baber/WOPTO huggingface dataset:
Patent CA-2710966-A1 (CA)
Inventor: DELUCA HECTOR F
IPC: A61K31/593
Filed: 2008-12-24
Abstract: This invention discloses (20R)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin D  analogs, and specifically (20R)-23,23-difluoro-1.alpha.-hydroxy-2-methylene-19-nor-bishomopregnacalciferol, and pharmaceutical uses therefor. This compound exhibits pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion.  This compound also has little, if any, calcemic activity and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.
Patent CA-2711134-A1 (CA)
Inventor: ALI AMJAD
IPC: A61K31/41
Filed: 2009-01-08
Abstract: A compound having the structure (I) wherein R is an angiotensin receptor antagonist active group, Y 17 is selected from the group consisting of (II), and 2) -C(R 1 H)OC(O)X((CR 12 R 13)-(CHR  10)m-(CH2)n-Z p-(CH2)q-(CHR 11)r-(CR 16 R 17))-R 5; Z is o- or (CR 14 R 15)-; m, n, p, q, and r are independently selected from the group consisting of 0 and 1; X is O- or (CR 18 R 19)-; R is selected from the group consisting of hydrogen, C1-4 alkyl, aryl and C1-4 alkylaryl; R 5 is -O-N=N(O)-NR 3R 4; or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension.
Patent CA-2714250-A1 (CA)
Inventor: MCGUCKIN JAMES F
IPC: A61B17/03
Filed: 2010-09-07
Abstract: A device for closing an aperture in a vessel wall comprising a covering member having a longitudinal axis and positionable inside the vessel against the internal opening of the aperture and having a dimension to prevent egress of fluid through the aperture and having a first opening. A first retainer is positionable external of the vessel. A flexible connecting member operatively connects the covering member and the first retainer, wherein the first opening of the covering member is configured to restrict movement of the connecting member.
Patent CA-2715319-A1 (CA)
Inventor: LACKNER MARK
IPC: C12Q1/68
Filed: 2009-03-12
Abstract: Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM 1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.
Patent CA-2715432-A1 (CA)
Title: System and method for enhancing a decoded tonal sound signal
Inventor: VAILLANCOURT TOMMY
IPC: G10L19/12
Filed: 2009-03-05
Abstract: A system and method for enhancing a tonal sound signal decoded by a decoder of a speech-specific codec in re-sponse to a received coded bit stream, in which a spectral analyser is responsive to the decoded tonal sound signal to produce spectral parameters representative of the decoded tonal sound signal. A  quantization noise in low-energy spectral regions of the decoded tonal sound signal is reduced in response to the spectral parame-ters produced by the spectral analyser. The spectral analyser di-vides a spectrum resulting from spectral analysis into a set of criti-cal frequency bands each comprising a number of frequency bins, and the reducer of quantization noise comprises a noise attenuator that scales the spectrum of the decoded tonal sound signal per crit-ical frequency band, per frequency bin, or per both critical fre-quency band and frequency bin.
Patent CA-2717425-A1 (CA)
Title: Battery housing and cover for 3d glasses
Inventor: MACNAUGHTON BOYD
IPC: H01M50/147
Filed: 2010-10-13
Abstract: A viewing system for viewing video displays having the appearance of a three dimensional image.
Patent CA-2719703-A1 (CA)
Inventor: DANEKILDE OLE
IPC: H01Q1/22
Filed: 2008-04-16
Abstract: Communication between RFID tags and RFID reader conveyed by an inductive link comprising a first (114, 212, 324)and a second coil (118, 216, 328) interconnected by a pair of conductors (116, 326) characterised in that the first coil (114, 212, 324) is configured to interact electromagnetically with a communication unit (110, 210, 320) and the second coil (118, 216, 328) is configured to interact electromagnetically with a wireless memory unit (122, 316). The inductive link may be realised as conducting wires or as cut-outs of metal plate, and possibly employed for specifically accessing individual RFID tags by using a switching means, and employed in a system for identification and organisation of laboratory samples.
