baber/WOPTO huggingface dataset:
Patent DE-60233942-D1 (DE)
Inventor: SCHOLZ CHRISTIAN
IPC: C12N5/071
Filed: 2002-06-24
Granted: 2009-11-19
Abstract: The present invention relates to the diagnosis of HIV infections. It especially teaches the production of a soluble retroviral surface glycoprotein- (or transmembrane glycoprotein)-chaperone complex and the advantageous use of a chaperone-antigen complex especially in the detection of antibodies to HIV in immunoassays, preferably according to the double antigen bridge concept, or as an immunogen. The invention also discloses soluble complexes comprising a variant of HIV-1 gp41 or a variant of HIV-2 gp36, respectively, and a chaperone selected from the peptidyl-prolyl-isomerase class of chaperones. Variants comprising specific amino-acid substitutions in the N-helical domain of HIV-1 gp41 or of HIV-2 gp36, respectively, arc also described.
Patent DE-60234189-D1 (DE)
Title: Selbst-formbare annuloplastie-ringprothese
Inventor: MARQUEZ SALVADOR
IPC: A61F2/24
Filed: 2002-08-20
Granted: 2009-12-10
Abstract: The resilient self-molding annuloplasty ring which may be enlarged prior to implantation to facilitate implantation with a dilated or otherwise incompetent valve annulus having sufficient contractive force to render a valve competent. The self-molding annuloplasty ring of the invention may further comprise integral attachment devices to aid in the implantation process. The invention further discloses an illustrative method of implantation.
Patent DE-60234225-D1 (DE)
Inventor: ALLEN JEFFREY
IPC: F01L9/10
Filed: 2002-04-19
Granted: 2009-12-10
Abstract: A method of operating a four stroke internal combustion engine comprising the steps of using inlet valve means (15) to regulate admission of a mixture of fuel and air into a combustion chamber (12), using a compressor (151) to compress the fuel and air mixture prior to admission of the mixture into the combustion chamber (12), using exhaust valve means (16) to regulate flow of combusted gases from the combustion chamber (12), closing the exhaust valve means (16) prior to the end of the exhaust stroke to trap combusted gases in the combustion chamber (12), opening the inlet valve means (15) during the intake stroke to admit a charge of fuel and air mixture into the combustion chamber (12) to be mixed with the previously trapped combusted gases, whereby in the combustion chamber (12) conditions are generated which enable the mixture of fuel, air and combusted gases to combust by auto-ignition, with the combusted gases expanding during the power stroke. 
By opening the inlet valve means (15) to admit a preconditioning charge of fuel and air into the combustion chamber (12) to be mixed with the trapped combusted gases after closing of the exhaust valve means (16) during the exhaust stroke and prior to the opening of the inlet valve means (15) in the induction stroke to admit the charge of fuel and air which is combusted to expand in the power stroke.
Patent DE-60235392-D1 (DE)
Inventor: FRAISSE EMMANUEL
IPC: G01F23/30
Filed: 2002-10-23
Granted: 2010-04-01
Abstract: A tank intended for an electrohydraulic braking system comprises, according to the present invention, a first chamber ( 7 ) for the supply of a primary hydraulic circuit of a master cylinder with brake fluid, a second chamber ( 9 ) for the supply of a secondary hydraulic circuit of the master cylinder (not shown) with brake fluid, a third chamber ( 11 ) for the supply of a hydraulic pump with brake fluid, and a fourth chamber ( 13 ), a measuring one, which accommodates a detection device, indicating when the brake-fluid level inside the tank is too low. The tank has a flow path for the interconnection of the first chamber ( 7 ), the second chamber ( 9 ) and the third chamber ( 11 ) when the hydraulic-fluid level is higher than a safety level, and for the fluid-tight separation of said chambers when the hydraulic-fluid level is lower than the safety level.
Patent DE-60235775-D1 (DE)
Inventor: DHONT MARIA
IPC: A61F2/04
Filed: 2002-11-08
Granted: 2010-05-06
Abstract: The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device, it is provided with at least one coating. The coating contains a therapeutic agent which is comprised in a matrix that sticks to the intraluminal device. Instead of being formed by a little bio-compatible polymer, the matrix is formed by a bio-compatible oil or fat, such as cod-liver oil or olive oil. Preferably, the bio-compatible oil or fat further comprises alfa-tocopherol.
