baber/WOPTO huggingface dataset:
Patent WO-2021146713-A1 (WO)
Title: Methods of treating fragile x syndrome with reelin
Inventor: WEEBER EDWIN
IPC: A61K35/761
Filed: 2021-01-19
Abstract: Fragile X syndrome (FXS) is the most common inherited form of human intellectual disability. FXS is caused by loss of function of the  FMR1  gene which results in significant behavioral deficits in spatial learning and memory tests.  FMR1 -/- knockout mice share many of the learning deficits and decreased synaptic function encountered in FXS patients. Anecdotal evidence indicates a reduction in the amount of Reelin, a large extracellular signaling protein important for normal hippocampal synaptic plasticity, may play role in the etiology of FXS. Disclosed herein is a rAAV9 Reelin viral vector expressing a REELIN repeat R3 + R6 fusion protein that is shown to rescue cognitive deficits in  FMR1-/-  mice as evaluated in the Hidden Platform Water Maze, Open Field and Fear Conditioning. Reelin gene therapy is therefore potentially a novel therapeutic for the treatment of Fragile X Syndrome.
Patent WO-2021151083-A1 (WO)
Title: Compositions of heterocyclic compounds and uses as sulfidogenesis inhibitors
Inventor: TIDWELL TIMOTHY
IPC: C09K8/532
Filed: 2021-01-25
Abstract: The present disclosure generally relates to compositions and uses of sulfidogenesis inhibitor compounds of Formulae 1 and 2 for preventing sulfidogenesis, i.e., the reduction reaction of a sulfur-containing compound by sulfur-utilizing prokaryotes that produce sulfide species such as hydrogen sulfide, during enhanced oil recovery processes. A method for inhibiting or decreasing microbial sulfide production by sulfur-utilizing prokaryotes includes addition of an effective amount of sulfidogenesis inhibitor compounds of Formulae 1 and 2 to the fluid that is injected into a sulfidogenic reservoir system during enhanced oil recovery. For example, the compounds can be used as sulfidogenesis inhibitors in a water injection system for use in a hydrocarbon extraction system or a hydrocarbon production system. Thus, these compositions can be effectively used as inhibitors of biogenic hydrogen sulfide generation in oilfield fluids.
Patent WO-2022159119-A1 (WO)
Inventor: HUANG JIUN-WOEI
IPC: G02B27/01
Filed: 2021-02-22
Abstract: L'invention concerne un dispositif qui est prévu pour générer une image réelle tridimensionnelle (3D). Un écran d'affichage est divisé en plusieurs sous-zones pour émettre des scènes. Par l'intermédiaire d'une unité de réseau de lentilles en saillie, les scènes entrent dans une unité de lentille de fusion pour former une image réelle de champ lumineux à une position au-delà de la barrière commune. Par l'intermédiaire d'une unité oculaire, l'image est émise vers l'œil humain. Ainsi, la présente invention concerne un dispositif de visualisation proche de l'œil, qui réduit le conflit d'accommodation de vergence de l'œil humain (VAC) existant dans la plupart des dispositifs de réalité augmentée et de réalité mixte. L'affichage du champ lumineux proche de l'œil est un procédé de reproduction de champ lumineux, qui fusionne les scènes et réduit l'aberration.
Patent WO-2021168434-A1 (WO)
Inventor: MASON HUGH
IPC: A61K39/00
Filed: 2021-02-22
Abstract: L'invention concerne des variants d'immunoglobuline qui sont utiles pour la conception de vaccins contre une variété d'agents pathogènes et leur procédé de production et d'utilisation. Dans certains aspects, les variants d'immunoglobuline sont des variants d'IgG, par exemple, l'anticorps 6D8.
Patent WO-2021178633-A1 (WO)
Inventor: PINSON MICHAEL
IPC: F17C7/00
Filed: 2021-03-04
Abstract: A gas supply system (1) for providing high pressure (HP) gas to a low pressure (LP) gas destination, having a primary HP gas unit and a reserve HP gas unit, which provide regulated lower-pressure gas to a supply manifold (18), and an LP destination regulator (32) that provides an LP regulated gas supply to a consumption subsystem (40). A one-way flow valve (50) in fluid communication from the primary HP gas unit to the reserve HP gas unit, ensures that the reserve HP gas unit remains substantially full, even after numerous cycles of depletion and replacement of the primary HP gas unit, during which the HP supply is provided by the reserve HP gas unit, which helps to avoid the risk that the reserve tank pressure and supply might mistakenly, unexpectedly or unintentionally be depleted.
