baber/WOPTO huggingface dataset:
Patent CA-3092512-A1 (CA)
Title: Dispositif permettant d'effectuer des mesures electriques
Inventor: VULTO PAUL
IPC: B01L3/00
Filed: 2019-03-01
Abstract: L'invention concerne un dispositif permettant d'effectuer des mesures électriques, par exemple une activité électrique à travers une couche de cellules épithéliales. Le dispositif comprend une cassette ayant des première et seconde surfaces, la cassette étant configurée pour venir en prise avec une plaque de microtitration et comprenant une pluralité d'électrodes s'étendant à partir de la première surface dans la direction de la plaque de microtitration lorsque la cassette est en prise avec la plaque de microtitration ; et un boîtier fixé de manière amovible à la seconde surface de la cassette, comprenant un ou plusieurs éléments de gestion thermique, et un processeur comprenant un module d'acquisition de données connecté électriquement aux électrodes et un module de traitement de données. L'invention concerne également un procédé de mesure vitro de propriétés électriques de cellules cultivées dans un dispositif microfluidique, par exemple à l'aide du dispositif.
Patent CA-3095788-A1 (CA)
Inventor: KWON GLEN S
IPC: A61K47/59
Filed: 2019-04-01
Abstract: The present technology relates generally to oligolactic acid conjugates and stereocomplexes of conjugates of gemcitabine and gemcitabine derivatives, micelle compositions containing such conjugates or stereocomplexes of conjugates, and methods of preparing and using such compositions to treat various cancers. The oligolactic acid conjugates and stereocomplexes of conjugates may include oligolactic acid comprising 2 to 20 lactic acid subunits and may be attached through an amide linkage to the nitrogen of the 4(N) of the gemcitabine or gemcitabine derivative. Compositions comprising water and a micelle comprising a polylactic acid-containing polymer and the oligolactic acid conjugate or stereocomplex of conjugates may be readily prepared. Methods of inhibiting or killing cancer cells and treating gemcitabine sensitive cancers are also provided.
Patent CA-3097216-A1 (CA)
Title: Procede de communication sans fil destine a un spectre sans licence, et dispositif
Inventor: WU ZUOMIN
IPC: H04W16/14
Filed: 2019-01-18
Abstract: Selon des modes de réalisation, la présente invention concerne un procédé de communication sans fil destiné à un spectre sans licence, et un dispositif, apte à améliorer la flexibilité de communication en termes de communications de spectre sans licence. Le procédé consiste : à envoyer, par le biais d'un premier dispositif terminal, de premières informations d'indication à un dispositif de réseau par l'intermédiaire d'une première opportunité de transmission dans un temps d'occupation de canal (COT) obtenu par le premier dispositif terminal, le COT comprenant une deuxième opportunité de transmission et une troisième opportunité de transmission, et les premières informations d'indication étant utilisées afin de déterminer la deuxième opportunité de transmission dans le COT par le dispositif de réseau.
Patent CA-3097902-A1 (CA)
Title: Modification of glutamine synthetase to improve yield in plants
Inventor: BASS STEVEN HENRY
IPC: C07H21/04
Filed: 2019-05-20
Abstract: Provided are compositions comprising polynucleotides encoding glutamine synthetase (GS) polypeptides having improved properties, such as increased enzymatic activity and/or increased thermostability. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides. Additionally, various methods of employing the polynucleotides in plants, such as methods for increasing GS activity in a plant, methods for increase seed protein content in a seed of a plant, and methods for increasing yield of a plant, are also provided herein.
Patent CA-3097921-A1 (CA)
Inventor: KLOIBER-MAITZ MONIKA
IPC: C12Q1/68
Filed: 2019-04-24
Abstract: The present invention relates to plants, such as maize, sorghum or sugar cane, having improved digestibility, in particular improved stover digestibility. The present invention relates to a QTL allele associated with improved digestibility and specific marker alleles associated with the QTL allele. The present invention further relates to such plants, wherein the F35H gene is mutated or wherein F35H expression is altered. The invention also relates to methods for identifying plants having improved digestibility and methods for obtaining such plants.