Patent DE-60312215-D1 (DE)
Inventor: BIRKE FRANZ
IPC: A61K31/5415
Filed: 2003-11-18
Granted: 2007-04-12
Abstract: The invention relates to a pharmaceutical formulation comprising a LTB4 antagonist having a hydroxy and a benzamidine group or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof, in particular a compound of formula (I) wherein R and A are as defined in the claims, or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof (1) and at least one cyclooxygenase-2 inhibitor, a combined cox1/2 inhibitor or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof (2), and a pharmaceutically acceptable carrier or excipient, and optionally one or more other therapeutic ingredients.
Patent DE-60316206-D1 (DE)
IPC: C10J3/30
Filed: 2003-01-17
Granted: 2007-10-25
Abstract: A furnace is formed of the total circular section of the endless screw and the primary oxidizing air arrives in the furnace from outside its circular wall and/or in the center of the furnace.  A co-current gasifier comprises an endless screw (1) feeding fresh material to be gasified, with a vertical endless screw (2) transporting material from bottom to top. The gasifier has a furnace at the top of the outlet from the endless screw, a gasification chamber (11) above the furnace and a device (12) for circulating the material which has already passed through the furnace and the gasification chamber and which is not completely gasified. This returns the material to the fresh material to be gasified so it can be sent across the furnace again. At least two gasifiers can be connected side to side and equipped with a collective turning device for the vertical endless screw. Two coupled gasifiers form a base module which itself can be coupled to a number of similar modules to form a gasification device containing a number of gasifiers. The vertical screws for all the gasifiers are driven by a collective turning device such as a horizontal axle (6) placed in the plane of symmetry of each pair of gasifiers, equipped with a helical gear for each pair of gasifiers and driving a gear fixed to the vertical axle of each screw in each gasifier. The feed screw is horizontal and is connected to the bottom of the vertical screw so as to push the material to be gasified to the base of the screw coils. The feed screw is placed in the vertical plane of symmetry for each pair of gasifiers and extends the length of the gasification device, collectively feeding all the gasifiers the device contains. The device for circulating material is a horizontal endless screw which pushes the material which has not yet been completely gasified out of the gasification chamber and returns it in the action zone of a vertical screw carrying the material from bottom to top. The horizontal evacuation screws of the pair of gasifiers are coaxial and feed the material in opposite directions towards the center of the module, where an opening (21) sends it to the vertical screw carrying fresh material. If the directions of rotation of the horizontal evacuation screws is reversed these move the incombustible material which needs to be eliminated out of the gasification device to where this material is removed. At least two modules are coupled together and preferably four or more. The diameter of the vertical transport screw is 100-200 mm and more. The axes of the screws of the coupled pair of gasifiers form an angle between them of alpha between 1-20 degrees.
Patent DE-60317544-D1 (DE)
Inventor: MCMILLEN ROBERT E
IPC: F28F9/013
Filed: 2003-07-15
Granted: 2007-12-27
Abstract: A static mixer ( 10 ) is provided with a first grid ( 14 ) having one or more crossing elements ( 16 ) and one or more slots and a second grid ( 14 ) having one or more crossing elements ( 16 ) and one or more slots. The crossing elements ( 16 ) of the first grid ( 14 ) are arranged at intersecting angles to the crossing elements ( 16 ) of the second grid ( 14 ). At least one elongated connector ( 18 ) is positioned between and secured to adjacent crossing elements ( 16 ) of the first grid ( 14 ) and crossing elements ( 16 ) of the second grid ( 14 ). The grids may further be arranged such that each crossing element of one grid intersects a slot in the other grid.
Patent DE-60321683-D1 (DE)
Inventor: FELT JEFFREY C
IPC: A61F2/30
Filed: 2003-07-10
Granted: 2008-07-31
Abstract: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed components adapted for insertion and placement into the body and at the joint site. The system includes a method and related components and/or devices in the form of a kit that can be used to provide or perform some or all of the steps of: a) preparing a joint to receive an implant, b) determining an appropriate implant size for a particular joint, c) determining an appropriate implant thickness, d) inserting the implant into the joint, and/or e) securing the implant within the joint to a desired extent. One or more of the various components and devices, including optionally one or more implants themselves, can be provided or packaged separately or in varying desired combinations and subcombinations to provide a kit of this invention. In turn, a kit can include, or be used in combination with, one or more corresponding devices or components that will already exist in the surgical suite, and that can optionally be sterilized for re-use in subsequent procedures. The selection and use of components, devices and/or implants within a kit of this invention is facilitated by the coordination of various features in the manner described, including appearance, size and configuration.
