baber/WOPTO huggingface dataset:
Patent AU-2017320989-A1 (AU)
Title: Anti-gremlin-1 (GREM1) antibodies and methods of use thereof for treating pulmonary arterial hypertension
Inventor: CHALOTHORN DAN
IPC: C07K16/24
Filed: 2017-08-23
Abstract: The present invention provides anti-Gremlin-1 (GREM1) antibodies, and antigen-binding fragments thereof, as well as methods of use of such antibodies, or antigen-binding fragments thereof, for treating a subject having pulmonary arterial hypertension (PAH). It is disclosed a method of treating a subject having pulmonary arterial hypertension (PAH), comprising administering to the subject a therapeutically effective amount of an anti-gremlin-1 (GREM1) antibody, or antigen-binding fragment thereof, wherein the therapeutic effect of administration of the anti-GREMl antibody, or antigen-binding fragment thereof, to the subject is selected from the group consisting of inhibiting thickening of the pulmonary artery in the subject; increasing stroke volume in the subject; increasing right ventricle cardiac output in the subject; and extending survival time of the subject, thereby treating the subject having PAH.
Patent AU-2017351483-A1 (AU)
Title: Hard bouillon tablet
Inventor: PERDANA JIMMY
IPC: A23P10/28
Filed: 2017-10-20
Abstract: The invention relates to a hard bouillon tablet and to a process for the production of a hard bouillon tablet wherein a chicken fat having a total saturated fat content of 48 to 72 wt% (based on weight of total fat); and wherein the chicken fat comprises the fatty acids C16:0 in the range of 36 to 55 wt% (based on weight of total fat) and C18:0 in the range of 11 to 19 wt% (based on weight of total fat) is used.
Patent AU-2017371467-A1 (AU)
Title: Topical phenytoin for use in the treatment of peripheral neuropathic pain
Inventor: KOPSKY DAVID JOS
IPC: A61K31/00
Filed: 2017-12-06
Abstract: The present invention relates to pharmaceutical compositions containing phenytoin or phenytoin sodium for use in topical pain relief. Said use of the pharmaceutical composition of the invention reduces peripheral neuropathic pain. The topical pharmaceutical compositions of the invention containing phenytoin or phenytoin sodium, surprisingly reduce peripheral neuropathic pain considerably, especially and preferably in the conditions, characterized by a low to moderate grade of peripheral neurogenic inflammation, such as small fiber neuropathy, diabetic neuropathy, chronic idiopathic axonal polyneuropathy, post-herpetic neuralgia, trigeminus neuralgia, chemotherapy induced polyneuropathy, traumatic neuropathies, compression neuropathies, and infectious neuropathies in remission, according to the invention.
Patent AU-2017377661-A1 (AU)
Title: Reagents for treatment of oculopharyngeal muscular dystrophy (opmd) and use thereof
Inventor: STRINGS-UFOMBAH VANESSA
IPC: A61K48/00
Filed: 2017-12-14
Abstract: The present disclosure relates to RNA interference (RNAi) reagents, such as short hairpin microRNA (shmiR) and short hairpin RNA (shRNA), for treatment of oculopharyngeal muscular dystrophy (OPMD), compositions comprising same, and use thereof to treat individuals suffering from OPMD or which are predisposed thereto. The present disclosure also relates to the use of the RNAi reagents in combination with PABPN1 replacment reagents, such as constructs which encode functional PABPN1 protein, for treatment of OPMD, compositions comprising same, and use thereof to treat individuals suffering from OPMD or which are predisposed thereto.
Patent AU-2017380319-A1 (AU)
Title: Anti-counterfeit container
Inventor: FISCHBACH ELMAR MARTIN
IPC: B65D55/08
Filed: 2017-12-19
Abstract: The invention provides a container (1) for infant formula food with anti-counterfeit measures. In order to prevent counterfeiting, the container comprises a cover (30) for closing the container. An outer scannable code (12) is provided on the container so as to be scannable from the outside. Inside the container, a gas-tight membrane seal (20) for sealing a food content of the container prior to use is provided. On the gas-tight membrane seal, an inner scannable code (22) is provided so as to be only scannable after opening the container.
