baber/WOPTO huggingface dataset:
Patent AU-2006275415-B2 (AU)
Title: Compositions and methods for monitoring and altering protein folding and solubility
Inventor: DELISA MATHEW P
IPC: C07H21/00
Filed: 2006-07-31
Granted: 2011-07-21
Abstract: The present invention relates to the fields of microbiology, molecular biology and protein biochemistry. More particularly, it relates to compositions and methods for analyzing and altering (e.g., enhancing or inhibiting) protein folding and solubility.
Patent AU-2006331357-B2 (AU)
Title: Compositions and methods for synthesizing novel heterocyclic therapeutics
Inventor: RENIA LAURENT
IPC: A61P31/18
Filed: 2006-12-28
Granted: 2012-05-17
Abstract: Methods for the synthesis of various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds (I) and their pharmaceutically acceptable salt derivatives are provided. The compounds of the invention are claimed and are useful as medicaments for the treatment or prevention of disease in a mammal, for example a human. In particular the compounds are useful as immuno therapeutics and anti -microbial drugs or vaccines. These heterocyclic derivatives can be used as an active agent in a pharmaceutical, as well as a diagnostic utility.
Patent AU-2007215306-B2 (AU)
Title: Method and apparatus for generating sparged, electrochemically activated liquid
Inventor: FIELD BRUCE F
IPC: B08B3/02
Filed: 2007-02-08
Granted: 2013-01-10
Abstract: A method and apparatus are provided for generating a sparged electrochemically activated liquid (51, 52, 55, 71, 160, 160A, 160B, 190, 192). The apparatus (62, 100, 150, 300, 370, 380, 400, 500, 600) includes a sparging device (50, 161, 163, 325, 326, 503, 505, 603, 605) and a functional generator (10, 40, 162, 324, 504, 604). The functional generator (10, 40, 162, 324, 504, 604) is in fluid communication with the sparging device (50, 161 , 163, 325, 326, 503, 505, 603, 605) and includes an anode chamber (24) and a cathode chamber (26) separated by an ion exchange membrane (27, 43).
Patent AU-2007281911-B2 (AU)
Title: Inhibitors of pyruvate kinase and methods of treating disease
Inventor: CANTLEY LEWIS C
IPC: A61K31/4184
Filed: 2007-08-06
Granted: 2014-02-06
Abstract: The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity.
Patent AU-2007305450-B2 (AU)
Title: Polyester compositions, methods of manufacturing said compositions, and articles made therefrom
Inventor: ADKINS LEONE SHAUN
IPC: C08G63/12
Filed: 2007-09-24
Granted: 2011-12-08
Abstract: Crosslinked polymer compositions have backbones with first and second divalent saturated aliphatic moieties, a divalent saturated aliphatic secondary alcohol moiety, and a trivalent saturated aliphatic moiety. Hydrolytically labile ester bonds joined together these moieties. These polyesters may be polycondensation reaction products of a diol, a triol and a diacid. A molar ratio of the first divalent saturated aliphatic moiety, the divalent saturated aliphatic secondary alcohol moiety, and the trivalent saturated aliphatic moiety to the second divalent saturated aliphatic moiety is in the range of about 0.85 to about 1.5. Preferably, these polyesters are non-cytotoxic, biocompatible, bioabsorbable, or exhibit shape memory behavior with at least one transition temperature of greater than about 30 0C and less than about 100 0C and most preferably exhibit each of these qualities. The compositions may be adapted for a wide variety of uses, including medical applications.
Patent AU-2007306139-B2 (AU)
Title: Combination therapy
Inventor: BROWN JILL
IPC: A61K39/00
Filed: 2007-10-11
Granted: 2014-02-27
Abstract: The invention provides a method of treating neoplastic disease in a subject, said method comprising the simultaneous, sequential or separate, administration to said subject of an effective amount of (i) an inhibitor of a first EGF, e.g. HB-EGF and (ii) an inhibitor of a second EGF, e.g. AREG. Also described are novel synergistic combinations of of EGF inhibitors with topoisomerase inhibitors which attenuate tumour cell growth. Further described are novel anti AREG antibodies.
Patent AU-2007311019-B2 (AU)
Title: Diclofenac gel
Inventor: KISAK ED
IPC: A61K47/36
Filed: 2007-10-17
Granted: 2013-05-16
Abstract: The present invention provides a gel formulation comprising diclofenac sodium which has superior transdermal flux properties, which may be used for the topical treatment of pain, such as in osteoarthritis.
