baber/WOPTO huggingface dataset:
Patent CA-3090592-A1 (CA)
Title: Plate-forme car-t allogenique utilisant une banque de cellules souches pluripotentes induites correspondant au systeme hla, et compositions, systemes et procedes associes
Inventor: SMITH ROBIN Y
IPC: C12N5/0789
Filed: 2018-03-14
Abstract: L'invention concerne des systèmes et des procédés de production de compositions de CAR-T « universelles » et/ou « standard » appropriées pour une thérapie anticancéreuse à administrer à un ou plusieurs individus. Une composition de CAR-T est une composition comprenant un ou plusieurs types de lymphocytes T à récepteurs antigéniques chimériques (CAR-T). Les cellules souches pluripotentes induites (iPSC) et/ou les lignées cellulaires, et des compositions de CAR-T dérivés d'iPSC quelconques dérivées de celles-ci, sont identifiées comme étant compatibles avec un ou plusieurs individus à l'aide d'une identification d'un type de cellule indiquant une compatibilité (par exemple, une correspondance au système HLA et/ou une correspondance au système ABO et/ou une correspondance au système Rhésus). Les cellules compatibles sont ensuite récupérées d'un référentiel géré à indexation HLA (et/ou indexé autrement) ou sont dérivées d'un échantillon biologique d'un donneur. Les cellules compatibles récupérées sont ensuite utilisées pour dériver des compositions de CAR-T dérivés d'iPSC, les compositions dérivées étant appropriées pour une thérapie d'un ou plusieurs individus.
Patent CA-3090926-A1 (CA)
Inventor: THOMPSON CHAD
IPC: F16L1/11
Filed: 2020-08-24
Abstract: An integrated access box for providing surface access to a curb box or other structure, and tracer wires in a single unit. The integrated access box generally includes a body having a first end and a second end and a first chamber (e.g., a curb box chamber or cleanout chamber) extending into the first end toward the second end of the body. The body may be substantially cylindrical in shape, and may include a first opening near the first end of the body and a first chamber access opening in the first chamber near the top of the body, and a tracer wire chamber extending into the body. The tracer wire chamber includes a second opening near the first end of the body. The integrated access box may further include a tracer wire access opening in the tracer wire chamber near the top of the body.
Patent CA-3095486-A1 (CA)
Inventor: KULAKOVSKIJ KIRILL
IPC: B01D46/10
Filed: 2020-10-06
Abstract: What is claimed is an air filtration system (1) for cleansing an air flow containing suspended particles, having a protective mask (2) for wearing on a user's face with a seal (3) positioned at least partly along its edges, at least one first flow channel (6) with a first inlet and a first exit aperture (11,21) and a first air filter (16), and at least one second flow channel (7) with a second inlet and a second exit aperture (12,22) and a second air filter (17).  The filtration system (1) has a blower (10), which is positioned exclusively in the first flow channel (6), for creating an air flow in the first flow channel (6), a control unit (18) for controlling the operation of the blower (10), an electrical supply unit (19), and a discharge unit (5) for discharging excess air pressure from under the mask (2) during the use thereof. The second exit aperture (22) of the second flow channel (7) is positioned in direct proximity to the first exit aperture (21) of the first flow channel (6). The first and second flow channels (6,7), the control unit (18) and the electrical supply unit (19) are positioned in a single casing (4), which is mounted in the upper part of the protective mask (2) and is the only element securing the mask (2) on the user's head.
Patent CA-3096793-A1 (CA)
Title: Filtering cable
Inventor: HAN YUNAN
IPC: H03H7/24
Filed: 2019-06-19
Abstract: The present application discloses a filtering cable, which solves the problem that the cable in the related art cannot ensure a simple and reasonable structural design while having good filter performance. One or several core wires and N defective conductor layers surrounding the core wires are sequentially provided from inside to outside in the cross section in the radial direction of the filtering cable; wherein the defective conductor layer has an etching pattern; the etching pattern is distributed in the axial direction of the filtering cable;  the etching pattern is used to make the filtering cable equivalent to a preset filter circuit to filter the signal transmitted in the filtering cable.
Patent CA-3096897-A1 (CA)
Inventor: IOFFE LEV
IPC: G06N10/00
Filed: 2019-04-19
Abstract: A quantum computer architecture employs logical qubits that are constructed from a concatenation of doubly periodic Josephson junction circuits. The series concatenation of the doubly periodic Josephson junction circuits provides exponential robustness against local noise. It is possible to perform discrete Clifford group rotations and entangling operations on the logical qubits without leaving the protected state.
