baber/WOPTO huggingface dataset:
Patent BG-65024-B1 (BG)
Title: Thermodynamically stable form of (r)-3-[(-4-fluorophenyl) sulphonyl]amino 1,2,3,4-tetrahydro-9h-carbazole-9-propanoic acid (ramatroban), method for the preparaton of a medical composition and usage
Inventor: GRUNENBERG ALFONS
IPC: A61P7/00
Filed: 2000-06-23
Abstract: The present invention relates to a thermodynamically stable modification of the active compound ramatroban. The thermodynamically stable form is prepared either by melting of the metastable form of subsequent recrystallization or by seeding a solution of the metastable active compound with a second crystal of the thermodynamically stable form. The thermodynamically stable active compound can be employed as an asthma agent.
Patent BG-65057-B1 (BG)
Title: Method for preparing an n-[(aliphatic or aromatic)carbonyl]-2-aminoacetamide compound and a cyclyzed compound
Inventor: HULME CHRISTOPHER
IPC: C07D205/08
Filed: 2000-08-29
Abstract: The present invention relates to a method for preparing an N-[(aliphatic or aromatic) carbonyl]-2-aminoacetamide compound of wherein Ra is Raa is hydrogen, optionally substituted aliphatic or optionally substituted aromatic; Rb is hydrogen, optionally substituted aliphatic or optionally substituted aromatic; Rca and Rcb are independently hydrogen, optionally substituted aliphatic or optionally substituted aromatic; Rd is and Rda is optionally substituted aliphatic or optionally substituted aromatic; and Raa is substituted with a primary or secondary protected amine that upon deprotection can react with the *ab or *db carbon, or at least one of Rb, Rca or Rcb where each is at least substituted with an activated carboxylic acid to form 5-7 membered cyclic ring; or Rb is substituted with a primary or secondary protected amine that upon deprotection can react with the *ab or *db carbon, or at least one of Rb, Rca or Rcb where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring; or Rca and Rcd are independently substituted with a primary or secondary protected amine that upon deprotection can react with the *ab or *db carbon, or at leastone of Raa, Rb, Rc, Rcb and Rda where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring; or Rda is substituted with a primary or secondary protected amine that upon deprotection can react with at least one of Rca and Rcb where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring; provided that when Raa issubstituted with a primary or secondary protected amine that upon deprotection can react with Rb at least substituted with an activated carboxylic acid, when Raa is other than substituted aliphatic, comprising reacting the following four components: a carbonyl compound of formula an amine compound of formula NH2Rb, an isonitrile compound of formula NCRda, and an acid compound of formula RaCO2H, t
Patent BG-65241-B1 (BG)
Title: Furostanol saponins, method for the preparation of furostannol saponins from the active substance isolated from tribulus terrestris, and application thereof
Inventor: KOSTOVA IVANKA
IPC: A61K36/185
Filed: 2001-08-07
Abstract: The invention relates to new furostanol saponins and to a method for obtaining furostanol saponins from the biologically active substance isolated through alcohol extraction from Tribulus terrestris L. According to the invention, novel, undescribed so far in the literature biologically active substances are obtained, which are contained in the known Tribulus terrestris L preparation. These compounds can be discovered and proven for the purposes of producing the preparation by an easy to understand method. Still another advantage of the invention consists in that the methods worked out allow the individual industrial obtaining of the pure compounds needed by the producers of the phytochemical preparation as standard specimen for ensuring a production meeting the modern high requirements to the quality and purity of the medicaments produced, in accordance with GMP. The invention makes it possible to standardize the preparation by one or more of its active components. Protodioscin and prototribestin are produced in a more beneficial and productive manner.
Patent BG-64347-B1 (BG)
Title: Filtering product for decontaminating radioactive wastes from nuclear power plants and method for the preparation thereof
Inventor: TSVETKOVA ANELIYA
IPC: C02F3/00
Filed: 2001-10-15
Abstract: The filtering product is used for the decontamination of liquid radioactive wastes from Nuclear Power Plants (cubic residue) to a degree of 99.5 to 99.9%. It can be subjected to cementation using industrial type cement in 1:1 ratio to the strength characteristic of structural concrete and subsequent burial in cubes. The filtering material is on mineral base and was produced by granulation to fraction of 0.5-2.5 mm chemically modified with sodium, potassium, ammonium, silver, nickel, aluminium, iron and manganese salts a heat-stabilized at 120-350 degrees C of natural aluminosilicate (clinoptilolite) containing 80-85% useful component. The different modified components have been taken in different combinations, depending on the radionuclide and chemical composition of the liquid radioactive waste.
