baber/WOPTO huggingface dataset:
Patent AU-2002306596-B2 (AU)
Title: Analogs of thalidomide as potential angiogenesis inhibitors
Inventor: WEISS MICHAEL
IPC: A61P43/00
Filed: 2002-02-26
Granted: 2008-01-17
Abstract: A number of thalidomide metabolites having superior anti-angiogenic properties have now been isolated and identified. In addition, thalidomide analogs that mimic the effects of the isolated and identified active thalidomide metabolites, and variations of such thalidomide analogs, have been developed. Such thalidomide analog compounds show enhanced potency in the inhibition of undesirable angiogenesis without the undesirable effects of administration of thalidomide.
Patent AU-2002354724-B2 (AU)
Title: PCR sample handling device
Inventor: BORDENKIRCHER GARY L
IPC: B01L9/00
Filed: 2002-07-02
Granted: 2005-05-05
Abstract: A device for handling PCR microcards, each having an array of sample chambers closed by a transparent material on one side thereof, in relation to a PCR instrument, the device including a carrier having an apertured region with an array of holes corresponding in number and relative location with the array of sample chambers in each of the microcards, and a provision for retaining a microcard on the carrier so that the transparent material faces the apertured region with the reagent sample chambers aligned, respectively, with the holes in the apertured region, and so that the side of the microcard opposite the transparent material is unobstructed at least throughout the array of sample chambers. The device cooperates with the PCR instrument to ensure accurate positioning of the carrier and the microcard retained thereon for real time PCR processing.
Patent AU-2003236193-B2 (AU)
Title: A blade for a wind turbine and a method of assembling laminated profiles for a blade
Inventor: SORENSEN FLEMMING
IPC: F03D1/06
Filed: 2003-04-08
Granted: 2006-10-26
Abstract: The invention relates to a blade for use on a wind turbine and a method of assembling laminated profiles ( 3, 5 ) for a blade for a wind turbine. The development towards increasingly larger blades requires, that the technology of manufacture is reviewed and novel methods applied, in particular with regard to aspects regarding strength and weight. It is an object of the invention to provide a blade that can be manufactured more accurately and with large uniformity with regard to strength, from blade to blade, and which is lighter than prior art blades. Novel aspects of the invention regards that the wing comprises a beam part ( 2 ) which comprises at least a first part ( 4 ) and at least a second part ( 6 ), said first part ( 4 ) comprising at least one body part ( 12 ) connected to at least one assembly face ( 10 ) and to at least one abutment flange ( 14 ) said second part ( 6 ) comprising at least one body part ( 18 ) connected to at least one assembly face ( 16 ) and to at least one abutment flange ( 20 ); wherein the parts ( 4, 6 ) are adjusted by use of means for height adjustment ( 8 ) and connected to each other at the assembly faces ( 10, 16 ); and wherein the laminated profiles ( 3, 5 ) are assembled around the beam part ( 2 ) and glued against respective abutment flanges ( 14, 20 ). Hereby it is obtained that the height of the beam part can be adjusted in accordance with the thickness of the laminated profiles, such that the glued joint reaches the desired thickness, thereby an amount of glue is saved, since extra dosage is avoided, whereby the blade becomes less expensive and lighter.
Patent AU-2003238687-B2 (AU)
Title: Cosmetic and/or pharmaceutical compositions comprising dimthylsulphone for the cure and prevention of irritation, inflammation and cutaneous erythema
Inventor: AMBROSI GIANFRANCO DE PAOLI
IPC: A61K31/194
Filed: 2003-05-30
Granted: 2009-07-02
Abstract: The present invention has as subject a new composition for cosmetic or pharmaceutical use intended for external use to be applied both to undamaged and damaged skin or onto the mucosa to reduce or inhibit irritation, inflammation and cutaneous erythemia induced by events of an exogenous nature (irritations induced by chemical agents, pharmaceuticals, cosmetic ingredients, physical agents-such as, for example, solar radiation, ultraviolet radiation, ionising radiation, X rays, gamma rays, laser light-bacterial agents, viral agents, etc) and to photoprotect the skin from solar radiation and specifically from damage induced by ultraviolet radiation of types A, B and C. More particularly, the present invention refers to the use of dimethyl sulphone in the preparation of a pharmaceutical or cosmetic composition for topical use, to prevent and/or cure the above mentioned cutaneous manifestations.
