baber/WOPTO huggingface dataset:
Patent DE-69523938-T2 (DE)
Inventor: STANIER WILLIAM
IPC: A61K8/25
Filed: 1995-09-09
Granted: 2002-09-05
Abstract: Granular composition comprising 45 to 98 % w/w of a water insoluble particulate, whereby 10 to 75 % of the water insoluble particulate is made from a water insoluble particulate material, having a weight mean particle size of less than 20 microns and an oil absorption capacity of 60 to 180 g/100 g and 10 to 75 % of the water insoluble particulate is made from a water insoluble particulate material, having a weight mean particle size of below 20 microns and an oil absorption 200 to 350 g/100 g, the granular composition having a particle size, by sieve analysis, of 95 % below 600 microns and 95 % above 40 microns.
Patent DE-69528632-T2 (DE)
Inventor: FUSAMOTO AKIRA
IPC: B29C69/00
Filed: 1995-08-02
Granted: 2003-06-26
Abstract: The present invention provides light reflector component having a reflective surface of sufficiently high accuracy. As shown in Fig. 2, an injection mold 3 used to manufacture a light reflector component of the invention includes a male half 3a and a female half 3b. A resin film 1 having a shape of light reflective surface is placed on a protrusion element 4 formed on the male half 3a of the injection mold 3 which is set in a clamp mechanism of an injection molding apparatus (not shown). After the injection mold 3 is closed, a molten resin 6 is injected into a space defined by the male half 3a and the female half 3b. <IMAGE>
Patent DE-69528716-T2 (DE)
Inventor: LINA CESAR Z
IPC: A61M1/00
Filed: 1995-08-21
Granted: 2003-03-20
Abstract: The appts. includes a porous pad which is permeable to fluids for introduction onto a wound. A dressing covers the wound and provides an air-tight seal around the wound. A drainage tube connects the pad to a suction pump so that negative pressure can be applied to the wound to draw fluids from the wound. The tube is connected to the pump via a canister for collecting fluids sucked from the wound. At least one filter is interposed between the canister and the pump. The filter is located in the canister which is removably attached to a housing for the pump. The canister is removably received in a recess in the housing. A detector determines when the canister is full of fluid by sensing change of capacitance as the canister fills up. The pad is a polymer foam with interconnecting cells.
Patent DE-69529425-T2 (DE)
Inventor: MUTCH ALAN
IPC: A61M60/31
Filed: 1995-03-15
Granted: 2004-03-04
Abstract: The flow of a biological fluid to an organ is computer-controlled so that the natural variation of such flow is simulated. Specifically described are control of a blood pump flow output during CPB to mimic normal pulsatile blood flow from the heart and control of a ventilator output to mimic normal breathing of healthy lungs. A pattern of variation over time of instantaneous flow of a biological fluid to an organ of a mammalian species is established, a variable control parameter for regulation of flow of the biological fluid to the organ is generated in accordance with the pattern, and the flow of biological fluid to the organ is controlled in accordance with the variable control parameter.
Patent DE-69530228-T2 (DE)
Inventor: GRABENKORT W
IPC: A61M16/18
Filed: 1995-01-27
Granted: 2004-04-29
Abstract: A connector (20) is provided for mounting on an anesthetic vaporizer (22) to connect the inlet of the vaporizer (22) with a discharge port (42) of a container (24) of liquid anesthetic (26). The connector (20) includes a first coupling (47) attachable to the vaporizer (22) and defining a first passage (61) communicating at one end with the vaporizer inlet. A second coupling (49) is attachable to the container (24) and defines a second passage (68) communicating at one end with the container discharge port (42). A third passage (70) defined by one of the couplings (47, 49) and communicates with one of the first and second passages (61, 68). A combination valve and mounting structure is cooperatively defined by the couplings (47, 49) to accommodate pivoting of the second coupling (49) to a closed position occluding the first and second passages (61, 68), to a raised fill position establishing communication between the first and second passages (61, 68), and to a lowered drain position in which the first and second passages (61, 68) communicate through the third passage (70).
Patent DE-69530647-T2 (DE)
Inventor: MESTRIC SILVIJA
IPC: C12N15/11
Filed: 1995-08-03
Granted: 2004-03-11
Abstract: The present invention relates to DNA sequences encoding insulin precursors of formula B-Pg-A, wherein B and A represent B- and A-chains, respectively, and Pg represents modified C-peptide or any number of amino acids comprising at least one glycosylation consensus site. The invention also relates to a process for the preparation of insulin by culturing suitable cells, preferably fungal cells, transformed with a vector comprising DNA sequence encoding insulin precursor of given formula. The invention further relates to DNA sequences encoding pharmaceutical peptides and proteins in which N-glycosylation consensus site is introduced in a non-essential site in any spacer region for higher expression and secretion of proteins.
