baber/WOPTO huggingface dataset:
Patent NZ-230550-A (NZ)
Title: Cycloalkyl-substituted glutaramide derivatives and pharmaceutical compositions
Inventor: DANILEWICZ JOHN CHRISTOPHER
IPC: C07C235/82
Filed: 1989-09-04
Abstract: Compounds of the formula: <CHEM> Wherein A completes a 5 or 6 membered carbocyclic ring which may be saturated or monounsaturated; R<1> is H or (C1-C4)alkyl; R and R<4> are H, (C1-C6)alkyl, C3-C7 cycloalkyl, benzyl, or an alternative biolabile ester-forming group; Y is either a direct bond or an alkylene group of from 1 to 6 carbon atoms; R<2> is H, aryl, heterocyclyl, R<6>CONR<5>-, R<7>NR<5>CO-, R<7>NR<5>SO2- or R<8>SO2NR<5>-, with the proviso that Y is not a direct bond when R<2> is H, aryl or heterocyclyl; wherein R<5> is H, (C1-C6)alkyl or aryl(C1-C6)alkyl; R<6> is (C1-C6)alkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl, heterocyclyl(C1-C6)alkyl or a group of the formula R<9>R<1><0>R<1><1>C- wherein R<9> is H, OH, (C1-C6)alkoxy, (C1-C6)alkyl, hydroxy(C1-C6)alkyl, aryl(C1-C6)alkyl, (C2-C6)alkenyl, heterocyclyl, heterocyclyl(C1-C6)alkyl, R<1><2>CONH-, R<1><2>SO2NH- or (R<1><3>)2N-; R<1><0> and R<1><1> are H or (C1-C6)alkyl; or R<1><0> is H and R<1><1> is amino(C1-C6)alkyl, imidazolylmethyl, aryl, aryl(C1-C6)alkyl, aryl(C1-C6)alkoxy(C1-C6)alkoxy, hydroxy(C1-C6)alkyl or methylthio(C1-C6)alkyl; or the two groups R<1><0> and R<1><1> form a 3 to 6 membered carbocyclic ring or a pyrrolidine or piperidine ring which may optionally be substituted by amino, (C2-C4)alkanoyl or aroyl; R<1><2> is (C1-C6)alkyl, (C3-C7)cycloalkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl or heterocyclyl(C1-C6)alkyl; each R<1><3> is H, (C1-C6)alkyl, aryl(C1-C6)alkyl or the two groups R<1><3> form a pyrrolidinyl, piperidino, morpholino, piperazinyl or N-(C1-C4)alkyl-piperazinyl group; R<7> is (C1-C6)alkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl, heterocyclyl(C1-C6)alkyl or a group of the formula R<1><0>R<1><1>R<1><4>C- wherein R<1><0> and R<1><1> are as previously defined and R<1><4> is (R<1><3>)2NCO-, R<1><2>OCH2- or R<1><5>OCO, wherein R<1><2> and R<1><3> are as previously defined and R<1><5> is (C1-C6)alkyl, (C3-C7)cycloalkyl or aryl(C1-C6)alkyl; and R<8> is (C1-C6)alkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl or heterocyclyl(C1-C6)alkyl;  R<3> is a group of the formula: <CHEM> wherein R<1><6> is H, halo, 4-OH, 4-(C1-C6 alkoxy), 4-(C3-C7 cycloalkoxy) 4-(C2-C6 alkenyloxy), 4-[(C1-C6 alkoxy)carbonyloxy], 4-[(C3-C7 cycloalkoxy)carbonyloxy], or 3-(C1-C4 alkyl)SO2NH-; and R<2><0> is H, C1-C4 alkyl, C1-C4 alkoxy, C2-C6 alkanoyl or halo; or R<3> is a group of the formula: <CHEM> wherein said groups may optionally be substituted in the fused benzene ring by C1-C4 alkyl, C1-C4 alkoxy, OH, halo or CF3; are antihypertensive agents of utility in the treatment of hypertension, heart failure and renal insufficiency.
Patent NZ-233413-A (NZ)
Title: Composition comprising a conjugate of an antibody directed against a tumour associated antigen and a biological response modifier
Inventor: ROSENBLUM MICHAEL G
IPC: A61P27/02
Filed: 1990-04-23
Abstract: The present invention provides a novel conjugate of an antibody with a biological response modifiers; delivery system which delivers biological response modifiers to target tissues and cells. The present invention also provides a method for treating diseases by administering antibody-biological response modifier conjugates. For example, a monoclonal antibody conjugated to a lymphokine or cytokine, such as for example, TNF.
