baber/WOPTO huggingface dataset:
Patent EA-201990570-A1 (EA)
Title: Моноклональное антитело против pd1, его фармацевтическая композиция и их применение
IPC: G01N33/68
Filed: 2017-08-22
Abstract: Моноклональное антитело против PD1 (белок 1 запрограммированной клеточной смерти) или его антигенсвязывающий фрагмент, его фармацевтическая композиция и их применение. Вариабельная область тяжелой цепи моноклонального антитела содержит CDR (область, определяющая комплементарность) с аминокислотными последовательностями, указанными в SEQ ID NO: 9-11; и/или вариабельная область легкой цепи моноклонального антитела содержит CDR с аминокислотными последовательностями, указанными в SEQ ID NO: 12-14. Моноклональное антитело может специфически связываться с PD1, ослаблять иммуносупрессию PD1 в организме и активировать T-лимфоциты.
Patent EA-201991070-A1 (EA)
Title: Связывающие молекулы, специфичные в отношении asct2, и их применения
IPC: G01N33/574
Filed: 2017-11-08
Abstract: В данном раскрытии предложены ASCT2-связывающие молекулы, например, антитела к ASCT2, и их антиген-связывающие фрагменты. В некоторых аспектах ASCT2-связывающие молекулы конъюгированы с цитотоксическими лекарственными средствами, например, конъюгатами антитела к ASCT2 и лекарственного средства (ADC). В определенных аспектах антитела к ASCT2 и их фрагменты могут представлять собой полученные с помощью гибридомной технологии мышиные моноклональные антитела и их гуманизированные варианты. В определенных аспектах ASCT2-связывающие молекулы специфично связываются с клетками, экспрессирующими ASCT2, и в некоторых случаях - поглощаются клетками. Кроме того, в данном раскрытии предложены композиции и способы для диагностирования и лечения заболеваний или расстройств, характеризующихся сверхэкспрессией ASCT2, например, определенных типов онкологических заболеваний. В определенном варианте осуществления в данном раскрытии предложены способы лечения онкологического заболевания с использованием ASCT2 ADC.
Patent EA-202090997-A1 (EA)
Title: Усовершенствованная подводная промысловая система
IPC: A01K79/02
Filed: 2018-11-22
Abstract: Настоящее изобретение относится к промысловой системе для промысла зоопланктона или мезопелагической рыбы и способу промысла зоопланктона или мезопелагической рыбы.
Patent EA-202091894-A1 (EA)
Title: Применение 5-фтор-4-(4-фтор-2-метоксифенил)-n-{4-[(s-метилсульфонимидоил)метил]пиридин-2-ил}пиридин-2-амина для лечения диффузной в-крупноклеточной лимфомы
IPC: C07D213/72
Filed: 2019-02-12
Abstract: Изобретение относится к применению 5-фтор-4-(4-фтор-2-метоксифенил)-N-{4-[(S-метилсульфонимидоил)метил]пиридин-2-ил}пиридин-2-амина (соединение A), более предпочтительно (+)5-фтор-4-(4-фтор-2-метоксифенил)-N-{4-[(S-метилсульфонимидоил)метил]пиридин-2-ил}пиридин-2-амина (соединение A'), для лечения диффузной В-крупноклеточной лимфомы (DLBCL), в особенности для диффузной В-крупноклеточной лимфомы из В-клеток зародышевого центра и в особенности для диффузной В-крупноклеточной лимфомы, клетки которой имеют амплификацию или транслокацию гена MYC и/или гена BCL2 и/или сверхэкспрессию MYC и/или BCL2.
Patent EA-202191681-A1 (EA)
Title: Коллоидная дисперсная система, подходящая для инверсии фаз, для стимуляции скважин для добычи углеводородов
Filed: 2019-12-18
Abstract: Изобретение относится к коллоидной композиции для стимуляции скважин для добычи природного газа или нефти с высоким водопритоком, которая при смешивании с водой образует структурированный высоковязкий барьер для ограничения водопритока и снижения объемного соотношения воды и углеводородов; кроме того, во время использования вблизи от скважин остаточная нефть, адсорбированная на поверхности углеводородного пласта-коллектора, и/или остаточная нефть, защемленная в порах углеводородного пласта-коллектора, становится сжимаемой и извлекаемой. Коллоидная композиция содержит соединение, основанное на продукте реакции растительного масла. Эксперименты с новой композицией продемонстрировали, что ее можно успешно применять при значительно более широком диапазоне параметров, чем ранее, для получения барьера, приводящего к ограничению водопритока, а также для мобилизации и извлечения остаточной нефти, сцепленной с поверхностью скважины.
