baber/WOPTO huggingface dataset:
Patent CA-2764808-A1 (CA)
Title: Histamine h3 inverse agonists and antagonists and methods of use thereof
Inventor: CHYTIL MILAN
IPC: A61P25/16
Filed: 2010-06-09
Abstract: Provided herein are spiro-cyclic compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, including, e.g., neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as, e.g., histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse).  Pharmaceutical compositions containing the compounds and their methods of use are also provided herein.
Patent CA-2766168-A1 (CA)
Title: Hydraulically locking stabilizer
Inventor: CHESNUTT DENNIS PATRICK
IPC: E21B17/10
Filed: 2010-06-30
Abstract: A downhole tool (100) includes a pressure housing (120) deployed in the bore (115) of a drill collar (110). At least three fins (220) are deployed on the housing (120) and in the tool annulus (115). At least one of the fins (220) includes a floating blade (250) deployed thereon. The blade (250) includes a plurality of radial pistons (260) deployed therein. The pistons (260) are configured such that the surface area of the radially outward facing piston surfaces is greater than the surface area of the radially inward facing piston surfaces. This piston (260) configuration causes the surface area of the radially outward facing blade surface to be less than the radially inward facing blade surface. In operation, hydrostatic pressure exerts a differential force on the pistons (260) and the floating blade (250) thereby urging the pistons (260) radially inward towards the housing (120) and the blade (250) radially outward towards the drill collar (110).
Patent CA-2766308-A1 (CA)
Title: Partial encryption using variable block-size parameters
Inventor: FARKASH EYAL
IPC: G11B20/00
Filed: 2009-12-27
Abstract: A method for data processing, comprising providing a sequence of image frames that is encoded by identifying intra and inter frames in the sequence and applying a variable block size motion compensation (VBSMC) procedure to the inter frames, thereby generating respective parameters representing the inter frames; selectively encrypting the block sizes, using an encryptor, without encrypting all of the parameters representing the inter frames; and outputting encoded data representing the sequence of the image frames and comprising the encrypted block sizes.
Patent CA-2769666-A1 (CA)
Inventor: LEVY ARIE
IPC: A61B17/08
Filed: 2010-07-07
Abstract: The present invention generally relates to devices and methods for reversibly coupling an implant to a deployment device.
Patent CA-2771989-A1 (CA)
Title: Means and method for performing hyperpolarizing gas imaging
Inventor: RAPOPORT URI
IPC: A61M16/00
Filed: 2010-08-25
Abstract: The present invention discloses a system for hyperpolarizing un-polarized gas within an animal. The system comprises hyper polarization means for hyperpolarizing the un-polarized gas, wherein the hyperpolarization of the un-polarized gas is provided in-situ within the analyzed animal.
Patent CA-2773643-A1 (CA)
Title: Weighted rodent bait stations and related methods
Inventor: VICKERY ETHAN
IPC: A01M25/00
Filed: 2009-09-08
Abstract: Rodent bait station assemblies and methods for bundling.
Patent CA-2774475-A1 (CA)
Title: Lassa virus-like particles and methods of production thereof
Inventor: BRANCO LUIS M
IPC: C12Q1/70
Filed: 2010-09-15
Abstract: The instant invention is directed to novel Lassa virus-like particle (VLP) compositions and methods of production thereof. The inventive VLPs comprise, for example, the Lassa virus (LASV) Z matrix protein, glycoproteins (GPs)-I and -2, and nucleoprotein (NP). A novel method for producing these VLPs comprises constructing multicistronic plasmids for the expression of VLP protein components from a single vector. One example is a tricistronic vector containing DNA sequences encoding the LASV Z, GPC and NP proteins. The VLPs provided by the present invention can be used for research, therapeutic and diagnostic purposes.
Patent CA-2775290-A1 (CA)
Title: Methods and compositions for selectively treating skin
Inventor: DALY SUSAN
IPC: A61Q1/02
Filed: 2010-09-22
Abstract: This invention relates to compositions, methods and kits for selectively depositing a benefit agent on skin without depositing the benefit agent on the hair. The method relates to exposing the skin to a composition containing anionic proteins, anionic polymers, anionic dyes, anionic pigments, or mixtures thereof which have an isoelectric point of less than about 4.5, the compositions having a pH of about 3.5 to about 5.5. In accordance with the methods of this invention, the benefit agent becomes deposited on the skin; however, any hair that is also contacted by the benefit compositions remains substantially untreated.
