baber/WOPTO huggingface dataset:
Patent EP-2600930-A4 (EP)
Title: Injector apparatus and method for drug delivery
Inventor: DE JUAN EUGENE
IPC: A61F9/00
Filed: 2011-08-05
Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.
Patent EP-0168425-A4 (EP)
Inventor: BLACKBURN GEORGE L
IPC: C07C69/30
Filed: 1984-12-18
Abstract: Emulsions lipides contenant des triglycérides à chaîne moyenne pour la nutrition de patients septicémiques ou souffrant d'affections du foie, améliorées par l'inclusion dans les émulsions de triglycérides à chaîne longue. Les émulsions peuvent également contenir des acides aminés dans des proportions avantageuses pour la nutrition de patients souffrant d'affections du foie, ainsi que des hydrates de carbone, des médicaments, des vitamines et des électrolytes.
Patent EP-0263178-A4 (EP)
Inventor: NORLING BRIAN L
IPC: G01P15/13
Filed: 1987-04-15
Abstract: Un accéléromètre comprend un agencement de masse d'essai ayant une languette (26) suspendue à un support (22) et une bobine cylindrique montée sur la languette par un système de montage qui réduit au maximum les erreurs dues aux contraintes thermiques. Le système de montage comprend au moins trois éléments de montage. Chaque élément de montage (114) a une première et une deuxième extrémité et une partie intermédiaire élastique. La première extrémité de chaque élément de montage est reliée à la bobine (78), la deuxième extrémité de chaque élément de montage est reliée à la languette (72) et la partie intermédiaire de chaque élément de montage résiste faiblement aux mouvements radiaux relatifs entre la bobine et la languette et résiste fortement aux mouvements perpendiculaires au sens radial entre la bobine et la languette. La languette est composée de préférence de quartz fondu et le système de montage comprend de préférence une base en quartz fondu (106) reliée directement à la languette et connectée à la deuxième extrémité de chaque élément de montage. La bobine peut être montée sur un noyau de bobine directement relié à la première extrémité de chaque élément de montage.
Patent EP-0273048-A4 (EP)
IPC: G01P15/08
Filed: 1987-06-23
Abstract: L'accéléromètre comprend un corps (10, 16, 12), une masse d'épreuve (18, 30, 32), des moyens de montage comprenant des organes de flexion (20, 22) pour monter la masse d'épreuve sur le corps, et des moyens de détection de force (34, 38). Les organes de flexion permettent à la masse d'épreuve d'effectuer un mouvement de translation par rapport au corps le long d'un axe sensible SA ainsi que la rotation de la masse d'épreuve par rapport au corps autour d'un axe d'articulation HA qui est perpendiculaire à l'axe sensible. L'accélération de l'accéléromètre le long de l'axe sensible se traduit par un mouvement de translation de la masse d'épreuve le long de l'axe sensible. Les moyens de détection de force réagissent à un tel mouvement de translation en produisant un signal représentatif de l'accélération le long de l'axe sensible. Dans un mode préférentiel de réalisation, les moyens de montage comprennent une paire d'organes de flexion à quartz fusionné qui sont dirigés en sens opposés l'un par rapport à l'autre, et les moyens de détection comprennent une paire de transducteurs de force à tige vibrante qui sont connectés à la masse d'épreuve sur les côtés opposés de l'axe d'articulation. Le procédé d'assemblage décrit pour des accéléromètres consiste à former des ponts entre la masse d'épreuve et le corps, les ponts étant retirés après fixation des transducteurs de force.
Patent EP-0451138-A4 (EP)
Title: Reforming using a bound zeolite catalyst.
Inventor: MOHR DONALD H
IPC: B01J29/60
Filed: 1989-01-04
Abstract: Reforming to produce aromatics from aliphatics, using a bound zeolite catalyst containing a Group VIII metal such as platinum, has been found to be extremely sensitive to water, even at water concentrations as low as 3 ppm in the feed, unless certain catalysts having a low water sensitivity index are used. The water sensitivity index (WSI) is described and methods for making catalysts with a low WSI are described. The sulfur content of the feed to the reforming/aromatics production process is preferably below 50 parts per billion. The catalyst used in the reforming process is preferably a high crush strength catalyst and is preferably prepared by steps including treating L zeolite with a binding enhancement agent prior to binding with a binder such as silica, silica/alumina or alumina.
