baber/WOPTO huggingface dataset:
Patent RU-2766190-C2 (RU)
Title: Compositions of antibodies against ror1 and corresponding methods
Inventor: RADER CHRISTOPH
IPC: A61K47/69
Filed: 2017-01-20
Granted: 2022-02-09
Abstract: FIELD: medicine. 
     SUBSTANCE: group of inventions relates to immunology and therapy of diseases or conditions associated with high expression of human ROR1. Proposed are antibodies specifically recognising human ROR1, antibody-drug conjugates (ADCs), chimeric antigenic receptors (CARs), compositions based thereon, and applications thereof. The antibody or the antigen-binding fragment of the antibody includes heavy and light chain CDRs sequences displayed in (1) SEQ ID NO:27 to 29 and SEQ ID NO:66 to 68; (2) SEQ ID NO:30 to 32 and SEQ ID NO:69 to 71; (3) SEQ ID NO:33 to 35 and SEQ ID NO:72 to 74; (4) SEQ ID NO:36 to 38 and SEQ ID NO:75 to 77; (5) SEQ ID NO:39 to 41 and SEQ ID NO:78 to 80; (6) SEQ ID NO:42 to 44 and SEQ ID NO:81 to 83; (7) SEQ ID NO:45 to 47 and SEQ ID NO:84 to 86; (8) SEQ ID NO:48 to 50 and SEQ ID NO:87 to 89; (9) SEQ ID NO:51 to 53 and SEQ ID NO:90 to 92; (10) SEQ ID NO:54 to 56 and SEQ ID NO:93 to 95; (11) SEQ ID NO: 57 to 59 and SEQ ID NO:96 to 98; (12) SEQ ID NO:60 to 62 and SEQ ID NO:99 to 101; or (13) SEQ ID NO:63 to 65 and SEQ ID NO:102 to 104. The proposed anti-ROR1 antibodies have high affinity. The CARs and CAR-T cells constructed using the above anti-hROR1 binding domains exhibit high effectiveness in vitro. The ADCs including the hROR1-specific antibody execute effective killing of hROR1-specific cells. 
     EFFECT: inventions allow for effective therapy of human cancer associated with the expression of ROR1. 
     37 cl, 29 dwg, 16 tbl, 23 ex
Patent RU-2740724-C2 (RU)
Inventor: MACKO JASON ANDREW
IPC: A24F40/42
Filed: 2017-08-02
Granted: 2021-01-20
Abstract: FIELD: vaping. 
     SUBSTANCE: invention relates to reservoir of ready composition for evaporation in electronic device for vaping. There is cartridge (70) made with possibility of containing ready composition for evaporation for electronic device (60) for vaping. Cartridge (70) comprises an inner portion and an outer portion configured to store the finished composition for evaporation. Outer part comprises multiple fibers (230) made so that they can be at least either mobile or substantially not tangled with each other. 
     EFFECT: invention provides longer service life of electronic device reservoir. 
     13 cl, 11 dwg
Patent RU-2753189-C2 (RU)
Title: System for preparing network traffic for quick analysis
Inventor: VARMENKHOVEN ADRIANUS
IPC: H04L12/26
Filed: 2017-11-17
Granted: 2021-08-12
Abstract: FIELD: communication. 
     SUBSTANCE: invention relates to a system and a method for preparing network traffic for analysis. A network stream is split into a set of standard network stream elements, which are then tagged. Tagged elements contain composite tagged elements, if necessary, can contain any type of element in accordance with any type of network stream standard, including, but not limited to, the IPFIX or Netflow standard, or can optionally be derived from such elements. 
     EFFECT: technical result is ensuring the possibility of efficient and fast splitting of network flows into useful information and its analysis. 
     23 cl, 7 dwg, 1 tbl
Patent RU-2713268-C2 (RU)
Title: Cybernetic device for control of underground leaching and method of its operation
Inventor: Lunev Petr Sergeevich
IPC: E21B43/28
Filed: 2019-08-15
Granted: 2020-02-04
Abstract: FIELD: mining. 
     SUBSTANCE: invention relates to mining, namely to underground leaching of useful ore components using automated control systems. Cybernetic device for control of process of underground leaching of useful components of ore, which includes self-adjustment unit as part of computer system and tuning unit, process stabilization unit as part of meter, converter, actuating unit and controller. At that, the self-adjustment unit contains sensors of input process parameters presented by the controllers of the leaching agent composition, its concentration, flow rate, pressure and temperature, output process parameters sensors, which are represented by controllers of the composition of the productive solution, its concentration, inlet, pressure, temperature and output of target priority useful component of ore, and in unit of process stabilization actuating unit and regulator contain scheme of leaching mode, decolmitation scheme, rock destruction scheme connected in series-parallel. 
