baber/WOPTO huggingface dataset:
Patent CA-2284611-A1 (CA)
Title: Replication-competent herpes simplex viruses
Inventor: PYLES RICHARD B
IPC: A61K48/00
Filed: 1998-03-27
Abstract: A promising approach for the therapeutic treatment of brain tumors utilizes replication-competent, neuroattenuated herpes simplex virus-1 (HSV-1) mutants.  This approach requires mutation of HSV-1 to eliminate killing of normal, non-dividing cells of the brain (e.g., neurons). The present invention discloses methods for killing malignant brain tumor cells in vivo entails providing replication competent herpes simplex virus vectors to tumor cells. A  replication competent herpes simplex virus vector, with defective expression of the gamma 34.5 gene and the uracil DNA glycosylase (UNG) gene, specifically destroys tumor cells, is hypersensitive to anti-viral agents, and is not neurovirulent.
Patent CA-2285523-A1 (CA)
Title: Group 8, 9 or 10 olefin copolymerization catalyst
Inventor: WANG QINYAN
IPC: C07F9/58
Filed: 1999-10-01
Abstract: Olefin co- or homopolymers having a good molecular weight and short chain branching may be prepared in the presence of a pyridyl bridged bisphosphinimine complex of a Group 8, 9 or 10 metal.
Patent CA-2286079-A1 (CA)
Inventor: REMON JEAN PAUL LOUIS AUGUSTE
IPC: A61P31/04
Filed: 1998-03-19
Abstract: L'invention concerne des comprimés obtenus par compression directe et non enrobés contenant du monohydrate de céfadroxil en tant que principe actif, pouvant être administrés par voie orale à l'homme. Ils peuvent être avalés, mastiqués ou désintégrés dans l'eau, ce qui donne une dispersion buvable.
Patent CA-2288829-A1 (CA)
Inventor: HORNBY DAVID M
IPC: B24D7/04
Filed: 1998-05-08
Abstract: Cleaning and polishing automotive panels with a combination pad (8). A support (18) holds a circular replaceable, disposable cleaning/polishing pad (14) on a rotatable power tool. The pad is made of compressible/expandable foam. The pad (14) has front and rear recesses that define concentric radially outer and inner sections. The outer section normally protrudes forwardly of the cleaning surface so that when it is first brought into engagement with a work surface, the cleaning surface (26) does not engage the work. A pressure-applying backup plate (11) initially compresses the outer pad section and positions the cleaning surface at the work surface. Further force acts to allow the pad outer section to expand and move the cleaning element out of engagement with the work surface, allowing the rotating foam outer section to be used to polish the cleaned area of the work.
Patent CA-2290861-A1 (CA)
Title: A method and apparatus for packing wire in a storage drum
Inventor: COOPER WILLIAM D
IPC: B23K9/133
Filed: 1999-11-25
Abstract: A method and apparatus for densely packing wire in a storage drum is provided.  A capstan is provided for pulling welding wire at a set rotational velocity. The welding wire is then provided to a rotatable laying head which receives the wire from the capstan, and in turn rotates with a storage drum placed on a rotatable turntable. As the welding wire is placed within the turntable in layers, the turntable is indexed relative to the storage drum axis and the rotational velocity of the capstan and laying head is altered, which causes the welding wire to be placed in a layer different from the first layer. This indexing is continued until the storage drum is full, forming alternating bands of welding wire to increase the packing density of the storage drum.
Patent CA-2291012-A1 (CA)
Title: Robot control method and device
Inventor: TOMISAKI HIDENORI
IPC: G05B19/19
Filed: 1998-05-26
Abstract: When a multiaxial robot with a mechanism having spring elements between electric motors of respective axes and robot arms is controlled, the path precision of a tool tip is increased without causing vibrations produced by mechanical interference between axes and high-frequency vibrations of electric motors. A model controller (1) is supplied with position commands X ref_L, X ref_U with respect to the electric motors and outputs model motor position commands .theta.Mm_L, .theta.Mm_U, model motor speed commands ~.Mm_L, ~Mm_U, and model feed-forward commands U FF_L, U FF_U to feedback controllers (10L, 10U) which actuate and control the electric motors and the robot arms. The model controller (1) includes therein corrective quantity calculators (3L, 3U) for calculating corrective quantities (corrective torques) in view of interfering forces acting between the axes from the other axes to cancel the interfering forces. The model controller (1) outputs the model feed-forward commands with the corrective quantities added thereto.
