baber/WOPTO huggingface dataset:
Patent NZ-237607-A (NZ)
Title: Vitamin d analogues, pharmaceutical compositions and treatment of animals
Inventor: CALVERLY MARTIN JOHN
IPC: A61K31/59
Filed: 1991-03-27
Abstract: PCT No. PCT/DK91/00091 Sec. 371 Date Jul. 23, 1992 Sec. 102(e) Date Jul. 23, 1992 PCT Filed Mar. 22, 1991 PCT Pub. No. WO91/15475 PCT Pub. Date Oct. 17, 1991.The invention relates to compounds of formula I    <IMAGE>  I  in which formula X is hydrogen or hydroxy; Y is oxygen, sulphur, or oxidized sulfur (S(O) or S(O2)); R1 and R2, which may be the same or different, stand for hydrogen or C1-C6 hydrocarbyl, or R1 and R2, taken together with the carbon atom (starred in formula I) bearing the group X, form a C3-C8 carbocyclic ring; Q is a C1-C8 hydrocarbylene diradical. R3 is hydrogen or C1-C6 hydrocarbyl. R1, R2 and/or Q, may be optionally substituted with one or more deuterium or fluorine atoms; n is 0 or 1. The present compounds show antiinflammatory and immunomodulating effects as well as a strong activity in inducing cell differentiation and inhibiting undesirable proliferation of certain cancer and skin cells.
Patent NZ-238909-A (NZ)
Title: Pyrimidine or triazine derivatives, preparation and medicaments thereof
Inventor: REGNIER GILBERT
IPC: A61P33/00
Filed: 1991-07-10
Abstract: New polymethylene-imines which can be used as medicaments and which correspond to the formula: 
<IMAGE>
 in which:
 X, A, Z, R, R1, R2, R3, R4, Y, Y', m and n are as defined in the description. 
<??>These new derivatives and their physiologically tolerable salts may be used in therapy, in particular for abolishing the resistance of tumour cells to anticancer agents and for abolishing the resistance of parasites to antiparasitic agents.
Patent NZ-241557-A (NZ)
Title: Thrombin inhibitor, pharmaceutical composition and imaging method in a patient
Inventor: MARAGANORE JOHN M
IPC: C07K7/02
Filed: 1992-02-07
Abstract: This invention relates to coating invasive devies with novel biologically active molecules which bind to and inhibit thrombin. These molecules comprise a catalytic site directed moiety (CSDM) of the formula:   <IMAGE>   wherein X is hydrogen or is characterized by a backbone chain consisting of from 1 to 100 atoms; R1 is selected from the group consisting of unsubstituted, mono-substituted, di-substituted and tri-substituted saturated ring structures; R2 is a bond or is characterized by a backbone chain consisting of from 1 to 5 atoms; R3 is a bond or is characterized by a backbone chain consisting of from 1 to 3 atoms; R4 is any amino acid; R5 is any L-amino acid which comprises a guanidinium- or amino-containing side chain group; R6 is a non-amide bond; and Y is characterized by a backbone chain consisting of from 1 to 9 atoms; or the formula:   <IMAGE>   wherein R1' is selected from the group consisting of unsubstituted, mono-substituted, di-substituted and tri-substituted ring structures; R4' is any amino acid comprising a side chain group characterized by the capacity to accept a hydrogen bond at a pH of between about 5.5 and 9.5; and X, R2, R3, R5, R6 and Y are defined as above. Preferred thrombin inhibitors are further characterized by a anion binding exosite associating domain (ABEAM) and a linker portion of between 18  ANGSTROM  and 42  ANGSTROM  in length which connects the Y to the ABEAM.
Patent NZ-266489-A (NZ)
Title: Preparation of unsaturated halogenated alcohols: 5-br-5-cl-4-hydroxy-2-methyl-6,6,6-trifluorohex-2-ene
Inventor: BOWDEN MARTIN CHARLES
IPC: C07C29/64
Filed: 1994-05-25
Abstract: The invention discloses a process for the preparation of a halogenated alcohol of formula: CF3-CXCl-CH(OH)-CH=C(CH3)2 wherein X is bromo or chloro which comprises reacting a compound of formula: CF3CHXCl with 3-methylbut-2-en-1-al in the presence of a strong base and an inert solvent. The products are useful intermediates for the manufacture of insecticides.
