characterised in that the said foaming agent corresponds to the following general formula: <IMAGE>  in which   R denotes a hydrogen atom or an alkyl radical containing from 14 to 20 carbon atoms, and   R1 denotes an alkyl radical containing from 8 to 18 carbon atoms.   This composition allows a very stable foam to be obtained.
Patent DE-69109204-D1 (DE)
Inventor: VALLE STEPHEN A
IPC: C04B40/00
Filed: 1991-08-07
Granted: 1995-06-01
Abstract: The present invention relates to a method for modifying the properties of a concrete by introducing a solid admixture, contained in a paper package, into a fresh concrete, said solid admixture being selected from the group consisting of air-entraining admixtures, air detrainer admixture, accelerating admixture, alkali-reactivity redurer, superplasticizer, pumping aids, water-reducing admixture, corrosion inhibitor, permeability reducer, fibers, and mixtures thereof; and mixing the fresh concrete in a batch type mixer for sufficient time to cause the packaging material to disintegrate and distribute the admixture relatively uniformly throughout the fresh concrete.
Patent DE-69113370-D1 (DE)
Inventor: YAMAMOTO HIDEO
IPC: C12Q1/34
Filed: 1991-07-25
Granted: 1995-11-02
Abstract: Samples of milk of humans or cattle are tested to measure the presence of 3-hydroxylacetic acid (3-OHBA), e.g. by means of a known test piece containing nicotinic acid amide adenine dinucleotide, enzymes and nitro blue tetrazolium, and the resultant color compared to a pre-prepared hue diagram. The concentration of 3-OHBA correlates with activity of N-acetyl-beta-D-glucosaminidase which has previously been a test for broken mammary tissue. The values of 3-OHBA in normal mammae and those affected by human mastitis or garget in dairy cattle can be compared, and a difference in the concentration of 3-OHBA in milk of more than 100  mu mol indicates disease of the mamma. The test is simple and allows early diagnosis.
Patent DE-69115535-D1 (DE)
Inventor: SARKAR MANISH
IPC: C08F30/08
Filed: 1991-02-19
Granted: 1996-02-01
Abstract: The invention provides a co-polymer comprising a hub portion from which radiate from 3 to 8 arms, where the hub portion being the residue of a trifunctional to octafunctional thiol and each arm is an addition polymer comprising structural units and functional units where the functional units contain hydrolysable group-bearing silicon atoms, optionally additional functional units each of which contain crosslinking groups that are the same or different and that are compatible with each other and the hydrolysable group-containing silicon atoms and optionally auxiliary functional units containing wetting groups.
Patent DE-69119292-D1 (DE)
Inventor: ANDERSON DAVID GEORGE
IPC: F16F9/36
Filed: 1991-01-02
Granted: 1996-06-13
Abstract: A buffer cartridge for absorbing energy having a hydraulic component coupled with an energy-absorbing material component, the hydraulic component having a cylinder-piston arrangement, the cylinder being surrounded by a stack of pads made from resilient energy-absorbing material, each pad being separated by a spacer. The free end of the piston emerging from the cylinder is connected to an intercoupling member which can simultaneously apply a force to both the piston and the stack of pads. A stretchable accumulator seal surrounds a piston rod within the cylinder and provides a sealing sliding path for the piston rod to isolate the moving portion of the piston rod from hydraulic fluid. The piston rod terminates in a piston having a piston hub encapsulated in resilient material and provided with orificed passageways for flow of fluid to both sides of the piston. <IMAGE>
Patent DE-69122525-D1 (DE)
Inventor: HERRAN VINCENT WAYNE
IPC: B32B27/18
Filed: 1991-02-28
Granted: 1996-11-14
Abstract: A multilayer non-irradiated film comprising a core layer, a respective further layer laminated to each side of the core layer, and an additive capable of migrating within the film, is prepared by:     (i) blending an additive, such as a fungicide, encapsulated in a first thermoplastic resin, with a second thermoplastic resin which has a lower melting point than the first resin so that during extrusion of the blend the second resin melts and surrounds the encapsulated additive before the first resin melts; and (ii) coextruding the resulting blend to provide a layer, preferably the core layer, of the film and respective thermoplastics resins to provide the other layers of the film.   Preferably a five layer film is formed in which a respective intermediate layer is provided between the core layer and each outer layer. A heat-shrinkable film may be formed by subsequently orienting the film. The film can be used to package articles such as fruit and vegetables to protect them from fungal infection.
