baber/WOPTO huggingface dataset:
Patent EP-4100406-A1 (EP)
Inventor: GURKAN SEVGI
IPC: C07D413/12
Filed: 2021-02-03
Abstract: The present disclosure relates to the discovery that certain ocular diseases may be treated using Edonentan crystalline forms. Specific Edonentan crystalline form can be used alone or in combination with an intra-ocular pressure (IOP) reducing agent, a neuroprotective agent, or an anti-VEGF agent. Using Edonentan crystalline forms, alone or in combination with an additional agent, provides increased perfusion to the retina or reduced IOP in certain ocular diseases and reduces damage to retinal cells.
Patent EP-4103231-A1 (EP)
Inventor: HAUSER MARY JO
IPC: C07K14/165
Filed: 2021-02-12
Abstract: Provided herein are recombinant modified vaccinia Ankara (rMVA) viral vectors comprising heterologous nucleic acid inserts encoding one or more SARS-CoV2 proteins, peptides, or fragments thereof, operably linked to a promoter compatible with poxvirus expression systems that, upon expression, are capable of inducing protective immunity. The compositions can be used in a priming vaccination strategy or in a prime/boost vaccination strategy to provide immunity to SARS-CoV2 and variants thereof.
Patent EP-4185389-A1 (EP)
Inventor: GALLE FRANCIS
IPC: A61K8/44
Filed: 2021-07-16
Abstract: L'invention a pour objet une composition tensioactive renfermant au moins un sel d'ester ou d'amide de glycine bétaïne, ou une composition dermatologique la contenant, pour son utilisation comme agent pédiculicide par application topique sur les cheveux et le cuir chevelu. Elle a également pour objet un procédé pour prévenir et/ou traiter les infestations par les poux de tête et/ou les lentes, comprenant l'application sur une surface en tissu d'une composition topique renfermant une composition tensioactive telle que définie ci- dessus.
Patent EP-4189742-A1 (EP)
Inventor: DECKERS MICHAEL
IPC: H01L33/00
Filed: 2021-07-28
Abstract: L'invention concerne un procédé d'assemblage d'au moins un élément d'éclairage (22) sur un substrat (40). Le procédé consiste à : pré-assembler au moins un élément d'éclairage (22) sur un support temporaire (10) qui est ou comprend une bande ; pré-assembler au moins un élément de référence (30) ayant une épaisseur supérieure ou égale à celle de l'au moins un élément d'éclairage sur le support temporaire ; aligner le support temporaire pré-assemblé sur le substrat sur la base, au moins en partie, sur l'au moins un élément de référence du support temporaire ; et monter l'au moins un élément d'éclairage sur le substrat. L'invention concerne également un substrat (40), le substrat comprenant : au moins un élément d'éclairage (22), ledit au moins un élément d'éclairage étant assemblé sur le substrat, en particulier par un procédé selon l'aspect ci-dessus. L'invention concerne également l'utilisation du procédé ci-dessus pour assembler au moins un élément d'éclairage (22).
Patent EP-4188844-A1 (EP)
Inventor: BIONDI ANDREA
IPC: B65B29/02
Filed: 2021-07-26
Abstract: L'invention concerne une unité d'amenée (1 ; 100) pour des articles (2), comprenant un premier dispositif d'amenée (4 ; 104), un deuxième dispositif d'amenée (6 ; 106), qui est prévu pour ramasser individuellement les articles (2) à partir du premier dispositif d'amenée (4 ; 104) au niveau d'un emplacement de retrait (P) et à un intervalle de temps prédéterminé, ainsi qu'un dispositif de synchronisation (5 ; 105) qui est prévu pour recevoir les articles de la part du premier dispositif d'amenée (4 ; 104) et pour les déplacer dans l'emplacement de retrait (P). Un système de commande (13 ; 113) est prévu pour régler la vitesse du dispositif de synchronisation (5 ; 105), de sorte que chaque article (2) atteigne l'emplacement de retrait (P) à l'intervalle de temps prédéterminé afin d'être ramassé par le deuxième dispositif d'amenée.