Patent NZ-233469-A (NZ)
Inventor: SACCOMANO NICHOLAS ALEX
IPC: A01N63/02
Filed: 1990-04-27
Abstract: This invention relates to certain polypeptides found to be present in the venom of the Agelenopsis aperta spider. The polypeptides block calcium channels in cells of various organisms and are useful in blocking said calcium channels in cells, per se, in the treatment of calcium channel mediated diseases and conditions and in the control of invertebrate pests.
Patent NZ-241427-A (NZ)
Title: Benzamide derivatives, and pharmaceutical compositions thereof
Inventor: ASHTON MICHAEL JOHN
IPC: C07C235/38
Filed: 1992-01-28
Abstract: Benzamide derivatives of the formula (I): <CHEM> wherein R<1> represents alkyl, R<2> represents alkyl or mono-, bi- or tricycloalkyl, R<3> represents an optionally substituted phenyl, naphthyl or heterocyclyl group, and Z represents oxygen or sulphur, and when said heterocyclyl groups contain one or more nitrogen ring atoms, N-oxides thereof, and pharmaceutically acceptable salts thereof, possess useful pharmacological properties.
Patent NZ-243667-A (NZ)
Title: Chewing gum containing coated curculin derivative or fruit containing curculin
Inventor: YOSHIE KURIHARA
IPC: A23L27/30
Filed: 1992-07-22
Abstract: The chewing gum of the present invention contains a coated material prepared by coating Curculigo latifolia fruits, processed Curculigo latifolia fruits or a component containing curculin obtained therefrom with a coating agent.
Patent NZ-245628-A (NZ)
Title: Cosmetic or dermatological compositions comprising a fatty acid diester of 2,3-butanediol as viscosity agent and emollient
Inventor: TRAITLER HELMUT
IPC: A61K8/00
Filed: 1993-01-06
Abstract: The diesters of 2,3-butanediol and of C16 - C22 fatty acid as emollient and viscosity agents lend themselves to the manufacture of cosmetic compositions in the form of emulsions or anhydrous compositions which have excellent physicochemical and feel properties.
Patent NZ-260445-A (NZ)
Title: 2-(substituted benzoyl) benzofuran (and benzothiophene) derivatives and medicaments
Inventor: FISCHER RUDIGER
IPC: C07D413/06
Filed: 1994-05-03
Abstract: The benzofuranyl- and -thiophenyl-alkane-carboxylic acid derivatives of the formula (I) <CHEM> wherein R1, R2, R3, T, V, and W are as defined in Claim 1 are prepared by cyclisation of hydroxy acetophenones and related compounds or by Wittig-reaction of benzofuranyl aldehydes. The compounds can be used to prepare medicaments showing antiinflammatory activity.
Patent NZ-264151-A (NZ)
Title: Quinoline derivatives
Inventor: STOLTEFUSS JURGEN
IPC: C07D215/14
Filed: 1992-05-28
Abstract: The present invention relates to new 2-amino-5-cyano-4-quinoline-1,4-dihydropyridines, processes for their preparation and their use in medicaments, in particular in agents for the treatment of cardiovascular diseases.
Patent NZ-268693-A (NZ)
Title: Magnesium omeprazole having a degree of crystallinity greater than 70%
Inventor: KALLSTROM LARS AKE
IPC: C07F3/02
Filed: 1994-07-08
Abstract: A novel compound form of magnesium omeprazole, i.e. with a degree of crystallinity which is higher than 70% as determined by x-ray powder diffraction, useful in the manufacture of pharmaceutical formulations, the use of the product and the process for its production are described.
Patent NZ-282823-A (NZ)
Title: Agent, for preserving slaughtered animal carcasses, comprising an aqueous solution of a stock composition and an activator selected from acetic and lactic acids
Inventor: STEMMLER HEINZ
IPC: A23L35/00
Filed: 1995-03-30
Abstract: PCT No. PCT/EP95/01180 Sec. 371 Date Oct. 16, 1997 Sec. 102(e) Date Oct. 16, 1997 PCT Filed Mar. 30, 1995 PCT Pub. No. WO95/33383 PCT Pub. Date Dec. 14, 1995The invention concerns an agent for enhancing the keeping quality of bodies of slaughtered animals, parts of bodies of slaughtered animals, and hamburger patties, a process for the use thereof, and bodies of slaughtered animals, parts of bodies of slaughtered animals, and hamburger patties which are preserved according to the process.
