baber/WOPTO huggingface dataset:
Patent SG-10201806573T-A (SG)
Title: Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
Inventor: GALETTO ROMAN
IPC: A61K35/17
Filed: 2013-05-13
Abstract: METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR IMMUNOTHERAPY The present invention relates to methods for developing engineered T-cells for immunotherapy that are both non-alloreactive and resistant to immunosuppressive drugs. The present invention relates to methods for modifying T-cells by inactivating both genes encoding target for an immunosuppressive agent and T-cell receptor, in particular genes encoding CD52 and TCR. This method involves the use of specific rare cutting endonucleases, in particular TALE-nucleases (TAL effector endonuclease) and polynucleotides encoding such polypeptides, to precisely target a selection of key genes in T-cells, which are available from donors or from culture of primary cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections. Fig. 1
Patent SG-10201806665P-A (SG)
Title: Substrate polishing apparatus and method
Inventor: WATANABE YUKI
Filed: 2018-08-06
Abstract: SUBSTRATE POLISHING APPARATUS AND METHOD A substrate polishing apparatus includes: a top ring for pressing a substrate against a polishing pad; a press mechanism that independently presses a plurality of regions of the substrate; a spectrum generating unit that directs light onto a surface of the substrate to be polished, receives reflected light, and calculates a reflectivity spectrum corresponding to the wavelength of the reflected light; a profile signal generating unit that generates a polishing profile of the substrate when the reflectivity spectra at a plurality of measurement points on the substrate are input; a pressure control unit that controls pressing forces to be pressed against the plurality of regions of the substrate by the press mechanism based on the polishing profile; and an end detecting unit that detects an end of substrate polishing without being based on the polishing profile. Figure 6
Patent SG-10201810624R-A (SG)
Title: Modular integrated building and construction method thereof
Inventor: ROSANA WAI MAN WONG
IPC: E04B1/41
Filed: 2018-11-28
Abstract: Pageof 16 MODULAR INTEGRATED BUILDING AND CONSTRUCTION METHOD THEREOF 5 Disclosed herewith a modular integrated building and a construction method thereof. The building comprises multiple prefabricated room units (1), each provided with reserved, exposed reinforcing bars at its top. A bottom of a load - bearing structure 10 of the prefabrica ted room unit (1) is embedded with grouting couple shafts (2). Reinforcing bars of the load - bearing structure and of the prefabricated room unit (1) of a next floor are inserted in inner grouting chambers (21) of the grouting couple shafts (2) to connect t wo prefabricated room units (1) of adjacent floors together. A cast - in - situ concrete interlayer (3) is arranged for connecting adjacent prefabricated room units (1) 15 of a same floor together. According to the present invention , the on - site workload is reduc ed significantly , the construction period is shortened greatly, and the construction is convenient and rapid. (Fig. 12 ) 20
Patent SG-10201900563Y-A (SG)
Title: Systems and methods for mass calibration
Inventor: QUARMBY SCOTT T
Filed: 2016-03-21
Abstract: SYSTEMS AND METHODS FOR MASS CALIBRATION A method includes producing ions from one or more calibrant species and delivering the ions to a mass analyzer, and measuring a first set of mass related physical values for the ions from the one or more calibrant species. The method further includes producing ions from a sample and delivering the ions to a mass analyzer, and measuring a second mass related physical value for a first sample ion species. The first sample ion species has a mass-to-charge ratio outside of the range of the mass-to-charge ratios of the calibrant ion species. Additionally, the method includes calculating a calibration curve based on the first set of mass related physical values and second mass related physical value, and modifying at least one instrument parameter based on the calibration curve. Figure 1
Patent SG-10201901845Q-A (SG)
Title: Method for structuring a decorative of technical pattern in an object made of an at least partially transparent amorphous, semi-crystalline or crystalline material
Inventor: ALEXIS BOULMAY
Filed: 2019-03-01