Patent EA-202192391-A1 (EA)
Title: Продукт для ухода за полостью рта
Filed: 2020-02-27
Abstract: Изобретение относится к продукту для ухода за полостью рта, такому как жидкость для полоскания рта, пародонтальный гель или зубная паста, содержащему хлоргексидин и ДНК натрия. Указанный продукт для ухода за полостью рта обладает антибактериальным действием, эффективным против гингивита, бактериального налета и пародонтита, в сочетании с заживляющей и противовоспалительной активностью, и который, кроме того, противодействует окислительному стрессу, таким образом ограничивает начало и прогрессирование раздражений слизистой оболочки полости рта и способствует их трофике.
Patent ES-2169666-A1 (ES)
Title: Grinding machine with direct drive rotary wheelhead
Inventor: LUIS VIZCAINO ELIAS
IPC: B23Q17/22
Filed: 2000-05-17
Abstract: A grinding machine with a wheelhead (1) with direct drive rotation capability, said grinding machine having a motor (2) to generate the rotary movement that enables the wheelhead (1) to turn in respect of a fixed support shaft (8), and an encoder (3) to detect the angular position of the wheelhead (1). Both the motor (2) and the encoder (3) are housed in the wheelhead (1), said motor (2) being high torque. The rotor (2a) of the motor (2) is attached to the support shaft (8) and the wheelhead (1) is attached to the stator (2b) of said motor (2).
Patent ES-2168072-A1 (ES)
Title: Clamp with a tightening screw
Inventor: PALAU DOMINGUEZ RAMON
IPC: F16L33/04
Filed: 2000-07-14
Abstract: Improved clamp with a tightening screw consisting of a coiled metal strip and ends, the head of a transversal screw being located on one end of said strip and a nut for the end of said screw being located on the other end of the strip, in addition to a lower hinged part to fill the space between the two ends of the strip. The center of said metal strip (1) forming the clamp has a protruding nerve (3) on the inner surface reaching close to the heads on both ends of the strip and the edge of each short side of the hinged bridge part has two U-shaped perpendicular central notches (10 and 11) to enable penetration of the central nerve (3) into said notches.
Patent ES-2188408-A1 (ES)
Title: System for the prediction of radiation emitted by an item of electronic equipment.
Inventor: RODRIGUEZ SECO JOSE EMILIO
IPC: G01R31/00
Filed: 2001-10-30
Abstract: Simulated measuring system for emitted radiation in accordance with a standard EMI test for an item of screened electronic equipment with apertures and emerging cables, in which the equipment to be measured is configured, indicating the physical parameters of its volume and the cables connected to it the value of the electric field X is measured (in V/m) in the said aperture and the value of the current Y (in A) in the said cable, and is calculated from the equations:EMAX (dB[mu]V/m) = 20 Log [X/(1V/m)] + [K1 + k2fMHz + k3.Log(fMHz)<2>].yEMAX (dB[mu]V/m) = 20 Log [Y/lA)] + [K1 + k2fMHz + k3.Log(fMHz)<2>]Which based on known data of the value of the field (X) and intensity (Y) and the constants (k1), (k2) and (k3) determines the maximum value of the electric field (EMAX)X produced by each opening and the maximum value of the electric field (EMAX)Y produced by each cable for each value of the frequency (f).For application in the electronics industry.
Patent ES-2239900-A1 (ES)
Title: Recuperation of hydrochloric acid from spent metal pickling baths comprises addition of sulfuric acid, producing iron and zinc sulfates, and also zinc by addition of solvent
Inventor: TUSET MENDEZ SERGIO
IPC: C01B7/01
Filed: 2004-03-22
Abstract: The recuperation of hydrochloric acid from spent metal pickling baths comprises t he addition of sulfuric acid to the bath, to produce iron and zinc sulfates and hydrochloric acid. Cooling of the resulting solution to ca. 0[deg]C precipitates ferrous sulfate heptahydrate by crystallization. Then, after vacuum evaporation, further cooling of the concentrate to ambient temperature solidifies the zinc sulfate and some of the ferrous sulfate. The zinc can also be separated by addition of solvent trapping the zinc salts.
