baber/WOPTO huggingface dataset:
Patent NZ-232039-A (NZ)
Title: N-substituted-3-acyloxindole derivatives; prodrugs and pharmaceutical compositions
Inventor: MARFAT ANTHONY
IPC: A61K31/38
Filed: 1990-01-08
Abstract: Heteroaryl-3-acyl-2-oxindoles are claimed, of formula (I) where R1 = thienyl, furyl or 2-thiazolyl; R2 = thienyl, furyl or gp. of formula (i), where X = H, F, Cl, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, NO2 or CF3; Y = H, F or Cl; R3 and R4 each = H, F, Cl, Br, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, NO2 or CF3. - Also claimed are prodrugs of (I), e.g., enol esters and ethers of formula (II), where R5 = alkanoyl, cycloalkylcarbonyl, phenylalkanoyl, chlorobenzoyl, methoxybenzyl, phenyl, thienoyl, omega-alkoxycarbonylalkanoyl, alkoxycarbonyl, phenoxycarbonyl, 1-alkoxyalkyl, 1-alkoxycarbonyloxyalkyl, alkyl, alkylsulphonyl, methylphenylsulphonyl, or dialkylphosphonate.
Patent NZ-236186-A (NZ)
Title: Pyrrolidine and piperidine derivatives and pharmaceutical compositions
Inventor: COLLE ROBERTO
IPC: A61P3/00
Filed: 1990-11-22
Abstract: PCT No. PCT/EP90/02011 Sec. 371 Date May 22, 1992 Sec. 102(e) Date May 22, 1992 PCT Filed Nov. 20, 1990 PCT Pub. No. WO91/08206 PCT Pub. Date Jun. 13, 1991.A compound, or solvate or salt thereof, of formula   <IMAGE>   wherein   <IMAGE>    <IMAGE>    R2 and R3 are hydrogen or C1-6 alkyl; R5 together with R4 forms a -(CH)2)2- group optionally substituted by one or two C1-6 alkyl; W is halogen or when A is gem-dimethyl substituted piperidine, is OH; a is 1 or 2, useful in the treatment of pain.
Patent NZ-237705-A (NZ)
Title: Lutenising hormone releasing hormone (lhrh) analogs with cytotoxic moieties
Inventor: SCHALLY ANDREW V
IPC: A61P35/00
Filed: 1991-04-05
Abstract: The present invention deals with LHRH analogs which contain cytotoxic moieties, have influence on the release of gonadotropins from the pituitary in mammals (possess high agonistic or antagonistic activity) and have antineoplastic effect. The compounds of this invention are represented by Formula I: X-R<1>-R<2>-R<3>-Ser-R<5>-R<6>(Q)-Leu-Arg-Pro-R<1><0>-NH2, wherein R<1> is pGlu or D-Nal(2), R<2> is His or D-Phe(4Cl), R<3> is Trp, D-Trp or D-Pal(3), R<5> is Tyr or Arg, R<6> is D-Lys or D-Orn, R<1><0> is Gly or D-Ala, X is hydrogen or a lower alkanoyl group of 2-5 carbon atoms, Q is a cytotoxic moiety having the formula -Q<4> or -A(Q<3>) or B(Q<1>)2 or -B(AQ<2>)2, wherein A is -NH-(CH2)n-CO- or -OC-(CH2)n-CO- where n is 2-6, B is -NH-CH2-(CH2)m-CH(NH)-(CH2)n-CO- where m is 0 or 1, n is 0 or 1, the -CO moiety of A- and of B- being bonded to an amino group on R<6>, and in the group B(AQ<2>)2, the -CO moiety of A-being bonded to an amino group on B, Q<1> is D or L-Mel, cyclopropanealkanoyl, aziridine-2-carbonyl, epoxyalkyl or 1,4-naphthoquinone-5-oxycarbonyl-ethyl, Q<2> is Q<<1>,> anthraquinonylalkoxy or doxorubicinyl, Q<3> is Q<2>, mitomicinyl, esperamycinyl or methotrexoyl, Q<4> is Q<1> or methotrexoyl and pharmaceutically acceptable salts thereof and methods of use pertaining these compounds.
