baber/WOPTO huggingface dataset:
Patent DK-231083-D0 (DK)
Inventor: BAKER JOSEFINA TECSON
IPC: G01N33/72
Filed: 1983-05-24
Abstract: A method and novel absorbent substrate for determining the presence of occult blood in gastric fluid. The substrate is acid treated and contains guaiac. The method includes the addition of the gastric fluid to the acid treated guaiac substrate which is developed with a buffered developing solution. Preferably the substrate is an acid treated sheet of absorbent paper and the developing solution is an aqueous buffered solution of hydrogen peroxide.
Patent DK-312989-D0 (DK)
Inventor: STOLTEFUSS JUERGEN
IPC: C07C335/00
Filed: 1989-06-23
Abstract: The invention relates to compounds of the general formulae (II) <IMAGE>  in which     A represents hydrogen or methyl, and B represents a group of the formula -NH, -NH-CO-, -NH-CS-, -NH-COO-, -NH-SO2- or -NH-CO-NH- or -NH-CS-NH-,   D represents oxygen or the group =NH, and   D' represents hydroxyl or the group NH2, and E represents hydrogen or, in the case of (IIa), represents hydrogen or the group =CHR<1>. By acylating the corresponding threonine derivatives by means of diketene and using the intermediates II for the preparation of the threonyl esters of 3,5-dicarboxy-1,4-dihydropyridine.
Patent DK-392686-D0 (DK)
Inventor: PETER HEINRICH
IPC: A61K31/265
Filed: 1986-08-18
Abstract: PCT No. PCT/CH85/00175 Sec. 371 Date Aug. 11, 1986 Sec. 102(e) Date Aug. 11, 1986 PCT Filed Dec. 13, 1985 PCT Pub. No. WO86/03747 PCT Pub. Date Jul. 3, 1986.N- and/or O-acylates, derived from carbonic acid monoesters, of desferrioxamine B of the formula   <IMAGE> (I) <IMAGE>  the symbols having the following meanings: each of AA1, AA2 and AA3, independently of the others, is hydrogen, an acyl radical, referred to as Ac, of a carboxylic acid having from 1 to 24 carbon atoms, or an esterified oxycarbonyl radical referred to as Cb (acyl radical of a carbonic acid monoester) having a total of from 2 to 25 carbon atoms, and B has one of the meanings of Cb or, if at least one of the symbols AA1, AA2 and AA3 represents Cb, it may also be hydrogen or an amino-protecting group referred to as X, form strong iron (III) and aluminum complexes within living cells and can therefore be used therapeutically for the treatment of warm-blooded animals, including humans, for pathological conditions associated with an excess of iron (III) or aluminum in the body or caused by iron (III)-dependent pathogenic organisms; they can also be used as intermediates for the manufacture of therapeutically effective derivatives of desferrioxamine B. The compounds according to the invention can be obtained by conventional acylation of the free amino group and/or hydroxy groups in desferrioxamine B or a suitable derivative thereof using a chloroformic ester or a similar reactive carbonic acid derivative.
Patent DK-393486-D0 (DK)
Inventor: WIKEL JAMES HOWARD
IPC: C07D409/04
Filed: 1986-08-19
Abstract: The invention discloses the use as vasodilators of compounds of the formula 
<CHEM>
 wherein:
 R1 is hydrogen, C1-C4 alkyl, or 
<CHEM>
 each R2 is independently hydrogen, methyl, or amino;
 each R3 is independently hydrogen, -COR7, -CO2R7, or -S(O)nR7;
 R4 is hydrogen, methyl, methoxy, halo, nitro, or amino;
 R5 is hydrogen, methyl, methoxy, halo, C1-C4 alkylthio;
 R6 is hydrogen, halo, C1-C4 alkoxy, C1-C4 alkyl, or nitro;
 m is 0, 1, 2, 3, or 4;
 Z is O, S, or NH;
 three or four of A1, A2, A3, and A4 are CH, and the remaining of A1, A2, A3, and A4, if any, is N;
 R7 is -alk-(Y-alk-)t-R8, allyl, propargyl, C3-C6 cycloalkyl, phenyl, or phenyl substituted with one to three substituents selected from C1-C4 alkyl, C1-C4 alkoxy, nitro, or halo;
 each "alk" is a divalent organic radical derived from a C1-C6 aliphatic hydrocarbon;
 Y is -O-, -NH-, or a bond;
 t is 0 or 1;
 R8 is hydrogen, phenyl, pyridyl, -CN, or -NR9R10;
 n is 0, 1, or 2; and
 R9 and R10 are independently C1-C3 alkyl or benzyl, or when taken together with the nitrogen atom to which they are attached form a pyrrolidino, piperidino, or homopiperidino ring, or a pharmaceutically acceptable salt thereof. Certain of the compounds are novel.
