baber/WOPTO huggingface dataset:
Patent JP-3188464-B2 (JP)
IPC: D21H17/00
Filed: 1993-08-20
Granted: 2001-07-16
Abstract: Disclosed is a process for making soft tissue paper which includes providing a dry tissue web and then applying a sufficient amount of a chemical papermaking additive from a thin film to the dry web. The chemical papermaking additives are added to the surface of the tissue paper to enhance properties of the paper such as strength, softener, absorbency, and/or aesthetics. The chemical papermaking additive application process includes the steps of diluting the chemical papermaking additive with a suitable solvent, applying the diluted chemical solution to a heated transfer surface, evaporating the solvent from the dilute solution to form a film, and then transferring the film to the tissue by contacting the dry tissue web with the heated transfer surface. Preferably, the tissue web is dried to a moisture level below its equilibrium moisture content before application of the papermaking additive.
Patent JP-4122061-B2 (JP)
IPC: C07K14/635
Filed: 1997-08-01
Granted: 2008-07-23
Abstract: This invention describes analogues of human parathyroid hormone which have increased activities in bone restoration, and increased bioavailabilities. The peptides described are derivatives of hPTH-(1-31) which are cyclized for example, by formation of Lactams between either Glu<22> and Lys<26> or Lys<26> and Asp<30>. In addition, the natural Lys<27> may be substituted by either a Leu or other hydrophobic residues, such as Ile, norleucine, Met, Val, Ala, Trp, or Phe. Typically, these analogues have enhanced abilities to stimulate adenylyl cyclase in rat osteosarcoma cells, and show increased activities in bone restoration, using the ovariectomized rat model. The analogues also show enhanced activities and bioavailabilities, as demonstrated by their hypotensive effects in the rat. An assay which correlates hypotensive activity with osteogenic activity is also described.
Patent JP-3140465-B2 (JP)
IPC: A61K9/22
Filed: 1993-09-10
Granted: 2001-03-05
Abstract: A sustained-release hydrogen preparation comprising at least one drug, an additive for making water penetrate into the preparation and a macromolecular substance which forms hydrogel. It can nearly completely gel when it stays in the upper parts of the digestive tract, i.e. the stomach and small intestine, and can release the drug in the lower part thereof, i.e. the colon. The preparation enables the drug to be well dissolved and absorbed even in the colon, thus achieving a stable sustained-release effect.
Patent JP-3734264-B2 (JP)
IPC: C08L63/00
Filed: 1994-10-20
Granted: 2006-01-11
Abstract: PCT No. PCT/AT94/00154 Sec. 371 Date Jun. 19, 1995 Sec. 102(e) Date Jun. 19, 1995 PCT Filed Oct. 20, 1994 PCT Pub. No. WO95/11272 PCT Pub. Date Apr. 27, 1995A halogen-free resin mixture comprising an epoxy resin, a hardener, a flame retardant as well as additives, a self-extinguishing prepreg composed of this resin mixture as well as its advantageous application, particularly as an insulation material. The halogen-free resin mixture being composed of: a) 20-60 weight % epoxy resin; b) 20-60 weight % phenolic novolak hardener; c) 5-65 weight % zinc borate as flame retardant; and d) 0-30 weight % additives.
Patent JP-3139766-B2 (JP)
IPC: A61K31/557
Filed: 1991-06-11
Granted: 2001-03-05
Abstract: The invention relates to the use of alcohol derivatives of F-type prostaglandins as ocular hypotensives. The PGF derivatives used in accordance with the invention are encompassed by the following structural formula (I)  <IMAGE>  wherein wherein wavy line attachments indicate either the alpha ( alpha ) or beta (b) configuration; hatched lines indicate  alpha  configuration, solid triangles are used to indicate b configuration, dashed bonds represent a double bond, the 5,6-double bond being in cis-configuration, or a single bond; R is hydrogen or a -(CO)R4 group; R1, R2, and R3 independently are hydroxyl, or -O(CO)R5 groups, wherein R4 and R5 independently stand for saturated or unsaturated acyclic hydrocarbon having from 1 to 20 carbon atoms, or -(CH2)nR6 where n is 0-10 and R6 is an aliphatic, aromatic or heteroaromatic ring, R7 and R8 independently are hydrogen or alkyl of one to 6 carbon atoms or pharmaceutically acceptable salts thereof.
