baber/WOPTO huggingface dataset:
Patent ZA-200402498-B (ZA)
Title: Staurosporne derivatives as inhibitors of flt3 receptor tyrosine kinase activity
Inventor: PAUL WILLIAM MANLEY
IPC: C07D/
Filed: 2004-03-30
Abstract: The present invention relates to the use of staurosporines derivatives for the preparation of a drug for the treatment of diseases involving deregulated FLT3 receptor tyrosine kinase activity, especially for the curative and/or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving deregulated FLT3 receptor tyrosine kinase activity.
Patent ZA-200604528-B (ZA)
Title: Polycyclic agents for the treatment of respiratory syncytial virus infections
Inventor: SILAS BOND
IPC: A61K31/4188
Filed: 2006-06-02
Abstract: Compounds of formula I   
salts, and pharmaceutically acceptable derivatives thereof, wherein: A, together with the atoms to which it is attached, represents an optionally substituted phenyl ring; B-C is an optionally substituted link of the formula -CH 2 -(CH 2 ) z -, where z is 1-4; X and Y are independently selected from O, S and NR 6 , where R 6  is independently selected from hydrogen, C 1-6 alkyl, hydroxy and C 1-6 alkoxy; and R 1  and R 2 ;are as defined herein; are described. The compounds are useful as antiviral agents in particular the treatment of infections involving viruses of the  Pneumovirinae  subfamily.
Patent ZA-200605535-B (ZA)
Title: Apicomlex vaccine strains of a family of Sarcocystidae
Inventor: DUBREMETZ JEAN-FRANCOIS
IPC: A61P/
Filed: 2006-07-05
Abstract: Mutant strain (A) of an Apicomplexa of the family Sarcocystidae contains mutations that inactivate both of the adhesins MIC1 and MIC3. An independent claim is also included for a vaccine that contains (A). ACTIVITY : Protozoacide. MECHANISM OF ACTION : Vaccine. Mice were injected intraperitoneally with 20 tachyzoites of T. gondii in which both MIC1 and MIC3 were inactivated, then 1 month later challenged with 70 cysts of the cystogenic strain 76K. Practically no cerebral cysts were formed in the vaccinated animals (99.9 % protection).
Patent ZA-200707681-B (ZA)
Title: Disposable assembly containing a skin piercing element
Inventor: OGILVY POTTER CHARLES DAVID
IPC: A61M/
Filed: 2007-09-06
Abstract: The invention relates to devices used in the fields of drag delivery or sampling. More particularly, it relates to a disposable assembly which is fitted to an actuator device which causes the skin piercing element to enter the skin to deliver a drug (or other substance) or take a sample. Preferably the assembly is “made safe” after actuation, such that the disposable assembly can't be reused and more preferably still the skin piercing element is safely housed in the assembly such that it does not constitute a “sharps” risk.
Patent ZA-200710875-B (ZA)
Title: Heat exchanger assembly which is intended, in particular, for a high-temperature nuclear reactor
Inventor: ALAIN CROS
IPC: G21C/
Filed: 2007-12-14
Abstract: The invention relates to an assembly for exchanging heat between first and second fluids, the assembly comprising a central manifold communicating with one of the inlet and the outlet for the first fluid; an annular manifold disposed around the central manifold and communicating with the other one of the inlet and the outlet for the first fluid; a plurality of heat exchangers interposed radially interposed between the central manifold and the annular manifold; and a plurality of axial inlet manifolds communicating with the inlet for the second fluid, and a plurality of axial outlet manifolds communicating with the outlet for the second fluid, the axial inlet and outlet manifolds being interposed circumferentially between the heat exchangers. According to the invention, the assembly has an inlet chamber disposed at a first axial end of the heat exchangers and putting the inlet(s) for the second fluid into communication with at least a plurality of axial inlet manifolds.
Patent ZA-200900164-B (ZA)
Title: Cysteine granules and use thereof as bifidobacterium animals lactis growth stimulants
Inventor: MARCHALL LAURENT
IPC: A23C/
Filed: 2009-01-08
Abstract: The present application relates to an inoculum that is particularly suitable for the direct inoculation of at least one stran of Bifidobacterium animalis ssp. lactis in a dairy substrate, for the conversion of said dairy substrate into a fermented dairy product. This inoculum comprises, in mixture or in collection form, the L-cysteine base and at least one strain of B. animalis lactis. Said cysteine and said at least one strain of B. animalis lactis are each contained in, or in the form of frozen and/or lyophilizate granules. Advantageously, said cysteine is incorporated within the same granules or the same lyophilizate as the cells of B. animalis lactis.
