baber/WOPTO huggingface dataset:
Patent CA-3030410-A1 (CA)
Title: Administration oculaire d'agents therapeutiques de permeation cellulaire destine au traitement de l'oedeme de la retine
Inventor: TROY CAROL M
IPC: A61K31/4458
Filed: 2017-07-11
Abstract: La présente invention concerne une méthode de traitement de l'oedème maculaire diabétique (OMD) et/ou d'une occlusion veineuse rétinienne (OVR), comprenant l'administration à la rétine du patient le nécessitant d'une quantité efficace d'un inhibiteur de la voie de signalisation de la caspase-9. L'inhibiteur de la voie de signalisation de la caspase-9 peut comprendre un inhibiteur peptidique de la caspase-9 et/ou peut être conjugué à un peptide capable de pénétrer cellulaire. La présente invention concerne en outre des compositions pharmaceutiques comprenant un inhibiteur de la voie de signalisation de la caspase-9. L'invention concerne en outre l'utilisation de telles compositions dans une méthode de traitement de l'OMD et/ou de l'OVR.
Patent CA-3031297-A1 (CA)
Title: Fabrication de poudre spherique de monocarbure de tungstene (wc)
Inventor: SHEVCHENKO RUSLAN ALEKSEEVICH
IPC: B22F9/00
Filed: 2017-07-21
Abstract: L'invention concerne la métallurgie des poudres, en particulier la production de poudres sphériques de monocarbure de tungstène, qui est un constituant principal d'alliages durs métallocéramiques utilisés pour la fabrication d'outils, de forets, d'alliage d'acier, de revêtement de revêtement résistant à l'usure au niveau d'éléments fonctionnant dans des conditions d'usure intensive. Le procédé comprend la fusion du matériau de départ, et l'atomisation à l'état fondu avec la formation de poudre sphérique. On utilise comme matériau de départ un sable de monocarbure de tungstène. La fusion et l'atomisation du matériau sont mises en uvre par remplissage continu de sable dans un creuset rotatif d'un dispositif d'atomisation centrifuge sous une atmosphère inerte et par fusion de celui-ci par un arc de plasma. Après quoi un recuit de la poudre obtenue est effectué à une température de 1200-1400 °C pendant un temps nécessaire à la rupture de W2C avec un refroidissement subséquent de la poudre dans un four. L'invention concerne la production de poudre sphérique de monocarbure de tungstène dont la teneur en WC est supérieure à 70 %.
Patent CA-3031375-A1 (CA)
Inventor: PUNDE SUSHANT ASHOK
IPC: B65H5/02
Filed: 2017-06-20
Abstract: The module (3) comprises a frame having vertical pillars (30A, 30B), a rotary turnover structure (4) arranged horizontally between the vertical pillars and comprising rotation shafts (400A) supported by bearings (300A) with which the vertical pillars are respectively equipped. A motor (303B) applies a first mechanical torque to one of the rotation shafts when a folding package turnover is ordered in the machine. The module also comprises additional means (5) for applying a second mechanical torque to the other rotation shaft upon a folding package turnover.
Patent CA-3040740-A1 (CA)
Inventor: MILLER JAY F
IPC: C07C17/383
Filed: 2017-12-14
Abstract: Aspects of the invention relate to systems and processes for recovering R1233zd in purified form from compositions additionally comprising hydrogen fluoride. In accordance with one aspect, the invention provides a process that includes separating a feed stream comprised of hydrogen fluoride and R1233zd using azeotropic distillation in a first distillation column to produce a first distillate stream comprised of hydrogen fluoride and R1233zd and a first bottoms stream consisting essentially of hydrogen fluoride. The first distillation column is operated at a first pressure. The process further includes separating the first distillate stream using azeotropic distillation in a second distillation column to produce a second distillate stream comprised of hydrogen fluoride and R1233zd and a second bottoms stream consisting essentially of R1233zd. The second distillation column is operated at a second pressure that may be different than the first pressure of the first distillation column.
