baber/WOPTO huggingface dataset:
Patent AU-2013203689-B2 (AU)
Title: Antigen Binding Proteins to Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9)
Inventor: SHAN BEI
IPC: A61P3/06
Filed: 2013-04-11
Granted: 2016-08-11
Abstract: Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an 5 antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. WO 2009/026558 PCT/US2008/074097 1-----------------------------------------------50 PCSK9parent (1) OZUNUGOYEiMIIAj '5EdGLAAP$1k5G5A~'iFRIKdPWESPG3YVV PCSK9mutants (1) R _1iRRRR RR FiliRdl lPWfi PdlYVV 51--- pro domain ------------------------------ 100 PCSK9parent (51) VNIIiIT LN NiTKII~if9FINGLLPGFLVf§fd PCSK9mutants (51) V-'Lj lKS! S TgF LKlIAil E-li TKIIAlFiGLLPGFLMEliF L 101-------------------=======50 PCSK9parent (101) ILELAILf LMNiUdYIEEDSSVFISIFINIlEItIPPRYRAf0EidPidGGI4V PCSK9mutants (101) EIL L YEI 1 IlPPRYR lIPIGGV 151================================ -------=== 200 PCSK9parent (151) E EAS CDSI-GTHL PCSK9mutants (151) EVYLLD'II|RRRH|EEEIDGRVRRRERRRERRRRRRERRR CDRqGTHL 201===---=============---=----------= = -====250 PCSK9parent (201) AGVVSG fAGVAINgfMRSI NVLNdGNGtVSGTLIGLEINI!NZ5~QvdB~9 PCSK9mutants (201) AGVVSGFPAGVA lidNlMRSlVLNClG1GlVSGTLIGLElR S P 251================= catalytic domain =========300 PCSK9parent (251) 7PLVVLLPLAGYSIVLtACQ RLIN GVVLVTAAGNF1 DDAC YSPA2A PCSK9mutants (251) 'PLVVLLPLAdlYSEVL lAdARLAEGVVLVTAAGNEEDDACRYSPARA 301============================================------350 PCSK9parent (301) PEVITVGATNQDQP TIGTI4GTNFGRCVDLFAPGEdIIGAS8CSC5' PCSK9mut ants (301) PEVI TVGA TNIRNRP(PMiiliGPGTNFGRCVDLFAPGl 9I I GAS$1 CSI Cli 351-= = = = = = = = = = == = = = = = = = = = = 400 PCSK9parent (351) 5 GSAAVGAIMjA5ILiAIL~ SK9IEEF PCSK9mutants (351) |PSGTAHAI I 401===------------------------------------------450 PCSK9parent (401) INININTPI LVA LPP5TN SG LFCRTVWSS WSRIbAl CAB PCSK9mutants (401) '__RRTALVALPPRRRRRRLFCRTWIS RRRECB 451--------------------------------------------500 PCSK9parent (451) EELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGP2GVYAIARCCLLP PCSK9mutants (451) EELLSCSSFSRSGKRRGERMERQGGKLVCRAHNR9GRCGVYAIARCCLLP 501-------------- v domain ------------------------ 550 PCSK9parent (501) QANCSVHdAPPZEAIN GTI-iViSfdQHQ GHVLTGCSSHVEfldG'IKPPIMLR PCSK9mutants (501) QACSViiAPPA lIiGII Cl liGHVLTGCSSHailIlGi KPFliLR 551---------------------------------------------------600 PCSK9parent (551) PINGdNQCVGHREASIHASCCHAPGLECkVKEIIPAVQEidVTPfCIZGW PCSK9mutants (551) PFIPlQCVGHREASIHASCCHAPGLEC(RRR IPAi ElVT\lCfGW 601--------------------------------------------650 PCSK9parent (601) TLTGCSALPGTSHVLGAYAIMDNTCVVR$NDVSTTGSTSEIEAVTAVAICCN PCSK9mutants (601) TLTGCSALPGTSHVLGAYAliDNTCVVRD ER _ V A 651 --------- 680 PCSK9parent (651) SPHLAQASQELQGSSDYKDDDKHHHHHHHH (SEQ ID NO:303) PCSK9mutants (651) S&HLAQASQELQGSSDYKDDDKHHHHHHHH (SEQ ID NO:304)
Patent AU-2013205336-B2 (AU)
Title: Multi-lumen central access vena cava filter apparatus and method of using same
Inventor: ANGEL LUIS F
IPC: A61B17/22
Filed: 2013-04-11
Granted: 2016-03-10
Abstract: A method for capturing thrombus within a blood vessel, comprising the steps of: introducing a multi-lumen catheter having a filter member coupled thereto; deploying the multi lumen catheter within a blood vessel such that the filter has an enlarged diametric opening that 5 opens facing a patient's blood flow; infusing a fluid through at least one lumen in the multi lumen catheter in communication with at least one infusion port passing through the multi-lumen catheter and open to an inner spatial area bounded by the filter member.