Patent GR-1003934-B (GR)
Title: Folding multi-part paperboard casings destined for the transport of improvised food
Inventor: PANAGIOTOPOULOS PANAGIOTIS
IPC: B65D5/36
Filed: 2001-05-07
Abstract: he inventions relates to a folding paperboard food casing having two or three compartments suitable for the protection, transport and consumption of ready-to-eat solid or fluid food. The folding casing in question can be deployed and supported by two "feet" projected from the two lateral small sides of same casing whose base has an arcuated form improving stability. Said casing is destined for use in catering, fast food restaurants, or restaurants of improvised food, in general.
Patent MX-346968-B (MX)
Title: Easy opening packaging article made from heat-shrinkable film exhibiting directional tear.
Inventor: H WALKER STOCKLEY III
IPC: B65D75/00
Filed: 2008-05-20
Abstract: A packaging article has tear initiators for initiating a manual tear that can be propagated to open a package and allow a product to be readily removed therefrom, without the use of a knife or scissors or any other implement. The packaging article is made from a heat-shrinkable multilayer film having at least one layer containing an incompatible polymer blend, and/or a layer containing an inorganic filler, and/or a layer having a high Young's modulus. The film also has a Peak Load Impact Strength of at least 50 Newtons per mil, The tear initiators can be used to generate a manual machine direction tears to open the package, with the manual machine direction tear being capable of propagating in the machine direction to the opposite edge of the packaging article. A process for making a package and manually opening the package is also disclosed.
Patent MX-338125-B (MX)
Title: Telescopic needle shield with interlock.
Inventor: BRIMHALL GREG L
IPC: A61M5/32
Filed: 2009-03-12
Abstract: A needle shield system includes a needle (28), an inner tube (24), a clip (26) within the inner tube, an outer tube (22), and/or a housing. A method of shielding a needle may include housing a portion of a needle within a clip, housing the clip within an inner tube, housing the inner tube within an outer tube, housing the outer tube within a housing, interlocking the outer tube and the housing, withdrawing the needle from the clip, trapping a tip of the needle between the clip and the inner tube, partially withdrawing the inner tube from the outer tube, and/or releasing the outer tube and the housing from each other.
Patent MX-345078-B (MX)
Title: Air filter cartridge and air cleaner assembly.
Inventor: THOMAS G MILLER
IPC: B01D46/52
Filed: 2007-07-13
Abstract: An air filter arrangement is disclosed. The air filter arrangement includes strips of media comprising fluted sheets secured to facing sheets and forming inlet and outlet flutes secured to one another in a stack. Media pack arrangements including such stacked media with peripheral, perimeter, housing seal arrangements are described. Also described are air cleaners including the filter cartridges. Methods of assembly and use are also provided. Also, systems of use are described.
Patent MX-340830-B (MX)
Title: Pneumococcal vaccine and uses thereof.
Inventor: DAVIS HEATHER LYNN
IPC: A61K39/09
Filed: 2010-03-17
Abstract: The present invention relates to new pneumococcal vaccines. The invention also relates to vaccination of subjects, in particular immunocompromised subjects, against pneumoccocal infections using said novel pneumococcal vaccines.
Patent MX-360640-B (MX)
Title: Cancer diagnosis and imaging.
Inventor: LLOYD S GRAY
IPC: A61B5/055
Filed: 2011-02-28
Abstract: The present invention provides a method for imaging a disease or condition in a mammal which includes the steps of; administering a therapeutically effective amount of a cell cycle inhibitor to effectively stop proliferation of eukaryotic cells at a cell cycle checkpoint between the G1 and S phase, stopping administration of the cell cycle inhibitor for a period of time, administering a marker to the mammal and imaging the mammal.
Patent MX-363662-B (MX)
Title: Method for increasing the sensitivity to insulin by 5-ht2 receptor antagonists.