Abstract: Method for structuring a decorative of technical pattern in an object made of an at least partially transparent amorphous, semi-crystalline or crystalline material 5 The invention relates to a method for structuring a decorative or technical pattern (22, 60) in the thickness of an object made of an at least partially transparent amorphous, semi-crystalline or crystalline material, the object made of an at least partially transparent material comprising a top 10 surface (18a) and a bottom surface (18b) which extends away from the top surface (18a), the method comprising the step consisting of providing at least one of the top (18a) or bottom (18b) surfaces of the object made of an at least partially transparent material with a mask (24) which defines at least one opening (25) whose outline corresponds to the profile of the decorative or 15 technical pattern (22, 60) to be structured, the mask (24) covering the at least one top (18a) or bottom (18b) surface of the object made of an at least partially transparent material at the positions which are not to be structured, the method also comprising the step which consists of structuring the decorative or technical pattern (22, 60) by means of a mono- or multicharged 20 ion beam (14) through the at least one opening (25) of the mask (24), the mechanical properties of the mask (24) being sufficient to prevent the ions of the ion beam (14) from etching the at least one top (18a) or bottom (18b) surface of the object made of an at least partially transparent material at the positions where this top (18a) or bottom (18b) surface is covered by the 25 mask (24). Figures 2A, 2B
Patent SG-11201806231P-A (SG)
Title: Measurement system, leg guide, jack-up platform
Inventor: RUTGERS JOCHEM
IPC: G01M5/00
Filed: 2017-01-23
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/126971 Al 27 July 2017 (27.07.2017) WIPO I PCT 111111111111110111011111111111010111110111011101111111111101111101111111110111111 W O 20 1712697 / 1 Al (51) International Patent Classification: E02B 17/02 (2006.01) G01L 1/04 (2006.01) E02B 17/08 (2006.01) G01L 3/00 (2006.01) G01M 5/00 (2006.01) E02B 17/00 (2006.01) (21) International Application Number: PCT/NL2017/050043 (22) International Filing Date: 23 January 2017 (23.01.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 2016138 22 January 2016 (22.01.2016) NL (71) Applicant: GUSTOMSC RESOURCES B.V. [NL/NL]; Karel Doormanweg 35, 3115 JD Schiedam (NL). (72) Inventors: RUTGERS, Jochem; c/o Karel Doormanweg 35, 3115 JD Schiedam (NL). HOFMAN, Andries Jo- hannes; c/o Karel Doormanweg 35, 3115 JD Schiedam (NL). (74) Agent: JANSEN, C.M.; V.O., Carnegieplein 5, 2517 KJ Den Haag (NL). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) = (54) Title: MEASUREMENT SYSTEM, LEG GUIDE, JACK-UP PLATFORM (57) : A measurement system that comprises at least one horizontal load measuring unit, that is preferably arranged on the leg guide is provided. The horizontal load measuring device measures or determines horizontal load on the position of the leg where the device is placed, which gives a more accurate indication of the leg bending moment than the rack phase differential measurement. Advantage- ously, multiple load measuring units can be provided along the leg guide.
Patent SG-11201808682X-A (SG)
Title: Silicone atoms containing ivacaftor analogues
Inventor: MUNOZ BENITO
IPC: C07F7/08
Filed: 2017-04-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 12 October 2017 (12.10.2017) WIPO I PCT (10) International Publication Number WO 2017/177124 Al 11111111111111011101111111111101011111011101011101111101110101111111111111110111111 (51) International Patent Classification: CO7D 215/56 (2006.01) A61K 31/695 (2006.01) C07F 7/08 (2006.01) A61P 11/00 (2006.01) (21) International Application Number: PCT/US2017/026579 (22) International Filing Date: 7 April 2017 (07.04.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/319,439 7 April 2016 (07.04.2016) US (71) Applicant: PROTEOSTASIS THERAPEUTICS, INC. [US/US]; 200 Technology Square, 4th Floor, Cambridge, MA 02139 (US). (72) Inventors: MUNOZ, Benito; 377 Lowell Avenue, New- tonville, MA 02460 (US). PARKS, Daniel; 1 la Orion Rd, Pepperell, MA 01463 (US). BASTOS, Cecilia, M.; 1 Bi- gelow Way, South Grafton, MA 01560 (US). (74) Agents: KAVANAUGH, Theresa, C. et al.; Goodwin Procter LLP, 100 Northern Avenue, Boston, MA 02210 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) W O 20 17177 / 124 Al (54) Title: SILICONE ATOMS CONTAINING IVACAFTOR ANALOGUES (57) : The present disclosure is directed to disclosed compounds that modulate e.g., address underlying defects in cellular processing of CFTR activity.
