baber/WOPTO huggingface dataset:
Patent JP-2886171-B2 (JP)
IPC: A61K9/50
Filed: 1988-03-30
Granted: 1999-04-26
Abstract: This application describes the preparation and in vivo testing of surface coatings and matrix materials, which when applied to or caused to comprise the carriers for drugs and diagnostic agents, and administered in a fashion that allows efficient vascular access, causes the carriers to recognize determinants present or normal or focally diseased endothelium, and induces the following in vivo effects: (1) rapid, partial or total endothelial envelopment of the drug (diagnostic) carrier; (2) sequestration of the carrier and protecting entrapped agent from blood vascular clearance at an early time (2 minutes) when the endothelial pocket which envelops the carrier still invaginates into the vascular compartment; (3) acceleration of the carrier's transport across or through the vascular endothelium and/or subendothelial structures into the tissue compartment (interstitium); and (4) improvement of the efficiency with which the drug (or diagnostic) carrier migrates across the endothelium, or epi-endothelial or subendothelial barriers, such that a lower total drug dose is required to obtain the desired effect relative to that required for standard agents.
Patent JP-3008195-B2 (JP)
IPC: C07C69/614
Filed: 1987-06-10
Granted: 2000-02-14
Abstract: Compounds having anti-inflammatory and other activities. The compounds are derived from diterpenes, indol alkaloids, polyacetates, diaminobenzyl alcohols, diacylglycerol and bryostatins.
Patent JP-3206003-B2 (JP)
IPC: A61P11/06
Filed: 1995-07-10
Granted: 2001-09-04
Abstract: Heterobicyclic derivatives of formula (I) wherein R<1> is aryl which may have suitable substituent(s), ar(lower)alkyl which may have suitable substituent(s), halo(lower)alkyl, protected carboxy(lower)alkyl, acyl(lower)alkyl, heterocyclic group or heterocyclic(lower)alkyl which may have suitable substituent(s), R<2> is aryl which may have suitable substituent(s) or heterocyclic group, and R<3> is hydrogen, lower alkoxy or arylthio, and a pharmaceutically acceptable salt thereof which are useful as PDE IV and TNF inhibitors for the treatment of hepatitis in human beings and animals. <CHEM>
Patent JP-2656384-B2 (JP)
IPC: G01S13/87
Filed: 1992-08-19
Granted: 1997-09-24
Abstract: A system for continuously and precisely measuring the positions of a generally symmetrical object, e.g., a tennis ball, in motion in a predefined three-dimensional region, e.g., a tennis court, which transmits multiple radar signals from first, second, and third, spaced antenna devices, respectively, into the three-dimensional region. Multiple return signals are sensed and are compared with the transmitted signals to determine the phases of the return signals, to thereby obtain ambiguous ranges of the object. Ambiguities are removed by using the Chinese Remainder Theorem to obtain less-ambiguous ranges. Time-of-arrival range information is used in conjuction with the less-ambiguous ranges to provide unambiguous ranges over the range of interest. The unambiguous ranges are used to compute three-dimensional coordinates of the object that are accurate to within approximately 0.1 inches. A mathematical model defining boundaries of the three-dimensional region is completed by placing signal reflector devices on various boundary points of the three-dimensional region, and transmitting the radar signals when the object is not in the three-dimensional region. Coordinates of a projected trajectory are computed and compared with the actual coordinatres of the object, and certain characteristics are computed therefrom. Calibration of the system is maintained by placing signal reflector devices at various fixed locations within the region of interest and the return signals are processed to obtain an initial survey of the region and then to periodically resurvey the region.
Patent JP-2632401-B2 (JP)
IPC: C07D213/30
Filed: 1988-09-05
Granted: 1997-07-23
Abstract: Substituted phenyltrifluormethylethers having the formula (I): R?1-(A?1-Z?1)n?-A?2-Z?2-A?3-OCF3?, in which R?1, A?1, Z?1, n, A?2, Z?2 and A?3 have the meaning described in the first claim, are useful as components of liquid crystal phases.
