baber/WOPTO huggingface dataset:
Patent WO-2020117288-A1 (WO)
Title: Deuterated agonists and methods of use
Inventor: MCKINNEY JEFFREY
IPC: A61K31/265
Filed: 2019-11-15
Abstract: The present invention is generally directed to deuterated agonists and their methods of use. It is more specifically directed to deuterated alpha-7 nicotinic receptor agonists and their methods of use. In one aspect, the present invention involves compounds of the structure 1-34 as shown in FIGs. 1-4. In another aspect, the present invention involves the treatment of a disorder with a compound of the structure 1-34 as shown in FIGs. 1-4.
Patent WO-2019160666-A1 (WO)
Title: Trace recording by logging influxes to an upper-layer shared cache, plus cache coherence protocol transitions among lower-layer caches
Inventor: MOLA JORDI
IPC: G06F11/36
Filed: 2019-01-25
Abstract: Trace recording based on data influxes to an outer-level cache and cache coherence protocol (CCP) transitions between inner caches. Example computing device(s) include a plurality of processing units, a plurality of (N-1)-level caches, and an N-level cache that is associated with two or more of the (N-1)-level caches and that is a backing store for the two or more (N-1)-level caches. Based at least on detecting influx(es) of data to a location in the N-level cache during execution across the processing units, the computing device(s) causes the influx(es) of data to be logged. The computing device(s) also causes one or more (N-1)-level CCP transitions between the two or more (N-1)-level caches to be logged. The (N-1)-level CCP transitions result from the location being accessed by two or more of the processing units.
Patent WO-2019169276-A1 (WO)
Inventor: STORELLI CLAUDIO
IPC: A41C3/02
Filed: 2019-03-01
Abstract: An adjustable athletic bra that provides support laterally (side to side), vertically (up and down), and in and out to provide stability in multiple directions.
Patent WO-2019173320-A1 (WO)
Title: Web material application systems and methods
Inventor: NASH JORGE A
IPC: B65H39/06
Filed: 2019-03-05
Abstract: A system (10) for cutting a web material (11) and applying the web material (11) on a substrate (13) comprises a feed roll (16; 35) configured to advance the web material (11). The system (10) includes an anvil roll (18) configured to receive the web material (11) from the feed roll (16; 35) and provide a section (12) of web material (11) having a defined length. The system (10) includes a cutting element (20) configured to cut the web material (11) to form the section (12) of web material (11). The anvil roll (18) is configured such that the anvil roll (18) surface advances at an anvil roll surface speed. The feed roll (16; 35) is configured to rotate at a first feed roll surface speed that is slower than the anvil roll surface speed and a second feed roll surface speed that is substantially the same as the anvil roll surface speed when the cutting element (20) cuts the web material (11).
Patent WO-2019182776-A1 (WO)
Inventor: BAREL ELIYAHU
IPC: G06F3/02
Filed: 2019-03-11
Abstract: A keyboard has a keypad layer of resiliently depressible keypads. The keyboard has a skin of dielectric material, covering a base of the keyboard. The skin contacts a capacitive touchscreen in use, and an actuating layer is on a face of the skin of dielectric material away from the base. The actuating layer comprises a plurality of conductive regions, one per keypad. A grounding layer is between the actuating layer and the keypad layer and spaced from the actuating layer during a rest state of the keyboard. Upon depression of a keypad, the keypad presses a region of the grounding layer under the keypad towards a region of the actuating layer such that the region of the actuating layer becomes grounded and causes a change in capacitance detectable by the capacitive touchscreen.
Patent WO-2019182850-A1 (WO)
Inventor: TEEGAVARAPU SUDHAKAR
IPC: B21C47/26
Filed: 2019-03-14
Abstract: An automated trimming system is provided that includes a vision system identifying the number of rings positioned within a coil and sheared positions where the rings need to be cut. One or more trimming mechanisms receive the sheared positions and proceed to cut the rings at the sheared positions. A hook arrangement interfaces with the coil for transferring the coil to a trimming area. Moreover, an automated trimming system is provided that includes a coil having a plurality of rings. One or more trimming mechanisms select a number of rings from the coil and proceed to form a sample of desired length, by cutting a portion of the rings. A receiver unit receives the sample from the one or more trimming mechanisms to evaluate the quality of the sample.
