baber/WOPTO huggingface dataset:
Patent NZ-521442-A (NZ)
Title: Method for down-regulating amyloid deposits by enabling the production of antibodies against the relevant protein or components thereof
Inventor: JENSEN MARTIN ROLAND
IPC: A61K35/76
Filed: 2001-02-19
Abstract: Disclosed  are  novel methods for  combating  diseases characterised  by  deposition  of  amyloid.    The   methods generally   rely   on  immunisation  against   amyloidogenic proteins  (proteins  contributing to formation  of  amyloid) such  as  beta amyloid (Abeta).  Immunisation is  preferably effected   by  administration  of  analogues  of  autologous amyloidogenic polypeptides, the analogues being  capable  of inducing   antibody   production  against   the   autologous amyloidogenic  polypeptides.  Especially  preferred,  as  an immunogen  is autologous Abeta, which has been  modified  by introduction  of one single or a few foreign, immunodominant and   promiscuous   T-cell  epitopes   while   substantially preserving  the majority of Abeta 's B-cell epitopes.   Also disclosed    are    nucleic   acid    vaccination    against amyloidogenic  polypeptides  and  vaccination   using   live vaccines  as  well  as  methods and  means  useful  for  the vaccination.   Such  methods and means include  methods  for identification  of  useful  immunogenic  analogues  of   the amyloidgonic  proteins,  methods  for  the  preparation   of analogues  and  pharmaceutical  formulations,  as  well   as nucleic   acid   fragments,  vectors,   transformed   cells, polypeptides and pharmaceutical formulations. The figure  is a  schematic depiction of Autovac variants derived from  the amyloid  precursor  protein with the purpose  of  generating antibody  responses  against the A, protein  Ass-43  (or  C- 100).   The  APP is shown schematically at the  top  of  the figure and the remaining schematic constructs show that  the model  epitopes P2 and P30 are substituted or inserted  into various  truncations  of  APP.  In  the  figure,  the  black pattern  indicates the APP signal sequence,  two-way  cross- hatching  is  the extracellular part of APP;  dark  vertical hatching  is the transmembrane domain of APP; light vertical hatching  is the intracellular domain of APP, coarse  cross- hatching  indicates the P30 epitope, and fine cross-hatching indicates  the  P2  epitope.  The full  line  box  indicates "Abeta-42/43" and the full-line box and the dotted line  box together indicate C-100."Abeta".
Patent NZ-523680-A (NZ)
Title: Pharmaceutical compositions having a solid amorphous dispersion of cholesteryl ester transfer protein inhibitors
Inventor: CURATOLO WILLIAM JOHN
IPC: B29B9/00
Filed: 2001-07-31
Abstract: Cholesteryl ester transfer protein (CETP) inhibitors, such as those of Formula I; pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein (HDL)-cholesterol and to lower certain other plasma lipid levels, such as low density lipoprotein (LDL)-cholesterol and triglycerides; and their use in the manufacture of a medicament to treat diseases which are affected by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis, peripheral vascular disease, dyslipidemia, hyperbetalipoproteinemia, hypoalphalipoproteinemia, hypercholesterolemia, cardiovascular disorders, angina, ischemia, cardiac ischemia, stroke, myocardial infarction, reperfusion injury, angioplastic restenosis, hypertension, vascular complications of diabetes, obesity or endotoxemia in a mammals.
Patent NZ-527393-A (NZ)
Title: Crystal forms of pyrimidine nucleoside derivative
Inventor: TAKITA TAKASHI
IPC: A61P35/00
Filed: 2002-02-06
Abstract: Disclosed are crystalline forms of the compound 2'-cyano-2'-deoxy-N4-palmitoyl-1-â-D-arabinofuranosylcytosine of formula (I). The crystalline forms demonstrate improved stability over the amorphous form. The crystalline forms are used in the manufacture of medicaments for the treatment or prevention of tumours.