     EFFECT: technical result consists in implementation of cybernetic approach to geotechnical development of deposit of solid minerals in uncrowded, efficient and ecological way. 
     10 cl, 4 dwg
Patent RU-2766440-C2 (RU)
Inventor: BERNSEN JOHANNES ARNOLDUS CORNELIS
IPC: H04L9/32
Filed: 2018-03-15
Granted: 2022-03-15
Abstract: Изобретение относится к системе беспроводной связи, которая обеспечивает одностороннюю аутентификацию устройства–ответчика посредством устройства–инициатора и взаимную аутентификацию обоих устройств. Технический результат заключается в недопущении длительных периодов тайм–аута во время беспроводной связи при одновременном обеспечении возможности инициатору также сообщать ошибки связи пользователю в течение короткого времени. Инициатор могут иметь модуль сообщений и конечный автомат. Инициатор запускается посредством получения общедоступного ключа ответчика через внеполосное действие и отправляет запрос на аутентификацию. Ответчик отправляет ответ по аутентификации, содержащий данные аутентификации ответчика на основе конфиденциального ключа ответчика и статус взаимного проведения, указывающий проведение взаимной аутентификации для обеспечения возможности устройству–ответчику получать общедоступный ключ инициатора через внеполосное действие ответчика. Конечный автомат инициатора выполнен с возможностью предоставлять состояние взаимной аутентификации, активированное при приеме статуса взаимного проведения, для ожидания взаимной аутентификации. 7 н. и 12 з.п. ф-лы, 8 ил.
Patent RU-2764344-C2 (RU)
Title: Curved sealing system
Inventor: JUAREZ ALEJANDRO
IPC: F16L21/00
Filed: 2018-04-25
Granted: 2022-01-17
Abstract: FIELD: sealing elements. 
     SUBSTANCE: invention relates to a sealing system connecting the first and the second tubular elements that contains the first curved sealing surface on the first tubular element and the second curved sealing surface on the second tubular element. Both the first and the second curved sealing surfaces are located between two sets of thread on the corresponding first and second tubular elements. When the first and the second tubular elements are in a joint configuration, the first and the second curved sealing surfaces contact and cross-interact, forming an annular curved medium seal. An auxiliary recess can be located adjacent to the first and/or the second curved sealing surfaces to accommodate the excess of lubricant between the first and the second tubular elements. 
     EFFECT: curved sealing system suitable for displacement or adjustment can be easier to operate and more reliable, since the medium seal can be maintained in different conditions. 
     20 cl, 10 dwg
Patent RU-2755864-C2 (RU)
Title: Безмасляный компрессор
Inventor: VAN HOVE LINUS
IPC: F04C29/12
Filed: 2018-03-13
Granted: 2021-09-22
Abstract: Изобретение относится к  безмасляному компрессору. Компрессор 1 содержит компрессорный элемент (2), включающий корпус (5), внутри которого установлены охватываемый и охватывающий винтовые роторы (6а) и (6b) соответственно. Вал (8) ротора (6b) переходит в ведомый вал (9). Двигатель (3)  имеет ведущий вал (13). Между валом (13) двигателя (3) и валом (9) элемента (2) имеется трансмиссия (4). Трансмиссия (4) содержит корпус (10) и, по меньшей мере, ведомое зубчатое колесо (11), установленное на валу (9), и ведущее зубчатое колесо (14), установленное на валу (13). В корпусе (10) выполнено выпускное отверстие (20), размещенное в радиальном продолжении одного из зубчатых колес (11, 14) и соединенное с отводной трубой (22). Труба (22) проходит в продолжении воздушного потока, создаваемого одним из зубчатых колес (11, 14), и соединена с масляным резервуаром (15) с фильтрующим элементом (16). Изобретение направлено на повышение эффективности компрессора. 2 з.п. ф-лы, 3 ил.