Patent DE-69533104-T2 (DE)
Inventor: CAMBIER S
IPC: H02P6/08
Filed: 1995-06-30
Granted: 2004-10-14
Abstract: A drive system for a brushless DC motor (10) uses pulse width modulation (20), and phase timing advancement to maintain a constant power output during high speed use. The arrangement is well suited for driving a brushless motor (10) in an electric vehicle and the like.
Patent DE-69533599-T2 (DE)
Inventor: JOHNSON SCOTT C
IPC: G06F13/38
Filed: 1995-01-25
Granted: 2005-10-13
Abstract: A clock control unit is provided that controls the gating of a clock signal received by an internal baud generator of a universal asynchronous receiver/transmitter (UART) circuit during an active mode. The clock control unit monitors the UART circuit to determine whether the UART is currently idle. If the clock control unit determines that the UART is idle, the clock signal is gated by a synchronous clock gate circuit. Accordingly, the clock signal is not provided to the baud generator, and a corresponding baud rate signal that normally clocks the receiver state machine of the UART is not generated. Power consumption of the UART is thereby significantly reduced. When a certain predetermined system activity is thereafter detected by the clock control unit that indicates a need for activation of the UART, the clock control unit asserts a clock enable signal that causes the synchronous clock gate circuit to pass the clock signal to an input of the baud generator. The baud generator responsively generates the baud rate signal that clocks the receiver state machine as well as other internal portions of the UART. In one embodiment, the clock control unit causes the clock signal to be degated if the receipt of serial data is detected at the serial input line of the UART, if the receiver state machine is currently active, if the receiver FIFO and buffer register is not empty, if the transmitter FIFO and holding register is not empty, or if the transmitter state machine is active. <IMAGE>
Patent DE-69603453-T2 (DE)
Inventor: ORTEN BIRGER
IPC: A61B7/04
Filed: 1996-02-08
Granted: 2000-02-03
Abstract: An electronic stethoscope including a microphone, amplifying equipment, and a loudspeaker for the user, also comprises an adjustable filter circuit. The filter circuit has a bandpass effect, and the center frequency and bandwidth of the passband can be adjusted at will throughout the audible range by the user.
Patent DE-69603999-T2 (DE)
Inventor: COLIN BRUNO
IPC: F16K13/10
Filed: 1996-02-13
Granted: 1999-12-23
Abstract: A static valve (1) consists of a piece of tubing (2a) containing a fluid (2b). A cooling source (3) is situated in contact with the tube, large enough to freeze the fluid contained in the tube and seal it well enough to withstand pressure of up to 150 bar. The tube can also be quickly heated by an electrical current (5a) and (5b), fast enough to thaw frozen fluid in less than 10 seconds and clear the passage. The tube itself is made of a mechanically resistant metallic material, which will dissipate heat by an ohmic effect, generating heat in a controlled manner when an electric current is passed through it.
Patent DE-69608570-T2 (DE)
Inventor: YOUNG ALAN
IPC: D04H1/54
Filed: 1996-11-08
Granted: 2001-01-18
Abstract: A nonwoven that is exceptionally soft yet sufficiently strong for use in absorbent articles is disclosed. The soft, strong nonwoven includes fibers comprising polyethylene, at least a portion of which are consolidated. The soft, strong nonwoven has a cross-machine direction tensile strength of at least about 300 g/in and a cross-machine direction elongation at break of at least about 40%. The soft, strong nonwoven is preferably formed by permanently stretching an inelastic base nonwoven in the cross-machine direction. The preferred base nonwoven has certain properties which allow it to have sufficient strength after stretching, while being exceptionally soft, such that the resultant permanently stretched, soft, strong nonwoven is particularly suitable for use as a topsheet or a back sheet component in disposable absorbent articles. More specifically, the preferred base nonwoven has a cross-machine direction elongation at break of at least about 175% and a cross-machine direction tensile strength of at least about 400 g/in. A particularly preferred base nonwoven also has a filament denier of from 1.5 to 10, a basis weight of from 15 to 30 gsy, and, for thermal point bonded nonwovens, a consolidation area of from 4 to 40%.
