baber/WOPTO huggingface dataset:
Patent NZ-523836-A (NZ)
Title: Somatostatin analogues
Inventor: ALBERT RAINER
IPC: A61P9/08
Filed: 2001-07-30
Abstract: The compound as disclosed for use in combination with an immunosuppressive agent, an anti-=inflammatory agent, a GH secretagogue receptor modulating agent, a GH receptor antagonist, an insulin secretagogue, an insulin secretion enhancer, an insulin sensitizer, a low dose of insulin, an agent having anti-angiogenetic effects or a chemotherapeutic agent. The compound as disclosed may also be used to treat or prevent conditions associated with excess GH secretion and or excess of IGF-1 and other metabolic disorders relating to insulin or glucagon release, irritable bowel syndrome, diarrhoea, pancreatitis, macular oedema, proliferative retinopathy and restenosis for example.
Patent NZ-526183-A (NZ)
Title: A filter unit for filtering gas
Inventor: SIMONSEN PER
IPC: B01D46/04
Filed: 2000-11-02
Abstract: A filter unit (1) for filtering gas has a plurality of bag filters (10) hanging down from a suspension plate (7) dividing a housing into a lower gas inlet side (9) and an upper outlet side (8) for filtered gas. The individual bag filter (10) has an open end (11) at the suspension plate, a tubular wall (20) of a flexible filter material, and a lower end closure (23) of an impermeable material and provided with a drain (25). The end closures of the bag filters are interconnected.
Patent NZ-526783-A (NZ)
Title: (Diazolo-pyridinyl)-pyrimidines for use in treatment of CNS disorders and diabetes
Inventor: BERG STEFAN
IPC: A61P25/14
Filed: 2002-02-18
Abstract: Disclosed are compounds of formula (I), wherein: Ring A is imidazo[1,2a]pyrid-3-yl or pyrazole[2,3a]pyrid-3-yl, Ring B is pyridine or pyrimidine, Ring C is a phenyl ring or heteroaromatic ring containing heteroatoms selected from N, O and S, Ring D is a phenyl ring or heteroaromatic ring containing heteroatoms selected from N, O and S, wherein it is optionally fused with another ring containing atoms selected from C, N, O and S, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for use in the treatment and/or prophylaxis of conditions associated with inhibition of glycogen synthase kinase-3.
Patent NZ-527587-A (NZ)
Title: A bacterial strain, processed plant extracts and probiotic compositions for human and veterinary use
Inventor: OLSHENITSKY MARK
IPC: A23K1/00
Filed: 2000-06-01
Abstract: A process of preparing a volatile fraction of a plant is disclosed, wherein the process comprises the steps of: (a) grinding a plant material to give a plant biomass; (b) mixing the plant biomass with water at a weight ration of 3 parts water to 1 part biomass and stirring the same for at least 2 hours at ambient temperature, to thereby obtain a water extract of said plant biomass; (c) steam distilling the mixture obtained in step (b) under a pressure that ranges from 5 to 10mbar and at a bath temperature not exceeding 38° C; and (d) collecting the volatile fraction obtained by said steam distillation, which fraction may be further diluted with a suitable buffer. Also disclosed is a formulation having a biologically or therapeutically beneficial effect comprising at least one volatile fraction (VF) of a plant extract, wherein the plant extract is obtained by water extraction and the volatile fraction being prepared by steam distillation of said plant extract under reduced pressure that ranges from 5 to 10mbar and at a bath temperature not exceeding 38° C. (62) Divided out of 515830
Patent NZ-533408-A (NZ)
Title: A grafted antibody that has specific binding activity for cryptic collagen epitope and contains CDR regions
Inventor: WATKINS JEFFRY D
IPC: C07K16/30
Filed: 2002-11-26
Abstract: A grafted antibody, or a functional fragment, comprises one or more complementarity determining regions (CDRS) that has a least one amino acid substitution in one or more CDRs of a heavy or light chain CDR selected from a specific group. The grafted antibody has specific binding activity for a cryptic collagen epitope. The antibody can be used to inhibit angiogenesis, tumour growth and metastasis.
Patent NZ-535438-A (NZ)
Title: Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
Inventor: LESAGE ANNE SIMONE JOSEPHINE
IPC: C07D221/10
Filed: 2003-03-26
Abstract: Disclosed are radiolabelled compounds of Formula (I-A)* or (I-B)*, N-oxide forms, pharmaceutically acceptable addition salts and stereochemically isomeric forms wherein the substituents are as described in the specification. Compounds of this type are useful for the marking or identifying mGlu1 receptors in biological material and for imaging organs.