Patent JP-4128629-B2 (JP)
IPC: F24C15/20
Filed: 1998-02-17
Granted: 2008-07-30
Abstract: A chamber serving for a heat treatment of a particular food product, which for example can be pre-processed potato pieces which are to be prepared as French fried potatoes, and therefore have a content of evaporable substances, such as fat. In the chamber is a grid for, during operation, carrying the product, and one or more quartz lamps for generating heat for the process. The chamber is furthermore fitted with an exhaust channel which via a filter device connects the chamber to the open. Above the grid is placed a cabinet which is open at the bottom, for mounting the quartz lamps. The cabinet is via an inlet duct connected to the open. In the inlet duct is placed a ventilator for sending an air flow into the cabinet via the inlet duct. The air acts as a shield which keeps for example fat vapors at a distance so that they cannot come into contact with the quartz lamps and disintegrate in the high temperature of these. Thereby, it is prevented that unhealthy and malodorous substances are produced during the process. The air shield furthermore cools the quartz lamps, which thereby will attain a long life.
Patent JP-4068155-B2 (JP)
IPC: C12N1/21
Filed: 1997-11-18
Granted: 2008-03-26
Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a Baccillus cell, wherein the mutant (i) comprises a first nucleic acid sequence encoding the polypeptide and a second nucleic acid sequence comprising a modification of at least one of the genes responsible for the biosynthesis or secretion of a surfactin or isoform thereof under conditions conducive for the production of the polypeptide and (ii) the mutant produces less of the surfactin or isoform thereof than the Bacillus cell when cultured under the same conditions; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to mutants of Bacillus cells and methods for producing the mutants.
Patent JP-3242664-B2 (JP)
IPC: B23B51/06
Filed: 1995-04-27
Granted: 2001-12-25
Abstract: PCT No. PCT/EP95/01600 Sec. 371 Date Oct. 15, 1996 Sec. 102(e) Date Oct. 15, 1996 PCT Filed Apr. 27, 1995 PCT Pub. No. WO95/29030 PCT Pub. Date Nov. 2, 1995A rotary drill comprising a shaft of full carbide metal which shaft is to be connected to the driving spindle of a machine tool. The shaft contains helically extending ducts which run adjacent to one another through the shaft, substantially longitudinally, for transporting cooling fluid to the cutting edge of the drill. At least two of the ducts are covered by a common sealing plate adjacent the cutting end of the shaft, with the sealing plate being a distance from the cutting edges of the drill, to create a closed fluid flow path between the ducts to permit dry operation of the drill.
Patent JP-3506715-B2 (JP)
IPC: B60K26/02
Filed: 1997-01-24
Granted: 2004-03-15
Abstract: The invention relates to a single-pedal system for controlling the speed of the engine and the braking effect in a motor vehicle. A pedal holder (1) is mounted for movement from a resting position for effecting braking of the vehicle. A pedal (3) is movably supported on the pedal holder (1) for controlling the speed of the engine of the vehicle. A returning means is arranged to return the pedal holder (1) to the resting position. A locking means (10) is arranged to hold, in a non-braking state of function of the system, the pedal holder (1) in its resting position and, when passing to a braking state of function of the system, to release the pedal holder (1) from the resting position if a compressive force exceeding a predetermined value is applied to the latter.
Patent JP-3996950-B2 (JP)
IPC: A61K35/12
Filed: 1995-04-28
Granted: 2007-10-24
Abstract: A method of inducing the proliferation and/or differentiation of human fetal pancreatic cells entails contacting such cells in primary culture with Hepatocyte Growth Factor/Scatter Factor, thereby inducing a proliferation of  beta -epithelial cells, an increase in the number of  beta -epithelial cells which form islet-like cell clusters, and an increase in insulin production per cell. The method provides increased numbers of functional islet-like cell clusters for transplantation, for example, into Type 1 diabetic patients. The method can be scaled up so as to provide clinically useful numbers of cells for transplantation.