Patent CH-699067-B1 (CH)
Inventor: GARINO GILLES
IPC: A44C5/24
Filed: 2008-07-01
Abstract: Dispositif de réglage fin de la longueur d’un bracelet (189) pourvu d’un fermoir de type déployant. Ledit fermoir de type déployant comporte au moins un couvercle d’ouverture et de fermeture (160) pourvu d’au moins un premier et un second perçages (165, 166). Ledit dispositif de réglage fin comporte un support de base (280), un dispositif de fixation (290) susceptible d’attacher une extrémité d’un brin (189) du bracelet (189) au support de base (280), et au moins un premier élément à bille susceptible d’engrener avec sa bille l’un des premier et second perçages (165, 166) pour fixer ledit support de base (280) au couvercle d’ouverture et de fermeture (160). Ledit premier perçage (165) définit une première position de réglage fin du brin de bracelet (189) et ledit second perçage (166) définit une seconde position de réglage fin du brin de bracelet (189).
Patent CU-24613-B1 (CU)
Title: Proteínas de unión a inmunoglobulinas fabs en tandem (fit-ig) biespecíficas que se unen a cmet y egfr
Inventor: WU CHENGBIN
IPC: C12P21/08
Filed: 2017-02-06
Abstract: <p>La presente invención proporciona proteínas de unión a inmunoglobulinas Fabs-en-tandem (FIT-Ig) biespecíficas, tetravalentes, que se unen a cMet y EGFR. Dichas proteínas pueden ser utilizadas en el tratamiento de diversos tipos de cáncer.</p>
Patent EP-1036697-B1 (EP)
Inventor: EHEMANN ERNST K DIPL-ING
IPC: B60N2/68
Filed: 2000-01-15
Granted: 2003-05-28
Abstract: In a passenger seat support arrangement for a people mover comprising a seat portion and a seat portion support structure including a transverse beam on which the seat portion is supported, the transverse beam has, in its top side adjacent the seat portion, at least one recess which extends into the transverse beam and has a sidewardly extending undercut with an inclined top wall having at the base of the undercut a greater distance from the top side of the transverse beam than at its entrance, and the seat portion has at least one projection extending into the recess and having a bent-over end shaped so as to be snugly received in the undercut for firmly holding the seat portion in engagement with the transverse beam.
Patent EP-1043413-B1 (EP)
Inventor: WALDENSTROEM MATS
IPC: C22C1/05
Filed: 2000-03-30
Granted: 2006-09-06
Abstract: The present invention relates to a method of making a cemented carbide with submicron WC grain size with powder metallurgical technique milling, pressing and sintering. The method consists in premixing all components except WC for >2 hours, adding the WC powder and then finally milling for about 10 hours. In this way a cemented carbide powder with acceptable low compacting pressure is obtained.
Patent EP-1055555-B1 (EP)
Inventor: BECKMANN JAN-DIRK
IPC: B60P3/22
Filed: 2000-05-18
Granted: 2004-11-10
Abstract: The silo-container with inner chamber for tippable material especially powdery goods. The silo container (100) has an auxili air circulation circuit, which sucks in air, dehumidifies and the dry air is supplied to the silo-container. The air circulation circuit is designed sealed, so that the air circulation circuit removes the suction air of the inner chamber. The air circulating circuit emanating from the inner chamber has the following: a suction line (16), a plant compressor (20 an air drier-air cooling unit (28) with an automatic dewatering (30) also an air return line (38) to the inner chamber of the silo-container (100).
Patent EP-1060969-B1 (EP)
Inventor: MUELLER-BONDER GUIDO DIPL-ING
IPC: B60L9/30
Filed: 2000-05-27
Granted: 2003-08-20
Abstract: The rail vehicle has at least one interchangable or modifiable carriage component (3), which can be fitted with components for operation via a secondary energy supply system (2), in conjunction with at least one locomotive module (4) for operation with a primary energy supply system (1).