Patent WO-2021183525-A1 (WO)
Title: Container system with a removable cap
Inventor: CREIGHTON MICHAEL
IPC: B65D50/02
Filed: 2021-03-09
Abstract: A container and methods of manufacturing and operating the same are provided where the container has a cap that is removable yet childproof. The cap is positioned in a tubular body, and the cap has a generally smooth or continuous upper surface to reduce or eliminate surfaces or edges for a child to grasp. To operate the cap, a disc in the center of the cap is pushed below a lip, and a user grasps the lip to pull the cap from the tubular body. The force needed to press the disc away from the lip is low enough for an adult but too high for a child. Moreover, the cap forms an interference fit with the tubular body with enough friction force to prevent the cap from falling out of the tubular body but is low enough that the cap can be pulled from the tubular body.
Patent WO-2021183875-A1 (WO)
Inventor: BURNS NORMAN
IPC: C12Q1/6806
Filed: 2021-03-12
Abstract: L'invention concerne des procédés et des systèmes de détection et de discrimination de signaux optiques à partir d'un substrat dense. Ces procédés et systèmes peuvent avoir de larges applications pour la détection de biomolécules à proximité ou en dessous de la limite de diffraction des systèmes optiques, notamment pour améliorer l'efficacité et la précision des applications de séquençage des polynucléotides.
Patent WO-2021184000-A1 (WO)
Title: Interleaving adc error correction methods for ethernet phy
Inventor: GANESAN RAGHU
IPC: H03M1/08
Filed: 2021-03-15
Abstract: A receiver circuit includes an interleaved ADC (106), a first delay circuit (112), a second delay circuit (114), a first processing channel, a second processing channel, and an interleaving ADC timing error detector circuit (206). The interleaved ADC(106) includes a first ADC (108) and a second ADC (110) in parallel. The first delay circuit (112) delays a first clock signal provided to the first ADC (108). The second delay circuit (114) delays a second clock signal provided to the second ADC (110). The first processing channel processes data samples provided by the first ADC (108), and includes a first sheer (138). The second processing channel processes data samples provided by the second ADC (110), and includes a second sheer (140). The interleaving ADC timing error detector circuit (206) controls delay of the first delay circuit (112) and the second delay circuit (114) based on an output signal of the first sheer (138), and an output signal or an input signal of the second sheer (140).
Patent WO-2021188547-A1 (WO)
Title: Autothermal direct air capture system
Inventor: LACKNER KLAUS
IPC: B01D53/96
Filed: 2021-03-16
Abstract: An autothermal direct air capture system (ADAC) is disclosed. The ADAC includes a chamber, a water reservoir, and a sorbent that releases water under ambient conditions, binds water under a first moisture level higher than the ambient moisture level, binds CO 2  under ambient conditions, and releases CO 2  under at least one of an elevated temperature and the first moisture level. The ADAC is movable between a capture configuration and a regeneration configuration, the capture configuration including the sorbent being exposed to a gas volume having CO 2  under ambient conditions, the sorbent binding with CO 2  while desorbing water, the sorbent selected so the sorbent material extracts heat while the ADAC is in the capture configuration, resulting in the thermal charging of the sorbent. The regeneration configuration includes the sorbent inside the chamber and in contact with water, the sorbent releasing carbon dioxide while binding water and depositing heat into the chamber.
Patent WO-2021188652-A1 (WO)
Title: Recyclable flexible films and bags for packaging flowable materials
Inventor: FARKAS NICHOLAS
IPC: B65D5/10
Filed: 2021-03-17
Abstract: The disclosure provides ethylene/ -olefin copolymer based co-extruded, multi-layer films, including barrier films and non-barrier films, and articles of manufacture that include the films, such as flexible bags and containers for flowable materials. The films and articles that include the films have improved flex-crak reisstance and toughness. The films and articles that include the films have good barrier properties as the barrier films include a core layer of ethylene-vinyl alcohol (EVOH) copolymer having a high ethylene content. The low amount of EVOH copolymer in the total film that is needed to achieve the flex-crack resistance, toughness, and good barrier properties, further allow for the recycling of the films and articles of manufacture.
