baber/WOPTO huggingface dataset:
Patent ES-527353-A0 (ES)
IPC: C07C275/68
Filed: 1983-11-17
Abstract: New nitrosourea compounds that can be used as medicaments and correspond to the general formula I    <IMAGE>  (I)  in which R1 is hydrogen, C1-C6 alkyl or phenyl, R2 is hydrogen, C1-C6 alkyl, thienyl, or phenyl which may carry substituents, R3 is hydrogen, C1-C6 alkyl, or benzyl which may carry substituents, or R2 and R3 together represent -(CH2)m-, m being 3 or 4. Pharmaceutical compositions; therapeutic administration especially for the treatment of tumours.
Patent ES-531747-A0 (ES)
IPC: C08F36/04
Filed: 1984-04-18
Abstract: An improved polymerization catalyst, its preparation, and use are disclosed. The catalyst is one prepared by reacting a benzoic acid ester, an alkoxytitanium compound, and a magnesium halide having alkanol associated therewith to form a first catalyst component then reacting said first catalyst component with an organoaluminium halide and then reacting the resulting solid with a halogenating agent comprising a titanium halide.
Patent ES-534168-A0 (ES)
IPC: C12N5/00
Filed: 1984-07-10
Abstract: Plasmid vectors which possess restriction enzyme cutting sites at 0.1 kb and 2.35 kb by Hind III, at 0.6 kb and 3.1 kb by Kpn 1, at 3.07 kb by Bam HI and 1.45 kb by Sal I, based upon the Eco RI cutting site at 0 kb.
Patent ES-536882-A0 (ES)
IPC: C11D3/08
Filed: 1984-10-18
Abstract: The formation of poorly-dispersioie material by interaction between sodium silicate and sodium aluminosilicate in a detergent powder can be reduced by acidification of the slurry prior to spray-drying. An acid in an amount equivalent to from 1.5 to 3 parts by weight of hydrogen chloride per 6 parts of sodium silicate of sodium oxide to silica ratio 1 to 1.6 is added to precipitate at least part of the silicate. Optionally, a powder-structurant is present.
Patent ES-542777-A0 (ES)
IPC: B29K103/08
Filed: 1985-04-30
Abstract: Disclosed is a vapor generator for generating a supply of a gas bearing vapors of a compound at a desired concentration. The supply of gas bearing vapors can be generated on demand at a desired constant delivery pressure. The generator comprises a gas line for conveying pressurized gas from a source thereof through first pressure regulating means to a vessel; said vessel for retaining a reservoir of said compound in its liquid phase and having headspace thereabove, said vessel being insulated and having heating means to maintain said liquid and said headspace at a desired temperature. The gas line extends into the vessel to a position within the reservoir of liquid and there is terminated with gas distributor means. The vessel is provided with a product vaporous outlet from the headspace from which a gas outlet line connects to a second pressure regulator means. The first pressure regulator means independently controls the pressure in the vessel while the second pressure regulator means independently controls the delivery pressure of the gas bearing said vapors. The concentration of vapors in the supply of outlet gas is determined by the vessel pressure and vessel temperature. Advantageously, the generator may be portable and may be used to generate vaporous amine carried by air or an inert gas.
Patent ES-545232-A0 (ES)
IPC: C07D209/16
Filed: 1985-07-16
Abstract: A process for the preparation of N-acetyl serotonine characterised in that serotonine is acetylated to form N, O-diacetyl serotonine which is then treated with an alkaline mixture of water and a lower alcohol to selectively hydrolyse the O-acetyl group of the N, O-diacetyl serotonine to give N-acetyl serotonine. The melatonine is prepared by methylating the N-acetyl serotonine in the 5-position.
