baber/WOPTO huggingface dataset:
Patent CA-3086362-A1 (CA)
Title: Novel quinolone compounds as inhibitors of the bcl6 btb domain protein-protein interaction and/or as bcl6 degraders
Inventor: CHAU ANH MY
IPC: A61P35/02
Filed: 2018-12-20
Abstract: The present application relates to compounds of Formula I or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment of diseases, disorders or conditions that are treatable by inhibiting interactions with BCL6 BTB and/or by degrading BCL6, such as cancer.
Patent CA-3087214-A1 (CA)
Title: Peptides having protease activity for use in the treatment or prevention of coronavirus infection
Inventor: GUDMUNDSDOTTIR AGUSTA
IPC: A61P31/14
Filed: 2019-01-07
Abstract: The present invention provides a polypeptide having protease activity for use in the treatment or prevention of coronavirus infection in a mammal. In particular, the invention relates to treatment or prevention of a coronavirus infection in a human, using trypsins.
Patent CA-3088240-A1 (CA)
Inventor: FJELDE OLE GUNNAR
IPC: B23B51/04
Filed: 2018-12-18
Abstract: A core drill (1) arranged to drill in the ground (99), the core drill (1) comprising a sleeve (2) with a first end portion (22) and a bit ring (3) which is detachably attached in a rotationally rigid manner to the first end portion (22), one of the sleeve (2) and the bit ring (3) having a groove (61) with two converging side faces (62), and the other one of the sleeve (2) and the groove (3) having a protrusion (63) with two complementary side faces (64), and the groove (61) and the protrusion (63) being arranged to engage with each other.
Patent CA-3091837-A1 (CA)
Title: Particles comprising polyamides with pendent pigments and related methods
Inventor: FARRUGIA VALERIE M
IPC: C09C3/10
Filed: 2020-09-01
Abstract: A nonlimiting example method of forming polyamide polymer particles having pigments therein may comprising: mixing a mixture comprising a polyamide having a pigment pendent from a backbone of the polyamide (PP-polyamide), a carrier fluid that is immiscible with the PP-polyamide, and optionally an emulsion stabilizer at a temperature greater than a melting point or softening temperature of the PP-polyamide and at a shear rate sufficiently high to disperse the PP-polyamide in the carrier fluid; and cooling the mixture to below the melting point or softening temperature of the PP-polyamide to form solidified particles comprising the PP-polyamide and, when present, the emulsion stabilizer associated with an outer surface of the solidified particles. Said solidified particles may be used in additive manufacturing to make a variety of objects like containers, toys, furniture parts and decorative home goods, plastic gears, automotive parts, medical items, and the like.
Patent CA-3093891-A1 (CA)
Title: Methods and systems for 3d printing with a 3d printing platform including printing tool coupling components
Inventor: CAMBRON SCOTT DOUGLAS
IPC: B33Y10/00
Filed: 2018-10-05
Abstract: Methods and systems for 3D printing use a 3D printing device defined by a polar coordinate frame including an r-axis, z-axis, and rotational theta axis. The device includes a base, a rotatably attached printing stage is rotatably attached, a z-axis aligned pair of towers, an r-axis aligned rail slidably coupled to the towers, a print head slidably disposed on the rail, printing tool coupling component ("master") joined to the print head, and a rotatable tool carousel with bays housing printing tools, each including a printing tool body ("slave"). The slave may be coupled with and locked to or unlocked from the master to form a coupled tool assembly through a mechanical actuation assembly. With the coupled tool assembly, a printing tool is removable from a respective bay when the coupled tool assembly moves along the r-axis in a direction opposite from the rotatable tool carousel.
Patent CA-3094751-A1 (CA)
Title: Puncture mechanism for beverage machine
Inventor: MACLEAN TIMOTHY
IPC: A47J31/36
Filed: 2019-03-22
Abstract: Described herein includes a puncture mechanism for a beverage appliance or machine that can be configured to puncture a pod containing a beverage medium (e.g., a flavoring agent). The puncture mechanism can be configured to induce lateral movement of one or more engagement members to securely hold a beverage pod. The puncture mechanism can be configured to induce relative axial movement between an anvil and the secured beverage pod to puncture a seal of the beverage pod.
