baber/WOPTO huggingface dataset:
Patent AU-2016202243-A1 (AU)
Title: Assays
Inventor: ERMANTRAUT EUGEN
IPC: C12Q1/68
Filed: 2016-04-11
Abstract: Abstract A method, comprising (a) providing an amount of a reporter compound; a first binding member being configured to bind an anchor group of a capture molecule; a second binding member capable of capturing the reporter compound; an amount of a 5 target nucleic acid capable of forming complexes with the reporter compound, the forming of complexes with the reporter compound inhibiting capturing of the reporter compound by the second binding member; and an amount of capture molecules wherein each capture molecule comprises a binding portion specific to a region of the target nucleic acid and an anchor group; (b) forming complexes each 10 comprising a target nucleic acid and a capture molecule; (c) contacting the complexes with the first binding member to bind at least a subset of the complexes to the first binding member; (d) releasing at least a subset of the amount of target nucleic acid from the first binding member; (e) forming complexes of a subset of the amount of reporter compound with at least a subset of the amount of target nucleic 15 acid; (f) capturing a remaining subset of the amount of reporter compound not in complex with a target nucleic acid on the second binding member; and (g) determining a value indicative of the presence and/or amount of reporter compound captured on the second binding member.
Patent AU-2016216605-A1 (AU)
Title: Liquid-augmented, generated-gas fire suppression systems and related methods
Inventor: SAMPSON WILLIAM P
IPC: A62C13/22
Filed: 2016-08-17
Abstract: Fire suppression apparatuses include a housing with gas generant material disposed therein, an initiator for igniting the gas generate material, and a cooling system. The cooling system includes a first chamber with a coolant material disposed therein and a second chamber. The coolant material is caused to flow from the first chamber into the second chamber to cool gas formed by the ignition of the gas generant material upon exiting from the housing under pressure. The cooling system may further include a piston disposed within the first chamber and movable responsive to gas pressure. Methods for cooling a fire suppressant gas and methods for suppressing a fire include flowing a fire suppressant gas into first and second chambers of a cooling system, flowing a coolant material from the first chamber into the second chamber, and contacting the fire suppressant gas with the coolant material to cool the fire suppressant gas.
Patent AU-2016222389-A1 (AU)
Title: Lightweight low-cost solar concentrator
Inventor: HAHN HARRY KURT
IPC: F24S23/74
Filed: 2016-08-31
Abstract: Abstract: Disclosed is a Lightweight low-cost solar concentrator comprising two sheets which are connected or sealed to each other on their outer periphery to define a gasproof chamber which is inflated with air or gas (5) in order to form the inflated mirror. One sheet is transparent (1) for sunlight (3) and the other sheet has a reflecting mirror-like surface (2). The periphery of the two connected sheets is fixed to a rigid support or envelopes it. The rigid support, such as a support frame (6), which is further fixed to a mirror support structure (7), defines the outline of the inflatable mirror and provides stability. For a defined adjustment of the pressure in the air or gas (5) which is enclosed in the gasproof chamber means for inflating or deflating the mirror (4) and a device for the generation of a defined pressure in the air or gas (72) are provided. The device for the generation of a defined pressure is an automatic device which is constantly or occasionally in conjunction with the gasproof chamber in such a way, that a defined overpressure is automatically generated and maintained in the air or gas enclosed in the inflatable mirror, in order to ensure a constant focal distance of the inflatable mirror. The inflatable mirror comprises a receiver (10) for concentrated electromagnetic radiation (8) which is either fixed on a rigid (9) or on an adjustable receiver support structure (11).
Patent AU-2016222998-A1 (AU)
Title: Surgical instrument and method
Inventor: SIMPSON JOSHUA W
IPC: A61B17/70
Filed: 2016-02-22
Abstract: A surgical instrument comprises a first member including a lateral projection having a locking surface that defines an elongated cavity. The locking surface is engageable with a longitudinal member to fix the longitudinal member with the first member. A second member includes at least one mating element being engageable with a spinal construct. The first member is axially translatable relative to the second member in a first direction to tension the longitudinal member and in a second direction to release tension from the longitudinal member. Systems and methods are disclosed.