Patent ES-557470-A0 (ES)
IPC: C07C43/12
Filed: 1987-03-27
Abstract: For the Contracting States : BE, CH, DE, GB, LT, LI, LU, NL, SE 1. Fluorinated telogens possessing a CCl3  end group, characterized in that they correspond to the general formula : Rf-Q-CII3 in which Rf denotes a linear or branched perfluoroalkyl radical containing from 2 to 20 carbon atoms and Q denotes a linkage group chosen from those of formulae : -(CH2 )r -OCO-(CH2 )S -  see diagramm : EP0188952,P23,F1 -(CH2 )r' -COO-(CH2 )s' -  see diagramm : EP0188952,P23,F2  or Rf and Q denote together a group of formula :  see diagramm : EP0188952,P24,F3  in which : r and s' are integers ranging from 1 to 12, r' and s are integers ranging from 0 to 12, X denotes a hydrogen, chlorine or bromine atom, X denotes a -CH2 -, -CH2 -CCl2 -, -CH2 -CCl2 -CH2 - or -CH2 CCl2 -CF2 - bridge, R denotes a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, Y denotes an oxygen or sulphur atom, Z denotes a -CH2 -, -CH2 -C6 H4 - or -COO-(CH2 )t - bridge, t being an integer ranging from 0 to 9, R' denotes a hydrogen atom or a methyl group, W' denotes a direct bond or a -CCl2 -, -CCl2 -CH2 - or -CCl2 -CF2 - bridge, and u is a number ranging from 2 to 100. For the Contracting State : AT 1. Process for the preparation of fluorinated telogens of general formula : Rf-Q-CCl3 in which Rf denotes a linear or branched perfluoroalkyl radical containing from 2 to 20 carbon atoms and Q denotes a linkage group chosen from those of formulae : -(CH2 )r -OCO-(CH2 )S -  see diagramm : EP0188952,P25,F1  -(CH2 )r' -COO-(CH2 )s' -  see diagramm : EP0188952,P25,F2  or Rf and Q denote together a group of formula : see diagramm : EP0188952,P26,F3  in which : r and s' are integers ranging from 1 to 12, r' and s are integers ranging from 0 to 12, X denotes a hydrogen, chlorine or bromine atom, W denotes a -CH2 -, -CH2 -CCl2 -, -CH2 -CCl2 -CH2 - or -CH2 CCl2 -CF2 - bridge, R denotes a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, Y denotes an oxygen or sulphur atom, Z denotes a -CH2 -, -CH2 -C6 H4 - or -COO-(CH2 )t - bridge, t being an integer ranging from 0 to 9, R' denotes a hydrogen atom or a methyl group, W' denotes a direct bond or a -CCl2 -, -CCl2 -CH2 - or -CCl2 -CF2 - bridge, and u is a number ranging from 2 to 100, characterized in that a CCl3  end group is introduced onto a fluorinated compound by : a) esterification of a fluorinated alcohol or acid with, respectively an acid or an alcohol or epoxide cntaining the said CCl3  end group, or b) condensation of a fluorinated carboxylic or sulphonic acid halide with an amine containing the said CCl3  end group, or c) addition to a fluorinated olefin of a haloalkane chosen from carbon tetrachloride, bromotrichloromethane, chloroform, hexachloroethane, pentachloroethane, 1,1,1,3,3,3-hexachloropropane and 2,2-difluoro-1,1,1,3,3,3-hexachloropropane, or d) condensation of a fluorinated alcohol or thiol with the product of addition to chloromethylstyrene of one of the abovementioned haloalkanes.
Patent ES-557555-A0 (ES)
IPC: C07D417/04
Filed: 1987-05-16
Abstract: Certain substituted-4-hydroxy-(or 4-acyloxy-)2H-1,2-benzothiazine 1,1-dioxides having at the 3-position a 2-substituted-1,3,4-oxadiazol-5-yl, a 2-substituted-tetrazol-5-yl or a 1-substituted-tetrazol-5-yl group useful as selective 5-lipoxygenase pathway inhibitors; and methods for their preparation.
Patent ES-557768-A0 (ES)
IPC: C07D471/04
Filed: 1987-10-15
Abstract: The invention relates to novel compounds of the formula 
<CHEM>
 where X is H, halogen, loweralkyl, loweralkoxy, -CF3, or -OH; R is H, loweralkyl, arylloweralkyl, diarylloweralkyl, loweralkanoyl, arylloweralkanoyl or diarylloweralkanoyl; and R1 is H2, O or -NR2R3, R2 and R3 being independently H or loweralkyl, or taken together with the nitrogen atom to which they are attached constitute 
<CHEM>
, R4 in turn being H, loweralkyl, hydroxyloweralkyl, aryl, arylloweralkyl or diarylloweralkyl or pharmaceutically acceptable acid addition salts thereof, which are useful for enchancing memory. The invention relates further to a process and intermediates for the preparation of the above compounds.
