baber/WOPTO huggingface dataset:
Patent EC-SP13012792-A (EC)
Title: Composiciones farmacéuticas que comprenden anticuerpos humanos frente a pcsk9
Inventor: HANOTIN CORINNE
IPC: C07K16/40
Filed: 2013-07-26
Abstract: La presente invención se refiere a Composiciones farmacéuticas que comprenden un anticuerpo que se une específicamente a la proproteínaconvertasasubtilisina/kexina tipo 9 humana (PCSK9), a métodos para tratar enfermedades o afecciones en las que la expresión o actividad de la proproteínaconvertasasubtilisina/kexina tipo 9 (PCSK9) ocasiona un impacto mediante la administración de anticuerpos específicos para PCSK9 o fragmentos de unión al antígeno de los mismos y preferiblemente mediante la administración adicional de un inhibidor de 3-hidroxi-3-metil-glutaril-CoA reductasa (HMG-CoAreductasa). La presente invención se refiere adicionalmente a anticuerpos específicos para PCSK9 o fragmentos de unión al antígeno de los mismos para su uso en el tratamiento de enfermedades o afecciones en las que la expresión o actividad de PCSK9 ocasionan un impacto.La presente invención también se refiere a artículos manufacturados que comprenden material de envasado, anticuerpos específicos para PCSK9 o fragmentos de unión al antígeno de los mismos, y una etiqueta o prospecto que indica qué grupos de pacientes pueden ser tratados con dichos anticuerpos o fragmentos, qué grupos de pacientes no deben ser tratados con dichos anticuerpos o fragmentos, y qué régimen de dosificación se debe utilizar.La presente invención se refiere adicionalmente a métodos para someter a ensayo la eficacia de anticuerpos específicos para PCSK9 o fragmentos de unión al antígeno de los mismos para el tratamiento de ciertas enfermedades o afecciones y para el tratamiento de subgrupos específicos de pacientes.
Patent EC-SP14013133-A (EC)
Title: Artefacto y método para preparar bebidas por infusión
Inventor: LAI KIN MAN
IPC: A47J31/02
Filed: 2014-01-13
Abstract: Un artefacto para preparar bebidas incluye un alojamiento que tiene un depósito de líquido y un receptáculo en el alojamiento dimensionado para recibir un envase que contiene al menos un ingrediente de bebida que tiene partículas de un primer tamaño. El receptáculo puede pivotarse de una primera posición en la que el receptáculo gira hacia un frente del artefacto y una segunda posición en la que el receptáculo se alinea con un cabezal de infusión y entra en contacto con él. El artefacto para preparar bebidas además incluye un mecanismo para transformar las partículas de los ingredientes de bebida del primer tamaño a un segundo tamaño dentro del recipiente, siendo el segundo tamaño menor que el primer tamaño.
Patent EE-200200153-A (EE)
Inventor: VOGT SEBASTIAN
IPC: A61L27/54
Filed: 2002-03-22
Abstract: An amphiphilic organic sulfate, sulfamate, sulfonate, disulfate, disulfonate or trisulfonate is included in an aminoglycoside, lincosamide, 4-quinolone or tetracycline antibiotic preparation to retard the release of the antibiotic from the preparation. An antibiotic preparation comprises a mixture of an amphiphilic component consisting of one or more alkyl, aryl, alkylaryl, cycloalkyl or alkylcycloalkyl sulfates, sulfamates or sulfonates, fatty acid-2-sulfonates, alkyl or cycloalkyl disulfates, alkyl, cycloalkyl, aryl or alkylaryl disulfonates or aryl or alkylaryl trisulfonates and one or more aminoglycoside, lincosamide, 4-quinolone or tetracycline antibiotics.
Patent GB-185500900-A (GB)
IPC: C11B11/00
Filed: 1855-04-21
Granted: 1855-10-12
Abstract: 900. Schaeffer, W. C. T. April 21. Fats.-The waste wash-waters, of wool and other mills, are run into tanks and treated with solutions of alum, magnesium sulphate, rock salt, " potash " salt," &c., to cause the fatty matters to separate. The fatty matters are filtered, freed from water by evaporation, and treated with hydrochloric or other acid.
