baber/WOPTO huggingface dataset:
Patent NZ-336046-A (NZ)
Title: Serine protease inhibitors containing substituted oxadiazole, thiadiazole and triazole peptide derivatives
Inventor: GYORKOS ALBERT
IPC: A61P43/00
Filed: 1997-12-05
Abstract: The pyrrole derivative has the formula (I) wherein: X is O and Y is N; R1 is isopropyl, n-butyl, tert-butyl, or is alkyl substituted with one or more carboxyl, carboalkoxy, amino, alkylamino or dialkylamino groups or is alkyl fused aryl, alkyl fused arylcycloalkyl, alkyl(aryl)2 or a,a-dialkyl-arylalkyl optionally comprising 1-4 heteroatoms selected from O, S and N, and optionally substituted with halo, cyano, nitro, hydroxyl, haloalkyl, amino, aminoalkyl, dialkylamino, alkyl, alkenyl, alkylenedioxy, alkynyl, alkoxy, haloalkoxy, carboxyl, carboalkoxy, alkylcarboxamide, aryl, -O-aryl, arylcarboxamide, alkylthio or haloalkylthio or R1 is aryl or arylalkyl substituted with alkyl, amino, alkylamino, dialkylamino, optionally substituted aryl or aryloxy or is aryl or arylalkyl substituted with two more halo, cyano, nitro, hydroxyl, haloalkyl, amino, amino alkyl, dialkylamino, alkyl, alkenyl, alkylenedioxy, alkynyl, alkoxy, haloalkoxy, carboxyl, carboalkoxy, alkylcarboxamide, alkylthio, haloalkylthio, arylcarboxamide or optionally substituted aryl or -O-aryl or R1 is aryl or arylalkyl comprising one or more heteroatoms selected from O, S and N or cycloalkyl or alkylcycloalkyl optionally comprising one or more heteroatoms selected from O, S and N;  R2 and R3 are independently or together H, alkyl or alkenyl optionally substituted with 1-3 halo, hydroxyl, thio, alkylthio, amino, alkylamino, dialkylamino, alkylguanidinyl, dialkylguanidinyl, guanidinyl, or amidylguanidine or are -RCOR', RCOOR', -RNR'R"R" or -RC(O)NR'R"; R is alkyl or alkenyl; R', R" and R" are independently H, alkyl, alkenyl, cycloalkyl or aryl or are cycloalkyl, alkylcycloalkyl, alkenylcycloalkyl, alkyloxyaryl, alkylthioaryl, alkylaminoaryl, aryl, arylalkyl or (cs-cl2)arylalkenyl optionally comprising 1-4 heteroatoms selected from N, O and S, and optionally substituted with halo, cyano, keto, nitro, hydroxyl, haloalkyl, amino, aminoalkyl, dialkylamino, amidine, alkylamidine, dialkylamidine, alkyl, alkenyl, alkylenedioxy, alkynyl, alkoxy, haloalkoxy, carboxyl, carboalkoxy, alkylcarboxamide, aryl, -O-aryl, arylcarboxamide, alkylthio or haloalkylthio;  A is a direct bond, -NHC(O) or is proline, isoleucine, cyclohexylalanine, optionally substituted cysteine, phenylalanine, homophenylalanine, dehydrophenylalanine, indoline-2-carboxylic acid, optionally substituted  tetrahydrosioquinoline-2-carboxylic acid, tryptophan, tyrosine, serine, threonine, histidine, methionine, valine, norvaline, norleucine, octahydroindole-2-carboxylic acid, asparagine, glutamine, ornithine or lysine  and R4 is benzyl.  A pharmaceutical composition thereof is useful for inhibiting serine proteases.
Patent NZ-502828-A (NZ)
Title: Combined bone vibration and air conduction transducer in telephone receiver
Inventor: KANG KYEONG OK
IPC: H04M1/03
Filed: 1997-11-04
Abstract: A telephone receiver includes a transducer, which receives the electrical signals and simultaneously converts the electrical signals into audible signals to be heard via the human ear and vibration signals for inducing bone conduction hearing in humans.  The transducer includes a magnet structure 22, 23, 24 with a voice coil 25a mounted on a bobbin 25, the movement of the voice coil in the yoke gap causing movement of the audio diaphragm 26 and the mechanical diaphragm 27 attached to the vibration transmitter 30.
