baber/WOPTO huggingface dataset:
Patent DE-60008917-T2 (DE)
Inventor: AOTSUKA TOMOJI
IPC: A61P13/12
Filed: 2000-12-07
Granted: 2005-03-10
Abstract: The purpose is to provide selective PDE IV inhibitors which have a potent anti-asthmatic profile with excellent safety. A compound of the formula (1): <CHEM>  wherein:   A is an unsubstituted or optionally substituted 5 or 6 membered heteroaryl group or a fused benzene ring in which any of the above-defined heteroaryl groups is fused to a benzene ring,   B is carbon or nitrogen, R<1> is hydrogen, lower alkyl, trifluoromethyl, hydroxyl, lower alkoxy, a residue derived from a carboxylic acid or a derivative thereof, amino, or an amino nitrogen-containing group, R<2> is hydrogen, halogen, cyano, nitro, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, trifluoromethyl, hydroxyl, lower alkoxy, a residue derived from a carboxylic acid or a derivative thereof, amino, or an amino nitrogen-containing group, and   m is an integer of from 1 to 8, both inclusive; or a pharmaceutically acceptable salt thereof possesses selective PDE IV inhibition and is useful as a pharmaceutical drug, preferably an anti-asthmatic, etc.
Patent DE-60011491-T2 (DE)
Inventor: WADSWORTH JOHN F
IPC: A61N1/05
Filed: 2000-03-02
Granted: 2005-08-18
Abstract: A deflectable catheter comprises a catheter body (12), a tip section (14) and a control handle (16). The control handle, which is preferably curved, comprises a housing (102) having a generally hollow interior, a piston receiving assembly (116) at least partially within the interior of the housing, and a piston. The piston receiving assembly is afforded rotational movement but not longitudinal movement relative to the housing and comprises a generally tubular member defining a piston chamber. The piston is fixedly attached to the proximal end of the catheter body and extends into the piston chamber of the piston receiving assembly, wherein the piston is afforded longitudinal movement but not rotational movement relative to the piston receiving assembly. Rotation of the piston relative to the housing correspondingly rotates the piston receiving assembly, catheter body and tip section. A puller wire extends from the control handle, through a lumen in the catheter body and into a lumen in the tip section. The proximal end of the puller wire is anchored in the control handle, whereby distal movement of the piston relative to the piston receiving assembly results in distal movement of the catheter body relative to the puller wire. The puller wire is anchored in the tip section so that to distal movement of the catheter body relative to the puller wire deflects the tip section (14). <IMAGE>
Patent DE-60012975-T2 (DE)
Inventor: SOEDERHOLM JAN
IPC: B65D33/20
Filed: 2000-11-20
Granted: 2005-08-11
Abstract: A closure device for packages having at least one self-adhesive closure element is disclosed. It comprises a self-adhesive glue layer (L<SUB>1</SUB>, L<SUB>2</SUB>) on the closure element, arranged for closing of the package. A release layer (F<SUB>1</SUB>, F<SUB>2</SUB>) covers the glue layer (L<SUB>1</SUB>, L<SUB>2</SUB>). At least one tear strip (G<SUB>1</SUB>, G<SUB>2</SUB>) is provided such that it can be torn through the package when the package is closed to form an opening. The tear strip (G<SUB>1</SUB>, G<SUB>2</SUB>) is provided on a part of the package forming the closure element, and on one side thereof that is facing inwards when the package is closed. Finally, the tear strip (G<SUB>1</SUB>, G<SUB>2</SUB>) is provided with a silicone layer on the side thereof facing the material of the package when the package is in a closed condition.
Patent DE-60015222-T2 (DE)
Inventor: NOMURA TAKESHI
IPC: C08G18/75
Filed: 2000-04-13
Granted: 2006-02-02
Abstract: A polyisocyanate prepolymer with isocyanate group on terminal obtainable by reaction of (A) polyoxyalkylenepolyol, (B) polyhydric alcohol having a molecular weight of 90 to 250 and the number of hydroxyl group of 2 to 3 with branched alkyl group and/or cyclohexane ring and (C) organic polyisocyanate composed of bis(isocyanatemethyl)cyclohexane, wherein NCO group content in the polyisocyanate prepolymer is 8 % by weight or above and urethane group content in the polyisocyanate prepolymer is 8 % by weight or above and sum total of NCO group content and urethane group content is 16 to 30 % by weight and a concentration of unreacted (C) organic polyisocyanate remained in the polyisocyanate prepolymer is 1 % by weight or below.
