baber/WOPTO huggingface dataset:
Patent NZ-223221-A (NZ)
Title: Separation of leucocytes and erythrocytes by sedimentation
Inventor: KLIMCHAK R J
IPC: A61K35/14
Filed: 1988-01-18
Abstract: Hydroxyalkyl celluloses are useful as sedimenting agents in the non-destructive separation of red and white blood cells. Intact WBC recovery is higher than with conventional methods. The white blood cells may be used in interferon production.
Patent NZ-228981-A (NZ)
Title: Thermobondable, hydrophilic bicomponent fibre and preparation thereof
Inventor: HANSEN ANDERS STAF
IPC: D01F/
Filed: 1989-05-03
Abstract: A thermobondable bicomponent synthetic fibre with a length of at least about 3 mm, adapted to use in the blending of fluff pulp for the production of hygiene absorbent products, the fibre comprising an inner core component and an outer sheath component, in which the core component comprises a polyolefin or a polyester, the sheath component comprises a polyolefin, and the core component has a higher melting point than the sheath component, and a process for producing said fibre. The sheath-and-core type fibre is preferably made permanently substantially hydrophilic by incorporating a surface active agent into the sheath component. The long bicomponent fibres form a strong supporting three-dimensional matrix structure in the absorbent product upon thermobonding.
Patent NZ-233560-A (NZ)
Title: 2,3-bis(1h-indole-3-yl)-maleinimide derivatives; pharmaceutical compositions and preparation thereof
Inventor: BARTH HUBERT
IPC: C07D491/056
Filed: 1990-05-04
Abstract: The invention relates to novel bis(1H-indol-3-yl)maleimide derivatives, a process for their preparation, pharmaceuticals containing these compounds and their use for the treatment of cardiac and vascular diseases such as thromboses, arteriosclerosis, hypertension, inflammatory processes, allergies, cancer and certain types of degenerative damage of the central nervous system and also disorders of the immune system and viral diseases.
Patent NZ-238655-A (NZ)
Title: Piperidyl-substituted indole derivatives and pharmaceutical compositions
Inventor: PERREGAARD JENS
IPC: A61K31/4427
Filed: 1991-06-21
Abstract: A method for treating anxiety in mammals comprising administering in an effective amount to said mammal an 1-aryl-3-(4-piperidyl)-indole derivative having the general formula:    <IMAGE>   wherein R1 is H, F, Cl, Br, methyl, methoxy or cyano; and R3 is H or methyl; or a pharmaceutical acceptable acid addition salt thereof.
Patent NZ-242482-A (NZ)
Title: Joint for co-axial tubes: swaged narrowed end seating within belled increased end: scaffold units or platforms with such components
Inventor: BINYON CHRISTOPHER
IPC: E04G7/30
Filed: 1992-04-24
Abstract: A work platform and scaffolding unit are disclosed. The work platform is made up of a number of scaffolding units assembled in various configurations. Each scaffolding unit has two posts (1) and at least two cross bars (2). The posts have a belled lower end (6) and a swaged top (5) which fit together to provide the assembly. Rigidity is obtained by two spaced apart points of contact in the joints.
Patent NZ-243118-A (NZ)
Title: Absorbent article with elasticized waistbands and having a predisposed, resilient waistband flexural hinge zone as part of the waistband
Inventor: BUELL KENNETH BARCLAY
IPC: A61F/
Filed: 1992-06-12
Abstract: Absorbent articles having a unique elastic waist feature improving dynamic fit as well as containment characteristics. The elastic waist feature preferably comprises an interconnecting panel zone, a first flexural hinge zone joining the interconnecting panel zone with the containment assembly, an elasticized waistband, and a second flexural hinge zone joining the elasticized waistband with the interconnecting panel zone. The elasticized waistband comprises a shaping panel zone; a waistline panel zone; and a predisposed, resilient, waistband flexural hinge zone joining the shaping panel zone and the waistline panel zone. The waistband flexural hinge zone is predisposed to allow the panel zones to flexurally bend about a defined axis or zone is resilient to provide a restoring force/moment that returns the panel zones to their preceding in-use configuration, especially when the elasticized waistband has been pretensioned by a closure system. The closure system dynamically creates/maintains lateral tension through the elasticized waistband thereby allowing the elasticized waistband to more dynamically expand and contract with the motions of the wearer. The absorbent article additionally preferably comprises a pair of elasticized side panels disposed in the second waist region. The elasticized side panels preferably comprise a "zero strain" stretch laminate and an extension panel. The present invention also relates to alternative waist features comprising "an expansive tummy panel" elasticized waistband.
