baber/WOPTO huggingface dataset:
Patent EC-SP045505-A (EC)
Title: Nuevos derivados de bencimidazol
Inventor: OTAKE NORIKAZU
IPC: C07D519/00
Filed: 2004-12-22
Abstract: Un compuesto de fórmula (I): (donde A, B, C y D son, de modo independiente, nitrógeno o metino opcionalmente sustituido; E es nitrógeno, metino o metino sustituido con hidroxi; n es 0 ó 1; T, U, V y W son, de modo independiente, nitrógeno o metino opcionalmente sistutuido, X es -N(SO2R4)- , -N(COR5)- o -CO-; Y es -C(R6)(R7)-, -O- o -N(R8) -, con la condición de que se excluya el compuesto (I) cuando E es nitrógeno, n es 0, X es -CO-, e Y es -O-) es útil como agente para el tratamiento de varias enfermedades relacionadas con el NPY, por ejemplo transtornos cardiovasculares tales como angina, insuficiencia cardíaca aguda o congestiva, infarto del miocardio, hipertensión, nefropatía, anormalidad electrolítica, vasoespasmos, arteriosclerosis, etc., trastornos del sistema nervioso central tales como bulimia, depresión, ansiedad, ataque cerebrovascular, epilepsia, demencia, dolor, alcoholismo, privación de fármacos, trastornos del ritmo circadiano, esquizofrenia, deterioro de la memoria, trastornos del sueño, alteración cognoscitiva, etc., enfermedades metabólicas tales como obesidad, diabetes, anormalidad hormonal, etc., trastornos genitales o reproductivos tales como infertilidad, parto prematuro, disfunción sexual, etc., trastornos gastrointestinales, trastorno respiratorio, enfermedades inflamatorias o glaucoma y similares, también por ejemplo aterosclerosis, hipogonadismo, hiperandrogenismo, síndrome ovárico poliquístico, hirsutismo, trastorno de la motilidad gastrointestinal, reflujo gastroesofágico relacionado con la obesidad, hipoventilación por obesidad (síndrome de Pickwick), apnea del sueño, inflamación, inflamación sistémica de la vasculatura, osteoartritis, resistencia a la insulina, broncoconstricción, preferencia por el alcohol, síndrome metabólico, mal de Alzheimer, hipertrofia cardíaca, hipertrofia ventricular izquierda, hipertrigliceridemia, colesterol HDL bajo, trastornos cardiovasculares tales como enfermedad coronaria cardíaca (CHD), enfermedad cerebrovascular, accidente cerebrovascular, enfermedad vascular periférica, muerte súbita, enfermedades de la vesícula biliar, cáncer (de mama, de endometrio, de colon), disnea, hiperuricemia, fertilidad alterda, lumbalgia y mayor riesgo de anestesia.
Patent EC-SP055680-A (EC)
Title: Nuevos compuestos de imidazol como inhibidores del factor de crecimiento transformante (tgf)
Inventor: BLUMBERG LAURA COOK
IPC: C07D401/04
Filed: 2005-03-17
Abstract: Se describen nuevos compuestos de imidazol, incluyendo sus derivados, intermedios para su preparación, composiciones farmacéuticas que los contienen y su uso medicinal. Los compuestos de la presente invención son inhibidores potentes de la ruta se señalización del factor del crecimiento transformante ("TGF)-ß. Son de utilidad en el tratamiento de diversos estados de enfermedad relacionados con TGF incluyendo, por ejemplo cáncer y enfermedades fibróticas.
Patent EC-SP066973-A (EC)
Title: D-homo-17-cloro-16(17)eno esteroides
Inventor: WYRWA RALF
IPC: C07J63/00
Filed: 2006-11-08
Abstract: La invención se refiere a D-homo-17-clor-16(17)-en-esteroides de la fórmula I con actividad andrógena, procedimiento para su preparación y composiciones farmacéuticas que contienen estos compuestos y su uso para preparar medicamentos.