Patent DE-60322324-D1 (DE)
Inventor: MINKO PETER
IPC: B05B5/04
Filed: 2003-10-17
Granted: 2008-09-04
Abstract: An electrode ring (3) suitable for providing electrostatic assistance to the high-speed rotary application of spray coatings and having electrode fingers (4) comprising electrode tips (5), wherein the electrode ring (3) is constructed so as to be capable of performing rotational movements about the axis directed through the centre of the circle thereof.
Patent DE-60322719-D1 (DE)
Inventor: YALKINOGLU OEZKAN
IPC: C07K14/47
Filed: 2003-08-11
Granted: 2008-09-18
Abstract: A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific markers in body fluids (e.g. CSF), using mass spectrometric analysis (SELDI-TOF MS). The specific markers are: human cystatin C, human beta-2-microglobulin, human myoglobin neurosecretory protein VGF or fragments of these proteins.
Patent DE-60325101-D1 (DE)
Inventor: ROSSIN PAOLO
IPC: G02C5/22
Filed: 2003-10-29
Granted: 2009-01-15
Abstract: A frame for eyeglasses comprising a lens supporting structure (12) and two temples (13) each connected laterally to said lens supporting structure (12) by means of a hinge device (14). According to the invention, said hinge device (14) comprises a first magnetic element (15) applied integral with said lens supporting structure (12) and a second magnetic element (16) applied integral with said temples (13), said first and said second magnetic element (15, 16) being engaged with each other to allow relative movement between said temples (13) and said lens supporting structure (12).
Patent DE-60325886-D1 (DE)
Inventor: PICCIRILLI ANTOINE
IPC: A61P17/00
Filed: 2003-11-25
Granted: 2009-03-05
Abstract: Composition (A) contains at least one N-(2-hydroxyalkyl)-carbamic acid derivative (I).  Composition (A) contains at least one carbamic acid derivative of formula (I).  R1, R2, R'2, R3, R'3  =  H or 1-30C alkyl (optionally containing one or more ethylenic and/or acetylenic unsaturations(s) and optionally substituted by one or more OH);  R4, R5  =  H or -CO-Rx; and Rx  =  1-30C alkyl (optionally containing one or more ethylenic and/or acetylenic unsaturations(s) and optionally substituted by one or more OH).
Patent DE-60326021-D1 (DE)
Inventor: TANIHARA MASAO
IPC: C07K1/04
Filed: 2003-02-25
Granted: 2009-03-19
Abstract: A process for producing a novel polypeptide, which comprises 
reacting a peptide component (A) represented by the following formula (1a) with a peptide componant (B) represented by the following formula (2a) and a compound (C) represented by the following formula (3a), as an optional component:  
 X-(Pro-Y-Gly) n -OH(1a)  
wherein "X" represents H or the group HOOC-(CH 2 ) m -CO-, ("m" denotes an integer of 1 to 18), "Y" represents Pro or Hyp, and "n" denotes an integer of 1 to 20,  
 X-(Z) r -OH(2a)  
wherein "X" represents H or the group HOOC-(CH 2 ) m -CO-("m" denotes an integer of 1 to 18), "Z" represents a peptide chain comprising 1 to 10 amino acid residue(s), and "r" denotes an integer of 1 to 20,  
 H 2 N-R-NH 2 (3a)  
wherein "R" represents a linear or branched alkylene group, 
wherein the ratio of the peptide component (A) relative to the peptide component (B) [the former (A)/the latter (B)] is 100/0 to 30/70 (mol%); provided that 
in the case where "X" represents the group HOOC-(CH 2 ) m -CO-("m" has the same meaning as defined above) in the formula (1a) and/or (2a), the amount of the compound (C) is substantially 1 mol relative to 1 mol of the total molar amount of the peptide component (A) and/or the peptide component (B); and 
in the case where "X" represents H in the formula (1a) and/or (2a), the reaction is conducted without the compound (C).  The present invention provides a collagenous polypeptide which is free from a risk of an infection by a pathogenic organism (or a causative factor) or anundesirable side effect, and which has a high safety.
