baber/WOPTO huggingface dataset:
Patent AU-5911499-A (AU)
Title: Leptin induced genes
Inventor: WHITE DAVID
IPC: A61K48/00
Filed: 1999-09-10
Abstract: Six genes whose expression is induced by leptin are disclosed (LIG46; LIG56; Tgtp, encoding a T cell-specific GTP-binding protein; LRG-47, encoding an interferon (IFN) inducible protein; RC10-II, encoding a subunit of a 20S brain proteasome; and Stra13, encoding a retinoic acid inducible protein). These six leptin-inducible genes and the proteins they encode represent targets for the development of therapeutic agents for use in modulating body weight. For example, agents that alter the expression or activity of one or more of the leptin-induced proteins can be used to modulate body weight. Such agents can be identified using cellular, in vitro, or in vivo assays which monitor the expression or activity of one or more of the six leptin-induced proteins. Potentially useful therapeutic agents can also be identified through the use of assays designed to identify agents that bind to one of the leptin-induced proteins. The leptin-induced genes of the invention and the proteins they encode may themselves be useful therapeutically and diagnostically.
Patent AU-5976890-A (AU)
Title: Insecticide compositions containing as active ingredient glufosinate or one of its salts
Inventor: BENOIT MARC
IPC: A01N57/20
Filed: 1990-07-25
Abstract: A method of combatting insects comprising contacting the insects with an insecticidally effective amount of at least one member of the group consisting of glufosinate of the formula    <IMAGE>  I  and its salts.
Patent AU-6053394-A (AU)
Title: New substituted phenoxyisobutyric acids and esters
Inventor: REGNIER GILBERT
IPC: A61K31/35
Filed: 1994-04-18
Abstract: The substituted phenoxyisobutyric acids and their esters of formula I: <IMAGE>  in which:     - X represents an oxygen atom, a sulphur atom or a single bond; - A represents a single bond or a hydrocarbon radical containing from 1 to 9 carbon atoms in a straight or branched chain optionally containing a double bond, a cyclopropyl radical, an oxygen atom or a carbonyl radical, or optionally substituted by a halogen atom or a hydroxyl radical; - R represents a hydrogen atom or an alkyl radical containing from 1 to 6 carbon atoms in a straight or branched chain optionally substituted by one or two hydroxyl radicals;   - R1 and R3:     . each simultaneously represent a hydrogen atom, or . together form a bridge (CH2)n in which n takes the values 1 or 2, or   . R1 represents:     . a methyl radical, or . a single bond which forms a double bond with the group A when the latter is a hydrocarbon radical, and   . in each of these cases, R3 simultaneously represents a hydrogen atom;   - R2 and R6, which are identical or different, each represent a hydrogen atom or a methyl radical; - R4 and R5, which are identical or different, each represent an alkyl radical containing from 1 to 6 carbon atoms in a straight or branched chain; - R7 represents a hydrogen atom or a labile protective group such as, for example, a CH3CO-, C2H5O-CH2- or benzyl radical; and - Z represents a hydrogen or halogen atom or an alkyl or alkoxy radical each containing from 1 to 5 carbon atoms in a straight or branched chain; and, when they exist, the corresponding enantiomers and diastereoisomers, as well as the physiologically tolerable salts of the compounds I with appropriate bases, can be used in therapeutics.d
Patent AU-6066390-A (AU)
Title: Peptides containing diamino-glycols as transition-state mimics
Inventor: THAISRIVONGS SUVIT
IPC: C07K5/107
Filed: 1990-07-09
Abstract: The present invention provides novel peptides. These peptides have a novel non-cleavable transition state insert corresponding to the 10,11-position of the renin substrate (angiotensinogen) of the formula XL8. These peptides are useful as renin inhibitors and as inhibitors of retroviral proteases. Renin inhibitors are useful for the diagnosis and control of renin-dependent hypertension, congestive heart failure, renin-dependent hyperaldosterism, other renin-dependent cardiovascular disorders and ocular disorders. Inhibitors of retroviral proteases, such as the HIV-I protease, are useful for treating diseases caused by retroviruses, such as human acquired immunodificiency disease syndrome (AIDS).
