baber/WOPTO huggingface dataset:
Patent CA-3016092-A1 (CA)
Title: Forme polycristalline de base libre ou de sel d'acide d'inhibiteur d'egfr, procede pour sa preparation et application
Inventor: CHEN ZHONGKE
IPC: A61P35/00
Filed: 2016-12-23
Abstract: L'invention concerne une forme polycristalline de base libre ou de sel d'acide d'inhibiteur d'EGFR, un procédé pour sa préparation et une application. La présente invention concerne plus particulièrement une forme polycristalline de base libre ou de sel d'acide de N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(diméthylamino)éthyl)(méthyl)amino)-4-méthoxyphényl)acrylamide, un procédé pour sa préparation et une application de la forme polycristalline dans la préparation d'un médicament traitant une maladie médiée par une activité mutante d'EGFR. La présente invention est utilisée pour inhiber l'activité d'un mutant L858R d'EGFR, d'un mutant T790M d'EGFR et d'un mutant d'activation de délétion d'exon 19, etc., peut être largement appliquée dans la prévention et le traitement du cancer, en particulier du cancer du poumon non à petites cellules et d'autres maladies associées, et on s'attend à ce qu'elle se développe en une nouvelle génération d'inhibiteurs d'EGFR.
Patent CA-3017571-A1 (CA)
Inventor: ROSS DUNCAN
IPC: A61L15/44
Filed: 2016-03-16
Abstract: The present disclosure relates to methods of treatment for various diseases, including burn and chronic obstructive pulmonary disease, involving administration of compositions comprising membrane-enclosed vesicles. The membrane-enclosed vesicles may be derived from a stem cell such as a mesenchymal stem cell.
Patent CA-3020734-A1 (CA)
Title: Systemes et procedes de virtualisation dans un environnement informatique distribue comprenant un moniteur mobile
Inventor: WRIGHT CAMERON LLOYD
IPC: G06F9/44
Filed: 2017-04-12
Abstract: La présente invention concerne des systèmes et procédés décrits en détail pour un groupe de dispositifs mobiles comprenant une application sans états virtualisant une instance d'une application virtuelle à états. Dans des modes de réalisation décrits à titre d'exemple, un moniteur mobile au sein d'un contrôleur est configuré pour initialiser une session entre l'application sans états d'au moins un des dispositifs mobiles et la machine virtuelle à états du contrôleur en réponse à un premier message de demande provenant du ou des dispositifs mobiles en question. Le moniteur mobile est en outre configuré pour intercepter un deuxième message de demande du ou des dispositifs mobiles au contrôleur, destiné à la machine virtuelle à états, qui comprend des données cryptées, envoyer les données cryptées à un système distant pour décrypter les données cryptées, recevoir les données décryptées provenant du système distant, et envoyer le deuxième message de demande et les données décryptées à la machine virtuelle à états.
Patent CA-3021200-A1 (CA)
Title: Container gripper assembly
Inventor: HARKLEROAD WILLIAM
IPC: B25J15/04
Filed: 2017-04-19
Abstract: Various examples are directed to a container gripper assembly comprising a first jaw member and a second jaw member. The first jaw member may comprise a first plurality of pivotable inserts and the second jaw member may comprise a second plurality of pivotable inserts. The first jaw member may be movable towards the second jaw member to grip a container between the first plurality of pivotable inserts and the second plurality of pivotable inserts.
Patent CA-3023089-A1 (CA)
Inventor: ELLIOTT SARAH
IPC: A61K48/00
Filed: 2017-05-05
Abstract: Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an anti-IL-6 and/or anti-CD 126 synthetic antibody. The disclosure also provides a method of preventing and/or treating disease in a subject using said composition and method of generation.
Patent CA-3024264-A1 (CA)
Inventor: WONG WILLIAM SAI YAU
IPC: C09D133/04
Filed: 2017-05-10
Abstract: L'invention concerne un film comprenant un réseau d'interpénétration, ses utilisations et ses procédés de fabrication. Le film produit présente une durabilité, une résistance chimique et une transparence favorables. Le film est produit à partir d'un réseau d'interpénétration formé sous la forme d'une suspension colloïdale dans un solvant organique et un solide à particules.