Patent EC-SP099693-A (EC)
Title: Ligandos de receptor vainilloide novedosos y el uso de los mismos para la produccion de farmacos
Inventor: SAUNDERS DEREK
IPC: A61K31/44
Filed: 2009-10-16
Abstract: La presente invención se relaciona a ligandos de receptor vainilloide novedosos de fórmula general (I) un método para la producción de los mismos, el contenido farmacéutico de los compuestos, y el uso de tales compuestos para la producción de fármacos para tratar migrañas, depresión, enfermedades neurodegenerativas, enfermedades cognitivas, desordenes de ansiedad, epilepsia, coágulos, diarrea, pruritos, inflamaciones, desórdenes del sistema cardiovascular, desórdenes alimenticios, dependencia a los medicamentos, uso indebido de medicamentos y en particular incontinencia urinaria.
Patent EC-SP961650-A (EC)
Title: Proteinas anti- obesidad (caso x-9926a)
Inventor: DIMARCHI RICHARD DENNIS
IPC: A61K38/16
Filed: 1996-03-25
Abstract: La presente invención proporciona contra la obesidad proteínas, que cuando se administra a un paciente regular tejido graso. En consecuencia, dichos agentes permiten a los pacientes a superar su desventaja obesidad y vivir una vida normal con mucho menor riesgo de diabetes tipo II, enfermedades cardiovasculares y el cáncer.
Patent EC-SP972105-A (EC)
Title: Virosomas cationicos como sistema de transferencia para material genetico
Inventor: KLEIN PETER
IPC: A61K9/12
Filed: 1997-05-07
Abstract: La presente invención se refiere a un virosoma de carga positiva para el suministro eficaz de material genético a células en reposo o proliferantes de mamíferos in vitro e in vivo. La membrana del virosoma contiene lípidos catiónicos y/o policatiónicos, al menos un péptido de fusión vírica y preferentemente al menos un marcador citoespecífico, seleccionado ventajosamente del grupo formando en anticuerpos monoclonales, fragmentos de anticuerpos F (ab¿)2 y Fab¿, citoquinas y factores de crecimiento, para la detección y unión selectiva de células diana.
Patent EC-SP982382-A (EC)
Title: Derivados de 5- aroilnaftaleno
Inventor: ROTSTEIN DAVID MARK
IPC: A61K31/01
Filed: 1998-01-27
Abstract: El presente invento se refiere a ciertos derivados de 5-aroilnaftaleno de la fórmula I (gráfico), en donde A, Z, R1, R2, y R3 tienen el significado expuesto en la memoria y las reivindicaciones que son inhibidores de prostaglandina G/H sintasa, composiciones farmacéuticas que los contienen, métodos para su empleo y métodos para la preparación de estos compuestos.
Patent FI-20001649-A (FI)
Inventor: ISOTALO LAURI
IPC: H04M3/42
Filed: 2000-07-11
Abstract: The invention relates to a method for providing a service number, subject to a predefined charge, to a mobile subscriber, whose mobile subscription (1) is a visitor in the mobile network of a mobile operator other than the mobile operator with which the mobile subscriber has made a mobile subscription agreement. The invention concerns a method, in which a call connection is created between the customer's mobile station (1) and some second telephone device (15), on the basis of a request sent by the customer. When they desire a connection to some number, the customer sends a fixed-form short message to a number stated by the mobile operator. This short message contains the number to which the customer wishes a connection. Having received the short message, the equipment of the mobile operator calls the customer's mobile station (1). Once the customer has answered the call, the equipment of the mobile operator calls the subscription (15) stated in the customer's short message. Once this call has been answered, the equipment of the mobile operator links the call connections in such a way that a call connection is formed between the customer's mobile station (1) and the desired subscription (15). In the method, billing is carried out in such a way that the possessor of the destination subscription is billed for at least part of the expenses relating to the call connection. The provider of the service number can also be billed for the expenses arising from the call connection request.
