baber/WOPTO huggingface dataset:
Patent AU-2004217817-A1 (AU)
Title: Animal model for the fast identification of pharmaceutical active compounds in vivo
Inventor: BELIEN ANN TRUDO JOSEE
IPC: C12Q1/68
Filed: 2004-03-03
Abstract: In a first aspect the present invention provides a tumor cell line stably transfected with an expression vector containing a reporter gene, preferably a fluorescent protein, operably linked to a promotor that also controls expression of a protein that is associated with tumor regression, stabilization of tumor growth or inhibition of metastatic growth, characterized in that said cell line is capable to form a tumor when implanted or injected into the non-human animal. Compared to the traditional in vivo models, the present invention differs in that the reporter gene is not constitutively expressed, but only after exposure to a test compound that results in the expression of a protein or enzyme associated with tumor regression, stabilization of tumor growth or inhibition of metastatic growth. Only when a compound to be tested got into circulation and infiltrated the tumor it may generate the reporter signal, provided it promotes the expression of a protein associated with tumor regression and the promoter of said protein is operably linked to the reporter gene.
Patent AU-2004228596-A1 (AU)
Title: Method in production of packaging laminate
Inventor: ZUO GUANGJU
IPC: B65D65/40
Filed: 2004-03-17
Abstract: Method in connection with the continuous joining of a first layer (10, 38) of a first material and a second layer (16, 40) of a second material, to produce a packaging laminate (44, 48) comprising said first and second layers. According to the invention, a free surface of said first layer (10, 38) and/or a free surface of said second layer (16, 40) is subjected both to plasma treatment (24) and to flame treatment (20), where after said free surfaces are joined together (12, 14). The invention relates also to a packaging laminate thus produced and to a packaging container manufactured from such a packaging laminate.
Patent AU-2004266070-A1 (AU)
Title: Pharmaceutical composition comprising a combination of metformin and a statin
Inventor: JUNIEN JEAN-LOUIS
IPC: A61K31/404
Filed: 2004-08-20
Abstract: A pharmaceutical composition comprising: (i) metformin, optionally in the form of one of its pharmaceutically acceptable salts, (ii) a statin, optionally in the form one of its pharmaceutically acceptable salts, and optionally one or more pharmaceutically acceptable excipients, is suitable for use in the treatment of hyperglycemia non-insulin-dependent diabetes, dyslipidemia, hyperlipidemia, hypercholesterolemia, and obesity.
Patent AU-2004270231-A1 (AU)
Title: Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis
Inventor: CALHOUN JASON
IPC: A61K31/65
Filed: 2004-09-07
Abstract: The present invention is directed to a method for treating bone or bone marrow infections, joint infection or infection of the tissues surrounding the joint by administration of the antibiotic tigecycline alone or in combination with a rifamycin antibiotic. In a preferred embodiment the bone or bone marrow infection causes osteomyelitis. In another embodiment the joint infection or infection of the tissues surrounding the joint causes septic arthritis. The invention is also directed to manufacture of a medicament for treatment of bone and/or bone marrow infections, or joint infections and/or infections in tissues surrounding the joint with tigecycline alone or in combination with rifampin.
Patent AU-2004303425-A1 (AU)
Title: Pharmaceutical compositions
Inventor: KAZAKEVICH IRINA
IPC: A61K9/00
Filed: 2004-12-17
Abstract: Disclosed are useful pharmaceutical compositions.
Patent AU-2004303629-A1 (AU)
Title: Methods for detection of Mycobacterium tuberculosis
Inventor: SHARMA PAWAN
IPC: C12Q1/68
Filed: 2004-12-22
Abstract: The present invention provides an oligonucleotide primer pair having SEQ ID NO: 3 and SEQ ID NO: 4 for amplification of Early Secretory Antigenic Target (esat)-6-gene of Mycobacterium species. The invention also provides a method for detecting M .tuberculosis in a sample based on the amplification of esat-6 gene, comprising isolating DNA template from the sample, amplifying with the above oligonucleotide primer pair and subjecting the amplified DNA product to separation and staining to detect the presence of amplified DNA product for identifying Mycobacterium tuberculosis in the sample. The invention further provides a diagnostic kit for detection of Mycobacterium tuberculosis. The invention also provides a method of detecting Mycobacterium tuberculosis from a sample by amplifying the 16s rRNA region from the isolated DNA template by conventional methods to detect Mycobacterium species and further amplifying the positive sample contains Mycobacterium species using primers positive for ESAT-6 region detection of Mycobacterium tuberculosis.
