baber/WOPTO huggingface dataset:
Patent NZ-504896-A (NZ)
Title: 3-{2-Oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]-naphthyridin-2-yl)propyl]imidazolidin-1-yl}propionic acid derivatives useful as integrin receptor antagonists
Inventor: PERKINS JAMES J
IPC: A61K31/4375
Filed: 1998-12-14
Abstract: A compound has one of the formula (I) to (7) and the pharmaceutically acceptable salts thereof wherein: the dotted line a is a single or a double bond, provided that when a is a double bond, the double bond carbon atoms are substituted only with R10 and R12; X is -C(=N-R1)-NR1R2, -NR1-C(=N-R1)-NR1R2 or an optionally substituted 5-or 6-membered monocyclic or 9-to 14-membered polycyclic aromatic or nonaromatic ring system having 1,2,3 or 4 heteroatoms selected from =N-, -NR1-, O, and S Y is -(CH2)m-, -(CH2)m-O-(CH2)n-, -(CH2)m-NR4-(CH2)n-, -(CH2)m-S-(CH2)n-, -(CH2)m-SO-(CH2)n-, -(CH2)m-SO2-(CH2)n-, -(CH2)m-O-(CH2)n-O-(CH2)p-, -(CH2)m-O-(CH2)n-NR4-(CH2)p-, -(CH2)m-NR4-(CH2)n-NR4-(CH2)p, -(CH2)m-O-(CH2)n-S-(CH2)p-, -(CH2)m-S-(CH2)n-S-(CH2)p-, -(CH2)m-NR4-(CH2)n-S-(CH2)p-, -(CH2)m-NR4-(CH2)n-O-(CH2)p-, -(CH2)m-S-(CH2)n-O-(CH2)p-, -(CH2)m-S-(CH2)n-NR4-(CH2)p- or -(CH2)m-Z-(CH2)n- with any methylene (CH2) carbon atom in Y, other than in R4, can be substituted by one or two R3 substituents Z is a 3-to 10-membered optionally substituted monocyclic or polycyclic aromatic or nonaromatic ring system having 0,1,2,3, or 4 heteroatoms selected from =N-, -NR1-, O, and S; R1 and R2 are each independently hydrogen, halogen, alkyl, cycloalkyl, cycloheteroalkyl, cycloalkyl-alkyl, cycloheteroalkyl-alkyl, aryl, arylalkyl, amino, aminoalkyl, acylaminoalkyl, acylamino, (alkyl)pamino, (alkyl)pamino- alkyl, alkoxy, alkoxyalkyl, hydroxycarbonylalkyl, alkoxycarbonyl, alkoxycarbonyl alkyl, hydroxyarbonyl alkoxy, hydroxy,  hydroxyalkyl, alkyloxyalkyl, nitro, cyano, trifluoromethyl, trifluoromethoxy, trifluoroethoxy, alkyl-S(O)p, (alkyl)paminocarbonyl, (alkyl)paminocarbonyloxy, alkyloxycarbonylamino, (arylalkyl)pamino, (aryl)pamino, arylalkylsulphonylamino, or alkylsulphonylamino or  two R1 substituents, when on the same carbon atom, are taken together with the carbon atom to which they are attached form a carbonyl group; R3 to R12 are as defined in the specification;, each m and n is independently an integer from 0 to 6; each p is independently an integer from 0 to 2 and  each v is independently an integer from 0 to 2.  A pharmaceutical acceptable composition thereof is useful for eliciting an integrin receptor antagonizing effect in a mammal in need thereof such as inhibition of bone resorption, restenosis, angiogenesis, diabetic retinopathy, macular degeneration, inflammation, viral disease, tumor growth, and metastasis.