Patent CA-3042258-A1 (CA)
Title: Dispositif d'acces vasculaire simple et double a profil bas
Inventor: FEDOR BRENDA L F
IPC: A61M39/02
Filed: 2017-11-10
Abstract: L'invention concerne un orifice d'accès à profil bas pour une implantation sous-cutanée à l'intérieur d'un patient. L'orifice d'accès comprend une coupelle de réception qui fournit une cible sous-cutanée relativement grande pour permettre un accès d'aiguille de support de cathéter à l'orifice sans difficulté. Selon un mode de réalisation, un orifice d'accès à profil bas comprend un corps comprenant un conduit ayant un orifice d'entrée au niveau d'une extrémité proximale, et une coupelle de réception. La coupelle de réception est en forme d'entonnoir pour diriger une aiguille de support de cathéter dans le conduit par l'intermédiaire de l'orifice d'entrée. Le conduit est défini par le corps et s'étend depuis l'orifice d'entrée jusqu'à une sortie définie par une tige. Un coude dans le conduit permet l'avancement du cathéter au-delà du coude tout en empêchant la progression de l'aiguille. Un ensemble valve/joint est également disposé dans le conduit et permet le passage du cathéter à travers celui-ci tout en empêchant un reflux de fluide. Le corps comprend des indices radio-opaques configurés pour permettre l'identification de l'orifice d'accès par l'intermédiaire d'une imagerie par rayons x.
Patent CA-3043538-A1 (CA)
Title: Welding-type system with controller for calculating output inductance of a weld secondary associated non-transitory machine readable storage device
Inventor: HUTCHISON RICHARD M
IPC: B23K9/095
Filed: 2017-11-15
Abstract: A welding-type system (100) includes a welding-type power supply (102) to output welding-type power, and a controller (110) connected to the welding-type power supply (102). The controller (110) is configured to set a value of a control variable of a control loop of the welding-type power supply (102), the control loop controlling the welding-type power (102). The controller (110) is also configured to adjust the value of the control variable while monitoring the control loop. In response to detecting oscillation in the control loop, the controller (110) is configured to determine a weld circuit inductance associated with a weld circuit of the welding-type system (100) based on a relationship between the adjusted control variable value and the weld circuit inductance.
Patent CA-3044658-A1 (CA)
Inventor: OZAWA YOICHI
IPC: A61K31/53
Filed: 2018-02-06
Abstract: Provided is a tumor-treating pharmaceutical composition used in combination therapy of lenvatinib and (6S,9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazin-1(6H)-carboxamide.
Patent CA-3044686-A1 (CA)
Inventor: HEYNES CHRISTOPHER MICHAEL
IPC: A61K39/395
Filed: 2017-12-21
Abstract: La présente invention concerne des méthodes et des formulations utiles pour réduire le temps de reconstitution de polypeptides lyophilisés.
Patent CA-3044811-A1 (CA)
Title: Methods and systems for controlling the heading of a mining machine
Inventor: DAVIS LEE
IPC: E21C35/08
Filed: 2019-05-31
Abstract: Methods and systems for controlling the heading of a mining machine while the mining machine performs a cutting operation. One system includes a cutting system and a set of left and right tracks of the mining machine. The system also includes a lidar sensor mounted to the mining machine. The system also includes an electronic processor configured to receive the data from the lidar sensor. The electronic processor is also configured to determine a current heading of the mining machine based on the data received from the lidar sensor and compare the current heading to a target heading of the mining machine. In response to the current heading not being different from the target heading of the mining machine by a predetermined amount, the electronic processor is configured to control the mining machine to adjust the current heading of the mining machine.
Patent CA-3045237-A1 (CA)
Inventor: BARBASH OLENA
IPC: A61K31/506
Filed: 2017-11-30
Abstract: La présente invention concerne l'association d'un inhibiteur de la protéine arginine N-méthyltransférase de type 1 (PRMT1) et d'un inhibiteur de la protéine arginine N-méthyltransférase de type 2 (PRMT2). La présente invention concerne également des méthodes de traitement du cancer chez le patient humain en ayant besoin, les méthodes comprenant l'administration au patient d'une association d'un inhibiteur de la PRMT1 et d'un inhibiteur de la PRMT2, avec au moins l'un des constituants suivants : un support pharmaceutiquement acceptable et un diluant pharmaceutiquement acceptable, l'invention permettant de cette façon de traiter le cancer chez l'humain. La présente invention concerne en outre une composition pharmaceutique comprenant une quantité thérapeutiquement efficace d'un inhibiteur de la PRMT1, et une seconde composition pharmaceutique comprenant une quantité thérapeutiquement efficace d'un inhibiteur de la PRMT2.