Patent AU-2017400606-A1 (AU)
Title: Systems and methods for providing a navigation route
Inventor: LIU BO
IPC: G08G1/00
Filed: 2017-09-27
Abstract: A system and method for providing navigation route are provided. The system and method may obtain a location of a service provider designated to receive a service order from a service requestor(710). The system and the method may generate one or more candidate navigation routes based on the service order and the location of the service provider(720). The system and the method may send the one or more candidate navigation routes to the service requestor(730). The system and method may obtain a candidate navigation route determined by the service requestor(740). The system and the method may send the determined candidate navigation route to the service provider(750).
Patent AU-2017436083-A1 (AU)
Title: Rapid response well control assembly
Inventor: CRAMM CARL
IPC: E21B33/064
Filed: 2017-10-17
Abstract: This disclosure provides a hybrid well capping stack system that uses a lower ram blow-out preventer (BOP) coupled to a gate valve-based capping stack that has first and second flowlines where the first flowline has a gate valve and the second flowline has a gate valve. At least one of the first and second flowlines is located on the frame to divert a flow of fluid laterally from a central flow axis of a wellbore.
Patent WO-2018157193-A1 (WO)
Title: Clapet anti-retour, système de collecte de données de fond de trou associé et ensemble cylindre central interne
Inventor: BEACH ANDREW PHILLIP
IPC: E21B10/02
Filed: 2018-01-17
Abstract: L'invention concerne un clapet anti-retour (18) qui peut être incorporé dans un ensemble cylindre central interne (10). Le clapet anti-retour (18) comprend un corps de clapet (20) qui définit un trajet d'écoulement de fluide (FP) et est pourvu d'un siège de clapet (24). Un élément de clapet (22) est situé dans le corps de clapet (20) et est accouplé au corps de clapet (20) par un mécanisme d'accouplement (37). Le mécanisme d'accouplement (37) est conçu pour permettre à l'élément de clapet (22) de se déplacer linéairement dans une direction axiale par rapport au corps de clapet (20) sur et hors du siège de clapet (24) et maintenir une relation de rotation fixe avec le corps de clapet (20). Un système d'acquisition de données (60) peut être maintenu dans l'élément de clapet (22) et grâce au mécanisme d'accouplement être maintenu en rotation fixe par rapport au corps de clapet un tube central interne (16) d'un ensemble cylindre central interne (10).
Patent WO-2018148796-A1 (WO)
Title: Appareil et système de génération d'électricité à échange de chaleur interfacé
Inventor: WEBB ROGER CLYDE
IPC: H01L31/0525
Filed: 2018-02-15
Abstract: L'invention concerne un appareil de génération d'électricité qui comprend un panneau solaire ayant une pluralité de cellules photovoltaïques, une pluralité de dalles de dissipateur thermique et un premier échangeur de chaleur dans un premier système de circulation à basse pression ayant une première pompe à basse pression pour la circulation d'un premier réfrigérant. La circulation à basse pression s'interface avec un échangeur de chaleur interfacé afin de transférer la chaleur à un deuxième réfrigérant dans un deuxième système de circulation ayant un troisième échangeur de chaleur disposé dans un réservoir de conservation d'eau. Une deuxième pompe fait circuler le deuxième réfrigérant. Une pluralité de vannes dans le premier échangeur de chaleur peuvent être ouvertes ou fermées pour permettre la variabilité du chemin d'écoulement.
Patent AU-2018203868-A1 (AU)
Title: Fusokines involving cytokines with strongly reduced receptor binding affinities
Inventor: TAVERNIER JAN
IPC: C07K14/575
Filed: 2018-06-01
Abstract: FUSOKINES INVOLVING CYTOKINES WITH STRONGLY REDUCED RECEPTOR BINDING Abstract The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases
Patent AU-2018230046-A1 (AU)
Title: Recombinant Herpes simplex virus and use thereof
Inventor: HUANG CHENGHAO
IPC: A61P35/00
Filed: 2018-02-28
Abstract: Provided is a recombinant Herpes simplex virus. The recombinant Herpes simplex virus does not express functional ICP0 protein and ICP34.5 protein; but expresses functional UL43 protein, functional UL41 protein (i.e. vhs protein), functional UL48 protein (i.e. VMW65 protein) or any combination thereof. Further provided are a virus vector constructed on the basis of the recombinant Herpes simplex virus, a pharmaceutical composition comprising the recombinant Herpes simplex virus or the virus vector, and use of the recombinant Herpes simplex virus or the virus vector.
