baber/WOPTO huggingface dataset:
Patent AU-2019250363-A1 (AU)
Title: Atrial natriuretic peptide engrafted antibodies
Inventor: MAYER-BARTSCHMID ANKE
IPC: A61P9/12
Filed: 2019-04-10
Abstract: The present invention relates to an antibody or a fragment thereof comprising at least one heterologous amino acid sequence incorporated within at least one CDR region of said antibody or fragment thereof, wherein said at least one heterologous amino acid sequence comprises an N-terminal linker sequence (Nils), an Atrial Natriuretic Peptide (ANP) and a C-terminal linker sequence (Ctls). Optionally, at least a portion of said at least one CDR region is replaced by said at least one heterologous amino acid sequence incorporated therein. The present invention further relates to such antibody or fragment thereof for use in a method for treatment, a composition comprising such antibody or fragment thereof, a nucleic acid or a mixture of nucleic acids encoding such antibody or fragment thereof, a host cell comprising such nucleic acid or such mixture of nucleic acids and to a process for producing such antibody or fragment thereof.
Patent AU-2019256517-A1 (AU)
Title: Animal pathogen-derived polypeptides and uses thereof for genetic engineering
Inventor: URNOV FYODOR
IPC: A61K39/00
Filed: 2019-04-18
Abstract: Provided herein are polypeptides, compositions, and methods for use thereof for genetic and epigenomic engineering, including, genome editing and gene regulation. These polypeptides and compositions include nucleic acid binding domains that bind to a target nucleic acid of interest. The nucleic acid binding domains include repeat units derived from repeat units identified in proteins from animal pathogens such as bacterium of the order Legionellales and the species Legionella and Francisella.
Patent AU-2019263638-A1 (AU)
Title: Catheter, inflatable balloon for a catheter
Inventor: DERVAL NICOLAS
IPC: A61B5/02
Filed: 2019-05-02
Abstract: Medical device (1) having: ▪ a catheter (10), characterized in that it comprises a first lumen (LU
Patent AU-2019270556-A1 (AU)
Title: Substitution of the messenger RNA cap with two RNA sequences introduced at the 5' end thereof
Inventor: LEMOINE JÉRÔME
IPC: C12N15/115
Filed: 2019-05-15
Abstract: The invention relates to a messenger ribonucleic acid (mRNA) molecule devoid of a capping molecule, of which the cost of in vitro transcription synthesis is greatly reduced, comprising, from 5'-end to 3'-end, at least one copy of a consensus sequence GUCAGRYC(N
Patent AU-2019283785-A1 (AU)
Title: Stable aqueous dispersions of zinc phosphates
Inventor: CHAND UGESH
IPC: C05B9/00
Filed: 2019-12-16
Abstract: An aqueous dispersion comprising water and potassium zinc phosphate dispersed within the water.
Patent AU-2019363213-A1 (AU)
Title: Microbial cell with improved in vivo conversion of thebaine/oripavine
Inventor: HANSEN ESBEN HALKJAER
IPC: C12N15/80
Filed: 2019-10-10
Abstract: A recombinant microbial host cell having improved in
Patent AU-2019365654-A1 (AU)
Title: Cleavable activators of CXCR3 and methods of use
Inventor: WELLS ALAN H
IPC: A61K38/19
Filed: 2019-10-18
Abstract: Recombinant C-X-C motif chemokine ligand (CXCL) peptides modified to introduce a cleavage site for a protease, such as a protease activated during an inflammatory response, are described. The CXCL peptides have the capacity to activate CXCR3 until being cleaved by the protease. Proteolytic cleavage of the CXCL peptide minimizes the pro-inflammatory response and inhibits the development of fibrosis.
Patent AU-2019369303-A1 (AU)
Title: Binding and non-binding articulation limits for robotic surgical systems
Inventor: ROCKROHR BRIAN
IPC: A61B17/00
Filed: 2019-10-29
Abstract: A robotic surgical system and method of selectively binding articulation limits to a surgical instrument includes detecting a proximal or a distal linear movement of the surgical instrument, calculating a distance between a tool center point of the surgical instrument after the proximal or the distal linear movement and a remote center of motion, assigning and binding an articulation limit to the surgical instrument based on the calculated distance when the detected linear movement is distal linear movement, and assigning a non-binding articulation limit to the surgical instrument based on the calculated distance when the detected linear movement is proximal linear movement.