Patent CA-3100208-A1 (CA)
Title: Method for extracting soluble si from an amorphous sio2 bearing material
Inventor: CROOKS REGAN
IPC: C09K17/12
Filed: 2019-05-24
Abstract: The present invention relates to bioavailable (which may also be referred to as plant available) silicon, such as in the form of a concentrate or solid, and processes for producing and using bioavailable silicon.
Patent CA-3103641-A1 (CA)
Inventor: LIMBACH KIRK W
IPC: B01J37/02
Filed: 2019-06-20
Abstract: A heterogeneous catalyst comprising a support and gold, wherein: (i) said support comprises titanium, (ii) said catalyst comprises from 0.1 to 5 wt% of gold, (iii) at least 90 wt% of the gold is in the outer 60% of catalyst volume, and (iv) particles of the catalyst have an average diameter from 200 microns to 30 mm; wherein weight percentages are based on weight of the catalyst. The catalyst of this invention is useful in a process for producing methyl methacrylate (MMA) which comprises treating methacrolein with methanol in an oxidative esterification reactor (OER) containing a catalyst bed.
Patent CA-3105251-A1 (CA)
Title: Crystalline salts of 5-methyl-(6s)-tetrahydrofolic acid and amino acid ethyl esters
Inventor: MOSER RUDOLF
IPC: A61P19/10
Filed: 2019-07-02
Abstract: The present invention refers to a crystalline salt comprising 5-methyl-(6S)-tetrahydrofolic acid and an amino acid ethyl ester like L-phenylalanine ethyl ester or L-methionine ethylester, wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to amino acid ethyl ester is from 1:0.3 to 1:3.0 (in mol/mol) and/or hydrates and/or solvates thereof as well as to a process of obtaining the same.
Patent CA-3114323-A1 (CA)
Inventor: HORNACEK MICHAEL
IPC: G01M3/18
Filed: 2019-09-24
Abstract: The invention relates to identifying the occurrence of a defect (11) in a pipeline (10) by means of estimation, wherein at least one first indicator (40) is identified by a first detection means (20) assigned to a first detection location (30), from which indicator a first estimation value regarding the occurrence of the defect (11) in the pipeline (10) is determined by means of a first estimation function, and at least one second indicator (41-43) is identified by at least one second detection means (21-23) assigned to a second detection location (31-33), from which indicator at least one second estimation value regarding the occurrence of the defect (11) in the pipeline (10) is determined by means of at least one second estimation function, and an overall estimation value is determined from the first estimation value and the at least one second estimation value by means of an overall estimation function by taking into account the respective positions of the first detection location (30) and of the second detection location (31-33), from which overall estimation value the occurrence of the defect (11) is estimated.
Patent CA-3115551-A1 (CA)
Inventor: BOWEN DAVID J
IPC: C07K14/325
Filed: 2020-01-21
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3 pesticidal proteins are also provided. Also disclosed are methods and compositions to improve the insecticidal activity of a pesticidal protein against an insect pest species. Further disclosed are method and compositions to reduce expression of a pesticidal protein in the reproductive tissues of a transgenic plant.
Patent CA-3115838-A1 (CA)
Title: Systems and methods for automated article transportation and management thereof
Inventor: BIDRAM FARHANG
IPC: G06Q50/02
Filed: 2019-10-09
Abstract: A system for managing and tracking plant management at a site is provided that includes a device management server communicatively connected to a plant management device. The plant management device is configured to: receive a plant management task order including task instructions for performing a plant management task and automatically perform the plant management task according to the task instructions; send a task receipt notification including task beneficiary data to the device management server; and transmit task performance data that is logged during performance of the plant management task to the device management server. The device management server is configured to: generate a work report for the plant management device from the task performance data; generate a billing report including a billable amount for the plant management device from the task beneficiary data and billing rate data; and generate a productivity profile for the plant management device.
Patent CA-3118956-A1 (CA)
Inventor: HANAFIALAMDARI HAMED
IPC: A61B5/08
Filed: 2019-11-11
Abstract: Selon divers modes de réalisation, la présente invention concerne un dispositif de commande destiné à commander le fonctionnement d'un dispositif d'assistance respiratoire qui fournit une assistance respiratoire à un utilisateur. Le dispositif de commande comprend un processeur qui génère une valeur d'indice respiratoire qui est déterminée pendant une période de temps de surveillance actuelle pour détecter une insuffisance respiratoire, ou prédire l'insuffisance respiratoire lorsqu'au moins un signal PSG est mesuré. La valeur d'indice respiratoire est comparée à un seuil pour déterminer si le signal de commande doit être mis à jour pour réduire ou éliminer une insuffisance respiratoire que l'utilisateur subit actuellement ou pour empêcher la survenance d'une insuffisance respiratoire qui a été prédite.