Patent WO-2019182908-A1 (WO)
Inventor: HARTMAN STEVEN
IPC: A61K31/137
Filed: 2019-03-15
Abstract: Provided herein are epinephrine spray formulations. Also provided herein are methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatment.
Patent WO-2019199928-A1 (WO)
Title: Multi-layer extruded uppers for articles of footwear and other foot-receiving devices
Inventor: BRAITHWAITE NATHAN L
IPC: A43B23/02
Filed: 2019-04-10
Abstract: Upper components (1210, 3002b, 2002, 3002) for footwear (2000, 3000) include: (a) a first layer (300, 350, 400, 500, 600, 700, 800, 900) including a first filament including first plural, non-intersecting, spaced apart path segments (100a-100e) (wherein the first filament may have a width dimension of less than 3 mm wide (and in some examples, less than 2 mm wide, less than 1.5 mm wide, less than 1 mm wide, or even less than 0.75 mm wide)); and (b) a second layer (300, 350, 400, 500, 600, 700, 800, 900) including a second filament including second plural, non-intersecting, spaced apart path segments (100a-100e) (wherein the second filament may have a width dimension of less than 3 mm wide (and in some examples, less than 2 mm wide, less than 1.5 mm wide, less than 1 mm wide, or even less than 0.75 mm wide)), wherein the second layer is fused to the first layer at locations where the second layer contacts the first layer. Additional layers of material, including additional layers with filament, may be included in the upper. The filament material in the different layers may be the same or different from one another (e.g., a thermoplastic material, a thermoplastic polyurethane material, a hydrophobic material, a water-repelling material, a non-water absorbing material, etc.).
Patent WO-2019245640-A1 (WO)
Inventor: POMAHAC BOHDAN
IPC: A01N1/02
Filed: 2019-04-17
Abstract: Systems and methods to perfuse isolated tissue are provided to avoid ischemia-related tissue damage over an extended perfusion time is provided. A system can comprise a reservoir sized and dimensioned to contain a perfusate. A perfusion supply line can comprise a pump, a cooling system, an oxygenator, and at least one filter. The perfusion supply line can be in fluid communication with the reservoir to draw the perfusate from the reservoir and cool and oxygenate the perfusate. The system can also include an arterial line in fluid communication with the perfusion supply line to direct perfusate from the reservoir to the isolated tissue. A venous outflow can be in fluid communication with the isolated tissue to remove the perfusate from the isolated tissue. A perfusion return line can be in fluid communication with the venous outflow to return the perfusate from the isolated tissue to the reservoir.
Patent WO-2019210034-A1 (WO)
Inventor: WALLECHA ANU
IPC: G01N33/50
Filed: 2019-04-25
Abstract: L'invention concerne des procédés et des compositions pour évaluer la présentation d'antigène et la puissance d'agents immunothérapeutiques à base de  Listeria  dans l'induction d'une réponse immunitaire.
Patent WO-2019213442-A1 (WO)
Title: MULTISPECIFIC BINDERS OF TGFβ-SUPERFAMILY LIGANDS AND USES THEREOF
Inventor: KUMAR RAVINDRA
IPC: C07K16/22
Filed: 2019-05-02
Abstract: In certain aspects, the disclosure provides multispecific binders (e.g., ΑctRΙΙΑ:ΤβRII heteromultimers comprising an ActRlIA polypeptide and a TfiRU polypeptide). The disclosure further provides that such multispecific binders (e.g., ΑctRΙΙΑ:ΤβRII heteromultimer) may be used to treat various disorders or conditions.
Patent WO-2019221976-A1 (WO)
Title: System and method of loading and replication of sub-vector values
Inventor: MAHURIN ERIC WAYNE
IPC: G06F9/30
Filed: 2019-05-07
Abstract: A processor includes a vector register configured to load data responsive to a special purpose load instruction. The processor also includes circuitry configured to replicate a selected sub-vector value from the vector register.