Patent DK-423089-D0 (DK)
Inventor: BIRATH BJOERN
IPC: B31B50/62
Filed: 1989-08-28
Abstract: Method and apparatus for applying glue on separate lids (6) and sealingly introducing said lids (6) in containers (18), especially by means of a fully automatic apparatus comprising a supplier (1) for lids (6) or lid panels, a rotor (8) or carousel useful for multi-stage handling of lids (6), or lid panels or lid frames having a reclosing lid rotatably connected thereto, and received from the lid supplier (1), and a supplier (4) of packages or containers tubes (18) co-operating with said rotor (8), and in which the lid handling rotor (8) comprises one or more lid catchers (10-13) which can be expelled from and be retracted into the rotor (8) for catching a lid (6) from the lid supplier (1), and for pressing lids (8) into the open end of a container presented by the container supplier (4), and which can also rotate about a shaft which is radial in relation to the rotor (8), whereby glue or an equivalent adhering substance is applied to the edge of the lid or the lid panel by means of a stationary glue application means (3).
Patent DK-430583-D0 (DK)
Inventor: TSUKAMOTO KYOZO
IPC: C12P21/04
Filed: 1983-09-21
Abstract: The invention relates to novel polypeptide of the formula <IMAGE> wherein X is a bond, or a peptide or amino acid residue 1 to 16 amino acids counting from the C terminus of the peptide chain of   <IMAGE> and Y is a peptide or amino acid residue having 1 to 5 amino acids counting from the N terminus of the peptide chain of <IMAGE> and conjugate between the same and a carrier protein, as well as hybridoma and monoclonal antibody derived by the use of the polypeptide or the conjugate, and a method of detecting and of purifying human gamma-interferon using the antibodies.
Patent DK-442285-D0 (DK)
Inventor: KALVODA JAROSLAV
IPC: C07D499/88
Filed: 1985-09-30
Abstract: (4R)-3,4-trans-disubstituted azetidinones of the formula <IMAGE> in which R1 denotes hydrogen or lower alkyl, R2 denotes hydrogen or a hydroxyl-protecting group R, R3 denotes phenyl, substituted phenyl or lower alkyl and R4 denotes hydrogen or an amino-protecting group R, are valuable intermediates for the preparation of optically active penem or carbapenem compounds which act as antibiotics. The processes comprise the ring closure between carbon atoms 3 and 4 of the azetidinone ring.
Patent DK-447786-D0 (DK)
Inventor: GRAU ULRICH
IPC: C07K1/113
Filed: 1986-09-18
Abstract: PCT No. PCT/EP86/00008 Sec. 371 Date Sep. 2, 1986 Sec. 102(e) Date Sep. 2, 1986 PCT Filed Jan. 11, 1986 PCT Pub. No. WO86/04335 PCT Pub. Date Jul. 31, 1986.A process for the preparation of insulin precursors of the formula (I)   <IMAGE> (I)  in which R is hydrogen or the presequence Pm-Qn-, in which P is a sequence of naturally occurring amino acids with m being from 0 to 50, Q are basic natural amino acids, and n is an integer from 1 to 4, Y represents -LysB29-ZB30-, in which Z denotes Ala, Thr or Ser, and the bridge extending from A-1 to A-21 is an insulin A-chain, the bridge extending from B-1 to B-30 represents an insulin B-chain, and X is a bridge which is bonded to the insulin A-chain at the amino group of A-1 and is bonded to the insulin B-chain at the  epsilon -amino group of B-29- in which case it is bonded to the free bond of ZB30OH- or at the carboxyl group of B-30, from reaction mixtures which result from folding of insulin precursors from S-sulfonates of the formula (II) <IMAGE> (II)   in which R, X and Y have the abovementioned meanings, which comprises the false recombinants contained in the reaction mixture being precipitated by adjustment of the reaction mixture to pH 4 to 6, the precipitate being removed in customary manner and converted by sulfitolysis into the S-sulfonate of the formula (II), and the latter then being subjected to renewed folding.
