baber/WOPTO huggingface dataset:
Patent WO-2021137908-A1 (WO)
Title: Automatic focus detection with relative threshold-aware cell visibility for a scrolling cell collection
Inventor: NGUESSAN OLAYINKA SYLVIA
IPC: G06F3/0485
Filed: 2020-09-30
Abstract: A system and methods are disclosed for automatic focus detection with relative threshold-aware cell visibility for a scrolling cell collection. The method includes identifying visible cells of a plurality of cells of a reference frame, the visible cells rendered in a graphical user interface (GUI) displaying at least a portion of the reference frame, determining, by a processing device rendering the GUI and for each visible cell of the visible cells, a distance value indicating a distance to a focus threshold in the reference frame that the visible cell has traveled since the visible cell became visible in the GUI, and modifying a behavior of the visible cells in the GUI based on the distance value of each of the visible cells.
Patent WO-2021067627-A1 (WO)
Inventor: COLLINS THOMAS
IPC: A23L33/105
Filed: 2020-10-01
Abstract: Methods for converting mixtures of anthocyanins occurring in fruit or vegetable juice or extract into particular anthocyanin molecules having desirable colorant properties are provided herein. The method of the present disclosure can be employed to increase the amount of particular anthocyanin molecules, while lowering the total number of anthocyanin molecules present in the natural juice and/or extract. The disclosure is also directed to anthocyanin molecules prepared by the methods of present disclosure and to enzymes capable of catalyzing reactions that provide such effects.
Patent WO-2021072115-A1 (WO)
Title: Crispr-mediated human genome editing with vectors
Inventor: OU LI
IPC: C12N15/63
Filed: 2020-10-08
Abstract: Compositions and methods for Cas-based  ex vivo  and  in vivo  gene therapy applications are provided.
Patent WO-2021141650-A1 (WO)
Title: Methods and apparatuses for dynamic adaptive streaming over http
Inventor: SODAGAR IRAJ
IPC: H04N21/858
Filed: 2020-10-15
Abstract: Aspects of the disclosure provide methods, apparatuses, and a non-transitory computer-readable storage medium for receiving media data. One apparatus includes processing circuitry that receives a media presentation description (MPD) file in which an essential property descriptor includes an attribute indicating uniform resource locator (URL) information for a session-based description (SBD) file. The SBD file includes one or more groups of key-value pairs. The processing circuitry receives the SBD file based on the URL information. The processing circuitry sends a request to a server based on the SBD file.
Patent WO-2021086718-A1 (WO)
Title: Methods and apparatus providing calibration of background illumination for sample and/or sample container characterization
Inventor: CHANG YAO-JEN
IPC: G01N35/10
Filed: 2020-10-22
Abstract: A calibration method is provided including identifying the imaging area on each light panel with respect to each imaging device. A center position of the imaging area of each light panel for each imaging device is determined. An optimal optical center of the imaging apparatus using the center position of the imaging area of each imaging device is determined. A tube calibration tool is installed in a carrier on a track, and the carrier is moved on the track so that a center of the tube calibration tool is located at a closest location to the optimal optical center of the imaging apparatus. The center of the tube calibration tool is used to determine a center of a region of interest (ROI) for backlight calibration. Methods for heath checking the calibration and apparatus used to carry out the calibration are provided as well as other aspects.
Patent WO-2021081300-A1 (WO)
Title: Pigmented and scattering particles in side coating materials for led applications
Inventor: BASIN GRIGORIY
IPC: H01L33/44
Filed: 2020-10-23
Abstract: Phosphor-converted LED side reflectors disclosed herein comprise pigments that are photochemically stable under illumination by light from the pcLED. The pigments absorb light in at least a portion of the spectrum of light emitted by the first phosphor converted LED. The side reflector may also comprise light scattering particles or air voids. The pigments, light scattering particles, or air voids may be homogeneously distributed in the reflector. Alternatively the side reflector may be layered, with the pigments, light scattering particles, or air voids inhomogeneously distributed in the reflector. The side reflector can include phosphor particles.