Patent CA-3096686-A1 (CA)
Inventor: DOCHERTY JOHN
IPC: A61K31/436
Filed: 2019-04-16
Abstract: Aspects described herein relate to edible compositions and methods for the enhancement of delivery of lipophilic active agents across the blood-brain barrier, particularly wherein the lipophilic active agent infused edible compositions produce greater concentrations of lipophilic active agents in subjects' central nervous system tissues as compared to control compositions. Further provided are methods for treating central nervous system disorders comprising administering the edible compositions to subjects in need thereof.
Patent CA-3097283-A1 (CA)
Title: Jack and tow module for towing a trailer with a truck
Inventor: DAVIS MATT
IPC: B60D1/14
Filed: 2020-10-28
Abstract: A lift and tow module for use with a trailer and method of towing a trailer with a truck. The module has an arm having a connection point for securing to a tow vehicle and a lift body having a connection point for securing the lift body to a trailer. The connection point comprises at least two connection mechanisms spaced apart on the main body for connection to corresponding mechanisms on the trailer. A support plate is extendable from and operably supported by the main body and the lift body is movable in reciprocal directions. Mechanical actuators are operably coupled to the body and the arm for controlling respective movement, which allows the module to jack up a trailer, connect to a trailer, and/or tow a trailer.
Patent CA-3099693-A1 (CA)
Title: Systeme d'allumage de bruleur a induction
Inventor: SIMON PAUL
IPC: F23Q7/02
Filed: 2019-05-06
Abstract: L'invention concerne un système d'allumage de brûleur à induction qui utilise un brûleur à induction situé à l'extérieur du brûlot. Le brûleur à induction peut être commandé par un dispositif de commande pour démarrer et s'arrêter selon un algorithme de chauffage prédéfini et peut en outre fournir de la chaleur par l'intermédiaire de dissipateurs thermiques en contact avec le brûleur à induction. Du fait que le brûleur à induction est situé à l'extérieur du brûlot, il est facilement réparable ou remplaçable et évite l'atmosphère nocive du brûlot. Le brûleur à induction fournit également un chauffage plus uniforme que la technologie de tige chaude classique pour améliorer le processus de chauffage de granules.
Patent CA-3100924-A1 (CA)
Inventor: GODART LUC
IPC: A01C7/04
Filed: 2019-06-11
Abstract: The present invention concerns an assembly (1) for dispensing granular products to be dispensed to the ground, comprising dispensing means (3) for dispensing said granular products in individualised form, conveying means (4) for conveying said individualised granular products to the ground, transfer means (5) for transferring said individualised granular products from the dispensing means (3) to the conveying means (4), characterised in that the transfer means (5) are synchronised in speed and position with the dispensing means (3) and in that the transfer means (5) capture the granular products in an individualised manner and immobilise them within the transfer means (5) so as to keep each granular product spaced apart from each other by a determined and constant distance, in said transfer means (5) and during the transfer of the granular products to the conveying means (4). The invention also relates to a seeding element (24) and a sowing machine comprising the dispensing assembly (1) according to the invention, as well as a method for dispensing granular products to the ground using one or more dispensing assemblies (1), seeding element (24) or sowing machine according to the invention.
Patent CA-3102593-A1 (CA)
Inventor: MULLER RICHARD A
IPC: G21F5/06
Filed: 2019-06-04
Abstract: A canister to store spent nuclear fuel in an underground repository includes a first end portion; a second end portion; and a middle portion attachable to the first and second end portions to define an interior volume of the housing that is sized to enclose at least one spent nuclear fuel assembly. The first and second end portions comprise shielding.
Patent CA-3103545-A1 (CA)
Inventor: BAZZOLI PAOLO
IPC: C12C7/04
Filed: 2019-06-14
Abstract: A process for preparing a cereal-based beverage, the method comprising: ~ providing malt or unmalted cereal grains; ~ mashing said malt or unmalted cereal grains to solubalize fermentable sugars therein the mashing comprising: - a first step wherein the malt or unmalted cereal grains are exposed to protease activity and optionally glucanase activity, the first step being carried out in a temperature interval A; - a subsequent second step wherein the malt or unmalted cereal grains are exposed to beta-amylase and alfa-amylase activity carried out in a temperature interval inhibiting the protease activity of the first step; - filtering the mashed malt or unmalted cereal grains to obtain a wort; - fermenting said wort to obtain the malt-based beverage; wherein the process comprises the addition of malt rootlets to the wort, characterised in that said malt rootlets are added to the malt or unmalted cereal grains during the second step of the mashing process at which protease activity is inhibited.