Patent NZ-320009-A (NZ)
Title: Modified non-intercalated kaolins
Inventor: SINGH BALBIR
IPC: B01J20/18
Filed: 1996-10-23
Abstract: PCT No. PCT/AU96/00667 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15427 PCT Pub. Date May 1, 1997A process for the preparation of a modified kaolin from a kaolin group mineral which includes expansion and contraction of layers of the kaolin group mineral. The layers comprising one Si-tetrahedral sheet and one Al-octahedral sheet. The expansion and contraction may be initiated by initial intercalation of a reagent which can penetrate kaolin layers to reach an interlayer region therebetween to form an intercalate. Subsequently, the intercalation nay be followed by de-intercalation which involves the removal of the reagent. By the above process, there is provided crystalline modified kaolins having the following properties: (i) an increased interlayer space compared to corresponding kaolin group minerals; (ii) an increased susceptibility to intercalation by cations, anions or salts compared to corresponding kaolin group minerals; and (iii) an increased exfoliated morphology compared to corresponding kaolin group minerals.
Patent NZ-329772-A (NZ)
Title: Method and device for supplying a multicomponent fluid thermosetting resin gluing system, a second stream is brought to encircle a first stream
Inventor: VESTERLUND LENNART
IPC: B05B1/14
Filed: 1998-02-17
Abstract: A method for supplying a multicomponent fluid thermosetting resin gluing system in which a first fluid component is brought to flow in a first stream, and a second fluid component is brought to flow in a second stream, wherein the second stream is brought to encircle the first stream. A device for carrying out said method comprising a first body (10) provided with outlet conduits (20,21,22); a second body (30) having as many outlet apertures (40,41,42) as there are outlet conduits of the first body; each conduit being introduced into one aperture. Use of said device for which the apertures in the second body shell are fitted with externally protruding outlet conduits having an outlet nozzle, each conduit introduced into the same aperture extending beyond the nozzle of the conduit fitted to the same aperture, for supplying a multicomponent fluid thermosetting resin gluing system according to said method.
Patent NZ-333180-A (NZ)
Title: Topical aqueous gel composition containing a combination of a non-steroidal anti-inflammatory drug, a xanthine derivative, a gelling agent, water and a cosolvent
Inventor: LEEVES NIGEL JOHN
IPC: A61K31/403
Filed: 1997-06-24
Abstract: The topical gel comprises: a) 0.1 to 20% by weight of an non-steroidal anti-inflammatory drug; b) 0.1-10% by weight of a xanthine derivative; c) 0.1-10% by weight of gelling agents; d) 5-60% by weight of co-solvent for the NSAID and the xanthine derivative and e) 10-90% by weight of water. The NSAID is selected from propionic acid derivative, acetic acid derivative, fenamic acid derivative, biphenylcarboxylic acid derivative and an oxicam or salts thereof and mixtures thereof. The xanthine derivative has the formula I wherein: R1-R3 are independently H, methyl or ethyl with at least two of R1-R3 being methyl or ethyl or mixtures thereof. The gelling agents can be carboxy containing mono-ethyleneically unsaturated monomer such as a crosslinked carboxyl vinyl polymer of acetic acid. The co-solvent is an alcohol such as ethanol.
Patent NZ-334025-A (NZ)
Title: Therapeutic methods and compositions involving isoflavones
Inventor: KELLY GRAHAM EDMUND
IPC: A61P19/02
Filed: 1997-08-29
Abstract: Therapeutic methods of treatment, compositions and foodstuffs are described which contain isoflavone compounds described by groups A and B, in which: Z is H, R1 is H, or RACO, where RA is C1-10alkyl or an amino acid, R2 is H, OH, or ORB, where RB is an amino acid, or CORA where RA is as previously defined, W is H, A is H or OH, and B is selected from (a), (b), (c), or W is H, and A and B taken together form a six-membered ring selected from (d), or W, A and B taken with the groups with which they are associated comprise (e), or W and A taken together with the groups with which they are associated comprise (f) and B is (g), R3 is H, CORA where RA is as previously defined, CO2RC where RC is C1-10alkyl, or CORB where RB is as previously defined, R4 is H, CORD where RD is H, OH, C1-10alkyl or an amino acid, CO2RC where RC is as previously defined, CORE where RE is H, C1-10alkyl or an amino acid, COOH, CORC where RC is as previously defined, or CONHRE where RE is as previously defined, R5 is H, CO2RC where RC is as previously defined, or CORCORE where RC and RE are as previously defined, and where the two R5 groups are attached to the same group they are the same or different, R6 is H or hydroxy C1-10alkyl, X is preferably O, but may be N or S, and Y is (h),  R7 is H, or C1-10alkyl,  R11 is H or OH  R12 is H, COOH, CO2RC where RC is as previously defined, or CONHRE where RE is as previously defined.  Application of formula 1 have particular utility and effectiveness in the treatment, prophylaxis, amelioration defence against, and/or prevention of menopausal syndrome including hot flushes, anxiety, and depression, mood swings, night sweats, headaches, and urinary incontinence; osteoporosis; premenstrual syndrome, including fluid retention, cyclical mastalgia, and dysmenorrhoea; Reynaud's Syndrome; Reynaud's Phenomenon; Buergers Disease; coronary artery spasm; migraine headaches; hypertension; benign prostatic hypertrophy; breast cancer; uterine cancer; ovarian cancer; testicular cancer; large bowel cancer; endometrial cancer; prostatic cancer; uterine cancer; atherosclerosis; Alzheimers disease; inflammatory diseases including inflammatory bowel disease, ulcerative colitis, Crohns disease; rheumatic diseases including rheumatoid arthritis; acne; baldness including male pattern baldness (alopecia hereditaria); psoriasis and diseases associated with oxidant stress including cancer, myocardial infarction stroke, arthritis, sunlight induced skin damage or cataracts.
