baber/WOPTO huggingface dataset:
Patent CA-2588401-C (CA)
Inventor: DELUCA HECTOR F
IPC: A61P29/00
Filed: 2005-11-18
Granted: 2013-02-12
Abstract: This invention discloses 17(20)-dehydro-vitamin D analogs, and specifically 17(Z)-1.alpha.,25-dihydroxy-17(20)-dehydro-2-methylene-19-nor-vitamin D3 and pharmaceutical uses therefor. This compound has use as an anti-cancer agent, in the treatment of skin diseases and skin conditions and in the treatment of autoimmune disorders and inflammatory diseases as well as renal osteodystrophy and obesity. The compounds have the formula I: (see formula I) where Y1 and Y2 are each hydrogen or a hydroxy protecting group, where R11 and R12 are each hydrogen, where R6 and R7 are hydrogen, alkyl, hydroxyalkyl, fluoroalkyl, hydroxy or alkoxy, or R6 and R7 when taken together may represent the group -(CH2)x-where x is an integer from 2 to 5, or R6 and R7 when taken together may represent the group =CR8R9 where R8 and R9 are hydrogen, alkyl, hydroxyalkyl, fluoroalkyl, hydroxy or alkoxy, or when taken together R8 and R9 may represent the group -(CH2)x- where x is an integer from 2 to 5, and where the group R represents typical side chains known for vitamin D type compounds.
Patent CA-2590224-C (CA)
Title: Method for reduction, stabilization and prevention of rupture of lipid rich plaque
Inventor: KOBAYASHI HIDEYUKI
IPC: A61K31/47
Filed: 2005-12-09
Granted: 2011-12-20
Abstract: There is to provide is an agent for reduction of a lipid rich plaque, stabilization of a lipid rich plaque and/or prevention of rupture of a lipid rich plaque in an atherosclerotic lesion comprising an effective amount of 2-[4-[2-(benzimidazole-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamide (hereinafter, referred to as compound 1), its pharmaceutically acceptable salt or a hydrate thereof and Pitavastatin, and a pharmaceutically acceptable carrier, wherein the agent is intended to be simultaneously administered, or separately administered with interval of time to a patient in need thereof. There is also to provide a method for reduction of a lipid rich plaque, stabilization of a lipid rich plaque and/or prevention of rupture of a lipid rich plaque in an atherosclerotic lesion, comprising simultaneously administering, or separately administering with interval of time an effective amount of the compound 1, its pharmaceutically acceptable salt or a hydrate thereof and an effective amount of Pitavastatin to a patient in need thereof.
Patent CA-2595334-C (CA)
Inventor: BRAUN DORIS
IPC: A61P25/18
Filed: 2006-01-27
Granted: 2016-08-23
Abstract: The present invention relates to novel polymorphic forms of aripiprazole and processes for producing them. It further relates to pharmaceutical compositions comprising the novel forms and to the use of the novel forms in the treatment of schizophrenia.
Patent CA-2595610-C (CA)
Title: Anticorps diriges contre l'angiopoietine 2 et leurs utilisations
Inventor: GREEN LARRY L
IPC: C07K14/475
Filed: 2005-12-19
Granted: 2013-03-05
Abstract: La présente invention a trait à des anticorps dirigés contre l'angiopoïétine 2 et à des utilisations de tels anticorps, notamment, des anticorps monoclonaux entièrement humains dirigés contre l'antigène angiopoïétine 2, à des séquences nucléotidiques codant pour, et à des séquences d'acides aminés comportant, des molécules d'immunoglobuline à chaînes lourdes et légères, en particulier des séquences correspondant aux séquences à chaînes lourdes et chaînes légères contiguës recouvrant des régions charpente et/ou des régions déterminant de la complémentarité, spécifiquement depuis la région charpente 1 jusqu'à la région charpente 4 ou depuis la région 1 déterminant de la complémentarité jusqu'à la région 3 déterminant de la complémentarité, à des hybridomes ou autres lignées cellulaires d'expression de telles molécules d'immunoglobuline et de tels anticorps monoclonaux.
Patent CA-2597177-C (CA)
Inventor: MAHER JONATHAN SCOTT
IPC: G01N33/53
Filed: 2007-08-14
Granted: 2012-01-31
Abstract: Disclosed is a diagnostic testing device that may be used to detect one or more analytes in a sample. The device comprises a receptacle and a holder for a test strip. The test strip may be, for example, a lateral flow test strip. The device and holder permit analysis of a sample, wherein the device is substantially sealed during testing and detection of results. To use, the holder containing a test strip is inserted into the receptacle containing sample to be analyzed. Capillary flow along the test strip is initiated by contact of the sample with the distal end of the test strip. The receptacle is such that results of the assay may be detected visually or using standard instrumentation such as by measuring light absorption or reflectance.