Patent AU-2007324509-B2 (AU)
Title: Novel antiproliferation antibodies
Inventor: BES CEDRIC
IPC: A61K39/395
Filed: 2007-11-23
Granted: 2013-01-17
Abstract: The present invention relates to novel isolated antibodies, or the derived compounds or functional fragments of same, capable of inhibiting the proliferation of tumor cells
Patent AU-2008200973-B2 (AU)
Title: Sales transaction hub
Inventor: CHRIS CAPADOUCA
IPC: G06Q30/00
Filed: 2008-02-29
Granted: 2011-11-03
Abstract: In a computer-implemented method for processing a sales transaction, an un audited sales transaction is received from a sale generator, and temporarily stored in a memory location and forwarded to a transaction auditor to audit the sales transaction and 5 to a plurality of backend processors to begin processing the sales transaction. An audited sales transaction is received from the transaction auditor, where the audited sales transaction is an audited version of the un-audited sales transaction. The audited sales transaction is correlated with the un-audited sales transaction using the temporarily stored un-audited sales transaction, and a resultant sales transaction that includes information 10 from the audited sales transaction is generated. The resultant sales transaction is transmitted to the plurality of backend processors to continue processing the sales transaction. =C, CD c 1 7 T C = S U) 0 0 0 (A 0 0 CCO -4 00 CDl (A CA (A 0 0 0 CDm CD (D (D (D C/) Cl)/l CACA C/) CD C - ------ A
Patent AU-2008206486-B2 (AU)
Title: Tetrahydrobiopterin prodrugs
Inventor: SZCZEPANSKI STEVEN W
IPC: A61P3/00
Filed: 2008-01-09
Granted: 2013-04-18
Abstract: Disclosed herein are analogs of tetrahydrobiopterin, compositions containing the same, and methods of treating an individual suffering from a condition responsive to tetrahydrobiopterin by administration of the analog. These analogs are contemplated for use wherever tetrahydrobiopterin is currently used to treat conditions responsive to tetrahydrobiopterin therapies.
Patent AU-2008220162-B2 (AU)
Title: Coating composition and photochromic optical article
Inventor: MORI KATSUHIRO
IPC: C09D7/61
Filed: 2008-02-21
Granted: 2013-02-21
Abstract: Disclosed is a coating composition which enables to form a hard coat layer having excellent transparency and abrasion resistance on the surface of an optical base such as a plastic lens with high adhesion. Specifically disclosed is a coating composition composed of a silica fine particle (a) having a particle size of not more than 30 nm, an organosilicon compound component (b) containing an epoxy group-containing organosilicon compound (b1) and a tetraalkoxysilane (b2) at a mass ratio (b1/b2) of 0.25-4.0, water (c) and a curing catalyst (d) composed of a complex having aluminum as the center metal. This coating composition contains 15-55 parts by mass of the silica fine particle (a), 30-200 parts by mass of the water (c) and 0.1-5.0 parts by mass of the curing catalyst (d) when the total of the silica fine particle (a) and the organosilicon compound component (b) is taken as 100 parts by mass.
Patent AU-2008254774-B2 (AU)
Title: Treatment of synucleinopathies
Inventor: CULLEN VALERIE
IPC: A01N43/62
Filed: 2008-05-16
Granted: 2013-11-14
Abstract: This invention relates generally to treating synucleinopathies in subjects that are not clinically diagnosed with a lysosomal storage disease, as well as associated methods of making medicaments and screening methods.
Patent AU-2008282152-B2 (AU)
Title: Human antibodies to human CD20 and method of using thereof
Inventor: STEVENS SEAN
IPC: A61K39/395
Filed: 2008-07-31
Granted: 2013-12-19
Abstract: A human antibody or antigen-binding fragment of an antibody that specifically binds human CD20 and is capable of inducing complement dependent cytotoxicity (CDC), and is capable of increasing symptom free survival time between about 2-fold to about 9-fold or more, relative to control-treated animals in a mouse model of human lymphoma. The antibody or antigen-binding fragment thereof is useful in a therapeutic method for treating a CD20-mediated disease or condition, such as for example, non-Hodgkin's lymphoma, rheumatoid arthritis, systemic lupus erythematosus, Crohn's disease, chronic lymphocytic leukemia, and inflammatory diseases.