Patent CA-2720853-A1 (CA)
Inventor: HUANG ARTHUR J
IPC: C07K16/18
Filed: 2009-04-27
Abstract: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
Patent CA-2721183-A1 (CA)
Title: Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
Inventor: MANOHARAN MUTHIAH
IPC: A61K47/48
Filed: 2009-04-10
Abstract: The invention relates to compositions and methods for site-specific delivery of nucleic acids by combining them with targeting ligands and endosomolytic components.
Patent CA-2723608-A1 (CA)
Title: Iron-air accumulator with lithium mediator
Inventor: LASCAUD STEPHANE
IPC: H01M50/426
Filed: 2009-05-11
Abstract: The invention relates to a semi-accumulator that includes: (a) an electrode formed by an electron collector (3) comprising one or more transition metals from Groups 4 to 12 of the periodic table, and by an electrochemically active material (4) provided at the surface of the electron collector and in the form of a nanostructured conversion layer containing nanoparticles having a mean diameter of 1 to 1000 nm, said electrochemically active material containing at least one compound of the transition metal(s) provided in the electron collector; and (b) a continuous layer of a solid electrolyte (5) capable of conducting lithium ions, impervious to water and air and totally covering the surface of the nanostructured active material of the electrode (a). The invention also relates to an electrochemical generator comprising such a semi-accumulator as a negative electrode, preferably in the presence of an aqueous electrolyte containing LiOH.
Patent CA-2724692-A1 (CA)
Inventor: BALBO BLOCK MAIKE VIVIAN
IPC: B29C33/60
Filed: 2010-12-09
Abstract: The present invention relates to release agent compositions which contain as components: a) at least one phosphate and b) at least one compound having at least two hydroxyl groups and having a molecular weight of less than 250 g/mol, the proportion of the component a), based on the composition, being from 0.1 to 70% by weight and the proportion of component b) being from 0.5 to 90% by weight, a process for the production of composite mouldings in which these release agent compositions are used, composite mouldings obtainable in a corresponding manner and the use thereof.
Patent CA-2724987-A1 (CA)
Inventor: RAY CLIFFORD H
IPC: G01V1/24
Filed: 2009-03-19
Abstract: A self-contained, wireless seismic data acquisition unit having a cylindrically shaped case with smooth side walls along the length of the case. A retaining ring around the circumference is used to secure the cylindrical upper portion of the case to the cylindrical lower portion of the case. Interleaved fingers on the upper portion of the case and the lower portion of the case prevent the upper portion and the lower portion from rotating relative to one another.    Ruggedized external electrical contacts are physically decoupled from rigid attachment to the internal electrical components of the unit utilizing electrical pins that "float" relative to the external case and the internal circuit board on which the pins are carried.  The seismic sensors in the unit, such as geophones, and the antennae for the unit are located along the major axis of the cylindrically shaped case to improve fidelity and timing functions.
Patent CA-2725975-A1 (CA)
Inventor: JONTE PATRICK B
IPC: B05B1/22
Filed: 2010-12-20
Abstract: A proximity sensor is disclosed. The proximity sensor may be incorporated as part of a water delivery device. A holder which aligns an optical source and sensor of the proximity sensor is disclosed.
Patent CA-2726017-A1 (CA)
Title: Procede de traitement d'effluents liquides charges en hydrocarbures
Inventor: MARTIN CHRISTIAN
IPC: C02F1/24
Filed: 2008-05-28
Abstract: La présente invention concerne Procédé de traitement d'effluents liquides chargés en hydrocarbures, consistant à : acheminer les effluents dans une cuve de traitement, alimenter la cuve de traitement avec un agent sorbant réversible présentant une granulométrie déterminée; mélanger les effluents avec l'agent sorbant réversible dans la cuve de traitement pour charger ledit agent sorbant réversible en hydrocarbures contenus dans les effluents; évacuer en partie supérieure de la cuve de traitement l'agent sorbant réversible chargé en hydrocarbures; extraire de la partie inférieure de la cuve de traitement les effluents traités, et séparer les hydrocarbures de l'agent sorbant réversible chargé provenant de la cuve de traitement.
