baber/WOPTO huggingface dataset:
Patent CA-2320783-C (CA)
Title: Retracting needle syringe
Inventor: CIPOLETTI ROBERT
IPC: A61M5/315
Filed: 2000-01-04
Granted: 2008-04-01
Abstract: A retracting needle syringe includes a barrel having a chamber, an open proximal end and an open distal end. A plunger is slidably positioned in fluid-tight engagement with an inside surface of the barrel. The plunger has an elongated cavity in its distal end and a cover element sealing the cavity. A needle assembly at the distal end of the barrel includes a needle cannula having an inner hub having an open proximal end and a distal end connected to the needle cannula so that the lumen of the cannula is In fluid communication with the chamber. A flange on the Inner hub is connected to a proximal end of an outer hub so that the needle cannula projects distally outwardly from a distal end of the outer hub. A  spring is contained between the inner hub and the outer hub. A circular release element is movably connected to a proximal end of the flange. The release element has a distal end and a sharp proximal end projecting into the chamber, wherein distal motion of the plunger will cause the sharp proximal end to cut through the cover element and the distal end of the release element to dissociate an outer portion of the flange from an inner portion of the flange allowing the spring to expand and move the needle cannula into the cavity.
Patent CA-2321254-C (CA)
Title: Pyradazine derivatives having inhibitory activity against interleukin-1.beta. production
Inventor: KOTAKI KYOKO
IPC: A61P37/00
Filed: 1999-02-26
Granted: 2008-12-09
Abstract: Pyridazine derivatives represented by general formula (1) or salts thereof, wherein R1 represents lower alkoxy, lower alkylthio or halogeno; R2 represents H, lower alkoxy, lower alkylthio or halogeno; R3 represents OH, CN, halogeno, lower cycloalkyl, lower alkyl or lower alkenyl optionally substituted by an optionally substituted aromatic group or optionally substituted carbamoyl; R4 represents COOH, lower alkoxycarbonyl, optionally substituted carbamoyl, optionally substituted amino or optionally substituted ureido; and the broken line means a single bond or a double bond between the carbon atoms at the 4- and 5-positions. Because of having an excellent effect of regulating interleukin-1.beta. production, these compounds are useful as preventives/remedies for immunologic diseases, inflammatory diseases, ischemic diseases, etc.
Patent CA-2322559-C (CA)
Inventor: ISNER JEFFREY M
IPC: A61K35/44
Filed: 1999-03-09
Granted: 2012-07-17
Abstract: The present invention generally provides methods for modulating formation of new blood vessels. In one embodiment, the methods include administering to a mammal an effective amount of granulocyte macrophage-colony stimulating factor (GM-CSF) sufficient to form the new blood vessels. Additionally provided are methods for preventing or reducing the severity of blood vessel damage in a mammal which methods preferably include administering to the mammal an effective amount of GM-CSF. Provided also as part of this invention are pharmaceutical products and kits for inducing formation of new blood vessels in the mammal.
Patent CA-2334685-C (CA)
Inventor: COPE ROBERT L III
IPC: A61M16/00
Filed: 1999-06-21
Granted: 2008-09-02
Abstract: A gas outlet apparatus (10) is configured to provide a medical gas outlet for a gas supply line (62). The apparatus (10) includes a front cover (12) formed to include a gas outlet opening (14), a back plate (24) coupled to the front cover (12), and a gas outlet barrel (30) having an inlet end, an outlet end (80), and a valve located between the inlet end and the outlet end (80). The apparatus (10) also includes a retention portion located on the back plate (24). The retention portion is configured to engage the barrel (30) adjacent the outlet end (80) to secure the barrel (30) to the back plate (24) and the cover (12) and with the outlet end (80) of the barrel (30) in alignment with the gas outlet opening (14) formed in the front cover (12).