Patent FI-853516-A0 (FI)
Inventor: PIGNEUL RAYMOND
IPC: A61F13/15
Filed: 1985-09-13
Abstract: PCT No. PCT/FR85/00014 Sec. 371 Date Sep. 25, 1985 Sec. 102(e) Date Sep. 25, 1985 PCT Filed Jan. 25, 1985 PCT Pub. No. WO85/03205 PCT Pub. Date Aug. 1, 1985.The invention concerns the field of hygiene and relates to a disposable article (1) combined removably with a removable belt (12), the attachment of one to the other being obtained by means of "Velcro" TM  attachment elements. The article comprises a first attachment element (11) fixed near each longitudinal edge on the external face of a trunk area (4); the means of attachment combined removably consist of a belt (12) provided at each extremity with a complementary second attachment element (16) of the first attachment element (11), and the other external trunk area (4) and/or at least one area (13) of the belt coming into contact with this external trunk area has a coefficient of friction sufficient to maintain the article in position by the combination of the first attachment elements (11) by means of the belt provided with the complementary second attachment elements (16).
Patent FI-853708-A0 (FI)
Inventor: THEUNISSEN HELMUT
IPC: H01B3/24
Filed: 1985-09-26
Abstract: Hardly inflammable and biologically degradable functional liquid comprising at least one bromine-containing benzyl toluol derivative having the general formula (I) wherein x is 1 or 2, x' is 0 or 1, y is 0, 1 or 2, y' is 0, 1 or 2, z is 0 or 1 and z' is 1 or 2, providing that the equations y + y' = 0, 1 or 2 and x + x' + y + y' = 1, 2 or 3 are verified.
Patent FI-870308-A0 (FI)
Inventor: ILMARINEN ANTTI
IPC: D21F3/04
Filed: 1987-01-23
Abstract: Method and device in the press section of a paper machine, in particular in a so-called closed press section provided with a smooth-faced press roll (10), for the control of the detaching of the paper web from the said press roll (10). In the method and by means of the device, the temperature of the face (10') of the said smooth-faced press roll (10) is adjusted. By means of this adjusting, the adhesion between the roll face (10') and the paper web (W) to be detached is affected, and thereby the detaching angle ( theta ) and/or the detaching tension (T) of the paper web is set within an optimal range. The temperature profile of the smooth-faced press roll (10) in the axial direction of the roll (10) can also be adjusted in view of controlling the detaching process.
Patent FI-900206-A0 (FI)
Inventor: GUSTAFSSON PER
IPC: E21B4/14
Filed: 1990-01-12
Abstract: In a water driven down-the-hole rock drill, the rearward end of an associated hammer is provided with a drive piston reciprocable in a cylinder located adjacent the rear of the drill. The front end of the hammer is guided for reciprocation in a bearing located adjacent an anvil of a drill bit. Between the cylinder and the bearing the hammer is elongated and enlarged diametrically relative to the piston. The enlarged hammer portion reciprocates freely in a chamber formed by an outer casing of the drill. Drive water is expelled from the cylinder and flushes the hole drilled by the bit. An open ended tubular valve reciprocates to control a duct connecting the interior of the valve to coaxial through-flushing channels in the hammer and the drill bit.
Patent FI-905770-A0 (FI)
Inventor: DUBROEUCQ MARIE-CHRISTINE
IPC: A61K31/40
Filed: 1990-11-22
Abstract: New isoindolone derivatives of general formula (I) are   <IMAGE> (I) disclosed in which the radicals R represent hydrogen atoms or, together, form a bond, the symbol R' represents a hydrogen atom or a readily removable radical and the symbols R'' are identical and represent phenyl radicals which can be substituted with a halogen atom or a methyl radical at the ortho or meta position, in the (3aR, 7aR) form or in the form of a mixture of the (3aRS, 7aRS) forms, as well as their salts. These derivatives are useful as intermediates for the preparation of therapeutically active products.