Patent WO-2021133469-A1 (WO)
Inventor: AGRAWAL VARUN
IPC: G06F9/38
Filed: 2020-11-04
Abstract: An electronic device handles accesses of a branch prediction functional block when executing instructions in program code. The electronic device includes a processor having the branch prediction functional block that provides branch prediction information for control transfer instructions (CTIs) in the program code and a minimum predictor use (MPU) functional block. The MPU functional block determines, based on a record associated with a given fetch group of instructions, that a specified number of subsequent fetch groups of instructions that were previously determined to include no CTIs or conditional CTIs that were not taken are to be fetched for execution in sequence following the given fetch group. The MPU functional block then, when each of the specified number of the subsequent fetch groups is fetched and prepared for execution, prevents corresponding accesses of the branch prediction functional block for acquiring branch prediction information for instructions in that subsequent fetch group.
Patent WO-2021134091-A1 (WO)
Inventor: XU HUILIN
IPC: H04B7/06
Filed: 2020-11-23
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive scheduling information that schedules a physical downlink shared channel (PDSCH) communication for the UE; and select a downlink beam for reception of the PDSCH communication from a set of usable downlink beams associated with an uplink beam to be used by the UE for uplink transmission in one or more symbols in which the PDSCH communication is scheduled. Numerous other aspects are provided.
Patent WO-2022125129-A1 (WO)
Title: Emballage-coque de préparation d'échantillons
Inventor: HAINES PAUL MARK
IPC: C12Q1/6806
Filed: 2021-03-01
Abstract: L'invention concerne un emballage-coque de préparation d'échantillons qui peut comprendre une pluralité de réservoirs formés comme des coques. Les réservoirs peuvent comporter une couche barrière actionnable et une couche barrière d'étanchéité avec des contenus des réservoirs entre la couche barrière actionnable et la couche barrière d'étanchéité. Le contenu peut être destiné à faciliter l'isolement d'un composant biologique d'un échantillon biologique. Les réservoirs individuels peuvent être adaptés pour libérer le contenu à travers la couche barrière d'étanchéité lors de l'actionnement de la couche barrière actionnable. La coque peut avoir une largeur et une longueur, et les réservoirs peuvent être alignés le long de la longueur. Dans cet exemple, un premier réservoir contient un fluide mécanique inerte et un deuxième réservoir contient un réactif, un tampon ou une combinaison de ceux-ci.
Patent WO-2021183914-A1 (WO)
Inventor: YEO EUGENE
IPC: C12N9/22
Filed: 2021-03-12
Abstract: L'invention concerne des procédés d'utilisation de protéines chimériques pour produire des modifications d'ARN qui peuvent être détectées par des procédés de séquençage, y compris des procédés de détection de taux de traduction relatifs de divers ARNm. L'invention concerne également des compositions comprenant des protéines chimériques, les protéines chimériques comprenant une protéine d'édition d'ARN et une protéine ribosomale.
Patent WO-2021202351-A1 (WO)
Title: Methods and systems for detecting colorectal cancer via nucleic acid methylation analysis
Inventor: ST JOHN JOHN
IPC: G06N20/20
Filed: 2021-03-29
Abstract: The present disclosure provides methods and systems for screening or detecting a colorectal cancer or following colorectal disease progression that may be applied to cell-free nucleic acids such as cell-free DNA. The method may use detection of methylation signals within a single sequencing read in identified genomic regions as input features to train a machine learning model and generate a classifier useful for stratifying populations of individuals. The method may comprise extracting DNA from a cell-free sample obtained from a subject, converting the DNA for methylation sequencing, generating sequencing reads, and detecting colon proliferative cell disorder-associated signals in the sequencing information and training a machine learning model to provide a discriminator capable of distinguishing groups in a subject population such as healthy, cancer or distinguishing disease subtype or stage. The method may be used for, e.g., predicting, prognosticating, and/or monitoring response to treatment, tumor load, relapse, or colorectal cancer development.
Patent WO-2021207701-A1 (WO)
Inventor: NEUMANN CHRISTOPHER SCOTT
IPC: A61P35/00
Filed: 2021-04-09
Abstract: The present disclosure provides,  inter alia , ADCs with charge variant chemical linkers useful in treating various diseases such as cancer and autoimmune disorders.