Patent FI-20011154-A (FI)
Inventor: KOTAKE MAKOTO
IPC: C07K5/078
Filed: 2001-06-01
Abstract: The present invention relates to a substituted thiazoloÄ3,2-aÜazepine derivative having inhibitory activity against angiotensin I converting enzyme and neutral endpeptidase. The above substituted thiazoloÄ3,2-aÜazepine derivative is represented by the following general formula (I): <CHEM> (wherein R1 represents a hydrogen atom or a protecting group of a thiol group; R2 represents a hydrogen atom, a lower alkyl group, an aryl group which may have a substituent, a hetroaryl group which may have a substituent, a lower alkoxyl group or a lower alkylthio group; R3, R4 and R5 may be the same or different from one another and represent each a hydrogen atom, a lower alkyl group, a lower alkoxyl group, a lower alkylthio group or the like, with the proviso that the case wherein all of R3, R4 and R5 are hydrogen atoms are excepted; R6 and R7 may be the same or different from each other and represent each a hydrogen atom or a lower alkyl group; R8 represents a hydrogen atom or a protecting group of a carboxyl group; and m and m are each independently 0 or, 1 or 2).
Patent FI-20020184-A (FI)
Inventor: BURTON DENNIS R
IPC: C07K16/10
Filed: 2002-01-31
Abstract: PCT No. PCT/US93/08786 Sec. 371 Date Jan. 27, 1994 Sec. 102(e) Date Jan. 27, 1994 PCT Filed Sep. 16, 1993 PCT Pub. No. WO94/06448 PCT Pub. Date Mar. 31, 1994Human monoclonal antibodies and fragments thereof which bind and neutralize respiratory syncytial virus (RSV) antigenic subgroups A and B are disclosed. Also disclosed are diagnostic and immunotherapeutic methods of using the monoclonal antibodies as well as cell lines producing the monoclonal antibodies.
Patent FI-20030575-A (FI)
Inventor: NYGREN KARI
IPC: E04B1/343
Filed: 2003-04-15
Abstract: The invention relates to a lightweight ballistic shelter comprising mutually connectable modular panels of two sizes only (8, 7, 6). Each panel (8, 7, 6) of the shelter structure is connectable to any other panel of the shelter system thus allowing protective structures of different sizes and shapes to be assembled therefrom. The shelter is assembled from planar panels of which at least one (6) has the shape of an equilateral triangle and at least another one (7) has a square shape. The shelter system also includes coupler means (4, 5) for connecting the modular panels (6, 7, 8) with each other. <IMAGE>
Patent FI-20045117-A (FI)
Inventor: KANTOLA JUHANA
IPC: B65G1/04
Filed: 2004-04-02
Abstract: A method, as well as a storage and manipulation system for manipulating and transferring cassettes (8) used for storage, which system comprises a rack (3) for storing cassettes, equipped with supports (12) on which the cassette rests and along which the cassette is transferred, as well as a transfer device (1) which is equipped with: a slide (5), onto which the cassette can be transferred and which can be transferred in the horizontal direction and which is provided with a lifting and lowering movement; and grippers (6, 7) with the function of gripping the cassette and moving it onto or off the slide. The slide is arranged to be placed underneath the front part (8a) of the cassette and, by means of a lifting movement, to elevate the front part of the cassette in such a way that the cassette can be transferred along the slide onto the slide, its rear part (8b) being simultaneously supported by the support of the rack. The slide is also arranged, during the transfer of the cassette into the rack, to lower the front part of the cassette by a lowering movement onto the support of the rack, when the rear part of the cassette is already transferred onto the support of the rack, and to move the cassette further down so that the slide can be moved into the transfer device without restrictions. In an advantageous embodiment, the front part of the cassette is equipped with a roll (10) which, when the cassette is in the rack, is not placed on a support in the rack but is separate from it and whose underside is freely accessible by the slide, wherein the cassette is simultaneously arranged to rest on the support, on a support roll (13) in the rear part of the cassette, and the bottom structure (16) in the front part of the cassette being placed against the support.
