baber/WOPTO huggingface dataset:
Patent EP-3483289-A1 (EP)
Inventor: PETROPOULOS CHRISTOS
IPC: C12Q1/70
Filed: 2005-06-07
Abstract: The invention provides a method for determining whether a human immunodeficiency virus is resistance to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor.
Patent EP-3461525-A1 (EP)
Inventor: BEHAN NIALL
IPC: A61F2/00
Filed: 2011-11-03
Abstract: A urological device 800, 810, 830, 850, 860, 870, 900, 910, 920 comprises a urological valve 802, 803, 812, 861, 901, for location in the bladder of a patient and a valve support stem 801, 813, 863, 902, for location in the urethra of a patient. The valve has a normally closed configuration to prevent flow from the bladder and an open configuration for fluid flow through the valve. The valve is automatically movable from the closed configuration to the open configuration in response to a pre-set hydrodynamic pressure applied for a pre-set time. In one case the valve has a plurality of valve leaflets with a region of co-aption between the valve leaflets. In the normally closed configuration the valve leaflets are engaged at the region of co-aption and in the open configuration the leaflets are separated at the co-aption region for fluid flow through the valve.
Patent EP-3473080-A1 (EP)
Inventor: PASA JOSHUA J
IPC: A01F15/04
Filed: 2018-10-17
Abstract: A baler (10) is provided that includes a housing (22) that defines a baling chamber (24) and a plunger (46) movable along an axis (A) within the baling chamber (24) to compress the crop material. The baler includes a first guide rail (110) coupled to an exterior surface (27.1, 29.1) of the baling chamber (24) and a second guide rail (112) coupled to the exterior surface (27.1, 29.1) of the baling chamber (24). The baler includes at least one bearing (114) coupled to the plunger (46) to guide a movement of the plunger (46) within the baling chamber (24). The bearing (114) has a first bearing surface, a second bearing surface (S2) and a third bearing surface (S3). The first bearing surface engages the first guide rail (110), the second bearing surface (S2) engages the first guide rail (110) and the third bearing surface (S3) engages the second guide rail (112) to constrain a vertical movement and a lateral movement of the plunger (46) relative to the baling chamber (24).
Patent EP-3456715-A1 (EP)
Inventor: ZHANG XIAOMING
IPC: C07C69/708
Filed: 2016-06-14
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Patent EP-3553894-A1 (EP)
Inventor: MAYER FLORIAN
IPC: H01R13/641
Filed: 2018-11-20
Abstract: Das Problem, mit dem sich die vorliegende Erfindung befasst, liegt in dem leichten Aufrechterhalten eines Zustands, in dem mehrere Verbinder sicher zusammengefügt sind.Eine Verbindungsstruktur (S) ist eine Struktur zur Verbindung eines ersten Verbinders (1) und eines zweiten Verbinders (2). Der erste Verbinder (1) umfasst ein erstes Gehäuse (11), das um den ersten Verbindungsanschluss (10) herum vorgesehen ist und mindestens eine Öffnung (12) aufweist, und der zweite Verbinder (2) umfasst ein Gehäuse (21), das um den zweiten Verbindungsanschluss (20) herum vorgesehen ist und einen Eingriffsabschnitt (22) aufweist, der in einem Zustand, in dem der erste Verbindungsanschluss (10) und der zweite Verbindungsanschluss (20) zusammengefügt sind und das zweite Gehäuse (21) mit dem ersten Gehäuse (11) zusammengefügt ist, in die in dem ersten Gehäuse (11) ausgebildeten Öffnung (12) eingreift, und ein Verriegelungsglied (24), das sich in eine Längsrichtung der Verbindungsstruktur (S) bewegen kann und eine Verschiebung des Eingriffsabschnitts (22) in eine Richtung des Ausrückens aus der Öffnung (12) in einem Zustand, in dem das Verriegelungsglied (24) bis zu einer vorbestimmten Position auf der Seite des ersten Verbinders (1) eingeschoben ist, verhindert.
Patent EP-3663786-A1 (EP)
Title: Normalized mr relaxation parameter
Inventor: RODELL ANDERS BERTIL
IPC: G01R33/48
Filed: 2018-12-05
Abstract: The invention relates to a method for determining a normalized MR relaxation parameter for an object under examination using an imaging sequence in which the MR signal of the object under examination is detected at a first echo time TE1 and at a second echo time TE2, the method comprising, determining the first MR signal for the object under examination obtained at the fist echo time TE1, determining the second MR signal for the object under examination obtained at the second echo time TE2, determining a first reference MR signal obtained at the first echo time TE1 from a reference tissue having a known value for the MR relaxation parameter, determining a second reference MR signal obtained at the second echo time TE2 from the reference tissue, calculating the normalized MR relaxation parameter based on the first MR signal, the second MR signal, the first echo time TE1, the second echo time TE2, and the first and second reference MR signal.