Patent CA-3025576-A1 (CA)
Inventor: TENHOUTEN BROC WILLIAM
IPC: B21C23/14
Filed: 2017-06-09
Abstract: A metal extrusion and nodes based structure is provided. The structure comprises one or more arc members connected by one or more node members, wherein the arc comprises (i) a wing feature which is configured to mate with one or more non- structural components, (ii) an internal passage feature which is configured to be inserted into a connecting feature of the corresponding node member, and (iii) one or more keying features formed from a mating interface with the corresponding node member.
Patent CA-3026522-A1 (CA)
Inventor: SMITH KEVIN W
IPC: A61B17/068
Filed: 2008-10-04
Abstract: An electrically operated surgical instalment includes a surgical end effector having an actuation assembly effecting a surgical procedure when actuated and a handle connected to the end effector for actuating the assembly. A part of the assembly moves between start and fully actuated positions. The handle has a self-contained power supply and a drive assembly disposed entirely within the handle. The drive assembly has an electrically powered motor and a controller electrically connected to the power supply and to the motor. The controller selectively operates the motor. A transmission mechanically connects the motor to the moving part and selectively displaces the moving part anywhere between the start and fully extended positions when the motor is operated. A manual release is mechanically coupled to the transmission to selectively interrupt the transmission and, during interruption, displaces the moving part towards the start position independent of motor operation.
Patent CA-3031770-A1 (CA)
Inventor: BOGDAN MARY C
IPC: C08K5/05
Filed: 2017-07-25
Abstract: Blends, polyol premix compositions, methods of forming such compositions, foamable compositions using the premix compositions, methods of preparing foams containing the premix compositions, and foams made using the premix compositions are described. The polyol premix composition includes a polyester polyol; halogenated olefin blowing agent; and a distribution-enhancing component. In the polyol premix composition, the blowing agent, the polyester polyol, and the distribution-enhancing component form a substantially uniform composition.
Patent CA-3033339-A1 (CA)
Inventor: LI YIQUN
IPC: G06Q10/06
Filed: 2017-06-27
Abstract: Dans un mode de réalisation, la présente invention concerne un procédé comprenant la détermination, dans des données de rendement reçues, d'un ou plusieurs passages, chaque passage incluant une pluralité d'observations. Pour chaque passage parmi le ou les passages, une ou plusieurs dérivées distinctes sont déterminées, et sur la base de la ou des dérivées distinctes, des premières données aberrantes sont générées. Des premières données filtrées sont générées en retirant les premières données aberrantes des données de rendement. De plus, pour chaque observation dans les données de rendement, une pluralité d'observations voisines les plus proches est déterminée et utilisée pour déterminer une pluralité de différences absolues dans la valeur de rendement. Sur la base de la pluralité de différences absolues, des secondes données aberrantes sont déterminées. Des secondes données filtrées sont générées en retirant les secondes données aberrantes des premières données filtrées. En utilisant une couche présentation d'un système informatique, une représentation graphique des secondes données filtrées est générée et affichée sur le système informatique.
Patent CA-3035169-A1 (CA)
Title: Three column hydrocarbon recovery from carbon dioxide enhanced oil recovery streams
Inventor: PRIM ERIC
IPC: C07C7/00
Filed: 2016-08-29
Abstract: A method for recovering hydrocarbons with only three multistage columns includes receiving a carbon dioxide recycle stream. The carbon dioxide recycle stream is separated in a first multistage column to produce a purified carbon dioxide recycle stream and a light hydrocarbon stream. The light hydrocarbon stream is separated in a second multistage column to produce a second purified carbon dioxide recycle stream and a natural gas liquids stream. The natural gas liquids stream is separated in a third multistage column to produce a C3 hydrocarbon product stream and a C4-C8 hydrocarbon product stream. The first multistage column, the second multistage column, and the third multistage column are the only three multistage columns used in the method.
Patent CA-3035514-A1 (CA)
Title: Film de xerogel hydrophobe et son procede d'utilisation pour reduire la condensation
Inventor: MARION OLIVIER
IPC: C09K3/18
Filed: 2017-09-08
Abstract: La présente invention concerne généralement des films de xérogel hydrophobes réduisant la condensation. Plus particulièrement, l'invention concerne un film hydrophobe réduisant la condensation à base d'ormosil (silice organiquement modifiée).
