baber/WOPTO huggingface dataset:
Patent JP-2641880-B2 (JP)
IPC: C12Q1/68
Filed: 1987-08-11
Granted: 1997-08-20
Abstract: Nucleic acid probe assay methods, particularly sandwich assay methods, and compositions for use therein. The methods of the invention employ novel, oligonucleotide probe-derivatized solid supports, in which oligonucleotide probe, of 15-100 bases in a sequence complementary to a sequence of nucleic acid analyte, is terminally covalently bound. The solid supports of the invention are based on beads of amino-, sulfhydryl, or carboxyl-derivatized controlled pore glass, cyanogen bromide-treated cross-linked dextran, or polystyrene. The linkage between the terminally bound oligonucleotide and the support is effected through these groups, with which the support material is derivatized. The methods of the invention are based on several unexpected discoveries made in the course of investigating the properties of the novel solid supports of the invention: (A) There is little difference between carrying out a sandwich assay by (i) simultaneously hybridizing analyte to solid-support-bound probe and labeled probe in solution and (ii) first hybridizing analyte and labeled probe and then hybridizing analyte to solid support-bound probe. (B) The efficiency of capture of analyte is increased by prehybridizing probe-derivatized solid-support with non-homologous nucleic acid or dextran sulfate or both. (C) The presence of dextran sulfate in a hybridizing solution significantly increases the efficiency of capture of analyte by probe-derivatized solid support. The invention also entails test kits for nucleic acid probe sandwich assays with the solid supports of the invention.
Patent JP-3657619-B2 (JP)
IPC: B05B15/68
Filed: 1996-07-19
Granted: 2005-06-08
Abstract: An optical spray paint optimization system can be removably mounted to a spray paint gun, thus enhancing the ability of the user to guide the direction of the spray and also locate the nozzle at an optimum spray distance from the surface being painted. The preferred apparatus uses a diode laser, a beam splitter and a reflecting mirror to generate a reference beam and a gauge beam. The reference beam propagates in a fixed forward direction, but the direction of the gauge beam is adjustable by adjusting the attitude of the reflecting mirror. The reference beam and the gauge beam intersect at a convergence point which can be repositioned to a selected distance from the nozzle of the spray painting system by adjusting the path of the gauge beam, thus allowing the user to spray at the optimum spray distance by locating the convergence point on the surface being painted. The beams also aid in aiming the spray.
Patent JP-2608082-B2 (JP)
IPC: B65D81/34
Filed: 1987-10-22
Granted: 1997-05-07
Abstract: A food container for use in a microwave oven is disclosed. The container contains a plurality of food substances, and employs a metal shield to shield at least one of the food substances from microwave radiation. Arcing and other problems associated with the use of metal shielding are avoided by proper selection of the geometry of the metal shield. The metal shield is preferably looped in a manner which provides some electrical inductance, and the ends of the metal shield are overlapped and separated by a dielectric material to provide some electrical capacitance. The geometry of the shield is selected so that the inductance and the capacitance in effect form a "tuned circuit" which minimizes problems associated with resonance and which eliminates arcing.
Patent JP-3091218-B2 (JP)
IPC: A61M11/00
Filed: 1990-08-02
Granted: 2000-09-25
Abstract: PCT No. PCT/GB90/01198 Sec. 371 Date Apr. 1, 1992 Sec. 102(e) Date Apr. 1, 1992 PCT Filed Aug. 2, 1990 PCT Pub. No. WO91/03270 PCT Pub. Date Mar. 21, 1991.A nebulizer for liquids, particulate materials or liquids/solids suspensions, comprising, within a vessel (10) containing a reservoir (11), an upright duct (13) with a plurality of circumferentially spaced outlet apertures (20), enclosing a coaxial air line (14) feeding a plurality of jets (16) duly aligned with outlet apertures (20) in the upright duct (13) so that an annular column of material is drawn from reservoir (11) to be dispersed by entrainment in the air streams from the jets (16). Larger droplets may return to the reservoir (11) while the smaller fraction issues from the vessel through an outlet (12). The relatively large outlet apertures (20) and the large cross-sectional area of the column of the material prevent blockage at the nebulizer head.