Patent AU-2019376065-A1 (AU)
Title: Pyridazinone compounds and uses thereof
Inventor: HUNT KEVIN
IPC: A61K31/501
Filed: 2019-11-06
Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.
Patent AU-2019379822-A1 (AU)
Title: Method for producing ceramic dental prosthesis parts, CAD/CAM machining station, computer program and blank made of final-strength dental ceramic
Inventor: SCHNEIDER HANS-CHRISTIAN
IPC: A61C13/38
Filed: 2019-11-18
Abstract: The invention relates to a method for producing ceramic dental prosthesis parts by way of a CAD/CAM machining station, comprising the following steps: - providing a disk-shaped ceramic blank, wherein the blank has the final strength; - attaching the blank in a mounting device of the CAD/CAM machining station; - controlling the CAD/CAM machining station for establishing an initial contact between the blank and the grinding tool in such a way that, due to the rotation of the grinding tool about the longitudinal axis (13) thereof, the entire contact surface (21) between the grinding tool and the blank has relative movement; and - machining the blank by way of the rotating grinding tool, proceeding from the initial contact, to produce the ceramic dental prosthesis parts.
Patent AU-2019383049-A1 (AU)
Title: Method and system to analyse pipeline condition
Inventor: BOHORQUEZ AREVALO JESSICA MARIA
IPC: F17D5/02
Filed: 2019-11-22
Abstract: A method and system for analysing a condition of a pipeline in real time is disclosed. The method and system comprise generating a transient pressure wave in fluid carried along the pipeline and detecting a transient pressure wave interaction signal responsive to the transient pressure wave where the pressure wave interaction signal has a time duration corresponding to a region of interest of the pipeline. The method and system further includes processing the transient pressure wave interaction signal to analyse the region of interest of the pipeline.
Patent AU-2019405686-A1 (AU)
Title: Method and device for determining the position of a mining and/or construction machine
Inventor: GUSTAVSSON HANS
IPC: E21B7/02
Filed: 2019-12-19
Abstract: The present invention relates to a method for determining the position of a mining and/or construction machine (100), the method comprising: determining presence of a first marker (M1-M4) and a second marker (M1- M4) in the surroundings of the mining and/or construction machine (100) by identifying the geometrical forms of the markers (M1-M4), determining direction and distance from the mining and/or construction machine (100) to the first and the second marker, respectively, calculating a mutual distance between the first marker (M1-M4) and the second marker (M1-M4) using said determined distances and directions to the markers from the mining and/or construction machine (100), identifying the first marker (M1-M4) and the second marker (M1-M4) by comparing the calculated mutual distance () between the first and second marker with mutual distances between markers obtained from a representation of the positions of a plurality of markers, and determining a position of the mining and/or construction machine (100) using the determined directions and distances to the identified first and second markers (M1-M4).
Patent WO-2021155423-A1 (WO)
Title: A device for managing orders in restaurants
Inventor: PERDIGUES KEVIN
IPC: G06Q50/12
Filed: 2020-12-16
Abstract: A device for managing orders in restaurants, the device comprising an elongated monitor configured to display order dockets in a single horizontal queue and capable of automatically splitting ordered food items into different courses on each docket and allowing the user of the device to manage the content of any docket and its sequence anywhere in the queue.
Patent AU-2020216186-A1 (AU)
Title: Oligonucleotide compositions and methods thereof
Inventor: BROWN JEFFREY MATTHEW
IPC: A61K31/7105
Filed: 2020-01-30
Abstract: Among other things, the present disclosure provides oligonucleotides, compositions, and methods for preventing and/or treating various conditions, disorders or diseases. In some embodiments, provided oligonucleotides comprise nucleobase modifications, sugar modifications, internucleotidic linkage modifications and/or patterns thereof, and have improved properties, activities and/or selectivities. In some embodiments, the present disclosure provides oligonucleotides, compositions and methods for HTT-related conditions, disorders or diseases, such as Huntington's disease.
Patent AU-2020223358-A1 (AU)
Title: Treating heart failure
Inventor: MCCULLY JAMES D
IPC: A61K35/12
Filed: 2020-02-14
Abstract: The disclosure relates to compositions comprising isolated mitochondria or combined mitochondrial agents, and methods of treating disorders using such compositions. The described methods are based, at least in part, on the discovery that isolated mitochondria themselves, and isolated mitochondria linked to a therapeutic agent, diagnostic agent and/or imaging agent, can be delivered to a patient's tissue by injecting them into the patient's blood vessels.
