baber/WOPTO huggingface dataset:
Patent CZ-291784-B6 (CZ)
Title: Method for hardening the surface of meat products or raw sausages using ultrasonic treatment
Inventor: KORTSCHACK FRITZ
IPC: A23L13/60
Filed: 1999-10-14
Abstract: The present invention relates to a method for hardening the surface of meat products or raw sausages using ultrasonic treatment during a continuous process, wherein the method comprises the following steps: largely degassing the raw product, subsequently bringing it into direct contact with the surface of one or more ultrasonic sonotrodes, whereby at least one of the ultrasonic sonotrodes is heated in order to achieve uniform denatured layer, making a thin, dense and  dimensionally stable coagulation natural skin on the surface of the raw product by at least temporary action thereon of ultrasonic power within a low frequency range but a high oscillation amplitude and finally transferring the row product to another treatment or packaging.
Patent CZ-292370-B6 (CZ)
Title: Lifting device
Inventor: STRUCK DETLEF
IPC: B66D3/26
Filed: 2000-12-02
Abstract: The present invention relates to a lifting device for raising, lowering and pulling loads. A hand chain wheel (2) is covered by a rotatably supported cover (14) having chain (3) guide openings (15, 16). The cover (14) is rotatably secured by a supporting metal sheet (17), which is located on a side plate (12) of a housing (11) that accommodates the load chain (6) wheel (5). A radially outwardly oriented guide (18) disposed on the cover (14) engages with a slide ring (20) of the supporting metal sheet (17). The slide ring (20) has a central recess (19) for the cover (14).
Patent CZ-298127-B6 (CZ)
Title: Chucking device
Inventor: ROEHM GUENTER HORST
IPC: B23Q3/00
Filed: 2001-11-29
Abstract: A hollow shank (1) has in its fixture (2) obliquely extending clamping bevels (7). Chuck jaws (8) that can be brought into bearing contact and having corresponding bevels (9) are mounted on these clamping bevels (6). An axially slidable and in a working spindle (4) guided chucking head (13) produces thrust between the hollow shank (1) and the working spindle (4) controlling thus said chuck jaws (8). In order to perform a wedge mechanism, a cone surface (14) is made on the chucking head (13). Said cone surface (14) interacts with the chucking head (12) of each chuck jaw (8) provided with the bevel (9). The cone surface (14) is modified by first plane surfaces (24) being regularly distributed on the circumference wherein said plane surfaces (24) are adapted to interact with plane bearing surfaces (25) being performed on the chucking heads (12).
Patent CZ-296200-B6 (CZ)
Title: Active correction night trunk orthesis
Inventor: CERNY PAVEL
IPC: A61F5/03
Filed: 2002-10-23
Abstract: In the present invention, there is disclosed an active correction night trunk orthesis with one-sided fastening, consisting of a pelvis part (1), a lumbar part (2) and a chest part (3), wherein said pelvis part (1) is connected with said lumbar part (2) by means of a first joint (4), while said lumbar part (2) is connected with said chest part (3) by means of a second joint (5), wherein on the opposite side of said connection of the lumbar part (2) and the chest part (3) said lumbar part (2) and said chest part (3) are connected by means of a first telescope (7), while on the opposite side of the connection of the pelvis part (1) and the lumbar part (2) said pelvis part (1) and said lumbar part (2) are connected by means of a second telescope (6).
Patent SK-285139-B6 (SK)
Title: Composition in a form of microemulsion pre-concentrate comprising cyclosporine and use thereof
Inventor: AMBUHL MICHAEL
IPC: A61K9/00
Filed: 1999-03-04
Abstract: A microemulsion pre-concentrate comprises a difficultly soluble active agent and a carrier medium. Active agent can be for example cyclosporine or macrolide.
