baber/WOPTO huggingface dataset:
Patent CA-2444062-A1 (CA)
Inventor: BECK JURGEN K
IPC: A61K31/198
Filed: 2002-05-10
Abstract: Cette invention se rapport à l'utilisation du 2H-benzimidazole-2-one,1,3-dihydro-1-(2-{4-[3-(trifluorométhyl)phényl]-1-pipérazinyl}éthyl)- ou d'un sel d'addition d'acide de ce composé acceptable sur le plan physiologique, dans la fabrication d'un médicament destiné au traitement des troubles du système extrapyramidal. Ces troubles du système extrapyramidal peuvent résulter de la maladie de Parkinson dans sa forme idiopathique, des effets secondaires de l'administration de médicaments anti-parkinsoniens dans la maladie de Parkinson sous forme idiopathique, des dyskinésies causées par la maladie de Parkinson sous forme idiopathique et/ou de l'administration à long terme de médicaments anti-parkinsoniens, de syndromes du type Parkinson ou apparenté à la maladie de Parkinson ou de symptômes parkinsonoïdes. Un autre aspect de cette invention concerne une composition pharmaceutique contenant, comme principes actifs, (I) du 2H-benzimidazole-2-one,1,3-dihydro-1-(2-{4-[3-(trifluorométhyl)phényl]-1-pipérazinyl}éthyl)- ou un sel d'addition d'acide de ce composé acceptable sur le plan physiologique, et (II) au moins un médicament anti-parkinsonien, associé à un ou plusieurs excipients pharmaceutiquement acceptables.
Patent CA-2445049-A1 (CA)
Title: Rapidly cleavable sumo fusion protein expression system for difficult to express proteins
Inventor: MOSSESSOVA ELENA
IPC: C12N5/06
Filed: 2002-05-06
Abstract: Published without an Abstract
Patent CA-2446889-A1 (CA)
Title: A method for converting a liquid feed material into a vapor phase product
Inventor: MONAGHAN GERARD VINCENT
IPC: B01J8/24
Filed: 2003-10-27
Abstract: A liquid feed material such as a heavy hydrocarbon feed in liquid form is contacted with a fluidized bed of heated solid particles which have a bulk horizontal velocity which is generally perpendicular to the flow of a fluidizing medium. The liquid feed material reacts on the solid particles to produce a vapor phase product, which vapor phase product is collected in a vapor collection apparatus.
Patent CA-2447537-A1 (CA)
Title: Snowmobile suspension system
Inventor: ICHIKAWA MAKOTO
IPC: B62M27/02
Filed: 2003-10-31
Abstract: A snowmobile includes a quadrilateral linkage system formed between a vehicle body frame, a front torque arm assembly, a rear torque arm assembly, and an extendable member. The four-node linkage is coupled with at least one slide rail to provide for the vertical distance between the vehicle body frame and the at least one slide rail to vary. The nodes of the four-node linkage are configured to generally define a quadrilateral shape in at least fully contracted and fully expanded configurations.
Patent CA-2448308-A1 (CA)
Inventor: MAKAROV ALEXANDER ALEKSEEVICH
IPC: H01J49/40
Filed: 2002-05-28
Abstract: An ion detection arrangement (140) for a time-of-flight (TOF) mass spectrometer (10) includes a beam splitter formed as a mesh (150) at the end of the (TOF) acceleration and detection chamber (110). Ions enter the detection arrangement through a common entrance window and are then divided by the beam splitter. Those ions striking the mesh (150) generate secondary electrons (160) which are detected by a microchannel plate forming a first detector (170). Those ions passing through the ion beam splitter are detected directly by a second detector (190) also formed from a microchannel plate. The two detectors are each connected to a corresponding data acquisition system (180,200) and the data obtained by each are combined to generate a mass spectrum. The problems of detector saturation are thus avoided.
Patent CA-2448496-A1 (CA)
Title: Stable transparent perfuming emulsion
Inventor: STORA THIERRY
IPC: A61K8/00
Filed: 2002-05-29
Abstract: A particularly stable perfuming composition in the form of a transparent fluid water-in-oil or oil-in-water emulsion is obtained by addition of a substance to the oily phase, capable of bringing closer the densities of the respective dispersed and continuous phases.