Patent CA-2294138-A1 (CA)
Title: Cd154 blockade therapy for therapeutic protein inhibitor syndrome
Inventor: ADELMAN BURT
IPC: A61P43/00
Filed: 1998-06-19
Abstract: Methods and compositions for attenuating or mitigating; suppressing;  preventing; delaying onset of; or, reversing exogenous protein inhibitor syndromes, exemplified by clotting factor (e.g., Factor VIII) inhibitor syndromes. The described methods use a CD40:CD154 binding interruptor, such as CD154 blocking agent, to attenuate or ameliorate counter-adaptive, bioinhibitory humoral immunity directed against an exogenous protein of therapeutic value.
Patent CA-2295057-A1 (CA)
Title: Adjustable machine for the vertical orientation and alignment of empty containers
Inventor: MARTI SALA JAIME
IPC: B65G47/84
Filed: 1998-05-21
Abstract: An adjustable unit for the unscrambling and lined up delivery of empty containers, said unit comprising a plurality of compartments (6) connected to a first rotary structure (7) to receive containers (A) in a lying position, said compartments (6) having an open bottom delimited by arrangements (11 and 12) for supporting the open end (A1) of the container (A) in the vicinity of the leading and trailing sides, a plurality of discharge chutes (8) associated to said structure (7) below each compartment (6) to receive the containers (A) as they fall, and to thus transfer them in an upright position and in a lined up arrangement onto another equipment, and a supporting stationary floor (9) interposed between said compartments (6) and said chutes (8), with a discharge gap (10), said arrangement for supporting the open end (A1) of the container (A) in the vicinity of said leading side of the compartment (6) comprising an elongated member (11) apt to be shifted within the compartment in order to thus adapt its position to the size of the container, all of the members (11) being associated to a second structure (14) that travels along with said first structure (7), the relative position of the second structure (14) with respect to the first structure (7) being adjustable.
Patent CA-2298521-A1 (CA)
Title: Method for fastening a flat strip lamella to the surface of a building component
Inventor: STEINER WERNER
IPC: E04G23/02
Filed: 1998-07-15
Abstract: The invention relates to a method for fastening a flat strip lamella to the surface of a building component. According to the inventive method, the face of the flat strip lamella is pressed against the surface of the building using an adhesive coating consisting of a reaction resin applied in a paste-like consistency and hardened to form an adhesive joint. The flat strip lamella comprises a plurality of carbon fibers which are embedded in a binder matrix and placed parallel to each other in a longitudinal direction. In order to increase the speed at which the adhesive coating hardens, the invention provides that an electrical current flows through at least one part of the carbon fibers, heating the flat strip lamella which in turn heats the adhesive coating.
Patent CA-2301217-A1 (CA)
Title: Method and apparatus for establishing a through path for a communication signal
Inventor: MORAN TIMOTHY LEO
IPC: H04Q11/04
Filed: 1998-05-22
Abstract: A method for establishing a path for a communication signal is performed in a wireless communication system which includes a plurality of interconnected wireless network elements (510, 514, 515, 516), and a landline communications network which includes a plurality of interconnected landline network elements (305, 404, 508). The method includes establishing a first signaling link (501, 330) between a communication unit (206) and a landline network element (404), followed by establishing, by the landline network element (404), a second signaling link (522, 524) between the landline network element (404) and a wireless network element (514). The communication unit (206) transmits mobility-related messaging associated with the communication signal to the wireless network element (514) via the first and second signaling links.
Patent CA-2301267-A1 (CA)
Inventor: HWANG KIN-KAI
IPC: A61K47/42
Filed: 1998-07-21
Abstract: The present invention relates to a method of enhancing the bioavailability of a piperidinoalkanol antihistamine in a patient which comprises co-administering to said patient an effective antihistaminic amount of said piperidinoalkanol and an effective p-glycoprotein inhibiting amount of a p-glycoprotein inhibitor.