Patent BR-PI0112205-B8 (BR)
Inventor: SHIN-ICHIROH OKA
IPC: A61M1/34
Filed: 2001-07-10
Abstract: A blood processing filter comprising: 
(1) a flexible container, which has a blood inlet port and a blood outlet port, 
(2) a sheet-like filter element for removing undesirable components from blood, wherein the blood inlet port is separated from the outlet port by the filter element, and 
(3) a seal zone formed by integrating the section near the periphery of the sheet-like filter element with the flexible container over its entire circumference,  
wherein the cross-section of the seal zone comprises at least five layers from the blood inlet side to the outlet side: 
(i) a layer consisting only of the inlet side flexible container material, 
(ii) an inlet port side composite material layer wherein the inlet side flexible container material is mixed with the filter element material, 
(iii) a layer consisting only of the filter element material, 
(iv) an outlet portside composite material layer wherein the outlet port side flexible container material is mixed with the filter element material, and 
(v) a layer consisting only of the outlet port side flexible container material wherein both the inlet port side composite material layer and the outlet port side composite material layer have a thickness between 0.15 mm and 0.4 mm.
Patent EP-1126124-B8 (EP)
Inventor: LAMSFUSS NORBERT
IPC: E06B3/48
Filed: 2001-02-08
Granted: 2006-08-16
Abstract: The sealing facilities (9) are heated, with heating facilities (11), which are arranged in the endface, edge near the region of the sections (1). They are designed as rubber hollow chamber sections (9) and in at least one hollow chamber a heating cable (11) is arranged. The sealing facilities are designed as rubber sealing strips (12) arranged on the distance holders (6,7), under which a heating cable is laid. The heating cable is arranged between an insulating mat covering the insulating material and the distance holder (6).
Patent EP-1356063-B8 (EP)
Inventor: VIERSTRA RICHARD D
IPC: C12N15/82
Filed: 2001-01-30
Granted: 2005-08-10
Abstract: A method is disclosed for the production of multiple proteins in transgenic plants. A DNA construct for introduction into plants includes a provision to express a fusion protein of two proteins of interest joined by a linking domain including plant ubiquitin. When the fusion protein is produced in the cells of a transgenic plant transformed with the DNA construction, native enzymes present in plant cells cleave the fusion protein to release both proteins of interest into the cells of the transgenic plant. Since the proteins are produced from the same fusion protein, the initial quantities of the proteins in the cells of the plant are approximately equal.
Patent EP-1294545-B8 (EP)
Inventor: KLUDJIAN DAVID J
IPC: B26B27/00
Filed: 2001-06-01
Granted: 2007-04-18
Abstract: A razor handle, shaving system and shaving device whereby precise finger-tip control of the pitch, angle and pressure applied the fixed or replaceable shaving blades may be precisely controlled via the incremental movement of a ring shaped cylindrical handle.
Patent EP-1571114-B8 (EP)
Inventor: OGURA MANABU
IPC: B66B21/02
Filed: 2002-12-11
Granted: 2012-08-22
Abstract: La présente invention a trait à un escalier roulant grande vitesse pour partie inclinée, dans lequel lors du passage d'une marche (5) sur une partie de renversement (F), un premier chaînon (21) et un deuxième chaînon (22) sont déplacés tout en étant déployé et escamoté, grâce à quoi même si un rail de guidage pour galets d'entraînement est conformé en un arc de cercle simple, le trajet de déplacement des galets d'entraînement (11) peut être maintenu, permettant ainsi le fonctionnement de renversement de l'escalier roulant de se produire en douceur.
Patent EP-2457550-B8 (EP)
Inventor: REINHARDT ALEX H
IPC: B65B59/00
Filed: 2006-04-26
Granted: 2016-07-13
Abstract: In a preferred embodiment, an automated Pharmacy Admixture System (APAS) may include a manipulator (322) system to transport medical containers such as bags, vials, or syringes in a compounding chamber regulated to a pressure below atmospheric pressure. In a preferred implementation, the manipulator system is configured to grasp and convey syringes (1106), IV bags (1102), and vials (1104) of varying shapes and sizes from a storage system in an adjacent chamber regulated at a pressure above atmospheric pressure. Various embodiments may include a controller adapted to actuate the manipulator system to bring a fill port of an IV bag (1102), vial (1104), or syringe (1106) into register with a filling port at a fluid transfer station in the chamber. A preferred implementation includes a sanitization system that can substantially sanitize a bung on a fill port of a vial (1104) or IV bag in preparation for transport to the fluid transfer station.