Patent CA-2449786-A1 (CA)
Inventor: KENNEDY THOMAS C
IPC: B65D81/26
Filed: 2002-05-15
Abstract: The present invention relates to the non-invasive use of a luminescent compound to detect and measure concentrations of oxygen dissolved in solids, particularly polymeric materials present in multi-layered packaging material s. The measurement is made independent of the oxygen concentration of the surrounding atmosphere. The invention is especially useful as a quality assurance check to verify oxygen scavenger activation during the assembly of modified atmosphere and vacuum packages. The method according to the inventi on is faster and less wasteful than previous methods that rely on measuring oxygen concentration within the headspace of an assembled package. Novel articles, methods, and packages are also disclosed.
Patent CA-2451981-A1 (CA)
Title: 2,4,5-trisubstituted thiazolyl derivatives and their antiinflammatory activity
Inventor: COOYMANS LUDWIG PAUL
IPC: C07D277/28
Filed: 2002-08-09
Abstract: This invention concerns the use of a compound of formula (I), a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein Z is halo; C1-6alkyl; C1-6alkyl substituted with hydroxy, carboxyl, cyano, amino, mono -or di(C1-6alkyl)amino, aminocarbonyl, mono -or di(C1-6alkyl)aminocarbonyl, C1-6alkyloxycarbonyl or C1-6alkyloxy; polyhaloC1-4alkyl; C1-4alkyloxy; cyano;  amino; aminocarbonyl; mono -or di(C1-6alkyl)aminocarbonyl; C1-6alkyloxycarbonyl; C1-6alkylcarbonyloxy; H2N-S(=O)2-; mono -or di(C1-6alkyl)amino-S(=O)2; -C(=N-Rx)NRyRz; Q is an optionally substituted carbocycle or an optionally substituted heterocycle; L is substituted phenyl or an optionally substituted monocyclic 5 or 6-membered partially saturated or aromatic heterocycle or a bicyclic partially saturated or aromatic heterocycle; aryl is optionally substituted phenyl; for the manufacture of a medicament for the prevention or the treatment of diseases mediated through TNF-.alpha. and/or IL-12.
Patent CA-2452300-A1 (CA)
Inventor: BRICKWOOD MICHAEL JOHN
IPC: A63F3/06
Filed: 2003-12-29
Abstract: A lottery ticket is printed onto a conventional paper, card or similar substrate to provide game information printed on the substrate and game data printed on the substrate where some or all of the game data is covered by a removable covering which can be removed by the player generally by scratching a latex covering layer to expose the covered data for playing the game. In addition, a battery is printed on the substrate together with printed conductive paths, a powered element such lights or sound or a changeable ink formed on the substrate and a switch responsive to an action on the substrate by the player, generally scratching of the covering layer for conducting power from the battery to the powered element.
Patent CA-2453580-A1 (CA)
Title: Detection of ovarian cancer based upon alpha-haptoglobin levels
Inventor: SKATES STEVEN
IPC: G01N33/574
Filed: 2002-06-06
Abstract: The present invention is directed to a method for determining whether a woman has, or is likely to develop, ovarian based upon assays of the alpha subunit of haptoglobin.
Patent CA-2453607-A1 (CA)
Title: Air tunnel diverter and method for installing same
Inventor: JENKINS JAMES H JR
IPC: F25D17/08
Filed: 2002-07-15
Abstract: An air tunnel diverter (10) for a refrigeration unit includes a plurality of leg members (14,16,18) secured to a hub (12). The hub (12) is generally formed to include a fitting (25) through which cooler air is passed to the leg members (14,16,18) and routed into the desired locations within the refrigeration unit. The leg members (14,16,18) are placed on the fitting (25) by sliding one end of the leg members (14,16,18) onto a leg portion (28,30,32) of the fitting (25). The fitting (25) is then secured to the leg members (14,16,18) by an overmolding process in which a soft flexible plastic (34) is cast or otherwise applied around the connection.The air tunnel diverted (10) is preferably secured in the refrigeration unit by foam insulation.
Patent CA-2453848-A1 (CA)
Inventor: DAVIS CLARK
IPC: B26D3/16
Filed: 2002-07-17
Abstract: La présente invention concerne un système de micro-usinage (6) configuré pour couper un objet allongé (8), lequel système comprend : un dispositif de serrage (52) configuré pour pouvoir relâcher et ensuite tenir de façon répétée l'objet allongé dans une position permettant de couper l'objet allongé (8) transversalement par rapport à son axe longitudinal ; et des moyens de manipulation pouvant inclure un dispositif d'avancement de galets de pincement (54) configuré pour faire avancer l'objet allongé (8) et le faire tourner autour de son axe longitudinal, déplaçant de la sorte ledit objet allongé (8) de façon qu'il peut être disposé dans une position adéquate pour la coupe, et un dispositif de coupe (36) configuré pour former au moins une coupure de précision dans l'objet allongé (18) jusqu'à une profondeur désirée, sous la commande d'un contrôleur (80).