Patent CA-2597893-C (CA)
Title: Compression tool jaw set
Inventor: HAMM JAMES E
IPC: B25B27/10
Filed: 2006-02-15
Granted: 2011-11-22
Abstract: A compression tool having a pair of jaw arms (12) pivotal between side plates (14, 16) and having inner edges (34) provided with laterally inwardly open opposed spring pin recesses (40) providing an opening therebetween for a spring pin (42), and a spring (48) associated with the pin and biasing the jaw arms in a closing direction and biasing the spring pin rearwardly of the spring pin opening has one or the other or both the spring pin opening and spring pin modified for the pin to be displaced from the spring pin opening or canted therein in response to a fracture of at least one of the jaw arms outwardly from the corresponding pin recess toward the outer edge (32) of the jaw arm.
Patent CA-2602256-C (CA)
Inventor: SOLIMAN SAMIR S
IPC: H04B1/7073
Filed: 2006-03-27
Granted: 2012-04-24
Abstract: L'invention concerne un procédé et un appareil pouvant produire et exploiter un signal de référence de localisation de position qui permette à un récepteur de recevoir des signaux de localisation de position de générateurs de signaux relativement faibles lorsqu'il est en présence d'une source de signaux forts. Les signaux de référence de localisation de position émanant de plusieurs sources peuvent être synchronisés de façon à survenir dans un intervalle de temps prévu d'un système de communication multiplexé par répartition dans le temps. Au cours de l'intervalle de temps prévu, chaque source de signaux peut configurer une émission comprenant une adresse de contrôle d'accès aux supports correspondant à une valeur réservée pour des signaux de localisation de position. Chaque source de signaux configure l'émission de façon à comprendre un signal de référence de localisation de position correspondant à la source de signaux. Les signaux de localisation de position provenant de chaque source de signaux sont positionnés de façon à survenir en un moment de la partie de données de l'intervalle de temps prévu, de sorte qu'aucune source de signaux voisine ne transmette son signal de localisation de position correspondant.
Patent CA-2614219-C (CA)
Title: Feuilles perforees presentant des fentes diagonales avec orifices d'absortion incurves pour digesteur
Inventor: SHEERER JAY K
IPC: D21D5/02
Filed: 2007-12-13
Granted: 2016-04-12
Abstract: Une feuille perforée est destinée à un récipient dextraction de matière cellulosique, la feuille perforée comportant une pluralité de fentes qui traversent la feuille perforée et ont des rebords de coin dentrée courbés sur la surface intérieure de la feuille perforée. La surface intérieure de la plaque perforée fait face à l'écoulement de la pâte à lintérieur du récipient à pâte. La largeur des fentes est telle que les fibres dans l'écoulement de pâte sont retenues dans le récipient à pâte.
Patent CA-2618349-C (CA)
Title: Dispositif et procede d'administration de medicament par voie intravesicale
Inventor: LEE HEEJIN
IPC: A61K9/00
Filed: 2006-08-11
Granted: 2016-05-31
Abstract: L'invention concerne des dispositifs de type implants pour l'administration par voie intravésicale et la distribution locale de médicament. Le dispositif de l'invention comprend : un corps qui comporte un tube creux formé par un matériau biocompatible ; au moins un réservoir dans le tube qui contient un médicament ; et une ou plusieurs ouvertures à travers lesquelles le médicament peut être libéré. Le dispositif est conçu pour une insertion à effraction minimale dans une cavité corporelle, par exemple la vessie. Le tube creux peut être un tube élastomère pour permettre au dispositif d'être déformé de manière élastique de façon à passer de sa forme initiale à une forme allongée en vue d'être introduit dans un cathéter, le dispositif pouvant retrouver sa forme initiale après l'introduction dans un cathéter de manière à être retenu plus facilement dans ladite cavité corporelle. Le corps du dispositif peut présenter une forme allongée et étroite permettant d'insérer ledit dispositif de distribution de médicament dans un cathéter sans être déformé, et comprend également des parties saillantes flexibles qui assurent sa rétention dans ladite cavité corporelle.