Patent EP-4107440-A1 (EP)
Title: Installation frame of an exhaust blower of a building and exhaust air control system
Inventor: POHJALAINEN AKI
IPC: F24F11/77
Filed: 2021-02-17
Abstract: In the solution put forth, there is a frame structure (122) and an inner surface structure (124) in an installation frame (110) of an exhaust blower (108) of a building (100). A bottom part (130) of the frame structure is intended to be installed towards a lead-through (106) of the building, and a top part (132) towards the exhaust blower installed over it. The frame structure surrounds the inner surface structure so that it does not cover bottom and top parts (126, 128) of the inner surface structure. The inner surface structure forms a suction channel (134) allowing exhaust air (114) flow through the frame. Inside the installation frame, a controller (112) has been installed, adapted to measure the exhaust air flowing in the suction channel and to generate, on the basis of the measurement, a control command for the exhaust blower to control the operation of the exhaust blower.
Patent EP-4108670-A1 (EP)
Inventor: OBIKA SATOSHI
IPC: C07H21/00
Filed: 2021-02-18
Abstract: Disclosed are a bridged nucleoside and a nucleotide using the same. The nucleoside of the present invention is represented by the formula (I) below. The bridged nucleoside of the present invention is usable as a substitute for a phosphorothioate-modified nucleic acid, which has a risk of, for example, accumulation in a specific organ. The bridged nucleoside also has excellent industrial productivity.
Patent EP-4112545-A1 (EP)
Inventor: SHIBUYA AKIYOSHI
IPC: C01B32/162
Filed: 2021-02-15
Abstract: A production method for growing a carbon nanotube assembly on a substrate having a catalyst on a surface thereof. In this production method, in each of a formation unit that carries out a formation step of reducing a catalyst on the substrate and a growth unit that carries out a growth step of growing a carbon nanotube assembly, the substrate is continuously being conveyed using conveyance units that convey the substrate by screw rotations. In carrying out the formation step and the growth step, these steps are carried out while the gas environments in these steps are prevented from mixing with each other.
Patent EP-4200618-A1 (EP)
Title: Reagent container cap, reagent container unit and reagent kit
Inventor: KRAMNY DETLEV
IPC: B01L3/00
Filed: 2021-08-20
Abstract: A Reagent container cap (116) is adapted to being mounted to a reagent container and to being adjustable, at least after an initial opening of the cap (116), between an opened state and a closed state, wherein the reagent container cap (116) defines a cap interior space (109) and has a cap opening (116o) allowing access to the cap interior space (109) from above when the cap (116) is in the opened state; and wherein, in the closed state of the cap (116), the cap interior space (109) is open only towards a bottom side (116b), wherein the reagent container cap (116) comprises a main portion (116m) and an insert portion (116i) that are fixedly connected to each other and made from different materials, wherein, when the cap (116) is in the closed state, the cap interior space (109) comprises a region (109t) which is delimited circumferentially and towards the upper side of this region completely and exclusively by surfaces of the insert portion (116i).
Patent EP-4129103-A1 (EP)
Inventor: TAKAHASHI HISAYA
IPC: A41D19/04
Filed: 2021-03-19
Abstract: Provided are an anti-slipping structure for a surface of an article where dust is minimally filled in recessed portions and a larger friction force can be generated compared to anti-slipping obtained by a powder adhesion method, an article provided with a coating film layer imparting an anti-slipping effect, an anti-slipping body, gloves, a method for manufacturing gloves and the like.An article has a coating film layer that covers the article. A plurality of recessed portions are formed on the coating film for imparting an anti-slipping effect to the article. The plurality of recessed portions are formed of: a plurality of hemispherical recessed portions having an approximately circular shape as viewed in a plan view; and a plurality of diaphragm provided recessed portions formed such that two or more hemispherical recessed portions are connected to each other in a partially overlapping manner and a connection boundary between the recessed portions is partitioned by a diaphragm. In a method for forming a coating film layer which covers a surface of an article and on which a plurality of recessed portions are formed so as to impart an anti-slipping effect to the article, wherein a liquid droplet of a solidifying agent is made to impinge on an unsolidified elastic material that adheres to the surface of the article so as to recess and solidify impinged portions thus forming the recessed portions.
Patent EP-4216921-A1 (EP)
Inventor: CLAYPOOL JOSHUA
IPC: A61K8/9789
Filed: 2021-09-17
Abstract: La présente invention concerne un extrait d'Epilobium, de préférence un extrait d'Epilobium fleisceri, destiné à être utilisé en tant que prébiotique.
Patent EP-4213683-A1 (EP)
Inventor: LEFEBVRE BENOIT
IPC: A45D19/04
Filed: 2021-09-17
Abstract: The invention relates to a portable device for washing and styling hair, comprising a washing compartment (100) which comprises an open-topped hollow body (110) and is provided with a receiving collar (116) for the neck, a holder (400) which is movable between a stowed storage position and a deployed service position wherein it is capable of supporting the compartment (100) above ground, as well as a cover that can be fixedly and removably mounted on top of the compartment (100) so as to constitute a utility table during the hair styling phase; characterised in that the holder (400) can be removably mounted on the compartment (100), said holder (400) furthermore being capable of being entirely housed inside said same compartment (100) in its stowed storage position.