Patent EP-1076404-B1 (EP)
Inventor: BUSCH PETER
IPC: H02M1/00
Filed: 2000-07-10
Granted: 2009-09-16
Abstract: The circuit includes an adder (A) for adding two electrical quantities (Im, Imw), one of which is a detected instantaneous current value (Im) of a selected output of the power supply. An averaging component (M) is provided for generating the respective average (Imw) of the detected instantaneous current value, using a suitable time constant. The adder is formed from two resistors. The averaging component is formed from RC elements and may include a controlled switch.
Patent EP-1064832-B1 (EP)
Inventor: MOWATT JEFFREY W
IPC: A01B71/02
Filed: 2000-06-23
Granted: 2004-04-14
Abstract: A hitch control unit 10 for use in a tractor comprises a housing 12 that defines an arcuate surface having a tangentially extending slot 14. An arm 52 extending through the slot 14 is rotatably mounted in the housing 12 and connected to a transducer to produce a signal indicative of the position of the arm 16 along the slot 14. A stop 26 movably mounted in the housing defines a reference position for the arm 52 along the slot 14, and a finger actuated wheel 24 rotatably mounted in the housing 12 allows the position of the movable stop 26 along the slot 14 to be adjusted. The wheel 24 has an internally screw threaded bore and is mounted in the housing 12 for rotation about an axis that extends parallel to the slot 14 and the adjustable stop 26 is connected to an arcuate rack 60 in screw threaded engagement with the bore in the wheel 24.  <IMAGE>
Patent EP-1045558-B1 (EP)
Inventor: BIANCHINI RONALD P JR
IPC: H04Q3/52
Filed: 2000-04-06
Granted: 2006-11-02
Abstract: A switching system. The system includes I input port mechanisms which receive packets from a communication line and have a width, where I is greater than or equal to 1 and is an integer. The system includes O output port mechanisms which send packets to a communication line and have a width, where O is greater than or equal to 1 and is an integer. The system includes a carrier mechanism along which packets travel. The carrier mechanism has a width wider than the width of the input and output port mechanisms. The carrier mechanism is connected to each input port mechanism and each output port mechanism. The system includes a memory mechanism in which packets are stored. The memory mechanism is connected to the carrier mechanism. The system includes a mechanism for providing packets to the memory mechanism though the carrier mechanism from the input port mechanisms. The providing mechanism is able to transfer packets or portions of packets whose total width equals the width of the carrier mechanism in each transfer cycle to the memory mechanism. A switching system for packets. A method for switching packets. The method includes the steps of receiving a first packet and at least a second packet at a switch mechanism. The method includes the steps of transferring data of the first packet and the second packet to a memory mechanism via time division multiplexing of a bus having a width so data from the packets fills a predetermined portion of the width of the bus. The bus width is not necessarily equal to the packet size. <IMAGE>
Patent EP-1132012-B1 (EP)
Inventor: CASELLI ORESTE
IPC: A23L3/32
Filed: 2000-03-03
Granted: 2003-01-02
Abstract: This invention relates to a method and an apparatus for sanitizing packaged food products by means of air ions in order to extend their shelf life and preservability at retail outlets. According to the invention, the packaged food products are held within an electric field, being generated between two electrodes, by supplying the electrodes with a periodic voltage, the strength of said electric field being controlled between a minimum value, sufficient to generate the air ions, and a maximum value which is below that needed to strike an electric arc. Advantageously, the electric field is established between a pair of plate-like electrodes facing each other, and at least one of the electrodes is coated with an insulating material. <IMAGE>
Patent EP-1151918-B1 (EP)
Inventor: PETRETTO GESUINO
IPC: B64C31/028
Filed: 2000-05-05
Granted: 2003-11-19
Abstract: A hang glider (1) comprises a bearing tubular structure made of a longitudinal crossbar (4), a lower control trapeze (2) an upper vertical turret (6) and two wing spars (8), and a variable dihedral angle wing (10), which has its ends secured to the ends of the two spars and is secured to said lower control trapeze (2) through a plurality of cords (22a-28a,22b-28b) of which the lengths can be varied to lift or lower the wing, thereby varying the hang glider lift and speed during flight. <IMAGE>
Patent EP-1166122-B1 (EP)
Inventor: KAEKONEN SANNA-MARIA
IPC: G01N33/68
Filed: 2000-03-20
Granted: 2009-02-11
Abstract: This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.