Patent FI-20070288-A (FI)
Inventor: WECKMAN ANDERS
IPC: C23F1/30
Filed: 2007-04-13
Abstract: In the method, the spent stripper solution for tin or a tin mixture is treated to precipitate dissolved or suspended metal compounds. On the one hand chemicals for reuse, and on the other hand metals such as copper, tin, lead and/or iron are recovered from the waste water streams. Efficiency of the precipitation is improved by heating of the stripping solution at elevated temperatures, and by the addition of a precipitating reagent. Once the precipitate is removed, the remaining liquid may be reused, typically as an admixture with a fresh solution. In the production method of a regenerated stripping solution for tin comprising at least one inorganic acid, ferric ions, at least one organic acid, and at least one organic additive, the stripping solution is heated at elevated temperatures, precipitating reagent is added, precipitated matter is separated and removed, and one or some of the acids or additives mentioned are added for the recovery of the desired tin stripping capacity.
Patent FR-1131380-A (FR)
IPC: F16L47/22
Filed: 1955-09-22
Granted: 1957-02-20
Abstract: 773,033. Pipe joints. SOC. PER AZIONI LA RESINA. Sept. 14, 1955 [Sept. 25, 1954], No. 26260/55. Class 99(1) In a spigot-and-socket joint having a pipe 1, Fig. 1, of thermoplastic material with a a socket provided at one end-by deformation at an elevated temperature, and a second pipe 3 having a resilient gasket ring 6 around the end which is inserted into the socket, the latter, due to the property of thermoplastic materials to resume their original shape whenever they are heated a second time after deformation at an elevated temperature, is contracted into the pipe 3 and the gasket 6 upon reheating the socket. The pipe 1 of such material, as PVC, has the socket formed by the insertion of a mandrel after softening the pipe end by heat; the pipe 3 is of metal or plastic whilst the gasket 6. is made of rubber. Upon reheating the socket it shrinks on to the pipe 3 as shown in Fig. 2 and presses the gasket 6 radially; the shrinking action may be assisted by applying a, metal sleeve around the bell mouth. Such a joint permits relative axial movement between the pipes without leakage occurring. In a modification, the pipe 1 has a single bell mouth and the pipe 2 is formed with a bulge behind the gasket. In another modification, the pipe 2 is provided with a bell mouth and two spaced gaskets; the pipe 2 may have a number of protrusions of any suitable shape.
Patent FR-1603082-A (FR)
Title: Sewage works
IPC: C02F3/10
Filed: 1968-09-06
Granted: 1971-03-15
Abstract: Sewage treatment plant can be adapted to the requirements of various numbers of users by making use of prefabricated panels and partitions the parts are assembled by means of metallic bonds and cement joints. The cells or compartments are orthogonal and the number employed for settling, digestion and filtration can be altered as required. The filters consist of a thick layer of pozzolana for the oxidation of the organic matter carried by the decanted effluent, the pozzolana is supported by grids which allow of the distribution of fresh air. The decanted effluent is distributed over the filters by an automatic flushing device in the form of an elastic plastic tube. The costs of on-site construction are greatly reduced by the prefabricated units to which the accessory devices can be adapted.
Patent GB-1047240-A (GB)
IPC: A62B17/00
Abstract: 1,047,240. Protective clothing. FEDERAL MINISTER OF DEFENCE, GERMANY.. Dec. 6, 1960 [Dec. 8, 1959], No. 42045/60. Heading A3V. A protective cape and hood are unfolded and spread over the wearer by gas released from an atached flask; this provides rapid and automatic protection against gases, radioactive fall-out and bacteriological aerosols. Fig. 1 shows a cape and hood supported by a network of tubes 5, 6 fed with gas through a header 3 from a flask worn on the back; alternatively cape and hood may be double walled and divided by ribs into cells into which gas is fed. After unfolding the cape, the gas is allowed to escape round the edge of the hood, keeping the atmosphere near the face uncontaminated until a gas mask can be put on; the hood and cape can then be drawn tight. The cape and hood may be of a synthetic resin material alone or as a layer on natural or synthetic fibre material.
