baber/WOPTO huggingface dataset:
Patent JP-3064281-B1 (JP)
Title: プリント基板の溝加工装置
IPC: B23C3/30
Filed: 1999-05-31
Granted: 2000-07-12
Abstract: 【要約】
【課題】  案内部材間の間隔をプリント基板の厚さに応 じて容易且つ無段階に調整できると共に、その調整作業 の自動化を容易に促進できるようにする。
【解決手段】  押圧案内部材11側に係合体40を、押圧案 内部材11を押圧方向に移動自在に支持する支持枠1 側 に、係合体40に固定案内部材4 側から係合し且つ係脱方 向に移動可能な規制体44を夫々設け、規制体44を係合方 向に付勢する付勢手段48と、規制体44を係脱方向の任意 の位置で固定するクランプ手段46とを設け、係合体40と 規制体44との少なくとも一方に、規制体44の係脱方向へ の移動により、固定案内部材4 と押圧案内部材11との間 隔が変化するように他方に対して係合する傾斜係合面4 3,45 を設ける。
Patent JP-2964247-B1 (JP)
Title: 繊維用柔軟仕上げ剤および仕上げ処理方法
IPC: D06M13/184
Filed: 1998-07-10
Granted: 1999-10-18
Abstract: 【要約】
【課題】  繊維に対し、耐久性のある柔軟性と共に吸水 性も付与する仕上げ剤の提供。
【解決手段】  カルボキシル基含有ワックス（ａ）と下 記化合物（ｂ）との反応生成物（Ｘ）およびアミノ変性 シリコーン（Ｙ）を組み合わせてなることを特徴とする 繊維用柔軟仕上げ剤。
（ｂ）：ＨＬＢ値が８以上、重量平均分子量が３００〜 １０，０００で、かつカルボキシル基との反応性基を有 する化合物。
Patent JP-2857387-B1 (JP)
Title: 管の差し込み・溶融長さマーキング治具
IPC: F16L47/02
Filed: 1997-11-19
Granted: 1999-02-17
Abstract: 【要約】
【課題】  管端より規定の差し込み・溶融長さを確保す るための標線の記入を定規を使用せずに簡易に実施可能 とすることにより、管と継ぎ手金物の接合品質を安定さ せ、接合不良による漏水を減少させることができる管の 差し込み・溶融長さマーキング治具を提供する。
【解決手段】  マーキングすべき管１の管端２が挿入可 能な円筒状の筒体４と、筒体４の外周にに設けられたマ ーキングペン６の軸部を嵌装する嵌装部１３と筒体４の 内部に貫通するマーキングペン６のペン先挿入穴８から なるマーキングペン保持部７と、マーキングペン６をマ ーキングペン保持部７に着脱自在に保持する保持手段９ と、一端が閉鎖され、筒体４の外面に装着される半割り の外筒５とからなり、外筒５の装着位置を調整可能とす ることにより、マーキング位置１２を変更可能とした管 の差し込み・溶融長さマーキング治具。
Patent JP-2987590-B1 (JP)
Title: 多段式凍結装置及び方法
IPC: F25D3/11
Filed: 1998-12-04
Granted: 1999-12-06
Abstract: 【要約】
【課題】  断熱トンネル内の各コンベヤ部分における温 度分布を改善し、食品等の被凍結物を効率よく均一に凍 結させることができ、冷媒の冷熱を有効に利用できる多 段式凍結装置及び方法を提供する。
【解決手段】  多段式凍結装置におけるコンベヤ１１， １２，１３の側方に、開閉扉１６を有する仕切壁１７を 設け、最下段のコンベヤ１３を除く各コンベヤの１１， １２下部に、被凍結物の落下部が開口し、コンベヤ幅方 向が断熱トンネル側壁方向に突出した仕切板１８を設け て各コンベヤ間を仕切ることにより、上下の各コンベヤ 部分を独立したトンネル構造にする。
Patent JP-3010214-B1 (JP)
Title: 表面が改質された真空材料とその表面改質方法
IPC: C23C14/06
Filed: 1998-12-09
Granted: 2000-02-21
Abstract: 【要約】
【課題】  真空材料の真空中における摩擦特性を改善 し、トライボロジー特性の向上を図る。
【解決手段】  真空材料の表面に、六方晶窒化ホウ素及 び銅をスパッタ蒸着してこれらの混合膜を形成し、真空 中における摩擦係数を低減させる。
Patent MD-2622-B1 (MD)
Title: Instalation for bread-crumbs drying
Inventor: IVANOV LEONID
IPC: A23L5/30
Filed: 2004-04-01
Abstract: The invention refers to the food industry, namely to an installation for bread-crumbs drying.The installation for bread-crumbs drying includes a microware oscillator, a transmitting line, an applicator-waveguide with slot, containing two sectors and a conveyer. The ultimate sector of the applicator consists of two symmetrically diverging elements with decreasing sections. Between the symmetrically diverging elements of the applicator it is installed an infra-red radiation source.The result of the invention consists in simplifying the drying process and in improving the quality of the final product.