Patent WO-2021222702-A1 (WO)
Inventor: LAFRANCE DANNY
IPC: C07D311/30
Filed: 2021-04-30
Abstract: Disclosed are crystalline forms of the compound of formula (I). Also disclosed are compositions containing the crystalline forms of the compound of formula (I) and methods of their use. The methods may be for modulating a metabolic marker or a nonalcoholic fatty liver disease marker in a subject in need thereof, e.g., by administering to the subject an effective amount of the crystalline form disclosed herein or its composition. The methods may be for treating a metabolic disorder or nonalcoholic fatty liver disease in a subject in need thereof, e.g., by administering to the subject an effective amount of the crystalline form disclosed herein or its composition.
Patent WO-2022015392-A1 (WO)
Title: Probabilistic text index for semi-structured data in columnar analytics storage formats
Inventor: WEN JIAN
IPC: G06F16/81
Filed: 2021-04-30
Abstract: Herein is a probabilistic indexing technique for searching semi-structured text documents in columnar storage formats such as Parquet, using columnar input/output (I/O) avoidance, and needing minimal storage overhead. In an embodiment, a computer associates columns with text strings that occur in semi-structured documents. Text words that occur in the text strings are detected. Respectively for each text word, a bitmap, of a plurality of bitmaps, that contains a respective bit for each column is generated. Based on at least one of the bitmaps, some of the columns or some of the semi-structured documents are accessed.
Patent WO-2021231552-A1 (WO)
Title: Compositions and methods for controlling blood pressure
Inventor: HODGKINSON CONRAD
IPC: C12N15/90
Filed: 2021-05-12
Abstract: The present disclosure describes compositions and methods for treating hypertension in a subject.
Patent WO-2021237074-A1 (WO)
Inventor: HOPKINS TIMOTHY P
IPC: A43B13/20
Filed: 2021-05-21
Abstract: L'invention concerne des structures de semelle (104), des systèmes de support de pied (400, 420, 440), des articles de chaussures (100) et/ou d'autres dispositifs de réception de pied comprenant des chambres de vessie remplies de fluide en communication fluidique les unes avec les autres, et dans lesquelles un fluide est mobile entre les chambres pour induire une inclinaison de pied, par exemple, une inclinaison d'avant-pied. Ces éléments peuvent comprendre : (a) une première chambre de vessie de support de pied latérale (400M) ; (b) une seconde chambre de vessie de support de pied latérale (400L) ; (c) un système de régulation de débit de fluide (500) comprenant un premier orifice (502A) et un second orifice (502B), le système de régulation de débit de fluide (500) déplaçant un fluide à travers chacun d'un premier trajet d'écoulement de fluide et d'un second trajet d'écoulement de fluide ; (d) une première conduite de fluide (402M) reliant le premier orifice (502A) à la première chambre de vessie de support de pied latérale (400M) ; et (e) une seconde conduite de fluide (402L) reliant le second orifice (502B) à la seconde chambre de vessie de support de pied latérale (400L). Dans le premier trajet d'écoulement de fluide, le fluide se déplace : (a) à partir de la première chambre de vessie de support de pied latérale (400M), (b) à travers la première conduite de fluide (402M), (c) à travers le premier orifice (502A), (d) à travers le système de régulation de débit de fluide (500) jusqu'au second orifice (502B), (e) à travers le second orifice (502B), (f) à travers la seconde conduite de fluide (402L), et (g) dans la seconde chambre de vessie de support de pied latérale (400L). Dans le second trajet d'écoulement de fluide, le fluide se déplace : (a) à partir de la seconde chambre de vessie de support de pied latérale (400L), (b) à travers la seconde conduite de fluide (402L), (c) à travers le second orifice (502B), (d) à travers le système de régulation de débit de fluide (500) jusqu'au premier orifice (502A), (e) à travers le premier orifice (502A), (f) à travers la première conduite de fluide (402M), et (g) dans la première chambre de vessie de support de pied latérale (400M).
Patent WO-2021242989-A1 (WO)
Title: Compositions and methods for inducing cas9 protein expression by use of autonomous pd-1 promoter activity
Inventor: ITO FUMITO
IPC: C12N9/14
Filed: 2021-05-27
Abstract: Modified eukaryotic cells that contain a DNA sequence comprising a drug inducible Cre-recombinase expression system, a sequence encoding a Cas9 enzyme, and a conditional promoter that becomes operably linked to the sequence encoding the Cas9 enzyme by function of the Cre-recombinase system, are provided. The disclosure further provides compositions comprising the modified cells and methods of administering the modified cells to an individual in need thereof.