Patent WO-2019236273-A1 (WO)
Title: Fabrication of electrodes for memory cells
Inventor: ZHENG PENGYUAN
IPC: H01L21/304
Filed: 2019-05-20
Abstract: Methods, systems, and devices for fabrication of memory cells are described. An electrode layer may have an initial thickness variation after being formed. The electrode layer may be smoothened prior to forming additional layers of a memory cell, thus decreasing the thickness variation. The subsequent layer fabricated may have a thickness variation that may be dependent on the thickness variation of the electrode layer. By decreasing the thickness variation of the electrode layer prior to forming the subsequent layer, the subsequent layer may also have a decreased thickness variation. The decreased thickness variation of the subsequent layer may impact the electrical behavior of memory cells formed from the subsequent layer. In some cases, the decreased thickness variation of the subsequent layer may allow for more predictable voltage thresholds for such memory cells, thus increasing the read windows for the memory cells.
Patent WO-2019227047-A1 (WO)
Inventor: HART STEPHEN
IPC: G09G3/36
Filed: 2019-05-24
Abstract: L'invention concerne des systèmes et des procédés d'amélioration de caractéristiques de fonctionnement d'écrans tels que des écrans à cristaux liquides sur silicium.
Patent WO-2019241051-A1 (WO)
Inventor: HOAN ANDREW
IPC: A61B5/15
Filed: 2019-06-07
Abstract: L'invention concerne un système de tubulure destiné à être utilisé dans un système de surveillance de la pression artérielle-prélèvement sanguin (100). Le système de surveillance de la pression artérielle-prélèvement sanguin peut comprendre une soupape de commande (132), un réservoir (130) avec un piston (164), un site d'échantillonnage (161), et un transducteur de pression artérielle (138) pour mesurer la pression artérielle d'un patient (110). Le système de tubulure peut comprendre : une pluralité de sections de tubulure flexible (125) et une pluralité de sections de tubulure rigide (123). La pluralité de sections de tubulure rigide et de sections de tubulure flexible peuvent être reliées les unes aux autres entre le patient et le transducteur de pression artérielle pour la mesure de pression artérielle du patient.
Patent WO-2019241522-A1 (WO)
Title: Dual lumen cannula with flexible distal end
Inventor: KELLY PATRICK
IPC: A61B17/34
Filed: 2019-06-13
Abstract: A dual lumen coaxial cannula assembly includes a first infusion tube having a first elongate body defining a first lumen therethrough, the first infusion tube having a proximal end, a distal end, and a sidewall extending circumferentially therebetween. A second drainage tube is co-axially aligned with the first infusion tube and has a second elongate body with a second lumen defined by a space between the first infusion tube and the second drainage tube. The second drainage tube has a proximal end, a distal end, and a sidewall extending circumferentially therebetween. A connector is attached to the proximal end of the first infusion tube and the proximal end on the second drainage tube. The cannula assembly further includes a distal tip connected to the distal end of the first elongate body and made of a material having a lower hardness than a hardness of the first elongate body.
Patent WO-2020139419-A1 (WO)
Title: Ensemble roue de charge pour empêcher un mouvement axial et rotatif d'un essieu
Inventor: REGES CLINTON
IPC: B66F9/075
Filed: 2019-06-27
Abstract: La présente invention concerne un ensemble roue de charge (40, 60) qui comporte : un élément cadre (46, 66) ; une plaque latérale (42, 62) couplée à l'élément cadre (46. 66) ; un essieu (50. 70) s'étendant entre l'élément cadre et la plaque latérale ; et un élément de retenue (52, 72) couplé par un élément de fixation (54, 74) à l'élément cadre (46. 66) ou à la plaque latérale (42, 62). L'élément de retenue est couplé à une des deux extrémités de l'essieu pour empêcher un mouvement rotatif et axial de l'essieu par rapport à l'élément cadre et à la plaque latérale.
Patent WO-2020010003-A1 (WO)
Title: AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS
Inventor: DOUTY BRENT
IPC: C07D405/12
Filed: 2019-07-01
Abstract: This application relates to compounds of Formula (I) or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Patent WO-2020010340-A1 (WO)
Title: Method and system for estimating accrued, equitably allocated distribution income from a security
Inventor: BOYDELL DAVID
IPC: G06Q40/06
Filed: 2019-07-05
Abstract: A method includes: obtaining an estimate of a total distribution to be issued by the security issuer at an end of a current payment period comprising a plurality of intervals; receiving data regarding one or more of a position of an investor in the security at an end of an interval and a length of the interval, the investor owning the security at the end of at least one of the intervals; computing, using the data, an estimate of the accrued, equitably allocated distribution income payable to the investor from the security, the distribution income equitably allocating a portion of the total distribution to the investor who owns the security at the end of at least one of the intervals; and transmitting the computed estimate of the accrued, equitably allocated distribution income to the investor.