Patent NZ-255752-A (NZ)
Title: Papermaking belt, surface has semicontinuous pattern of protuberances
Inventor: AYERS PETER GRAVES
IPC: D21F11/00
Filed: 1993-08-16
Abstract: A secondary belt for papermaking. The belt has a framework of protuberances arranged in a semicontinuous pattern to provide a semicontinuous pattern of deflection conduits. The semicontinuous pattern is distinguished from the discrete and continuous patterns of the prior art. The protuberances may be generally parallel, or may provide individual cells within the deflection conduits between the protuberances. Also disclosed is the paper made on such a secondary belt.
Patent NZ-295849-A (NZ)
Title: Electrically conductive tape comprising impregnated thermoplastic laminate
Inventor: JORDAN ERICH G
IPC: B29C48/08
Filed: 1995-10-13
Abstract: Electrically conductive tape yarns of two or more layers comprising thermoplastic polymer resin and electrically conductive particles are prepared by a process comprising extruding a multilayer film containing at least one electrically conductive layer and at least one layer substantially free of electrically conductive particles, quenching the film, slitting the film into tapes and orienting the film before or after slitting.
Patent NZ-316874-A (NZ)
Title: Method of and apparatus for off-hook signalling between telephones or adjuncts on the same loop
Inventor: KOS STEVEN
IPC: H04M1/715
Filed: 1996-09-19
Abstract: When two or more telephone sets are in use on the same subscriber's loop, their activities may not be properly detected or monitored by the central office switch. The present invention provides a method of, and an apparatus for, coordinating the signaling activities so that a hook flash or "Link" can work. A telephone set of the invention senses and synchronizes hook flashes of another set on the same loop so that a coordinated hook flash or "LINK" can be properly detected by the office switch.
Patent NZ-331723-A (NZ)
Title: Method and apparatus for generating a transform
Inventor: BRANDIN CHRISTOPHER
IPC: H03M13/01
Filed: 1997-03-04
Abstract: transform generator (20) has an input/output port (22). Coupled to the input/output port (22) is a controller (24). The input/output port (22) receives input transforms and data strings and outputs new transforms. A look up memory (26) is coupled to the controller (24) and is used to determine the new transforms. A shift module (28) and a combiner (30) are also coupled to the controller (24) and are used in combination with the memory (26) to determine a new transform.
Patent NZ-332356-A (NZ)
Inventor: GRIGAT ERNST
IPC: C08L67/02
Filed: 1997-04-07
Abstract: Foamed mouldings are produced from biodegradable polymers selected from the group of aliphatic or partially aromatic polyesters, thermoplastic aliphatic or partially aromatic polyester urethanes, aliphatic or aliphatic-aromatic polyester carbonates and aliphatic polyester amides which are mixed with blowing agents and thermoplastically processed.
Patent NZ-333725-A (NZ)
Title: Keratinocyte growth factor-2 (KGF-2) deletion mutants
Inventor: DUAN ROXANNE
IPC: A61P29/00
Filed: 1997-08-13
Abstract: Various Keratinocyte Growth Factor-2 (KGF-2) N-terminal and C-terminal deletion mutants are described, as are the polynucleotide sequences that encode these mutants. The described polypeptide sequences are useful for stimulating growth and proliferation of keratinocytes and can also promote accelerated wound healing.