Patent WO-2022015464-A1 (WO)
Title: Influencer tools for stream curation based on follower information
Inventor: OSMAN STEVEN
IPC: G06Q30/02
Filed: 2021-06-17
Abstract: Methods and systems are provided for recommending content channels for an influencer. The method includes identifying a session of the influencer. The session includes a current content channel being viewed by the influencer and made available for streaming to one or more followers of the influencer. The current content channel is one of a plurality of content channels made available for viewing by the influencer. The method includes accessing, during the session, content data from the plurality of content channels. The content data is associated with gameplay of one or more players engaged in gameplay. The method includes accessing profile data of the followers of the influencer. The profile data includes content preferences of said followers. The method includes predicting engagement metrics for said followers of the influencer in relation to said plurality of content channels. The engagement metrics are updated in substantial real time based on change occurring with the content data in plurality of content channels. The method includes generating an influencer interface for presenting said predicted engagement metrics. The engagement metrics are configured to provide indicators of when engagement metrics for the current content channel indicate a predicted decrease relative to a predicted increase when switching to a different content channel from among the plurality of content channels available during the session.
Patent WO-2022006045-A1 (WO)
Title: Choke system with capacity for passage of large debris
Inventor: SUNDARARAJAN ALAGARSAMY
IPC: E21B34/04
Filed: 2021-06-29
Abstract: Embodiments include a choke system that passes enlarged debris despite having a relatively small diameter for an input port of the choke system. Embodiments also include systems to prevent dislodging of a choke seat when backpressure is supplied to the choke system. Embodiments also include sealing systems to prevent fluid leaks around the choke seat of the choke system.
Patent WO-2022026297-A1 (WO)
Inventor: WILDRIDGE MATT
IPC: A61F2/07
Filed: 2021-07-22
Abstract: The present embodiments provide systems and methods for improved retention of stents on a delivery system. In one embodiment, a delivery system comprises a catheter and a balloon. A proximal end of the balloon is secured to an exterior surface of the catheter at a first location, and a distal end of the balloon is secured to the exterior surface of the catheter at a second location. A plurality of bands are disposed in a circumferential space situated between the exterior surface of the catheter and an interior surface of the balloon. The plurality of bands may comprise at least two bands that are discretely spaced-apart in an axial direction from one another along a length of the catheter. At least one stent is secured to the exterior surface of the balloon in a compressed delivery state.
Patent WO-2022047159-A1 (WO)
Title: Adaptive memory refresh control
Inventor: KIM KANG-YONG
IPC: G11C11/4076
Filed: 2021-08-27
Abstract: Systems, apparatuses, and methods related to a memory device and an associated host device are described. The memory device (104) and the host device (102) can include control logic (112, 118) that allow the memory device and host device to share refresh-timing information, which may allow either the memory device or the host, or both, to manage operations during time that is dedicated to, but unused for, refresh or self-refresh operations. Refresh-timing information shared from the host device may indicate elapsed time since the host device issued a refresh command to the memory device and/or how much time remains before the host device is scheduled to issue another refresh command. Refresh-timing information shared from the memory device may indicate elapsed time since the memory device performed a self-refresh operation and/or how much time remains before the memory device is scheduled to initiate or undergo another self-refresh operation.
Patent WO-2022051564-A1 (WO)
Title: Multi-layered thermal insulation system for battery pack temperature retention
Inventor: TAXAK MANISH
IPC: B32B5/02
Filed: 2021-09-03
Abstract: An insulation material having three or more layers, the layers including a metallic facing; and one or more nonwoven layers. One or more of the layers may be a needlepunched layer. Each nonwoven layer may have a temperature resistance of about 400 °C or greater. The insulation material may be used for surrounding and insulating a battery, such as a battery for an electric vehicle.