Patent CA-3119588-A1 (CA)
Title: Seat belt fixing device and seat comprising the same
Inventor: XIAO XIAOHONG
IPC: B60N2/28
Filed: 2021-05-25
Abstract: A seat belt fixing device and a seat including the same are introduced. The seat belt fixing device includes a seat belt clamp, top rod body, fixedly engaging element, locking element, and operating element coupled to the locking element. The seat belt clamp includes a first clamping element rotatably mounted on the seat and a second clamping element formed on the seat. The second clamping element is rotatable to a locked position to operate in conjunction with the first clamping element in clamping a seat belt. The top rod body and the second clamping element are connected and rotate concentrically. The locking element and fixedly engaging element are mounted on the top rod body (or second clamping element) and the seat, respectively. At the locked position, the locking element fittingly, engagingly connects to the fixedly engaging element to lock the top rod body and second clamping element.
Patent CA-3120154-A1 (CA)
Title: Fault detection technique for a bearing
Inventor: KENNY SHAWN A
IPC: F16C41/00
Filed: 2021-05-14
Abstract: Systems and methods are provided for fault detection in a component of a machine during operation. Vibration data is acquired based on a vibration signal output from a sensor associated with the component. The vibration data is analyzed with at least two machine learning models to predict a condition of the component.
Patent CA-3122205-A1 (CA)
Title: Methods for increasing fat oxidation or energy expenditure or satiety in an animal
Inventor: PAN YUANLONG
IPC: A23K10/00
Filed: 2019-12-06
Abstract: The present disclosure provides compositions and methods for increasing fat oxidation or energy expenditure or satiety in an animal comprising administering a non-ketogenic composition to the animal, wherein the non-ketogenic composition comprises about 5% to about 25% carbohydrates, about 30% to about 60% protein, and about 10% to about 40% fat. Additionally, the composition can have a protein to carbohydrate ratio of at least 2:1.
Patent CA-3125321-A1 (CA)
Title: (2,5-dioxopyrrolidin-1-yl)(phenyl)-acetamide derivatives and their use in the treatment of neurological diseases
Inventor: KAMINSKI KRZYSZTOF
IPC: A61K31/4465
Filed: 2020-01-07
Abstract: The first object of the invention is the compound of general formula (I) or pharmaceutically acceptable salts thereof. A second object of the invention is the use of compounds described by general formula (I) as active ingredient in pharmaceutical compositions for the treatment of epileptic seizures or neuropathic pain or migraine.
Patent CA-3126534-A1 (CA)
Inventor: BARADE GIRISH
IPC: B60T7/20
Filed: 2021-07-28
Abstract: A parking brake apparatus is provided for a power unit having air brake parking components and to which a towed unit having air brake parking components can be connected. The parking brake apparatus comprises a controller arranged to monitor a pressure signal indicative of a delivery air pressure applied to the air brake parking components of the towed unit when the towed unit is connected to the power unit. The controller is also arranged to provide a status signal indicative of whether or not a towed unit is connected to the power unit based upon the pressure signal. The controller further enables the status signal to be processed to control application or release of any combination of air brake parking components of the power unit and the towed unit to park or unpark the power unit as well as the towed unit, if connected to the power unit.
Patent CA-3129018-A1 (CA)
Title: Synthesis of functionalised polymers through devulcanisation from waste containing elastomers
Inventor: DEZ ISABELLE
IPC: C08J11/10
Filed: 2020-02-18
Abstract: The invention relates to a method for synthesising polymers through devulcanisation from waste containing elastomers, said method comprising: - a) contacting said waste containing elastomers with a solvent in the presence of a devulcanisation agent, - b) heating the mixture produced in step a), at a temperature of between 20°C and 250°C for a period of between 15 minutes and 24 hours in the presence of a devulcanisation agent, the concentration of devulcanisation agent being such that the ratio between said concentration of devulcanisation agent, expressed as parts per hundred of elastomer (phr) and a volume of solvent, expressed in ml, is: - greater than 0.3 phr/ml of solvent or less than 0.2 phr/ml of solvent when the method is carried out in air, - greater than 0.06 phr/ml of solvent when the method is carried out in an inert atmosphere.