Patent DE-60330857-D1 (DE)
Inventor: LEVY FINN OLAV
IPC: A61K31/5365
Filed: 2003-05-16
Granted: 2010-02-25
Abstract: This invention provides the use of a 5-HT4 receptor antagonist in the manufacture of a medicament for treating or preventing heart failure. Particular heart disorders to be treated are selected from the group comprising chronic heart failure, congestive heart failure, chronic congestive heart failure and heart failure resulting from ischaemic heart disease. Methods of treating heart failure using 5-HT4 receptor antagonists and pharmaceutical compositions containing 5-HT4 receptor antagonists are also provided.
Patent DE-60330895-D1 (DE)
Inventor: LEDEBOER MARK
IPC: C07D409/12
Filed: 2003-11-03
Granted: 2010-02-25
Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.
Patent DE-60332845-D1 (DE)
Inventor: SODE KOJI
IPC: C12R1/40
Filed: 2003-08-20
Granted: 2010-07-15
Abstract: This invention relates to a process for preparing glucose dehydrogenase. The preparation process comprises introducing the DNA containing the sequence described in SEQ ID NO. : 1 coding for the  alpha  subunit, which has a glucose dehydrogenase activity, and the  beta  subunit, which is an electron-transfer protein, into a microorganism belonging to the genus Pseudomonas to create a transformant, and culturing this transformant to produce a first glucose dehydrogenase containing the  beta  subunit and a second glucose dehydrogenase not containing the  beta  subunit. The  alpha  subunit has a molecular weight of approximately 60kDa for example as determined by SDS-polyacrylamide gel electrophoresis under reducing conditions. The  beta  subunit has a molecular weight of approximately 43kDa for example as determined by SDS-polyacrylamide gel electrophoresis under reducing conditions.
Patent DE-60333860-D1 (DE)
Inventor: RIVIERE BERTRAND
IPC: B23C5/24
Filed: 2003-10-06
Granted: 2010-09-30
Abstract: A milling tool includes a rotary milling body forming pockets for receiving respective cutting inserts. Optional cassettes can be mounted in the pockets to receive the inserts. Each insert includes two side surfaces interconnected by four edge surfaces. The insert is double-sided in that each side surface includes two pairs of cutting edges. Each pair of cutting edges includes major and minor cutting edges meeting each other at a cutting corner of the insert. One of the side surfaces includes two cutting corners disposed at opposite ends of one of the edge surfaces, and the other side surface includes two cutting corners disposed at opposite ends of another, opposite edge surface. Each of those two opposite edge surfaces includes a recess for receiving an abutment surface situated at the respective pocket, for defining a stop surface for the insert from moving in a direction parallel to the axis of rotation.
Patent DE-68900833-D1 (DE)
Inventor: FRIEDRICH PERROT
IPC: G04B37/08
Filed: 1989-06-24
Granted: 1992-03-26
Abstract: The frame 7 is a flat metal disc with central and peripheral openings 5 for the anchoring of the packing 9 of cylindrical form. The base 14 of the clock case is provided with a profiled circular opening 15 which is adjusted to the diameter of the packing 9. The latter ensures the fastening and the leaktightness of the hatch by means of radial clamping. All the operations for manufacturing the hatch 10 and positioning it are performed mechanically, without manual intervention and are automated. 
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Patent DE-68909459-D1 (DE)
Inventor: PRALUS GEORGES
IPC: H05B6/80
Filed: 1989-03-02
Granted: 1993-11-04
Abstract: Cooking and reheating. 
<??>The cooking/reheating apparatus is characterised in that it consists in delimiting, in the application cavity (4), a cooking/reheating enclosure (11) open at the front of the oven at least where it coincides with the window of the door and intended to contain the products, by means of an element (8) which can be inserted into the said cavity, comprising at least one wall interposed between the enclosure and the generator and consisting of a porous material (9) permeable to microwave energy and provided with a waterproof coating (10), except on its face (8a) pointing towards the enclosure. 
