baber/WOPTO huggingface dataset:
Patent NZ-532909-A (NZ)
Title: Peroxisome proliferator activated receptor agonists
Inventor: GIBSON TRACEY ANN
IPC: A61P3/04
Filed: 2002-11-26
Abstract: Disclosed herein are compounds of formula (I), wherein (a) R1 is selected from the group consisting of hydrogen, substituted or unsubstituted group selected from C1-C8 alkyl, aryl-C0-4-alkyl, heteroaryl-C0-4-alkyl, C3-C6 cycloalkylaryl-C0-2-alkyl, and -CH2-C(O)-R17-R18, wherein R17 is O or NH and R18 is optionally substituted benzyl; (b) R2 is selected from the group consisting of C1-C6 alkyl, C1-C6 alkenyl, aryl-C0-4-alkyl, heteroaryl-C0-4-alkyl, C1-C4 alkyl sulfonamide, C1-C4 alkyl amide, OR10 and C3-C6 cycloalkyl; (c) W is O or S; (d) X is an optionally substituted C1-C5 alkylene linker wherein one carbon atom of the linker may optionally be replaced with O, NH, S, and optionally two carbons together may form a double bond; (e) Y is selected from the group consisting of C, O, S, NH and a single bond; and (f) E is selected from the group consisting of C(R3) (R4 )A, A, and a substituted or unsubstituted group selected from the group consisting of (CH2)n COOR19, and wherein the other variables shown herein are as defined in the specification. These compounds are suitable for the manufacture of a medicament for the treatment of a condition modulated by a peroxisome proliferator activated receptor (PPAR).
Patent NZ-536406-A (NZ)
Title: Optometry measurement device for measuring characteristics of a human eye
Inventor: AVUDAINAYAGAM CHITRALEKHA S
IPC: G02B5/32
Filed: 2003-04-24
Abstract: A device for measuring spherical refractive error of the human eye of a subject comprises: an holographic element (14) recording an image wavefront (15) of a three dimensional array (1) of indicia; and means for illuminating the holographic element with a plane wavefront of visible light such that when viewed the patient sees a reconstructed image of the array of indicia; wherein each indicia is seen at a different perceived distance from the subject, wherein the array of indicia comprises radial line pattern.
Patent NZ-536567-A (NZ)
Title: Riding Saddle comprising a saddle tree, a cantle end, a pommel end, a saddle flap unit and a panel unit
Inventor: KEMPSELL DAVID
IPC: B68C1/02
Filed: 2003-04-16
Abstract: The present invention relates to a modular saddle. There is provided a saddle having a saddle tree unit, a saddle flap unit and a panel unit, wherein the panel unit and saddle flap unit are removably securable to the saddle tree unit. The flap unit comprises two flap components each having a sweat flap and saddle flap. Each flap component is removable from the saddle tree in one piece. The panel unit includes plates, which extend the bearing surface of the saddle tree, and prevent the formation of pressure points. In another aspect of the present invention there is provided a flexible tree made from a polyurethane resin. The tree further includes a Y-shaped carbon fibre strengthening bar, which enables the tree to flex laterally, but not longitudinally.
Patent NZ-544437-A (NZ)
Title: Modular fence with snap fit of pickets into rails
Inventor: ZHU ALAN QING
IPC: E04H17/14
Filed: 2003-12-19
Abstract: A modular picket fence including a pair of vertical posts (12, 14) positioned at suitable distance. A pair of horizontal upper and lower hollow rails (18, 22) extend between the vertical posts. The upper rail has a plurality of apertures (30), which are aligned with a plurality of apertures (30) on the lower rail. Hollow vertical pickets (16) are inserted into the rail apertures. The end portion of each vertical picket has two transverse apertures (32, 34). A locking member (40) in the form of a U-shaped spring clip is assembled inside each end portion of the vertical picket. The locking member has spring biased stoppers (44) extending through the transverse apertures at the end portion of the vertical picket, and further extending inside the horizontal rail when the end portion of the vertical picket is inserted into one of the apertures of the horizontal rail, thereby preventing vertical movement of the vertical pickets with respect to the horizontal rails.
Patent NZ-544608-A (NZ)
Title: Pharmaceutical compositions having a swellable coating comprising prolamin
Inventor: SRINIVAS IRUKULLA
IPC: A61K9/22
Filed: 2004-07-16
Abstract: Disclosed is a pharmaceutical dosage form comprising: a solid core comprising a pharmaceutical active and a disintegrant; a swellable coating comprising a prolamine surrounding the core; and an enteric coating surrounding the swellable coating.
