baber/WOPTO huggingface dataset:
Patent ES-2135586-T3 (ES)
Inventor: PETERSON ROBERT JAMES
IPC: B05B11/00
Filed: 1994-04-18
Granted: 1999-11-01
Abstract: A liquid dispensing pump (20) for use with consumer product packages is provided with a shipping seal. The housing of the pump device includes an upper housing (24) and a lower housing (26) which are movable relative to each other between open and closed shipping seal positions. The liquid dispensing pump (20) includes a collapsible pump chamber (40), e.g. a bellows. Integral with the bellows (40) is at least one functional element of the shipping seal. The housing includes cooperating actuation elements which prevent actuation of the pump device when the shipping seal is closed. The housing may also include a tamper evident device which prevents actuation of the pump device prior to removal of the tamper evident tab; and may prevent movement of the housing from the closed shipping seal position to the open shipping seal position prior to removal thereof. The bellows (40) may also include an integral valve including a valve member, a valve seat and a valve opening which are all integral components of a wall of the collapsible pump chamber (40), the valve seat facing one side of the wall and the valve member being formed at an angle away from the other side of the wall so that upon pushing the valve member through the valve opening the valve member is biased against the valve seat.
Patent ES-2097054-T3 (ES)
Inventor: SCHUSTER RUDOLF
IPC: B07C3/08
Filed: 1994-07-07
Granted: 1997-03-16
Abstract: PCT No. PCT/DE94/00784 Sec. 371 Date Feb. 15, 1996 Sec. 102(e) Date Feb. 15, 1996 PCT Filed Jul. 7, 1994 PCT Pub. No. WO95/02469 PCT Pub. Date Jan. 26, 1995A sorting installation, in particular for mail, comprises a plurality of conveyed item carriers, circulating on at least one conveying mechanism, for receiving, transporting and controllably delivering the conveyed items. Each conveyed item carrier has a fixedly arranged wall part and a movably arranged wall part. The movably arranged wall part forms in a closed position together with the fixedly arranged wall part a cross-sectionally U-shaped or V-shaped receiving pocket for the conveyed items. The movably arranged wall part forms in a delivery position together with the fixedly arranged wall part a downwardly open delivery slot for the conveyed items.
Patent ES-2147805-T3 (ES)
Title: Dispositivo para la conexion a masa de cables electricos, especialmente a una carroceria de un vehiculo.
Inventor: SCHALLER THOMAS
IPC: H01R4/64
Filed: 1995-04-29
Granted: 2000-10-01
Abstract: EN UN EQUIPO PARA LA CONEXION A MASA DE MULTIPLES CABLES ELECTRICOS SE PROPONE UNA CONEXION A LA VISTA DE FORMA INMEDIATA Y UN DESARROLLO LIBRE DE COLISION DEL CABLE, CON UN CARRIL BASICO ENCABEZADO EN FORMA DE ETAPA, UTILIZADO A BASE DE MATERIAL CONDUCTOR ELECTRICO, QUE PORTA PERNOS ROSCADOS Y UNA UNION A MASA CONJUNTA PARA LOS PERNOS INDICADOS. LOS PERNOS ROSCADOS VECINOS SE ENCUENTRAN RESPECTIVAMENTE EN DOS ESCALONES DE SUPERFICIE DE APARICION QUE SE ENCUENTRAN A ALTURA DIFERENTE UNO CON RESPECTO A OTRO, QUE EN CASO DE UTILIZACION SIRVEN COMO SUPERFICIES DE COLOCACION PARA EL CONTACTADO DE LAS ZAPATAS DE CABLE EQUIPADAS CON EL CABLE. LA SUPERFICIES DE CONTACTO DE ESCALON DE CARRIL BASICO FORMAN RESPECTIVAMENTE UN TOPE PARA LA LIMITACION DE GIRO DE LA ZAPATA DE CABLE ENCHUFADA SOBRE SU PERNO ROSCADO.