Patent AU-2008283888-B2 (AU)
Title: Composite tack film for asphaltic paving, method of paving, and process for making a composite tack film for asphaltic paving
Inventor: SUGJOON LEE
IPC: E01C7/35
Filed: 2008-08-06
Granted: 2011-08-18
Abstract: A tack film material comprises a carrier substrate comprising a polymer film having first and second major surfaces. A surface layer on the first and second major surfaces comprises a resinous non-asphaltic material or a material including about 50% or more resinous non-asphaltic component and about 50% or less of asphaltic component. The surface layer is capable of forming a bond with an adjacent layer of asphaltic paving material, when the surface layer is heated to a temperature of about 120°C or more under a pressure that is applied to the tack film material by an overlying layer of the asphaltic paving material having a thickness of about 3.8 cm (1.5 inch) or more laid. The surface layer is not tacky at a temperature of about 20°C and a pressure of about one atmosphere.
Patent AU-2008289296-B2 (AU)
Title: Dual path blower method and apparatus
Inventor: PETERS CLIFFORD
IPC: A47L5/14
Filed: 2008-08-12
Granted: 2013-08-29
Abstract: An embodiment in accordance with the present invention provides a blower and a method for landscaping and lawn maintenance. The blower includes an outer housing having an inner chamber, the outer housing defining at least one discharge port and an impeller disposed within the inner chamber of the housing. The impeller has a first side surface and a second side surface, wherein a first plurality of blades are mounted to the first side surface and a second plurality of blades are mounted to the second side surface. The second plurality of blades are a mirror image of the first plurality of blades. Air or other fluid is expelled through the discharge ports and can be directed using discharge tubes in order to redistribute debris or fluid.
Patent AU-2008299220-B2 (AU)
Title: Compounds that modulate intracellular calcium
Inventor: STAUDERMAN KENNETH A
IPC: A61P3/14
Filed: 2008-08-15
Granted: 2011-07-21
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store -operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
Patent AU-2008303000-B2 (AU)
Title: Central bar for spraying and/or distributing products in powder, liquid and granulate formulations
Inventor: STAPELBROEK TRENNENPOHL ATILA
IPC: A01M7/00
Filed: 2008-08-29
Granted: 2013-03-07
Abstract: The central bar for spraying and/or distributing products in powder, liquid and granulate formulations refers to a central bar (1) to be fixed on the chassis (2a), between the front (2b) and the back (2c) wheels of a propeller vehicle (2), which is composed of a central frame set (3) and two side bars (4), where the central frame set (3) is composed of two brackets (3a) fixed to the chassis (2a) of said propeller vehicle (2); a horizontal pantograph subset (3b); two vertical pantograph subsets (3c), linked between them by the top side arms (3f) through an alternator axis (3i); two top articulation subsets (3e) formed from the extensions of the top side arms (3f); a shock absorption system, through bearings (3u) fixed to the inner walls of the brackets (3m) which are fixed to the side bars (4), wherein the internal braces (3n) are the end of the course; two bottom side subsets (3d) which are formed from the extensions of the bottom side arms (3h) driven by the hydraulic actuators (3t).
Patent AU-2008322072-B2 (AU)
Title: Disposable diaper
Inventor: SHIMADA TAKAAKI
IPC: A61F13/15
Filed: 2008-08-15
Granted: 2013-11-28
Abstract: A disposable diaper prevents side leakage of bodily wastes without a reduction in bodily fluid absorption performance and has excellent ability of retaining liquid and solid bodily wastes. Waist elastic members of front and rear waist regions (13, 14) each have a first waist elastic member (31) extending laterally near a waist opening (16), and also have a second waist elastic member (32) located between the first waist elastic member (31) and leg openings (17), extending laterally in opposite sides of each of the front and rear waist regions (13, 14), and not extending in the vicinity of the center of each of the front and rear waist regions (13, 14). The second waist elastic member (32) in the front waist region (13) extends laterally beyond side edge sections (44c) of the absorptive core (44) to the inward sides of the side edge sections (44c), and the second waist elastic member (32) in the rear waist region (14) extends from side edge sections (25) of the rear waist region (14) to the vicinity of the side edge sections (44c) of the absorptive core (44) without crossing the side edge sections (44c).