Patent CA-2779207-A1 (CA)
Inventor: HANTSCHEL THOMAS
IPC: G01V9/00
Filed: 2012-06-08
Abstract: Prospect assessment and play chance mapping tools are provided. For assessing potential resources, example systems provide dynamically linked chance maps, transformed in real time from geological properties. Input geological maps or other data are dynamically linked to resulting chance maps, so that changes in the input maps automatically update the chance map in real time. Users can generate a custom risk matrix dynamically linking geological maps with chance maps via comprehensive interface tools, dropping maps directly into the matrix. A transform may programmatically converts the geologic domain to the chance domain. The user can navigate input maps, select areas of interest, and drag-and-drop geologic properties directly into an uncertainty engine and distribution builder for uncertainty assessment based directly on geologic reality. A merge tool can programmatically unify multiple geological interpretations of a prospect. The merge tool outputs a single chance of success value for multiple geologic property values at each grid node.
Patent CA-2779304-A1 (CA)
Inventor: LOWE MARK
IPC: A61F7/02
Filed: 2010-10-22
Abstract: La présente invention se rapporte à une enveloppe thérapeutique à température contrôlée pour le traitement d'au moins une partie d'un corps vivant comprenant une vessie remplie de fluide comprenant un orifice d'entrée, un orifice de sortie et au moins un canal fluidique reliant l'orifice d'entrée à l'orifice de sortie; et un élément thermo-isolant sur la vessie remplie de fluide de façon seulement directement adjacente à l'orifice d'entrée et s'étendant le long du ou des canaux fluidiques. L'enveloppe thérapeutique peut être conçue pour compenser un delta de température dans l'enveloppe. L'enveloppe thérapeutique peut comprendre une couche isolante d'un ou plusieurs éléments isolants. La couche isolante est dimensionnée et configurée pour avoir différents coefficients de transfert de chaleur. La couche isolante peut avoir diverses épaisseurs et divers matériaux pour obtenir divers taux de transfert de chaleur. La présente invention se rapporte également à un procédé d'administration d'un traitement à température contrôlée à une partie anatomique.
Patent CA-2779932-A1 (CA)
Title: Lockable core barrel head for drilling system and survey instrument assembly provided with a connection link for arrangement in a drilling system
Inventor: BORG EIRIK
IPC: E21B17/02
Filed: 2010-11-04
Abstract: Core barrel head (20) for connection to a core barrel for collecting core samples, and for connection to a latch assembly (14), to mount a drill assembly in a bore hole, with a sleeve (27) for carrying the inner tube. A controllable locking device (38, 39) is arranged inside the core barrel head (20) for locking the sleeve (27) in a fixed rotational position relatively to the attached latch assembly (14), to allow measurement of the inclination and the orientation of the core. The invention also includes a survey instrument assembly (12) provided with a connection link (70) for connection to a spearhead (11), drill pipe, latch assembly (14), core barrel head (20) or other drilling or geotechnical equipment.
Patent CA-2780014-A1 (CA)
Inventor: PETERSON DAVID K L
IPC: A61N1/05
Filed: 2010-11-08
Abstract: A method, programmer (16) for a neurostimulator (14), and neurostimulation kit (12, 14) are provided. The kit comprises a neurostimulator (14), and a plurality of elongated lead bodies (12) configured for being coupled to the neurostimulator, each having a plurality of proximal contacts and a plurality of distal electrodes (26) respectively electrically coupled to the proximal contacts, wherein an in-line connectivity between the electrodes (26) and proximal contacts carried by the different lead bodies (12) differs from each other. Electrical energy is conveyed between the electrodes (26) of the selected lead body (12) and the tissue, an electrical fingerprint is measured at the proximal contacts of the selected lead body (12) in response to the conveyed electrical energy, and the selected lead body (12) is identified based on the measured electrical fingerprint. These steps can be performed by the programmer (16).