Patent CA-2454074-A1 (CA)
Inventor: BROWN LANNY D
IPC: F01P7/16
Filed: 2003-12-23
Abstract: A valve actuating mechanism for a transmission/engine fluid cooler bypass valve of the type in which a responsive element expands to urge a valve member against a valve seat and thereby causes transmission fluid to flow through an oil fluid cooler. A cast valve housing is utilized which is interposed between the cooler and the oil source. The valve actuating mechanism is designed to allow fluid to pass through the valve once the fluid has reached an elevated temperature.
Patent CA-2454637-A1 (CA)
Inventor: KERB REINHOLD
IPC: A61K31/4745
Filed: 2002-07-23
Abstract: The present invention relates to the use of irinotecan or a derivative thereof for the preparation of a pharmaceutical composition for treating colorectal cancer, cervical cancer, gastric cancer, lung cancer, malignant glioma, ovarian cancer, and pancreatic cancer in a patient having a genotype with a variant allele which comprises a polynucleotide in accordance with the present invention. Preferably, a nucleotide deletion, addition and/or substitution comprised by said polynucleotide results in an altered expression of a variant allele compared to the corresponding wild type allele or an altered activity of the polypeptide encoded by the variant allele compared to the polypeptide encoded by the corresponding wild type allele. Finally, the present invention relates to a method for selecting a suitable therapy for a subject suffering from colorectal cancer, cervical cancer, gastric cancer, lung cancer, malignant glioma, ovarian cancer, and pancreatic cancer.
Patent CA-2456412-A1 (CA)
Inventor: BONGINI DINO
IPC: D06F39/02
Filed: 2004-01-28
Abstract: A laundry washing machine comprises a dispenser of washing agents (10) having at least a movable body (26A, 26B, 40) defining a compartment for containing a dose of a respective washing agent. The movable body (26A, 26B, 40) is mounted in a housing (11) in such a way as to be able to assume a first position, for the manual admission of a washing agent into the compartment through a loading mouth (27, 41), and a second position, for withdrawing the washing agent from the compartment by means of a flow of liquid (IN). The movable body (26A, 26B, 40) is pivotally supported in the respective housing (11) to move angularly from said first to said second position and vice versa, around an axis (X) that is substantially perpendicular or otherwise transverse relative to the axis (Y) of the loading mouth (27, 41) of the body (10). Preferably, the movement of the body (26A, 26B, 40) from the first to the second position is obtained by means of the aforesaid flow of liquid (IN).
Patent CA-2456684-A1 (CA)
Title: Manipulation of analytes using electric fields
Inventor: REEL RICHARD
IPC: B01L3/00
Filed: 2002-08-23
Abstract: Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer, etc.) of analytes, e.g., biomolecules, with respect to analyte-containing solutions using one or more electric fields generated by a externally generated electrodes.
Patent CA-2459058-A1 (CA)
Title: Prosthesis shaft comprising a seal
Inventor: CARSTENS FELIX
IPC: A61F2/42
Filed: 2002-08-23
Abstract: A prosthesis shaft (2) is provided with an annular chamber (15) that is located at a distance from its distal end. The annular chamber is formed on the interior of the prosthesis shaft by an adaptable wall (18), which is designed to lie against the exterior of an amputation stump (25). The area between said adaptable wall and the hard prosthesis shaft is aerated by the atmosphere, which causes the adaptable wall to be pressed against the stump by a self-reinforcing, sealing contact force, when a negative pressure arises between the wall and the distal end in the distal region of the prosthesis shaft.
Patent CA-2459700-A1 (CA)
Inventor: MCTAVISH GORDON J
IPC: B65D21/02
Filed: 2004-03-04
Abstract: A baked goods carrier with improved access for automated bread loading has bails with upper legs having a primary axis and an upper extremity with a first bent portion that extends away from the primary axis and a second bent portion that extends back to the primary axis. A longitudinal axis of a horizontal handle member is maintained by the second bent portion in a substantially perpendicular relation to the primary axis.  The horizontal handle member and the second bent portion are positioned within the peripheral walls of the tray when the bails are in the upright position. Confining channels are provided in the floor structure of the tray to prevent relative movement transverse to the axis of the horizontal handle member. Limiting shoulders depend from the floor structure to engage the second bent portion and prevent relative movement along the axis of the horizontal handle member.