Patent NZ-334254-A (NZ)
Title: Heterocyclic metalloprotease inhibitors
Inventor: PIKUL STANISLAW
IPC: A61P19/00
Filed: 1997-08-22
Abstract: A compound having a structure according to Formula (I) wherein:  R1 is H;  R2 is hydrogen, alkyl, or acyl; A is COR3 or SO2R4 wherein R3 is alkoxy, aryloxy, heteroaryloxy, alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino and alkylarylamino and R4 is alkyl, heteroalkyl, aryl, or heteroaryl, substituted or unsubstituted;  X is O, S, SO, SO2, or NR5, wherein R5 is independently chosen from hydrogen, alkyl, heteroalkyl, heteroaryl, aryl, S02R6, COR7, CURS, PO(R9)2 or may optionally form a ring with W or Y; and R6 is alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, diarylamino and alkylarylamino;  R7 is hydrogen, alkoxy, aryloxy, heteroaryloxy, alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino and alkylarylamino;  R8 is alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, diarylamino and alkylarylamino;  R9 is alkyl, aryl, heteroaryl, heteroalkyl;  W is hydrogen or one or more lower alkyl moieties, or is an alkylene, arylene or heteroarylene bridge between two adjacent or nonadjacent carbons (thus forming a fused ring);  Y is independently one or more of hydrogen, hydroxy, SR10, SOR4, SO2R4, alkoxy, amino, wherein amino is of formula NR11,R12, wherein R11 and R12 are independently chosen from hydrogen, alkyl, heteroalkyl, heteroaryl, aryl, SO2R6, COR7, CUR8, PO(R9)2; and  R10 is hydrogen, alkyl, aryl, heteroaryl;  Z is nil, a spiro moiety or an oxo group substituted on the heterocyclic ring and  n is 1-4.  These compounds are useful as metalloprotease inhibitors.
Patent NZ-334702-A (NZ)
Title: Cycloalkyl inhibitors of protein farnesyltransferase
Inventor: DOHERTY ANNETTE MARIAN
IPC: C07K5/06
Filed: 1997-12-16
Abstract: Provided are compounds depicted wherein additionally x is 0 or 1; each R14 is independently H or alkyl; A is -CORa, -CO2Ra', -CONHRa', -CSRa, -C(O)SRa, -C(S)NRa"Ra, -C(S)NHRa', -SO2Ra or -CONRaRa"; R1, R2 and R4 are independently hydrogen or alkyl; and the remaining symbols are provided in the specification. Such compounds are reported to inhibit the farnesyltransferase enzyme, and thus can be used to treat uncontrolled or abnormal proliferation of tissues.
Patent NZ-335419-A (NZ)
Title: multivalent quaternary ammonium salts of a cholinergic agent such as pyridostigmine
Inventor: GRANGER COLIN
IPC: A61P43/00
Filed: 1997-11-10
Abstract: The multivalent quaternary ammonium salts of a cholinergic agent have a plurality of carbamate chemical groupings according to the formula (I) [Y-R-O-CO-NR1R2]+ M-x wherein R is a ring system; Y is optionally substituted alkyl, aryl, or aralkyl or is NR3R4R5; R1 to R5 are independently H or optionally substituted alkyl or aryl; x is an integer greater than 1; all the atoms external to and which covalently link two R's have a neutral charge and M is at least one monovalent anion or a polyvalent anion. These grouping are covalently bound together in any of the following ways: a) through the nitrogen atom to alpha to the carbamate carbonyl and b) through a quaternary nitrogen atom in the ring structure of R. These compounds dissociate under physiological conditions to produce pyridostigmine, neostigmine or edrophonium. The compounds are useful in the treatment of mysasthenia gravis or carpal tunnel syndrome.
Patent NZ-502800-A (NZ)
Title: The use of apoptin in determining the transforming capability of tumorigenic or tumor promoting agents
Inventor: NOTEBORN MATHIEU HUBERTUS MARI
IPC: G01N33/68
Filed: 1998-08-11
Abstract: Method of determining the predisposition of cells to become tumorigenic, wherein normal and/ or cancer-prone cells are provided with inducible apoptin-like activity then subjected to mild tumorigenic activity such as UV or X-irradiation.  Apoptin will only induce apoptosis in cells already transformed/ tumorigenic.  In this manner, the likelihood of a set of cells to lead to cancer can be determined.
Patent NZ-511354-A (NZ)
Title: Methods of treating obesity using a neurotensin receptor agonist or antagonist
Inventor: HADCOCK JOHN RICHARD NEVILLE
IPC: A61K45/06
Filed: 2001-04-26
Abstract: A  neurotensin  receptor ligand such  as  neurotensin, neuromedin  N  or  levocabastine is used to  treat  obesity, diabetes,   sexual  dysfunction,  atherosclerosis,   insulin resistance,        impaired        glucose        tolerance, hypercholesterolemia or hypertrigylceridemia.
