baber/WOPTO huggingface dataset:
Patent RU-2710370-C2 (RU)
Title: Pharmaceutical compositions containing celecoxib and tramadol
Inventor: KIM JUNG JU
IPC: A61K31/135
Filed: 2016-06-29
Granted: 2019-12-26
Abstract: FIELD: medicine; pharmaceuticals. 
     SUBSTANCE: invention refers to anaesthetic. Pharmaceutical composition is a solid combined composition for oral administration and contains: a first compartment containing celecoxib, 0.1–20 wt. % of a water-soluble polymer and a surfactant, wherein the water-soluble polymer is selected from hydroxypropyl cellulose, hydroxypropyl-methylcellulose and a copolymer of vinylpyrrolidone, vinyl acetate or a combination thereof, and 10–50 wt. % of saccharide, where the saccharide is selected from mannitol, maltitol, lactitol, ribit, inositol, xylitol, maltotritol, glucose or a combination thereof; a second compartment containing tramadol, 1–60 wt. % of water-insoluble polymer and a wax-like lipid, where water-insoluble polymer is selected from cellulose-based polymers or a combination thereof, and where the wax-like lipid is selected from glycerol stearate, glycerol-behenate, glycerol palmitostearate, fatty acid macroglyceride, diethylene glycol monoethyl ether, glyceryl monocaprylate, hydrogenated castor oil or a combination thereof. 
     EFFECT: invention provides optimized release patterns of the respective drugs for manifesting the synergetic effects of the respective drugs in anaesthesia. 
     1 cl, 13 dwg, 26 tbl, 3 ex
Patent RU-2729159-C2 (RU)
Title: Сельскохозяйственная уборочная машина с движущейся в боковом направлении скатной зерновой доской
Inventor: DYUKEN FRANK R ZH
IPC: A01F12/32
Filed: 2016-08-26
Granted: 2020-08-04
Abstract: Изобретения относятся к сельскому хозяйству. Сельскохозяйственная уборочная машина содержит: шасси, систему обмолота и разделения, содержащую по меньшей мере один обмолачивающий ротор, скатную зерновую доску, которая принимает растительный материал из указанной системы обмолота и разделения, при этом указанная скатная зерновая доска выполнена с возможностью качания в продольном направлении и боковом направлении, и систему очистки, которая содержит верхнее решето и нижнее решето выполненные с возможностью качания в продольном направлении и боковом направлении, при этом указанное нижнее решето выполнено с возможностью качания в продольном направлении и в боковом направлении в противофазе с указанной скатной зерновой доской, указанное верхнее решето выполнено с возможностью качания в боковом направлении с совпадением по фазе с указанной скатной зерновой доской, и указанный обмолачивающий ротор установлен в продольном направлении указанной сельскохозяйственной уборочной машины. Способ управления транспортировкой растительного материала через сельскохозяйственную уборочную машину, имеющую шасси. Изобретения позволяют избежать нежелательных вибраций системы обмолота и системы очистки. 2 н. и 14 з.п. ф-лы, 15 ил.
Patent RU-2754939-C2 (RU)
Inventor: SCOTTO ANDREA
IPC: B01J2/04
Filed: 2018-04-30
Granted: 2021-09-08
Abstract: Изобретение относится к способу отверждения химического продукта в форме плава для получения твердого продукта в виде прилов или гранул. В частности, изобретение относится к сфере производства твердой мочевины. В заявке описан способ отверждения химического продукта, имеющего форму плава, при осуществлении которого: подвергают первый поток химического продукта приллированию с получением прилов различного диаметра; подают эти прилы в сортировочное устройство, в котором они разделяются по диаметру на по меньшей мере первую фракцию и вторую фракцию, причем средний диаметр прилов первой фракции меньше среднего диаметра прилов второй фракции, подвергают второй поток химического продукта и первую фракцию прилов гранулированию с получением гранул. Изобретение позволяет получить твердый продукт с улучшенными характеристиками в части размеров и механической прочности по сравнению с продуктом, получаемым обычными способами. 3 н. и 3 з.п. ф-лы, 1 ил.