Patent NO-324897-B1 (NO)
Title: Fremgangsmate for a lete etter et hydrokarbonholdig undergrunnsreservoar
Inventor: ELLINGSRUD SVEIN
IPC: G01V3/12
Filed: 2002-01-14
Abstract: Det er beskrevet et system for å detektere eller bestemme beskaffenheten til et undergrunnsreservoar. Et elektromagnetisk felt blir påtrykket ved å bruke en dipolantennesender (34), og det blir detektert ved å benytte en dipolantennemottaker (35). Målingene blir tatt med antennen både på linje og parallelt, og differansen mellom de to sett med målinger blir utnyttet. En karakteristisk differanse indikerer et lag med høy resistivitet, som svarer til et hydrokarbonreservoar.
Patent NO-334508-B1 (NO)
Title: Fremgangsmåte for gradvis deformering av en initiell objektfordeling i et heterogent medium, generert ved simulering av en stokastisk modell av objekt-type, for å best tilpasse den til pålagte fysiske restriksjoner
Inventor: HU LIN-YING
IPC: G01V11/00
Filed: 2002-03-06
Abstract: Det er beskrevet en geostatisk fremgangsmåte for gradvis deformering av en innledende fordeling av objekter, f.eks. av geologisk type, fra målinger eller observasjoner, for best mulig å tilpasse dem til påførte fysiske begrensninger av f.eks. hydrodynamisk type. Objektene som er fordelt i en sone i et heterogent medium i henhold til en Poisson-punktprosess i form av figurative punkter med en punktdensitet ?(x) som varierer i henhold til deres posisjon (x) i sonen, en realisering av en uniform, tilfeldig vektor i henhold til hvilken posisjonen av hvert punkt blir definert mens den respektive densitet ?(x) blir dannet, og den uniforme, tilfeldige vektor blir gradvis modifisert i henhold til en gradvis deformeringsprosess for å oppnå gradvis migrering av hvert objekt, inntil en endelig realisering som på best mulig måte er justert til parameterne i forhold til mediets struktur, slik som hydrodynamiske parametere, blir oppnådd. Anvendelser: geostatisk modellering av heterogene medier, bestående av forskjellige objekter: f.eks. sprekker, kanaler, vesikler, osv.
Patent NO-337556-B1 (NO)
Inventor: PENTTINEN TAPANI
IPC: B32B27/10
Filed: 2004-04-22
Abstract: The invention relates to a lid (1) that can be heat-sealed to the opening of a package (2) and peeled off as the package is opened. In addition, the invention comprises methods for manufacturing such a lid and a package sealed with the lid, and also a sealed package equipped with a lid. The lid (1) consists of a fibrous material layer (6), whichmay be paper or cardboard, a polymer oxygen-barrier layer (7), suitable materials of which are polyethylene terephthalate (PET), ethylene vinyl alcohol copolymer (EVOH) or polyamide (PA), and a polymer heat-seal layer (8). In accordance with the invention, the heat-seal layer (8) combines ethylene methyl acrylate copolymer (EMA), ethylene vinyl acetate copolymer (EVA) and polyamide wax, adherence of the heat-seal layer directly to the oxygen-barrier layer (7) having been allowed without any intermediate binder. During the manufacture of the lid, the oxygen-barrier and heat-seal layers (7, 8) can be applied onto paper or cardboard by coextrusion. The packages equipped with a lid in accordance with the invention comprises boxes, cups or goblets, for instance, into which foodstuffs, such as drinks, nutrients fats or ready-made foods have been packaged.
