baber/WOPTO huggingface dataset:
Patent NZ-525096-A (NZ)
Title: Process and intermediates for the production of 7-substituted antiestrogens
Inventor: STEVENSON ROBERT
IPC: C07J41/00
Filed: 2001-10-09
Abstract: A process is disclosed for preparing an intermediate compound of formula (II), wherein R is hydrogen or a hydroxy protecting group; X is as defined in the specification; R1 is haloalkyl, alkyl, alkenyl, cycloalkyl, carboxyalkyl, alkoxycarbonylalkyl, aryl or arylalkyl; R2, R3, R4 and R5 are organic groups as defined in the specification, which process comprises aromatisation of a compound of formula (III): where R1, R2, R3, n X and R5 are as defined in relation to formula (II) and R4' is a group R4 or a precursor group thereof, and thereafter if necessary or desired, carrying out one or more of the following steps: (i) removing any hydroxy protecting groups R; (ii) converting a precursor group R4' to a group R4, or where R4' is a group R4, converting it to a different such group. Compounds obtained are useful intermediates for example in the preparation of pharmaceutical compounds such as fulvestrant.
Patent NZ-526835-A (NZ)
Title: Compositions and methods for the release of nucleic acid molecules from solid matrices with alkanol amines
Inventor: XIA JIU-LIN
IPC: C12Q1/6806
Filed: 2001-12-12
Abstract: Disclosed are compositions and methods for releasing nucleic acid molecules from solid matrices. The disclosure further relates to compositions and methods for purifying and isolating nucleic acid molecules from biological materials such as animal tissues and plant matter. The methods of the disclosure can be readily adapted for rapid processing of multiple samples. Thus, the disclosure further provides automated methods for the purification of nucleic acid molecules from numerous samples. The disclosure also relates to kits for removing nucleic acid molecules from solid matrices. The methods relate to the use of a releasing reagent comprising one or more alkanoyl amines such as an ethanolamine. The solid matrix may be a cellulose based matrix or micromesh synthetic plastic matrix, and may comprise a week base, a chelating agent and an anionic surfactant or an anionic detergent and may further comprise uric acid or a urate salt.
Patent NZ-528919-A (NZ)
Title: Amplification process using pyrophosphate
Inventor: CLARK DUNCAN ROY
IPC: C12Q1/6848
Filed: 2002-04-22
Abstract: A method for conducting a nucleic acid amplification reaction, said method comprising forming an amplification reaction mixture in the presence of sufficient of a pyrophosphate salt to prevent primer extension taking place, digesting said pyrophosphate salt with a pyrophosphatase enzyme (PPase), and subjecting said reaction mixture to conditions such that an amplification reaction may proceed. This can be used as a "hot start" amplification. Particular novel pyrophosphatase enzymes for use in the method are also described and claimed.
Patent NZ-530196-A (NZ)
Title: Bouillon powder in which oil content is maximised and the fat content decreased
Inventor: PALZER STEFAN
IPC: A23L23/10
Filed: 2002-05-27
Abstract: A bouillon and/or seasoning powder comprises mainly or only oil and little or no fat. The oil is a healthy oil selected from sunflower oil, mais oil, oil olive and/or canola oil.
Patent NZ-530864-A (NZ)
Title: Protein-containing foodstuff comprising a cross-linking enzyme and a hydrocolloid
Inventor: DEGN PEDER EDVARD
IPC: A23L29/269
Filed: 2002-07-15
Abstract: A composition comprising a hydrocolloid, a protein and an enzyme, wherein the enzyme is a cross-linking enzyme and the dosage of the enzyme is no greater than 20 U/g of protein and the concentration of hydrocolloid is less than 1%, and the protein is soy protein or whey protein.
Patent NZ-535019-A (NZ)
Title: Aerosol formulations for pulmonary administration of medicaments to produce a systemic effect
Inventor: DAVIES REBECCA JAINE
IPC: A61P25/04
Filed: 2003-02-26
Abstract: Disclosed is an aerosol pharmaceutical formulation suitable for use in a pressurised metered dose inhaler for systemic delivery of a non-pulmonary medicament, the formulation comprising the medicament completely dissolved in a solution of an hydrofluoroalkane (HFA) propellant, ethanol in a amount comprised between 2% and 30% w/w and optionally one or more co-solvents with a higher polarity than ethanol in an amount of 0.2% to 10% w/w, wherein the aerosol liquid droplets delivered on actuation of the inhaler have a particle size comprised between 0.5 um and 2.5 um, with a mass median aerodynamic diameter of more than 1 um but less than 2 um and wherein the fine particle fraction is of at least 30%.
