baber/WOPTO huggingface dataset:
Patent NZ-522547-A (NZ)
Title: Nucleic acid encoding ens-1 a polypeptide expressed by pluripotent cells, particularly avian cells
Inventor: ACLOQUE HERVE
IPC: A61K45/00
Filed: 2001-04-19
Abstract: An isolated nucleic acid comprises the nucleic acid sequence of SEQ ID NO:1 and a polypeptide comprises the sequence of SEQ ID NO:2. The nucleic acid is expressed by pluripotent cells. The pluripotent nature of avian ES cells can be determined by detecting the presence of a product of expression of the gene corresponding to SEQ ID NO:1. Also described are methods for screening for a substance or medium capable of inducing differentiation of pluripotent cells, or for a substance capable of restoring the pluripotent nature of differentiated cells.
Patent NZ-528406-A (NZ)
Title: Pyridazinone aldose reductase inhibitors
Inventor: MYLARI BANAVARA LAKSHMAN
IPC: C07D307/82
Filed: 2002-01-31
Abstract: Aldose reductase inhibitor compounds of formula (I), and the use thereof to treat cardiac tissue ischemia.
Patent NZ-531616-A (NZ)
Title: Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
Inventor: PINTO DONALD
IPC: A61P7/02
Filed: 2002-09-17
Abstract: Disclosed is a compound of formula I wherein ring M is a ring of formula II and ring P is of the structure formula III and the remaining substituents are as defined in the specification. Compounds as disclosed are useful in the treatment of thromboembolic disorders.
Patent NZ-533060-A (NZ)
Title: Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
Inventor: DONG LIANG C
IPC: A61K38/43
Filed: 2002-12-18
Abstract: Disclosed is a formulation and dosage form for enhancing the bioavailability of orally administered hydrophilic macromolecules. The formulation of the present invention includes a permeation enhancer, a hydrophilic macromolecule, and a carrier that exhibits in-situ gelling properties, such as nonionic surfactant. The formulation of the present invention is delivered within the GI tract as a liquid having at least some affinity for the surface of the GI mucosal membrane. Once released, it is believed that the liquid formulation spreads across one or more areas of the surface of the GI mucosal membrane, where the carrier of the formulation then transitions into a bioadhesive gel in-situ. As a bioadhesive gel, the formulation of the present invention present the hydrophilic macromolecule and the permeation enhancer at the surface of the GI mucosal membrane at concentrations sufficient to increase absorption of the hydrophilic macromolecule through the GI mucosal membrane over a period of time. The dosage form of the present invention incorporates the formulation of the present invention and may be designed to provide the controlled release of the formulation within the GI tract over a desired period of time.
Patent NZ-534205-A (NZ)
Title: Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins
Inventor: GRAWUNDER ULF
IPC: C12N15/09
Filed: 2001-12-22
Abstract: Disclosed is a method for the generation of vertebrate lymphocytes that can be used for the production of any antibody or binding protein or functional fragment(s) thereof with the ability to selectively bind to an antigen or ligand, comprising the steps of: a) genetically modifying vertebrate precursor lymphocytes, which are derived from primary lymphoid organs, and have the potential to differentiate into mature lymphoid linage cells, by introducing at least one exogenous genetic element encoding at least one antibody, binding protein of functional fragment thereof; and b) effecting differentiation of said genetically modified precursor lymphocytes into mature lymphoid lineage cells either in vitro or in vivo thereby generating lymphocytes capable of producing said binding protein or antibody or functional fragment thereof. Included in the definition of a binding protein is any heterologous antibody, any antigen receptor composed of variable domains and constant regions comprising T cell receptors and membrane bound immunoglobulins.
Patent NZ-539801-A (NZ)
Title: Crystal forms of azithromycin
Inventor: LI ZHENG JANE
IPC: A61K9/28
Filed: 2002-05-01
Abstract: Disclosed is a crystalline form of azithromycin, which is substantially pure crystalline azithromycin monohydrate hemi-ethanol solvate. Also disclosed is a method of preparing the above form, comprising: (a) dissolving azithromycin in 1-3 volumes ethanol, at 50-70C, (b) completely dissolving the above azithromycin in ethanol, (c) cooling to cause precipitation, (d) collecting azithromycin crystalline, and (e) drying the azithromycin crystalline to obtain the crystalline form. (62) Divided Out of 529118
Patent NZ-541013-A (NZ)
Title: A composition comprising a polypeptide comprising SEQ ID NO:577 for use in treating chlamydial infection
Inventor: FLING STEVEN P
IPC: A61K38/00
Filed: 2001-07-20
Abstract: A composition comprising a polypeptide comprising the sequences of SEQ ID NO:577 or a polynucleotide encoding the polypeptide for use in stimulating an immune response or treating or preventing chlamydial infection. Also disclosed is a vaccine comprising the composition and the use of the composition in the manufacture of a medicament.