Patent NZ-335781-A (NZ)
Title: Production of vehicle frames from modular structural components
Inventor: TRIVEDI MUKESH R
IPC: B62D21/02
Filed: 1999-05-14
Abstract: Automotive frame members are constructed using modular components 12, 14.  Primary components 12 consist of a web portion  and flange portions 18 at each end of the web.  Secondary connectors 14 are U-shaped.  Frame members are constructed by joining two primary components 12 using connectors 14.   The primary and secondary components 12, 14 are selected from a "family" of such components so that the resultant frame member has a required set of structural properties.
Patent NZ-501461-A (NZ)
Title: Optical fibre cable core with strength members partially embedded in and gripped by buffer tube wall
Inventor: WELLS BEN H
IPC: G02B6/44
Filed: 1999-12-02
Abstract: The core of an optical fiber cable includes a buffer tube 40 having an outer periphery 45 and housing optical fibers 14.  At least two radially incompressible strength members 22 are partially embedded in the wall of the buffer tube, extend longitudinally along the core and are spaced circumferentially around the buffer tube.  The strength members are not as thick as the wall, and are at least flush with the periphery of the buffer tube if not proud thereof.  By extruding at least that portion of the buffer tube around the strength members, as a consequence of the cooling of the extrusion, the buffer tube material 12b surrounding the strength members engages the strength members and applies coupling forces to the strength members directed radially inwardly of the strength members.
Patent NZ-501634-A (NZ)
Title: Compositions comprising a UVA blocker a UVB blocker and a MMP inhibitor and methods for inhibiting photoaging of skin and degradation of collagen
Inventor: VOORHEES JOHN J
IPC: C03C4/08
Filed: 1998-06-03
Abstract: A method for inhibiting degradation of collagen by UV photoaging of human skin, comprising the daily application of a combination of a UVA blocker, a UVB blocker and an MMP inhibitor to the skin at least 8 hours prior to exposure of the skin to UV radiation. The MMP inhibitor may be selected from NAC, FDO and vitamin C.
Patent NZ-503623-A (NZ)
Title: Obturator comprises a rigid part and a flexible portion at the machine end
Inventor: NEAME SIMON
IPC: A61M16/04
Filed: 2000-03-27
Abstract: The specification describes an obdurator for a curved medical tube. One end of the obdurator has a tapered nose which is able to be received by a patient.  The machine end is able to be released from the tube by twisting.  The obdurator is rigid along a major part of its length, but is flexible enough to permit twisting at the machine end.
Patent NZ-506654-A (NZ)
Title: Method and device for centrifugal skimming of whey
Inventor: ZETTIER KARL-HEINZ
IPC: A23C7/04
Filed: 1999-03-25
Abstract: A method for the skimming of whey, resulting in better whey cream fat quality and allowing for automatic regulation of the concentration of cream.  The raw whey is fed into a skimming separator (6) and broken down into a skimmed whey phase and whey cream phase. The whey cream is discharged through a discharge line (8) and a part thereof corresponding to 0.5-2.0 % of the volumetric flow of the raw whey that is fed into the skimming separator (6) is returned to the feed line (3) of the skimming separator by means of a recirculating device (9).  A densimeter can be arranged in the recirculating device so that density measurements can be carried out. The density values are transmitted to an evaluation device enabling regulation of a control valve (13), which is placed in the discharge line (8) for the whey cream.  The method and device for implementing said method are used in the processing of whey which is produced during the production of cheese after the cheese has been separated from the fat during the coagulation of the milk.
