baber/WOPTO huggingface dataset:
Patent DE-69720965-T2 (DE)
Inventor: THOMAS ANDREW PETER
IPC: A61K31/54
Filed: 1997-02-10
Granted: 2004-02-05
Abstract: The invention relates to quinazoline derivatives of formula (I)wherein: Z represents -O-, -NH- or -S-; m is an integer from 1 to 5; R1 represents hydrogen, hydroxy, halogeno, nitro, trifluorometlyl, cyano, C1-3alkyl, C1-3alkoxy, C1-3alkylthio or NR5R6 (wherein R5 and R6, which may be the same or different, each represents hydrogen or C1-3alkyl); R2 represents hydrogen, hydroxy, halogeno, methoxy, amino, or nitro; R3 represents hydroxy, halogeno, C1-3alkyl, C1-3alkoxy, C1-3alkanoyloxy, trifluoromethyl, cyano, amino or nitro; X1 represents -O-, -CH2-, -S-, -SO-, SO2-, -NR6-, NR8CO-, -CONR9-SO2NR10- or -NR11SO2-, (wherein R7, R8, R9, R10 and R11 each represents C1-3alkyl, C1-3alkoxyC2-3alkyl); R4 represents a group which is alkenyl, alkynyl or optionally substituted alkyl, which alkyl group may contain a heteroatom linking group, which alkenyl, alkynyl or alkyl group may carry a terminal optionally substituted 5 or 6 membered saturated carbocylic or heterocyclic group; and salts thereof, processes for their preparation, pharmaceutical compositions containing a compound of formula (I) or a pharmaceutically acceptable salt thereof as active ingredient the compounds of formula (I) and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent DE-69725869-T2 (DE)
Inventor: MEYER PAUL
IPC: A23L27/24
Filed: 1997-12-29
Granted: 2004-05-19
Abstract: A full moisture shelf stable noodle product having a dry matter content of from 30 to 45% by weight, having a pH of from 3.7 to 4.5 and comprising a cooked flour or semolina of a starchy plant, softened water, a cooked starch, an ionic gelling agent, an emulsifier, a cation which has formed a gel with the ionic gelling agent, an acid and an oil.
Patent DE-69730598-T2 (DE)
Inventor: EKHOLM ROLF
IPC: F04D7/00
Filed: 1997-04-15
Granted: 2005-09-29
Abstract: System for feeding a suspension, preferably a suspension of chips in a liquid carrier, to a pressurized vessel in a cellulose pulp mill, which system comprises at least one pump (25, 26) between a low-pressure part and the pressurized vessel for driving the suspension from the low-pressure part into the vessel, which pump is of the type which comprises a number of parallel discs (40, 42) which are held together to form a stack (39) and rotate in a pump chamber (36) in a pump housing about a common axis of rotation, with the spaces (46) between the discs being greater than the particles in the suspension, and with an axial inlet and a tangential outlet for the suspension. The invention also includes a pump and an apparatus unit which are intended to form part of the system.
Patent DE-69730817-T2 (DE)
Inventor: SCHERZ WIARD
IPC: A61K31/34
Filed: 1997-01-30
Granted: 2005-02-03
Abstract: A compound having the structure:   <IMAGE>   wherein (a) n is from 1 to about 3; (b) X is selected from the group consisiting of O, S, SO, or SO2; (c) Y is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 carbon atoms, or the Y's are bonded together to form an alkanyl ring having from 3 to about 7 atoms; (d) Z is hydrogen or straight, branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; (e) W is O or S; and (f) R1, R2 and R3 are independently hydrogen, straight, branched or cyclic alkyl having from 1 to 10 carbon atoms, aryl, heterocyclyl, heteroaryl, hydroxy, or alkoxy; or R1, R2 or R3 may be bonded to form one or more rings each ring having from 3 to about 7 atoms wherein from 1 to 3 atoms may be heteroatoms. pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.
Patent DE-69731320-T2 (DE)
Inventor: CONTAXIS WILLIAM
IPC: F02M37/32
Filed: 1997-08-06
Granted: 2006-02-23
Abstract: An additive dispensing apparatus for a fluid system is disclosed which includes a head having a body portion adapted and configured for fluid communication with the fluid system and having a flow path extending therethrough. A fluid inlet portion of the flow path defines a relatively high pressure region and a fluid outlet portion of the flow path defines a relatively low pressure region. A canister is operatively associated with the body portion and structure is provided for facilitating fluid communication between the fluid inlet portion and the interior of the canister. A collapsible container is disposed within the canister for containing a liquid additive for dispensement into the fluid system and structure is provided for facilitating fluid communication between the collapsible container and the fluid outlet portion, whereby the differential pressure between the interior of the canister and the interior of the collapsible container effectuates a proportional dispensement of liquid additive into the fluid system.