Patent NZ-528694-A (NZ)
Title: Novel PRO531 polypeptides and nucleic acids encoding same, with homology to protocadherin
Inventor: WOOD WILLIAM I
IPC: C12N15/12
Filed: 1999-03-08
Abstract: An isolated nucleic acid having at least 80% sequence identity to a nucleotide sequence that encodes a polypeptide designated PRO531 comprising the amino acid sequence SEQ ID NO:405. Preferably the nucleic acid comprises the sequence of SEQ ID NO:404 or is that deposited under accession number ATCC 209702. Vectors, isolated host cells, processes for preparing the polypeptide and antibodies are also described. (62) Divided out of 507435
Patent NZ-529053-A (NZ)
Title: A drive assembly for a fluid dispenser
Inventor: PARKER ROSS
IPC: A61D1/02
Filed: 2003-10-20
Abstract: The present invention relates to a drive assembly for a fluid dispenser where this fluid dispenser includes a chamber in communication with a fluid source. The dispenser also includes a piston moveable within the chamber to dispense fluid from and to draw fluid into the chamber. The drive assembly provided includes a drive shaft linked to the dispenser piston where movement of the drive shaft causes movement of the pistons. The drive assembly also includes an actuation element operable by the user of the dispenser where this actuation element is associated with the drive shaft and is adapted to cause movement of the drive shaft. The drive assembly also includes a span adjustor associated with the drive shaft where this span adjustor is directly connected to the actuation element and adapted to move with respect to the drive shaft to transfer force applied to the actuation element to the drive shaft.
Patent NZ-531369-A (NZ)
Title: A lock gate apparatus with cam moving slider to move bolt with cam able to enter cavity between gate on slider but only exit gate with slider in withdrawn position
Inventor: KEIGHTLEY KYM
IPC: E05B47/00
Filed: 2001-05-18
Abstract: A specific construction for a slider 32 to operate a bolt 14 includes a cavity defined by a pivoting gate 54 on one side and an abutment surface on the other side. An actuation unit includes a cam 54 which interacts with the sliding gate so that the cam can enter the cavity independent of the position of the slider but cannot exit it until the slider has been moved sufficiently towards the right as shown in the drawings where the path swept by the cam does not intersect the gate path.
Patent NZ-532985-A (NZ)
Title: Improvements relating to paperboard
Inventor: KULONEN HEIKKI TAPANI
Filed: 2004-05-18
Abstract: Disclosed is a method for reducing heat induced stickiness of coated paperboard during the production of corrugated board, comprising applying to the coated paperboard, prior to heating, one or more layers of a pigment coating, said pigment coating comprising a bonding agent and a plate-like mineral filler, wherein the amount of plate-like mineral filler in said pigment coating is between about 75% to about 99.5% by weight.
Patent NZ-546490-A (NZ)
Title: A threaded bar adjustable support with left and right handed threads
Inventor: RITCHIE ROBERT
Filed: 2006-04-10
Abstract: A method and apparatus for supporting an overhead structure, such as a pergola, an adjustable vertical distance from a primary structure involves providing an elongate member 10 having first and second oppositely threaded ends, and a formation 15 on the elongate member intermediate the first and second ends for engagement with a tool. The method further involves screwing the first end into a first attachment member 12 and the second end into a second attachment member 14. The first attachment member 12 is connected to the primary structure, and the second attachment member 14 to the overhead structure. The tool is then used to rotate the elongate member 10 so that the first and second ends are simultaneously threaded into their respective attachment members to vary the distance between the overhead structure and the primary structure.
Patent NZ-547453-A (NZ)
Title: A filter for guttering
Inventor: KAKOZ CENAN JOSEPH
IPC: E04D13/076
Filed: 2006-05-25
Abstract: The disclosed guard (1) is used to prevent the entry of leaves and/or debris sufficiently, into the guttering or any other conduit for storm water. The guard (1) comprises of reasonably flexible metal mesh material, which is available in an improved roll form with unique diamond square like openings (10) of sufficient aperture, mainly smaller than the leaves and debris it is too keep out, that prevent the entry of refuse to the guttering and allow for water to flow freely and access the storm water conduit. The guard will allow leaves and debris to slide over it and fall to the ground without entering the gutter channel or conduit. The diamond square like openings (10) on the aperture of the mesh material are aligned in a uniform flat profile (11) on either side allowing either side of the mesh to be used in application. The guard (1) is laid along the length of guttering (3) or conduit and is placed either across the top thereof or within an area, which is located near the top thereof The guard will span at least the opening of the guttering or conduit.