Patent JP-3349516-B2 (JP)
IPC: B60R21/20
Filed: 1997-07-03
Granted: 2002-11-25
Abstract: A silicone composition and the uses thereof, particularly as a coating on an airbag for protecting the occupant of a vehicle in the event of a collision, are disclosed. The aim is to provide a silicone composition suitable for coating onto the inner surface of the airbag while significantly reducing the weight of the resulting coating layer to form a protective coating having enhanced high-temperature, mechanical and substrate-adhesion properties. Said aim is achieved in that the composition is free of reinforcing mineral fillers and consists of a mixture of (1) at least one polyorganosiloxane with alkenyl groups bound to the silicon; (2) at least one polyorganosiloxane with hydrogen atoms bound to the silicon; (3) a cross-linking catalyst; (4) an adhesion promoter comprising (4.1) at least one alkoxylated organosilane, (4.2) at least one epoxy-functional organosilicon compound, and (4.3) at least one metal chelate and/or metal alkoxide wherein the metal is selected from the group which consists of Ti, Zr, Ge, Li, Mn, Fe, Al and Mg; (5) at least one polyorganosiloxane resin; and (6) optionally at least one cross-linking inhibitor.
Patent JP-3149952-B2 (JP)
IPC: C12P7/40
Filed: 1992-04-30
Granted: 2001-03-26
Abstract: Addition of a water-soluble polyelectrolyte (i.e. an anionic or cationic polymer) significantly increases the hydrolysis rate of esters in the presence of lipases. The invention provides a process for hydrolysis of water-insoluble ester in the presence of a lipase characterized by the presence of a water-soluble polyelectrolyte. The invention also provides a method of increasing the rate of hydrolysis of water-insoluble ester in the presence of a lipase by incorporation of a water-soluble polyelectrolyte.
Patent JP-3544378-B2 (JP)
IPC: A61K39/395
Filed: 1994-09-13
Granted: 2004-07-21
Abstract: A novel class of proteins, semaphorins, nucleic acids encoding semaphorins, semaphorin peptides, and methods of using semaphorins and semaphorin-encoding nucleic acids are disclosed. Semaphorin peptides and receptor agonists and antagonists provide potent modulators of nerve cell growth and regeneration. The invention provides pharmaceutical compositions, methods for screening chemical libraries for regulators of cell growth/differentiation; semaphorin gene-derived nucleic acids for use in genetic mapping, as probes for related genes, and as diagnostic reagents for genetic neurological disease; specific cellular and animal systems for the development of neurological disease therapy.
Patent JP-3343115-B2 (JP)
IPC: C12N1/19
Filed: 1990-06-26
Granted: 2002-11-11
Abstract: Enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented.  The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes.  The enzymes are well-suited for use in detergent compositions.
Patent JP-2904932-B2 (JP)
IPC: C22C33/02
Filed: 1995-09-11
Granted: 1999-06-14
Abstract: Metallurgical powder compositions are provided which contain a metal powder in admixture with a solid, particulate polyether lubricant. The incorporation of the polyether lubricant enhances the green strength properties of compacted parts made from the powder compositions, and generally reduces the ejection forces required to remove the compacted part from the die cavity.
Patent JP-3765579-B2 (JP)
IPC: A01N25/28
Filed: 1991-08-22
Granted: 2006-04-12
Abstract: The invention relates to a preparation for the administration of drugs in the form of minute liquid droplets which are provided, in particular, with a membrane-like covering of one or more layers of amphiphilic molecules or with an amphiphilic carrier substance, in particular for transporting the drug in and through natural barriers and constrictions such as membranes and the like. The preparation contains a boundary-active substance in an amount corresponding to up to 99 mol% of the content of this substance by which the solubilisation point of the droplets is reached. The preparation is suitable for the non-invasive administration of antidiabetics, in particular of insulin. The invention also relates to a process for the production of such preparations.
Patent JP-3628327-B2 (JP)
IPC: A61Q19/10
Filed: 1994-10-28
Granted: 2005-03-09
Abstract: The present invention encompasses a personal cleansing bar comprising from 10 parts to 70 parts by bar weight of a distilled, topped C12-C18 acyl (topped cocoyl) isethionate (STCI). The bar of this invention contains little or no (0-2.8 parts) highly soluble acyl groups (sodium C6, C8, C10, C18:1 and C18:2 acyl isethionate). The bar of this invention is mild, smells better than a bar made with ordinary sodium cocoyl isethionate (SCI), is more stable in terms of both odor and color, and is easier to make. A preferred STCI bar contains a higher level of moisture without processing negatives which higher level of moisture contributes to better lather. The sodium topped cocoyl isethionate (STCI) also allows for an increase in levels of liquids and hygroscopic materials, in the bar formulation without the usual processing negatives.
