baber/WOPTO huggingface dataset:
Patent WO-2020212361-A1 (WO)
Inventor: LIMER ADAM
IPC: A61K9/00
Filed: 2020-04-14
Abstract: A composition comprising polysaccharide and calcium carbonate for use in a method to decrease relative dentin abrasivity (RDA) without reducing cleaning efficiency.
Patent WO-2020229447-A1 (WO)
Inventor: SUBRATTY SHAMEER
IPC: G01N30/60
Filed: 2020-05-12
Abstract: A chromatography device (1; 101) comprising: - at least one chromatography material unit (3), wherein said chromatography material unit comprises a convection-based chromatography material; - at least one fluid distribution system (7) which is configured to distribute fluid into and out from the at least one chromatography material unit (3); - an inlet (15); - at least one inlet fluid channel (17a, 17b) connecting the inlet (15) with each chromatography material unit (3) via the fluid distribution system (7); - an outlet (19); and - at least one outlet fluid channel (21) connecting the outlet (19) with each chromatography material unit (3) via the fluid distribution system (7), wherein at least some parts of said chromatography device (1; 101) are overmolded and sealed together by plastic or elastomer leaving at least the inlet (15) and the outlet (19) open.
Patent WO-2020240040-A1 (WO)
Inventor: KAPS CHRISTIAN
IPC: C12N5/077
Filed: 2020-06-02
Abstract: The present invention relates to a method for propagating or enriching cartilage cells and providing spheroids thereof, wherein the spheroids are useful for an autologous chondrocyte implantation (ACI) product. Hence, the invention in particular relates to the production of spheroids from articular cartilage and use thereof.
Patent WO-2021121676-A1 (WO)
Inventor: MATOUSEK VIT
IPC: G06F11/36
Filed: 2020-06-29
Abstract: Problem Software testing is an important yet costly part of state-of-the-art software projects. Prior-art statistical or machine learning (ML) approaches allow for some reduction in test effort by indicating - before their execution - those test cases in a test suite which are likely to fail. Still, test execution ties up a significant part of development resources. The invention aims to free or optimize use of these resources. Solution Computer-implemented method of predicting status of a testcase of a software maintained by means of a code repository, characterized in, for each execution of the testcase, logging the status as a multi-valued attribute such as "pass" or "fail", for each two chronologically adjacent executions, retrieving from the repository any changeset committed interjacently and observing correlation between the changeset and transition in status between the two executions, such as from "pass" to "fail", "fail" to "pass", "fail" to "fail", or "pass" to "pass", based on the observed correlations, building a training dataset from input vectors representing the changesets, each input vector being labelled with the correlating transition, fitting a statistical classification model on the training dataset, and, by means of the model, predicting the transition resulting from committing a given further changeset to the repository.
Patent WO-2021001522-A1 (WO)
Inventor: METZNER HUBERT
IPC: A61K38/37
Filed: 2020-07-03
Abstract: The present invention relates to the use of a polypeptide comprising a truncated von Willebrand Factor (VWF) for increasing the in vitro stability of coagulation factor VIII (FVIII) in a composition comprising said FVIII and said polypeptide, wherein the molar ratio of the polypeptide to the FVIII in the composition is greater than 20.
Patent WO-2021005024-A1 (WO)
Inventor: WIESEND JOHANNES
IPC: H01L21/48
Filed: 2020-07-07
Abstract: Verfahren zur Herstellung eines Kühlelements (1) für ein elektrisches oder elektronisches Bauteil, insbesondere ein Halbleiterelement, wobei das gefertigte Kühlelement (1) ein Kühlfluidkanalsystem aufweist, durch das im Betrieb ein Kühlfluid durchleitbar ist, umfassend - Bereitstellen mindestens einer ersten Metallschicht (11), - Realisieren mindestens einer Ausnehmungen (21, 22) in der mindestens einen, ersten Metallschicht (11), und - Ausbilden zumindest eines Teilabschnitts des Kühlfluidkanalsystem mittels der mindestens einen Ausnehmung (21, 22), wobei mindestens ein erster Teil (21) der mindestens einen Ausnehmung (21, 22) in der mindestens ersten Metallschicht (11) durch Erodieren, insbesondere Funkenerodieren, realisiert wird.
Patent WO-2021018522-A1 (WO)
Title: A voltage clamp circuit
Inventor: KLEIN MARKUS
IPC: H02M1/34
Filed: 2020-07-07
Abstract: The voltage clamp circuit (10) as seen in figure (2), is adapted to clamp, voltage of an energy limited signal. The voltage clamp circuit (10) comprising a semiconductor component (12) electrically connected to a source (14), a capacitive component (16) electrically connected between one end of the semiconductor component (12) and a ground terminal and a precharging circuit electrically connected between one of said semiconductor component and a voltage supply line.
