baber/WOPTO huggingface dataset:
Patent ES-8307733-A1 (ES)
Title: Process for the preparation of a thioester of [alpha]- mercaptopropionylglycine
IPC: A61K31/225
Filed: 1982-05-24
Abstract: The thioester of α-mercaptopropionylglycine with p-isobutylphenylpropionic acid has simultaneous anti- inflammatory and mucolytic properties. It is prepared by the reaction of a reactive derivative of p-isobutylphenyl- propionic acid and α-mercaptopropionylglycine at low temperature in a polar solvent. The salts with organic and inorganic bases, with basic amino acids and with basic antibiotics are stable and in general soluble in water, with the result that the active ingredient according to the invention can be formulated for oral, parenteral, rectal and topical administration.
Patent ES-8308706-A1 (ES)
Title: Filter medium in the form of a stable porous body.
IPC: B01D39/20
Filed: 1982-10-05
Abstract: Filter medium in the form of a stable porous body consisting of grains of spherical shape, bonded together by another phase or by sintering. Preferably, hollow-spherical grains of corundum are processed to give filter media in plate form. The filter media are used for the filtration of molten metals, preferably aluminium.
Patent ES-8308433-A1 (ES)
Title: A power controller.
IPC: H02P/
Filed: 1982-10-27
Abstract: This invention provides a power controller for an electrical load (4) of variable power factor, comprising switching means (1, 2, 3) which control alternating currents supplied to the load (4), and control means (12-19) which control the non-conduction angle of the switching means (1, 2, 3) such that the non-conduction angle is proportional to an applied control reference voltage (f) and such that the non-conduction angle is substantially independent of the load power factor. The power controller can improve the efficiency of a motor (4) when the motor is operating under reduced load conditions. The described power controller can also be used to adjust the applied voltage to the motor (4) in such a manner that the start current equals a preset current until the motor has reached full speed. In one embodiment, efficiency of the motor is improved by monitoring the angle between the voltage and current zero crossing, comparing this monitored angle with a reference angle and controlling the voltage in such a manner as to maintain this angle equal to a preset angle for applied voltages less than full voltage.
Patent ES-8400858-A1 (ES)
Title: Method and apparatus for assembling sliders on an uncut fastener chain.
IPC: A44B19/62
Filed: 1982-12-28
Abstract: A method and apparatus for feeding sliders to a slider pocket are disclosed. Sliders taken from the pocket are assembled on the fastening element sections of an uncut fastener chain which is moved and stopped intermittently to allow the assembly of the sliders wherein sliders longitudinally aligned and delivered by a slider chute are fed into a slider holder one at at time. The slider holder carrying a slider received from the chute is transferred to a slider assembling station from a direction at right angles to the direction of fastener chain transfer, and the slider is loaded at the slider assembling station into the slider pocket which is provided at the upper end of a slider pocket block raised from the direction at right angles to both the fastener chain transfer direction and slider transfer direction, and the slider holder is returned to the exit of the slider chute. These steps are repeated in synchronism with the stopping of movement of the uncut fastener chain. In loading the sliders into the slider pocket, the sliders are introduced from the side of the pocket so that the slider pull tab will not pose an obstacle, regardless of its shape.
Patent ES-8403126-A1 (ES)
Title: Enantiomers of 2,3,3a,4,5,6- hexahydro-1H-indolo(3,2,1- de)-[1,5-naphthyridine]
IPC: C07D471/16
Filed: 1983-05-17
Abstract: Enantiomers of the title compound of the formula: < IMAGE > which have hitherto not been characterised specifically, are isolated from their mixtures by preparing addition salts with an enantiomer of a chiral acid. The diastereoisomers obtained are separated by fractional crystallisation and then converted back to the form of the base or of a pharmaceutically acceptable acid addition salt. The enantiomers of the above named compound are useful in therapy as they possess an antianoxic activity.
Patent ES-8405236-A1 (ES)
Title: Soil cultivating implement.
IPC: A01B39/04
Filed: 1983-08-10
Abstract: A cultivating implement is intended to loosen the soil without significant distrubance of the soil surface. The implement has a frame and at least one soil working tool mounted on the frame. The tool includes a blade with a lower inclined portion and an upper upright portion which portions are interconnected by an intermediate portion. The inclined portion is moved edgewise through the ground and lies at an acute angle to the vertical to lift soil lying above the inclined portion. The intermediate portion is located in use at or below ground level. The intermediate portion may comprise a bend or the blade may be curved over the intermediate and inclined portions. The blade may be preceded by a disc arranged to cut a slot in the ground to be entered by the blade. The disc is rotatable about a horizontal axis.