Patent NZ-538205-A (NZ)
Title: Air flow control apparatus
Inventor: SAMPSON WILLIAM DARCY
IPC: F16K37/00
Filed: 2003-09-30
Abstract: An apparatus for regulating airflow into a rim mounted vehicle tyre is disclosed. The apparatus has an elongated valve housing (1) with an inlet end (IA), an outlet end (2) and a central portion between the outlet end and inlet end. The outlet end includes a rim insertion portion (3) configured to fit into an aperture in the tyre rim. A piston (8) is disposed within the housing. The piston includes a valve member (19). A coil spring (22) acts between the housing and piston. In use, the piston is biased to an open position for passage of air into the tyre and is movable against the spring bias under air pressure build up in the tyre to a closed position. At the closed position, the valve member seals against a valve seat (21). The piston and spring are located in the central portion of the housing clear of the rim insertion portion. The rim insertion portion is of a reduced size not obstructive to the mounting of the tyre. A band (18) is fitted to the piston and acts as a visual indicator to show the position thereof. The band is visible through a transparent portion of a cap (7) fitted to the housing. The cap can be turned down onto a threaded seat to an over-ride position whereby the band and piston are held to the open position irrespective of tyre pressure.
Patent NZ-538681-A (NZ)
Title: A pharmaceutical composition comprising active biological ingredient carried by particles that form a stable suspension in a liquid indefinitely
Inventor: ROSER BRUCE JOSEPH
Filed: 2000-10-13
Abstract: A pharmaceutical composition is disclosed that comprises an active biological ingredient carried by particles containing a glass that serves to stabilise the active biological ingredient. The particles are suspended in a liquid, with the densities of the liquid and particles being sufficiently similar that the particles form a stable suspension in the liquid indefinitely.
Patent NZ-540698-A (NZ)
Title: Phosphonooxy quinazoline derivatives and their pharmaceutical use
Inventor: HERON NICOLA MURDOCH
IPC: C07D403/14
Filed: 2003-12-22
Abstract: Disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed is the use of the above compound of formula (I) or a pharmaceutically acceptable salt thereof, in the preparation of a medicament for the treatment of colorectal, breast, lung, prostrate, pancreatic or bladder and renal cancer or leukemias or lymphomas.
Patent NZ-546948-A (NZ)
Title: Apparatus for selectively shrinking a film wrapped around a product
Inventor: IRIARTI JOSU ERRASTI
IPC: B65B53/06
Filed: 2004-10-20
Abstract: An apparatus for selectively shrinking a film wrapped around a product is disclosed. The apparatus comprises a frame 9. A driven conveyor 1 is mounted to the frame on which a plurality of products P are transported. A heat source is fixedly disposed underneath the conveyor which generates hot fluid, and a plurality of nozzles 5.1 are fixedly oriented towards the bottom of the conveyor, the hot fluid being conveyed to these nozzles. The apparatus also comprises closing means through which the hot fluid is allowed to pass to the front and rear ends of each product only.
Patent NZ-547196-A (NZ)
Title: Electrically propulsed vehicle steered using differential driving of wheels where the rear wheels always follow in the tracks of the front wheels
Inventor: LUNDSTROM LENNART
IPC: B62D11/00
Filed: 2004-11-12
Abstract: A vehicle (100) with at least three drive axles (A, B, C), whose wheels essentially follow the same wheel tracks is disclosed. Each drive axle (A, B, C) has a pair of drive wheels. The steering system controls the relive rotational speed of the wheels on each side with respect to an overall speed control signal. When the angle between the first set of axles (A, B) is changed, a steering angle sensor modifies the drive signal controlling the relative speed the wheels on each side of those axels. This differential compensating means (20a, 20b) is arranged to register the relative steering angle for each consecutive pair of drive axles, respectively, so that the speed for each of the wheels there after is controlled only by the overall speed of the vehicle and the steering angle for that axle (C) relative to the previous axle (B). The differential compensating means may be achieved with a potentiometer arranged to decreases the speed signal controlling the wheels on the inside of the turn.