Patent NZ-249208-A (NZ)
Title: Malaria vaccine, merozoite surface protein 1 fragment, vector
Inventor: HOLDER ANTHONY ARTHUR
IPC: C07K14/445
Filed: 1993-02-22
Abstract: PCT No. PCT/GB93/00367 Sec. 371 Date Oct. 4, 1994 Sec. 102(e) Date Oct. 4, 1994 PCT Filed Feb. 22, 1993 PCT Pub. No. WO93/17107 PCT Pub. Date Sep. 2, 1993Disclosed are novel polypeptides comprising the sequences substantially as shown in FIGS. 1 and 2, in isolation from sequences naturally occuring adjacent thereto in the merozoide suface protein MSP1. Also disclosed are vectors comprising nucleotide sequences encoding said polypeptides, host cells comprising said vectors and a vaccine comprising one or both novel polypeptides.
Patent NZ-256613-A (NZ)
Title: Oxygen scavenging polymer composition in the form of a film containing a transition metal catalyst and an unsaturated hydrocarbon polymer; use in preserving foodstuffs
Inventor: SPEER DREW VE
IPC: B32B27/32
Filed: 1993-09-24
Abstract: Improved compositions for scavenging oxygen are disclosed. These materials, characterized by low degree crystallinity and a glass transition temperature of lower than -15 DEG  C., have high oxygen scavenging rates at low temperatures. The composition comprises an ethylenically unsaturated hydrocarbon and a transition metal salt catalyst and can be incorporated into various types of layers. It is preferable that the composition be incorporated into layers of multilayered articles used for packaging oxygen-sensitive products such as food products.
Patent NZ-256719-A (NZ)
Title: Quinolone and acridinone derivatives and pharmaceutical compositions
Inventor: OHNMACHT CYRUS JOHN
IPC: C07D405/04
Filed: 1993-10-14
Abstract: Compounds of Formula (I) wherein R<2>, R<3>, R<4>, R<10> and R<11> have any of the meanings given in the specification, and their pharmaceutically acceptable salts are useful in the treatment of urinary incontinence. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of Formula (I) and intermediates.
Patent NZ-258881-A (NZ)
Title: Process for disintegrating cell dispersions or suspensions using ultrasonication
Inventor: STANZL KLAUS
IPC: C12N1/06
Filed: 1993-12-03
Abstract: Claimed is a method for the lysis of cell dispersions or cell suspensions by ultra sound treatment in an ultrasound flow through chamber using a synotrode which: (i) protrudes to 1/2 to 2/3 of its length into the cell, (ii) is at an angle of 80.5 to 88.5 deg.; (iii) has a ratio of length of immersion (in mm) to the sonication vol. (in ml) of 1:1.1-1:20 and (iv) a ratio of the length of immersion (in mm) to the solid material in soln. (mass percentage) of 1:0.002-1:2.2. Pref. an amplitude of 20-70 is used, the synotrode angle is 85.3 deg. and the concn. of solids is between 0.5 to 65 wt. per cent.
Patent NZ-264050-A (NZ)
Title: Benzospiroalkenes and pharmaceutical compositions
Inventor: CORDI ALEX
IPC: C07D513/10
Filed: 1994-07-20
Abstract: Compounds of formula (I): <IMAGE>  in which:   - X represents -CH2-, -(CH2)2-, -CH=CH-, -O-CH2-, S-CH2-, -SO-CH2- or -SO2-CH2-,   - Y represents an oxygen or sulphur atom or a group -NR6-, - R1 represents a hydrogen atom or a linear or branched (C1-C6)alkyl group, - R2 represents a hydrogen or halogen atom, a linear or branched (C1-C6)alkyl group (substituted or unsubstituted), a hydroxyl group, a linear or branched (C1-C6)alkoxy group or a linear or branched (C1-C6)alkylthio group, - R3 represents a hydrogen or halogen atom, a linear or branched (C1-C6)alkyl group (substituted or unsubstituted), a hydroxyl group, a linear or branched (C1-C6)alkoxy group or a linear or branched (C1-C6)alkylthio group, - R4 represents a hydrogen atom (provided that, in this case, R1 represents a hydrogen atom), a halogen atom, a linear or branched (C1-C6)alkyl group (substituted or unsubstituted) or a hydroxyl group, or else - R1 and R2, R2 and R3, R3 and R4 or R4 and X form, together with the carbon atoms which carry them, a benzene ring, provided that, in the case where R1 and R2 form a benzene ring, X is other than -CH2- or -(CH2)2-, - R5 represents a hydrogen atom or an amino group (substituted or unsubstituted),   - R6 has the same meaning as R1, their isomers and their addition salts with a pharmaceutically acceptable acid. Medicaments.