Patent CA-2620348-C (CA)
Inventor: MARTINAK LEONARD
IPC: F16K31/363
Filed: 2006-08-24
Granted: 2009-11-10
Abstract: A valve actuator comprising a lower housing comprising a mounting spool that is operable to couple to a valve body. A rotating sleeve is disposed within the lower housing and coupled to a stem connector. A fixed sleeve in disposed within the lower housing and includes a first slot disposed therethrough. A  second slot is disposed in the rotating sleeve, wherein at least one of the slots is a helical slot. An axle engages both the first slot and the second slot. A shaft is coupled to the axle and extends through a connector flange that is coupled to an upper end of the lower housing. A piston is coupled to the shaft and movably disposed within an upper housing that is coupled to the connector flange. Axial movement of the piston within the upper housing will result in rotational movement of the rotating sleeve.
Patent CA-2630068-C (CA)
Title: Locking clutch for downhole motor
Inventor: UNDERWOOD LANCE D
IPC: F16D43/14
Filed: 2008-04-28
Granted: 2011-06-21
Abstract: A locking clutch to selectively transmit torque from a stator of a downhole tool to a rotor of the downhole tool includes at least one locking pawl disposed upon the rotor, wherein the at least one locking pawl comprises a load path, a pivot axis, and a mass center, wherein the at least one locking pawl is biased into an engaged position by a biasing mechanism, wherein the at least one locking pawl transmits force from the stator to the rotor along the load path when in the engaged position, and wherein centrifugal force urges the at least one locking pawl into a disengaged position when the rotor is rotated above a disengagement speed.
Patent CA-2634131-C (CA)
Inventor: WARNE NICHOLAS W
IPC: C07K16/24
Filed: 2006-12-21
Granted: 2014-02-11
Abstract: Protein formulations and methods for reducing the viscosity of a protein formulation are provided. The method for reducing the viscosity of a protein formulation comprises adding a viscosity reducing agent, such as calcium chloride or magnesium chloride to the protein formulation.
Patent CA-2634790-C (CA)
Inventor: BROWN RAWLIN HEATH
IPC: G02B3/00
Filed: 2008-06-10
Granted: 2016-07-26
Abstract: An optical system includes a lens cell having a generally cylindrical lens cell body. The lens cell body has a lens cell central longitudinal axis and a lens cell optical axis eccentrically offset from the lens cell central longitudinal axis. A sleeve includes a generally cylindrical sleeve body having an outer surface with a first longitudinal axis and an inner surface with a second longitudinal axis eccentrically offset from the first longitudinal axis. The lens cell is inserted into the sleeve. A housing has a generally cylindrical body with the sleeve at least partially inserted into the housing. A clip is disposed about at least a portion of the circumference of the housing. The lens cell and the sleeve are rotated relative to each other and to the housing such that the lens cell optical axis is aligned in a desired location. After the lens cell optical axis is aligned in the desired location, the clip is releasably coupled to and inserted through the housing and into the sleeve to restrict rotation of the sleeve relative to the housing.
Patent CA-2636168-C (CA)
Title: Auxiliary water tank and pump assembly for a vehicle
Inventor: LINDBLOM THOMAS G
IPC: B28C7/14
Filed: 2006-11-02
Granted: 2010-07-06
Abstract: A self-purging auxiliary fluid supply system for supplying washout or makeup water or other fluids under pressure to a truck-mounted concrete mixing/dispensing drum is disclosed. The system includes a truck-mounted fluid reservoir for containing a quantity of fluid connected to supply fluid to an air-operated diaphragm pump connected to supply auxiliary fluid from the fluid reservoir under pressure to a discharge assembly. The pump further provides an integral purge system for displacing fluid in the fluid supply system after use.
Patent CA-2638690-C (CA)
Title: Electrolytes, cells and methods of forming passivation layers
Inventor: CHEN ZONGHAI
IPC: H01M4/587
Filed: 2008-08-18
Granted: 2014-12-23
Abstract: An electrolyte comprising at least one salt of the formula: Li2B12F x Z12-x wherein x is at least 5 but less than or equal to 12 and Z represents H, ethylene carbonate (EC), ethylmethyl carbonate (EMC), and lithium difluoro(oxalate) borate.
Patent CA-2647867-C (CA)
Inventor: KAJIHARA YASUHIRO
IPC: C07K1/113
Filed: 2007-03-28
Granted: 2015-11-03
Abstract: The present invention provides a process for producing a peptide thioester compound, characterized by comprising: (A) forming a peptide by a solid-phase synthesis method using a resin modified with a linker represented by the formula (1) as a solid phase; (B) cleaving a bond between the solid phase and the peptide with at least one acid selected from dilute hydrochloric acid, dilute sulfuric acid, formic acid, and acetic acid to produce a peptide having a carboxyl group at the C-terminus; and (C) reacting a thiol compound with the peptide at -100 to 0°C in the presence of a condensing agent in a solvent: (1) wherein R1 represents C1-4 alkyl group, R2 represents hydrogen atom or C1-4 alkoxy group, and n represents an integer of 1 to 4.