Patent AU-6131994-A (AU)
Title: Excavating tooth
Inventor: JONES LARREN F
IPC: E02F9/28
Filed: 1994-02-02
Abstract: An excavating tooth (10) for use on a wide variety of excavating equipment is comprised of a point (12), an adapter (14) and a sandwich lock pin (16). The pin includes a rigid casing (54) and a plurality of independently depressible protrusions (58, 59). One of the protrusions (58) resiliently engages a face (22) defined on the nose of the adapter to tighten the connection of the point on the nose. One other of the protrusions (59) extends into an opening (50) defined by the point to secure the lock pin to the point. With respect to an external locking tooth, the opening (50) defined in the point includes a pair of bosses (155a, 155b) which define a reduced portion of the opening. The reduced portion matingly receives and holds the ends of the rigid casing of the pin. The independent locking of the pin and the mating receipt of the casing in the point opening reduces the likelihood of pin loss due to overloading of the elastomeric material, wearing of the components or jacking forces.
Patent AU-6338890-A (AU)
Title: Carton and blank for making the same
Inventor: CURRY ERNEST
IPC: B65D5/06
Filed: 1990-09-07
Abstract: A carton made from a single blank of cardboard, paperboard or the like has a top having a rear portion which is substantially horizontal and a front portion which slopes downwardly and forwardly from said rear portion. The front portion may receive a dispensing spout. The carton is filled by first forming the top of the carton, then filling the carton through the open base and then closing the base. A blank for making the carton has top forming panels, and tuck forming panels connected between the top forming panels and side wall forming panels, the latter connection being by way of a hinge line with two contiguous sections at an angle to each other.
Patent AU-6391894-A (AU)
Title: Naphthalene derivatives
Inventor: CHENARD BERTRAND L
IPC: C07D215/14
Filed: 1994-02-15
Abstract: Compounds of formula (I) where R1 is of formulae (II), (III), or (IV), or (V); R2 is -R4, -O-R4, -O-S(O)2-R4, -NR4R5, R4-(CH2)b-NH(C=X)-(CH2)c-, R4-(CH2)b-O(C=O)NH-(CH2)c-(C=O)NH-, R4-(C=O)NH-(C=O)NH-, -(CH2)b-NH(C=X)-(CH2)c-R4, R4-(CH2)b-O(C=O)-(CH2)c-, -(CH2)b-O(C=O)-(CH2)c-R4, -NH(C=X)NH-R4, R4-O(C=O)O-, -O(C=O)NH-R4, R4-O(C=O)NH-, -(CH2)b-(C=O)-(CH2)c-R4, -NH-S(O)2-R4, -C(OH)R4R5, -CH(OH)-R4, -(C=O)-NR4R5, -CN, -NO2, substituted C1 to C6 alkyl, substituted or unsubstituted C1 to C6 alkenyl, or substituted or unsubstituted C1 to C6 alkynyl, said substituted moieties substituted with a moiety of the formulae -R4, -R4R5, -O-R4, or -S(O)d-R4; R3 is hydrogen, C1 to C6 alkyl, C1 to C6 alkylaryl, or aryl; R4 and R5 are each independently (XV), (XVI), (XVII), hydrogen, -CF3, C1 to C6 alkyl, C1 to C6 alkylaryl, with the proviso that when R2 is -R4 or -OR4, R4 is not hydrogen or C1 to C6 alkyl. These compounds are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and antagonists and may be used in the treatment of depression, anxiety, eating disorders, obesity, drug abuse, cluster headache, migraine, pain and chronic paroxysmal hemicrania and headache associated with vascular disorders, and other disorders arising from deficient serotonergic neurotransmission. The compounds can also be used as centrally acting antihypertensives and vasodilators.