Patent NZ-504922-A (NZ)
Title: Light fitting with reflector on one side and perforated heat shield on other side
Inventor: CRONK PAUL ANDREW
IPC: F21V11/00
Filed: 2000-06-02
Abstract: The light fitting has reflector 2 on one side of  lamp receiving fixture 18 and perforated heat shield 17 located on the opposite side of fixture 18. Shield 18 is angled relative to the fixture. Typically the heat shield may be inverted V-shaped or single ridge and double-hipped shaped.
Patent NZ-506144-A (NZ)
Title: 6-(substituted-phenyl)-pyridazin-3-one derivatives and pharmaceuticals thereof; used as inhibitors of interleukin-1-beta production
Inventor: YOSHIZAKI HIDEO
IPC: A61K31/50
Filed: 1999-02-26
Abstract: The pyridazine derivative has the formula (1), wherein: R1 is alkoxyl, alkylthio or halogen; R2 is H, alkoxyl, alkylthio or halogen; R3 is an alkyl or alkenyl, optionally substituted by hydroxyl, halogen, cyano, cycloalkyl, optionally substituted aromatic or an optionally substituted carbamoyl; R4 is carboxyl, alkoxycarbonyl, optionally substituted carbamoyl, optionally substituted thiocarbamoyl, optionally substituted amino, or optionally substituted ureido; The dashed line indicates that the carbon-carbon double bond between the 4-position and the 5-position is a single bond or a double bond. Salt of the pyridazine compound of formula (1) are also described. Also described are pharmaceutical compositions that comprise the pyridazine compounds of formula (1) or salts thereof. The pyridazine compounds of formula (1) are used for the treatment of diseases caused by stimulation of interleukin 1-b production.
Patent NZ-508519-A (NZ)
Title: Preparation of human papillomavirus E1 having helicase activity and method therefor
Inventor: PELLETIER ALEX
IPC: C12N9/90
Filed: 1999-04-28
Abstract: The present invention relates to a method for isolating cloned papillomavirus E1 protein from a eukaryotic expression system having demonstrable and reproducible viral helicase activity and preparation containing essentially pure E1 protein. The invention further relates to the use of this E1 protein preparation in a screening assay for identifying antiviral agents. More particularly a high throughput assay to screen for agents capable of inhibiting HPV DNA replication. The assay is based on measuring the effect of antiviral agents on the activity of the E1 protein and more specifically on its helicase activity.
Patent NZ-513716-A (NZ)
Title: New uses of fluorinated triazoles
Inventor: SCHMUTZ MARKUS
IPC: A61K31/4192
Filed: 2000-02-28
Abstract: A triazole of formula (I) where Ph is optionally halogen substituted o-fluorinated phenyl, R1 is H, carbamoyl, N-alkanoyl carbamoyl, N,N-di-alkyl carbamoyl and R2 is carbamoyl, N-alkanoyl carbamoyl, N,N-di-alkyl carbamoyl is used in the manufacture of a medicament to treat neuropathic pain and affective and attention disorders.
