baber/WOPTO huggingface dataset:
Patent PT-1302468-E (PT)
Title: Processes and intermediates for manufacturing retroviral protease inhibiting compounds
Inventor: COOPER ARTHUR J
IPC: C07D233/84
Filed: 1993-12-16
Abstract: A retroviral protease inhibiting compound of formula (A) is disclosed for use in combination with other active pharmaceutical agents for treating a human infected by HIV. Intermediates and processes useful in the manufacture of compounds of formula (A) are also disclosed. <CHEM>
Patent PT-1733385-E (PT)
Title: Recording medium and method and apparatus for reproducing and recording text subtitle streams
Inventor: SEO KANG SOO
IPC: H04N5/775
Filed: 2005-03-03
Abstract: A recording medium and method and apparatus for reproducing and recording at least one text subtitle stream, comprising: the text subtitle stream including a dialogue style segment and at least one dialogue presentation segment, the dialogue style segment defining at least one region style to be applied to an overall region of dialogue text, the dialogue presentation segment containing at least one region of dialogue text, the region of dialogue text being linked to one of the at least one region style, the dialogue presentation segment including region subtitle for the region of dialogue text, the region subtitle including a text string and at least one inline style to be applied to a portion of the text string, the inline style for changing at least one of region presentation properties specified by the linked region style for the text string, wherein the region subtitle further including a data type field specifying a type of data immediately following the data type field, the type of data is one of the text string or the inline style.
Patent PT-1726046-E (PT)
Title: Electric energy generating modules with a two-dimensional profile and method of fabricating the same
Inventor: FISCHER DIEGO
IPC: H01L31/048
Filed: 2005-03-16
Abstract: An electric energy generating module is shaped to take on a desired two dimensional profile to match a non-flat surface or architectural element such as corrugated roofing. The module includes an electric energy generating film sealed between a top layer of encapsulant material and a bottom layer of encapsulant material. The type and quantity of the encapsulant materials are such that the shape of the encapsulant materials can be altered when a high temperature and/or pressure is applied to the module, but where the encapsulant materials provide a rigid structure around the electric energy generating film under ordinary (i.e., naturally occurring) temperature and pressure conditions. The module can therefore be shaped by applying a suitable pressure and/or a high temperature but, once placed under ordinary temperature and pressure conditions, the module has a rigid structure.
Patent PT-1769155-E (PT)
Title: Turbine rotor disk with reduced leakage of servo oil
Inventor: HERRMANN CARSTEN DIEDRICH
IPC: F03B3/14
Filed: 2005-06-06
Abstract: Due to increasing environmental requirements, oil must be prevented from leaking from a turbine rotor disk and reaching the medium circulating around the turbine. In Kaplan turbines comprising a hydraulic mechanism (6) for actuating the rotor disk blades (3), hydraulic liquid leaks from the servomotor (5) and is collected in the inner chamber of the rotor disk hub (2). The invention relates to a rotor disk (1) by which means said leakage liquid can be reliably and easily collected and guided out of the rotor disk (1). A collecting basin (8) is arranged-around the free end of the piston rod (7). The actuating movement of the servomotor (5) reduces and enlarges the pump volume (17), and hydraulic liquid is thus guided from the collecting basin (8) into the delivery pipe (11).
Patent PT-1994861-E (PT)
Title: Display rack for self-service sale, in particular for dairy products, adaptable for refrigerated cabinets
Inventor: SERVOZ THIERRY
IPC: A47F5/10
Filed: 2008-05-19
Abstract: The pack (1) has vertical partitions (4) spaced with respect to each other in an adjustable manner, and shelves (7) mounted between the partitions. The partitions delimit vertical modules between them, where the pack is mounted in a movable manner on a base panel of a refrigerated cabinet between two lateral panels of the cabinet. Each shelf is supported by cleats (8'), mounted in a movable manner, at a chosen height, on a rear vertical edge (9') of corresponding partition through lateral slits (16') of the cleats formed on top of the rear edge.
