baber/WOPTO huggingface dataset:
Patent CR-20120418-A (CR)
Title: Inhibidores de virus flaviviridae
Inventor: CANALES EDA
IPC: A61K31/381
Filed: 2012-08-10
Abstract: Se proporcionan compuestos de Fórmula I y sales y ésteres farmacéuticamente aceptables de los mismos. Los compuestos, composiciones, y métodos que se proporcionan son útiles para el tratamiento de infecciones del virus Flaviviridae, particularmente infecciones de hepatitis C.
Patent CR-20170230-A (CR)
Title: Anticuerpos anti-cd79b y métodos de uso
Inventor: SUN LIPING L ;
IPC: C07K16/28
Filed: 2015-12-04
Abstract: La invención proporciona anticuerpos anti¿CD79b y métodos para su uso.
Patent CR-20190014-A (CR)
Title: Derivados etinilo
Inventor: BIEMANS BARBARA;
IPC: C07D487/10
Filed: 2017-07-12
Abstract: La presente invención se refiere a compuestos de fórmulas IA y IB o a una sal o sal de adición de ácido farmacéuticamente aceptable, a una mezcla racémica o a su enantiómero y/o isómero óptico y/o estereoisómero correspondiente de los mismos. Los compuestos pueden utilizarse en el tratamiento de la enfermedad de Parkinson, la ansiedad, la emesis, el trastorno obsesivo-compulsivo, el autismo, la neuroprotección, el cáncer, la depresión y la diabetes de tipo 2.
Patent EC-SP045059-A (EC)
Title: Sintesis de analogos de ciclosporina
IPC: A61P7/04
Filed: 2004-04-14
Abstract: El invento está dirigido hacia mezclas isómeras de análogos de ciclosporina que son estructuralmente similares a la ciclosporina A. Las mezclas poseen eficacia afianzada y reducida toxicidad con respecto a los isómeros individuales y por sobre ciclosporinas que ocurren naturalmente y derivados de ciclosporina actualmente conocidos. Las presentaciones del presente invento están dirigidas hacia cis y trans-isómeros de análogos de ciclosporina A que se han denominado ISATx247, y sus derivados. Las mezclas de isómeros ISATx247 exhiben una combinación de mayor potencia y menor toxicidad con respecto a ciclosporinas que ocurren naturalmente y que se conocen actualmente. Los isómeros ISATx247 y derivados alcalinados, arilados y deuterados se sintetizan mediante vías estéreo-selectivas en las que las condiciones particulares de una reacción determinan el grado de estéreo-selectividad. Las vías estéreo-selectivas podrán utilizar una reacción Wittig, o un reactivo órgano-metálico que comprende elementos inorgánicos tales como boro, silicón, titanio, y litio. La tasa de isómeros en una mezcla podrá variar de entre alrededor de 10 a 90 por ciento según peso del isómero (E) hasta alrededor de 90 a 10 por ciento según peso del isómero (Z), de acuerdo al peso total de la mezcla.
Patent EC-SP961904-A (EC)
Title: Etiquetas elasticas de aplicación para contenedores cilindricos
Inventor: BRIGHT LYN E
IPC: B65B53/00
Filed: 1996-10-23
Abstract: Un metodo para aplicar a artículos tales como contenedores, segmentos de material de hoja, tales como etiquetas, que son elásticos. Cada segmento tiene un extremo delantero y un extremo trasero que no están conectados uno al otro formar una funda excepto por adhesivo. Tal segmento es aplicado a los artículos en una condición tensionada tal que este se encogerá para conformarse a la superficie del artículo cuando, por ejemplo, el artículo se encoge. También los artículos resultantes son novedosos y se reivindican.
