baber/WOPTO huggingface dataset:
Patent DE-60011997-T2 (DE)
Inventor: BLANEY E
IPC: A61K31/352
Filed: 2000-03-10
Granted: 2005-07-21
Abstract: This invention relates to substituted benzo[1,2-b:5,4-b']dipyran-4-amines which are modulators, agonists or antagonists, of the CCR5 receptor. In addition, this invention relates to the treatment and prevention of disease states mediated by CCR5, including, but not limited to, asthma and a topic disorders (for example, a topic dermatitis and allergies), rheumatoid arthritis, sarcoidosis and other fibrotic diseases, atherosclerosis, psoriasis, autoimmune diseases such as multiple sclerosis, and inflammatory bowel disease, all in mammals, by the use of substituted benzo[1,2-b:5,4-b']dipyran-4-amines which are CCR5 receptor antagonists. Furthermore, since CD8+T cells have been implicated in COPD, CCR5 may play a role in their recruitment and therefore antagonists to CCR5 could provide potential therpeutic in the treatment of COPD. Also, since CCR5 is a co-receptor for the entry of HIV into cells, selective receptor modulators may be useful in the treatment of HIV infection.
Patent DE-60018050-T2 (DE)
Inventor: CARPENTIER ANTOINE
IPC: A61K31/711
Filed: 2000-03-17
Granted: 2006-02-23
Abstract: The invention concerns the use of stabilized oligonucleotides comprising at least an octamer motif of the type: 5′-purine-purine-CG-pyrimdine-pyrimidine-X1X2-3′ wherein the pair X1-X2 is AT, AA, CT or TT, for preparing a medicine with antitumour activity.
Patent DE-60029970-T2 (DE)
Inventor: RICKETTS JEFFRIE
IPC: C22C23/00
Filed: 2000-04-28
Granted: 2007-08-30
Abstract: A cover gas composition for protecting molten magnesium/magnesium alloy includes a fluorine containing inhibiting agent and a carrier gas. Each component of the composition has a Global Warming Potential (GWP) (referenced to the absolute GWP for carbon dioxide at a time horizon of 100 years) of less than 5000.
Patent DE-60030977-T2 (DE)
Inventor: MISSANA MARIE-CHRISTINE
IPC: A61F2/12
Filed: 2000-05-29
Granted: 2007-06-28
Abstract: The invention concerns an implantable breast prosthesis comprising a soft pouch capable of a containing filler substance such as a physiological serum or a silicone gel and which is made side-specific, so as to satisfy aesthetic requirements and for better matching the convexity of the thorax.
Patent DE-60101582-T2 (DE)
Inventor: ADAMOU BRAH IBRAHIM
IPC: C23C18/16
Filed: 2001-10-08
Granted: 2004-11-25
Abstract: Process of production of sizing blade comprises stage of chemical co-deposition of coating comprising nickel-based matrix and ceramic, diamond or carbide particles dispersed within the matrix, over at least a functional part of steel blade. <??>An Independent claim is also included for sizing blade with coating comprising nickel-based matrix and ceramic, diamond or carbide particles dispersed within the matrix, over at least a functional part of blade.
Patent DE-60133127-T2 (DE)
Inventor: PAGOT HENRI
IPC: B60T11/16
Filed: 2001-12-03
Granted: 2009-03-19
Abstract: A master cylinder piston for use in a motor vehicle having a flap ( 22 ) that is biased towards a position to shut off a pressure-fluid passage ( 24 ) by a return spring ( 28 ) resting on a cage ( 30 ). A flange ( 38 ) on a cage ( 30 )for the Spring ( 28 ) is located in an annular groove ( 44 ) provided in the housing ( 20 ) for the flap ( 22 ) when the cage ( 30 ) bears axially on an inner shoulder ( 64 ) of the housing ( 20 ).