Patent DE-60016736-T2 (DE)
Inventor: DAVIES GERALD HOWARD
IPC: B05D3/10
Filed: 2000-03-17
Granted: 2006-01-05
Abstract: A process for primer coating of steel which is intended to be fabricated and overcoated, in which process the steel is primer coated with a primer coating comprising a silica or silicate binder, wherein the binder comprises an aqueous silica sol or alkali metal silicate having a SiO<SUB>2</SUB>/M<SUB>2</SUB>O mole ratio, where M represents total alkali metal and ammonium ions, of at least 6:1, and that after the primer coating has dried to the extent that it is touch dry it is treated with a solution which increases the film strength of the primer coating.
Patent DE-60022507-T2 (DE)
Inventor: MAZER B
IPC: A61K9/28
Filed: 2000-06-28
Granted: 2006-07-13
Abstract: Dosage form unit is provided to deliver one or more beneficial agents into a fluid, such as liquid enteral nutritional product. The dosage form unit includes a core containing at least one beneficial agent, preferably a marker dye, which is dispersible in the fluid. The core also contains a compatible binding agent to bind the beneficial agent together. Additional components of the core may include a plasticizer, a standard flow agent, a lubricant, additional tableting aids and at least one hydrophilic agent. A latex coating encases the core. The latex coating includes a mixture containing a substantially hydrophobic base material, preferably formed from an emulsion of cellulose acetate microspheres, which is capable of defining a matrix-type membrane, and at least one hydrophilic component being dispersible in the fluid. A dispersible beneficial agent is preferred as one of the hydrophilic components of the latex coating to allow immediate release of the beneficial agent therefrom. A method of making the dosage form unit also is provided.
Patent DE-60023707-T2 (DE)
Inventor: ANDERSON GREGOR JOHN MCLENNAN
IPC: A61P43/00
Filed: 2000-07-04
Granted: 2006-07-20
Abstract: A valve that includes a valve body, a valve stem having a dispensing passage, and a sealing ring that contacts the valve stem is described. The sealing ring includes a flexible component and a rigid component.
Patent DE-60026066-T2 (DE)
Inventor: VERMAAT PIETER
IPC: B23K37/053
Filed: 2000-11-01
Granted: 2006-11-02
Abstract: Method for welding pipes to each other, during which the outer side of the one pipe is engaged tightly with the help of first clamping means and the outer side of the other pipe is engaged tightly with the help of second clamping means, in which the first and second clamping means are kept in line and with their ends close to or against each other by means of a rigid frame on which both clamping means are arranged, wherein the shape of the one pipe is determined with the help of the first clamping means, said shape is stored in a memory as shape data, the second clamping means are brought into engagement with the other pipe and -based on the shape data stored in the memory- are urged into a position corresponding to the shape stored, after which welding means are operated in order to make a welding seam from the outside for connecting both pipes.
Patent DE-60028208-T2 (DE)
Inventor: GOBLET LAURENT
IPC: B68C1/02
Filed: 2000-10-13
Granted: 2007-05-03
Abstract: Saddle tree, especially for horse-riding, has a one-piece support with a pommel (14), cantle (15) and seat (16) made from composition materials selected for their ability to conform to the required shape, and conferring qualities of strength and suppleness, with fastenings (21) for auxiliary components. The support can be substantially solid and incorporate reinforcing elements or have thickened edges, and the fastenings can be in the form of holes, clamps, recesses, relief sections or inserts.
Patent DE-60030842-T2 (DE)
Inventor: GREER B
IPC: A61K41/00
Filed: 2000-03-01
Granted: 2007-05-10
Abstract: The present invention is related to agents useful in the treatment of tumors by radiation by sensitizing tumor cells toward the radiation. The agents of the invention can perform selective tumor radiosensitization and be involved in tumor directed hypomethylation. The agents of the invention include (a) 5-chloro-2'-deoxycytidine (CldC) administered without a cytidine deaminase inhibitor, (b) CldC administered with a cytidine deaminase inhibitor, (c) CldC and 4-N-methylamino 5-fluoro-2'-deoxycyxtidine (4-N-methylamino FdC), or (d) CldC and 4-N-methylamino FdC coadministered with a cytidine deaminase inhibitor. The cytidine deaminase inhibitor can be tetrahydrouridine or Zebularine. Within the scope of the invention are methods of treating tumors by administering the agents of the present invention without the need of other modulators of metabolism. Another aspect of the invention is a method of hypomethylating a gene silenced in a tumor of a subject by administering the agents of the invention to the subject to reduce the aggressiveness of the tumor, the metastatic propensity of the tumor, the genetic instability of the tumor, and/or the resistance of the tumor to drug or radiation treatment. An additional aspect of the invention is a method of protecting normal tissues during a radiation treatment of a tumor in a subject by administering the agents of the invention to the subject before or during the radiation treatment. The agents of the invention can be combined with new sources or new schedules of radiation, and new categories of tumors can also be treated with the agents of the invention.