Patent EC-SP961940-A (EC)
Title: Sulfoxilatos aldehidico alquino como nematicidas insecticidas y fungicidas
Inventor: MILLER PERRASSE JORGE
IPC: C05G3/60
Filed: 1996-11-18
Abstract: Ninguna composición no fitotóxica fungicida, insecticida, nematicida u ovicida, comprende una efectiva cantidad de sulfoxilato aldehídico alquino y un transportador inerte agronómicamente aceptable, son útiles para combatir sistemáticamente fungus, insectos, nematodos y larvas con las cuales las plantas estan infestadas. También son utiles para proteger los cortes de plantas (para ser enraizados) de las bacterias, virus y / o fungus por la inmersión de dichos cortes en una solución acuosa comprendido una cantidad efectiva de sulfoxilato aldehïdico alquino. Los cortes de las plantas enraizadasson protegidas en forma similar, aplicando una composición parecida a los cortes enraizados. Si los tallos de flores cortados son sumergidos en una solución de sulfoxilato aldehídico alquino, duran más que las flores cortadas no tratadas. Un objetivo de esta invención es proporcionar un sistema fungicida, insecticida, nematicida y ovicida más efectivo para el tratamiento de plantas infestadas.Otro objetivo de esta invención, es proporcionar una composición para mejorar el desarrollo de la planta para proteger los cortes de las mismas para enraizar y cortes de plantas enraizadas de las bacterias, virus y/o fungus y para prolongar la viabilidad de los cortes de las flores.
Patent EC-SP993178-A (EC)
Title: Terapia combinatoria con ribarvirina -interferon alfa para erradicar el hcv - rna detectable en aquellos pacientes que presentan infeccion por hepatitis c cronica
Inventor: SAKSENA ANIL K
IPC: C07D405/04
Filed: 1999-10-14
Abstract: Un método para tratar un paciente que padece de una infección por hepatitis C crónica, a los efectos de erradicar el HCV-RNA detectable, que comprende una terapia combinatoria, la cual emplea una cantidad terapéuticamente efectiva de un derivado de ribavirina de la fórmula I y una cantidad terapéuticamente efectiva de interferón alfa, durante un lapso que varía entre 20 y 80 semanas.
Patent FI-19992514-A (FI)
Inventor: KIRJAVAINEN KARI
IPC: H04R19/01
Filed: 1999-11-25
Abstract: An electromechanic film intended for transforming electric energy into mechanical energy and transforming mechanical energy into electric energy. The film (1) is dielectric and formed of cells (3), the ratio of the height and width of which cells is between 3:1 and 1:3. By joining two such films together and controlling them in such a way that in the first film (1) the electric field strength decreases and in the second film (1) the electric field strength increases, a bending acoustic element is provided.
Patent FI-20000519-A (FI)
Inventor: EEROLA VILLE ANTERO
IPC: H04B1/707
Filed: 2000-03-07
Abstract: The present invention relates to a device for generating at least one code phase (Ce, Cp, Ci) the device comprising a shift register (702) comprising N outputs and to which a code sequence (Cin) to be phased is applied, and at least one logic branch (722, 723, 724) controlled by at least one combination control signal on the basis of which the logic branch combines the code phase from i outputs of the shift register (702). N is an integer greater than 2 and i is an integer between 2 and N. Said at least one logic branch preferably comprises i two-input selectors (901 to 909, 911 to 919, 921 to 929), to the first input of each of which is connected one input of the shift register (702) and to the second input is connected one combination control signal (ec0 to ec8, pc0 to pc8, lc0 to lc8), and an i-input combiner (910, 920, 930), to whose outputs are connected the outputs of said i selectors and from whose output said code phase is obtained.
Patent FI-20021626-A (FI)
Inventor: CHIEN DAVID Y
IPC: C07K16/00
Filed: 2002-09-11
Abstract: We have discovered epitopes of the HCV viral proteins which are immunoreactive with immune serum. The epitopes are useful in immunodiagnostic assays and as immunogens.
Patent FI-20030581-A (FI)
Inventor: LU WENTAO
IPC: B31B50/50
Filed: 2003-04-16
Abstract: The invention is related to hinge-lid boxes or containers for cigarettes, cigars, pastilles, sweets and other goods. The invention relates to a method for the manufacture of said hinge-lid boxes, particularly to a method for attaching of the collar to the packet portion. The method comprises steps wherein and the collar is glued to the packet portion of the hinge-lid box by applying the glue as horizontal uniform glue lines on the blank of the collar and/or horizontally on the respective area of the blank of the box part, which the collar will be attached to and the number of horizontal glue lines is at least two.