Inventor: ENRIQUE HONG CHONG
IPC: A61K31/4035
Filed: 2012-10-08
Abstract: The present invention refers to the participation of 5-HT2 serotonergic receptor with an increased insulin sensibility, mainly caused by the peripheral capture of glucose. The present invention is intended to use 5-HT2 receptor antagonist, such as indorrenate (hypertensive agent acting as central 5-HT1A receptor agonist) in pharmaceutical compositions for improving the insulin sensitivity, upon acting as 5-HT2 agonist in the periphery.
Patent MX-338225-B (MX)
Title: Organotin compounds derived from urocanic acid with antitumor activity.
Inventor: CAMACHO CARLOS CAMACHO
IPC: A61K31/40
Filed: 2012-10-24
Abstract: The present invention refers to the preparation of novel derivatives of urocanic acid: tri-n-butyltin (IV) carboxylate and triphenyltin (IV) carboxylate, compounds which formulas are [(C6H5N202) Sn (CH2CH2CH2CH3)3](I) and [(C6H5N2O2)Sn(C6H5)3] (II) respectively. Where the compounds coordinated with tin are formed by the reaction between an organotin and 4-imidazolacrylic acid (urocanic acid) by means of a process that includes the preparation of a reactant mixture, the synthesis by reflux and the mixture and purification of the derivatives by recrystallization. The novel derivatives present antitumor activity in vitro against the growth of cancer cells of human origin: U251 (glia of central nervous system), PC-3(prostate), K562 (leukemia), HTC-15 (colon), MCF-7 (breast) and SKLU (lung).
Patent MX-339276-B (MX)
Title: Process for preparing polyurea microcapsules.
Inventor: STRUILLOU ARNAUD
IPC: A61Q13/00
Filed: 2011-06-07
Abstract: The present invention relates to a process for producing perfume-containing microcapsules with a polyurea wall that can be used in home or personal care products, as well as to the microcapsules themselves and consumer products comprising these microcapsules. The process of the invention uses a combination of aromatic and aliphatic polyisocyanates in specific relative concentrations.
Patent MX-359007-B (MX)
Title: Rubber wiper blade for windscreen wiper of vehicle, has base body comprising surface structure with projections, and strong hydrophobic layer formed between projections such that projections protrude from hydrophobic laye.
Inventor: YVES VERBURGH
IPC: B05D5/08
Filed: 2013-02-08
Abstract: The blade (10) has a base body (1) comprising a surface structure with projections, which are randomly distributed on a micrometer scale. A strong hydrophobic layer (3) is formed between the projections such that the projections protrude from the hydrophobic layer. The hydrophobic layer is formed from a polymer containing silicon and a silicon compound. The projections include particles (2) bonded to a surface of the base body. The particles contain a material that is selected from a group consisting of carbon black, silicates, metal oxides and/or metals or metal alloys. The silicon compound is selected from a group consisting of silicone oils, polysiloxanes, copolymers of polysiloxane, polysilanes, polysilane copolymers and from a polysiloxanes functionalized vinyl group and functionalized polysiloxane amino group and organo-alkoxysilane. Independent claims are also included for the following: (1) a method for manufacturing a rubber wiper blade (2) a wiping scraper.
Patent MX-343419-B (MX)
Title: Drying process.
Inventor: YVES MAYERESSE
IPC: C12N1/04
Filed: 2003-10-30
Abstract: The present invention relates to a method of drying biological and other labile samples so that they can be preserved as a highly viscous liquid. The method involves the steps of preparing a preservation sample by dissolving/suspending an active agent in a solution of a stabilising agent, subjecting the preservation sample to such temperature and pressure conditions that the preservation sample looses solvent by evaporation without freezing or bubbling to form a foam and removing solvent until the preservation sample dries to form a highly viscous liquid.
Patent MX-364560-B (MX)
Title: Microencapsulation process and product.
Inventor: CECIL W PROPST
IPC: A61K9/20
Filed: 2011-09-20
Abstract: A composition comprising a core material, having a taste value and a polymeric coating. The polymeric coating substantially surrounds the core material and comprises a cationic polymer and optionally an anionic polymer. The polymeric coating has a uniform thickness ranging from 2 µm to 20 µm. The composition provides release of a portion of the core material which is taste masked over a time period ranging from 0.5 minute to 2 minutes in the oral cavity and provides a modified-release of the remaining core material in a gastrointestinal tract.