Patent DE-60105500-T2 (DE)
Inventor: UEDA YUTAKA
IPC: B32B27/42
Filed: 2001-06-26
Granted: 2005-10-13
Abstract: In a honeycomb sandwich panel (11) having a honeycomb core (12), and a main surface layer (13) and a rear surface layer (14) sandwiching the honeycomb core on its upper and lower surfaces, at least one of the main surface layer (13) and the rear surface layer (14) is made of a fiber reinforced plastic using a phenolic resin as a matrix. <IMAGE>
Patent DE-60106210-T2 (DE)
Inventor: WALKER P
IPC: B26B21/40
Filed: 2001-02-27
Granted: 2005-10-13
Abstract: A shaving razor blade unit that has a plurality of blades and a guard that includes two groups of rows of elongated, elastomeric fins arranged generally parallel to the cutting edges of the blades. The first group of fins has tips with increasing elevation with respect to a plane passing through the cutting edges, and the second group of fins has tips of generally uniform position relative to the plane. Also disclosed are a guard with at least six rows of elongated, elastomeric fins arranged generally parallel to the cutting edges of the blades; a guard that includes at least five rows of elongated, elastomeric fins that are arranged generally parallel to the cutting edges of the blades and generally increase in elevation with respect to a plane passing through the cutting edges of the blades in going from fins further from the blades to fins closer to the blades; and fins that converge from a base portion to a tip portion at an included angle of less than 14 degrees.
Patent DE-60107309-T2 (DE)
Inventor: RIJ HANS VAN
IPC: F24D3/14
Filed: 2001-03-14
Granted: 2005-12-08
Abstract: System for fixing hoses, tubes or other conduits or elongated elements on a foundation onto which still a layer of material has to be applied, which system comprises a number of elements which in the operational situation extend over a predetermined distance upwards, which elements are made of a material which is shaped into strips and which elements comprise openings or excavations which in the operational situation will receive a part of a hose, tube, conduit or other elongated element and will fix said part approximately parallel to the foundation, whereby the thickness of the strips is increased around the edges of said openings or excavations. <IMAGE>   <IMAGE>   <IMAGE>   <IMAGE>
Patent DE-60110749-T2 (DE)
Inventor: BOLD GUIDO
IPC: A61K31/47
Filed: 2001-02-07
Granted: 2006-02-02
Abstract: The invention relates to pyridine derivatives of formula (I) wherein the substituents and symbols are defined as indicated in the description, processes for the preparation thereof, their usage in the preparation of a pharmaceutical composition for the treatment of a disease which responds to an inhibition of angiogenesis, and pharmaceutical compositions containing such compounds.
Patent DE-60112637-T2 (DE)
Inventor: KITA NOBUYUKI
IPC: G03F7/11
Filed: 2001-03-19
Granted: 2006-06-14
Abstract: A heat-sensitive lithographic printing plate precursor is disclosed, comprising a metal substrate having thereon 1) an ink-receptive layer, 2) a water-receptive layer comprising a colloidal particulate oxide or hydroxide of at least one element selected from the group consisting of beryllium, magnesium, aluminum, silicon, titanium, boron, germanium, tin, zirconium, iron, vanadium, antimony and transition metals, or additionally 3) a water-soluble overcoat layer, at least one layer of the ink-receptive layer, the water-receptive layer and the overcoat layer containing a compound capable of converting light into heat and the ink-receptive layer containing an epoxy resin having a softening point of 120 DEG C or more.