Patent DE-60133377-T2 (DE)
Inventor: CHEN CHANGYI
IPC: A61L31/00
Filed: 2001-04-27
Granted: 2009-01-02
Abstract: The present invention relates to decellularized vascular prostheses that are resistant to thrombus occlusion and have a low level of immunogenicity. The vascular prostheses are denuded of cells, and coated with an anti-thrombogenic agent and a growth factor that promotes recellularization and further reduces the immunogenicity. The prostheses have high mechanical strength, resist aneurysm rupture, and allow for secure surgical sutures while maintaining structural integrity. The present invention provides vascular prostheses that are blood vessels, valves or portions of vessels containing valves. The present invention is also useful for coating synthetic vascular stents.
Patent DE-60203609-T2 (DE)
Inventor: JENSEN GRONBAEK
IPC: B01D1/18
Filed: 2002-05-10
Granted: 2006-03-09
Abstract: A method for drying liquid or pasta containing a dry matter. The method comprises the following successive steps: drying in a drying device, such as a spray drying device, until at least a partially dried powder is obtained; supply of the powder to a filter device; and finishing treatment of the powder in a fluid bed. The invention also relates to a drying plant for exercising the method, which drying plant comprises a filter device that is located between a drying device, such as a spray drying device, and a fluid bed.
Patent DE-60206433-T2 (DE)
Inventor: MORELLI MURIEL
IPC: A61K8/34
Filed: 2002-02-27
Granted: 2006-07-20
Abstract: This invention relates to chemical compositions containing caprylyl glycol or an analog thereof, and a particular combination of preservative agents. It further relates to the use of caprylyl glycol or an analog thereof to increase the activity of preservative agents, more in particular to increase the activity of a combination of iodopropynyl butyl carbamate and phenoxyethanol
Patent DE-60207893-T2 (DE)
Inventor: YEUNG JEFFREY E
IPC: A61B19/00
Filed: 2002-12-24
Granted: 2006-08-17
Abstract: An elastically curved suture anchor is resiliently straightened and delivered into tissue by a needle. When the needle is withdrawn, resumption of the curvature provides leverage for anchor rotation as the attached suture is pulled to fasten the anchor within the tissue. A fin at the proximal end of the anchor further increases the rotational leverage and expedites anchor fastening. When two or more anchors with connecting suture are delivered in series on a needle, the tension of the suture helps to draw the anchors together and approximates the pierced tissue.
Patent DE-60214236-T2 (DE)
Inventor: HUHTALA OLLI
IPC: D21F7/00
Filed: 2002-06-12
Granted: 2007-08-23
Abstract: The invention relates to an arrangement for threading a pulp web (W) from the press section ( 1 ) of a pulp machine to the dryer ( 2 ) of the pulp machine. The arrangement comprises a closing tail threading belt ( 3 ) or the like, which is arranged to convey the narrow tail end (W<SUB>h</SUB>) formed on the pulp web (W) inside the dryer ( 2 ), where the tail threading cord travels outside the edge of the normal web line of the pulp web. The tail end (W<SUB>h</SUB>) can subsequently be broadened into a normal-width pulp web (W). The arrangement further comprises means ( 7 ) for gripping the tail end (W<SUB>h</SUB>) in order to bring the tail end inside/between a closing tail threading cord ( 3 ) or the like, whereby the gripping means ( 7 ) are arranged to function at the normal running speed of the pulp machine. The arrangement comprises means ( 4 ) by which the tail threading cord ( 3 ) can be moved inwards from its normal route, towards the pulp web, to travel essentially in the same line with the tail end formed on the edge of the pulp web before the tail end is conveyed inside the tail threading cord, and means ( 5 ) by which the tail threading cord ( 3 ) and the tail end (W<SUB>h</SUB>) inside it can be moved back to the normal route located outside the edge of the pulp web before entering the dryer ( 2 ).