Patent PT-2111555-E (PT)
Title: Diagnosis of preeclampsia
Inventor: HANSSON STEFAN
IPC: A61K38/42
Filed: 2008-02-12
Abstract: The present invention relates to biomarkers for preeclampsia as well as treatment of this disease. In particular, the invention relates to methods for diagnosis or aiding in the diagnosis of preeclampsia of a pregnant female mammal to detect elevated levels of free haemoglobin, particularly free fetal haemoglobin. This facilitates and makes possible early diagnosis and clinical intervention when a preeclamptic condition is found. In addition, the invention relates to a method to treat female mammals with preeclampsia with the purpose to reverse the pathological conditions associated with this disease.
Patent PT-2480232-E (PT)
Title: Disubstituted ]4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones
Inventor: CHOI-SLEDESKI YONG-MI
IPC: A61P19/02
Filed: 2010-08-18
Abstract: The present invention extends to a compound of formula I: or a pharmaceutically acceptable salt of said compound, or a pharmaceutical composition comprising the compound of formula I and a pharmaceutically acceptable carrier. The invention is also directed to the use of a compound of formula I as an inhibitor of tryptase and for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by an inhibitor of tryptase. The invention further includes methods for the preparation of a compound of formula I.
Patent PT-598359-E (PT)
Inventor: INAMASU MASANORI
IPC: A61K31/70
Filed: 1993-11-12
Abstract: A hypoglycemic agent which comprises as an active ingredient a dihydrochalcone derivative of the formula [I]: <CHEM> wherein Ar is an aryl group, R<1> is hydrogen atom or an acyl group, R<2> is hydrogen atom, an acyl group or  alpha -D-glucopyranosyl group, or R<1> and R<2> may combine together to form a substituted methylene group, R<3> and R<4> are each hydrogen atom or an acyl group, and a group of the formula: OR<5> is a protected or unprotected hydroxy group or a lower alkoxy group, or a pharmaceutically acceptable salt thereof.
Patent PT-734389-E (PT)
Inventor: COTTENS SYLVAIN
IPC: A61K31/436
Filed: 1994-12-16
Abstract: PCT No. PCT/EP94/04191 Sec. 371 Date Jun. 14, 1996 Sec. 102(e) Date Jun. 14, 1996 PCT Filed Dec. 16, 1994 PCT Pub. No. WO95/16691 PCT Pub. Date Jun. 22, 1995Novel demethoxy derivatives of rapamycin are found to have pharmaceutical utility, particularly as an immunosuppressants.
Patent PT-793667-E (PT)
Inventor: SPINELLI SILVANO
IPC: C07F15/00
Filed: 1995-11-13
Abstract: PCT No. PCT/EP95/04455 Sec. 371 Date Jul. 25, 1997 Sec. 102(e) Date Jul. 25, 1997 PCT Filed Nov. 13, 1995 PCT Pub. No. WO96/16068 PCT Pub. Date May 30, 1996The present invention relates to trinuclear cationic platinum complexes with alkylene diamine groups connecting the three platinum moieties. The invention also relates to the antitumor activity of these complexes as well as the processes for the preparation thereof and pharmaceutical compositions containing them.
Patent PT-863887-E (PT)
Inventor: ROBIN JEAN-PIERRE
IPC: A61K31/337
Filed: 1996-10-25
Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Patent PT-868428-E (PT)
Inventor: NORCINI GABRIELE
IPC: A61K31/00
Filed: 1996-11-11
Abstract: Compounds of formula (I) wherein R is an alkyl, aryl or arylalkyl group wherein the aryl is phenyl naphthyl or heterocycle; R1 and R2, the same or different, are hydrogen atoms or alkyl groups; R3 is an aryl or arylalkyl group wherein the aryl is as above; R4 is a heterocycle optionally substituted with a heterocycle or phenyl, or it is a phenyl group substituted with a heterocycle (R4 is not imidazole or indole); X is a bond or -OCONH or -CONH- group, processes for their preparation and pharmaceutical compositions thereof, are described. The compounds of formula (I) are endowed with a dual ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular disease.