Patent CA-2727346-A1 (CA)
Title: Well jet device for logging and developing horizontal wells with abnormally low formation pressure
Inventor: KHOMYNETS ZINOVIY DMITRIEVICH
IPC: E21B47/00
Filed: 2009-07-01
Abstract: The device comprises, mounted on a flexible smooth pipe (1), a logging instrument (2), a movably arranged sealing unit (3) and a jet pump (4). The output of the diffuser (8) of the pump (4) is connected to the annular space, the nozzle (6) thereof being connected to the inner cavity of the pipe (1). A return valve (10) is arranged in a channel (9) for supplying a pumped out medium. The pipe (1) is axially movable in a tubing string (11) which is provided with a packer (12) between the pipes (11) and a casing column (13). Openings (14) are made in the wall of the pipe (1) above the instrument (2). Circulation valves (15) are arranged in the tubing string (11) above the packer (12) and a carrier ring (15) with an opening for mounting an element (3) is disposed above said circulation valves. The element (3) is in the form of a body (17) which is filled with a set of elastic space plates (18) and thrust washers (19) and with a thrust pressure element (20) situated thereabove. A support socket (21) with a thrust flange (22) made on the lower end thereof and with a movable thrust collar (23) mounted thereon is secured in the lower part of a body (17). A sealing ring (24) is placed between the thrust collar (23) and the lower part of a body (17). The invention makes it possible to increase the operational reliability and the productivity of the device during the treatment of a productive formation and a well testing.
Patent CA-2728311-A1 (CA)
Inventor: CHEN LI
IPC: C07D401/12
Filed: 2009-07-06
Abstract: The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, R1 -R3 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Patent CA-2729453-A1 (CA)
Inventor: HILDEBRAND MARTIN
IPC: C02F3/34
Filed: 2011-01-18
Abstract: Described herein is a Submerged Attached Growth Reactor (SAGR) which provides nitrification (ammonia removal) from wastewater in cold to moderate climates. The system described herein is novel in that the SAGR  reactor includes more than one influent distribution point. Specifically, in addition to the first influent distribution point at the front end of the reactor, there is provided at least one additional distribution point(s) downstream of this first distribution point for introduction of influent into the reactor. As a result of this arrangement, when a second low carbonaceous biochemical oxygen demand (CBOD), high nitrogen influent is distributed into the reactor at a location downstream of the initial influent entry point, a second (or more) population of bacteria (mainly nitrifying bacteria) is established and/or maintained in a physically discrete part of the overall treatment reactor. This second (or more) population at a discrete location within the reactor is useful in the removal of ammonia from high CBOD influent when the reactor is exposed to low temperatures.
Patent CA-2730961-A1 (CA)
Inventor: HOEVIK JON
IPC: B63B21/50
Filed: 2009-07-16
Abstract: A mooring arrangement for a semi-submersible offshore structure having an outer hull with a lower (2) and an upper (1) water line, comprises a mooring line (4) extending from a fixed point on the seabed to an attachment on the offshore structure, at least a portion of the mooring line closest to the attachment being a chain. The attachment comprises a hawse (10) and a chain stopper (22) located below the lower water line. The chain stopper (22) is located in a dry space inside the outer hull and is sealingly attached at one end to the hawse and at the opposite end to a chain pipe (9) which extends inside the hull to above the upper water line. The hawse extends outwards from the chain stopper and is sealed to an opening in the outer hull.
Patent CA-2732897-A1 (CA)
Title: Interactive rendering of physical entities
Inventor: BRUASET ARE MAGNUS
IPC: G06T17/00
Filed: 2009-07-31
Abstract: A method for generating a model of a physical entity, in particular the earth, using one or more hierarchically organised multi-resolutional data trees T, each data tree comprising a plurality of nodes Nk, each node having a grid with a fixed number of points, wherein each node can store an arbitrary number of data items, each holding scalar field values for each point in the grid, the method comprising the steps of creating a geometry using one or more data trees; and creating an associated overlay using one or more data trees, wherein at least one of the geometry and overlay comprises a formula to be applied to data within one or more data trees. This enables manipulation of the data within the data trees during rendering and increases the adaptability of the model without an increase in the required memory space. In preferred embodiments the nodes of the data trees comprise time dependent geo- references to allow the data trees to be time rotated.
Patent CA-2736439-A1 (CA)
Inventor: HAYES RICHARD ALLEN
IPC: C08F255/02
Filed: 2009-10-30
Abstract: A pipe or tube article comprising an innermost comprising a grafted polyolefin composition made from a grafted polyolefin composition is disclosed which can provide long lifetime, highly abrasion-resistant pipes for mining and other transportation uses. Methods for preparing the article and transporting abrasive materials through the article are also described.