Patent AU-2003280410-B2 (AU)
Title: Cytokine receptor zcytor17 multimers
Inventor: DASOVICH MARIA M
IPC: A61K38/00
Filed: 2003-01-21
Granted: 2009-04-02
Abstract: There is provided an antibody or antibody fragment that specifically binds to a multimeric or heterodimeric cytokine receptor, wherein the multimeric or heterodimeric cytokine receptor comprises: 
a first polypeptide consisting of amino acid residues 20-732 of SEQ ID NO:111; and 
a second polypeptide consisting of amino acid residues 28-429, amino acid residues 28-739 or amino acid residues 28-979 of SEQ ID NO:7.
Patent AU-2004256166-B2 (AU)
Title: Device for hot dip coating a metal strip
Inventor: TRAKOWSKI WALTER
IPC: C23C2/24
Filed: 2004-06-16
Granted: 2009-03-19
Abstract: The invention relates to a device for hot dip coating a metal bar (1), especially a steel strip, in which the metal bar (1) is directed vertically through a container (3) accommodating the molten coating metal (2) and through a guide channel (4) mounted upstream thereof. The inventive device comprises at least two inductors (5) which are arranged on both sides of the metal bar (1) in the area of the guide channel (4) and generate an electromagnetic field for retaining the coating metal (2) inside the container (3). In order to relax the coating bath, the distance (d) between the walls (6) that delimit the guide channel (4) is not kept constant in a direction (N) extending perpendicular to the surface of the metal strip (1) in the zone (H) of the vertical extension of the guide channel (4), which is located between the bottom side (7) thereof and the bottom area (8) of the container (3).
Patent AU-2004257209-B2 (AU)
Title: Exo-specific amylase polypeptides, nucleic acids encoding those polypeptides and uses thereof
Inventor: LIU WEI
IPC: A23L7/104
Filed: 2004-07-07
Granted: 2011-02-10
Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.
Patent AU-2004270288-B2 (AU)
Title: Liquid dispensing system compensation method and means
Inventor: GERALD ASTLEY CHRISTOPHER
IPC: B67D7/30
Filed: 2004-09-03
Granted: 2012-01-12
Abstract: The present invention relates to liquid dispensing systems. A method for compensating for variation in pumping rate in a liquid dispensing svstem is described where the liquid dispensing system (10) includes a reservoir (20) having a predetermined capacity and a pump (40) for pumping a plurality of predetermined amounts of fluid from the reservoir to a predetermined destination. The method of compensating includes the steps of determining first an initial pumping rate for the pump (40), then determining a current pumping rate for the pump and then further compensating the pump. The step of compensating includes comparing the initial pumping rate to the current pumping rate and adjusting for the difference between these rates.
Patent AU-2005200172-B2 (AU)
Title: Benzimidazole derivatives
Inventor: SAITOU HIROSHI
IPC: A61P37/08
Filed: 2005-01-14
Granted: 2007-08-23
Abstract: Benzimidazole derivatives and analogs (I) are new. Benzimidazole derivatives and analogs of formula (I) and their salts are new. [Image] R 1, R 2H, halo, trihalomethyl, CN, OH, 1-4C alkyl or 1-4C alkoxy, or R 1+ R 2OCH 2O, OCH 2CH 2or CH 2CH 2CH 2(all optionally C-substituted by 1-4C alkyl); A : 1-7C alkylene optionally substituted by halo, OH, NO 2, CN, Alk, OAlk (2 of which may form acetal), SAlk, SO 2Alk, 1-6C acyl, 1-6C acylamino, trihalomethyl, trihalomethoxy, oxo or phenoxy (optionally substituted by halo) and optionally interrupted by O, S, SO 2or NR 3; R 3H or Alk; Alk : 1-6C alkyl; E : COOR 3, SO 3R 3, CONHR 3, SO 2NHR 3, tetrazol-5-yl, 5-oxo-1,2,4-thiadiazol-3-yl or 5-oxo-1,2,4-oxadiazol-3-yl; G : 1-6C alkylene optionally interrupted by O, S, SO 2or NR 3and optionally substituted by halo, OH, NO 2, CN, OAlk (2 of which may form acetal), trihalomethyl, trihalomethoxy, phenyl or oxo; J : 4-10 membered heteroaryl (excluding imidazole) optionally substituted by halo, OH, NO 2, CN, Alk, OAlk (2 of which may form acetal), SAlk, SOAlk, SO 2Alk, 1-6C acyl, 1-6C acylamino, optionally substituted anilido, trihalomethyl, trihalomethoxy, phenyl, oxo, COOR 3or phenoxy (optionally substituted by halo); M : a bond or S(O) m; m : 0-2, and X : CH or N. ACTIVITY : Antiinflammatory; antiallergic; respiratory; osteopathic. MECHANISM OF ACTION : Chymase inhibitor. In assays, 4-(1-((1,4-dimethylindol-3-yl)methyl)benzimidazol-2-ylthio)butanoic acid (Ia) exhibited an IC 50value for human chymase of 1-10 nM (no specific data is given). In oral bioavailability studies in rats, (Ia) at 30 mg/kg after 30 minutes and 4 hours had a blood concentrations of 16.1 and 6.3 mu g/ml, respectively.