Patent PT-802539-E (PT)
Inventor: FRIEDMAN HERBERT
IPC: B65D85/57
Filed: 1992-10-22
Abstract: A storage package (10) for a compact disc or the like has a plurality of non-plastic panels (12) including a pair of end panels (12a,12c) and, optionally, at least one panel (12b) intermediate to and connecting the pair of end panels. The plurality of panels (12) is movable between an open orientation (Fig. 2) enabling access to the contents of the package and a collapsed orientation for storage purposes, each of the panels having a pair of opposed lateral sidewalls (19), and the plurality of panels in the collapsed orientation defining at least one spine (32,34). A holder (14) formed of plastic is disposed on one (12b) of the panels for receiving and maintaining a compact disc thereon. An end cap (16) is disposed on one of the end panels or pivotally on the holder (14), the end cap being adapted to releasably engage the holder when the plurality of panels (12) is in the collapsed orientation, thereby to preclude accidental movement of the plurality of panels out of the collapsed orientation. <IMAGE>
Patent PT-874699-E (PT)
Inventor: HEUFT BERNHARD
IPC: G01N21/90
Filed: 1997-01-20
Abstract: In order to inspect objects (10), particularly drinks bottles, these are transported on two conveyors (12, 14), which exhibit a mutual lateral separation and run at different speeds, so that the objects (10) rotate about their vertical axis. Within the distance separating the conveyors (12, 14) a bottom checking installation (30, 32) is provided. A rail (16) for guiding the objects (10) can be arranged, stretching in the direction of transport above the first, slower-running conveyor (12), in such a way that the objects (10) on the first conveyor (12) stand on the edge strip between the rail (16) and the edge of the first conveyor (12), and the width of this edge strip amounts to up to about ⅓ of the diameter of the objects.
Patent PT-927043-E (PT)
Title: Compositions for gene transfer to the central nervous system
Inventor: CHERSKEY BRUCE
IPC: A61P35/00
Filed: 1997-04-07
Abstract: The present invention relates to a method for implanting producer cells into the mammalian brain. The producer cells are engineered with a retroviral based recombinant vector encoding a tumorcidal factor or susceptibility factor that confers on tumor cells sensitivity to chemotherapeutic or radiotherapeutic agents. Prior to transplantation into the mammalian brain, the producer cells are first cultured in vitro on a support matrix to increase the long-term viability of the transplanted cells and to provide long-term functional benefit.
Patent PT-909171-E (PT)
Inventor: SIMONE CLAUDIO DE
IPC: A61P5/06
Filed: 1997-05-15
Abstract: PCT No. PCT/IT97/00113 Sec. 371 Date Jan. 4, 1999 Sec. 102(e) Date Jan. 4, 1999 PCT Filed May 15, 1997 PCT Pub. No. WO98/01128 PCT Pub. Date Jan. 15, 1998A method is provided for increasing the levels of IGF-1 for the therapeutic treatment or prophylaxis of cytological disorders or diseases related to IGF-1 selected from the group consisting of neuropathies of the optic nerve and of the olfactory nerve, neuralgia of the trigeminal nerve, Bell's paralysis, amyotrophic lateral sclerosis, osteoporosis, arthropathy, arthritis, cervical spondylosis and hernia of the intervertebral discs, clinical syndromes of reduced height, cachexia and acute or chronic hepatic necrosis, Turner's syndrome, sarcopoenia, growth hormone insensitivity syndromes, obesity, asthenia, myasthenia and heart asthenia, immunodeficiencies and reperfusion injuries, and for the cicatrization of wounds, the healing of ulcers, the treatment of burns, tissue regeneration, cutaneous, intestinal and hepatic tissue regeneration and the formation of dentine, that includes administering, to a patient in need thereof, at least one selected from the group consisting of L-acetylcarnitine, L-isovalerylcarnitine, and L-propionylcarnitine or pharmacologically acceptable salts thereof.