Patent NZ-505063-A (NZ)
Title: Pharmaceutical use of long pentraxin PTX3 in treating tumour conditions
Inventor: BOTTAZZI BARBARA
IPC: A61P31/04
Filed: 1998-12-16
Abstract: Described are pharmaceutical compositions containing a long pentraxin PTX3, particularly human PTX3, for the therapy of infectious and inflammatory diseases or tumours.  Also described are expression vectors containing cDNA coding for PTX3; recombinant host cells transfected with such vectors; a method for producing substantial amounts of PTX3 involving the culturing of such cells, and the use of the vectors in the gene therapy of tumours.
Patent NZ-506940-A (NZ)
Title: Foot support in form of wedge in section to support first toe and first metatarsal
Inventor: ROTHBART BRIAN A
IPC: A43B7/24
Filed: 1998-08-14
Abstract: A foot support system (60) for supporting a hyperpronating foot (20) both dynamically while the foot (20) is in motion and statically is disclosed. The foot support system (60) is a bed upon which the foot (20) rests which includes an inner edge (62) and an outer edge (64). The foot support system (60) is positioned underneath the medial column of the forefoot of foot (20). The foot support system (60) laterally decreases in thickness from the inner edge (62) to the outer edge (64). The inner edge (62) is positioned along the medial side of the foot (20), and the outer edge (64) is positioned longitudinally in a zone adjacent to a lateral margin of the hallux (48), the proximal phalanx , and the first metatarsal and a medial margin of the phalanges of the second toe and the second metatarsal.
Patent NZ-509595-A (NZ)
Title: Peg-urate oxidase conjugates and use thereof
Inventor: WILLIAMS L DAVID
IPC: A61K47/48
Filed: 1999-08-02
Abstract: A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75 % of the uricolytic activity of the unmodified enzyme.
Patent NZ-513433-A (NZ)
Title: Benzoheterocycles, their use as MEK inhibitors and use in treating proliferative diseases such as cancer
Inventor: BARRETT STEPHEN DOUGLAS
IPC: C07D249/18
Filed: 1999-12-21
Abstract: Compounds of formula (I) are described; wherein W is OH, or derivatives of the carboxylic acid, and Q is a heterocyclo-condensed ortho-phenylene residue.  These compounds are useful as MEK inhibitors, particularly in medicaments for the treatment of proliferative diseases such as cancer.
Patent NZ-514380-A (NZ)
Title: C7 carbonate substituted taxanes as antitumor agents
Inventor: HOLTON ROBERT A
IPC: C07D407/12
Filed: 2001-02-02
Abstract: Disclosed are taxanes of formula (I), wherein: R2 is acyloxy, R7 is R7aOCOO-, R7a is optionally substituted hydrocarbyl or heterocyclo, R9 is keto, hydroxy, or acyloxy, R10 is hydroxy, R14 is hydrido or hydroxy, X3 is optionally substituted alkyl, alkenyl, alkynyl, phenyl or heterocyclo, X5 is -COX10, -COOX10 or -CONHX10, X10 is optionally substituted hydrocarbyl or heterocyclo, and Ac is acetyl. The taxanes are used in the manufacture of medicaments for inhibiting tumour growth in a mammal.
Patent NZ-519319-A (NZ)
Title: Intermittently bonded nonwoven disposable surgical laminates
Inventor: ANKUDA EDWARD
IPC: A41D31/02
Filed: 2000-11-13
Abstract: Disposable surgical drapes and gowns (10) exhibiting desirable softness, foldability, absorbency and breathability characteristics incorporating cluster bonded nonwoven laminates. Film layers (12) and nonwoven web layers (14) are secured together by spaced apart unbounded adhesive clusters (16). Each adhesive cluster includes a perimeterless grouping of discrete spaced apart adhesive droplets (18). A method and modified apparatus for making the cluster bonded laminates is also described.
