baber/WOPTO huggingface dataset:
Patent EP-3601539-A1 (EP)
Title: Méthodes de traitement de maladies néoplasiques
Inventor: ZHU ZHENGLUN
IPC: C12N15/00
Filed: 2018-03-28
Abstract: L'invention concerne une méthode de traitement d'un cancer, la méthode comprenant: l'apport d'un macrophage ou d'un monocyte modifié qui contient une séquence d'acide nucléique exogène codant pour un polypeptide Hom-1 ou un fragment de celui-ci qui contient le domaine de boîte homéotique Hom-1, le macrophage ou le monocyte modifié exprimant le polypeptide Hom-1 ou le fragment de celui-ci; et l'administration du macrophage ou monocyte modifié à un sujet atteint d'un cancer.
Patent EP-3487988-A1 (EP)
Inventor: CHIEN KENNETH R
IPC: G01N33/50
Filed: 2018-08-22
Abstract: The present invention provides NRP1 as a cell surface marker for isolating human cardiomyogenic ventricular progenitor cells (HVPs), in particular progenitor cells that preferentially differentiate into cardiac ventricular muscle cells. Additional HVP cell surface markers identified by single cell sequencing are also provided. The invention provides in vitro methods of the separation of NRP1+ ventricular progenitor cells, and the large scale expansion and propagation thereof. Large clonal populations of isolated NRP1+ ventricular progenitor cells are also provided. Methods of in vivo use of NRP1+ ventricular progenitor cells for cardiac repair or to improve cardiac function are also provided. Methods of using the NRP1+ ventricular progenitor cells for cardiac toxicity screening of test compounds are also provided.
Patent EP-3609397-A1 (EP)
Inventor: ANGLE MATTHEW R
IPC: G06F17/12
Filed: 2018-04-13
Abstract: A sensor circuit that is capable of sensing of neural action potentials is disclosed. The circuit can be designed to minimize power dissipation and total silicon area so that it can be incorporated into a massively parallel sensor array and ultimately implanted in the body (e.g. into the brain) in a safe manner. The circuit can also be designed to be tunable such that it can be optimized in silico prior to fabrication, and can be optimized through the use of controllable current sources after fabrication.
Patent EP-3610036-A1 (EP)
Inventor: TODD ALISON VELYIAN
IPC: C12Q1/68
Filed: 2018-04-11
Abstract: The present invention relates to compositions and methods for the detection of target molecules, and the amplification of detectable signals generated by detection assays. More specifically, the present invention relates to methods utilizing catalytic nucleic acid enzymes to generate and/or amplify a signal indicative of the presence of target molecules (e.g. nucleic acids and proteins), and compositions for use in the methods.
Patent EP-3697553-A1 (EP)
Title: Apparatus for coupling a coolant supply to a roll
Inventor: STAVENOW AXEL
IPC: B22D11/128
Filed: 2018-10-15
Abstract: The invention relates to an apparatus (1) for coupling a coolant supply and/or coolant discharge to a roll (2), in particular in a continuous casting installation, wherein the roll (2) comprises a journal (3), which is mounted rotatably in a bearing block (4) and has a lateral recess extending in the axial direction, and at least one roll cooling channel, through which a coolant can pass. The apparatus (1) comprises: at least one coolant channel (11, 12), which can be brought into fluidic connection with the roll cooling channel on the journal (3) side; and a sealing unit for sealing the fluidic connection between the coolant channel and the roll cooling channel, which sealing unit comprises an inner module and an outer module, the inner module comprising a hollow-cylindrical element (7), which can be inserted into the lateral recess in the journal (3). The invention is characterised in that the hollow-cylindrical element (7) does not comprise a flange on the outer side of the journal, as considered in the axial direction.
Patent EP-3618583-A1 (EP)
Inventor: KITAZUMI NOBORU
IPC: H01L23/12
Filed: 2018-04-23
Abstract: An electronic element mounting substrate includes a substrate in a quadrangular shape, including a first main surface and a second main surface opposite to the first main surface, and heat dissipators arrayed and embedded in the substrate, made of a carbon material, and including a third main surface located on the first main surface side in a thickness direction and a fourth main surface opposite to the third main surface. The heat dissipators have, in a plan perspective view, greater heat conduction in a direction perpendicular to a direction in which the heat dissipators are arrayed than heat conduction in the direction in which the heat dissipators are arrayed.