Patent EP-3552658-A1 (EP)
Inventor: KELP MARTIN
IPC: A61M37/00
Filed: 2018-12-10
Abstract: Die Erfindung betrifft ein Antriebsmodul (2) für ein Handgerät zum wiederholten lokalen Aufstechen einer menschlichen oder einer tierischen Haut mit einem Antriebsmodul-Gehäuse (1a); einer maschinellen Antriebseinrichtung (4), die in dem Antriebsmodul-Gehäuse (1a) angeordnet und eingerichtet ist, eine Antriebskraft bereitzustellen; und einem antriebsseitigen Kopplungselement, welches in dem Antriebsmodul-Gehäuse (1a) angeordnet ist, an die Antriebseinrichtung (4) koppelt und eingerichtet ist, die bereitgestellte Antriebskraft auf ein abtriebsseitiges Kopplungselement, welches außerhalb des Antriebsmodul-Gehäuses (1a) an einem Nadelmodul (3) und dort an eine Stecheinrichtung (7) koppelnd angeordnet ist, kontaktlos zu übertragen. Ferner werden ein Nadelmodul (3) für ein Handgerät zum wiederholten lokalen Aufstechen einer menschlichen oder einer tierischen Haut sowie ein Handgerät zum wiederholten lokalen Aufstechen einer menschlichen oder einer tierischen Haut bereitgestellt.
Patent EP-3496183-A1 (EP)
Inventor: BADDING MICHAEL EDWARD
IPC: H01M50/497
Filed: 2013-08-21
Abstract: An ion-conducting composite electrolyte (10) is provided comprising path-engineered ion-conducting ceramic electrolyte particles (20) and a solid polymeric matrix (30). The path-engineered particles (20) are characterized by an anisotropic crystalline structure and the ionic conductivity of the crystalline structure in a preferred conductivity direction H associated with one of the crystal planes of the path-engineered particle is larger than the ionic conductivity of the crystalline structure in a reduced conductivity direction L associated with another of the crystal planes of the path-engineered particle. The path-engineered particles are sized and positioned in the polymeric matrix (30) such that a majority of the path-engineered particles breach both of the opposite major faces (32, 34) of the matrix body and are oriented in the polymeric matrix (30) such that the preferred conductivity direction H is more closely aligned with a minimum path length spanning a thickness of the matrix body than is the reduced conductivity direction L.
Patent EP-3503327-A1 (EP)
Inventor: TROUGHTON ANDRE
IPC: H02G3/32
Filed: 2018-12-18
Abstract: A wire harness retention system includes a harness bracket having a cable tie retention feature and a spring clip attached to the harness bracket. A cable tie is wrapped around the spring clip. The cable tie is held in place with the cable tie retention feature on the harness bracket.
Patent EP-3605326-A1 (EP)
Inventor: PICARD JEAN-CHARLES
IPC: G06F9/451
Filed: 2018-07-31
Abstract: Example implementations relate to combining computer applications by adding a new computer application to a common access point. The new computer application accesses a new data source via the common access point. The new computer application is associated with an existing computer application. The existing computer application accesses an existing data source via the common access point. The existing computer application is executed to access the existing data source. Additionally, the new computer application is executed to access the new data source in response to a selection of the association.
Patent EP-3477344-A1 (EP)
Inventor: NICOLAS FRÉDÉRIC
IPC: H01R13/523
Filed: 2018-10-02
Abstract: Method and streamer connecting module for connecting streamer sections to each other. The streamer connecting module (317) includes a housing (319) extending along a longitudinal axis (L) so that first and second ends (319A, 319B) are opposite to each other; a first streamer connecting part (330) fixedly attached at the first end (319A) of the housing (319); a second streamer connecting part (340) fixedly attached at the second end (319B) of the housing (319); first plural balls (333A) located between the first streamer connecting part (330) and the first end (319A) of the housing (319); and a first conduit formed at an interface between the first streamer connecting part and the first end of the housing for accommodating the first plural balls.