Patent AU-2008363323-B2 (AU)
Title: Sterile surgical tray
Inventor: HUMAYUN MARK
IPC: A61F9/007
Filed: 2008-10-22
Granted: 2014-10-09
Abstract: A sterile surgical tray (10) includes structure (12) for receiving a plurality of surgical instruments (14), a pump fluid reservoir (30) within the tray (10), a pump (40) contained within the sterile tray (30) and connected to the pump fluid reservoir (30), and a motor (42) contained within the sterile tray and connected to the pump (40). Sterile surgical tray (10) also may include electrical input and output connectors attached to tray (10).
Patent AU-2009202967-B2 (AU)
Title: A variable steering railway bogie
Inventor: SIMSON SCOTT
IPC: B61F5/38
Filed: 2009-07-23
Granted: 2013-07-11
Abstract: - 16 The present invention is directed to a variable steering railway bogie having a mounted vehicle body and including a frame, a plurality of wheelsets mounted to the frame wherein each of the wheelsets has an axle with two spaced apart wheels, 5 steering linkage means linking the wheelsets so that the wheelsets can cooperate to be in steering alignment, alignment means for positioning the body relative to the frame, variable steering means connecting the steering linkage means and the body, sensor means including sensors for monitoring the yaw angle and yaw velocity; and processor means for processing sensor means input and actuating the variable 10 steering means to control the steering of the wheelsets. 10 28 30 25 13 12 21 24 32 31 27 26
Patent AU-2009217359-B2 (AU)
Title: Compounds and compositions as modulators of GPR119 activity
Inventor: PIERRE-YVES MICHELLYS
IPC: A61K31/402
Filed: 2009-02-20
Granted: 2011-09-01
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of GPR119.
Patent AU-2009233398-B2 (AU)
Title: Package and applicator for liquid or semi-liquid composition
Inventor: CUNNINGHAM COREY THOMAS
IPC: B65D33/24
Filed: 2009-03-30
Granted: 2013-06-27
Abstract: The present disclosure provides a package for storing and applying a liquid or semi-liquid composition to an exposed surface. The package has a body having a first side, a second side, a first end, a second end, and an interior cavity located between the first and second ends wherein the first and second sides connect the first end to the second end, and an opening at the first end. A liquid or semi-liquid composition, meant to be applied to the surface, is located and stored in the interior cavity of the body. A substrate is included over the opening of the package capable of transferring the liquid or semi-liquid composition onto the surface. In an exemplary aspect, the package further includes a cover portion positioned over the opening which encloses the substrate and seals the opening in the package.
Patent AU-2009234101-B2 (AU)
Title: Method for generating anisotropic resistivity volumes from seismic and log data using a rock physics model
Inventor: ZHAN CARRIE XIN
IPC: G01V1/40
Filed: 2009-03-02
Granted: 2014-01-09
Abstract: A hydrocarbon exploration method is disclosed for generating anisotropic resistivity models of a subsurface reservoir from seismic and well data using a rock physics model. In one embodiment, the method comprises: selecting wells within a region of interest (101); obtaining a plurality of rock properties (102) and adjusting selected rock parameters (103) in the calibration of the rock physics model at the well locations; inverting porosity and shale content from seismic data (107); propagating the calibrated rock physics model to the region of interest (109) and calculating effective resistivity for the entire region of interest (109). The inventive method also provides for analyzing the uncertainty associated with the prediction of the resistivity volume.
Patent AU-2009244220-B2 (AU)
Title: Dual-polarization radar processing system using time domain method
Inventor: MOISSEEV DMITRI N
IPC: H03K7/04
Filed: 2009-05-07
Granted: 2013-09-12
Abstract: Embodiments of the present invention provide for improved estimation of environmental parameters in a dual-polarization radar system. In some embodiments, environmental parameters can be estimated using a linear combination of data received in two orthogonal polarization states. In particular, embodiments of the invention improve ground clutter and noise mitigation in dual polarization radar systems. Moreover, embodiments of the invention also provide for systems to determine the differential reflectivity and/or the magnitude of the co-polar correlation coefficient and the differential phase in a dual polarization radar system.