Patent NO-333829-B1 (NO)
Title: Fremgangsmåte og system for installasjon av en kabel inne i en rørkanal for utplassering i en brønn.
Inventor: BIXENMAN PATRICK W
IPC: E21B17/20
Filed: 2004-08-13
Abstract: En fremgangsmåte til opphenging av et elektrisk nedsenkbart pumpesystem inne i en brønnboring inkluderer innsetting av en elektrisk kabel inne i en rørkanal, så som et kveilerør, før rørkanalen utplasseres nede i hullet. Den elektriske kabelen settes inn i rørkanalen ved overflaten og tillates å foldes sammen på en slik måte at den elektriske kabel foldes sammen og får ensartet kontakt med en innvendig overflate i rørkanalen med en flerhet av lokaliseringer langs hele lengden av kveilerøret for å hindre langsgående bevegelse av den elektriske kabelen inne i rørkanalen. Et elektrisk nedsenkbart pumpesystem blir deretter forbundet til rørkanalen, og den elektriske kabelen forbindes til en elektrisk motor i det elektrisk nedsenkbare pumpesystemet. Det elektrisk nedsenkbare pumpesystemet og rørkanalen settes inn i brønnboringen.
Patent NO-334382-B1 (NO)
Inventor: WEBB RANDY LEE
IPC: A61P21/00
Filed: 2004-12-15
Abstract: The invention relates to a pharmaceutical composition comprising (i) a renin inhibitor, (ii) a calcium channel blocker (CCB), and (iii) a diuretic and to a method of treatment of a condition or a disease selected from the group consisting of hypertension, heart failure such as (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, diabetic cardiac myopathy, supraventricular and ventricular arrhythmias, atrial fibrillation, atrial flutter, detrimental vascular remodeling, myocardial infarction and its sequelae, atherosclerosis, angina (whether unstable or stable), renal insufficiency (diabetic and non- diabetic), heart failure, angina pectoris, diabetes, secondary aldosteronism, primary and secondary pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis (including IgA nephropathy), renal fibrosis, scleroderma, glomerular sclerosis, proteinuria of renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, peripheral vascular disease, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzheimer's), glaucoma and stroke, pulmonary and hepatic fibrosis, fibrotic diseases resulting from accumulation of excess extracellular matrix induced by TGF, and proliferative diseases of smooth muscle cells, including uterine fibroids comprising administering a therapeutically effective amount of said pharmaceutical composition to a mammal in need of such treatment.
Patent NO-330826-B1 (NO)
Title: Anordning for testing av endestillinger av bevegelige sporvekseldeler
Inventor: SCHNEDL KARL
IPC: B61L5/10
Filed: 2005-03-04
Abstract: Ved en endestillings-testeanordning for bevegelige sporvekseldeler (3), med et testestangsystem og et testerhus (12) som testestangsystemet er innført i og hvori det er anordnet i det minste en detektor for registrering av en endestilling av testestangsystemet, er testestangsystemet svingbart tilsluttet den bevegelige sporvekseldel (3) i et vertikalplan som ligger på tvers av skinnenes lengderetning, hvor testestangsystemet omfatter i det minste en stang (8) med sirkelrundt tverrsnitt, hvilken stang (8), på omkretsen av det område som stikker tettende inn i testerhuset (12), er forsynt med i det minste en koblingsflanke (13) som samvirker med en bryterkontakt (16).