Patent EP-3692643-A1 (EP)
Inventor: FAXÉR SEBASTIAN
IPC: H04L5/00
Filed: 2018-10-02
Abstract: A method of identifying reference signal resources to be used in a transmission by a wireless device is disclosed. The method comprises a wireless device receiving signaling configuring the wireless device with a plurality of reference signal resource groups, each group comprising a plurality of reference signal resources. The wireless device subsequently receives an indication, in a control channel, of a selection of reference signal resources to be used. Each of the plurality of reference signal resources to be used is selected from a different one of the plurality of reference signal resource groups such that reference signal resources belonging to the same reference signal resource group are not selected for simultaneous use. A reference signal is then transmitted to a network node in the network using the indicated selection of reference signal resources.
Patent EP-3631815-A1 (EP)
Title: Very simplified boiling water reactors for commercial electricity generation
Inventor: HUNT BRIAN S
IPC: F16K3/314
Filed: 2018-04-19
Abstract: Nuclear reactors have very few systems for significantly reduced failure possibilities. Nuclear reactors may be boiling water reactors with natural circulation-enabling heights and smaller, flexible energy outputs in the 0-350 megawatt-electric range. Reactors are fully surrounded by an impermeable, high-pressure containment. No coolant pools, heat sinks, active pumps, or other emergency fluid sources may be present inside containment; emergency cooling, like isolation condenser systems, are outside containment. Isolation valves integral with the reactor pressure vessel provide working and emergency fluid through containment to the reactor. Isolation valves are one-piece, welded, or otherwise integral with reactors and fluid conduits having ASME-compliance to eliminate risk of shear failure. Containment may be completely underground and seismically insulated to minimize footprint and above-ground target area.
Patent EP-3713880-A1 (EP)
Inventor: BENZING CHRISTIAN P
IPC: C02F1/50
Filed: 2018-10-26
Abstract: Die Erfindung betrifft einen bioaktiven Filter zur Desinfektion von Flüssigkeiten, insbesondere Wasser oder wässrigen Lösungen in Behältnissen. Ein für die Filtereffizienz vorteilhafter Aufbau wird dadurch erhalten, dass ein kugelförmiger oder ovaler Filterkörper (1) gebildet ist, der mit Edelmetallen beschichtet ist.
Patent EP-3694607-A1 (EP)
Inventor: SONG BRIAN XIAOQING
IPC: A61K8/44
Filed: 2018-10-10
Abstract: A compact, stable shampoo composition containing a cationic polymer and from about 20% to about 40%, by weight, of a surfactant system. The shampoo composition is substantially free of sulfate-based surfactants. The surfactant system contains acyl glutamate and one or more co- surfactants. The weight ratio of acyl glutamate to total surfactant can be less than 0.55.
Patent EP-3726956-A1 (EP)
Inventor: VEER ANDREW MARK
IPC: A01D43/00
Filed: 2018-10-11
Abstract: There is disclosed a tensioning bar assembly (111) for a tensioning assembly (101) of a drive system (60) of an agricultural machine, having: A longitudinal bar (102) having a longitudinal axis (102x), a top end (102t) and a bottom end (102b) and a threaded portion (102a) over at least a portion of the bar; An attachment device (103) coupled to the top end of the longitudinal bar for attaching the top end of the bar to a tensioning arm (41); A compression spring (4s) having first (6b) and second (6t) ends, said spring located around a portion of the longitudinal bar; A first spring retainer (4b) for engaging with and retaining the first end (6b) of the spring; A first locking nut (5a) for fitting to the threaded portion (102a) of the bar and for retaining the first spring retainer longitudinally in place relative to the bar; wherein the longitudinal bar is rotationally freely coupled to the attachment device (103) such as to permit free axial rotation of the bar about the longitudinal axis (102x) relative to the attachment device, and there is further provided an engagement head (102h, 302h) attached to and located at or proximate the bottom end (102b) of the longitudinal bar (102), said engagement head for engagement with a tool.