Patent PT-982420-E (PT)
Inventor: GUSE ROLF
IPC: D03C3/40
Filed: 1999-07-03
Abstract: A coupling device for the releasable connection of a lifting element, in particular of a jacquard machine, to at least one lifting element of a warp thread in a weaving machine. The preferred coupling device connects a sinker cord of a jacquard machine to a harness cord of the harness of a weaving machine. The coupling device has a first coupling part assigned to the lifting element and a second coupling part assigned to the harness cord. The coupling parts execute a radial relative movement during coupling and uncoupling. The coupling device provides for rotational alignment of the two coupling parts with one another. At least one coupling part is assigned or capable of being assigned a rotational alignment mechanism. The coupling device is used in a system which rapidly connects and disconnects many connectors at the same time. The system includes a positioning mechanism for vertically moving two positioning elements which operate the coupling devices between standby and operative positions, and for horizontally moving at least one of the positioning elements to cause the coupling parts of each coupling device to interlock and disengage. The positioning elements also cooperate with portions of at least one of the coupling parts to rotationally align the coupling parts so they may interlock.
Patent PT-1133366-E (PT)
Inventor: TUNDAL ULF
IPC: C21D9/00
Filed: 1999-11-19
Abstract: Apparatus for cooling billets (9), preferably formed of aluminum. The apparatus includes a housing (2) provided with openings (3) for axial passage of the billet through the housing, a cooling ring (4) arranged inside of the housing, and supply lines (6) for supplying a cooling medium to the housing. The cooling medium is supplied to the billet (9) in order to achieve uniform cooling, i.e. cooling without a temperature gradient, around the entire circumference of the billet. The apparatus is capable of rotating the billet while the cooling medium is supplied uniformly around the circumference of the billet (90).
Patent SG-31694-G (SG)
Title: Improved additives for hydraulic cement compositions
Inventor: WEIGAND WILLIS A
IPC: C04B24/10
Filed: 1994-03-01
Abstract: The present invention provides additives for hydraulic cement compositions, particularly masonry cements, which improve the water-repellancy, workability, and board life of said compositions. The additives of the invention comprise a water-insoluble, water-repelling acid, a set retarding composition, an emulsifier, and a polymer selected from the group consisting of polyvinyl alcohol, polyvinyl acetate, hydroxypropyl substituted polysaccharides, and mixtures thereof.
Patent IE-800207-L (IE)
Title: Ophthalmic composition
IPC: A61K9/06
Filed: 1980-02-01
Abstract: Although carbonic anhydrase inhibitors (C.A.I.) can be administered systemically by oral or intravenous routes, attempts to administer them topically have been ineffective and inactive in the treatment of intraocular hypertension. The alkali metal salts, especially the sodium and potassium salts, of salt-forming carbonic anhydrase inhibitors in combination with S-(-)-1- (tert-butylamino) -3-[(4-morpholino-1,2,5-thiadiazol -3-yl)oxy] -2-propanol or its racemic modification are now found to be remarkably effective in lowering intraocular pressure, even in normotensive hosts, but especially in those hosts having an elevated intraocular pressure.