Patent EP-3664289-A1 (EP)
Title: Power amplifier with integrated bias circuit having multi-point input
Inventor: HUE XAVIER
IPC: H03F3/195
Filed: 2018-12-05
Abstract: A power amplifier includes a semiconductor die, and an amplifier and bias circuit integrally formed with the semiconductor die. The die has opposed first and second sides, and a device bisection line extends between the first and second sides. The bias circuit includes a multi-point input terminal with first and second terminals that are electrically connected through a conductive path that extends across the device bisection line, and one or more bias circuit components connected between the multi-point input terminal and the amplifier. The amplifier may include a field effect transistor (FET) with gate and drain terminals, and the bias circuit component(s) are electrically connected between the multi-point input terminal and the gate terminal. In addition or alternatively, the bias circuit component(s) are electrically connected between a multi-point input terminal and the drain terminal. The one or more components may include a resistor-divider circuit.
Patent EP-3655411-A1 (EP)
Title: Method for preparing silicon-containing heterocycles
Inventor: DAMKE JAN-ERIK
IPC: C07F7/18
Filed: 2018-02-15
Abstract: The present invention relates to a method for preparing silicon-containing heterocycles of the general formula (I), wherein R 1  is hydrogen; R 2  and R 3  are same or different and are, independently from one another, selected from a linear or branched, substituted or unsubstituted C 1 -C 20  alkyl or C 6 -C 18  aryl residue which may be interrupted by at least one heteroatom; R 4  is selected from a linear or branched C 1 -C 20  alkylene residue which may be interrupted by at least one heteroatom; R 5  and R 6  are same or different and are, independently from one another, selected from the group consisting of hydrogen, a linear or branched, substituted or unsubstituted C 1 -C 20  alkyl or C 6 - C 18  aryl which may be interrupted by at least one heteroatom, and a C 4 -C 8  cycloalkyl, or R 5  and R 6  may form a ring, preferably a 4- to 8-membered alkyl ring; and n is 0, 1 or 2, preferably 2, said method comprising a one-step reaction of at least one epoxide compound of the general formula (II) and at least one aminoalkoxysilane having a primary amino group in the presence of a catalyst formula (II), wherein R 5  and R 6  are the same as defined for the general formula (I) above; as well as the use of the silicon-containing heterocycles of the general formula (I).
Patent EP-3585368-A1 (EP)
Inventor: WRIGHT STEPHEN
IPC: A61K31/05
Filed: 2018-02-16
Abstract: La présente invention concerne l'utilisation d'une combinaison de deux cannabinoïdes différents dans le traitement de la leucémie. La combinaison de CBD et de THC s'est révélée particulièrement efficace pour réduire le nombre de cellules dans cette maladie. De préférence, les cannabinoïdes sont utilisés sous la forme d'un extrait de cannabis de telle sorte qu'un grand nombre des composés naturels sont extraits simultanément avec le THC ou le CBD. Alternativement, les cannabinoïdes sont présents sous la forme d'un extrait extrêmement purifié de cannabis, la teneur en CBD ou en THC étant de plus de 98 % (en poids) de l'extrait total et les autres constituants de l'extrait étant caractérisés. Alternativement, le CBD et le THC peuvent être produits de manière synthétique. Un rapport spécifique de CBD et de THC, qui serait compris entre 10 / 1 et 1 / 10 (CBD / THC) ou mieux encore entre 2 / 1 et 1 / 2 (CBD / THC) peut être utilisé.
Patent EP-3589650-A1 (EP)
Inventor: CEBE REGIS
IPC: C07K16/28
Filed: 2018-03-01
Abstract: The present invention provides heterodimeric antibodies and fragments thereof and methods for their preparation, wherein the pairing of heavy and light chains has been improved. Interface residues were mutated such that each light chain strongly favoured its cognate heavy chain when two different heavy chains and two different light chains were co-transfected and co-expressed in the same cell to assemble a functional, heterodimeric antibody or fragment thereof.
Patent EP-3606696-A1 (EP)
Inventor: SPÖRL GEORG
IPC: B23K26/046
Filed: 2018-03-22
Abstract: The invention relates to method and device for controlling a focus point of a working laser beam (14) for machining workpieces (20) and a laser machining head (10) equipped therewith in which the focus point of the working laser beam (14) is adjusted by displacing an optical system (24) along an optical axis (26) of the optical system (24) by means of an actuator motor (28). The method comprises the following steps: - generating and outputting a specification for a current control circuit (40) of the actuator motor (28) with a position controller (38) in order to move the optical system (24) into a target position and hold it there, - detecting an acceleration acting in the direction of the optical axis of the optical system with an acceleration sensor (48), and - varying the specification that is output for the current control circuit (40) of the actuator motor (28) on the basis of the detected acceleration using a pilot circuit (50), such that the actuator motor (28) generates an additional force which counteracts the force generated by the detected acceleration.