Patent AU-2018235060-A1 (AU)
Title: Storage area for containers and method for operating a transport vehicle in a storage area of this type
Inventor: WIESCHEMANN ARMIN
IPC: B65G63/00
Filed: 2018-03-15
Abstract: The invention relates to a storage area (6) for containers (2), comprising at least one storage region (6a) and a gantry crane (8), wherein the storage region (6a) is arranged between two travel paths for the gantry crane, such that the gantry crane can be moved over the storage region on the travel paths, and wherein a transfer region (10, 11) is arranged between the travel paths at an end of the storage region (6a) pointing in the travel direction of the gantry crane, which can be reached by the gantry crane (8) and by a transport vehicle (7, 13) for containers (2), in order to transfer containers (2) into the storage area (6) and out of the storage area (6). In order to improve a storage area (6) of this type, according to the invention, an intermediate region (29) is provided between the transfer region and the storage region; the transfer region and the intermediate region (29) are designed and arranged in such a way that a passage through the transfer region and travel in the intermediate region (29) is possible for a transport vehicle (7, 13), and the travel in the intermediate region is possible before or after the passage through the transfer region.
Patent AU-2018242607-A1 (AU)
Title: A rapid, on-demand heparin-induced thrombocytopenia functional assay
Inventor: ALKHALFIOUI FATIMA
IPC: G01N33/68
Filed: 2018-03-29
Abstract: A method for assaying a heparin-induced thrombocytopenia (HIT) in a patient's serum or plasma sample, the method comprising: incubating a mix of platelets with the patient's serum or plasma sample in the presence of either a low concentration of heparin or a high concentration of heparin; incubating a mix of platelets in the presence or absence of a platelet activator; quantifying platelets and activated platelets in the mixes; calculating percentage of activated platelets within the platelets for each of the mixes; calculating a heparin platelet activation (HEPLA) index using the calculated percentages; measuring and calculating HEPLA indices of serum or plasma samples from donors not suffering from HIT; calculating cut-off values from the HEPLA indices of serum or plasma samples from donors not suffering from HIT, and determining whether a patient suffers of HIT or not by comparing the HEPLA index of the patient with the cut-off values.
Patent AU-2018248130-A1 (AU)
Title: Rule deviation configuration for offender monitoring devices
Inventor: SEGAL DAVID SOLOMON
IPC: G08B25/00
Filed: 2018-03-29
Abstract: According to aspects of this disclosure, a monitored person, via an end-user computing device, may generate a rule deviation request and send the rule deviation request to the computing system of the supervising agency. Based on the received request, the computing system may, upon receiving an indication that the request is authorized, determine a reconfigured rule and enforce the reconfigured rule. In some instances, the computing system may be configured to suppress an alert that would have been generated based on an activity prohibited by initial rule but that is permitted by the reconfigured rule. The reconfigured rule may remain in effect for a duration specified by the request. In this way, the techniques may increase the efficiency with which rule deviation requests are processed and enforced.
Patent AU-2018250355-A1 (AU)
Title: Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides
Inventor: LANTHIER CHRISTOPHER M
IPC: C07D213/62
Filed: 2018-10-15
Abstract: Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino] alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5- heteroaryl substituted [(3 -hydroxypyridine-2-carbonyl] amino } acetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl] amino } acetic acid esters and {[3 hydroxypyridine-2-carbonyl] amino } acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.
Patent AU-2018269550-A1 (AU)
Title: Components with high API loading
Inventor: TRAVERSO CARLO GIOVANNI
IPC: A61M37/00
Filed: 2018-05-17
Abstract: Components with relatively high loading of active pharmaceutical ingredients are generally provided. In some embodiments, the component (e.g., a tissue interfacing component) comprises a solid therapeutic agent and a supporting material such that the solid therapeutic agent is present in the component in an amount of greater than or equal to 10 wt% versus the total weight of the tissue interfacing component. Such tissue-interfacing components may be useful for delivery of API doses e.g., to a subject. Advantageously, in some embodiments, the reduction of volume required to deliver the required API dose as compared to a liquid formulation permits the creation of solid needle delivery systems for a wide variety of drugs in a variety of places/tissues (e.g., tongue, Gl mucosal tissue, skin) and/or reduces and/or eliminates the application of an external force in order to inject a drug solution through the small opening in the needle. In some cases, a physiologically relevant dose may be present in a single tissue interfacing component.