Patent NZ-536114-A (NZ)
Title: 4-(N-phenylamino)-quinazolines / quinolines as tyrosine kinase inhibitors
Inventor: HIMMELSBACH FRANK
IPC: A61K31/553
Filed: 2003-03-25
Abstract: Disclosed are bicyclic heterocycles of the general formula (I), wherein R<A>, R<B>, R<C>, R<D> and X are defined as in claim 1, the tautomers, stereoisomers, mixtures and salts thereof, especially the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, especially an inhibitory effect on tyrosine kinase-mediated signal transduction. Also disclosed is the use of the bicyclic heterocycles in the treatment of diseases, especially cancer diseases and of benign prostate hyperplasia (BPH), of diseases of the lung and the respiratory system, and further to the production of the bicyclic heterocycles.
Patent NZ-542316-A (NZ)
Title: An expression cassette and vector for transient or stable expression of exogenous molecules
Inventor: SISK WILLIAM P
IPC: C12N15/85
Filed: 2004-02-13
Abstract: An expression cassette comprises a human CMV immediate early 1 (hCMV IE1) promoter/enhancer, a polynucleotide of interest and a variant human growth hormone (hGHv) polyA signal domain or variant thereof. The polynucleotide of interest encodes a therapeutic agent.
Patent NZ-544955-A (NZ)
Title: Liquid herbicide formulation for plant protection
Inventor: DECKWER ROLAND
IPC: A01N43/653
Filed: 2004-07-15
Abstract: The disclosure relates to a liquid formulation comprising: (a) one or more herbicidally active compound from the group of sulfonamides which are ALS inhibitors (acetolactate synthetase inhibitors), preferably the sulfonamides are from the group of triazolopyrimidinesulfonamides, sulfonylaminocarbonyltriazolinones and sulfonylureas; (b) one or more organic solvents, preferably from the group of unsubstituted or substituted hydrocarbons, polar solvents and fatty acid esters; and (c) one or more inorganic salts, preferably from the group of carbonates, bicarbonates, hydroxides, oxides, hypochlorites and sulfites.. Said liquid formulation is suitable for using in the field of plant protection.
Patent NZ-545185-A (NZ)
Title: Mutations in ion channels
Inventor: MULLEY JOHN CHARLES
IPC: C12Q1/68
Filed: 2004-08-06
Abstract: Disclosed is a method of identifying a subject predisposed to epilepsy, comprising ascertaining whether the gene encoding the a-I sodium channel subunit (SCNIA) in said subject has undergone a c1237T-A mutation.
Patent NZ-545979-A (NZ)
Title: Novel adenosine A3 receptor agonists
Inventor: BARALDI PIER GIOVANNI
IPC: G01N33/74
Filed: 2004-09-17
Abstract: Disclosed is a compound of formula 1 wherein Ar is an aryl group; and wherein the rest of the substituents are defined within the specification; or a pharmaceutically acceptable salt thereof. Also disclosed is the use of the above compound in the manufacture of a medicament for the treatment of a medical condition that is mediated by the A3 receptor.
Patent NZ-550109-A (NZ)
Title: Adhesion promoting compound
Inventor: DUNCAN ROBERT HUME
IPC: C09D11/03
Filed: 2005-03-17
Abstract: Disclosed is an adhesion promoter suitable for use in printing ink formulations, comprising the product of (a) mixing a solution of a polymer or synthetic resin with an organophosphorus compound, and then (b) mixing the mixture formed in (a) with a titanium compound selected from one or more of the group consisting of a titanium halide, titanium alkoxide, titanium halo-alkoxide or a condensed titanium alkoxide.
Patent NZ-550358-A (NZ)
Title: A flow control assembly for a shower head with flow restrictor in each of hot, cold and downstream lines
Inventor: MCDONALD CHRISTOPHER WILLIAM
Filed: 2006-10-06
Abstract: A shower assembly ( 10 ) including a shower head ( 11 ) to receive water from a cold water tap ( 12 ) and a hot water tap ( 13 ). Each of the taps ( 12, 13 ) has a tap body ( 20 ) within which there is located a flow restriction device. A further flow restriction device is located downstream of the two flow restriction devices.