Patent EP-0383926-A4 (EP)
IPC: C08L15/00
Filed: 1989-06-02
Abstract: Tuyau souple à haute pression particulièrement indiqué en tant que conduite hydraulique dans des engins de construction (par exemple des pelles mécaniques). Ce tuyau se compose d'un caoutchouc vulcanisé comprenant un caoutchouc de nitrile fortement saturé présentant une teneur en iode allant jusqu'à 60, du méthacrylate de zinc et un peroxyde organique. Ce tuyau présente, par rapport aux tuyaux utilisés couramment, de meilleures caractéristiques de résistance mécanique, de résistance à la chaleur et d'adhérence aux fils d'acier utilisés comme couche de renforcement du tuyau.
Patent EP-0428630-A4 (EP)
Title: Superconducting metal oxide compositions and processes for manufacture and use
IPC: C01G21/00
Filed: 1989-07-17
Abstract: Compositions having the nominal formula Tle Pba Cab Src Cud Ox wherein a is from about 1/10 to 3/2, b is from about 1 to 4, c is from about 1 to 3, d is from about 1 to 5, e is from about 3/10 to 1, x = (a + b + c + d + e + y) where y is from about 1/2 to 3, are superconducting. Processes for manufacturing such compositions and for using them are disclosed.
Patent EP-0489837-A4 (EP)
Title: Inhibition of lymphocyte adherence to vascular endothelium utilizing a novel extracellular matrix receptor-ligand interaction
IPC: C07K16/28
Filed: 1990-08-31
Abstract: The present invention relates to a method for inhibiting the adhesion of one cell to another comprising interfering with the interaction between the extracellular matrix receptor and its ligand. The invention is based upon the discovery that the  alpha 4 beta 1 extracellular matrix receptor promotes adhesion of lymphocytes to endothelial cells via attachment to a defined peptide sequence. Prior to the present invention, the ligand of the  alpha 4 beta 1 receptor had not been identified, nor had the function of the  alpha 4 beta 1 receptor in lymphocyte attachment been known. By preventing the interaction between the  alpha 4 beta 1 receptor and its ligands using antibodies or defined peptide sequences, the present invention enables, for the first time, specific intervention in the migration of lymphocytes through the vascular endothelium and into tissues. The present invention, therefore, has particular clinical utility in suppression of the immune response, in various specific embodiments of the invention, the adherence of lymphocytes to endothelium may be inhibited systemically, or may, alternatively, be localized to particular tissues or circumscribed areas. Accordingly, the present invention provides for treatment of diseases involving autoimmune responses as well as other chronic or relapsing activations of the immune system, including allergy, asthma, and chronic inflammatory skin conditions.
Patent EP-0448726-A4 (EP)
IPC: C07D307/46
Filed: 1990-10-18
Abstract: On décrit un 2-cyclopenténone substitué en 2 selon la formule (I) ainsi qu'un agent carcinostatique et un stimulateur d'ostéogenèse le contenant en tant qu'ingrédient actif.
Patent EP-0563033-A4 (EP)
Inventor: SCHINSKI WILLIAM L
IPC: C07C22/08
Filed: 1990-10-26
Abstract: On décrit un procédé de préparation de (3-trifluorométhylphényle) acétonitrile en passant par le produit intermédiaire α, α, α-trifluoro-α'-chloro-m-xylène. Ce produit intermédiaire est obtenu par la chloration sélective de α, α, $(a)'-trichloro-m-xylène dans des conditions où le rendement est maximisé et la formation de sous-produits chlorés non-recyclables indésirés est réduite au minimum.
Patent EP-0512009-A4 (EP)
Title: Temperature-sensing control system and method for integrated circuits
IPC: G05D23/20
Filed: 1990-11-26
Abstract: A temperature-control system includes an integrated circuit (14) and a sequence controller (12) therefore, wherein the sequence controller (12) provides instructions and/or data to the integrated circuit (14) which performs operations according to the instructions on the data. A temperature recognition intervention mechanism is provided which intervenes, via the sequence controller (12), with the operational rate of the integrated circuit (14) in relation to different temperature conditions which occur in the integrated circuit (14), thus providing security against temperature-induced damage to the integrated circuit (14). A method of the invention includes detecting a temperature-related parameter of the integrated circuit (14), determining the rate of change of the temperature (76) of the integrated circuit (14) and, if the rate of change indicates that the integrated circuit (14) will exceed a first predetermined temperature, providing noop (82) instructions to the integrated circuit (14) for a predetermined number of system cycles to allow the integrated circuit (14) to cool to an acceptable temperature. If the rate of change of the temperature indicates that the integrated circuit (14) will reach a temperature higher than a second predetermined temperature value, the frequency of noop instructions will increase or the integrated circuit (14) will be shut down (86).