Patent SG-11201810059Q-A (SG)
Title: Disposal box for used playing cards
Inventor: SHIGETA YASUSHI
IPC: B65F1/00
Filed: 2017-05-09
Abstract: DISPOSAL BOX FOR USED PLAYING CARDS A disposal box (2) for used playing cards (1a) has a cuboid shape provided with six surfaces, namely, front and back surfaces, left and right surfaces, and upper and lower surfaces in an assembled state. The disposal box includes a slit (9) that is provided in at least one of the six surfaces and enables the used playing cards (1a) to be inserted into the disposal box, and further includes viewing windows (10) that are provided with a plurality of holes having a size at which the playing card cannot be taken out, and can allow the used playing cards contained in the disposal box to be visually recognized. The disposal box (2) is formed of a paper or plastic material, and can be discarded in a state in which the used playing cards (1a) are contained in the disposal box. Fig. 1
Patent SG-11201900016S-A (SG)
Title: 6-isopropyl-2,4-dimethylcyclohexen-1-ol compounds as fragrance ingredients
Inventor: LOVCHIK MARTIN ALAN
IPC: C11B9/00
Filed: 2017-07-27
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111111111111111111111111111111111111111111111111111111111111111111111111111111 Organization 0 International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/019935 Al 01 February 2018 (01.02.2018) WIP0 I PCT (51) International Patent Classification: C07C 35/18 (2006.01) A61Q 19/10 (2006.01) A61K 8/34 (2006.01) C11B 9/00 (2006.01) (21) International Application Number: PCT/EP2017/068999 (22) International Filing Date: 27 July 2017 (27.07.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1613013.0 27 July 2016 (27.07.2016) GB (71) Applicant: GIVAUDAN SA [CH/CH]; Chemin de la Par- fumerie 5, 1214 Vernier (CH). (72) Inventors: LOVCHIK, Martin Alan; Alte Gfennstrasse 14, 8600 Diibendorf (CH). ZELENAY, Veronika; Ueber- landstrasse 138, 8600 Diibendorf (CH). (74) Agent: GLOBAL PATENTS; Givaudan International SA, Uberlandstrasse 138, 8600 Diibendorf (CH). — Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (81) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (84) Published: with international search report (Art. 21(3)) — Il ir) M 01 01 Il 0 --.... 00 1-1 (54) Title: 6-ISOPROPYL-2,4-DIMETHYLCYCLOHEXEN-1-0L COMPOUNDS AS 0 FRAGRANCE INGREDIENTS ei (57) : The present invention refers to 6-isopropyl-2,4-dimethylcyclohexen- 1-01 derivatives, to a method of their production, 0 and fragrance compositions and fragranced articles comprising them.