Patent DE-60214713-T2 (DE)
Inventor: HOLMES-FARLEY RANDALL
IPC: A61K31/74
Filed: 2002-07-01
Granted: 2007-09-06
Abstract: Disclosed is a phenyl boronic acid compound represented by Structural Formula (I): Ar is a substituted or unsubstituted aryl group. Z and Z' are independently -O-, -NH- or -S-. X is an electron withdrawing group. R is a substituted or unsubstituted straight chained hydrocarbyl group optionally comprising one or more amine, ammonium, ether, thioether or phenylene linking groups and Y is -H, an amine, -[NH-(CH<SUB>2</SUB>)<SUB>q</SUB>]<SUB>r</SUB>-NH<SUB>2</SUB>, halogen, -CF<SUB>3</SUB>, thiol, ammonium, alcohol, -COOH, -SO<SUB>3</SUB>H, -OSO<SUB>3</SUB>H or phosphonium group covalently bonded to the terminal position of R. Each -NH- in -[NH-(CH<SUB>2</SUB>)<SUB>q</SUB>]<SUB>r</SUB>-NH<SUB>2 </SUB>is optionally N-alkylated or N,N-dialkylated and -NH<SUB>2 </SUB>in -[NH-CH<SUB>2</SUB>)<SUB>q</SUB>]<SUB>r</SUB>-NH<SUB>2 </SUB>is optionally N-alkylated, N,N-dialkylated or N,N,N-trialkylated. q is an integer from 2 to about 10 and r is an integer from 1 to about 5. R<SUB>1 </SUB>and R<SUB>1'</SUB> are independently -H, an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group, or, taken together, are a C2-C5 substituted or unsubstituted alkylene group optionally comprising an amine linking group [-N<SUP>+</SUP>(R<SUP>1a</SUP>)-]. Each R<SUB>1 </SUB>is Structural Formula (I) is preferably -H. R<SUP>1a </SUP>is -H, alkyl, substituted alkyl phenyl or substituted phenyl. Also disclosed is a method of treating obesity in a subject by administering an effective amount of a compound represented by Structural Formula (I) and a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier or diluent.
Patent DE-60222562-T2 (DE)
Inventor: HAYAKAWA SATOSHI
IPC: C08J5/18
Filed: 2002-07-10
Granted: 2008-06-19
Abstract: In heat-shrinkable polyester films, the content of 1,4-cyclohexane dimethanol is 10 to 50 % by mole based on the polyhydric alcohol component and that the heat shrinkage factors of a 10 cm square sample of the films in (A) hot water of 75  DEG C, (B) hot water of 85  DEG C, and (C) hot water of 95  DEG C are 30 to 40 %, 50 to 60 %, and 65 to 77 %, respectively. The films can be produced by drawing under specified conditions.
Patent DE-60224388-T2 (DE)
Inventor: FERRACHAT MARIE-PAULE
IPC: B29C45/37
Filed: 2002-05-17
Granted: 2008-12-18
Abstract: The invention relates to a mold insert, the interior surface thereof having an average quadratic roughness of less than 10 nm. Said insert is covered with a protective layer exhibiting a Vickers hardness of more than 1000 HV, a thickness of between 0.2 and 5 μm, and an adhesive strength greater than 15 N. The invention also relates to a method for the production thereof. The invention is used for the production of ophthalmic lenses.
Patent DE-60305206-T2 (DE)
Inventor: ANDEL TOMAS
IPC: F16H55/30
Filed: 2003-08-25
Granted: 2007-03-01
Abstract: The present invention relates to lightweight sprocket, consisting of a central portion (1) made from light metal alloy, to which a peripheral toothed portion (2) made from ferrous alloy is joined, using rivets (3) for joining said portions (1,2), where said joining is created between radial beams (21) of the peripheral toothed portion (2) and pocket-like recess (13) in the central portion (1), radial beams (21) being overlapped across bottoms of pocket-like recesses (13), and where a thickness of radial beams(21), at least over the joining area, is decreased by 10 to 60%, in relation to full thickness of said toothed peripheral portion (2), and a thickness of a bottom of the pocket-like recess (13) in the central portion (1) is decreased by 20 to 70%, in relation to full thickness of the central portion (1) of the sprocket.