Patent DK-595589-D0 (DK)
Inventor: HVARRE JOHN NIKOLAJ
IPC: C02F1/48
Filed: 1989-11-27
Abstract: A mouthpiece (1) for a water tapping point, for example a water tap (2) or similar installation, has a row of flow modifying elements (6-12) so arranged as to impart to the outflowing water jet (5) a desired, preferably quietly regulated, non-splashing state of flow. At least one of these flow modifiying elements (7) is made wholely or partly of magnetic material on e.g. a ceramic basis, so that the flow channels of the mouthpiece (1) are automatically kept free of incrustation.
Patent DK-710188-D0 (DK)
Inventor: BEKELE SOLOMON
IPC: B32B7/06
Filed: 1988-12-20
Abstract: Disclosed is a film (1) for forming vacuum skin packages which comprises a coextruded, multi-layer composite forming web comprising a gas permeable film (2) and a gas impermeable film (3) which can be manually delaminated from each other, the gas permeable film having a plurality of layers including a heat sealable, polymeric layer, and a layer comprising a linear ethylene/alpha-olefin copolymer having a density of less than 0.915 g/cc, the gas impermeable film having a plurality of layers including a barrier layer of a hydrolyzed ethylene/vinyl-acetate or vinylidene chloride copolymer the barrier layer being immediately adjacent to and in contact with the linear ethylene/alpha-olefin copolymer so that when the layers are peeled apart the barrier layer will become a first surface layer and, an outer or second surface layer of polymeric material: the heat sealable layer of the permeable film seals to the surface of the package support member with a bond strength greater than the force required to delaminate the permeable layer from the impermeable layer so that the permeable layer can be peeled from the impermeable layer leaving the package covered with a permeable layer so that oxygen can penetrate to the packaged product.
Patent HU-902141-D0 (HU)
Title: Process and apparatus for modification the positions of sevaral elements placed along one line relative to each other
Inventor: SAUVINET VINCENT
IPC: B05B15/68
Filed: 1990-04-10
Abstract: The invention relates to a procedure and a device for modifying the relative positions of a plurality of parts aligned along a first configuration in such a way as to arrange them, in line, along a second configuration. 
<??>The procedure consists (a) in selectively coupling at least one of the parts (1) to a shuttle (5) which is movable parallel to the alignment of parts, (b) in moving the shuttle up to a defined position, (c) in decoupling the shuttle from the part after its installation at the defined position and (d) in repeating the stages (a), (b) and (c) for all the parts to be moved. 
<??>Application to the remote setting of injectors of pulverulent products with a view to the formation, on a substrate which is moving past, of a layer having particular properties. 
<IMAGE>
Patent HU-905134-D0 (HU)
Title: Molecular antibodies for the indication of tolerance
Inventor: COBBOLD STEPHEN PAUL
IPC: C12P21/02
Filed: 1990-05-31
Abstract: Tolerance to an antigen is induced in a subject by administering a non-depleting CD4 monoclonal antibody and a non-depleting CD8 monoclonal antibody. Tolerance to the antigen can be induced under cover of these antibodies. A depleting CD4 monoclonal antibody and/or a depleting CD8 monoclonal antibody may be administered prior to the non-depleting antibodies.