Patent JP-3190349-B2 (JP)
IPC: F01P7/16
Filed: 1995-10-13
Granted: 2001-07-23
Abstract: PCT No. PCT/SE95/01188 Sec. 371 Date Jun. 16, 1997 Sec. 102(e) Date Jun. 16, 1997 PCT Filed Oct. 13, 1995 PCT Pub. No. WO96/15365 PCT Pub. Date May 23, 1996The present invention relates to a heat-storage device for a liquid-cooled internal combustion engine and intended for heating the engine prior to starting the same, wherein the engine block (2) has a coolant pump (3) and coolant circulating passageways, wherein the heat-storage device includes a thermally-insulated storage container (7) for storing heated coolant, a reciprocatingly movable plunger means (9) mounted in the container (7) and functioning to divide the container into two chambers (8, 8') which are connected with the inlet and outlet of the engine-block coolant passageways, and a pump (10) by means of which coolant can be passed from the engine-block passageways to the storage container (7), wherein the two chambers (8, 8') can be placed in flowcommunication with one another through the medium of at least one valve means (19) provided in the movable plunger means.
Patent JP-3234947-B2 (JP)
IPC: G01N33/577
Filed: 1993-04-22
Granted: 2001-12-04
Abstract: PCT No. PCT/EP93/00981 Sec. 371 Date Jan. 17, 1995 Sec. 102(e) Date Jan. 17, 1995 PCT Filed Apr. 22, 1993 PCT Pub. No. WO93/22675 PCT Pub. Date Nov. 11, 1993A method is revealed for the quantitative determination of the proportion of the free form of a thyroid hormone ligand in a sample of a biological fluid in which the ligand is present partly in the free form and also partly in a form in which it is bound to physiological binding proteins. In the first step, a ligand derivative of the thyroid hormone with an immunoglobulin, a labelled specific binder, and a test tube whose walls are coated with an excess of a protein material are provided. In the second step, a sample of the biological fluid containing an unknown amount of the free thyroid hormone ligand, a solution containing a known amount of the ligand derivative, and a solution containing a known, less than stoichiometric amount of the labelled specific binder are added to the test tube to form a liquid reaction mixture. In the third step, the reaction mixture is incubated to allow the free thyroid hormone ligand and the ligand derivative in the liquid reaction mixture to compete for the binding sites of the labelled specific binder, and to allow, in a concomitant slower reaction, the binding of the immunoglobulin part of the ligand derivative to the excess of the protein material on the walls of the test tube. In the fourth step, the remaining liquid reaction mixture is removed from the test tube. In the final steps, the amount of labelled specific binder bound to the walls of the test tube is determined and the amount of the free thyroid hormone ligand calculated.
Patent JP-4050310-B2 (JP)
IPC: C07K14/11
Filed: 1995-01-25
Granted: 2008-02-20
Abstract: This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated response can provide protection against invention by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.
Patent JP-2525127-B2 (JP)
IPC: C07D213/30
Filed: 1993-02-01
Granted: 1996-08-14
Abstract: The borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by the utilization of catalytic amounts of the new and valuable oxazaborolidine catalysts of formula (I).
Patent JP-2865428-B2 (JP)
IPC: A61M25/16
Filed: 1996-04-26
Granted: 1999-03-08
Abstract: This is a catheter assembly and a section of that catheter assembly. That catheter assembly may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter having an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The catheter sections made according to this invention may be used alone or in conjunction with other catheter sections either made using the concepts shown herein or made in other ways. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections due to the presence of stiff polymeric tubing or metallic tubing or composited materials in the stiffer section.
Patent JP-3016596-B2 (JP)
IPC: B22D41/50
Filed: 1996-03-04
Granted: 2000-03-06
Abstract: PCT No. PCT/DE96/00405 Sec. 371 Date Sep. 22, 1997 Sec. 102(e) Date Sep. 22, 1997 PCT Filed Mar. 4, 1996 PCT Pub. No. WO96/29166 PCT Pub. Date Sep. 26, 1996The invention is directed to an immersion nozzle for casting metal, especially steel, in plants for the continuous casting of thin slabs. On order to provide an immersion casting pipe that is easy to manufacture, has a long life, and enables the liquid metal to flow out in a uniform manner, it is suggested, according to the invention, that the pour-in part (11) is a pipe having a straight-surface front mouth (12), and the pour-out part (21) is constructed from plane-surface wall elements (22, 23). For this purpose, the circular cross-sectional area (AR) of the pour-in part (11) is in a relationship to the rectangular free cross-sectional area (AE) of the pour-out part (21) such that AR/AE>/=1.7.