Patent AU-2018270925-A1 (AU)
Title: Recombinant human acid alpha-glucosidase
Inventor: DO HUNG
IPC: A61P43/00
Filed: 2018-05-15
Abstract: Provided are a recombinant acid α-glucosidase and pharmaceutical composition comprising a recombinant acid α-glucosidase, wherein the recombinant acid α-glucosidase is expressed in Chinese hamster ovary (CHO) cells and comprises an increased content of N-glycan units bearing one or two mannose-6-phosphate residues when compared to a content of N-glycan units bearing one or two mannose-6-phosphate residues of alglucosidase alfa. Also provided herein are methods of producing, purifying, and formulating the recombinant acid α-glucosidase or pharmaceutical composition for administration to a subject and methods of treating a disease or disorder such as Pompe disease using the recombinant acid α-glucosidase or pharmaceutical composition.
Patent AU-2018282481-A1 (AU)
Title: An online system for employment of temporary employees
Inventor: LEONIDAS PATRICK
IPC: G06Q10/06
Filed: 2018-12-21
Abstract: AN ONLINE SYSTEM FOR EMPLOYMENT OF TEMPORARY EMPLOYEES Abstract The present invention relates to an online system for employment of temporary employees. In particular, the invention relates to an online system for employment of temporary employees where the system comprises a location device for sensing or pre-assessing the location relations between the prospective employer and the prospective temporary employee. The system automatically matches prospective employers with prospective temporary employees that have been pre-assessed and allows direct offer and acceptance between the two parties. In addition, there is selective pressure exerted on each of the two parties in the form of timed communication wherein an automatic countdown timer controls communications between prospective employers and prospective temporary employees by creating predefined time periods to accept or reject employment.
Patent AU-2018297551-A1 (AU)
Title: A polyethylene pipe
Inventor: WEYLAND TANIA
IPC: F16L9/12
Filed: 2018-07-03
Abstract: A polyethylene pipe comprising components A) and B), wherein component A) is a hindered amine light stabilizer containing a triazine residue, component B) is a natural or synthetic hydrotalcite and the weight ratio of component A) to component B) is 1:10 to 10:1.
Patent AU-2018302405-A1 (AU)
Title: Method for prediction of response to cardiovascular regeneration
Inventor: STEINHOFF GUSTAV
IPC: G01N33/68
Filed: 2018-07-16
Abstract: The present invention relates to a method for prediction of response to cardiovascular regeneration comprising the use of biomarkers. Further, the present invention relates to a combination of the biomarkers for use in a method for prediction of response to cardiovascular regeneration, a computer device to perform a method according to the present invention and a device adapted for carrying out the inventive method.
Patent AU-2018311197-A1 (AU)
Title: Self-propelled machine
Inventor: KALVERKAMP FELIX
IPC: A01B51/02
Filed: 2018-07-31
Abstract: The invention relates to a self-propelled machine for agriculture, having a support structure (T) which receives various attachment devices (2), has at least one drive assembly (3) having a control module (4), is movable by means of ground supports (B, B') on the end, and forms an agricultural gantry system, having at least one base carrier (6), for variable work tasks, which gantry system, proceeding from a road orientation defining a travel width (dimension FB), can be converted to a working orientation having a substantially larger working width (AB), wherein the support structure (T) has lateral carriers (ST, ST') comprising the ground supports (B, B'). The support structure defining a longitudinal orientation in the road orientation has, in the region of its two ground supports (B, B') on the end thereof, a vertical longitudinal center plane (M) extending therebetween. In spatial orientation thereto, a functional frame (FR, FR') having an asymmetrical base carrier (6') is proposed as a support structure. According to the invention, the base carrier (6), proceeding from the longitudinal dimension (FB) of the possible travel width(s), is connected to the at least one lateral carrier (ST, ST') in an outer third (TD, TD') of said longitudinal dimension (FB).