Patent CA-3130287-A1 (CA)
Title: Flanged brake shoe
Inventor: BOWDEN A GARY
IPC: B61H1/00
Filed: 2020-02-26
Abstract: A brake shoe includes a backing plate configured to interface with a brake head of a vehicle. The backing plate includes a main body and a flange attached to the main body and configured to align the brake shoe on a wheel of the vehicle. The brake shoe also includes a composition friction material disposed on the backing plate, which defines a brake surface for engaging the wheel. The brake shoe may have one or more dimensional characteristics for facilitating alignment of the brake shoe with the wheel, e.g., a ratio of a shortest horizontal distance to a shortest vertical distance of the brake shoe may be at least 1.07 and no more than 1.25, or a ratio of a length of the main body of the brake shoe to a length of the flange may be at least 1.3 and not more than 1.7.
Patent CA-3133101-A1 (CA)
Title: Procedes et compositions therapeutiques pour traiter un lymphome a l'aide d'acide 6,8-bis-benzylthio-octanoique
Inventor: PARDEE TIMOTHY S
IPC: A61P35/00
Filed: 2020-03-19
Abstract: La présente invention concerne des procédés, des compositions et des kits médicaux pour traiter un lymphome à l'aide d'acide 6,8-bis-benzylthio-octanoïque (CPI-613, dévimistat) ou un sel pharmaceutiquement acceptable de celui-ci, éventuellement en combinaison avec un second agent thérapeutique (de préférence le chlorhydrate de bendamustine). Des formes préférées de lymphome traitées comprennent un lymphome de Burkitt récidivant ou réfractaire, un lymphome à cellules B, un lymphome de Hodgkin classique récidivant ou réfractaire, et un lymphome non hodgkinien à cellules T récidivant ou réfractaire.
Patent CA-3135461-A1 (CA)
Title: Warning system for roadside operations
Inventor: OLSON BRIAN R
IPC: E01F9/615
Filed: 2021-10-20
Abstract: A warning system for a work vehicle includes an arm mount attached to a side portion of the work vehicle above a head of a person standing on a ground surface adjacent to the side portion of the work vehicle, and an arm attached to the arm mount. The arm is movable from an arm transport position, where the arm is oriented inside a path of the work vehicle, to an arm operating position, where the arm extends laterally outward from the side portion of the work vehicle. A warning light is mounted on the arm and is visible to traffic approaching the work vehicle from a rear end of the work vehicle, and a work light on the arm shines downward on the operator to illuminate the person the oncoming traffic and to facilitate operation of controls.
Patent CA-3135535-A1 (CA)
Inventor: BAUER GUNTER
IPC: A61K8/73
Filed: 2020-03-30
Abstract: The present invention relates to liquid compositions as well as the use of liquid compositions for differentially promoting the growth of the microbiome. The liquid composition forms a membrane of the invention when applied to the skin of a subject. The liquid composition as well as the membrane comprise chitosan or a salt thereof with a degree of acetylation of 20 % or less and at least one further agent. The present invention further relates to pharmaceutical compositions for the treatment of dysbiosis.
Patent CA-3136011-A1 (CA)
Inventor: NI XIAOHUI
IPC: C12Q1/68
Filed: 2020-04-28
Abstract: The present disclosure provides methods and compositions for preparation of a nucleic acid library. In some embodiments, the nucleic acids comprise cell-free DNA, including cfDNA that is in need of analysis, such as by sequencing. The methods may comprise restriction enzyme digestion, adapter ligation, and subsequent amplification, and may provide improved approaches for reducing the number adapter dimers produced during the process. In an aspect, a method for preparing a library of nucleic acids may comprise: digesting DNA molecules with restriction enzymes to produce DNA fragments; ligating adapters to the DNA fragments by incubating with ligase to produce a mixture of adapter-ligated DNA fragments and adapter dimers; amplifying the adapter-ligated DNA fragments to produce amplified adapter-ligated DNA fragments; and reducing the quantity of the adapter dimers by differentiating between the junction between an adapter and a DNA fragment, and the junction between an adapter and another adapter.