Patent NZ-515996-A (NZ)
Title: Microarray fabricating device
Inventor: YAMAGATA YUTAKA
IPC: G01N35/02
Filed: 2001-04-02
Abstract: A device for mass-production manufacture of a high-density microarray for cDNA or protein, comprising an electro-spraying means to spray in sequence a plurality of solutions, supporting means for supporting a plurality of sample chips which will be sprayed with the electro-spray, masking means disposed between said spraying means and said supporting means and having a number of holes equal to the number of sample chips, shifting means for shifting said supporting means and said masking means to allow simultaneous deposition of the sample solutions onto the plurality of sample chips.
Patent NZ-532709-A (NZ)
Title: Gamma radiation to enucleate avian eggs efficiently to enable donor nucleus transfer
Inventor: SANG HELEN
IPC: A01K67/027
Filed: 2002-12-13
Abstract: A method of enucleating an egg by exposing the egg to gamma irradiation is described. The dose of gamma irradiation used is sufficiently high to halt development of the egg or embryo derived therefrom directed by the nucleus of the irradiated egg, but sufficiently low to enable development of the egg or embryo directed by a nucleus transferred into the enucleated egg.
Patent NZ-532856-A (NZ)
Title: Integrated hydroponic and fixed-film wastewater treatment systems and associated methods
Inventor: AUSTIN DAVID C
IPC: C02F3/12
Filed: 2002-11-14
Abstract: The wastewater treatment systems have a plurality of treatment zones including a first reactor for supporting biofilms for reducing a concentration of organics and solids from wastewater to be treated and for cyclically nitrifying and denitrifying the wastewater therein. A second reactor is for supporting biosolids, the supporting means including elements for digesting suspended solids in water exiting the first reactor. A portion of the water exiting the second reactor is recycled to the first reactor.
Patent NZ-538779-A (NZ)
Title: Connector assembly with improved retention features
Inventor: MTCHEDLISHVILI GEORGE
IPC: H01R13/62
Filed: 2005-03-11
Abstract: A connector assembly (100) provides locking and retention through the use of a cylindrical body (102) having locking arms (104) extending therefrom and a malleable collar (106) that includes an integrally molded interior lip (114) and exterior bumps (116). The malleable collar is slid over a portion of the cylindrical body such that the bumps align with the locking arms. Upon insertion of the connector into a housing receptacle, the locking arms compress the bumps thereby providing resistance to aid with retention while the interior lip abuts the cylindrical body which facilitates sealing the receptacle.
Patent NZ-539584-A (NZ)
Title: Method and apparatus for maintaining and monitoring sleep quality during therapeutic treatments
Inventor: BURTON DAVID
IPC: A61N1/365
Filed: 2003-10-09
Abstract: A method of controlling a gas delivery device is disclosed. The method includes the steps of: (a) setting a rate of fluid flow, (b) monitoring a physiological parameter of a subject that is an indicator of arousal, (c) determining if the monitored physiological parameter indicates onset of arousal, and (d) adjusting the rate of fluid flow to avoid arousal.
Patent NZ-551038-A (NZ)
Title: Stand-up pouch, and a method for the production thereof
Inventor: GUENTER WALTER
IPC: B65D65/40
Filed: 2005-05-13
Abstract: A stand-up pouch having a stand-up pouch body and a stand-up pouch base, especially a standing base, is provided. At least the stand-up pouch body comprises a laminate including at least one unidirectionally stretched film, wherein the thickness of the unidirectionally stretched film is greater than the overall thickness of the remaining further layers of the laminate.
Patent NZ-552816-A (NZ)
Title: Formulation for transdermal administration of antihyperthyroid drug comprising a penetration enhancer selected from oleic acid, d-limonene, pyrrolidones, a C2-C8 alcohol, glycol ethers, triacetin and combinations thereof
Inventor: NANJAN KARTHIGEYAN
Filed: 2007-01-24
Abstract: Disclosed is a composition of an anti-hyperthyroid drug, includingan aprotic polar solvent, a polyol, and a fatty acid, and a method of manufacturing this composition. Also disclosed is the use of this composition for treating hyperthyroidism in animals, such as cats.