Patent NZ-541594-A (NZ)
Title: Anti-viral 4'-substituted nucleoside analogs and methods for treating viral infections, especially HIV infections
Inventor: TANAKA HIROMICHI
Filed: 2004-02-18
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification. The compounds are useful for the treatment of viral infections, including retroviruses such as HIV.
Patent NZ-547586-A (NZ)
Title: Built-in light
Inventor: ENGEL HARTMUT S
IPC: F21V3/00
Filed: 2004-11-24
Abstract: A built-in lamp comprising a holder for fastening in an installation surface a bulb 6 and a reflector 4, with a reflector 4 opening disposed in the direction of illumination defining a direct light discharge region 1, which is surrounded by a diffuse light discharge region 1 such that scattered light is discharged from the diffuse light discharge region 1 around the direct light discharge region 1, wherein the bulb 6 and the direct light reflector 4 are arranged in a housing 10 whose inner surface is made at least regionally as an additional reflector 7; and in that the housing 10 is terminated in at least a largely dust-proof manner by a translucent scattering plate 8 in the region of the diffuse light discharge region 1 and by a plate 13 in the region of the direct light discharge region 1.
Patent NZ-547913-A (NZ)
Title: Apparatus, method and system for providing next generation communication services over existing wiring
Inventor: AWATERE DAVID HEMI
Filed: 2006-06-14
Abstract: An apparatus for providing a next-generation communication system over existing wiring is disclosed. The apparatus includes an input to receive broadband signals carrying next-generation communication data, a processor to extract the next-generation communication data from the broadband signals and a converter to convert the next-generation communication data into analogue telephone signals. The apparatus is arranged to output the analogue telephone signals at the input of the apparatus. Also disclosed is a related method of providing a next-generation communication system over existing wiring.
Patent NZ-562668-A (NZ)
Title: Tobacco pouch product
Inventor: WINTERSON WARREN D
IPC: A24B13/00
Filed: 2006-04-28
Abstract: A pouched tobacco product comprises a lined pouch material comprising of a web 130, a water-soluble liner 120 adjacent to the web 130, and tobacco (110) contained within the lined pouch material. The liner reduces staining of the web by the tobacco.
Patent NZ-565615-A (NZ)
Title: Waste container apparatus
Inventor: WEBSTER YVONNE JEAN
IPC: E03C1/12
Filed: 2005-05-25
Abstract: A waste container apparatus comprising an outer container and an inner container, an inlet adapted to direct fluid and non-fluid waste from outside the apparatus into the inner container, and an outlet adapted to direct fluid waste away from the apparatus, the inner container including one or more apertures adapted to in use allow fluid waste to pass therethrough into the outer container while substantially capturing non-fluid waste within the inner container and means to allow removal of the non-fluid waste captured therein, and a direct fluid waste conduit aligned in use with the inlet. (62) Divided Out of 540286
Patent NZ-567547-A (NZ)
Title: Combinations comprising 6-hydroxy-8-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1,1-dimethyl-ethylamino]-ethyl}-4H-benzo[1,4]oxazine-3-one and tiotropium salts, for the treatment of respiratory disorders
Inventor: BOUYSSOU THIERRY
IPC: A61K31/538
Filed: 2006-10-06
Abstract: Disclosed is a medicament combination comprising 6-hydroxy-8-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1,1-dimethyl-ethylamino]-ethyl}-4Hbenzo[1,4]oxazin-3-one (1.1), and a tiotropium salt (2.1), where the molar ratio of the active substances 1.1 to 2.1 is in the range from 1:1 to 10:1. Also disclosed is the use of the above combination for treating inflammatory and obstructive respiratory complaints, for inhibiting premature labour in midwifery (tocolysis), for restoring sinus rhythm in the heart in atrioventricular block, for correcting bradycardic heart rhythm disorders (antiarrhythmic), for treating circulatory shock (vasodilatation and increasing the heart volume) as well as for the treatment of skin irritations and inflammation.