Patent SG-11201910971Q-A (SG)
Title: Refrigerator
Inventor: NAKANISHI YUZO
IPC: F25D21/04
Filed: 2017-07-21
Abstract: KPO-3514 19 A refrigerator includes a main body including an opening portion; a door that opens and closes the opening portion of the main body; a door connecting portion connecting the door to the main body in an openable and closable manner; a heat dissipation pipe that is disposed in the main body and that dissipates heat; and an 5 outside air humidity sensor that is disposed in the door connecting portion in an upper portion of the door, the outside air humidity sensor measuring an outside air humidity. (Figure 2) 19
Patent AT-404368-B (AT)
IPC: D04H1/587
Filed: 1997-02-25
Granted: 1998-11-25
Abstract: The invention relates to a method for producing a reinforced fiber composite which contains cellulosic fibers, the cellulose being present in the crystalline structure cellulose II, by bringing said fiber composite into contact with an aqueous solution of N-methylmorpholin-N-oxide (NMMO) at an elevated temperature and subsequently washing said fiber composite. Said method is characterized in that the fiber composite is brought into contact with the aqueous solution in such a way that the reationship -947 + 0.30xlog(10)t + 0.046xT - 3.53xC + 645xlog(10)C where t is the time in minutes during which the fiber composite is kept in contact with the aqueous NMMO solution, T is the temperature of the aqueous NMMO solution in  DEG C and C is the concentration of the NMMO in % mass in relation to the aqueous NMMO solution, gives a figure in the region of 0.30 and 1.70 on the condition that the temperature T is less than 130  DEG C and the concentration C lies in the region of 70 to 84 % mass.
Patent DK-164592-B (DK)
Inventor: LEESON PAUL DAVID
IPC: C07C59/13
Filed: 1986-01-15
Abstract: Compounds of structure (I) 
<CHEM>
 in which, R<1> is -CH2CR<2>R<3>NR<4>R<5> or YCOR<6>; R<2> is hydrogen or C1-4alkyl; R<3> is hydrogen or -COR<6>; R<4> is hydrogen or C1-4alkyl; R<5> is hydrogen, C1-4alkyl or C1-4alkanoyl; R<6> is hydroxy, C1-4alkoxy, or -NR<4>R<5>; Y is a bond or C1-4alkylene; R<7> and R<8> are the same or different and are each hydrogen, halogen, C1-4alkyl, nitro or amino; X is oxygen, sulphur, or CH2; R<9> is hydroxy or a bioprecursor theri20; R<1><0> is hydrogen or C1-4alkyl; and Ar is 4-hydroxyphenyl, 5-hydroxy-2-pyridyl, 6-oxo-3(1H)-pyridyl or a 6-oxo-3(1H)-pyridazinyl group and pharmaceutically acceptable salts thereof, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy as antihyperlipidaemic agents.
Patent DK-143791-B (DK)
Title: Easily opened container with a detachable plastic stopper.
Inventor: KEHE A W
IPC: B32B3/24
Filed: 1974-01-18
Abstract: The invention involves an easily opened container involving a container surface with a superimposed layer of burnt-in lacquer, and with a separately produced opening which has a detachable plastic stopper, and which is heat sealed to the surface surrounding the surface of said container surface via a binding friendly plastic layer imposed on the layer of the burnt-in lacquer.Easily opened containers such as the type described above are well known. These containers are usually made of metal and are furnished with a pour opener, which commonly only takes up a part of the container's end surface. Until now, the pour opener has usually been formed by being stamped to the edge of a tear-strip. A pull-tab is fastened to the tear-strip, and by exertion of force; the pull-tab effects the separation of the tear-strip from the end surface along the perforated line.
