baber/WOPTO huggingface dataset:
Patent CA-2463733-A1 (CA)
Inventor: HORNICK CONRAD A
IPC: C08B37/00
Filed: 2002-08-30
Abstract: Noni juice and a protein-free, alcohol precipitate of Noni juice inhibited angiogenesis in in vitro human angiogenesis models. When growth medium contained Noni juice at least over the range from about 2.5% to about 33% (b y volume), angiogenesis was blocked. Moreover, Noni juice and an ethanol precipitate were able to destroy a pre-existing angiogenic response as well as prevent the development of new vessels. Noni juice was effective in inhibiti ng the growth of angiogenic vessels from breast cancer explants. It will also b e effective in treating cancers and non-cancerous diseases whose response includes an increase in angiogenesis, e.g., retinopathy of prematurity, neovascular glaucoma, diabetic retinopathy, and psoriasis. The primary antiangiogenic component is believed to be a carbohydrate with a molecular weight less than about 6000 Daltons. In an initial experiment, oral administration of Noni juice appeared to adversely affect the antioangiogeni c component(s) in the juice.
Patent CA-2466059-A1 (CA)
Inventor: PHAM ANH NGOC
IPC: F16J1/18
Filed: 2002-12-19
Abstract: A crosshead piston assembly (10) has a piston with an upper head portion (22 ) and a lower stem portion (24) formed with a pin bore (48). The pin bore has a pair of lower, laterally spaced mounting ears (52) presenting a bearing support surface interrupted by a lateral gap (56) between the ears. A saddle (60) is arranged opposite the ears and provides a bearing support surface (6 2) which is continuous along the pin bore. A three-piece slipper bearing set (1 4) is disposed in the pin bore and includes a pair of lower bearing shells (68) seated in the ears and an upper bearing shell (70) seated in the saddle. The upper bearing shell and saddle are formed with aligned oil supply (76) and retaining (80) holes, The oil supply hole is maintained fully open, while a retaining pin (84) is installed in the aligned retenting holes.
Patent CA-2468845-A1 (CA)
Title: Stabilized reverse micelle compositions and uses thereof
Inventor: CONSTANTINIDES PANOS P
IPC: A61K9/107
Filed: 2002-12-03
Abstract: The invention relates to compositions and methods for drug delivery suitable for promoting the transmucosal absorption of drugs, especially drugs with poor intrinsic bioavailability, such as peptides, proteins, vaccines, and nucleic acids. The delivery system of this invention preferably comprises fatty acid esters and their hydrophilic derivatives that associate with water and other polar solvents to form reverse micelles tha are physiclally stabilized in the presence of gastrointestinal fluid, water, and other hydrophilic solvents.  Such stable reverse micelles are formed by suitable mixtures of polymeric or non-polymeric compounds with amphiphiles. Micelles made using these methods undergo phase transformation more slowly resulting in delayed drug release profiles and sustained absorption. When administered as a pharmaceutical to mucosal surfaces following oral ingestion or intranasal administration, therapeutic molecules principally solubilized in the aqueous phase are protected from digestion by mucosal enzymes and other mucosal degradative processes and are taken up by absorptive cell mechanisms and reach appropriate body compartments. The reverse micelle compositions may comprise mono-, di-glycerides and/or their transesterifed products containing C6-C12 fatty acids chains, wherein the transester groups consist of hydrohilic moieties.
Patent CA-2468931-A1 (CA)
Title: Booster amplifier for cellular telephone cradles
Inventor: FRIESEN ELWOOD DALEN GRANT
IPC: H04B1/38
Filed: 2001-12-12
Abstract: A booster amplifier that can be coupled to virtually any cellular telephone handset is provided for use with virtually any cellular communications network. The power output of the booster amplifier is dynamically controlled based upon signals received from the handset to improve the quality and range of communications between the handset and the base stations of the cellular network without interfering with normal communications between the cellular network and other handsets.