Patent NZ-532311-A (NZ)
Title: Nickel hydrogen battery
Inventor: WILLSON CHRISTOPHER D
IPC: H01M50/195
Filed: 2002-10-09
Abstract: An electrochemical cell comprises a plurality of cell components including at least a positive electrode, a negative electrode, a separator, and a current collector; and a plastic seal component (102) secured about a periphery of at least one of the cell components wherein the plastic seal component includes a plastic material and a filler material having a higher thermal conductivity than the plastic material. The cell can be a nickel hydrogen electrochemical cell. An electrochemical battery comprises a plurality of electrochemical cells as described above.
Patent NZ-532412-A (NZ)
Title: Macrolides containing pharmaceutical compositions
Inventor: MEINGASSNER JOSEF GOTTFRIED
IPC: A61P17/00
Filed: 2002-10-22
Abstract: Disclosed is a pharmaceutical composition comprising a compound of formula (I) and a pharmaceutically acceptable 2-amino-1,3-propanediol beside one or more pharmaceutically acceptable excipient(s).
Patent NZ-537314-A (NZ)
Title: New 3-(4-oxo-4H-chromen-2-yl)-(1H)-quinoline-4-one compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: BRION JEAN-DANIEL
IPC: C07D405/14
Filed: 2003-06-18
Abstract: Disclosed herein are 3-(4-oxo-4H-chromen-2-yl)-(1H)-quinoline-4-one compounds of formula (I), optical isomers, if any, hydrates, solvates, addition salts and pharmaceutically acceptable acids thereof, wherein: R1, R2, R3, R4, R6, R8, R9 and R10, which may be same or different, each represent a group selected among hydrogen, hydroxy, alkoxy, alkyl, arylalkoxy, alkoxycarbonylalkoxy and OR' wherein R' represents an ionized or ionizable group; R5 represents a group selected among alkyl, aryl and heteroaryl; R7 represents a group selected among hydrogen, hydroxy, alkoxy, alkyl and cycloalkyl, or R7 represents a nitrogenous or oxygen-containing heterocycle. These compounds are suitable for use in an anti-cancer medicament for treating cancer.
Patent NZ-537530-A (NZ)
Title: Sealing cap
Inventor: PICTON DAVID JOHN
Filed: 2004-12-24
Abstract: A sealing cap which has a substantially cylindrically shaped inner wall surface with one end (4) closed and the other end (3) open; having an internal threaded portion (6) on the inner wall and having an annular sealing rib (16) on the internal surface of the closed end concentric with the axis of the threaded portion and projecting towards the open end of the cap, and grip means on the outer wall surface.
Patent NZ-540703-A (NZ)
Title: Carved pearl
Inventor: HUYNH CHI
IPC: A44C17/00
Filed: 2003-12-10
Abstract: Carved pearls 10 and methods of their manufacture are disclosed. A mollusc is seeded with at least one nucleus 11 and the mollusc's natural defences deposit a nacre coating 12 on the nucleus to a preferred thickness. The nacre coating is then carved so that a portion of the nucleus is exposed. In a further embodiment the nucleus is a gem of a different colour to the nacre coating.
Patent NZ-543014-A (NZ)
Title: Method for production of 4,10beta-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1,13alpha-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene
Inventor: DIDIER ERIC
IPC: C07D305/14
Filed: 2004-04-13
Abstract: The disclosure relates to a method for the production of 4,10beta-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1,13alpha-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene of formula (I) from 4-acetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1,13alpha-dihydroxy-9-oxo-7beta-trifluoromethylsulfonyloxy-tax-11-ene by reaction with a molecular sieve in sulpholane.
Patent NZ-544120-A (NZ)
Title: Hand-held cordless vacuum cleaner
Inventor: MILLIGAN MICHAEL
Filed: 2004-10-14
Abstract: A hand-held portable vacuum includes a housing having a handle 150a, a dirt cup having an inlet and defining a container for storage of dirt and debris, the dirt cup being removably attached to the housing and an impeller at least partially disposed in the housing. A filter 414 is disposed between the impeller and the inlet, the filter 414 being formed with a plurality of pleats. A filter cleaning device is coupled to at least one of the housing and the dirt cup, and includes at least one rib and a hub 304. The hub 304 is coupled to one of the filter 414 and the rib, and is configured to rotate the one of the filter 414 and the rib about the other one to generate contact to at least partially dislodge accumulated dirt and debris from the pleats.