Patent RU-2759627-C2 (RU)
Title: Method for producing homo- and co-oligomers of αlfa-methylstyrene and isopentenes in presence of mesoporous aluminosilicate asm catalyst
Inventor: KUTEPOV BORIS IVANOVICH
IPC: C07C2/12
Filed: 2020-03-10
Granted: 2021-11-16
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to a method for catalytic production of homo- and co-oligomers of α-methylstyrene and isopentenes. The method is characterized by the fact that an amorphous mesoporous aluminosilicate ASM is used as a catalyst, the reaction is executed in chlorobenzene at a molar ratio of α-methyl styrene:isopentenes = 1:1.5 to 2, the amount of the catalyst of 5 to 20% wt. per the mixture of initial unsaturated compounds, at 20 to 65°C, atmospheric pressure, for 3 to 5 hours. 
     EFFECT: effective method for producing a mixture of homo- and co-oligomers of α-methylstyrene with isopentenes, making it possible to obtain target compounds with a good yield, under mild conditions. 
     1 cl, 1 tbl, 10 ex
Patent RU-2769887-C2 (RU)
Inventor: Brizitskij Leonid Ivanovich
IPC: G01D5/353
Filed: 2020-09-28
Granted: 2022-04-07
Abstract: FIELD: measuring equipment. 
     SUBSTANCE: invention relates to measuring equipment using optical fiber, namely, to fiber-optic security detectors, as well as to products, methods and means related to fiber-optic security detectors and their aspects. A fiber-optic security detector is claimed, including combined interferometers, containing a station part with a transceiver device connected to the linear part of the mentioned detector. In this case, the linear part is a branched optical circuit based on splitters and fiber-optic cable, which, by means of connecting couplings and a transport cable, connect the transceiver device and sensitive elements of the fiber-optic security detector, containing closed loops forming reflection signals, in which the same optical fiber segments of the cable are sensitive elements of interferometers, in which a phase shift of a probing pulse is created in accordance with exerted physical impact, same for both loops. In this case, one closed loop is a Mach-Zehnder interferometer, and the other closed loop is a Sagnac interferometer.  
     EFFECT: increasing the accuracy of determining the place of impact on the sensitive element; ensuring uniform sensitivity of the sensitive part of the fiber-optic security detector; increasing the reliability of the fiber-optic security detector; simplifying installation due to eliminating the need to use compensation coils in its composition, necessary to compensate for the length of fibers of the sensitive element; as well as the implementation of its purpose. 
     10 cl, 12 dwg
Patent UA-57841-C2 (UA)
Title: Method and device for exciting seismic waves
Inventor: PYGNASTIY SERHIY SERHIYOVICH
Filed: 2000-11-13
Abstract: The proposed method for exciting seismic waves and a device for the realization of the method can be used in geological prospecting of mineral resources and in seismic investigations. The proposed method consists in using an electromechanical converter with an active element and a reactive element that are installed with the possibility to rotate relative to each other. To the input winding of the converter, current pulses are applied that are converted into force pulses that act on the controlled medium via the active element of the converter. The proposed method differs in that the active element and the reactive element of the converter are at first set in a specified initial position, in which the corresponding initial inductance of the converter exceeds its minimal inductance, and then the rotation of the active element is provided when concurrently applying current pulses to the input winding of the converter. The length of the said pulses is equal to or less than the length of the time interval within which the inductance of the converter changes from the initial value to the maximal one. In the initial position of the active element and reactive element of the converter, a static force is provided with which the said elements interact with each other. A device for the realization of the proposed method contains a support plate, an electromechanical converter designed as a motor coupled with the active element of the converter, a platform for positioning the motor, and a crank gear for transmitting forces and linear motions. The platform is coupled with the support plate via springs. The present invention provides for improving the parameters that are characterize economic effectiveness of geological prospecting and reliability of the equipment used.
Patent UA-66913-C2 (UA)
Title: Tungsten carbide coatings (variants), a method for manufacture thereof and composite material (variants)
Inventor: LAKHOTKIN YURII VIKTOROVYCH
IPC: C01B32/949
Filed: 1999-02-11
Abstract: The present invention relates to new tungsten carbides which are doped with fluorine in an amount of up to 0,5wt% and which can also be doped with fluorocarbon compositions. These tungsten carbides are produced according to a new CVD method in which the phase contains tungsten bexafluoride, hydrogen and a carbon-containing gas. This method is characterised in that the carbon-containing gas is previously thermally activated. The tungsten carbide coatings can be applied onto construction material and articles made therefrom. These coatings exhibit a high wear and corrosion resistance as well as a high chemical stability.