Patent AU-2020241513-A1 (AU)
Title: Wetness indicator free from halogen-containing species
Inventor: SECRIST KIMBERLY E
IPC: A61F13/42
Filed: 2020-03-12
Abstract: A hot melt wetness indicator comprising an adhesive base composition utilizing a halogen-free species, namely nitrazine yellow, to trigger color change in hygiene articles, such as disposable diapers, to serve as moisture or wetness indicator upon insult. In some embodiments of the invention, the wetness indicator turns from yellow to purple.
Patent AU-2020250287-A1 (AU)
Title: Control of carbon dioxide levels and ph in small volume reactors
Inventor: GOH SHIREEN
IPC: B01L3/00
Filed: 2020-10-09
Abstract: Strategies to control the level of dissolved carbon dioxide (C0 2 ) concentrations and/or pH in 
small volume reactor chambers, and associated articles, systems, and methods, are generally 
provided. In certain embodiments, the reactor chambers can be configured to contain at least 
one biological cell. See Fig. 1.
WO 2014/066774 PCT/US2013/066832 
1/13 
112.  
100 
110 
102 1 
; f 
108 
106 
114 115 
FIG.1I
Patent AU-2020256426-A1 (AU)
Title: Systems and methods for the synthesis of nitric oxide
Inventor: ZAPOL WARREN
IPC: A61M16/10
Filed: 2020-10-16
Abstract: Systems and methods for producing nitric oxide (NO) to be used in medical 
applications are provided. In some embodiments, systems and methods are provided 
for a NO generator that is capable of generating a desired concentration of NO to be 
provided to a respiratory system for inhalation by a patient.
Patent AU-2020258360-A1 (AU)
Title: Method and system for the filtration and stabilization of ultra-high gravity alcoholic beverages
Inventor: HAVEL FREDERIK
IPC: C12G3/08
Filed: 2020-04-10
Abstract: Methods and systems are described that filter and stabilize ultra-high gravity alcoholic beverages produced by forward osmosis. A rough ultra-high gravity alcoholic beverage may be received from a dewatering system and then passed on to a chiller as part of a post dewatering process. The ultra-high gravity alcoholic beverage may be held at a predetermined temperature for a specific amount of time such that the temperature of the ultra-high gravity alcoholic beverage is prevented from falling below a freezing point of the ultra-high gravity alcoholic beverage. The chilled ultra-high gravity alcoholic beverage is then passed through a number of filters of a filtration system. The filters may be arranged in an order progressing from coarse to fine filters, where haze compounds and their precursors are removed from the ultra-high gravity alcoholic beverage producing a clear and stable product.
Patent AU-2020268759-A1 (AU)
Title: Modified adeno-associated virus (AAV) particles for gene therapy
Inventor: HEPPENSTALL PAUL
IPC: C12N15/86
Filed: 2020-05-07
Abstract: The present invention relates to improved adeno-associated virus (AAV) particles for gene delivery and gene therapy. Provided are adeno associated virus (AAV) particles that comprise a modified capsid. The present invention further relates to methods for producing the improved AAV particles of this invention by removing natural binding sites in adeno associated virus (AAV) capsids and introducing ligand binding sites into said capsid to provide AAVs that transduce only particular cells of interest. An additional aspect of the present invention relates to modified AAV particles for use in the treatment of a disease and methods for treating a disease, comprising administering the modified AAV particles to a subject in need thereof. Yet a further aspect of this invention relates to the AAV particles of this invention for the transfection of cells, for example as a gene delivery tool in basic research.