Patent GB-189705987-A (GB)
Title: Improvements in or connected with Milk Tubes or Catheters for the use of Veterinary Surgeons.
Inventor: TUTT JOHN BOON
Filed: 1897-03-06
Granted: 1898-02-26
Abstract: 5987. Tutt, J. B. March 6. Catheters.-A milk tube or catheter A, B, for the use of veterinary surgeons, is furnished with two springs or flexible arms C, for the purpose of retaining it in position after it has been inserted into the teat of t h e animal. The parts which grip the teat may be ribbed on their inner surfaces.
Patent GB-189706977-A (GB)
Title: Improvements in Sun-hats, Hoods, Bonnets, or like Head Coverings.
Inventor: MASON JOHN FRANCIS
Filed: 1897-03-17
Granted: 1898-01-29
Abstract: 6977. Mason, J. F. March 17. Bonnets; hoods.-Sun bonnets, hoods, and the like are constructed so that they can be laid out flat for washing and ironing purposes. The bonnet consists, as shown in inside view in Fig. 2, of a semicircular piece A with suitable ornamental attachments and with two draw-strings G by which the bonnet is drawn up into the shape required.
Patent GB-189720508-A (GB)
Title: Improvements in Corset Eyes and in Blanking and Studding Machines adapted for Producing same.
Inventor: JUSTICE PHILIP MIDDLETON
Filed: 1897-09-07
Granted: 1898-01-01
Abstract: 20,508. Justice, P. M., [Warner Bros. Co.]. Sept. 7. Making dress fastenings.-Stud and eye or slot fastenings are formed with the slotted plates provided with the two rivet pins secured to the plates. Fig. 1 shows the steps of the process, Fig. 2 a view of the finished article, and Fig. 11 a partial vertical section of one form of the apparatus. A metal strip X is fed in the direction of the arrow 1a, and is brought under a double punch 4, the rear portion piercing the holes x, x<1> while the forward portion cuts out the blank Y and carries it downward (arrow 2a) to a slide C. The slide is then moved transversely to the position shown in Fig. 11. The wires a to form the rivets are intermittently fed by grooved rollers 17, and lengths are cut off by sliding cutting or jaw plates. The cut-off portions are moved by the jaws in the direction of arrows 6a, and are brought under the blanks Y so as to be received in the holes x<1>, where they are riveted by the punch F, the upper faces of the sliding jaws being countersunk so as to produce riveting on both faces of the plate Y simultaneously. The various motions required for the operating parts are obtained from a main shaft provided with the necessary cams and eccentrics. The various steps are carried out in the abovedescribed order, or the machine may be so modified that the various steps are performed in a different order. In the modified form of apparatus, the holes are first punched transversely in the strip, the rivet holes being countersunk so as to allow the riveting to be flush with the surface of the strip. The wires are fed into position and are cut off and riveted before the strip is passed under the die that cuts the plate out of the strip.
Patent GB-189720781-A (GB)
Title: Improvements in the Generation and Distribution of Electricity by Means of Alternating Currents, and Appliances connected therewith.
Inventor: ATKINSON LLEWELYN BIRCHALL
Filed: 1897-09-09
Granted: 1898-06-11
Abstract: 20,781. Atkinson, L. B. Sept. 9. Drawings to Specification. Distributing; regulating.-In alternating-current systems, an induction motor is arranged in the circuit and is driven, in some cases, above synchronism to serve as generator, the alternator being used only to impress the required number of periods. In other arrangements the induction machine may be used only to supply the idle or lagging current. The induction machine may be arranged at the generating-station at a distance, and may be driven separately or by another induction motor, suitable gearing being used. The machine may be connected to the circuits directly, or through transformers, and be used with single- or poly-phase currents. Regulation is effected by inserting suitable resistance or capacity, or by varying the relative speeds, or the relative number of poles on the machines.