Patent NZ-325388-A (NZ)
Title: Skin care composition comprising use of particulate silica for alleviation of acne and related skin disorders
Inventor: SHERIDAN FRANK
IPC: A61K8/00
Filed: 1997-01-08
Abstract: The present invention relates to a method for treating spots and other symptoms of acne and related skins disorders in mammals, which comprises applying to the affected area of the skin of the mammal a non-aqueous composition comprising a dermatologically effective amount of a particulate silica, silica hydrate or precursor thereof. A composition for the alleviation of the symptoms of acne and related skin disorders in a mammal by the topical application of the composition to the affected area of the skin of the mammal, which composition comprises a dermatologically effective amount of an active ingredient in a carrier medium, wherein: a) the active ingredient is anhydrous particulate silica b) the particles of the silica have a primary particle size of less than 10 micrometers c) the anhydrous silica is present in an amount of from 2 to 50% by dry weight of the composition d) the carrier medium for the particulate silica is non-oleaginous, volatile and is selected from one or more alkanols, alkyl glycols, alkyl ketones or alkyl esters in which the alkyl moieties contain 1 to 4 carbon atoms e) the carrier and the composition are non-aqueous
Patent NZ-334032-A (NZ)
Title: Strains of Escherichia coli in fermentation processes for L-threonine production
Inventor: WANG MING-DER
IPC: C12P13/08
Filed: 1997-07-30
Abstract: A process for producing L-threonine, which comprised the steps of: a) Culturing a strain of E.coli strain that is borrelidin resistant in a medium; and b) Recovering L-threonine that is produced by the E.coli; wherein the strain of E.coli:  i) Contains on the chromosome at least one threonine (thr) operon operably linked with at least one non-native promoter that replaces the native threonine promoter via insertion into the chromosome; and ii) Does not require any recombinant plasmids containing one or more genes that encode one or more of the threonine biosynthetic enzymes in order to produce threonine; The non-native promoter is selected from the group consisting of tac, lac, trp, lpp, PL and PR promoters.
Patent NZ-501798-A (NZ)
Title: Electrical lead tag with clippable halves
Inventor: PEARSON ERIC LESTER
IPC: G09F3/02
Filed: 1999-12-16
Abstract: Two halves 15, 16 of an identification tag 14 are clipped together around an electrical lead.  Each half has a recessed surface forming a larger recessed surface 17 when the halves are clipped together.  Indicia such as the testing date can be printed on a medium attached to the recess surface 17 so that the printing is protected from abrasion by the recess.  If the tag is broken apart, the medium will be broken to indicate the disturbance. Addition to 501798
Patent NZ-503117-A (NZ)
Title: Process of preparing paper using a water soluble polymer binder, a water soluble cationic material and a cellulosic thin stock
Inventor: JOHNSTON HOWARD
IPC: D21H17/68
Filed: 1998-09-07
Abstract: A process of preparing paper comprises: a) providing a thin stock suspension of cellulosic fibres; b) mixing into the suspension i) a water soluble anionic or nonionic polymeric binder and ii) a water soluble cationic material selected from water soluble organic coagulants having an intrinsic viscosity below 3dl/g and inorganic coagulants; c) then flocculating the suspension by mixing into the suspension an anionic retention aid; d) draining the flocculated suspension to form a wet sheet and drying the wet sheet.
Patent NZ-503454-A (NZ)
Title: Catalytic antibodies produced from growth factor precursors comprising B cell and T cell surface molecule binding portions
Inventor: KOENTGEN FRANK
IPC: C12N15/19
Filed: 1998-09-18
Abstract: A growth factor precursor comprising a recombinant polypeptide chain or a molecule having modular peptide components or a synthetic equivalent thereof wherein said polypeptide chain or modular peptide molecule comprises at least one B cell surface molecule binding portion, at least one T cell surface molecule binding portion capable of providing T cell dependent help to a B cell, an antigen cleavable by a catalytic antibody and a peptide portion comprising domains from both a variable heavy chain and a variable light chain of an immunoglobulin and wherein said variable heavy chain and variable light chain domains in the growth factor precursor, associate together by intra- and/or inter-domain bonding and substantially prevent the at least one B cell surface molecule binding portion from interacting with a B cell surface molecule such that upon cleavage of said antigen by a catalytic antibody, the peptide comprising said variable heavy chain and variable light chain domain permits the at least one B cell surface molecule binding portion to interact with a B cell surface molecule. Also disclosed is the use of said growth factor precursors to produce catalytic antibodies to specific antigens.