Patent WO-2021019033-A1 (WO)
Inventor: SOSTELLY ALEXANDRE ANTOINE BERNARD
IPC: A61K39/00
Filed: 2020-07-30
Abstract: The present invention relates to a dosage and administration regimen of anti-C5 antibodies, particularly of the anti-C5 antibody Crovalimab, for use in a method of treating or preventing C5-related disease in a subject, including paroxysmal nocturnal hemoglobinuria (PNH). The dosage and treatment regimen of the present invention include the administration of an anti-C5 antibody, preferably of the anti-C5 antibody Crovalimab, with loading doses followed by the administration of (a) maintenance dose(s) of the anti-C5 antibody to the subject, wherein the initial administered loading dose is intravenously given to the subject and the remaining loading and maintenance doses are subcutaneously administered in a lower dosage as the intravenously administered loading dose.
Patent WO-2021032496-A1 (WO)
Title: Methods, apparatus and machine-readable media relating to machine-learning in a communication network
Inventor: NORRMAN KARL
IPC: G06N3/08
Filed: 2020-08-06
Abstract: In one aspect, a method performed by a first network entity in a communications network is provided. The method comprises training a model to obtain a local model update comprising an update to values of one or more parameters of the model, in which training the model comprises inputting training data into a machine learning algorithm. The method further comprises applying a serialisation function to the local model update to construct a serial representation of the local model update, thereby removing information indicative of a structure of the model, and transmitting the serial representation of the local model update to an aggregator entity in the communications network.
Patent WO-2021043663-A1 (WO)
Title: Betätigungsvorrichtung zur montage an einem fahrzeugteil, fahrzeug sowie betätigungsverfahren zum auslösen einer fahrzeugfunktion
Inventor: BUSCHMANN GERD
IPC: E05B81/76
Filed: 2020-08-27
Abstract: Die Erfindung betrifft eine Betätigungsvorrichtung (3) zur Montage an einem beweglichen Fahrzeugteil (2), insbesondere in Form einer Tür oder einer Klappe, aufweisend ein elektrisches Schaltmittel (20) mit einem Schaltelement (21) zum Auslösen einer Fahrzeugfunktion, und eine Gehäuseeinheit (10) mit zumindest einem ersten und einem zweiten Gehäuseelement (11, 12), die zumindest teilweise einen Gehäuseinnenraum (13) bilden, in welchem das Schaltelement (21) angeordnet ist. Ferner betrifft die Erfindung ein Fahrzeug (1), sowie ein Betätigungsverfahren (100).
Patent WO-2021043724-A1 (WO)
Title: Use of pyrvinium for the treatment of a ras pathway mutated acute myeloid leukemia
Inventor: TAMBURINI JÉRÔME
IPC: A61K31/519
Filed: 2020-08-31
Abstract: Acute myeloid leukemia (AML) are heterogeneous malignancies arising from the multistep transformation of bone marrow immature cells. The inventors showed that RAS pathway mutations were detected in 40% of  FLT3-  and  NPM1 -unmutated AML cases and correlated with higher white blood cell count, blast cell percentage and reduced survival after intensive therapy. Building on genetic models of RAS activation, they highlighted the leukemogenic potential of RAS pathway alterations, and the efficacy and limitations of MEK inhibitors in this context. From high-content chemical screens, the inventors unraveled pyrvinium pamoate – an anthelminthic drug approved in human patients – as displaying a preferential cytotoxicity against RAS activated cells. This potential clinical candidate demonstrated a robust synergistic activity with the MEK inhibitor trametinib, including in primary samples from AML patients. Together the data suggest that RAS pathway altered cases may represent a specific AML subtype, in which the anti-leukemic molecule pyrvinium pamoate may represent a new promising therapeutic strategy.
Patent WO-2021058481-A1 (WO)
Title: Threaded connection including and intermediate shoulder
Inventor: FOTHERGILL ALAN
IPC: E21B17/042
Filed: 2020-09-22
Abstract: A threaded tubular connection comprises a first tubular (12) component and a second tubular component (14). The first tubular component (12) includes a female portion (10) defined on an interior surface of the first tubular component. The female portion includes an inner threaded portion (16d) and an outer threaded portion (16b) which are offset radially with respect to a longitudinal axis of the first tubular component by a first shoulder (26). The second tubular component (14) includes a male portion (18) defined on an exterior surface of the second tubular component. The male portion is to be inserted into the female portion, and includes an inner threaded portion (18d) and an outer threaded portion (18b) which are offset radially with respect to a longitudinal axis of the second tubular component by a second shoulder (28). The second shoulder is to abut the first shoulder once the male portion is connected to the female portion. The threaded tubular connection comprises an inner short length fluid tight seal.