Patent NZ-544454-A (NZ)
Title: Imidazole derivatives III
Inventor: BUETTELMANN BERND
IPC: A61P25/00
Filed: 2004-07-01
Abstract: A compound of the general formula I wherein: R1 signifies halogen, lower alkyl, lower alkoxy, CF3, CF2H, OCF3, OCF2H, or cyano; R2 signifies lower alkyl or cycloalkyl; R3 signifies lower alkyl, cycloalkyl, -(CH2)n-cycloalkyl, -(CH2)n-CN or -(CH2)n-O-Iower alkyl, lower-alkoxy aryl, Fn-R5, wherein R5 is lower alkyl or lower alkenyl; n is 1, 2 or 3; and R4 is hydrogen, C(O)H, or CH2R5 wherein R5 is hydrogen, OH, C1-C6-alkyl, C3 -C12- cycloalkyl; as well as to pharmaceutically acceptable salts thereof.
Patent NZ-548257-A (NZ)
Title: Modified human growth hormone polypeptides and their uses
Inventor: CHO HO SUNG
IPC: C12Q1/68
Filed: 2005-01-28
Abstract: Disclosed is a human growth hormone (hGH) polypeptide comprising a non-naturally encoded amino acid (NEAA) comprising a carbonyl functional group, wherein said NEAA is positioned at a following position of hGH comprising the amino acid sequence set forth in SEQ ID NO:2: (i) at the N-terminus; (ii) within residues 10-31; (iii) within residues 35-74; (iv) within residues 86-95; (v) within residues 97-102; (vi) within residues 111-119; (vii) within residues 134-146; (viii) within residues 155-176; and (ix) at the C-terminus.
Patent NZ-550686-A (NZ)
Title: Decontamination system
Inventor: GREEN BRUCE PHILIP
IPC: A61B19/00
Filed: 2004-07-26
Abstract: Disclosed is a decontamination system suitable for decontaminating items of medical equipment such as endoscopes, the system comprising; (I) a plurality of pre-clean wipes comprising moist fabric members for wiping an item to be decontaminated; (II) a two-part sterilant system comprising: (a) a first part comprising a first reagent in a carrier medium; and (b) a second part which is miscible with the first part and which comprises a second reagent in a carrier medium; wherein the first reagent and the second reagent will react when mixed to provide a sterilising composition; the first part being contained in a dispenser whereby it may be dispensed as a fluid, and the second part being absorbed or impregnated in a plurality of sterilising wipes each of which comprises a fabric member in a sealed container; and (III) a plurality of rinse wipes, each rinse wipe comprising a moist, sterile, fabric member in its own sealed container.
Patent NZ-554047-A (NZ)
Title: Peripheral unit control system, particularly to be employed in a motor vehicle
Inventor: POLIZZI GIANFRANCO
Filed: 2005-09-02
Abstract: A peripheral unit control system is disclosed. The control system is for use in a motor vehicle and includes a control unit, an actuation unit and supply means for the control unit and the actuation unit. The control unit is connected with peripheral units and with the actuation unit, and includes actuation means selecting the peripheral units, the actuation unit including interaction and/or visualization means for interacting with the selective actuation means by signals to activate and/or deactivate at one of the peripheral units.
Patent NZ-555705-A (NZ)
Title: A method for producing cheese using heat treated milk and a protein hydrolysate
Inventor: FOLKERTSMA BAUKJE
IPC: A23C19/055
Filed: 2005-12-21
Abstract: Disclosed is a method of producing curd or cheese from a milk composition, comprising the following steps: heating milk resulting in a degree of whey denaturation of at least 30%, adding to the heat treated milk a protein hydrolysate, and/or a peptide and/or a mixture of peptides, wherein said peptide and/or mixture of peptides comprises a peptide which has a net negative charge at pH 6.5 or which comprises Lys-Lys residue, adding to the heat treated milk a coagulant to form a gel, and processing the formed gel into a cheese curd and separating the whey from the curd.
