Patent SG-11201406978R-A (SG)
Title: Stable polymerizable uv-absorbing colorant for intraocular lens
Inventor: TAMURA MASAHIRO
IPC: C09B29/12
Filed: 2013-04-30
Abstract: (i2) mwu ft iz s-5 iv x m £ titz s issaj n d9) mm IHMMi _ (43) 2013 ^ 10 ^ 31 0 (31.10.2013) I P O I P C T (10) WO 2013/162042 A1 A61L 27/00 (2006.01) C08F 20/56 (2006.01) PCT/JP2013/062537 2013^4^ 30 0(30.04.2013) (51) C09B 29/12 (2006.01) A61F 2/16 (2006.01) (21) (22) (25) (26) @U8&M©Wi§: (30) fiBfcftf '— 1 £: 4#Jg| 2012-102960 2012 ^ 4 ^ 27 0(27.04.2012) JP (71) ttiHA _m $ P itjK tt (KOWA COMPANY, LTD.) [JP/JP]; T 4608625 ^£P!ft:S\"S'JIrfT4l*i$HTg ] 6§2 9-^ Aichi (JP). (72) % BJ # : H ft IE £ (TAMURA, Masahiro); T 4178650 if H!ftii±rtT;*:Sr§TH 3 2 3 - 1 ® H±EjF5bfi)jF*q Shizuoka (JP). IT PiH(OSHITA, Takahide); T4178650 IIH!fts±rfT x&mm 332-1 fill 1^3 Shizuoka ( JP) . (74) ftHAJHP Mi., ^1- (K A A W G U C HI, Yoshiyuki et al.); T 1030004 B 3TI4 |1 0^ 7^P^°'JX2 1 t*jl/6P§ Tokyo (JP). (8i) Jt^ia (^ro&i^PBy > IS nj f b): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) (asrofci^isy > ±T(Dmm(Dfcm% 11^ nlfb): ARIPO (BW, GM, KE, GH, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), 3. — =j V T (AM, AZ, BY, KG, KZ, RU, TJ, TM), 3 — • V / ^ (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). - mmmi 21 ^(3)) (54) Title: STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS = (54)f§BJ<Z)£^:S££:S£l*IU>Xffl1 (1) CJ •t o CJ i-H en i-H o CJ o £ (2) (57) Abstract: Provided is a polymerizable UV-absorbing colorant monomer which exhibits excellent stability under alkaline conditions and which is for a polymer that is use­ ful as an intraocular lens material. A compound represen­ ted by general formula (1) is used as a polymerizable UV- absorbing colorant monomer for a polymer for an intraocu­ lar lens material. Formula (1) (In general formula (1), R 1 is a hydrogen atom, a hydroxy group, a carboxy group, an al- kyl group having 1-8 carbon atoms, an alkoxy group hav­ ing 1-8 carbon atoms, a sulfonic acid group or a benzyloxy group, R 2 is a hydrogen atom, hydroxy group a or an al­ koxy group having 1-4 carbon atoms, and R 3 is represented by formula (2). Formula (2) (In general formula (2), R 4 is a hydrogen atom or a methyl group. In addition, R 5 is a single bond or an optionally substituted alkylene group having 1-4 carbon atoms). (57) T u tUstsXmW&tZ'J-Z—CDtztibO) • IB—ISsC (1) lQ 3; XfflW&yK'J -?-(DtzSb(D =ES^—tt& 0 3: (1) (Hfta (1) R'lt t h'P+vl, 5S> ifcMgfi: 1 ~ 8CD7,/l/dr,/H£ > 0)7)1- 1+vI, t Kn+i/i, Sf=iiJKSiai ~ 4 y, R I£, 3 T (—HS3; (2) R 4 li7K^Jl^ TJU&Vfo&o R 5 Tt-JrvST-fey, R 2 l£7KltJI^ IB5C (2) ) it (2)