Patent NZ-514109-A (NZ)
Title: Delivery system for dispensing volatiles
Inventor: HELF THOMAS A
IPC: B05B17/00
Filed: 2000-02-09
Abstract: Disclosed is a piezoelectric liquid delivery system  or atomizer  for production of droplets of  liquid  or  liquid suspensions  by  means of  a  battery  operated  continuous action   dispenser  utilizing an  orifice  plate   (3)   in communication  with a piezoelectric element  (2).  There  is also  use of a wick (7) having specified properties and high compliance.
Patent NZ-516894-A (NZ)
Title: Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
Inventor: ASTATKE MEKBIB
IPC: C12Q1/68
Filed: 2000-06-30
Abstract: A compound for inhibiting nucleic acid synthesis, comprising a nucleic acid inhibitor that is capable of binding to or has affinity for an enzyme with polymerase activity, wherein said inhibitor comprises a 5' portion and a 3' portion, said 3' portion comprising one or more deoxyribonucleotides or derivatives thereof and said 5' portion comprising one or more ribonucleotides or derivatives thereof. Also claimed is a method for amplifying a nucleic acid molecule comprising mixing said nucleic acid synthesis inhibitor with one or more enzymes with polymerase activity and one or more templates, and incubating said mixture under sufficient conditions to amplify one or more nucleic acid molecules complementary to all or a portion of said templates.
Patent NZ-518311-A (NZ)
Title: Magnetic targeted carrier composed of iron and ceramic porous materials for the targeted delivery of biologically active agents
Inventor: RUDGE SCOTT RAYMOND
IPC: A61K47/48
Filed: 2000-10-13
Abstract: A magnetically responsive composition comprises composite particles including metallic iron and ceramic or a derivative thereof. The ratio of ceramic:iron is in the range from 1 % to 95% ceramic to 5% to 99% iron, and the diameter of each particle is 0.1 to 10.0 um.
Patent NZ-519810-A (NZ)
Title: Osmotic beneficial agent delivery system
Inventor: FERREIRA PAMELA
IPC: A61K9/22
Filed: 2000-12-13
Abstract: An osmotic beneficial agent delivery system includes an implantable osmotic delivery device and a catheter for delivery of the beneficial agent from the delivery device to a delivery location. The beneficial agent delivery system includes a catheter and a docking station which are implanted in the patient with a distal end of the catheter positioned at a delivery site. The catheter and docking station are left in place while an implant containing the beneficial agent is removably connected to the catheter at the docking station and can be replaced as needed. The docking station provides a connection between a catheter and the implant allowing the implant to be replaced periodically while the catheter and the docking station remain in place.
Patent NZ-520257-A (NZ)
Title: Multiphoton excitation through optical fibers for fluorescence spectroscopy
Inventor: WEBB WATT W
IPC: A61B1/07
Filed: 2001-02-07
Abstract: Abstract of WO0159423 Disclosed is a method of applying radiation through an optical fiber for detecting disease within a plant or animal or imaging a particular tissue of a plant or animal. In addition, fluorescence can be detected and localized within a subject by such application of radiation through an optical fiber. The radiation is effective to promote simultaneous multiphoton excitation. The optical fibers are used alone to examine internal regions of tissue, in conjunction with an optical biopsy needle to evaluate sub-surface tissue, or with an endoscope to evaluate tissue within body cavities.
Patent NZ-521011-A (NZ)
Title: Electromechanical key and lock with provisions to selectively allow authorised users based on the public identification data
Inventor: LIDEN INGE
IPC: G07C9/00
Filed: 2001-03-09
Abstract: A key and lock device comprises a key and a stand-alone lock. The key has an electronic circuitry with a first memory and a first contact. The lock has an electronic circuitry with a second memory means, and a second contact means arranged to co-operate with the first contact means. Also, there is a blocking mechanism adapted to block operation of the lock unless an authorised key is inserted in the lock. The memory of the key stores a public identification item of the key identifying a group of keys having identical mechanical codes. In the memory of the lock, there is provided a list of the public and secret identification items of authorised keys and a list of the public identification item of non-authorised keys, A key is authorised if the public and secret identification items are present in the list of authorised keys and the public identification item thereof is absent in the list of non-authorised keys. This provides for an easy and flexible way of authorising key and lock devices and adding new keys to a system.