baber/WOPTO huggingface dataset:
Patent WO-2019226709-A1 (WO)
Inventor: FRUCHTL MCKINZIE
IPC: C12P1/04
Filed: 2019-05-21
Abstract: La présente invention concerne des compléments nutritifs riches en protéines et des compléments alimentaires pour animaux dérivés d'un processus bactérien anaérobie qui sont générés par une multitude de processus de rupture cellulaire et de fractionnement/purification de protéines. L'invention concerne également des systèmes de fermentation bactérienne et des procédés d'obtention d'une ou de plusieurs parties contenant des protéines à partir d'un processus de fermentation à l'aide de substrats gazeux contenant du monoxyde de carbone augmentant le rendement en produit protéique à partir de cellules bactériennes. L'invention concerne en outre des compositions de compléments nutritifs riches en protéines ayant des utilisations utiles pour l'ingestion par plusieurs différents animaux et êtres humains.
Patent WO-2019241459-A1 (WO)
Title: System and methods for t1 and t2 weighted magnetic resonance imaging
Inventor: PAN JULLIE W
IPC: A61B5/055
Filed: 2019-06-13
Abstract: A magnetic resonance imaging method includes performing an inversion pulse sequence using an MRI system, the inversion pulse sequence producing an inversion recovery period, and during the inversion recovery period: (i) performing a longitudinal T2 encoding pulse sequence using the MRI system; (ii) acquiring a post longitudinal T2 encoding pulse sequence image signal block immediately following the longitudinal T2 encoding pulse sequence using the MRI system; and (iii) acquiring an additional image signal block either before the longitudinal T2 encoding pulse sequence or following the acquiring of the post longitudinal T2 encoding pulse sequence image signal block using the MRI system. The method further include generating calculated image data based on at least the post longitudinal T2 encoding pulse sequence image signal block using a self-correcting normalization image combination scheme.
Patent WO-2020036692-A1 (WO)
Title: Method and system for implementing split and parallelized encoding or transcoding of audio and video content
Inventor: KELLY JEREMY ROBERT
IPC: H04N21/2343
Filed: 2019-07-01
Abstract: Novel tools and techniques are provided for implementing split and parallelized encoding or transcoding of audio and video. In various embodiments, a computing system might split an audio-video file that is received from a content source into a single video file and a single audio file. The computing system might encode or transcode the single audio file. Concurrently, the computing system might split the single video file into a plurality of video segments. A plurality of parallel video encoders/transcoders might concurrently encode or transcode the plurality of video segments, each video encoder/transcoder encoding or transcoding one video segment of the plurality of video segments. Subsequently, the computing system might assemble the plurality of encoded or transcoded video segments with the encoded or transcoded audio file to produce an encoded or transcoded audio-video file, which may be output to a display device(s), an audio playback device(s), or the like.
Patent WO-2020037148-A1 (WO)
Title: Double auxotrophic mycobacterium and uses thereof
Inventor: JACOBS WILLIAM
IPC: A61K39/04
Filed: 2019-08-15
Abstract: Provided are attenuated strains of M. tuberculosis and M. bovis BCG which are double auxotrophic mutants with genes knocked out in the biosynthetic pathways for arginine and methionine, and compositions and methods of use thereof.
Patent WO-2020037235-A1 (WO)
Title: Solar receiver, selectively absorbing material, and associated fabrication methods
Inventor: LIU JIFENG
IPC: C01G3/02
Filed: 2019-08-16
Abstract: A selectively-absorbing material includes a silicone polymer and transition-metal oxide nanoparticles dispersed therein. Each of the transition-metal oxide nanoparticles includes manganese. A solar receiver includes (i) a metal substrate including an etched surface having a microroughness between 0.05 micrometers and two micrometers; (ii) a polymer matrix disposed on the etched surface; and (iii) transition-metal oxide nanoparticles dispersed within the polymer matrix. A method for producing transition-metal oxide nanoparticles includes recrystallizing a plurality of two-element nanoparticles at a temperature between 300 and 700 C. The plurality of two-element nanoparticles includes at least two of (i) copper oxide nanoparticles, (ii) manganese oxide nanoparticles, and (iii) iron oxide nanoparticles. A method for fabricating a selective-absorber includes etching a top surface of a metal substrate; depositing a polymer-matrix composite on the etched top surface; and interdiffusing the polymer-matrix composite and the metal substrate. The polymer-matrix composite includes transition-metal oxide nanoparticles dispersed therein.