Patent ES-2249977-A1 (ES)
Title: Anchor mechanism for door and window gunner, has core that has orifice for receiving conical nuts, support formed in T shape, wheel cover cylinder, and piston rod arranged crossing disc orifice situated between gunners
Inventor: RAMIREZ SEGUNDO FELIX
IPC: E05B1/00
Filed: 2004-03-24
Abstract: The mechanism has a core located inside each gunner of a door or window. The core has an orifice for receiving conical nuts, a support formed in T shape, and wheel cover cylinder. A piston rod is arranged crossing a disc orifice situated between the gunners. A ring or wheel cover has a threaded end screwed to the conical nut, and another end with an internal spiral graft for adjusting the piston rod. A double-ended stud is provided crossing the perforation of an inner support to couple with a fixed nut.
Patent ES-2267364-A1 (ES)
Title: Modulation circuit for reducing harmonics of interference in power converters has reduction circuitry whose operation depends on modulation of frequency of commutation signal
Inventor: GAGO BARRIO JAVIER
IPC: H03L7/00
Filed: 2004-11-23
Abstract: An integrated circuit (IC) in a commutation system of a power converter selectively reduces harmonics of commutation frequency that causes interference in the supply lines of the power converter. A reduction circuitry operates based on the modulation in the frequency of a commutation signal.
Patent ES-2259898-A1 (ES)
Title: Automated system and method for examining the transport properties of fluids in porous materials
Inventor: MARTIN CALLEJA JOAQUIN
IPC: G05D9/12
Filed: 2004-12-22
Abstract: The invention relates to the development of an instrument system and a method that can be used to obtain measurements relating to the transport properties of fluids in porous materials. The inventive system comprises a fully-automated, computer-controlled system which is used to obtain the aforementioned measurements in a continuous manner. The automation of the system provides a solution to the sources of errors encountered in standard methodologies which are used to obtain said type of measurements and which are derived from an almost-artisan work method. The main components of the system comprise: a thermostating subsystem (1), a sample chamber (2), a subsystem through which the interaction fluid flows (3), an electronic control subsystem (4), a sample support assembly (5), a weighing assembly (6) and a computerised measurement and control subsystem (7).
Patent ES-2291067-A1 (ES)
Title: Rehabilitation and consolidation method for boxes at low voltage electrical distribution, involves closing all water entrance, application of epoxy resins and carbon fiber by sealing with covering of surfaces
Inventor: ANTON FERRERES RAMON
IPC: H02B1/26
Filed: 2005-04-06
Abstract: The rehabilitation and consolidation method involves closing all water entrance, application of epoxy resins and carbon fiber by sealing with covering of the surfaces affected by a continuous layer with mineral silicates.
Patent ES-2267399-A1 (ES)
Title: Method of obtaining phenyl carbamates
Inventor: MURILLO GARRIDO JOSE VICENTE
IPC: C07C215/50
Filed: 2005-08-04
Abstract: The invention relates to a method of obtaining phenyl carbamates (I), wherein R 1 is lower alkyl C 1 -C 5 or benzyl and R 2 is methyl, ethyl or propyl, consisting in reacting L-(S)-3-[(1-methylamino)ethyl]phenol, in the presence of a base, with a carbamoyl halide in order to obtain an intermediate and, subsequently, subjecting said intermediate to a reducing amination reaction or a methylation reaction by reacting same with a methyl halide. The above-mentioned compounds (I) include rivastigmine, a compound that inhibits cholinesterase in the central nervous system, and can be used in the treatment of neurodegenerative diseases (E.g. senile dementia and Alzheimer's disease).
Patent ES-2277540-A1 (ES)
Title: Securing device for support for bookcases has fixation unit having projection that is formed by folding lamina and through stamping process
Inventor: CATALA MASDEU JORDI
IPC: A47B57/40
Filed: 2005-10-25
Abstract: A metallic body is laminated on a flat base having a fixation unit for a support and one prolongation with two ascending or flat faced transversal fins. The fixation unit includes a projection descending relative to the base and located in a zone next to the metallic body. The projection is formed by folding lamina and through a stamping process. An independent claim is included for a positioning method in a support.
Patent ES-2285926-A1 (ES)
Title: System and method for processing units of value
Inventor: EBERHARDT JENS
IPC: G06Q40/00
Filed: 2004-06-28
Abstract: The invention relates to a system and method for processing units of value, such as banknotes, coins or checks. A system and method for processing deposits of units of value and provided in which banknotes of the deposit are examined one after another in two banknote processing machines, and the data of both the first as well as of the second examining process are fed to an evaluation device in order to carry out an evaluation of the deposit based on both the first as well as second examining process. This two-step processing creates the ability to carry out the processing of deposits in cash centers in a significantly more efficient manner than with methods used up to now.