Patent MX-353867-B (MX)
Title: Coating compositions with improved adhesion to containers.
Inventor: MICHAEL LIST
IPC: C08G59/30
Filed: 2012-05-22
Abstract: A coating composition comprising a resinous binder and up to 10 percent by weight of the reaction product of (i) a phosphorus acid, and (ii) a polyglycidyl ether of cyclohexane dimethanol. The compositions are useful for coating containers of all sorts, such as food and beverage containers, and the reaction product provides enhanced adhesion of the coating to the substrate. The compositions can be formulated to be substantially free of bisphenol A (BPA) and derivatives thereof such as bisphenol A diglycidyl ether (BADGE).
Patent MX-346794-B (MX)
Title: Novel crystalline acid addition salt of tricyclo derivative compound or hydride thereof, and production method therefor.
Inventor: IN-HAE YE
IPC: A61K31/5377
Filed: 2013-01-28
Abstract: The present invention relates to a novel crystalline acid addition salt of a tricyclo derivative compound or a hydride thereof, and to a production method therefor. The crystalline acid addition salt or the hydride thereof according to the present invention is stable with respect to moisture and consequently stable with respect to hygroscopicity and so is very useful in maintaining quality when producing a drug, and, in addition, can be used to advantage as a pharmaceutical composition for treating neuropathic pain, epilepsy, stroke, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, schizophrenia, chronic and acute pain, ischemic brain injury, neuronal loss after hypoxia, trauma and nerve damage, which are medical conditions induced by PARP (poly (ADP-ribose) polymerase) overactivity.
Patent MX-355435-B (MX)
Title: Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof.
Inventor: SUNIL KUMAR KC
IPC: A61P19/00
Filed: 2013-03-13
Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. One embodiment disclosed herein includes a compound having the structure of Formula I:.
Patent MX-360993-B (MX)
Title: Pwm data processing method and device.
Inventor: YI DING
IPC: G08C23/04
Filed: 2015-01-30
Abstract: Disclosed in the present disclosure are a Pulse-Width Modulation (PWM) data processing method and a device. The present disclosure is used for reducing the quantity of learned PWM data. The method includes the steps: a convergence point pulse width of the pulse widths converged around the same pulse width in the learned PWM data is determined; the pulse widths converged around the same pulse width are replaced by the convergence point pulse width; a pulse width query table containing the convergence point pulse width is generated; the PWM data is represented by the use of the index of the pulse widths in the pulse width query table. By means of the technical solution, the quantity of the PWM data is reduced, the PWM data transmission speed is increased, and the space required for storing the PWM data is reduced. Disclosed in the present disclosure are a Pulse-Width Modulation (PWM) data processing method and a device. The present disclosure is used for reducing the quantity of learned PWM data. The method includes the steps: a convergence point pulse width of the pulse widths converged around the same pulse width in the learned PWM data is determined; the pulse widths converged around the same pulse width are replaced by the convergence point pulse width; a pulse width query table containing the convergence point pulse width is generated; the PWM data is represented by the use of the index of the pulse widths in the pulse width query table. By means of the technical solution, the quantity of the PWM data is reduced, the PWM data transmission speed is increased, and the space required for storing the PWM data is reduced. Disclosed are a waterproof and oxygen-insulation sealing film, and a preparation method and use thereof. Graphene oxide nanoribbons (GONRs) are firstly prepared by a method for longitudinal oxidative cutting of multiwalled carbon nanotubes and modified to obtain functional graphene oxide nanoribbons (K-GONRs), and then the K-GONRs are composited with an ethylene-vinyl acetate copolymer (EVA) in a film coating machine to form a film. In the composite thin film prepared by the present invention, the compatibility of the K-GONRs and the EVA matrix is very good; at the same time, the K-GONRs achieve a good dispersion in the matrix. In addition, the obtained sheet-like K-GONRs are mostly distributed in the EVA composite thin film in parallel. Such a multilayer and parallelly distributed special structure and a close combination of K-GONRs intercalation layers with the EVA matrix enable this thin film to have excellent barrier properties, good acid and alkali resistance, and further improved mechanical properties; meanwhile, this thin film is safe and environmentally friendly, is especially suitable for preparation of sealing films for expensive precise instruments, ice bags for packaging ice and frozen products, and food package films, and has a broad practical application value.