Patent ES-8604543-A1 (ES)
Title: Piperazine derivatives with anticholinergic and/or antihistaminic activity
IPC: C07D295/12
Filed: 1983-09-26
Abstract: Compounds of formula I < IMAGE > (I) are described in which R is an aryl, substituted aryl, aralkyl or heterocyclic radical R1 is hydrogen or alkyl of 1-4 carbon atoms A is a saturated, aliphatic hydrocarbon chain, which is linear or branched R2 and R3 are the same or different and are hydrogen, linear or branched alkyl, aryl, substituted aryl or together with the nitrogen atom to which they are connected and together with y form a ring wherein y is a methylene group or a heteroatom, which is selected from the group consisting of nitrogen, oxygen and sulfur R4 is hydrogen or linear or branched alkyl X is halogen or an organic or inorganic anion n is 0 1 2 3 or in the case of a bifunctional acid, n is equal to 0.5 1.5 2.5 and their enantiomers and diestereoisomers. Several methods of preparation of the novel compounds are described.
Patent ES-8501086-A1 (ES)
Title: Manually engaged and automatically disengaged locking device for a vehicle differential
IPC: F16H48/30
Filed: 1983-12-20
Abstract: The device is provided with an engagement pin carried by a differential housing of the differential operable to rigidly angularly interconnect the differential housing with one of the bevel gears of the differential, and an actuator manually controlled by an operator to bring the engagement pin from a rest position to a working position. The device is further provided with a spring for urging the engagement pin towards the rest position, and locking device for releasably locking the engagement pin against the action of the spring the locking device automatically disengages, and disengaging the engagement pins when the vehicle brake is actuated, there being provided a hydraulic disengagement piston connected to a brake.
Patent ES-8501352-A1 (ES)
Title: Baffle moving and alignment means for the four gob glass forming machine
IPC: C03B9/34
Filed: 1983-12-21
Abstract: A glassware forming machine is shown which has a baffle support arm. The baffle support arm provides for four individual baffle holders which are grouped in adjacent pairs. The pairs of holders are interconnected by an equalizer arm and are biased into position by a leaf spring above and by a coil spring below. The equalizer arms are connected intermediate their lengths to a third larger equalizer bar which is pivoted for a rocking motion. The apparatus further comprises means for lifting and moving the baffle support arm and a latch means for changing the baffle holders.
Patent ES-8501876-A1 (ES)
Title: Method of measuring and controlling the level of liquid in a container.
IPC: G01F23/28
Filed: 1984-03-28
Abstract: A method is provided for measuring and controlling the level of an elevated temperature liquid in a container. The electrical voltage signal outputs of a plurality of temperature sensing devices at spaced elevations on the container are converted to digital form. The converted signals are periodically scanned in elevation sequence. A determination is made from the scanned signals of the location of the uppermost sensing means having a converted signal value of sufficient magnitude to indicate a temperature in the wall below the level of liquid in the container. Then a fraction, F, of the spacing between the sensing means, n, and the next above sensing means, n-1, is calculated as a function of the converted signal value, Sn-1. The measured level in the container is calculated as a function of, n, and, F, with respect to their location on the container. Finally, the rate of addition and withdrawal of liquid to and from the container is controlled based on the measured liquid level in the container.
Patent ES-8607297-A1 (ES)
Title: Thiazolidine derivatives, their preparation and compositions containing them.
IPC: C07D493/04
Filed: 1984-08-30
Abstract: The compounds of formula (I): < IMAGE > (I) [in which: R1 and R2 are the same or different and each represents hydrogen or C1-C5 alkyl R3 represents hydrogen, an acyl group, a (C1-C6 alkoxy)carbonyl group or an aralkyloxycarbonyl group R4 and R5 are the same or different and each represents hydrogen, C1-C5 alkyl or C1-C5 alkoxy, or R4 and R5 together represent a C114 C4 alkylenedioxy group n is 1, 2 or 3 W represents the -CH2-, >CO or >CH-OR6 group (in which R6 represents any one of the atoms or groups defined for R3 and may be the same as or different from R3) and Y and Z are the same or different and each represents oxygen or imino] and pharmaceutically acceptable salts thereof have various valuable therapeutic effects on the blood system and may be prepared by a process which includes reacting a corresponding halopropionic acid derivative with thiourea.