Patent NZ-517011-A (NZ)
Title: Cell adhesion inhibitors
Inventor: LEE WEN-CHERNG
IPC: A61P19/02
Filed: 2000-08-14
Abstract: A compound or a pharmaceutically acceptable salt thereof has the formula (I) R3-L-L'-R1 wherein: R1 is H, alkyl, alkenyl, alkynyl, Cy, Cy-alkyl, Cy-alkenyl or Cy-alkynyl; Cy is cycloalkyl, cycloalkenyl, heterocyclyl, aryl, or heteroaryl L' is an optionally substituted hydrocarbon linker moiety having 1-5 carbon chain atoms which is interrupted by, or terminally attached to, one or more of -C(O)-, -O-C(O)-, - C(O)-O-, -C(O)-NRc-, -NRc-C(O)-, NRc-C(O)-NRd-, -NRc-C(O)-O- , -O-C(O)-NRc-, -S(O)m-, -SO2-NRc-, -NRc-SO2-, -NRc- C(NR111)-, -O-, -NRc- or Cy; L is a an optionally substituted hydrocarbon linker moiety having 1-14 carbon chain atoms which y interrupted by, or terminally attached to, one or more -C(O)-, -O-C(O)-, -C(O)- O-, -C(O)-NRc-, -NRc-C(O)-, NRc-C(O)-NRd-, -NRc-C(O)-O-, -O- C(O)-NRc-, -S(O)m-, -SO2-NRc-, -NRc-SO2-, -O-, -NRc- or Cy and R3 is alkyl, alkenyl, alkynyl, cycloalkyl, aryl-fused cycloalkyl, cycloalkenyl, aryl, aralkyl, aryl-substituted alkenyl or alkynyl, cycloalkyl-substituted alkyl, cycloalkenyl-substituted cycloalkyl, biaryl, alkenoxy, alkynoxy, aralkoxy, aryl-substituted alkenoxy or alkynoxy, alkylamino, alkenylamino or alkynylamino, aryl-substituted alkylamino, aryl-substituted alkenylamino or alkynylamino, aryloxy, arylamino, heterocyclyl, heterocyclyl-substituted alkyl, heterocyclyl-substituted amino, carboxyalkyl substituted aralkyl, or oxocarbocyclylfused aryl or R4-Y5- N(R5)-C(H)(R6)-; Y5 is -CO-, -O-CO-, -SO2- or -PO2; R111, R4 to R6 are as defined in the specification; provided that when L is saturated and has 1-4 carbon chain atoms, (i) L must contain a heteroatom selected from O, S, and N; or (ii) R3 must contain the moiety o-methylphenyl-ureido-phenyl- CH2- or (iii) R1 must contain only one Cy group. The compounds are useful for inhibiting VLA-4- dependent cell adhesion.
Patent NZ-517284-A (NZ)
Title: Devices and methods of vertebral disc augmentation
Inventor: LAMBRECHT GREG H
IPC: A61F2/46
Filed: 2000-08-18
Abstract: A disk herniation constraining device for implantation into  a  vertebral  disk can include a  support  member  for support  of  a  herniated portion of  a  disk.  The  support member  can  be  connected  to an anchor.  The  constraining device  can  include the insertion of augmentation  material within  the disk. A defect in the annulus of a disk  can  be closed  using  a prosthesis such as a barrier.  The  barrier can  be  placed between the annulus and the nucleus  of  the disk.  The  barrier can include a sealant and  an  enlarger. The  barrier can be implanted into the disk using a delivery cannule,  an  advancer and at least one control filament  to control  the positioning of the barrier over the  defect.  A stiffening  element can be included within  the  barrier  to impart stiffness to the barrier.
Patent NZ-526658-A (NZ)
Title: Safety injection device for a liquid or semi-solid composition
Inventor: CHERIF-CHEIKH ROLAND
IPC: A61M5/24
Filed: 2002-04-09
Abstract: Disclosed is an injection device including a housing, the housing having proximal and distal ends and designed to contain a liquid or semi-solid drug composition; a hollow needle, the needle affixed to the distal end of the housing and extending longitudinally within the housing; a plunger, the plunger arranged to slide within the proximal end of the housing; and a hollow sleeve, the hollow sleeve arranged to cover the needle prior to injection and to retract into the housing during injection ; wherein the device is designed such that when the sleeve is pressed against the subject, the sleeve retracts into the housing and the drug composition is delivered through the needle and into the subject.
Patent NZ-527642-A (NZ)
Title: Use of fusion proteins whose N-terminal part is a hirudin derivative for the production of recombinant proteins via secretion by yeasts
Inventor: HABERMANN PAUL
IPC: C07K19/00
Filed: 2002-02-08
Abstract: The description relates to an expression cassette of the form Px-Sx-Bn-(ZR)-Hir (AsmR)-protein (Y) - T, where Px is any promoter DNA sequence, selected in such a way that optimal yields of the protein of interest become achievable; Sx is any DNA encoding a signal sequence or leader sequence which allows optimal yields; Bn is 1-15 amino acid codons or a chemical bond; Z is the codon of a amino acid selected from the group comprising Lys and Arg; R is an Arg codon or a chemical bond; Asm is a chemical bond or m amino aid codons, where m= 1-10; Hir is a DNA sequence coding for hirudin or a hirudin derivative; protein Y is a DNA sequence encoding any protein that can be produced in and secreted by yeast; T is an untranslated DNA sequence which is advantageous to the expression.