Patent JP-2642244-B2 (JP)
IPC: C07D217/20
Filed: 1992-12-12
Granted: 1997-08-20
Abstract: PCT No. PCT/EP92/02900 Sec. 371 Date Aug. 18, 1994 Sec. 102(e) Date Aug. 18, 1994 PCT Filed Dec. 12, 1992 PCT Pub. No. WO93/13073 PCT Pub. Date Jul. 8, 1993.Tetrahydroisoquinoline compounds of formula I    <IMAGE>  I  and pharmaceutically acceptable salts and lipophilic ester thereof have utility as analgesics and in the treatment of psychoses, Parinson's disease, Lesch-Nyan syndrome, attention deficit disorder or cognitive impairment or in the relief of drug dependence or tardive dyskinesia.
Patent JP-4098828-B2 (JP)
IPC: A61K31/454
Filed: 1996-09-25
Granted: 2008-06-11
Abstract: Compounds having the formula:   <IMAGE>   wherein W is the same at each occurrence and is selected from optionally substituted quinolyl, optionally substituted benzothiazolyl, optionally substituted benzoxazolyl, optionally substituted benzimidazolyl, optionally substituted quinoxalyl, optionally substituted pyridyl, optionally substituted pyrimidyl, and optionally substituted thiazolyl; R1 and R2 are independently selected from hydrogen, alkyl, halolalkyl, alkoxy, halogen; R3 is a valence bond or is selected from hydrogen and alkyl; X is a valence bond or is selected from alkylene, alkenylen, and alkynylene; and Z is selected from (a) COM, (b) CH=N-O-A-COM, (c) CH2-O-N=A-COM wherein A is selected from alkylene and cycloalkylene, and M is selected from (a) a pharmaceutically acceptable metabolically cleavable group, (b) -OR6, (c) -NR7R8, (d)-NR6SO2R9, (e)-NH-Tetrazolyl, and (f) glycinyl inhibit leukotriene biosynthesis and are useful in the treatment of allergic and inflammatory disease states. Also disclosed are leukotriene biosynthesis inhibiting compositions and a method of inhibiting leukotriene biosynthesis.
Patent JP-3669704-B2 (JP)
IPC: G16B15/30
Filed: 1995-10-30
Granted: 2005-07-13
Abstract: A method of searching one or more ligand-candidate compounds to a target biopolymer from a three-dimensional structure database, which comprises the steps of: (i) the first step of assigning hydrogen-bonding category numbers, information for calculating force-field energy, and information for generating conformations to two or more trial compounds in addition to atomic three-dimensional coordinates thereof; (ii) the second step of preparing physicochemical information about a ligand-binding region and one or more dummy atoms based on the three-dimensional atomic coordinates of the target biopolymer;(iii) the third step of estimating the most stable docking structure, wherein said step further comprises the steps of examining possible docking structures by docking a trial compound to the biopolymer while varying conformations of the trial compound, evaluating interaction energies between the target biopolymer and the trial compound, and repeating structure optimization; (iv) the fourth step of deciding whether or not the trial compound should be adopted as a ligand-candidate compound based on given criteria including the interaction energy values between the target biopolymer and the trial compound in the most stable docking structure estimated according to the step (iii); and (v) the fifth step of repeating the step (iii) and the step (iv) for all of the trial compounds.
Patent JP-3417945-B2 (JP)
IPC: A61G7/05
Filed: 1993-04-14
Granted: 2003-06-16
Abstract: An infusion delivery system eliminates the requirement for individual "smart pump" assemblies each of which includes a processor, power supply and operator I/O for each IV container suspended on an IV rack. An acquisition module capable of supporting multiple IV containers is suspended from the hospital bed frame and includes a plurality of ports into which a connector is inserted for controlling a dumb pump on each IV container. The acquisition module includes a processor, power supply and operator input/output mechanism for programming the delivery schedule for each of several IV containers. The dumb pump on each IV container includes only the mechanical components required for pumping the IV fluid to the patient. The infusion delivery system thus provides a less cluttered, more compact, and economical delivery system for IV fluids compared to the prior art.
Patent JP-3258668-B2 (JP)
IPC: F23C10/24
Filed: 1996-01-04
Granted: 2002-02-18
Abstract: A fluidized bed assembly, such as an ash cooler, includes first and second fluidized bed chambers each having a bottom portion and side walls. Fluidizing gas is introduced into the bottom portions to fluidize particulates within the chambers. A flow equalizer (such as a barrier having a number of openings associated with it) separates the chambers and provides a substantial uniform flow of particulates from the first chamber to the second chamber so that no dead spots or corners form in the chambers adjacent the flow equalizer. Heat exchanger components are typically provided in the barrier for circulating heat exchange fluid through the barrier. Also, heat exchangers are provided in one or both of the chambers to cool the particulates. The particulates mix in the second chamber, and after cooling may be recirculated to a gasifier/combustor for supplying ash to the first chamber. A classifier chamber is connected between the reactor and the first chamber. Fluidizing gas may be returned from the chambers to the reactor.
