baber/WOPTO huggingface dataset:
Patent CA-2088917-A1 (CA)
Title: Therapeutic ribozyme compositions
Inventor: ALTMAN SIDNEY
IPC: C12N15/54
Filed: 1991-08-15
Abstract: It is possible to target any RNA molecule for cleavage by RNase P by forming a hybrid region consisting of a short se-quence of base pairs followed ay a terminal 3'-NCCA sequence. In the preferred embodiment, the region is formed by addition of an external guide sequence consisting of a nucleotide sequence complementary to the targeted site which includes a 3'-NNCA, wherein the sequence hybridizes to the targeted RNA to form a short sequence of double-stranded RNA under conditions pro-moting cleavage of the substrate at the nucleotide at the 5' side of the base-paired region by the RNase P. Specificity is deter-mined by the complementary sequence. The sequence is preferably ten to fifteen nucleotides in length and may contain non-com-plementary nucleotides. These embodiments are particularly useful in the treatment of viral diseases and disorders associated with expression of specific proteins from mRNA.
Patent CA-2090038-A1 (CA)
Title: Ligand stabilized +1 metal beta-diketonate coordination complexes and their use in chemical vapor deposition of metal films
Inventor: BAUM THOMAS H
IPC: C07F15/00
Filed: 1991-01-23
Abstract: Chemical vapor deposition precursors for depositing copper, silver, rhodium and iridium metals on substrates comprise ligand stabilized +1 metal beta-diketonate coordination complexes of said metals. Uses of such precursors in CVD processes are also provided.
Patent CA-2091846-A1 (CA)
Title: Analog timepiece movement for large diameter energy cell
Inventor: SCHWARTZ HERBERT
IPC: G04C3/00
Filed: 1993-03-17
Abstract: PI-1325 - Schwartz ABSTRACT OF THE DISCLOSURE        Analog timepiece movement adapted for a large diameter, thin energy cell, the movement comprising a molded frame of insulating material having a top central wall, and having depending peripheral side wall portions.  A flat bridge of insulating material divides the movement into an inner cavity.  A stepping motor and gear train are disposed in the inner cavity and a quartz crystal is disposed outside of the cavity.  One of the wheel assemblies is of non-magnetic material and extends through a hole in by the stepping motor stator.  The peripheral wall portions and the bridge together define a circular envelope in the outer cavity adapted to locate and contain said energy cell.  The movement is substantially elliptical in shape, the ellipse having a minor axis slightly greater than that of the energy cell, and the quartz crystal is disposed on one end of the elliptical frame alongside the energy cell.
Patent CA-2091897-A1 (CA)
Title: Isoxazole compound, pharmaceutically acceptable salt thereof, and medicinal use thereof
Inventor: SUZUKI MASAHIRO
IPC: A61P43/00
Filed: 1991-09-20
Abstract: ABSTRACT OF THE DISCLOSURE      Isoxazole compound represented by general formula (1), pharmaceutically acceptable salt thereof, and medicinal use thereof; wherein R represents hydrogen or lower alkoxy, and R1 represents a group represented by general formula (2) wherein A represents NH or O, B represents CH2 or CO, m represents 0 or 1, n represents an integer of 1 to 12, X reprssents H, OH or lower alkoxycarbonyl, and Y represents H or Ph which may be haloyenated: a group repre ented by general formula (3) wherein Z represents pyrimidinyl: or a group represented by general formula (4) wherein R2 represents styryl which may be hydroxylated.
Patent CA-2095211-A1 (CA)
Title: Pneumatic tires having reduced rolling resistance
Inventor: FUTAMURA SHINGO
IPC: B60C11/00
Filed: 1993-04-29
Abstract: An improved pneumatic tire having decreased rolling resistance employing at least one tire component selected from the group consisting of subtreads, black sidewall, body ply skims and bead fillers, prepared from a vulcanizable elastomeric composition having reduced hysteresis comprises from about 10 to 100 parts by weight of an elastomer comprising a plurality of polymer molecules, wherein substantially each polymer molecule contains at least one functional group at the site of initiation, and having a hysteresis reduction of at least about 10 percent compared to the same elastomer without a functional group on substantially each polymer molecule; from about 0 to 90 parts by weight of an elastomer having greater hysteresis than the elastomer having reduced hysteresis and selected from the group consisting of natural rubber, synthetic rubber and blends thereof; and, from about 20 to about 100 parts by weight of carbon black, per 100 parts of the elastomer. A method is also provided for reducing the rolling resistance of tires.