<??>Application to food products. 
<IMAGE>
Patent DE-68913961-D1 (DE)
Inventor: BODINI FRANCESCO
IPC: A01J7/04
Filed: 1989-05-25
Granted: 1994-04-21
Abstract: An automatic teat-washer for cows or other milk animals made in two parts (2, 3) rigidly connectable together, one enclosing a motor unit (11-14) and the distribution circuit (8) of a washing liquid, and the other enclosing the continuation of the distribution circuit and the work unit, consisting of two counter-rotating brushes (18, 19) suitable for causing a sucking action on the teat, to push its tip, with the aid of a diverting idle roller (21), against a third brush (20) positioned downstream of the first two. The same brushes, turning without the washing liquid, cause the removal of the residual liquid from the surface of the teat.
Patent DE-68918075-D1 (DE)
Inventor: LANGELAND JAN-AGE
IPC: G01V1/38
Filed: 1989-06-06
Granted: 1994-10-13
Abstract: PCT No. PCT/NO89/00055 Sec. 371 Date Jan. 30, 1990 Sec. 102(e) Date Jan. 30, 1990 PCT Filed Jun. 6, 1989 PCT Pub. No. WO89/12236 PCT Pub. Date Dec. 14, 1989.A method for determining the position of at least two seismic streamers (S1, S2) in a reflection seismic measuring system, wherein hydroacoustic distance measurements are used which are taken by means of acoustic transceivers provided in vessels (1), buoys (8), floats (5), seismic sources (2) and in the seismic streamers (S1, S2). Absolute reference positions are determined by position determining equipment provided in at least two locations, for instance, on a vessel (1) or a float (5). The acoustic transceivers and the position determining equipment form a three-dimensional structure. The position determination takes place by trilateration between the acoustic transceivers and the determination of at least two reference positions so that there is no dependency on compass bearings or optical visibility, and high redundancy is obtained. The method is particularly suited for application in connection with three-dimensional marine seismic surveys. The method may be integrated with suitable surface navigation systems in order to find the reference positions and provide absolute positions at any point within a marginal error of 5 to 10 m.
Patent DE-68921745-D1 (DE)
Inventor: CLEMENS THOMAS
IPC: G08B13/24
Filed: 1989-12-26
Granted: 1995-04-20
Abstract: The transmitting and/or receiving antenna of an electronic article surveillance system utilizes a paired-lead loop configuration. One lead forms the active loop. The other lead forms a passive loop, which parallels and is mutually coupled to the active loop, but not conductively connected to it. This other lead is resistively loaded. The passive loop of the receiving antenna can also be used to conduct signals between the receiver circuitry and the alarm reporting devices associated with the receiver.
Patent DE-68926492-D1 (DE)
Inventor: CHI FRANK K
IPC: C04B35/80
Filed: 1989-09-21
Granted: 1996-06-20
Abstract: A moldable refractory composition consisting essentially of defined quantities of liquid vehicle; ceramic fiber; inorganic binder derived from a colloidal dispersion; and organic binder which is a high molecular weight polar organic polymer; the liquid vehicle being a solvent for the organic binder and a non-solvent for the ceramic fiber; the composition having defined solid content, defined density, defined viscosity and defined modulus of rupture. Also described are a method of manufacture of the composition, and a method of forming a refractory moldable shape.
Patent DE-69003322-D1 (DE)
Inventor: KAPPAS ATTALLAH
IPC: A61P3/04
Filed: 1990-02-12
Granted: 1993-10-21
Abstract: Cobalt protoporphyrin and cobalt mesoporphyrin are administered to animals to achieve weight loss and improved protein to fat ratio without decrease in hormone concentration.
Patent DE-69007058-D1 (DE)
Inventor: BORNENGO GIORGIO
IPC: C09B47/06
Filed: 1990-12-06
Granted: 1994-04-07
Abstract: Improved catalytic process for the manufacture of copper phthalocyanine by allowing phthalic anyhydride to react with urea and a copper compound, in the presence of a hydrophobic liquid (dispersing agent), characterised by the presence, along with the catalyst and the dispersing agent, of a promoter selected from particular classes of amides, imides, ureas, thioureas, guanidines, amines or sulphoxides.