Patent MX-352562-B (MX)
Title: Methods for whitening teeth.
Inventor: SUMAN CHOPRA
IPC: A61Q11/00
Filed: 2012-12-14
Abstract: Described herein are regimens for whitening teeth, comprising administering to the teeth an effective amount of a first oral care composition comprising a bleaching agent and allowing the first oral care composition to remain on the teeth for at least 30 seconds, and brushing the teeth with a second oral care composition. Kits comprising a first oral care composition comprising a bleaching agent, wherein said first oral care composition is adapted to remain on said tooth for at least 30 seconds; a second oral care composition; and instructions for use, are also provided.
Patent MX-360860-B (MX)
Title: Three-part end cap and filter element including same.
Inventor: TIMOTHY L KRULL
IPC: B01D29/96
Filed: 2013-12-27
Abstract: A multi-component end cap is provided. The multiple components combine to form one or more seal carriers where each seal carrier is formed in part by at least two different ones of the components. Methods of manufacturing an end cap having multiple components are also provided.
Patent MX-355193-B (MX)
Title: Three-dimensional waven corner fitting with lap joint performs.
Inventor: JONATHAN GOERING
IPC: D03D25/00
Filed: 2013-12-04
Abstract: A three-dimensional corner lap joint preform and a method of forming a three- dimensional corner lap joint preform including a woven flange with one or more legs that extend from the flange. The legs may include one or more independently woven portions which allow formation of a corner without darting the leg or adding additional reinforcement. The independently woven portions may include warp fibers which are not woven into the preform. The unwoven area al lows removal of a portion of the leg prior to formation of the corner, allowing the portions of the leg to overlap and form a lap joint.
Patent MX-358727-B (MX)
Title: Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one specific amide compound.
Inventor: ANGELINA ROUDOT
IPC: A61K8/41
Filed: 2014-01-20
Abstract: The present invention relates to a cosmetic or dermatological composition comprising, in a physiologically acceptable support: a) at least one merocyanine of formula (1) or (2). b) at least one oily phase comprising at least one amide compound of formula (I). The present invention also relates to a non-therapeutic cosmetic process for caring for and/or making up a keratin material, comprising the application, to the surface of the said keratin material, of at least one composition as defined above. The invention also relates to a non-therapeutic cosmetic process for limiting the darkening of the skin and/or improving the colour and/or uniformity of the complexion, comprising the application, to the surface of the keratin material, of at least one composition as defined previously. The invention also relates to a non-therapeutic cosmetic process for preventing and/or treating the signs of ageing of a keratin material, comprising the application, to the surface of the keratin material, of at least one composition as defined previously.
Patent MX-367621-B (MX)
Title: Genetic polymorphisms in age-related macular degeneration.
Inventor: GRAHAM ROBERT
IPC: C12Q1/68
Filed: 2010-10-20
Abstract: The application relates to methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from treatment with a high-affinity anti-VEGF antibody.
Patent MX-366906-B (MX)
Title: Purification of iduronate-2-sulfatase.
Inventor: NICHOLS DAVE
IPC: A61K38/095
Filed: 2013-06-28
Abstract: The present invention provides, among other things, improved methods for purifying 12 S protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant I2S protein can be purified from unprocessed biological materials, such as, I2S-containing cell culture medium, using a process involving as few as four chromatography columns.
Patent MX-366102-B (MX)
Title: Filmless backsheets with good barrier properties.
Inventor: JILL M MARTIN
IPC: B32B3/00
Filed: 2014-10-22
Abstract: A multilayer nonwoven structure is described where the nonwoven structure comprises at least two spun bond layers and at least one easily meltable layer. The easily meltable layer is located between the at least two spunbond layers. The easily meltable layer is comprised of a polymer having a melting point at least 20°C less than the melting point of the polymer which comprises the surface of the fibers which comprise the spun bond layer, or is made from a polymer which is readily absorbs some form of radiation. Under bonding conditions, the fibers which make up the easily meltable layer can be melted to form a film, thereby improving barrier properties of the nonwoven structure.