Patent ES-8600025-A1 (ES)
Title: Button orienting and placing apparatus.
IPC: A41H37/10
Filed: 1984-10-17
Abstract: In a button orienting and placing apparatus, a pushing mechanism, for pushing a button out of a guide channel in a horizontal guide, includes a slide slidable in and along the guide channel, and a horizontal pushing plate pivotally mounted on the slide and having on its forward end a pushing surface engageable with a shank of the button so as to push the latter forwardly and against one of a pair of opposed side walls of the guide as the slide is moved forwardly along the guide channel. The pushing mechanism also includes a locking lever vertically pivotally mounted on the slide and having at its forward end a single downwardly directed claw projecting through an opening in the pushing plate for catching a tab of the button to thereby stop turning of the button.
Patent ES-8705408-A1 (ES)
Title: 1,5-Benzothiazephine derivatives, processes for preparing the same and pharmaceutical compositions.
IPC: C07D281/10
Filed: 1985-04-10
Abstract: Novel 1,5-benzothiazepine derivatives of the formula: < IMAGE > (I) wherein R1 is hydrogen or lower alkyl, R2 is hydrogen, lower alkanoyl or benzyl, R3 is hydrogen or lower alkyl and either one of R4 and R5 is hydrogen and the other is chlorine, or a pharmaceutically acceptable acid addition salt thereof are disclosed. Said derivative (I) and its salt have a potent platelet aggregation-inhibiting activity.
Patent ES-8607613-A1 (ES)
Title: Mulitple-setting control for vehicle indicating and/or operating device.
IPC: B60Q1/14
Filed: 1985-04-30
Abstract: Control (1) having a supporting body (4) designed to be fitted integral with the steering column and having opposite cup-shaped side members (12) housing, in removable manner, at least one pre-assemblable control box (5) from which depart a control lever (2) and connectors (15) for connection to the electric circuit on the vehicle the said box (5) containing means (40, 41) for securing and enabling angular displacement of the said lever in a number of different positions, and switch means consisting of a printed circuit (28) fitted with a sliding pad (35) and the said connectors (15) and on which may be pre-assembled all the electrical components on the control (1) independently of the mechanical components on the same.
Patent ES-8700567-A1 (ES)
Title: Injection of nicardipine hydrochloride and production thereof.
IPC: A61K47/00
Filed: 1985-05-21
Abstract: This invention provides an injection of nicardipine hydrochloride comprising an aqueous nicardipine hydrochloride solution containing 2 to 7 w/v % of polyhydric alcohol and having a pH of 2.5 to 5.5.
Patent ES-8607043-A1 (ES)
Title: Method of homogenisation by piling and withdrawing bulk materials on a circular surface.
IPC: B65G69/10
Filed: 1985-05-24
Abstract: 1. Method of homogeneisation by piling and reclaiming bulk materials on a circular surface (1) where a dead pile (M) was formed beforehand, according to which, alternatively on each face of the dead pile (M), a pile of materials is formed which rests on the said face, while the pile formed previously is being reclaimed, each pile in an odd rank being leaned against one of the faces of the dead pile (M) and each pile in an even rank being leaned against the other face of the said dead pile, characterized by the fact that the space left available on the circular surface by the angular extent (alpha) of the dead pile (M) and that (beta) of a reclaimer (10) is divided into at least three sectors one of which is cyclically allocated for stacking, another one is cyclically allocated for reclaiming and the other one(s) support(s) a formed pile, and by the fact that each pile is formed by leaning against one another a plurality of elementary piles the angular extent of which is equal to that of the sectors on which they are formed, so that the angular extent of each pile reaches a pre-determined value above 1808.
Patent ES-8704317-A1 (ES)
Title: Automatic, gradual opening assembly of valves for controlling the passage of fluid
IPC: A01G27/00
Filed: 1986-06-18
Abstract: The invention consists essentially in a general supply conduit from which depart upwards branches which have at their upper end a valve which cuts off the principal flow of the fluid by means of the pressure existing in the pipe through an intermediate element. Collaborating in this operation are an upper cylinder with a piston placed close to another tubular retention element and one more piston, connected to the first one by a rod, displaced downwards, which regulate the passage of the fluid through the respective conduits, it sufficing, to initiate irrigation, of a smallholding (farm) in this case, to open the main valve for the passage of water under pressure.
Patent ES-8801230-A1 (ES)
Title: 1,5-Benzothiazephine derivatives, processes for preparing the same and pharmaceutical compositions.