Patent CA-2737446-A1 (CA)
Inventor: HARDY CRAIG JULIAN
IPC: A61L15/60
Filed: 2009-09-14
Abstract: The present invention relates to an absorbent wound care device comprising two or more materials which individually do not gel when exposed to a fluid but do gel when brought together and exposed to a fluid. The device is particularly intended for haemostatic use and for absorbing bodily fluids being emitted from wounds and physiological target sites.
Patent CA-2740928-A1 (CA)
Inventor: CABRI WALTER
IPC: C07C255/54
Filed: 2009-12-21
Abstract: The present invention relates to new retinoid derivatives of Formula (I), and to pharmaceutical compositions containing them for the treatment of patients affected by pathologies such as arthritic conditions, tumours, metastatic cancer, diabetic retinopathy, psoriasis, chronic inflammatory diseases or atherosclerosis.
Patent CA-2741106-A1 (CA)
Inventor: SCEKIC VLADIMIR
IPC: B66D1/22
Filed: 2011-05-24
Abstract: A hoisting device including a cable drum, a first motor, a second motor and a gear assembly is provided. The gear assembly includes a first epicyclic and a second epicyclic. The first epicyclic includes a first carrier rotationally connected to the cable drum, a first sun rotationally connected to the first motor, a first annulus, and a first planet in meshing engagement with the first sun and the first annulus. The second epicyclic includes a second carrier rotationally grounded, a second sun rotationally connected to the second motor, a second annulus connected to the first annulus, and a second planet in meshing engagement with the second sun and the second annulus.
Patent CA-2741790-A1 (CA)
Inventor: FEIBUSH PENINA
IPC: C07C227/16
Filed: 2009-10-27
Abstract: The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators.
Patent CA-2742336-A1 (CA)
Title: Fire suppression system
Inventor: SEEBALUCK DHARMENDR LEN
IPC: A62C2/00
Filed: 2011-06-07
Abstract: A fire suppression system includes a volume reduction system having a seal member. The seal member is selectively deployable between a first position and a second position to seal an opening in a confined space.
Patent CA-2745023-A1 (CA)
Inventor: VERSTEYLEN SAYANDRO
IPC: A23L3/34
Filed: 2011-06-29
Abstract: An absorbent food pad having an active agent positioned selectively in a pad architecture to provide superior performance.
Patent CA-2746248-A1 (CA)
Inventor: ZAZULA BRADLEY M
IPC: A01F25/14
Filed: 2011-07-08
Abstract: A bin lid assembly includes a lid member arranged to span across an opening in the roof of a grain storage bin. The lid member is supported by a hinge which is biased towards a closed position extending forwardly across the bin opening from an open position extending rearwardly. An operating linkage is pivotally connected to the lid member and includes a opening arm which is folded relative to the lid member from a first position extending upwardly in the closed position of the lid member to a second position extending rearwardly in the open position of the lid member to allow the lid member to be opened 180 degrees. The linkage also allows a mechanical advantage to be maintained when pulling the lid open using an actuator tether alongside the bin which is connected at an upper end to the opening arm.
Patent CA-2747699-A1 (CA)
Title: Procede de synthese d'un omega-aminoacide ou ester a partir d'un acide ou ester gras mono-insature
Inventor: DUBOIS JEAN-LUC
IPC: C07C51/353
Filed: 2010-02-05
Abstract: L'invention vise un procédé de synthèse d'acides .omega.-amino-alcanoïques ou de leurs esters à partir d'acides gras naturels insaturés transitant par un composé intermédiaire de type intermédiaire de type dinitrile mono-insaturé. Le procédé objet de l'invention est simple à mettre en et évite, par rapport aux procédés connus, d'une part les contraintes environnementales et d'autre part les handicaps économiques dus aux sous-produits des réactions.
Patent CA-2748121-A1 (CA)
Title: Peptides and compositions for prevention of cell adhesion and methods of using same
Inventor: ZLOTKIN AMIR
IPC: C07K14/435
Filed: 2009-12-28
Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of FDYDWY, SFSQNKSVHSFDYDWYNVSDQADLKN or CSFSQNKSVHSFDYDWYNVSDQADLKNC, or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.