Patent CA-3046411-A1 (CA)
Title: Compositions comprising a fiber material and a thermoplastic binder
Inventor: NIEGEMEIER ANDREAS
IPC: C08G18/42
Filed: 2017-12-04
Abstract: The invention relates to compositions comprising a fiber material and a specific thermoplastic binder. The thermoplastic binder comprises at least one thermoplastic polyurethane polymer, wherein said thermoplastic polyurethane polymer comprises a reaction product of (i) at least one semi-crystalline polyester polyol, and (ii) at least one polyisocyanate. The molar ratio of the NCO groups of said polyisocyanate (ii) to the sum of OH groups of said polyester polyol (i) is less than 1.00:1 and the thermoplastic polyurethane polymer has (a) a melting enthalpy of at least 20 J/g, (b) a melting point (Tm) of >70 °C, and (c) an average number molecular weight (Mn) of 5,000 to 80,000 g/mol. Furthermore, the present invention relates to a fiber-reinforced composite comprising a cured thermosetting polyurethane polymer matrix reinforced by the composition according to the present invention. Moreover, a method for the manufacture of the fiber-reinforced composite according to the present invention and use of the composition or the fiber-reinforced composite in railway vehicles, automotive vehicles, aircraft vehicles, boats, space vehicles, motorbikes, bicycles, sporting goods, helmets, functional clothing, shoes, construction parts in bridges and buildings or wind turbine blades are described.
Patent CA-3047564-A1 (CA)
Title: Methode et systeme de determination d`une charge tumorale dans des images medicales
Inventor: GUPTA MAYANK
IPC: G06T7/10
Filed: 2019-06-21
Abstract: Il est décrit une méthode et un système servant à déterminer la charge tumorale dans un système. Selon un aspect, la méthode comprend lobtention dune image médicale auprès dune source par lintermédiaire dune interface. De plus, la méthode comprend la détermination dune première zone dintérêt dans limage médicale. La méthode comprend également la sélection dune deuxième zone dintérêt à lintérieur de la première zone dintérêt dans laquelle il faut déterminer la charge tumorale. La méthode comprend la définition de critères de segmentation pour la deuxième zone dintérêt. Finalement la méthode comprend la détermination de la charge tumorale dans la deuxième zone dintérêt.
Patent CA-3048008-A1 (CA)
Inventor: KISTNER MATTHEW WAYNE
IPC: B65D5/42
Filed: 2017-12-20
Abstract: A folded blank (10) for forming a display case (8) and a display case (8) formed from the folded blank (10). The folded blank (10) comprises a one-piece blank (10) including a first panel (24), a second panel (26), a third panel (28) and a fourth panel (30) connected in series at respective first, second and third vertical fold lines (32, 34, 36). The first panel is folded about the first vertical fold line and is engaged on a first portion of the second panel at a first manufacturer's joint strip (64). The fourth panel (30) is folded about the third fold line (36) and is engaged on the first panel (24) at a second manufacturer's joint strip (66). The first portion forms a tear-away section (26a) defined by at least one separation line on the second panel (26). The first manufacturer's joint strip (64) retains the tear-away section (26a) in engagement with the first panel (24) during erection of the folded blank (10) to form the display case (8) having a display window. The invention comprises also a method of forming a display case (8) from the blank (10).
Patent CA-3049266-A1 (CA)
Title: Drainable ostomy pouch
Inventor: WEINBERG ROBERT J
IPC: A61F5/445
Filed: 2018-01-19
Abstract: A drainable ostomy pouch outlet includes a single-piece closure member including at least one transversely-extending fold-line. The at least one transversely-extending fold-lines are configured to facilitate folding up and closing of the outlet. The single-piece closure member may also include at least one axially-extending or slanted fold-lines intersecting the at least one transversely-extending fold-line, configured to facilitate opening of the outlet.
Patent CA-3055820-A1 (CA)
Inventor: STEGER BEAT
IPC: A61K9/00
Filed: 2018-03-06
Abstract: The invention relates to a contrast medium for ex vivo microangiography for digital imaging of the vascular system of a mouse or rat or other laboratory animals, and of individual animal and human organs, comprising an iodized, esterified oil, a polyurethane, and a hardener. The invention further relates to a method for producing the contrast medium; to a kit of parts, comprising the various containers having the components of the contrast medium according to the invention that are to be mixed; and to a preferred use of the contrast medium according to the invention for imaging by means of a micro-CT device.