Patent CA-3035553-A1 (CA)
Inventor: GATER BRAHIM
IPC: E04H15/34
Filed: 2019-03-05
Abstract: L'invention concerne un abri temporaire de chantier muni d'un système de diffusion d'air. L'abri est une construction modulaire et temporaire constituée de tubes ronds en acier, perforés de trous équidistants et couverts d'isolants. L'abri est équipé de blocs-coussinets pour amortir les vibrations, fixé rigidement au sol d'un dispositif d'ancrage antidérapant, ce dernier sert à soutenir les colonnes montantes, et est, protégé des chocs mécaniques par des bacs à sable. L'abri relève du domaine du bâtiment et des travaux publics, destiné aux chantiers de la construction qui fonctionnent sous des conditions extrêmes. L'abri apporte une solution durable pour créer de meilleures conditions de travail en périodes extrêmes, pour susciter un environnement adéquat à la préservation de la qualité des matériaux et pour permettre à l'industrie du bâtiment de continuer à fonctionner durant les saisons hivemales. L'invention apporte une solution pour une meilleure performance économique au secteur de la construction.
Patent CA-3035982-A1 (CA)
Inventor: LAURENSAN FREDERIC
IPC: B22F3/105
Filed: 2017-09-07
Abstract: Method for manufacturing at least one part (8) of electroconductive material by additive manufacturing on a bed of powder, characterised in that it comprises the steps of manufacturing the part on a support plate of a first additive manufacturing machine, layer by layer, said part being bounded by an external contour surface portion which is opposite and spaced apart from said support plate, and which is connected to said support plate by at least one bridge of support material of the part, providing a reference element (51) on the support plate in a predetermined position, mounting said support plate on a second machine (60) for cutting said at least one part, and using a wire (62-66) of said second machine for cutting by electrical discharge machining said at least one part by passing it between said at least one part and said support plate, along and at the level of said surface portion.
Patent CA-3037345-A1 (CA)
Inventor: BAKER JOHN MARSHALL
IPC: A61L29/16
Filed: 2017-09-18
Abstract: The present invention relates to novel aminobisphosphonate compounds useful as antiwear and/or friction modifier additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, and methods for making and using the same.
Patent CA-3038246-A1 (CA)
Inventor: MATHIS MARK
IPC: A61M25/09
Filed: 2017-09-26
Abstract: A guidewire suitable for use in a system for implanting a lung volume reduction device comprises: an outer sheath having a proximal end and a distal end, and comprising a proximal section, a transition section, and a distal section, wherein the proximal section extends from the proximal end of the outer sheath to the transition section, and the distal section extends from the transition section to the distal end of the outer sheath, and wherein the distal section defines a bore extending from the transition section to the distal end of the outer sheath; and an inner core having a proximal end and a distal end, wherein the inner core extends through the bore of the distal section of the outer sheath, wherein the inner core is fixed to the outer sheath at the transition section, and wherein the distal end of the inner core is fixed to the distal end of the outer sheath at the distal end of the sheath.
Patent CA-3039539-A1 (CA)
Inventor: DOUBINSKI SERGE
IPC: G06Q30/02
Filed: 2017-10-12
Abstract: This disclosure relates to system, method, and computer program for providing a wish-list user interface within a web browser, for tracking "fully-stacked prices" for items in the wish list, and for alerting users to a drop in a fully-stacked price of an item in the wish list. A browser extension provides a wish list user interface within a user' s web browser. Via the user interface, a user is able to add products from different merchant websites to the wish list. As each item is added to the wish list, an initial multifactor-based price (i.e., the fully- stacked price) is calculated for the item. While an item remains in the wish list, a backend server continues to track the multifactor-based price for the item. In response to detecting a drop in a multifactor-based price for an item in the wish list, the browser extension alerts the user to the price drop.