Patent EP-3602645-A1 (EP)
Title: Ultra-thin plasmonic solar cells, methods for their manufacture and use
Inventor: DE PAIVA SÁ JACINTO
IPC: H01L51/05
Filed: 2018-03-28
Abstract: An ultra-thin and highly transparent wafer-type plasmonic solar cell comprising a layer of a conductive transparent substrate, a layer of an n-type semiconductor; a layer made of metal nanoparticles selected from the group consisting of copper, gold or silver; and a layer made of a p-type semiconductor; wherein the substrate, n-type semiconductor, metal nanoparticles and p-type semiconductor respectively are linked by covalent bonds by means of one or more molecular linker / linkers. A method for producing said plasmonic solar cell by self- assembly.
Patent EP-3612573-A1 (EP)
Inventor: THUILLIEZ JULIEN
IPC: C08F210/02
Filed: 2018-04-16
Abstract: The present invention relates to a method for the synthesis of an ethylene and butadiene copolymer, characterised in that the method is continuous and comprises the following concurrent steps: a) feeding at least one stirred polymerisation reactor with a mixture of ethylene, butadiene, a hydrocarbon solvent and a catalytic system, whereby cyclic trans-1,2-cyclohexane units are formed in the polymer chain with a mole ratio of ethylene to the sum of the ethylene and butadiene monomers, defined by QnE/(QnE + QnB), with QnE being the molar flow rate of ethylene, and QnB the molar flow rate of butadiene, ranging from 0.5 to 0.99; the concentration of ethylene and butadiene monomers in the polymerisation reaction medium being at least 10 wt.% relative to the total weight; and the operating pressure of the reactor being at least equal to the saturation vapour pressure of the polymerisation reaction medium; b) recovering the ethylene and butadiene copolymer, which copolymer comprises, in statistical distribution, ethylene units, butadiene units and trans-1,2-cyclohexane units, the mole fraction of ethylene units in said copolymer being at least 50% of the total number of moles of ethylene, butadiene and trans-1,2-cyclohexane units.
Patent EP-3619835-A1 (EP)
Inventor: GOHEL TUSHAR K
IPC: H04B10/073
Filed: 2018-04-02
Abstract: An example system includes non-transitory machine-readable storage storing calibration data sets. A calibration data set includes parameter values that vary non-linearly. Each of the calibration data sets is temperature-specific. The example system also includes channels over which signals pass to and from units under test (UUTs). A channel includes input circuitry to receive a signal of the signals and to obtain a first parameter based on the signal; and correction circuitry to obtain a second parameter based on the first parameter and based on the calibration data set. The second parameter includes a calibrated version of the first parameter. The calibration data set is selectable based on temperature.
Patent EP-3625893-A1 (EP)
Inventor: FAKOORIAN SEYED ALI AKBAR
IPC: H04B7/0456
Filed: 2018-04-18
Abstract: Methods, systems, and devices for wireless communication are described. A user equipment (UE) may obtain an interference and noise covariance matrix for a plurality of antennas of the UE. The UE may generate an approximated covariance matrix based on the inference and noise covariance matrix and a number of the antennas of the plurality of antennas associated with transmit operations at the UE. The number of the antennas associated with transmit operations at the UE may be fewer than a total number of the antennas. The UE may precode a sounding reference signal (SRS) using the approximated covariance matrix, and transmit the precoded SRS using the antennas associated with the transmit operations.
Patent EP-3634111-A1 (EP)
Inventor: WILLEMS Pieter
IPC: B24B3/36
Filed: 2018-05-12
Abstract: A method (100) for sharpening cutting knives (24) carried by a cutter drum (22) in a housing (46) of an agricultural vehicle (10) includes: initiating (S102) a knife sharpening protocol. The knife sharpening protocol includes: rotating (S 104) the cutter drum (22) while keeping a sharpening door (52) closed so an overpressure is created inside the housing (46), the sharpening door (52) shielding a sharpening stone (28) from the cutting knives (24) while creating the overpressure; opening (S106) a transition door (50) of the housing (46) below the cutter drum (22) to eject crop material through the open transition door (64); opening (S108) the sharpening door (52) to expose the cutting knives (24) to the sharpening stone (28) and closing (S108) the transition door (50); grinding (S110) one or more of the cutting knives (24) with the exposed sharpening stone (28); and closing (S112) the sharpening door (52) to shield the sharpening stone (28) from the cutting knives (24) after grinding (S110).