Patent CA-3056760-A1 (CA)
Title: Systeme et procede de traitement des eaux usees
Inventor: LABRECQUE MARISOL
IPC: C02F3/30
Filed: 2017-03-14
Abstract: L'invention concerne un système pour le traitement des eaux usées dans un bassin ou une lagune contenant un certain volume d'eau. Le système comprend au moins une enceinte comportant un milieu de croissance et/ou un substrat pour la croissance de bactéries et/ou de biomasse. Ladite enceinte est conçue dans le bassin ou la lagune pour recevoir un certain volume d'eaux usées provenant du bassin ou de la lagune sur une période de traitement donnée, et est conçue pour traiter sensiblement tout le volume d'eau traversant le bassin ou la lagune au cours du temps. Une pluralité de milieux de croissance et/ou de substrats peuvent alimenter une enceinte donnée. Différentes enceintes peuvent comprendre différents milieux de croissance et substrats.
Patent CA-3057272-A1 (CA)
Inventor: RADTKE CAMERON
IPC: E21B17/04
Filed: 2019-09-30
Abstract: A downhole coupling mechanism for use in downhole tools that find application in wells exploited by a hydraulic refracturing process. The downhole coupling mechanism connects first and second tubular sections via a tensile load arrangement of wires located in complimentary grooves, a torque arrangement of interlocking lugs and notches on opposite ends, and a seal arrangement. The downhole coupling mechanism provides a thin walled coupling where a screw-threaded connection could not achieve the required tensile load, torque and sealing properties needed. Embodiments of a thin walled anchor and packer including the downhole coupling mechanism are described.
Patent CA-3058201-A1 (CA)
Title: Pin seamed press felt and method of making same
Inventor: POSTL FRIEDRICH
IPC: D21F1/00
Filed: 2018-05-30
Abstract: A method of making a fabric for a press felt for a papermaking machine includes: -    forming a base fabric comprising repeat units, comprising cross machine direction (CMD) yarns and two sets of machine direction (MD) yarns interwoven with the CMD yarns, the first set of yarns including seam loops at their ends that capture a first pintle and the second set including loops at their ends that capture a second pintle that is positioned above the first pintle; -    removing the second pintle from the ends of the second set of yams; and -    tensioning the fabric so that each of the ends of the second set of yarns forms a gap of no more than about 0.3 min with a respective end of first set of MD  yarns that approaches the seam from the opposite direction.
Patent CA-3058632-A1 (CA)
Title: Self-adapting gas turbine firebox with variable geometry
Inventor: GUIN CHRISTIAN
IPC: F23N5/04
Filed: 2018-04-11
Abstract: The invention relates to a self-adapting gas turbine firebox with variable geometry, comprising at least one system with a variable opening for automatically adjusting a configuration of the combustion inside a combustion chamber (101) according to an air temperature, particularly air from a compressor. The adjustment is performed by a thermosensitive element that controls at least one section towards the combustion chamber, for the air that participates in the combustion of the fuel, or participates in a dilution of the gases effective inside the combustion chamber.
Patent CA-3058895-A1 (CA)
Title: Improved conveyor belt assembly for identifying an asset sort location and methods of utilizing the same
Inventor: GIL JULIO
IPC: B07C7/00
Filed: 2018-01-17
Abstract: Provided are systems and methods for associating an asset with a sort location, the system comprising a conveyor belt assembly and a user device configured to be worn by a user. The conveyor belt assembly comprises: an acquisition device and a plurality of stripes defining a non-repeating pattern, the plurality of stripes comprising a plurality of unique sets of stripes. The acquisition device is configured to capture image data comprising asset identifier data and conveyor mechanism data, the conveyor mechanism data including one of the plurality of unique sets of stripes. The user device is configured to capture conveyor mechanism data including one of the plurality of unique sets of stripes; remotely receive asset identifier data associated with the user device captured conveyor mechanism data; and generate and display to the user, relative to the asset, at least one visual indicator of one or more sort instructions for the asset.