Patent ES-2121268-T3 (ES)
Inventor: PARK YOUNGSOUL
IPC: A43B13/18
Filed: 1995-07-31
Granted: 1998-11-16
Abstract: An outsole of a shoe including a plurality of throughout holes (2) formed at its heel portion (A), its middle portion (B) and its toe portion (C), thereby achieving lightness of the shoe and improvement in cushion effect. A pressing protrusion (4) which is formed at the middle portion (B) of the outsole by the throughout hole (6) provided at the middle portion (B) of the outsole contacts frictionally the concave portion of the wearer's foot, thereby providing the foot-pressing effect for health. The throughout hole (6) provided at the middle portion (B) of the outsole generates an effect of softly massaging the concave portion of the wearer's foot being pressed by the pressing protrusion (4), by virtue of its air cushion. An inclined surface (3) which is provided at the upper surface of the toe portion (C) of the outsole serves to prevent the feet of the wearer from outwardly diverging in the inverted-V form during walking. <MATH>
Patent ES-2134989-T3 (ES)
Title: Procedimiento de limpieza y desinfeccion de articulos textiles y agente de limpieza y desinfeccion biologica.
Inventor: VEITH HORST K
IPC: C11D3/48
Filed: 1995-12-05
Granted: 1999-10-16
Abstract: LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LIMPIEZA Y DESINFECCION DE OBJETOS TEXTILES CONFIGURADOS ESENCIALMENTE DE FORMA PARALELEPIPEDICA, TALES COMO POR EJEMPLO COLCHONES U OTROS OBJETOS ELASTICOS, RELLENOS CON MATERIAL TEXTIL, ASI COMO UN MEDIO DE LIMPIEZA Y DESINFECCION BIOLOGICA, QUE SE COMPONE DE UN PRODUCTO DE CONDENSACION DEL ISOPRENO Y UN ALCOHOL ACTIVO ANTIBACTERIAL, FACILMENTE VOLATIL, CON UN RESTO DE HIDROCARBURO MONOVALENTE. EL CONTENIDO EN ALCOHOL SE ENCUENTRA ENTRE EL 80% Y EL 98%, SIENDO EL RESTO PRODUCTO DE CONDENSACION DEL ISOPRENO, DE MODO QUE EL PRODUCTO DE CONDENSACION DEL ISOPRENO CONTIENE EVENTUALMENTE UN EMULSIFICADOR.
Patent ES-2132510-T3 (ES)
Inventor: COLAIANNA PASQUA
IPC: C08F214/26
Filed: 1995-12-29
Granted: 1999-08-16
Abstract: Tetrafluoroethylene (TFE) thermoprocessable copolymers comprising:       (A) from 0.1 to 15% by moles of a fluorodioxol of formula: <CHEM> wherein RF is a perfluoroalkyl having from 1 to 5 carbon atoms; X1 and X2, equal to or different from each other, are -F or -CF3; Z is selected from -F, -H, -Cl. (B) from 0 to 12% by moles of a perfluorinated monomer selected from hexafluoropropene (HFP) and perfluoropropylvinylether (PPVE), or their mixtures;   (C) TFE forming the remaining part to 100%; with the proviso that the total amount of the monomers (A) and (B) is lower than or equal to 20% by moles.
Patent ES-2131267-T3 (ES)
Inventor: PASUT CLAUDIO
IPC: F16K31/08
Filed: 1995-12-07
Granted: 1999-07-16
Abstract: A solenoid valve for an irrigation control unit comprises a cut-off element (7) movable inside a respective seat (25, 26) between a closed position and an open position; the cut-off element (7) defines inside the seat (25, 26) a chamber (26) in constant communication with the inlet (2) of the solenoid valve, so that the pressure exerted on the cut-off element (7) by the water present at the inlet of the solenoid valve is balanced by the pressure exerted on the cut-off element (7) by the water present in the chamber (26), the cut-off element (7) is provided with a passing conduit (12) that can be opened so that the chamber (26) can be put in communication with the outlet (3) of the solenoid valve so that, since the pressure exerted on the cut-off element (7) by the water present at the inlet of the solenoid valve is no longer balanced by the pressure exerted on the cut-off element (7) by the water present in the chamber (26), the cut-off element (7) is displaced by the thrust of the water present at the inlet of the solenoid valve in said open position; the solenoid valve also comprises a bistable electromagnetic device (14-22) comprising an electromagnetically-operated valve suitable for determining alternatively the closing and the opening of said passing conduit (12) as a result of the generation of an electrical control impulse and up to the generation of an opposite electrical impulse. <IMAGE>
Patent ES-2105863-T3 (ES)
Title: Elevador de lunas electrico con dispositivo de seguridad.