Patent FR-1210099-A (FR)
IPC: B60P1/02
Filed: 1958-08-29
Granted: 1960-03-07
Abstract: 908,520. Mine shuttle cars. JOY MANUFACTURING CO. May 20, 1959 [June 9, 1958], No. 17098/59. Addition to 894,065. Class 78 (4). [Also in Group XXXII] The mine haulage vehicle claimed in the parent Specification is modified by the provision of means, associated with the vehicle wheels suspension device and operable by remote control, for elevating and lowering the end portion of the vehicle body relative to the wheels at at least one end of the vehicle. As shown in Fig. 3, the steering-wheels 9 at each end of the vehicle are supported on links 17, 18, which are pivotally mounted at 24, 22 respectively, on the body 1. Arms 33 integral with links 17, are connected by a roller chain 31, and a doubleacting hydraulic ram 36, 37, slidable in guides 34 and forming a link of the chain 31, is provided, which, on extension under the action of control means 41, Fig. 2, lowers the body section 1 with respect to the wheels 9. In a modification, Fig. 6 (not shown), the hydraulic ram 36, 37 is replaced by a pair of rams pivoted between the links 18 and links pivoted to the body. In further modifications, Figs. 9, 12 (not shown), hydraulic rams are pivoted between a transverse axle, pivoted to the body, and wheel supports, pivoted to the axle. The vehicle is also provided with wheels 10 driven by motors 11.
Patent FR-1602706-A (FR)
Title: Ski comprising epoxy or polyester encased - metal profile and spacer blocks
IPC: A63C5/12
Filed: 1968-10-08
Granted: 1971-01-18
Abstract: Composite ski construction comprises a light alloy metal profile surrounded by spacer blocks of wood, hollow box structures or (foamed) plastic and encased in a thermosetting resin skin (polyester or epoxy resin based), with boot clamps; sole strips etc. The ski sole is concave. More reproducible than timber, easily adapted to optimise the size, weight, balance and stiffness.
Patent FR-1604687-A (FR)
Title: Insecticidal oil-in-water emulsions - with mineral silicate additives and reduced phytotoxicity
IPC: A01N25/04
Filed: 1968-12-31
Granted: 1972-01-03
Abstract: Acaricidal and insecticidal compsns. with an emulsified mineral oil base contg. reduced amts. of a non-ionic emulsifiers and mineral silicates as emulsification additives. Suitable silicates are montmorillonites, bentonites and attapulgites opt. modified by ion-exchange with organic bases, which have plasticity index of >25, and which form gels with water. Prefd. silicate content is 1:5-3% w/w. Emulsifier content may be reduced to 0.13%.
Patent GB-1047337-A (GB)
IPC: H01J29/82
Abstract: 1,047,337. Electron lenses. ENGLISH ELECTRIC VALVE CO. Ltd. May 21, 1964 [Aug. 14, 19631, No. 32121/63. Heading H1D. An electrostatic lens with overlapping tubular electrodes 7, 8, 9 has the electrode 7 of telescopic construction, as shown with an insert 14, so that final adjustment of the spacing b may be made after the electrodes have been mounted in position by the wires 12 fused in the support rods 13. The adjustment is made by mounting the electrode assembly on a jig with the insert abutting a spacing sleeve and gripped internally by expanding a rubber collar. The assembly is then adjusted so that the anode end of electrode 8 abuts against a spacing block with the spacing sleeve in contact between this block and the insert. The electrode 9 may be a coating on the envelope. The invention may be applied to an alternative form of lens in which the outer electrodes are of the same diameter.
Patent GB-1052330-A (GB)
IPC: B23D33/02
Abstract: 1,052,330. Shearing. LINDEMANN MASCHINENFABRIK G.m.b.H. Oct. 28, 1965 [Nov. 18. 1964], No. 45673/65. Heading B3W. A shear has a fixed cutter 2, a movable cutter 4, a hold-down 6 and a ram 8 which advances a work-piece 15 along the work-table 7. An auxiliary work-support table 10 is provided and is connected to the movable cutter carrier 3 by side-arms 11. When a short workpiece is advanced by the ram 8 the auxiliary worksupport table 13 prevents tipping of the workpiece as the ram 8 is withdrawn prior to the descent of the hold-down 6.