Patent EP-0516701-A4 (EP)
Title: Video telephone system
IPC: H04N21/2368
Filed: 1991-02-14
Abstract: Apparatus and method are provided for the simultaneous transmission of video information and audio information in substantially real time over an ordinary voice grade telephone line having limited bandwidth in the range of about 300-3400 Hz. Because of the limited bandwidth of the ordinary telephone line, the video and audio information are compressed before transmission thereof. Each of the video information and audio information is separately compressed, mixed together and then further compressed. After the further compression, a composite signal, which includes the mixture of video and audio information, is asynchronously transmitted over the same bandwidth of the ordinary telephone line. Upon reception, the compressed information is expanded and separate video information and audio information are reproduced for viewing and hearing by the receiving party. To reduce the size of the apparatus, application specific integrated circuits (ASICs) are employed. A state machine controller apparatus is integrated with the ASIC technology to control the transfer and storing of video information and audio information and also to control the operation of the various compression and expansion stages associated with the transmitting and receiving channels.
Patent EP-0548086-A4 (EP)
Title: Method and dispersants for production of high solids aqueous calcium carbonate suspensions.
Inventor: BROWN ALAN J
IPC: C09K23/00
Filed: 1991-06-25
Abstract: A method for producing a high solids aqueous slurry of particulate calcium carbonate having highly stable aging characteristics, comprising dispersing in water at at least 70% by weight solids, a finely divided particulate calcium carbonate, utilizing as a dispersing agent from 20 to 34 lbs/ton of dry mineral (expressed as 40% actives), of a copolymer of acrylic acid and a sulfonated vinyl monomer, which is converted to the salt form by from about 30 to 50% of its carboxylic acid sites being neutralized with a polyvalent cation, and substantially the balance of said carboxylic sites being neutralized with a monovalent cation.
Patent EP-0502144-A4 (EP)
IPC: B62D63/06
Filed: 1991-08-13
Abstract: Remorque légère (18) à une seule roue prévue pour le remorquage àl'arrière d'une bicyclette, comprenant un réceptacle s'ouvrant vers le haut réalisé en fils entrecroisés, monté à l'avant de la roue arrière de la remorque. Ladite remorque est démontable. Le réceptacle peut se détacher de la remorque et on peut le plier pour obtenir ainsi un stockage et un transport économiques. La partie arrière (24) de la remorque peut se détacher de la partie avant (22) et elle comprend des bras latéraux se projetant vers l'arrière entre les extrémités arrière (52) desquelles la roue arrière (56) de la remorque est tourillonnée. L'extrémité avant de la remorque comprend un ensemble d'attelage qui assure son couplage à l'extrémité avant de la tige verticale supportant la selle d'une bicyclette associée.
Patent EP-0572417-A4 (EP)
Title: Nucleic acid amplification by two-enzyme, self-sustained sequence replication.
Inventor: FAHY EOIN DAVID
IPC: C12Q1/68
Filed: 1991-11-13
Abstract: Novel methods are provided for nucleic acid amplification by continuous, substantially isothermal, self-sustained sequence replication ("3SR") utilizing RNA-dependent DNA polymerase activity, DNA-dependent DNA polymerase activity, RNAse H activity and DNA-dependent RNA polymerase activity. In one of the methods, before enzymatic activities can be provided by only two enzymes, a reverse transcriptase and a DNA-dependent RNA polymerase. The methods may employ two or three enzymes to provide the necessary enzymatic activities. Thus, in certain of the methods, an exogenous source of RNAse H, such as E. coli RNAse H, is employed in combination with a reverse transcriptase and a DNA-dependent RNA polymerase. In other of the methods of the present invention, reaction media are employed in which the inherent RNAse H activity of retroviral reverse transcriptases is effective to provide high levels of amplification so that only two enzymes, reverse transcriptase and DNA-dependent RNA polymerase, are required. Novel compositions for carrying out the methods of the present invention are also provided.