Patent CA-3060083-A1 (CA)
Title: Contamination resistant poppet valves
Inventor: WOJICK TROY GILCHRIST
IPC: F16K11/07
Filed: 2018-04-17
Abstract: A multi-way poppet valve and methods for using the same are provided. In one embodiment, the poppet valve includes a manifold and a poppet assembly including an inner poppet and an outer poppet defining one or more lands. The poppet assembly can dimensioned for receipt within a bore of the manifold and configured to move longitudinally within the manifold. The inner poppet and the outer poppet can also be formed in two separate pieces that are capable of moving with respect to one another. This design can allow the lands of the poppet assembly to form fluid-tight seals (e.g., metal-metal, metal-gasket, etc.) with the manifold. In this manner, the poppet valve can move longitudinally between open and closed positions where the fluid-tight seals respectively allow or inhibit fluid flow between selected ports of the valve.
Patent CA-3061473-A1 (CA)
Inventor: CHRIMES ADAM
IPC: G01N33/00
Filed: 2018-05-04
Abstract: Disclosed herein is a method for determining a type and corresponding concentration of at least one gas in a multi-gas mixture, the method including: exposing a gas sensitive element of a gas sensor to the multi-gas mixture; modulating a drive signal supplied to a temperature control element of the gas sensor to cause a temperature of the gas sensitive element to change from an initial temperature; recording a transient impedance response of the gas sensitive element while the temperature of the gas sensitive element changes to obtain a transient impedance response that is characteristic of the multi-gas mixture; using the transient impedance response to determine a type and corresponding concentration of at least one gas in the multi-gas sample from a database including calibration data corresponding to the at least one gas. Also disclosed herein is a method of calibrating a multi-gas sensing system, a multi-gas sensing system, and related methods for determining a type and corresponding concentration of at least one gas in a multi-gas mixture.
Patent CA-3061585-A1 (CA)
Title: Silicone hydrogel contact lenses
Inventor: WU DAQING
IPC: G02B1/04
Filed: 2018-06-06
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses formed from a silicone hydrogel lens formulation that comprises a polysiloxane vinylic crosslinker having H-donor moieties, a siloxane-containing vinylic monomer with or without H-donor moieties, and a N-vinyl amide monomer. The inherently wettable silicone hydrogel contact lenses can have a combination of the desired contact lens properties including relatively high oxygen permeability, relatively high water content, relatively low modulus, and relatively-low surface atomic Si percentage. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
Patent CA-3064800-A1 (CA)
Inventor: XIE ZIJIAN
IPC: G01N33/53
Filed: 2018-05-25
Abstract: Expression vectors are provided that comprise a nucleic acid sequence encoding a polypeptide antagonist of a Na/K ATPase/Src receptor complex. The nucleic acid encoding the polypeptide antagonist is operatively linked to a promoter for expressing the polypeptide antagonist in a specific cell or tissue. Viral particles, target cells, and pharmaceutical compositions are also provided and include the expression vectors. Methods of treating a Src-associated disease is further provided and includes adminstering the expression vectors encoding the polypeptide antagonist of the Na/K ATPase/Src receptor complex to a subject in need thereof.
Patent CA-3067151-A1 (CA)
Inventor: ROOT ROBERT EDWIN
IPC: G07C5/08
Filed: 2020-01-07
Abstract: A device for tail-specific parameter computation includes a memory, a network interface, and a processor. The memory is configured to store a tail-specific aircraft performance model for a first aircraft of an aircraft type. The tail-specific aircraft performance model is based on historical flight data of the first aircraft and a nominal aircraft performance model associated with a second aircraft of the aircraft type. The network interface is configured to receive flight data from a databus of the first aircraft. The processor is configured to generate, based at least in part on the flight data and the tail-specific aircraft performance model, a recommended cost index and a recommended cruise altitude. The processor is also configured to provide the recommended cost index and the recommended cruise altitude to a display device.
Patent CA-3067372-A1 (CA)
Inventor: RINGOLD RANDY
IPC: G01N1/28
Filed: 2018-06-13
Abstract: Des échantillons de sang sont maintenus dans un environnement scellé à atmosphère modifiée, où l'humidité est réduite à l'aide d'un déshydratant et l'oxygène est éliminé à l'aide d'un composé de désoxygénation, ce qui permet la conservation de nombreux analytes sanguins, pour un test sanguin retardé (par exemple 14 jours après la collecte), par exemple de l'activité enzymatique, de la concentration de protéine et de la mesure d'autres composants sanguins dans des applications de tests sanguins humains et vétérinaires.