Patent NZ-533673-A (NZ)
Title: Information resource taxonomy
Inventor: RYAN SIMON DAVID
IPC: G06F40/00
Filed: 2002-12-18
Abstract: An information resource taxonomy system includes: a data collector for collecting information resources from a communications network and a taxonomy generator for generating clusters of the resource based on similarity values for the respective grouping of the resources and for iteratively generating sub clusters of the clusters based on similarity values for the respective grouping of the resources within each of the clusters and within each of the sub clusters providing a taxonomy for the resources as a hierarchy of resource clusters. The number of resource clusters is determined by the content of the resource. The system also includes an editor for editing the taxonomy and a renderer for generating linked document data for displaying the hierarchy. A parallel cluster search system can also be included to evaluate clusters in parallel. The system also includes a parallel classifier for classifying further collected resources.
Patent NZ-534346-A (NZ)
Title: System and method for providing messages on a wireless device connecting to an application server
Inventor: MINEAR BRIAN
IPC: H04W4/24
Filed: 2003-01-31
Abstract: While a wireless device is waiting for download across the network of application data from an application server, a message such as an advertisement message is transmitted to the wireless device via the network and displayed on the graphic display of the device.
Patent NZ-536507-A (NZ)
Title: Use of eicosapentaenoic acid or docosahexaenoic acid or fish oil for prevention of cerebral damage in patients having symptoms of atherosclerosis or arteries supplying the brain i.e stroke
Inventor: CALDER PHILIP
IPC: A61P7/00
Filed: 2003-05-02
Abstract: Disclosed is the use of the n-3 PUFA EPA and DHA in the preparation of an oral medicament for preventing cerebral damage in patients having symptoms of atherosclerosis of arteries supplying the brain.
Patent NZ-538783-A (NZ)
Title: Water filling system for a humidifier
Inventor: LEVINE WALTER
IPC: A61J1/10
Filed: 2003-09-18
Abstract: A humidifier apparatus (10) for operating at an air pressure is disclosed for use with a respiratory therapy breathing apparatus that provides a breathable gas supply to patients requiring higher concentrations of liquid vapour and gas pressure. The humidifier apparatus includes a feed liquid supply bag (20) in fluid communication with a humidifier cartridge (14) via a conduit (26). The conduit enables air to flow there through to equalize air pressure between the humidifier cartridge and the feed liquid supply bag in response to liquid (18) being supplied to the humidifier cartridge.
Patent NZ-539781-A (NZ)
Title: A process for the manufacture of sulphur-containing ammonium phosphate fertilizers
Inventor: KEENAN KENNETH WILLIAM
IPC: C05G3/00
Filed: 2003-11-12
Abstract: Disclosed is a process for the manufacture of sulphur-containing fertilizers, the process comprising the steps of: (a) bringing a liquid phase comprising elemental sulphur into contact with ammonia, phosphoric acid and water in a reactor unit to obtain an ammonium phosphate mixture, wherein the elemental sulphur is introduced into the reactor unit substantially at the same time as the other reactants; and (b) introducing the mixture obtained in step (a) into a granulator unit to obtain granules.
Patent NZ-540772-A (NZ)
Title: Automated pallet inspection and repair using robot and three dimensional data map of pallet surface
Inventor: LUCAS MICHAEL DAVID
IPC: G01M99/00
Filed: 2003-12-10
Abstract: An automatic pallet inspection cell (10) comprises one or two multi axis robot arms (14, 15) which terminate in either internal or exterior pallet grippers. The robots are used to transport a gripped pallet (12) through an automated inspection station (16) which compiles a three dimensional data map of a pallet surface. A processor interprets the map and producing a recipe for the robot or robots. One or more stations (17, 18, 19) conduct pallet repair operations that are specified by the recipe.