Patent GB-189722309-A (GB)
Title: An Improved Method of Imparting Motion to the Screw of a Vessel, and Apparatus therefor.
Inventor: SIDEBOTTOM HENRY
Filed: 1897-09-29
Granted: 1897-11-06
Abstract: 22,309. Sidebottom, H. Sept. 29. Screw propellers. -Relates to means for driving a screw propeller. Passages or conduits f formed in the blades b communicate with a central pressure chamber c in the boss ; water is forced outwards through these passages after the manner of a Barker's mill. The propeller may be driven i n either direction by providing two sets of passages f, h, and closing one set or the other by a piston valve i operated by a rod k.
Patent GB-189722643-A (GB)
Title: Improvements in Water Tube Boilers for Generating Steam.
Inventor: OWEN JOHN HENRY
Filed: 1897-10-02
Granted: 1898-09-17
Abstract: 22,643. Owen, J. H. Oct. 2. Steam-generator furnaces.-Relates to water-tube boilers specially suitable for marine use. Sets of headers of rectangular section constitute the walls of the combustion chamber. The headers B, forming the top thereof, are connected to the headers F by the headers Land E forming the sides and front respectively, and to the headers K by the tubes N which constitute the chief heating-surface. The headers F and K, which form the bottom of the combustion chamber, are also connected to the mud drums J and 0. The steam drum A and the large downcomers Q, R connecting it to the mud drums are placed outside the combustion chamber.
Patent GB-189722806-A (GB)
Title: Improvements in and relating to Alternating Current Dynamo Electric Generators.
Inventor: BRADLEY CHARLES SCHENCK
Filed: 1897-10-05
Granted: 1897-11-13
Abstract: 22,806. Bradley, C. S. Oct. 5. Dynamos, alternating-current; motors, controlling.-The object is to enable currents of variable frequency to be produced by a machine driven by a prime mover running at practically constant speed, more particularly for supplying induction motors which require a low frequency and electromotive force in starting and increasing frequency and electromotive force as the speed rises. Fig. 1 shows diagrammatically the arrangement employed for producing three-phase currents of variable frequency, together with a number of induction motors 1, 2, and 3 supplied by such currents. The generator consists of a fixed armature element 4, with an ordinary three-phase winding, and a rotary field element 5 supplied with three-phase currents by an exciter 7, the connections with the exciter being so arranged that the direction of polar travel of the rotary field is opposite to the bodily movement of the core. The resultant velocity of the magnetic field is adjusted by varying the speed of the exciter ; at the same time the product of capacity and inductance in the exciter circuit is varied so as to produce electrical resonance therein. This is effected by driving the exciter shaft through variable-speed gear actuated by a lever 14, which simultaneously varies the capacity of the condensers 13, 13<a>, and 13<b>. The invention is also shown applied to a quarter-phase current generator.
Patent GB-189723240-A (GB)
Title: Improvements in Jugs or the like having Hinged Lids.
Inventor: THOMPSON WILLIAM PHILLIPS
Filed: 1897-10-09
Granted: 1897-12-11
Abstract: 23,240. Thompson, W. P., [Heinemann, A.]. Oct. 9. Jugs.-The lid b of a beer jug &c. is provided with a bar c, which is bent to form a thumb-piece e and is furnished with depending wings d, the wings being pivoted to the projection g on the handle f by means of the screw spindle h. The spindle is made thicker at the centre than at the ends, to minimize any lateral pressure when opening the lid.
Patent GB-189723326-A (GB)
Inventor: PENDLETON GURDON
Filed: 1897-10-11
Granted: 1897-12-04
Abstract: 23,326. Pendleton, G., and Mitchill, C. S. Oct. 11. Bottles etc.; stoppers.-Relates to bottles, jars, &c. for containing fruit, preserves, paint, &c. The neck of the vessel is formed with an external shoulder to receive the packing-washer B', and is screw-threaded at C to receive the screw cap E. The glass or other closing-plate is revolubly secured within the cap E, the rim G of the plate bearing on the washer B<1>. A bail M, pivoted to the cap, serves as a handle for carrying, or for screwing up or unscrewing the cap. The cap E may also be used without the plate.