Patent DE-69736441-T2 (DE)
Inventor: OGNYANOV ILIYA
IPC: A61P25/24
Filed: 1997-05-29
Granted: 2007-07-19
Abstract: The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof.
Patent DE-69825745-T2 (DE)
Inventor: VILLA MARCO
IPC: C07B63/00
Filed: 1998-05-04
Granted: 2005-08-18
Abstract: A method for the removal of heavy metals from solutions of organic compounds by treatment with cysteine or with an N-acylcysteine is described. Organic compounds with a content of heavy metal, for example palladium, particularly low and suitable for the preparation of compounds with pharmacologic activity can be isolated from the resultant solutions.
Patent DE-69828315-T2 (DE)
Inventor: LUK SYDNEY
IPC: C22C33/02
Filed: 1998-05-15
Granted: 2005-06-09
Abstract: The present invention concerns an improved metallurgical powder composition comprising a major amount of an iron based metal powder and a minor amount of a particulate inorganic oxide having an average particle size below 500 nm.
Patent DE-69911001-T2 (DE)
Inventor: BECK G
IPC: A44B19/26
Filed: 1999-04-06
Granted: 2004-04-01
Abstract: A foldable plastic slider for straddling relation with a profiled plastic zipper. The straddling slider for closing or opening the zipper by movement therealong, comprising: a transverse support member including opposing sides, a pair of legs depending from the opposing sides of the support member, and a pair of wings hingedly attached to the opposing sides. Each wing has an opening for receiving its respective leg, and each wing has a cored out cross piece. The cored out cross piece has a solid ramp latch. The wings are folded relative to the support member and the latches engage the legs to assemble the slider on the zipper in a closed sidewall position.
Patent DE-69912380-T2 (DE)
Inventor: SUDO MORIHIRO
IPC: A61M5/315
Filed: 1999-06-11
Granted: 2004-08-12
Abstract: In a plunger for a syringe including a laminated piston which is provided with a shaft with a female thread and which is slidably inserted into a barrel and a rod having a male thread which can be screw-engaged in the threaded hole of the laminated piston, the axial length T of the crest of the female thread and the root of the male thread which engages with the female thread is greater than the axial length t of the root of the female thread and the crest of the male thread. <IMAGE>
Patent DE-69915367-T2 (DE)
Inventor: NILSSON AGNE
IPC: F24F3/16
Filed: 1999-12-01
Granted: 2005-03-17
Abstract: A method and a device for ventilation of a room with walls (11) and a ceiling (10), clean air being conducted at least to a portion of the room from the ceiling through a first air stream (12), and air being exhausted through first discharge openings (15) provided in the walls (11) of the room. Air contained in a second air stream (13) along at least one wall (11) is exhausted from the room through at least a second discharge opening (32) provided above the walls of the room outside of a designated work area in the room. The supplied is conducted towards a sloping flow director (20) arranged at the second exhaust opening (32).
Patent DE-69918575-T2 (DE)
Inventor: ADRIANSENS ERIC
IPC: B67C3/22
Filed: 1999-12-07
Granted: 2005-09-01
Abstract: A filling machine (38) includes at least one filling tube (22), whereby a product flows through the tube, which tube is placed opposite the opening of a receptacle (12) that is to be filled. The filling tube is accommodated in a fixed housing that is joined to a support (34) for the filling tube; the housing possesses an orifice (48) whereby the filling tube is placed opposite thereto and the housing also includes a moveable obturating flap (50) that closes the orifice and seals the housing when in a closed position. The machine includes structure that enables a cleaning agent to be circulated inside the housing.