Patent AU-2005233474-B2 (AU)
Title: Follistatin variant polypeptide
Inventor: MURAKAMI TATSUYA
IPC: A61K38/00
Filed: 2005-04-15
Granted: 2010-12-09
Abstract: The object of the present invention is to provide a follistatin variant capable of specifically inhibiting GDF-8 activity without without inhibiting activin activity. The present invention provides a follistatin variant polypeptide, which (a) comprises follistatin domain I; (b) does not comprise an amino acid sequence that is represented by formula (I): Cys-(X 1 ) a -Cys-(X 2 ) b -Cys-(X 3 ) c -Cys-(X 4 ) d -Cys-(X 5 ) e -Cys-(X 6 ) f -Cys-(X 7 ) g -Cys-(X 8 ) h -Cys-(X 9 ) i -Cys wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , X 8 , and X 9  each independently represents the same or a different naturally occurring amino acid residue other than cysteine, "a" represents an integer between 2 and 6, "b" represents an integer between 3 and 7, "c" represents an integer between 7 and 11, "d" represents an integer between 0 and 4, "e" represents an integer between 1 and 6, "f" and "g" represent integers between 8 and 12, "h" represents an integer between 4 and 8, and "i" represents an integer between 11 and 15) and has 50% or more homology with the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 29; and (c) selectively inhibits GDF-8 activity as compared with its inhibition of activin activity.
Patent AU-2005311981-B2 (AU)
Title: Transpedicular intervertebral disk access methods and devices
Inventor: THANH NGUYEN VAN
IPC: A61B17/16
Filed: 2005-11-30
Granted: 2011-08-04
Abstract: Methods and devices for treating diseases and conditions that change the spacial relationship between the vertebral bodies and the intervertebral disks, or that cause instability of the vertebral column, or both, and a method and devices that allow the surgeon to access the intervertebral space to restore a more normal three-dimensional configuration of the space, with or without additionally fusing two adjacent vertebrae.
Patent AU-2006202567-B2 (AU)
Title: Process for granulation of low-moisture, high-lipid content processed foods and re-use thereof
Inventor: SHAH MANOJ
IPC: A23P1/02
Filed: 2006-06-15
Granted: 2012-11-01
Abstract: ABSTRACr A process for musing low-moisture, high-lipid processed food which is ground in a single unit operation in a short-duration manner. Grinding may be effected without the need for moving mechanical parts. The food product obtained from the grinding treatment of low moisture, high-lipid processed food is suitable for re-use in food production lines. 127 = a.l 13* jj 111a13 *-.a.~FIG 3.-..
Patent AU-2006202716-B2 (AU)
Title: Portable restraint system for a vehicle
Inventor: BOYLE DONALD C
IPC: B60N2/90
Filed: 2006-06-23
Granted: 2011-12-22
Abstract: PORTABLE RESTRAINT SYSTEM FOR A VEHICLE A portable restraint system (10) mountable to a vehicle seat (11) may comprise a booster seat (18), a restraint harness (20) mounted to the booster seat (18) and a mounting 5 harness (40) coupled to the restraint harness (20). The restraint harness (20) may be configured to restrain a passenger (19) positioned on the booster seat (18). The mounting harness (40) may have a connector (68) attached thereto configured to releasable engage an anchorage (21) of the vehicle. 10,110 14 42 19 43 40 1 38 -39 -- 3 20 35 24 6 27 23 25 1 28 El29 30 31 1,1
Patent AU-2006204997-B2 (AU)
Title: Genes and uses for plant improvement
Inventor: MARK ABAD
IPC: C12N15/90
Filed: 2006-01-12
Granted: 2011-09-01
Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
Patent AU-2006236040-B2 (AU)
Title: Interactive Television Program Guide with Remote Access
Inventor: BEREZOWSKI DAVID M
IPC: H04N21/431
Filed: 2006-11-16
Granted: 2008-11-20
Abstract: An interactive television program guide with remote access is provided. The interactive television program guide is implemented on interactive television program guide equipment. A remote program guide access device is connected to the interactive television program guide equipment by a remote access link to provide a user with remote access to program guide functions.