Patent CA-2099065-A1 (CA)
Title: Printing method and apparatus
Inventor: DEANGELIS ANDREW V
IPC: B42C19/06
Filed: 1993-06-23
Abstract: Abstract of the Disclosure A  method  and  apparatus  for  forming  books comprising pages of coated paper interspersed with pages of newsprint paper.  The book is formed by providing a moving web of coated paper, providing  a plurality of moving webs of newsprint paper, selectively perforating the moving web of coated paper in areas where coupons are to be provided, printing the moving web of coated paper with inks of a plurality of colors including printing within the coupon areas outlined by the perforating process, subjecting the moving web of coated paper to a heatset operation to set the inks on the web, printing the moving web of newsprint paper with at least one color ink,  and associating the moving webs of coated paper and newsprint paper in a pasting, folding, and cutting operation to form a plurality of books each comprising a plurality of pages of coated paper interspersed with a plurality of pages of newsprint paper and adhesively bound together along one longitudinal edge of the book and each including detachable coupons on at least some of the coated paper pages.
Patent CA-2099794-A1 (CA)
Title: Scraper for a Pipe Pig
Inventor: SIVACOE ORLANDE
IPC: B08B9/04
Filed: 1993-07-05
Abstract: A scraper for a pipeline pig. The scraper is made from a single metal blank, having a plurality of fins disposed radially about a common central axial member. Each fin includes a scraping end and a connector end. The connector end is connected to the common central axial member, and the scraping end extends circumferentially outward from the connector end. Each scraping end preferably forms a quarter circle, and the fins are connected in plural pairs to the common central axial member with adjacent pairs rotationally offset in relation to each other about the common central axial member, preferably about 45° apart. In use, the scraper is embedded in an elastic pig body.
Patent CA-2100902-A1 (CA)
Inventor: OGAWA KENJI
IPC: G01C19/72
Filed: 1993-07-20
Abstract: In a digital ramp phase type gyro in which a ramp signal RAM is produced by repeatedly accumulating step values sequentially generated corresponding to an input angular rate until the accumulated value exceeds a threshold value THR or -THR and the ramp signal RAM is used to modulate the phases of clockwise and counterclockwise light beams to cancel the phase difference therebetween, a comparing part 38 compares the threshold values THR and -THR and the ramp signal RAM and, when the ramp signal RAM exceeds either one of the threshold values THR and -THR, outputs the threshold value THR or -THR and a subtractor 41 subtracts the output threshold value from the accumulated value at that time, thereby causing a flyback of the ramp signal RAM. The output from a synchronous detector 23 at this time is latched as an error signal in a latch circuit 31 and the error signal is integrated by an integrating filter 32 to generate a correcting signal.  The correcting signal is added to a reference value Er in a circuit 37 to produce corrected threshold values THR and -THR and the phase difference between the clockwise and counterclockwise light beams immediately prior to the flyback is always held to be 2n.pi. rad.
Patent CA-2101044-A1 (CA)
Inventor: WILLEMOT JEAN-MARIE
IPC: A61M16/06
Filed: 1993-07-21
Abstract: ABRÉGÉ DESCRIPTIF L'équipement, notamment pour l'administration d'aérosols médicamenteux, comprend un dispositif de commande d'une vanne de distribution de gaz comprenant des dispositifs programmables, avantageusement individuels, de commande de séquences de fourniture de doses de gaz à l'utilisateur et des dispositifs d'enregistrement et de contrôle, avantageusement sur le même support individuel des séquences de fourniture effective de doses de gaz.
Patent CA-2102723-A1 (CA)
Title: Cold setting coating composition and process for comestible food products
Inventor: SAMSON ALLAN D
IPC: A23L17/00
Filed: 1993-11-09
Abstract: ABSTRACT OF THE DISCLOSURE           The present invention is a cold temperature activated batter used to coat fish portions cut from a uncooked, preformed, processed and frozen fish block and with cooked foods which are chilled before coating.  The latent cold temperature of the chilled food, which is preferably fish, is in the range of approximately -10° to 38°F, which activates the batter so as to cause it to gel or set on the fish portions and, as a result, the batter coating adheres evenly and uniformly to each fish portion.          After coating with the batter, the chilled fish portions may be also be coated with a toasted bread crumb before the batter sets, to form a bread coating mixture, in-situ, on the chilled fish portion. The bread crumbs may also include flavored oils derived from frying battered and fried fish or fried battered and breaded chicken in vegetable oils for the purpose of imparting savory and fried food flavor characteristics to the non-fried food.