Patent NO-862973-D0 (NO)
Inventor: WALKER MICHAEL MONTGOMERY
IPC: A61K6/884
Filed: 1986-07-24
Abstract: An improved orthopedic or dental implant is formed so that at least its bone contacting surfaces are comprised of a biocompatible organic polymer substituted with salt-forming sulfur oxyacid groups or biocompatible salts thereof. In addition, a method of promoting bone tissue deposition and adhesion has been found which utilizes an implant having a biocompatible organic polymer substituted with carbon, sulfur or phosphorous oxyacid groups or sales thereof on its bone contacting surfaces. Such oxyacid substituted polymers have been found to promote interfacial osteogenesis, to enhance the rate of bony growth into porous implant surfaces, and to foster direct chemical bonding of the implant surface with the biological polymers present in developing bone tissue.
Patent NO-865107-D0 (NO)
Inventor: ELING BEREND
IPC: C08G18/16
Filed: 1986-12-17
Abstract: The invention relates to the preparation of polymer foams containing urethane and isocyanurate linkages by the use of a catalyst system based on an alkali metal or tetraalkylammonium carboxylate and a group IIa metal carboxylate.
Patent NO-871567-D0 (NO)
Inventor: PABST MICHAEL
IPC: H01H9/10
Filed: 1987-04-14
Abstract: The invention relates to a manually-operated circuit breaker (1) having a two-armed switch lever (9) supported such that it can pivot on the switch housing. Its drive arm (24) together with a push rod (11) form the guide of a bell crank (25) in kinematic drive terms. A contact link (13) connects two fixed contacts (14, 15). The pivoting movement of the switch lever produces a follow-through movement of the bell crank (25) through its extended position against a contact spring pressure, which allows the contact link (13) to be transferred into a contact open position, and vice versa. The push rod (11) is inserted such that it can pivot with an end remote from the contact (guide end 26) in a guide slot (27) running in its pivoting direction on the unsupported end of the drive arm (24) of the switch lever (9), and such that it can move in the slot direction. Between its ends, the push rod is provided with a latching tab (34) which, after a follow- through movement of the push rod (11) in the contact open direction, through the bell crank extended position under the contact spring force of the contact link (13) in the open position, is located in a stop position on a latch projection (35) fixed to the housing and holds the contact link (13) in the contact open position.   <IMAGE>
Patent NO-902597-D0 (NO)
Inventor: GASTALDELLO GIANCARLO
IPC: B29C43/22
Filed: 1990-06-12
Abstract: The present invention relates to an improved tread assembly, for retreading motor vehicle tires, characterized in that said assembly comprises a shaped tread body,having a concave face, which has a profile mating with the surface of the tire carcass, and a substantially convex face having a balance profile equal to the balance profile of the tread of a new tire.
Patent NO-931977-D0 (NO)
Inventor: SCHALLY ANDREW V
IPC: A61K38/08
Filed: 1993-05-28
Abstract: The novel pseudo polypeptides of this invention are potent bombesin antagonists. There are provided processes for their production, pharmaceutical compositions comprising said polypeptides and their use as pharmaceutically active agents. More particularly the present invention provides pseudopeptides comprising a nonapeptide moiety of formula I: X-A1-A2-A3-A4-A5-A6-A7-A8-psi-A9-Q wherein Q is NH2 or OQ1 where Q1 is hydrogen, C1-10 alkyl, phenyl or phenyl-C7-10alkyl; X is hydrogen or a single bond linking to A2 the acyl residue of an organic acid, or a group of formula R1CO- wherein (1) R1 is hydrogen, C1-10 alkyl, phenyl or phenyl-C7-10-alkyl; (2) R1CO- is (a) R2N(R3)-CO- wherein R2 is hydrogen, C1-10alkyl, phenyl or C7-10phenyl-C7-10-alkyl, R3 is hydrogen or C1-10alkyl; (b) R4-O-CO- wherein R4 is C1-10alkyl, phenyl or phenyl-C7-10-alkyl. A1 is D-, L- or DL- pGlu,, Nal, Phe, Thl, Tyr, Tpi, Hca, Hpp, Mpp, Trp or Trp substituted in the benzene ring by one or more members selected from the group consisting of halogen, NO2, NH2, OH, C1-3 alkyl and C1-3 alkoxy wherein halogen is fluorine, chlorine and bromine; wherein A2-A7 and A9 are each amino acid residues; A8 is a reduced isostere of Leu or Phe.