Patent GB-1050602-A (GB)
IPC: E02F5/06
Abstract: 1,050,602. Trench digging machines. C. J. DAVIS. May 21, 1965. No. 21667/65. Heading E1F. A trench digging machine comprises a boom carrying an endless digging chain with one or two shaft-mounted auger blades rotatably secured to and extending transversely from one side of the boom at substantially ground level to more excavated earth away from and to one side of the trench. The other side of the boom is fitted with a deflecting plate coacting with the chain to direct the excavated soil toward the auger blade(s). The shaft of the, or each auger blade has a sprocket engaging the chain for rotating the auger blade. The boom has a thrust plate for bearing against the side of the trench to counteract lateral forces resulting from the auger blades.
Patent GB-1050792-A (GB)
IPC: F28F25/10
Abstract: 1,050,792. Cooling towers. D. B. SPALDING. Oct. 1, 1963 [July 3, 1962], No. 25405/62. Heading F4K. A water-cooling tower into which air enters at the bottom of the tower in directions substantially perpendicular to the central vertical axis of the tower and passes upwardly through the packing in the tower for the purpose of cooling water flowing downwardly over the packing, includes an air flow passage defined between the lower surface of the packing and the floor of the tower which is so shaped as to maintain the static air pressure therein substantially uniform at all positions in said passage, thereby providing a uniform velocity of air flow upwardly through the packing over the whole flow cross-section of the tower. In Fig. 3, the air flow passage is defined by the lower surface of a dished packing 6 and the surface of the pond 5, the central part of the packing being adjacent to or in contact with the water surface of the pond. Air passes inwardly and upwardly through the packing with a substantially uniform radial velocity. The water distributer 3 may, as shown, be positioned at the highest level of the packing, the sprayers (not shown) being carried above the same, or alternatively the distributer may be arranged just above the curved upper surface of the packing (Fig. 5, not shown), or the distributers may be at two different levels (Fig. 6, not shown). The packing may be in horizontal layers so supported on the grid of beams as to form an approximate cone-shape (Fig. 4, not shown). In Fig. 7, the packing 2 is horizontal, the water distributer 3 is positioned just above the same, and an annular pond surrounds a dome-shaped base 10. In a further arrangement the dome shape base may comprise a light screen of sheets of asbestoscement &c. arranged above the pond (Fig. 8, not shown). The packing may be of the wooden splash-bar type 13 (Fig. 9, not shown), or of corrugated material.
Patent GB-1054608-A (GB)
IPC: F04D29/54
Abstract: 1,054,608. Compressor blades. ROLLS-ROYCE Ltd. Sept.16, 1965, No.39640/65. Heading F1T. A stator blade assembly, e.g. for the compressor of a gas turbine vertical lift engine comprises a row of blades 18 formed at least partly of a synthetic resin material such as laminated epoxy resin reinforced with glass fibre and mounted in a frusto-conical casing member 16 which may be of titanium. A single turn of a securing band 24 (preferably in the form of tape or filament of a synthetic resin material reinforced with glass) is wound circumferentially around the casing member 16 and bonded to it, and holes 19 are then formed. The stator blades 18 are then inserted in the holes 19 and bonded therein with synthetic resin material. Slots 23 are then cut in the blade roots 21 by one machining operation, the cutting tool skimming the surface of the single turn of the band 24. Further turns of the band 24 are then wound through the slots so as to fill the full depth of the slots and are then secured in place preferably by bonding to the roots 21 and casing member 16 by a synthetic resin material.