Patent FI-913152-A0 (FI)
Inventor: MAEDA YASUAKI
IPC: G11B27/36
Filed: 1991-06-28
Abstract: The disk recording appts. sequentially inputs data to a memory (14) at one transfer rate. This data is subsequently read out at a second, higher transfer rate and recorded to disk (2). The amounts of data read from the memory are set so that there is a writing space in memory. During playback, the recorded data are reproduced at a rate, higher than the rate for outputting the data, and stored in a memory (22). Again the amount of data read always maintains a minimum amount of data in the memory (22).
Patent FI-921304-A0 (FI)
Inventor: CHAMBERLAIN PETER
IPC: A01N25/10
Filed: 1992-03-25
Abstract: The systemic activity of systemic active ingredients in sprayed foliar systemic compositions is improved by incorporating water soluble polymer. The polymer can have a molecular weight sufficiently low that its presence does not substantially affect the spray pattern of the composition and such that the polymer can initially be supplied as an aqueous solution having 1 to 25% concentration. When the active ingredient is water soluble, for instance glyphosate or chlormequat, a concentrate can comprise an aqueous solution of the active ingredient and the polymer.
Patent FI-924230-A0 (FI)
Inventor: EFFLAND RICHARD CHARLES
IPC: A61P25/26
Filed: 1992-09-21
Abstract: This invention relates to substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzoÄbÜthiophenes and 1,2-benzisothiazoles of the formula <CHEM>  wherein     Q is S, N or NR<6>;     Y is CH, N or NR<6>; R<5> is hydrogen, loweralkyl, loweralkynyl, loweralkenyl, arylloweralkyl, loweralkoxycarbonylaminoloweralkylcarbonyl, arylloweralkoxycarbonyl-aminoloweralkylcarbonyl, aminoloweralkylcarbonyl, loweralkoxycarbonyl or acyl;     R<6> is hydrogen or loweralkyl;     R<7> is hydrogen or loweralkyl;     X is hydrogen, loweralkyl, halogen; and n is 0 or 1; or a pharmaceutically acceptable acid addition salt thereof. The compounds of this invention are useful in the treatment of memory dysfunctions characterized by a cholinergic deficit such as the type associated with Alzheimer's disease and other memory disorders. Compounds of this invention also have utility as modulators of neurotransmitter function such as noradrenergic and serotonergic and as such are useful for treatment of depression and personality disorders such as obesessive compulsive disorders. Additionally, compounds of this invention are useful as topical antiinflammatory agents for the treatment of various dermatoses.
Patent FI-934226-A0 (FI)
Inventor: KLAVENESS JO
IPC: A61K/
Filed: 1993-09-27
Abstract: The present invention provides contrast agents for use in diagnostic ultrasound studies comprising microbubbles of gas or a gas precursor encapsulated by non-proteinaceous crosslinked or polymerised amphiphilic moieties.
Patent FI-935318-A0 (FI)
Inventor: RENAUT PATRICE
IPC: A61P33/02
Filed: 1993-11-29
Abstract: The present invention relates to compounds of structure related to that of 15-deoxyspergualine, as new industrial products. These new compounds correspond to the formula: <IMAGE>  in which:     - n is equal to 6 or 8, - A represents a single bond, CH2, CHF, CH(OH), CH(OCH3), CH2NH or CH2O,  and their addition salts. These new compounds are useful as immunosuppressants.
Patent FI-941246-A0 (FI)
Inventor: ROENISCH WERNER
IPC: H02J7/02
Filed: 1994-03-16
Abstract: A method and a device (10) are proposed for the regeneration of voltage sources (11) in the form of primary cells (primary elements), by means of electrical energy which is supplied in the form of a DC voltage. In this case, the voltage source (11) which is to be regenerated has applied to it over a predetermined time interval voltage pulses (18) which are applied essentially cyclically, have an amplitude which can be predetermined and have a pulse length which can be predetermined. The DC voltage signal (13) required for this purpose is supplied from a low-resistance DC voltage source (23). The voltage pulse sequence (18), which is applied to one pole (19) of the voltage source (11) which is to be regenerated, is produced in a pulsed switching device (14) by means of a pulse generator (clock generator) (15). <IMAGE>
Patent FI-943454-A0 (FI)
Inventor: DAUTH JOCHEN DIPL CHEM DR
IPC: C08G77/26
Filed: 1994-07-21
Abstract: The organosilicon compounds contain at least one Si-C bonded organic radical containing at least one triazene group. The organosilicon compounds can be employed as thermo- and photolabile free-radical initiators for the preparation of homopolymers, graft copolymers and block copolymers from olefinically unsaturated compounds and for the crosslinking of organosilicon compounds and free-radical-polymerisable organic compounds.