Patent RU-2753027-C2 (RU)
Title: Reactor for conducting exothermic equilibrium reactions
Inventor: KASTILLO-VELTER FRANK
IPC: B01J8/06
Filed: 2018-04-26
Granted: 2021-08-11
Abstract: FIELD: engineering. 
     SUBSTANCE: proposed is a reactor for conducting exothermic equilibrium reactions, wherein a gaseous feed mixture is at least partially converted by means of a solid catalyst into a finished mixture containing at least one liquid reaction product condensed at a pressure in the reactor and temperatures below the temperature in the reactor, containing at least two reaction chambers connected consequently, fluidly communicating with each other and located in a common reactor shell, wherein each reaction chamber comprises the following consequently connected units in fluid communication with each other: (a) a preheating area suitable for heating a feed mixture or a gaseous product stream from an upstream reaction chamber, wherein use of the preheating area is optional in the first reaction chamber in the direction of the gaseous feed mixture stream, (b) at least one reaction area containing a catalyst, active with respect to the conducted exothermic equilibrium reaction, and a cooling apparatus in heat exchange communication with the catalyst, (c) at least one cooling area containing a cooling apparatus suitable for cooling a partially converted gaseous product stream filled with a condensable reaction product and outflowing from the reaction area to a temperature below the dew point of the gas, (d) a precipitation area containing a gas-liquid phase separation apparatus intended to separate the product stream outflowing from the cooling area into a stream of gaseous product freed from condensate and a condensate stream containing a liquid reaction product, (e) a pipeline tool for discharge of the condensate stream containing a liquid reaction product from the reactor and optionally a tool for supplying a condensate stream to an apparatus for processing a reaction product, (f) a tool for diverting the gaseous product stream freed from the condensate, and a tool for supplying the gaseous product stream to a downstream reaction chamber and/or a tool for diverting the gaseous product stream from the reactor. Also proposed is an application of the described reactor for producing methanol by converting feed synthesis gas containing carbon dioxide. 
     EFFECT: technical result is determination of a reactor providing, namely, a high degree of conversion based on the target products of an exothermic reaction per pass in the reactor and a possibility of reconfiguring and therefore optimising reaction conditions along the longitudinal coordinate of the reactor, thereby decreasing the recirculation coefficient to lower values. 
     16 cl, 7 dwg, 5 tbl, 2 ex
Patent RU-2766263-C2 (RU)
Inventor: EJKELKAMP MARKUS FRANTSISKUS
IPC: B26B19/38
Filed: 2018-09-24
Granted: 2022-02-10
Abstract: Изобретение относится к области устройств для срезания волос. Режущий блок для устройства для срезания волос содержит держатель лезвия с режущим лезвием и защитный элемент. Защитный элемент включает обращенную к лезвию поверхность, плоскую защитную контактную поверхность и пазы для приема волос. Удлинитель защитного элемента явлется отдельным от защитного элемента. Удлинитель защитного элемента содержит плоскую удлинительную контактную поверхность. Обращенная к лезвию поверхность и защитная контактная поверхность сходятся к кончику защитного элемента. Удлинительная контактная поверхность расположена позади защитной контактной поверхности относительно направления резания. Удлинительная контактная поверхность имеет поперечную протяженность вдоль оси, перпендикулярной направлению резания. Вдоль направления резания между защитной контактной поверхностью и поперечным участком удлинительной контактной поверхности имеется зазор. Изобретение также включает устройство для срезания волос. Техническим результатом является улучшение качества бритья. 2 н. и 11 з.п. ф-лы, 11 ил.
Patent UA-73076-C2 (UA)
Title: Aqueous aerosol preparations containing biologically active macromolecules and method for their manufacture
IPC: A61K9/12
Filed: 1998-07-31
Abstract: The invention relates to aqueous aerosol preparations containing biologically active macromolecules for producing inhalable aerosols without propellant gases.