Patent GB-1052830-A (GB)
IPC: C21D1/84
Abstract: 1,052,830. Endless conveyers. DAVY & UNITED ENGINEERING CO. Ltd. Nov. 25, 1965 [Nov. 27, 1964; May 6, 1965], Nos. 48208/64 and 19193/65. Heading B8A. [Also in Division C7] Overlapping turns of wire are transported through a fluidized bed for cooling by means of a conveyer including endless chains 28, the pivotal links of which circulate on rails 21, 25 and upon which are mounted a series of brackets 34. To these brackets are attached horizontal plates 36 extending through slits 37 in the sides of the fluidized bed vessel 12, these plates having in turn secured to them depending brackets 41 upon the bases of which is mounted the conveying surface. The latter is formed of a series of transverse tubes 42 carrying bars 43, the upper edges of which are serrated, while further bars 45 are secured between the outer bars 43 and the brackets 41.
Patent GB-1143625-A (GB)
IPC: F25B9/04
Abstract: 1,143,625. Refrigerating. SOC. ANON. DES USINES CHAUSSON. 3 May, 1966 [4 May, 1965], No. 19544/66. Heading F4H. A vortex tube assembly includes a rectifying element 20 in the hot gas outlet pipe 19 for modifying the flow characteristics of the hot gas. The form of the element is shown in Fig. 5. Compressed gas is fed through a line 5 to an annular space 4 formed between two members 2, 3 and then passed tangentially into the vortex chamber 17, the cold outlet 13 of which communicates with a diverging passage 18 in member 3. The cold air then passes through a easing 32, which is lined with sound-absorbing material and includes a sound-absorbing baffle 34, into an outlet tube 35. Untreated air may be supplied to the latter through a by-pass line 37. The outlet end of the hot gas pipe 19 is disposed in a easing 26 having a sound-absorbing lining and an outlet 30, and is provided with an axially movable valve assembly 22, 23, 24.
Patent GB-1225211-A (GB)
IPC: A21C11/16
Filed: 1969-04-16
Abstract: 1,225,211. Wet separating. CARPCO RESEARCH & ENG. Inc. 16 April, 1969 [25 Nov., 1968], No. 19471/69. Heading B2H. A trough concentrator is provided with lateral guides 26 which initially converge the flow of slurry to stratify the particulate material, and then diverge the flow to spread the strata, the lower stratum then being removed through a slot 42. The process may be repeated in further sections 14, 15. The guides are secured to the side walls by nuts 25 and bolts 19 and can be adjusted in the direction of flow. Slurry is supplied from spaced outlets (62) (Fig. 4, not shown) in a hopper 50, and smooth flow is induced by passage through a horizontal slit in a baffle 63. The slot 42 may be formed in a removable plate (Fig. 5, not shown). The internal surfaces of the concentrator may be of plastics material.
Patent GB-1225611-A (GB)
IPC: H02H3/04
Filed: 1967-09-15
Abstract: 1,225,611. Protective arrangements. EXPERT INDUSTRIAL CONTROLS Ltd. 6 Sept., 1968 [15 Sept., 1967], No. 42078/67. Heading H2K. A solenoid 10, which is mounted in a casing with an armature, is protected by a thermal switch 13 mounted within the casing so as to be heated by the solenoid 10 and having its contacts connected in series with the solenoid. A lamp 14 is connected so as to be lit when the solenoid is energized and a further lamp 15 is connected across the switch 13 so as to be lit when the switch opens due to overloading of the solenoid 10. The lamp 14 may be connected across the solenoid 10 as shown, or to a winding wound on the solenoid 10, Fig. 2 (not shown), or to a tapping on the solenoid 10, Fig. 3 (not shown).