Patent AU-2013212690-B2 (AU)
Title: Tubular anchoring system and a seat for use in the same
Inventor: XU YINGQING
IPC: E21B33/124
Filed: 2013-01-03
Granted: 2016-11-10
Abstract: A tubular anchoring system includes a first frustoconical member. Slips in operable communication with the first frustoconical member are radially expandable into an anchoring engagement with a structure in response to longitudinal movement relative to a frustoconical surface of the first frustoconical member. A collar in operable communication with the first frustoconical member is radially expandable into sealing engagement with the structure in response to longitudinal movement relative to a second frustoconical member. A seat in operable communication with the first frustoconical member having a surface configured to be sealingly engagable with a plug runnable thereagainst, is configured and positioned relative to the collar to aid the seat in maintaining a radially expanded configuration against a pressure differential formed across the seat when plugged.
Patent AU-2013213619-B2 (AU)
Title: Blood filter, system and use of a blood filter or system
Inventor: ZAMBIANCHI LAURA
IPC: B01D39/16
Filed: 2013-01-24
Granted: 2016-12-01
Abstract: The invention relates to a blood filter, a system comprising a blood filter and the use of a blood filter or system for the removal of substances from whole blood or blood components. According to the invention, a blood, filter comprises an inlet (2), an outlet (3) and at least first fibres disposed between the inlet (2) and the outlet (3) for filtering a fluid being communicated between the inlet (2) and the outlet (3), wherein each of the first fibres comprises at least one groove extending in the longitudinal direction of the fibre.
Patent AU-2013222044-B2 (AU)
Title: Locking instrument assembly
Inventor: DEES JR ROGER RYAN
IPC: A61B17/15
Filed: 2013-09-02
Granted: 2015-10-29
Abstract: H:\txb\Interwoven\NRPortbl\DCC\TXB\5435858_1.doc - 2/9/13 A locking instrument assembly for use in conjunction with an intramedullary device is disclosed. The locking instrument assembly includes an inner collet, an outer body, and a knob. The inner collet has a collar and a fastener member. The knob engages the fastener member to press the outer body against the collar. As the knob mates with the fastener member, the collar applies a clamping force to the intramedullary device.