Patent AU-6636496-A (AU)
Title: Use of 19-nor-vitamin d compounds for the prevention of hyperphosphatemia in kidney disorder patients
Inventor: DELUCA HECTOR F
IPC: A61K31/59
Filed: 1996-07-09
Abstract: The 19-nor-vitamin D analogs, and particularly 19-nor-1 alpha ,25-dihydroxyvitamin D2, possess low calcemic and phosphatemic activity while also having the ability to suppress parathyroid hormone (PTH) production. The suppressive effect on PTH secretion of these 19-nor analogs without significant changes in serum calcium or serum phosphorus make them ideal tools for the treatment of secondary hyperparathyroidism in patients having kidney disorders.
Patent AU-6694590-A (AU)
Title: Knot tying machine
Inventor: HANLAN ALLAN JAMES
IPC: A22C11/12
Filed: 1990-11-23
Abstract: A machine for automatically tying knots in a strand of material, particularly for tying a knot in the end of a sausage casing. The machine (Fig. 1b) comprises a gripper 11 which pulls out a strand 9 from a shirred collagen casing 10 and at the same time twists it. A ring 16 carries wrap-around rollers 17 which wrap the strand 9 around a pair of jaws 15. A tail gripper and cutter 19 grips the tail of the twisted strand and cuts off any unwanted portion. Tail gripper 19 then inserts the end of the strand through the loop of the strand and it is pulled right through to tighten the knot by jaws 15 which close on to the strand.
Patent AU-6695996-A (AU)
Title: Process for the regeneration of an aqeous process liquid of the amine-oxide process
Inventor: HARFMANN PETER
IPC: C07D295/02
Filed: 1996-08-16
Abstract: The invention concerns a method of destroying N-nitrosomorpholine in an aqueous solution containing N-nitrosomorpholine and a peroxide oxidizing agent, the method being characterized in that the aqueous solution is irradiated with ultraviolet light essentially having a wavelength of 254 nm.
Patent AU-6715500-A (AU)
Title: Water-dispersible agrochemical compositions
Inventor: MISSELBROOK JOHN
IPC: A01N43/36
Filed: 2000-08-25
Abstract: The invention relates to novel compositions of biologically active agents containing less than 50% by weight of a low use rate agrochemical active and a dispersing agent, which exhibit enhanced bio-availability on dilution and application in water.
Patent AU-6778494-A (AU)
Title: Cell test for alzheimer's disease
Inventor: ALKON DANIEL L
IPC: G01N33/68
Filed: 1994-05-02
Abstract: The present invention is a method for the diagnosis of Alzheimer's disease using human cells. Specifically, the method detects differences between potassium channels in cells from Alzheimer's patient and normal donors, and differences in intracellular calcium concentrations between Alzheimer's and normal cells in response to chemicals known to increase intracellular calcium levels.
Patent AU-6896198-A (AU)
Title: Method for treating cerebral focal stroke
Inventor: BYMASTER FRANKLIN PORTER
IPC: A61K31/55
Filed: 1998-04-08
Abstract: The present invention provides a method for treating cerebral focal stroke comprising administering a therapeutically effective dosage of olanzapine or a pharmaceutically acceptable salt or solvate thereof.
Patent AU-6923398-A (AU)
Title: Novel copper(i) precursors for chemical deposit in gas phase of metallic copper
Inventor: DOPPELT PASCAL
IPC: C07F7/08
Filed: 1998-03-13
Abstract: PCT No. PCT/FR98/00518 Sec. 371 Date Dec. 15, 1999 Sec. 102(e) Date Dec. 15, 1999 PCT Filed Mar. 13, 1998 PCT Pub. No. WO98/40387 PCT Pub. Date Sep. 17, 1998The invention concerns complex compounds of oxidised copper (+1) stabilised by a ligand for the gas phase chemical deposit of copper in which copper is coordinated with a  beta -diketonate and the ligand is an alkyne of which the triple bond is partially deactivated by one or two groups slightly attracting the electrons by said alkyne.