Patent AU-2020274148-A1 (AU)
Title: Non-contact Heat Not Burn Heating Device
Inventor: ZHU XIAOHUA
IPC: A24F47/00
Filed: 2020-05-15
Abstract: A non-contact electronic cigarette heater, comprising a ceramic heating element (10), a smoke formation product bearing component (20), and a cooling tube (60). The ceramic heating element (10) comprises a heating body (11) and a heating circuit (12), the heating body (11) is in a column shape and the heating body (11) is internally provided with a porous channel (101), and the heating circuit (12) is provided on the heating body (11) so as to heat air by means of the porous channel (101); the smoke formation product bearing component (20) comprises a ceramic tube (21) and a blocking sheet (22), the blocking sheet (22) is provided in a cavity defined by the ceramic tube (21) to divide the cavity into a first cavity and a second cavity, the first cavity is suitable for placing a smoke formation product, and the second cavity is suitable for placing at least part of the ceramic heating element (10); the cooling tube (60) is provided above the ceramic tube (21) and separated from the ceramic tube (21), the inner diameter of the cavity defined by the cooling tube (60) is the same as the inner diameter of the first cavity to enable a cigarette holder of the smoke formation product to pass through, and the cooling tube (60) is used for cooling smoke passing through the cigarette holder. The temperature of the smoke produced is reduced and taste is improved while the amount of smoke is increased.
Patent AU-2020281175-A1 (AU)
Title: System and Method for Detecting and Regulating Microstructure Online with Electromagnetic Assistance
Inventor: ZHANG HAI’OU
IPC: G01N27/90
Filed: 2020-12-07
Abstract: The disclosure belongs to the field of metal additive manufacturing, and specifically 
discloses a system and a method for detecting and regulating a microstructure online 
with an electromagnetic assistance. The system comprises a forming device, a 
detecting device, a regulating device and a substrate, wherein, the forming device, the 
detecting device and the regulating device are located above the substrate, the 
detecting device is connected with the regulating device, and the regulating device 
comprises an electromagnetic shock regulating unit and an electromagnetic stirring 
regulating unit; in operation, a workpiece may be formed layer by layer on the 
substrate through the forming device, the detecting device performs a real time 
detection for the microstructure in a formed area, and transmits a detection result to 
the regulating device, and according to the detection result, the electromagnetic shock 
regulating unit may be used to perform the electromagnetic shock on a newly formed 
fused micro area, or the electromagnetic stirring regulating unit may be used to 
perform the electromagnetic stirring on a molten pool to regulate the microstructure of 
the workpiece. The disclosure may control grain size and reduce defects such as pores 
and incomplete fusion during a forming process, and has advantages of closed loop 
regulation, stability, and strong pertinence.  
Fig.1
Page 1/2 
1 2 3 4 
Fig.1
Patent AU-2020286301-A1 (AU)
Title: Transport trolley
Inventor: WEBERT DIRK
IPC: B62B5/06
Filed: 2020-12-10
Abstract: A child seat for a stackable transport trolley, in particular a stackable transport trolley 
with a backrest which is composed of plastic, is to be arranged on the shopping 
5 trolley so as to be pivotable about a horizontal axis and to which at least one seat is 
coupled in a sliding or pivotable manner, wherein the backrest is formed integrally, 
and wherein at least one subsection of the backrest is designed in the manner of a 
hollow body.  
0 
17158761_1 (GHMatters) P108659.AU.1
WO 2017/076666 PCT/EP2016/075426 
1/14 
/(Z 
40 
4i 4 /I
Patent AU-2020288708-A1 (AU)
Title: System and method for object recognition using 3D mapping and modeling of light
Inventor: KURTOGLU YUNUS EMRE
IPC: G06V10/145
Filed: 2020-06-05
Abstract: The present invention refers to a method and a system for object recognition via a computer vision application, wherein at least one object (110) to be recognized is illuminated by at least one light source (121, 122) having light source specific radiance values, and radiance data of a scene (130) including the object are measured when the scene (130) is illuminated by the light source (121, 122). Further the scene is mapped by a scene mapping tool (150) rendering at least a partial 3D map of the scene (130). The data received from the scene mapping tool (150) are analysed and merged with the light source specific radiance values, and, based thereon, radiance of light incident at points in the scene (130), particularly at the at least one object (110), are calculated and combined with the measured radiance of light returned to the sensor (140) from points in the scene (130), particularly from the at least one object (110), thus forming a model of light spectral distribution and intensity at the at least one object (110) in the scene (130). An object specific luminescence and/or reflectance spectral pattern of the at least one object is extracted out of the model of light spectral distribution and intensity and matched with luminescence and/or reflectance spectral patterns stored in a data storage unit (160). Thus, a best matching luminescence and/or reflectance spectral pattern is identified.
Patent AU-2020309202-A1 (AU)
Title: Novel cancer antigens and methods
Inventor: KASSIOTIS GEORGE
IPC: A61K39/12
Filed: 2020-07-03
Abstract: There are disclosed inter alia polypeptides and nucleic acids encoding said polypeptides which are useful in the treatment, prevention and diagnosis of cancer, particularly melanoma, especially cutaneous melanoma and uveal melanoma.