Patent JP-4063881-B2 (JP)
IPC: A01N25/04
Filed: 1997-03-04
Granted: 2008-03-19
Abstract: The use of polymers (I) as biocides is new, where (I) comprises: (a) 0.1-100 mol. % vinylamine (VA) or ethyleneimine units; (b) 0-99.9 mol.% units derived from at least one monomer selected from N-vinylcarboxamides of formula CH2=CH-N(R1)-CO-R2 (II), vinyl formate, vinyl acetate, vinyl propionate, vinyl alcohol, (1-6C) alkyl-vinyl ethers, monoethylenically unsaturated 3-8C carboxylic acids, or their esters, nitriles, amides and anhydrides, N-vinylurea, N-vinylimidazoles and N-vinylimidazolines; and (c) 0-5 mol.% units derived from monomers with at least two ethylenically unsaturated double bonds. The sum of (a)-(c) is 100 mol.%. R1, R2 = H or 1-6C alkyl.
Patent JP-3322888-B2 (JP)
IPC: B65H1/26
Filed: 1998-02-03
Granted: 2002-09-09
Abstract: In a non-stop stack changing device, remaining-stack bars are pulled from the stack area one by one and out-of-line in relation to each other. To this end, a pull/push drive is provided, which makes it possible to push the remaining-stack bars simultaneously into the grooves of a pallet carrying a sheet stack. Furthermore, the pull/push drive makes it possible to pull the remaining-stack bars in pairs from inside outwards out of the stack area. In addition, the remaining-stack bars can be pulled in a first and second sequence in accordance with this model. An individual motor drive is provided for this purpose, which operates interlockingly on each individual remaining-stack bar.
Patent ES-2296461-B2 (ES)
Title: Procedimiento de prediccion y control de la capacidad de un cable de par trenzado con drenaje, apantallado con lamina de doble capa y con cubierta protectora, mediante la variacion del paso del trenzado.
Inventor: MARTINEZ-PENALVER FREIRE CARLOS
IPC: H01B13/02
Filed: 2005-07-26
Granted: 2008-11-01
Abstract: Procedimiento de predicción y control de la capacidad de un cable de par trenzado con drenaje, apantallado con lámina de doble capa y con cubierta protectora, mediante la variación del paso del trenzado. El procedimiento permite la predicción y el control de la capacidad eléctrica de un cable de par trenzado determinada por las dimensiones y la naturaleza de los elementos que lo conforman, y controlada mediante el parámetro paso del trenzado. El resultado de su aplicación es la obtención de un cable final de capacidad predefinida o la determinación de las características de diseño del cable a fabricar para satisfacer un valor de esta capacidad. El procedimiento y el producto de su aplicación son de interés en industrias de fabricación de cable destinado a transmisión de señal o a alimentación de circuitos electrónicos.
Patent ES-2351498-B2 (ES)
Title: Método y sistema para la realización de ensayos "in situ" y caracterización de terrenos heterogéneos o macizos rocosos intensamente fracturados.
Inventor: ALVAREZ VIGIL ARTURO
IPC: E02D1/00
Filed: 2010-07-07
Granted: 2011-07-15
Abstract: Método y sistema para la realización de ensayos
" in situ " y caracterización de terrenos heterogéneos o
macizos rocosos intensamente fracturados. El método comprende las
siguientes etapas: a) excavar una zanja; b) disponer unos medios de
presión (1) en la zanja con un sistema
cilindro-pistón (3); c) acoplar en el extremo del
conjunto cilindro-pistón (3) una placa (9) para
ejercer presión sobre el terreno; d) medir y aumentar gradualmente
la presión mediante el conjunto cilindro-pistón (3),
observando la deformación hasta alcanzar la rotura, y medir la
deformación a intervalos de tiempo regulares. El sistema para
realizar un ensayo " in situ " de este tipo de terrenos
comprende un conjunto de cilindro y pistón (3) que ejerce presión en
el terreno. De aplicación, entre otros, en sectores de maquinaria y
equipo mecánico industrias extractivas y construcción.