IPC: C07D281/10
Filed: 1986-09-11
Abstract: Novel 1,5-benzothiazepine derivatives of the formula: < IMAGE > (I) wherein R1 is hydrogen or lower alkyl, R2 is hydrogen, lower alkanoyl or benzyl, R3 is hydrogen or lower alkyl and either one of R4 and R5 is hydrogen and the other is chlorine, or a pharmaceutically acceptable acid addition salt thereof are disclosed. Said derivative (I) and its salt have a potent platelet aggregation-inhibiting activity.
Patent IE-911734-A1 (IE)
Title: Preservation of cells as controls or standards in cellular analysis
Inventor: DAVIS KENNETH A
IPC: G01N33/569
Filed: 1991-05-21
Abstract: Cells fixed with a fixative, reduced with a Schiff's base reducing agent and then dried in the presence of  alpha - alpha -trehalose retain their light scatter and fluorescence properties and may be used, when rehydrated, as standards or controls in cellular analysis.
Patent IE-902386-A1 (IE)
Title: Improved tipping system
Inventor: OSTERMEYER BERND
IPC: B60P1/04
Filed: 1990-06-29
Abstract: PCT No. PCT/AU90/00274 Sec. 371 Date May 28, 1991 Sec. 102(e) Date May 28, 1991 PCT Filed Jun. 27, 1990 PCT Pub. No. WO91/00195 PCT Pub. Date Jan. 10, 1991.A tipping system for use in a vehicle including a container having an upper perimetrical frame with an open top and a bowl made of flexible material is suspended from the frame and including means to interact with the bowl in the discharge position to control the shape of the bowl so that contents carried therein will gravity discharge over one side of the perimetrical frame, is disclosed.
Patent IE-902583-A1 (IE)
Title: "Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis"
Inventor: DORIA GIANFEDERICO
IPC: C07D495/04
Filed: 1990-07-16
Abstract: PCT No. PCT/EP90/01129 Sec. 371 Date Mar. 12, 1991 Sec. 102(e) Date Mar. 12, 1991 PCT Filed Jul. 11, 1990 PCT Pub. No. WO91/01309 PCT Pub. Date Feb. 7, 1991.Heteroaryl-3-oxo-propanenitrile derivatives of formula (I)   <IMAGE> (I)  wherein X represents an oxygen atom or a -CH(R4)-, -O-CH(R4)-,-S(O)n-, -S(O)n-CH(R4)-, -CH(R4)-O-, -CH(R4)-S(O)n- or -CH(R4)-CH2- group wherein n is 0, 1 or 2; R1 represents C1-C6 alkyl, pyridyl or unsubstituted or substituted phenyl; R2, R3 and R4 are as herein defined; and Q is hydrogen, carboxy, C2-C7- alkoxycarbonyl or a -CON(Ra)Rb group, Ra and Rb being as defined herein; and their pharmaceutically acceptable salts are useful in stimulating myelopoiesis in bone marrow suppressed mammals.
Patent IE-902753-A1 (IE)
Title: Supercritical fluid and near critical gas extraction of organic solvents from formed articles
Inventor: HEIT LAWRENCE B
IPC: B01J8/02
Filed: 1990-07-30
Abstract: Disclosed is a method of removing residual organic solvents from formed compressed articles such as tablets comprised of subjecting the organic solvent laden compressed article to a supercritical fluid or near critical gas whereby residual solvent is transferred from the solvent laden solid article to the supercritical fluid or near critical gas and separating the residual solvent depleted compressed article from the solvent enriched supercritical fluid or near critical gas.
Patent IE-913655-A1 (IE)
Title: Synergistic agents
IPC: A61K31/535
Filed: 1991-10-17
Abstract: The invention relates to synergistic agents for the treatment of inflammatory or arthritic conditions which comprise one of a selected group of inhibitors of the enzyme 5-lipoxygenase in conjunction or admixture with an inhibitor of the enzyme cyclooxygenase. Conveniently the 5-lipoxygenase inhibitor is, for example, 6-[(3-fluoro-5-[4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl]phenoxy)met hyl]-1-methyl-2-quinolone or 4-[5-fluoro-3-(4-methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-7-ylthio)p henyl]-4-methoxytetrahydropyran and the cyclooxygenase inhibitor is selected from indomethacin, flurbiprofen and diclofenac. The invention also relates to a pharmaceutical composition containing said synergistic agent and to the use of said agent in the manufacture of a medicament for the synergistic treatment of inflammatory or arthritic disease.