Patent CA-2752181-A1 (CA)
Inventor: PORT MARC
IPC: A61K51/00
Filed: 2010-02-11
Abstract: The present invention relates to a method for complexation of a chelate with a radionuclide, advantageously gallium, the complexation being carried out advantageously at ambient temperature without heating, by adding the radionuclide to the chelate in a buffer solution, the buffer of this solution comprising between two and five functions for coordination with the radionuclide, each coordination function being independently chosen from a carboxylic acid function and a hydroxyl function, on the condition that the buffer comprises at least one carboxylic acid function and at most two carboxylic acid functions. It also relates to the injectable solution obtained.
Patent CA-2752820-A1 (CA)
Inventor: SELVAGANAPATHY RAVI PONNAMBALAM
IPC: C12M1/42
Filed: 2011-09-15
Abstract: A method of controlling nematode response in a microfluidic environment is provided comprising exposing the nematode to an electric field that induces a nematode response. In one embodiment, a method of sorting a group of nematodes based on a selected parameter is provided comprising the step of exposing the nematodes to an electric field that induces a differential response among the nematodes based on the selected parameter, wherein the differential response functions to separate the nematodes based on the selected parameter.  Devices useful to achieve these methods are also provided.
Patent CA-2753444-A1 (CA)
Inventor: VENKATESH GOPI
IPC: A61K9/52
Filed: 2010-02-23
Abstract: The present invention relates to pharmaceutical compositions, and methods of preparing such compositions, comprising one or more populations of controlled-release particles comprising one or more proton pump inhibitors. The present invention also relates to pharmaceutical dosage forms, including orally disintegrating tablets, tablets, capsules, and methods for their preparation.
Patent CA-2758378-A1 (CA)
Title: Therapeutic antennapedia-antibody molecules and methods of use thereof
Inventor: EPENETOS AGAMEMNON
IPC: C07K19/00
Filed: 2010-04-14
Abstract: An antibody or fragment thereof combined with Antennapedia or a fragment thereof, is an effective therapeutic agent. The invention describes the construction of antibody or antibody fragment fused or chemically conjugated with Antennapedia at its carboxyl or its amino terminus (a "cargo-carrier" construct).
Patent CA-2762079-A1 (CA)
Title: Ensemble stratifie lamine multicouche thermoplastique, et dispositif et procede de laminage
Inventor: MICHALK MANFRED
IPC: B32B37/10
Filed: 2010-03-19
Abstract: La présente invention concerne un dispositif (14) destiné au laminage d'un ensemble stratifié laminé multicouche thermoplastique en ruban (1). Ce dispositif comprend, selon l'invention, des tôles embouties pouvant être chauffées (8.1, 8.2), et des surfaces de refroidissement (10). La largeur de ces tôles embouties (8.1, 8.2) et de ces surfaces de refroidissement (10) est supérieure ou égale à la largeur de l'ensemble stratifié (1). Par rapport aux tôles embouties (8.1, 8.2), l'ensemble stratifié (1) se présente de façon que les bords des tôles embouties (20) se trouvent en milieu de grille (5.1), et que les surfaces de refroidissement soient disposées à une distance du bord suivant de tôle emboutie n'excédant pas 3 mm, en commençant dans la même grille (5). La longueur des surfaces de refroidissement (10) est supérieure ou égale à la longueur des tôles embouties (8.1, 8.2). Une tôle emboutie (8.1, 8.2) et une surface de refroidissement (10) sont chacune disposées des deux côtés de l'ensemble stratifié. Les tôles embouties (8.1, 8.2) sont fixées à des blocs de fixation pour tôle emboutie (15) prenant appui sur une première table de presse (19.1) ou pouvant être mis en mouvement par cette même table de presse. En outre, les surfaces de refroidissement (10) font parties intégrantes de blocs de refroidissement (16) prenant appui sur une seconde table de presse (19.2) ou pouvant être mis en mouvement par cette seconde table de presse. L'invention concerne également un ensemble stratifié laminé multicouche thermoplastique (1) et un procédé de laminage d'un ensemble stratifié laminé multicouche thermoplastique en ruban (1).