Patent AU-7002394-A (AU)
Title: Immunoglobulin g concentrate for therapeutical use and method for producing same
Inventor: BURNOUF MIRYANA
IPC: C07K16/06
Filed: 1994-06-13
Abstract: PCT No. PCT/FR94/00699 Sec. 371 Date Mar. 25, 1996 Sec. 102(e) Date Mar. 25, 1996 PCT Filed Jun. 13, 1994 PCT Pub. No. WO94/29334 PCT Pub. Date Dec. 22, 1994The invention relates to a plasma derived immunoglobulin G concentrate and to the process for producing said concentrate. The process comprises a series of chromatographic separations but no ethanol precipitation. The process also includes a viral inactivation treatment. The invention relates to the immunoglobulin G concentrate obtained by said process which is of therapeutic quality suitable for any use especially for intraveinous injection.
Patent AU-7063600-A (AU)
Title: Low oxygen refractory metal powder for powder metallurgy
Inventor: KUMAR PRABHAT
IPC: H01G9/042
Filed: 2000-08-18
Abstract: Process for producing formed Ta/Nb powder metallurgy products using Ta and/or Nb hydride powders with an oxygen content greater than a target level, e.g., 300 ppm, heating the metal hydride in the presence of another metal having a higher affinity for oxygen removing the other metal and any reaction byproducts, to form a metal powder with an oxygen content less than the target level and forming a metallurgical product from said oxygen reduced Ta/Nb powder with an oxygen content less than the target level.
Patent AU-7167287-A (AU)
Title: Process for strengthening and sealing geological formations
Inventor: MANN MAX
IPC: E21B33/138
Filed: 1987-03-31
Abstract: The present invention is directed to a process for strengthening and sealing geological formations which are moist or contain water, in particular loose stone, by the injection of a mixture which reacts to form polyurethane, characterized in that a polyisocyanate component is injected before injection of the reaction mixture.
Patent AU-7171201-A (AU)
Title: Method and system for modeling geological structures using an unstructured four-dimensional mesh
Inventor: KENNON STEPHEN R
IPC: G06T17/05
Filed: 2001-07-29
Abstract: A method and system are disclosed for high-resolution modeling of a well bore in a reservoir. An embodiment of the present disclosure comprises the steps of constructing a first unstructured mesh having a plurality of n-dimensional simplices corresponding to a first modeled system (space), defining a surface bounding a second modeled space, identifying a subset of the plurality of n-dimensional simplices of the first mesh that are intersected by the surface, and modifying the subset of simplices so as to adapt the first mesh such that it comprises a second mesh and a third mesh, wherein the second mesh comprises a set of simplices located entirely interior to the surface and wherein the third mesh comprises another set of simplices located entirely exterior to said surface.
Patent AU-7241691-A (AU)
Title: Use of insulin sensitizing agents to treat hypertension
Inventor: COLCA JERRY R
IPC: A61K31/00
Filed: 1991-01-23
Abstract: The present invention provides a method for treating hypertension in insulin resistant patients comprising the administration of an insulin sensitizing agent, particularly ciglitazone or pioglitazone.
Patent AU-7264096-A (AU)
Title: Soft filled tissue paper with biased surface properties
Inventor: VINSON KENNETH DOUGLAS
IPC: D21H17/68
Filed: 1996-10-10
Abstract: Soft, strong, and low dusting tissue paper webs useful in the manufacture of soft, absorbent sanitary products such as bath tissue, facial tissue, and absorbent towels are disclosed. The tissue papers comprise fibers such as wood pulp and a non-cellulosic, water insoluble particulate filler such as kaolin clay and possess biased surface properties.
Patent AU-7299587-A (AU)
Title: Zinc and/or lead salts of carboxylic acids and their use as corrosion inhibitors
Inventor: LIEDEK EGON
IPC: C09D5/08
Filed: 1987-05-15
Abstract: Novel zinc, lead or zinc/lead salts of carboxylic acids of the formula   <IMAGE>   where Y is -CO- or -SO2-, X is H or -NO2 and n is 1 or 2. The salts, in particular the basic salts of (I), are useful corrosion-inhibitors for coating systems, especially for aqueous or water-dilutable systems.