Patent WO-2020055632-A1 (WO)
Title: System and method for controlling machines using operator alertness metrics
Inventor: EDWARDS DAVID J
IPC: G01C21/34
Filed: 2019-09-04
Abstract: A method includes determining a first task requiring one of a plurality of machines to traverse along a first route and determining a second task requiring the one of the plurality of machines to traverse along a second route. The method also includes determining a first route score for the first route, the first route score being at least in part indicative of a difficulty of traversing along the first route, and determining a second route score for the second route, the second route score being at least in part indicative of a difficulty of traversing along the second route. The method may also include receiving sensor data generated by a sensor associated with a first machine of the plurality of machines and determining, based at least in part on the sensor data, an alertness metric associated with an operator of the first machine. Based at least in part on the alertness metric being equal to or greater than a threshold alertness metric, the method may also include determining the first task for completion by the first machine or determining the second task for completion by the first machine. The method may also include sending, to an electronic device associated with the operator of the first machine, information about the first route or the second route; and receiving confirmation information indicative of the first machine traversing along the first route or of the first machine traversing along the second route.
Patent WO-2020061571-A1 (WO)
Inventor: LONDEI MARCO
IPC: C07K16/24
Filed: 2019-09-23
Abstract: Methods of treating asthma, including eosinophilic asthma, in a patient with an anti-IL-33 antibody, and methods of selecting asthma patients for anti-IL-33 therapy.
Patent WO-2020077073-A1 (WO)
Inventor: ABEYRATHNE CHATHURIKA
IPC: G01N27/403
Filed: 2019-10-10
Abstract: An ion sensor includes a substrate, at least one ion selective electrode deposited on the substrate, and a reference electrode deposited on the substrate. The sensor may further include an insulating layer placed over the ion selective electrode and the reference electrode and having openings for the ion selective electrode and the reference electrode, a microfluidic layer placed over at least part of the insulating layer, and a cover layer placed over the microfluidic layer. The reference electrode includes reference electrode material deposited on the substrate and a combination of a polymer and a chloride-containing salt deposited on the reference electrode material.
Patent WO-2020096904-A1 (WO)
Inventor: GAGE LAURA
IPC: C08K5/04
Filed: 2019-11-01
Abstract: Disclosed is an aqueous coating composition including at least one latex polymer derived from at least one monomer copolymerized or blended with a rhamnolipid and/ or sophorolipid biosurfactant, which in one embodiment is a mono- rhamnolipid. Also provided is an aqueous architectural coating composition including at least one latex polymer derived from at least one monomer copolymerized or blended with a biosurfactant, at least one pigment, and water.
Patent WO-2020097324-A1 (WO)
Inventor: FRANK DAVID
IPC: A61K31/403
Filed: 2019-11-07
Abstract: The present invention relates to compositions and methods for treating cancer with harmine.
Patent WO-2020106714-A1 (WO)
Inventor: ABDEL-MOHSEN MOHAMED
IPC: A61K38/45
Filed: 2019-11-19
Abstract: A method of reducing or inhibiting migration of HIV-infected CD4+ T cells to tissues comprises contacting the infected cells with a ligand that prevents or inhibits the interaction between a T cell-surface fucosylated glycan and its glycan-binding protein or with a molecule that metabolically inhibits glycosylation or fucosylation in said cell. In vitro and in vivo methods are described. Also described is a diagnostic method employing labeled ligands that bind a fucosylated glycan and provide a signal detectable by non- invasive imaging.
Patent WO-2020117988-A1 (WO)
Title: Inhibiteurs de cdk9 et leurs polymorphes destinés à être utilisés en tant qu'agents pour le traitement du cancer
Inventor: SIDDIQUI-JAIN ADAM
IPC: A61K47/12
Filed: 2019-12-04
Abstract: L'invention concerne une forme cristalline et/ou un polymorphe d'un composé ayant la structure suivante (I), y compris les formes tautomériques et zwittérioniques de celui-ci : L'invention concerne également des procédés associés à la préparation et à l'utilisation des polymorphes et des compositions pharmaceutiques les comprenant. L'invention concerne également des procédés de préparation d'un composé ayant la formule (I), ou un sel, un tautomère ou une forme zwitterionique de celui-ci.