Inventor: PIANI GIORGIO
IPC: E05F15/00
Filed: 1995-03-28
Granted: 1997-10-16
Abstract: UNA VENTANA ELECTRICA DE UN VEHICULO A MOTOR ESTA PROVISTA CON UN DISPOSITIVO DE SEGURIDAD QUE COMPRENDE UN ELEMENTO DE SOPORTE (9) CONECTADO A LA BASE DEL CRISTAL DE VENTANA (5) DE LA VENTANA Y UN ELEMENTO AUXILIAR (14) QUE ES ACCIONADO POR EL MECANISMO DE ACCIONAMIENTO (10, 11) DE LA VENTANA ELECTRICA, Y TRANSFIERE SU MOVIMIENTO AL ELEMENTO DE SOPORTE (9) A TRAVES DE UN MEDIO DE MUELLE (18). EN CASO DE ELEVACION DEL CRISTAL DE VENTANA (5) SE OPONE, HAY UN MOVIMIENTO RELATIVO DEL ELEMENTO AUXILIAR (14) RESPECTO DEL ELEMENTO DE SOPORTE (9) QUE CAUSA LA COMPRESION DE DICHO MEDIO DE MUELLE (18) Y LA ACTIVACION DE MEDIOS DETECTORES (19, 20) QUE PROPORCIONAN LA DETENCION Y/O LA INVERSION DE LA ROTACION DEL MOTOR ELECTRICO IMPULSOR (10).
Patent ES-2120160-T3 (ES)
Title: Cilindro maestro hidraulico.
Inventor: WILLIAMSON MICHAEL
IPC: F16J15/32
Filed: 1994-11-07
Granted: 1998-10-16
Abstract: UN CILINDRO HIDRAULICO PRINCIPAL QUE TIENE UN CUERPO DEL CILINDRO (1) CON UN PISTON (3) QUE SE PUEDE DESLIZAR DENTRO DE EL Y QUE LLEVA UN ELEMENTO DE ESTANQUEIDAD (20) PARA PERMITIR LA PRESURIZACION DE UNA CAMARA DE PRESION (6) Y LA RECUPERACION DEL FLUIDO A TRAVES DE UN ORIFICIO DE RECUPERACION (17) AL RETRAERSE EL PISTON. EL ELEMENTO DE ESTANQUEIDAD (20) ES UN CONJUNTO QUE TIENE UNA PRIMERA JUNTA DE ESTANQUEIDAD (23) DE UN MATERIAL RELATIVAMENTE DURO QUE SE PUEDE DESLIZAR CONTRA LA PARED INTERNA DEL CILINDRO Y UNA SEGUNDA JUNTA DE ESTANQUEIDAD RELATIVAMENTE ELASTICA (25) DISPUESTA PARA QUE ACTUE ENTRE LAS SUPERFICIES DE ESTANQUEIDAD DEL PISTON Y LA PRIMERA JUNTA DE ESTANQUEIDAD PARA ESTABLECER UNA ESTANQUEIDAD A PRUEBA DE LA PRESION DEL FLUIDO DURANTE LA PRESURIZACION DE LA CAMARA (6).
Patent ES-2117408-T3 (ES)
Inventor: VESTESEN SOREN QVIST
IPC: F03D9/22
Filed: 1995-02-16
Granted: 1998-08-01
Abstract: PCT No. PCT/DK95/00066 Sec. 371 Date Aug. 19, 1996 Sec. 102(e) Date Aug. 19, 1996 PCT Filed Feb. 16, 1995 PCT Pub. No. WO95/22692 PCT Pub. Date Aug. 24, 1995A method and a plant for combined production of electricity and fresh water in a stand-alone plant of the wind/diesel type. The method enables the simultaneous production of electricity and fresh water with optimal use of the various units of the plant under all conditions of operation by optimally utilizing the wind energy and minimizing fuel consumption. A continuously operating diesel engine controls the line frequency and the power supply without any energy being accumulated. A preferred embodiment of the plant includes a first closed fluid circuit and a second open fluid circuit, the first closed circuit including at least an electric heating unit receiving energy from a wind turbine, an internal-combustion engine, preferably a diesel engine, and a distillation unit. The distillation unit constitutes a unit common to the first closed and the second open circuits.