Patent CA-3040648-A1 (CA)
Title: Detonation activated wireline release tool
Inventor: MULHERN ERIC
IPC: E21B29/02
Filed: 2019-04-18
Abstract: A detonator activated wireline release tool is provided for use in geological well operations that enables the wireline cable to be easily released from tool string equipment upon activation of a detonator housed within the release tool. The release tool has a wireline subassembly portion that is connected to a tool string subassembly portion during assembly. It is sometimes necessary to disconnect the wireline subassembly from the tool string subassembly at a time when accessing the either is not physically possible. Such release is achieved by sending an electronic signal that detonates an explosive load which actuates a latch through an expansion chamber. The latch shifts and allows the finger flanges previously connecting the subassemblies to disengage, thus releasing the subassemblies.
Patent CA-3041714-A1 (CA)
Inventor: TAKEBE TAKANORI
IPC: A61L27/00
Filed: 2017-11-03
Abstract: Disclosed herein are methods of making and using lipotoxic organoid models. In certain aspects, the methods may comprise the steps of contacting a liver organoid with a free fatty acid (FFA) composition. In one aspect, the FFA composition may comprise oleic acid, linoleic acid, palmitic acid, or combinations thereof.
Patent CA-3041785-A1 (CA)
Inventor: LASIC SAMO
IPC: A61B5/055
Filed: 2017-11-09
Abstract: According to an aspect of the present inventive concept there is provided a method of performing diffusion weighted magnetic resonance measurements on a sample, the method comprising: performing diffusion weighted magnetic resonance measurements on the sample, wherein said measurements includes: a first measurement with a first diffusion encoding sequence having a first diffusion weighting tensor representation B1 with at least two non-zero eigenvalues, a second measurement with a second diffusion encoding sequence having a second diffusion weighting tensor representation B2 with at least two non-zero eigenvalues, wherein the first tensor representation B1 and the second tensor representation B2 have a same number of non-zero eigenvalues, the eigenvalues of the first tensor representation B1 matching the eigenvalues of the second tensor representation B2, and wherein the first and the second diffusion encoding sequences are configured to present a matching average spectral content, and to present a different degree of spectral anisotropy.
Patent CA-3042848-A1 (CA)
Title: A photonic resonant motor
Inventor: CAMPANELLA CARLO EDOARDO
IPC: G02B6/293
Filed: 2017-06-01
Abstract: A photonic motor is disclosed that comprises: at least one optical radiation input; a first optical waveguides arrangement, including at least one first optical resonator lying in a first plane to form a static part of the motor in a predetermined coordinate reference system; an excitation optical waveguides arrangement coupled to the first optical waveguides arrangement at a predetermined optical mode coupling distance to the at least one first optical resonator and configured to receive at least one optical radiation of predetermined wavelength from the at least one optical radiation input and to optically couple the optical radiation to the at least one first optical resonator; at least a second optical waveguides arrangement, including at least one second optical resonator lying in a second plane parallel to the first plane at a predetermined stacking distance perpendicular to the planes, the second optical waveguides arrangement being configured to move in the second plane with respect to the first optical waveguides arrangement according to at least a predefined direction of movement, so as to form a moving part of the motor in the predetermined coordinate reference system, wherein the stacking distance is adapted to establish an evanescent-wave coupling of optical modes between at least one first optical resonator of the first optical waveguides arrangement and at least one second optical resonator of the second optical waveguides arrangement, in a proximity condition of the first and second optical resonator in a plane transversal to the first and second plane where local motion of the second arrangement occurs, the first and second optical resonator being adapted to guide at least one resonant symmetric mode at a predetermined first wavelength or at least one resonant anti-symmetric mode at a predetermined second wavelength or at least a combination or superposition of at least one resonant symmetric mode at a predetermined first wavelength and at least one resonant anti-symmetric mode at a predetermined second wavelength, as a function of the stacking distance as well as of the distance between the first and second optical resonator on the transversal plane, and wherein, when a resonant symmetric mode is selectively established, an attractive condition of the second optical resonator towards the first optical resonator is established that generates, on the second plane, a motion of approach of the second optical resonator towards the first optical resonator according to the predefined local direction of movement, or, when a resonant anti-symmetric mode is selectively established, a repulsive condition of the second optical resonator from the first optical resonator is established, that generates on the second plane a motion of departure of the second optical resonator from the first optical resonator according to the predefined local direction of movement.