Patent NZ-567560-A (NZ)
Title: Conveyance device for traveling along a surface and conveying an explosive charge
Inventor: GRUNDLINGH LLEWELLYN JOHN
IPC: B65G35/00
Filed: 2006-10-10
Abstract: A conveyance device, suitable for travelling along a surface, is disclosed. The conveyance device includes a propulsion member (20, 22) having two opposite ends (24). The propulsion member is displaceable between a longitudinally extended position where the ends are displaced away from one another, and a longitudinally contracted position where the ends are displaced towards one another. An outer gripping member (30) and an inner gripping member (40) are displaceable between a circumferentially expanded position where an outer perimeter of the gripping member (30,40) is displaced away from a centre of the member so as to, in use, abut at least part of the surface, and a circumferentially contracted position where an outer perimeter of the gripping member is displaced towards the centre of the member so as to be spaced apart from the surface. The propulsion member (20, 22) and gripping members are configured in order for sequential displacement of the propulsion member and gripping members to result in peristaltic displacement of the conveyance device (10) relative to the surface.
Patent NZ-567807-A (NZ)
Title: Novel herbicide (2,4-D and pyridyloxyacetate) resistance genes with aryloxyalkanoage dioxygenase activity
Inventor: LIRA JUSTIN M
IPC: C12N5/04
Filed: 2006-10-27
Abstract: Provided is a transgenic plant cell comprising a polynucleotide that encodes an having aryloxyalkanoate dioxygenase AAD-12 protein with a specified sequence of a variant thereof having at least 95% sequence identity wherein said polynucleotide imparts to said cell an ability to convert a phenoxyacetate auxin herbicide to a non-herbicidal molecule.or a pyridyloxy auxin herbicide to a non-herbicidal molecule. Further provided are transgenic plants comprising such cells and their progeny.
Patent NZ-576663-A (NZ)
Title: Low dust gypsum wallboard
Inventor: YU QIANG
IPC: B32B13/00
Filed: 2007-10-09
Abstract: Disclosed is a gypsum wallboard including: a set gypsum core formed between two substantially parallel cover sheets, the set gypsum core having a total void volume from about 75% to about 95%, with at least 60% of the total void volume comprising air voids having an average diameter greater than about 10 microns and at least 10% of the total void volume comprising water voids having an average diameter less than about 5 microns, wherein the air and water voids in the set gypsum core are substantially evenly distributed throughout the set gypsum core composition; and the set gypsum core being made from a gypsum-containing slurry including water, stucco, pregelatinized starch, and a naphthalenesulfonate dispersant, wherein the pregeIatinized starch is present in an amount from about 0.5% by weight to about 10% by weight based on the weight of stucco.
Patent NZ-579288-A (NZ)
Title: Methods of activating irs-1 and akt
Inventor: REAUME ANDREW G
IPC: A61K31/54
Filed: 2008-07-22
Abstract: Disclosed are methods of activating IRS-1 and/or AKT and methods of treating or preventing IRS-1- and/or AKT-related disease, condition, or disorder.
Patent NZ-587740-A (NZ)
Title: Concrete tower where the compressive strength of concrete is increased with height by increasing the density of the concrete
Inventor: STIESDAL HENRIK
IPC: E04C5/08
Filed: 2010-09-01
Abstract: A concrete tower for a wind turbine is disclosed. In a tower, the compressive strength of the concrete increases and the cross-section area of the tower decreases with its height. The decrease in the cross-sectional area is compensated for with the increase in the compressive strength of the concrete. The compressive strength of the concrete is increased by increasing the density of the concrete.