Patent NZ-562393-A (NZ)
Title: Linking an imitation cigarette with viewing device to display images of smoking
Inventor: KOBAL GERD
IPC: A24F42/60
Filed: 2006-05-30
Abstract: Disclosed is a virtual or augmented reality smoking system (200) to imitate the physical and/or sensorial pleasures of smoking. The system comprises a smoking implant shaped device (300), an image generator (500), and a viewing device (400). The viewing device is capable of displaying images from the image generator in conjunction with the smoking implement shaped device.
Patent NZ-568360-A (NZ)
Title: Metal substrate for a high-temperature superconducting thin-film strip conductor (HTSL-CC)
Inventor: SCHNELLER THEODOR
IPC: H01L39/24
Filed: 2008-05-19
Abstract: Disclosed is a method for processing a biaxially textured metal substrate as a starting material for a high-temperature superconducting thin-film strip conductor (HTSL-CC), comprising the metal substrate, a buffer layer chemically generated thereon and grown crystallographically unrotated in relation to the metal substrate, and a chemically generated superconducting coating thereon, wherein a superstructure of the metal substrate is removed before the generation of the buffer layer. Also disclosed is a high-temperature superconducting thin-film strip conductor (HTSL-CC), comprising a metal substrate, a buffer layer chemically generated thereon and grown crystallographically unrotated in relation to the metal substrate, and a chemically generated superconducting coating thereon, wherein the metal substrate has a surface roughness RMS <50 nm, and the buffer layer is grown directly on its surface, without an intermediate layer, crystallographically unrotated in relation to the crystalline structure of the metal substrate.
Patent NZ-568446-A (NZ)
Title: Lactam compounds and methods of using the same as modulators of 11-beta hydroxyl steroid dehydrogenase 1
Inventor: ZHUO JINCONG
IPC: A61K31/4015
Filed: 2006-12-04
Abstract: Disclosed herein is a 2,8-diazaspirl[4.5]decan-1-one compound of formula III, wherein the substituents are as defined with in the specification, processes for their preparation and compositions comprising said compounds. Such compounds are useful in the treatment of obesity, diabetes, glucose intolerance, insulin resistance, hyperglycemia, atherosclerosis, hypertension, hyperlipidemia, cognitive impairment, dementia, depression, glaucoma, cardiovascular disorders, osteoporosis, inflammation, metabolic syndrome, coronary heart disease, type 2 diabetes, hypercortisolemia, androgen excess, or polycystic ovary syndrome (PCOS).
Patent NZ-572053-A (NZ)
Title: A U shaped anchor to be set in concrete to enable connection to the reinforcement in another concrete slab
Inventor: IRELAND BRUCE IAN
IPC: E04C5/16
Filed: 2007-04-19
Abstract: A concrete construction using headed loop anchors (10) to join precast panels together. Each anchor has a 'U' shaped section with parallel spaced legs. The free ends have heads. The headed loop anchor is formed by bending and then forging the head from the legs so the anchor is an integral unit. In use, the headed loop anchors are positioned in parallel spaced relation so that the looped sections project from a slab so that a suitable connector (21, 24) may be used to hook over the loop sections in order to connect adjacent concrete sections together. A rebate form work including a box holding the anchors in spaced apart relation is also disclosed. The box has a back wall through which loop sections of the respective anchors project into the box and legs of the respective anchors project out of the box. A removable cover closes the box and may be removed to expose the loops inside the box. Additionally a method of construction is also discussed.