Patent NZ-550114-A (NZ)
Title: Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators
Inventor: MJALLI ADNAN M M
IPC: C07D277/56
Filed: 2005-04-20
Abstract: Disclosed is a thiazole compound of formula (Ib), or a pharmaceutically acceptable salt or solvate thereof, wherein A is an amide or amine and where the rest of the substituents are disclosed within the specification. Also disclosed are pharmaceutical compositions comprising the said compound as well as further agents such as hypoglycaemic agents, agents that modulate thermogenesis, lipolysis, gut lotility, fat absorption, satiey and other such second agents.
Patent NZ-550444-A (NZ)
Title: Inhibiting effects of sloughing in wellbores
Inventor: VINEGAR HAROLD J
IPC: H05B6/10
Filed: 2005-04-22
Abstract: Disclosed is a method for treating a subsurface formation, comprising: providing one or more explosives into portions of one or more wellbores selected for the explosion in the formation, the wellbores formed in one or more zones in the formation; controllably exploding the explosives in one or more of the wellbores such that at least some of the formation surrounding the selected wellbores has an increased permeability; and providing one or more heaters in the one or more wellbores; wherein the explosives comprise elongated flexible cords that are configured to be placed in a length of at least one wellbore.
Patent NZ-555883-A (NZ)
Title: Table mount holder for battery powered scissors
Inventor: AGRONIN MICHAEL L
Filed: 2006-07-19
Abstract: A tool holder, particularly for holding battery operated scissors, has a base with a mechanism coupled with the base to secure the base to a surface. A holder is coupled with the base. The holder includes a pair of members pivotal with respect to one another between an opened and closed position to receive and release the scissors. A locking mechanism including a rail on each member and a latch arranged for sliding engagement with the rails locks the pair of members with respect to one another in a closed position.
Patent NZ-564807-A (NZ)
Title: Child seat assemblies
Inventor: MACLIVER KEVIN SCOTT
IPC: B60N2/90
Filed: 2006-06-05
Abstract: A child safety seat assembly (1) for attaching securely and releasably to an existing seat in a vehicle, comprises a seat (1a) with a base portion (3), a back portion (2), one or more straps (7) extending through a slot (4) in the back portion (2), one or more apertures (10') located between the base portion (3) and each slot (4) and at least one bracing member (11). The straps (7) have a primary bracing point located on the assembly. The bracing member (11) cooperates with at least one of the straps (7) and at least one of the apertures (10') to form a secondary bracing point for the strap (7). The bracing member (7) is securable to the seat (1a) from the occupant facing side.
Patent NZ-572050-A (NZ)
Title: Factor VIII conjugated to polyethylene glycol
Inventor: SIEKMANN JUERGEN
IPC: A61K47/48
Filed: 2007-03-29
Abstract: A Factor VIII molecule conjugated to polyethylene glycol (PEG). The Factor VIII molecule comprises; (A) an intact B domain; and (B) at least four PEG molecules bound to the Factor VIII, wherein three of the PEG molecules are bound in the A3 domain and one of the PEG molecules is bound in the B domain. The Factor VIII molecule has at least 80% of the biological activity of native Factor VII when measured and determined by the ratio of the chromogenic activity to antigen value (FVIII:Chr/FVIII:Ag). The in vivo half-life of the Factor VIII molecule is increased by at least 1.5-fold when compared to the native Factor VIII. The PEG molecules can be linear or branched and have a molecular weight from 15,000 Daltons to 150,000 Daltons.
Patent NZ-576021-A (NZ)
Title: Substituted tetrahydropyrrolopyrazine compounds with affinity for the kcnq2/3 k+ channel and the use thereof in medicaments
Inventor: MERLA BEATRIX
IPC: A61K31/4985
Filed: 2007-10-16
Abstract: Disclosed are substituted tetrahydropyrrolopyrazine compounds of formula I, wherein the substituents are as defined in the specification, with affinity for the KCNQ2/3 K+ channel. Also disclosed are processes for their preparation and pharmaceutical compositions comprising said compounds.