Patent CA-3098023-A1 (CA)
Inventor: IMMORDINO JR SALVATORE C
IPC: F16B15/00
Filed: 2019-05-10
Abstract: A fastener (10) is provided and is configured for securing magnetized items (52) to a wall board panel (12). Included on the fastener (10) is a fastener body (16) having a first side (18) and an opposite second side (20), and a counter-sunk through-bore (22) extends from the first side (18) to the second side (20). The body (16) has a tapered peripheral edge (26). In addition, the first side (18) is covered with wallboard joint tape (28).
Patent CA-3103150-A1 (CA)
Title: Biomarqueurs proteiques pour la nephropathie et leurs applications
Inventor: CHEN CHAO-JUNG
IPC: G01N33/68
Filed: 2019-06-21
Abstract: La présente invention concerne un biomarqueur, un procédé et un kit de dosage pour identifier et cribler une néphropathie, en particulier une néphropathie diabétique, chez un sujet en ayant besoin, ou prédire une néphropathie diabétique ou un risque précoce de déclin progressif de la fonction rénale (ERFD) chez un patient diabétique.
Patent CA-3106659-A1 (CA)
Title: Surgical training apparatus, methods and systems
Inventor: STONE JONATHAN
IPC: G09B9/00
Filed: 2019-07-18
Abstract: Surgical training apparatus, methods and systems which allow surgical trainees to practice surgical skills on anatomical models in a realistic manner with an augmented reality headset and delivery of targeted surgical coursework curriculum correlated to the actions of the trainee as sensed by sensors in or adjacent the model to help the trainee develop proper surgical technique and decision making.
Patent CA-3106817-A1 (CA)
Inventor: RUFF MICHAEL
IPC: A61P25/08
Filed: 2019-07-09
Abstract: L'invention concerne un procédé de traitement d'attaques, de crises d'épilepsie ou de perte de fonction cérébrale chez un individu, comprenant les étapes consistant à préparer une composition constituée d'un peptide entièrement constitué d'acides aminés D et d'un support pharmaceutiquement acceptable. Le peptide D présente la structure générale : A-B-C-D-E dans laquelle A représente Ser, Thr, Asn, Glu, Ile. B représente Ser, Thr, Asp, Asn, C représente Thr, Ser, Asn, Arg, Lys, Trp, D représente Tyr et E représente Thr, Ser, Arg, Gly. Et tous les acides aminés présents dans le peptide D présentent la configuration stéréoisomérique D et ladite composition peptidique est administrée à une dose thérapeutiquement efficace, ladite composition servant à supprimer l'inflammation sous-jacente à la perte de fonction cérébrale. Le peptide D peut être estérifié, glycosylé ou amidé au niveau de E pour améliorer la distribution tissulaire en favorisant la sortie à partir de la circulation et la pénétration dans le foie.
Patent CA-3111593-A1 (CA)
Inventor: LEAVITT DOUGLAS
IPC: A47K3/00
Filed: 2019-09-19
Abstract: A walk-in bath comprising a sidewall and a door; wherein the door is configured to be in an open position or a closed position, the sidewall and closed door define a tub configured to hold bathing water, the door comprises a fin configured to be grasped by a bather, and the fin comprises a continuous projection positioned on a top edge of the door between a first end of the door and a second end of the door.
Patent CA-3112268-A1 (CA)
Title: Indole-oxadiazole compounds and their therapeutic use
Inventor: GREIG IAIN ROBERT
IPC: A61K31/4245
Filed: 2019-09-12
Abstract: The present application pertains to methods of using indole-oxadiazole compounds of Formula I to modulate cannabinoid receptor activity: I In particular diseases, disorders or conditions that benefit from modulating cannabinoid receptor activity, such as non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), schizophrenia, bipolar disorder, psychosis, metabolic syndrome, type-2 diabetes, dyslipidaemia, obesity, eating disorders, cardiovascular diseases and disorders, and other conditions as described herein, may be treated. Also included in the present application are certain novel compounds of Formula Ia and pharmaceutical compositions comprising these compounds.