Patent WO-2020028131-A1 (WO)
Title: Adjustable lens accessory and method of use
Inventor: NOTTAGE SANTANA
IPC: G02B25/00
Filed: 2019-07-25
Abstract: An accessory for use with a phone or tablet computer. The accessory connects to the phone, either by enveloping the phone with a case-like element or clipping to the side of the phone with a clip. A hinged lens covers at least a portion of the screen and pivotally connects to the connection portion. This lens can be tilted up from the screen to increase the effective prescription of the lens, enlarging the text and images on the screen of the phone, or can be tilted back down towards the screen to reduce the effect.
Patent WO-2020023955-A1 (WO)
Inventor: PAN SHU
IPC: B01D53/22
Filed: 2019-07-29
Abstract: Une estimation récursive bayésienne est utilisée pour analyser des paramètres de performance d'un système de séparation par membrane sur la base de données opérationnelles historiques d'un système par membrane. L'estimation bayésienne considère des données historiques sur des intervalles de temps antérieurs pour prédire des performances futures de séparation par membrane pour éviter un temps d'arrêt inattendu et une maintenance non anticipée. Un ensemble de variables d'état utilisées pour modéliser les performances est utilisé avec un modèle de dégradation pour anticiper les changements de performances et la maintenance sur la base de propriétés mesurées de perméat, de non-perméat et de flux d'alimentation.
Patent WO-2020033391-A1 (WO)
Title: System and method for selecting artificially fertilized embryos
Inventor: ZANINOVIC NIKICA
IPC: G16H50/30
Filed: 2019-08-06
Abstract: A method for classifying human blastocysts includes obtaining images of a set of artificially fertilized (AF) embryos incubating in an incubator. A morphological quality of the AF embryos is determined based on a classification of the images by a convolutional neural network trained using images of pre-classified embryos. Each of the AF embryos is graded based on the morphological quality. A probability that a given graded AF embryo will result in a successful pregnancy after the given AF embryo is implanted in a gestating female is computed for each of the AF embryos from the set based on a grade of the given AF embryo and clinical parameters associated with the gestating female. One or more graded AF embryos to be recommended to be implanted in the gestating female from the set are selected based on the probability of successful pregnancy. An identity of each of the selected graded AF embryos and a number of the selected graded AF embryos to be potentially implanted in the gestating female is then output based on an outcome desired by the gestating female following implantation.
Patent WO-2020061247-A1 (WO)
Inventor: KWON OHYUN
IPC: A61K45/06
Filed: 2019-09-19
Abstract: R-aplexone, methods of preparing R- aplexone, or aplexone substantially free of its S- stereoisomer are disclosed. Methods of using R-aplexone or a pharmaceutically acceptable salt or solvate thereof to treat and/or prevent disease are disclosed. Methods of preparing 6- substituted tetrahydropyridine motifs with high enantiomeric excess are also disclosed.
Patent WO-2021054976-A1 (WO)
Inventor: HENRY SHAUN PATRICK
IPC: B31D5/04
Filed: 2019-09-20
Abstract: L'invention concerne, selon des exemples, la génération de marques de modification de supports sur la base d'un contenu d'image. Dans certains exemples, des marques de modification pour convertir des supports bidimensionnels (2D) en une forme tridimensionnelle (3D) sont générées sur la base du traitement d'image d'une image. Dans certains exemples, les marques de modification sont appliquées aux supports 2D.
Patent WO-2020076609-A1 (WO)
Inventor: CARLSSON JONAS P
IPC: A61F5/445
Filed: 2019-10-03
Abstract: An ostomy appliance system includes an ostomy appliance having a stoma opening and a first electrical interface, and at least one thermal sensor configured to detect at least one thermal property, such as temperature, at the ostomy appliance, the at least one temperature sensor connected to the first electrical interface with electrical circuitry. A wearable device may be removably connected to the ostomy appliance and operably connected to the at least one thermal sensor. The wearable device includes a housing, a second electrical interface configured for electrical connection to the first electrical interface, a power supply and a controller operably connected to the power supply. The controller is configured to determine a condition of the ostomy appliance based on the at least one thermal property detected at the at least one thermal sensor. The wearable device may also include a wireless transceiver configured to communicate with a personal communication device.