Patent NZ-578868-A (NZ)
Title: Pipelaying vessel with plurality of pipe processing stations arranged with at least two modes of operation
Inventor: SCAINI CRISTIAN
IPC: F16L1/00
Filed: 2008-03-06
Abstract: A pipe laying vessel and a method of laying pipeline from the vessel is disclosed. The vessel comprises a deck having at least one pipe processing area. The pipe processing area comprises a plurality of pipe processing stations that are arranged across the width of the vessel. The pipe processing stations are arranged to process pipe sections in parallel with the pipe sections extending longitudinally along the length of the vessel. The pipe processing stations are arranged with at least two modes of operation. In a first mode of operation, the pipe stations are used to form jointed pipe sections (56). Each jointed pipe sections (56) are being formed from a number of single length pipe sections (52, 54) having a length. In a second mode of operation the pipe stations are further used to form jointed pipe sections (58). Each jointed pipe sections (58) are formed from a number of single length pipe sections (50) each having a length. Wherein, Xi>Xj>1 and Li<Lj Where, Xi= the number of single length pipe section used in the first mode of operation; Xj= the number of single length pipe section used in the second mode of operation; Li= the length of single length pipe sections used in the first mode of operation; and Lj= the length of single length pipe sections used in the second mode of operation
Patent NZ-579245-A (NZ)
Title: Beverage ingredient capsule with opening plate having capilliary pressure-relief openings
Inventor: DOGAN NIHAN
IPC: B65D85/804
Filed: 2008-03-20
Abstract: A capsule (1) containing ingredients for producing a beverage, wherein the ingredients are housed in a compartment (3), wherein the capsule (1) comprises a contoured opening plate (5) designed for opening a face of the compartment (3) when the pressure inside the ingredient compartment (3) presses the face against the opening plate (5) of the capsule (1), or an insert and wherein the opening plate (5) or insert is provided with one or several capillary through holes connecting two opposing sides of the opening plate (5) or insert.
Patent NZ-592415-A (NZ)
Title: Process for the preparation of protected l-alanine derivatives
Inventor: FEIBUSH PENINA
IPC: C07C229/12
Filed: 2009-10-27
Abstract: 592415 Disclosed is a process for preparing a compound of formula (I) comprising: reacting a compound of formula (X) with zinc; in the presence of a source of iodine; in a first organic solvent, or a mixture of organic solvents wherein the first organic solvent is nonreactive to the source iodine; to yield the corresponding compound of formula (XI), and reacting the compound of formula (XI) with a compound of formula (XII) in the presence of a palladium catalyst and phosphine ligand system in a second organic solvent or a mixture of organic solvents; to yield the corresponding compound of formula (I). Preferably wherein: the compound of formula (I) is (S)-2-tert-butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethylphenyl)-propionic acid methyl ester; the compound of formula (X) is (R)-2-tert-butoxycarbonylamino-3-iodo-propionic acid methyl ester; the compound of formula (XI) is (R)-2-tert-butoxycarbonylamino-3-(methoxycarbonyl) zinc iodide; the compound of formula (XII) is 4-bromo-3,5-dimethylbenzonitrile; the first and second organic solvent is dimethylacetamide (DMAc); the palladium catalyst and phosphine ligand system is a combination of Pd2(dab)3 and P(o-tol)3; and the compound of formula (X) is reacted with the compound of formula (XII) at a temperature range of from about 50C to about 100C.
Patent NZ-592603-A (NZ)
Title: Aryl gpr120 receptor agonists and uses thereof
Inventor: MA JINGYUAN
IPC: C07D333/16
Filed: 2009-10-20
Abstract: 592603 Disclosed are aryl compounds of Formula (A) or (C) comprising a 5-membered aryl or heteroaryl ring. Specific examples of compounds of Formula (A) or (C) include: 3-(3,5-difluoro-4-((3-isopropyl-1-phenyl-1H-pyrazol-5-yl)methoxy)phenyl)propanoic acid, 2-(3,5-difluoro-4-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)phenyl)cyclopropanecarboxylic acid, 3-(3,5-difluoro-4-((5-methyl-3-phenylisoxazol-4-yl)methoxy)phenyl)-2-methylpropanoic acid, 2-(4-((1-(4-chlorophenyl)-3-methyl-1H-pyrazol-5-yl)methoxy)-3,5-difluorobenzyl)cyclopropanecarboxylic acid, and 3-(7-((1-(4-chlorophenyl)-3-methyl-1H-pyrazol-5-yl)methoxy)-5 2,3-dihydro-1H-inden-4-yl)propanoic acid. Compounds of Formula (A) or (C) are GPR120 agonists which are useful for the treatment of metabolic diseases, including Type I and Type II diabetes and diseases associated with poor glycaemic control.
Patent NZ-593876-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: B01J19/08
Filed: 2010-02-11
Abstract: 593876 Processing biomass Provided is a method of producing a treated biomass comprising: (i) providing a lignocellulosic biomass feedstock; (ii) determining the lignin content of the biomass feedstock; (iii) irradiating the biomass feedstock with ionizing radiation, wherein the amount of ionizing radiation is sufficient to depolymerize the biomass feedstock or produce cellulose chain scission therein, thereby providing a treated biomass having reduced recalcitrance relative to the recalcitrance of the biomass feedstock. Suitable irradiation dosages in relation to the lignin content are also provided.