Patent BR-PI0721654-B8 (BR)
Title: formas de dosagem sólida compreendendo um revestimento entérico com liberação acelerada do fármaco, seu método de fabricação e uso
Inventor: FANG LIU
IPC: A61K9/50
Filed: 2007-05-07
Abstract: FORMAS DE DOSAGEM SÓLIDA COMPREENDENDO UM REVESTIMENTO ENTÉRICO COM LIBERAÇÃO ACELERADA DO FÁRMACO.  A presente invenção refere-se a uma forma de dosagem sólida que compreende um revestimento um revestimento interno localizado entre um núcleo que contém um ingrediente farmaceuticamente ativo e um revestimento entérico externo; em que o dito revestimento interno compreende um material polimérico aniônico parcialmente neutralizado e pelo menos um ácido carboxílico que tenha 2 a 16 átomos de carbono, seus sais ou misturas do dito ácido e seu sal; em que o dito revestimento externo compreende um material polimérico aniônico que é menos neutralizado que o material do revestimento interno ou que não é neutralizado.
Patent BR-PI0916182-B8 (BR)
Title: Composição de cuidado do cabelo
Inventor: KHOSHDEL EZAT
IPC: A61K8/86
Filed: 2009-12-02
Abstract: composição de cuidado do cabelo. a presente invenção trata de uma composição de cuidado do cabelo compreendendo uma macromolécula dendrítica funcionalizada hidrofobicamente emulsificada.
Patent BR-PI9607851-B8 (BR)
Title: combinação e formulação farmacêutica.
Inventor: DAVID WALTER BARRY
IPC: A61K31/70
Filed: 1996-03-28
Abstract: "combinação que compreende dois compostos, formulação farmacêutica, processo para o tratamento ou a prevenção de sintomas ou efeitos de uma infecção por hiv em uma animal infectado, utilização e embalagem para um paciente". a presente invenção refere-se a combinações terapêuticas de (is,4r)-cis-4-[2-amino06-(ciclopropilamino0-9-h-purin-9-il]-2-ciclopenteno-1-metanol (1592u89), 3'-azido-3'-deoxitimidina (zidovudina) e (2r,cis)-4-amino-1-(2-hidroximetil-1,3-oxatiolan-5-il)-(1h)-pirimidin-2-ona (3tc) (ou, alternativa a 3tc, (2r,cis)-4-amino-5-fluoro-1-(2hidroximetil-1-3-oxatiolan-5-il)-(1h)-pirimidin-2-ona (ftc) que possuem atividade-hiv. a presente invenção também se refere a composições farmacêuticas contendo as referidas combinações, e a seu uso no tratamento de infecçõe por hiv incluindo infecções por mutantes do hiv que apresentam resistência a inibidores de nucleosídeo e/ou inibidores de não-nucleosídeo.
Patent AU-2001237827-B8 (AU)
Title: Radioactive therapeutic liposomes
Inventor: LARSEN ROY H
IPC: A61P35/00
Filed: 2001-02-21
Granted: 2001-08-27
Abstract: The present invention relates to a conjugator system comprising liposomes with ionophores, and with chelator solution and alpha-particle emitting radionuclide(s) located inside of the liposome. Furthermore, a the method for the preparation of this type of radioactive liposomes is described, as well as use of the system and a kit for preparing the system.
Patent AU-2007203150-B8 (AU)
Title: Flexible polymer element as toughening agent in prepregs
Inventor: MCGRAIL PATRICK TERENCE
IPC: C08J5/24
Filed: 2007-07-05
Granted: 2009-08-27
Abstract: A flexible polymer element for a curable composition wherein the flexible polymer element is in solid phase and adapted to undergo at least partial phase transition to fluid phase on contact with a component of the curable composition in which it is soluble at a temperature which is less than the temperature for substantial onset of gelling and/or curing of the curable composition; a method for the preparation thereof, a support structure or carrier for a curable composition comprising the at least one flexible polymer element together with reinforcing fibres, configurations of support structures and carriers, methods for preparation thereof, a curable composition comprising the at least one flexible polymer element or the support structure or carrier and a curable resin matrix, a kit of parts comprising the components thereof and a method for selection thereof, a method for preparation and curing thereof, and a cured composite or resin body obtained thereby, and known and novel uses thereof.