Patent NZ-540923-A (NZ)
Title: Pyrazolo[3,4-b]pyridine compounds, and their use as phosphodiesterase inhibitors
Inventor: ALLEN DAVID GEORGE
IPC: A61P37/00
Filed: 2003-12-19
Abstract: The present disclosure relates to pyrazolo[3,4-b]pyridine compounds of formula (I), wherein the variables shown in formula (I) are as defined in the specification, processes for their preparation, intermediates usable in these processes, and pharmaceutical compositions containing the compounds. The disclosure also relates to the use of pyrazolopyridine compounds in therapy , for example as inhibitors of phosphodiesterases (PDE), in particular PDE4 inhibitors, and/or for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), atopic dermatitis, urticaria, allergic conjunctivitis, vernal conjunctivitis, eosinophilic granuloma, psoriasis, septic shock, ulcerative colitis, Crohn's disease, reperfusion injury of the myocardium and brain, chronic glomerulonephritis, endotoxic shock, asthma, rheumatoid arthritis, allergic rhinitis or adult respiratory distress syndrome in a mammal.
Patent NZ-541887-A (NZ)
Title: Oils enriched with diacylglycerols and phytosterol esters for use in the reduction of cholesterol and triglycerides
Inventor: PLATT DORIT
IPC: A23L1/30
Filed: 2004-02-10
Abstract: Disclosed is the use of a composition comprising a combination of diacylglycerol(s) (DAG), mainly 1,3-diacylglycerol(s), and phytosterol and/or phytostanol ester(s) (PSE) dissolved or dispersed in edible oil and/or edible fat, particularly olive, canola and fish oil, in the manufacture of nutritional supplements and orally administrable pharmaceutical preparations which are capable of reducing blood levels of both cholesterol and triglycerides and/or for lowering serum, serum LDL and macrophage oxidation levels, inhibiting the formation of foam cells and/or preventing the deleterious effects generated by lipid-induced oxidative stress. Also disclosed is the use of the composition and pharmaceutical preparations thereof for the treatment and prevention of conditions related to atherosclerosis, such as cardiovascular disease (CVD), coronary heart disease (CHD) and diabetes mellitus.
Patent NZ-546899-A (NZ)
Title: Improving post-thaw survival of cryopreserved biological material by hydrostatic pressure challenge
Inventor: PRIBENSZKY CSABA
IPC: A01N1/02
Filed: 2004-09-08
Abstract: The present disclosure relates to a method for improving post-thaw survival of cryopreserved biological material including oocytes, sperms, zygotes, blastocysts and stem cells. The method comprises of applying hydrostatic pressure to said biological material; keeping the said biological material at the hydrostatic pressure for a predetermined time period; releasing the hydrostatic pressure; and freezing the said biological material using any protocol applicable thereto. Further disclosed is the use of a pressurizing device for the pretreatment of a biological material that is to be cryopreserved, as well as to a pressurizing device for the pretreatment of a biological material that is to be cryopreserved, said device comprising a pressure chamber for receiving biological material, means to produce said pressure, and means to maintain said pressure in said chamber.
Patent NZ-549755-A (NZ)
Title: Benzimidazole derivative and use as AII receptor antagonist
Inventor: KUROITA TAKANOBU
IPC: A61P9/00
Filed: 2005-02-23
Abstract: Disclosed is a compound of formula (I), where R1 is a dioxolane derivative, and the other substituents are disclosed in the specification, or a salt thereof. Also disclosed is a process for producing the compound. Also disclosed is the use of the compound to treat circulatory diseases, where insulin resistance is involved, or nerve degeneration diseases.
Patent NZ-551121-A (NZ)
Title: Carton and carton blank with reinforced handle structure
Inventor: BLIN PATRICK
IPC: B65D71/38
Filed: 2005-04-08
Abstract: An open top carton 30 with at least one three ply reinforced handle and a separate top closure 22, where both the carton 30 and the top closure 22 are formed from separate blanks and where the first ply of the handle is provided by the carton, the second ply of the handle is provided by the closure and the third ply of the handle is provided either by the carton 30 or the closure 22. The first ply has a first hand opening, the second ply a second hand opening and both hand openings are aligned to provide a single hand opening.