Patent DE-69920457-T2 (DE)
Inventor: KVEEN L
IPC: A61F2/915
Filed: 1999-07-02
Granted: 2005-08-25
Abstract: A radially expandable stent comprising a plurality of spaced band-like (116) elements and intersecting links is disclosed. The band-like elements have a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks (124) and troughs (128) taking a generally longitudinal direction along the cylinder such that the waves in the band-like elements open as the stent is expanded from a first diameter to a second diameter. <IMAGE>
Patent DE-69920946-T2 (DE)
Inventor: BISRAT MIKAEL
IPC: A61P29/00
Filed: 1999-11-22
Granted: 2005-08-25
Abstract: The invention provides a process for preparing essentially crystalline particles containing a substance in solvated form, by dissolving the substance in a first solvent, introducing the solution and a supercritical or subcritical fluid into an apparatus, wherein the fluid contains an anti-solvent and a second solvent, which is water. Preferably, the anti-solvent is carbon dioxide which is totally saturated with the second solvent, which is water. The invention further provides formulations comprising particles produced according to the present process containing one or more pharmacologically active substances and one or more pharmaceu-tically acceptable excipients, use of said formulations in the treatment of an allergic and/or inflammatory condition of the nose or lungs and methods for treatment of such conditions.
Patent DE-69926867-T2 (DE)
Inventor: PREVOTS FABIEN
IPC: C12N15/31
Filed: 1999-12-28
Granted: 2006-06-08
Abstract: The invention relates to a DNA sequence capable of being transferred by conjugation, which comprises the sequence SEQ ID No: 2. The invention further relates to the use of this DNA sequence and to a method of carrying it out.
Patent HU-E027025-T2 (HU)
Title: Non-cytotoxic protein conjugates
Inventor: FOSTER KEITH
IPC: C12N15/62
Filed: 2005-12-01
Abstract: A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described.
Patent HU-E033863-T2 (HU)
Title: Process for preparing carbamoylpyridone derivatives and intermediates
Inventor: WANG HUAN
IPC: A61K31/44
Filed: 2011-03-22
Abstract: The present invention relates to the preparation of carbamoylpyridone derivatives and intermediates.
Patent HU-E029080-T2 (HU)
Title: MMP activated vascular disrupting agents
Inventor: GILL JASON
IPC: C07K7/06
Filed: 2008-03-27
Abstract: The present invention relates to compounds, and pharmaceutically acceptable salts thereof, comprising a vascular disrupting agent (VDA) associated and a MMP proteolytic cleavage site. The compounds are useful in the treatment of cancer.
Patent HU-E033418-T2 (HU)
Title: A method and apparatus for muting signaling in a wireless communication network
Inventor: KAZMI MUHAMMAD
IPC: H04L5/00
Filed: 2011-03-03
Abstract: In one aspect, the present invention provides a simple method of signaling reference signal muting information to receiving radio equipment (50), such as items of user equipment (UEs) (20). The reference signals may be positioning reference signals and/or cell-specific reference signals, for example. In one or more embodiments, the present invention proposes a general solution whereby the receiving radio equipment (50) is informed not only on whether muting is used in general in a cell, but also the particular timing and formatting of such muting. Further, the contemplated method provides for the use of dynamic muting patterns, and thus avoids the need for statically defined muting patterns, and provides for coordinated muting control, across two or more network cells. In at least one embodiment, static or less dynamic aspects of the muting configuration is signaled via higher-layer signaling, while lower-layer signaling is used to signal more dynamic aspects of the muting configuration.
Patent SI-1598249-T2 (SI)
Title: Sway control brake for trailers
Inventor: GERHARD BECK
IPC: B60T13/74
Filed: 2005-05-12
Abstract: The trailer (1) can be fitted with a v-shaped towing unit (3) joined to the vehicle with a ball and socket connection. An anti-roll unit (13) assembled of the brake rods and at least one operating cable joined to the rods with a swingle tree is attached to the axle (8) of the trailer (1). The lateral motion of the trailer (1) is monitored by a sensor element and suppressed by an electrically operated control unit designed as a pulling or pushing rod attached to the center of the brake impulse transmitting device.
Patent TR-200100110-T2 (TR)
Inventor: RAMALINGAM BALASUBRAMANIAM
IPC: C08G59/42
Filed: 1999-05-19
Abstract: Formulations containing reaction products of epoxy compounds with active hydrogen-containing compounds such as amines and carboxylic acids having unique adhesive and other properties are disclosed. Laminates of various films and/or foils made with such formulations have desirable properties for packaging of food and other products.
Patent TR-200101610-T2 (TR)
Title: Toprak set ve su geçirmezlik yöntemi.
