baber/WOPTO huggingface dataset:
Patent AU-2005254972-B2 (AU)
Title: Rapid production of oligonucleotides
Inventor: RICHMOND KATHRYN E
IPC: C12Q1/68
Filed: 2005-06-08
Granted: 2010-11-04
Abstract: A method of rapidly producing a double-stranded target DNA is disclosed. The method includes the step of producing multiple single stranded primary DNA constructs having (a) partially overlapping and complementary internal regions that together define the target DNA, and (b) flanking regions on either side of the internal regions containing a PCR primer recognition site and a restriction enzyme recognition site. The primary DNA constructs are amplified to form a pool of double-stranded primary constructs, and a restriction enzyme is used to cleave off the flanking regions. The target double-stranded DNA is then assembled from the cleaved fragments. Hundreds of thousands of oligonucleotides can be synthesized and quickly and efficiently assembled into many different individual double-stranded DNA target sequences using this method.
Patent AU-2005279741-B2 (AU)
Title: Degradable clostridial toxins
Inventor: ROGER AOKI KEI
IPC: C07K14/33
Filed: 2005-09-01
Granted: 2011-10-06
Abstract: The specification discloses modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; polynucleotide molecules encoding modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; and method of producing modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain.
Patent AU-2005310008-B2 (AU)
Title: Signal templates in implantable cardiac devices
Inventor: SUREKHA PALREDDY
IPC: A61B5/366
Filed: 2005-10-19
Granted: 2011-07-21
Abstract: The present invention is directed toward template formation methods for use in cardiac rhythm management devices. The template formation methods of the present invention provide for creating a robust template to compare with sensed cardiac complexes.
Patent AU-2006202360-B2 (AU)
Title: Applier with safety for implantable medical device
Inventor: UTH JOSHUA
IPC: A61M39/02
Filed: 2006-06-02
Granted: 2012-03-01
Abstract: Abstract An attachment mechanism for a surgically implantable medical device includes one or more fasteners which may be simultaneously moved from an undeployed position to a deployed position by operation of an integral actuator. The attachment mechanism may be configured to be deactuated, and the fasteners simultaneously moved from a deployed position to an undeployed position, allowing removal or repositioning of the medical device. An applier includes a locator for detachably holding the implantable medical device, locating it at the desired position, and actuating the attachment mechanism. The applier is configured to undeploy the attachment mechanism the implantable medical device can be detached from the body tissue. 0w
Patent AU-2006217534-B2 (AU)
Title: Oxyindole derivatives as 5HT4 receptor agonists
Inventor: HIROKI SONE
IPC: C07D401/14
Filed: 2006-02-10
Granted: 2011-08-11
Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, R , R, R , and R are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by 5-HT agonisitic activity such as, but not limited to, as gastroesophageal reflux disease, gastrointestinal disease, gastric motility disorder, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageral disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorders, cardiac failure, heart arrhythmia, diabetes or apnea syndrome.
Patent AU-2006223494-B2 (AU)
Title: Multi-clip device
Inventor: LEONARD ERICKSON
IPC: A61B17/128
Filed: 2006-03-08
Granted: 2011-09-01
Abstract: A multi-clip device for hemostasis includes an introducing tube (outer sheath) insertable into a body cavity. An operating wire is disposed within the introducing tube and is advanceable and retractable within the introducing tube. A plurality of detachable clips are arranged in a serial fashion within the introducing tube. Each clip has an engagement portion at the proximal end thereof and a plurality of arms extending towards the distal end thereof. The distal end of the operating wire engages the engagement portion of the proximal most clip, and the arms of the proximal most clip engage the engagement portion of the adjacent distally located clip. An expandable collar is slidably disposed about the arms of the clip and is configured such that when the collar is moved distally over the arms it closes and holds them in a closed position. The expandable collar has an expanding portion that is engaged by the distal end of t introducing tube so that the introducing tube can be used to advance the collar distally relative to the clip.