Patent CA-2337900-C (CA)
Inventor: SMITH PAUL D
IPC: G01N1/28
Filed: 1999-07-28
Granted: 2004-05-11
Abstract: Pour procéder à une microdissection par piégeage laser, on place un film polymère de transfert sur un substrat recouvrant de la matière cellulaire visualisée et sélectionnée, issu d'un échantillon pour en être extraite. On active (on fait fondre) le film polymère de transfert sur un volume focal au moyen d'une impulsion suffisamment courte pour que le volume fondu soit confiné au polymère directement irradié. On utilise de courtes impulsions afin de réduire la diffusion thermique dans le polymère environnant qui n'a pas été irradié et afin d'empêcher que ce polymère non irradié soit chauffé et fonde, tout en fournissant suffisamment de chaleur directement absorbée dans le petit volume focal directement irradié par le faisceau laser focalisé. On peut utiliser ce procédé dans la microdissection par piégeage laser avec contact et la microdissection par piégeage laser sans contact précédemment exposées, au moyen soit d'une irradiation par le côté condenseur (le faisceau traverse le polymère avant le tissu) soit d'une épi-irradiation (le laser traverse le tissu avant le polymère). On peut utiliser ce procédé dans une configuration dans laquelle le laser traverse le tissu avant le polymère avec ou sans un substrat rigide supplémentaire. Dans une configuration préférée, ce procédé utilise le confinement inertiel du polymère thermoplastique environnant qui n'a pas fondu (ainsi que le substrat rigide le recouvrant), de façon à pousser l'expansion du polymère fondu dans la cible du tissu recouvert. Grâce à l'utilisation d'impulsions courtes, la matière ciblée et extraite peut présenter un diamètre égal ou inférieur à celui du faisceau d'excitation.
Patent CA-2338323-C (CA)
Title: Capsule en deux parties pour preparations pharmaceutiques destinees aux inhalateurs de medicaments en poudre
Inventor: ECKERT JOSEF
IPC: A61K9/48
Filed: 1999-08-03
Granted: 2009-06-09
Abstract: L'invention concerne des capsules destinées à recevoir des préparations pharmaceutiques pour inhalateurs de médicaments en poudre, qui assurent une bonne protection des médicaments, et des capsules destinées à recevoir des préparations pharmaceutiques pour inhalateurs de médicaments en poudre, qui sont mieux adaptées à l'utilisation avec lesdits inhalateurs. Ces capsules sont constituées de plastiques hydrophobes non hydrosolubles, qui n'influencent sensiblement pas la qualité pharmaceutique des substances qu'ils contiennent, mais qui améliorent la capacité d'utilisation de la capsule remplie du point de vue de sa fonction, de la durée et/ou du lieu géographique de son utilisation, et qui sont avantageux durant les différentes étapes allant de leur fabrication à leur utilisation.
Patent CA-2340476-C (CA)
Title: A method for detecting, recording and deterring the tapping and excavating activities of woodpeckers
Inventor: MCILRAITH ALEXANDER LESLIE
IPC: A01M29/16
Filed: 2001-03-12
Granted: 2005-01-25
Abstract: An apparatus for deterring woodpeckers from tapping on and excavating within a utility pole or the like includes a housing having mounting flanges for direct attachment to the pole so as to receive vibrations therefrom. A  transducer is attached to the mounting wall so as to convert the vibrations preferentially over airborne sounds into signals. A circuit compares the vibrations with a long term average and emits an output in response to detection above a threshold, whereupon the outputs are counted and if the number within a predetermined time exceeds a preset minimum a sound transmitter is actuated for emitting a deterrent sound externally of the housing. A memory contains a plurality of separate audible deterrent sounds including some of the same species and some of predators which act as a deterrent to the woodpeckers and these are selected sequentially and transmitted after a delay to avoid habituation. The power source includes a solar cell charging a battery and to maintain battery power the circuit is arranged to partially power down between detecting periods, to prevent sound actuation at certain times of day and certain times of year and to issue deterrent sounds only once for every set time period.
Patent CA-2344874-C (CA)
Title: Element de garnissage faconne
Inventor: RUKOVENA FRANK
IPC: B01J19/30
Filed: 1999-08-18
Granted: 2005-01-18
Abstract: Un élément de garnissage présentant une pluralité de subdivisions disposées symétriquement à l'intérieur d'un élément de corps cylindrique présente une structure très résistante, résistant aux hautes températures et aux milieux corrosifs et présentant une grande aire de surface.
Patent CA-2345924-C (CA)
Inventor: KIGHTLINGER ADRIAN P
IPC: C08B31/12
Filed: 2001-05-02
Granted: 2006-04-04
Abstract: Disclosed is a method for derivatizing a malto-oligosaccharide. The method includes the steps of providing the malto-oligosaccharide and derivatizing the malto-oligosaccharide in an aqueous medium with a cationic agent to form a derivatized malto-oligosaccharides. Malto-oligosaccharides having a high DS sufficient to render the derivatized product suitable for use as a trash scavenger are attainable in accordance with the present inventive method. Also disclosed are a method for trash scavenging, a process for preparing a paper web, in which anionic trash is scavenged prior to withdrawing a paper web from a pulp furnish; and a paper web prepared in accordance with the present inventive process.