Patent NZ-552942-A (NZ)
Title: Moisture detection
Inventor: HOLYOAKE IAN CONRAD
Filed: 2005-08-02
Abstract: A method of retrofitting a moisture detection fitting (1) in the wall of a building in accordance with the following steps: a) forming a space which proceeds into the wall, b) inserting the moisture detection fitting (1) into the space such that a probe (4) of the fitting: i) presses into timber framing within the wall, or ii) stops short of timber framing within the wall but contacts a moisture absorbent filler (18) forming part of the fitting wherein the filler contacts the timber framing to absorb moisture from the timber framing, the moisture detection fitting being fitted substantially permanently such that when it is in use a moisture detection device can be detachably connected to the fitting outside the wall and use the probes, and if appropriate the filler, to measure a moisture content of the timber framing.
Patent NZ-553244-A (NZ)
Title: Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses
Inventor: DAVIES HEATHER L
IPC: A61K39/00
Filed: 2005-07-18
Abstract: Disclosed is a medicament, comprising (a) an oligonucleotide, (b) an immune stimulating complex, and (c) an antigen, wherein said immune stimulating complex comprises saponin and sterol and said medicament induces an interferon-gamma response when administered to a vertebrate subject.
Patent NZ-554925-A (NZ)
Title: insecticidal composition comprising novaluron and imidacloprid and/or acetamiprid
Inventor: BARAZANI AVNER
IPC: C07C/
Filed: 2005-10-31
Abstract: Disclosed is a insecticidal composition comprising (a) at least one insecticidal compound with effective knock-down action selected from the group (A) consisting of imidacloprid and acetamiprid, and (b) at least one insecticidal compound with effective long-term action comprising novaluron, for the use in insect control in crops, and locus thereof. Also disclosed is a method for insect control in crops and locus.
Patent NZ-560769-A (NZ)
Title: Pointing systems for addressing objects
Inventor: ELLENBY THOMAS
IPC: H04W4/20
Filed: 2001-10-29
Abstract: Systems are arranged to provide a user information which relates to objects of interest. A user may point a device toward an object to address it. The device determines which objects are being addressed by reference to an internal database containing pre-programmed information relating to objects. Information relating to objects being addressed can then be presented at a user interface. A device of the system may include a point reference, a direction reference, a position determining support, attitude determining support, a computer processor and database, and a user interface.
Patent NZ-565878-A (NZ)
Title: 2,5-substituted 3-undecyl-1,4-benzoquinones
Inventor: UPADHYAY SHAKTI
IPC: A61Q90/00
Filed: 2005-09-19
Abstract: Disclosed is the use of 2,5-dihydroxy-3-undecyl-p-benzoquinine or an analog thereof having the formula (I), wherein the substituents are as defined in the specification, optical isomers thereof, polymorphs thereof, and pharmaceutically acceptable esters, ethers, carbamates, oximes of said compounds, said isomers of said polymorphs, salts, solvates and hydrates thereof, in the manufacture of a medicament for use in a method for treatment, amelioration or prevention of a disease or condition mediated by a lipase gene family enzyme, including obesity, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, pancreatitis, diabetes, atherosclerosis, other cardiovascular diseases, metabolic syndromes and metabolic disorders. Cosmetic methods for the skin and hair are also provided. Certain novel compounds of formula (I) are also disclosed.
Patent NZ-567221-A (NZ)
Title: Anticoagulant antithrombotic dual inhibitors comprising a biotin label
Inventor: DE KORT MARTIN
IPC: C07H15/26
Filed: 2006-10-06
Abstract: Disclosed is an antithrombotic compound of the formula I wherein the oligosaccharide is a negatively charged oligosaccharide residue of Formula B, wherein R1 is OCH3 or OSO3-, the charge being compensated by positively charged counterions; the spacer is an essentially pharmacologically inactive linking residue; the GplIb/lIIa antagonist is a residue derived from tirofiban (MK 383) or a pharmaceutically acceptable salt thereof; wherein the spacer of the compound of formula I comprises a covalent bond with a biotin label or analogue thereof. Also disclosed is use of said antithrombotic compound for the manufacture of a medicament for treating or preventing thrombosis or other thrombin-related diseases and a pharmaceutical composition comprising said compound.