Patent EP-1170986-B1 (EP)
Inventor: FAN SHIHE
IPC: A01H4/00
Filed: 2000-04-14
Granted: 2004-09-08
Abstract: A process of nutripriming plant somatic embryos prior to sowing, comprising contacting an imbibed plant somatic embryo with a solution containing one or more dissolved nutrients, preferably including sucrose as one of the nutrients. The invention includes germinated embryos produced by the process, and a method of producing seedlings or full-grown plants incorporating the nutripriming step. The method preferably makes use of a growth medium containing the nutrient or nutrients used in the nutripriming step.
Patent EP-1187556-B1 (EP)
Inventor: MOSER WALTER
IPC: A61B17/15
Filed: 2000-06-02
Granted: 2006-03-29
Abstract: The invention relates to a device for tensioning ligaments of non-spheroid joints in human or animal bodies, comprising A) a plate-shaped base body (2) with a right and a left blade (3; 4) whose contact surfaces (16) can be brought into contact with the surface of a first bone which is located on the side of the joint and lies adjacent to a joint (10) and a right and a left handle (6; 7); B) a right and a left tensioning lever (8; 9) whose contact surfaces (15) can be brought into contact with the surface of a second bone which is located on the side of the joint and lies adjacent to the joint (10); C) a right and a left operating lever (11; 12), each of which can be actuated simultaneously with the corresponding handle (6; 7) whilst holding the device, using the same hand; D) a right and a left parallel displacement device (13; 14) which can be used during a displacement of the operating levers (11; 12) to displace the contact surfaces (15) of the tensioning levers (6; 7) independently of one another in a perpendicular direction to the plane (5); E) the parallel displacement devices (13; 14) are quadruple-joint lever mechanisms, and F) a force indicator (17) displays the expansion force in newtons.
Patent EP-1183690-B1 (EP)
Inventor: BALDISCHWEILER MICHAEL
IPC: G06F21/75
Filed: 2000-05-11
Granted: 2002-12-04
Abstract: A memory array includes a plurality of storage cells (10) and a selection device (14) which selects a storage cell (10) for physical access due to a logical address (23) supplied via an address bus (20). The selection device (14) includes a scrambling device (15) which allocates a storage cell (10) in the memory array in predictable fashion by scrambling to a logical address (23) transmitted to one of the selection devices (14), the cell then being physically accessed.
Patent EP-1233852-B1 (EP)
Inventor: HULL RAYMOND J JR
IPC: A61F13/20
Filed: 2000-05-11
Granted: 2004-11-03
Abstract: A method for separating a supply of material (10) into distinct sections of material (11), while controlling the position and orientation of these distinct sections during further manipulation in a continuous process is disclosed. The method includes forming a line of weakness comprising perforations (50) and scores (51) extending substantially from the first edge to the second edge and applying a force substantially parallel to the length of the web (10) sufficient to separate an individual sheet (11) from the web at the line of weakness.
Patent EP-1189553-B1 (EP)
Inventor: STRATFORD PETER WILLIAM
IPC: A61F2/91
Filed: 2000-06-26
Granted: 2004-03-31
Abstract: The present invention relates to a balloon expandable stent mounted on a balloon catheter, the entire assembly being overcoated with a coherent polymer coating, which is preferably substantially continuous over the circumference and, more preferably, axial length of the stem on the balloon. The polymer coating improves retention of the stent on the balloon during delivery and does not adversely effect the deployment characteristics, nor the balloon failure characteristics. The product is made by mounting the stent on the balloon and coating the assembly with a liquid coating composition containing a suitable polymer followed by curing of the coating. The polymer is biocompatible and preferably crosslinkable in the coating composition, and crosslinked in the final product. A suitable polymer is formed from monomers including a zwitterionic, preferably a phosphoryl choline, group, and monomers including a trialkoxysilyl group. Preferably the coated product is contacted with ethylene oxide to provide simultaneous sterilization and additional curing.