Patent CA-2348148-C (CA)
Title: Applicator with non-twisted core
Inventor: GUERET JEAN-LOUIS
IPC: A46B3/06
Filed: 2001-05-18
Granted: 2005-07-26
Abstract: Applicator has a non-twisted base (20) with going-through bores (21) receiving hairs (22). The support is treated so that the diameter of the bore is reduced and the hairs are maintained in place. Hairs of different lengths and diameters within can be in the same group. The hairs are forming a curl (23), which acts as a product storing device. Independent claims are also included for the conditioning device and the manufacturing process for the conditioning device.
Patent CA-2351009-C (CA)
Title: Coating for metallic implant materials
Inventor: SEWING ANDREAS
IPC: A61L27/32
Filed: 2001-06-19
Granted: 2010-08-03
Abstract: The invention describes a biomimetically produced bone-analogous coating, consisting of an organic and inorganic main constituent, for metallic implant materials of any desired surfaces, it essentially consisting of a collagen matrix mineralized with calcium phosphate, and a process for its preparation.
Patent CA-2364493-C (CA)
Title: Nitrate esters and their use for neurological conditions
Inventor: THATCHER GREGORY R J
IPC: C07F9/09
Filed: 2000-03-15
Granted: 2010-08-31
Abstract: Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effective amount of a therapeutic compound comprising a nitrate ester, or a pharmaceutically acceptable salt or ester thereof.
Patent CA-2367743-C (CA)
Inventor: FUJIKI YUUJI
IPC: F02D41/04
Filed: 2002-01-16
Granted: 2007-01-09
Abstract: There are disclosed a fuel injection control system, a fuel injection control method, and an engine control unit for an internal combustion engine, which are capable of accurately controlling a fuel injection amount according to changes in a valve overlap period due to changes in a cam phase, thereby ensuring proper engine performance. The fuel injection control system for an internal combustion engine which is capable of changing a valve overlap period by changing a cam phase includes an ECU. The ECU calculates a cam phase difference between the present value and the immediately preceding value of the cam phase (amount of change in the valve overlap period), calculates a wall surface temperature of intake ports, and sets a basic fuel injection time period based on an intake pipe absolute pressure and an engine rotational speed. The ECU calculates a final fuel injection time period by correcting the basic fuel injection time period according to the cam phase difference and wall surface temperature of the intake ports.
Patent CA-2371836-C (CA)
Inventor: CHICKERING DONALD E III
IPC: A61K47/12
Filed: 2000-05-25
Granted: 2006-01-31
Abstract: Drugs, especially low aqueous solubility drugs, are provided in a porous matrix form, preferably microparticles, which enhances dissolution of the dr ug in aqueous media. The drug matrices preferably are made using a process that includes (i) dissolving a drug, preferably a drug having low aqueous solubility, in a volatile solvent to form a drug solution, (ii) combining at least one pore forming agent with the drug solution to form an emulsion, suspension, or second solutions, and (iii) removing the volatile solvent and pore forming agent from the emulsion, suspension, or second solution to yiel d the porous matrix of drug. The pore forming agent can be either a volatile liquid that is immiscible with the drug solvent or a volatile solid compound , preferably a volatile salt. In a preferred embodiment, spray drying is used to remove the solvents and the pore forming agent. The resulting porous matrix has a faster rate of dissolution following administration to a patient, as compared to non-porous matrix forms of the drug. In a preferred embodiment, microparticles of the porous drug matrix are reconstituted with an aqueous medium and administered parenterally, or processed using standard techniques into tablets or capsules for oral admisnistration. Paclitaxel or docetaxel c an be provided in aporous matrix form, which allows the drug to be formulated without solubilizing agents and administered as a bolus. rocessed using standard techniques into tablets or capsules for oral administration. Paclitaxel or docetaxel can be provided in a porous matrix form, which allow s the drug to be formulated without solubilizing agents and administered as a bolus.