Patent GB-189724146-A (GB)
Title: An Improved Fountain Pen.
Inventor: STEPHENS HERBERT HIPPISLEY
Filed: 1897-10-19
Granted: 1898-08-13
Abstract: 24,146. Stephens, H. H. Oct. 19. Pens and penholders, reservoir. The nib a is covered on its upper surface by a curved ink supplying and retaining shield b, provided with a central groove b<1>. The outer end of the holder is closed by the plug f having an air inlet g; or a separate tube h may be provided.
Patent GB-189726904-A (GB)
Title: Improvements in Receptacles for Containing or Storing Butter and the like.
Inventor: BRAASCH BERNHARD HINRICH FRIED
Filed: 1897-11-17
Granted: 1898-10-01
Abstract: 26,904. Braasch, B. H. F., and Ziete, E. Nov. 17. Refrigerators. - Casks a for use in shops &c. for keeping butter and butter substitutes &c. are provided with an inner receptacle b, which alone receives the butter &c. and is pref erably surrounded by an ice or cooling chamber d, which may be provided with an annular ring or lid a<2>.
Patent GB-189802970-A (GB)
Title: Improvements in or relating to Apparatus for Conditioning and Drying Grain, Berries, Sugar, Seeds, Crystals and Granular or Pulverulent Material generally.
Inventor: MALLINSON CHARLES
Filed: 1898-02-05
Granted: 1898-10-15
Abstract: 2970. Mallinson, C. Feb. 5. Conditioning grain.-Relates to apparatus for use in conditioning wheat or other grain or for drying crystals, sugar, berries, and other granular materials. The apparatus consists of two vertical columns A and B, in which are arranged a series of parallel steam pipes D communicating with a chest E fed by a steam pipe E<1>. The pipes D in the lower end of the column B are reduced in diameter or discontinued so that the material leaving the column B is cooled. For the same purpose, a cold air passage M with inlets into the column B is arranged round the bottom of the column. The columns are provided with baffle-plates, of which two arrangements are described, and with inlet holes K from a hot-air chest C heated by the steam chest N and also with outlet holes F into a trunk G connected to a fan G<1>. The grain is first fed from the hopper O<1> through the column A, and is then carried by an elevator to the hopper 0 and passed through the column B. The hoppers 0 and O<1> are provided with feed - regulating devices.
Patent GB-189803104-A (GB)
Title: A New or Improved Device for Catching Flies.
Inventor: THUM HUGO
Filed: 1898-02-07
Granted: 1898-04-09
Abstract: 3104. Thum, H. Feb. 7. Traps for flies. Relates to a device for catching flies by means of a cord coated with sticky material. A glass vial A with a wide neck is filled with sufficient sticky material to coat the cord D as far as the point J. The upper part B of the cord D is not coated, but is passed through a hole in the cork C and fixed therein by means of a seal F of such consistency that it is easily removed on drawing the cord through the hole in the cork C by means of the loop H. The hole in the cork C prevents an undue amount of the sticky material from adhering to the cord. A knot is tied in the end of the cord to prevent it from being drawn through the hole in the cork.
Patent GB-189804723-A (GB)
Title: Improvements in or relating to the Manufacture of Moulds and Castings.