Patent EP-4225844-A1 (EP)
Inventor: DELEVATI GIANCARLOS
IPC: C08L23/08
Filed: 2021-09-28
Abstract: Une composition polymère peut comprendre un ou plusieurs copolymères d'éthylène-acétate de vinyle (EVA) en une quantité allant de 65 à 95 % en poids; et un élastomère en une quantité allant de 5 à 35 % en poids. Les articles préparés à partir de cette composition de polymère peuvent comprendre des semelles de chaussure, des semelles intercalaires, des semelles extérieures, des monosemelles, des semelles intérieures, des sandales monoblocs, des tongs, des chaussures entièrement en EVA ou des articles de sport.
Patent EP-4139508-A1 (EP)
Title: Comprehensive polygenic risk prediction for breast cancer
Inventor: GALLAGHER SHANNON
IPC: C40B30/00
Filed: 2021-04-16
Abstract: Provided herein are methods for determining a polygenic risk score and breast cancer estimated risk for medical use, as well as for treating breast cancer. Methods of this invention can provide a polygenic risk score which takes into account a plurality of breast cancer associated SNP markers. Also provide is a comprehensive breast cancer risk estimation with increased accuracy.
Patent EP-4213887-A1 (EP)
Inventor: WYCOFF KEITH
IPC: A61K47/68
Filed: 2021-09-15
Abstract: La présente divulgation concerne de manière générale des fusions de protéines du facteur H (FH) et de Fc, les fusions comprenant divers lieurs, des acides aminés N-terminaux supplémentaires, et d'autres variants de la structure linéaire et des séquences d'acides aminés qui fournissent l'efficacité microbicide et/ou la fabricabilité améliorées des protéines. La présente divulgation concerne également des compositions comprenant ces fusions de protéines ou leurs séquences polynucléotidiques codantes, des méthodes pour leur préparation, y compris la production recombinante dans des hôtes végétaux, et l'utilisation de ces fusions de protéines pour la réduction ou l'éradication de microbes pathogènes dans des organismes, y compris un traitement prophylactique ou thérapeutique de mammifères, tels que des êtres humains, pour des maladies provoquées par des microbes pathogènes, y compris la maladie de Lyme.
Patent EP-4232391-A1 (EP)
Title: A drive nut for moving a platform of a platform elevator
Inventor: THÅRLIN BENGT-ÅKE
IPC: B66B9/02
Filed: 2021-10-22
Abstract: The present disclosure relates to a drive nut (50) for moving a platform (14) of a platform elevator (10), wherein the width (wl) of a nut thread lower flank (56) decreases in the vicinity of an upper nut end (51) in direction from a lower nut end (52) towards the upper nut end (51). Thereby, wear of the underside of the nut thread lower flank (56) against an irregularity between adjacent platform elevator screw sections (20a, 20b; 61a, 61b) is facilitated. The present disclosure further relates to a platform elevator, to a method of adapting a platform elevator drive nut (50), to the use of a drive nut (50), and to an arrangement of a drive nut (50) and a threaded screw (60).
Patent EP-4228438-A1 (EP)
Inventor: BERTOCCHI ALESSANDRO
IPC: A23N1/02
Filed: 2021-10-15
Abstract: Plant (1) for producing juice and/or puree from a food product of vegetable origin comprising a treating section (10) configured in such a way that the quantity of the food product that is introduced is equal to the quantity of discharged treated product and comprising a fixed hollow body (13) having a substantially cylindrical or conical shape having a predetermined length (L) and provided with a treating surface (14). Within the treating section (10) a first rotor (15) is provided also this having a substantially cylindrical or conical shape. The fixed hollow body (13) and the rotor (15) are configured in such a way that the treating surface (14) is positioned at a first distance (dl) from the first rotor (15) at an inlet end (10a) less than, or equal to 100 mm, i.e. dl≤100 mm, and at a second distance (d2) with d2<dl, at an outlet end (10b). Downstream of the treating section (10) a division section (20) is provided configured to divide a food product of vegetable origin (100) into a plurality of pieces (101) having at least a dimension with a length equal to, or less than, the first distance (dl) in order to easily feed them into the treating section (10).