Patent NZ-547702-A (NZ)
Title: Medicinal powder inhaler with a needle for puncturing powder capsules
Inventor: WACHTEL HERBERT
IPC: A61M16/00
Filed: 2004-11-05
Abstract: An inhaler for inhaling powdered medicament from capsules is disclosed. The inhaler comprises a lower part 1. A plate 2 is capable of latching to the lower part, with which the lower part can be closed. A capsule holder 3 receives the capsules which can be countersunk into the lower part. A mouthpiece 4 is able to be latched to the plate. A cover 5 is latched closed by a closure element 6, and covers the mouthpiece in a closed position. The lower part, the plate, the mouthpiece, and the cover are jointed to one another by a single joint 7. An actuating member 8 can be set in motion from a resting position, and thereby co-operates with at least one pin 9 that can be pushed into the capsule holder.
Patent NZ-550426-A (NZ)
Title: Compositions and methods for controlling insects related to the octopamine receptor
Inventor: ENAN ESSAM
IPC: C07K14/435
Filed: 2005-03-21
Abstract: Provided is a method of screening compounds and/or compositions for insect control activity, comprising providing cells expressing an octopamine receptor, or a fragment or derivative thereof, wherein the fragment or derivative binds a biogenic amine, adding said compounds and/or compositions to the cells and measuring the effects of the compounds and/or compositions on the cells.
Patent NZ-551606-A (NZ)
Title: Draghead for a trailing suction hopper and process for dredging by means of this draghead
Inventor: TACK BRUNO
Filed: 2005-08-30
Abstract: Disclosed is a draghead (1) for a trailing suction hopper. The draghead comprises a visor (2), revolvable around a first axis (6) for removing soil, and a suction line (31) connected to the visor (2) for the removal of the loosened soil. The draghead (1) is provided with a pressure plate (21) which comprises a number of mainly disc-shaped penetrating bodies (22) on the soil-facing side of the pressure plate (21), arranged so that their circumferential edge (23) is capable of transferring to forces to the soil.
Patent NZ-552631-A (NZ)
Title: Biochemical synthesis of 1,4-butanediamine
Inventor: EPPELMANN KATRIN
IPC: C12P13/00
Filed: 2005-07-11
Abstract: Disclosed is a process for biochemical synthesis of 1,4-butanediamine in a microorganism having an increased level of an ornithine decarboxylase activity as compared to the native level of ornithine decarboxylase activity, wherein in the microorganism also an increased activity of N-acetylglutamate formation is present as compared to the native level of activity of N-acetylglutamate formation in the microorganism and that 1,4-butanediamine produced in the microorganism is excreted into a fermentation broth, and is recovered from the fermentation broth.
Patent NZ-553044-A (NZ)
Title: Preparations of platinum(II) complexes
Inventor: DU PREEZ JAN GYSBERT HERMANUS
IPC: C07F15/00
Filed: 2005-03-07
Abstract: The disclosure relates to a method for the preparation of a platinum(II) complex containing a neutral bidentate ligand, such as oxaliplatin, wherein the method includes the step of reacting a halogenoplatinum complex containing a neutral bidentate ligand with an oxalate salt in a solvent, wherein more than 1 g/L of the oxalate salt is soluble in the solvent. Also disclosed are specific platinum(II) complexes prepared by this process.
Patent NZ-555225-A (NZ)
Title: Method of manufacturing superconducting tape wire, superconducting tape wire, and superconducting apparatus
Inventor: OHMATSU KAZUYA
IPC: H01B13/00
Filed: 2006-09-07
Abstract: Disclosed is a method for manufacturing a superconducting tape wire (10). The method comprises of the steps of: preparing a tape substrate (11), forming an intermediate thin layer (12) on the substrate, forming a superconducting layer (13) on the intermediate layer, and machining a parting region in the superconducting layer. The parting region is one which does not become superconductive at a critical temperature of the superconducting layer. The parting region can be formed in the intermediate thin layer instead of the superconducting layer, in which a region of the superconductive layer on the parting region does not become superconductive at a critical temperature of the superconducting layer.
Patent NZ-563243-A (NZ)
Title: Headset
Inventor: POLLARD KIERAN
IPC: H04R5/02
Filed: 2007-11-07
Abstract: A headset 1 with ear cups 2 with dual mode speakers. In the first mode the speakers are appropriate for use as headphones as they have a lower volume, and in the second mode the speakers are appropriate for loudspeakers as they have a higher volume. The ear cups 2 have at least one vent for selectively allowing air to pass from inside the ear cup 2 to outside the ear cup 2 when in use.