Patent NZ-578808-A (NZ)
Title: Winch drum assembly and method for spooling a line
Inventor: CRAWFORD ALEXANDER CHARLES
IPC: B66D1/38
Filed: 2008-02-01
Abstract: Disclosed is a winch drum assembly which includes a barrel adapted to receive a line and a spooling device for guiding the line onto the barrel. The barrel and the spooling device rotate relative to one another such that the line is wound onto the barrel at a point that moves axially with respect to the barrel. The axial direction of the line spooled onto the barrel is adapted to change at least once per revolution of the barrel with respect to the spooling device. The line is adapted to be spooled onto the barrel in a first axial direction when the barrel is in its first half cycle between 0° and 180°, and the line is adapted to be spooled onto the barrel in a second axial direction when the barrel is in the second half of the cycle of the barrel between 180° and 360°. Axially adjacent rows of line are spooled onto the barrel parallel to one another.
Patent NZ-582916-A (NZ)
Title: Immunoglobulin cleavage fragments as disease indicators and compositions for detecting and binding such
Inventor: JORDAN ROBERT
IPC: C07K16/18
Filed: 2008-08-04
Abstract: Disclosed are antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions. The antibodies in question are restricted to antibodies that will bind to IgG cleavage products but not to intact IgG.
Patent NZ-587556-A (NZ)
Title: Preventing blocking of SCR catalyst by removing large ash from the flue gas and reintroducing it later
Inventor: IANNACCHIONE STEVEN
IPC: B01D39/10
Filed: 2010-08-24
Abstract: A method and apparatus for preventing the plugging, blockage and/or contamination of an SCR catalyst is disclosed. The invention relates generally to the field of emission control equipment for boilers, heaters, kilns, or other flue gas or combustion gas, generating devices (e.g., those located at power plants, processing plants, etc.). In one embodiment, the method and apparatus of the invention is designed to protect an SCR catalyst from plugging and/or blockage from large particle ash that may be generated during combustion by removing the large ash from the flue gas and reintroducing it later.
Patent NZ-592882-A (NZ)
Title: Mucoadhesive film comprising testosterone and cellulose derivatives
Inventor: KRUMME MARKUS
IPC: A61P5/30
Filed: 2006-03-15
Abstract: Disclosed is a mucoadhesive film consisting of 0.01-50% by weight of an androgen selected from testosterone, 7?-methyl-19-nortestosterone, 7?-methyl-11?-fluoro-19-nortestosterone and a combination thereof, and 50-99.99% by weight of a carrier material selected from the group consisting of methylcellulose, ethylcellulose, hydroxypropylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose and a combination thereof, wherein said androgen is dissolved in said carrier material and wherein the mucoadhesive film completely dissolves in the mouth within 30 minutes and releases said androgen on buccal application. Also disclosed is a film casting process for producing the mucoadhesive film as defined above, characterised by the steps of i) mixing a solution of said androgen in water and/or ethanol with a water-containing mixture of the carrier material; ii) spreading out as a thin layer the mixture of i); and iii) drying by removing the solvent to form said mucoadhesive film.
Patent NZ-593988-A (NZ)
Title: Apparatus and method of diagnosis of Cheyne-Stokes breathing in a person
Inventor: ARMITSTEAD JEFFREY
IPC: G06F7/20
Filed: 2005-12-21
Abstract: Disclosed is an apparatus, system, and method of diagnosis for detecting the presence of Cheyne-Stokes breathing in a person. The apparatus, system and method of diagnosis comprise the following: computer processing means for monitoring a signal indicative of respiratory flow of the person; computer processing means for deriving a jump feature from the signal, the jump feature comprising a characterization of an increase in flow at the beginning of a hyperpnoea; computer processing means for deriving a peak feature from the signal, the peak feature comprising an indication of a peak in a spectrogram of a portion of the signal; and computer processing means for detecting whether the respiratory flow of the patient includes an indication of the presence of Cheyne-Stokes breathing based on an analysis of the jump feature and the peak feature.