Patent AU-2016246104-A1 (AU)
Title: Combinations of amisulpride and another anti-emetic for treating nausea and vomiting
Inventor: GILBERT JULIAN CLIVE
IPC: A61P1/08
Filed: 2016-04-11
Abstract: A kit comprises at least one non-IV injectable unit dose of amisulpride and at least one dose of an acute-phase anti-emetic, for simultaneous, separate or sequential use in the treatment or prevention of chemotherapy- or radiotherapy-induced nausea and/or vomiting in a subject, wherein the subject is receiving or has received a chemotherapy or radiotherapy treatment regimen, and wherein the dosage regimen comprises the administration of the or each acute-phase anti-emetic on day 1, day 1 being the same day that a chemotherapy or radiotherapy is administered, and the administration of the, or at least one of the, non-IV injectable unit doses of amisulpride on day 2. Also provided is a kit comprising at least one non-IV injectable unit dose of amisulpride and at least one unit dose of IV amisulpride. Further provided is a non-IV injectable formulation of amisulpride, for use in the treatment or prevention of delayed-phase chemotherapy- or radiotherapy-induced nausea and/or vomiting in a subject.
Patent AU-2016246513-A1 (AU)
Title: Convertible glenoid
Inventor: HOPKINS ANDREW
IPC: A61F2/40
Filed: 2016-04-06
Abstract: A glenoid system (100) includes a baseplate (102) configured to attach to a glenoid cavity of a patient. In a primary configuration, a biocompatible plastic liner (332) can snap into a circumferential groove (120) on the baseplate, to attach to a lateral - facing surface (104) of the baseplate, at one or more locations around the groove. In a reverse configuration, a glenosphere (544, 644) can attach to an adapter (542, 642), which in turn can attach to the lateral - facing surface of the baseplate. The adapter can introduce lateral and/or angular offsets between the baseplate and the glenosphere, which can correct for unwanted offsets or inclinations. A middle peg extension (752) can screw onto a medial end of the middle peg (114), which can offer different combinations of peg length and peg material. The baseplates can be made available in various discrete sizes, each of which has the same distance between the middle peg and an inferior screw hole (112).
Patent AU-2016254729-A1 (AU)
Title: Targeted nanocarriers for targeted drug delivery of gene therapeutics
Inventor: FURCH MARCUS
IPC: A61K9/127
Filed: 2016-04-29
Abstract: The present invention relates to targeted nanocarriers - also termed nanomedicines - and methods of preferentially, or actively, targeting and delivering a tool for gene transfer or genome editing (i.e., a plasmid or a restriction enzyme - such as a zinc finger nuclease, a CRISPR/Cas system, or a TALEN) or a tool for gene silencing or post-transcriptional regulation of gene expression (i.e., a microRNA, a siRNA, a mRNA, an antisense oligonucleotide, or a sense oligonucleotide) to a range of mammalian cell species. Cell- specific targeting is achieved by using nanocarriers featuring suitable targeting anchors having a targeting moiety that can be a carbohydrate, an antibody or an antibody fragment, a non-antibody protein derivative, an aptamer, a lipoprotein or a fragment thereof, a peptidoglycan, a lipopolysaccharide or a fragment thereof, or a CpG DNA. Such targeting anchors may or may not include a polymeric spacer like polyethylene glycol. The nanomedicines shall allow to therapeutically address a range of mammalian disease entities via various application routes. These indications include malignant diseases, autoimmune diseases, inherited disorders, metabolic disorders, or infectious diseases.
Patent AU-2016269758-A1 (AU)
Title: Railway braking system for a railway vehicle
Inventor: THOMAS DIDIER
IPC: B60T13/66
Filed: 2016-06-03
Abstract: The invention relates to a railway braking system (1) comprising a braking device (2) provided with a body (7), a single piston (8) that can move with respect to said body to act on a brake linkage (5), and delimiting, together with said body, a pressure chamber (17) supplied by a pressure medium source (55, 7) for placing said piston in a rest position where said linkage applies no force on a braking member (6) of a railway vehicle, first and second seals (28, 30) housed between a first section (21) of said piston and said body, and third and fourth seals (32, 34) housed between a second section (22) of said piston and said body; said first and third seals being configured to form a primary sealing of said pressure chamber and said second and fourth seals being configured to form a secondary sealing of said pressure chamber.