Patent WO-2021211266-A1 (WO)
Title: Electronic devices having wideband antennas
Inventor: ZHANG LIJUN
IPC: H01Q7/00
Filed: 2021-03-23
Abstract: An electronic device may include a curved cover layer and an antenna. The antenna may include a ground and a resonating element on a curved surface of a substrate. The curved surface may have a curvature that matches that of the cover layer. The resonating element may include first, second, and third arms fed by a feed. The first arm and a portion of the ground may form a loop antenna resonating element. The second arm and the first arm may form an inverted-F antenna resonating element, where a portion of the first arm forms a return path to the antenna ground for the inverted-F antenna resonating element. A gap between the first and second arms may form a distributed capacitance. The third arm may form an L-shaped antenna resonating element. The antenna may have a wide bandwidth from below 2.4 GHz to greater than 9.0 GHz.
Patent WO-2021206928-A1 (WO)
Title: Integration of power and optics through cold plates for delivery to electronic and photonic integrated circuits
Inventor: GOERGEN JOEL
IPC: G02B6/43
Filed: 2021-03-25
Abstract: In one embodiment, an apparatus includes an upper cold plate and a lower cold plate, at least one of the upper cold plate or the lower cold plate comprising an electrical or optical path extending therethrough, a substrate and die package interposed between the upper cold plate or the lower cold plate, and a connector coupled to one of the upper cold plate or the lower cold plate for transmitting power or an optical signal through the electrical or optical path to the substrate and die package.
Patent WO-2021211370-A1 (WO)
Title: Method and apparatus for video coding
Inventor: LI LING
IPC: H04N19/44
Filed: 2021-04-09
Abstract: Aspects of the disclosure provide methods, apparatuses, and non-transitory computer-readable storage mediums for video encoding/decoding. An apparatus includes processing circuitry that decodes prediction information for a current block in a current picture that is a part of a coded video sequence. The prediction information includes a first syntax element indicating whether both quantization parameter (QP) information of a luma component and QP information of a chroma component of the current block are included in the prediction information. The processing circuitry determines a QP of the chroma component based on the QP information of the luma component and the QP information of the chroma component based on the first syntax element indicating that both the QP information of the luma component and the QP information of the chroma component are included in the prediction information. The processing circuitry reconstructs the current block based on the QP of the chroma component.
Patent WO-2021211779-A1 (WO)
Title: Pluggable optical module cage for fixed heat sink
Inventor: LANDS ADAM KEITH
IPC: H05K7/20
Filed: 2021-04-15
Abstract: An electronic module cage for receiving an electronic module (such as a pluggable optical module (POM)), includes a cage body mounted to a printed circuit board (PCB), the cage body having a first opening configured to receive an electronic module, the cage body comprising a spring feature, the spring feature configured to apply a biasing pressure to the electronic module in a direction away from the printed circuit board and toward a heat dissipating element such that a surface of the electronic module contacts the heat dissipating element through a second opening in the cage body.
Patent WO-2021211807-A1 (WO)
Title: Flow controller and method of use
Inventor: CARDIN DANIEL B
IPC: G01F25/00
Filed: 2021-04-15
Abstract: A flow controller for filling evacuated canisters can be operated at different reference pressures to produce substantially the same flow rates to facilitate inertness testing of the flow controller through demonstrated recovery of trace level chemicals in a challenge standard prior to using the flow controllers to collect air samples for measurement of VOCs during time weighted sampling events. The flow controller can include a first chamber and a second chamber divided by a diaphragm. The first chamber can be fluidly coupled to an inlet of the flow controller and an outlet of the flow controller. The second chamber can be coupled to a reference port of the flow controller. The outlet of the flow controller can be coupled to an initially (e.g., substantially) evacuated canister that can be used to collect a sample of ambient air or challenge standard (e.g., during testing).
Patent WO-2021222481-A1 (WO)
Inventor: RATHBURN JAMES
IPC: A62B19/00
Filed: 2021-04-28
Abstract: Embodiments described herein can include a respirator that provides pathogen exposure protection and that can be easily sterilized and reused. Embodiments described herein also include a respirator that can disable pathogens via a polymer layer defining apertures for air flow and having antiviral materials deposited on a polymer layer proximate the apertures. Embodiments described herein also include structures defining flaps therein wherein flaps have an antiviral material on at least a portion of their surface and the flaps are configured to flex at least one of inward or outward in response to force on the flaps caused by air flow during at least one of inhaling or exhaling while the mask is being worn.