Patent CA-2780343-A1 (CA)
Title: Visualization instrument
Inventor: MCGRAIL THOMAS W
IPC: A61B1/05
Filed: 2010-11-29
Abstract: A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses.
Patent CA-2782776-A1 (CA)
Title: Biomarkers for atherosclerosis
Inventor: PFUETZNER ANDREAS
IPC: G01N33/50
Filed: 2009-12-04
Abstract: The invention provides compositions and methods for defining the state of atherosclerotic degeneration processes for the purposes of detection, severity assessment, monitoring and treatment. The states of atherosclerotic degeneration processes are identified by means of a biomarker panel particularly suited for detecting atherosclerotic degeneration processes. The simultaneous use of multiple markers with independent classification power will increase the performance of the panel in identifying atherosclerosis compared to other panels.
Patent CA-2783039-A1 (CA)
Inventor: HASSELL JON P
IPC: B65D1/34
Filed: 2012-07-09
Abstract: A bakery tray includes a base. A front wall extends upward from a front edge of the base. Side walls extend upward from side edges of the base. A rear wall extends upward from a rear edge of the base. The rear wall includes an inner panel portion and an outer lip portion that protrudes outward and then downward from an uppermost edge of the inner panel portion. A plurality of ribs connect the inner panel portion to the outer lip portion. In one feature, the plurality of ribs may include an increased concentration of the ribs in the center of the tray.
Patent CA-2783720-A1 (CA)
Title: Alcohol-based gas stripping process
Inventor: AROONWILAS ADISORN
IPC: B01D53/96
Filed: 2010-12-08
Abstract: The present disclosure relates to a method for stripping acid gases, exemplified by carbon dioxide, from absorption media and/or adsorption media using an alcohol selected from those having a boiling point lower than the boiling point of the absorption medium and/or adsorption medium.
Patent CA-2785048-A1 (CA)
Title: Systems and methods for accessing and controlling media stored remotely
Inventor: BLOKHIN YURIY
IPC: G06V30/224
Filed: 2010-12-21
Abstract: In some embodiments, an apparatus includes a server that stores a set of media files. The server is configured to send an authentication code to a first communication device in response to a request from the first communication device to access the set of media files such that the first communication device can present the authentication code to a user. The server is configured to associate an identifier of a second communication device with the first communication device such that a user of the second communication device can authorize access to the set of media files from the first communication device by sending the authentication code to the server using the second communication device.
Patent CA-2786093-A1 (CA)
Inventor: NIKLEWSKI PAUL J
IPC: G16H10/60
Filed: 2012-08-14
Abstract: A medical system includes a sedation system and a central station in communication with the sedation system. The sedation system includes a monitoring unit and a drug delivery unit. The monitoring unit is operable to monitor at least one physiological parameter of a patient. The drug delivery unit is operable to deliver drugs to the patient based on data from the monitoring unit. The central station is operable to store patient related data and access a plurality of sedation systems. The central station may remotely control drug delivery through sedation systems, remotely provide voice instructions through sedation systems, display video feeds from sedation systems, respond to queries from sedation systems, and/or provide other functionalities. The system may also include an instrument that is operable to perform surgical and/or therapeutic procedures on the patient. The sedation system may provide power to the instrument and/or otherwise communicate with the instrument.
Patent CA-2789004-A1 (CA)
Inventor: HECHT GIL
IPC: B23B27/00
Filed: 2011-01-31
Abstract: In a tool coupling (20) in the form of a cutting tool used for internal machining operations, a second component (24) having a single cutting portion is clamped to a first component (22) by means of a clamping screw (26). The second component (24) has a mounted surface with three male engaging members (36) interfacing with three female engagement members (32) on a mounting surface of the first component (22). Each of the three female engagement members (32) has two sets of side surfaces located on a shared portion, the shared portion exhibiting mirror symmetry about a first plane, and each set of side surfaces having two opposing flank surfaces separated by the first plane. Only one of the two flank surfaces of each of the two sets of side surfaces is in clamping contact with a corresponding abutment surface on each of the three male engaging members.