Patent CA-3104623-A1 (CA)
Inventor: LINDBERG BRAENDON R
IPC: B62D35/00
Filed: 2019-06-21
Abstract: An active aerodynamic application torque link system including a four bar linkage having a fixed link, driven link, follower link and coupler. The fixed link has a follower link aperture and a driven link aperture. The follower link has a first end rotatably connected to the follower link aperture of the fixed link and a second end of the follower link is connected to the coupler. The driven link is rotatably connected at a first end to the coupler and coupled at a second end to a torque transfer tube that has a cross sectional shape of a four sided polygon with four radial facets. The four sided torque transfer tube is rotatably connected to the driven link aperture of the fixed link. The four bar linkage is used in a number of different applications by connecting the coupler with different components.
Patent CA-3105369-A1 (CA)
Inventor: ERMALOVICH JOSEPH
IPC: A61G7/015
Filed: 2019-06-26
Abstract: A compact cartridge fan system for use in an articulating bed structure having a stationary horizontal support panel (20) includes a frame (26) adapted to be engaged in a receiving aperture (29) in the stationary horizontal support panel. A cartridge (30) is removably received in an aperture (28) in the frame. The cartridge has a case (34) containing a box fan (50) and a connector attachment (40). A connector (42) is engaged in the connector attachment and adapted to be received through a mattress base (62) supported on the stationary support panel.
Patent CA-3106976-A1 (CA)
Inventor: MYLES IAN ANTHENI
IPC: A61P17/00
Filed: 2018-11-02
Abstract: Pharmaceutical compositions are disclosed that includes a therapeutically effective amount of a purified viable Gram negative bacteria and a pharmaceutically acceptable carrier. The pharmaceutical compositions are formulated for topical administration. Methods of treating atopic dermatitis using these pharmaceutical compositions are also disclosed.
Patent CA-3110239-A1 (CA)
Title: Smart inhaler device with automated dose delivery, measurement, and management
Inventor: HATAMIAN MEHDI
IPC: A61M15/00
Filed: 2019-08-21
Abstract: A smart inhaler device includes: a flow pathway comprising a cartridge receptacle that is able to house a cartridge, flow meter, pump, and vaporizer; a wireless communication module; and at least one sensor that captures identifying information related to the cartridge. A method of providing a measured dose using a smart inhaler device includes: enabling dosing; measuring a provided dose; and disabling dosing. A smart inhaler system includes: a smart inhaler device; a user device; and a server.
Patent CA-3111640-A1 (CA)
Inventor: OH SOO MI
IPC: H04N19/593
Filed: 2012-11-02
Abstract: ABSTRACT Provided is a method that derives an intra prediction mode of a prediction unit, determines a size of a current block using transform size information, generates a prediction block of the current block according to the intra prediction mode, generating a residual block of the current block according to the intra prediction mode and generating a reconstructed block of the current block using the prediction block and the residual block. The sizes of the prediction block and the residual block are set equal to a size of a transform unit. Therefore, the distance of intra prediction becomes short, and the amount of coding bits of residual block is reduced by generating a prediction block very similar to original block. Also, the signaling 1 0 bits required to signal intra prediction mode decrease by generating MPM group adaptively according to the neighboring intra prediction modes. Date Recue/Date Received 2021-03-09
Patent CA-3112075-A1 (CA)
Title: Fermeture de capuchon par torsion et retournement
Inventor: MIGAS JEREMIAH
IPC: B65D55/16
Filed: 2019-10-10
Abstract: L'invention concerne une fermeture de capuchon par torsion et retournement (10), comprenant des première (12) et deuxième parties de fermeture (14). La première partie de fermeture (10) comporte une partie paroi supérieure (22) et une partie jupe (32). La deuxième partie de fermeture (14) comprend une bande d'inviolabilité (34), ainsi que des premier (50) et deuxième (60) raccords frangibles. Le premier raccord frangible (50) s'étend autour de la circonférence de la fermeture. Le deuxième raccord frangible (60) comporte des première (62) et deuxième (64) parties. Le deuxième raccord frangible (60) est espacé du premier raccord frangible (50). Au moins une partie du deuxième raccord frangible (60) est située plus loin de la partie paroi supérieure (22) qu'une partie du premier raccord frangible (50). Le deuxième raccord frangible (60) définit une zone conçue pour former une languette (70). La fermeture (10) selon l'invention est conçue pour être ouverte par torsion afin de rompre les raccords frangibles (50, 60) et de découvrir la languette (70), puis par retournement de la première partie de fermeture (50) par rapport à la deuxième partie de fermeture (60), par l'intermédiaire de la languette découverte (70). La fermeture (10) selon l'invention est conçue pour être verrouillée lorsqu'elle est retournée.