Patent WO-2021118533-A1 (WO)
Inventor: JAESCHKE AXEL
IPC: E21B43/00
Filed: 2019-12-10
Abstract: An improved screw pump such as, for example, a twin screw pump is disclosed. In one embodiment, the screw pump includes a casing, first and second intermeshing rotors, and a liner positioned between the first and second rotors and the casing. In use, the liner is arranged and configured to bend and/or pivot in unison with the first and second rotors under the axial hydraulic pressure experienced by the screw pump during use. In one embodiment, the liner may be arranged and configured to include an asymmetric axial stiffness to facilitate bending of the liner. In another embodiment, the liner may be arranged and configured in multiple segments, the segments being arranged and configured to pivot to approximate the bending of the rotor shafts.
Patent WO-2020132605-A1 (WO)
Title: Organic compounds
Inventor: LI PENG
IPC: A61K31/4985
Filed: 2019-12-20
Abstract: The invention relates to particular substituted heterocycle fused gamma-carbolines, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving the 5-HT 2A  receptor, the serotonin transporter (SERT), pathways involving the dopamine D 1  and D 2  receptor signaling system, and/or the μ-opioid receptor.
Patent WO-2020142442-A1 (WO)
Inventor: LIU NANGUO
IPC: C08G77/46
Filed: 2019-12-30
Abstract: A branched organosilicon compound is provided having the general formula: (R 1  ) 3 - X-[SiR 2 0] n -SiR 2 R 3 . In the formula: each R is independently a substituted or unsubstituted hydrocarbyl group; each R 1  is selected from R and -OSi(R 4 ) 3 , with the proviso that at least one R 1  is -OSi(R 4 ) 3 ; each R 4  is selected from R, -OSi(R 5 ) 3 , and -[OSiR 2 ] m OSiR 3 ; each R5 is selected from R, -OSi(R 6 ) 3 , and -[OSiR 2 ] m OSiR 3 ; each R 6  is selected from R and - [OSiR 2 ] m OSiR 3 ; with the proviso that at least one of R 4 , R 5  and R 6  is -[OSiR 2 ] m OSiR 3 ; 0≤m≤100; X is a divalent linking group; 1 ≤n≤10; and R 3  has the general -D-O p -(C q H 2q O) r - R 8 . In R 3 , D is a divalent hydrocarbon linking group, subscript p is 0 or 1, subscript q is independently selected from 2 to 4 in each moiety indicated by subscript r, subscript r is from 1 to 500, and R 8  is selected from substituted or unsubstituted hydrocarbyl groups and H.
Patent WO-2020146267-A1 (WO)
Inventor: WU LIJUN
IPC: A61P35/00
Filed: 2020-01-06
Abstract: The present invention is directed to a monoclonal anti-human CD37 antibody or a single-chain variable fragment (scFv), comprising VH having the amino acid of SEQ ID NO: 3 and VL having the amino acid of SEQ ID NO: 7. The present invention is also directed to a chimeric antigen receptor fusion protein comprising from N-terminus to C-terminus: (i) a single-chain variable fragment (scFv) of the present invention, (ii) a transmembrane domain, (iii) at least one co-stimulatory domains, and (iv) an activating domain.
Patent WO-2020185294-A1 (WO)
Title: Method to detect real-time drilling events
Inventor: LOPES PEREIRA VITOR
IPC: E21B41/00
Filed: 2020-01-10
Abstract: A method for detecting the occurrence of an event at a well comprising: recording a first set of measurements collected from the well; processing the recorded measurements to provide a first set of data; calculating a first score based on the first set of processed data; recording a second set of measurements collected from the well; processing the second set of recorded measurements to provide a second set of data; calculating a second score based on the second set of processed data; wherein the first set of processed data and the second set of processed data is the number median of absolute difference from normal; combining the first score and the second score using a weighted average; and comparing the combined scores to a predetermined rule based on a specified time frame; and allowing an operator to adjust parameters of the well operation based on the score comparison.