Patent NZ-596857-A (NZ)
Title: Pea line ex 08250826 deposited under atcc accession number pta-11547
Inventor: PLOUY ALEXIS
IPC: A01H5/08
Filed: 2011-12-02
Abstract: Provided are seed and plants of the pea line designated EX 08250826 deposited under ATCC accession number PTA-11547. The invention thus relates to the plants, seeds and tissue cultures of pea line EX 08250826, and to methods for producing a pea plant produced by crossing a plant of pea line EX 08250826 with itself or with another pea plant, such as a plant of another line. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of a plant of pea line EX 08250826, including the seed, pod, and gametes of such plants.
Patent NZ-602294-A (NZ)
Title: Monoclonal antibodies against c-met
Inventor: SCHUURMAN JANINE
IPC: C07K16/28
Filed: 2011-03-10
Abstract: Discloses a monoclonal antibody which binds human c-Met comprising a VH region comprising CDRs: SYGIS, WISAYNGYTNYAQKLQG; and DLRGTNYFDY and a VL region comprising the CDRs RASQGISNWLA, AASSLLS and QQANSFPIT.
Patent NZ-603245-A (NZ)
Title: Therapeutic applications of activation of human antigen-presenting cells through dectin-1
Inventor: OH SANKON
IPC: A61K39/395
Filed: 2008-02-22
Abstract: Disclosed is the use of an anti-Dectin-1-specific antibody or functional fragment thereof in conjunction with a TLR4 activator, wherein the anti-Dectin-1-specific antibody or functional fragment thereof is capable of activating a Dectin-1-expressing antigen presenting cell in the manufacture of a medicament for treating a disease selected from viral disease, bacterial diseases, fungal diseases, protozoa diseases, parasitic diseases, tumours, autoimmune diseases, allergies or graft rejection; wherein an effectiveness of antigen presentation by the antigen presenting cell is increased by contacting the antigen presenting cell with the anti-Dectin-1-specific antibody or functional fragment thereof, wherein cytokine and chemokine production of the antigen presenting cell is increased by contacting the antigen presenting cell with the TLR4 activator and wherein the antigen presenting cells comprise an isolated dendritic cell, a peripheral blood mononuclear cell, a monocyte, a B cell, a myeloid dendritic cell, or combinations thereof, and wherein the anti-Dectin-1-specific antibody or fragment thereof is a specific for the ectodomain of Dectin-1.
Patent NZ-629979-A (NZ)
Title: Lockout for fastener-driving tool
Inventor: ZHAO HANXIN
IPC: B25F5/00
Filed: 2013-05-07
Abstract: A combustion-powered rivet or nail gun (50) includes a combustion-powered power source (14) having a combustion chamber (18), a reciprocating piston (22) and driver blade (24), and a valve sleeve (36) reciprocable relative to the power source (14) between a rest position and a firing position. The valve sleeve (36) partially defines the combustion chamber (18). A lockout device (60) is in fluid communication with the combustion power source (14) and includes a reciprocating gas piston (66) connected to a latch (80) in operational proximity to the valve sleeve (36). The lockout device (60) is configured such that upon combustion in the combustion chamber (18), gas from the combustion engages the gas piston (66) and moves the latch (80) to an engaged position in which the valve sleeve (36) is prevented from moving to the rest position. Preventing the valve sleeve from moving until it is in the rest position means that the nail gun is not activated prematurely when there is no nail to be driven.
Patent NZ-703239-A (NZ)
Title: Modular construction for electronic tap
Inventor: BIJU DUVAL RÉMI
IPC: E03C1/05
Filed: 2013-05-29
Abstract: The invention relates to a tap device, in particular an electronic tap for a sink, which defines a water circuit between a water intake point and water outlet point, and which comprises a means for opening/closing the water circuit. The device comprises: a base (3), in particular for attachment to a basin; said base, the water circuit between the water intake and water outlet points and the opening/closing device being assembled into a so-called technical base element (1); a shell (2) which forms the outer casing of the tap, and which comprises a water inlet and a water outlet (21), the shell covering the technical element (1) such that the water outlet point is located opposite the water outlet opening and the base is located opposite the water inlet.