Inventor: SCUERO ALBERTO
IPC: E02B3/10
Filed: 1999-12-06
Abstract: Su bendi, örnegin toprak ve/ya da kaya (A) gibi gevsek malzemeden imal edilmis bir gövd (11) ve su geçirmez bir tabaka zar (13) ve zarin (13) en az bir tarafinda gevsek malzemeden (B) su geçirgen bir bölgeden meydana gelen ve su bendi gövdesi (11) ile ayni eksende uzanan bir su bariyerinden (12) olusur. Söz konusu su geçirgen bölge bir izolasyon akiskani ile enjekte edilebilir ve zarin (13) delinmesinden kaçinmak ve su geçirmez zardaki (13) sorunlar nedeniyle meydana gelebilecek su sizintilarini gözlemek üzere tasarlanmistir.Su bariyeri (12), su bendinin gövdesi içinde  ya da yukari bakan yüzeye yakin bir yerde bulunabilir.
Patent TR-200200475-T2 (TR)
Inventor: SUGHRUE EDWARD L
IPC: C10G29/04
Filed: 2000-08-09
Abstract: Particulate sorbent compositions comprising a mixture of zinc oxide, silica, alumina and a substantially reduced valence nickel are provided for the desulfurization of a feedstream of cracked-gasoline or diesel fuels in a desulfurization zone by a process which comprises the contacting of such feedstreams in a desulfurization zone followed by separation of the resulting low sulfur-containing stream and sulfurized-sorbent and thereafter regenerating and activating the separated sorbent before recycle of same to the desulfurization zone.
Patent TR-200201145-T2 (TR)
Title: Hidromisin türevleri
Inventor: BRIGHTY KATHERINE ELIZABETH
IPC: C07D407/12
Filed: 2000-10-09
Abstract: Mevcut bulus formül (1'e ait bilesiklerle ve bunlarin farmasötik açidan kabul gören tuzlari, ön ilaçlar ve solvatlari ile ilgilidir; buradaki X,Y,V,W ,W ,Z  ve Z , burada tanimlandigi gibidir. Bulus, yukaridaki bilesikleri ihtiva eden farmasötik kompozisyonlarla ve yukaridaki bilesiklerin uygulanmasi suretiyle bakteriyel ve protozoal enfeksiyonlarin tedavi edilmesine yönelik metotlarla da ilgilidir.
Patent DE-602004004152-T2 (DE)
Inventor: CORNIER JEAN-PHILIPPE
IPC: H04W80/10
Filed: 2004-11-05
Granted: 2007-10-11
Abstract: In one embodiment, a scheme is provided for customization of a mobile communications device's data session retry mechanism in a wireless packet data service network (112). Upon detecting that a cause code (404) has been returned by a node (206, 208) disposed in a wireless packet data service network (112), a structure (400) is interrogated to determine if the cause code (404) is mapped to a flag (406) relating to the device's data session retry mechanism. Responsive to determining that the received cause code (404) is mapped as a critical cause code, the data session retry mechanism of the mobile communications device (116) is disabled so that further signaling messages towards the network are prevented.
Patent DE-602004004763-T2 (DE)
Inventor: ATTAR RASHID AHMED
IPC: H04J13/02
Filed: 2004-03-11
Granted: 2007-10-31
Abstract: An apparatus and a method enabling increased data throughput on the reverse link are disclosed.
Patent DE-602004005899-T2 (DE)
Inventor: CHIFFEY ANDREW FRANCIS
IPC: F01N13/00
Filed: 2004-12-14
Granted: 2007-12-20
Abstract: An exhaust system (10) for a lean burn internal combustion engine comprises a particulate filter (12) disposed between an inlet (18) and an outlet and means (14) for deflecting at least some exhaust gas flowing in the system away from entering the filter at a point immediately opposite the inlet.