Patent CA-2106508-A1 (CA)
Title: Diaphragm Assembly
Inventor: SAADI ROBERT E
IPC: E03D3/06
Filed: 1993-09-20
Abstract: A unitary diaphragm assembly for use in conventional flush valves. The diaphragm assembly has a flexible diaphragm which includes a seating portion and a mounting portion at the outer peripheral edge. A flow ring is positioned adjacent to the seating portion of the diaphragm. An elongated barrel member extends from the diaphragm in a longitudinal direction and includes a plurality of radial guides positioned circumferentially around the outer surface of the barrel member along a portion of the length of the barrel member. A second embodiment has a flexible diaphragm connected to a cylinder slide. The cylinder slide includes a longitudinal barrel member with a relief valve positioned in the interior of the lower portion of the barrel member.
Patent CA-2108677-A1 (CA)
Title: Process for melting down combustion residues in slag
Inventor: KUENSTLER JOHANN H
IPC: F23G5/00
Filed: 1993-02-11
Abstract: Instead of a complete incineration of waste, such as has hitherto been sought, firstly in a low temperature unit there is only a carbonization of the process material and sub-sequently concomitantly using carbonization materials or gases in a high temperature unit the temperatures necessary for melting the slag and complete combustion are obtained. In this way extraneous materials, heavy metals are received in the slag and can be permanently bound in. The conventional combustion zone is replaced by a generator for producing flammable carbonization gases, so that instead of an incinera-tion there is only a gasification of the charge. The gasification or carbonization can be randomly controlled. The residues left behind from carbonization contain more combustion energy than conventional, burnt-out residues and can be supplied to a slag fluidization process in the high temperature unit - a revolving cylindrical furnace being proposed here. The end product is completely burnt-out, fluidized slag, which can be left to solidify in random form.
Patent CA-2113099-A1 (CA)
Inventor: SHIH JESSIE W
IPC: C07K16/00
Filed: 1992-07-08
Abstract: Method for differentiating HTLV-I antibodies from HTLV-II antibodies, and peptides which enable the differentiation. Kits containing these peptides which allow for the differentiation between anti-HTLV-I antibodies and anti-HTLV-II antibodies.
Patent CA-2114103-A1 (CA)
Title: Device for detecting aqueous contaminants
Inventor: ROSSON REINHARDT A
IPC: C12Q1/68
Filed: 1992-07-30
Abstract: Device for detection of small quantities of a contaminant in water, comprising a light detecting means and a microorganism that emits significant detectable light only when exposed to a specific contaminant. Also, plasmid cassettes and host microorganisms containing such cassettes for use in the detection device.
Patent CA-2114250-A1 (CA)
Title: Use of relaxin in cardiovascular therapy and in the treatment of neurodegenerative diseases
Inventor: CRONIN MICHAEL
IPC: C07K14/64
Filed: 1992-08-18
Abstract: The invention concerns the use of relaxin or another compound capable of specific binding of a relaxin receptor in the heart in the cardiovascular therapy, and specifically in the treatment of acute and chronic heart failure or of a condition characterized by pathologically low heart rate. The invention further concerns the treatment of neurodegenerative diseases using relaxin or other compounds capable of selectively binding a relaxin receptor in the brain.
Patent CA-2114393-A1 (CA)
Inventor: MISIAK MICHAEL W
IPC: B23H9/12
Filed: 1994-01-26
Abstract: A method and apparatus for electrochemically machine lapping a matched set of fixed and orbiting scroll members for use in a scroll compressor. The orbiting scroll member is orbited in a short stroke relative to the fixed scroll member while an electrolyte is pumped between the scroll wraps. An electric current is passed through the fixed and orbiting scroll wraps to thereby electrochemically machine away high profile areas on corresponding metal wear surfaces. During the machining process, the clearance spacing between the scrolls is tightly controlled to prevent contact between the scrolls.