Patent DE-69620002-T2 (DE)
Inventor: LEE WILLIAM
IPC: B29C44/00
Filed: 1996-11-08
Granted: 2002-11-14
Abstract: A dispenser for dispensing foamable compositions includes a first module comprising a first housing, a fluid flow fitting in the first housing, a shutoff valve in the first housing and in fluid communication with the fluid flow fitting. The dispenser further includes a second module comprising: a second housing, a valving chamber in the second housing for receiving fluid from the shutoff valve and the fluid flow fitting; and an attachment for securing the first and second modules to one another with the valving chamber in fluid communication with the shutoff valve and the fluid flow fitting so that foam precursors can travel from the foam fittings to the valving chamber, and be dispensed from the chamber to form foam.
Patent DE-69636724-T2 (DE)
Inventor: PINNAMARAJU PRASAD
IPC: A61K31/275
Filed: 1996-02-08
Granted: 2007-09-20
Abstract: Verapamil depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) an alginate component, such as sodium alginate, (2) an enteric polymer component, such as methacrylic acid copolymer, and (3) a pH independent gelling polymer, such as hydroxypropyl methylcellulose or polyethyleneoxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
Patent DE-69700911-T2 (DE)
Inventor: KAHN ANDREW
IPC: B01J23/02
Filed: 1997-03-14
Granted: 2000-05-04
Abstract: Propylene is oxidized to propylene oxide in the vapor phase using an oxygen-containing gas and a supported silver catalyst comprising silver and a support comprised in whole or in substantial part of certain alkaline earth metal compounds. The alkaline earth metal compound may, for example, be a calcium compound such as calcium titanate, tribasic calcium phosphate, calcium molybdate, or calcium fluoride, a magnesium compound such as magnesium aluminate, or a strontium compound such as strontium titanate. Such supports provide significantly higher selectivity to the desired epoxide than would be expected from the performance of related materials. Propylene oxide selectivity may be further enhanced through the introduction of nitrogen oxide species such as NO, alkyl halides such as ethyl chloride, and carbon dioxide into the oxygen-containing gas.
Patent DE-69705612-T2 (DE)
Inventor: BERNASCONI SERGIO
IPC: A44B19/26
Filed: 1997-01-06
Granted: 2001-10-25
Abstract: In a joint (4) for connecting slide (1) of a zipper and corresponding drawer (2) that includes a first cavity (3a) to connect it to bridge (6) of said slider (1) and a second cavity (5) for connecting it to a collar (2a) of said drawer (2), said first cavity is made in a separate part (3) that is not integral with joint (4) but is connected thereto by means of attachments.
Patent DE-69715888-T2 (DE)
Inventor: BIEDERMANN ELFI
IPC: C07D401/14
Filed: 1997-06-20
Granted: 2003-07-31
Abstract: The invention relates to a new pyridyl alkene and pyridyl alkine acid amides according to the general formula (I) as well as methods for their production, medicaments containing these compounds as well as their medical use, especially in the treatment of tumors or for immunosuppression.
Patent DE-69731195-T2 (DE)
Inventor: HIRAYAMA SATOSHI
IPC: C11D3/386
Filed: 1997-04-22
Granted: 2006-03-09
Abstract: Lipolytic enzymes with high activity at alkaline pH in the absence of Ca++ can be obtained from filamentous fungi of the genera Gliocladium, Verticillium and Trichophaea and that the lipolytic enzymes are effective for improving the effect of detergents. The lipolytic enzymes have a good washing performance, as expressed by the hydrolysis of oil on textile swatches. The amino acid sequences of the lipolytic enzymes are highly homologous.
Patent DE-69731939-T2 (DE)
Inventor: GOUDSMIT JAAP
IPC: C12Q1/6855
Filed: 1997-02-14
Granted: 2005-12-22
Abstract: The invention relates to methods for easily separating single stranded nucleic acid material from double stranded nucleic acid material in a sample containing both. By the right choice of at lease one chaotropic agent, preferably a guanidine salt, at a selected concentration and other suitable conditions such a chelating agents, pH and the like, it is possible to bind double stranded material to a solid phase such as silica particles, whereas single stranded material will not bind under those circumstances. By separating the silica particles from the sample the double stranded nucleic acid material is removed. It can easily be eluted from the silica particles. In a second step the single stranded material may be bound to a solid phase by selecting a different set of conditions. The particles can again be separated from the sample and the single stranded material may now be eluted. For very efficent separations, the process may be repeated. Following the separation of the two kinds of nucleic acid, either kind may be amplified. Methods of amplification are provided which do not need sequence data of the material to be amplified. In these methods a primer will be provided with an amplification motif and a random hybridization motif.