Patent BR-112012001344-B8 (BR)
Title: derivados de 17hidróxi-17-pentaflúoretil-estra-4,9(10)-dieno-11-arila, seus usos, e produto medicinal
Inventor: ANDREA ROTGERI
IPC: A61P5/36
Filed: 2010-07-07
Abstract: derivados de 17hidróxi-17-pentafluoroetilestra- 4,9(10)-dieno-11-arila, método de produção destes e uso destes para o tratamento de doenças. a presente invenção refere-se a derivados de 17-hidróxi-17-pentafluoroetil-estra-4,9(10)-dieno-11-arila da formula i com ação antagonizante do progesterona e a um método de produção destes, ao seu uso para o tratamento e/ou profilaxia de doenças e ao seu uso para a produção de produtos medicinais para o tratamento e/ou profilaxia de doenças, particularmente de fibroides, particularmente de fibroides uterinos (miomas, leiomioma uterino), endometriose, sangramentos intensos menstruais, meningiomas, cânceres de mama hormônio-dependentes e queixas associadas à menopausa ou para controle de fertilidade e contracepção de emergência.
Patent BR-112013022941-B8 (BR)
Title: método para fabricação de glicopeptídeo tendo cadeia de açúcar sialil e método para a fabricação de um derivado de sialilglicoasparagina
Inventor: KAZUYUKI ISHII
IPC: C08B37/00
Filed: 2012-03-05
Abstract: método para fabricação de glicopeptídeo tendo cadeia de açúcar sialil, derivado de aminoácido adicionado de cadeia de açúcar sialil para ser usado no mesmo, e glicopeptídeo para proporcionar um método para a fabricação que permite a obtenção de um glicopeptídeo alvo portador de uma cadeia de açúcar sialil com elevado rendimento sem decomposição do ácido siálico no terminal não redutor da cadeia de açúcar quando o glicopeptídeo é sintetizada por um método de síntese em fase sólida boc. a presente invenção é caracterizada pelo fato de que o derivado de aminoácido boc sialilglicosilado utilizado no método de síntese em fase sólida boc é aquele em que o grupo carboxila do ácido siálico no terminal não redutor da cadeia de açúcar é protegido com um grupo fenacila.
Patent BR-112013023446-B8 (BR)
Title: Equipamento de acionamento para uma ferramenta subterrânea seletivamente operável a partir de uma localização remota
Inventor: ALASDAIR R TAIT
IPC: E21B34/06
Filed: 2012-03-08
Abstract: sistema de ativação remota de ferramenta subterrânea uma ferramenta de acionamento utiliza uma trava que quando liberada permite que um imã móvel se desloque para posição para repelir outro imã. a força de repulsão sobre o segundo imã desloca-o para longe de uma posição de travamento em um sistema de energia potencial armazenada onde a liberação da energia potencial cria energia cinética para mover um mecanismo de acionamento para acionar a ferramenta. em uma aplicação preferida a ferramenta pode ser um mancal de revestimento. o dispositivo de liberação pode ser um eletroímã ou um solenóide seletivamente energizado que desloca ao menos um imã para alinhamento com ao menos um segundo imã de modo a evitar que o segundo imã armazene efetivamente a energia potencial que pode acionar a ferramenta quando a trava for anulada.
Patent BR-112015002918-B8 (BR)
Title: Construção de ácido nucleico compreendeendo uma região não traduzida, vetor e métodos para produção de um peptídeo ou uma proteína e para a expressão de um gene em uma planta ou células vegetais
Inventor: SANDEEP KUMAR
IPC: C12N15/82
Filed: 2013-08-08
Abstract: CONSTRUTO DE ÁCIDO NUCLEICO COMPREENDEENDO UMA REGIÃO NÃO TRADUZIDA, VETOR, USOS DE UMA PLANTA OU CÉLULA VEGETAL E DE PELO MENOS UMA SEQUÊNCIA DE CONTROLE, E MÉTODOS PARA PRODUÇÃO DE UM PEPTÍDEO OU UMA PROTEÍNA, PARA O AUMENTO DA EXPRESSÃO DE UM GENE EM UMA PLANTA OU CÉLULAS VEGETAIS E PARA GERAR UMA PLANTA OU SEMENTE TRANSGÊNICA. São fornecidos processos, vetores e construtos gênicos para aumentar a expressão de uma sequência de ácido nucleico recombinante em plantas e tecidos vegetais transgênicos. De acordo com a presente invenção, as sequências de ácido nucleico são obtidas e/ou derivadas das regiões não traduzidas a 3 de genes que codificam proteínas ubiquitina e engenheiradas para flanquearem as respectivas porções de uma região codificadora selecionada de um vetor. O construto de vetor pode ser introduzido em plantas e/ou tecidos vegetais através de procedimentos convencionais ou de direcionamento gênico, resultando na expressão aprimorada da região codificadora selecionada. Em algumas modalidades, a região codificadora selecionada é um gene quimérico ou um fragmento gênico que expressa uma ou mais proteínas conhecidas por conferirem um nível de atividade inseticida a uma planta e/ou um tecido vegetal transgênico.