Patent AU-2013231166-B2 (AU)
Title: Systems and methods for distributing power in a vehicle
Inventor: KUMAR AJITH KUTTANNAIR
IPC: B60L50/14
Filed: 2013-09-24
Granted: 2016-11-24
Abstract: SYSTEMS AND METHODS FOR DISTRIBUTING POWER IN A VEHICLE Various systems and method for distributing electrical power are provided. In one embodiment, a system includes a first inverter coupled to an electrical bus, a second inverter coupled to the electrical bus, a filter including a first inductor and a second inductor, and a transfer switch circuit coupled between the first inverter and the second inverter and a load. The transfer switch circuit is configured to transfer power from the first inverter through the first inductor to the load and transfer power from the second inverter through the second inductor to the load in a first mode of operation. The transfer switch circuit is further configured to transfer power from the first inverter through the first inductor and through the second inductor to the load in a second mode of operation. < Cni col I ---------------- C:) (D --------------------- CD CD -------- --------- --------- < C 4 C'4 ----------- --- ----------- 0: ui LL co C"i r r" C:) < C"i orf --------------------------- El -F 77 d ui R UL ct uj > --F 77 z 0 TV -------- ------- rl T --- co C:) ---------- c:) kljl , +
Patent AU-2013256788-B2 (AU)
Title: Rubber formulations including graphenic carbon particles
Inventor: MARTIN JUSTIN J
IPC: C08K3/00
Filed: 2013-04-15
Granted: 2015-08-06
Abstract: Rubber formulations comprising a base rubber composition, graphenic carbon particles, and non-conductive filler particles such as silica are disclosed. The formulations possess favorable properties such as relatively low surface resistivities, and are useful for many applications such as tire treads.
Patent AU-2013343677-B2 (AU)
Title: A machine for emulsifying fuel oils with water
Inventor: CIARALLA ENRICO
IPC: F02M25/022
Filed: 2013-11-06
Granted: 2018-03-08
Abstract: The present invention relates to a machine for emulsifying fuel oils with water, which comprises a hermetically closed stator case (2) a cylindrical drum (1) contained and rotating inside said case (6), being driven by a shaft (6) and provided with a regularly spaced radial series of centrifugal conduits (9) joined in proximity of the peripheral end (9a) with channels (10) with lower diameter, adapted to convey mixture into the passage (11) interposed between the lower wall (1 b) of the drum (1) and the internal wall (5b) of the lower cover (5) of the case (2).
Patent AU-2013362119-B2 (AU)
Title: Haemodiafiltration method
Inventor: TSCHULENA ULRICH
IPC: A61M1/36
Filed: 2013-12-19
Granted: 2017-06-15
Abstract: The invention relates to a device for haemodiafiltration comprising an extracorporeal circulation (10) for receiving blood to be cleaned and comprising a haemodialyser and/or haemofilter (20) which is connected to the blood circulation (10), said blood circulation (10) having at least one respective supply line (12, 14) located upstream and downstream of the haemodialyser and/or haemofilter (20), for supplying a substitution fluid. The invention is characterised in that the device also comprises measuring devices for recording the transmembrane pressure and/or haematocrit (HKT) and/or blood density, the measuring devices being connected to a control unit (100) for controlling one or more of the transmembrane pressure, and/or haematocrit (HKT) and/or blood density and said control unit (100) being constructed in such a way that the control is carried out (13, 15) with the aid of at least one of the infusion speeds (Q
Patent AU-2013364003-B2 (AU)
Title: Agricultural input selection systems, methods and apparatus
Inventor: SAUDER TIMOTHY
IPC: A01C7/00
Filed: 2013-12-21
Granted: 2017-11-09
Abstract: Systems, methods and apparatus for applying varying agricultural inputs in accordance with a prescription map. The system includes a plurality of input sources each containing different agricultural inputs. A variety selector selectively places the different inputs from the plurality of input sources in communication with a meter for dispensing the inputs in accordance with the prescription map to minimize prescription errors.