Patent AU-2006236928-B2 (AU)
Title: Method of altering the binding specificity of proteins by oxidation-reduction reactions
Inventor: MCINTYRE JOHN A
IPC: C07K14/765
Filed: 2006-04-06
Granted: 2011-06-23
Abstract: The binding specificity of at least one protein suspended or dissolved in a liquid medium is reversibly altered by exposing the protein to an oxidizing agent or an electric current. A masked protein such as an autoantibody can be detected, isolated and recovered from a biological fluid by subjecting the biological fluid to an oxidizing agent or an electric current to change the binding specificity of masked proteins contained therein.
Patent AU-2006288016-B2 (AU)
Title: A graffiti prevention system
Inventor: GEORGE BICKNELL ANTHONY
IPC: G08B21/00
Filed: 2006-09-08
Granted: 2011-08-11
Abstract: A graffiti prevention system for preventing application of graffiti to a surface(s). The system includes a control component (11) coupled to one or more modular components (21 , 31). The control component (11 ) has a solenoid valve (12) which is coupled to a liquid supply. A motion sensor (19) upon sensing movement near surface(s) activates the solenoid valve (12) to cause liquid to flow from a pressure manifold (13) to spray pipes (14) so that liquid issues from spray nozzles (15, 16) onto the surface(s) to prevent graffiti from being applied to surface(s).
Patent AU-2006306361-B2 (AU)
Title: Insufflating system, method, and computer program product for controlling the supply of a distending media to an endoscopic device
Inventor: KURZYNA PETER M
IPC: A61M31/00
Filed: 2006-10-23
Granted: 2012-10-04
Abstract: The present invention is directed to a system, method, and computer program product for controlling the supply of a distending media (such as an insufflating gas) from a distending media source to an endoscopic device so as to prevent the excess venting and/or waste of distending media. More specifically the present invention provides for the detection of a pressure level within a lumen of an endoscopic device and adjusts a supply parameter of the distending media based at least in part on the detected pressure level, and in some cases on the relationship between the detected pressure level and a user-defined threshold.
Patent AU-2006319001-B2 (AU)
Title: Oligonucleotides, use thereof, detecting method and kit for diagnosing the presence of H5 and N1 genes of the Influenza A virus
Inventor: TELLES JEAN-NOEL
IPC: C12Q1/70
Filed: 2006-11-23
Granted: 2013-03-14
Abstract: The invention concerns a double pair of oligonucleotides for amplifying two target sequences localized respectively in the H5 and N1 genes of the genome of the
Patent AU-2007214547-B2 (AU)
Title: Selecting and stabilizing dsRNA constructs
Inventor: MUNYIKWA TICHAFA R I
IPC: C12N15/11
Filed: 2007-02-12
Granted: 2012-09-20
Abstract: The invention provides methods for selecting nucleotide sequences that yield dsRNA- mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.
Patent AU-2007215218-B2 (AU)
Title: Variants in complement regulatory genes predict age-related macular degeneration
Inventor: GOLD ALBERT M
IPC: C12P19/34
Filed: 2007-02-13
Granted: 2013-09-19
Abstract: Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided.
Patent AU-2007270069-B2 (AU)
Title: Method for stem cell culture and cells derived therefrom
Inventor: PHILLIPS BLAINE WESLEY
IPC: C12N5/02
Filed: 2007-07-06
Granted: 2013-05-16
Abstract: There is described a method of promoting the attachment, survival and/or proliferation of a stem cell in culture, the method comprising culturing a stem cell on a positively-charged support surface. There are also provided a cell composition prepared according to the method of the invention.