Patent UA-73731-C2 (UA)
Title: v-CARBOXYARYL SUBSTITUTED DYPHENYL UREA AS RAF-KINASE INHIBITOR
IPC: A61K31/24
Filed: 2000-01-12
Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
Patent UA-55059-C2 (UA)
Title: Method for isolating biologically active compounds from propolis providing for complete utilization of raw material
Inventor: TYKHONOV OLEKSANDR IVANOVYCH
IPC: A61K35/64
Filed: 2002-06-19
Abstract: The method for isolating the biologically active compounds from propolis providing for complete utilization of the raw material is based on employing the water and the ethanol as the solvents. First the raw material is subjected to the treatment with the heated water. Three fractions, namely the wax, the aqueous extract and the non-extracted material are obtained. Then upon addition of the solubilizer to the aqueous product the hydrophilic substances are obtained while upon addition of the non-polar solvent to the non-extracted residue the hydrophobic substances are produced.
Patent UA-75882-C2 (UA)
Title: Method for surface treatment of implants and titanium implant
IPC: A61L27/00
Filed: 2001-09-14
Abstract: Separate and successive treatment in carried on a portion of the implant using three acids: hydrofluoric, sulfuric and hydrochloric acids. An evenly distributed roughness with a broad relief is thus obtained. Said surface is then contacted with a plasma rich in growth factors.
Patent UA-60726-C2 (UA)
Title: Twisted yarn
Inventor: BEREZNENKO MYKOLA PETROVYCH
IPC: D02G3/26
Filed: 2003-02-11
Abstract: The twisted yarn includes the roving and the spun ordinary thread with content of natural fiber with prescribed twisting of the last one. As natural fiber there are chosen cottonized hemp or cottonized flax fibers at content of those 10-80 % of the quantity of the fiber mix.
Patent UA-85366-C2 (UA)
Title: Viral polymerase inhibitors
Inventor: BEAULIEU PIERRE LOUIS
IPC: A23L21/10
Filed: 2002-07-18
Abstract: An isomer, enantiomer, diastereoisomer or tautomer of a compound, represented by formula I: wherein: A is 0, S, NR', or CR, wherein Ris defined herein; represents either a single or a double bond;Ris selected from: H, halogen, R, OR, SR, СООR,SON(R), N(R), СОN(R,NRС(O)Ror NRC(O)NRwherein Rand each Ris defined herein; В is NRor CR, with the proviso that one of A or В is either CRor CR, wherein Ris defined herein; К is N or CR, wherein R- is defined herein; L is N or CR, wherein Rhas the same definition as R; M is N or CR, wherein Rhas the same definition as R; Yis 0 or S; Z is N(R)Ror OR, wherein Ris H or alkyi or NRRwherein Rand Rare defined herein; and Ris H, alkyi, cycloalkyi, alkenyl, Het, alkyl-aryl, alkyl-Het;or R' is wherein Rand Rand Q are as defined herein; Yis 0 or S;Ris H, (Calkyi), (C)cycloalkyl or (C)alkyl-(C)cycloalkyI, aryl, Het, (C)alkyl-aryl or (Ci.6)alkyl-Het, all of which optionally substituted with R;or Ris covalently bonded to either of Ror Rto form a 5- or 6-membered heterocycle; a salt or a derivative thereof, as an inhibitor of HCV NS5B polymerase.