Patent JP-4382877-B2 (JP)
IPC: C07K14/805
Filed: 1996-03-22
Granted: 2009-12-16
Abstract: A method for producing a stable polymerized hemoglobin blood-substitute from blood characterized in the use of a chromatographic column, is disclosed. The method of this invention includes mixing blood with an anticoagulant to form a blood solution, washing the red blood cells in the blood solution and then separating the washed red blood cells from the white blood cells. This method also includes disrupting the red blood cells to release hemoglobin and form a hemoglobin solution, which is then treated by high performance liquid chromatography to form a hemoglobin eluate. The hemoglobin eluate is then deoxygenated, contacted with a first reducing agent to form an oxidation-stabilized deoxygenated hemoglobin solution, and mixed with a cross-linking agent to form a polymerization reaction mixture, which is then polymerized. The polymerized hemoglobin solution is then diafiltered with a physiologic solution and with a reducing agent, whereby the polymerized hemoglobin solution is made physiologically acceptable, and whereby the reducing agent scavenges oxygen, to form a stable polymerized hemoglobin blood-substitute which is then packaged and stored in an atmosphere substantially free of oxygen. Compositions made by the methods are also disclosed, as are methods of therapeutically, or prophylactically, treating a vertebrate to increase tissue oxygenation, or prevent oxygen depletion, in tissue of the vertebrate.
Patent JP-4173539-B2 (JP)
IPC: A61K35/74
Filed: 1995-05-11
Granted: 2008-10-29
Abstract: PCT No. PCT/EP95/01778 Sec. 371 Date Nov. 10, 1997 Sec. 102(e) Date Nov. 10, 1997 PCT Filed May 11, 1995 PCT Pub. No. WO96/35782 PCT Pub. Date Nov. 14, 1996The invention relates to a nucleotide sequence, which is able to inhibit the IL-6 activity, its use in therapy as well as pharmaceutical compositions containing it. In particular, it relates to a nucleotide sequence which comprises: i) at least one nucleotide sequence that is an APRE element of general formula ZXMYKGKAA, wherein Z represents T or G or can also be absent, X represents T or can also be absent, M represents C or A, Y represents C or T and K represents T or G, in conjunction with ii) at least one nucleotide sequence constituting a transcription factor binding site other than the APRE element, such as those present in promoter regions.
Patent JP-4410849-B2 (JP)
IPC: G06F19/00
Filed: 1996-05-15
Granted: 2010-02-03
Abstract: A care management system in which the management of the administration of care for patients is automated. Hospital information systems are monitored and the information from those systems is used in verifying the administrations of care to patients. The care management system monitors ongoing administrations for progress and automatically updates records and provides alarms when necessary. The care management system is modular in nature but is fully integrated among its modules. Particular lists of data, such as the termination times of all ongoing infusions, provide hospital staff current information for increased accuracy and efficiency in planning. Features include the automatic provision of infusion parameters to pumps for accurate and efficient configuration of the pump, and providing an alarm when an unscheduled suspension of an infusion exceeds a predetermined length of time.
Patent JP-3991096-B2 (JP)
IPC: B01J3/02
Filed: 1997-04-15
Granted: 2007-10-17
Abstract: System for feeding a suspension, preferably a suspension of chips in a liquid carrier, to a pressurized vessel in a cellulose pulp mill, which system comprises at least one pump (25, 26) between a low-pressure part and the pressurized vessel for driving the suspension from the low-pressure part into the vessel, which pump is of the type which comprises a number of parallel discs (40, 42) which are held together to form a stack (39) and rotate in a pump chamber (36) in a pump housing about a common axis of rotation, with the spaces (46) between the discs being greater than the particles in the suspension, and with an axial inlet and a tangential outlet for the suspension. The invention also includes a pump and an apparatus unit which are intended to form part of the system.
Patent ES-2392411-B2 (ES)
Title: Método y sistema de detección de hidrocarburos basado en el análisis de datos SAR
Inventor: MERA PEREZ DAVID
IPC: G01N33/18
Filed: 2012-07-26
Granted: 2014-01-15
Abstract: Sistema y un método de detección automático de vertidos de hidrocarburos optimizado para dar una respuesta en tiempo casi real a la presencia de este tipo de vertidos en el océano. Para llevar a cabo la detección de los vertidos se emplea imágenes que proporcionan información de la radiación, en el rango de las microondas, reflejada por la superficie. Estas imágenes se analizan en un sistema informático y a partir de este análisis se genera una lista de zonas en las que se han producido vertidos de hidrocarburos.