Patent CA-2301693-A1 (CA)
Inventor: PAULISTA MICHAEL
IPC: A61K38/00
Filed: 1998-09-21
Abstract: Composition pharmaceutique ayant une activité neurotrophique, qui comporte une quantité biologiquement active d'au moins deux cytokines, l'une des deux cytokines étant BMP, GDF, TGF-.beta. ou GDNF.
Patent CA-2302519-A1 (CA)
Title: Systeme de boite postale personnelle a ligne telephonique
Inventor: PARK HYUNG SIK
IPC: H04M1/652
Filed: 1999-06-30
Abstract: L'invention concerne un système de boîte postale utilisant une ligne téléphonique, comprenant une boîte postale connectée à une prise téléphonique pour la réception d'un appel téléphonique déterminé, avec commande de commutation d'une charge suivant un signal d'entrée via la prise téléphonique, mémorisation d'un numéro de téléphone déterminé d'un demandeur, enregistrement d'un message oral déterminé par le demandeur et information d'une réception du message à un abonné, ainsi qu'une unité de commutation pour la commutation d'une puissance d'entrée alimentant une pluralité de charges, en conformité avec une commande de la boîte postale, en vue de télécommander un fonctionnement marche/arrêt d'un interrupteur, par rapport à une certaine charge, via une ligne téléphonique, répondre automatiquement à un appel émanant d'un demandeur déterminé, informer automatiquement un abonné en lui transmettant un message enregistré et effectuer un service boîte postale vocale qui est généralement réalisé par un fournisseur de service téléphonique.
Patent CA-2303093-A1 (CA)
Title: Appareil d'impression a sec portable et manuel
Inventor: BUSSIERE ERIC
IPC: B41F19/06
Filed: 1999-08-20
Abstract: L'invention concerne un appareil (10, 500) d'impression à sec portable et manuel comprenant un cadre (11, 501, 502), une poignée (12, 13) reliée au cadre, une unité (215, 535) d'impression à sec montée sur la partie inférieure du cadre, un passage de convection d'air et un élément (16, 503). L'unité d'impression à sec est équipée, à son tour, d'une matrice et d'une source thermique permettant de chauffer la matrice. Le passage de convection d'air se trouve entre la poignée et l'ensemble matrice/source thermique. Un porte-ruban (14) peut être monté sur la partie supérieure du cadre pour alimenter un ruban (156) d'impression à sec et un système de guidage du ruban guide ce ruban le long d'un trajet s'étendant entre la matrice et une surface à imprimer à sec. L'élément guide guide la matrice vers la surface à imprimer à sec. Ce guide, monté télescopiquement sur le cadre, peut être déployé ou rétracté et est sollicité (230, 236) par un ressort vers la position déployée.
Patent CA-2305915-A1 (CA)
Title: Transaction tray with communications means
Inventor: MAXYMYCH PETER NICHOLAS
IPC: G06K11/06
Filed: 2000-04-13
Abstract: A transaction tray comprises a surface having a first writing portion, a display screen and communications means for receiving information to be displayed on the display screen, wherein the information which is received by the communications means is received from a source remote from said apparatus. The communications means may be a wireless communications means, a two-way communications means or a hard wired communications means. Further, a transaction tray comprises a tray portion and a hinged lid portion, lighting means associated with the tray portion, a first transparent window is provided in the outer surface of the lid and a second transparent window in the inner surface. A  first translucent advertising substrate is displayed in the first window and a second translucent advertising substrate is displayed in the second window. Communications means is provided to receive information to be displayed on the first and second translucent advertising substrates, wherein said information is received by said communications means from a source remote from said transaction tray.