Patent WO-2020159697-A1 (WO)
Inventor: ALON DAVID LOU
IPC: H04R1/02
Filed: 2020-01-14
Abstract: An audio system captures audio data of test sounds through a microphone of a headset worn by a user. The test sounds are played by an external speaker, and the audio data includes audio data captured for different orientations of the headset with respect to the external speaker. A set of head-related transfer function (HRTFs) is calculated based at least in part on the audio data of the test sounds at the different orientations of the headset. A portion of the set of HRTFs is discarded to create an intermediate set of HRTFs. The discarded portion corresponding to one or more distortion regions that are based in part on wearing the headset. One or more HRTFs are generated that correspond to the discarded portion using at least some of the intermediate set of HRTFs to create an individualized set of HRTFs for the user.
Patent WO-2020150673-A1 (WO)
Title: Serveur publicitaire programmatique
Inventor: SANTIAGO MARC
IPC: G06Q50/10
Filed: 2020-01-17
Abstract: L'invention concerne des systèmes, des procédés et des produits-programmes d'ordinateur destinés à la vente aux enchères d'un inventaire publicitaire destiné à diverses applications, y compris à des applications mobiles. Selon divers modes de réalisation, une requête de publicité est reçue au niveau d'un premier serveur à partir d'un dispositif client. La requête est envoyée, depuis le premier serveur, à au moins deux serveurs distants. Un montant d'offre et un actif à présenter au niveau du dispositif client sont reçus de la part de chacun des au moins deux serveurs distants. Une offre la plus élevée est déterminée à partir des montants des offres reçues. Il est déterminé si l'actif associé à l'offre la plus élevée est conforme sur la base de la requête. Lorsqu'il est déterminé que l'actif est conforme, l'actif est envoyé au dispositif client.
Patent WO-2020154359-A1 (WO)
Inventor: WU YUNTAO
IPC: C12N5/07
Filed: 2020-01-22
Abstract: Un dysfonctionnement immunitaire majeur persistant dans des maladies chroniques telles que l'infection par le VIH et le cancer est l'altération de la motilité des lymphocytes T et de la migration vers les tissus. Des agents thérapeutiques tels qu'une thérapie antirétrovirale ou une cancérothérapie ne restaurent souvent pas de manière complète la motilité de lymphocytes T pour la migration vers les tissus et l'infiltration des tissus. La cofiline est un facteur de dépolymérisation de l'actine qui régule la dynamique de l'actine pour la migration des lymphocytes T. Il est ici démontré que les niveaux de phosphorylation de cofiline dans les lymphocytes T sanguins (CD4 ou CD8), les macrophages, les lymphocytes B, les cellules tueuses naturelles (NK) et/ou les cellules cancéreuses peuvent être utilisées pour quantifier les dommages immunitaires provoqués par une infection virale chronique et le cancer, et pour prédire la récupération de lymphocytes T après un traitement.
Patent WO-2020172564-A1 (WO)
Title: Compositionally modified silicon coatings for use in a lithium ion battery anode
Inventor: YU CHENTAO
IPC: H01M4/04
Filed: 2020-02-21
Abstract: Provided herein are nanostructures for lithium ion battery electrodes and methods of fabrication. In some embodiments, a nanostructure template coated with a silicon-based coating is provided. The silicon coating may include a non-conformal, more porous silicon-rich SiEx layer and a conformal, denser SiEx layer on the non-conformal, more porous layer. In some embodiments, two different deposition processes are used: a PECVD layer to deposit the non-conformal, silicon-rich SiEx layer and a thermal CVD process to deposit the conformal layer. The silicon-rich SiEx material prevents silicon crystalline domain growth, limits macroscopic swelling, increases lithium diffusion rate and enhances significantly battery life during lithium ion battery cycle of charge and discharge.
Patent WO-2020176365-A1 (WO)
Title: Catheter and method of using a catheter
Inventor: BOUBES KHALED
IPC: A61M25/00
Filed: 2020-02-23
Abstract: Representative embodiments of a catheter, e.g., a dialysis catheter, and a method of use of the catheter, are disclosed. A representative catheter includes a catheter body and a balloon coupled to the catheter body. The catheter body includes first, second, and third ports, with the second port arranged spaced apart longitudinally from the first port; and first, second, and third lumens, the first lumen in fluid communication with the first port, the second lumen in fluid communication with the second port, and the third lumen in fluid communication with the third port. The balloon is arranged between the first and second ports, and is coupled to the third port. The balloon is inflatable using a fluid injected through a connecting tube and into the third lumen, helping to remove any fibrin sheath which may have formed around the first and second ports, and diminish recirculation of blood during dialysis.