Patent DE-69130485-D1 (DE)
Inventor: SCHAEFER KARL
IPC: B28B1/52
Filed: 1991-08-15
Granted: 1998-12-17
Abstract: A method and apparatus for producing gypsum board. The method includes the steps of mixing a predetermined amount of fibers, absorbent, and water to form a mixture of wetted, loose fibers, mixing the wetted fibers with predetermined amount of dry calcined gypsum, forming the mixture into a matt having a substantially uniform consistency and compressing the matt to form a board composed of bonded fibers and gypsum. The resulting board has a smooth exterior and can be a homogeneous or a multilayer board.
Patent DE-69209486-D1 (DE)
Inventor: MANEGLIER BRUNO
IPC: A61P43/00
Filed: 1992-12-11
Granted: 1996-05-02
Abstract: A stabilized composition comprising an effective amount of non-glycosylated recombinant human IL2 in reduced form, citric acid, mannitol and a preservative effective amount of a mixture of dextran and mono-calcium and disodium ethylenediamine tetraacetate, particularly in lyophilized form.
Patent DE-69210483-D1 (DE)
Inventor: SCHEA III
IPC: A61J1/16
Filed: 1992-01-13
Granted: 1996-06-13
Abstract: Disclosed are shipping and/or storage units for containers of liquid compositions, such as solutions of biologically active proteins, which are susceptible to physicochemical change upon freezing. Preferred container holders have double sidewalls and a freeze indicator adjacent a container-accommodating cavity. A phase change material such as a carboxymethylcellulose gel is disposed in the enclosed space between sidewalls and freezes at a temperature higher than the nucleation temperature of the composition. A freeze indicator provides an irreversible visual signal upon reaching a temperature intermediate the nucleation temperature of the liquid composition and the freezing temperature of the phase change material.
Patent DE-69214148-D1 (DE)
Inventor: TEMPLE STEPHEN
IPC: B41J2/055
Filed: 1992-06-17
Granted: 1996-10-31
Abstract: A multi-channel array droplet deposition apparatus has a base sheet comprising a layer of piezo-electric material poled normal thereto, an array of parallel, open-topped droplet liquid channels provided by upstanding channel separating walls formed in the layer, electrodes on channel facing surfaces of the walls, a channel closure sheet bonded to the walls, nozzles respectively communicating with the channels and a droplet liquid supply connecting with the channels, the closure sheet having an array of parallel conductive tracks thereon paced at intervals corresponding with the channel spacing and located parallel to and opposite the channels and bonds, which preferably are solder bonds, mechanically and electrically connect each track to the electrodes of the channel facing walls of the channels opposite thereto and seal the closure sheet to the channels.
Patent DE-69217101-D1 (DE)
Inventor: DINGLE TREVOR
IPC: B65D88/12
Filed: 1992-04-03
Granted: 1997-03-13
Abstract: A tank (10) to transport liquids. The tank (10) has an elongated shell (11) encompassing a liquid receiving chamber (12). The shell has a floor portion (21) two side wall portions (19) and a top portion (22). A plurality of walls (17, 18) spaced along the shall (10) extend transversely of the chamber (12) and are secured to the shell (11). A longitudinally extending reinforcement (24), such as a hollow aluminum extrusion, is located at the upper portions of each side wall (19) and extends laterally outward from the side wall (19).   <IMAGE>
Patent DE-69218882-D1 (DE)
Inventor: RAPPO JEAN-LOUIS
IPC: G04B37/11
Filed: 1992-10-29
Granted: 1997-05-15
Abstract: The present invention relates to a watch case comprising a back cover (6) and two clasps (8, 9) for fixing a strap, this back cover forming, together with the two clasps, a single piece (4), each clasp (8; 9) comprising a base (30), a bridge (36) connecting the said base (30) transversely to the said back cover (6) and two horns (34b; 34d) each situated at one of the two ends of the said base (30), this latter being situated substantially in a general plane (40; 41) having an angular offset ( alpha ) with respect to the general plane (38) of the said watch case, each of the said horns having an axis of general orientation (44; 45) substantially perpendicular to the said general plane (40; 41) of the said base (30) to which it is attached.   <IMAGE>
Patent DE-69218918-D1 (DE)
Inventor: VARTIJA SCOTT O
IPC: A63B47/00
Filed: 1992-01-16
Granted: 1997-05-15
Abstract: A game ball assembly for use with a game ball is described comprising a net for receiving and holding the game ball, a handle adapted to be retained within a user's hand, a length adjuster having a body part and a relatively movable locking slide part defining with said body part two paths at opposite sides of the slide part, and an elongated substantially inelastic tether cord or rope secured between the handle and the net. The tether extends through one of the paths of the length adjuster, through the net and then through the other path of the length adjuster such that a free end of the tether is supported between the slide part and the body part of the length adjuster. This arrangement facilitates simple adjustment of the length of the tether.