Patent NZ-269061-A (NZ)
Title: A prourokinase mutant that induces less fibrinogenolysis and non-specific plasminogen activation than its native form
Inventor: LIU JIAN-NING
IPC: C12N15/57
Filed: 1994-06-28
Abstract: The invention relates to thrombolytically active pro-urokinase (pro-UK) mutants comprising the amino acid sequence of native pro-UK, but including a mutation which causes the pro-UK mutants to induce less fibrinogenolysis and non-specific plasminogen activation than native pro-UK, to have at least a 10-fold lower intrinsic activity than native pro-UK, and to have substantially the same fibrin promotion and thrombolytic activity after plasmin activation compared to native pro-UK when administered to a patient. The figure depicts the flexible loop (amino acids 297-313), in which a substitution occurs. <IMAGE>
Patent NZ-276959-A (NZ)
Title: A container having a port; an adapter with a tapering passageway and a protector for sealing an end of the adapter
Inventor: ASWAD ANDREW D
IPC: B65D41/28
Filed: 1994-11-16
Abstract: The adaptor (10) has an open end closed by a protector (40) and an opposite end housing an injection site (46), the opposite end engages with a tubular member (32) for coupling to a port of a container. An intermediate portion (54) has a tapering interior portion to direct a cannula, inserted in the open end, to the injection site. The protector (40) has a cap portion (20) and plug portion (26), which plugs the open end. A ring (14) can be manually pulled to remove the protector from the adaptor. <IMAGE>
Patent NZ-312180-A (NZ)
Title: Device to engage and remove the transport cap of a container of flowable particulate material and to cover at least the rim of the cap during removal thereof
Inventor: SEMENENKO IVAN
IPC: B65D88/54
Filed: 1996-07-05
Abstract: An apparatus for handling flowable material, particularly particulate material, which is held in a discharge container such as an IBC having an opening normally covered by a transport cap, comprises a device which is adapted to engage and remove the transport cap and a device to cover at least a rim of the cap during such removal. The problem of contamination is overcome using the apparatus which is in the form of an annular metal (in the embodiment) cowl which has two peripheral spaced apart upstanding walls, the inner wall rising from an internal base in the embodiment and from which also rises the engaging and removing device, which in the embodiment shown comprises a pneumatic piston and cylinder arrangement. The piston carries an extractor in the form of an annular disc or spider having a depending peripheral wall which carries an inflatable ring or tire. The external surface of the inner wall carries at its rim a lip seal which is mounted over an inflatable ring. The outer wall is higher than the inner wall, and carries an annular seal too, which extends over the lip seal.
Patent NZ-333946-A (NZ)
Title: MHC binding peptide oligomers
Inventor: STROMINGER JACK L
IPC: A61K47/48
Filed: 1997-08-05
Abstract: Oligomers comprising at least two MHC binding peptides joined by a flexible molecular linker and an oriented cloning method for producing the oligomers. The oligomers can be used in connection with methods for specifically activating or inhibiting the activation of CD4+ or CD8+ T cells. Such methods provide therapeutic approaches for the treatment of tumours, autoimmune disorders, allograft rejection and allergic reactions.
Patent NZ-334351-A (NZ)
Title: Process for preparing plasticized proteinaceous materials involving the step of identifying compatible proteins and plasticizers
Inventor: ABDEL-MALIK MAGDY MALAK
IPC: A23J3/26
Filed: 1997-10-06
Abstract: The method of identifying compatible proteins and plasticizers for the formation of a plasticized proteinaceous material comprises: a) selecting a protein component; b) determining the solubility parameter of the protein component defined by the formula: d12 = dD12 + dP12 + dH12 wherein d1 is the total solubility parameter value of the protein component; dD1 is the solubility parameter value contributed by dispersive forces of the protein component; dP1 is the solubility parameter value contributed by the polar forces of the protein component and dH1 is the solubility parameter value contributed by hydrogen bonding forces of the protein component; c) selecting a plasticizer component having a second solubility parameter defined by the formula: d22 = dD22 + dP22 + dH22 wherein d2 is the total solubility parameter value of the plasticizer component; dD2 is the solubility parameter value contributed by dispersive forces of the plasticizer component; dP2 is the solubility parameter value contributed by the polar forces of the plasticizer component and dH2 is the solubility parameter value contributed by hydrogen bonding forces of the plasticizer component and d) matching a protein component with a plasticizer component wherein at least one of the following pairs of solubility parameter values d1 - d2, dD1 - dD2, dP1 - dP2 and dH1 - dH2 are within 15% of each other. The matched protein and plasticizer components can be combined to form a blend and then the blend can be treated to form a plasticized proteinaceous material wherein the plasticizer component is uniformly dispersed within the protein component wherein the step of treating the blend comprises heating the blend in the melt state at a temperature of from 20 to 140oC under controlled high shear conditions such that the plasticizer is dispersed or trapped within a denaturated matrix of the protein component to provide the plasticized proteinaceous material. This plasticized proteinaceous material can be combined with other ingredient to form a gum or confectionery composition.