Patent CA-2372063-C (CA)
Inventor: GALLI FREDERIC
IPC: A61P25/24
Filed: 2000-03-01
Granted: 2011-01-11
Abstract: Composés de formule générale (I) dans laquelle R¿1? représente un atome d'hydrogène, un groupe alkyle, phénylalkyle, phénylhydroxyalkyle, furanylalkyle ou furanylhydroxyalkyle, R¿2? représente soit un atome d'hydrogène ou d'halogène ou un groupe trifluorométhyle, cyano, hydroxy, nitro, acétyle, alkyle, alcoxy, amino de formule générale NR¿4?R¿5? dans laquelle R¿4? et R¿5? représentent chacun un atome d'hydrogène ou un groupe alkyle ou forment, avec l'atome d'azote qui les porte, un cycle en C¿4?-C¿7?, soit un groupe phényle ou naphtyle éventuellement substitué par un atome d'halogène ou un groupe trifluorométhyle, trifluorométhoxy, cyano, hydroxy, nitro, acétyle, alkyle, alcoxy, ou méthylènedioxy, et R¿3? représente un atome d'hydrogène ou d'halogène ou un groupe alkyle.
Patent CA-2376648-C (CA)
Title: Generateur de torsion
Inventor: SOROCHINSKY ALEXANDER PANTELEE
IPC: C02F3/00
Filed: 2001-04-10
Granted: 2007-07-03
Abstract: L'invention concerne un générateur de torsion composé d'un boîtier (1), dans lequel au moins un canal (2) est formé, dont l'entrée est placée à proximité de la périphérie du boîtier (1). L'axe longitudinal du canal (2) passe sur la courbe logarithmique, dans laquelle la séquence mathématique de construction des coordonnées est différente pour chaque partie de la courbe. La sortie du canal (2) communique avec la caméra (3), formée à l'intérieur du boîtier (1) et est reliée au conduit sortant (4). L'entrée du canal (2) se trouve en position tangentielle par rapport au boîtier et la sortie en position axiale, par rapport à ce même boîtier (1).
Patent CA-2378118-C (CA)
Inventor: HOLL BERND
IPC: E01C23/12
Filed: 2000-07-14
Granted: 2006-09-05
Abstract: L'invention concerne un engin de construction comportant un châssis (2) dans lequel un cylindre de fraisage (18) est monté rotatif. Ledit cylindre de fraisage (18) comporte un corps de base cylindrique (19) entraîné par un dispositif d'entraînement de cylindre de fraisage (11 à 15) par l'intermédiaire d'une unité de transmission (32) et un tube de fraisage (25) fixé de manière échangeable, pouvant être poussé dans le sens coaxial sur le corps de base cylindrique (19). Le tube de fraisage (25) porte des outils de coupe sur sa surface d'enveloppe extérieure (46). Il est prévu que le tube de fraisage (25) présente des éléments de fixation (28) faisant saillie dans le sens radial de la surface d'enveloppe intérieure (44) et destinés à fixer le tube de fraisage (25) bloqué en rotation sur le corps de base cylindrique (19) ou sur une partie liée au corps de base cylindrique (19).
Patent CA-2380308-C (CA)
Inventor: SPEED DAVID
IPC: E21B21/06
Filed: 2000-11-15
Granted: 2005-05-24
Abstract: A method and apparatus for treating pressurized drilling fluid returns from a well having a returns outlet. The method comprises the steps of providing a primary separator for selectively separating solid, liquid and gas components of the drilling fluid returns where the primary separator has an input for introducing drilling fluid returns thereto; providing a secondary separator for selectively separating at least a portion of a gas component in the drilling fluid returns where the secondary separator has an input for introducing drilling fluid returns thereto; connecting the input of the primary separator and the input of the secondary separator to the returns outlet of the well such that the input of the secondary separator is connected to the well returns outlet upstream of the input of the primary separator; providing a control to regulate the flow of drilling fluid returns through the input of the primary and secondary separators; monitoring the flow of the gas component of the drilling fluid returns expelled from the primary separator; and, in response to changes in the flow of gas expelled from the primary separator, operating the control to regulate the flow of drilling fluid returns through the primary and secondary separators to maintain the flow of gas expelled from the primary separator within predetermined parameters.
Patent CA-2383779-C (CA)
Title: N-(indolecarbonyl)piperazine derivatives
Inventor: BOTTCHER HENNING
IPC: A61P25/16
Filed: 2000-07-07
Granted: 2011-03-29
Abstract: Compounds of the formula I   (see formula I) in which R1, R2, R4 and R5 have the meanings indicated in Claim 1, are potent 5-HT2A antagonists and are suitable for the treatment of psychoses, schizophrenia, depression, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease, eating disorders such as bulimia, nervous anorexia, premenstrual syndrome and/or for positively affecting compulsive behaviour (obsessive-compulsive disorder, OCD).