Patent CA-2307972-A1 (CA)
Title: Low pressure, high temperature composite bridge plug
Inventor: HAWKINS THOMAS W
IPC: E21B33/129
Filed: 2000-05-10
Abstract: A low pressure, high temperature composite bridge plug.      The bridge plug comprises a mandrel with a plurality of slips disposed therearound. A wedge is initially attached to said mandrel and in planar contact with the slips for forcing the slips radially outwardly into gripping engagement with a wellbore. An elastomeric sealing element is disposed on the mandrel and compressed between the wedge and a shoulder on the mandrel to expand the packing element radially outward into sealing engagement with the wellbore. A plurality of ratchets retained in a ratchet body grippingly engage the mandrel to prevent the plug from unsetting. The mandrel, slips, wedge and ratchet body are preferably made of non-metallic, composite materials for easy drilling.
Patent CA-2308004-A1 (CA)
Title: Multiple displacement amplification
Inventor: LIZARDI PAUL M
IPC: C12Q1/68
Filed: 1998-10-08
Abstract: Disclosed are compositions and a method for amplification of nucleic acid sequences of interest. The method is based on stand displacement replication of the nucleic acid sequences of interest by multiple primers. In one preferred form of the method, referred to as multiple strand displacement amplification, two sets of primers are used, a right set and a left set. The primers in the right set are complementary to one strand of the nucleic acid molecule to be amplified and the primers in the left set are complementary to the opposite strand. The 5' end of primers in both sets are distal to the nucleic acid sequence of interest when the primers have hybridized to the nucleic acid sequence molecule to be amplified. Amplification proceeds by replication initiated at each primer and continuing through the nucleic acid sequence of interest. A key feature of this method is the displacement of intervening primers during replication by the polymerase. In another preferred form of the method, referred to as whole genome strand displacement amplification, a random set of primers is used to randomly prime a sample of genomic nucleic acid (or another sample of nucleic acid of high complexity).  By choosing a set of primers which are sufficiently random, the primers in the set will be collectively, and randomly, complementary to nucleic acid sequences distributed throughout nucleic acid in the sample. Amplification proceeds by replication with a highly processive polymerase initiated at each primer and continuing until spontaneous termination. A key feature of this method is the displacement of intervening primers during replication by the polymerase. In this way, multiple overlapping copies of the entire genome to be synthesized in a short time.
Patent CA-2309686-A1 (CA)
Title: Composition useful for providing one-step surgical preparation and drape
Inventor: RAWLS H RALPH
IPC: A61P31/04
Filed: 1998-12-10
Abstract: This invention relates to an improved polyvinylidene fluoride-based composition useful for forming a flexible, tack-free, nonflammable, substantially fluid resistant barrier film with substantially improved durability and skin-adhesion properties. The composition providing a longlasting protective barrier film capable of disinfecting the skin surface of normally present microorganisms upon initial application, and the film imparting continuous and prolonged antimicrobial agent. The barrier film is further capable of remaining substantially adherent to the skin surface after prolonged exposure to biological fluids. A kit and methods of use for the composition are disclosed. The figure illustrates the moisture vapor transmission rate (MTVR) for the present invention. The MTVR of the present invention containing both chlorhexidine acetate (CHA) and silver sulfadiazine (AgSD), chlorhexidine alone, and with no antimicrobial agent present is compared against BLISTERFILM~TM hydrocolloid wound dressing and Saran(R) food wrap. The percent of water loss is plotted versus time in days. The data illustrating the present invention is breathable, thereby providing patient comfort and promotion of wound healing. See Test #3 for details.
Patent CA-2310469-A1 (CA)
Title: Joint for fluid conveyance piping
Inventor: DEL BUE PAOLO
IPC: F16L33/207
Filed: 2000-06-01
Abstract: The joint for fluid conveyance piping is constituted by the interpenetrating coaxial insertion of two facing ends of pipe segments with interposed ratchet means for retention and perimetric means for clamping the interpenetrating ends.
Patent CA-2311977-A1 (CA)
Title: Method for delivering a fluid into a vessel of a human body, and improved cannula useful for carrying out the method
Inventor: KERKHOFFS WOLFGANG
IPC: A61M31/00
Filed: 2000-06-19
Abstract: A method for delivering a fluid into a vessel, in particular into an aortic arch, includes the step of imposing on each fluid particle an axial motion as well as a whirling motion when entering the vessel. Hereby, a novel and inventive cannula which includes a tubular body; and a device for imposing a whirling motion on each fluid particle of a fluid entering through the tubular body into a vessel.