Patent NZ-566148-A (NZ)
Title: Breathing assistance apparatus
Inventor: CHALVIGNAC PHILIPPE
IPC: A61M16/00
Filed: 2004-03-24
Abstract: An automatic control unit (51) is connected to pressure and flow sensors (111,112) provided at inhalation duct (110) to form a direct closed regulation circuit. The regulation loop for gas source reference value parameter selection is associated with inhalation valve permitting proportional operation, to allow real time control of barometric and volumetric operation modes between inhalation and expiratory phases. (62) Divided Out of 543179
Patent NZ-574422-A (NZ)
Title: TRANSMUCOSAL ADMINISTRATION OF 2,3-DIMETHOXY-5-METHYL-6-(10- HYDROXYDECY L)-1,4-BENZOQUINONE (idebenone)
Inventor: VANKAN PIERRE
IPC: A61K31/122
Filed: 2007-08-03
Abstract: Disclosed is the transmucosal administration of idebenone for the treatment of mitochondrial, neurological or neuromuscular diseases.
Patent NZ-574968-A (NZ)
Title: Bottle closure with two interlocking parts one fitting over the other
Inventor: BROOKS JOHN
IPC: B65D85/72
Filed: 2007-08-17
Abstract: The present disclosure describes a bottle closure for bottles containing liquids at high pressure, such as bottles of sparkling wine, the closure having a first part and a second part, the first part having a portion adapted to receive a portion of an upper section of a neck of the bottle, and a second part that fits substantially over the first part, which is relatively movable with respect to the first part and has at least two positions, a first of which is in a free position and a second of which is in an interlocking position whereby a portion of the second part urges against a portion of the first part receiving the upper section of the neck of the bottle so as to be engaging against an outer side of the said first part to hold it thereby to resist release from its interlocking position with respect to the said neck of an industry standard bottle.
Patent NZ-576333-A (NZ)
Title: Method for producing pradofloxacin
Inventor: ADAM THOMAS
IPC: C07D471/04
Filed: 2007-10-06
Abstract: Disclosed is a process for preparing pradofloxacin of the formula (I) by reacting 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3 -quinolinecarboxylic acid of the formula (II) with (1S,6S)-2,8-diazabicyclo-[4.3.0] nonane of the formula (III) in a solvent mixture of N-methylpyrrolidone and ethanol, wherein the solvent mixture contains 70 to 90 percent by weight of ethanol.
Patent NZ-580176-A (NZ)
Title: Shock absorber insert for a walking aid
Inventor: BASHAM MARSHALL AARON VAUGHN
IPC: A61H3/02
Filed: 2011-04-01
Abstract: Disclosed is a shock absorber insert for a walking aid including a piston cylinder configured to be removably fitted into an internal space of a first support member of the walking aid by friction fit. The piston cylinder includes an abutment surface. The insert also includes a piston rod configured to be removably fitted into an internal space of a second support member of the walking aid and move axially within the piston cylinder. The insert further includes a damper configured to be located on the piston rod and abut the abutment surface to reduce the speed of movement of the piston rod within the piston cylinder. A portion of the piston rod is located within the piston cylinder with a clip configured to be inserted through an aperture in an end of the piston rod which projects through an end wall of the piston cylinder after insertion of the piston rod through the abutment surface of the piston cylinder.
Patent NZ-580492-A (NZ)
Title: Improvements in locks including flush bolts
Inventor: WATTS JOHN RUSSELL
IPC: E05B63/14
Filed: 2008-04-14
Abstract: A lock for a displaceable wing, comprises a casing 2, slide means 20 operatively associated with the casing 2, remote engaging means 192 including a first and/or second remote engaging member 29, and operating means191 including a hand operable lever 110 by which to actuate the slide means 20. The slide means 20 includes a driven slide 21 and a counteracting slave slide 22 supported by the casing 2. Each slide includes a leading end that is displaceable between a relatively most spaced configuration and a relatively least spaced configuration. Each engaging member 29 of the remote engaging means 192 is operably connected by a respective drive member relative to a respective leading end for displacement between an operative and an inoperative configuration. The hand operable lever 110 is adapted to be located substantially within a lever recess when each remote engaging member is in its operative and in its inoperative configurations.