Patent AU-2014202354-B2 (AU)
Title: Pressure test containment vessel
Inventor: MANN MICHAEL L
IPC: G01N3/12
Filed: 2014-04-30
Granted: 2016-07-21
Abstract: A portable containment vessel to perform a pressure test to a test specimen includes a base skid, a ballistic outer enclosure connected to the base skid and comprising a plurality of walls, a door, and a lock to maintain the door in a closed position, a sample tray configured to support the test specimen, wherein the sample tray is operable through a doorway of the ballistic outer enclosure between a retracted position and an extended position, a containment fluid to surround the test specimen while a pressurized test fluid is applied to the test specimen, and a sensor to indicate a failure of the pressure test. S-11 104Fl 102D 1--- 13.2 110OA 132 126 7 16104A
Patent AU-2014202968-B2 (AU)
Title: Barrier
Inventor: MOSS CRAIG JUSTIN
IPC: E04H17/00
Filed: 2014-06-02
Granted: 2018-08-09
Abstract: Abstract A barrier comprising a plurality of barrier members, each barrier member having a central body and a plurality of arms extending outwardly therefrom; and connectors provided at the ends of each of the arms of the barrier member, the connectors are 5 provided to engage each arm of a barrier member with an arm of a further barrier member such that the connected barrier members form a mesh structure. The barrier members comprise a body portion having an aperture and are adapted to be pivotally attached to each other. () b E Lg 15-
Patent AU-2014203034-B2 (AU)
Title: Stable pharmaceutical composition and methods of using same
Inventor: MANKU MEHAR
IPC: A61K31/20
Filed: 2014-06-04
Granted: 2016-09-15
Abstract: A pharmaceutical composition comprising at least 95% EPA enclosed in a capsule shell, wherein the composition has a baseline peroxide value not greater than 5 Meq/kg and upon storage of the composition at 25'C and 60% RH for a period of 6 months, the composition has a second peroxide value not greater than 8 Meq/kg.
Patent AU-2014203883-B2 (AU)
Title: IEEE 802.11 communication utilizing carrier specific interference mitigation
Inventor: CLEGG MICHAEL
IPC: H04W72/04
Filed: 2014-01-07
Granted: 2015-07-30
Abstract: Wireless communication under IEEE 802.1 1 standards utilizing carrier specific interference mitigation where an AP or UE employs an ultra-wideband tuner to evaluate available spectrum between several communication bands. Rather than being constrained to communicate in a single communication band, the AP and UEs may utilize more than one communication band to communicate with one another. In doing so, the AP and UE search across several bands and measure interference on a carrier-by-carrier basis across those bands. Either of the AP and UE may select a cluster of carriers for communication, where the cluster of carriers may comprise 1) contiguous carriers in a single sub-channel, 2) contiguous carriers spanning across more than one sub-channel, 3) discontinuous carriers in a single sub-channel, or 4) discontinuous carriers spanning across more than one sub-channel. The mapping between a cluster and its carriers can be fixed or reconfigurable.
Patent AU-2014204344-B2 (AU)
Title: Method for obtaining immuno-stimulatory dendritic cells
Inventor: HENCO KARSTEN
IPC: A61K35/15
Filed: 2014-01-02
Granted: 2017-04-06
Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
Patent AU-2014213963-B2 (AU)
Title: Device and method for measuring plant growth conditions
Inventor: DE GROOT JACOB FRANK
IPC: G01N27/22
Filed: 2014-02-07
Granted: 2017-09-21
Abstract: A device (10) and method are provided for measuring the plant growth conditions within a substrate. A first and a second linear arrays of probes (16, 18) are used, allowing multiple measurements of properties of the substrate. Using multiple measurements at different levels in the substrate and then combining these multiple measurements, allows plant growth conditions to be accurately derived.
Patent AU-2014221241-B2 (AU)
Title: Pedestrian tile, replaceable tile section and/or resilient dome structure
Inventor: SZEKELY KENNETH EUGENE
IPC: E01C5/00
Filed: 2014-09-04
Granted: 2018-09-20
Abstract: Abstract A detectable warning tile system has a tile base with an upper surface and a lower surface. The upper surface has a plurality of upward projections therefrom. The tile base has two side edges for alignment with corresponding side edges of other tiles, and front and rear edges. An area of the upper surface of the tile base is formed free of the detectable warnings and may include a trough into or over which a replaceable tile section may be placed. The tile base and/or replaceable tile section may be configured to receive one or more individually- installable detectable warnings.