Patent AU-7347691-A (AU)
Title: Stackable bottle case in plastic material
IPC: B65D1/24
Filed: 1991-03-01
Abstract: PCT No. PCT/EP91/00380 Sec. 371 Date Sep. 17, 1992 Sec. 102(e) Date Sep. 17, 1992 PCT Filed Mar. 1, 1991 PCT Pub. No. WO92/15488 PCT Pub. Date Sep. 17, 1992.In a stackable bottle crate from plastic material, the side walls are reinforced by vertical hollow profiled columns which are extended up to the upper marginal edge of the crate side walls and together with the upper marginal edge from a circumferential piling edge for load reduction.
Patent AU-7490294-A (AU)
Title: Antipsychotic treatment
Inventor: BYMASTER FRANKLIN PORTER
IPC: A61P43/00
Filed: 1994-08-15
Abstract: The present invention relates to a novel method for treating a mammal suffering from or susceptible to schizophrenia and schizophreniform diseases comprising administering to said mammal an effective amount of a compound of formula (I), wherein Z<1> is oxygen or sulphur.
Patent AU-7574601-A (AU)
Title: Tissue implant
Inventor: THOMSON BRIAN MARK
IPC: A61K35/12
Filed: 2001-07-30
Abstract: The invention relates to a medicament and method of treating cartilage defect. The invention also relates to an implant for treating cartilage defect.
Patent AU-7727094-A (AU)
Title: Pneumatic pressure automatic braking mechanism
Inventor: BOWSER GREGORY ALAN
IPC: F01D15/06
Filed: 1994-09-13
Abstract: A braking mechanism for a rotary apparatus having a housing adapted to receive a pressurized fluid and a rotor rotatably mounted in the housing. The braking mechanism enables the rotor to rotate in the housing in response to the receipt of the pressurized fluid and inhibits the rotor from rotating in the absence of the receipt of the pressurized fluid.
Patent AU-7806287-A (AU)
Title: Arrangement for a spring fracture safety device for an overhead sliding door
Inventor: BENGTSSON FRED
IPC: E05D/
Filed: 1987-08-05
Abstract: An arrangement for a spring fracture safety device intended for a closing element for an overhead sliding door or similar capable of being moved between a raised and a lowered end position, which can be attached to a door actuating spring (1) and is controlled by tracks extending along the intended path of movement of the door, continuous guide rollers or similar control devices. The spring fracture safety device functions efficiently and reliably, irrespective of where along the length of the spring fracture occurs. One free end (1A) of the door actuation spring is capable of being attached via a movement transfer device (9) to a release device (7) for a door braking element (8) interacting with a number of said guide rollers, etc., which braking element can be caused to move between a position (I) in which it is ready for release and a braking position, in which positions the element (8) is respectively kept withdrawn, so that said guide rollers are able to pass freely along the tracks in question, and is caused to project, so as to produce a braking effect by interaction with a door guide roller.
Patent AU-8151382-A (AU)
Title: Fibre reinforced springs
Inventor: MARSH BARRY JOHN
IPC: F16F1/18
Filed: 1982-03-15
Abstract: A method of making leaf springs from fibre reinforced resin composite material, wherein a resin impregnated fibre assembly of a number of individual springs adjacent one another is moulded and treated to cure the resin and then cut into individual springs. The assembly is formed with depressions in the surface thereof along the lines where it is to be cut so the surface fibres remain undisplaced by the moulding process and hence undisturbed by cutting. The invention also provides a mould for treatment of the assembly of resin impregnated fibres including elements which form the surface depressions therein.
Patent AU-8448301-A (AU)
Title: Remedies for heart failure
Inventor: KAWASHIMA KAYOKO
IPC: A61K39/00
Filed: 2001-09-07
Abstract: The present invention provides methods for screening drugs inhibiting the expression of OSF-2 gene or the production or function of the protein encoded thereby and therapeutic agents for heart failure having such effects. Useful methods for diagnosing heart failure can be provided by monitoring the expression or variation of said gene or the production of the protein encoded thereby. The present invention also provides transgenic animals with forced expression of OSF-2 gene and methods for studying changes in gene expression or protein production or the functions of various genes or proteins with the progress of the pathology of heart failure using them and novel therapeutic agents for heart failure.