Patent ES-2179875-T3 (ES)
Title: Portaherramientas con una abrazadera para insertos con apertura.
Inventor: TJERNSTROM ERIC
IPC: B23B27/16
Filed: 1995-05-24
Granted: 2003-02-01
Abstract: LA INVENCION ESTA RELACIONADA CON UN PORTA HERRAMIENTAS PARA AGARRAR UN ELEMENTO INSERTADO CORTANTE CON ABERTURAS (11) EN UNA CAJA DE UN PORTA HERRAMIENTAS (10). EL MECANISMO ORIGINAL CONSISTE EN LA UTILIZACION DE UNA PRENSA DE SUJECION (18) CUYA PORCION DEL EXTREMO DELANTERO (21) ENTRA EN CONTACTO CON LA PARED DEL AGUJERO DEL AGUJERO CENTRAL DE ELEMENTO INSERTADO (14) EN UN PUNTO (22) SITUADO LEJOS DE LA SUPERFICIE SUPERIOR DEL ELEMENTO INSERTADO (12) MIENTRAS LA SUPERFICIE DE ABAJO (30) DE LA PLANCHA DE SUJECION ENTRA EN CONTACTO CON UNA PORCION DE LA SUPERFICIE SUPERIOR DEL ELEMENTO INSERTADO (12) SITUADA ENTRE DICHO AGUJERO CENTRAL (14) Y UNA SUPERFICIE DE APOYO LATERAL DE PIE TRASERA (17) EN DICHA CAJA QUE RECIBE EL ELEMENTO INSERTADO.
Patent ES-2155893-T3 (ES)
Title: Procedimiento de preparacion de compuestos dopaminergicos tetraciclicos quirales.
Inventor: EHRLICH PAUL P
IPC: C07D491/048
Filed: 1995-08-03
Granted: 2001-06-01
Abstract: UN PROCEDIMIENTO PARA PREPARAR UN COMPUESTO TETRACICLICO QUIRAL DE FORMULA (I), EN DONDE R ES HIDROGENO O UN GRUPO ALQUILO C{SUB,1}-C{SUB,6} Y Z ES OXIGENO, AZUFRE O -CH=CH-, LOS COMPUESTOS TENIENDO USOS COMO AGONISTAS DE DOPAMINA. EL PROCEDIMIENTO ABARCA LA REACCION DE UN MATERIAL DE INICIO QUIRAL E INTERMEDIARIOS QUIRALES SUBSECUENTES EN UNA SERIE DE REACCIONES SINTETICAS DE PRESERVACION DE QUIRALIDAD.
Patent ES-2161922-T3 (ES)
Inventor: GREENBERG RICHARD
IPC: G11B5/55
Filed: 1995-12-06
Granted: 2001-12-16
Abstract: A servo address is encoded in a disk drive system having at least one disk for storing data. A servo address associated with a sector in a track, or cylinder, on a surface of a disk and comprised of a sector number, a track number, and in multiple disk systems, a head number is encoded into the encoded servo address. Encoding the servo address saves disk storage space because the encoded servo address uses fewer bits than a conventional servo address while still enabling the disk drive system to locate positions on the disk.
Patent ES-2118654-T3 (ES)
Inventor: ALT ALBERT
IPC: E05B15/00
Filed: 1996-04-10
Granted: 1998-09-16
Abstract: The component (3) is mounted on the fixed or leaf frame (1,2) of a door or window, and works via a contact face between the frames on relative movement between the latter against a mating component (5) on the other frame. One or the other of the components is on a plug portion (6) inserted in a connection area (8) of a universal holder (7) on one of the frames. The holder can have different connection areas to suit different components, and the plug portion and holder can be secured together by clips or screws. The component (3) can form a vertical guide with horizontal ramp face (4) between the frames for a mating boss (5), the plug portion being inserted vertically from the top. The connection areas are in pairs and symmetrical in the horizontal direction.