Patent IE-840497-L (IE)
Title: Polymeric compositions¹¹on at least two vinyl chloride polymers
IPC: C08L27/06
Filed: 1984-03-01
Abstract: For the contracting : BE, CH, DE, GB, IT, LI, LU, NL, SE. 1. Polymer composition capable of yielding plastisols and organosols producing, by means of a coating operation, coatings having a matt surface appearance, the said composition comprising at least two vinyl chloride polymers and being characterized in that the said polymers are dispersion resins whose pregelling temperatures differ 30 degrees C and in which the weight ratio of the resin whose pregeling temperature theta 1  is the higher to the resin whose pregeling temperature theta 2  is the lower is between 0,7 and 9 and preferably between 2 and 5. For the contracting State AT 1. Process for the preparation of a polymer composition capable of yielding plastisols and organosols producing, by means of a coating operation, coatings having a matt surface appearance, the said composition comprising at least two vinyl chloride polymers, the said polymers being dispersion resins whose pregeling temperatures differ from each other by at least 20 degrees C and preferably at least 30 degrees C and in which the weight ratio of the resin whose pregeling temperature theta 1  is the higher to the resin whose pregeling temperature theta 2  is the lower is between 0,7 and 9 and preferably between 2 and 5, the said composition being in the form of a mixture of the said resins, process according to which a spray-drying operation is carried out on each of the latices of the said resins, followed by an operation of grinding the polymer agglomerates thus formed and placing the resins obtained in a silo, the said process being characterized in that the spraydrying operations of the said latices are performed in the same apparatus, separately and alternately, and that the resins obtained are placed in the same silo.
Patent IE-830556-L (IE)
Title: Process for preparing 3-alpha,7-beta-dihydroxy-5-beta-¹cholanic acid
IPC: C07J9/00
Filed: 1983-03-15
Abstract: Process to reduce stereoselectively 3alpha-hydroxy-7-keto-5beta-cholanic acid to 3alpha,7beta-dihydroxy-5beta-cholanic acid in ter.alcohols by using, as reducing agent, sodium metal in the presence of other metal salts. Examples of metal salts particularly useful are: potassium, cesium and rhubidium organic salts and, more particularly, potassium acetate or potassium ter.butylate.
Patent IE-880786-L (IE)
Title: Inhibitors of interleukin-1-release
IPC: A61K31/12
Filed: 1988-03-16
Abstract: Methods useful for inhibiting the release of Interleukin-1 and for alleviating interleukin-1 mediated conditions, such as IL-1-mediated inflammation, comprising administration of an effective amount of an alkylidenedithiobis(substituted)phenol, preferably, 4,4'-(isopropylidenedithio)bis(2,6-di-tert-butyl) phenol), generically known as probucol.
[EP0292660A2]
Patent IE-840930-L (IE)
Title: A rasp handle.
IPC: A61B17/16
Filed: 1984-04-13
Abstract: A rasp handle (10) has an elongate body portion (12) with a pistol-type grip (14) extending therefrom and rasp retaining structure (16) at its front end. Such structure (16) includes a fixed jaw (22) and a slide jaw (24) constructed and arranged for sliding movement relative to the fixed jaw (22) between a forward closed locking position where a rasp (44) is locked between the jaws (22,24) and a rearward open rasp receiving and releasing position. A lever (26) is connected to shift the slide jaw (24) between its closed and open positions. A pivot (28) interconnects the lever (26) and the slide jaw (24) so that the lever (26) is free to move between a locked position adjacent the body portion (12) and an unlocked jaw manipulating position away from the body portion (12).
Patent FI-831146-L (FI)
Inventor: PRINCE ALFRED MAYER
IPC: A61K35/16
Filed: 1983-04-05
Abstract: A mammalian blood plasma or plasma derivative substantially free of active hepatitis B or non-A, non-B viruses is disclosed, the plasma being characterized by the presence of factor VIII, the percent by weight of denatured factor VIII to the sum of undenatured factor VIII and denatured factor VIII being less than 50%. The plasma is sterilized by contact with a detergent, alcohol or ether, preferably a mixture of detergent and ether, usually followed by removal of the viral sterilizing agent.