Patent CA-2472380-A1 (CA)
Inventor: CHAO HUNG-CHANG
IPC: B62K3/10
Filed: 2004-06-01
Abstract: A portable bicycle comprises a front bar having a front end coupled to a head tube, a rear frame section including a lower seat tube extended upwardly from a bottom bracket, a upper seat tube spaced and aligned with the lower seat tube, and a hollow rear bar for slidably receiving the front bar, the rear bar being intersected the upper and lower seat tubes, and a fastening mechanism for securing the front bar to the rear bar. Detaching a seat post and a saddle, unfastening the fastening mechanism, fully projecting the front bar from a rear opening of the rear bar, and fastening the fastening mechanism will shorten the distance between front and rear wheels to a minimum and facilitate the bicycle to store or carry in a much reduced size.
Patent CA-2472496-A1 (CA)
Inventor: WHIPPLE RODGER E
IPC: F26B13/10
Filed: 2002-12-20
Abstract: A combination ultraviolet curing and infrared dryer system which allows both an ultraviolet curing unit to be used at the same tme an infrared dryer is used. The infrared dryer and ultraviolet curing unit are placed in an enclosure having a cooling system which cools both the ultraviolet curing unit and the infrared dryer. The cooling system may comprise an air supply system, or may comprise an air supply system and a water cooling system.
Patent CA-2473255-A1 (CA)
Title: Rock bolts with expandable element
Inventor: BOEHM KARL
IPC: E21D20/00
Filed: 2003-01-21
Abstract: In a method and device for drilling, in particular impact drilling or rotary percussion drilling, a hole in soil or rock material and forming an anchorage in said hole, wherein a bore hole is formed by the introduction of a drill bit (2), it is provided that the drill rod assembly of the drilling device is comprised of at least one expandable element (3, 4) having at least one hollow space extending substantially in the longitudinal direction of the bore for introducing a fluid under pressure to at least partially widen the outer periphery of the expandable element (3, 4), and/or the drill rod assembly is connected with at least one expandable element (3, 4) each including at least one hollow space substantially extending in the longitudinal direction of the bore for introducing a fluid under pressure to widen the outer periphery, thus ensuring a safe anchorage by the expansion of the expandable elements (3, 4) both over the periphery and over the length of the device at a simplified overall construction.
Patent CA-2475959-A1 (CA)
Inventor: GUROVICH VALERY
IPC: G06F19/00
Filed: 2003-02-06
Abstract: Une installation médicale (30) et une pharmacie (20) forment un réseau utilisant des connexions Internet (45, 52, 50, 55) normalisées et téléphoniques (40) comprenant des ordinateurs (26, 34) au niveau de chaque emplacement. Un système (10) de reconnaissance vocale est intégré dans le réseau afin d'obtenir des services de prescription désirés par commande vocale.
Patent CA-2476293-A1 (CA)
Inventor: CHUN JOONG H
IPC: E01C11/24
Filed: 2002-10-15
Abstract: A high traction, anti-icing road cover system for covering a road surface (3) or bridge deck (2), is provided with a plurality of individual covers (12) placed to correspond with tire track locations tollowed by vehicles (4). Control and supply systems (10, 14) are deployed on a service pole (5) adjacent the bridge deck (2). Electricity is supplied the covers via sockets (9), cabel (19) and power conductors (7) and control box (16). Anti-icing chemicals are provided to the covers (12) via storage container (15), distribution box (8), supply tubes (6, 18) and control valve (17).
Patent CA-2477423-A1 (CA)
Title: Aminoalkylphosphonates and related compounds as edg receptor agonists
Inventor: HALE JEFFREY J
IPC: A61K31/4196
Filed: 2003-02-27
Abstract: The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
Patent CA-2480856-A1 (CA)
Title: Substituted aryl amides
Inventor: HAGMANN WILLIAM K
IPC: A61K31/517
Filed: 2003-04-01
Abstract: Novel compounds of structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as psychotropic drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson s disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as, the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.
Patent CA-2482683-A1 (CA)
Inventor: ROEDERS JUERGEN
IPC: B23Q11/00
Filed: 2003-05-07
Abstract: The invention relates to a weight-compensating device comprising a support ( 1) and a component (2) which is mounted on the support (1) and is movable particularly in a vertical direction by means of a drive unit. The inventive weight-compensating device is characterized by the fact that at least one negative pressure body (3) is disposed between the support (1) and the component (2), said negative pressure body being modifiable in length and being connected to a source of negative pressure in order to compensate the weight acting on the component (2).