Patent WO-2021083600-A1 (WO)
Title: Method for virtual configuration of an automation system
Inventor: HAWKRIDGE VITUS
IPC: G05B19/418
Filed: 2020-10-01
Abstract: The invention relates to a Method for virtual configuration of an automation system (1), which comprises at least one standard automation component (2, 3, 4) and at least one individually created automation component (5), the method comprising the following steps: Providing an engineering system (6) allowing the virtual configuration of a structure of an automation system (1); Providing a pre-configured virtual model for each standard automation component (2, 3, 4) of the automation system (1) by the engineering system (6); Selecting at least one standard automation component (2, 3, 4) and inserting the corresponding pre-configured virtual model(s) into the virtual configuration; Selecting at least one individually created automation component (5) and inserting at least one externally programmed virtual model mapping the selected individually created automation component(s) (5) into the virtual configuration.
Patent WO-2021083673-A1 (WO)
Inventor: SMORENBURG PETRUS
IPC: G02F1/35
Filed: 2020-10-15
Abstract: A high harmonic radiation source and associated method of generating high harmonic radiation is disclosed. The high harmonic radiation source is configured to condition a gas medium by irradiating the gas medium with a pre-pulse of radiation, thereby generating a plasma comprising a pre-pulse plasma distribution; and irradiate the gas medium with a main pulse of radiation to generate said high harmonic radiation. The conditioning step is such that the plasma comprising a pre-pulse plasma distribution acts to configure a wavefront of said main pulse to improve one or both of: the efficiency of the high harmonic generation process and the beam quality of the high harmonic radiation. The high harmonic radiation source further may comprise a beam shaping device configured to shape said customized pre-pulse prior to said conditioning.
Patent WO-2021099052-A1 (WO)
Inventor: THEOBALD FRANK
IPC: B21B37/74
Filed: 2020-10-21
Abstract: Die Erfindung betrifft ein Verfahren zum Einstellen einer Auslauftemperatur eines aus einer wenigstens zweigerüstigen Walzstraße (3) auslaufenden Metallbands (2), wobei die Auslauftemperatur mittels eines Prozessmodells unter Berücksichtigung eines Zusammenhangs zwischen einer Bandumformung und/oder einer Abkühlrate des Metallbands (2) durch wenigstens ein Kühlmedium und durch wenigstens eine feste Walzstraßenkomponente und/oder einer Walzgeschwindigkeit in einem letzten Walzgerüst (7) der Walzstraße (3) einerseits und der Auslauftemperatur andererseits eingestellt wird. Um ein kostengünstiger realisierbares Verfahren zu schaffen, wird nach einer unter Verwendung des Prozessmodells erfolgten Ermittlung einer eingriffsbedingten Abweichung der Bandumformung und/oder der Walzgeschwindigkeit in dem letzten Walzgerüst (7) von in dem Zusammenhang enthaltenen Setzwerten für die Bandumformung und/oder die Walzgeschwindigkeit in dem letzten Walzgerüst (7) mittels des Prozessmodells eine mit der eingriffsbedingten Abweichung verbundene Abweichung der Auslauftemperatur von einer in dem Zusammenhang enthaltenen Solltemperatur ermittelt, wobei die Bandumformung in dem letzten Walzgerüst (7) und in einem oder mehreren vorgelagerten Walzgerüsten (5, 6) der Walzstraße (3) mittels des Prozessmodells in Abhängigkeit der Abweichung der Auslauftemperatur derart geändert wird, dass die Auslauftemperatur der Solltemperatur entspricht.
Patent WO-2021122172-A1 (WO)
Title: Systèmes et procédés de segmentation automatique en imagerie médicale au moyen de multiples modèles de segmentation de structure anatomique
Inventor: LAAKSONEN HANNU
IPC: G06T7/12
Filed: 2020-12-08
Abstract: Systèmes et procédés de segmentation de structure anatomique dans des images médicales utilisant de multiples structures anatomiques, d'instructions et de modèles de segmentation. Un système basé sur un réseau destiné à une segmentation d'image automatique, comprenant : un processeur configuré : pour accéder, par l'intermédiaire du réseau, à une bibliothèque de différents modèles de segmentation d'image ; pour sélectionner et appliquer la totalité ou un sous-ensemble des modèles de segmentation d'image à utiliser pour tracer une ou plusieurs structures anatomiques sélectionnées par un utilisateur par l'intermédiaire d'une interface utilisateur ; et pour combiner des résultats de différentes conclusions de modèle de segmentation.