Patent DK-159630-B (DK)
Inventor: BRODEN GERT
IPC: F23D14/42
Filed: 1986-02-14
Abstract: A device in a cutting torch which comprises a torch body with a valve housing and a nozzle and with a cutting oxygen duct, a heating oxygen duct and a combustion gas duct disposed in the torch, there being disposed in the torch a connection line which contains a throttling member between the heating oxygen duct and the cutting oxygen duct and wherein disposed in the cutting oxygen duct before the connection line is a valve member which permits a flow of heating oxygen to pass through the cutting oxygen duct only in the direction towards the orifice of the nozzle.The connection line between the heating oxygen duct and the cutting oxygen duct comprises at least one cooling oxygen duct (7) disposed in the nozzle which is elaborated with three sealing surfaces towards the torch body. The cooling oxygen duct (7) has a diameter which is so adapted in relation to the orifice diameter in the cutting oxygen duct of the nozzle and to the size of the heating flame that during heating of the workpiece a cooling oxygen pressure is rapidly built up in the cooling oxygen duct which prevents hot combustion gases from penetrating into the cutting oxygen ducts and that in the case of short nozzle distances to the workpiece the flow of cooling oxygen is prevented from becoming so great that the surface of the workpiece which is situated below the orifice of the cutting oxygen duct is cooled so rapidly that hole-piercing is rendered more difficult.
Patent HU-186224-B (HU)
Inventor: KESZLER JOZSEF
IPC: A01K1/02
Filed: 1982-02-02
Abstract: Die Erfindung bezieht sich auf eine Einrichtung zur Haltung von Kleintieren in Laboratorien. Durch die Erfindung koennen Kleintiere bzw. Versuchstiere unterschiedlicher Groesze staendig mit den fuer ihren Bedarf erforderlichen Frischwassermengen versorgt werden, wobei die Einrichtung einen einfachen, rationellen und wirtschaftlichen Betrieb erlaubt und eine ungehinderte Manipulation mit den Kaefigen, die die Tiere aufnehmen, gewaehrleistet. Das Wesen der Erfindung besteht in einer konstruktiven Verbesserung der aus einem Selbsttraenkventil, einem einheitlichen Kaefig, und Gestellsystem und einem Hoch- und Niederdruckwassernetz gebildeten Einrichtung. Durch Filter und einem geschlossenen Frischwasserkreislauf im Niederdruckwassernetz ist staendig Frischwasser verfuegbar, das den gestellten Hygieneanforderungen entspricht.
Patent HU-200934-B (HU)
Title: Herbal tea composition and process for producing it.
Inventor: CSATORDAI JOZSEF
IPC: A23F3/34
Filed: 1988-02-02
Abstract: A new type of herbal tea contains 10 to 30 % by weight of parsley fern flowers (Tanaceti flos), 10 to 30 % by weight of hawthorn tips (Crataegi flos cum foliis), 5 to 15 % by weight of citronella (Melissa oficinalis folium), and 25 to 75 % by weight of tonics, drugs, stimulants and vitamins. This new type of herbal tea stimulates sexual desire and is particularly effective in averting sexual impotence. Also described is a process for producing said tea.
Patent HU-217743-B (HU)
Title: Method for regulating of alight beam projected onto a rotating data carrier for nominal value during reading data and arrangement for realization said method
Inventor: FUELDNER FRIEDRICH
IPC: G11B7/095
Filed: 1991-09-06
Abstract: A process is disclosed for measuring or adjusting the radial and tangential angles of a light beam. In an optic reproduction device, such as a CD player, care must be taken that the data scanning light beam irradiates the disk as normal as possible. Because of the disk warp, however, the radial and tangential angles of the light beam change with each turn of the disk. Because of disk and device tolerances, the optical axis usually deviates from the normal. During reproduction, these deviations change. EP-PS 0 070 070 describes a costly optic measurement device to adjust the radial and tangential angles with respect to a fixed axis. In order to adjust the radial angle R and the tangential angle T of incidence of the light beam on the disk without additional measurement devices, the data signal (HF) is demodulated in an amplitude demodulator (DM). The adjustment signal UR = C * sin $g(f) * cos $g(a) for the radial angle R and the adjustment signal UT = - C * cos $g(f) * sin $(a) for the tangential angle T are derived from the amplitude C and the phase relation $g(f) of the demodulated data signal (M). The invention has applications in optic reproduction devices such as CD players, vido disk players and DRAW disk players, or in magneto-optic recording and reproduction devices.