Patent SG-11201808231V-A (SG)
Title: Delivery system
Inventor: HNAT THOMAS
IPC: A61K9/16
Filed: 2017-03-31
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 1111111101111011101010111110101111101110101111100101111101101111101111011111 International Bureau 0.. .1 j (10) International Publication Number (43) International Publication Date ..... .....!;,' WO 2017/173269 Al 5 October 2017 (05.10.2017) IN I PO I P CT (51) International Patent Classification: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, A61K 9/06 (2006.01) A61K 47/06 (2006.01) HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, A61K 9/14 (2006.01) A61K 47/10 (2017.01) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, A61K 9/16 (2006.01) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (21) International Application Number: RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, PCT/US2017/025373 TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (22) International Filing Date: ZA, ZM, ZW. 31 March 2017 (31.03.2017) (84) Designated States (unless otherwise indicated, for every (25) Filing Language: English kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (26) Publication Language: English TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (30) Priority Data: TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, 62/316,064 31 March 2016 (31.03.2016) US DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, (71) Applicant: SMARTECH TOPICAL, LLC [US/US]; SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 11251 Rancho Carmel Dr., #502304, San Diego, California GW, KM, ML, MR, NE, SN, TD, TG). 92150-2304 (US). Declarations under Rule 4.17: (72) Inventor: HNAT, Thomas; 11251 Rancho Carmel Dr., — as to applicant's entitlement to apply for and be granted a #502304, San Diego, California 92150-2301 (US). patent (Rule 4.17(u)) (74) Agent: REITER, Stephen E.; Kilpatrick Townsend & as to the applicant's entitlement to claim the priority of the Stockton LLP, 1100 Peachtree Street, Suite 2800, Atlanta, Georgia 30309 (US). earlier application (Rule 4.17(iii)) Published: Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, — with international search report (Art. 21(3)) (81) — = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, Il C:r ei M IN ,—I (54) Title: DELIVERY SYSTEM Il C (57) : In accordance with the present disclosure, there are provided formulations comprising: (a) at least one active agent; ei (b) an oil, and optionally a thickener therefor; (c) an organic solvent, and a thickener therefor; and (d) an oil and/or solvent soluble 0 skin penetration enhancer; wherein: said formulation comprises < 10 wt % water; and said formulation optionally forms a thixotropic thinning gel. Also provided are gels comprising oil and organic solvent, methods for preparing same and methods for the topical de - .,. livery of an active agent to a subject in need thereof.