Patent WO-2021122747-A1 (WO)
Inventor: VILSMEIER STEFAN
IPC: G06K9/62
Filed: 2020-12-16
Abstract: Disclosed is a computer-implemented method which encompasses registering a tracked imaging device such as a microscope having a known viewing direction and an atlas to a patient space so that a transformation can be established between the atlas space and the reference system for defining positions in images of an anatomical structure of the patient. Labels are associated with certain constituents of the images and are input into a learning algorithm such as a machine learning algorithm, for example a convolutional neural network, together with the medical images and an anatomical vector and for example also the atlas to train the learning algorithm for automatic segmentation of patient images generated with the tracked imaging device. The trained learning algorithm then allows for efficient segmentation and/or labelling of patient images without having to register the patient images to the atlas each time, thereby saving on computational effort.
Patent WO-2021130080-A1 (WO)
Title: Procédé d'analyse d'une couche fonctionnelle d'une cellule électrochimique ou d'une application de capteur électrochimique
Inventor: LEERATANAPHANIT SARAYUT
IPC: H01M8/1018
Filed: 2020-12-16
Abstract: L'invention concerne un procédé et un dispositif d'analyse d'une couche fonctionnelle (10) d'une cellule électrochimique ou d'une application de capteur électrochimique, le procédé comprenant les étapes suivantes de : i) transport d'une quantité prédéfinie de gaz d'essai vers une première surface (11) de la couche fonctionnelle (10) ; et ii) détermination quantitative de la quantité de gaz d'essai traversant la couche fonctionnelle (10) au moyen d'une unité de détection (3) qui est disposée sur une seconde surface (12) de la couche fonctionnelle (10), ladite seconde surface étant disposée à l'opposé de la première surface (11) de la couche fonctionnelle (10).
Patent WO-2021122841-A1 (WO)
Title: Système d'éclairage pour zones extérieures
Inventor: PIERS HARALD
IPC: F21S8/00
Filed: 2020-12-16
Abstract: L'invention concerne un système d'éclairage (10) pour éclairer des zones extérieures (5), telles qu'un terrain de sport, par exemple. Le système d'éclairage (10) comprend une pluralité de lampes (10) comprenant une pluralité d'éléments d'éclairage (20), disposés de manière non plane sur un cadre (50) ou dans au moins un boîtier (11), pour générer une pluralité de faisceaux lumineux (25) ayant un axe optique (23) sensiblement dans la direction des zones extérieures (5) et au moins un élément de protection (21) disposé dans une région supérieure (22) de la pluralité d'éléments d'éclairage (20), agencé de manière à protéger au moins une partie de la pluralité de faisceaux lumineux (25) dans la direction de l'horizon (8) et au-dessus de celui-ci à l'opposé du sol.
Patent WO-2021151614-A1 (WO)
Title: Spannungswandler
Inventor: KNAB WOLFGANG
IPC: H01F27/28
Filed: 2020-12-30
Abstract: Die Erfindung betrifft einen Spannungswandler (1). Der Spannungswandler (1) umfasst wenigstens einen Magnetkern (9) mit einem Wicklungsschenkel (12), um den herum Wicklungen des Spannungswandlers (1) angeordnet sind, einem von dem Wicklungsschenkel (12) beabstandeten Basisschenkel (13) und zwei Seitenschenkeln (14), die jeweils den Wicklungsschenkel (12) und den Basisschenkel (13) miteinander verbinden. Ferner umfasst der Spannungswandler (1) einen Deckel (3), der für jeden Magnetkern (9) eine Positionierfassung (21) aufweist, in der der Magnetkern (9) an dem Deckel (3) positioniert ist, und für jeden Magnetkern (9) eine Halterung (11) mit zwei voneinander beabstandeten Rahmenelementen (23), die auf einander gegenüberliegenden Seiten des Magnetkerns (9) jeweils entlang der beiden Seitenschenkel (14) und des Basisschenkels (13) verlaufen und jeweils mit dem Deckel (3) verbunden sind.
Patent WO-2021233578-A1 (WO)
Inventor: OSTROSKY JAMES P
IPC: B60K15/035
Filed: 2021-05-18
Abstract: L'invention concerne un ensemble clapet destiné à fermer une sortie d'une valve, et un ensemble valve qui utilise l'ensemble clapet et qui comprend un support de base et un joint. Le joint est fixé au support de base. Le joint comprend une partie arquée qui s'arque sur le support de base de telle sorte que la partie arquée est espacée du support de base. Un procédé de formation d'un ensemble clapet comprend la fixation d'un matériau élastomère à un support de base pour former un joint qui comprend une partie arquée qui s'arque sur le support de base de telle sorte que la partie arquée est espacée du support de base. Le support de base est formé d'un matériau rigide qui est différent du matériau élastomère.