Patent GB-1230958-A (GB)
IPC: C07D271/113
Filed: 1968-10-01
Abstract: 1,230,958. 4-Fluorophenylsalicy acid derivatives. MERCK & CO. Inc. 1 Oct., 1968 [6 Oct., 1967], No. 36309/70. Divided out of 1,229,669. Heading C2C. Novel compounds of formula in which X is 5-tetrazolyl or 5-(2-hydroxy-1,3,4- oxadiazoyl) and Z is H, C 1-6  alkanoyl, N-(C 1-5 - alkyl)-carbamoyl, C 1-6  haloalkanoyl, C 2-6  alkoxycarbonyl, aryloxycarbonyl, aroyl, benzoyl substituted by halo, C 1-5  alkyl or C 1-5  alkoxy, N,N-di-(C 1-5 -alkyl) carbamoyl alkyl, or a carbohydrate or sugar residue such as N- acetylglucosaminido or N-acetylgalactoseaminido are prepared by reaction of (a) the intermediate, wherein X is -C#N with sodium azide or (b) the intermediate, wherein X is a hydrazide residue with phosgene respectively. Benzoyl - 5 - (4<SP>1</SP> - fluorophenyl) - benzonitrile is prepared by heating 2-hydroxy-5-(4<SP>1</SP>-fluorophenyl)-benzamide and benzylidyne chloride. Starting materials are prepared as in the parent Specification. Pharmaceutical compositions in conventional forms for oral administration and having antiinflammatory, anti-pyretic and analgesic activity and effective in prevention of oedema and granuloma tissue formation comprise an above novel compound and an inert diluent carrier or coating.
Patent GB-1231357-A (GB)
IPC: B05C19/02
Filed: 1969-10-30
Abstract: 1,231,357. Pneumatic conveying. CONTINENTAL CAN CO. Inc. 30 Oct., 1969 [4 Nov., 1968], No. 53294/69. Heading B8A. A device for conveying powder 6a from a chamber 6 via a feed tube 16 and exit conduit 18, comprises an aspirator tube 15 in the chamber and having its nozzle adjacent the inner end of the feed tube 16, the aspirator being supplied with pressurized gaseous fluid whereby powder is drawn from the chamber into the feed tube for discharge. The aspirator tube 15 is axially movable by a pneumatic ram 22 for engagement with the feed tube 16 when the feed tube is to be purged with gas. The chamber 6, which is vibrated, includes a porous bed 13 through which gas is supplied to fluidize the powder, further gas being supplied above the powder level. The upper end of the feed tube 16 may be provided with contoured apertures through which the fluidizing gas is drawn from the chamber with the discharging powder. The level of the powder in the chamber is controlled through a level-sensing device 12 which actuates in sequence, valves of an airlock device in a powder supply line between the chamber and a storage container.
Patent GB-1231742-A (GB)
IPC: B01F7/00
Filed: 1969-07-17
Abstract: 1,231,742. Mixing apparatus. NAUTAMIX PATENT A.G. 17 July, 1969 [18 July, 1968], No. 36162/69. Heading B1C. Mixing appartus comprises a vessel 1 provided with stirring members 8, 38 each of which is rotatable about its own axis and about the axis of symmetry of the vessel, the upper end of member 8 in addition being rotatable about the axis of shaft 19 so as to oscillate between the walls and the axis of symmetry of the vessel. The stirring members may be in the form of screws. Electric motor 26 is arranged to rotate the stirring members through appropriate gearing about the axis of symmetry of the vessel, as well as rotate member 38 about its own axis and oscillate the upper end of member 8 between the walls and axis of symmetry of the vessel. Shaft 9 is arranged to rotate member 8 about its own axis via coupling 11, 12. In a modification, the upper end of member 8 may be reciprocated along an arm of support 22. Reference has been directed by the Comptroller to Specification 1,041,619.
Patent GB-1231966-A (GB)
IPC: C07D305/08
Filed: 1969-10-13
Abstract: 1,231,966. Fluorooxetanes. VYSOKA SKOLA CHEMICKO - TECHNOLOGICKA. 13 Oct., 1969 [21 Oct., 1968], No. 50215/69. Heading C2C. Fluorooxetanes of formula in which R<SP>1</SP> and R<SP>2</SP> are hydrogen or alkyl groups are prepared by heating alkanols of formula R<SP>1</SP>R<SP>2</SP>C(OH)CF 2 CHClF in an alkaline medium. Examples are given of the preparation of 2 - methyl - 3,3,4 - trifluorooxetane and 2,2-dimethyl-3,3,4-trifluorooxetane.