Patent DE-60115440-T2 (DE)
Inventor: DAVENPORT CHRISTOPHER JOHN
IPC: B21B1/36
Filed: 2001-06-22
Granted: 2006-08-03
Abstract: A method of reducing the thickness of metal sheet by cold rolling the metal sheet at least once using work rolls, whereby at least one of the work rolls has an effective Young's Modulus less than that of steel. A work roll for use in this method having an effective Young's Modulus less than that of steel. <IMAGE>
Patent DE-60117936-T2 (DE)
Inventor: TETU LEE G
IPC: F04D29/28
Filed: 2001-08-29
Granted: 2006-08-17
Abstract: A fan blade configuration for a radial fan includes support structure (28) for the cantilevered portion of each blade (14). This support structure is preferably affixed to an upper circumferential ring (10) of the radial fan and extends outwardly therefrom in support of the cantilevered portion of the blade (14). The support structure (28) preferably extends along the cantilevered portion of the blade (14) for a predefined distance. The distance is preferably expressed relative to a distance to a point (15) at which the leading edge of the blade (14) terminates. The predefined distance is also a function of the downward inclination of the support structure (28) extending along the cantilevered portion. The support structure (28) extends underneath the outer ring (10) so as to define an aligning surface for the rearward portion of the respective fan blade (14). <IMAGE>
Patent DE-60120188-T2 (DE)
Inventor: GUSTAVSSON MATS
IPC: F25D16/00
Filed: 2001-09-05
Granted: 2007-03-29
Abstract: A system for controlling the cooling of small milk quantities in a cooling tank (4). An agitation pipe (2) extended through a regular milk outlet (26) in a first end wall (6) of the tank is provided, having a nozzle end (32) for introducing incoming/re-circulated milk onto a milk cooling surface (14) at a predetermined position (dp). The position (dp) being situated (1) between a first end wall (6) and a central part of the tank (4) and laterally displaced (b) relative to the perpendicular central axis of the tank. The nozzle end (32) is directed towards a second end wall (8) of the tank (4). Agitation is performed by the agitation pipe (2) upon demand or when the milk quantity is insufficient for a regular agitator element (27) to work properly.
Patent DE-60121204-T2 (DE)
Inventor: VENETJOKI PETTERI
IPC: B65H63/00
Filed: 2001-10-11
Granted: 2007-05-31
Abstract: The invention relates to a safety device (SD) to be used in connection with machines and devices in the production or finishing line of paper and/or paperboard as well as in connection with devices utilized for production of pulp used in the manufacture of paper and/or paperboard. According to the invention the safety device (SD) comprises a reeling core (RC) and a safety structure (SW) reeled around said reeling core (RC). In a preferred embodiment of the invention the reelable safety device (SD) is composed of separate, substantially rigid lamellae (L) that are attached to each other in an articulated manner. As a result of the reelable structure, the safety device (SD) can be easily reeled away from the working area during maintenance and repair and thereafter it can be easily and rapidly reeled back into its place. The safety device (SD) according to the invention enables protection against various factors that reduce occupational safety and impair working conditions, such as mechanical hazards, heat and noise.
Patent DE-60122343-T2 (DE)
Inventor: CHUA L
IPC: H05K7/02
Filed: 2001-05-10
Granted: 2006-12-14
Abstract: An out-of-plane micro-structure which can be used for on-chip integration of high-Q inductors and transformers places the magnetic field direction parallel to the substrate (14) plane without requiring high aspect ratio processing. The photolithographically patterned coil structure includes an elastic member (61 a) having an intrinsic stress profile. The intrinsic stress profile biases a free portion (11) away from the substrate (14) forming a loop winding (142). An anchor portion (12) remains fixed to the substrate (14). The free portion end becomes a second anchor portion (61 c) which may be connected to the substrate (14) via soldering or plating. A series of individual coil structures (140) can be joined via their anchor portions to form inductors and transformers.
Patent DE-60123439-T2 (DE)
Inventor: TOMKINS PHILIP
IPC: B65D90/00
Filed: 2001-08-17
Granted: 2007-08-23
Abstract: Frames and attachments thereto and methods of use thereof for the support and/or releasable securing of cargo and/or cargo containers upon and/or to cargo containers and/or cargo container transports and/or lifting devices. Linking frame (10) may be used upon and/or beneath containers that possess insufficient mutually corresponding mounting-points to otherwise enable them to be vertically stacked and secured together. Parallel longitudinal beams (11) are joined by shorter lateral beams (12). Attached directly or indirectly, protruding outward the outer side surfaces of said framework, are connectors (13) able to correspond upwardly and/or downwardly with various mounting-point layouts as provided upon the surfaces of cargo transport equipment.