Patent AU-2006235487-B2 (AU)
Title: Nanoparticulate quinazoline derivative formulations
Inventor: GARY LIVERSIDGE
IPC: A61K9/14
Filed: 2006-04-12
Granted: 2011-12-22
Abstract: The present invention is directed to nanop articulate quinazoline derivative compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The nanoparticulate quinazoline derivative particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the treatment of hyperproliferative disorders, such as cancer and other neoplastic diseases. The compositions may include quinazomiamine derivatives such as erlotinib or a salt thereof.
Patent AU-2006243804-B2 (AU)
Title: Chemical clean for membrane filter
Inventor: ZHIYI CAO
IPC: B01D65/06
Filed: 2006-04-28
Granted: 2011-08-18
Abstract: A method of cleaning a porous polymeric membrane having a feed side and a permeate side including the steps of introducing a fluid containing a cleaning agent to the permeate side of a membrane allowing the cleaning agent to contact the permeate side of the membrane for a predetermined time, and contact the pores of the membrane, or introducing a fluid containing a cleaning agent to the feed side of a membrane; applying a transmembrane pressure to force the fluid containing the cleaning agent from the feed side to the permeate side of the membrane; allowing the cleaning agent to contact the permeate side of the membrane for a predetermined time, and contact the pores of the membrane. Preferably a concentration gradient between the feed side fluid and the lumen side fluid containing the cleaning agent causes cleaning agent to diffuse into the feed side fluid. Pressure may be applied to the fluid containing a cleaning agent to dislodge, where present, dissolved and undissolved solid from the membrane pores. The pressure may be applied in a pulsed fashion, and can be by way of compressed air at a pressure not more than the membrane's bubble point. The methods of the present invention may be preceded by, or followed with a backwash.
Patent AU-2006312406-B2 (AU)
Title: A game
Inventor: RANDALL STOLTEN MARK
IPC: A63F1/00
Filed: 2006-11-09
Granted: 2011-10-13
Abstract: The present invention relates to a set of cards for a game for at least two or more players when said player strategises to select the combination of criteria cards (from a pool of criteria cards) in which to use to obtain a points card. The points card requires at least two or more pool criteria cards for a player to obtain them. The win conditions include any one or more of a combination of cards. Each player holds their criteria related card or cards in either (a) an active state, (b) a spare state, and that a player qualifies for obtaining a point card if that player's active criteria related cards match to the criteria of the point cards.
Patent AU-2007246859-B2 (AU)
Title: Improvement of a dry powder inhaler
Inventor: PENTAFRAGAS DIMITRIOS
IPC: A61M15/00
Filed: 2007-05-09
Granted: 2012-11-29
Abstract: The present invention relates to an improvement of the mouthpiece of a dry powder inhalation device wherein the medicament is packed in the blisters of single dose blister strips. According to the invention a portion of the air which enters the mouthpiece does not pass through the powder containing blister, but follows an alternative path through the mouthpiece, enabling therefore the modification of the resistance of the device in a simple and cost effective manner.
Patent AU-2008200787-B2 (AU)
Title: Aqueous compositions and processes including fluorocarbons
Inventor: LAU WILLIE
IPC: C09D7/12
Filed: 2008-02-19
Granted: 2012-12-13
Abstract: An aqueous composition including: a) an aqueous medium; b) a polymer; c) from 0.03% to 1% by weight based on the weight of said polymer of a compound having the formula A-B-C-D wherein A is a 5 perfluoro group of the formula CF 3(CF 2)n wherein n is from 1 to 5, B is a hydrocarbon group of the formula (CH 2)m wherein m is from1to 4, C is a phosphate residue, and D is a cation, wherein said compound has a bioconcentration factor (BCF) from 1 to 1000 is provided. Processes for forming the aqueous composition and a polymeric coating are also 10 provided.
Patent AU-2008202862-B2 (AU)
Title: Novel MHC molecule constructs, and methods of employing these constructs for diagnosis and therapy, and uses of MHC molecules
Inventor: SOEREN BUUS
IPC: C12N5/071
Filed: 2008-06-30
Granted: 2011-09-29
Abstract: Novel compounds carrying ligands capable of ligating to counter receptors on relevant target cells are disclosed. The compounds possess a number of advantageous features, rendering them very suitable for a wide range of applications, including use as detection systems, detection of relevant target cells as well as in various methods. In particular, novel MHC molecule constructs comprising one or more MHC molecules are disclosed. The affinity and avidity of the MHC molecules of the constructs are surprisingly high. The possibility of presenting to the target cells a plurality of MHC molecules makes the MHC molecule constructs an extremely powerful tool e.g. in the field of diagnosis. The invention relates in general to the field of therapy, including therapeutic methods and therapeutic compositions. Also comprised by the present invention is the sample-mounted use of MHC molecules, MHC molecule multimers, and MHC molecule constructs.