Patent UA-78221-C2 (UA)
Title: Pyrimidine derivatives inhibiting hiv
Inventor: GUILLEMONT JEROME EMIL GEORGE
IPC: C07D233/96
Filed: 2002-09-08
Abstract: EMBED ISISServer , (I) This invention concerns HIV replication inhibitors of formula (I) the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, wherein the ring containing -a1=a2-a3=a4- and -b1=b2-b3=b4- represents phenyl. pyridyl, pyrimidinyl, pirazinyl, pyridazinyl; n is 0 to 5; m is 1 to 4; R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alkyloxycarbonyl, substituted C1-6alkyl, C1-6alkylcarbonyl; R2 is hydroxy, halo, optionally substituted C1-6alkyl, C3-7cycloalkyl, optionally substituted C2-6alkenyl, optionally substituted C2-6alkynyl, C1-6alkyloxy, C1-6alkyloxycarbonyl, carboxyl, cyano, nitro, amino, mono- or di(C1-6alkyl)amino, polyhalomethyl, polyhalomelhyloxy, polyhalomcthylthio, -S(=O)pR6, -NH-S(=O)pR6, -C=(O)R6, -NHC(=O)H -C(=O)NHNN?2?, -NHC(=O)R6, -С(=NН)R6 or a 5-membered heterocycle; X1 is -NR5-, -NH-NH, N=N, -O-, C(=O)-, C1-4alkanediyl, -CHOH , -S-, -S(=O)p-, -X2-C1-4alkanediyl- or C1-4alkanediyl –X2-; R3 is NHR13; і NR13R14; -C(=O)-NHR13; -C(=O)-NR13R14; -C(=O)-R15; -CH=N-NH-C(=O)-R16; substituted C1-6alkyl; optionally substituted C1-6alkyloxyC1-6alkyl; substituted C2-6alkenyl; substituted C2-6alkynyl; C1-6alkyl substituted with hydroxy and a second substituent; -C(=N-O-R8)-C1-4alkyI; R7; or –X3-R7; R4 is halo, hydroxy, C1-6alkyl, C3-7cycloalkyl, C1-6alkyloxy, cyano, nitro, po1yhaloC1-6alkyl, polyhaloC1-6alkyloxy, aminocarbonyl, C1-6alkyloxycarbonyl, C1-6alkylcarhonyl, formyl, amino, mono- or di(C1-6alkyl)amino; their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.
Patent UA-82861-C2 (UA)
Title: Shearing machine for transversally dividing heavy steel plate by means of eccentric drive
Inventor: HEITZE GERHARD
IPC: B23D33/02
Filed: 2003-12-15
Abstract: The invention relates to a shearing machine for transversally dividing especially a heavy steel plate, said shearing machine comprising an upper blade (3) which carries out a rolling cutting movement by means of an eccentric drive (8) and is held in a blade carrier (1). and a lower blade (4) which is arranged in the frame of the shearing machine (2) in a fixed manner, the upper blade carrier (1) being displaceably connected to a stand (6) of the shearing machine frame (2) by means of an articulated guiding element (5). A device for the clocked advance of a pre-determinable length of the steel plate is associated with the shearing machine, especially in the form of at least one driving element. The aim of the invention is to improve the stability of the shearing machine and thus the quality of the cut. To this end, the shearing machine is arranged between lateral stands (6, 6') of the shearing machine frame (2) which is closed by an upper traverse (7) and a lower traverse (7'). The eccentric drive (8, 8') of the upper blade (3) is arranged in the upper region of said frame, and bearings (10, 10') and driving bodies (11) of lower driving rolls (12. 12') are arranged in the lower region of said frame, in addition to a lower blade table (9) which is anchored between the stands (6, 6').
Patent UA-86374-C2 (UA)
Title: Rejector filter
Inventor: DOLHIN VOLODYMYR PROHOROVYCH
IPC: H03H17/04
Filed: 2005-12-30
Abstract: The invention relates to radio filtering systems and communication quality control. The said filter may be used in compensatory system of automatic control systems. A rejector filter is based on recurrent description of filter reaction of automatic control systems with operator fractional rational function of 2-th order. The filter consists of in series connected modules each of which comprises in series connected: a multiplier, an adder and a delay element. Modules are connected to multiplier which comprises inputs for attenuation and rejection frequency. Multipliers outputs are connected to adders. The technical result of the invention is growth of stability and accuracy of recurrent rejector filter.