Patent NZ-591098-A (NZ)
Title: Engineered anti-il-13 antibodies, compositions, methods and uses
Inventor: SWANSON RONALD V
IPC: A61K39/395
Filed: 2009-08-11
Abstract: Disclosed are engineered antibodies immunospecific for human interleukin-13 (IL- 13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
Patent NZ-591435-A (NZ)
Title: Non-welded reinforcing wire mesh
Inventor: MCKENZIE MAURICE JOHN
IPC: B21F27/08
Filed: 2009-08-28
Abstract: Disclosed is a concrete reinforcement mesh for improved handling and placement. The mesh comprises intersecting longitudinal and transverse wires having an outer perimeter, each intersect inward of the perimeter defining a node and each longitudinal wire having a higher tensile strength than the transverse wire. A binding wire is present at a majority of the nodes to attach the intersecting transverse and longitudinal wires at that node. The transverse wires are more closely spaced than the longitudinal wires such that the tensile load capability of a square metre of mesh is substantially the same in both longitudinal and transverse directions. The longitudinal wires have a diameter between 2 and 3.85 mm and the transverse wires have a diameter between 2 and 3.85 mm. The longitudinal wire has an ultimate tensile strength of about 1050 to 1550 MPa and the transverse wire has an ultimate tensile strength of about 750 to 1050 MPa,
Patent NZ-596915-A (NZ)
Title: Fluid dispenser for treatment of animal flea infestation
Inventor: FOWLER JOHN EDWARD FOX
IPC: A61D7/00
Filed: 2011-12-06
Abstract: Disclosed is a fluid applicator to allow measured dose application of medicaments. The fluid applicator, including a cylindrical tube body with a fluid reservoir, and a plunger with a threaded shaft that moves through the reservoir, a plunger actuator that when twisted or rotated around the threaded shaft moves the plunger linearly to force fluid through the resilient thermoplastic rubber applicator nozzle with an angled face containing an outlet slit. The actuator includes a nut or ratchet with a thread complementary to the screw thread of the shaft of the plunger and the interior of the body is provided with a plurality of protrusions dimensioned to contact the nut or ratchet of the actuator. The applicator includes marking or indicia for volume measurement.
Patent NZ-598582-A (NZ)
Title: Novel phenol derivative having uricsuric effect
Inventor: KOBASHI SEIICHI
IPC: A61K31/428
Filed: 2010-09-29
Abstract: Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a phenol derivative represented by general formula (1) that is shown in Fig. 1; a pharmaceutically acceptable salt thereof; a hydrate of the derivative or the salt; and a solvate of the derivative or the salt. In the formula, R1 and R2 may be the same or different and each represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, a haloalkyl group, a haloalkoxy group, an alkylsulfanyl group, an alkylsulfinyl group, an alkylsulfonyl group, a lower alkyl-substituted carbamoyl group, a saturated nitrogen-containing heterocyclic N-carbonyl group, a halogen atom, a cyano group or a hydrogen atom; R3 represents a lower alkyl group, a haloalkyl group, a halogen atom, a hydroxy group or a hydrogen atom; and X represents a sulfur atom, an -S(=O)- group or an - S(=0)2- group.
Patent NZ-611468-A (NZ)
Title: Humanized antibodies to liv-1 and use of same to treat cancer
Inventor: SMITH MARIA LEIA
IPC: C12P21/08
Filed: 2011-12-06
Abstract: Disclosed is a humanised antibody comprising a mature heavy chain variable region having an amino acid sequence at least 90 % identical to SEQ ID NO:53 provided that position H27 is occupied by L, position H29 is occupied by I, H30 by E and H94 by V and a mature light chain variable region at least 90 % identical to SEQ ID NO:60 provided position L36 is occupied by Y and position L46 by P; wherein the sequences are as defined in the specification. Also disclosed is its use in treating cancer.
Patent NZ-614112-A (NZ)
Title: Media trading
Inventor: LANDSBERRY DAVID FREDERICK
IPC: H04N21/81
Filed: 2010-08-13
Abstract: A computer-implemented method and a media trading platform computer system for advertisement placement with a media owner are disclosed. , The media trading platform computer system (100) is operable to a) receive a booking request from a media buyer (120) to place an advertisement in a requested advertising slot, b) automatically interrogate a set of booking rules (144) specified by the media owner comprising one or more booking rules at an automated booking rules module and processing the received booking request to determine whether the received booking request satisfies the set of booking rules; c) if the received booking request satisfies the set of booking rules sending a booking request confirmation to the media buyer that the received booking request has been accepted; but, (d) if the received booking request does not satisfy the set of booking rules because the requested advertising slot is unavailable, then the media trading platform computer system determines whether an alternative advertising slot that satisfy the set of booking rules is available and, if an alternative advertising slot is available sends an offer offering the alternative advertising slot to the media buyer computer system
Patent NZ-619690-A (NZ)
Title: Method for measuring a height profile of a vehicle passing on a road
Inventor: CHRISTIAN JANNER
IPC: G01C3/20
Filed: 2014-01-08
Abstract: 619690 Disclosed is a method for measuring a height profile of a vehicle (2) passing on a road (1). A monocular camera(4) is directed from a point above the road (1) onto the road (2) with an angle of aperture that captures a section of the road (1) from above. At least a first image of the passing vehicle (2) is recorded by means of the camera (4) at a first moment in time (t1) and at least a second image of the passing vehicle (2) is recorded by means of the camera (4) at a second moment in time (t2). A movement vector image of the vehicle (2) is generated from an analysis of the optical flow between the first and the second image, and creating the height profile of the vehicle (2) is generated from the movement vector image.