Patent NZ-507399-A (NZ)
Title: Multiple compressor heat pump or air conditioner
Inventor: HEBERT THOMAS H
IPC: F25B13/00
Filed: 1999-04-09
Abstract: In a refrigeration system of the type having a condenser, evaporator, refrigerant and the capabilities of at least heating and cooling modes of operation.  Furthermore a multiple compressor system in parallel operation comprising a primary compressor and at least one secondary compressor is disclosed for maintaining the heat output constant while the outside ambient temperature continues to decrease.    The entire refrigeration system is sized for the primary compressor operating while in the cooling mode.  In the heating mode, the primary compressor operates by itself until the outside ambient temperature falls to a temperature within a particular range.  Once the predetermined temperature set point is met, a secondary compressor begins operating in conjunction with the primary compressor such that the mass flow of refrigerant through the system in the heating mode of operation is no greater than that of the primary compressor operating alone in the cooling mode.  While the outside temperature continues to decrease, additional secondary compressors may be included to maintain a constant heat output.  In the cooling mode, only a single compressor is required to operate the system. Each of the compressors may alternate with any other so that the lives of the compressors are preserved.
Patent NZ-510342-A (NZ)
Title: Reduced calorie plastic fat composition
Inventor: CHANG PING WU
IPC: A23L33/20
Filed: 1999-09-10
Abstract: Described is a reduced-calorie, edible plastic fat composition comprising a triglyceride mixture of two or more triglycerides selected from the formulae SSL, SLS, LLS and LSL, where: Each R is independently a long chain fatty acid residue having between 16 and 22 carbon atoms. Each R1 is independently a short chain acid residue selected from acetyl, propionyl and butyryl. The mixture contains between 40 wt % to 95 wt % di-short species of the Formula SSL and the Formula SLS, and from 5 wt % to 60 wt % di-long species of the Formula LLS and the Formula LSL, with wt % being based on the total weight of the di-short and di-long species. From 3 wt % to 40 wt % of the R groups are unsaturated, the unsaturation being substantially monounsaturation, with wt % being based on the total weight of R groups in the mixture. The triglyceride mixture is plastic at ambient temperature. The composition contains no more that 20 wt % of a triglyceride plasticizing additive, with wt % being based on the total weight of the composition.  The edible fat composition may be used to replace edible fat in shortening and in margarine compositions.
Patent NZ-512884-A (NZ)
Title: Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands
Inventor: BUNNELLE WILLIAM H
IPC: C07D401/08
Filed: 2000-01-25
Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt thereof wherein: V is selected from the group consisting of a covalent bond and CH2; W is selected from the group consisting of a covalent bond, CH2 and CH2CH2; X is selected from the group consisting of a covalent bond and CH2; Y is selected from the group consisting of a covalent bond, CH2, and CH2CH2; Z is selected from the group consisting of CH2, CH2CH2, and CH2CH2CH2; L1 is selected from the group consisting of a covalent bond and (CH2)n; n is 1-5; R1 is selected from the group consisting of (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), and (l); R2 is selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl, aminoalkyl, aminocarbonylalkyl, benzyloxycarbonyl, cyanoalkyl, dihydro-3-pyridinylcarbonyl, hydroxy, hydroxyalkyl, phenoxycarbonyl, and -NH2; are useful for controlling synaptic transmission in mammal.
Patent NZ-515537-A (NZ)
Title: Vang base with fixed tang and pivoting cleat arm
Inventor: HARTLMEIER GREG
IPC: B63H9/10
Filed: 2001-11-16
Abstract: A boom vang base for a sailing craft permits the lead line through the cam cleat to be aligned with the sailor irrespective of the boom angle.  For rotating masts 54 the cam cleat 60 is mounted on an arm 56 that is pivoted at 61 to the vang fitting 52 attached to the mast.  For fixed masts 54', the vang base 52' is pivotally attached to the mast at 300 so that the lower block 58' can follow the boom angle to prevent tangling of the lines 66', and the cam cleat is in turn pivotally mounted on the vang base at 61' to allow ready cleating from any direction of the lead line 68'.
Patent NZ-517159-A (NZ)
Title: Peroxovanadium compounds useful as protein tyrosine phosphatase (PTP) inhibitors
Inventor: FAURE ROBERT
IPC: A61K33/24
Filed: 2000-08-03
Abstract: A pharmaceutical composition contains a peroxometallic derivative of formula (I) wherein: Y is oxygen or hydroxyl; Z and Z' are independently oxygen or a peroxide with at least one of Z and Z' being peroxide and L and L' are a group that can donate one electron pair. The compositions are useful in preventing the progression of a pathology complicated by angiogenesis such as arthritis, psoriasis or solid tumour growth or for preventing or lessening endothelin production or preventing restenosis following angioplasty.