Patent CA-2659837-C (CA)
Inventor: ABE NORIYUKI
IPC: F16H49/00
Filed: 2007-08-03
Granted: 2011-11-15
Abstract: To provide a magnetic power transmission system which is capable of improving the power transmitting efficiency and the power transmitting capacity while maintaining the advantageous effects obtained by performing power transmission by magnetic forces, and reducing manufacturing costs of the system. A magnetic power transmission system 1 is comprised of an outer rotor 11 including a plurality of circumferentially arranged left and right permanent magnets 11c, an inner rotor 12 including a plurality of circumferentially arranged left and right permanent magnets 12c, and an intermediate rotor 13 including a plurality of circumferentially arranged left and right soft magnetic material elements 13d, 13e. When each of the left and right permanent magnets 11c and 11c and each permanent magnet 12c are in an opposed position opposed to each other, if the magnetic pole of the left permanent magnet 11c and the magnetic pole at the left-side end of the permanent magnet 12c have polarities different from each other, the magnetic pole of the right permanent magnet 11c and the magnetic pole at the right-side end of the permanent magnet 12c have the same polarity. Further, when one of the soft magnetic material elements 13d and 13e is between permanent magnets 11c and 12c, the other is between two permanent magnets 11c and 12c adjacent to each other.
Patent CA-2661942-C (CA)
Inventor: SMITH WILLIAM G
IPC: C02F3/12
Filed: 2007-09-24
Granted: 2012-12-04
Abstract: Introducing a combination of suspended attached growth Medias and biological reactants into a sewage treatment process with or without additional reaction to improve and increase capacity of a given process. Media and biological reactants can be disposed in a perforated container or flexible container that can be submerged in a sequencing bed reactor or the aeration and/or mixing tanks of an activated sludge sewage treatment process.
Patent CA-2666753-C (CA)
Title: Mountable safe
Inventor: KALOUS D SCOTT
IPC: E05B67/36
Filed: 2007-10-31
Granted: 2012-05-29
Abstract: A portable safe for assembly with an apertured member includes a safe housing and a safe door. The safe housing has an internal cavity extending to an access port, and at least one opening configured to align with at least one aperture of the apertured member. The safe door is securable to the housing to substantially block the access port. The safe door includes a locking mechanism having at least one locking member secured in a housing engaging position when the locking mechanism is in a locked condition. The at least one locking member is movable to a housing disengaging position when the locking mechanism is in an unlocked condition. The safe door further includes a lock interface that is selectively operable to move the locking mechanism from the locked condition to the unlocked condition.
Patent CA-2667637-C (CA)
Title: Proteines de fusion comprenant une cytokine anti-inflammatoire et un antigene destinees au traitement de troubles immunitaires
Inventor: MANNIE MARK D
IPC: A61P37/02
Filed: 2007-10-29
Granted: 2021-04-20
Abstract: La présente invention porte sur des protéines de fusion comprenant un antigène auto-immun, un antigène allergène ou un allo-antigène, et une cytokine anti-inflammatoire. L'invention porte également sur des compositions et des procédés comprenant les protéines de fusion.
Patent CA-2670329-C (CA)
Title: Settings emulator for a circuit interrupter trip unit and system including the same
Inventor: CARLINO HARRY J
IPC: H01H71/74
Filed: 2009-06-26
Granted: 2015-12-15
Abstract: A settings emulator for a circuit breaker trip unit includes a handheld enclosure and a plurality of adjustable rotary switches mounted on the handheld enclosure. The adjustable rotary switches define a plurality of different trip settings for the circuit breaker trip unit. A communication channel is also mounted on the handheld enclosure. A microprocessor is enclosed by the handheld enclosure. The processor reads the different trip settings from the adjustable rotary switches and communicates the different trip settings through the communication channel to the circuit breaker trip unit.