Patent UA-72587-C2 (UA)
Title: Pharmaceutical combination of aselastin and leukotriene antagonist for treating rhinitis and conjunctivitis, pharmaceutical composition and method for its manufacture
Inventor: ENGEL JUERGEN
IPC: A61K31/405
Filed: 2001-05-02
Abstract: The invention relates to a pharmaceutical combination to be administered topically or orally of a non-sedative antihistamine, with the exception of compounds of the loratadine type, and a leukotriene antagonist, selected from a leukotriene D4 antagonist, or a 5-lipoxygenase inhibitor, or a FLAP antagonist and optionally conventional, physiologically acceptable carriers, extenders and auxiliary agents, for the prophylaxis and treatment of allergic and/or vasomotor rhinitis or allergic conjunctivitis.
Patent UA-74834-C2 (UA)
Title: Non-nucleoside inhibitors of reverse transcriptase and a pharmaceutical composition based thereon
IPC: A61K/
Filed: 2001-06-14
Abstract: Provided are compounds of general formula (I), wherein R2 is selected from the group consisting of H, F, Cl, (Ñ1-4) alkyl, (C3-4)cycloalkyl and ÑF3; R4 is H or Me; R5 is H, Me or Et, with the proviso that R4 and R5 are not both Me, and if R4 is Me then R5 cannot be Et; R11 is Et, cyclopropyl, propyl, isopropyl, or isobutyl; and Q is selected from the group consisting of (II), (III), (IV) and (V); and pharmaceutically acceptable salts thereof, as inhibitors of HIV reverse transcriptase, wild-type and several mutant strains. (I) (II), (III), (IV), 3 (V)
Patent UA-75311-C2 (UA)
Title: Cryoapplicator for freezing biological objects
Inventor: ZHARKOV YAROSLAV VASYLIOVYCH
IPC: A61B18/02
Filed: 2005-10-04
Abstract: The cryoapplicator for freezing the biological objects consists of the cylindrical housing with the lines for direct and reverse flow of cryoagent inside. The internal surface of the housing has the longitudinal edges. The hosing is made of the low heat conductivity metal. The internal surface of the edges is covered by thin copper layer. The ring-shaped layer of the porous structure is welded to this copper layer. The porous structure is designed as the welded disoriented pieces of the copper wire, which are compressed until the specified state. The porosity percentage and the size of the pores increase with the distance away from the edges.
Patent UA-83659-C2 (UA)
Title: P2x7 receptor antagonists and their use, pharmaceutical composition based thereon, process for the preparation thereof (variants)
Inventor: EVANS RICHARD
IPC: C07D215/38
Filed: 2004-01-06
Abstract: The invention provides compounds of formula (ІA), processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.
Patent UA-77377-C2 (UA)
Title: Method for using the number resource in servicing subscribers of a public telephone network and new communication systems; automated system for accounting and allocating number resource
Inventor: HORYTSKYI VIKTOR MYKHAILOVYCH
IPC: H04M3/00
Filed: 2006-05-23
Abstract: It is proposed a method for using the number resource in servicing subscribers of a public telephone network and new communication systems as well as a system for accounting and allocating number resource that are distinctive by controlling the increment per a unit time interval of the following functional (??): , where Z is the number of time intervals Tp from the start of the system to the current time interval, within which the resource utilization factor (?p) was constant, N?p is the unused (undistributed) resource within the time interval Tp, Yp is the number of additional services within the time interval Tp, Dik, Djk are the volumes of the mandatory and additional services of the communication system for an arbitrary subscriber, Pi, Pj are the amounts of payment for the mandatory and additional services, ?I, ?j are the coefficients that account for distances in providing the mandatory and additional services, Em are the expenses of the operator for designing and agreeing the design of the communication system, En are the expenses of the operator for constructing the system, Eqnp are the expenses of the operator for maintaining one number per the time interval Tp. The advantage of the proposed method is its enhanced efficiency in using the number resource of a communication system.