Patent EP-3652529-A1 (EP)
Inventor: RÜHL JÜRGEN
IPC: F01N3/20
Filed: 2018-04-26
Abstract: The invention relates to a device for measuring the concentration of a reductant, in particular urea, in a solution, comprising at tank housing (2) for storing the solution in an interior (2b) of the tank housing (2); a sensor device (1) for emitting a first measurement signal (30) into the interior (2b) in an emission direction (31) and for receiving reflections of the first measurement signal (30), the sensor device (1) being attached to an outer side (2a) of the tank housing (2) facing away from the interior (2b); a reflector component (3) in the interior (2b), having a first reflector (3a), which is arranged at a distance from the sensor device (1) in the emission direction (31) and reflects a first portion (30a) of the first measurement signal (30) back to the sensor device (1) against the emission direction (31), and having a second reflector (3b), which is spaced apart from the sensor device (1) in the emission direction (31) further than the first reflector (3a) by a distance (L) and which reflects a second portion (30b) of the first measurement signal (30) back to the sensor device (1) against the emission direction (31).
Patent EP-3625018-A1 (EP)
Title: Verfahren zum herstellen eines trockenfilms, walzvorrichtung, sowie trockenfilm und mit dem trockenfilm beschichtetes substrat
Inventor: ALTHUES HOLGER
IPC: B29L31/34
Filed: 2018-05-14
Abstract: Die vorliegende Erfindung betrifft ein Verfahren zum Herstellen eines Trockenfilms (3), bei dem eine Trockenpulvermischung durch eine Walzvorrichtung mit einer ersten Walze (2a) und einer zweiten Walze (2b) zu dem Trockenfilm (3) verarbeitet wird. Die erste Walze weist (2a) eine höhere Drehumfangsgeschwindigkeit als die zweite Walze (2b) auf und der Trockenfilm (3) wird auf der ersten Walze (2a) gelagert.
Patent EP-3635921-A1 (EP)
Inventor: FERNANDO REX EMMANUEL
IPC: H04L12/825
Filed: 2018-05-24
Abstract: A method is described and in some embodiments includes receiving at a network element a transmission control protocol ("TCP") packet with TCP options set on a link between a controller and a destination node; if the network element comprises a transit node, comparing a bandwidth value indicated in a TCP options field of the received TCP packet with an outgoing link bandwidth of the network element; if the bandwidth value indicated in the TCP options field is greater than the outgoing link bandwidth of the network element, updating the bandwidth value indicated in the TCP options field to be equal to the outgoing link bandwidth of the network element; and forwarding the TCP packet to a next network element. If the bandwidth value indicated in the TCP options field is not greater than the outgoing link bandwidth, the bandwidth value indicated in the TCP options field is not changed.
Patent EP-3638043-A1 (EP)
Title: Enzymprodukt mit beta-galaktosidase
Inventor: NAUMER CHRISTIAN
IPC: A23C9/12
Filed: 2018-06-15
Abstract: Die Erfindung betrifft ein Enzymprodukt umfassend ein beta-Galaktosidaseprodukt. Erfindungsgemäß ist vorgesehen, dass das beta-Galaktosidaseprodukt eine inaktive Arylsulfatase aufweist.
Patent EP-3638228-A1 (EP)
Inventor: MEHRLING THOMAS JORG
IPC: A61P35/00
Filed: 2018-06-13
Abstract: There is provided tinostamustine or a pharmaceutically acceptable salt thereof for use in the treatment of triple negative breast cancer (TNBC)to a patient in need thereof.
Patent EP-3654825-A1 (EP)
Inventor: SCHLICKER ANDREAS
IPC: A61B1/267
Filed: 2018-07-02
Abstract: The Invention relates to a medical device (1) for oral procedures, particularly for use in oral intubation and fixation procedures, comprising at least one protective device (2) for teeth, the protective device (2) comprising the a rigid support component (3), and at least one push button (4), arranged at the support component (3), wherein each of the at least one the push button (4) comprises a rigid surface (42) that is facing towards the teeth, when the medical device (1) is applied orally, wherein the support component (3) is configured such that each of the at least one push button (4) is displaceable separately relative to the support component (3) between a first position and a second position.