Patent AU-2018312823-A1 (AU)
Title: Boysenberry, apple, and blackcurrant compositions and methods of preparation and use therefor
Inventor: SHAW ODETTE M
IPC: A61P11/00
Filed: 2018-08-08
Abstract: The present disclosure encompasses compositions prepared from Boysenberry and apple, as well as compositions prepared from Boysenberry, apple and blackcurrant. Also encompassed are methods of preparing these compositions and methods of using these compositions, in particular, for treating or preventing disorders of the respiratory system, including amongst others: inflammation, asthma, chronic obstructive pulmonary disease, allergic airways inflammation, reactive airway disease, airway fibrosis, and airway remodelling.
Patent AU-2018337912-A1 (AU)
Title: Geogrids
Inventor: CURSON ANDREW
IPC: B29D28/00
Filed: 2018-09-19
Abstract: There is disclosed a geogrid in the form of an integral, mesh structure comprising molecularly orientated polymeric material, the mesh structure formed of interconnecting mesh defining elements including elongate tensile elements wherein the molecular orientation of the mesh structure is uniform throughout the extent thereof. A method of making the geogrid is also described and its use in stabilizing, reinforcing or strengthening a mass of particulate material.
Patent AU-2018344825-A1 (AU)
Title: A valve for controlling fluid flow, a fluid distribution system and a method for measuring differential pressure
Inventor: JILDEROS DANIEL
IPC: G01L13/00
Filed: 2018-10-01
Abstract: The present inventive concept relates to a valve for controlling fluid flow. The valve comprises a valve body, a chamber arranged inside of the valve body, a fluid inlet for providing fluid to the chamber, and a fluid outlet for receiving fluid from the chamber. The valve further comprises a closing arrangement for controlling the flow of fluid from the fluid inlet to the fluid outlet via the chamber, and a differential pressure sensor for measuring the differential pressure over the closing arrangement, between an upstream pressure and a downstream pressure. The differential pressure sensor is integrated in the valve body, and is arranged to measure the differential pressure for at least an open state of the closing arrangement.
Patent AU-2018352102-A1 (AU)
Title: Methods and apparatus for constructing airships
Inventor: BRIN SERGEY
IPC: B64B1/08
Filed: 2018-10-11
Abstract: Systems, apparatuses, and methods for constructing an airship quickly and cost-effectively are described. In one embodiments, an airship structure may have a plurality of mainframes, each comprising interconnected pyramid structures. One of the pyramid structures may include an apex joint, four base joints, first connectors, and second connectors. The apex joint and base joints may each have slots configured for receiving connectors. The apex joint may have four apex -to-base slots and each base joint may have a base-to-apex slot and two base-to-base slots. Each of the first connectors may connect the apex joint to one of the four base joints using one of the apex-to-base slots of the apex joint and the base-to-apex slot of that base joint. Each of the second connectors may connect two of the four base joints using one of the base-to-base slots of each of the two base joints connected by that second connector.
Patent AU-2018390164-A1 (AU)
Title: Non-impulsive source actuation
Inventor: ORJI OKWUDILI
IPC: G01V1/38
Filed: 2018-12-18
Abstract: Non-impulsive source actuation can include actuating a plurality of non-impulsive sources such that each one of a plurality of common midpoint (CMP) bins receives a desired aggregate signal exposure. Each one of the plurality of non-impulsive sources exposes each one of the plurality of CMP bins to a different part of the desired aggregate signal exposure at different times during the survey.
Patent AU-2018401068-A1 (AU)
Title: Wireless power supply system applied to refrigerating device, drawer assembly, and refrigerating device
Inventor: HUI BIN
IPC: H02J7/00
Filed: 2018-12-24
Abstract: Provided are a wireless power supply system (100) applied to a refrigerating device, a drawer assembly (200) and the refrigerating device. The wireless power supply system (100) comprises a control module (1), a display control module (2), a wireless communication module (3), a wireless power supply module (4), a battery module (5), and a detection module (6). The wireless power supply module (4) comprises a wireless power supply receiving module (41) and a wireless power supply transmitting module (42); when the wireless power supply receiving module (41) gets close to the wireless power supply transmitting module (42) so as to achieve electrical connection, the display control module (2) is switched on; when the detection module (6) detects that the wireless power supply receiving module (41) gets away from the wireless power supply transmitting module (42) so as to achieve disconnection, the battery module (5) is discharged to switch on the display control module (2) so as to continuously supply power to the display control module (2).