Patent NZ-518218-A (NZ)
Title: Ligand activated transcriptional regulator proteins
Inventor: BARBAS CARLOS F
IPC: A61K48/00
Filed: 2000-10-23
Abstract: Fusion proteins for use as ligand-dependent transcriptional are provided. The fusion proteins include a nucleotide binding domain operatively linked to a ligand-binding domain. They also can include a transcription regulating domain. The nucleotide binding domain is a zinc-finger peptide that binds to a targeted contiguous nucleotide sequence of from 3 to 18 nucleotides are provided. The fusion proteins are used for gene therapy. Also provided are polynucleotides encoding the fusion proteins, expression vectors, and transfected cells.
Patent NZ-519848-A (NZ)
Title: Mounting a module including appliances such as flat screen television in an under cabinet fashion
Inventor: HARRISON ROBERT G
IPC: H04N21/462
Filed: 2000-04-04
Abstract: Appliances (20) designed to be mounted on the bottom (54, 56) of a structure such as an overhead cabinet system (37). The appliance has an integrated unit (22) (or module) which includes a television tuner (140) and, optionally, a player (142) for an optically readable disk (144). The appliance (20) also has a display unit (24) of the flat screen type. The display unit (24) is attached to the appliance module (22) by a universal pivot mechanism (248) which allows the unit (24) to be: (a) rotated and tilted to face a viewer, and (b) folded up against the appliance module (22) and out of the way when the display (24) unit is not in use.
Patent NZ-522051-A (NZ)
Title: Pharmaceutical gel composition
Inventor: SMITH ROBERT ALAN
IPC: A61P17/02
Filed: 2001-03-26
Abstract: Topical composition for treatment of wounds, including a glycol, a cellulose derivative and an aluminium compound. Also disclosed is the use of such a composition for the manufacture of a medicament for topical treatment of wounds.
Patent NZ-523328-A (NZ)
Title: Method and apparatus for providing computer services
Inventor: TREMAIN GEOFFREY DONALD
IPC: G06F21/55
Filed: 2001-07-03
Abstract: An apparatus and method are disclosed for providing one or more computer services to a plurality of customers (A, B, C). At least one virtual machine (VS) is set up on a real computer (30) for each of the customers (A, B, C) at the request of each of the customers (A, B, C). Each virtual machine (VS) for each of the customers (A, B, C) has a specification specified by the respective customer (A, B, C).
Patent NZ-527076-A (NZ)
Title: Graft rejection inhibitors used in combination with immunosuppressants
Inventor: SUZUKI SEIICHI
IPC: C07K16/28
Filed: 2002-02-05
Abstract: A substance selected from an antibody that binds AILIM, a polypeptide comprising the whole or a portion of an extracellular region of AILIM, a fusion polypeptide comprising the whole or a portion of an extracellular region of AILIM and the constant region of an immunoglobin heavy chain and polypeptide that binds to AILIM, can be used for the manufacture of a medicament that is formulated for use in combination with one or more immunosuppressive agents for suppressing, treating or preventing graft rejection accompanying the transplantation of an organ or tissue.
Patent NZ-528698-A (NZ)
Title: Novel PRO618 polypeptides and nucleic acids encoding same with similarity to enteropeptidase
Inventor: GURNEY AUSTIN L
IPC: C07K16/40
Filed: 1999-03-08
Abstract: An isolated nucleic acid having at least 80% sequence identity to a nucleotide sequence that encodes a polypeptide designated PRO618 comprising the amino acid sequence SEQ ID NO:169. Preferably the nucleic acid comprises the sequence of SEQ ID NO:168 or is that deposited under accession number ATCC 209813. Vectors, isolated host cells, processes for preparing the polypeptide and antibodies are also described. (62) Divided out of 507435
Patent NZ-529094-A (NZ)
Title: Methods for the identification of antiviral compounds
Inventor: BRUS RONALD HENDRIK PETER
IPC: G01N33/50
Filed: 2002-05-06
Abstract: Disclosed are methods for determining whether a compound influences a phase in the life cycle of a virus comprising providing a cell with said compound and with at least a fragment of said virus sufficient for performing said phase and determining whether said phase is influenced in said cell, said cell comprising a nucleic acid encoding an adenovirus early protein or a functional part, derivative and/or analogue of said adenovirus early protein, and wherein the cell is derived from a kidney, a retina or amniotic fluid. In another aspect the disclosure provides the use of a cell, said cell comprising nucleic acid encoding an adenovirus early protein, for screening a library of compounds for the presence of a compound capable of influencing a phase in the life cycle of a virus capable of entering said cell. In yet another aspect, the disclosure provides methods for identifying a compound with antiviral activity comprising providing a cell with at least a fragment of a virus, said fragment capable of performing a step in the life cycle of said virus, providing said cell with a compound and determining whether said compound is capable of influencing said step in the life cycle of said virus, wherein said cell comprises a nucleic acid encoding an adenovirus early protein or a functional part, derivative and/or analogue of said adenovirus early protein.