Patent GB-1233582-A (GB)
IPC: C25D11/04
Filed: 1968-07-05
Abstract: 1,233,582. Anodizing. REYNOLDS METALS CO. July 5, 1968 [July 20, 1967], No.32318/68. Heading C7B. An anodizable metal e.g. Al or its alloy is anodized by passing an electric current preferably D.C. between the metal immersed as anode 22 in an aqueous anodizing electrolyte 21 and a cathode 24 e.g. of Pb or graphite immersed in a non- polarizing electrolyte 25, the electrolytes being separated by at least one cationic permselective membrane 26, e.g. of PVC provided in the walls of at least one membrane cell 23, to prevent deleterious reaction between the anodizing electrolyte 21 and the cathode. For forming a hard coloured anodized oxide coating on Al, the anodizing electrolyte contains a metal ion, e.g. of Fe, Cu, Ni, Co or Mn, and preferably comprises (a) 0À05 to 4À5% M 2 SO 4 , (b) 0À5% to saturation of an aliphatic and hydroxy mono- or di-carboxylic acid, e.g. oxalic, glycolic, lactic, malic, malonic, succinic or maleic acid, and (c) 0À1% to saturation of a metal salt of the acid (b), e.g. ferric oxalate. (a) may be another acid, such as nitric, boric, hydrofluoric, sulphamic or tartaric acid. The non-polarizing electrolyte may be a solution of sulphuric, phosphoric, chromic or oxalic acid, preferably a 4 to 35% H 2 SO 4  solution. The C.D. may range from 12 to 60 A. S. F. The permselective membrane may be a sulphonated crosslinked polymer of styrene or phenol-aldehyde condensation product, polystyrene-divinylbenzene or divinylbenzene-olefinic carboxylic acid forming copolymer, or a condensation polymer of resorcinol dimethyl ether sulphonic acid and formaldehyde.
Patent GB-1234100-A (GB)
IPC: C07D251/18
Filed: 1968-08-15
Abstract: 1,234,100. Substituted guanamines. ARMOUR PHARMACEUTICAL CO. 15 Aug., 1968 [16 Aug., 1967], No. 39087/68. Heading C2C. [Also in Division A5] The invention comprises compounds of formula and their non-toxic acid addition salts, wherein R is C 3-5  or C 7-10  cycloalkyl, 1- or 2-cyclohexenyl, norbornyl, or phenylcyclopropyl. These compounds are prepared by refluxing RCN with dicyandiamide, in ethyleneglycol mono-methyl or -ethyl ether, in presence of a basic catalyst such as KOH. In Example V, 6 - cyclohexylguanamine is prepared by hydrogenating 6- (3<SP>1</SP>-cyclohexenyl)guanamine. Therapeutic compositions for treating inflammatory conditions comprise the above compounds with conventional adjuvants. Administration may be oral, topical, intravenous or pancaval.
Patent GB-1237971-A (GB)
IPC: E06B9/388
Filed: 1969-02-28
Abstract: 1,237,971. Venetian blinds. LEVOLOR LORENTZEN Inc. 28 Feb., 1969 [27 May, 1968], No. 10798/68. Heading E1J. A cover or "ladder-cap" 20 made entirely of plastics injection moulded in one piece for the bottom of the lower bar 40 of a Venetian blind which bar may be of sheet steel and is of oval cross-section having a longitudinal split 49 in its upper side and with the lift cord 80 passing therethrough and with the ladder longitudinal elements 72, 73 passing around the front and rear walls 42, 43 of the bar comprises a base to underlie the bottom of the bar, front and rear walls 22, 23 extending upwardly from the base to tie along side the front and rear walls 42, 43 of the bar and studs 31, 32 extending upwardly from the base between the walls to project tightly through holes 51, 52 in the bottom of the bar. The ladder-cap also has ribs 25, 26 on the outer side and channels 27, 28 opening inwardly for the passage of ladder elements 72, 73 which have at their ends fittings 75 to be passed through holes 45, 47 in the bottom of the bar to anchor the ladder element 72, 73 in the bar. The lift cord 80 is passed down through hole 46 and up through hole 48 and knotted at its end, the cord on the outside of the bar being accommodated in a hollow depression in the bottom of the cap into which the channels 27. and 28 run as indicated by the broken line in Fig. 4. The holes 51, 52 in the bar through which the studs 31, 32 are secured are formed with two diametrically opposite flat faces and with jagged edges b, Fig. 10 to ensure tightness of the studs in the hole and prevention of the studs being withdrawn.