Patent CA-2791109-A1 (CA)
Inventor: THROSBY MARK
IPC: A61K39/395
Filed: 2012-09-25
Abstract: A method is described for generating binding molecules. A defined population of binding molecules is produced using at least the following steps: (a) providing a population of B cells expressing a limited VL repertoire wherein essentially all B cells carry at least one VL; (b) obtaining nucleic acids from said B cells; (c) optionally, amplifying nucleic acids encoding immunoglobulin heavy chain variable regions in said sample; (d) at least partial sequencing of essentially all obtained nucleic acids of step (b) or amplification products of step (c); (e) performing frequency analysis of sequences from step (d); (f) selecting desired VH sequences; (g) providing a host cell with at least one vector comprising at least one of said desired VH sequences and/or at least one VL sequence of said limited VL repertoire; (h) culturing host cells and allowing for expression of VH or VL polypeptides; and (i) obtaining said binding molecules.
Patent CA-2793157-A1 (CA)
Title: Modular placement device of a feed station
Inventor: GESERICH FRANK
IPC: B07C5/02
Filed: 2012-10-23
Abstract: The invention concerns a modular placement device (1) of a feed station, wherein a drawing device is provided in the ejection region of the feed station, which drawing device has at least one driven ejection roller, characterized in that the modular placement device (1) is equipped with a separate housing (10) and is stationed upstream (in terms of the mail flow) of the feed station (2); the housing (10) has a shaft-shaped cavity (15) near the rear wall (17) of the housing of the modular placement device and a pressure element (14) borne such that it can pivot and can be plugged into the cavity (15), which pressure element exerts a pressure force on a stack (3) of goods to be isolated at the transition to the ejection region, wherein the underlying good is pressed with such a force against the at least one driven ejection roller of the feed station that a propulsion of the good is achieved, wherein the weight loss of the stack due to the removal of the good for isolation of the stack is counteracted by the pressure element.
Patent CA-2794771-A1 (CA)
Inventor: KORODI GERGELY FERENC
IPC: H04N7/50
Filed: 2011-05-20
Abstract: Methods and systems are described for combining sources in a data compression system. In a system in which a context model results in the production of multiple sources or symbols, each source being associated with a probability estimate, sources may be combined by defining another, reduced size, set of probabilities. The new set of probabilities may be a subset of the predefined set of probabilities provided by the context model. Minimizing relative entropy may be a basis upon which to define a mapping of predefined probabilities to the new set of probabilities. An input sequence that was modeled using the context model may then be entropy encoded and entropy decoded using the new set of probabilities based on a mapping between the new probabilities and the predefined probabilities.
Patent CA-2795099-A1 (CA)
Inventor: HEDRICH HANS CHRISTIAN
IPC: A61L26/00
Filed: 2011-04-07
Abstract: The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that - said polymeric component is coated onto a surface of said matrix of a biomaterial, or - said matrix is impregnated with said polymeric material, or - both.
Patent CA-2796879-A1 (CA)
Inventor: DIMARCHI RICHARD D
IPC: A61K38/095
Filed: 2011-06-09
Abstract: A non-enzymatically self cleaving dipeptide element is provided that can be linked to known medicinal agents via an amide bond. The dipeptide will spontaneously be cleaved from the medicinal agent under physiological conditions through a reaction driven by chemical instability. Accordingly, the dipeptide element provides a means of linking various compounds to known medicinal agents wherein the compounds are subsequently released from the medicinal agent after a predetermined time of exposure to physiological conditions. For example, the dipeptide can be linked to an active site of a drug to form a prodrug and/or the dipeptide may comprise a depot polymer to sequester an injectable composition comprising the complex at the point of administration.