Patent CA-3118953-A1 (CA)
Inventor: WU XIAO YU
IPC: A61K9/70
Filed: 2019-11-08
Abstract: Une composition pour prévenir ou traiter l'hypoglycémie chez un patient en ayant besoin a un microgel qui comprend des polymères réticulés contenant des fractions sensibles au glucose ; et un agent thérapeutique augmentant le glucose sanguin chargé sur ou à l'intérieur du microgel. Le microgel comprend en outre l'un quelconque ou une combinaison d'un composant stabilisant et d'un composant d'aide au chargement pour l'agent thérapeutique augmentant le glucose sanguin. Les polymères contenant les fractions sensibles au glucose forment des réticulations secondaires en réponse à un faible taux de glucose, ce qui provoque un rétrécissement du microgel et une libération rapide de l'agent thérapeutique augmentant le glucose sanguin. La composition peut être utilisée pour préparer un timbre à micro-aiguilles composite pour prévenir ou traiter l'hypoglycémie, la composition étant incorporée ou intégrée à l'intérieur d'un réseau de micro-aiguilles du dispositif de timbre à micro-aiguilles.
Patent CA-3119106-A1 (CA)
Title: Disposable hygienic and anti-allergenic pillow protector
Inventor: CHEANG KUAN HOI
IPC: A47G9/02
Filed: 2021-05-18
Abstract: A method of making a hygienic disposable pillow protector involves a step of folding a pillow protector material to define a first surface and a second surface, and to also define a closed end and an open end that is opposite the closed end. The pillow protector material is aligned to further define two unsealed edges. The method then involves sealing the unsealed edges of the pillow protector material by ultrasonic welding or bonding to define two sealed edges extending from the closed end to the open end to thereby define an opening sized to enable insertion of pillow into the disposable pillow protector. The method then involves applying a first strip of double-sided adhesive tape and applying a second strip of double-sided adhesive tape. A pillow may inserted into the disposable pillow protector and the opening sealed by forming folded seams with the first and second strips of tape.
Patent CA-3120263-A1 (CA)
Title: Method for producing food
Inventor: KUBOTA JUNPEI
IPC: A23L13/40
Filed: 2019-11-26
Abstract: Provided is a method for producing a food, the method comprising: a step for obtaining a mixture for an outer layer by mixing a food material with one or two ingredients (A) selected from the group consisting of ingredient (A1) and ingredient (A2); a step for obtaining a mixture for an inner layer by mixing food materials; and a step for obtaining a food composition by covering the mixture for the inner layer with the mixture for the outer layer. The ingredient (A1) is a starch composition that satisfies conditions (1)-(3). condition (1): the starch content is 75 mass% or higher; condition (2): comprising 3-45 mass% of depolymerized starch having 5 mass% or higher amylose content, and the peak molecular mass of the depolymerized starch is from 3X103 to 5X104; and condition (3): the degree of swelling in cold water at 25°C is 5-20. The ingredient (A2) is a pregelatinized starch.
Patent CA-3122551-A1 (CA)
Title: Instruments, guides and related methods for total ankle replacement
Inventor: DOGUE JOSEPH
IPC: A61B17/15
Filed: 2019-12-13
Abstract: Instruments, guides, systems and related methods for total ankle prostheses are disclosed. The instruments, guides, systems and related methods facilitate preparation of a tibia and/or talus of a patient for implantation of a total ankle prosthesis therein. The instruments, guides, systems and related methods also facilitate selection of a particular size of a tibial component, a talus component and/or a tibial insert of the total ankle prosthesis that suits the patient. The instruments, guides, systems and related methods include a tibial trial component, a talar trial component and tibial insert trial component that replicate one or more aspects of the tibial component, the talus component and the tibial insert, respectively, of the total ankle prosthesis. The talar trial component includes an articulation surface that articulates with the tibial insert trial component, and slots that facilitate chamfered resection of the patient's talus for the implantation of the talus component thereon.
Patent CA-3122705-A1 (CA)
Title: Formulations pharmaceutiques a base d'eau de composes de 1,2-dihydropyridine
Inventor: HIRD GEOFFREY S
IPC: A61K9/00
Filed: 2019-12-16
Abstract: La présente invention concerne une formulation pharmaceutique aqueuse d'un agent solubilisant avec un composé de pyridone qui est utile en tant qu'inhibiteur pour des récepteurs non NMDA, en particulier pour le récepteur AMPA. Dans certains modes de réalisation, le composé de pyridone est sursaturé en solution aqueuse à un pH compris entre 6 et 8. Les formulations sont particulièrement utiles en tant qu'injections intraveineuses.