Patent AU-8496191-A (AU)
Title: Continuous, self-contained mowing system
Inventor: COLENS ANDRE
IPC: A01D34/00
Filed: 1991-09-23
Abstract: PCT No. PCT/BE91/00068 Sec. 371 Date Mar. 23, 1993 Sec. 102(e) Date Mar. 23, 1993 PCT Filed Sep. 23, 1991 PCT Pub. No. WO92/04817 PCT Pub. Date Apr. 2, 1992.The invention relates to an automatic, self-contained machine for continuously mowing grass. The machine is powered by means of photovoltaic cells (10) and can be wheeled (15) or tracked. A device comprising a microcomputer programmed by an algorithm allows to search for spots where the grass must be cut and to detect the boundaries of the surface to be mown. The obstacles (92) are detected and passed around by analysis of relative movements of an upper panel (9) comprising the photovoltaic cells (10) and a lower frame (1).
Patent AU-8970098-A (AU)
Title: Catalyst having a ketimide ligand
Inventor: MCMEEKING JOHN
IPC: C08F4/659
Filed: 1998-09-03
Abstract: A catalyst system comprises an organometallic complex of a group 4 metal having a ketimide ligand. The organometallic complex preferably also contains a cyclic ligand which forms a delocalized pi-bond with the metal (such as a cyclopentadienyltype ligand). Preferred organometallic complexes may be activated with a so-called "substantially non coordinating anion" to form a low cost cocatalyst system which is excellent for the preparation of olefin copolymers having both high molecular weight and very low density.
Patent AU-9073082-A (AU)
Title: 8-carboxyalkyl-4h-benzo(b)pyran-4-ones
Inventor: BRIET PHILIPPE
IPC: C07D311/30
Filed: 1982-11-19
Abstract: The invention concerns [oxo-4-4H-[1]-benzopyran-8-yl]-alcanoic acids and their derivatives, their manufacture, represented by the formula. <IMAGE>   where AR is hydrogen, a phenyl radical which may or may not be substituted thenyl, furyl, naphthyl, a lower alkyl, cycloalkyl, aralkyl radical; B is a linear or branched lower alkyl radical, either saturated or ethylinically unsaturated; R1 is hydrogen or a phenyl radical; X is hydrogen or a lower alkyl or alkoxy radical and n=1, as well as salts, esters, aminoesters and amides. Compounds and their derivatives may be used as medicines, in particular in the control of tumors.
Patent AU-9192782-A (AU)
Title: (1,2)-heterofused-1,4-benzodiazepine
Inventor: LIEPMANN HANS
IPC: C07D409/04
Filed: 1982-12-24
Abstract: [1,2]-fused 1,4-benzodiazepine compounds are disclosed corresponding to the general formula I    <IMAGE>  I  wherein X is an oxygen or sulfur atom or an optionally substituted imino group, R1 is a hydrogen or halogen atom, lower alkyl radical, a lower alkoxy radical or a nitro group and R2 is a hydrogen or halogen atom, a lower alkyl radical, a lower alkoxy radical or a nitro group, or if R1 is a hydrogen atom, R2 may also be a lower alkylthio radical, or, if R1 is a hydrogen atom and X is a sulfur atom or an imino group, R2 may be a trifluoromethyl radical; or R1 and R2 are bonded to adjacent carbon atoms and together denote a methylenedioxy or ethylenedioxy radical; R3 is an optionally substituted furyl, thienyl, pyrrolyl or pyridyl radical and n is zero or, if R3 is furyl or thienyl, n may be 0 or 1. The compounds may be in the form of their optical isomers or acid addition salts. The compounds exhibit neuroleptic properties. Processes for preparing the compounds and pharmaceutical compositions containing them are also disclosed.