Patent BR-112015017023-B8 (BR)
Title: Leitor de cartão inteligente, sistema e dispositivo de cliente
Inventor: JEROME A LAPALME
IPC: G06K7/00
Filed: 2014-02-20
Abstract: LEITOR DE CARTÃO INTELIGENTE,SISTEMA E DISPOSITIVO DE CLIENTE RESUMO. Um leitor de cartão inteligente aperfeiçoado tendo uma fileira de primeiros contatos de leitura, uma fileira de segundos contatos de leitura, e uma fileira de terceiros contatos de leitura. Os primeiros contatos de leitura tendo partes de braço que são suportadas por um primeiro elemento de montagem do leitor, os segundos contatos têm partes de braço que são suportadas por um segundo elemento de montagem do leitor, e os terceiros contatos tendo partes de braço que são suportadas por um terceiro elemento de montagem do leitor. O terceiro elemento de montagem está localizado verticalmente distanciado do segundo elemento de montagem, e as partes de braço dos terceiros contatos de leitura sobrepõem as partes de braço dos segundos contatos de leitura.
Patent DE-102007020938-B8 (DE)
Inventor: WERTHER WOLFGANG
IPC: G01N27/90
Filed: 2007-05-04
Granted: 2009-04-23
Abstract: The invention relates to a device for detecting and monitoring damage to races or adjacent regions of bearing rings (1, 2, 3) of anti-friction bearings. The device includes a measuring device, disposed in the anti-friction bearing chamber, having a sensor and structure for supplying sensor measurement data to the outside. The device has an energy source, which is also disposed in the anti-friction roller bearing chamber and which comprises a first coil (16) for the measuring device and a second coil (18) disposed outside the anti-friction bearing chamber and destined for inductive transfer of electrical energy to the first coil (16). The second coil (18) extends only over a part of the bearing circumference and the energy source comprises an energy accumulator (19) connected to the first coil (16).
Patent DE-10241760-B9 (DE)
Title: Fackel
Inventor: LINKE WOLFGANG
IPC: F42B4/26
Filed: 2002-09-10
Granted: 2005-04-14
Abstract: Fackel,
bestehend aus einem länglichen
brennbaren Materialstück
mit Einschnitten und einer Vertiefung zum Einlegen eines aus einer
brennbaren Substanz bestehenden Anzündkörpers,  gekennzeichnet
durch  a) mindestens drei versetzt angeordnete in Richtung der Längsachse
eines länglichen
brennbaren Fackelkörpers (1)
verlaufende Einschnitte (7) mit in Richtung von der Zündstirnfläche (2)
zur Standstirnfläche
(4) hin linear abnehmender radialer Tiefe und Fackelsegmenten (6),
wobei  b) eine Brennseele (5) durch die Fackelsegmente (6) und die
Einschnitte (7) mit in Richtung von der Zündstirnfläche (2) zur Standstirnfläche (4)
hin linear abnehmender Tiefe im Inneren des länglichen brennbaren Fackelkörpers (1)
begrenzt wird und  c) die Zuführung eines Teiles des zum
Verbrennungsvorgang in dem länglichen
brennbaren Fackelkörper
(1) notwendigen Sauerstoffes über
eine Gitterstruktur (10) der drehbaren Innenstandfläche (9)
der Brandschale (8) realisiert wird.