Patent NZ-623006-A (NZ)
Title: Sensation-improving agent
Inventor: UEDA NORIKO
IPC: A23K10/28
Filed: 2012-10-02
Abstract: Disclosed is a sense-improving agent that is safe and has the effect of improving dulling of peripheral senses by routine consumption or application to the skin. Also disclosed is to provide a food and beverage product, feed, and cosmetic product for improving senses that have the effect of improving peripheral senses by oral ingestion or application to the skin. A sense-improving agent is provided that uses a milk-derived protein and/or milk-derived protein decomposition product which is one of actoperoxidase, lactoferrin, cystatin and angiogenin as the active ingredient. The milk-derived protein and/or milk-derived protein decomposition product is capable of improving dulling of the senses, particularly the peripheral senses, and can be used in a food and beverage product, feed, or cosmetic for improving the senses.
Patent NZ-626610-A (NZ)
Title: Antibodies that bind csf1r
Inventor: WONG JUSTIN
IPC: C12N5/10
Filed: 2011-05-04
Abstract: Disclosed is an antibody that binds to colony stimulating factor 1 receptor (CSF1R), comprising the CDRs of the sequences as disclosed in the specification. Also disclosed is its use in treatment.
Patent NZ-626949-A (NZ)
Title: Ion exchange membrane chromatography
Inventor: BILL JEROME JOSEPH JR
IPC: C07K16/00
Filed: 2012-12-18
Abstract: Methods of enhancing efficiency of downstream chromatography steps for purification of proteins comprising: (a) passing a composition comprising a polypeptide of interest and various contaminants through an ion exchange membrane, wherein the polypeptide and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH sufficiently distinct from the pI of the polypeptide to enhance the charge of the polypeptide and a low ionic strength effective to prevent the shielding of charges by buffer ions, which cause the membrane to bind the polypeptide and at least one contaminant, (b) overloading the ion exchange membrane such that at least one contaminant remains bound to the membrane while the polypeptide of interest is primarily in the effluent; (c) collecting the effluent from the ion exchange membrane comprising the polypeptide of interest; (d) subjecting the membrane effluent comprising the polypeptide of interest to a purification step of similar charge as the previous membrane, and (e) recovering the purified polypeptide from the effluent of the charged ion exchange chromatography purification step.
Patent NZ-700748-A (NZ)
Title: A pair of scissors
Inventor: SCHMIDT SARAH
IPC: B26B29/04
Filed: 2013-03-05
Abstract: A pair of scissors is disclosed. The scissors comprise a first and second blade which are arranged to pivot between an open configuration in which the first and second blades are angularly separated about a pivot disposed intermediate a proximal and distal end of the blades, to define a mouth for receiving material to be cut, and a closed configuration in which the first and second blades are substantially aligned to close the mouth. The scissors further comprising a constraint comprising a formation disposed on the first blade and a complementary slot disposed on the second blade. The constraint being arranged to limit the extent to which the first and second blades can pivot to the open configuration, to limit the opening of the mouth. Wherein, the constraint is further arranged to limit the extent to which the first and second blades can pivot to the closed configuration, thereby defining a maximally closed configuration in which the mouth is not fully closed.
Patent NZ-730054-A (NZ)
Title: Compositions and methods of use for treating metabolic disorders
Inventor: HALDANKAR RAJ
IPC: A61K39/00
Filed: 2015-10-29
Abstract: A complex comprising a GDF15 polypeptide is described. Methods of treating individuals with a metabolism disorder, such as, glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.