Patent EP-3622707-A1 (EP)
Inventor: DAMBERG GERWIN
IPC: H04N5/74
Filed: 2018-05-11
Abstract: A hybrid projector architecture combines steered light with unsteered light. In some embodiments the steered light is narrowband light and the unsteered light is broadband light. Splitting between the steered and unsteered light may be determined based on luminance level. For example, the unsteered light may contribute a large proportion of the light for luminance levels up to a threshold. The steered light may contribute an increasing proportion of the light as luminance values rise above the threshold.
Patent EP-3685075-A1 (EP)
Inventor: DEL MASTRO ALESSIO
IPC: F16H61/4035
Filed: 2018-09-20
Abstract: The supply unit (10) comprises a casing (11) containing a pump device (14) and having a motion input (Ml) for mechanically driving the pump device, and a first and a second hydraulic power port (HP1, HP2). The casing contains a hydraulic valve device (16) for selective connection between the pump device (14) and the hydraulic power ports (HP1, HP2). The unit is configured for connection to control means (20) of the hydraulic valve device (16) and for adoption of a resting state in which the first and second hydraulic power ports (HP1, HP2) are subject to a common resting pressure and an activated state in which the first and second hydraulic power ports are respectively subject to a high pressure and a low pressure of the pump device.
Patent EP-3713956-A1 (EP)
Inventor: LOESCHE CHRISTIAN
IPC: A61P17/10
Filed: 2018-11-19
Abstract: La présente invention concerne des méthodes de traitement de l'hidradénite suppurée (HS) à l'aide d'antagonistes d'IL-17, par exemple, le secukinumab. L'invention concerne également des antagonistes d'IL-17, par exemple, des anticorps dirigés contre IL-17, tels que le secukinumab, pour traiter des patients souffrant de HS, ainsi que des médicaments, des régimes posologiques, des formulations pharmaceutiques, des formes posologiques et des kits destinés à être utilisés dans les utilisations et les procédés selon l'invention.
Patent EP-3467254-A1 (EP)
Inventor: LU WENJIA
IPC: E21C25/06
Filed: 2018-08-08
Abstract: A vertical lifting type comprehensive drum coal-mining machine without a rocker arm comprises a central control box, left and right cutting and lifting reduction gear boxes, left and right guide rail fixing box bodies, left and right traction reduction gear boxes, and left and right traveling gear boxes. The left and right cutting and lifting reduction gear boxes are provided with slideways in fit with lifting guide rails of the left and right guide rail fixing box bodies. Lifting cylinders drive the left and right cutting and lifting reduction gear boxes to make lifting motion. A cutting gear reduction mechanism adopts two-stage fixed-axle gear transmission and two-stage planetary gear transmission, is free from multiple idler pulley groups and has simple transmission chain. The fit between the lifting guide rails and the slideways enables the entire machine to be compact in structure, and the reliability and stability of operation are improved.
Patent EP-3645411-A1 (EP)
Inventor: GOODRICH DAVID P
IPC: B65D65/02
Filed: 2018-06-26
Abstract: An extensible slit sheet paper product is produced having an expandable slit pattern that forms open cells upon expansion of the paper product. The paper product is an extensible paper having an extensibility in the range from 1-9% in the machine direction and 1-5% in the cross direction. The expansion produces an array of hexagonal cells. The expanded extensible paper can be used to wrap an object for shipping by wrapping and cushioning the object in the expanded slit sheet material. The extensible, expandable slit sheet paper can be wrapped around itself to produce a void fill product.
Patent EP-3728558-A1 (EP)
Inventor: RODRÍGUEZ PASCUAL FERNANDO
IPC: C07K14/78
Filed: 2018-12-18
Abstract: The present invention relates to an extracellular matrix comprising ECM producer cells, a lysyloxidase (LOX), and bone morphogenetic protein-1 (BMP1), and its use for regulating the differentiation of mesenchymal stem cells and increasing the synthesis and/or deposit of collagen in an extracellular matrix. The present invention also relates to a method for obtaining said extracellular matrix comprising incubating cells in the presence of a composition comprising a lysyl oxidase, or a fragment thereof, and bone morphogenetic protein-1, or a fragment thereof.