Patent NZ-569683-A (NZ)
Title: A method and system for measuring organisational culture
Inventor: BASSER IAN
IPC: G06Q10/00
Filed: 2007-01-09
Abstract: A method and a computer system for measuring the culture of an organisation are disclosed. A plurality of categories relating to the culture of the organisation is established with the categories being grouped into a plurality of clusters. Each cluster includes a selected one or more of the categories relating to a corresponding predetermined aspect of organisational culture. The system includes input means for receiving information provided by a plurality of individuals associated with the organisation regarding each the individual's personal experience of the culture of the organisation in relation to each of the categories; a processor for processing the received information to determine, with regard to each category, a corresponding category grade representing an extent to which the experience of the individuals is either positive or negative; and output means for generating a chart which includes graphical representations of each one of the clusters. Each the cluster graphical representation includes graphical representations of the category grades determined for the categories grouped within the corresponding cluster.
Patent NZ-580798-A (NZ)
Title: A solar collector without manifold
Inventor: PELAN RICHARD
IPC: F24S10/70
Filed: 2008-05-30
Abstract: A solar collector comprises a solar absorbing tube (3) containing elongate tube (11) that extends out of one end of the solar absorbing tube and into an end fitting (15). An annular outer passageway of the elongate tube communicates with a cold fluid inlet conduit (16) within the end fitting, and the inner passageway of the elongate tube communicates with a hot water outlet conduit (17) within the end fitting. Each end fitting is provided with a receiving portion (22) for receiving an end of the concentric elongated tube. The end fittings are interconnected to provide fluid flow paths without the need for a manifold. Any number of solar collector tubes can be interconnected in this way.
Patent NZ-580946-A (NZ)
Title: Audio Cable with particles disposed between a conductor and a sheath
Inventor: HARDIE PETER
IPC: H01B3/00
Filed: 2010-12-02
Abstract: Disclosed is a cable designed to transmit audio signals with reduced vibration within the cable to increase fidelity of the signal. The cable comprises a conductor (2), a sheath (8) surrounding the conductor, and a plurality of particles (4) disposed between the conductor and the sheath. The cable has plurality of air gaps (6) between the plurality of particles.
Patent NZ-583490-A (NZ)
Title: Hydrophilic biodegradable adhesives
Inventor: SMITH JASON
IPC: C09J175/04
Filed: 2008-07-07
Abstract: Disclosed is an adhesive comprising the reaction product of (a) an isocyanate component having an average functionality of at least 2, wherein the isocyanate component is selected from the group consisting of lysine diisocyanate and derivatives thereof, lysine triisocyanate and derivatives thereof, and combinations thereof (b) an active hydrogen component having an average functionality greater than 2.1, wherein the active hydrogen component comprises a hydroxyl-functional component; and (c) an ionic salt component having an average hydroxyl or amino functionality, or combination thereof, of at least 1, wherein the ionic salt component is selected from the group consisting of ammoniates, halides, sulfonates, phosphonates, carboxylates, and combinations thereof, wherein the adhesive is moisture-curable and biodegradable.
Patent NZ-585697-A (NZ)
Title: 2-propynyl adenosine analogs with modified 5'-ribose groups having A2A agonist activity
Inventor: RIEGER JAYSON M
IPC: A61K31/7076
Filed: 2005-08-02
Abstract: Disclosed is a compound of formula (I) where X is a heterocyclic group containing at least one hetero atom selected from O, S(O)p and N(R8), the other substituents are as disclosed in the description. The compounds are useful as A2A agonists. Also disclosed is a composition comprising a compound of formula (I) and the use of a compound of formula (I) for the manufacture of a medicament for treating diseases or condition responsive to the inhibition of an inflammatory response.