Patent CA-2484458-A1 (CA)
Title: Zinc powder or zinc alloy powder for alkaline batteries
Inventor: SCHULZ NORBERT
IPC: B22F1/00
Filed: 2003-03-25
Abstract: The invention is directed to a zinc powder or zinc alloy powder for alkaline batteries, which powder has a grain size distribution wherein 60 to 100 wt.-%  of the particles, relative to the zinc powder or zinc alloy powder, have a diameter of from 40 to 140 µm. The invention is also directed to an alkaline battery.
Patent CA-2485031-A1 (CA)
Title: Systems and methods for identifying fraud and abuse in prescription claims
Inventor: ROWE JAMES COUSER III
IPC: G16H20/10
Filed: 2003-05-16
Abstract: Systems and methods permit the identification of fraud and abuse in electron ic prescription transactions by intercepting and analyzing prescription claims to determine the likelihood that a claim is fraudulent. A fraud scoring engine (122) utilizes a compilation of expert rules (104, 134, 105) and profiling engine methodologies to determine the likelihood that a transaction is the result of fraudulent or abusive behavior. The fraud scoring engine (122) assigns a fraud score to rate the probability that a transaction is fraudule nt in nature. The fraud score is compared against payer-defined business rules (105, 134) to determine if a claim is rejected as fraudulent. A fraud management interface enables payers to view a rejected claim and the reasons why a claim is rejected so that the reasons can be explained to a pharmacist , should the pharmacist contact the payer.
Patent CA-2491987-A1 (CA)
Inventor: HIVELY LEE M
IPC: G01M99/00
Filed: 2003-07-01
Abstract: This invention teaches further method improvements to forewarn of critical events via phase-space dissimilarity analysis of data from biomedical equipment, mechanical devices, and other physical processes. One improvement involves conversion of time-serial data into equiprobable symbols. A second improvement is a method to maximize the channel-consistent total-true rate o f forewarning from a plurality of data channels over multiple data sets from t he same patient or process. This total-true rate requires resolution of the forewarning indications into true positives (TP), true negatives (TN), false positives (FP) and false negatives (FN) relative to a forewarning window 20. A third improvement is the use of various objective functions, as derived from the phase-space dissimilarity measures, to give the best forewarning indication. A fourth improvement uses various search strategies over the phase~space analysis parameters to maximize said objective functions. A fift h improvement shows the usefulness of the method for various biomedical and machine applications.
Patent CA-2493888-A1 (CA)
Inventor: SAMPALIS FOTINI
IPC: A23L1/30
Filed: 2002-07-29
Abstract: A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty acid, metals and a novel flavonoid.
Patent CA-2494110-A1 (CA)
Title: Point attachment systems for laminated glass and a process for preparing same
Inventor: SANDEN BJORN A
IPC: C09J201/00
Filed: 2003-07-31
Abstract: The present invention is a direct-point attachment glazing (bolted glass) system (20) comprising: (1) a polymer interlayer (28); (2) at least one shee t of glass (24); (3) at least one receptor for an attachment means; and (4) at least one attachment means, wherein the polymer interlayer (28) is bonded on at least one surface to at least one sheet of glass (24), and wherein at lea st one receptor (22) is adhesively bonded to the glass by the polymer interlaye r (28) in such a way that the receptor (28) is positioned to mechanically acce pt the attachment means.
Patent CA-2495420-A1 (CA)
Inventor: SMALLEY BRIAN LESLIE
IPC: B65D5/72
Filed: 2003-07-31
Abstract: There is provided a paperboard carton for receiving articles in two or more layers separated by a divider pad (29), which is secured relative to an end panel arrangement (22) at one end of the carton. The carton has a top panel (13), a base panel (16) and a pair of opposite sides (15). One of the side panels (15) has a removable portion adjacent one end which when removed defines a roll out aperture for article removal when the carton is lying on said one end panel arrangement.
Patent CA-2497895-A1 (CA)
Inventor: RONFARD VINCENT
IPC: A61K35/36
Filed: 2003-09-05
Abstract: The present invention relates to fibrin cell supports for cell cultures form ed by the mixture of plasma proteins including fibrinogen and thrombin. The fibrin cell supports are preferably used for preparing a culture of cells su ch as keratinocytes, recovering the culture in the form of a reconstituted tissue, and transporting same. The reconstituted tissue is particularly suitable for use as a skin graft.