Patent NO-330794-B1 (NO)
Inventor: MATSUMOTO HIROO
IPC: C07D311/58
Filed: 2005-03-23
Abstract: There is provided a method for producing aminobenzopyran compound, which results in little wastes, has no influence on reactors and necessitates a simple work-up procedure. Concretely, it is a method for producing aminobenzopyran compound of formula (2) <CHEM> characterized by reducing a nitro group on 2,2-dimethyl 2H-1-benzopyran compound of formula (1) <CHEM> with hydrazine in the presence of a metal catalyst.
Patent NO-323911-B1 (NO)
Title: Ventilasjonsanlegg og fremgangsmate for ventilering av bygninger  med oppholdsrom.
Inventor: AMUNDSEN AAGE
IPC: F24F11/30
Filed: 2005-11-03
Abstract: Ventilasjonssystem for mindre bygg som styres slik at man alltid har undertrykk inne, slik at fuktig, varm inneluft ikke trenger ut i bygningskonstruksjonen der fukt og råte kan opptre. Dette oppnås med en regulering av mekanisk avtrekk styrt av en trykksensor plassert i øvre del av ventilert rom, og at reguleringen tilstreber null trykkforskjell mellom loft og underliggende rom. Dette er utført i en foretrukket form med regulering av avtrekket styrt av en temperatursensor plassert i en åpen luftkanal/-rør mellom loft og underliggende rom der reguleringspunktet ligger mellom normal inne- og utetemperatur i den kalde årstid. Overtrykk og undertrykk vil påvirke sensoren ved at den omstrømmes av hhv. varm og kald luft, og nulltrykk oppnås når regulatoren finner et reguleringspunkt mellom disse lufttemperaturene.
Patent NO-335734-B1 (NO)
Inventor: SZELENYI ISTVAN
IPC: A61K31/44
Filed: 2006-07-17
Abstract: The subject of the present invention is to provide a combination of two centrally acting analgesics, flupirtine and tramadol, or their respective pharmaceutically acceptable salts for the treament of pain.
Patent NO-337754-B1 (NO)
Inventor: ZURFLUH FRANZ
IPC: H05K1/14
Filed: 2007-12-10
Abstract: The electronic circuit arrangement (30) for controlling a process device (40) comprises a process interface circuitry (1) and a processing circuitry (2), wherein the process interface circuitry (1) is designed for receiving process signals from the process device (40) and converting the process signals into converted signals and/or digital data, which converted signals and/or digital data are transmitted to the processing circuitry (2), and wherein the processing circuitry (2) is designed for processing the converted signals and/or digital data and for outputting processed signals and/or digital data, which processed signals and/or digital data are transmitted to the process interface circuitry (1), and wherein the process interface circuitry (1) is designed for converting the processed signals and/or digital data into control signals, which control signals are transmitted to the process device (40). The process interface circuitry comprises one or more first printed circuit board assemblies (10), and the processing circuitry comprises one or more second printed circuit board assemblies (20), which second printed circuit board assemblies (20) are different from the first printed circuit board assemblies (10), and wherein each second printed circuit board assembly (20) is electrically connected to at least one of the first printed circuit board assemblies. The circuit arrangement (30) may find applications in high or medium voltage devices, in drives and in power converters.
Patent NO-333816-B1 (NO)
Title: Anordning ved bergboremaskin.
Inventor: HAUGHOM PER OLAV
IPC: E21B7/08
Filed: 2008-06-05
Abstract: Anordning ved bergboremaskin (1) som omfatter et boreparti (4) og et strengparti (6), og hvor bergboremaskinen (1) mellom borepartiet (4) og strengpartiet (6) er forsynt med et styreledd (8).
Patent NO-331342-B1 (NO)
Title: Stigerors strekkanordning
Inventor: OHE CHRISTIAN B VON DER
IPC: E21B17/01
Filed: 2009-09-15
Abstract: Stigerørs strekkanordning (1) som omfatter en bærestruktur (2) for et antall hydrauliske aktuatorer (4), hvor bærestrukturen (2) er forbundet med et fartøys konstruksjon (18), og hvor hver aktuator (4) er forbundet med bærestrukturen (2) og med et marint stigerør (8), og hvor stigerørets strekkanordning (1) er innelukket.