Patent NZ-589972-A (NZ)
Title: Self-propelled ship
Inventor: MOSTERT MAARTEN
IPC: B60L50/10
Filed: 2009-11-09
Abstract: 589972 Disclosed is a self-propelled ship with at least a first shipboard electric network (5), at least one main electrical supply bus, propulsion means (3), at least one drive motor (4) for driving the propulsion means (3), and supply means for supplying with electricity the first shipboard electric network (5) and the drive motor (4) through the main electrical supply bus. The supply means has one set of electric capacitors (10) having a capacitance sized so as to provide, at their nominal electrical charge, at least temporarily, both of the nominal supply of the shipboard electric network (5) and of the nominal electrical supply of the electric drive motor (4) through the main electrical supply bus. Electrical connection means are arranged on board the ship for connecting the set of electric capacitors (10) to another electric network located at an arrival point and/or at a departure point of the ship. This so the capacitors (10) can recharge to their nominal charge and to supply the first shipboard electric network (5) during a stop at the arrival point and/or at the departure point.
Patent NZ-590777-A (NZ)
Title: PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE FOR INHIBITING mTOR
Inventor: BERGERON PHILIPPE
IPC: C07D239/00
Filed: 2009-07-31
Abstract: Disclosed is a compound of Formula I-A e.g. 1-ethyl-3-(4-(4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea or 4-(4-morpholino-7-(pyrimidin-2-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)aniline and tert-butyl 2-(4-aminophenyl)-4-morpholino-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate or a pharmaceutically acceptable salt thereof, wherein for the treatment of cancer.
Patent NZ-591646-A (NZ)
Title: Lighting insertable through fitting aperture of handrail with retaining spring clip to engage inside handrail insertable first
Inventor: ROOS PAUL JAN
IPC: E04F11/18
Filed: 2011-03-09
Abstract: A lighting assembly is disclosed for instal1ing through a fitting aperture defined by a handrail. The 1ighting assembly inc1uding: a retaining element that is removably insertable through the fitting aperture; a body device for providing a light source?the body device comprising a coupling element releasablly engageable to the retaining element; and wherein, with the retaining element inserted through the fitting aperture and located within the handrail insertion of the body device through the fitting aperture enables the coupling element to engage the retaining element thereby releasablly retaining the body device.
Patent NZ-594838-A (NZ)
Title: Timber preservative and method of production
Inventor: MORA NEIL JOSEPH
IPC: A01N33/08
Filed: 2011-08-25
Abstract: Disclosed herein is a timber preservative composition comprising: a boron compound, preferably selected from boric acid, water soluble borates and octaborates, and more preferably at least 65% w/v boric acid; monoethanolamine, preferably between 15% to 25% w/w; and water, preferably between 10% to 20% w/w; wherein the composition has a Boric Acid Equivalent (BAE) of between 45% and 90%, preferably 80% w/v to 90% w/v. Additionally disclosed is a method for preparing a timber preservative composition comprising the steps of: mixing monoethanolamine and water together to form an aqueous solution, and adding a boron compound, preferably as a powder, to the aqueous solution, Additionally disclosed is a method for treatment of timber, said method comprising treating the timber with a timber preservative composition prepared by dilution of a treatment concentrate composition as described herein.
Patent NZ-594966-A (NZ)
Title: Padlock
Inventor: LIGHTFOOT MARK
IPC: E05B67/38
Filed: 2011-09-02
Abstract: A padlock (10) including a padlock body (12), a U-shaped shackle (14), a wheel pack and an opening actuator (72) located within the padlock body. Locking ball bearings (28, 30) are locatable in the shackle legs (68, 70) to secure the shackle (14) in the body. The padlock includes a means to change the unlocking sequence which is protected from tampering by the shackle leg (70) in a locked state. The wheel pack does not interact directly with the shackle (14) but instead interacts via actuator (58).
Patent NZ-598955-A (NZ)
Title: A hydroelectric turbine with coil cooling
Inventor: DUNNE PAUL
IPC: H02K9/19
Filed: 2010-09-29
Abstract: The present disclosure provides provided a hydroelectric turbine having a stator and a rotor, an array of magnets being fixed to rotor and a corresponding array of coils being fixed to the stator, the turbine further including means for cooling the coils during operation of the turbine, the cooling means preferably taking the form of one or more channels passing through the stator, in close proximity to the coils, in order to allow fluid flow through the channels to cool the coils.