Patent DE-602004009539-T2 (DE)
Inventor: PROLLIUS SVEN
IPC: G09F13/16
Filed: 2004-04-07
Granted: 2008-07-24
Abstract: The present invention provides a license plate assembly comprising a light source and a license plate suitable for back illumination, said license plate comprising  (i) a retroreflective sheet having on a base prismatic elements having lateral faces intersecting the base at base edges, wherein said prismatic elements are truncated having elevated edges and truncated surfaces that are transparent and bounded by the elevated edges of the prismatic elements and/or said retroreflective sheet comprises transparent separation surfaces between said prismatic elements, said separation surfaces being bounded by the base edges of said prismatic elements; (ii) and one or more indicia;  and said retroreflective sheet being arranged on said light source such that said prismatic elements of said retroflective sheet are facing the light source. <IMAGE>
Patent DE-602006000135-T2 (DE)
Inventor: MASUDA TAKAHIRO
IPC: H01H59/00
Filed: 2006-03-14
Granted: 2008-07-10
Abstract: A micro electromechanical relay opens and closes an electrical circuit by contact / separation between a fixed contact disposed on a base and a movable contact disposed on an actuator by driving of a movable electrode by electrostatic attraction by application of voltage between a fixed electrode disposed on the base and a movable electrode of the actuator. The actuator comprises a supporting portion disposed on the base, a beam portion extending in a cantilevered manner from the supporting portion, and a movable electrode and a movable contact elastically supported by the beam portion. The beam portion elastically supports, in order from the supporting portion end, the movable electrode and the movable contact. A slit is formed from the side of the supporting portion in the portion of the actuator connecting the beam portion and the movable electrode.
Patent DE-602006000217-T2 (DE)
Inventor: CAPORUSSO ALESSANDRO
IPC: B21D7/024
Filed: 2006-02-02
Granted: 2008-09-11
Abstract: A bending machine with a compact bend arm includes in a bend arm (4) being mounted on a rotating spindle (3) a cylinder which is fed with a pressured fluid through hoses (7) being part of a hydraulic circuit connected to a source of pressured fluid and of an electric circuit. Each of the hoses (7), which are side by side, comprises a curved section (7a) around the rotating spindle (3), the curved section (7a) being radiused at one end to a section (7b) parallel to the bend arm (4), and at the other end to a section (7c) directed to the rest of the bending machine, to which hoses (7) are retained. In the section (7b) parallel to the bend arm (4) the plurality of hoses (7) are clamped on a slider (9) slidable in a prismatic guide (10) which is provided in the bend arm (4).
Patent DE-602006000605-T2 (DE)
Inventor: ROWLEY JAMES
IPC: F16B7/02
Filed: 2006-03-31
Granted: 2009-04-02
Abstract: A mooring connector or pipeline recovery tool comprising a mandrel (10) around which is concentrically disposed a ball cage (11) having balls (12) protruding therefrom so that relative longitudinal movement of the mandrel (10) and ball cage (11) causes the balls to ascend ramped surfaces of the mandrel (10) thus to protrude outwardly through the ball cage (11). The conventional arrangement of balls in regular rows and columns is replaced by helical rows or random arrays of the balls thus to avoid excessive grooving and deformation of the wall of a receptor into which the connector is inserted.
Patent DE-3850593-T3 (DE)
Inventor: COSAND WESLEY L
IPC: A61K38/00
Filed: 1988-03-24
Granted: 2001-01-04
Abstract: Peptide sequences are disclosed which immunologically mimic proteins encoded by the env and gag regions of LAV-2, a retrovirus associated with AIDS. The peptide can be used in various specific binding assays to detect the presence of antibodies to LAV-2 in individuals previously exposed to the virus. The peptides enable one to distinguish the presence of antibodies to LAV-2 from antibodies to HIV-1.
Patent DE-60219075-T3 (DE)
Inventor: ANGELINI MARCO
IPC: F21K99/00
Filed: 2002-12-06
Granted: 2014-05-28
Abstract: There is provided a lighting module of the type having a solid-state light source, in particular a LED, a supporting plate, and a lens; the lens has a recess housing the light source; the lens is supported by and projects from the plate by means of supporting members carried by the lens and for fitting the lens directly to the plate; and the supporting members are formed in one piece with the lens, and are spaced apart and separated from one another by cooling windows.
Patent DE-69123981-T3 (DE)
Inventor: GUILD BRAYDON
IPC: A61K35/44
Filed: 1991-10-31
Granted: 2006-06-14
Abstract: Retroviral vectors are disclosed which include an insertion site for genes of interest and are capable of expressing high levels of the protein derived from the genes of interest in a wide variety of transfected cell types. Also disclosed are retroviral vectors lacking a selectable marker, thus rendering them suitable for human gene therapy in the treatment of a variety of disease states without the co-expression of a marker product, such as an antibiotic. These retroviral vectors are especially suited for use in certain packaging cell lines.