Patent NZ-529172-A (NZ)
Title: Improvements in leather processing
Inventor: COVINGTON TONY
IPC: C14C3/02
Filed: 2002-04-26
Abstract: A process for improving softness and/or area yield of leather which comprises providing animal skins tanned with chromium (Ill) salts or an aldehydic tanning agent, and treating the tanned skins with an enzyme mixture comprising a protease and an elastase.
Patent NZ-532651-A (NZ)
Title: Wire holders
Inventor: BOYLE PETER HAMILTON
IPC: E04H17/10
Filed: 2002-10-01
Abstract: A wire holder (10) to attach fencing wire (22) to metal posts known as star pickets (23) which comprise three equi-spaced flanges (24) at least one of which being provided with a plurality of spaced apertures (25). The holder includes a capturing part (12) and an attaching part in the form of a loop (19) which may be separate or integral. The capturing part is located about the picket to capture the wire and terminates in first and second ends (13, 14), adapted to be located on opposite sides of the flange adjacent the aperture; and the attaching part cooperates with the capturing part to secure the holder to the picket. The first and second ends can be of various configurations, including two looped portions through which a U-shaped attaching part (19) may pass through, or a single loop at one end with a pin-like member at the other end.
Patent NZ-533488-A (NZ)
Title: Weathervaning LNG offloading system
Inventor: WILLE HEIN
IPC: B63B27/24
Filed: 2002-12-12
Abstract: A cryogenic fluid offloading system, having a tanker vessel (2) moored in line with an offshore mooring construction (4, 8) and connected to a processing unit, such as regasification plant (13). The regasification plant has no large storage facilities, the tanker being unloaded in dependence on onshore demand for gas.
Patent NZ-535169-A (NZ)
Title: Process for making chiral 1,4-disubstituted piperazines
Inventor: FEIGELSON GREGG BRIAN
IPC: C07D319/18
Filed: 2003-03-10
Abstract: Disclosed is a process for a stereoselective preparation of novel chiral nitrogen mustard derivatives useful in synthesizing optically active 1,4-disubstituted piperazines of formula (I) wherein R, Ar, and Q are defined as set forth herein, and intermediate compounds therefor. The 1,4-disubstituted piperazines act as SHT1A receptor binding agents useful in the treatment of Central Nervous System (CNS) disorders.
Patent NZ-537821-A (NZ)
Title: Anti-viral compositions useful for treating one or more adverse effects of viral infections
Inventor: ROSENBLOOM RICHARD A
IPC: A61P29/00
Filed: 2003-07-24
Abstract: Disclosed is an anti-viral composition which includes a first ingredient obtained from ginger, a second ingredient obtained from green tea, a third ingredient available from turmeric, and an acceptable carrier. The first and second ingredients are present in an amount which when combined is effective to reduce, treat or prevent an adverse effect of a viral infection when administered to a patient prior to expected exposure to a virus, concurrently with exposure to a virus or after exposure to a virus.
Patent NZ-538009-A (NZ)
Title: Updating presence information
Inventor: HONKALA ANU
IPC: H04W80/10
Filed: 2003-07-03
Abstract: In a communication network, which includes at least one user (50) associated with a plurality of terminals (2a, 2b, 2c), a method of administering presence information is disclosed. The presence information is associated with a user (50) and the plurality of terminals (2a, 2b, 2c), where the method includes the step of (a) transmitting a first message from one of the terminals (2a, 2b, 2c) to a server (1), where the first message includes presence information and an identifier of the first terminal (2a, 2b, 2c), and (b) transmitting a second message, which includes at least a part of the presence information from the server (1).
Patent NZ-544434-A (NZ)
Title: Retaining wall and blocks for the formation thereof
Inventor: ALLINGTON CHRIS JAMES
Filed: 2006-03-31
Abstract: A block having at least one front face, at least one back face, sides connecting the front and back faces, a top surface, a bottom surface and at least one cavity passing through the entire height of the block from the top surface to the bottom surface. The cavity is positioned so that the centre of mass of the block lies closer to the back face than does the geometric centre of the block. The block is tapered from the front to the back such that the back face is narrower than the front of the block.