Patent EP-1191925-B1 (EP)
Inventor: MAZER TERRY B
IPC: A61K9/20
Filed: 2000-06-28
Granted: 2005-09-07
Abstract: Dosage form unit is provided to deliver one or more beneficial agents into a fluid, such as liquid enteral nutritional product. The dosage form unit includes a core containing at least one beneficial agent, preferably a marker dye, which is dispersible in the fluid. The core also contains a compatible binding agent to bind the beneficial agent together. Additional components of the core may include a plasticizer, a standard flow agent, a lubricant, additional tableting aids and at least one hydrophilic agent. A latex coating encases the core. The latex coating includes a mixture containing a substantially hydrophobic base material, preferably formed from an emulsion of cellulose acetate microspheres, which is capable of defining a matrix-type membrane, and at least one hydrophilic component being dispersible in the fluid. A dispersible beneficial agent is preferred as one of the hydrophilic components of the latex coating to allow immediate release of the beneficial agent therefrom. A method of making the dosage form unit also is provided.
Patent EP-1194139-B1 (EP)
Inventor: SUNVOLD GREGORY DEAN
IPC: A23L33/155
Filed: 2000-07-06
Granted: 2008-02-27
Abstract: A composition and method is provided for promoting weight loss in a mammal by feeding effective amounts of at least three nutrients selected from L-carnitine, chromium, Vitamin A, and a source of carbohydrates selected from a low glycemic index grain. The composition preferably includes all four nutrients and may be fed in an amount of 1.0 to 10.0 mg of L-carnitine per kilogram of body weight per day, from about 5.0 to about 15.0 micrograms of chromium per kilogram of body weight per day, and from about 1.0 to 3.0 grams of starch per kilogram of body weight per day.
Patent EP-1200672-B1 (EP)
Inventor: QUIGLEY SCOTT
IPC: D03D1/00
Filed: 2000-07-07
Granted: 2004-10-13
Abstract: A seamed endless papermaking fabric for use with papermaking machines. The fabric includes a plurality of CMD (cross machine direction) yarns intermeshing with a plurality MD (machine direction yarns) in a selected intermeshing pattern forming a contact surface and a support surface. The MD yarns, which are arranged to extend beyond the endmost of the CMD yarns at the opposed first and second ends of the fabric, form a plurality of spaced seaming loops across the fabric. These loops are adapted to interleaf and receive a pintle which forms the seam forming the fabric endless. A first pair of additional yarns are intermeshed in a first intermeshing pattern repeat with the MD yarns outwardly of the endmost of the CMD yarns at one of the opposed ends and a second pair of additional yarns are intermeshed in a second intermeshing pattern repeat with the MD yarns outwardly of the endmost of the CMD yarns at the other of the opposed ends. These first and second pairs of additional yarns separate the endmost CMD yarns from the pintle. The additional yarns are multi-filament yarns while the MD yarns are monofilament yarns.
Patent EP-1210319-B1 (EP)
Inventor: ROESLER RICHARD R
IPC: C07C229/24
Filed: 2000-07-21
Granted: 2003-11-05
Abstract: A method for making a polyaspartic ester mixture <i>in-situ</i> comprising the sequential steps of (a) reacting a cyclic amine with an excess amount of an ester of fumaric or maleic acid to form a mixture containing first polyaspartic ester component and excess unreacted ester of fumaric or maleic acid, and (b) adding an acyclic amine to the mixture resulting from step (a) and reacting the acyclic amine with the excess ester of fumaric or maleic acid to form a second polyaspartic ester component.
Patent EP-1236038-B1 (EP)
Inventor: MAYER FELIX
IPC: G01N27/22
Filed: 2000-09-06
Granted: 2005-11-23
Abstract: A sensor, in particular a humidity sensor, comprises a measuring layer (4), the dielectric properties of which depend on a parameter to be measured, e.g. of the humidity of the environmental air. Electrodes (2, 3) are arranged on a substrate (1) side by side for capacitively measuring the measuring layer (1). A protective layer (8) of a non-oxidizing material, in particular a layer of silicon oxide or gold, is arranged between the electrodes (2, 3) and the measuring layer (4). This layer prevents an oxidation of the electrodes (2, 3) and increases the live time and reliability of the sensor.