Patent NZ-551767-A (NZ)
Title: A process and an arrangement for the handling and distribution of financial and other commercially sensitive information without disclosing it to a third party
Inventor: CHEVENKOVA NATALIE
IPC: G06N5/00
Filed: 2009-09-30
Abstract: A financial reporting process includes an artificial intelligence accounting system administrator party maintaining an artificial intelligence accounting system that simulate an intelligent behaviour of an accounting services party. The artificial intelligence accounting system is a part of a computer application, in condition that ensure processing of records of financial activity related to business events and expressed in business terms familiar for a reporting entity party in accordance with current accounting practices and business law. The reporting entity party records records of financial activity related to business events and expressed in business terms familiar for the reporting entity party into the computer application. The artificial intelligence accounting system process the records of financial activity related to business events and expressed in business terms familiar for the reporting entity party in the computer application. The reporting entity party or an information user party requests financial reports which are generated by means of the artificial intelligence accounting system and distributed in accordance with the request.
Patent NZ-552080-A (NZ)
Title: 9-cis-retinyl esters and uses thereof
Inventor: PALCZEWSKI KRZYSZTOF
IPC: A61K31/22
Filed: 2005-06-20
Abstract: Disclosed is the use of a retinal derivative in the preparation of a medicament for use in the treatment of an endogenous 11-cis-retinal deficiency in the eye of a human subject, wherein the derivative has a structure represented by Formula I, wherein A is CH2OR, CH(OH)OR, CH(ORa)ORb or CH=NOH and each R, Ra, and Rb is an aldehydic group, an alkane group, a carboxylate group, an alcohol group or a carboxylic acid, with the proviso that if the retinal derivative is a 9-cis-retinyl ester, the ester substituent comprises a carboxylate radical of a C1 to C10 monocarboxylic acid or a C2 to C22 polycarboxylic acid. Also disclosed is a pharmaceutical composition comprising i) a retinal derivative as defined above; and ii) a pharmaceutically acceptable vehicle, wherein said composition is formulated for oral administration, or an opthalmalogically acceptable vehicle, wherein said composition is formulated for opthalmalogical administration. Of particular importance is the use of the retinal derivatives 9-cis-retinyl succinate, 9-cis-retinyl citrate, 9-cis-retinyl ketoglutarate, 9-cis-retinyl fumarate, 9-cis-retinyl malate and 9-cis-retinyl oxaloacetate.
Patent NZ-552255-A (NZ)
Title: Drum with alteration of range of sounds when struck externally, and internal drum stick that partially rotates to strike
Inventor: ASPLAND MARK
IPC: G10D13/18
Filed: 2005-05-27
Abstract: A drum shown in schematic plan view and forming a resonant chamber has means (not shown) for altering a range of sounds when an external surface is struck and typically the means are internal snares that are movable towards and in contact with or away from an internal surface of the drum. An internally located drum stick 30 is located within the chamber and has handle and head and can be partially rotated so as to strike an inner surface of the drum. The stick is typically actuated by a foot pedal 40 and is biased away from the surface.
Patent NZ-553385-A (NZ)
Title: Methods and apparatus to monitor audio/visual content from various sources
Inventor: RAMASWAMY ARUN
IPC: H04N5/44
Filed: 2005-08-09
Abstract: A multi-engine meter to monitor media content provided by a selected one of a plurality of media content sources for presentation by an information presenting device is disclosed. The multiengine meter comprises at least one audio engine to process audio samples corresponding to the monitored media content; at least one video engine to process video samples corresponding to the monitored media content; at least one metadata engine to process at least one of the audio samples or the video samples; and a decision processor to evaluate a decision tree comprising at least two decision nodes to identify the selected one of the plurality of media content sources. Each decision node of the decision tree corresponds to a decision metric evaluated using information generated by at least one of the at least one audio engine, the at least one video engine or the at least one metadata engine. A second decision node of the decision tree is selected for evaluation based on an outcome of evaluating a preceding first decision node of the decision tree.
Patent NZ-556659-A (NZ)
Title: Prevention of HIV-infection with TMC278, 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
Inventor: BAERT LIEVEN ELVIRE COLETTE
IPC: A61P31/18
Filed: 2006-04-04
Abstract: Disclosed is the use of a parenteral formulation comprising an effective amount of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile (also known as TMC278), or an acid-addition salt thereof, and a carrier, to provide long term prevention of HIV infection in an individual at risk of being infected by HIV, wherein the medicament is adapted for administration subcutaneous or intramuscularly and wherein the time interval between administrations is at least two weeks.