Patent EP-3735676-A1 (EP)
Inventor: DWIVEDI SHEKHAR
IPC: G06T11/00
Filed: 2018-12-24
Abstract: La présente invention concerne un support lisible par ordinateur non transitoire qui stocke des instructions lisibles et exécutables par au moins un processeur électronique (20) afin d'effectuer un procédé de reconstruction d'image (100). Le procédé comprend les étapes suivantes : réalisation d'une reconstruction d'image itérative de données d'imagerie acquises à l'aide d'un dispositif d'acquisition d'image (12); sélection d'une image de mise à jour à partir d'une pluralité d'images de mise à jour produites par la reconstruction d'image itérative; traitement de l'image de mise à jour sélectionnée pour générer une carte d'artéfact de points chauds; et suppression des points chauds identifiés par la carte d'artéfact de points chauds générée dans une sortie d'image reconstruite par la reconstruction d'image itérative.
Patent EP-3635505-A1 (EP)
Inventor: TAN YONGXI
IPC: G06F/
Filed: 2018-07-05
Abstract: A neural network is trained using deep reinforcement learning (DRL) techniques for adjusting cell parameters of a wireless network by generating a plurality of experience tuples, and updating the neural network based on the generated experience tuples. The trained neural network may be used to select actions to adjust the cell parameters. Each experience tuple includes a cell identifier, a first state, a second state, an action applied to the cell that moves the cell from the first state to the second state, a local reward, and a global reward. The neural network is updated based on whether or not each action is acceptable, which is determined based on the global reward and the local reward associated with each action.
Patent EP-3704789-A1 (EP)
Title: Frequency converters with at least one booster capacitor
Inventor: LETINA DRAZEN
IPC: H02M3/137
Filed: 2018-10-24
Abstract: Owing to the use of "booster" capacitor at the output of the frequency converter, additional currents flow through the electric motor, so it is possible to load an electric motor depending on the performance of the frequency converter, as shown in Figures 1 to 5, with a maximum power of 95%, respectively according to configurations shown in pictures of 8 to 10 with a maximum power of 90%. Therefore, with aim to solve the above said problem, the present patent reveals new type of frequency converters having the "booster" capacitor which is at voltage that is higher than that of the grid voltage.The present invention proposes two types of frequency converters: a) Converters with input DC link b) Converters which don't have an input DC link, but are powered from the grid via the motor winding (without rectifying diodes).
Patent EP-3657204-A1 (EP)
Inventor: SATO MAKOTO
IPC: G01C3/06
Filed: 2018-07-10
Abstract: An optical device (1) comprises: a line sensor (9) having a plurality of light reception elements that receive incident light including reflection light resulting from laser light having been emitted from a light source (2) and reflected by an object (100), and including ambient light; a diffraction grating (7) that guides the incident light to the plurality of light reception elements by diffracting the incident light to a direction depending on the wavelength; and a control unit (10) that detects the reflection light on the basis of the light reception amounts of the light reception elements. The diffraction grating (7) is configured to guide, to one of the plurality of light reception elements, a wavelength within a predetermined range that includes the wavelength of the laser light emitted from the light source (2).
Patent EP-3660970-A1 (EP)
Title: Electrolyte composition, electrolyte film, and cell
Inventor: KANAMURA KIYOSHI
IPC: H01M10/052
Filed: 2018-07-24
Abstract: An electrolyte composition characterized in comprising an electrolyte powder, a binder, and an ion-conductive material; the electrolyte powder being an oxide-based ceramic electrolyte powder; the binder being a polymer compound that is stable with respect to metal ions; the ion-conductive material being a solvated ion-conductive material or an ion-conductive solution having a metal ion-based compound. An electrolyte film characterized in being provided with an electrolyte powder and a composite material in which a binder and an ion-conductive material are made into a composite.
Patent EP-3628122-A1 (EP)
Inventor: HUANG CICHANG
IPC: H04N5/268
Filed: 2018-02-13
Abstract: A system may comprise at least one signal input circuit configured to receive target input signals from at least one sensor device; at least one signal processing unit. Each of the at least one signal processing unit may include at least one signal output circuit configured to output signals to a first electronic connection; and at least one signal extraction circuit configured to obtain a reverse control signal from the first electronic connection; and at least one signal superimposing circuit configured to generate superimposed reverse control signals by superimposing the first reverse control signal with other electronic signals, and output the superimposed reverse control signal to the signal input circuit.