Patent AU-2008209264-B2 (AU)
Title: Pharmaceutical compositions comprising nebivolol or a nebivolol analogue
Inventor: SHAH SHETAL
IPC: A61K31/353
Filed: 2008-01-22
Granted: 2014-11-27
Abstract: The disclosed pharmaceutical compositions for oral administration comprising as the active medicinal ingredient nebivolol, a nebivolol analogue or a pharmaceutically acceptable acid addition salt thereof and a wetting agent. The ratio of the wetting agent to the active ingredient is less than 0.025. The application also relates to methods of preparing these compositions and using said compositions for treating coronary vascular disorders in humans.
Patent AU-2008227993-B2 (AU)
Title: Synthetic closure with multiple internal layers, each layer having a variable cross section (VCS) along the closure length
Inventor: JOAQUIM ROMAO DE SOUSA JOSE
IPC: B65D39/00
Filed: 2008-03-14
Granted: 2011-12-08
Abstract: A container closure (17, 29) includes an inner core (19, 31) having a non-cylindrical profile created by a variable longitudinal cross-sectional area. One or more outer layers (21, 33) concentrically surround the core and have a cross-sectional area inversely correlated to the inner core so that the overall container closure has an essentially cylindrical profile.
Patent AU-2008311749-B2 (AU)
Title: Wireless in-band signaling with in-vehicle systems
Inventor: BIRMINGHAM KILEY
IPC: H04M3/42
Filed: 2008-10-20
Granted: 2013-01-17
Abstract: This invention pertains to methods and apparatus for data communications from vehicles, to obtain emergencies, concierge and other services, using a voice channel of a digital wireless telecommunications network. Signaling is described (FIG. 3) between a Server and an InΑ/βhicie System (FIG. 2) for commencing data sessions after establishing a voice channel call. Responsive to a predetermined signaling tone, a switch (PCM) mutes the speaker of the in-vehicie audio system. The call may be initiated from the vehicle automatically, and the call taker location may be unattended. Signaling methods are selected (FIGS. 4-5) for traversing both newer and legacy vocoders for ubiquitous operation.
Patent AU-2009201065-B2 (AU)
Title: Use of ranolazine for the preparation of a medicament for the treatment of arrhythmias
Inventor: BRENT BLACKBURN
IPC: A61P9/06
Filed: 2009-03-17
Granted: 2011-07-21
Abstract: Abstract Methods are provided for treating arrhythmias including tachycardias, such as idiopathic ventricular tachycardia, ventricular fibrillation, and Torsade de Pointes (TdP) in a manner that minimizes undesirable side effects.
Patent AU-2009206368-B2 (AU)
Title: Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors
Inventor: KOSTURA MATTHEW
IPC: C07D239/42
Filed: 2009-01-23
Granted: 2014-12-11
Abstract: The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-alpha or by PDE4, including but not limited to rheumatoid arthritis.
Patent AU-2009214641-B2 (AU)
Title: Crew transfer system
Inventor: COREY FLEISCHER
IPC: B63B27/14
Filed: 2009-02-12
Granted: 2011-12-08
Abstract: A crew transfer system for transferring personnel from a vessel to a stationary platform, such as an oil rig, is disclosed. In the illustrative embodiment, the system includes a ramp that is coupled to the vessel in such a way as to permit one translational and three rotational degrees of freedom at the vessel-end of the ramp. When the ramp couples to the stationary platform, the coupling permits no translational and only two rotational degrees of freedom.