Patent EP-4145729-A1 (EP)
Inventor: LV JINGFEI
IPC: H04J3/06
Filed: 2021-05-18
Abstract: This application discloses a port status configuration method, apparatus, and system, and a storage medium, and belongs to the communication field. The method includes: A configuration device obtains port datasets of M ports of N translators, where N is an integer greater than 1, M is an integer greater than 1, the N translators are integrated in at least two independent devices, the M ports are M precision time protocol ports, and the port datasets are precision time protocol port datasets. The configuration device configures port statuses of the M ports based on the port datasets of the M ports, where the port statuses are precision time protocol port statuses. This application achieves automatic configuration of the port statuses and improves configuration accuracy.
Patent EP-4144727-A1 (EP)
Inventor: ZOU JUN
IPC: C07D401/04
Filed: 2021-08-16
Abstract: A method for preparing chiral synthetic nicotine includes the following steps: Step S1. condensing nicotinic acid ester and γ-butyrolactone under the action of alkaline condensate in organic solvent I to obtain the first mixture; Step S2. performing a ring-opening reaction to the first mixture obtained in Step S1 by adding an acidic substance to obtain a second mixture; Step S3. separating 4-chloro-1-(3-pyridine)-1-butanone from the second mixture obtained in Step S2, reacting with chiral tert-butyl sulfinamide to obtain chiral N-(4-chloro-1-(pyridin-3-yl)butene) -2-methylpropane-2-sulfinamide; Step S4: reacting the chiral N-(4-chloro-1-(pyridin-3-yl) butene)-2-methylpropane-2-sulfenamide with a reducing agent, and then cyclizing under the action of hydrogen halide to obtain a chiral demethylized nicotine; and Step S5: performing methylamination to the chiral demethylized nicotine to obtain a chiral nicotine. The present application achieves the advantages of simple process, easy operation, low cost, high yield, and high ee value, suitable for industrial production.
Patent EP-4248110-A1 (EP)
Title: Koppelvorrichtung zur an- und/oder abkopplung eines zahnrades an eine bzw. von einer welle und ein getriebe mit einer entsprechenden koppelvorrichtung
Inventor: WEISSINGER DANIEL
IPC: F16H63/30
Filed: 2021-11-08
Abstract: Die Erfindung betrifft eine Koppelvorrichtung (10) zur An- und/oder Abkopplung eines Zahnrades (21) an eine bzw. von einer Welle (14) und ein Getriebe, insbesondere für eine elektrische Antriebsanordnung, mit einer entsprechenden Koppelvorrichtung (10).
Patent EP-4248216-A1 (EP)
Inventor: INNOCENZI PAUL
IPC: G01N33/68
Filed: 2021-11-15
Abstract: L'invention concerne des procédés et des produits pour ajuster l'âge chronologique d'un système biologique ou d'un individu pour fournir un aperçu plus fin de l'état de santé. Divers biomarqueurs sériques et urinaires comprenant de l'antistreptolysine sont utilisés dans le cadre des procédés.
Patent EP-4238257-A1 (EP)
Inventor: ZHOU YAN
IPC: H04L1/18
Filed: 2021-10-25
Abstract: Apparatus, methods, and computer-readable media for multiplexing of overlapped uplink channel transmission repetitions are disclosed herein. A user equipment (UE) may determine that at least a portion of a first set of uplink channel transmission repetitions overlaps with at least a portion of a second set of uplink channel transmission repetitions. The UE may modify the first set of uplink channel transmission repetitions based on the second set of uplink channel transmission repetitions. A base station (BS) may transmit a first downlink transmission associated with the first set of uplink channel transmission repetitions that overlaps with at least a portion of a second set of uplink channel transmission repetitions associated with a second downlink transmission. The BS may receive a modified version of the first set of uplink channel transmission repetitions based on the second set of uplink channel transmission repetitions. Thus, the reliability of uplink repetitions can be increased.
Patent EP-4145809-A1 (EP)
Inventor: YANG LIUQING
IPC: H04M1/725
Filed: 2021-03-25
Abstract: This application provides a display control method, an electronic device, and a computer-readable storage medium. The method includes: displaying a multi-task interface if a first touch operation event entered by a user on a touchscreen of the electronic device is detected, where the first touch operation event is used to start the multi-task interface; and displaying a one-hand operation interface on the electronic device if a second touch operation event entered by the user on the touchscreen is detected in the multi-task interface. In this application, the one-hand operation interface can be started more conveniently and quickly, and a misoperation rate can be effectively reduced.