Patent AU-2016280832-A1 (AU)
Title: Method of treating primary focal segmental glomerulosclerosis
Inventor: LEDBETTER STEVEN R
IPC: A61K39/395
Filed: 2016-06-17
Abstract: A method of treating primary focal segmental glomerulosclerosis in a patient having an APOL1 variant, comprising intravenously administering a TGFβ antagonist to the patient.
Patent AU-2016298826-A1 (AU)
Title: Antibacterial therapeutics and prophylactics
Inventor: SENGUPTA SHILADITYA
IPC: C07D405/14
Filed: 2016-07-28
Abstract: The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more specifically to bacterial infections with antibiotic resistant pathogens.
Patent AU-2016301375-A1 (AU)
Title: Signal amplification in solution-based plasmonic specific-binding partner assays
Inventor: MEHRA RAJESH K
IPC: G01N21/17
Filed: 2016-08-04
Abstract: The present invention relates to analyte detection devices and methods of using such devices to detect minute quantities of a target analyte in a sample. In particular, the invention provides a method of detecting a target analyte in a sample comprising mixing the sample with a first detection conjugate and a second detection conjugate in solution, wherein the first and second detection conjugates comprise metallic nanostructures coupled to binding partners that are capable of specifically binding to the target analyte if present in the sample to form a complex between the first detection conjugate, the analyte, and the second detection conjugate, wherein a change in an optical signal upon complex formation indicates the presence of the target analyte in the sample. Methods of preparing nanostructures and nanoalloys, as well as nanostructures and nanoalloys conjugated to binding partners, are also described.
Patent AU-2016308672-A1 (AU)
Title: A glove for elevated working tool securement
Inventor: SALISBURY RICHARD
IPC: A41D19/015
Filed: 2016-08-18
Abstract: There is provided a glove for elevated working tool securement. The glove comprises an anchor point such that, in use, if a tool tethered to the anchor point is dropped, the anchor point secures the tool to the glove. The glove can further comprise a cuff, such as a user tightenable cuff comprises a band fastening portion, configured such that, in use, if a tool tethered to the anchor point is dropped, the cuff secures the glove tightly to a wrist to withstand the forces exerted on the anchor point.
Patent AU-2016324495-A1 (AU)
Title: Carborane compounds and methods of use thereof
Inventor: TJARKS WERNER
IPC: A61K33/24
Filed: 2016-09-19
Abstract: Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ERβ) agonists. In some examples, the compounds can be selective ERβ agonists. Also provided herein are methods of treating, preventing, or ameliorating cancer in a subject, suppressing tumor growth in a subject, treating an inflammatory disease in a subject, treating a neurodegenerative disease in a subject, treating a psychotropic disorder in a subject, or a combination thereof, by administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof.
Patent AU-2016336270-A1 (AU)
Title: High performance fibres composite sheet
Inventor: MARISSEN ROELOF
IPC: C08J5/04
Filed: 2016-10-07
Abstract: The invention relates to a method for manufacturing a composite sheet comprising high performance polyethylene fibres and a polymeric resin comprising the steps of assembling HPPE fibres to a sheet, applying an aqueous suspension of a polymeric resin to the HPPE fibres, partially drying the aqueous suspension, optionally applying a temperature and/or a pressure treatment to the composite sheet wherein the polymeric resin is a homopolymer or copolymer of ethylene and/or propylene. The invention further relates to composite sheets obtainable by said method and articles comprising the composite sheet such as helmets, radomes or a tarpaulins.
Patent AU-2016348436-A1 (AU)
Title: Systems and methods for fracturing a multiple well pad
Inventor: KAJARIA SAURABH
IPC: E21B43/26
Filed: 2016-11-04
Abstract: A flow system (64) for use at a hydraulic fracturing well site, including a tree (14) attached to a wellhead (16), an inlet head (20) in fluid communication with at least one hydraulic fracturing pump (10) at the well site, and an adjustable fluid conduit (56) providing fluid communication between the inlet head and the tree. The flow system further includes a valve (66) in the fluid conduit and having an open position and a closed position, the valve permitting fluid flow through the fluid conduit when in the open position, and preventing fluid flow through the fluid conduit when in the closed position, at least a portion (56a) of the fluid conduit being positioned between the valve and the tree.