Patent WO-2021231205-A1 (WO)
Inventor: SWIHART STEPHEN
IPC: G01N21/64
Filed: 2021-05-07
Abstract: L'invention concerne un système d'imagerie comprenant un appareil d'éclairage ou un appareil à épi-éclairage, doté de DEL pour l'éclairage, pour l'activation de gel sans coloration et la visualisation d'échantillons fluorescents. L'appareil d'éclairage comprend un boîtier, un réseau de sources lumineuses disposé sur au moins une surface latérale du boîtier et comprenant au moins une pluralité de DEL, chaque DEL pouvant fonctionner individuellement pour émettre une lumière d'une couleur prédéterminée dans une gamme de longueurs d'onde, et un dispositif de commande pour commander des plages de paramètres opérationnels de ladite au moins une pluralité de DEL. La lumière émise par le réseau de sources lumineuses frappe un échantillon comportant un gel qui contient un produit de réaction induite par lumière ultraviolette entre le tryptophane et un haloalcane, et la lumière émise par le réseau de sources lumineuses comprend une lumière ultraviolette (UV) pour exciter une réponse fluorescente de l'échantillon.
Patent WO-2021236487-A1 (WO)
Title: Self-organizing hanging system
Inventor: CARAWAY AUTUMN L
IPC: A47G25/06
Filed: 2021-05-17
Abstract: A self-organizing hanging system generally includes at least two main components-bars and keys. The bars have at least three embodiments: standard embodiment, valet embodiment, and shelf embodiment. Each embodiment has variations of embodiments of bars and keys. Each of the bars and keys can have embodiments of magnetic elements and anti-rotation elements. The keys have additional opportunities for variations of embodiments to couple with a product support. In at least one aspect, the bars can be formed with receiver stations at predetermined spacing to cause organized placement for coupling keys with the bars. Further, the bars and keys can be coupled to appear as an integral assembly with one or more external surfaces in planar uniformity.
Patent WO-2021232018-A1 (WO)
Title: Cross-linkable zwitterionic polymers and their use in membrane filters
Inventor: LOUNDER SAMUEL
IPC: B01D71/26
Filed: 2021-05-17
Abstract: Disclosed are copolymers, comprising a plurality of zwitterionic repeat units, and a plurality of hydrophobic repeat units, wherein the hydrophobic repeat units each independently comprises a cross-linkable moiety; the cross-linked copolymer network, comprising such copolymer; as well as thin film composite membrane comprising such cross-linked copolymer network.
Patent WO-2021236919-A1 (WO)
Title: Cells and methods for producing methyl ketones
Inventor: PFLEGER BRIAN F
IPC: C12P7/26
Filed: 2021-05-20
Abstract: Recombinant cells and methods for producing methyl ketones, such as medium-chain methyl ketones. The recombinant cells include recombinant acyl-ACP thioesterase genes, recombinant β-ketoacyl-CoA thioesterase genes, and recombinant acyl-CoA synthetase genes, in addition to other modifications. The methods include culturing the recombinant cells to produce the methyl ketones and isolating the produced methyl ketones.
Patent WO-2022010578-A1 (WO)
Title: Dual reservoir spray dispenser
Inventor: SILHAVY CHRISTOPHE
IPC: B05B11/00
Filed: 2021-05-20
Abstract: Dual reservoir spray dispenser, configured to separately hold two different components, while jointly dispensing them as a sprayable composition, comprising a common actuator comprising a pipe (2) having a sinuous path and comprising two inlet orifices (3, 5) and an outlet orifice (4).
Patent WO-2021262375-A1 (WO)
Inventor: EADS JOSH
IPC: A63F13/5375
Filed: 2021-05-25
Abstract: A method for processing a self-coaching interface is described. The method includes identifying a gameplay event during gameplay by a user. The gameplay event is tagged as falling below a skill threshold. The method further includes generating a recording for a window of time for the gameplay event and processing game telemetry for the recording of the gameplay event. The game telemetry is used to identify a progression of interactive actions before the gameplay event for the window of time. The method includes generating overlay content in the self-coaching interface. The overlay content is applied to one or more image frames of the recording when viewed via the self-coaching interface. The overlay content appeal's in the one or more image frames during a play back of the recording. The overlay content provides hints for increasing a skill of the user to be above the skill threshold.