Patent EP-3653013-A1 (EP)
Title: Method and apparatus for handling a beam failure recovery in wireless communication system
Inventor: AMURU SAIDHIRAJ
IPC: H04W74/00
Filed: 2018-08-10
Abstract: The present disclosure relates to a pre-5 th -Generation (5G) or 5G communication system to be provided for supporting higher data rates beyond 4 th -Generation (4G) communication system such as long term evolution (LTE). A terminal in a wireless communication system is provided. The terminal includes a transceiver, and at least one processor configured to receive, from a base station (BS), a beam failure recovery configuration comprising at least one reference signal for identifying a candidate beam for the beam failure recovery and associated random access (RA) parameters, identify the candidate beam for the beam failure recovery using the at least one reference signal, and perform a physical random access channel (PRACH) using the at least one reference signal and the associated RA parameters on the candidate beam for the beam failure recovery.
Patent EP-3672615-A1 (EP)
Inventor: LOW PHILIP STEWART
IPC: A61K38/08
Filed: 2018-08-21
Abstract: The present disclosure relates to compositions and methods of carbonic anhydrase IX inhibitors. The present disclosure also relates to targeting conjugates of carbonic anhydrase IX inhibitors. The present disclosure also relates to the use of targeting conjugates of carbonic anhydrase IX inhibitors in methods of treating disease and for imaging of disease.
Patent EP-3675884-A1 (EP)
Inventor: GALLO RICHARD L
IPC: A61K35/741
Filed: 2018-08-31
Abstract: The invention provides a purified polypeptide which inhibits (i) protease production and/or activity of keratinocytes, (ii) inhibits IL-6 production and/or activity of keratinocytes, (iii) inhibits production of phenol soluble modulin alpha 3 from Staphylococcus aureus and/or (iv) inhibits agr production and/or activity by S. aureus. Further provided is a topical formulation comprising the polypeptide. Provided is a recombinant microorganism comprising a vector or polynucleotide encoding the polypeptide. Further provided is a probiotic composition comprising the recombinant microorganism. The invention also provides kits and articles of manufacture comprising the polypeptide and/or the recombinant microorganism.
Patent EP-3675802-A1 (EP)
Inventor: ZALTSMAN NATHAN
IPC: A61K6/896
Filed: 2018-08-30
Abstract: This invention relates to compositions and medical devices comprising anti-microbial active particles, for inhibiting microbial growth. This invention further provides methods of making such compositions and medical devices.
Patent EP-3683252-A1 (EP)
Inventor: KATORI AKANE
IPC: C08G65/32
Filed: 2018-08-28
Abstract: A compound is provided which is effectively adsorbed to a substrate surface, such as an immune reaction vessel, has extremely high protein adsorption inhibitory effect that inhibits non-specific adsorption of protein or the like, and has excellent washability to retain the inhibitory effect before and after washing operation of the substrate. Also provided are a protein adsorption inhibitor using the compound, a phosphorylcholine-modified substrate, and a method for inhibiting protein adsorption. The compound is a phosphorylcholine group-containing polyethylene glycol derivative represented by formula (1). The method for inhibiting protein adsorption of the present invention includes the step of forming an adsorbed layer of the derivative on a substrate surface.
Patent EP-3643336-A1 (EP)
Inventor: KUROSAKI YASUO
IPC: A61M25/10
Filed: 2018-09-21
Abstract: There is provided a method and apparatus for forming a drug coating layer capable of preventing breakage of elongated drug crystals on a surface of a balloon and maintaining the drug crystals in an appropriate shape in order to act on a living body. A method for forming a drug coating layer (40) in which a plurality of elongated bodies (42) which are crystals of a water-insoluble drug and each have a long axis are formed on a surface of a balloon (30), and the method includes a step of supplying a coating solution which contains the water-insoluble drug, a water-soluble additive, an organic solvent, and water to the surface of the balloon (30) and evaporating the organic solvent and the water to form an additive layer (41) containing the water-soluble additive and a protruding crystal (48) having a tip end protruding from the additive layer (41), a step of cutting out a surplus portion (49) protruding from the additive layer (41) of the protruding crystal (48) from a part surrounded by the additive layer (41) and forming the part surrounded by the additive layer (41) as the elongated body (42), and a step of removing the cut-out surplus portion (49) from the drug coating layer (40) .