Patent CA-2497929-A1 (CA)
Inventor: MORRISON JAMES E
IPC: B01D19/00
Filed: 2003-08-20
Abstract: A downhole separator has a housing defining an interior cavity divided into a first chamber and a second chamber by a flow restricting bearing housing. A shaft driven impeller pumps production fluid into the first chamber and to t he bearing housing. The bearing housing generates a pressure drop in production fluid entering the second chamber, separating gas from liquid. A vortex generator in the second chamber segregates the liquid to the outside and the gas to the inside of the second chamber. A downhole separation method includ es pumping production fluid into a first chamber, and generating a pressure dro p in the fluid as the fluid enters a second chamber to separate gas and liquid .
Patent CA-2498751-A1 (CA)
Inventor: TING KANG
IPC: A61K38/00
Filed: 2003-09-15
Abstract: La présente invention a trait à la découverte que le gène <I>NELL-1</I> humain induit ou produit une régulation positive de la minéralisation osseuse. Le gène ou produit génétique NELL-1 procure ainsi une cible appropriée pour le criblage de modulateurs de la minéralisation osseuse. En outre, le gène NELL-1 peut être utilisé pour faciliter la réparation de fractures de l'os et/ou pour accroître de manière générale la densité osseuse.
Patent CA-2500122-A1 (CA)
Inventor: ABBEELE VAN DEN HENK JAN FRANS
IPC: C08F8/32
Filed: 2003-10-06
Abstract: La présente invention concerne une dispersion polymère aqueuse comprenant un copolymère d'unités monomères d'anhydride et d'unités monomères vinyliques , ce copolymère ayant été soumis à une réaction d'imidisation. Cette invention concerne aussi un procédé de production et d'utilisation de cette dispersion.
Patent CA-2501866-A1 (CA)
Title: Swivel joint system
Inventor: GHILARDI JEAN-PIERRE
IPC: F16L59/18
Filed: 2003-10-10
Abstract: The invention concerns a swivel joint system designed to be mounted in a cryogenic liquid transfer line, such as liquefied natural gas, and the return of cold gas associated with the cryogenic liquid transfer. The system is of the type comprising a swivel joint for the passage of the cryogenic liquid and a swivel joint for the return of the cold gas, each device comprising a conduit (12, 29) provided with a fixed conduit portion (12a, 29a) and a conduit portion rotating (12b, 29b) relative to the fixed conduit portion and rotational guiding means (44) interposed between the two conduit portions. The system is characterized in that the swivel joint device for the passage of the gas return is integrated in the swivel joint device for the passage of the cryogenic liquid. The invention is useful for offshore stations.
Patent CA-2502133-A1 (CA)
Title: Method of forming a biopsy device
Inventor: TSONTON MARK
IPC: A61B5/055
Filed: 2005-03-22
Abstract: A method for forming a needle assembly is provided. A distal portion of the needle can be formed of a first material which does not interfere with MRI imaging of a tissue receiving port disposed in the distal needle portion. A proximal needle portion can be formed of a second, different material, such as a metal. The proximal needle portion can provide strength and stiffness.
Patent CA-2503078-A1 (CA)
Title: Assay for determining the activity of fatty acid amide hydrolase
Inventor: MAZUR CURT
IPC: B01D/
Filed: 2003-10-21
Abstract: The invention provides methods of assaying fatty acid amide hydrolase (FAAH) activity adaptable for high throughput screening. The methods provide for separating a labeled substrate from at least one labeled hydrolysis product, the separation facilitating the quantification. The invention also provides methods of identifying a compound to be tested as an inhibitor or an activat or of FAAH activity through the addition of the compound to be tested to a reaction mixture and comparison of the enzyme activity in the presence and absence of the compounds to be tested. The methods are adaptable for use in detecting altered FAAH activity in patients, for example, those at risk for in vitro fertilization failure, or at risk for, or suffering, addictions.</SDOA B>
Patent CA-2503129-A1 (CA)
Inventor: HSU WINDSOR WEE SUN
IPC: G06F11/10
Filed: 2003-10-17
Abstract: Selon l'invention, des données stockées peuvent être récupérées à partir d'un réseau de disques comprenant au moins 2n + 1 disques physiques permettant de stocker l'équivalent de n disques physiques de données lorsque deux disques présentent une défaillance ou lorsque plus de deux disques dépendants présentent une défaillance. Les données sont stockées dans des zones de données divisées en n bandes de taille sensiblement égale et réparties sur les n disques. Chaque zone de données comprend une bande de parité correspondante générée par inclusion des bandes de données dans la zone de données une fois seulement que la bande de parité est générée. Les bandes de données de chaque zone de données, la copie de chaque bande de données et la bande de parité correspondante sont réparties sur les disques de sorte que les bandes de données de chaque zone de données, la copie de chaque bande de données et la bande de parité correspondante soient chacune sur un disque respectivement différent du réseau de disques.