Patent DE-60310646-T2 (DE)
Inventor: BELENSKY ALEXANDER
IPC: A61K35/14
Filed: 2003-06-18
Granted: 2007-10-04
Abstract: The present invention describes methods and compositions comprising new protease inhibitor stabilizers of brain natriuretic peptide (BNP), which prevent or significantly reduce the degradation of BNP in blood based samples, particularly plasma samples. The BNP inhibitors of the invention include D-Phe-Phe-Arg-chloromethylketone (PPACK), D-Phe-Pro-Arg-chloromethylketone (PPRACK), acetyl-Leu-Leu-arginal (leupeptin), N-(N alpha -carbonyl-Arg-Val-Arg-al)Phe (antipain) and diisopropylfluorophosphate (DFP), either alone or in combination. The inhibitors, and combinations thereof, can be directly added to collected blood samples prior to testing in laboratory or clinical settings. In addition, the inhibitors, alone or in combination, can be added to blood-based (e.g., plasma) matrices prior to, or at the time of, the addition of exogenous BNP (e.g., synthetic BNP), to prepare control materials used in BNP analysis and quantification of patient blood samples.
Patent DE-60318760-T2 (DE)
Inventor: MAYOR MICHAEL A
IPC: H04B7/06
Filed: 2003-02-11
Granted: 2009-01-08
Abstract: Enhanced reception of transmitted signals in a communication system is achieved by synchronously combining transmissions from a cluster of transmitters at a distant receiver. The transmitters coordinate transmissions such that each substantially simultaneously transmits the same signal on the same communication channel. As a consequence of the spatial diversity of the transmitters, the transmitted signals arrive at the receiver at different times. The receiver essentially treats the different transmitted signals as though they were different multipath signals from a single transmitter. A multipath equalizer or combiner is used to determine timing offsets among the received signals, and the received signals are time aligned by phase rotating the signals in accordance with the estimated timing offsets. The time-aligned signals are then coherently combined and detected. The combined signal has a greater signal-to-noise ratio than the individual received signals, permitting detection at a greater range or with a lower bit error rate. <IMAGE>   <IMAGE>   <IMAGE>   <IMAGE>
Patent DE-68905059-T2 (DE)
Inventor: MICHAUD PHILIPPE
IPC: C08G73/14
Filed: 1989-03-23
Granted: 1993-06-17
Abstract: New aromatic polyamideimides whose chains contain optionally substituted end groups of maleimido type. 
<??>More precisely, these polymers correspond to the formula: 
<IMAGE>
 in which: D denotes a valency bond, an atom or a divalent group; B denotes a trivalent aromatic radical containing at least 6 carbon atoms; m is at least equal to 1; and X denotes the radical of formula: 
<IMAGE>
 in which R1 and R2 = H or CH3, R3 = CH3, n = 0, 1, 2 or 3 and E = a valency bond or -CH2-. These polymers are obtained by direct reaction of an aromatic diisocyanate, a tricarboxylic acid monoanhydride and a carboxylic monoacid substituted by a maleimido group (itself optionally substituted). 
<??>These polyamideimides can be employed especially for the production of coating films, adhesive substances and moulded articles and can be crosslinked when heated.
Patent DE-68905165-T2 (DE)
Inventor: CANAUD MICHEL
IPC: B29C33/30
Filed: 1989-11-28
Granted: 1993-09-23
Abstract: The invention relates to a process for obtaining a glazing panel provided with a peripheral joint for protecting the edges, in which the glazing panel is clamped in a mould which defines, around the glazing panel, a cavity whose walls correspond to the desired external profile, a material being injected into the said cavity under low pressure. The mould according to the invention consists of modular units (1, 2, 3, 4) made from a mouldable material and joined together by assembly means, at least one modular unit being provided with an injection orifice (3) and at least one other being provided with a vent (4). <IMAGE>
Patent DE-68907109-T2 (DE)
Inventor: HIRAI NOBUKI MITSUI PETROCHEMI
IPC: C08K5/15
Filed: 1989-04-05
Granted: 1993-09-30
Abstract: Compositions for use in the production of molded articles, preferably by injection molding, comprise a ceramic powder and/or a metallic powder and an organic binder, wherein the organic binder comprises a polyalkylene carbonate and an epoxy compound having at least one expocy group in the molecule.
Patent DE-68917518-T2 (DE)
Inventor: MILLER NIGEL DAVID CRUSADER CO
IPC: A61L15/16
Filed: 1989-05-17
Granted: 1995-02-09
Abstract: Fibrous dressings employed as wound contacting materials, may be rendered hypoadherent by coating the body contacting surface with a polymeric coating of a material such as a siloxane block copolymer or a blend thereof with an amine extended polyurethane.