Patent WO-2021247950-A1 (WO)
Inventor: CHEN JIE
IPC: A61C19/04
Filed: 2021-06-04
Abstract: An orthodontic force measurement system that enables duplication of the patient's dentition for the application of appliances in a simulated clinical condition. Six components of the load system on individual teeth can be measured. The device can take patient-specific information, such as shapes and locations of the teeth, and duplicate them on the device. Clinicians will be able to apply different appliances to the denture and measure the load system on specific teeth. By accurately quantifying force/moments on individual teeth, individualized, predictable patient-specific orthodontic treatments can be implemented.
Patent WO-2021257975-A1 (WO)
Title: Transpatrent mesoporous materials and devices comprising same
Inventor: LENERT ANDREJ
IPC: F24S80/65
Filed: 2021-06-18
Abstract: Thermally insulating materials (TIMs) for use in concentrated solar thermal (CST) technologies comprising a mesoporous oxide including a porous oxide matrix comprising a porous oxide and a metal oxide or metal nitride in the form of a conformal layer of the metal oxide or metal nitride on the surface of the porous oxide matrix, wherein the conformal layer completely covers the surface area of the porous oxide matrix, or in the form of metal oxide or metal nitride nanoparticles dispersed throughout the porous oxide matrix, or in the form of a conformal coating or nanoparticles, methods of preparing same, and solar devices comprising same.
Patent WO-2022015718-A1 (WO)
Title: Clad light stripper with light traps
Inventor: CARBONE KEVIN
IPC: G02B6/028
Filed: 2021-07-13
Abstract: Some embodiments may include a mounting surface defining a branching channel, the branching channel having a main channel and one or more sub-channels branching off the main channel; an optic fiber affixed to the mounting surface, the optic fiber including a cladding layer and an interior surrounded by the cladding layer, wherein part of the optic fiber is suspended over the main channel; and a clad light stripper including one or more discontinuities in an outer surface of the cladding layer of a suspended section of the optic fiber, the one or more outer surface discontinuities to release a portion of the process light; wherein the one or more sub-channels include a first sub -channel having an ingress located to capture released light from an individual one of the one or more discontinuities and trap at least a portion thereof. Other embodiments may be disclosed and/or claimed.
Patent WO-2022015927-A1 (WO)
Title: Self-limiting manufacturing techniques to prevent electrical shorts in a complementary field effect transistor (cfet)
Inventor: LIN XI-WEI
IPC: H01L21/8238
Filed: 2021-07-15
Abstract: A method of forming a complementary field effect transistor (CFET) is provided. The method includes adding a blocking material (204) to a vertical channel (207) of the CFET having an epitaxial growth (202), the blocking material being located below and in contact with a lower portion of the growth, adding an insulating material (224) to an open area within the vertical channel to surround a portion of the epitaxial growth, performing an etch to (i) remove a portion of the insulating material, (ii) expose a contact surface of the epitaxial growth and (iii) provide a vertical opening (226) within the vertical channel, the etch leaving a portion of the blocking material, and filling in the vertical opening with a conductive material, the conductive material reaching the exposed contact surface of the epitaxial growth, the blocking material remaining below the conductive material to prevent contact between the conductive material and a silicon substrate below the growth.
Patent WO-2022020709-A1 (WO)
Title: Detecting traffic signaling states with neural networks
Inventor: HSIAO EDWARD
IPC: G06K9/62
Filed: 2021-07-23
Abstract: Machine-learning models are described detecting the signaling state of a traffic signaling unit. A system can obtain an image of the traffic signaling unit, and select a model of the traffic signaling unit that identifies a position of each traffic lighting element on the unit. First and second neural network inputs are processed with a neural network to generate an estimated signaling state of the traffic signaling unit. The first neural network input can represent the image of the traffic signaling unit, and the second neural network input can represent the model of the traffic signaling unit. Using the estimated signaling state of the traffic signaling unit, the system can inform a driving decision of a vehicle.