Inventor: BOULT ALFRED JULIUS
Filed: 1898-02-25
Granted: 1898-04-23
Abstract: 4723. Boult, A. J., [Franco American Casting Co.]. Feb. 25. Casting and moulding.-Relates to a method and apparatus for producing sharp and well-finished ornamental and like castings in bronze, brass s, silver, or gold. Elastic patterns of vulcanized rubber &c. are preferably used. The moulds are made of plaster consisting preferably of one part of fine asbestos pulp and two parts of plaster of Paris. When the mould is set, the pattern is removed and the mould dried in an oven at about 150‹ C. and then heated to about 400‹ C. for 4 or 5 hours to remove sulphuretted hydrogen. The finished mould with the necessary gits &c. is placed in the casting-machine, Fig. 2, the parts of the mould being held securely together by clamping- screws G. The molten metal is poured into a cylindrical pot J, from which it is forced into the mould through a gate S by a ram K. which is lowered by hand by a rack and pinion. The pot J is made in two parts, of which the outer one may be removed by turning it round a hinge ; it is also provided with a non-conducting lining T, preferably of asbestos sheet felt, about 1 mm. thick, made up on a former to the required shape and placed in the pot prior to filling. The lining prevents the metal from flowing into the mould till the lowering of the ram K breaks through the part covering the gate S.
Patent GB-189808943-A (GB)
Title: Improvements in Valve Gear for Steam Engines.
Inventor: BOSSHARDT FERDINAND
Filed: 1898-04-18
Granted: 1898-08-27
Abstract: 8943. Bosshardt, F., [Frikart, J. R.]. April 18. Valve gear.- Consists of trip or releasing gear for operating valves of the Corliss type. The lower arm B, continuously reciprocated by the actuating - eccentric, is connected to the arm F on the valve spindle by toggle links. When the latter are in a straight line and the lever B moving from left to right, the valve is opened in opposition to the downward pull of the dash-pot rod. The point of cutoff is determined by the toggle links being pushed out of the straight line by a collar L on the stud I coming into contact with an abutment M. The latter is carried by an arm which can be adjusted angularly by the engine governor and the point of cut-off thereby varied.
Patent GB-189809986-A (GB)
Title: An Improved Combined Trousers Presser and Stretcher.
Inventor: STEGGALL WILLIAM FREDERIC
Filed: 1898-04-30
Granted: 1898-09-03
Abstract: 9986. Steggall, W. F. April 30. Trouser presses; trouser stretchers.-Relates to an appliance for pressing and stretching trousers. It consists of two plates o, a' coupled together near each end by cross-strips b, b<1> and vertical side bolts c, c<1> provided with adjusting-nuts c<2>. To the forward bolts is attached a lazy-tongs arrangement e, e<1> carrying presser-bars f, f at their outer ends. The trousers are placed between the plates a, a' with one end lying between the bars f, f<1> so that, when the nuts c<2> are screwed down, the lazy-tongs arrangement is operated, and the trousers are simultaneously stretched and pressed. The bars f, f<1> are adjustable in position for different thicknesses of trousers, and the plates a, a<1> are hollowed out on their meeting faces to provide a space for the trouser seams.
Patent GB-189811431-A (GB)
Title: Improvements in Means for Reducing or Preventing Vibration in Wheeled Vehicles.
Inventor: DUNLOP HENRY WALLACE DOVETON
Filed: 1898-05-19
Granted: 1898-06-25
Abstract: 11,431. Dunlop, H. W. D. May 19. Springs, bearing; vibration, preventing.-The inflated tube a is placed in the blocks b, c clipped respectively to the underframe and body of the vehicle. The blocks have flexible strips d, which are connected together by pins d<2>.
Patent GB-189817459-A (GB)
Title: A Novel or Improved Device for use in Raising Bricks, Tiles, and the like during Building Operations.
Inventor: EDWARDS GEORGE PHOENIX
Filed: 1898-08-13
Granted: 1899-06-24
Abstract: 17,459. Edwards, G. P., [known as Phoenix, G.]. Aug. 13. Skips.-For lifting bricks and tiles during building operations, a skeleton box for the reception of the bricks is made up of metal strips a<1>, b<1>, bent into a rectangular shape and riveted together. One side b<2> of the box is hinged to allow filling. To close the box when full, the hinged and slotted flap b<3> is pushed over the lugs a<3> and the lifting hook f inserted in the hole d. The flap b<3> may be extended across the box to engage with an upright on the side b<1>.
Patent GB-189819630-A (GB)
Title: Improved Apparatus for Medical Gymnastic Exercise.