Patent CA-2115017-A1 (CA)
Title: 1-aryltriazolin(ethi)ones
Inventor: LINKER KARL-HEINZ
IPC: A01N43/84
Filed: 1994-02-04
Abstract: 1-Aryltriazolin(ethi)ones A b s t r a c t The invention relates to new 1-aryltriazolin(ethi)ones of the general formula (I)           (I) in which R1  represents nitro or represents a radical -NR8R9, R2  represents hydrogen, amino or cyano, or repre-sents  one of the radicals -R10,  -O-R10,  -S-R10, NR10R11,  -N(R11)-CO-R10 or -N=CR10R11, R3, R6 and R7  independently of  one another each represent hydrogen, halogen or nitro, R4  represents hydrogen, halogen, cyano or nitro, or represents  one  of  the  radicals  R12, -O-R12, -S-R12, -S(O)-R12, -SO2-R12, -SO2-OR12, -SO2-NR11R12, -CO-OR12,  -CO-NR11R12, -O-SO2-R12,  -N(R11)-SO2-R12, -NR11R12, -NH-P(O)(R11)(OR12) or -NH-P(O)(OR11)(OR12), R5  represents nitro, cyano, halogen or halogeno-alkyl, and X   represents oxygen or sulphur, where R8  and  R9  independently  of  one  another  each represent hydrogen or represent in each case optionally substituted alkyl, alkenyl, alkinyl, alkoxy,  cycloalkyl,  aryl or heterocyclyl,  or represent, together with the nitrogen atom to which they are attached, an optionally substi-tuted heterocycle, R10 represents in each case optionally substituted alkyl,  alkenyl,  alkinyl,  cycloalkyl,  aryl, arylalkyl or heterocyclyl, R11 represents hydrogen or represents in each case optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, arylalkyl or aryl, and R12  represents hydrogen or represents in each case optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aryl or heterocyclyl, to a number of processes for their preparation,  to a number  of  new  intermediates,  and  to  their  use  as herbicides.
Patent CA-2115167-A1 (CA)
Title: Apparatus and method for insuring and controlling turbulent flow for cleaning ducts
Inventor: PLUMMER RAYMOND G
IPC: B05B15/02
Filed: 1993-06-03
Abstract: This invention concerns a system for insuring and accurately controlling the turbulent flow of a pressurized mixture of a gas (14) and a cleaning fluid (12, 10) for purging and cleaning ducts. The pressures of cleaning fluid (12, 10) and the gas (14) are continuously sensed and transduced into electrical signals for controlling valves for the pressurized gas (14) to maintain and insure its pressure at a predetermined amount relative to the pressure of said cleaning fluid (12, 10) so that when the gas (14) and fluid are mixed in a turbulator (20), turbulent flow is insured. The improvements of this circuit include a pressure sensor transducer (52) for sensing the pressure of the input of the air (14) to the turbulator (20) and feeding it back to the main air pressure transducer (52) for accurately maintaining a predetermined ratio between the gas (14) and cleaning fluid (12, 10) pressures within less than about 1 psi in at least pressures of 150 psi.
Patent CA-2117392-A1 (CA)
Title: Docking Device for Portable Computer
Inventor: YAMAZAKI KAZUHIKO
IPC: G06F1/16
Filed: 1994-07-07
Abstract: To provide a docking device which can improve stereo effect and tone quality, and which allows a portable computer to have the same functions as a desktop personal computer, speakers are built into respective projecting portions projecting from the two sides along the width of a support portion of a main body.   This enables improvement  of  both  stereo  effect  and  tone  quality  from  a conventional case where speakers are incorporated in the main body facing the back.  Furthermore, it becomes possible to accommodate in the main body a full-size AT bus card which is difficult to accommodate conventionally.
Patent CA-2117753-A1 (CA)
Title: Corneal vacuum centering guide and dissector
Inventor: LOOMAS BRYAN
IPC: A61B17/30
Filed: 1993-04-07
Abstract: This invention is a surgical device for producing a generally circular, interlamellar pathway within the corneal stroma of the eye. The device is made up of three major components: a vacuum centering guide (50) having an inner bore (62) which fits at one end against the front of the eye, a barrel which fits within the inner bore of the centering guide and to which is attached the third major component, a generally circular dissecting ring. The dissecting ring (66) is shaped in such way that when an eye surgeon twists the barrel to which the ring is attached, the ring moves through the interlamellar space in the stroma producing the desired channel or pathway. The centering guide (62) may optionally include a ring having one or more pins which firmly engage the cornea's epiphilium. The constituent parts of the surgical device, particularly the dissecting ring, also form a part of this invention.
Patent CA-2120287-A1 (CA)
Inventor: NOBEL DOMINIQUE
IPC: C07C45/50
Filed: 1994-03-30
Abstract: La présente invention concerne la préparation d'acides carboxyliques ou des esters correspondants, par réaction d'un alcool avec du monoxyde de carbone en présence d'un catalyseur à l'iridium et d'un promoteur halogéné. La réaction est effectuée avec un mélange réactionnel dont la composition est maintenue pendant l'opération. Ledit mélange comprend entre 0 exclus et 10% d'eau, entre 0 exclus et 10% en promoteur halogéné, entre 2 et 40% d'ester correspondant à la réaction de l'alcool et de l'acide carboxylique précité, ledit acide carboxylique constituant le solvant de la réaction.