Patent NZ-546365-A (NZ)
Title: Modulators of ATP-binding cassette transporters containing cycloalkyl or pyranyl groups
Inventor: HADIDA RUAH SARA S
IPC: C07C233/11
Filed: 2004-10-08
Abstract: Disclosed is a compound of formula II wherein A is C(O) or SO2, RC and RD taken together form a 3-6 membered cycloalkyl ring; RB is (C1-C4)alkoxy, Z is a substituent of formula I and wherein the rest of the substituents are disclosed within the specification. Also disclosed is the modulating ARP- Binding Cassette (ABC) transporter activity of the compound of formula II.
Patent NZ-547380-A (NZ)
Title: A method and system for promoting service providers
Inventor: PLUNKETT BRUCE DAVID
Filed: 2006-06-19
Abstract: An apparatus for promoting service providers comprises: i) means for presenting a plurality of service provider listings to a user; ii) means for publishing within each service provider listing reviews previously received for respective service providers; iii) means for receiving a job request from the user wherein the job request identifying a task to be completed and one of the service providers associated with the service provider listings; iv) means for transmitting a Job notification to the service provider identified in the job request wherein the job notification including at least the task to be completed; v) means for forming, upon receiving an acceptance notification from the service provider identified in the job request, a job contract; vi) means for receiving a further service provider review from the user upon completion of the job contract; and vii) means for updating the service provider listing of the service provider associated with the further service provider review.
Patent NZ-549554-A (NZ)
Title: Combination therapy involving 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline (AZD2171) and a taxane
Inventor: WEDGE STEPHEN ROBERT
IPC: A61K31/337
Filed: 2005-03-22
Abstract: Disclosed is the use of AZD2171 (4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline) or a pharmaceutically acceptable salt thereof excluding an AZD2171 maleate salt, and a taxane (such as paclitaxel or docetaxel) in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human. Also disclosed is the use of the above combination in the manufacture of a medicament for use in the production of an anti-cancer effect (including an anti-tumour effect) in a warm-blooded animal such as a human. In addition, a pharmaceutical composition which comprises AZD2171 or a pharmaceutically acceptable salt thereof excluding an AZD2171 maleate salt, and a taxane in association with a pharmaceutically acceptable excipient or carrier is also disclosed, as is a kit comprising AZD2171 or a pharmaceutically acceptable salt thereof and a taxane.
Patent NZ-550797-A (NZ)
Title: Pharmaceutical combinations containing 6-hydroxy-8-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1,1-dimethylethylamino]-ethyl}-4H-benzo[1,4]oxazin-3-one for treating respiratory diseases
Inventor: BOUYSSOU THIERRY
IPC: A61K45/00
Filed: 2005-04-18
Abstract: Disclosed is a medicament combination which comprises 6-hydroxy-8-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1,1-dimethylethylamino]-ethyl}-4H-benzo[1,4]oxazin-3-one (as represented by the formula 1.5) and one or two compounds as another active substance 2 selected from anticholinergics (2a) and steroids (2c); wherein any anticholinergic (2a) is selected from the group comprising tiotropium salts (2a.1), oxitropium salts (2a.2), flutropium salts (2a.3), ipratropium salts (2a.4), glycopyrronium salts (2a.5), trospium salts (2a.6) and any steroid 2c is selected from the group comprising prednisolone (2c.1), prednisone (2c.2), butixocortpropionate (2c.3), flunisolide (2c.5), beclomethasone (2c.6), triamcinolone (2c.7), budesonide (2c.8), fluticasone (2c.9), mometasone (2c.10), ciclesonide (2c.11), rofleponide (2c.12), dexamethasone (2c.14), (S)-fluoromethyl 6a,9a-difluoro-17a-[(2-furanylcarbonyl)oxy]-11b-hydroxy-16a-methyl-3-oxo-androsta-1,4-diene-17b-carbothionate (2c.15), (S)-(2-oxo-tetrahydro-furan-3S-yl) 6a,9a-difluoro-11b-hydroxy-16a-methyl-3-oxo-17a-propionyloxy-androsta-1,4-diene-17b-carbothionate (2c.16) and etiprednol-dichloroacetate (2c.17), optionally in the form of a racemate, enantiomer or diastereomer thereof and optionally in the form of a salt or functional derivative thereof, solvate and/or hydrate thereof. Also disclosed is the use of a medicament combination as defined above for preparing a pharmaceutical composition for the treatment of inflammatory and obstructive respiratory complaints (such as obstructive pulmonary diseases of various origins, pulmonary emphysema of various origins, restrictive pulmonary diseases, interstitial pulmonary diseases, cystic fibrosis, bronchitis of various origins, bronchiectasis, ARDS (adult respiratory distress syndrome) and all forms of pulmonary oedema , bronchial asthma, paediatric asthma, severe asthma, acute asthma attacks, chronic bronchitis and COPD (chronic obstructive pulmonary disease)).