Patent WO-2020176781-A1 (WO)
Inventor: RICE JEREMY
IPC: F28D21/00
Filed: 2020-02-27
Abstract: An enhanced gravity-driven, thin film condensation heat transfer condenser is disclosed for use in a thermosyphon performing in two perpendicular orientations, as well as orientations in between. The thermosyphon includes an evaporator fluidly coupled to a first condenser configured with a plurality of fins, with each of the plurality of fins having notches adjacent to flanges, the notches forming vapor flow channels through the plurality of fins. The first condenser is fluidly coupled to a second condenser, and vapor flowing from the evaporator must first pass through the first condenser before entering the second condenser.
Patent WO-2020185574-A1 (WO)
Inventor: KOBAN MARY E
IPC: F25B9/00
Filed: 2020-03-06
Abstract: A system and method for delivering a refrigerant to a refrigerant system. The system includes a distribution system comprising a distribution vessel, a transfer line, at least one pump, a distribution line and a distribution line branch arranged and disposed to transfer refrigerant from the distribution vessel to the refrigerant system. The system additionally includes a monitoring system comprising one or more sensors arranged and disposed to measure at least one distribution parameter within the distribution system and a recovery system arranged and disposed to selectively receive refrigerant based upon the refrigerant suitability for use in the refrigerant system.
Patent WO-2020186007-A1 (WO)
Title: Methods for cardiovascular disease in rheumatoid arthritis
Inventor: CURTIS JEFFREY R
IPC: G01N33/68
Filed: 2020-03-12
Abstract: This invention includes methods for assessing and treating risk of cardiovascular disease (CVD) in a subject with an inflammatory disease, for example rheumatoid arthritis (RA). Provided are methods for assessing risk, for recommending therapy, for prognosis and monitoring, and for treatment, which are advantageously accurate for CVD in RA. The methods include measuring quantitative data for biomarkers, calculating a CVD risk score for a subject using training data, and validating the CVD risk score with a set of validation clinical data.
Patent WO-2020190624-A1 (WO)
Title: High resolution real-time artistic style transfer pipeline
Inventor: PRINS ADAM
IPC: G06N3/04
Filed: 2020-03-12
Abstract: Systems and methods are provided for receiving at least one image and a reference image, and performing a plurality of downscaling operations having separable convolutions on the received at least one image. A plurality of residual blocks may be formed, with each residual block containing two separable convolutions of the kernel and two instance normalizations. A plurality of upscaling operations may be performed on the plurality of residual blocks, and a stylized image may be displayed based on at least the performed plurality of upscaling operations and the reference image.
Patent WO-2020191304-A1 (WO)
Inventor: IRKLIY ALEX
IPC: A47L9/28
Filed: 2020-03-20
Abstract: An adaptive sensor array system and method includes receiving one or more signals from a sensor array and compare the received signals to one or more object detection threshold values, determining if the robotic cleaner was moving along a travel path for a predetermined period of time, window W, in response to a determination that the robotic cleaner was operating in straight-line motion during the window W, calculating a value of the received detected signals from the sensor array during one or more calibration periods C of the window W, and adjusting one or more of the object detection threshold values based on the calculated value during the window W. A sum of all the calibration periods C during window W is less than a length of the window W. One of the calibration periods C may start at a beginning of the window W.
Patent WO-2020205714-A1 (WO)
Inventor: KOU ZHIFENG
IPC: A61B5/00
Filed: 2020-03-30
Abstract: A computer-implemented method for adjustable three-dimensional (3D) rendering of locations in a subject includes a step of receiving image data having a discrete spatial resolution for white matter tracts in a subject where the image data is generated by diffusion imaging. A first stereoscopic image is rendered on a display from the image data. The first stereoscopic image includes image parallax, which allows three-dimensional viewing. An input is received from a pointing device or a hand gesture that enables manipulation of the first stereoscopic image while maintaining proper three-dimensional spatial relationships. The pointing device interacts with the first stereoscopic image in three-dimensional space with six degrees of freedom.