Patent CA-2796991-A1 (CA)
Inventor: STRONG H ANDREW
IPC: A61K31/11
Filed: 2011-04-19
Abstract: Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
Patent CA-2797764-A1 (CA)
Inventor: LEWIS MARC SAMUEL
IPC: G06Q30/00
Filed: 2011-04-28
Abstract: There is disclosed an apparatus configured to provide a chart of content items to a plurality of user devices. The apparatus is configured to enable individual users to temporarily access one or more content items listed in the chart. The apparatus comprises a user device interface configured to communicate with user device applications and a permissions module configured to define user access permissions, including temporary user access permissions, relating to individual ones of the one or more items of content. The apparatus also provides a distribution module configured to implement permissions defined in the permission module in relation to user devices by making available one or more items of content listed in the chart to at least one user device application.
Patent CA-2797938-A1 (CA)
Title: Kit comprising a liquid container and a refill device
Inventor: VAN DIEPEN JACOBUS SIMON PETRUS
IPC: B67D7/00
Filed: 2011-04-20
Abstract: A kit comprising of a container (20) arranged to be in an inverted configuration and having a cap (21) at its lower end, in use, the cap (21) having an outlet orifice extending axially into the container (20) which is selectively sealed at its axially innermost end by a resiliently biased seal, a disc within the outlet orifice on which the seal sits, a plurality of spokes holding the disc in place, so that, with the seal open, flow paths are formed between the outlet orifice, the disc and the spokes; and a refill device, the refill device comprising a nozzle (41) with a plurality of castellations which fit into the outlet orifice of the container (20) between the spokes to lift the seal from the seat to open a flow path for the ingress of liquid.
Patent CA-2801816-A1 (CA)
Inventor: WILDERMUTH STEPHAN
IPC: G01R15/24
Filed: 2011-06-07
Abstract: A voltage sensor comprises an insulator (1) with mutually insulated electrodes (Eij, Es) embedded therein. The electrodes are coaxial and cylindrical and overlap axially along part of their lengths. They are mutually staggered and control the surfaces of electric equipotential such that there is a substantially homogeneous electric field outside the insulator (1) and a substantially homogeneous but higher field within a sensing cavity (7) within the insulator (1). A field sensor (6) is arranged within the sensing cavity (7) to measure the field. This design allows to produce compact voltage sensors for high voltage applications.
Patent CA-2802005-A1 (CA)
Title: Compositions comprising buprenorphine
Inventor: NORTON RICHARD L
IPC: A61P25/04
Filed: 2011-06-06
Abstract: This disclosure relates to a buprenorphine sustained release delivery system for treatment of conditions ameliorated by buprenorphine compounds. The sustained release delivery system includes a flowable composition containing a suspension of buprenorphine, a metabolite, or a prodrug thereof.
Patent CA-2805542-A1 (CA)
Title: Novel process for the preparation of asenapine
Inventor: DALMASES BARJOAN PERE
IPC: C07D313/14
Filed: 2011-07-29
Abstract: The present invention is directed to novel compounds of formula (I) as well as to the process for their preparation. Novel compounds of formula (I) can be converted into asenapine through an efficient process. The invention also relates to novel intermediates used in this process and their use in the preparation of compounds of formula (I).
Patent CA-2806601-A1 (CA)
Inventor: GABRIELOV ALEXEI GRIGORIEVICH
IPC: B01J23/755
Filed: 2011-08-05
Abstract: A hydroprocessing catalyst composition that comprises a chelant treated metal containing support material having incorporated therein a polar additive. The catalyst composition is prepared by incorporating at least one metal component into a support material followed by treating the metal incorporated support with a chelating agent and thereafter incorporating a polar additive into the chelant treated composition.
Patent CA-2811047-A1 (CA)
Inventor: LUU PHUONG VAN
IPC: D21H21/16
Filed: 2011-10-25
Abstract: Described herein is a method of imparting moisture barrier properties to cellulosic tissue sheets, the method comprising: admixing a reactive size chosen from one or more ketene dimers and acid anhydrides in an emollient in an amount of between 1 to 25% reactive size by weight of emollient to prepare a substantially waterless admixture of reactive size and emollient having less than 5% water by total weight of admixture, applying said substantially waterless admixture at a temperature of between 55°C to 110°C to a cellulosic tissue sheet in such an amount that from about 0.5 to about 5 pounds of reactive size are applied per ton of fiber in the sheet, the total amount of emollient added to the sheet being less than 60 pounds per ton of fiber.