Patent AU-2007288544-B2 (AU)
Title: Combined pharmaceutical formulation with controlled-release comprising Dihydropyridine calcium channel blockers and HMG-CoA reductase inhibitors
Inventor: WUK KIM SUNG
IPC: A61K9/52
Filed: 2007-08-24
Granted: 2011-09-22
Abstract: The present invention relates to a chronotherapeutic combination pharmaceutical formulation, which is designed to control the release of each ingredient of the combined drug in a predetermined rate based on the principle of the so-called chronotherapy, where drugs are administered to exhibit pharmacological activities at predetermined time intervals. The formulation of the present invention comprises a dihydropyridine, calcium channel blocker that affects cytochrome P450 enzyme, and a statin, lipid-lowering agent, as active ingredients. Further, it is prepared in such a manner that the respective release rate of the above ingredients can be controlled, thereby preventing antagonistic effects and side effects resulting from the interaction of the above ingredients, while maintaining the synergistic effect, and providing easy medication.
Patent AU-2007297578-B2 (AU)
Title: System and method for determining a fill status of a canister of fluid in a reduced pressure treatment system
Inventor: BRIAN LOCKE CHRISTOPHER
IPC: A61M1/00
Filed: 2007-09-19
Granted: 2011-11-17
Abstract: A reduced pressure treatment system is provided that includes a canister that is fluidly connected to a tissue site and is configured to receive fluid drawn from the tissue site under the influence of a reduced pressure. A reduced pressure source provides the reduced pressure and is fluidly connected to the tissue site by a fluid communication path, which may include a source conduit, the canister, and a target conduit. A sensing device communicates with the source conduit and is configured to sense a pressure in the source conduit. A valve communicates with the source conduit and is configured to vent the reduced pressure. A processing unit communicates with the sensing device and the valve and is configured to open the valve for a selected amount of time, determine a decay of reduced pressure, and determine a fill status of the canister based on the decay of reduced pressure.
Patent AU-2007307964-B2 (AU)
Title: Meal replacement compositions and weight control method
Inventor: MYERS MICHAEL D
IPC: A23L33/00
Filed: 2007-10-03
Granted: 2013-06-13
Abstract: A food composition having a high protein level and comprising DHA, preferably for use as a meal replacement, is administered to subjects in order to control their weight.
Patent AU-2007314125-B2 (AU)
Title: Changing reel strip layouts for a game played on a gaming system
Inventor: GOOD GARY SIMON
IPC: A63F13/10
Filed: 2007-09-21
Granted: 2012-08-02
Abstract: A method (700), apparatus (101) and gaming system (100) for playing a game comprising a base game and a feature game, are disclosed. The base game is a spinning reel game comprising a plurality of spinning reels (501 to 505). The gaming system (100) comprises a processor (205) for controlling the play of the base game and the feature game. The gaming system (100) also comprises at least one display device (214) connected to the processor (205) for displaying one or more screens of the game. The gaming system (100) also comprises input means (202) connected to the processor (205) and the display device (214), for use by a player in controlling one or more aspects of the game, wherein the processor (205) controls the game such that upon a trigger event occurring within the base game, a layout of the spinning reels (501 to 505) within a screen of the base game is changed to provide a new game area (800) within the screen for presentation of a feature game. The feature game comprises a plurality of feature symbols progressively moving from a first predetermined point of the new game area (800) to a second predetermined point of the new game area (800) with respective results of playing the game feature.
Patent AU-2007327423-B2 (AU)
Title: Substituted pyrazoles, compositions containing these, method of production and use
Inventor: DODSON MARK
IPC: A61P35/00
Filed: 2007-11-09
Granted: 2012-09-06
Abstract: The present invention relates to new chemical compounds, particularly to substituted pyrazoles, compositions containing these, and their use as drugs.
Patent AU-2008212050-B2 (AU)
Title: Stapler powered auxiliary device
Inventor: KREHEL GREGG C
IPC: A61B17/068
Filed: 2008-09-08
Granted: 2014-04-10
Abstract: STAPLER POWERED AUXILIARY DEVICE There is disclosed an auxiliary device for injecting material between the jaws (16, 18) of a surgical stapler (12). The auxiliary device includes a nozzle assembly (30) 5 having a discharge port (34) and a compression assembly (70) having at least one compression roller for forcing material out of the discharge port. The disclosed compression rollers (78, 80) may be formed of an incompressible or compressible material. The auxiliary device also includes a drive mechanism for moving the compression assembly (70) within a nozzle body (32) of the nozzle assembly (30). There io is also disclosed a rupturable capsule (64) for retaining material to be dispensed. 14 N-- 20 '20 38 - ---- -----38 -- Z 7a FIG. 1 3 32 S'-46 o 44 68 7( 78 5652 42 4 466 32 76 80 50 58 4 FIG. 2 62 48