Patent AU-2016369417-A1 (AU)
Title: Three-dimensional polymer networks with channels situated therein
Inventor: KLAPPROTH HOLGER
IPC: C12Q1/68
Filed: 2016-12-16
Abstract: The disclosure provides three-dimensional crosslinked polymer networks comprising one or more channels extending from the surface and/or near the surface of the network into the interior of the network, arrays comprising the networks, processes for making the networks, and uses of the networks and arrays.
Patent AU-2016377689-A1 (AU)
Title: Sweetened dairy products with steviol glycosides and lactase enzyme
Inventor: MCCORMICK CASEY
IPC: A23C9/12
Filed: 2016-12-22
Abstract: The invention concerns a sweetened dairy product comprising a dairy material, at least one steviol glycoside, and a lactase enzyme.
Patent AU-2016389907-A1 (AU)
Title: Latch for sequentially extended mechanical mast
Inventor: WASSON ANDREW PAUL
IPC: H01Q1/10
Filed: 2016-11-22
Abstract: An automatic locking latch system is provided that is driven by the normal extension and retraction of the mast, reduces the inherent rotation and deflection of the mast due to clearances, and operates more smoothly and quietly than conventional locking systems. The locking latch system also fits reasonably within the existing footprint of a typical mechanical mast.
Patent WO-2017214673-A1 (WO)
Title: Souche de levure et ses utilisations
Inventor: ANGELUCCI CONSTANZA
IPC: C12P7/06
Filed: 2017-06-14
Abstract: La présente invention concerne d'une manière générale une nouvelle souche de levure déposée auprès du NMI (National Measurement Institute) sous le numéro d'accès V16/014811, et les cultures correspondantes. La présente invention concerne également d'une manière générale l'utilisation de la souche de levure V16/014811, les cultures correspondantes et les cellules de levure dérivées de ces cultures, pour la fabrication de produits fermentés, notamment des produits alimentaires fermentés et des boissons fermentées.
Patent WO-2018112531-A1 (WO)
Inventor: BRODIE GRAHAM
IPC: A01M21/04
Filed: 2017-12-20
Abstract: L'invention concerne un appareil d'application d'énergie micro-ondes pour irradier un matériau, comprenant : au moins une source d'énergie micro-ondes configurée pour générer de l'énergie micro-ondes ; au moins un applicateur de micro-ondes ayant une face d'émission d'énergie de micro-ondes comprenant un résonateur diélectrique ou un applicateur de micro-ondes à ondes lentes pour diriger une énergie de micro-ondes vers le matériau à irradier ; et un guide d'ondes couplant l'énergie micro-ondes de la source d'énergie micro-ondes à l'applicateur de micro-ondes pour une application sur un matériau à traiter.
Patent AU-2017214603-A1 (AU)
Title: Radio resource allocation in a narrowband communication system
Inventor: SAXENA VIDIT
IPC: H04L5/00
Filed: 2017-02-03
Abstract: Methods and apparatuses of resource allocation for wireless communication are presented. In an example, a user equipment (12) may contain radio circuitry and processing circuitry such that the user equipment (12) is configured to obtain a set of multiple indices, where each index in the set of multiple indices corresponds to a different uplink resource allocation from a set of uplink resource allocations (11) formed from twelve contiguous subcarriers. In an aspect, the set of uplink resource allocations (11) includes an allocation of the twelve contiguous subcarriers, two allocations of six contiguous subcarriers, four allocations of three contiguous subcarriers, and twelve allocations of a single subcarrier. In a further aspect, the user equipment (12) can receive an index indication corresponding to an index from the set of multiple indices from the base station (10). Also, the user equipment (12) can transmit data to the base station (10) using the resource allocation corresponding to the received index indication.
Patent AU-2017222108-A1 (AU)
Title: Method of implantation of cell aggregates and tissue fragments
Inventor: SCHOUENBORG JENS
IPC: A61N1/05
Filed: 2017-02-23
Abstract: In a method for implantation of a physically stabilized aggregate of living cells or tissue fragment is injected into a channel provided in soft tissue filled with an aqueous gel. Also discloses are methods of stabilizing such aggregates and fragments and of forming such channel in soft tissue as well as means for carrying out the methods.