Patent UA-82012-C2 (UA)
Title: Radar system
Inventor: HUZ VOLODYMYR IVANOVYCH
IPC: G01S13/02
Filed: 2006-10-06
Abstract: The invention relates to coherent-pulse radar systems (RS) intended for reveal of air, surface and over-water objects, measurement of coordinates of those and tracking of revealed objects, determination of parameters of motion of those are issue of data to complexes and systems connected to it. RS performs radiation of low-power signals, this provides energy saving and decreases ecological damage to environment, provides use of high-efficiency methods of digital forming and digital processing of radar signals and radar data, it has high reliability and safe operation due to broad use of digital processors, microelectronic elements with high level of integration and powerful SHF semiconductor elements and modules. RS provides coherent collection of energy of signals through use of current quick Fourier transform with large dimensionality and provides simultaneous effective suppression of pulse, movable and fixed obstacles through use of set of additional units, in particular combinatory unit, circuits for maximum selection; calculators for current level of obstacles, calculators of threshold levels from noise and obstacles and resulting threshold levels; adder, threshold circuit, calculators of numbers of frequency channels affected with obstacles, circuits for suppression of frequency channels and time suppression.
Patent UA-87780-C2 (UA)
Title: Transformer conservator insulation valve (tciv)
Inventor: VAKHAURE V K
IPC: H01F27/00
Filed: 2006-04-13
Abstract: A Transformer conservator Isolation Valve, (TCIV) comprising of an inlet conduit or pipe (2), outlet conduit, or pipe (5) connected to a rectangular housing (7) with an operating device. (10) fixed on a shaft (19) placed inside, the rectangular housing (7) and lever (9) for locking of the operating device (10); the said operating device (10) is provided with a scaling gasket (20) fitted such that during flow of oil due to rupture of electrical transformer tank or bursting of electrical transformer bushing or draining of oil swings towards the outlet conduit or pipe (5) so as to restrict flow of oil from the electrical transformer conservator (1) to the electrical transformer tank (4), during filtration or filling or refilling, a handle (8) is provided with the operating device (10) outside the rectangular housing (7) which turns anti-clockwise during operation, the operating device (10) does not restrict flow of oil from the electrical transformer Conservator (1) during filtration or filling or refilling, two locking plates (13 and І4) provided outside the rectangular housing.
Patent UA-96748-C2 (UA)
Title: Use of benzo-fused helerocycle sulfamide derivatives for the treatment of obesity
Inventor: SMITH-SWINTOSKY VIRGINIA L
IPC: A61P3/04
Filed: 2006-12-19
Abstract: The present invention is a method for the treatment of obesity, for promoting weight loss and/or suppressing appetite comprising administering to a subject in need thereof a therapeutically effective amount of one or more novel benzo-fused helerocycle sulfamide derivatives of formula (I) as herein defined.
Patent UA-95023-C2 (UA)
Title: Wind-driven power plant
Inventor: MILINSKYI YURII MYKOLAIOVYCH
IPC: F03D7/02
Filed: 2010-03-25
Abstract: A wind-driven power plant has a mast that is arranged as two tubes installed in telescopic way, connected in hinged way with thrust bearing. The lower tube has larger diameter, its upper part is connected with four guys to anchors fixed in earth, and the lower end rests on foundation in hinged way. The ends of the tube are connected by four rods that go from the end of the tube with cross piece, with formation of spatial truss. The upper tube has smaller diameter, at its upper end horizontal axle is fixed, this is hinged to wind wheel of bicycle type. The wind wheel is arranged as connected to each other two-row bushing, spokes and rim. Face area of the rim is covered with rigid cowl, and at the outer surface of the rim set of blades if fixed. Free ends of the blades are connected to each other with outer rim with bended edge as confuser. The wind wheel is connected by gearing to electric generator fixed to the tube with a holder. To the tube with the middle section guide rod is attached, with guide blade at the end, this can rotate in free way within right angle between two restrictors arranged as rods fixed with the ends to the tube in horizontal plane. Guide rod is pressed to one of restrictors, it is parallel to axis of the working wheel. Free end of the restrictor is connected to load with cable that goes through block at the middle section of the guide rod and block at its free end. Free end of the other restrictor is connected to parachute with cable that goes through the block at the middle section of guide rod and guide ring at its end.
Patent UA-101001-C2 (UA)
Title: method for producing faces of collinear crystallographic axis c in layered crystals of InSe and GaSe
Inventor: KOVALIUK ZAKHAR DMTROVYCH
IPC: C30B11/00
Filed: 2010-06-24
Abstract: The invention relates to the field of chemistry and can be used for producing the diode structures. A method for producing faces of collinear crystallographic axisin layered crystals of InSe and GaSe consists in growing a layered crystal in a quartz ampoule. Before growing quartz plate is placed in ampoule, then a pre-synthesized material is placed there. The invention allows to manufacture samples of given size, provides saving of material, gives the possibility to avoid the mechanical treatment of the frontal surface of the crystal layers.