Patent GB-942305-A (GB)
Title: Improvements in or relating to antiseptic film and method and apparatus for producing the same
IPC: A61L26/00
Filed: 1959-12-18
Abstract: A film-like bandage adapted to hold medicaments and release them to the skin when used thereon comprises a water soluble, flexible, self-supporting, thin air-transmitting porous, hemostatic sheet, soluble in plasma and other liquids at body temperature after application to the skin, of substantially uniform thickness, of a cellulose ether selected from carboxyl alkyl celluloses and hydroxy alkyl celluloses and alkali metal salts thereof and a plasticizer therefor, the sheet having been produced from an aqueous solution containing the cellulose ether and plasticizer. The ether is preferably carboxy methyl cellulose, hydroxy ethyl cellulose or sodium carboxy methyl cellulose. The plasticizer may be glycerol, diglycerol, glycerol and monomethyl ether, glycerol monochlorohydrin, 1,2,6-hexanetrive, ethylene glycol, propylene glycol, 2-3,butylene glycol, 2-nitro -2- methyl - 1,3, propane diol, 2,21-dihydroxy diethylamine, or 2-hydroxy ethylamine.  The bandage may also contain one or more medicaments, germicides, antiseptics or antibiotics such as sulpha drugs, sulphanilamides, sulphathiazoles, sulphadiazines, solicylates or iodine. The bandage may be obtained by forming an aqueous solution of the ether and plasticizer, applying the solution on to the surface of a moving belt having a polytetrafluoroethylene surface, and heating the solution on the belt to form a dried film which is subsequently removed. The cellular product may be free from air or may contain 30-40% of air in the form of very small bubbles.ALSO:A film-like bandage adapted to hold medicaments and release them to the skin when used thereon comprises a water-soluble, flexible, self-supporting, thin air-transmitting porous, hemostatic sheet, soluble in plasma and other liquids at body temperature after application to the skin, of substantially uniform thickness, of a cellulose ether selected from carboxy alkyl celluloses and hydroxy alkyl celluloses and alkali metal salts thereof and a plasticizer therefor.  The sheet having been produced from an aqueous solution containing the cellulose ether and plasticizer.  The ether is preferably carboxy methyl cellulose, hydroxy ethyl cellulose or sodium carboxy methyl cellulose.  The plasticizer may be glycerol, diglycerol, glycerol and monomethyl ether, glycerol monochlorohydrin, 1,2,6-hexanetrol, ethylene glycol, propylene glycol, 2,3-butylene glycol, 2-nitro-2-methyl-1,3, propane diol, 2,21-dihydroxy diethylamine, or 2-hydroxy ethylamine.  The bandage may also contain one or more medicaments, germicides, antiseptics or antibiotics such as sulpha drugs, sulphanilamides, sulphathiazoles, sulphadiazines, salicylates or iodine.  The bandage may be obtained by forming an aqueous solution of the ether and plasticizer, applying the solution on to the surface of a moving belt having a polytetrafluoroethylene surface, and heating the solution on the belt to form a dried film which is subsequently removed.  The cellular product may be free from air or may contain 30-40% air in the form of very small bubbles.