Patent AU-2017227332-A1 (AU)
Title: Composition used to improve symptoms of autism spectrum disorder, and method using same for improving symptoms of autism spectrum disorder
Inventor: MIYATA TOSHIO
IPC: A61K31/44
Filed: 2017-03-02
Abstract: The present invention provides a composition that is effective in improving the symptoms of autism spectrum disorder. The composition is characterized in containing, as an active ingredient, at least one type of pyridoxamine compound selected from the group consisting of pyridoxamine and a pharmaceutically acceptable salt thereof. The composition can also be used in combination with at least one type of thiamine compound selected from the group consisting of thiamine, a derivative thereof, and a pharmaceutically acceptable salt thereof.
Patent AU-2017235361-A1 (AU)
Title: Means and methods for treating HSV
Inventor: STERGIOU GARYFALIA
IPC: A61K39/12
Filed: 2017-03-14
Abstract: The present invention relates to a vaccine composition comprising a multimeric complex of Herpes Simplex Virus (HSV) polypeptides for the treatment or vaccination against HSV. The present invention also relates to a vector comprising a polynucleotide encoding the HSV polypeptides and a host cell comprising the vector. The present invention further comprises a method for producing the vaccine composition.
Patent AU-2017249373-A1 (AU)
Title: Hand-held machine tool comprising a drive motor
Inventor: WALKER NICO
IPC: B25F5/00
Filed: 2017-04-10
Abstract: The invention relates to a hand-held machine tool, in particular a sanding machine, comprising a rod-type handle element (12) for the user to grip and a processing head (11) which is moveably mounted on the handle element (12) by means of a joint assembly (13). The processing head has an electric drive motor (100) for driving a tool holder (19) provided for holding a processing tool (20) and a speed-reducing gearbox (80) between the drive motor (100) and the tool holder (19), said gearbox being designed to achieve a reduction in speed of an output (81) of the drive motor (100) relative to a speed of the tool holder (19). According to the invention, the drive motor (100) is a brushless motor and a power supply system (40) for the drive motor (100) is arranged at a distance from the drive motor (100) on the handle element (12), the power supply system being connected to the drive motor (100) by means of a cable arrangement (41).
Patent AU-2017254525-A1 (AU)
Title: A system and method for network incident identification, congestion detection, analysis, and management
Inventor: ZAFER MURTAZA
IPC: H04L12/24
Filed: 2017-04-18
Abstract: A system and method for automatic detection of a network incident from real-time network data is disclosed. The method includes: collecting real-time network data; executing performance calculations on the real-time network data to compute performance metrics; and detecting a pattern over a time window, wherein detecting a pattern includes detecting a proportion of metric values crossing a threshold exceeding a defined percentage amount, detecting a presence of a sequence of metric values, detecting a time-ordered stretch of metric values with a length of the time-ordered stretch exceeding a defined threshold, detecting a cyclical presence of a sequence of metric values, or combinations thereof.
Patent AU-2017255362-A1 (AU)
Title: Composition, crocins active site, and uses thereof
Inventor: YAO XINSHENG
IPC: A61K31/7024
Filed: 2017-03-16
Abstract: A composition, and a crocins active site extracted from
Patent AU-2017266905-A1 (AU)
Title: Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof
Inventor: GARRETT-THOMSON SARAH C
IPC: C07K16/28
Filed: 2017-05-17
Abstract: The present disclosure provides variant PD-L1 immunomodulatory polypeptides, and fusion polypeptides comprising the variant immunomodulatory peptides. The present disclosure provides T- cell modulatory multimeric polypeptides, and compositions comprising same, where the T-cell modulatory multimeric polypeptides comprise a variant immunomodulatory polypeptide of the present disclosure. The present disclosure provides nucleic acids comprising nucleotide sequences encoding the T-cell modulatory multimeric polypeptides, and host cells comprising the nucleic acids. The present disclosure provides methods of modulating the activity of a T cell; the methods comprise contacting the T cell with a T-cell modulatory multimeric polypeptide of the present disclosure.