Patent CA-2390574-C (CA)
Title: Multi-pole circuit breaker with parallel current
Inventor: BEATTY WILLIAM ELLSWORTH
IPC: H01H71/10
Filed: 2002-06-13
Granted: 2012-01-03
Abstract: A circuit breaker includes a plurality of poles that are connected with one another in parallel, and additionally includes a mutual connection connecting the poles with one another to isolate the trip units associated with the poles from any imbalance in the current flowing through the poles. Each pole includes a first conductor structured to be connected with a power source, a second conductor structured to be connected with an electrical load, and a pair of separable contacts that disconnectably connect the first conductor with the second conductor. The trip unit of each pole is configured to measure the current flowing through a given point of the second conductor, and the mutual connection connects the second conductors together at a connection point, the connection point of each second conductor being between the separable contacts and the given point.
Patent CA-2393682-C (CA)
Inventor: SKOV SOREN
IPC: C07K5/10
Filed: 2000-12-06
Granted: 2012-01-31
Abstract: L'invention concerne des depsipeptides et leurs congénères ayant la structure (I) dans laquelle <i>m</i>, <i>n</i>, <i>p</i>, <i>q</i>, X, R1, R2 et R3 ont la notation ci-définie. Ces composés, notamment FR901228, présentent une activité, par exemple, en tant qu'immunodépresseurs, et également dans la prévention ou le traitement de patients souffrant ou présentant un risque de souffrir de maladies inflammatoires, auto-immunes ou liées au système immun notamment une maladie du greffon contre l'hôte et l'amélioration de la survie du greffon/des tissus après transplantation. L'invention concerne également des méthodes d'inhibition de l'activation, la prolifération des lymphocytes, et/ou de suppression des sécrétions d'IL-2.
Patent CA-2394554-C (CA)
Inventor: EARLE WALTER R
IPC: B65D83/38
Filed: 2002-07-24
Granted: 2006-11-07
Abstract: A dispenser apparatus for ultrasound gel comprises a cylindrical body having a closed first end and a dispensing opening at the other end. There is an inlet opening near the first end in fluid communication with a source of pressurized ultrasound gel. A plunger is secured to a shaft near its first end; and there is a valve element at the second end of the shaft, adapted to close the dispensing opening when the shaft is in a first, at rest position, and to permit a dispensing operation when the shaft is in a second, dispensing position. The plunger has at least one passageway formed through its thickness, extending towards a second face. A plunger return spring acts against the second face of the plunger, so as to urge it towards the rest position. A freely moving sealing plate covers the passageway, and is mounted for longitudinal movement along the shaft; and has a return spring to urge it towards the second face of the plunger. The plunger covers the inlet opening when in its first position. A trigger moves the shaft and the plunger against the return springs, and the valve element is moved into the dispensing position away from the dispensing opening.  Chambers above and below the plunger are always filled with gel.
Patent CA-2397821-C (CA)
Inventor: BERGERON JULES
IPC: C23C18/00
Filed: 2001-02-09
Granted: 2007-02-06
Abstract: A method of treating a carbonaceous cell component of an electrolyte cell for the production of aluminum, to impart protection against deterioration during operation of the cell. A liquid suspension of a refractory material dispersed in a lignosulfonate binder solution is prepared and applied as a protective coating to the surface of carbonaceous cell components and allowed to dry.
Patent CA-2398132-C (CA)
Title: Mobile elevator working and load-lifting platform
Inventor: JULIEN ROMAIN
IPC: B66F11/04
Filed: 2002-08-13
Granted: 2011-07-19
Abstract: A ground-movable load-lifting vehicle for lifting a load over ground. The vehicle comprises a platform bed, a ground-movable carriage, and an extendible scissor linkage assembly supporting the platform bed spacedly over the carriage. A hydraulic ram system enables power extension of the scissor linkage assembly against the bias of a load supported by said platform bed. The carriage further includes peripheral ground-engageable pivotal casters, rotatably mounted to the carriage in spaced apart fashion, and a pair of ground-engageable drive wheel assemblies, mounted for relative movement to a central portion of the carriage, wherein the drive wheel assemblies provide omnidirectional displacement capability for this load-lifting vehicle. A power unit, controlled by an electronic circuit, powers both the hydraulic rams of the scissor linkage assembly and the drive wheel assemblies.