Patent AU-2002252982-B2 (AU)
Title: Ternary mixtures of biodegradable polyesters and products manufactured from them
Inventor: GUANELLA ITALO
IPC: C09D167/04
Filed: 2002-01-25
Granted: 2006-06-29
Abstract: The invention relates to a mixture of biodegradable polyesters which includes an aromatic-aliphatic polyester (A), an aliphatic polyester (B) and a polylactic acid polymer (C) in which the concentration of A varies, with respect to (A+B) in the range between 40 and 70% by weight, and the concentration of C with respect to (A+B+C) is of between 6 and 30% by weight.
Patent AU-2002330343-B2 (AU)
Title: Method for sealing a plastic spout
Inventor: LAST LAURENS
IPC: B65D33/38
Filed: 2002-10-10
Granted: 2007-08-02
Abstract: A plastic spout (150,170) which is adapted to be sealed between two foil walls of a pouch. The spout has a spout body, which forms a passage (153) for delivering a medium from the pouch and/or feeding a medium to the pouch. 
In a bottom part thereof, the spout, on opposite sides, forms a sealing zone for a sealed connection to an adjoining foil wall. 
The sealing zones of the spout body are formed by sealing walls (158,159) which project downward from the spout body, each having a curvature over their entire length, such that each sealing wall is outwardly convex over its entire length with respect to an imaginary plane passing through the outermost ends, which adjoin one another, of the sealing walls. 
The sealing walls can preferably move flexibly transversely with respect to their plane and, on their inner side, are unsupported or are supported by one or more flexible supporting parts of the spout body.
Patent AU-2002335952-B2 (AU)
Title: Method of protein purification
Inventor: HAJ-AHMAD YOUSEF
IPC: C12P21/00
Filed: 2002-10-30
Granted: 2008-03-20
Abstract: Purification methods are provided for proteins and peptides, employing silicon carbide to bind the proteins or peptides. The methods may also be used to recover and purify recombinantly expressed proteins sequestered in inclusion bodies. The method for purifying a protein or peptide comprises contacting a solution containing the protein or peptide with silicon carbide at a binding pH for the protein or peptide to allow the protein or peptide to bind to the silicon carbide; and eluting the protein or peptide from the silicon carbide.
Patent AU-2002345965-B2 (AU)
Title: Artificial synapse chip interface for electronic prosthetic retina
Inventor: PETERMAN MARK
IPC: A61K9/22
Filed: 2002-06-25
Granted: 2006-09-14
Abstract: The invention provides microfabricated devices and methods for directing the growth of a cell process to form an artificial synapse. The devices are called artificial synapse chips. The artificial synapse comprises a nanofabricated aperture (about 50-100 nm in size) that connects the cell process to a chemical or electrical means of neuronal excitation. Such an aperture width mimics the length scales of a natural synapse and thus emphasizes the localized spatial relationship between a neuron and a stimulation source. The invention further provides devices and methods for regenerating a nerve fiber into an electrode. The invention thus provides a regeneration electrode that uses a novel neural interface for stimulation and that uses novel surface methods for directing neuronal growth making possible in vivo connection of the devices to neural circuitry in a retina and other anatomical locations.
Patent AU-2002350412-B2 (AU)
Title: Abin-mediated hepatitis protection
Inventor: DELAEI FILIP
IPC: A61K38/16
Filed: 2002-06-20
Granted: 2006-06-15
Abstract: The present invention relates to the use of the A20-binding inhibitor of NF-kappaB activation (ABIN), or a functional fragment or variant thereof to protect against TNF-induced liver failure, such as viral hepatitis and alcoholic liver disease. More particularly, it relates to the prevention of the toxic effects of said diseases, including lethality, by overexpressing ABIN.
Patent AU-2002357482-B2 (AU)
Title: Method for the production of desclarithromycin, and intermediate products
Inventor: KORB GERHARD
IPC: C07H/
Filed: 2002-11-02
Granted: 2009-03-26
Abstract: A novel method using novel intermediate products, suitable for advantageous production of desclarithromycin.
Patent AU-2003303495-B2 (AU)
Title: Reducing scale factor transmission cost for MPEG-2 AAC using a lattice
Inventor: VINTON MARK STUART
IPC: G10L19/02
Filed: 2003-12-16
Granted: 2009-02-19
Abstract: A perceptual encoder divides an audio signal into successive time blocks, each time block is divided into frequency bands, and a scale factor is assigned to each of ones of the frequency bands. Bits per block increase with scale factor values and band-to-band variations in scale factor values. A preliminary scale factor for each of ones of the frequency bands is determined, and the scale factors for the each of ones of the frequency bands is optimized, the optimizing including increasing the scale factor to a value greater than the preliminary scale factor value for one or more of the frequency bands such that the increase in bit cost of the increasing is the same or less than the reduction in bit cost resulting from the decrease in band-to-band variations in scale factor values resulting from increasing the scale factor for one or more of the frequency bands.