Patent CA-2313117-A1 (CA)
Inventor: MONRAD ATLE
IPC: H04W60/02
Filed: 1998-12-08
Abstract: The present invention relates to a method for routing area (RA) update request messages which in accordance with a time period broadcasted from the network are periodically sent from an MS (Mobile Station) to an SGSN (Serving GPRS Support Node) through a BSS (Base Station System), which SGSN supports GPRS (General Packet Radio Service), and which as a result of a routing area update procedure will return an appropriate accept message, and for the purpose of taking into account the differentiation in nature of normal routing area update procedure and periodic updates, it is according to the present invention suggested that for the purpose of simplifying said routing area update procedure, there is broadcasted a new indicator from the network together with the time period for the periodic routing updates, said indicator being adapted to determine whether the periodic routing update procedure is performed ciphered instead of unciphered.
Patent CA-2315511-A1 (CA)
Title: Carpet backing that provides dimensional stability
Inventor: IRWIN DONALD A SR
IPC: D05C17/02
Filed: 2000-08-08
Abstract: A tufted carpet is made by tufting yarn through a primary backing of at least two layers, including a first backing layer 14 and a second backing layer 15. The first backing layer 14 is formed of a woven material, a non-woven material, a plastic sheet material, a plastic extrusion, or a composite of a woven or non-woven material and a plastic sheet material. The second backing layer 15 is formed of a woven material of ribbons of polypropylene, polyethylene or combinations of polypropylene and polyethylene, a woven fiber glass material, a leno weave material, an open weave material, a plastic net or a plastic sheet material. A plurality of tufts 21 of yarn that are sewn through the primary backing are exposed on one side of the primary backing for forming face yarns, and also form a plurality of back stitches 22 on the opposite side of the primary backing. At least a major portion of the back stitches secure each layer of the primary backing to each other layer.
Patent CA-2317601-A1 (CA)
Title: Combined percussion and trepan laser drilling
Inventor: VANASSE STEVE
IPC: B23K26/08
Filed: 1998-11-03
Abstract: A process is provided for laser drilling relatively large and deep holes in superalloy components by percussion laser drilling a central hole through the component to a diameter less than the predetermined diameter, then trepanning laser drilling around the central hole to expand the diameter of the hole to the predetermined diameter.
Patent CA-2320221-A1 (CA)
Inventor: VADEKAR ASHOK V
IPC: G09C1/00
Filed: 1999-02-01
Abstract: A protocol for authenticating at least one of a pair of first and second correspondents C and T in a data communication system, the method comprising the steps of storing a public key in the first correspondent C; computing a shared secret by the second correspondent T incorporating the public key C; storing the shared secret in the first correspondent C; the second correspondent T generating a challenge value ; the first correspondent C transmitting to the second correspondent T information including the stored public key C; the second correspondent T computing a test shared secret from the received public key C; the first and second correspondents computing response signals using the challenge value and the shared secret in a one-way function f1; and the first correspondent C transmitting the computed response signal to the second correspondent T whereby the second correspondent verifies the first correspondent.
Patent CA-2324568-A1 (CA)
Title: Sustained-release preparation of physiologically active polypeptide and production thereof
Inventor: IWASA SUSUMU
IPC: A61K38/27
Filed: 1999-03-18
Abstract: A method for producing a sustained-release preparation, which comprises dispersing a physiologically active polypeptide into an organic solvent solution of a biodegradable polymer and removing the organic solvent, wherein the polypeptide is a powder obtained by lyophilizing an aqueous solution of the polypeptide which solution has a water-miscible organic solvent and/or a volatile salt; which is improved the easiness of handling of the physiologically active polypeptide powder in the process for producing the preparation; which is possible to industrially produce the sustained-release preparation in large scale; which provides a sustained-release preparation showing high and stable concentration of the active component in blood in long term, low initial release ratio of the physiologically active polypeptide, and high entrapment ratio of the polypeptide into the sustained-release preparation.