Patent NZ-561608-A (NZ)
Title: System and method for extracting and conveying modulated AC signal information
Inventor: HORNSBY JAMES RUSSELL
IPC: H05B44/00
Filed: 2006-03-30
Abstract: An apparatus for extracting and interpreting information from an AC signal comprises: a signal input for receiving at least one AC signal; an operational amplifier for receiving and outputting the AC signal; a dual diode configured to receive the AC signal and split the AC signal into two separate paths, a comparator for comparing amplitudes of the AC signal from the baseline path and the AC signal from the filtering path; and a microprocessor for receiving the comparator output and controlling a display. The display is configured to generate a visual indicia responsive to the comparator output. The two separate paths including a baseline path and a filtering path. The AC signal passes through the baseline path remains substantially unchanged and the AC signal passing through the filtering path passes through a Iow-pass filter. The comparator yields a comparator output that is a binary state.
Patent NZ-573156-A (NZ)
Title: Induction and fuel delivery system for piston engine using a cyclone to generate vortex mixing of fuel and air mixture before entering the cylinder
Inventor: JOHNSON DAVID LITTLEWOOD
IPC: F02M29/00
Filed: 2006-11-06
Abstract: An induction and fuel delivery system for one or more cylinders of a piston internal combustion engine comprising a centrifuge cyclone into which a flow of heated air is tangently discharged to generate a sustained rotational vortex, a fuel injector delivers an atomised or misted flow of fluid, gaseous or liquid fuel into the cyclone where the fuel undergoes flash evaporation and energetic mixing with the heated air. The air-fuel mixture is ducted from the base of the cyclone to the inlet tract or pipe of the cylinder to allow mixing with the induction air before entering the cylinder via the inlet valve for combustion to provide work energy. The fuel injector is prevented from overheating by a coolant jacket with coolant from the cooling system of the engine or thermal ceramic insulation. The cyclone has an interior bullet located on the central axis to prevent separation of less dense air-fuel components, and the conical base has a sawtooth cross-section to promote mixing. The heated air for the cyclone is reheated by waste heat from the engine to a temperature range of 20-300 degrees Celsius, substantially to 85-90°C. The process is monitored via sensors supplying data to a control unit that modulates various outputs to operate valves to control air and fuel flows.
Patent NZ-580783-A (NZ)
Title: Stable water in oil in water double emulsions comprising two emulsifiers of differing molecular weights
Inventor: FOLMER BRITTA
IPC: A23L29/10
Filed: 2008-06-27
Abstract: Disclosed is a double emulsion comprising an internal aqueous phase dispersed in an oil phase forming a water-in-oil emulsion, said water-in-oil emulsion being dispersed in an external aqueous phase, wherein the water-in-oil emulsion comprises at two different emulsifiers having different molecular weights, whereby one emulsifier is glycerol monooleate (GMO) and a second emulsifier is a polyglycerol polyricinoleic acid (PGPR) having a molecular weight of more than 1200 g/mol, wherein at least the internal aqueous phase comprises solutes, and wherein the external aqueous phase comprises whey protein isolate, amidated low methoxy pectin, egg yolk or a mixture thereof.
Patent NZ-583033-A (NZ)
Title: Tricyclic bridged cyclopentanedione derivatives as herbicides
Inventor: TYTE MELLONEY
IPC: C07D493/08
Filed: 2008-08-06
Abstract: Disclosed are tricyclic bridged cyclopentanedione derivatives represented by general formula (I). An example of a compound of formula (I) includes carbonic acid (1RS,2SR,6RS,7SR)-5-oxo-4-(2,6-diethyl-4-methylphenyl)-10-oxatricyclo[5.2.1.02.6]-dec-3-en-3yl ester ethyl ester. The compounds are used to control grasses and weeds in crops.
Patent NZ-583781-A (NZ)
Title: Pea Line 08510617
Inventor: WEBSTER DAVID
IPC: A01H5/10
Filed: 2010-03-08
Abstract: Disclosed is pea line 08510617 that exhibits a combination of traits comprising mid-season production of a freezer pea, with intermediate sieve size, afila foliage, resistance to Fusarium wilt Race 1, resistance to downy mildew and resistance to pea enation virus.