Patent AU-2004218239-B2 (AU)
Title: 5-phenylthiazole derivatives and their use as P13 kinase inhibitors
Inventor: BRUCE IAN
IPC: A61P11/06
Filed: 2004-03-05
Granted: 2007-02-22
Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Patent AU-2004219888-B2 (AU)
Title: Package comprising a detergent composition
Inventor: FREGONESE DANIELE
IPC: C11D17/00
Filed: 2004-03-11
Granted: 2008-05-15
Abstract: A package comprises a detergent composition enclosed by a water-soluble or water-dispersible packaging material. The detergent composition further comprises encapsulated phthalimidoperhexanoic acid (PAP) in granular form having a particle size of from 10-500 mum.
Patent AU-2004316069-B2 (AU)
Title: Stabilization with substituted ureas against color degradation of personal care products
Inventor: ZHANG JOANNA HONG
IPC: A61K8/36
Filed: 2004-12-03
Granted: 2007-10-11
Abstract: A personal care product is provided which includes an unsaturated organic material with at least one olefinic double bond susceptible to degradation into a color bearing substance, the unsaturated material being selected from C<SUB>10</SUB>-C<SUB>50 </SUB>terpenoids and C<SUB>12</SUB>-C<SUB>48 </SUB>unsaturated fatty compounds selected from the group consisting of fatty alcohols, fatty acids, fatty acid glycerides, fatty acid salts and combinations thereof, a substituted urea as a stabilization agent to prevent color body formation, and a cosmetically acceptable carrier. Particularly useful as a stabilizing agent is hydroxyethyl urea.
Patent AU-2005203240-B2 (AU)
Title: Phrase identification in an information retrieval system
Inventor: PATTERSON ANNA L
IPC: G06F40/00
Filed: 2005-07-25
Granted: 2009-01-22
Abstract: An information retrieval system uses phrases to index, retrieve, organize and describe documents. Phrases are identified that predict the presence of other phrases in documents. Documents are the indexed according to their included phrases. Related phrases and phrase extensions are also identified. Phrases in a query are identified and used to retrieve and rank documents. Phrases are also used to cluster documents in the search results, create document descriptions, and eliminate duplicate documents from the search results, and from the index.
Patent AU-2005230684-B2 (AU)
Title: Process and reagents for oligonucleotide synthesis and purification
Inventor: MUTHIAH MANOHARAN
IPC: C07D249/18
Filed: 2005-04-05
Granted: 2011-10-06
Abstract: The present invention relates to processes and reagents for oligonucleotide synthesis and purification. One aspect of the present invention relates to compounds useful for activating phosphoramidites in oligonucleotide synthesis. Another aspect of the present invention relates to a method of preparing oligonucleotides via the phosphoramidite method using an activator of the invention. Another aspect of the present invention relates to sulfur-transfer agents. In a preferred embodiment, the sulfur-transfer agent is a 3-amino­1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to a method of preparing a phosphorothioate by treating a phosphite with a sulfur-transfer reagent of the invention. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4­dithiazolidine-5-one. Another aspect of the present invention relates to compounds that scavenge acrylonitrile produced during the deprotection of phosphate groups bearing ethylnitrile protecting groups. In a preferred embodiment, the acrylonitrile scavenger is a polymer-bound thiol. Another aspect of the present invention relates to agents used to oxidize a phosphite to a phosphate. In a preferred embodiment, the oxidizing agent is sodium chlorite, chloroamine, or pyridine-N-oxide. Another aspect of the present invention relates to methods of purifying an oligonucleotide by annealing a first single-stranded oligonucleotide and second single-stranded oligonucleotide to form a double-stranded oligonucleotide; and subjecting the double-stranded oligonucleotide to chromatographic purification. In a preferred embodiment, the chromatographic purification is high­performance liquid chromatography.
Patent AU-2005244904-B2 (AU)
Title: Compounds and compositions for delivering active agents
Inventor: PUSZTAY STEPHEN V
IPC: A61K45/06
Filed: 2005-05-16
Granted: 2011-10-13
Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.