Inventor: HERZ MAX
Filed: 1898-09-15
Granted: 1899-07-29
Abstract: 19,630. Herz, M. Sept. 15. Gymnastic apparatus. - Relates to medical gymnastic apparatus for exercising the hand, wrist, and arm. The heavy wheel a is pivoted to a stand and provided with a handle b<1>, so that it may be rotated through a considerable angle, say up to 300‹. The motion is limited by a spring d attached by a link c<1> to a crank c on the spindle of the wheel. A spiral spring or elastic cords may replace the spring d. Additional weights a<1> may be attached as shown.
Patent GB-189819946-A (GB)
Title: New or Improved Device for Carrying or Transporting Luggage and the like.
Inventor: HART JAMES TYETH
Filed: 1898-09-20
Granted: 1899-04-22
Abstract: 19,946. Hart, J. T. Sept. 20. Handbarrows; hand-trucks.-Figs. 1 and 3 show a flexible frame for carrying heavy luggage. Parallel strips a of cord, leather, webbing, &c. riveted to a rectangular distance-plate b, which may also be a basket for carrying light parcels or a chair for invalids and other persons, are secured to slotted handle-bars e by wedges, and in some cases braced by stays, not shown. The plate b carries bracket d to which castors h may be attached.
Patent GB-189821948-A (GB)
Title: Improvements in Separating Metallic from Rocky Constituents of Ores and Apparatus therefor.
Inventor: ELMORE FRANCIS EDWARD
Filed: 1898-10-18
Granted: 1900-01-18
Abstract: 21,948. Elmore, F. E. Oct. 18. Treating ores; washing ores.-Consists in separating the metallic from the rocky constituents of pulverized ores by mixing with water and then bringing the mixture into contact with thick oil. The oil entraps the metallic constituents, which are afterwards separated, and the rocky constituents pass away with the water. The Figure shows a form of the apparatus. The mixture of pulverized ore and water, supplied by a pipe, and the oil, supplied by the pipe b, flow into a rotating drum c provided with helical ribs d which extend from end to end. The spaces between these ribs are divided into cells by equidistant blades. The ore, oil, &c. are discharged from the end of the drum into a vessel e, in which the rocky constituents subside, while the oil with the metallic constituents floats above. The lowest layer is drawn away as tailings and passes through a pipe f to another drum g, and the process is repeated until the whole of the mineral constituents are separated. The oil and the contained mineral matter are led by pipes l to a rotating drum m containing water and subjected to centrifugal action. The mineral matter passes into the water, and the oil flows out into the casing h, and thence is pumped up through a pipe g to a cistern, preferably partially exhausted of air, and may be used over again. Instead of the separation by centrifugal action, the oil may be thinned by heating or mingling it with solvents such as benzoline, and afterwards left for subsidence or passed through a filter press,
Patent GB-189906194-A (GB)
Title: A New or Improved Combined Process for Working Designs in or upon Plate, Sheet, or other Flat Glass.
Filed: 1899-03-22
Granted: 1900-03-03
Abstract: 6194. Gateshead Stained Glass Co. and Snee, J. E. March 22. Drawings to Specification. Ornamenting; stained glass.-Relates to the production of ornamental and stained plates or sheets of glass, applicable for windows, panels, or other flat decorative glass transparencies. The invention consists in cutting, grinding, pressing, or moulding the desired pattern on one or both sides of the sheet, polishing, frosting, or buffing any desired parts, and finally applying colours which are fixed by burning or fusing.
Patent GB-189906807-A (GB)
Title: Improvements in and relating to the Frames of Velocipedes.
Inventor: MORRIS GEORGE LEONARD
Filed: 1899-03-29
Granted: 1900-02-03
Abstract: 6807. Morris, G. L. March 29. Frames.-The invention is described as applied to a bicycle, but is stated to be applicable with slight modification to tricycles, tandems, &c. The frame is construoted of tubes A, B, C, D, E, F as shown, and one or more of the additional stays G, H, J shown in dotted lines are sometimes added.