Patent CA-2467850-A1 (CA)
Inventor: BENEDETTI STEVEN M
IPC: F16B5/12
Filed: 2004-05-19
Abstract: A one-piece molded apparatus includes a first body section having a head, a skirt, a pair of support posts joined to the skirt, and a first engagement wing. A second body section includes a second engagement wing, and a living hinge joining the second wing to the support posts. The second wing rotates about the living hinge and engages with the support posts such that at least the second wing can thereafter deflect. In another embodiment, a dog-house assembly is provided on a trim piece to mate with the apparatus. In still another embodiment, a method for forming the fasteners is provided. In yet another embodiment, a method to attach a trim piece to a vehicle is provided.
Patent CA-2468324-A1 (CA)
Inventor: GOVARI ASSAF
IPC: A61B5/06
Filed: 2004-05-25
Abstract: Apparatus is provided for tracking an object in a body of a patient in the presence of an interfering article. A set of one or more radiators are adapted to generate an energy field at a fundamental frequency in a vicinity of the object. A position sensor, fixed to the object, is adapted to generate a signal responsive to the energy field. A control unit has access to a database of one or more harmonic frequency patterns associated with one or more respective specific types of interfering articles. The control unit is adapted to (a) receive the signal, (b) detect a pattern of harmonic frequencies of the fundamental frequency present in the signal responsive to an interaction of the interfering article with the energy field, (c) compare the pattern to harmonic frequency patterns stored in the database, (d) identify the interfering article responsive to the comparison, (e) correct the signal responsive to the identification of the interfering article and a magnitude of one or more of the harmonic frequencies in the detected pattern, and (f) determine position coordinates of the object responsive to the corrected signal.
Patent CA-2472016-A1 (CA)
Title: Method and device for identifying substances capable of modulating adipicyte differentiation
Inventor: STAELS BART
IPC: C12Q1/68
Filed: 2003-01-17
Abstract: The invention concerns a method for identifying compounds capable of modulating adipocyte differentiation, which consists in contacting the compound to be tested with genetically modified pre-adipocyte cells overexpressing the <I>REV-ERB-ALPHA</I> receptor and measuring the adipocyte differentiation of said genetically modified cells with the adipocyte differentiation of same said genetically modified pre-adipocyte cells in the absence of said compound to be tested. The invention also concerns genetically modified pre-adipocyte cells overexpressing the <I>REV-ERB-ALPHA</I> receptor as well as the method for preparing said cells.
Patent CA-2472911-A1 (CA)
Title: Container with elastomeric lid spring
Inventor: BENZON IAN THOMAS
IPC: B65D43/24
Filed: 2004-07-06
Abstract: A container body with a lid hingedly joined thereto for movement about a pivot axis utilizing an elastomeric spring of generally ellipsoidal configuration extending transversely across the pivot axis and having opposed ends seated within the container body and lid, the spring folding centrally at the area of maximum thickness with the elastic deformation biasing the lid to its open position upon release of the closing force on the lid. The pivotal hinge assembly is enclosed by an integral transversely extending handle panel outward of the hinge assembly.
Patent CA-2473447-A1 (CA)
Inventor: VAN DER MEIJ PAULUS F C
IPC: A61P9/00
Filed: 2003-01-15
Abstract: The present invention relates to a compound of the general formula(I)wherein:  R1 is a selected from the group consisting of (C1-C6)alkoxy(C1-C6)alkyl which may be substituted by a (C1-C6)alkoxy, phenyl-(C1-C6)-alkyl and phenyloxy-(C1-C6)-alkyl wherein the phenylgroup may be substituted with (C1-C6)alkyl, (C1-C6)alkoxy or halogen, and naphtyl-(C1-C6)-alkyl,R2 and R3 are both independently hydrogen or halogen,R4 is a biolabile ester forming group,as a pharmaceutically acceptable metal salt, characterized in that the salt is selected from the group consisting of the lithium salt and bivalent metal ion salts such as magnesium, calcium and zinc salts. The invention further relates to a method for the preparation of the above salts, to a pharmaceutical composition comprising the salts of the invention, to the use of these salts in the treatment of hart disorders or hypertension, in the improvement of gastrointestinal blood flow or in the treatment and prophylaxis of cardiac damages induced by adriamycin and comparable anti-cancer drugs and to crystalline S-a-methylbenzylamine salts of the compounds of formula (I) that are useful as an intermediate in the production of the above mentioned salts.