Patent AU-2014225963-B2 (AU)
Title: Echolucent guidewire tip
Inventor: FISCHER FRANK J
IPC: A61B8/12
Filed: 2014-03-04
Granted: 2017-03-30
Abstract: A medical device includes a guidewire with a lumen, a plastic tip, and a removable mandrel. The medical device has echogenic properties which can be altered between an echogenic state and an echolucent state by evacuating the lumen and applying a liquid or gas within the lumen.
Patent AU-2014228405-B2 (AU)
Title: Cancer vaccines and methods of treatment using the same
Inventor: WEINER DAVID
IPC: A61K48/00
Filed: 2014-03-14
Granted: 2017-05-11
Abstract: Disclosed are vaccine compositions comprising one or more nucleic acid encoding one or more amino acid sequence(s) selected from the group consisting of amino acid sequences of tyrosinase (Tyr), tyrosinase-related protein 1 (TYRP1 ), tyrosinase-related protein 2 (TYRP2), melanoma-associated antigen 4 protein (MAGEA4), growth hormone release hormone (GHRH), MART-1/melan-A antigen, cancer testis antigen NY-ESO-1, cancer testis antigen NY-ESO-2, preferentially expressed antigen in melanoma (PRAME), Wilms' tumor 1 (WT1), and human telomerase reverse transcriptase (hTERT). The vaccine compositions can further comprise a nucleic acid encoding one or more other antigens including prostate specific antigen (PSA). Further disclosed are methods of preventing or treating cancer in a subject in need comprising administering to the subject a vaccine composition comprising a particular number of cancer antigens for treating or preventing a particular cancer.
Patent AU-2014229072-B2 (AU)
Title: Multi-chamber injection device
Inventor: TENNICAN PATRICK O
IPC: A61M5/19
Filed: 2014-03-14
Granted: 2019-01-24
Abstract: A multi-chamber injection device includes multiple syringes. The multiple syringes may be arrayed in a circular, linear, or other format. In some implementations, a needle, port, or similar may be shared by all the syringes in configuration that allows only one syringe to deliver contents at a time while blocking the other syringes from delivering their respective contents. In some implementations, the syringes may be all stored in the same container. One or more of the chambers of a multi-chamber injection device may be preloaded with medication. Different medications may be loaded into different chambers. The medications may be selected to treat the same medical condition.
Patent AU-2014236348-B2 (AU)
Title: Combination therapy for treating cancer
Inventor: KLAUS CHRISTINE
IPC: C07D487/04
Filed: 2014-03-14
Granted: 2018-05-10
Abstract: The present invention relates to compositions comprising inhibitors of human histone methyltransferase DOTIL and one or more therapeutic agents, particularly anticancer agents, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
Patent AU-2014246866-B2 (AU)
Title: Kinase inhibitor
Inventor: FYFE MATTHEW COLIN THOR
IPC: A61P29/00
Filed: 2014-04-01
Granted: 2018-05-10
Abstract: There is provided a compound of formula (I), which compound has antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases, e.g., Src and Lck) and has use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
Patent AU-2014256379-B2 (AU)
Title: Material handling machine
Inventor: HILL EDWARD
IPC: B66F9/12
Filed: 2014-10-30
Granted: 2017-10-26
Abstract: Abstract The present invention relates to a material handling machine including an implement manoeuvring apparatus. The material handling machine has a front part which is articulated via a pivot arrangement to a rear part. The rear part includes an operator cab, an engine and rear ground engaging wheels. The front part includes a front left ground engaging wheel and a front right ground engaging wheel which is positioned on the right hand side of the front part opposite the front left ground engaging wheel. The implement manoeuvring apparatus is Mounted on the front, the front of which can be mounted a materials handling implement, wherein the apparatus is defined by a set of links interconnected by pivots. 0* Na6 t ell^
Patent AU-2014264204-B2 (AU)
Title: A method and system for communicating banking-related security messages
Inventor: VAN DER WALT TJAART
IPC: G06F15/16
Filed: 2014-05-09
Granted: 2019-04-18
Abstract: A method of communicating banking-related security messages, the method including receiving, by a mobile network messaging system (202), a security message (120) from a banking system (104), the security message containing a temporary security code (e.g. a one-time-PIN) typically used for a financial transaction and forwarding the security message (12) to a mobile device (108) of a user. The method includes monitoring outgoing messages from the mobile device (108) for a pre-determined time period after the security message was forwarded and intercepting (220, 420) any outgoing message (122, 322) during the time period if the message (122, 322) contains the security code.