Patent NZ-561697-A (NZ)
Title: Screw in ship anchor with adjustable mooring collar
Inventor: FIELDER GRAHAM CLYDE
IPC: B63B21/50
Filed: 2007-09-19
Abstract: An anchor for difficult founding conditions includes a shaft 10 with a drill auger 13 at one end and a driving connection 15 at the other end, a ring bolt 17 that can slide and rotate on the shaft, and a shaft clamp 18. The anchor is suspended above the seabed and the shaft is turned via the driving connection 15 so that the auger drills into the seabed until the anchor is sufficiently embedded. The ring bolt 17 is slid down the shaft so as to be adjacent the seabed, and the clamp 18 is tightened to prevent the ring bolt from riding up the shaft. The hawser 20 for the vessel to be anchored is attached to the ring bolt 17.
Patent NZ-566984-A (NZ)
Title: Methods for enhancing the degradation or conversion of cellulosic material
Inventor: HARRIS PAUL
IPC: C12N9/42
Filed: 2006-09-29
Abstract: Disclosed is a method for degrading or converting a cellulosic material, comprising: treating the cellulosic material with an effective amount of one or more cellulolytic proteins in the presence of an effective amount of a polypeptide having cellulolytic enhancing activity, wherein the presence of the polypeptide having cellulolytic enhancing activity increases the degradation of cellulosic material compared to the absence of the polypeptide having cellulolytic enhancing activity and wherein the polypeptide having cellulolytic enhancing activity is selected from the group consisting of: (a) a polypeptide comprising an amino acid sequence which has at least 70% identity with the mature polypeptide of SEQ ID NO: 2; (b) a polypeptide encoded by a polynucleotide which hybridizes under at least high stringency conditions with (i) the mature polypeptide coding sequence of SEQ ID NO: 1, (ii) the genomic DNA sequence comprising the mature polypeptide coding sequence of SEQ ID NO: 1, or (iii) a full-length complementary strand of (i) or (ii); and (c) a functional variant comprising a substitution, deletion, and/or insertion of one or more amino acids of the mature polypeptide of SEQ ID NO: 2, provided that the functional variant has at least 70% identity with the mature polypeptide of SEQ ID NO: 2. Further disclosed is a method for producing a fermentation product, comprising: (A) saccharifying a cellulosic material with an effective amount of one or more cellulolytic proteins in the presence of an effective amount of the polypeptide having cellulolytic enhancing activity, wherein the presence of the polypeptide having cellulolytic enhancing activity increases the degradation of cellulosic material compared to the absence of the polypeptide having cellulolytic enhancing activity and wherein the polypeptide having cellulolytic enhancing activity is selected from the group consisting of: (i) a polypeptide comprising an amino acid sequence which has at least 70% identity with the mature polypeptide of SEQ ID NO: 2; (ii) a polypeptide encoded by a polynucleotide which hybridizes under at least high stringency conditions with (a) the mature polypeptide coding sequence of SEQ ID NO: 1, (b) the genomic DNA sequence comprising the mature polypeptide coding sequence of SEQ ID NO: 1, or (c) a full-length complementary strand of (a) or (b); and (iii) a functional variant comprising a substitution, deletion, and/or insertion of one or more amino acids of the mature polypeptide of SEQ ID NO: 2, provided that the functional variant has at least 70% identity with the mature polypeptide of SEQ ID NO: 2; (B) fermenting the saccharified cellulosic material of step (a) with one or more fermenting microorganisms; and (C) recovering the fermentation product from the fermentation.
Patent NZ-567818-A (NZ)
Title: Annular submersible vehicle comprising the means for rolling about the duct
Inventor: GOSLING HARRY GEORGE DENNIS
IPC: B63H1/16
Filed: 2006-10-19
Abstract: A submersible vehicle (1) having an outer hull (2) is disclosed. The outer hull (2) defines a hull axis (3) and appears substantially annular when it is viewed along the hull axis (3). The interior of the annulus defines a duct (5) that is open at both ends. When the vehicle (1) is submerged in a liquid or water, the liquid or water floods the duct. The vehicle (1) also comprises means for rolling the vehicle (1) about the duct (5).