Patent AU-2008317693-B9 (AU)
Title: Construction method and construction apparatus for offshore wind turbine generator
Inventor: TOMOHIRO NUMAJIRI
IPC: F03D11/04
Filed: 2008-08-28
Granted: 2011-08-25
Abstract: (12) tVE* I)J Ii ~-J L N l DI IH D II M I Ii (19) 011 f -$@$1fi | (43) M, 1 l 10 2010 * 3 fA 4 H (04.03.2010) PCT WO 2010/023743 Al (51) MRZWWFr}: (81) t$IR (5®tL\39, ±T ®f lMO Af B63B 35/00 (2006.01) F03D 11/04 (2006.01) HE f ): AE, AG, AL, AM, AG, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, (21) t1295 3: PCT/JP2008/065396 CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, Fl, GB, (22) M WtRE6E: 2008 Pl 8 J 28 8 (28.08.2008) GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, (25) M W RE0) -11 : 13M LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, (26) =: 6 i MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (71) <A[ (C K 1 Z D I L% \ ): E TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, W 2 ttt A *(MITSUBISHI HEAVY INDUS- ZA, ZM, ZW. TRIES, LTD.) [JP/JP]; T 1088215 1 i (4 t i (A,tL U) 6D®6D ZT fi 1T (f ): ARIPO (BW, GH, GM, KE, LS, MW, MZ, (72) MBA J; iZ NA, SD, SL, SZ, TZ, UG, ZM, ZW), .-L - 5 / 7 (75) BA /-tJA (9 M 2-D L \ -C ) ): iUR %Itd (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM), E - M V/ / (NUMAJIRI, Tomohiro) [JP/JP]; T 8508610 A 0 : (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, Fl, FR, GB, A0f$ MO 0)-AT 1 # 1 -F- E AJ t I t tt GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, A0.J Pfr i Nagasaki (JP). PL, PT, RO, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, (74) It AT: [B E A l, 3 (FUJITA, Takaharu et al.); CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). T2200012 ll k0iiIT Z 4XL o 61 3 - 't f : 3 - 1 ErNEWT1L_)|L2 4 F Kanagawa(JP). - IkiM ($$9 921 (3)) (54) Title: CONSTRUCTION METHOD AND CONSTRUCTION RIG OF FLOATING WIND TURBINE GENERATOR ==(5 4) 59 ®~ B)1):9 T -FLt5 ,N0 13 ARL 4 k4 , - A31 ](57) Abstract: A rig (50) for constructing a floating wind turbine generator (10) smoothly in safety on a deep sea. The rig (50) for constructing a floating wind turbine gen erator (10) by a crane ship (S) comprises a guide member (51) fixed to a vertical work position for the crane ship (S) while locating the lower end side underwater, and at least a pair of arm portions (60) each having a grasping portion to which a tower portion (20) divided into a plurality of Km section in the axial direction can be attached removably 60 (60A) and sliding along the guide member (51). 50 _ Ijt5X R (1 0) /hJ\2xA-Xc L4 -- k*7@ 4 k IRE (5 0) flm t A @ T L R Ks tX4kf ( 1 0 ) / L--'./ ( S ) L) 51-- 51 7@ 4 1 k 4 IN( 5 0 It, ' 1- -'/ >A = (S) -52 - _ - -- tL rapt- P5o 47r- ] 35 60 (60B) 21
Patent AU-2017228252-B9 (AU)
Title: Method and system for providing permissions management
Inventor: LIETZ M SHANNON
IPC: H04L29/06
Filed: 2017-02-24
Granted: 2021-07-01
Abstract: Reference architecture pattern role data representing reference architecture pattern roles to be associated with entities taking part in the development, and/or deployment, and/or operation of an application is generated. Reference architecture pattern tier data representing reference architecture pattern tiers used to create, and/or deploy, and/or operate an application using the reference architecture pattern is generated. For each reference architecture pattern role at least one access and/or operational permission is associated with each reference architecture pattern tier. An entity is assigned one of the reference architecture pattern roles and for each reference architecture pattern tier, the entity is automatically provided the at least one access and/or operational permission associated with the reference architecture pattern role assigned to the entity. When a computing task is requested, permissions associated with the computing task are adjusted based on a risk level associated with performance of the requested computing task.