Patent CA-3136530-A1 (CA)
Title: Cyclone separator and methods of using same
Inventor: BAAREN SANDER
IPC: B04C5/06
Filed: 2020-03-26
Abstract: One illustrative cyclone separator (10) disclosed herein includes an outer body (26), an inner body (72) positioned at least partially within the outer body, an internal flow path within the inner body (72), the internal flow path having a fluid entrance and a fluid outlet (70A), a first fluid flow channel between the inner body (72) and the outer body (26), and a re-entrant fluid opening (78) that extends through the outer body (26) and is in fluid communication with the fluid flow channel, wherein the re-entrant fluid opening (78) is positioned at a location upstream of the fluid entrance of the internal flow path in the inner body (72).
Patent CA-3136682-A1 (CA)
Inventor: O'CONNOR PAUL
IPC: C08B15/02
Filed: 2020-04-17
Abstract: The invention relates to a method for the preparation of micro- or nano crystalline cellulosic compositions from virgin cellulose using an aqueous solution comprising 40 - 65 wt.% ZnCl2 in water to preferentially dissolve the amorphous cellulosic phase and separating the dissolved amorphous cellulose to obtain micro- or nanocellulose having XRD type I structure and optionally contacting with a second solvent comprising between 65 and 90 wt.% ZnCl2 in water to produce delaminated cellulose having XRD type II structure. The invention also relates to micro- or nano crystalline cellulose type I or II having high crystallinity and purity and the uses thereof.
Patent CA-3137751-A1 (CA)
Title: A system for obtaining a photopolymerized prepolymer
Inventor: INDYK DENIS
IPC: C08F290/06
Filed: 2020-04-29
Abstract: A system for obtaining a photopolymerized prepolymer for use as a component of a material suitable for manufacturing buildings or building components by 3D printing processes. The system contains a flexible closed loop conveyor stretched between a precursor loading station and a prepolymerization material receiver from which the product is unloaded to a construction 3D printing machine. The conveyor carries a plurality of flexible trays capable of looping around the pulleys of the closed loop conveyor. The trays are shallow troughs that have open tops and carry dosed portions of the precursor, which is photopolymerized on its way from the loading station to the unloading station by sequentially passing under light sources of two photopolymerization stations. When the trays pass through the unloading position, they are turned upside-down and allow the precured material to fall into a receiver.
Patent CA-3139035-A1 (CA)
Inventor: BENNETT GAVIN
IPC: A61K31/337
Filed: 2020-05-11
Abstract: La présente invention concerne un procédé de traitement d'un cancer chez un patient.
Patent CA-3139285-A1 (CA)
Inventor: ZHOU XINGLU
IPC: A61K31/519
Filed: 2020-06-23
Abstract: Disclosed in the present invention is a novel substituted pyrazolopyrimidine compound that inhibits the activity of casein kinase 1? (CK1?) and a stereoisomer or stereoisomer mixture thereof, or a pharmaceutically acceptable salt or solvate thereof, and an application thereof in preparation of drugs for treating diseases, disorders or conditions that benefit from the inhibition of the activity of the casein kinase 1? (CK1?). The compound of the present invention has an inhibitory activity on CK1? kinase, OCI-LY10 cells and Karpas299 cells, shows good anti-tumor activity in an OCI-LY10 subcutaneous xenogeneic model and shows excellent synergistic anti-tumor activity in combination with BTK inhibitors. The compound of the present invention has good pharmacokinetics properties and may be used alone or in combination with other drugs to treat diseases, disorders or conditions that benefit from the inhibition of the activity of the casein kinase 1?, the diseases, disorders or conditions comprising tumors, autoimmune diseases, etc.
Patent CA-3141834-A1 (CA)
Inventor: PETTER LINDA MARIE
IPC: C12Q1/04
Filed: 2020-05-27
Abstract: Dans divers modes de réalisation, la présente invention concerne des testeurs pour détecter une infection bactérienne ainsi que des procédés de production et des utilisations de ceux-ci.