Patent NO-346679-B1 (NO)
Inventor: ORGELDINGER WOLFGANG
IPC: B65D21/08
Filed: 2013-03-11
Abstract: The system has side wall parts (11, 11a, 12, 12a) with hinged support elements (15, 16) that are connected with the side wall part, so that the elements form a support in a hinged position, which enlarges a support space of a crate. The elements are mounted on respective upper sides of the wall parts and are held by guides attached to the parts in the hinged position, and the elements are integrated in the hinged position in the walls such that the elements are not protruding over the thickness of the wall parts.
Patent NO-341990-B1 (NO)
Inventor: LAING MORAY
IPC: G06F17/50
Filed: 2015-12-22
Abstract: A computing device configured to determine when an alarm is triggered for a drilling operation is provided. Measured drilling data that includes a value measured for an input variable during a previous connection event of a drilling operation is received. A predicted value for a fluid flow back measure is determined by executing a predictive model with the measured drilling data as an input. The predictive model is determined using previous drilling data that includes a plurality of values measured for the input variable during a second drilling operation. The second drilling operation is a previous drilling operation at a different geographic wellbore location than the drilling operation. A fluid flow back measurement datum determined from sensor data is compared to the determined predicted value for the fluid flow back measure. An alarm is triggered on the drilling operation based on the comparison.
Patent PL-95583-B1 (PL)
IPC: D01H4/12
Filed: 1975-01-28
Abstract: 1491133 Bearings; lubrication TELDIX GmbH 28 Jan 1975 [30 Jan 1974 5 June 1974] 3648/75 Heading F2A A rotary device for use in a spinning unit for open-end spinning comprises a stator 11, a resiliently-supported bearing 7 carried by a projecting portion 10 of the stator 11, and a rotor 1 carried by the bearing 7; wherein the rotor 1 includes a pin 6 which is rotatably mounted in the bearing 7 and a cup-shaped portion 9 co-axially surrounding the pin 6, the bearing 7 and the projecting portion 10; wherein a stator winding 19 is mounted on the projecting portion 10 within the cup-shaped portion and magnets 20 are provided on the inner surface of the cup-shaped portion 9 facing the winding 19 and arranged to be coaxial to the axis of rotation 8 of the rotor 1; wherein the rotor 1 has its largest moment of inertia about the axis of rotation 1; and wherein the centre of gravity of the rotor 1 lies within the bearing 7. Figs. 2 and 3 (not shown) illustrate details of the bearing arrangement in an embodiment. A sintered or plastics bush 23 is carried by a grooved sleeve 25 and a surrounding resilient bush 28. Axial location is by means of a magnetic ring 48 and a coaxial return ring 49, which hold a disc 47, secured to a bearing pin 22, in contact with the bush 23. The disc 47 also acts as an oil thrower and, in combination with labyrinth rings 50, 51, provide sealing for the unit. Lubrication is provided by felt reservoirs 30, 31, connected by channels 27 and 45.
Patent PL-111060-B1 (PL)
Title: Preparation of novel isoindoline derivatives
IPC: C07C51/56
Filed: 1976-09-20
Abstract: 1498348 Naphthyridine derivatives RHONEPOULENC SA 17 Sept 1976 [22 Sept 1975] 38671/76 Addition to 1417935 Heading C2C Novel compounds II in which Y is H, halogen, C 1-4 alkyl, C 1-4 alkoxy, CN or NO 2 and R is H, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 1-4 hydroxyalkyl or phenyl, and acid addition salts thereof, are prepared by (a) reacting a compound IV with a 1-R-2-chlorocarbonyl-piperazine, or (b) reacting a mixed carbonate of a compound IV with a 1-R-piperazine. Compounds IV are prepared by partial reduction of corresponding imides which are themselves prepared by reacting a trifluoromethyl-substituted anhydride with a 2-amino- 7-Y-naphthyridine. 4 - Trifluoromethyl - phthalic anhydride is prepared by converting 2-amino-4-trifluoromethylbenzoic acid to the methyl ester, diazotizing the ester and reacting the diazo compound with KCN to form methyl 2-cyano-4-trifluoromethylbenzoate, hydrolysing this to form 4-trifluoromethyl-phthalic acid and cyclizing this to form the desired anhydride. Pharmaceutical compositions useful as tranquillizers and anticonvulsants comprise a compound II or a non-toxic acid addition salt thereof, together with a pharmaceutical carrier. The compositions may be in a form suitable for oral, parenteral, rectal or topical administration.