Patent DE-69733478-T2 (DE)
Inventor: WANG YUGUANG
IPC: C07D405/12
Filed: 1997-08-13
Granted: 2005-11-03
Abstract: 1,4 Di-substituted piperidine muscarinic antagonists of formula (I) or an isomer, pharmaceutically acceptable salt, ester or solvate thereof, wherein X is a bond, -O-, -S-, -SO-, -SO2-, -CO-, -C(OR<7>)2-, -CH2-O-, -O-CH2-, -CH=CH-, -CH2-, -CH(C1-C6 alkyl)-, -C(C1-C6 alkyl)2-, -CONR<17>-, -NR<17>CO-, -O-C(O)NR<17>-, -NR<17>C(O)-O-, -SO2NR<17>- or -NR<17>SO2-; R is cycloalkyl, optionally substituted phenyl or optionally substituted pyridyl; R<2> is H, alkyl, optionally substituted cycloalkyl, cycloalkenyl, t-butoxycarbonyl or optionally substituted piperidinyl; and the remaining variables are as defined in the specification, are disclosed. Compounds of formula (I) are useful for treating cognitive disorders such as Alzheimer's disease. Also disclosed are pharmaceutical compositions, methods of preparation and combinations of compounds of formula (I) with ACh'ase inhibitors.
Patent DE-69736306-T2 (DE)
Inventor: HART DEREK NIGEL JOHN
IPC: C12N15/09
Filed: 1997-05-29
Granted: 2007-06-14
Abstract: The invention provides isolated human DEC-205, its extracellular domain and functionally equivalent fragments thereof. Also provided are polynucleotides encoding same and vectors which include such polynucleotides. Further provided are methods of recombinantly producing human DEC-205, an extracellular domain thereof or a functionally equivalent fragment, and ligands that bind to human DEC-205 or a fragment thereof. Also provided are constructs for use in prophylaxis or therapy comprising such a ligand, human DEC-205 or an extracellular domain thereof coupled to a toxin or to an antigen capable of inducing a protective immune response in a patient.
Patent DE-69808012-T2 (DE)
Inventor: HIRAO YUTAKA
IPC: A61P37/04
Filed: 1998-10-23
Granted: 2003-08-14
Abstract: A method for producing an immunoglobulin preparation for intravenous injection, which comprises the steps of: fractionating an immunoglobulin-containing solution with 4 to 10 w/v% of polyethylene glycol having a molecular weight of from 1,000 to 10,000, at a pH value of from 4.5 to 6.5, an ionic strength of from 0.0001 to 0.1 M and a temperature of from 0 to 4 DEG C to recover a supernatant fraction; and concentrating the supernatant fraction at a pH of from 3.5 to 5.0.
Patent DE-69808038-T2 (DE)
Inventor: PREVOT GERARD
IPC: E05D5/12
Filed: 1998-12-23
Granted: 2003-05-22
Abstract: The fixed plate (2) of the hinge has a rear face cavity, apertures (4) and bearings (3) for the hinge pin (1). A security element (10) with an elastic base (11) fit into the cavity, the base having a positioning branch (12) which passes across the bore and a locking element which holds the hinge pin in place.
Patent DE-69816761-T2 (DE)
Inventor: MCKENNA CATHAL
IPC: B60K17/356
Filed: 1998-11-26
Granted: 2004-06-03
Abstract: There is provided a drive controller (50) for a hydraulic drive system (1), a three wheeled vehicle having a pair of transversely arranged in line of drive shaft assemblies and a single wheel drive shaft assembly each assembly comprising a drive unit 10 (20 & 30) having two separate drives (11 & 12; 21 & 22; and 31 & 32) and has for series operation secondary hydraulic feed lines (44 & 45) between one of the drives of the single (11, 12) drive units and one of the drives of each transverse drive unit (21, 22 and 31, 32). A pressure release valve (54) is provided in each secondary line (44, 45) which valve (54) is fed through a non-return valve (55). <IMAGE>
Patent DE-69818357-T2 (DE)
Inventor: LETZELTER ALAIN
IPC: B61D17/06
Filed: 1998-07-01
Granted: 2004-06-24
Abstract: The steel end frame (2), bolting on to the vehicle (1), accepts a completely equipped, prefabricated driver's cab (3), quick-release connections for all mechanical and electrical controls and circuits being provided at the vehicle interface. A propulsion unit (4) is mounted under the cab. The frame front also supports impact-absorbing buffers designed to undergo plastic deformation in two stages (9,10), an underslung cow-catcher (5) and an automatic coupling (8) with its own impact absorber (11). The whole extension is enclosed in a removable fairing (7), flush-fitting to the main vehicle body.