Patent JP-4012251-B2 (JP)
IPC: A61F2/82
Filed: 1997-04-25
Granted: 2007-11-21
Abstract: The stent in a non-expanded state has a first column expansion strut pair. A number of the first column expansion strut pair form a first expansion column. A number of second column expansion strut pair form a second expansion column. A number of first serial connecting struts form a first connecting strut column that couples the first expansion column to the second expansion column. The first expansion column, the second expansion column, and the first connecting strut column form a number of geometric cells. At least a portion the number are asymmetrical geometric cells.
Patent ES-2277746-B2 (ES)
Title: "equipo en linea de carga para la clasificacion, salado y doblado de pieles".
Inventor: SOLER VALERA JUAN
IPC: B65H45/02
Filed: 2005-06-16
Granted: 2008-06-16
Abstract: Equipo en línea de carga para la clasificación, salado y doblado de pieles que comprende una cinta de comprobación (1) manejada por el operario (2) montada sobre el bastidor (3) y apoyada sobre las patas (4), cuya cinta de comprobación (1) dispuesta en posición inclinada, es accionada por un motorreductor con varillador de velocidad llevando una bandeja antiarrastre y una botonera manipulable, pasando la piel (11) seleccionada a las cintas de doblado (5) sobre las que se disponen los soportes (6) de los grupos neumáticos (7) dentro de la cavidad (10) entre las cintas de doblado (5), pasando la piel plegada sobre la cinta inferior de acunado (12), pasando de ésta al palet (13), dispuesto dentro del espacio (14), llevando a ambos lados de la cinta (12) unos perfiles (15) accionados por husillos para elevar la plataforma, saliendo las pieles desechadas por la rampa (16) en los espacios (17) y (18) cayendo dentro del receptáculo (19) sobre el vehículo (20).
Patent ES-2447340-B2 (ES)
Title: Aparato y procedimiento para enviar eficientemente mensajes de activación de dispositivo
Inventor: RAO VARUN
IPC: H04W52/02
Filed: 2013-07-02
Granted: 2015-09-29
Abstract: Aparato y procedimiento para enviar eficientemente mensajes de activación de dispositivo.#Con la proliferación de la Comunicación Tipo Máquina (MTC), un uso excesivo de mensajes de activación de dispositivo en una red de Evolución a Largo Plazo (LTE) puede tener efectos negativos sobre el equipo de usuario (UE). Estos efectos pueden incluir un acortamiento de la duración de la batería del UE y/o excesiva señalización causada por el cambio frecuente de un modo inactivo a un modo activo. Una Función de Interfuncionamiento de MTC (MTC-IWF) puede ser configurada para determinar el estado de un UE para el que está destinado un mensaje de activación de dispositivo. Si el mensaje de activación de dispositivo es de baja prioridad y el UE está en un estado inactivo, la MTC-IWF o la Entidad de Gestión de la Movilidad (MME)/el Nodo de Soporte GPRS de Servicio (SGSN)/el Centro de Conmutación de Servicios Móviles (MSC) pueden almacenar temporalmente el mensaje de activación de dispositivo.
Patent AU-2002212810-B2 (AU)
Title: Transportation system with linear motor
Inventor: TENT BEREND
IPC: H02K41/03
Filed: 2001-09-14
Granted: 2005-07-14
Abstract: Transportation system comprising a large number of platforms which can be displaced along guides and a smaller number of displacement devices which can be coupled to and uncoupled from the said platforms. Each displacement device comprises a linear actuator comprising a moving part and a stationary part. The stationary part comprises a laminated plate assembly with coils, and the moving part comprises a structure with permanent magnets, such as neodymium magnets. On the linear actuator, there may be a further linear actuator, so that movement in two directions is possible. A transportation system of this type can be used in a parking garage for positioning vehicles.
Patent AU-2002239407-B2 (AU)
Title: DNA methyl transferase inhibitors
Inventor: SHIER VINCENT K
IPC: C07F5/02
Filed: 2001-11-29
Granted: 2007-12-06
Abstract: This invention provides broad-spectrum antibiotics that are inhibitors of bacterial adenine DNA methyltransferases.