Patent DE-68922999-T2 (DE)
Inventor: GREEN JAMES RALPH
IPC: D03D15/12
Filed: 1989-08-10
Granted: 1995-12-14
Abstract: Heat resistant, durable woven fabrics are prepared with warp yarns comprising certain blends of cotton, nylon and heat resistant fibers.
Patent DE-69000369-T2 (DE)
Inventor: PERSELLO JACQUES
IPC: A61K8/36
Filed: 1990-04-27
Granted: 1993-04-15
Abstract: Silica compatible with metal ions such as zinc, tin or strontium, characterised by a surface OH<-> number expressed as OH<->/nm<2> lower than or equal to 10, a zero charge point (ZCP) of between 3 and 6.5 and resulting in an aqueous suspension whose pH varies as a function of its electrical conductivity according to the equation  - pH = b - a log (D), in which  a is a constant lower than or equal to 0.6,  b is a constant lower than or equal to 8.5 and (D) represents the electrical conductivity of the aqueous suspension of silica, expressed in microsiemens cm<-><1>. Process for preparing the silica, consisting in reacting a silicate with an acid, thus resulting in a silica suspension or gel, in performing a first aging at a pH higher than or equal to 6 and lower than or equal to 8.5, then a second aging at a pH lower than or equal to 5.0, in separating off the silica, in subjecting it to washing with hot water until it produces an aqueous suspension whose pH measured on a suspension containing 20 % of SiO2 obeys the equation  - pH = d - c log (D> in  which c is a constant lower than or equal to 1.0,  d is a constant lower than or equal to 8.5 and (D) denotes the electrical conductivity of the aqueous suspension of silica, expressed in microsiemens cm<-><1>; and finally in drying it.   Dentifrice composition containing the silica described.
Patent DE-69000566-T2 (DE)
Inventor: DESSAUX CLAUDE
IPC: B66C13/08
Filed: 1990-07-16
Granted: 1993-06-03
Abstract: The device comprises a pulley block body (11) having several lines (25, 26, 27, 28) and several pulleys (12, 13) over which passes a lifting cable (4) forming a block and tackle (15), a grappling element (15) mounted to turn around a vertical shaft (14) and accommodating a hook (9), and electric motorization (16) to drive grappling element (15) in rotation. Pulley (13), over which the cable in the block and tackle passes, serves to drive an electric generator (35) which charges accumulators (36), the latter supplying the electricity needed for motorization (16). The device is applicable to turret slewing cranes and other cable lifting mechanisms.
Patent DE-69003418-T2 (DE)
Inventor: GUSTAVSSON TORD GUSTAV
IPC: D21G3/00
Filed: 1990-03-01
Granted: 1994-03-24
Abstract: A creping doctor (2) for creping a soft paper web (3) off a yankee cylinder (1) is described which comprises a supporting beam (4) disposed close to the envelope surface of the yankee cylinder (1) and provided with an internal space; a doctor blade (6); a doctor holder (5) mounted to the supporting beam (4); means for producing a subatmospheric pressure in the internal space of the supporting beam (4); and a first suction connection (18, 19, 21) connecting the internal space of the supporting beam (4) to an external dust-generating space (7) located between the doctor blade (6) and the soft paper web (3) creped off. According to the invention the internal space of the supporting beam (4) is divided into a first longitudinal suction chamber (24) and a second longitudinal suction chamber (25). Furthermore, there is a second suction connection (40, 42, 43) connecting the second suction chamber (25) of the supporting beam (4) with an internal dust-generating space (8) located between the doctor blade (6) and the envelope surface of the yankee cylinder (1), while the first suction connection (18, 19, 21) connects the external dust-generating space (7) with the first suction chamber (24).