Patent WO-2022060854-A1 (WO)
Title: Programming of regulatory t cells by extracellular vesicles
Inventor: KANDEEL FOUAD
IPC: C12N5/0783
Filed: 2021-09-15
Abstract: Provided herein, inter alia, are compositions and methods for reprogramming immune cells for treating or preventing immune disorders. The methods include contacting immune cells with antigens, and administering the resultant immune cells to a subject who has an immune disorder.
Patent WO-2022087366-A1 (WO)
Title: Système de chauffage de réservoir de fluide d'échappement diesel
Inventor: ROCKEY SHAWN AARON
IPC: F01N3/20
Filed: 2021-10-22
Abstract: Systèmes et appareils comprenant un réservoir de fluide d'échappement diesel, un premier capteur de température positionné à l'intérieur du réservoir de fluide d'échappement diesel et structuré pour fournir de premières informations de température indicatives d'une première température, et un second capteur de température positionné à l'intérieur du réservoir de fluide d'échappement diesel et structuré pour fournir de secondes informations de température indicatives d'une seconde température. Les systèmes et les appareils comprennent en outre un ou plusieurs circuits de traitement comprenant un ou plusieurs dispositifs de mémoire couplés à un ou plusieurs processeurs, le ou les dispositifs de mémoire étant configurés pour stocker des instructions sur celui-ci qui, lorsqu'ils sont exécutés par le ou les processeurs, amènent le ou les processeurs à fournir de l'énergie à un système de chauffage sur la base des premières informations de température et des secondes informations de température.
Patent WO-2022115445-A1 (WO)
Title: Ballonnet d'artère périphérique, hypo-tube de préparation de ballonnet d'artère périphérique et ses méthodes d'utilisation
Inventor: Mustapha Jihad Ali
IPC: A61M25/10
Filed: 2021-11-23
Abstract: L'invention concerne un ballonnet d'artère périphérique comprenant une extrémité distale ayant un premier diamètre externe, une extrémité proximale ayant un second diamètre externe plus grand que le premier diamètre externe, et une partie d'étendue qui s'étend de l'extrémité distale à l'extrémité proximale, la partie étendue ayant un diamètre externe qui va en augmentant progressivement du premier diamètre externe de l'extrémité distale au second diamètre externe de l'extrémité proximale. L'extrémité distale, l'extrémité proximale et la partie étendue du ballonnet d'artère périphérique sont dimensionnées pour imiter un diamètre variable d'une artère naturelle. La divulgation concerne également un hypo-tube de préparation de ballonnet d'artère périphérique, ainsi qu'une méthode de remodelage et/ou de traitement d'artères après une athérectomie et/ou pendant une angioplastie à l'aide d'un ballonnet d'artère périphérique.
Patent WO-2022119810-A1 (WO)
Inventor: EHSANI FARZAD
IPC: A61B5/0205
Filed: 2021-11-30
Abstract: A system for management of health conditions, such as mental health conditions, using a biosensor configured to monitor one or more biological properties of an individual and providing feedback and information based on data in real-time. A corresponding method, performed by one or more components of the system, may include monitoring a biological property of the individual, identifying an irregularity as a symptom of the health condition, and intervening with the individual to alleviate the symptom. The method may further include determining an efficacy of the intervention and adapting the method to improve the intervention. The system may be configured to predict a future symptom and preventatively intervene.
Patent WO-2022132547-A1 (WO)
Inventor: HARTKOP DAVID
IPC: H02K1/16
Filed: 2021-12-09
Abstract: A permanent magnet synchronous motor that is well suited for electric vehicles. The motor's rotor (3) comprises a ring-shaped permanent magnet (4) array that rotates within a stator (2) comprising outer stator core 22 and inner stator core 24 and top and bottom stator end caps defining an interior circular tunnel-like volume there between bounded by cylindrical walls. The stator contains a circular array of solenoidal coils (1 ) each coil filling a slot set into the internal walls of the inner and outer stator cores and the inner surfaces of the top and bottom caps of the stator. Mechanical power developed in the rotor (3) is transmitted to an output shaft (11) by a belt (8) and pulley (10). The motor has improved electromotive efficiency over prior art because the entirety of each field coil is electromagnetically involved in producing torque. In addition, use of belt (8) reduces vibration and eliminates the need for sealed lubrication required when working with gears.