Patent AU-2002341728-B2 (AU)
Title: Providing an image on an organic product
Inventor: WALKER ROLAND N
IPC: G03F1/00
Filed: 2002-09-19
Granted: 2007-12-20
Abstract: Systems and methods for providing an image on an organic product to provide a communication to the recipient or otherwise individualize the organic product. The image is photo-etched into a photosensitive material of a printing plane or cliché by the use of a film positive. Ink is applied to the cliché and a transfer medium is placed in contact with the cliché. The transfer medium lifts ink from the image area of the cliché and creates a negative image on the medium. The transfer medium transfers the inked image onto an organic product, such as a flower petal or leaf. The printed image is then set so as to remain on the organic product to communicate a message to and/or to individualize the product for the intended recipient.
Patent AU-2002354047-B2 (AU)
Title: Recombinant antibodies for the detection and neutralization of anthrax toxin
Inventor: MAYNARD JENNIFER A
IPC: C07K16/12
Filed: 2002-11-05
Granted: 2007-11-22
Abstract: A composition and method for treating a host having or at risk of infection by Bacillus anthracis using an affinity matured antibody or portion thereof derived from a monoclonal antibody.
Patent AU-2004210096-B2 (AU)
Title: Spray gun and process for application of actinic radiation-curable coating
Inventor: JONKER JOSEF PANCRATIUS MARIA
IPC: B05B17/04
Filed: 2004-02-04
Granted: 2009-04-02
Abstract: The invention relates to a spray gun for application of a coating having a spray nozzle and at least one actinic radiation outlet, characterized in that the at least one actinic radiation outlet is positioned externally and the radiation outlet and the spray nozzle are simultaneously directable to a substrate to be coated, and to a process of applying a coating composition which is at least partly curable by actinic radiation. The spray gun according to the invention is suitable for all types of actinic radiation-curable coating compositions, even if there is no induction period between the initiation by actinic radiation and the actual onset of the curing reaction. The balance of flow of the coating material just after application and the drying speed are particularly favourable.
Patent AU-2004224087-B2 (AU)
Title: Pyrroloimidazole derivatives, their preparation, pharmaceutical composition containing them, and their use as nootropic agents
Inventor: PARINI CARLO
IPC: C07D487/04
Filed: 2004-03-22
Granted: 2010-04-01
Abstract: Described herein are new bicyclic arylimidazolones having nootropic action (i.e., protecting and stimulating cerebral functions), analgesic action and anti hyperalgesic action; also described is the process for their preparation and pharmaceutical compositions comprising them, useful for the treatment of cognitive deficits, and of various types of pain.
Patent AU-2004224809-B2 (AU)
Title: Disposable packaging for the distribution of a liquid preparation pumped by a venturi-effect device
Inventor: KLOPFENSTEIN ANDRE
IPC: A47J31/44
Filed: 2004-03-17
Granted: 2010-01-28
Abstract: The package has a closed storage containing pumpable dietary liquid e.g. milk. A collecting unit collects a sub-set of suction and mixture of venture type and a sealing unit seals the package. A stack crossing bottom (7) and a lid, collects dietary liquid within the package by piercing or by removing lid. The sealing unit cooperates in an open manner with the suction and mixture sub-set in a passage of the collecting unit. An independent claim is also included for a method of production and distribution of a preparation in a hygienic manner.
Patent AU-2004259205-B2 (AU)
Title: Devices and methods for percutaneously treating aortic valve stenosis
Inventor: LAIRD ROB
IPC: A61F2/958
Filed: 2004-07-16
Granted: 2009-04-23
Abstract: Devices and methods for their use in percutaneously increasing the aortic valve flow of a stenotic aortic valve are provided. The subject devices include an aortic valve isolation element, a shunt element and an aortic valve flushing element. Also provided are systems and kits that include the subject devices and can be employed in practicing the subject methods. The subject devices, methods, systems and kits find use in treating conditions associated with the presence of stenotic aortic valves.
Patent AU-2005224066-B2 (AU)
Title: Solid-liquid filtration cloth and filtering device
Inventor: RAUTANEN AIMO
IPC: D03D15/567
Filed: 2005-03-21
Granted: 2010-02-11
Abstract: The invention relates to a method of making a solid-liquid filtration cloth, a solid-liquid filtration cloth, and a filter in which the solid-liquid filtration cloth is arranged. The filter cloth (7) is provided with yarns (13b) having a highly changing length and a long free run in the weave. When the length of the yarns (13b) is allowed to shorten significantly, a filtration portion (15) on the side of a surface (14) of the cloth obtains a corrugated shape, providing the cloth with a large filtering area.