Patent WO-2005077473-A1 (WO)
Title: Appareil d'exercice physique
Inventor: ROSS BRUCE WILLIAM
IPC: A63B23/04
Filed: 2005-02-18
Abstract: Appareil d'exercice physique (10) possédant un cadre principal (11) présentant une partie avant (15) et une partie arrière (16), une partie verticale (17) éloignée de la partie avant (15) et un chariot mobile (12) coulissant par rapport à la partie avant (15) du cadre principal (11). Un câble (14) est accouplé par une de ses extrémités au chariot (12) et s'étend depuis la partie avant (15) jusqu'à la partie verticale (17). Un poids (13) est monté pivotant sur la partie verticale (17), accouplé à l'autre extrémité du câble (14) et placé au-dessus de la base du cadre principal en arrière de la partie avant (17), de sorte qu'une force exercée sur le chariot (12) provoque l'élévation du poids (14), ce qui créé une résistance contre la force s'exerçant sur le chariot (12).
Patent WO-2006007658-A1 (WO)
Title: Element de structure et procede de formation d'un element de structure
Inventor: ELLEN MURRAY
Filed: 2005-07-21
Abstract: La présente invention concerne un élément de structure (10) qui comprend un élément allongé creux externe (12) formé d'un matériau peu fragile et un élément creux interne (14) formé d'un matériau peu fragile qui se situe dans l'élément creux externe (12) auquel il est soudé. L'élément creux interne (14) et l'élément creux externe sont reliés l'un à l'autre alors qu'ils se trouvent sous tension ou comprimés l'un par rapport à l'autre.
Patent AU-2005234717-A1 (AU)
Title: Bone shaping instrument and method for using the same
Inventor: BENNETT TRAVIS
IPC: A61B17/16
Filed: 2005-11-21
Abstract: A bone resection tool for resecting an end of a bone along a surface having a curvature comprises a guide (10), a cutting tool (100,200) and a track follower (110). The guide is configured to be removably attached in a fixed position to the end of the bone. The guide is configured to include a track (58) exhibiting a curvature generally corresponding to the curvature of the surface to be resected in the bone. The cutting tool includes a cutting face. The track follower is configured to couple to the cutting tool and cooperate with the track to facilitate reciprocation of the cutting tool relative to the guide to induce the cutting face to resect the bone along the surface having the curvature.
Patent AU-2005235957-A1 (AU)
Title: 2-alkylidene-18,19-dinor-vitamin D compounds
Inventor: DELUCA HECTOR F
IPC: C07C401/00
Filed: 2005-02-04
Abstract: 2-alkylidene-18,19-dinor-vitamin D compounds are disclosed as well as pharmaceutical uses for these compounds and methods of synthesizing these compounds. These compounds are characterized by low bone calcium mobilization activity and high intestinal calcium transport activity. This results in novel therapeutic agents for the treatment and prophylaxis of diseases where bone formation is desired, particularly osteoporosis, as well as autoimmune diseases such as multiple sclerosis, diabetes mellitus and lupus. These compounds also exhibit pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis. These compounds also increase both breaking strength and crushing strength of bones evidencing use in conjunction with bone replacement surgery such as hip and knee replacements.
Patent AU-2005237660-A1 (AU)
Title: VFFS/HFFS packaging with opening aid on the longitudinal seam and process of making such a packaging
Inventor: DAELMANS EDDY
IPC: B65B9/20
Filed: 2005-02-17
Abstract: The present invention is related to a VFFS/HFFS packaging comprising a plastic film, a longitudinal seam (2) and a cross-directional seam (5), wherein the longitudinal seam (2) comprises a substantially continuous teeth structure (1) representing tear initiations over the whole length of the longitudinal seam to enable easy opening of said packaging. <??>The present invention is also related to a process of making such a packaging, said process starting out from a reel comprising a continuous teeth structure on its lateral edges. <IMAGE>
Patent AU-2005296848-A1 (AU)
Title: Moulding material for the production of fire-retarding objects, pigment therefor and use thereof
Inventor: FIBLA VINCENS MANS
IPC: C09K21/14
Filed: 2005-10-14
Abstract: A moulding material for the production of highly flame resistant articles with a matrix of a thermoplastic and a particulate pigment dispersed therein is characterized in that the pigment is light-sensitive and changes colour under the influence of laser light and in that the pigment is a reaction product of at least one halogen-free flame retardant organic nitrogen base with (i) at least one mixed salt with at least two different cations and/or with (ii) a mixture of salt type compounds which on heating can be transformed into at least one salt type compound with at least two different cations, as in (i); wherein in variations (i) and (ii), at least one of the cations is selected from a group (A) of elements Ti, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Nb, Mo, Ag, Sn, Sb, La, Pr, Ta, W and Ce and at least one further cation is selected from a group (B) of elements from periods 3 and 6 of groups II and III, periods 5 and 6 of group IV and periods 4 and 5 of groups III to VIII and the lanthanides of the periodic table of the elements.