Patent NO-933139-D0 (NO)
Inventor: LUNDGREN DAN
IPC: A61L27/18
Filed: 1993-09-03
Abstract: PCT No. PCT/SE92/00139 Sec. 371 Date Sep. 3, 1993 Sec. 102(e) Date Sep. 3, 1993 PCT Filed Mar. 4, 1992 PCT Pub. No. WO92/15340 PCT Pub. Date Sep. 17, 1992.This invention relates to a bioresorbable material and an article of manufacture of such material for medical use comprising homopolymers, copolymers, or a blend thereof selected from the group of monomers including glycolic acid, lactic acid, caprolactone, trimethylene carbonate, paradioxanone and 1,5 dioxepan-2-one, a plasticizer selected from the group including ethyl, butyl and hexyl esters of acetylated or non-acetylated citric acid, ethyl terminated oligomers of lactic acid, having no less than 2 and no more than 10 units, and lactic acid esters of glycerol, the material comprises 50% of amorphous polymer or polymers to impart to the material plastic malleability substantially without memory.
Patent NO-934248-D0 (NO)
Inventor: ANGERER ERWIN VON
IPC: C07D333/56
Filed: 1993-11-24
Abstract: Novel furans and thiophenes of the general formula I <IMAGE>  are described, in which R<1> and R<2> independently of one another denote a hydrogen atom, an alkyl group having 1 to 10 carbon atoms, a benzyl group, a group C(O)R<4>, where R<4> is an alkyl or alkoxy group having 1 to 10 carbon atoms or a phenyl radical, or a carbamoyl group -C(O)NR<5>R<6>, where R<5> and R<6> independently of one another are a hydrogen atom or an alkyl group having 1 to 10 carbon atoms, and n denotes an integer from 0 to 12 when R<3> is a hydrogen atom or n denotes an integer from 4 to 12 when R<3> is an amino group -NR<7>R<8>, where R<7> and R<8> independently of one another represent a hydrogen atom or an alkyl group having 1 to 10 carbon atoms or R<7>-R<8> together represent an alkylene group -(CH2)m- or the group -(CH2)2O(CH2)2- or R<3> denotes an amide group -C(O)NR<7>R<8>, where R<7> and R<8> have the abovementioned meanings, or R<3> denotes a sulphinyl group -S(O)R<9>, where R<9> is the radical -(CH2)m(CF2)oCF3 and m and o are 2, 3, 4, 5 or 6 and  X is an oxygen or sulphur atom. The novel compounds have potent and selective antioestrogenic activity and are suitable for the treatment of oestrogen-dependent diseases.
Patent NO-934586-D0 (NO)
Inventor: PEARSON TIMOTHY B
IPC: B65B13/18
Filed: 1993-12-13
Abstract: A mechanism for use with a strapping machine comprising a strapping head, means for advancing a strap fed into the strapping head, means for sensing whether a leading end of the strap being advanced has reached a predetermined location within a predetermined time, and means for retracting the strap. The mechanism comprises means for severing the strap being fed into the strapping head into a leading portion including the leading end and a trailing portion if the sensing means has not sensed that the leading end has reached the predetermined location within the predetermined time and means adapted to coact with the retracting means for ejecting the leading portion after the strap has been severed. <IMAGE>
Patent NO-944071-D0 (NO)
Inventor: JANOFF ANDREW S
IPC: A61K/
Filed: 1994-10-26
Abstract: Methods and compositions are described for nonliposomal lipid complexes in association with toxic hydrophobic drugs such as the polyene antibiotic amphotericin B. Lipid compositions are preferably a combination of the phospholipids dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylglycerol (DMPG) in about a 7:3 mole ratio. The lipid complexes contain a bioactive agent, and may be made by a number of procedures, at high drug:lipid ratios. These compositions of high drug:lipid complexes (HDLCs) may be administered to mammals such as humans for the treatment of infections, with substantially equivalent or greater efficacy and reduced drug toxicities as compared to the drugs in their free form. Also disclosed is a novel liposome-loading procedure, which may also be used in the formation of the HDLCs.