Patent ES-2288121-A1 (ES)
Title: Method of functioning of aerogenerator
Inventor: NIM ERIK
IPC: G01S17/95
Filed: 2006-05-31
Abstract: Operation method for a variable speed wind turbine which comprises control methods for blade pitch in cases of extreme gusts of wind, characterised by the fact that it is comprised of the following steps: a) detection of the presence of an extreme gust of wind b) performance of a sudden increase in pitch within the range of 6 to 14 degrees at the maximum speed permitted by the wind turbine blade pitch control mechanisms. The method also includes an additional step c) vary the generator speed to avoid an increased acceleration of the generator which could make a subsequent step b) necessary.
Patent ES-2292360-A1 (ES)
Title: Power generator has two or more sets same and different, isolated, rotating, synchronized and interconnected such that once operated generate more energy
Inventor: DOS SANTOS ALTINO
IPC: H02N1/08
Filed: 2006-08-24
Abstract: The power generator has two or more sets same and different, isolated, rotating, synchronized and interconnected such that once operated generate more energy.
Patent ES-2293840-A1 (ES)
Title: Machine for cutting and extracting the stem of vegetables having a tree-like structure and cutting and extraction method carried out with said machine
Inventor: COMIN ESCARTIN RICARDO
IPC: A23N15/00
Filed: 2006-09-07
Abstract: This invention refers to a machine for the cutting and extraction of the stem of vegetables with tree-like structure and the cutting and extraction method of the stem with this machine which provides pieces branched into different sizes of the edible part of the vegetable. The machines is characterized by being constituted by at least one tray in which the vegetable to be cut is deposited which slides along a horizontal structure and by several vertical slide guides with several cutting devices for the separation of the useful tree-like material, a cutting device for the division of the stem into pieces and a cutting device for the separation of the stem from the edible part. It can be additionally equipped with knives arranged radially on the cutting head for the division of the tree-like material into portions.
Patent ES-2304209-A1 (ES)
Title: System and method of pneumatic suspensions for lifting apparatus and lifting apparatus comprising said system
Inventor: SAGARTZAZU SORAZU XABIER
IPC: B66B11/02
Filed: 2006-12-14
Abstract: System and method of pneumatic suspension for lifting apparatus and lifting apparatus comprising said system, enabling the adaptation of the suspension features of a cabin (1) of a lifting apparatus with respect to a chassis (3) of said cabin (1) depending on the load conditions and/or functioning of the lifting apparatus, wherein the system includes a number of pneumatic springs (7) located between the cabin (1) and the chassis (3), each pneumatic spring (7) with at least one chamber (9) by means of a conduit (8) which has a valve (10) configured to control the flow of a compressible gas contained in said pneumatic spring (7) and said chamber (9), such that the rigidity and damping capacity of each pneumatic spring (7) is controlled, insulating the cabin (1) from unwanted vibrations, in accordance with the conditions of the lifting apparatus at each moment.
Patent ES-2362604-A1 (ES)
Title: Topical ophthalmic peptide formulation
Inventor: PONSATI OBIOLS BERTA
IPC: A61K9/08
Filed: 2009-12-22
Abstract: Topical ophthalmic formulation of peptides and their use for the treatment and/or local prevention of ocular diseases, preferably posterior segment eye diseases.
Patent ES-2376737-A1 (ES)
Title: Real-time location method at area level of radio frequency-transmitting portable devices
Inventor: MONTON SANCHEZ EDUARDO
IPC: H04W4/00
Filed: 2010-04-22
Abstract: REAL-TIME LOCATION METHOD AT AREA LEVEL OF RADIO FREQUENCY-TRANSMITTING PORTABLE DEVICES, through bracelets provided with a RF transmitter, comprising a network of fixed radio frequency receivers (2), allowing the core system (3) the reception of the signals it contemplates the utilization of other nodes (4) of the network, using the adaptation of IP addresses to radio frequency frames and the association of devices for creating radio frequency networks on TCP/IP networks. With the power received in the fixed receivers (2) it defines, through an algorithm, the distance between receiver and transmitter, and the area in which the transmitter is present. In order to optimize the transmission of information, it utilizes a 16 or 24 bits network identifier achievable by any other receiver in the TCP/IP network.