Patent AU-2009216835-B2 (AU)
Title: Thermal machine
Inventor: VOGEL GREGORY
IPC: F23R3/04
Filed: 2009-02-11
Granted: 2013-12-05
Abstract: A thermal machine, in particular a gas turbine, comprises a hot gas duct (2) for transferring a hot gas stream (30). The hot gas duct (22) is delimited by a wall (21) that is externally surrounded by a cooling duct (20) inside which a cooling medium, especially cooling air, is conducted along the external face of the wall (21) from an inlet of the cooling duct (20) to an outlet, against the direction in which the hot gas flows (30). The cooling duct (20) is formed by the wall (21) of the hot air duct (22) and a cooling jacket (19) that is externally arranged at a distance from the wall (21). In order to better cool such a machine, a cooling baffle plate (28) is provided at the inlet of the cooling duct (20), cooling medium entering the cooling duct (20) through the cooling baffle holes of the cooling baffle plate (28) perpendicular to the wall (21) of the hot gas duct (22) and hitting the wall (21) of the hot gas duct (22). In order to reduce a transverse flow of the cooling medium in the cooling duct (20), the edge (48) of the cooling baffle plate (28) that is located at the inlet sealingly abuts the wall (21) of the hot gas duct (22).
Patent AU-2009227629-B2 (AU)
Title: Dosing regimen for a selective S1P1 receptor agonist
Inventor: SCHERZ MICHAEL
IPC: A61K31/00
Filed: 2009-03-12
Granted: 2014-09-04
Abstract: The present invention relates to a dosing regimen for a selective S1 P
Patent AU-2009235942-B2 (AU)
Title: Magnetic separation apparatus
Inventor: BAKER WILLIAM JOHN
IPC: B03C1/10
Filed: 2009-04-08
Granted: 2013-03-14
Abstract: A magnetic separation apparatus (10) for separating magnetic materials from non-magnetic materials in a material flow comprising self cleaning magnetic separators (15) comprising: a cylinder (20) having a first end closer to a material flow than its second end in use, a piston (25) slidingly mounted within the cylinder (20), and a magnetic shaft (30) extending from the piston (25), the piston (25) and cylinder (20) adapted to move the magnetic shaft (30) between an extended position (31) and a retracted position (32), such that in the extended position (32), at least a sleeveless portion of an outer surface of the magnetic shaft (30) is exposed to the material flow and in the retracted position the magnetic portion is retracted substantially or wholly within the cylinder (20), the apparatus including a protected shaft wiper (120) and shaft seal (125) within the first end of the cylinder (20) for removing extracted magnetics.
Patent AU-2009240884-B2 (AU)
Title: Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation
Inventor: KANEDA YASUFUMI
IPC: A61K35/36
Filed: 2009-04-30
Granted: 2014-02-13
Abstract: The following facts 1) to 3) are found; 1) when a tissue extract which is extracted from an isolated skin graft is administered intravenously, a bone-marrow-derived pluripotent stem cell can be induced in a peripheral blood; 2) the substance which can recruit the bone-marrow-derived pluripotent stem cell contained in the isolated skin graft into the peripheral blood is HMGB1; and 3) HMGB1 which has an activity to recruit the bone-marrow-derived pluripotent stem cell into the peripheral blood can be purified readily from cells in culture.