Patent CA-3044710-A1 (CA)
Title: Methods and systems for automated pharmaceutical container sorting
Inventor: HOFFMAN ROBERT E
IPC: B65B5/10
Filed: 2019-05-29
Abstract: A pharmaceutical order filling system includes an order processing device, an automated dispensing device in communication with the order processing device for dispensing a pharmaceutical into a container. The system includes pallets for transporting containers and a container sorting device in communication with the order processing device, the container sorting device for transferring the containers from the pallets to distribution areas. The container sorting device includes a pallet unloading area for retaining a pallet in a pallet unloading position, an exception conveyor, a standard order conveyor, and a container manipulation device including a gripper assembly for moving containers in order from pallets to the exception conveyor or the standard order conveyor.
Patent CA-3048308-A1 (CA)
Inventor: DONOHOE NICHOLAS P
IPC: F04B47/14
Filed: 2019-06-27
Abstract: A pump jack with counterbalance system is provided, including a supporting structure, a linear actuator with a housing and a shaft, a first pulley carried by the shaft, a second pulley fixed above the first pulley, an elongate flexible member, and a weight carried by the shaft. The housing is vertically oriented and mounted to the supporting structure above a ground surface. The shaft has a first end received within the housing and a connection end that extends out of the housing and carries the first pulley and the weight. The linear actuator drives the shaft between extended and retracted positions. The elongate member passes around the pulleys and has a first end fixed relative to the housing and a second end connected to a surface rod, such that reciprocating movement of the shaft causes the surface rod to move vertically and the weight to act as a mechanical counterbalance.
Patent CA-3048536-A1 (CA)
Inventor: SERHAN AARON
IPC: G06Q10/08
Filed: 2019-07-02
Abstract: A method of tracking remotely captured sensor readings in relation to mobile or stationary assets. Remote assets with local sensors are associated with sensor interface device capable of capturing local sensor readings along with geolocation and timestamps, and transmitting such information via a network interface to a server for storage in a sensor record database. A user in communication with the server can indicate a sample request, via which a subset of sensor records for a particular time window is extracted and the sensor readings and geolocations displayed to the user. The information could be presented in graphic map format. The sensor interface device has a self-contained power supply not requiring power input, allowing for long term remote field use. The server and sensor interface device for use in association with the method is also disclosed.
Patent CA-3052336-A1 (CA)
Inventor: WALLEY DANIEL R
IPC: E02F3/88
Filed: 2019-08-16
Abstract: A hydro excavation system has: a vacuum hose; and a snorkel tube mounted to the vacuum hose and defining an ambient air inlet and an air outlet, the snorkel tube oriented so that the air outlet supplies air into a suction end of the vacuum hose, the snorkel tube being extended in a longitudinal direction along the exterior of the vacuum hose from the suction end to position the ambient air inlet above the suction end when the vacuum hose is in use. A  method includes operating a hydro excavation system to vacuum water, solids, or water and solids into the vacuum hose as part of an excavation.
Patent CA-3054069-A1 (CA)
Title: Dispositif de placement de catheter mi-long
Inventor: ISAACSON SHAWN RAY
IPC: A61M25/00
Filed: 2018-03-16
Abstract: L'invention concerne un dispositif d'insertion de cathéter (10) permettant de positionner et d'insérer un cathéter (14), en particulier un cathéter mi-long, dans un patient. Le dispositif d'insertion (10) comprend une aiguille d'introduction (18) qui s'étend à partir de l'extrémité distale du cathéter pendant l'insertion. Un ensemble actionneur à commande manuelle (20) est mobile par rapport à un boîtier pour déployer le cathéter (14) sur l'extrémité distale de l'aiguille d'introduction (18). Un mouvement pas à pas de l'actionneur (20) fait avancer le cathéter (14) par étapes sur l'aiguille d'introduction (18). Un mécanisme de transfert ou d'indexation (60, 76) fait avancer le cathéter et empêche la rétraction du cathéter une fois déployé.
Patent CA-3054317-A1 (CA)
Inventor: STOKES JENNIFER
IPC: C02F5/14
Filed: 2018-02-26
Abstract: The invention relates to compositions, methods of manufacture, and methods for reducing metal corrosion during alkaline cleaning. In particular, the method employs a hydroxyphosphono carboxylic acid in alkaline cleaning of hard surfaces.