Patent NZ-336311-A (NZ)
Title: Providing authentication of mobile phone, dialed digits and number of digits fed to hashing function
Inventor: ROSE GREGORY G
IPC: H04L9/32
Filed: 1997-12-19
Abstract: A method for authenticating the identity of a mobile station in mobile communication system comprises: a) receiving a sequence of dialed digits entered into a mobile station by a mobile station user which identify a target communication unit; b) receiving a number representing the number of digits in the sequence of dialed digits; c) generating a first number derived from the sequence of dialed digits and the received number; d) generating an authentication message in accordance with the first number; and e) transmitting the sequence of dialed digits and the authentication message from the mobile station to a remote base station.
Patent NZ-337850-A (NZ)
Title: Detecting the presence of a carcinogenic process in a subject in the asymptomatic phase of the disease using the tumour marker carbonic anhydrase II
Inventor: PUSCAS IOAN
IPC: C12Q1/25
Filed: 1998-03-13
Abstract: A rapid method and diagnostic kit for cancer diagnosis, i.e. for detecting the presence of a carcinogenic process in a subject in the asymptomatic or early phase of the condition is described. The method and kit involve an activator compound of carbonic anhydrase II, i.e. a tumour marker, that is present in the serum of subjects who have cancer. The following are provided: 1. a method for cancer diagnosis comprising: a. preparing a first reaction mixture by combining a diluted blood serum sample of the subject to be tested and a solution of purified carbonic anhydrase II; b. determining the activity of the carbonic anhydrase Il in the first reaction mixture; c. determining the activity of carbonic anhydrase II in a second reaction mixture containing all constituents of the first reaction mixture except the blood serum; and d. assessing the degree of activation of carbonic anhydrase II in step (b) relative to step (c); 2. a tumour marker present in the serum of subjects having cancer, that activates carbonic anhydrase II at concentrations of 1 pM or below; 3. a kit for performing the method for cancer diagnosis as defined in (1) above comprising a composition containing carbonic anhydrase II. The method - permits the screening of carcinomas in the asymptomatic phase, and in early the stages when carcinomas are undetectable by conventional methods; - is performed using a small quantity of blood serum; - is highly sensitive and the assessments are reproducible; - is economically feasible because of the low prices of the required reagents.
Patent NZ-503084-A (NZ)
Title: Method and apparatus for automatically forming monolayers from particulate matter separated from fluid samples
Inventor: GUIRGUIS RAOUF A
IPC: A61B5/00
Filed: 1998-08-25
Abstract: An automated apparatus and method for batch processing a group of samples in respective containers is disclosed. A mono-layer of particulate matter is filtered from each sample and deposited on a corresponding slide for examination. A controller coordinates each mechanism and sub-assembly of the apparatus, which comprises: a container support arranging a group of containers; a conveyer advancing said container support; a group of heads engaging respective containers at said head stage; a pump; a group of filters corresponding to said group of heads, each of said filters communicating with said flow of its respective sample and including: a membrane in a first branch of the sample flow and adapted for collecting a mono-layer of particulate matter and a frit being interposed in a second branch circumventing said membrane; a slide support arranging a group of the slides in a second pattern, and a second conveyer advancing said slide support to a deposit stage.
Patent NZ-506319-A (NZ)
Title: Animal registration ear tag, with part of this number being enlarged so as to be readily visible
Inventor: MIYAWAKI YUTAKA
IPC: A01K11/00
Filed: 1999-12-09
Abstract: The animal tag has an animal registration number CN of multiple digits with some part of this being enlarged and printed on this (or another side not shown) to indicate a farm number that is readily visible.