Patent EP-0595995-A4 (EP)
Title: Arylamidoalkyl-n-hydroxyurea compounds having lipoxygenase inhibitory activity
Inventor: DELLARIA JOSEPH F
IPC: C07D213/65
Filed: 1992-07-07
Abstract: PCT No. PCT/US92/05715 Sec. 371 Date Jan. 10, 1994 Sec. 102(e) Date Jan. 10, 1994 PCT Filed Jul. 7, 1992 PCT Pub. No. WO93/02037 PCT Pub. Date Feb. 4, 1993.The present invention provides certain (substituted carbocyclic aryl)amidoalkyl- and (substituted heterocyclic aryl)amidoalkyl-N-Hydroxy urea compounds which inhibit lipoxygenase enzyme activity and are thus useful in the treatment of allergic and inflammatory disease states.
Patent EP-0599941-A4 (EP)
Title: Fluid strainer convertable between motorized and manual modes.
Inventor: SIMONELLI JAMES K
IPC: B01D29/11
Filed: 1992-08-06
Abstract: An improved fluid-strainer is provided which makes provision for improved methods of converting the same between motorized and manual modes. Included in the fluid strainer is a gear motor housing for facilitating the conversion as well as inspection and removal means. Also provision is made for flushing of the fluid strainer so as to avoid cycle restart.
Patent EP-0704046-A4 (EP)
Title: Lensmeter with guided lens movement for progressive addition lens
Inventor: HUMPHREY WILLIAM E
IPC: G02C7/06
Filed: 1993-07-13
Abstract: A computer indicated lens movement direction protocol is utilized in combination with a lensmeter to designate required movement of lenses with respect to a lensmeter to insure sequential measurement of progressive addition lenses. Lens measurement occurs at four sample points closely spaced on the lens surface. The system uses power variations (PV1 and PV2) at each of the spaced apart lens sampling points to indicate when sampling of the lens occurs in a region of constant spherical power, when sampling of the lens occurs in a region of changing spherical power, and finally when sampling again occurs in a region of constant and increased spherical power. When sampling of the lens occurs in a region of changing power, lens movement is guided along a path of constantly changing sphere utilizing changes in astigmastim measured in the 45  - 135  directions (Cx). A lens examination protocol is set forth with vector indicators setting forth the vertical direction required for movement as well as both desired left and right movement to maintain the shortest possible path between the respective lens portions.
Patent EP-0672133-A4 (EP)
Title: TNF--g(a) RIBOZYMES AND DEGRADATION RESISTANT mRNA DERIVATIVES LINKED TO TNF--g(a) RIBOZYMES.
Inventor: SIOUD MOULDY
IPC: C12N15/09
Filed: 1993-11-03
Abstract: This invention describes compounds active against TNF- alpha  mRNA. It further describes mRNA molecules capable of conferring stability to RNA in vivo. Possible mRNA molecules to be stabilized include ribozymes, antisense molecules and mRNA encoding polypeptides useful for protein production. The ribozymes and antisense molecules described herein are useful in mammals and plants, particularly suited for viral diseases. Methods of production and methods of use are also described.
Patent EP-0764048-A4 (EP)
Title: Chromatography adsorbents utilizing mercapto heterocyclic ligands
Inventor: SCHWARZ ALEXANDER
IPC: C07K16/00
Filed: 1995-05-16
Abstract: A pseudobioaffinity chromatography adsorbent adapted for use in selectively adsorbing immunoglobulins. In one embodiment, the adsorbent includes: (a) a solid support material; and (b) a ligand immobilized on the surface of the solid support material, said ligand being a compound of the formulawherein Y1 is selected from the group consisting of S, SCH3+, O, NH, NCH3, CH2 and CR1R2 wherein at least one of R1 and R2 is not hydrogen; wherein each of Y2, Y3 and Y4 is selected from the group consisting of N, NCH3+, CH, and CR wherein R is not hydrogen; and wherein at least two of Y1, Y2, Y3 and Y4 are neither CH2, CH, CR nor CR1R2.