Patent NZ-551732-A (NZ)
Title: Carboranylporphyrins and uses thereof
Inventor: WU HAITAO
IPC: A61K41/00
Filed: 2005-05-17
Abstract: Disclosed are carboranylporphyrin compounds of formula (I) wherein at least one of Y1, Y2, Y3 or Y4 is represented by a compound of formula (2), wherein the compound of formula (2) is -X-(CR1R2)r-Z, and the rest of the substituents are defined within the specification. Also disclosed is the use of the said carboranylporphyrin compounds in the manufacture of a medicament for bimodal cancer treatment.
Patent NZ-554895-A (NZ)
Title: Transcriptome microarray technology and methods of using the same
Inventor: HARKIN PAUL
Filed: 2005-11-03
Abstract: Disclosed is a microarray comprising a collection of biological molecule probes capable of binding to substantially all of the gene products transcribed in a diseased tissue, wherein the probes are bound to a solid substrate.
Patent NZ-560253-A (NZ)
Title: Fluid supply assembly with measuring guide
Inventor: KOSMYNA MICHAEL J
IPC: G01F23/04
Filed: 2006-01-25
Abstract: A sliding measuring scale for measuring fluid components inside a fluid container. The measuring guide is fitted on the container lid. A method for using such measuring guide is also described.
Patent NZ-570084-A (NZ)
Title: Inhibitors of E1 activating enzymes
Inventor: LANGSTON STEVEN P
IPC: C07H19/14
Filed: 2007-01-31
Abstract: Disclosed is a compound of formula (I), where ring A is a multi-nitrogen bicyclic ring and where the other substituents are as defined in the specification. Also disclosed are intermediates useful for preparing the compound. Also disclosed is the use of the compound for inhibitng E1 enzyme activity, and for treating cancer, immune response disorder, or vascular cell proliferation disorder.
Patent NZ-572350-A (NZ)
Title: An isolated dna fragment of the sparc human promoter and its use
Inventor: PODHAJCER OSVALDO LUIS
IPC: A61K39/12
Filed: 2007-04-26
Abstract: Disclosed is an isolated DNA of a nucleic acid promoter having a sequence consisting of SEQ ID NO: 1. Also disclosed is an expression vector comprising the said isolated DNA and a heterogeneous gene operably linked thereto. Further disclosed is a pharmaceutical composition comprising the expression vector and the use of the pharmaceutical composition in the manufacture of a medicament for the treatment of a tumor in a patient suffering there from.
Patent NZ-584117-A (NZ)
Title: Antibodies binding to EphB4 for inhibiting angiogenesis and tumor growth
Inventor: KRASNOPEROV VALERY
IPC: A61K39/395
Filed: 2005-03-11
Abstract: Disclosed is an isolated antibody or antigen binding portion thereof that binds to an epitope situated within amino acids 324-429 or 430-537 of the extracellular portion of EphB4; and stimulates EphB4 kinase activity; and promotes apoptosis in a tumor cell.
Patent NZ-585405-A (NZ)
Title: Hydraulically Damped Door Hinge For Glass Doors With Multiple Stop Positions
Inventor: CHOW CHUNG
IPC: E05D7/02
Filed: 2010-05-17
Abstract: A glass door hinge having an internal door stop arrangement includes a housing 1, a mount 2 for coupling the housing to a support member, a pair of clamps 5, an axial spindle 6, and a plurality of biasing members 16 to 26 and 27 to 38 arranged to engage the spindle to return the clamps to one of a plurality of positions selected from a closed position and one or more opened positions. Each biasing member includes a damper to limit the rate of rotation of the hinge. The damper includes a piston 16, 27 mounted in a cylindrical bore for movement radially with respect to the spindle. The spindle has a plurality of centering surfaces 11, 12 rotationally offset to one another, each surface being associated with one of the biasing members which are arranged to engage and apply a force to a respective centering surface to centre the clamps in one or more of said positions. At least one of said pistons 16 has a head and a cylindrical body dimensioned to be slidably received within a cylindrical bore of a cylindrical sleeve, and one or more apertures 34 provided at a predetermined axial distance from the head, the aperture or apertures being blocked by the sleeve after sliding the body by a predetermined distance into the sleeve, and a cut-away portion 42 extends to the distal end of the cylindrical body of at least one of the pistons of the biasing members.