Patent EP-4162187-A1 (EP)
Inventor: WITTE KLAUS H
IPC: F16L33/22
Filed: 2021-06-04
Abstract: A hydraulic coupling system is configured to couple a hydraulic hose to a hydraulic cylinder and includes: a compressive adapter assembly including: a first adapter portion configured to receive a portion of the hydraulic hose, and a second adapter portion configured to engage an inlet tube of the hydraulic cylinder, wherein a first tube portion of the inlet tube of the hydraulic cylinder is configured to be received within a portion of the hydraulic hose; and a compressive sleeve assembly configured to engage the compressive adapter assembly and radially compress the first adapter portion of the compressive adapter assembly onto an outer surface of the portion of the hydraulic hose, thus compressing an inner surface of the portion of the hydraulic hose onto the first tube portion of the inlet tube of the hydraulic cylinder.
Patent EP-4263944-A1 (EP)
Title: Method of repairing bitumen surfaces and device for carrying out this method
Inventor: RUSIKVAS JIRI
IPC: E01C23/06
Filed: 2021-11-29
Abstract: Name: Method of repairing bitumen surfaces and device for carrying out this method The method for repairing bitumen surfaces using microwave heating is carried out so that the area around the defect (24) of the bitumen layer is divided prior to the heating into at least two zones with separate heating through microwave radiation. In the primary heating zone (25), defined by the edge (23) of the defect and its surroundings, delimited by a distance of at least 10 mm on both sides from the edge (23) of the defect, the bitumen layer is heated to a temperature of 70°C to 195°C, and in the secondary heating zone (26) adjacent to the primary heating zone (25) and is at least 10 mm wide, the bitumen layer is heated to 30°C to 110°C The temperature of the primary heating zone (25) is always higher by at least 20°C than the temperature of the secondary heating zone (26). Following the heating of the primary zone (25) and the secondary zone (26) to the desired temperature, the damaged spot is filled with the heated bitumen mixture and the bitumen mixture is compacted to a level with the original surface. A device for carrying out the method includes an application unit (22) comprising a microwave generator (3) and a waveguide (4) thereof, and further comprising a source (2) and a control system, where the microwave generator (3) is coupled to the control unit (1). At least two waveguides (4) terminated by an output chamber (5) and coupled to the microwave generator (3) are divided into at least two independent heating segments (21) for controlled heating of a specific area around the defect (24) in the bitumen layer. On the bottom side of the outlet of each of the waveguides (4) to the output chamber (5) there is a sensor (9) for measuring the temperature of the heated surface connected to the control unit (1). Furthermore, between the casing (8) of the application unit (22) and the frame (6) of the application unit (22) there are drive segments (7) connected to the control unit (1) for controlling the movement of the application unit (22) over the heated surface. The contained microwave oven (14) for heating the bitumen filling mixture is preferably incorporated into a part of the device separate from the application unit (22), where the separate part includes an internal combustion engine (12), a generator (11), a driven (16) and a steering axle (17). The casing (8) of the application unit (22) is provided with at least one sensing camera (20) on its underside.
Patent EP-4271798-A1 (EP)
Title: Compositions and methods for differentiating stem cells into nk cells
Inventor: KYRYCHENKO VIKTORIIA
IPC: C12N5/0783
Filed: 2021-11-30
Abstract: The disclosure features methods and compositions for differentiating stem cells into hematopoietic stem and progenitor cells (HSPC) and/or Natural Killer (NK) cells. The methods and compositions described herein are used to differentiate stem or progenitor cells having at least one gene-edit that is maintained in the differentiated cell. Also provided are differentiated cells produced using the methods and compositions described herein for therapeutic applications.
Patent EP-4169658-A1 (EP)
Inventor: MATSUMURA KOHEI
IPC: B23K26/70
Filed: 2021-05-10
Abstract: [Problem] To reliably force out slag remaining in a hole without damaging protrusions of a table.[Means to Solve Problem] Provided is a laser machining tool that performs laser machining on a plate-shaped workpiece, comprising: a table that has a plurality of protrusions and that supports the workpiece on upper ends of the protrusions; a laser head that performs boring machining by irradiating a laser beam along an outline of a hole to be formed in the workpiece on the table; a transporter that transports the workpiece that has undergone laser machining; and a rod-shaped tool that forces out slag remaining in the hole. The workpiece is transported by means of the transporter until the hole formed by the boring machining is arranged at a processing position having a discharge space for the slag, outside and below the table as seen in a plan view, and the slag remaining in the hole is forced out by means of the rod-shaped tool, at the processing position.