Patent AU-2020325726-A1 (AU)
Title: Fastening system for an electrical stimulation generator
Inventor: VICENTE MIRALLES RAIMUNDO
IPC: A61M25/02
Filed: 2020-07-17
Abstract: A fastening system (1) for an electrical stimulation generator (2), with a generator and an electrode, comprising a casing (4) for containing the generator (2) that presents identical first and second openings (7.1, 7.2) disposed on opposite sides; means for the connection of the electrode (5) to the first or second opening (7.1, 7.2) in the casing (4), formed by a first pass-through connector (13) for the electrode with an airtight valve (14); an airtight closing element (10) disposed at the opening in the casing (4) opposite that presenting the electrode (5) connection means; a device (6) for securing the electrode (5) to the skin, and; means for fastening the casing (4) to the body of the patient (3).
Patent AU-2020327593-A1 (AU)
Title: Method for differentiating epithelial stem cells
Inventor: LLUEL PHILIPPE
IPC: G01N33/50
Filed: 2020-08-07
Abstract: The subject matter of the present invent ion is a method for differentiating epithelia l stem cells, comprising culturing one or more epithelial stem cells in contact with an extracellular matrix in t he presence of an expansion medium, a bovine pituitary extract, a receptor tyrosine kinase ligand, a supernatant of primary fibroblasts and optionally, a Rho kinase inhibitor.
Patent AU-2020351219-A1 (AU)
Title: Vasculogenic fibroblasts
Inventor: SEN CHANDAN K
IPC: A61K31/00
Filed: 2020-09-18
Abstract: Compositions and methods are provided for reprogramming demal fibroblasts to exhibit vasculogenic properties including the ability to stimulate vasculogenesis
Patent AU-2020386084-A1 (AU)
Title: Product and method for improving cement performance
Inventor: PILLAR JAMES
IPC: C04B7/02
Filed: 2020-11-20
Abstract: Products, including treatment compositions, and methods for improving cement performance are provided. More specifically, products and methods for improving cement hydration, and thus cement performance, using vegetation are provided. The vegetation may be processed into a vegetative extract that may be used to create a treatment composition. The treatment composition may be used to enhance hydration of cement. The products and methods disclosed herein may be used to create a stronger, lower cost, and longer-lasting cementitious product.
Patent AU-2020396965-A1 (AU)
Title: Systems and methods for modeling structures using point clouds derived from stereoscopic image pairs
Inventor: MUNDY JOSEPH L
IPC: G06T17/20
Filed: 2020-12-03
Abstract: A system for modeling a roof structure comprising an aerial imagery database and a processor in communication with the aerial imagery database. The aerial imagery database stores a plurality of stereoscopic image pairs and the processor selects at least one stereoscopic image pair among the plurality of stereoscopic image pairs and related metadata from the aerial imagery database based on a geospatial region of interest. The processor identifies a target image and a reference image from the at least one stereoscopic pair and calculates a disparity value for each pixel of the identified target image to generate a disparity map. The processor generates a three dimensional point cloud based on the disparity map, the identified target image and the identified reference image, The processor optionally generates a texture map indicative of a three-dimensional representation of the roof structure based on the generated three dimensional point cloud.
Patent AU-2020407573-A1 (AU)
Title: Combinations
Inventor: SAMATAR AHMED ABDI
IPC: A61K31/519
Filed: 2020-12-16
Abstract: Disclosed herein are combinations of compounds for treating a disease or condition, such as cancer. A combination of compounds for treating a disease or condition can include a SERD inhibitor and a WEE1 inhibitor, along with pharmaceutically acceptable salts of any of the foregoing.
Patent AU-2020432954-A1 (AU)
Title: Method and device for decomposing, recombining and playing audio data
Inventor: MORSY KARIEM
IPC: G10L25/18
Filed: 2020-03-17
Abstract: The present invention relates to a method for processing and playing audio data comprising the steps of receiving mixed input data and playing recombined output data. Furthermore, the invention relates to a device 10 for processing and playing audio data, preferably DJ equipment, comprising an audio input unit for receiving a mixed input signal, a recombination unit 32 and a playing unit 34 for playing recombined output data.