Patent ES-2134539-T3 (ES)
Inventor: LOTTNER GUNTER
IPC: G01R11/04
Filed: 1996-06-27
Granted: 1999-10-01
Abstract: The clamp block has at least one clamp arrangement (4), which has a current clamp (7,8) for connecting the meter to a lead of a phase of an electric supply network and for connecting a current path (2) of a measuring mechanism of the meter. The arrangement also has a voltage clamp (9) for connecting a voltage path of the measuring mechanism. The voltage clamp is connected to the current clamp via a releasable contact bridge. The contact bridge is accessible from the front side of the clamp block. The releasable contact bridge has at least one contact element formed as a spring. The free end of the spring preferably lies against a contact surface provided on a further contact element. One of the two contact elements is preferably connected to the current clamp while the other is connected to the voltage clamp.
Patent ES-2167501-T3 (ES)
Inventor: MENOVCIK GREGORY C
IPC: C09D201/00
Filed: 1996-09-28
Granted: 2002-05-16
Abstract: A curable coating composition is described comprising   (A) a compound comprising carbamate or urea and hydroxyl functional groups that is the reaction product of   (1) a compound comprising a carbamate or urea group or a group that can be converted to a carbamate or urea group, and an active hydrogen group that is reactive with a lactone or a hydroxy carboxylic acid, and   (2) a lactone or a hydroxy carboxylic acid,   (B) a compound comprising at least one group that is reactive with carbamate and at least one group that is reactive with hydroxyl, or a plurality of groups that are reactive with both carbamate and hydroxyl.
Patent ES-2163584-T3 (ES)
Inventor: WINKELMAN HEINRICH
IPC: B29C53/60
Filed: 1996-02-09
Granted: 2002-02-01
Abstract: A hydropneumatic filament-wound pressure vessel is disclosed. The vessel has first and second cup-shaped tank liners having circular open mouths which are provided with a seal and diaphragm assembly. The seal assembly includes a pocket formed by an inner wall and shelf associated with the first liner and a ledge associated with the second liner. The shelf, ledge and cylindrical wall cooperate with an inner surface of the second liner to provide an O-ring pocket. An O-ring is provided in the pocket and the O-ring defines the periphery of a flexible diaphragm which divides the interior of the liners into separate pressure chambers. A continuous filament is wound over the surface of the liners in an isotensoid pattern. Each liner has a geodesic dome surface extending between a diameter of the liner and a polar opening. The dome surface is defined by oppositely curving surfaces of revolution of a meridia joined by an inflection point. The first surface of revolution curves from the liner diameter to a first point just unto but not at said inflection point. The second surface of revolution curves from the polar opening to a second point just unto but not at said inflection point in a direction opposite the curvature of the first surface of revolution. The first and second surfaces are joined, and the inflection point is traversed by a straight line third surface of revolution closely approximating geodesic curvature through the inflection point. <IMAGE>
Patent ES-2179161-T3 (ES)
Title: Conjunto de control del cambio del divisor automatico y manual.
Inventor: LANTING MARK LORING
IPC: F16H61/70
Filed: 1996-04-24
Granted: 2003-01-16
Abstract: UN ENSAMBLAJE DE VALVULA DE CONTROL (94) PARA PERMITIR EL DESPLAZAMIENTO DIVISOR MANUAL Y AUTOMATICO EN UN SISTEMA DE TRANSMISION DE UN VEHICULO DEL TIPO DIVISOR DE COMPUESTO (92). EL ENSAMBLAJE DE CONTROL ESTA INTERPUESTO EN SERIES ENTRE UN CONDUCTO SELECTIVAMENTE PRESURIZADO Y AGOTADO (108) CONTROLADO MEDIANTE UNA VALVULA SELECTORA MANUAL (104) Y UN CONDUCTO PILOTO (110) QUE CONTROLA LA OPERACION DE UN ACTUADOR DE DESPLAZAMIENTO DIVISOR (86). EL ENSAMBLAJE ESTA DISEÑADO PARA FALLAR EN UNA POSICION QUE PERMITE LA COMUNICACION DE FLUIDO ENTRE EL CONDUCTO SELECTIVAMENTE PRESURIZADO Y AGOTADO Y EL CONDUCTO PILOTO.
Patent ES-2151129-T3 (ES)
Title: Recinto para alojar un empalme de cables electricos.