Patent DE-69019361-T2 (DE)
Inventor: SUTHERLAND ROBERT L
IPC: A63C5/00
Filed: 1990-09-28
Granted: 1996-02-08
Abstract: A snow ski (20) for use in soft deep snow, in which the length and width of the ski is selected so as to optimize the surface area in relation to the weigth of the skier using the ski. The ski is also provided with a binding plate (10) to which a normal ski binding may be secured, and which may be adjusted longitudinally on the ski in order to select the proper position of the skier's weight with respect to the length of the ski, and for varying snow conditions.
Patent DE-69022086-T2 (DE)
Inventor: BERRENS LUBERTUS
IPC: A61K39/36
Filed: 1990-03-08
Granted: 1996-02-15
Abstract: Primary-toxic chemical compounds with a molecular weight of less than 12000 Daltons, which may be isolated from plant material and which are, or may become, potential IgE-binding allergens causing immediate-type allergy in predisposed individuals; methods for their isolation and their use for clinical purposes.
Patent DE-69024454-T2 (DE)
Inventor: CASADO MICHEL
IPC: C07D317/46
Filed: 1990-10-08
Granted: 1996-08-08
Abstract: New process for the preparation of 2,2-difluoro-1,3-benzodioxole from 2,2-dichloro-1,3-benzodioxole. More precisely, the invention consists of a process for the preparation of 2,2-difluoro-1,3-benzodioxole by reaction of 2,2-dichloro-1,3-benzodioxole with potassium fluoride in the presence of an effective quantity of a potassium, sodium, caesium, rubidium or quaternary ammonium hydrogen fluoride. 2,2-Difluoro-1,3-benzodioxole is an intermediate compound which is used especially for the preparation of products for agricultural chemistry and for the synthesis of pharmaceutical products.
Patent DE-69118690-T2 (DE)
Inventor: KELLY JAMES
IPC: C12M3/00
Filed: 1991-05-07
Granted: 1997-01-09
Abstract: Permanent cell lines are provided which display liver-specific biological activity at a level effective to support a subject suffering from hepatic failure or insufficiency. The cells find use in treating various liver disorders. An example of the cell lines is HepG2/C3A deposited under ATCC No. CRL-10741. Methods for use of the cells in liver assist devices and methods for producing liver assist devices are also provided.
Patent DE-69131969-T2 (DE)
Inventor: LEWIS RANDOLPH V
IPC: C12P21/02
Filed: 1991-04-18
Granted: 2000-06-15
Abstract: The present invention is directed to isolated cDNA which codes for spider silk protein or a fragment or variant thereof, a replicable vector containing cDNA which codes for spider silk protein and which is capable of expressing spider silk protein, a transformed cell or microorganism containing cDNA which codes for spider silk protein or a fragment thereof which is capable of expressing spider silk protein and products, such as fibers, which may be manufactured utilizing the recombinant protein of the present invention. <IMAGE>
Patent DE-69203803-T2 (DE)
Inventor: MORASSUTTI PAOLO
IPC: E04F13/14
Filed: 1992-01-15
Granted: 1995-11-30
Abstract: PCT No. PCT/EP92/00074 Sec. 371 Date Sep. 14, 1992 Sec. 102(e) Date Sep. 14, 1992 PCT Filed Jan. 15, 1992 PCT Pub. No. WO92/13154 PCT Pub. Date Aug. 6, 1992.The accessory spacing element for dowel anchoring devices for wall covering slabs includes a tubular body made of plastic material which is interposed between the dowel and the respective accommodation seat of the slab. The body has an elastically deformable frustum-shaped annular flange at one end thereof.
Patent DE-69209036-T2 (DE)
Inventor: SAGE JEAN-MARC
IPC: C08L77/10
Filed: 1992-12-21
Granted: 1996-10-02
Abstract: A process for the manufacture of polyamides consisting essentially of the stages of: (i) reacting 10 to 90% by weight of the aliphatic and/or cycloaliphatic and/or aromatic-aliphatic diamines (c) with a lactam and/or corresponding amino acid (a) or the substantially stoichiometric combination of one or more aliphatic diamine(s) and of one or more dicarboxylic aliphatic acid(s) and with the aromatic diacid (b); and (ii) reacting the remainder of the aliphatic and/or cycloaliphatic and/or aromatic-aliphatic diamine (c) with the oligomer produced in stage (i) in one or more substages.