Patent NZ-518189-A (NZ)
Title: Oxazinoquinolones useful for the treatment of viral infections
Inventor: TURNER STEVEN RONALD
IPC: C07D491/06
Filed: 2000-09-28
Abstract: A compound of formula (I) useful in treating or preventing herpes viruses wherein, R1 is C1-6 alkyl, optionally substituted with -OH, -OC1-4 alkyl or het or R1 is 3-hydroxy-1-propynyl; wherein C1-6 alkyl is optionally partially unsaturated; wherein het is a radical of a five- or six- membered heterocyclic ring having one or two heteroatoms selected from the group consisting of oxygen, sulfur and N; or a pharmaceutically acceptable salt, racemate, solvate, tautomer, optical isomer or prodrug derivative thereof.
Patent NZ-520245-A (NZ)
Title: Compressed microparticles in a pharmaceutical implant comprising one or more drugs dispersed in a biodegradable polymer
Inventor: BOUTIGNON FRANCOIS
IPC: A61J3/08
Filed: 2001-01-24
Abstract: Described is a pharmaceutical implant for controllably releasing a drug in a subject and methods for manufacturing and administering the implant. The implant is made of associated microparticles of a drug dispersed in a biodegradable polymer. The microparticles are sufficiently associated so that the implant maintains a predetermined shape but are not fused together so as to form a single monolithic structure. The drug can be controllably released in a subject by administration of the pharmaceutical implant without the need for a suspending fluid.
Patent NZ-521712-A (NZ)
Title: Device for detecting analytes related to saliva sample pH for measuring drug concentration in blood
Inventor: LIANG GREG
IPC: G01N33/53
Filed: 2001-04-06
Abstract: A device (7) with a means for concurrent measurement of pH (10) and an analyte (8) from a single sample is disclosed, wherein this device (7) for concurrent measurement of pH and detection of an analyte(s) in solution comprises: a holding structure; a pH measuring section (10) within the holding structure; an analyte measuring section (8) within the holding structure; and wherein the presence or quantity of the analyte is dependent on the pH of the solution.
Patent NZ-523720-A (NZ)
Title: Novel compounds and their use as glycine transport inhibitors
Inventor: MOLTZEN EJNER KNUD
IPC: C07D333/72
Filed: 2001-07-19
Abstract: A compound of formula I; a pharmaceutical composition comprising said compound; and the use of the compound for the manufacture of a medicament for the treatment of diseases responsive to modulation of the glycine transporter, such as the positive and negative symptoms of schizophrenia, psychoses, dementia, pain, improving cognition, Alzheimer's disease, multi-infarct dementia, AIDS dementia, Huntingdon's disease, Parkinson's disease, amyotrophic lateral sclerosis or stroke.
Patent NZ-527354-A (NZ)
Title: Floorboards and methods for production and installation thereof
Inventor: PERVAN DARKO
IPC: E04F15/04
Filed: 2002-01-14
Abstract: A floorboard and an openable locking system therefor comprise an undercut groove on one long side of the floorboard and a projecting tongue on the opposite long side of the floorboard. The undercut groove has a corresponding upwardly directed inner locking surface at a distance from its tip. The tongue and the undercut groove are formed to be brought together and pulled apart by a pivoting motion which has its centre (C) close to the intersection between the surface planes (HP) and the common joint plane (VP) of two adjoining floorboards. The undercut in the groove of such a locking system is produced by means of at least two disk-shaped cutting tools whose rotary shafts are inclined relative to each other to form first an inner part of the undercut portion of the groove and then a locking surface positioned closer to the opening of the groove. An installation method for a floor of such boards comprises the steps of laying a new board adjacent to a previously laid board, moving the tongue of the new board into the mouth of the undercut groove of the laid board, angling the new board upward during continued insertion of the tongue into the undercut groove and simultaneously angling down the new board to the final position. A manufacturing method for manufacturing the undercut groove uses machining by means of at least two different rotary cutting tools whose rotary shaft is set at different angles. A wedge-shaped tool for laying of the floorboards is wedge-shaped with an upwardly directed engaging surface at its thicker end.
Patent NZ-529507-A (NZ)
Title: Plasmid maintenance system for antigen delivery
Inventor: GALEN JAMES E
IPC: A61P31/04
Filed: 1999-12-02
Abstract: The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid Maintenance System. The invention optimizes the maintenance of expression plasmids at two independent levels by: (1) removing sole dependence on balanced lethal maintenance functions; and (2) incorporating at least one plasmid partition function to prevent random segregation of expression plasmids, thereby enhancing their inheritance and stability. The Plasmid Maintenance System may be employed within a plasmid which has been recombinantly engineered to express a variety of expression products.