Patent ES-2388627-B2 (ES)
Title: Sombrilla plana de grandes dimensiones.
Inventor: ESCRIG PALLARES JOSE FELIX
IPC: A45B23/00
Filed: 2010-07-30
Granted: 2013-04-19
Abstract: Sombrilla plana de grandes dimensiones.#La sombrilla incluye un mástil (1) formado por puntales (2), en número de tres o más, articulados comúnmente entre sí a través de una pieza intermedia (3), que permite el plegado y desplegado en abanico de los extremos de dichos puntales (2) del mástil (1), con la particularidad de que en el extremo superior de los puntales (2) van fijados los extremos de respectivos flejes curvos (6) que soportan y tensan la tela (5) de la sombrilla, según una disposición en arco invertido de esos flejes (6), que quedan separados de la tela, estableciendo así el tensado de ésta, determinando una superficie plana susceptible de vincularse a otra colateralmente para ampliar la superficie de cubrición.
Patent AU-2001267639-B2 (AU)
Title: Improved combinatorial libraries by recombination in yeast and analysis method
Inventor: ABECASSIS VALERIE
IPC: C12Q1/68
Filed: 2001-06-13
Granted: 2006-02-02
Abstract: The present invention relates to a method for producing combinatorial functional expression libraries using a combinatorial library of nucleic acids belonging to the same gene family, comprising a step of cloning by recombination in yeast. The invention also relates to a method for producing functional mosaic proteins and for analyzing a combinatorial functional expression library, by determining a sequential footprint for each of the mosaic proteins of the library.
Patent AU-2001272588-B2 (AU)
Title: Paper machine fabric
Inventor: TAIPALE SEPPO
IPC: D03D11/00
Filed: 2001-06-25
Granted: 2005-05-26
Abstract: A paper machine fabric comprising two separate layers which are made of a yarn system (1) made up of warp and weft yarns forming the paper side and a yarn system (2) made up of warp and weft yarns forming the machine side. The yarn system (1) forming the paper side is arranged to comprise two warp systems (3,4) and two weft systems (5,6). The warp system made up of top warps (3) of the layer forming the paper side is interconnected with the warp system of the structure forming the machine side by means of binder yarns (9) by arranging the binder yarns (9) at the paper-side binding point to press the top warps (3) inside the fabric in such a manner that the binder yarns (9) are at the binding point under the surface of the fabric. <IMAGE>
Patent AU-2002230567-B2 (AU)
Title: Compositions for treatment of ocular neovascularization and neural injury
Inventor: BURKE JAMES A
IPC: A61K45/00
Filed: 2001-11-01
Granted: 2007-01-18
Abstract: Methods and compositions for the treatment of ocular neovascularization (CNV) and macular degeneration. The invention includes combining laser treatment with administration of a neuroprotectant.
Patent AU-2002303722-B2 (AU)
Title: Endobutton continuous loop for bone-tendon-bone
Inventor: TORRIE PAUL A
IPC: A61F2/38
Filed: 2002-05-13
Granted: 2006-11-02
Abstract: A method of securing a tissue graft within a bone passage includes providing a graft fixation member comprising a closed-loop having a pair of opposing loop sections and capturing a first loop section of the closed-loop within the fixation member. An opposing second loop section of the closed loop is passed through an opening in the tissue graft, and the second loop section of the closed loop is secured to the fixation member.
Patent AU-2002304993-B2 (AU)
Title: Thermoelastic inkjet actuator with heat conductive pathways
Inventor: MCAVOY GREGORY JOHN
IPC: B41J2/045
Filed: 2002-06-14
Granted: 2005-11-03
Abstract: A heater assembly for a printhead is provided having a heating element including a heating layer and a non-heating layer, and a heat conduction means positioned in the middle of the non-heating layer so as to be spaced from the heating layer to conduct heat generated by the heating element away from the actuator assembly.
Patent AU-2003218218-B2 (AU)
Title: Geo-intelligent traffic reporter
Inventor: PAREKH SANJAY
IPC: H04W4/02
Filed: 2003-03-17
Granted: 2008-12-18
Abstract: A traffic reporter gathers real-time information on traffic conditions within a network and sends out traffic reports to traffic managers. The traffic reporter analyzes the network and also gathers network information from the traffic managers and analyzers dispersed throughout the network. These traffic reports provide real-time information on network conditions to allow the traffic managers to route network traffic in the most efficient, reliable, and fastest manner.