Patent IE-43301-L (IE)
Title: Process for producing tertiary alkyl ethers
IPC: C07C41/05
Filed: 1975-05-15
Abstract: 1506312 Tertiary alkyl ethers SNAMPROGETTI SpA 13 May 1975 [21 May 1974] 20209/75 Heading C2C A tertiary alkyl ester is produced by reacting an alcohol with an olefin having a carboncarbon double bond on a tertiary carbon atom in the presence of an ion-exchange resin in atleast two stages, whereinin one stage the alcohol is present in excess and in another stage the olefin is in excess. The reaction may be carried out using two reactors; all of one reactant is fed to one reactor while all or part of the other reactant is fed to the other reactor, and reaction products are at least in part circulated from one reactor to the other. The invention is exemplified by the reaction of isobutene in a mixed olefin stream with methanol to form methyl tertiary butyl ether. A suitable apparatus is described. Reference has been directed by the Comptroller to Specification 1,176,620.
Patent IE-39684-L (IE)
Title: Package for fragile objects
IPC: B65D85/32
Filed: 1973-08-14
Abstract: A package for fragile objects, especially eggs, consisting of a container part and a cover part flexibly joined thereto, one of the parts comprising a number of pockets for the accomodation of the said objects, the pockets being arranged in at least two parallel rows, and supporting projections provided between the rows of pockets, while the other part has recesses corresponding to the said rows of pockets, and counter-projections between the recesses, that rest on the projections of the first part when one part is closed on the other, the counter-projections at their free ends being provided with a shoulder externally surrounding the supporting areas of the said projections.
[US3920178A]
Patent IE-831436-L (IE)
Title: 1,2,4 - triazole derivatives
IPC: C07D249/08
Filed: 1983-06-17
Abstract: Triazole antifungal agents of the formula:- 
<CHEM>
 and their O-esters and O-ethers;
 where R is naphthyl, biphenylyl or phenyl optionally substituted by 1 to 3 substituents each independently selected from halo, CF3, C1-C4 alkyl and C1-C4 alkoxy; and R<1> is
 -@NR<2>R<3>

 or -@R<3>

 where X is O or S;
 R<2> is hydrogen of C1-C4 alkyl; and
 R<3> is hydrogen, C1-C4 alkyl, C3-C6 cycloalkyl, aryl, aralkyl, or heteroaryl; or
 R<2> and R<3> taken together with the N atom to which they are attached represent a 1-pyrrolidinyl or piperidino group; and their pharmaceutically acceptable salts. The compounds are useful as human veterinary and agricultural fungicides.
Patent IE-34804-L (IE)
Title: Therapeutic compositions
IPC: A61K31/43
Filed: 1970-12-11
Abstract: 1,272,660. Therapeutic penicillins. BEECHAM GROUP Ltd. 14 Dec., 1970 [24 Dec., 1969], No. 62828/69. Heading A5B. Antibacterial therapeutic compositions, particularly useful in the treatment of mammary disorders especially bovine mastitis, comprise (A) α-carboxybenzylpenicillin or α-carboxy-3- thienylmethylpenicillin or non-toxic salts thereof and (B) 2, 6-dimethoxyphenylpenicillin, 3-(2, 6-dichlorophenyl) -5- methyl -4- isoxazolylpenicillin or 3-(2-chloro-6-fluorophenyl)-5-methyl-4- isoxazolylpenicillin or non-toxic salts thereof, the components (A) and (B) being present in the weight ratio of 9:1 to 1:9 preferably 1:1. Specified salts include Na, K, Ca, Al, ammonium, triethylamine, procaine, dibenzylamine, N-benzyl-beta-phenethylamine, 1-ephenamine, N, N'-dibenzylethylenediamine, dehydroabietylamine, and N, N'-bis-dehydroabiethylethylenediamine. The compositions may be administered parenterally or intramammarily in the form of sterile solutions or ointments.
[GB1272660A]
Patent IE-45557-L (IE)
Title: Anthracycline glycosides.
IPC: A61P31/04
Filed: 1977-08-15
Abstract: PURPOSE:Anthracyclin glycoside I (R is II or III) and their salt and their nucleic acid complexes, e.g. rhodirubin A and B.
[JP53023961A]