Patent IE-913939-A1 (IE)
Title: An insulating window
IPC: B60J10/273
Filed: 1991-11-13
Abstract: An insulated window for motor vehicles, which consists of two window panes arranged at a distance from one another, the distance being maintained by means of a sealing frame which runs around the edge region of the panes and dry air at normal pressure being introduced between the panes, the degree of dryness of said air being maintained by drying means arranged in the region of the sealing frame, is to be constructed in such a way that it can be manufactured in a simple manner without adversely affecting its functional capacity. For this purpose, there is provision according to the invention for a prefabricated dimensionally stable frame (shaped frame) made of rubber or rubber-like plastic to be inserted between the two window panes and for an injection moulding which surrounds the entire edge of the insulated window to be provided after the two window panes have been laid one on top of the other, which moulding holds together the two window panes and at the same time places the shaped frame under pretensioning so that a sealed capsule is produced.
Patent IE-904126-A1 (IE)
Title: Needle Assembly
Inventor: SWEENEY NIAL
IPC: A61M5/34
Filed: 1990-11-15
Abstract: A needle assembly (20) includes an elongate cannula (21) having a first end (34), an opposite end (35) and a sidewall (37) therebetween. The cannula includes a lumen therethrough defining a cannula longitudinal axis (39). A hub (22) having a proximal end (40), a distal end (41) and a passageway (43) therethrough defining a longitudinal axis (44) is provided. The passageway (43) includes an enlarged first portion (45) at the distal end, a second portion (46) adjacent to the first portion (45) and a third portion (47) adjacent to the proximal end. The cannula (21) is positioned in the hub (22) so that the opposite end (35) is within the second portion (46) and the first end (34) projects outwardly from the distal end (41) of the hub (22). The second portion (46) includes a proximally located ledge (49) for establishing the most proximal position of the cannula (21) in the passageway (43) and an inwardly projecting flange (51), located distally from the ledge (44), for contacting and holding a cannula (21) with sufficient force to prevent the cannula (21) from falling out of the hub (22). The annular flange (51) and the ledge (49) interact with the cannula (21) so that the angular relationship between the cannula (21) longitudinal axis and the hub (22) longitudinal axis can be varied and the cannula (21) movably held in a selected angular relationship. Adhesive (23) is provided in the volume described by the first portion for holding the cannula (21) fixedly in the selected angular relationship with respect to the hub (22). <IMAGE>
Patent IE-914159-A1 (IE)
Title: Processes and intermediates for thromboxane receptor¹antagonists
IPC: A61P7/02
Filed: 1991-11-29
Abstract: Disclosed herein is a process for preparing a monoacyl of the formula in which the associated diacyl is hydrolyzed in the presence of one or more water-soluble enzymes or microorganisms capable of selectively hydrolyzing the -O-C-(O)-R<1> group, wherein the treatment is carried out in a biphasic solvent system comprising an aqueous phase having the enzymes or microorganisms and an organic phase immiscible in water having the diester. This acyl-alcohol is oxidized to the associated acyl-aldehydes, which are hydrolyzed with an alkali metal carbonate, bicarbonate or hydroxide to the cis furanol. The thromboxane receptor antagonist [1S-[1 alpha ,2 alpha (Z),3 alpha ,4 alpha ]]-7-[3[[[[(1-oxoheptyl)-amino]acetyl]amino]methyl-7-oxabicyclo-[2.2.1 ]-hept-2-yl]-5-heptenoic acid may be prepared using these processes.
Patent IE-920055-A1 (IE)
Title: Improvements in and relating to hormones
IPC: C07K16/00
Filed: 1992-01-08
Abstract: An analog of piscine GnRH is disclosed having the amino acid sequence: pGlu-His-Trp-Ser-Tyr-W-Trp-Leu-Arg-Pro-Gly-X-Y-Z wherein W represents Gly or a D-amino acid, X represents a bond, or one or more amino acids which may be the same or different, Y represents Cys or Tyr or is absent, and Z is absent or represents one or more amino acids which may be the same or different or a continuous or discontinuous peptide chain, the or each discontinuity being a non- alpha amino acid polyfunctional linker moiety or a retro-inverso amino acid with the proviso that when W is Gly and X and Y are absent Z is present. The analog may be conjugated to a carrier and used, for example, to delay onset of sexual maturation and enhance growth.