Patent DE-69819029-T2 (DE)
Inventor: SMITH PETER
IPC: F23D3/02
Filed: 1998-10-26
Granted: 2004-07-08
Abstract: An apparatus and method are provided, which enable an air modifying agent such as an insecticide, pesticide, insect repellant, fragrance, perfume etc. to be disseminated into an atmosphere. The air modifying agent is entrained in a flammable liquid carrier (2) which is less volative than the agent, which is held in a container (1). A wick (3) draws the agent/carrier (2) up to an igniting station provided at the rim (5) of a metal collar (4) which closely encircles the wick (3). The collar (4) is provided with a pair of diametrically opposed elongate slots (8), which expose part of the wick (3) to the atmosphere and thereby provide a vaporisation station spaced below the igniting station and disposed in the path of the flammable liquid carrier. In use, heat from a flame (6) passes along the collar (4) and warms the wick (3) in the vaporisation station, thereby assisting the preferential evaporation of the air modifying agent from the vaporisation station, away from the flammable liquid carrier prior to the latter's combustion in the flame (6). An angled deflecting plate (10) is also provided to deflect the evaporated air modifying agent away from the flame (arrow A).
Patent DE-69821469-T2 (DE)
Inventor: GELOTTE M
IPC: A61K31/58
Filed: 1998-02-04
Granted: 2004-12-23
Abstract: A novel process has been developed for the treatment of crosslinked ethylene-propylene diene monomer (EPDM) elastomer material to decrease its residual peroxide levels. EPDM is used to form the seats and neck gaskets of metering valves used in metered-dose inhalers (MDI). For filled and inverted MDI units these EPDM components are in direct contact with the pharmaceutical formulation media. The process involves exposing the EPDM valve components to a solution of 2-mercaptoethanol, a chemical reducing agent. The 2-mercaptoethanol greatly diminishes the residual peroxide levels in EPDM by reducing the peroxide functional groups to the corresponding hydroxyl groups. EPDM components treated in this manner have demonstrated very low peroxide levels and, consequently, greatly improved compatibility with the pharmaceutical formulation in the inhaler. An advantage of this approach is that the treated EPDM would likely retain its favorable physical properties and its good performance in metering valves. In this work 2-mercaptoethanol was used as the model reducing agent. It is believed, however, that similar positive results can be obtained using other reducing agents, notably other volatile compounds containing sulfur in one of its lower valence states (i.e. other thiol compounds or sulfur dioxide).
Patent DE-69827614-T2 (DE)
Inventor: STOBIE ALAN
IPC: A61P25/02
Filed: 1998-02-24
Granted: 2005-11-10
Abstract: The present invention provides a substantially pure compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof, together with compositions containing, uses of, processes for the preparation of and intermediates used in the preparation of such compounds.
Patent DE-69910920-T2 (DE)
Inventor: MIETTINEN ERKKI
IPC: G05F1/56
Filed: 1999-07-23
Granted: 2004-07-22
Abstract: A control circuit for controlling a semiconductor component (2) comprising an emitter (E), a collector (C) and a gate (G), the control circuit comprising a gate driver (GD) the output of which is connected to the gate (G) of the semiconductor component to be controlled. The control circuit further comprises a resistance coupling (1) where two series connections of a diode (V1, V2) and a resistor (R1, R2) are in an antiparallel connection and connected between the emitter (E) of the semiconductor component (2) and the zero potential (Com) of the gate driver (GD), and a feedback capacitor (C1) connected between the collector (C) of the semiconductor component (2) and the end of the resistance coupling (1) connected to the zero potential (Com) of the gate driver. <IMAGE>
Patent DE-69912622-T2 (DE)
Inventor: PORTER RAY
IPC: B60R19/04
Filed: 1999-07-27
Granted: 2004-11-11
Abstract: A bumper beam extension for a bumper beam having left and right bumper beam extensions and a method for manufacturing the bumper beam extensions to provide impact crush resistance is disclosed. The bumper beam extensions include an insert end contoured and sized to fit in the end of the bumper beam and a main body portion having substantially a rearwardly facing saddle shape that includes an upper wing and a lower wing joined at a bight section. The main body portion is blow molded to configure the bight section to taper from a preselected distance from a forward wall of the main body portion until it is face to face with the forward wall. For increased stiffness, the bumper beam may be welded to a frame of a vehicle.