Patent CA-2474113-A1 (CA)
Title: All-in-one toothbrush, toothpaste, plaque & tartar remover
Inventor: IBUSCA JOSE Y
IPC: A61C17/00
Filed: 2004-07-26
Abstract: Dentists and people use a scraper made of steel to remove plaque and tartar. Some use toothpaste and toothbrushes. in this invention, All-in-One Toothbrush, Toothpaste, Plaque & Tartar Remover, ToothCleaner/Whitener, not only a scraper but also toothpaste and toothbrush all in one. The handle (of the toothbrush scraper) is an emery board made of wood or plastic with the dimension of 11.5 centimeter in length, 1 centimeter in width, 0.2 centimeter in thickness, arched on both ends and covered with the "MagicChemical", or cloth fiber shaped-like and fits the forefinger and thumb, with ends covered with the "MagicChemical". It is either manually operated or electronically operated tooth brush's head with the bristles replaced with the "MagicChemical.    The "MagicChemical" is composed of adhesive and apricot shell, walnut shell, corn grits, peppercorn, or egg shell grounded in the size of the finest sand on earth, sodium monofluorophosphate, calcium carbonate, sorbitol or glycerine, precipitated silica, gum base, sodium benzoate, tetrapotassium pyrophosphate, tetra sodium pyrophosphatesodium lauryl sulphate, carbamide peroxide, sodium chlorite and water.   The user will push upward and downward in sliding motion using the tips of the emery board with the "MagicChemical". The user rubs the teeth in between the thumb and forefinger with the cloth fiber shaped-like as such on with the tips covered by "MagicChemical". The user will brush on the surface of teeth using the tip of the toothbrush with the "MagicChemical" on. All these with the intention of removing plaques, tartar, cleaning and/or whitening the teeth. The good thing about this invention is that it's disposability after one single use.
Patent CA-2474842-A1 (CA)
Title: Suture packaging
Inventor: KIRSCH DAVID
IPC: A61B17/06
Filed: 2004-07-16
Abstract: A package for surgical suture material includes a base member and a cover member, wherein the cover member is configured to be placed adjacent to the base member to form the package for the surgical suture material. The base member includes an outer wall extending from an outer circumference thereof. The outer wall has a predetermined height such that it engages the cover member when the cover member is placed adjacent the base member.  Partition structure extends from a bottom surface of the cover member and defines at least one suture retaining area.
Patent CA-2474959-A1 (CA)
Inventor: BELL IAN ALEXANDER WESTON
IPC: C10N10/04
Filed: 2004-07-16
Abstract: A multigrade crankcase lubricating oil composition comprising a mineral oil-based basestock of lubricating viscosity in a major amount and a non-hydrogenated olefin polymer in a minor amount. The lubricating oil composition also comprises a dispersant, a metal detergent, one or more other additives, and a viscosity modifier.
Patent CA-2475409-A1 (CA)
Title: Coronary tracking display
Inventor: EIGLER NEAL L
IPC: H04N5/325
Filed: 1991-11-12
Abstract: A method of displaying details of a coronary artery lesion in a cineangiogram, by adjusting each frame of the cineangiogram so that the lesion is continually displayed at a fixed location on a display.  The remaining cardiac anatomy appears to move, in background, past a stationary arterial segment, thus making the displayed arterial segment easier to identify and to examine by medical personnel. Cineangiographic image frames are digitized and processed by a processor (201) and the image frames are digitally shifted to place the arterial segment in substantially the same viewing location in each frame. Sequential image frames may be presented to the viewer as a stereoscopic pair, to produce pseudostereopsis. The arterial segment appears to the viewer in foreground, as if it was floating in front of the remaining cardiac anatomy.  Image frames may be further processed to aid examination by medical personnel. The processor may make quantitative measurements of the cineangiogram and may display results of those measurements to aid review of the cineangiogram. Frames may be averaged to reduce quantum noise and to blur any structure noise; frames may be compared with prior cineangiograms to increase clarity or contrast. Coordinate adjustments for a cineangiogram may help guide therapeutic procedures, or may help enhance other imaging procedures such as fluoroscopy.
Patent CA-2476147-A1 (CA)
Title: Motor enclosure for a vacuum cleaner
Inventor: DAVIS RONALD E
IPC: A47L9/00
Filed: 2004-07-30
Abstract: A motor enclosure for a vacuum cleaner includes a body having both a motor receiver for receiving a motor and a filter receiver for receiving a filter.
Patent CA-2477256-A1 (CA)
Title: Methods for aneurysm repair
Inventor: CARRISON HAROLD F
IPC: A61K38/00
Filed: 2003-03-06
Abstract: Disclosed here are methods of occluding a selected target site using rapidly expanding materials.