Patent AU-2005234486-B2 (AU)
Title: Data monitoring and recovery
Inventor: SCHREIBER JEFFREY B
IPC: G01S1/00
Filed: 2005-04-12
Granted: 2009-06-04
Abstract: In one embodiment, a method for DMR includes generating first tracking reports of first data units received at one or more receptors from one or more remote units, generating second tracking reports of first data units received at one of one or more centrals, and generating delivery reports of second data units extracted at the central from the first data units received at the central. The method includes, using the delivery reports, identifying missing second data units that should have been received at the central, but were not. The method includes, using one or more of the tracking reports, mapping the missing second data units to one or more first data units and determining a best source for retransmission of the first data units mapped to the missing second data units. The method includes generating a retransmit request for the first data units mapped to the missing second data units and communicating the retransmit request to the best source.
Patent AU-2005273880-B2 (AU)
Title: Foamed glass cooling run
Inventor: WALTER FRANK
IPC: C03B19/08
Filed: 2005-08-18
Granted: 2011-07-07
Abstract: The invention relates to a device and a method for the continuous production of one-piece foamed glass sheets, whereby the foamed glass is foamed from glass particles and a blowing agent with a thermal treatment to give an endless foamed glass web (16) and, directly after foaming, the foamed glass web (16) is continuously cooled to room temperature at such a rate that the foamed glass has a stress-free structure made up of glass and a number of pores.
Patent AU-2005284711-B2 (AU)
Title: 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
Inventor: RUI ZHANG
IPC: C07C59/68
Filed: 2005-09-14
Granted: 2011-09-29
Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
Patent AU-2005286914-B2 (AU)
Title: Expandable impeller pump
Inventor: WALSH JUSTIN M
IPC: A61M60/808
Filed: 2005-09-16
Granted: 2012-03-08
Abstract: An impeller according to an example of the present invention comprises a hub, and at least one blade supported by the hub. The impeller has a deployed configuration in which the blade extends away from the hub, and a stored configuration in which the impeller is radially compressed, for example by folding the blade towards the hub. The impeller may comprise a plurality of blades, arranged in blade rows, to facilitate radial compression of the blades. The outer edge of a blade may have a winglet, and the base of the blade may have an associated indentation to facilitate folding of the blade.
Patent AU-2005310983-B2 (AU)
Title: Cache for an enterprise software system
Inventor: CLISBY PETER LEE
IPC: G06Q10/00
Filed: 2005-11-15
Granted: 2009-11-05
Abstract: Techniques are described for caching data from a software system, such as an enterprise software system. The techniques may be applied to a computing device connected to the software system via a network. In one example, the cache comprises an elegant, file-based cache that includes an object store that stores the cached data and an allocation table that manages allocation of space in the object store. The caching techniques provide a robust storage system which preserves a previous copy of the allocation table while updating the current table. Moreover, cache management techniques are described that utilize an automatic collapse to keep cache file sizes to a minimum. When multiple software applications are executing on the computing device, the techniques allow concurrent access to the cache by the multiple software applications while maintaining the integrity of the stored data.
Patent AU-2005315438-B2 (AU)
Title: Transgenic animals for assessing drug metabolism and toxicity
Inventor: FAUST NICOLE
IPC: G01N33/50
Filed: 2005-12-13
Granted: 2012-02-23
Abstract: The present invention relates to transgenic non-human animals, tissues or cells derived therefrom and methods of producing them. The transgenic non-human animals or tissues or cells derived therefrom provide a system capable of expressing human proteins responsible for drug metabolism in place of the homologous endogenous non-human animal proteins and for the controlled expression of human genes introduced into the animal so that the expression of the human genes is regulated in a manner more closely analogous to that seen in humans.
Patent AU-2006222252-B2 (AU)
Title: Pyrazine -2-carboxamide derivatives as mGluR5 antagonists
Inventor: KOLCZEWSKI SABINE
IPC: C07D241/26
Filed: 2006-03-02
Granted: 2012-02-16
Abstract: The present invention is concerned with novel pyrazine 2-carboxyamide derivatives of the general formula (I) useful as metabotropic glutamate receptor antagonists: formula (I) wherein R, R and R are as defined in the description and claims.