Patent CA-2121619-A1 (CA)
Inventor: JOCHUM PETER
IPC: B25C1/14
Filed: 1994-04-19
Abstract: An explosive powder charge operated setting tool contains a channel (7) located between an inner piston guide (2) for a piston (1) and an outer housing part (6). At the rear end of the tool, the channel (7) continues in a carrier (3) and can be in communication with a cartridge receptacle (4) in the carrier (3).      In its front region, the channel (7) is connected via a first opening (2c) in the piston guide (2) with a guide bore (2a) for the piston (1). Towards the rear end of the channel (7) there is a valve arrangement for forming a propellant gas storage space connected through the first opening (2c) to the guide bore (2a).      Propellant gases within the storage space are compressed by the piston (1) driven in the setting direction and, after completion of the driving or setting procedure, serve to return the piston (1) back into its rear starting position by expansion of the storage space gases. After the driving operation, a second opening (3a) communicating with the ambient atmosphere vents the space rearwardly of the piston (1) so that the piston (1) can move without interference back into the rear starting position and, in addition, any residual gases can escape through the second opening into the ambient atmosphere.
Patent CA-2121798-A1 (CA)
Title: Novel cytokine
Inventor: ARMITAGE RICHARD J
IPC: A61K47/48
Filed: 1992-10-23
Abstract: There is disclosed a polypeptide (CD40-L) and DNA sequences, vectors and transformed host cells useful in providing CD40-L polypeptides. More particularly, this invention provides isolated human and murine CD40-L polypeptides that bind to the extracellular binding region of a CD40 receptor.
Patent CA-2122153-A1 (CA)
Title: Mass spectrometry method using time-varying filtered noise
Inventor: KELLEY PAUL E
IPC: H01J49/42
Filed: 1992-09-28
Abstract: A method for performing mass analysis with dynamic mass resolution, in which a time-varying notch filtered broadband voltage signal (sometimes denoted as a time-varying "filtered noise" signal) is applied to a quadrupole mass filter (11-14). The time-varying filtered noise signal (22) can consist of a rapid sequence of static (time-invariant) filtered noise signals, each defining a notch having a selected width and center location. The invention facilitates performance of mass analysis over a wide range of ion mass-to-charge ratios ("mass ranges") with adequate mass resolution.  By appropriately choosing the width of each notch in the applied time-varying filtered noise, mass analysis can be performed with substantially constant mass separation over a wide mass range. In order to maintain substantially constant mass separation while analyzing a selected consecutive or non-consecutive sequence of ions (by passing such sequence of ions through the mass filter), the applied filtered noise (22) should have narrower notches at times when ions with higher mass-to-charge ratio are to be selected, and wider notches at times when ions with lower mass-to-charge ratio are to be selected.
Patent CA-2122935-A1 (CA)
Title: Apparatus and methods for clamping tissue and reflecting the same
Inventor: KENSEY KENNETH
IPC: A61B17/02
Filed: 1992-07-24
Abstract: A system and method of use for reflecting tissue located within the body of a living being. The system comprises at least one clip (20), a clip introducer instrument (100), a positioning member in the form of a tension cable assembly, and a clip removal instrument. The introducer instrument (100) is arranged for delivering the clip (20) through a small percutaneous incision or puncture to the situs of the tissue. The clip (20) has a pair of jaws (30, 32) defining a mouth (40) therebetween and are moveable between an open and a closed position. The jaws (30, 32) are biaised to the closed position by a biaising member (34) which is actuatable via the same or another percutaneous incision or puncture so that at least a portion of the tissue is trapped within the clip's mouth (40) when it closes. The tension cable assembly comprises a flexible cable (36) having a distal end portion and a proximal portion, and is of small diameter arranged to be extended through any percutaneous incision or puncture from outside the body of the being so that the distal end portion is coupled to the clip (20), with the proximal portion of the cable outside of the body of the being. The proximal portion of the cable is arranged to be moved to cause the portion of tissue trapped within the mouth (40) of the clip (20) to be moved to a desired position. The clip removal instrument is arranged to release the clip (20) from the tissue and to remove it from the being's body, if desired.