Patent FI-944903-A0 (FI)
Inventor: CHAPMAN BARBARA
IPC: C12P/
Filed: 1994-10-19
Abstract: Recombinant protein complexes having human Factor VIII:C activity are produced in a eukaryotic host cell by expressing a DNA construct encoding said protein complex joined in reading frame with control sequences providing for the expression of said DNA construct in said host cell, wherein said DNA construct comprises a nucleotide sequence that encodes a first polypeptide homologous to the A domain of human Factor VIII:C linked to a second polypeptide homologous to the C domain of human Factor VIII:C by a polypeptide spacer, wherein the polypeptide spacer is other than the full length B domain of human Factor VIII:C and comprises an amino acid sequence homologous to a human Ig heavy chain hinge region.
Patent FI-962808-A0 (FI)
Inventor: JONKKA ARVO
IPC: B27L11/00
Filed: 1996-07-10
Abstract: PCT No. PCT/FI97/00425 Sec. 371 Date Jan. 6, 1999 Sec. 102(e) Date Jan. 6, 1999 PCT Filed Jul. 1, 1997 PCT Pub. No. WO98/01272 PCT Pub. Date Jan. 15, 1998The invention concerns a knife disc arrangement of a disc chipper, said arrangement comprising a rotating knife disc (1), knives (3), wear plates (4) and supporting strips (11) supporting the wear plates. The invention also concerns a hinge strip acting as a supporting strip (11) for the wear plate. The knives are supported against the direction of rotation of the disc by fitting the base edge (9) of the knife against a supporting surface (10). The supporting surface (10) supporting the base edge of the knife (3) is located in the supporting strip (11).
Patent FI-971995-A0 (FI)
Inventor: NISHIDA HIROYUKI
IPC: C07D311/00
Filed: 1997-05-09
Abstract: This invention provides a process for producing a macrocyclic lactone compound, which comprises cultivating Actinoplanes sp. FERM BP-3832, in the presence of L-proline, L-hydroxyproline or L-nipecotic acid, and then isolating a macrocylic lactone compound from the fermentation broth. The compounds produced by this process include a compound of the following formula:The present invention also relates to a pharmaceutical composition comprising the same, which is useful as immunosuppressive, antimycotic, antitumor agent or the like.
Patent FI-972835-A0 (FI)
Inventor: JOERGENSEN-BECK FRODE
IPC: B65D5/72
Filed: 1997-07-02
Abstract: PCT No. PCT/DK96/00002 Sec. 371 Date Jul. 7, 1997 Sec. 102(e) Date Jul. 7, 1997 PCT Filed Jan. 4, 1996 PCT Pub. No. WO96/20873 PCT Pub. Date Jul. 11, 1996In carton boxes of that particular dispenser type, where the broad front side (2) of the box exhibits a dispenser opening, which is internally covered by a slide panel (18) with an opening (20), the slide panel is displaceable into a dispensing position by an outward pivoting of an associated end flap (26) of the box. The slide panel is prevented from falling into the box in that it has laterally projecting side flaps (28) which ride on the top edges of inner, upright side wall portions (8) of the box, this riding engagement being secured by the side flaps being folded down along the upper, exterior area of the side wall portions (8). Outer side wall portions (12) folded own from the front or top panel (2) are at their lower edge area welded or glued to the root zone of the inner, upright side wall portions. The associated folding of the said side flaps (28) may result in an inward pivoting of the inner side wall portions (8), which in turn disables a perfect face-to-face engagement in the lower joining zone (A, B) between the side wall portions. According to the invention this drawback is eliminated in arranging for a longitudinal cutting line (C) near the middle of the inner side wall portion (8), such that by the folding down of the side flap (28) it will only be the strip area above this line which is forced inwardly, while the remaining lowermost strip area can be joined safely face to face with the outer side wall portion (12).