Patent NZ-568106-A (NZ)
Title: Methods of making modular fusion protein expression products
Inventor: REED THOMAS
IPC: C12N9/64
Filed: 2006-10-19
Abstract: Disclosed is a vector comprising each of the following elements arranged sequentially to form a module open reading frame, said vector comprising a) a first restriction site that codes for a first group of amino acids, wherein the first group of amino acids comprises at least two amino acids; b) a first open reading frame coding for a polypeptide of interest, wherein the coding sequence of the polypeptide of interest is in frame with the coding sequence of at least two amino acids of the first restriction site; c) a second restriction site that codes for a second group of amino acids, wherein the second group of amino acids comprises at least two amino acids, wherein the coding sequence of the second group of amino acids of the second restriction site is in frame with the coding sequence of the polypeptide of interest of the first open reading frame, and wherein the polynucleotide sequence of the second restriction site is not the same as the polynucleotide sequence of the first restriction site; d) a spacer polynucleotide sequence, wherein the spacer polynucleotide sequence codes for at least three spacer amino acids, and wherein the coding sequence for the spacer sequence is in frame with the polynucleotide sequence of the second restriction site; and e) a third restriction site that codes for a third group of amino acids, wherein the third group of amino acids comprises at least two amino acids, wherein the coding sequence of the third group of amino acids of the third restriction site are in frame with the coding sequence of the at least three spacer amino acids and wherein the polynucleotide sequence of the third restriction site is not the same as the polynucleotide sequence of the first restriction site and the third restriction site is not the same as the polynucleotide sequence of the second restriction site, wherein elements (a) through (e) are in-frame linked to one another to form the module open reading frame, wherein the first restriction site is susceptible to a restriction enzyme that would produce a first single-stranded overhang comprising at least 2 nucleotides, wherein the second restriction site is susceptible to a restriction enzyme that would produce a second single-stranded overhang comprising at least 2 nucleotides, and wherein said first and second overhangs are complementary to one another, whereupon the annealing of the first and second overhangs, the first restriction site and the second restriction site are destroyed.
Patent NZ-569608-A (NZ)
Title: Tetralone-based monoamine reuptake inhibitors
Inventor: SHAO LIMING
IPC: A61K31/4706
Filed: 2006-12-21
Abstract: Disclosed is a dichloronathtelene and quinoline compounds having a structure of Formula (II), Formula (III), Formula (IV), or Formula (V), or a pharmaceutically acceptable salt or solvate thereof: wherein n is an integer selected from 0 to 2; D is CX-Ar1 or N-Ar1; m is 1; each X is independently H or OH; Ar1 is defined in the specification V and W are independently selected from H or OR9 ; wherein R9 is selected from H, alkyl, heteroalkyl, aryl, heteroaryl, and heterocycloalkyl; each R1 and R2 is independently H, halogen, CN, substituted or unsubstituted alkyl, or heteroalkyl; and R3 and R4 are independently H, alkyl, or heteroalkyl and any enantiomer, diastereoisomer, racemic mixture, enantiomerically enriched mixture, and enantiomerically pure form thereof. Also disclosed is the use of said compound for treating a central nervous system disorder, wherein said central nervous system disorder is selected from depression, fibromyalgia, pain, sleep apnea, attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), restless leg syndrome, schizophrenia, anxiety, obsessive compulsive disorder, post-traumatic stress disorder, seasonal affective disorder (SAD), premenstrual dysphoria, and a neurodegenerative disease.
Patent NZ-573919-A (NZ)
Title: A system for engaging heart tisue utilising a vacuum for percutaneous intravascular access to cardiac tissue
Inventor: KASSAB GHASSAN S
IPC: A61M25/06
Filed: 2007-06-29
Abstract: An engagement catheter (700) and system for engaging heart tissue is disclosed. The system includes an engagement catheter (700) having a proximal end (710), a distal end (720), and first (730) and second (740) lumens that extend between the proximal and distal ends. A vacuum port (770) is located at or near the proximal end (710) and is connected to the first lumen (730) which is in communication with a suction port (780) located at or near the distal end (720). The suction port (780) is configured to engage targeted tissue on an interior wall of a heart to form a reversible seal with the wall when a vacuum source is attached to the vacuum port (770). The system further includes a delivery catheter with a hollow tube capable of insertion into the second lumen (740) of the engagement catheter (700). The system is capable of enlarging a pericardial space between the targeted tissue and a pericardial sac that surrounds the heart by retracting the targeted tissue away from the pericardial sac.