Patent UA-91008-C2 (UA)
Title: Agent for prevention and treatment of acute hepatitis in young pigs
Inventor: ANTONENKO PETRO PAVLOVYCH
IPC: A61K31/045
Filed: 2006-05-26
Abstract: The invention relates to veterinary medicine and concerns an agent for prevention and treatment of acute hepatitis in young pigs which comprises a mixture of aqueous infusions of blind weed herb, yellow everlasting herb, common tansy flowers, 40% alcoholic infusions of peppermint herb, setwell root, belladonna leaves and magnesium sulfate, sodium salicylate, hexamethylenetetramine, glycerine, alcohol and distilled water.
Patent UA-83938-C2 (UA)
Title: Method for treatment of heterogeneous by permeability productive oil fields
Inventor: KISIL IHOR STEPANOVYCH
IPC: E21B43/22
Filed: 2006-12-20
Abstract: Method for treatment of heterogeneous by permeability productive oil fields includes sequential injection of water solutions of polymer, surface-active substance (SAS) and water. Before treatment one determines hydraulic links between water-supercharge and production wells, permeability and power of seam, contour of covering with water solution of SAS and needed quantity of technological liquids through injection, in sequence, to all water-supercharge wells of oil-bearing productive field affected with group pumping station of system of support of stratal pressure water solution of indicator reagent. One uses water solution of polyacrylamide and as water solution of SAS – 1-2 % solution of Ripox-6. To all water-supercharge wells one injects in first calculated volumes of water solution of polyacrylamide, and then water solution of Ripox-6 with respective concentration, water supercharge wells are soaked after each of injection processes for flow of respective reactions in porous of oil-bearing field, and then water is injected. Increase of end coefficient of oil liberation of field is provided at decrease of power consumption.
Patent UA-85427-C2 (UA)
Title: railroad tank car
Inventor: BUBNOV VALERII MYKHAILOVYCH
IPC: B61F1/00
Filed: 2007-02-12
Abstract: The invention relates to rail transport. A railroad tank car contains a boiler, which includes two extreme and one middle cowling with drain branch pipe located on the central axis, and a bottom. The boiler is fastened by frames, it is installed by means of supporting units, which include supporting sheets, stringers, which are connected to longitudinal sheet cover plates welded to the boiler. Each stringer is made, at least, from three parts - two short and one long part. Between it and extreme center sill a flat insert is installed, lower profile thereof provides smooth passage from end center sill to the stringer. The lower part of the connection of insert with the stringers and extreme center sill is closed with a plate fastened from below by stiffening ribs installed in one plane with combinable parts. At junction of flat insert with stringer an edge is installed, which is connected by lower face with said plate, and by the face side - with cover plate of boiler. Between the boiler and each extreme center sill a rectangular frame is installed, with upper edge repeating the profile of the boiler. The technical result is in reduction of the mass of boiler with simultaneous reduction of the center of gravity of the railroad tank car and increase of its durability.
Patent UA-85104-C2 (UA)
Title: Method for obtaining of lipophilic complex from the hips
Inventor: DEMIANENKO VIKTOR HRYHOROVYCH
IPC: A61P29/00
Filed: 2007-02-14
Abstract: The invention relates to a method for obtaining of lipophilic complex from the hips by extraction with the liquefied gas under the pressure with the subsequent extractant removal, at that the hips are used in the atomizated form with the particle size of 0.355- with humidity of 0-10 %, mainly 5-7 %, difluorochloromethane is used as the extractant and the extraction is carried during at least 30 minutes with the permanent discharge of the prepared extract, carrying out extraction so that during the first 10 minutes the specific consumption of extractant is 200-250 ml/min. per of raw material; during the rest of the time – 50-70 ml/min. per of raw material.