Patent CA-3124176-A1 (CA)
Title: Process for preparing pellets for firing an industrial furnace
Inventor: JENNISSEN LARS
IPC: C10L5/46
Filed: 2019-12-18
Abstract: The invention relates to a method for producing pellets which are capable of providing free flowing powder suitable for firing an industrial furnace from municipal and/or other waste, the process comprising the following steps: (i) providing waste material comprising one or more thermoplastic material(s) of more than 40%, based on the total dry weight of the waste and one or more cellulosic material(s) of more than 30%, based on the total dry weight of the waste, wherein the waste has a particle size distribution with more than 80% larger than 5 mm, more than 95% smaller than 60 mm, (ii) subjecting the waste material through a pelletiser with holes between 4-16 mm and a length ratio of more than 2, and subjecting the pellets through a second pelletiser with holes between 4 and 10 mm, and a length ratio of more than 2 to provide pellets with a diameter between 4 and 10 mm, and a length of between 3 and 50 mm. The invention also relates to pellets obtained and having advantageous properties.
Patent CA-3126261-A1 (CA)
Inventor: GILL AARON MICHAEL
IPC: A47J36/00
Filed: 2018-08-09
Abstract: ABRÉGÉ : Il est décrit un système de cuisson pour cuire des aliments, le système comportant un logement ayant un intérieur creux, un couvercle mobile par rapport au logement, et au moins un élément chauffant associé au logement ou au couvercle, le système pouvant être utilisé dans plusieurs modes, comme un mode de cuisson par conduction et un mode de cuisson par convection, le système pouvant être utilisé pour la cuisson par conduction en mode de conduction et la cuisson par conduction en mode de conduction. Date reçue / Date Received 2021-01-28
Patent CA-3128750-A1 (CA)
Title: Stackable cutlery
Inventor: RAU ROBERT WILLIAM
IPC: A47G21/00
Filed: 2021-08-23
Abstract: A stackable cutlery utensil includes a utensil portion and a handle portion. The handle portion has opposing first and second ends, with the second end being adjacent the utensil portion. The handle portion further has opposing upper and lower surfaces. First and second protrusions project from the lower surface. A recess is included on the upper surface.
Patent CA-3131869-A1 (CA)
Inventor: PRODANOVIC RADOVAN
IPC: H04W12/069
Filed: 2021-09-23
Abstract: A communication system mitigating the risk of an incoming spoofed collet. The method involves issuing a token or a digital certificate to each network connection of a user, such as to each member of a social media platform to which the user is connected. The method includes determining a vanditv of the token or certificate of the network connection with a receiving party, which may be performed in resp(mse to searching and identifying the receiving party by a calling pany. The method includes transmitting a rnessage ro the receiving party by the calling party in response to the validity confirmation of the token or the digital certificate.  A message is transrnitted that includes a calling identifier to be displayed to provide calling lr) to the receiving party and a time of the intended call. The message may provide connection details, mutual connections, and historical events with the calling party.
Patent CA-3132190-A1 (CA)
Title: Dispositif de serrage de coffrage pour coulage vertical
Inventor: FARESIN CHIARA
IPC: E04G11/06
Filed: 2020-03-11
Abstract: L'invention concerne un dispositif de serrage (1) destiné à un coffrage pour coulage vertical, comprenant un premier corps et un second corps (10, 20) conçus pour être accouplés de manière coulissante l'un à l'autre, le premier corps (10) comprenant un élément allongé (11) qui s'étend principalement le long d'un premier axe (100) et ayant une première mâchoire (12) au niveau d'une première extrémité, le second corps (20) comprenant une partie de base sensiblement creuse (21) qui peut être liée de façon coulissante à l'élément allongé (11) et qui a une seconde mâchoire (22), des moyens (30) de verrouillage étant prévus pour verrouiller mutuellement les premier et second corps (10, 20) de manière à serrer mutuellement au moins deux composants (51, 61) entre les première et seconde mâchoires (11, 22).
Patent CA-3132942-A1 (CA)
Title: Extension set to reduce extension tube kinking
Inventor: NAIDU JITHENDRA KUMAR SATHYANARAYANA
IPC: A61M5/158
Filed: 2020-04-07
Abstract: A vascular access system may include a catheter adapter and an extension set. The extension set may include a first end having a first connector coupled to the catheter adapter, a second end having a second connector, an extension tube disposed between the first end and the second end, and a brace configured to hold the extension tube in a curved position. The extension set may alternatively include a housing disposed between the first connector and the extension tube, where the housing is U-shaped or V-shaped and a fluid pathway extends through the housing.