Patent NO-953359-D0 (NO)
Inventor: BLACKER ANDREW JOHN
IPC: C07D303/04
Filed: 1995-08-25
Abstract: PCT No. PCT/GB94/00307 Sec. 371 Date Aug. 25, 1995 Sec. 102(e) Date Aug. 25, 1995 PCT Filed Feb. 26, 1994 PCT Pub. No. WO94/19338 PCT Pub. Date Sep. 1, 1994Described herein is a process for the preparation of (1S,2R)-1,2-epoxy-1,2,3,4-tetrahydronaphthalene having the Formula (I):    <IMAGE>  Formula (I)  which comprises the steps of (a) hydrogenating the compound of Formula (II) to form cis-(1R, 2S)-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene having the Formula (V):   <IMAGE>   (b) reacting the dihydroxy compound of Formula (V) with a sulphonyl halide of formula R1SO2Z wherein R1 is methyl, ethyl, trifluoromethyl, phenyl or p-tolyl, and Z is fluorine, chlorine, bromine or iodine to give a bis-sulphonyl ester of formula (X):   <IMAGE>   and (c) treating the bis-sulphonyl ester (X) with an alkali metal carbonate or alkali metal hydroxide to give the compound of Formula (I).
Patent NO-963556-D0 (NO)
Inventor: NODA ISAO
IPC: D04H1/42
Filed: 1996-08-26
Abstract: The present invention comprises processes for preparing biodegradable fibrils from one or more biodegradable homopolymeric or copolymeric resins, said process comprising: a) forming a liquid resin mixture by melting or solvating the resin or resins; and b) introducing the liquid resin mixture to a flow of a gaseous substance. The present invention further comprises biodegradable fibrils made according to the processes of the present invention. The invention further comprises nonwoven fabrics comprising biodegradable fibrils. The invention further comprises disposable absorbent articles comprising a water-permeable topsheet, an absorbent core, and a water-impermeable backsheet, wherein the topsheet comprises a nonwoven substrate comprising biodegradable fibrils. The invention further comprises disposable articles comprising biodegradable fibrils.
Patent NO-972123-D0 (NO)
Inventor: POSTI HARRI
IPC: H04W36/12
Filed: 1997-05-07
Abstract: PCT No. PCT/FI95/00610 Sec. 371 Date May 9, 1997 Sec. 102(e) Date May 9, 1997 PCT Filed Nov. 8, 1995 PCT Pub. No. WO96/15637 PCT Pub. Date May 23, 1996A method for performing encoding in a cellular network includes, in each cell, at least one base station communicating with terminal equipment within its coverage area, and a mobile switching center controlling the operation of the base stations. In order to improve the transmission quality over a connection between two terminal equipment, when the mobile switching center detects, during call set-up or handover, that the call is between two terminal equipment located within the area of the mobile switching center, the mobile switching center guides the transcoders of base stations communicating with the terminal equipment to a mode in which the transcoders adapt the rate to fit the transmission network, but do not encode the speech signal.
Patent NO-973309-D0 (NO)
Inventor: HARGET DAVID CHARLES
IPC: B29C48/09
Filed: 1997-07-17
Abstract: A plastics pipe which comprises an inner core and an outer protective layer, in which 
the dimensions of the pipe and the protective layer are such that the ratio of the external diameter of the pipe to the thickness of the protective layer is at least 70, preferably at least 100, and 
the cohesive strength of the outer protective layer, excluding any lines of weakness, at least at the ends of the pipe is greater than the strength of the adhesive bond between the outer protective layer and the inner core.
Patent NO-975199-D0 (NO)
Inventor: EVERETT DAVID BARRINGTON
IPC: G06Q40/02
Filed: 1997-11-12
Abstract: PCT No. PCT/GB96/01146 Sec. 371 Date Jan. 27, 1988 Sec. 102(e) Date Jan. 27, 1988 PCT Filed May 14, 1996 PCT Pub. No. WO96/36947 PCT Pub. Date Nov. 21, 1996A value transfer system for transferring value in transactions between electronic purses as electronic cash has a transaction failure recovery procedure whereby a pending log stores transaction messages after they are sent. On detection of an error an interface device (IFD) can issue a payment resume command to re-send the last transaction message and resume the transaction.