Patent FI-982427-A0 (FI)
Inventor: JAERVENKYLAE JYRI
IPC: F16L9/18
Filed: 1998-11-09
Abstract: The invention relates to a method of making a pipe, and a pipe. The pipe consists of an outer pipe (2) providing mechanical strength and of an inner layer providing tightness. The outer pipe (2) and the inner layer are formed from semi-finished products that require substantially less space during storage than finished pipes. The outer pipe (2) is made for example by winding a profile (1) into a helix. The outer pipe (2) is coated from the inside before it is taken into use by inserting a flexible inner lining (4) into the pipe. The inner lining (4) is rounded against the outer pipe (2), and the inner lining (4) and the outer pipe are joined so that the inner lining (4) forms an inner layer acting as a flow surface.
Patent AP-9300560-A0 (AP)
Title: Novel indole and derivatives, processes for their use as medicaments.
Inventor: FORBES IAN THOMSON
IPC: C07D209/00
Filed: 1993-08-19
Abstract: Compounds of formula (i): wherein: p represents a quinoline or isoquinoline residue, or a 5- or 6-membered aromatic heterocyclic ring containing up to three heteroatoms selected from nitrogen, oxygen or sulphur; r1 is hydrogen or c1-6 alkyl; r2,r3,r10 and r11 are independently hydrogen or c1-6 alkyl, or r10 and r11 together form a bond, or r2 and r10 or r3 and r11 together form a c2-6alkylene chain; r4 hydrogen, c1-6 alkyl, halogen, nr8r9 or12, where r8,r9 and r12 are independently hydrogen or c1-6 alkyl; r5 is hydrogen or c1-6 alkyl; r7 is hydrogen, c1-6 alkyl, or12 or halogen, where r12 is hydrogen or c1-6 alkyl; n is 2 or 3; and the groups r13 and r14 are independently hydrogen or c1-6 alkyl, processes for their preparation and their use as medicaments are disclosed.
Patent IL-73090-A0 (IL)
Title: 5h-(1)benzopyrano(2,3-d)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D491/052
Filed: 1984-09-26
Abstract: The invention relates to 5H-[1]benzopyrano-[2,3-d]pyrimidine derivatives of the general formula I    <IMAGE>  (I)  which may be prepared by means of a new chemical process and have a protective effect similar to that of cimetidine, but do not exhibit the undesired side effects of antisecretory agents. The invention is based on a new mucoprotective mode of action which prevents lesions of the mucous membrane epithelium to arise.
Patent IL-78790-A0 (IL)
Title: Oxadiazolyl imidazobenzodiazepine compound,pharmaceutical compositions containing said compound,method of preparing said compound and method of treating a central nervous system ailment
IPC: C07D487/04
Filed: 1986-05-15
Abstract: The application discloses novel benzodiazepine agonist compounds, namely, 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-7-ha lo-4H-imidazo [1,5-a][1,4]benzodiazepines, pharmaceutical compositions thereof, and a method of ameliorating central nervous system ailments therewith, especially convulsions and anxiolytic states. A novel intermediate and process for their production are also disclosed.
Patent IL-86904-A0 (IL)
Title: Transdermal therapeutic system
IPC: A61M37/00
Filed: 1988-06-28
Abstract: PCT No. PCT/DE88/00370 Sec. 371 Date Apr. 3, 1989 Sec. 102(e) Date Apr. 3, 1989 PCT Filed Jun. 21, 1988 PCT Pub. No. WO89/00437 PCT Pub. Date Jan. 26, 1989.The invention relates to a transdermal therapeutic system for administering or applying active substances to the skin with a backing layer remote from the skin, an active substance depot, an active substance delivery control means controlling the delivery of the active substance through the system and a contact adhesive means for fixing the therapeutic system to the skin, in which the active substance depot is a multichamber system, in which discreet chambers contain one or more active substances.