[GB1498348A]
Patent PL-145331-B1 (PL)
Title: Method of obtaining novel derivatives of substituted amide
IPC: C07D471/04
Filed: 1985-07-17
Abstract: The invention provides novel substituted amides of formula: R-CONH-Het in which R is cycloalkyl, cyclohexadienyl, phenyl optionally substituted with one or 2 fluorine atoms or with a hydroxy radical, or substituted at position 3- or 4- with an alkyl or alkyloxy radical, or with a methylenedioxy radical at positions 3- and 4-, or at position 2- or 3- with a dialkylamino radical, or is 3-pyridyl, alkyloxy-3-pyridyl, thienyl, alkylthienyl, furyl, tetrahydropyridyl, pyridazinyl and alkylpyridazinyl, and Het is 2-quinolyl or 1,8-naphthyridin-2-yl, both optionally substituted at position 7- with a halogen atom or a hydroxymethyl, alkyl, alkyloxy, alkyloxyalkyloxy, alkenyloxy or alkynyloxy radical (of 3 or 4 carbon atoms), an alkylthio or benzylthio radical, a phenoxy radical which is optionally substituted (with fluorine, with chlorine or bromine at position 2-, or with an alkyloxy radical or 1 or 2 alkyl radicals) or with pyridyloxy or alkylpiperidyloxy, provided that, when Het is 2-quinolyl, R is other than phenyl, and that the radicals and alkyl portions contain 1 to 4 carbon atoms each in a linear or branched chain. The new products are useful as anxiolytics, hypnotics, anticonvulsants, antiepileptics and muscle relaxants. The invention also provides a process for the preparation of, and pharmaceutical compositions containing, the new compounds.
Patent PL-156158-B1 (PL)
Filed: 1986-05-28
Abstract: Układ blokady impulsów wyzwalających zawierający
blokadę napięciową, znamienny tym, że wyjście (A)
członu blokady napięciowej (1) jest połączone z wejściem
regulatora prędkości (2), wyjście (B) jest połączone z
wejściem regulatora prądu (3), wyjście (D) jest połączone
z wejściem zezwolenia zmiany stanu członu blokady zależnej
prądowo (4), wyjście (G) jest połączone z dodatkowymi
wejściami blokowania impulsów bloków formowania
impulsów wyzwalających (5) i (6) dla obu kierunków
przewodzenia przekształtnika, wejście (C)
członu blokady napięciowej (1) jest połączone z wyjściem
sygnału zablokowania obu kierunków członu blokady
zależnej prądowo (4), wejście (E) jest połączone z wyjściem
blokowania impulsów (5) jednego kierunku, wejście
(F) jest połączone z wyjściem blokowania impulsów drugiego
kierunku członu blokady zależnej prądowo (4),
wejście (H) jest połączone z wyjściem impulsów skojarzonych
bloku formowania impulsów wyzwalających (5)
jednego kierunku, a wejście (I) jest połączone z wyjściem
impulsów skojarzonych bloku formowania impulsów
wyzwalających (6) drugiego kierunku, a wejście (J) z
wyjściem bloku czujników (8).
Patent PL-151829-B1 (PL)
Title: Method of obtaining derivatives of gangliosides
IPC: C07C68/00
Filed: 1985-06-27
Abstract: New functional ganglioside derivatives comprising ester, amide and peracylated derivatives of gangliosides, preparation procedures therefor, pharmaceutical preparations containing the same, and the therapeutic use of the derivatives.