Patent AU-2005308023-A1 (AU)
Title: L-amino acid-producing bacterium and a method for producing L-amino acid
Inventor: NAKAMURA JUN
IPC: C12P13/06
Filed: 2005-11-25
Abstract: Coryneform bacteria are described that have an ability to produce L-amino acids and are modified so that acetyl-CoA hydrolase activity is decreased. The bacteria are used to produce L-amino acids generated by a biosynthetic pathway in which pyruvic acid is an intermediate, such as L-glutamic acid, L-arginine, L-glutamine, L-proline, L-alanine, L-valine, and L-lysine.
Patent AU-2005331946-A1 (AU)
Title: Multi-hull watercraft with amidships-mounted propellers
Inventor: SCHMIDT TERRENCE W
IPC: B63H5/08
Filed: 2005-06-29
Abstract: An efficient double-ended watercraft is disclosed that comprises four low-Froude number hulls: two forward, two aft, two on the port side, and two on the starboard. Each hull comprises an independent engine that drives a propeller shaft and propeller that is located amidships. The propeller shafts on the starboard are collinear, as are the propeller shafts on the port. The propellers on the starboard are near each other and counter rotate, as do the propellers on the port. The propellers are variable-pitch propellers. When the ferry is changes from moving forward to moving in reverse and from reverse to forward, the propellers on the starboard exchange pitch. This enables the ferry to move as efficiently in reverse as it does when forward. The propellers on the port also exchange pitch when changing from moving forward to moving in reverse and from reverse to forward.
Patent AU-2006235486-A1 (AU)
Title: Polymorphs of 3-o-(3',3'-dimethylsuccinyl) betulinic acid di-N-methyl-D-glucamine
Inventor: HAUSHERR ARNDT
IPC: A61K31/704
Filed: 2006-04-12
Abstract: The present invention relates to crystalline polymorphs of 3-O-(3′,3′-dimethylsuccinyl)betulinic acid di-N-methyl-D-glucamine salt (“DSB•2NMG)”), pharmaceutical compositions of the same and use of the same as an active pharmaceutical agent in the treatment of HIV related disorders.
Patent AU-2006322099-A1 (AU)
Title: Cutting element for a retracting needle syringe
Inventor: SWENSON JON
IPC: A61M5/00
Filed: 2006-12-04
Abstract: A cutting element for a retracting needle syringe having a plunger with a cuttable distal end and a spring biased needle held by a cuttable support and a cutting element capable of cutting the cuttable distal end and the cuttable support includes a body portion having a proximal end, a distal end side wall therebetween and a passageway therethrough. The distal end of the body portion includes a cutting edge and a raised distally projecting tapered cutting tooth having distally converging edges. At least one tooth edge includes a sharp side wall for cutting the distal end of the plunger and the needle support.
Patent AU-2006334743-A1 (AU)
Title: Substituted imidazoline derivatives
Inventor: OBERBORSCH STEFAN
IPC: C07D233/28
Filed: 2006-12-19
Abstract: Imidazoline derivatives (I) are new. Imidazoline derivatives of formula (I) and their isomers and salts are new. n : 0-2; R 1>(un)saturated 1-8C alkyl, (un)saturated 3-8C cycloalkyl, aryl(1-3C)alkyl or heteroaryl(1-3C)alkyl, all optionally substituted; R 2>aryl, heteroaryl or aryl(1-3C)alkyl, all optionally substituted; R 3>(un)saturated 1-8C alkyl or aryl(1-3C)alkyl, both optionally substituted; R 4>H, 1-4C alkyl or aryl(1-3C)alkyl; R 5>, R 6>H or optionally substituted (un)saturated 1-8C alkyl, but not both H, or R 5>+R 6> is CH 2CH 2OCH 2CH 2 or (CH 2) m; m : 3-6. Independent claims are also included for: (1) a process for preparing (I); (2) aldehydes of formula B. [Image] [Image] ACTIVITY : Analgesic; Antidepressant; Uropathic; Antidiarrheic; Antipruritic; Antialcoholic; Antiaddictive; Tranquilizer. MECHANISM OF ACTION : mu -Opiate receptor inhibitor. Methyl 1-cyclohexyl-5-(4-(dimethylamino(3-fluorophenyl)methyl)-4-isobutyl-4,5-dihydro-1H-imidazole-4-carboxylate gave 84% inhibition of human mu -opiate receptor activity at a concentration of 1 mu M.