Patent CA-2503969-A1 (CA)
Inventor: HENDERSHOT WILLIAM B
IPC: E21B43/00
Filed: 2005-04-05
Abstract: Oil shale is utilized to generate electricity at the site of the oil shale deposit. Oil shale is removed from an oil shale deposit and provided to a burn container. Hydrocarbons contained in the oil shale are combusted in the burn container to generate thermal energy. The thermal energy is utilized to heat water to generate steam. The steam is utilized to drive a steam turbine power generator located in close proximity to the oil shale deposit to generate electricity. The electricity is distributed off-site using a conventional distribution system. At least a portion of the electricity generated on site may be utilized in the energy recovery process to make it self-sustaining.
Patent CA-2504233-A1 (CA)
Title: Concentric radii ball bearing stack
Inventor: THOMPSON STEPHEN
IPC: F16C33/60
Filed: 2005-04-18
Abstract: A ball bearing stack which includes more than one bearing arranged in face t o face relation and sharing a common rotational axis. Each bearing has an inner rin g and a concentric outer ring. The inner ring defines an inner race. The outer ring defines an outer race. A plurality of ball bearings are captured within an annular space defined between the inner race and the outer race. Each of the more than one bearing has a ball bearing contact surface on the outer race which is radiused from face to face about a common centre point positioned on the common rotational axis.
Patent CA-2508194-A1 (CA)
Inventor: MACKENZIE SIMON JOHN
IPC: A61P25/14
Filed: 2003-12-01
Abstract: It is intended to provide PDE10A inhibitors which are useful in preventing o r treating Parkinson~s disease, Huntington~s disease, Alzheimer~s disease or integration dysfunction syndrome. A phosphodiesterase 10A inhibitor characterized by containing, as the active ingredient, a pyrazolo[1,5- a]pyridine derivative represented by the following general formula (1) is useful in preventing or treating Parkinson~s disease, Huntington~s disease, Alzheimer~s disease or integration dysfunction syndrome: (1) wherein R1 and R2 independently represent each hydrogen or C1-4 lower alkyl; and R3 represents hydrogen, C1-4 lower alkyl or C1-3 lower alkoxy.
Patent CA-2508448-A1 (CA)
Title: Procede de moulage d'article en mousse a base de resine
Inventor: HIRAMATSU MASAYA
IPC: B29C33/14
Filed: 2003-12-05
Abstract: L'invention concerne un procédé de moulage d'un article en mousse à base de résine permettant d'améliorer l'ouvrabilité de manière remarquable pour le démoulage, l'article en mousse à base de résine, de type coussin de siège, pouvant être démoulé d'une matrice de moulage par glissement le long de la surface intérieure de cette dernière; ainsi que la matrice de moulage utilisée dans ce procédé. Dans cette matrice de moulage, des saillies de verrouillage (20, 30) et une partie poche (40) sont disposées sur la surface intérieure de la partie centrale (3) de ladite matrice de moulage; la face (10a) d'un élément de moulage solidaire (10) est opposée à la partie centrale (3), est en chevauchement par rapport à la surface de cette dernière de façon que les saillies (20, 30) se placent dans de grands orifices (12), et glissent de manière à amener lesdites saillies (20, 30) à occuper des parties étroites (13) et larges (14) afin que ledit élément de moulage solidaire (10) soit tenu sur ladite partie centrale (3). La partie d'extrémité de l'élément de moulage solidaire (10) est placée dans la partie poche (40). Lors du démoulage, l'article en mousse à base de résine glisse dans le sens inverse au sens de glissement.