Patent DE-69219602-D1 (DE)
Inventor: NUGENT RICHARD
IPC: C07F9/6512
Filed: 1992-07-01
Granted: 1997-06-12
Abstract: Compounds useful in the treatment of inflammation structurally represented as <CHEM> wherein X is O or S and the R groups are as herein defined. The compounds are useful as anti-inflammatory and anti-arthritic agents without inhibiting prostaglandin synthesis.
Patent DE-69227898-D1 (DE)
Inventor: GOLDSTEIN NEIL
IPC: C12N1/21
Filed: 1992-03-13
Granted: 1999-01-28
Abstract: The present invention provides a polypeptide that is non-toxic in E. coli. The disclosed polypeptide comprises at least one antigenic sequence present in P.IA of N. gonorrhoeae and at least one antigenic sequence present in P.IB of N. gonorrhoeae. Further, the disclosed polypeptide of the invention is fused to a carrier peptide.
Patent DE-69228748-D1 (DE)
Inventor: JOHLER J RALPH
IPC: G01V3/38
Filed: 1992-05-20
Granted: 1999-04-29
Abstract: A method and apparatus in which a capacitor is disposed in direct contact with the earth, and a short voltage pulse is applied to the capacitor to transmit a pulse of electromagnetic radiation having a broad frequency band into the earth. In a preferred embodiment, a portion of the electromagnetic radiation that has propagated through the subsurface is detected and processed to image the subsurface. The size, L, of the transmitting capacitor should be sufficiently small to satisfy the relation Re[kL]<1, where k is the wavenumber in the earth formation of each frequency component of radiation transmitted into the earth. In a preferred embodiment, the voltage pulse applied to the transmitting capacitor has frequency components in a broad band from below 1 MHz to above 100 MHz, and the only frequency components of the detected electromagnetic radiation that are processed to image the subsurface have frequency in the range from about 500 KHz to 25 MHz.
Patent DE-69306415-D1 (DE)
Inventor: SONNEVILLE STEPHEN
IPC: B41F31/06
Filed: 1993-08-27
Granted: 1997-01-16
Abstract: A printing apparatus is disclosed which includes an ink reservoir, an anilox roller partially submerged in the ink reservoir, and a baffle having an array of flow restrictors submerged in the ink in the reservoir. The baffle dissipates flow energy in the ink reservoir generated by rotation of the anilox roller. In one embodiment the flow restrictors comprise parallel pegs. In a second embodiment the flow restrictors comprise parallel bristle tufts.
Patent DE-69316811-D1 (DE)
Inventor: GARTHAFFNER MARTIN T
IPC: A24C5/47
Filed: 1993-09-09
Granted: 1998-03-12
Abstract: A filter tipped cigarette making machine and method in which spaced apart generally cylindrical components are suppled to flutes in processing drums is disclosed. Gaps between the components are partially closed in a motion limiting spreader drum 5. <IMAGE>
Patent DE-69330837-D1 (DE)
Inventor: BARAN PAUL
IPC: H04N7/14
Filed: 1993-12-21
Granted: 2001-10-31
Abstract: 53 byte length ATM compliant cells are transmitted over a digital optical fiber path to interconnect with a coaxial feeder cable TV system to support two-way digital services at a plurality of sites connected to the TV cable system. At the point of interconnection between the fiber optic path and the cable TV feeder subsystem, digital signals are converted to a UHF rf carrier frequency above the cutoff pass-band of the analog signal feeder amplifier carrying TV broadcast signals. This rf carrier conveys a high data rate digitally modulated signal limited to sections of feeder cable between the cable TV broadcast channel amplifiers. In-house access to this UHF carrier signal is via the normal TV cable tap and drop cable to a SIU, located near the subscriber's TV set. The feeder cable and the passive taps used in cable TV practice have a higher cutoff frequency than the feeder amplifiers themselves. This allows passage of an UHF signal over the feeder cable. Low pass filters at the feeder amplifiers prevent this UHF signal from being shorted out by the in-cable amplifiers. Each SIU so connected sends and receives the UHF carrier signal, which conveys the ATM type cells. Each cell's payload contains the local address of the source and destination of that cell. Each SIU decodes each cell's address and accepts only those cells that are for itself. The SIUs speak to and receive signals from an FTU located at the TV cable headend or at a fiber connection node. The common channel conveying the ATM cells alternatively sends and receives cells in a ping-pong fashion.
Patent DE-69331739-D1 (DE)
Inventor: LINDBLOM RAGNVALD
IPC: A61K6/00
Filed: 1993-05-21
Granted: 2002-04-25
Abstract: Non-immunogenic enzyme compositions which have been isolated from antartic krill and exhibit both endo- and exo-peptidase activity, are useful in the manufacture of compositions for the treatment of dental plaque.