Patent WO-2008040061-A1 (WO)
Title: Séquences de promoteurs d'acide nucléique contrôlant l'expression génique des plantes
Inventor: HENRY ROBERT J
IPC: C12N5/04
Filed: 2007-10-04
Abstract: L'invention concerne une séquence d'acide nucléique isolée comprenant une séquence nucléotidique qui correspond à une région à activité de promoteur d'une séquence d'ADN, la séquence d'acide nucléique isolée étant issue d'une semence de céréale. Les séquences d'acide nucléique isolées sont utiles pour le contrôle de taux élevés de d'expression génique à l'intérieur de tissus spécifiques d'une semence de céréale. L'invention porte également sur des produits de construction génétiques comprenant les séquences d'acide nucléique isolées (et des variantes de celles-ci) liées de façon fonctionnelle à une séquence transcrivable, sur des procédés de fabrication d'une protéine recombinante utilisant lesdits produits de construction génétiques, et sur des procédés pour faciliter l'expression cible à un endosperme de plante.
Patent WO-2008109912-A1 (WO)
Title: Protocoles de turbocodage et de relais distribués
Inventor: LI YONGHUI
IPC: H04L29/06
Filed: 2007-11-09
Abstract: Cette invention concerne des protocoles de turbocodage et de relais distribués dans des réseaux de relais sans fil. En particulier, l'invention concerne un procédé permettant de relayer des signaux au niveau d'un nœud de relais, un procédé permettant de traiter les signaux au niveau d'un nœud de destination, un système de relais et un logiciel pour effectuer les procédés. Les réseaux de relais sans fil comprennent un nœud de source, un nœud de destination et un ou plusieurs nœuds de relais. Au niveau d'un nœud de relais, l'invention comprend les étapes consistant à recevoir un signal d'un premier nœud ; décoder le signal reçu ; et si le signal reçu est décodé de façon incorrecte, utiliser un protocole de relais par amplification et transfert (AAF) comprenant les étapes consistant à amplifier le signal reçu puis à transmettre le signal amplifié à un second nœud ; mais autrement, employer un protocole de relais par Décodage et transfert (DAF) comprenant les étapes consistant à recoder le signal décodé puis à transmettre le signal codé au second nœud. Au niveau d'un nœud de destination, les données transmises par le nœud source sont récupérées par combinaison de tous les signaux reçus à partir des nœuds sources et de relais puis décodage du signal combiné.
Patent AU-2007210152-A1 (AU)
Title: Fluidic droplet coalescence
Inventor: AHN KEUNHO
IPC: B01J19/00
Filed: 2007-01-24
Abstract: The present invention relates to a method, comprising: 
providing a microfluidic system comprising one or more channels (25,28,29); 
providing within said one or more channels (25,28,29) a first fluidic stream and a second fluidic stream, at least one of which comprises droplets that have an average diameter of less than about 450 microns and that are highly monodisperse; and applying an electric field (40) simultaneously to at least a portion of the first fluidic stream and a portion of the second fluidic stream such that said portions coalesce.
Patent AU-2007312905-A1 (AU)
Title: System and method for deactivating IP sessions of lower priority
Inventor: KIM JIN
IPC: H04W48/08
Filed: 2007-10-10
Abstract: Systems and Methods are provided for deactivating IP sessions of lower priority. There may be instances when a mobile device moves from a first area supporting a plurality of IP sessions to a second area supporting fewer IP sessions. In this situation, if the mobile device has more IP sessions than is supported by the second area, then the wireless network will deactivate IP sessions. According to an embodiment of the application, the mobile device determines a respective priority for each of the II' M sessions and transmits an indication of each respective priority to the wireless network. According to another embodiment of the application, the wireless network deactivates II' sessions that are indicated to be of lower priority. Accordingly, IP sessions that are not deactivated are those indicated by the mobile device to be of greater priority.
Patent AU-2007337798-A1 (AU)
Title: Roller assembly for web material dispenser
Inventor: MOLLER PER
IPC: A47K10/36
Filed: 2007-12-21
Abstract: A roller assembly in a wipe material dispenser has at least one pair of cooperating rollers arranged to feed the wipe material. The roller assembly comprises a first and a second roller, wherein each roller comprises a central longitudinal core on which is mounted a number of parallel and axially spaced discs. Each roller has regions of reduced diameter between adjacent discs, and the first and the second roller are located so that the axial location of the spaced discs on the first roller coincides with the regions of reduced diameter between adjacent discs on the second roller. A roller suitable for use in the roller assembly and a dispenser including such an assembly are also provided.