Patent WO-2020077252-A1 (WO)
Inventor: TILLERY STEPHEN
IPC: E04H15/22
Filed: 2019-10-11
Abstract: A portable shelter for an aircraft having an exterior contoured form includes a flexible enclosure configured to substantially enclose the aircraft within an interior of the flexible enclosure; an air maintenance unit in fluid communication with the interior of the flexible enclosure; wherein the air maintenance unit further comprises a blower and a temperature control unit in fluid communication with the blower; and wherein the air maintenance unit is configured to provide conditioned air to the interior of the flexible enclosure. An associated method for sheltering an aircraft includes the steps of providing a portable shelter that includes a flexible enclosure configured to substantially enclose the aircraft within an interior of the flexible enclosure; an air maintenance unit; wherein the air maintenance unit further comprises a blower and a temperature control unit in fluid communication with the blower; placing the flexible enclosure around the aircraft; closing the flexible enclosure around the aircraft; connecting the air maintenance unit with the interior of the flexible enclosure; and operating the temperature control unit to produce conditioned air and the blower to force the conditioned air into the interior of the flexible enclosure.
Patent WO-2020086636-A1 (WO)
Title: Smart optical cable positioning/location using optical fiber sensing
Inventor: HUANG MING-FANG
IPC: H04B10/25
Filed: 2019-10-23
Abstract: Aspects of the present disclosure describe systems, methods and structures for determining any location on a deployed fiber cable from an optical time domain reflectometry (OTDR) curve using a movable mechanical vibration source to stimulate tiny vibration of fiber in deployed fiber cable along the cable route and a fiber sensing system at a central office to detect the vibration(s). Latitude and longitude of the location(s) of the vibration source is measured with a GPS device and a dynamic-OTDR distance is measured at central office (CO) simultaneously. The collected GPS location data and corresponding dynamic-OTDR distance data are paired and saved into a database. This saved data may be processed to graphically overlie a map thereby providing exact cable location on the map thereby providing carriers/service providers the ability to improve fiber fault location on a deployed fiber cable much faster and more accurately than presently possible using methods available in the art.
Patent WO-2020087047-A1 (WO)
Inventor: NOBLES ANTHONY
IPC: A61M25/00
Filed: 2019-10-25
Abstract: A catheter assembly comprises a transparent hub and a transparent catheter coupled to the transparent hub at a proximal end. The present inventive concept further contemplates that the transparent hub can further comprise components, including but not limited to, a valve, a valve housing, a catheter securing mechanism, a hub body. The present inventive concept further contemplates a catheter assembly comprising one or more transparent components, such that the catheter assembly reveals the contents therein to a user.
Patent WO-2021086343-A1 (WO)
Title: Apparatus having valves actuated by magnets
Inventor: WILLIAMS KENNETH
IPC: B41J2/175
Filed: 2019-10-30
Abstract: In some examples, an apparatus can include a plunger comprising a cavity, a bezel comprising an aperture having a particular shape, a magnet located in the cavity of the plunger, and a magnetically actuated valve connected to the bezel, where in response to the plunger being moved by a key having a shape corresponding to the particular shape of the aperture of the bezel, the magnet is to cause the magnetically actuated valve to actuate.
Patent WO-2020092711-A1 (WO)
Inventor: TAYLOR SCOTT D
IPC: B60W30/00
Filed: 2019-10-31
Abstract: A helmet (20) for communicating with a vehicle function controller (16) and method for operating the same has a first memory (512), a first transmitter (532), a first receiver (530) and a first controller (510) in communication with the first memory (512), the first transmitter (532) and the first receiver (530). The first receiver (530) receives a plurality of vehicle (10) function settings. The first memory (512) stores the vehicle (10) function settings within a memory (512) of the helmet (20). The first transmitter (532) communicates the vehicle (10) function settings from the first memory (512) to the vehicle function controller (16). A system including a helmet (20) and a vehicle (10) is also configured to enable the vehicle to start in response to an identifier communicated by the helmet (20) to a vehicle controller (610).