Patent WO-2022063427-A1 (WO)
Inventor: PANDHARPURE AMAR
IPC: G06Q50/06
Filed: 2021-09-14
Abstract: An intelligent electric meter includes metering components for measuring energy consumption by one or more devices used by a customer in a building, a controller electrically coupled to the metering components and structured to control operations of the metering components and receive energy consumption data based on the measured energy consumption from metering components, a software device electrically coupled to the controller and structured to instruct the controller to monitor the energy consumption data, calculate energy consumption charges for the customer based at least in part on the energy consumption data, and generate a bill and energy usage data for a predefined period, and a communication device electrically coupled to the controller and the software device and structured to transmit the bill and energy usage data to the customer via a defined communications channel.
Patent WO-2021144280-A1 (WO)
Title: Method for filling a package with packs
Inventor: DRAGHETTI FIORENZO
IPC: B65G47/08
Filed: 2021-01-13
Abstract: A method for filling a package with a group of pairs of packs, comprising supplying a group of pairs of packs simultaneously from a transport device to a package, vertically spacing the two packs of each pair of packs of the group of pairs of packs from each other in the package, and horizontally spacing each pair of packs from each other in the package. The method further comprises maintaining a horizontal spacing between each pair of packs of the group of pairs of packs while supplying the group of pairs of packs to the package by guiding the pairs of packs of the group of pairs of packs along space bars provided in the transport device.
Patent WO-2021156037-A1 (WO)
Title: Verfahren und steuervorrichtung zum automatischen einstellen eines betriebsmodus eines hybridfahrzeugs, sowie hybridfahrzeug
Inventor: SONNTAG ACHIM
IPC: B60W20/16
Filed: 2021-01-15
Abstract: Die Erfindung betrifft ein Verfahren zum automatischen Einstellen eines Betriebsmodus eines Hybridfahrzeugs (1), bei welchem nach Ermittlung einer Route (6) zu einem Ziel (7) überprüft wird, ob eine Entfernung zum Ziel (7) größer als eine rein elektrisch zurücklegbare Reichweite des Hybridfahrzeugs (1) ist, wobei das Hybridfahrzeug (1) automatisch in einen Hybridmodus versetzt wird, wenn die Entfernung zum Ziel (7) größer als die rein elektrisch zurücklegbare Reichweite des Hybridfahrzeugs (1) ist, und das Hybridfahrzeug (1) automatisch in einen rein elektrischen Fahrmodus versetzt wird, wenn die Entfernung zum Ziel (7) nicht größer als die rein elektrisch zurücklegbare Reichweite des Hybridfahrzeugs (1) ist. Des Weiteren betrifft die Erfindung eine Steuervorrichtung (5) zum Durchführen eines derartigen Verfahrens sowie ein Hybridfahrzeug (1) mit einer derartigen Steuervorrichtung (5).
Patent WO-2021151770-A1 (WO)
Inventor: DÖRR THOMAS
IPC: A61N1/05
Filed: 2021-01-21
Abstract: La présente invention concerne un stimulateur cardiaque sans fil implantable (1) configuré pour fournir une stimulation antibradycardique d'un cœur humain ou animal, comprenant : une source d'énergie électrique (120), un capteur (140) configuré pour détecter des potentiels intracardiaques du cœur, un générateur d'impulsions (140) configuré pour générer des impulsions de stimulation électrique, une unité de commande (140) pour commander le générateur d'impulsions, l'unité de commande étant configurée pour inhiber la génération d'une impulsion de stimulation électrique lorsqu'un potentiel intracardiaque est détecté, l'unité de commande étant en outre configurée pour éteindre de manière permanente le générateur d'impulsions après l'écoulement d'une période prédéterminée et/ou après un événement prédéfini détecté par le stimulateur cardiaque (1), un pôle d'électrode (220, 250) pour la stimulation électrique et la détection de potentiels intracardiaques, au moins un élément de fixation (230, 260) pour fixer le stimulateur cardiaque (1) au tissu cardiaque, le stimulateur cardiaque sans fil implantable (1) étant adapté de telle sorte qu'une durée de vie du stimulateur cardiaque sans fil implantable (1) est inférieure à un an, en particulier inférieure à un mois, en particulier inférieure à deux semaines.