Patent NZ-588515-A (NZ)
Title: Wind power installation with busbar elements pre-installed in pylon segments
Inventor: KNOOP FRANK
IPC: F03D1/00
Filed: 2009-04-09
Abstract: A wind energy system comprising a tower made up of a plurality of tower segments (21, 22), a generator disposed in the area of the top of the tower, a power module disposed in the area of the tower base or separate from the tower, busbar elements (91, 98) which are pre-installed in the associated tower segments in a segmented manner for transferring current from the generator to the power module, and connection elements (13) for connecting busbar elements which are pre-installed in adjacent tower segment. Clamp supports (10) are attached to the inner wall in the lower end area of the tower segments in the assembled state. The busbar elements are pre-installed in the respective associated tower segments, with end sections (200) of the busbar elements being clamped or inserted into the clamp supports.
Patent NZ-591006-A (NZ)
Title: A collagen scaffold for cell growth and a method for producing same
Inventor: ZHENG MING HAO
IPC: A61L27/24
Filed: 2009-07-24
Abstract: Disclosed is a bioscaffold comprising greater than 80% type I collagen fibers or bundles having a knitted structure and a modulus of greater than 300 MPa. Further disclosed is a bioscaffold comprising greater than 80% type I collagen fibers or bundles having a knitted structure and has an extension at maximum load of less than 85%.
Patent NZ-600702-A (NZ)
Title: Systems and methods for ex-vivo organ care
Inventor: HASSANEIN WALEED
IPC: A01N1/02
Filed: 2005-10-07
Abstract: 600702 A disposable pump interface assembly (300) is disclosed for pumping organ perfusion fluid. The assembly (300) is removable from a pump driver in an organ care system that maintains an organ in a physiological state. The pump interface assembly comprises a housing (302) including an exterior (304) and an interior. A first deformable membrane is in fluid tight interconnection with the interior of the housing (302) to define a chamber. The housing (302) is configured to removably dock with the pump driver by way of a flange (328) extending from the exterior of the housing (302) configured to mate with a slot in the pump driver assembly and a projection (323) configured to abut one or more surfaces of the pump driver to force the housing toward the pump driver assembly when rotated. The pump (300) further includes a fluid inlet (308) and a fluid outlet (310). Fluid is expelled from the chamber in response to the pump driver deforming the membrane toward the interior side of the housing (302) and enters the chamber in response to the pump driver moving away from the interior side of the housing. The pump interface may be used in a system where the organ care system and the pump driver assembly can be reused more than once and the pump interface (300) and housing (302) can be discarded after a single use.
Patent NZ-602897-A (NZ)
Title: Raav-guanylate cyclase compositions and methods for treating leber’s congenital amaurosis-1 (lca1)
Inventor: HAUSWIRTH WILLIAM W
IPC: C12N9/88
Filed: 2011-04-22
Abstract: Disclosed is a recombinant adeno-associated viral (rAAV) vector comprising at least a first polynucleotide that comprises a photoreceptor-specific human rhodopsin kinase promoter, or a ubiquitous truncated chimeric CMV-chicken b-actin promoter, operably linked to at least a first nucleic acid segment that encodes at least a first biologically-active, retinal-specific human guanylate cyclase protein, peptide, or polypeptide that comprises at least a first contiguous amino acid sequence region that is at least about 95% identical to an at least 120 contiguous amino acid sequence from SEQ ID NO:1.
Patent NZ-609775-A (NZ)
Title: Improved process for recovering sugars from a pretreatment stream of lignocellulosic biomass
Inventor: ORIANI LUIS
IPC: D21C1/02
Filed: 2011-09-29
Abstract: Disclosed herein is a process for the soaking of lignocellulosic biomass, comprising the steps of: A) introducing a lignocellulosic biomass feedstock into a first soaking zone; B) soaking the lignocellulosic biomass feedstock in the presence of water or water vapor for a first time and a first temperature correlating to a first severity of the soaking conditions creating a first liquid comprised of at least one compound selected from the group consisting of acetic acid, glucose, xylose and soluble oligomers thereof; C) separating at least a portion of the first liquid comprised of the at least one compound selected from the group consisting of acetic acid, glucose, xylose and soluble oligomers thereof from the biomass of the first soaking; D) introducing the biomass of the first soaking zone into a second soaking zone in the presence of water for a second time and a second temperature correlating to a second severity of the soaking conditions creating a second liquid comprised of at least one compound selected from the group consisting of acetic acid, glucose, xylose and soluble oligomers thereof, wherein the second severity is greater than first severity; E) separating at least a portion of the second liquid comprised of the at least one compound selected from the group consisting of acetic acid, glucose, xylose and soluble oligomers thereof from the biomass of the second soaking.