Patent CA-3113315-A1 (CA)
Title: Procede de positionnement d'une piece et dispositif associe
Inventor: HERTING TORSTEN
IPC: B23Q17/24
Filed: 2019-09-19
Abstract: Selon un mode de réalisation, l'invention concerne un procédé de positionnement précis d'une pièce, en particulier d'une prothèse dentaire (1) dans une machine-outil, le procédé consistant à produire sur une partie pouvant être positionnée avec précision par rapport à la machine une empreinte en un emplacement également connu dans la machine-outil, pour pouvoir agencer la pièce avec précision sur l'empreinte et donc dans la machine-outil pour son usinage. Un dispositif utilisé à cette fin comprend une ébauche (3) et un élément complémentaire (25) sur lequel est formée une empreinte (20). L'ébauche et l'élément complémentaire présentent des structures de clé (9, 10 ; 21, 22) qui permettent de les séparer l'un de l'autre et de les relier à nouveau l'un à l'autre de manière reproductible dans un même agencement. Une variante basée sur des calculs consiste à munir la pièce d'éléments de référencement (41) à déterminer leur position par balayage de la pièce (1), les étapes d'usinage étant produites sur la base du balayage, et à balayer dans une machine-outil la pièce (préparée) sur une ébauche munie de structures de verrouillage (9, 10) dont les coordonnées de machine-outil sont connues, pour déterminer la position de la pièce dans la machine-outil, aussi bien dans des machines-outils que dans les coordonnées d'un système de construction.
Patent CA-3113802-A1 (CA)
Inventor: NUSSENBLATT RICHARD
IPC: C12N5/0783
Filed: 2014-04-22
Abstract: The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age-related macular degeneration and uveitis.
Patent CA-3115380-A1 (CA)
Title: Drawbridge docking system
Inventor: SHAHBAZIAN VAROUJ
IPC: B65G69/28
Filed: 2021-04-16
Abstract: A dockboard featuring a hinged dock plate with a simplified design resembling a draw bridge, with one portion being a stationary dock plate bolted flat on a dock top in an unobstructing disposition, and a second portion being a movable dock plate, fixably connected to the first portion with hinges, which may be raised or lowered to extend or retract a continuous load-supporting floor plane enabling horizontal access from the dock top to the receiving or discharging vehicle. When in an inoperative, retracted position, the second, movable dock plate is circumferentially rotated by means of the hinge connection to rest at a resting position angle of between 60 and 80 degrees from the first, stationary dock plate. When in an operative, extended position, the movable dock plate is circumferentially rotated by means of the hinge connection to rest at a resting position of 180 degrees from the stationary dock plate, forming a continuous plane with stationaly dock plate. The movable dock plate is sloped outward from its connection to the stationary plate, at the hinge, approximately ten degrees over its span, in order to create an easily traversable slope for users. The lip of the movable plate is tapered, in order that it also slope outward at approximately ten degrees over its span, to create an easily traversable slope to the receiving or discharging vehicle.
Patent CA-3116022-A1 (CA)
Inventor: MANSIERE JEFFREY
IPC: C12N5/10
Filed: 2021-04-23
Abstract: Abstract The invention relates to a Canola hybrid variety designated 7CN0065, essentially derived variants of that Canola hybrid variety, to the cells, seeds, plants, and plant parts of this Canola hybrid variety 7CN0065. The invention also relates to methods for producing a canola plant containing in its genetic material one or more traits introgressed into 7CN0065 through backcross conversion and/or transformation, and to the Canola seed, plant and plant part produced thereby. The invention also relates to uses of 7CN0065.   Date Recue/Date Received 2021-04-23
Patent CA-3116162-A1 (CA)
Title: Leveler for tiles
Inventor: CIPRIANI ZENO
IPC: E04F13/08
Filed: 2018-12-04
Abstract: The invention concerns a leveler (10) to make coplanar the faces of two adjacent tiles (P) without using pincers or other tools. The leveler (10) uses a disposable element (12) and a wedge (14) comprising a sawtooth formation thereon cooperating with a tongue on the disposable element, the wedge being adapted to be inserted in the disposable element so as to push down the tiles and make them coplanar.