Inventor: RODRIGUES JULIO F
IPC: H02G15/10
Filed: 1996-04-26
Granted: 2000-12-16
Abstract: SE PRESENTA UN CERRAMIENTO PARA UN EMPALME ELECTRICO (20) PARA CERRAR UN EMPALME DE UN CABLE ELECTRICO QUE INCLUYE UN ALOJAMIENTO DE CERRAMIENTO (22). EL CERRAMIENTO ESTA FORMADO DE UNA PARTE DE ALOJAMIENTO INFERIOR (24) Y UNA PARTE DE TAPA (26) QUE DEFINEN UN INTERIOR ENTRE AMBAS. LA PARTE DEL ALOJAMIENTO INFERIOR INCLUYE UNA SUPERFICIE DE FONDO (42), UNA PARED QUE SE EXTIENDE HACIA ARRIBA QUE UNE LA SUPERFICIE DEL FONDO Y UNA SUPERFICIE SUPERIOR ABIERTA OPUESTA A LA SUPERFICIE DEL FONDO. LA PARTE DEL ALOJAMIENTO INFERIOR INCLUYE ADEMAS UNA ABERTURA PARA LA ENTRADA DEL CABLE (54) A TRAVES DE LA PARED PARA PERMITIR LA ENTRADA DEL CABLE EN EL INTERIOR DE LA PARTE DEL ALOJAMIENTO INFERIOR. LA PARTE DE LA TAPA (26) ES POSICIONABLE SOBRE LA SUPERFICIE SUPERIOR ABIERTA SOBRE LA PARTE DEL ALOJAMIENTO INFERIOR DE MANERA QUE ENCIERRE EL EMPALME DEL CABLE DENTRO DEL ALOJAMIENTO. LA PARTE DE LA TAPA Y LA PARED INCLUYEN CADA UNA, UNA ABERTURA PARA RELLENO ENCAPSULANTE PARA PERMITIR QUE EL INTERIOR DELALOJAMIENTO SEA RELLENADO POR GRAVEDAD CON UN ENCAPSULANTE POLIMERIZABLE, ESTANDO EL ALOJAMIENTO POSICIONADO EN MULTIPLES POSICIONES DIFERENTES.
Patent ES-2161991-T3 (ES)
Inventor: HELAINE CHRISTIAN
IPC: A01J25/15
Filed: 1996-05-13
Granted: 2001-12-16
Abstract: The method for eliminating by pressing the whey contained in curd (3) located in a micro-perforated cheese mould (2) consists of placing the cheese mould in a sealed enclosure (1). Two pressing cycles are made, each comprising a first phase in which a pressure is exerted on the curd contained in the mould, and a depression created in the enclosure. In the second phase the pressure exerted on the curd is ended and a pressure created in the enclosure equal to atmospheric pressure. Each pressing cycle has a duration of about 30 minutes and can be repeated up to ten times according to the nature of the whey. During the second phase the high pressure in the enclosure is less than or equal to 10<4> Pa during the second phase
Patent ES-2120274-T3 (ES)
Title: Utilizacion de un extracto de una bacteria filamentosa no fotosintetica y composicion.
Inventor: BRETON LIONEL
IPC: A61K35/74
Filed: 1996-08-13
Granted: 1998-10-16
Abstract: LA PRESENTE INVENCION SE REFIERE A LA UTILIZACION DE AL MENOS UN EXTRACTO DE AL MENOS UNA BACTERIA FILAMENTOSA NO FOTOSINTETICA COMO ANTAGONISTA DE SUSTANCIA P, EN UNA COMPOSICION COSMETICA O PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA. LA INVENCION SE REFIERE TAMBIEN A LA UTILIZACION DE AL MENOS UN EXTRACTO DE AL MENOS UNA BACTERIA FILAMENTOSA NO FOTOSINTETICA EN UNA COMPOSICION COSMETICA O PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA DESTINADA A TRATAR LOS TRASTORNOS ASOCIADOS A UN EXCESO DE SINTESIS Y/O DE LIBERACION DE SUSTANCIA P. LA INVENCION SE REFIERE ADEMAS A DIVERSAS COMPOSICIONES QUE CONTIENEN UN EXTRACTO DE AL MENOS UNA BACTERIA FILAMENTOSA NO FOTOSINTETICA Y UN PROCEDIMIENTO DE TRATAMIENTO COSMETICO.