Patent NZ-610431-A (NZ)
Title: Rescue descender system
Inventor: JONES OWAIN
IPC: A62B1/14
Filed: 2011-11-18
Abstract: A descender device (1) is disclosed for use in a fall arrest system. The device includes a descent line (23) and a release element (19) connected to a binding line (4). The release element (19) releases the binding line when actuated by a user to allow descent. A restraint arrangement (4, 8, 11) is arranged to clamp or pinch a length of flexible line (4) which is passed between a plurality of bars (11) in a serpentine manner to arrest the fall, the descent line (23) is then deployed via the release element to lower the user after the fall has been arrested.
Patent NZ-618430-A (NZ)
Title: Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use
Inventor: PANITCH ALYSSA
IPC: C08B37/08
Filed: 2012-05-24
Abstract: Discloses a hyaluronic acid-binding synthetic peptidoglycan comprising a glycan and 1 to 20 synthetic peptides conjugated to the backbone of the glycan, wherein each synthetic peptide is 5 to 40 amino acids in length and can bind to a hyaluronic acid. Further discloses an engineered collagen matrix comprising the same, and use of such compositions to treat arthritis.
Patent NZ-623528-A (NZ)
Title: Orally administered adsorbent
Inventor: NISHIWAKI YASUMI
IPC: C01B32/336
Filed: 2012-10-05
Abstract: Disclosed is an orally administered adsorbent comprising activated carbon fiber for absorbing or removing toxic substances from the body. Also disclosed is the use of the orally administered adsorbent comprising activated carbon fiber, wherein the orally administered adsorbent is a drug for treating or preventing kidney disease, or a drug for treating or preventing dialysis complications by absorbing uremic toxins from the body.
Patent NZ-623817-A (NZ)
Title: Composition to be applied to the skin, and use thereof
Inventor: NAHAVANDI ALI
IPC: A61K47/44
Filed: 2012-09-10
Abstract: Disclosed herein is a composition to be applied to the skin, which comprises a dermatologically compatible vehicle, coconut oil, hazelnut oil and/or avellana oil, and stinging nettle oil. Also disclosed is the use of composition for the treatment of skin diseases such as psoriasis, dermatitis, uriticaria, erythema, lichen planus as well as wounds, burns and corns.
Patent NZ-623854-A (NZ)
Title: Deicing composition comprising molasses and lignin derivative
Inventor: DEMMER RENÉ LODEWIJK MARIA
IPC: C09K3/18
Filed: 2012-11-02
Abstract: Disclosed is a deicing composition comprising (i) a deicing agent selected from the group consisting of sodium chloride, calcium magnesium acetate, calcium chloride, magnesium chloride, potassium chloride, potassium acetate, sodium acetate, sodium formate, potassium formate, (ii) a lignin derivative, and (iii) molasses. The deicing composition remains effective over a longer period of time, so that the deicing agent can be applied less frequently and the damage to especially highly porous road surfaces will be reduced. Also disclosed is a process for preparing the deicing composition and to a process for deicing a surface using the deicing composition. In certain embodiments the lignin derivative is lignosulphonate. In certain embodiments the molasses is selected from the group consisting of molasses derived from corn (syrup), sugar beet, sugar cane, and grapes.
Patent NZ-628270-A (NZ)
Title: Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom
Inventor: MINKE JULES MAARTEN
IPC: A61K39/39
Filed: 2013-02-14
Abstract: Disclosed is a composition comprising: (a) an expression vector comprising a polynucleotide encoding both: i. a Rabies G polypeptide; and ii. an OX40L polypeptide; and (b) a pharmaceutically or veterinarily acceptable vehicle, diluent or excipient.
Patent NZ-706412-A (NZ)
Title: Container having a use-evident device
Inventor: SMITH ROGER P
IPC: B65D55/02
Filed: 2013-10-17
Abstract: A product includes an indicator (14; 114; 214; 314; 414; 514) at least a portion of which is carried by a container (12; 112;. 212; 312; 412; 512) and responsive to a change in at least one state of the container to irreversibly modify a visual characteristic visible from outside the container. The product addresses the issue of repackaging of containers with counterfeit products by providing a use indicator carried by the container to indicate whether the container has been used.