Patent CA-3116721-A1 (CA)
Inventor: DIAZ-AUNON JOSE A
IPC: B01J20/28
Filed: 2019-10-17
Abstract: Methods for quantifying an amount of exosomes in subject derived biological fluid and comparing to a control provides for a method of identifying a medical condition. Removing an amount of the exosomes by adsorption and binding of the exosomes to an absorbent material, and administering the reconstituted biological fluid comprising a reduced amount of exosomes back to the subject also provides for a method of treating the identified medical condition.
Patent CA-3116855-A1 (CA)
Title: Deep reinforcement learning for production scheduling
Inventor: HUBBS CHRISTIAN
IPC: G06Q10/00
Filed: 2019-09-26
Abstract: Methods and apparatus for scheduling production at a production facility are provided. A model of a production facility utilizing one or more input materials to produce products that satisfy product requests can be determined. Each product request can specify a requested product to be available at a requested time. Policy and value neural networks can be determined for the production facility. The policy neural network can represent production actions to be scheduled at the production facility and the value neural network can represent benefits of products produced at the production facility. The policy and value neural networks can use the model of the production facility during training for generating a schedule of the production actions at the production facility that satisfy the product requests over an interval of time and relates to penalties due to late production of the requested products.
Patent CA-3118234-A1 (CA)
Title: System and method for identifying files based on hash values
Inventor: SALIBA JAD JOHN
IPC: G06F7/00
Filed: 2021-05-13
Abstract: Computer systems and computer-implemented methods for forensically investigating a target dataset including a target file by comparing the target file to a source file are provided. The method includes performing a preliminary matching operation. The preliminary matching operation includes performing at least one of a file size matching operation, in which a target file size is compared to a source file size, and a sub-hash matching operation, in which a target file sub-hash is compared to a source file sub-hash.  A sub-hash is a hash value calculated using a subset of data from the file.  The method further includes performing a full hash matching operation if the preliminary matching operation identifies a preliminary match. The full hash matching operation includes generating a target file full hash value and comparing the target file full hash value to a source file full hash value.
Patent CA-3118520-A1 (CA)
Title: Method for producing erythroid cells
Inventor: GREEN CAROLE
IPC: C07K14/475
Filed: 2019-10-31
Abstract: A method for producing erythroid cells comprising culturing erythroid-producer cells which are obtainable from an EMP3-negative individual, and/or have reduced expression of EMP3 and/or reduced expression of one or more downstream effectors of the EMP3 pathway.
Patent CA-3120459-A1 (CA)
Title: Device for heart repair
Inventor: HIORTH NIKOLAI
IPC: A61F2/24
Filed: 2019-11-29
Abstract: A catheter device is described. The device is for implanting a leaflet anchor (10) into the heart as part of a procedure for implanting an artificial chordae line (14). The catheter device comprises: a leaflet anchor (10) for attachment to the leaflet (12) of the heart; and a leaflet anchor deployment mechanism (6), (30), (38) for deploying the leaflet anchor (10). The leaflet anchor deployment mechanism (6), (30), (38) allows for retraction and repositioning of the leaflet anchor (10) after deployment of the anchor (10) into the leaflet (12) via an ejector unit (36) having a grasping device (50) with a first configuration arranged to permit deployment of the leaflet anchor (10) into the leaflet (12) without disengagement of the leaflet anchor (10) from the ejector unit (34), and a second configuration in which the leaflet anchor (10) is reversibly released from the ejector unit (36). In the first configuration the grasping device (50) of the ejector unit (36) grasps a proximal end of the leaflet anchor (10), whilst a distal end of the leaflet anchor (10) is unimpeded by the grasping device (50) to enable it to be implanted in the leaflet (12). In the second configuration the grasping device (50) is disengaged from the leaflet anchor (10).