Patent UA-96407-C2 (UA)
Title: Method of stabilizing copper (ii) hydroxide, fungicidal or bactericidal composition comprising stabilized copper (ii) hydroxide
Inventor: OBERHOLZER MATTHEW RICHARD
IPC: A01N59/16
Filed: 2005-08-30
Abstract: Disclosed is a method of stabilizing copper (II) hydroxide, the method comprising the sequential steps of: (a) combining copper (II) hydroxide, a water-soluble phosphate and water to form a mixture; and (b) drying the mixture. Also disclosed is stabilized copper (II) hydroxide prepared according to said method and a composition comprising stabilized copper (II) hydroxide prepared according to said method and at least one of a surfactant, a solid diluent or a liquid diluent.
Patent UA-87022-C2 (UA)
Title: Two-piece capsule comprising a preliminary closure for accommodating pharmaceutical preparations for powder inhalers
Inventor: KUEHN TORSTEN
IPC: A61K9/48
Filed: 2006-01-06
Abstract: The invention relates to capsules for accommodating pharmaceutical preparations for powder inhalers having increased safety regarding the medicament as well as capsules for pharmaceutical preparations for power inhalers featuring an improved adjustment to the use in powder inhalers. Said capsules are made of non-hydrosoluble, hydrophobic plastics which do not substantially influence the pharmaceutical quality of the substances contained therein while improving the usability of the filled capsule regarding the function thereof, the duration of the use, and/or the geographic location where the same can be used. Furthermore, the inventive capsules are advantageous in different stages, from the production to the use thereof.
Patent UA-98292-C2 (UA)
Title: 5-phenyl-pentanoic acid derivatives as matrix metalloproteinase inhibitors for the treatment of asthma and other diseases
Inventor: PALLE VENKATA
IPC: C07D213/64
Filed: 2006-02-21
Abstract: The present invention relates to C ompounds having the structure of Formula I: wherein n is an integer from 1 to 5; R4 is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, alkoxy, aryloxy, alkeny-loxy or alkynyloxy; R2 is alkenyl, allcynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, NR4R5, -NHC(=Y)R4, - NHC(=Y)NR5RX, -NHC(=O)OR4, -NHSO2R4, C(=Y)NR4R5, C(=O)OR6 [wherein Y is oxygen or sulphur], OR5, -O(C=O)NR4R5, O-acyl, S(O)mR4, -SO2N(R4)2, cyano, amidino or guanidino [wherein R4 is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl and m is an integer 0-2; R5 is hydrogen or R4, Rx is R4 or -SO2N(R4)2 and Rs is hydrogen, alkyl, cycloalkyl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl]; R3 is hydrogen, fluorine, alkyl, cycloalkylalkyl or aralkyl; A is OH, OR4, -OC(=O)NR4R5, O-acyl, NH2, NR4R5, -NHC(=Y)R4, -NHC(=Y)NR5RX, - NHC(=O)OR4, -NHSO2R4, and to processes for the synthesis of the same. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by over-expression and over-activation of an matrix metalloproteinase, using the compounds.
Patent UA-93523-C2 (UA)
Title: urn:schemas-microsoft-com:office:smarttagsBALL SCREW DRIVEHAVING OVERLOAD CLUTCH
Inventor: ABRAHAM SIMON
IPC: F16H25/20
Filed: 2006-11-01
Abstract: According to the invention, a ball screw drive (3) having a housing in which a spindle nut (9) is arranged on a ball screw spindle (7), having an overload clutch (10) which disengages when a force acting on the ball screw spindle (7) reaches a release force, having a pretensioning device (13) which, with at least one adjusting member (5), can be set to a pretensioning force and acts on the overload clutch (10), and having a moveable pressure element (11) on which the pretensioning device (13) can engage in order to transmit the pretensioning force to the overload clutch (10), is characterized in that the housing (3) is of single-part design and the pressure element (11) is arranged so as to slide on a housing face (3a, 3b) and on a peripheral face (9a) of the spindle nut (9).