Patent WO-2008089521-A1 (WO)
Title: Insulin sensitisers and methods of treatment
Inventor: COLLIER GREGORY ROYCE
IPC: A61K31/433
Filed: 2008-01-25
Abstract: The present invention relates generally to the field of therapy. The invention particularly relates to insulin sensitisers and methods of regulating glucose homeostasis and to the therapeutic or prophylactic treatment of diseases and associated conditions, in which impaired glucose uptake due to insulin resistance is involved or implicated, such as diabetes, syndrome X, hyperglycaemia, vascular disease and kidney disease. The present invention further relates to compounds and agents and compositions thereof for use in the treatment methods.
Patent WO-2009079695-A1 (WO)
Title: Appareil d'imagerie médicale amélioré
Inventor: NIEMIEC ANDREW
IPC: A61B8/00
Filed: 2008-12-19
Abstract: La présente invention concerne un appareil d'imagerie médicale par ultrasons qui comprend une unité de commande et une sonde, la sonde comprenant au moins une unité de transducteur qui contient un transducteur à ultrasons, l'unité de transducteur étant attachée de manière amovible à la sonde.
Patent AU-2008322964-A1 (AU)
Title: Method for producing a thickener dispersion
Inventor: SCHMIDT KATI
IPC: C08F220/18
Filed: 2008-11-13
Abstract: A method is described for producing an aqueous thickener dispersion from a monomer composition made of at least one ethylenically unsaturated carboxylic acid and at least one ethylenically unsaturated hydrophobic monomer, (i) an at least partially polymerized pre-emulsion being produced from 10 to 80 wt.-% of said monomer composition, and (ii) the residual quantity of said monomer composition being added completely to the at least partially polymerized pre-emulsion and initiating a radical polymerization. The monomer composition preferably also comprises an associative monomer. The method avoids disadvantages of batch polymerization, such as inadequate batch-to-batch reproducibility and safety problems.
Patent AU-2009200247-A1 (AU)
Title: Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
Inventor: HEIL WOLFGANG
IPC: A61K31/567
Filed: 2009-01-22
Abstract: The present invention relates to a multiple-phase pharmaceutical preparation consisting of a number of separately packaged and individually removable daily dosage units placed in a packaging unit and intended for oral administration for a period of at least 21 consecutive days, wherein said daily dosage unit comprises a natural estrogen, such as estradiol in an amount of from 0.5 mg to 4 mg, and 2 to 4 mg of drospirenone, and wherein at least 70% of said drospirenone is dissolved from said dosage unit within 30 minutes, as determined by USP XXIII Paddle Method II using water at 37°C as the dissolution media and 50 rpm as the stirring rate.
Patent WO-2010105297-A1 (WO)
Title: Verrou pour bagage
Inventor: ANDREI CRISTIAN
IPC: E05B65/52
Filed: 2010-03-18
Abstract: L'invention concerne un dispositif de verrouillage (100) comprenant un ou plusieurs bras mobiles (104) dotés d'une ou de plusieurs parties (112) configuré pour venir en prise avec des anneaux (140) sur un ou plusieurs éléments de fermeture (128) d'une fermeture éclair (130). Lorsqu'il est attaché à l'élément ou aux éléments de fermeture (128), le dispositif de verrouillage (100) est placé généralement dans le plan de la fermeture éclair ou parallèlement à celui-ci et ne s'étend sensiblement pas au-dessus du plan général de la fermeture éclair et le dispositif de verrouillage (100) est configuré pour permettre à l'élément ou aux éléments de fermeture (128) de venir en prise avec le dispositif de verrouillage (100) et d'être libéré de celui-ci, tandis que le dispositif de verrouillage (100) est placé généralement dans le plan de la fermeture éclair ou parallèlement à celui-ci.
Patent WO-2011020160-A1 (WO)
Title: Aube pour eolienne
Inventor: HESSAMODINI AZAD
IPC: F03D11/04
Filed: 2010-08-20
Abstract: L'invention concerne une éolienne qui a un axe autour duquel, à l'emploi, l'aube tourne. L'aube est disposée pour orientation le long de l'axe et présente une torsion longitudinale. L'aube comprend une partie aube interne et une partie aube externe. A l'emploi, la partie aube interne est plus proche de l'axe que la partie aube externe. La partie aube externe présente une orientation angulaire qui varie par rapport à la partie aube interne dans une direction le long de l'axe.
Patent AU-2010203698-A1 (AU)
Title: Targeted antimicrobial moieties
Inventor: ECKERT RANDAL H
IPC: A61K38/08
Filed: 2010-01-06
Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.