Patent PL-154881-B1 (PL)
IPC: C07D307/52
Filed: 1987-04-14
Abstract: Przedmiotem w ynalazku j e s t sposób otrzym yw ania 2 -C [[5 -/ N ,N -d im e ty lo a m in o / m e ty lo -2 -
f u r a n y lo j-m e ty lo j-tio j-e ta n o a m in y o w z o r z e l. Zw iązek ten j e s t produktem pośrednim w sy n ­
t e z i e środka le c z n ic z e g o o d z ia ł a n iu przeciwwrzodowym, znanego pod nazwą r a n i t i d i n e .
Znany je s t z o p isu p atento w ego b e lg ijs k ie g o nr 857 388 sposób s y n te zy tego zw ią zk u ,
p o le g a ją c y na k o n d e n s a c ji a lk o h o lu 5 -/ N ,N -d im e ty lo a m in o / -m e ty lo fu rfu ry lo w e g o o wzorze 2
z chlorow odorkiem cy ste a m in y i w yodrębnianiu oroduktu na drodze d e s t y l a c j i p r ó ż n io w e j.
Sposób te n j e s t niedogodny do zasto so w an ia te c h n o lo g ic z n e g o z uw agi na używanie d r o g ie j
i trudno d o stęp n ej c y s te a m in y .
N ieo czekiw an ie o k a z a ło s i ę , że można p rzep row adzić r e a k c ję otrzym yw ania zw iązku 1
wychodząc ze zw iązku 2 oraz kwasu S -/ a m in o e ty lo / -tio s ia r k o w e g o /HgN CH gd^SSO ^H /, łatw o
d o stę p n e g o , bo otrzymywanego z t a n i e j e ta n o lo a m in y .
Sposobem według w ynalazku kwas S _/ 2 -a m in o e ty lo / -tio s ia r k o w y poddaje s i ę n a jp ie rw
ogrzew aniu w kwasie so ln ym , k tó re g o s tę ż e n ie w ynosi nie m n iej n iż 20&. Ogrzew anie prowad
z i s i ę w 5O-6O°C, a n a s tę p n ie po dodaniu a lk o h o lu o wzorze 2 r e a k c ję k o n d e n s a c ji prowad
z i s i ę w tem peraturze p o k o jo w e j. Po r e a k c j i w yodrębnia s i ę w znany sposób p ro d u k t,
p rzy czym s to s u je s i ę ro ztw ó r produ ktu w r o z p u s z c z a ln ik u organicznym stosowanym do e k st
r a k c j i , na p rzy k ła d w t o l u e n i e , do d a ls z y c h etapów s y n te z y lu b ew en tu aln ie poddaje d est
y l a c j i p ró żn io w e j.
P o n iższy p rzy k ład i l u s t r u j e w y n a la ze k , nie o g r a n ic z a ją c je g o z a k r e s u . P r z y k ł a d . Do 1 1 ,2 g kwasu S -/ 2 -a m in o e ty lo / -tio s ia r k o w e g o do daje s i ę 4 6 ,5 ml
25^-owego kwasu so ln e g o i ogrzewa w tem peraturze 5O-6O°C 2 h . Roztw ór sch ła d za s i ę do
20°G i dodaje 10,0 g a lk o h o lu 5 -/ N ,N -d im e ty lo a m in o m e ty lo / -fu rfu ry lo w e g o i p ozostaw ia
m ie sza n in ę re a k c y jn ą w tem p e ra tu rze pokojow ej 15 h . N astęp n ie m ie sza n in ę p o r e a k c y jn ą ,
p rz y c h ło d z e n iu , a l k a l i z u j e s i ę 40%-owym roztworem woanym w odotlenku sodowego i e k s t r a ­
h u je toluenem /4 z 50 m l/ . E k s t r a k t y suszy s i ę na bezwodnym s ia rcza n e m sodowym i s t o s u je
154 881
2 154 831
do d a ls z y c h etapów sy n te zy lu b e w e n tu a ln ie po o d d esty lo w an iu r o z p u s z c z a ln ik a p oddaje
d e s t y l a c j i p ró żn io w ej pod c iś n ie n ie m p o n iż e j 10 P a . W ydajność r e a k c j i 72¾.