Patent CA-3141626-A1 (CA)
Title: Novel il-15 prodrugs and methods of use thereof
Inventor: LU YUEFENG
IPC: C12N15/62
Filed: 2020-06-12
Abstract: Provided herein are IL-15 cytokine prodrugs and methods of making and using thereof.
Patent CA-3143288-A1 (CA)
Title: Switched reluctance machines without permanent magnets
Inventor: POPOV ANDREI
IPC: H02K16/02
Filed: 2020-06-26
Abstract: Disclosed are various embodiments for switched reluctance machines having a rotor comprising a plurality of rotor core assemblies configured to form a reluctance torque tunnel having at least a first reluctance tunnel segment and a second reluctance tunnel segment and a stator having a plurality of coils configured to form a coil winding assembly, the coil winding assembly positioned within the reluctance torque tunnel, such that at least one of the plurality of coils is surrounded by the first reluctance tunnel segment or the second reluctance tunnel segment, alternatively the rotor may be the coil winding assembly and the stator may be the reluctance torque tunnel.
Patent CA-3143297-A1 (CA)
Title: Surgical suture tensioning and labeling
Inventor: CORTEZ FELINO V
IPC: G09B23/28
Filed: 2020-11-30
Abstract: A method of managing suture deployment onto a target organ tissue involves applying a label to a first portion of a first suture extending externally from a target organ, the first suture having a second portion deployed onto the target organ tissue within the target organ. The method further involves attaching a suture tab to the first portion or another portion of the first suture extending externally from the target organ, and applying tension to the first suture, wherein applying tension to the first suture comprises coupling the first suture to a tension guide and determining whether the tension is within a target range.
Patent CA-3143307-A1 (CA)
Title: Provision of remote application action feed cards
Inventor: Xu sai
IPC: H04L9/08
Filed: 2020-06-10
Abstract: Described embodiments provide systems and methods for providing remote application action feed cards. A ticket can be received from a client device. The ticket can be indicative of an action of a remote application and the remote application can be accessible by a group of users. The device can receive information about the action identified in the received ticket from at least one user of the group of users in response to provision of a determined key and the received ticket to the group of users. The device can provide the received information to client devices of user of the group of users to identify actions of other users of the group of users.
Patent CA-3144734-A1 (CA)
Inventor: ESCOBAR-CABRERA ERIC
IPC: C12N15/13
Filed: 2021-05-20
Abstract: Heterodimeric Fc variants comprising one or more asymmetric amino acid mutations in the CH2 domain and having increased selectivity of binding to Fc?RIIb as compared to a parental Fc region, polypeptides comprising the heterodimeric Fc variants and polynucleotides encoding the heterodimeric Fc variants. The one or more asymmetric mutations comprise replacement of a loop in the CH2 domain, a mutation at position 236 in the CH2 domain, or a combination of replacement of a loop in the CH2 domain and a mutation at position 236 in the CH2 domain.
Patent CA-3144945-A1 (CA)
Title: Pharmaceutical composition
Inventor: SATO TAKASHI
IPC: A61K9/14
Filed: 2020-01-10
Abstract: A pharmaceutical composition that is characterized by including particles that include a water-soluble base material and a poorly water-soluble compound, wherein the water-soluble base material includes a rapidly water-soluble compound, and the poorly water-soluble compound is a kinase inhibitor and is present within the water-soluble base material in an amorphous condition.
Patent CA-3145600-A1 (CA)
Inventor: FUJIO YOSHIHIKO
IPC: B65G35/06
Filed: 2014-03-28
Abstract: An article transport facility is provided which can allow transport carriages to travel with sufficient stability while avoiding damages to any transport carriage when the connection to another adjacent transport carriage is disengaged. Each of a plurality of transport carriages, which forms a carriage sequence, includes a carriage main body (6), a wheel (8) which rolls on a travel surface (26a) formed along the travel path, a first connecting portion (10) provided to a forward end portion of the carriage main body (6), and a second connecting portion (11) provided to a back end portion of the carriage main body (6). And the first connecting portion (10) is connected to the second connecting portion (11) of another transport carriage that is immediately in front so as to be pivotable about a carriage pivot axis (P1) extending along a vertical direction. The wheel (8) is provided in the forward end portion of the carriage main body (6). And the wheel (8) and the carriage pivot axis (P1) of the first connecting portion (10) overlap with each other as seen along a carriage lateral direction.