Patent AU-2014274748-B2 (AU)
Title: Patient-matched apparatus and methods for performing surgical procedures
Inventor: FREY GEORGE
IPC: A61B5/05
Filed: 2014-06-06
Granted: 2018-03-01
Abstract: A system and method for developing customized apparatus for use in one or more surgical procedures is disclosed. The system and method incorporates a patient's unique anatomical features or morphology. According to a preferred embodiment, the customized apparatus comprises a plurality of complementary surfaces. Thus, each apparatus may be matched and oriented around the patient's own anatomy, and may further provide any desired axial alignments or insertional trajectories. In an alternate embodiment, the apparatus may further be aligned and/or matched with at least one other apparatus used during the surgical procedure.
Patent AU-2014289376-B2 (AU)
Title: Device for frothing a liquid
Inventor: NOORDHUIS JOEKE
IPC: A47J31/44
Filed: 2014-07-07
Granted: 2018-12-20
Abstract: A device (2, 3, 4, 5, 6, 7, 8) for frothing a liquid (15) is presented, in particular for providing two or more streams of froth in parallel. The device comprises: a steam generator (10) for generating a stream of steam (13), a steam splitter (30) for splitting the stream of steam (13) into a first sub-stream of steam (33A) and a second sub-stream of steam (33B), wherein the first sub-stream of steam (33A) is provided at a first steam outlet (32A) and the second sub-stream of steam (33B) is provided at a second steam outlet (32B), a first frothing unit (11A) having a first liquid inlet (14A) and a first steam inlet (16A), a second frothing unit (11B) having a second liquid inlet (14B) and a second steam inlet (16B), wherein the first steam outlet (32A) of the steam splitter (30) is connected to the first steam inlet (16A) of the first frothing unit (11A) and the second steam outlet (32B) of the steam splitter (30) is connected to the second steam inlet (16B) of the second frothing unit (11B). In a further aspect a coffee machine (50) comprising a coffee brewing unit (51) and the device for frothing a liquid is presented.
Patent AU-2014325697-B2 (AU)
Title: Burner and coal upgrading plant
Inventor: YOKOHAMA KATSUHIKO
IPC: F23D17/00
Filed: 2014-07-17
Granted: 2017-03-30
Abstract: A burner equipped with: a tubular first outer tube (20); a diffuser (21) arranged on the inside of the first outer tube (20) and having an inner circumferential surface the diameter of which gradually increases in a first direction; first gas nozzles (22) that supply a first gas toward the first direction in a region on the outside of the diffuser (21) in the radial direction; second gas nozzles (23) that are arranged adjacent to the first gas nozzles (22) in the circumferential direction of the first outer tube (20), and that supply a second gas toward the first direction in the region on the outside of the diffuser (21) in the radial direction; and an ignition torch (24) that ignites the second gas and/or the first gas.
Patent AU-2014348629-B2 (AU)
Title: Completion systems including an expansion joint and a wet connect
Inventor: BISHOP DAVID S
IPC: E21B17/00
Filed: 2014-11-13
Granted: 2018-05-17
Abstract: A production string for use in a wellbore is disclosed that in a non-limiting embodiment includes a lower section that includes a first tubular having a first connection device at a top end thereof, and an upper section that includes a second tubular that sealingly slides against the first tubular, a second connection device associated with the second tubular configured to engage with the first connection device, and an expansion joint above the second tubular.