Patent ES-2176425-T3 (ES)
Title: Manija ergonomica.
Inventor: CASTELLINI FRANCO
IPC: A61G15/16
Filed: 1996-03-26
Granted: 2002-12-01
Abstract: UN MANGO (5) CONSTA DE UN PRIMER BRAZO (6) SUJETO A UNA TABLETA (1) PARA SUJETAR LAS PIEZAS MANUALES (2), EL EXTREMO LIBRE, SUPERIOR DEL BRAZO ESTA EQUIPADO CON UN SEGUNDO BRAZO (7) QUE SE EXTIENDE EN PARALELO CON UNA LINEA (L) DEFINIDA POR LA FILA DE SELECTORES (4) SITUADOS SOBRE UNA CONSOLA (3) SOBRE LA TABLETA (1) A LO LAGO DE UNA LONGITUD (L2) PROPORCIONAL A LA LONGITUD (L1) DE LA LINEA (L).
Patent ES-2242965-T3 (ES)
Inventor: MCGUIGAN CHRISTOPHER
IPC: A61K31/7076
Filed: 1996-03-13
Granted: 2005-11-16
Abstract: Aryl substituted phosphoryl derivatives of the formula In which Ar is phenyl, naphthyl, or pyridyl, Y is O or S, X<SUP>1 </SUP>is O, NR<SUP>3</SUP>, S, CR<SUP>3</SUP>R<SUP>4</SUP>, CR<SUP>3</SUP>W<SUP>1 </SUP>or CW<SUP>1</SUP>W<SUP>2</SUP>, X<SUP>2 </SUP>and X<SUP>6 </SUP>are a bond or X<SUP>6 </SUP>is CH<SUB>2 </SUB>and X<SUP>2 </SUP>is O, NR<SUP>3</SUP>, S, CR<SUP>3</SUP>R<SUP>4</SUP>, CR<SUP>3</SUP>W<SUP>1 </SUP>or CW<SUP>1</SUP>W<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are H, alkyl or phenyl, groups, W<SUP>1 </SUP>and W<SUP>2 </SUP>are heteroatoms, X<SUP>3 </SUP>is alkylene, X<SUP>4 </SUP>is oxygen or CH<SUB>2</SUB>, X<SUP>5 </SUP>is a bond or CH<SUB>2</SUB>, Z is O, NR<SUP>5</SUP>, S, alkyl or phenyl, R<SUP>5 </SUP>is H, alkyl or phenyl, J is H, alkyl, phenyl, or a heterocyclic or polycyclic group, Q is O, NR<SUP>6</SUP>, S, CR<SUP>6</SUP>R<SUP>7</SUP>, CR<SUP>6</SUP>W<SUP>3 </SUP>or CW<SUP>3</SUP>W<SUP>4</SUP>, R<SUP>6 </SUP>and R<SUP>7 </SUP>are H, alkyl or phenyl, and W<SUP>3 </SUP>and W<SUP>4 </SUP>are hetero atoms, T<SUP>1 </SUP>and T<SUP>2 </SUP>are H or CH<SUB>2</SUB>R<SUP>8</SUP>, R<SUP>8 </SUP>is H, OH or F, or T<SUP>1 </SUP>and T<SUP>2 </SUP>together are -CH-CH- or -C(R<SUP>9</SUP>)(R<SUP>10</SUP>)C(R<SUP>11</SUP>)(R<SUP>12</SUP>)-, R<SUP>9 </SUP>is H, halogeno, CN, NH<SUB>2</SUB>, CO-alkyl, or alkyl, R<SUP>10</SUP>, R<SUP>11</SUP>, and R<SUP>12 </SUP>are H, N<SUB>3</SUB>, halogen, CN, NH<SUB>2</SUB>, CO-alkyl, or alkyl, and B is a purine or pyrimidine base, have antiviral activity, as for example against HIV. Particularly preferred are thymine and adenine derivatives of amino acid phenoxyphosphoroamidates. A typical embodiment is 2',3'-dideoxy-2',3'-didehydrothymidine 5'-(phenyl methoxy alaninyl) phosphoroamidate which can be prepared from phenyl methoxy alaninyl phosphorochloridate and 2',3'-dideoxy-2',3'-didehydrothymidine.