Patent AU-2009245565-B2 (AU)
Title: Titanium dioxide
Inventor: TEMPERLY JOHN
IPC: C09D7/61
Filed: 2009-05-01
Granted: 2014-02-13
Abstract: A coloured composition comprising: a) NIR scattering TiO
Patent AU-2009245824-B2 (AU)
Title: Method and apparatus for dynamically allocating H-ARQ process
Inventor: TERRY STEPHEN E
IPC: H04B7/212
Filed: 2009-12-07
Granted: 2012-12-06
Abstract: A method and apparatus for dynamically allocating hybrid automatic repeat (H ARQ) processes in a wireless transmit/receive unit (WTRU) for supporting enhanced uplink (EU) transmissions. The H-ARQ processes in the WTRU are reserved for specific transport channels (TrCHs), dedicated channel medium access control (MAC-d) flows or logical channels associated with different data transmission priority classes. The WTRU allocates H-ARQ processes from those reserved H-ARQ processes that are available. Optionally, a higher priority channel may be allowed to allocate an H-ARQ process reserved for lower priority channels. Lower priority H-ARQ processes may be pre-empted. The preemption may be restricted by urgency of data transmission, or by radio network controller (RNC) configuration of H-ARQ processes. Alternatively, a common pool of H ARQ processes may be configured and an H-ARQ process may be allocated from the common pool in accordance with a priority of each channel, and lower priority H-ARQ may be preempted. z a: C co~ C~l-X 0 c, co < - J 0' 0~ 0-
Patent AU-2009258050-B2 (AU)
Title: Fluid flow control device with retractable cannula
Inventor: SHAW THOMAS J
IPC: A61M5/00
Filed: 2009-03-20
Granted: 2015-06-18
Abstract: A device having a housing; a cannula projecting fon/vardly from the housing; a connector useful for attaching the device to a fluid source or receptacle; a fluid flow path establishing fluid communication between the cannula and the connector; a retraction mechanism biasing the cannula away from its projecting position; and an actuator supported by the housing and configured to modify the fluid flow path so as to terminate fluid flow through the device, seal off the fluid flow path, and release the retraction mechanism to retract the cannula into the housing. The subject device is particularly preferred for use in the medical field, for example, as part of an infusion set or as a collection device for blood, or other fluids or flowable matter.
Patent AU-2009314982-B2 (AU)
Title: Device for manufacturing absorptive article and method of manufacturing absorptive article
Inventor: YAMAMOTO HIROKI
IPC: A61F13/49
Filed: 2009-11-11
Granted: 2015-05-07
Abstract: An arm member (220) has a tip section (222) which is the pay-out position from which a string-like elastic member (6a’) is paid out, and the arm member (220) guides the elastic member (6a’).  The tip section (222) is alternately moved in a first direction (Da) which is the direction leading from the center of a web which comprises a series of parts each constituting a portion of an absorptive article (1) and is being conveyed in a predetermined direction, to a first end section (7a) in the intersecting direction (CD) intersecting the conveying direction (MD), and a second direction (Db) which is the direction leading toward a second end section (7b) which is the end section on the side opposite the first end section (7a).  This causes the elastic member (6a’) to be in contact with the web to lay the elastic member (6a’) thereon in a gathered corrugated pattern.  In this process, in a plan view of the composite web (7), when the nip point goes beyond the position at which the angle formed by the conveying direction (MD) and a line tangent to the gathered corrugated pattern, the distance between the tip section (222) and the nip point is set to be maximum.
Patent AU-2009315735-B2 (AU)
Title: Salts of fingolimod
Inventor: MUTZ MICHAEL
IPC: C07C215/10
Filed: 2009-11-10
Granted: 2013-01-10
Abstract: The present invention relates to salts, polymorphs and hydrates of 2-Amino-2-[2-(4-C
Patent AU-2009327753-B2 (AU)
Title: Apparatus for fixing a glass sheet for elevator's door
Inventor: YOON IL SHIK
IPC: B66B11/00
Filed: 2009-12-08
Granted: 2013-06-27
Abstract: The present invention relates to a fixing apparatus that makes it possible to easily attach/detach an ornamental glass sheet to the surface of an elevator door and provides an apparatus for fixing a glass sheet for an elevator door which includes: a rear sheet 10 that is made of an elastic material and disposed between the glass sheet 20, which is attached to the outer surface of the elevator door D, and the elevator door D to support the glass sheet 20; and a fixing means F that is installed along the edge of the glass sheet 20 and fixes the glass sheet to the elevator door D.
Patent AU-2009334868-B2 (AU)
Title: Nanoparticle contrast agents for diagnostic imaging
Inventor: COLBORN ROBERT EDGAR
IPC: A61K49/18
Filed: 2009-12-18
Granted: 2015-11-05
Abstract: Nanoparticles (10) functionalized with at least one zwitterionic moiety, and compositions comprising said nanoparticles are provided. The nanoparticles (10) have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle (10) comprises a core (20), having a core surface (30) essentially free of silica, and a shell (40) attached to the core surface (30). The shell (40) comprises at least one silane- functionalized zwitterionic moiety. Further, methods of making said nanoparticles and methods of their use as diagnostic agents are provided.