Patent EP-0826436-A4 (EP)
Title: Ultra-thin sheet steel and method for manufacturing the same
Inventor: ARATANI MAKOTO
IPC: B21B15/00
Filed: 1997-03-14
Abstract: A method for manufacturing an ultra-thin sheet steel comprising the steps of roughly rolling a steel billet into a sheet bar, but joining the sheet bar so rolled to a preceding sheet bar, heating widthwise edge portions of the sheet bars so joined by means of edge heaters, continuously cross rolling joined bars by means of paired cross rolls at least at three stands for finishing to produce a hot rolled steel strip having a sheet width of 950 mm or greater, a sheet thickness of 0.5-2 mm and a crown of ± 40 νm or less, cold rolling, continuously annealing and temper rolling the hot rolled steel strip, and plating the surface of a cold rolled steel strip as required to produce a sheet steel having an average sheet thickness of 0.20 mm or less, a sheet width of 950 mm or greater, and a sheet thickness variation in a sheet width direction of ± 4 % of the average sheet thickness and a hardness (HR30T) variation in the sheet width direction of ± 3 or less of the average hardness in a range not less than 95 % of a sheet width.
Patent EP-0894002-A4 (EP)
Title: Novel peptides which inhibit complement activation
Inventor: LAMBRIS JOHN D
IPC: C07K7/64
Filed: 1997-03-11
Abstract: Peptides capable of inhibiting complement activation are provided. Methods of inhibiting complement activation and complement-mediated tissue injury using these peptides are also provided. In addition, a method of producing compositions capable of inhibiting complement activation using these peptides is provided, along with the peptide analogs and peptidomimetics produced by the method.
Patent EP-0971677-A4 (EP)
Title: Bone cement and method of preparation
Inventor: LAUTENSCHLAGER EUGENE P
IPC: A61K6/884
Filed: 1997-11-26
Abstract: Orthopedic bone cements of low porosity, prepared by mixing together at least two liquid components under conditions that allow only minimal exposure to air, are disclosed. In a preferred system, each liquid component consists essentially of a solution of a linear (non-crosslinked) polymer or copolymer of methyl methacrylate (PMMA) dissolved in a non-crosslinking methyl methacrylate (MMA) monomer, with one such solution also containing an activator and a polymerization inhibitor and a second solution containing an initiator as well as a polymerization inhibitor. No reinforcing fillers are present, although a small amount (no more than 12% by weight of the total cement composition) of a radiopacifier may be included in the composition. Since polymerization is initiated by mixing together two or more liquid solutions, and such mixing may be performed in a mixing chamber in which no air is required or is introduced during the mixing operation, prior problems of cement porosity and weakness resulting from air entrapment are avoided or greatly reduced while the reliability and reproducibility of the mixing operation are greatly improved.
Patent EP-1009558-A4 (EP)
Title: Joining metal components
Inventor: SIMMONS ANTHONY GRANT
IPC: B21D53/26
Filed: 1998-04-17
Abstract: This invention concerns a method of joining forged, machined, formed or cast components with a metal tube. In another aspect, it concerns a metal object constructed according to the method. The tube is heated to expand its diameter, but not sufficiently to anneal it, or otherwise adversely affect its mechanical properties. Then, while the tube is still hot, it is pushed over part of the central component so that part of the tube overlies a circumferential groove in the central component. Then, while still hot, the circumferential part of the tube which overlies the groove, is rolled into the groove, so that when cooled the rolled part of the tube is clamped into the groove. The invention is particularly, but not exclusively, applicable to the construction of vehicle wheels having a forged, machined, formed or cast hub or center and a metal rim.
Patent EP-0992241-A4 (EP)
Title: Medicinal compositions against helicobacter pylori
Inventor: WATANABE MASATO
IPC: C07D215/60
Filed: 1998-05-14
Abstract: An anti-Helicobacter pylori pharmaceutical composition containing a 1-hydroxy-3-methyl-quinolone derivative represented by the following formula (I) <CHEM> or a pharmaceutically acceptable salt thereof as an active ingredient. Since it shows antibacterial action upon Helicobacter pylori, this invention is effective for the treatment or prevention of infection with Helicobacter pylori in human and infection with related bacteria belonging to the genus Helicobacter in animals. Also, the anti-Helicobacter pylori pharmaceutical composition of the present invention is useful for the prevention (including prevention of relapse) or treatment of diseases of the upper digestive organs, such as peptic ulcers (e.g., gastric and duodenal ulcers), inflammations (e.g., acute or chronic gastritis or duodenitis) and gastric cancer, as well as MALT (mucosa-associated lymphoid tissue) lymphoma or chronic heart diseases.