Patent DE-60127087-T2 (DE)
Inventor: POWERS JEFFRY E
IPC: G01S15/89
Filed: 2001-08-23
Granted: 2007-12-13
Abstract: An ultrasonic imaging method and apparatus are described for imaging a volumetric region using a two dimensional array transducer. The ultrasonic probe includes the 2D array transducer and microbeamformers for beamforming signals from groups of elements of the array in the probe. The microbeamformers are capable of dynamically steering or focusing the beams received by a group or "patch" of elements. The beamformed patch signals are coupled to the beamformer in the ultrasound system where the final stage of beamforming is performed.
Patent DE-60133448-T2 (DE)
Inventor: AHN YOUNG-JOON
IPC: A01N65/08
Filed: 2001-02-05
Granted: 2009-05-07
Abstract: The present invention relates to an acaricidal composition isolated from plants, and more particularly, to an acaricidal composition comprising one and more compounds selected from a group consisting of Paeonia suffruticosa, Cnidium officinale, Cinnamomum cassia, cinnamon, mustard and horseradish. Also, the present invention provides an acaricidal composition of one or more compounds selected from a group consisting of trans-cinnamaldehyde, cinamyl alcohol, salicylaldehyde, allyl isothiocyanate and butyl isothiocyanate. When trans-cinnamaldehyde, cinamyl alcohol and salicylaldehydehave are blended, they have a synergic effect. <IMAGE>
Patent DE-60201148-T2 (DE)
Inventor: BERTUZZI IVANOE
IPC: B65G47/57
Filed: 2002-05-29
Granted: 2005-09-22
Abstract: A conveyor (1), for feeding articles (2) along a given path (P1) and in a vertical direction (D1), has a guide (8) parallel to the aforementioned direction (D1) and having a succession of first supports (17) defining a succession of first seats (25), each for housing an article (2); and a slide (9) movable back and forth in the aforementioned direction (D1) and having a succession of second supports (17a) defining a succession of second seats (28), each for housing an article (2) and for transferring an article (2) between two adjacent first seats (25). <IMAGE>
Patent DE-60202203-T2 (DE)
Inventor: CHEEMA LAL
IPC: C07D498/08
Filed: 2002-04-12
Granted: 2005-12-15
Abstract: There is provided a process for the preparation of a compound of formula (I): which process comprises reaction of a compound of formula (TI): with either a compound of formula (ITT): or acrylamide, followed, in the latter case, by reaction of the resulting intermediate of formula (IV): with an alcohol of formula R<SUP>2</SUP>-OH and an agent that promotes, or agents that in combination promote, rearrangement and oxidation of the compound of formula IV to an intermediate isocyanate, which may then react with the alcohol of formula R<SUP>2</SUP>-OH, and wherein R<SUP>1</SUP>, R<SUP>2 </SUP>and R<SUP>16 </SUP>have meanings given in the description.
Patent DE-60219005-T2 (DE)
Inventor: CORVARI VINCENT
IPC: A61K9/16
Filed: 2002-05-23
Granted: 2007-12-13
Abstract: The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
Patent DE-60219439-T2 (DE)
Inventor: WILLETT WILLIAM
IPC: A63H3/36
Filed: 2002-02-12
Granted: 2007-12-13
Abstract: A tiny articulation eye and mouth (facial-expression structures) opening and closing structure installable in the hollow interior of a doll head, and utilizing a single, upright-axis motor, and a rotary, co-axial, stepped-diameter drive drum which is rotated by the motor. Circumferential drive tracks formed on the outside of the drum drive followers and actuation which directly impart opening and closing motions in the doll head's eyes and mouth.
Patent DE-60226108-T2 (DE)
Inventor: CHASSE CARL A
IPC: B65D85/24
Filed: 2002-09-11
Granted: 2009-05-28
Abstract: A package (10) for a plurality of products, having a closed container having a container wall (16), the wall defining a cavity for holding the products, and the wall having a product holder adapted to hold at least one selected product in a position visible from outside the container. The holder is an inwardly and/or outwardly opening recess (50,60) formed in the wall, and the at least one selected product (51,61) is positioned in the recess. The holder includes an outer member restraining the selected product to the outwardly opening recess, such as a packaging label (40), having a transparent portion forming a viewing window (42,43) for viewing the selected product. In yet another aspect, the plurality of products in the cavity may be identical primary products, such as screws. The selected product may be different from the primary product, such as a driver bit for driving the screws. <IMAGE>