Patent ES-2490940-A1 (ES)
Title: Method and template with geometric features for calibrating and checking measurements with articulated arms for measuring using coordinates
Inventor: CUESTA GONZALEZ EDUARDO
IPC: G01B5/008
Filed: 2013-03-04
Abstract: The invention concerns a method and template with geometric features for checking and calibrating measurements with articulated arms for measuring using coordinates, which comprises solid spheres, virtual spheres, planes, inner cylinders (44), (45) and outer cylinders (42), (43), (58), (59) and inner cones (48), (49) or outer cones. The invention concerns a particular selection and spatial arrangement of geometric features which enable numerous geometric and dimensional tolerances to be produced. The measuring of the geometric features and comparison thereof with reference values in different spatial positions enable both the measuring technique and apparatus to be evaluated, such that operatives can be trained or accredited with respect to their use. The invention also concerns a method for calibrating and verifying by means of this template. The invention can be applied in sectors in which calibration templates are designed, produced and used, such as industrial dimensional metrology preferably with portable or fixed machines which measure using coordinates.
Patent JO-P20170182-A1 (JO)
Title: Method for cleaning air conditioner indoor unit and outdoor unit
Inventor: WU HONGJIN
Filed: 2017-10-26
Abstract: The present invention discloses a method for cleaning an air conditioner indoor unit and outdoor unit. The method includes: controlling a to-be-cleaned heat exchanger to enter a self-cleaning mode; adjusting an operating frequency of an air conditioner, an opening of a throttling device, and a corresponding fan speed of the to-be-cleaned heat exchanger, and maintaining an evaporating temperature of the to-be-cleaned heat exchanger within a present range, so as to enable a surface of the to-be-cleaned heat exchanger to frost; keeping the to-be-cleaned heat exchanger frosting for a time of t1; detecting whether a differential pressure between a high pressure and a low pressure of the air conditioner meets a preset condition; when the differential pressure between the high pressure and the low pressure of the air conditioner meets the preset condition, controlling a four-way valve to change a direction, so as to perform a defrosting switching to indoor and outdoor heat exchangers; and when the differential pressure between the high pressure and the low pressure of the air conditioner does not meet the preset condition, adjusting an operating parameter of the air conditioner to enable the differential pressure between the high pressure and the low pressure of the air conditioner to meet the preset condition, and then controlling the four-way valve to change the direction, so as to perform a defrosting switching to the indoor and outdoor heat exchangers. A direction change of the four-way valve may be controlled by detecting whether the differential pressure between the high pressure and the low pressure of the air conditioner meets the preset condition. Therefore, a great shock to the compressor because of an excessive differential pressure between the high pressure and the low pressure of the air conditioner may be avoided.
Patent SG-78417-A1 (SG)
Title: Method of pipe welding
Inventor: NICHOLSON PETER
IPC: B23K31/02
Filed: 2000-07-18
Abstract: A method of welding the ends of two pipes at the open root between the spaced ends by an STT electric arc welder, which comprises: selecting a welding wire having .06 - .15% by weight carbon, .90 - 1.40% by weight manganese, and .45 - .75% by weight silicon, as well as phosphorous, copper, stainless steel alloys and sulfur; maintaining the sulfur at a given percentage level of the selected wire in the specific range of .015 to .035% by weight; and maintaining said phosphorous at a given percentage level of said selected wire in the specific range of less than about .015%.
Patent SG-115493-A1 (SG)
Title: Control of gene expression
IPC: C12N15/82
Filed: 1999-03-19
Abstract: The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.
Patent SG-112001-A1 (SG)
Title: Telecommunications services apparatus
Inventor: WILSON JEFFREY
IPC: H04L12/58
Filed: 2003-10-10
Abstract: The attribute of the received message is compared with the message attribute stored in the storage to select opt message application. The selected message is executed to route, process and transform the respective message. Independent claims are also included for the following: (1) telecommunication service method; (2) telecommunication service program; and (3) computer readable medium storing telecommunication service program.
Patent SG-128470-A1 (SG)
Title: A modular printhead assembly with thermal distortion compensation
Inventor: KIA SILVERBROOK
IPC: B41J2/00
Filed: 2001-03-09
Abstract: A printhead assembly for an inkjet printer includes a support beam. A plurality of printhead modules is fast with a portion of the support beam. Each printhead module includes a printhead chip. The printhead modules are positioned so that the printhead chips are aligned with each other. Said portion of the support beam and the printhead chips are primarily of materials having substantially the same coefficient of thermal expansion.