Patent AU-2009260757-B2 (AU)
Title: Data protection scheduling, such as providing a flexible backup window in a data protection system
Inventor: KOTTOMTHARAYIL RAJIV
IPC: G06F19/00
Filed: 2009-01-29
Granted: 2012-08-23
Abstract: A data protection scheduling system provides a flexible or rolling data protection window that analyzes various criteria to determine an optimal or near optimal time for performing data protection or secondary copy operations. While prior systems may have scheduled backups at an exact time (e.g., 2:00 a.m.), the system described herein dynamically determines when to perform the backups and other data protection storage operations, such as based on network load, CPU load, expected duration of the storage operation, rate of change of user activities, frequency of use of affected computer systems, trends, and so on.
Patent AU-2009275368-B2 (AU)
Title: Container
Inventor: ZAMUNER DORA
IPC: C11D17/04
Filed: 2009-07-20
Granted: 2013-02-21
Abstract: A container comprises a detergent formulation. The container includes a first enclosing wall. The first enclosing wall is permeable to water. The container includes a second enclosing wall. The second enclosing wall comprises a bleaching catalyst admixture and a support material.
Patent AU-2009275904-B2 (AU)
Title: Process for the synthesis of ezetimibe and intermediates useful therefor
Inventor: MRAVLJAK JANEZ
IPC: C07D263/26
Filed: 2009-07-29
Granted: 2014-08-14
Abstract: The present invention discloses novel and useful intermediates for the synthesis of ezetimibe (EZT), which intermediates share a characteristic Z-isomeric structure. Based on Z-5-(4-fluorophenyl)-pent-4-enoic acid, and proceeding the synthesis through further Z-intermediates, a total synthesis is presented to obtained final ezetimibe in high yields.
Patent AU-2009290965-B2 (AU)
Title: Medicament delivery device
Inventor: KARLSSON MARTIN
IPC: A61M5/20
Filed: 2009-09-07
Granted: 2012-05-17
Abstract: The present invention relates to a device for delivering medicament, comprising a generally elongated tubular housing having opposite distal and proximal ends, said tubular housing comprising a distal housing part and a proximal housing part releasebly connected to each other by first engagement means; a container inside said proximal housing part and arranged to contain medicament; a threaded plunger rod; a drive nut threadedly connected to the threaded plunger rod; a drive member having a tensioning wheel accessible outside the distal end of the distal housing part, said drive member being connected to the drive nut via a plunger housing arranged between said drive member and said drive nut; spring force means having a first end connected to the drive member and a second end connected to a fixed point on the distal housing part such that said spring force means is tensioned when said tensioning wheel and said drive member are rotated; a manually operated activation means releasable interconnected to said plunger housing by fourth engagement means for providing a rotational locking of the plunger housing in any direction when said drive member is rotated and said spring force means is tensioned, and for releasing said rotational locking when said fourth engagement are moved away from each other, such that said drive member, said plunger housing and said drive nut are rotated in the opposite direction forcing the plunger rod to move axially exerting pressure on the medicament inside the container for expelling a certain predetermined quantity of the medicament through a delivery member; wherein the device further comprises a guide nut arranged with guide ledges which cooperate with longitudinal grooves of the plunger for providing a rotational lock but allowing a longitudinal movement of the plunger rod in relation to the guide nut, and wherein said guide nut is rotationally locked to the distal housing part by fifth engagement means when the two housing parts are connected to each other; and pressure release means comprising slanting wedge-like surfaces arranged on said drive means and slanting wedge-like surfaces arranged on a fixed inner annular surface of the distal housing part, which slanting wedge-like surfaces are abutting each other such that they move out of contact near the end of the delivery of the predetermined quantity when the drive nut is rotated.
Patent AU-2009307894-B2 (AU)
Title: Replacement cartridge for a safety razor
Inventor: PENNELLA ANDREW
IPC: B26B21/40
Filed: 2009-10-13
Granted: 2015-07-02
Abstract: A replacement cartridge for a safety razor includes a dispensing head and a reservoir for a flowable shaving aid material. A removable shield is between the reservoir and the dispensing head and the shield interrupts fluid communication between channels of the reservoir and the dispensing head when the shield is in place. Fluid communication is permitted when the shield is removed. Removal of the shield is a onetime event. The shield can be a thermoplastic film. A razor cartridge can be disposed adjacent the dispensing head and the housing of the razor cartridge can be integrally formed with the housing of the dispensing head.