Patent GB-1095338-A (GB)
IPC: A62C3/06
Abstract: 1,095,338. Preventing and extinguishing fires. H. V. WILLIAMS, T. J. ROCHESTER and I. H. ROWNEY. June 10, 1966 [July 14, 1965], No. 29788/65. Heading A5A. Apparatus for preventing or extinguishing a fire in a storage tank, for example, inflammable liquids comprises perforated tubing placed in the lower part of the tank and communicating with the outside of the tank, non- return valve(s) in the tubing preventing escape of the tank contents, and means extending from the tubing to a point remote from the tank which provides a source of pressurised fire extinguishing gas. The perforated tubing may face downwards, spaced at least 18 inches from either the floor of the tank or from any water layer on the floor of the tank. Suitable gases are carbon dioxide, or bromochloro-difluoromethane pressurised with nitrogen.
Patent GB-1225310-A (GB)
IPC: B32B17/10
Filed: 1968-12-06
Abstract: 1,225,310. Laminated glass. NIPPON SHEET GLASS CO. Ltd. 6 Dec., 1968 [7 Dec., 1967], No. 58121/68. Heading B5N. A laminate comprises at least two transparent sheets of glass and an interlayer of an organic polymeric material interposed between adjacent glass sheets and bonded thereto to provide a unitary structure, characterized by at least one of said adjacent glass sheets having a reduced strength due to pre-treatment of its surface. In the pretreatment, any chemical or mechanical method of decreasing the strength of glass may be used. In an embodiment, each of two glass sheets have one pretreated surface and one non-treated surface and the interlayer is interposed between the pretreated surface of one glass sheet and the non-treated surface of the other glass sheet.
Patent GB-1225383-A (GB)
IPC: B65D5/43
Filed: 1968-04-29
Abstract: 1,225,383. Containers; boxes; packages. K. KLEIN, [trading as HASSIA VERPACKUNG. KARL KLEIN]. 29 April, 1968 [28 April, 1967 ; 21 Sept., 1967], No. 20247/68. Headings B8C, B8D and B8P. A container has an opening for access to the contents which is closed by a flap of a stiff sheeting material, such that the flap bears on a plane wall portion of the container and is joined thereto by one or more tear-open adhesive or heat-sealed joints. In a first embodiment, the container 31 is deep-drawn from thermoplastics sheeting and has an upstanding edge joined by heat-sealing or adhesive fixing to a cover 33 made of cardboard. An opening 34 for access to the contents is provided in the cover. A flap 35 is joined by hinging to the cover 33, closes the access opening when it is swung down and is retained in closed position by an adhesive spot 36. After tearing the adhesive joints, reclosure is effected by insertion of a tongue on one corner of the flap into the slot 37. The access opening, tongue and slot may be differently arranged relative to one another (Fig. 2; not shown). In a second embodiment, the container may be formed from a folded blank (Fig. 3) with two broad sides 1, 2, two longitudinal narrow sides 3, 4, a flap 5, pairs of extensions 6, 8 and 7, 9, and further extensions 10, 11. A recess 12 is provided inside 1 for access to the contents. The adhesive joins are in the form of two surface zones 15, 16 and are each bounded by an annular incision which does not penetrate completely through the material of the flap. The blank is first folded into a tube by the formation of the adhesive joins 15, 16 (Fig. 4, not shown) and the extensions 6, 8 are folded over the extension 10 and adhesively joined to each other to form an end face. The extensions 11, 7 and 9 are similarly treated after insertion of the contents. The container is opened by tearing the adhesive joins 15, 16 whereupon those portions (17) of the flap bounded by the annular incisions remain (Fig. 5, not shown) on the broad side 1 and serve to indicate that the container has been opened. Alternatively, a single adhesive zone 18 (Figs. 7, 8, 9, not shown) bounded by an annular incision 19 which penetrates the flap and is separated from it by thin webs 20 may be provided. Upon tearing open the adhesive join, the webs are severed and the full material thickness of the zone remains on the wall 1 (Fig. 10, not shown). Subsequent reclosure (Fig. 11, not shown) is made more secure by the engagement of the zone with the hole 21.