Patent CA-2671713-C (CA)
Title: Systeme de catheter orientable
Inventor: OLSEN DANIEL
IPC: A61M25/01
Filed: 2006-12-07
Granted: 2014-09-09
Abstract: L'invention concerne des dispositifs pour naviguer à travers les passages situés dans un corps, et en particulier un cathéter orientable (630) pouvant être utilisé pour naviguer à travers l'anatomie tortueuse d'une vascularisation corporelle. Dans un mode de réalisation de l'invention, le cathéter déformable comprend un corps de cathéter intérieur (611) ayant un premier élément d'épine dorsale de support (615), et un second élément de queue de support en porte-à-faux (614). Un corps de cathéter extérieur (607) est associé en coopération avec le second élément de queue de support, et un actionneur (606) est associé en coopération avec le premier élément d'épine dorsale de support. L'actionneur est mis en prise de manière coulissante dans le corps de cathéter extérieur.
Patent CA-2673125-C (CA)
Title: Compositions et procedes d'inhibition de la voie jak
Inventor: LI HUI
IPC: A61K31/505
Filed: 2007-10-19
Granted: 2015-04-21
Abstract: L'invention concerne des composés représentés par la formule I et les compositions et procédés utilisant ces composés dans le traitement d'états dans lesquels la modulation de la voie JAK ou l'inhibition de kinases JAK est thérapeutiquement utile.
Patent CA-2676831-C (CA)
Title: Oil scavenge system having churning damper for gas turbine engines
Inventor: ALECU DANIEL T
IPC: F01D25/18
Filed: 2008-03-19
Granted: 2011-07-12
Abstract: An oil scavenge system of a gas turbine engine in accordance with one embodiment of the present invention, comprises a housing (32) defined about an axis of rotation, the housing (32) confining an air/oil mixture in motion within the housing (32) and defining an oil scavenge area (46) below the axis of rotation. The housing (32) further includes an outlet (48) at a low location of the housing (32). A churning damper (40) is supported within the housing (32) and is located in the oil scavenge area (46). The churning damper (40) includes at least one plate (42), allowing the air/oil mixture in motion to pass over or through the plate (42) only in a peripheral area of the at least one plate (42) to cause flow energy dissipation.
Patent CA-2679771-C (CA)
Title: Procede de production d'hydrogene avec captation totale du co2 et recyclage du methane non converti
Inventor: FISCHER BEATRICE
IPC: C01B3/02
Filed: 2009-09-25
Granted: 2017-03-21
Abstract: La présente invention concerne un procédé de production d'hydrogène à partir d'une charge hydrocarbonée et de vapeur d'eau comprenant : - une étape de production d'un gaz de synthèse dans une unité de vaporéformage de la charge hydrocarbonée en présence de la vapeur d'eau, un combustible apportant la chaleur nécessaire à la réaction, - une étape de conversion à la vapeur du gaz de synthèse obtenu à l'étape précédente produisant un flux d'hydrogène contenant du méthane et du dioxyde de carbone, - une étape de captage du dioxyde de carbone présent dans le flux obtenu à l'étape de conversion à la vapeur permettant de séparer le dioxyde de carbone du flux d'hydrogène, - une étape de captage et de recyclage vers le vaporéformage du méthane et d'autres impuretés (CO,CO2) présentes dans le flux d'hydrogène.
Patent CA-2682389-C (CA)
Inventor: ALEXANDER CLAYTON
IPC: F21V29/50
Filed: 2007-11-02
Granted: 2015-06-30
Abstract: A lighting assembly and a method for manufacturing a lighting assembly are provided. The lighting assembly includes a light module including a lighting element, and an enclosure having a recess for receiving and housing the light module. The lighting assembly also includes a thermally conductive core connected to the light module through the enclosure. The lighting assembly further includes a housing mounted in thermal contact with the core and the enclosure, so as to cause the housing to dissipate heat to an ambient atmosphere.
Patent CA-2686458-C (CA)
Title: Systems and methods for providing delayed signals
Inventor: WILENS DAVID
IPC: H03K5/14
Filed: 2008-05-22
Granted: 2016-07-19
Abstract: A variable delay apparatus comprises a calibrating unit receiving a signal from a variable delay unit (101) and from a plurality of fixed delay sources (401, 402, 403), the calibrating unit comparing the signal from the variable delay unit (101) with a plurality of signals from the fixed delay sources (401, 402, 403) to control operation of the variable delay unit (101) over a delay range independently of environmentally-induced drift.
Patent CA-2700349-C (CA)
Inventor: REID JACQUELINE
IPC: C10L10/18
Filed: 2008-09-25
Granted: 2016-08-23
Abstract: A diesel fuel composition comprising a performance enhancing additive, wherein the performance enhancing addi-tive is the product of a Mannich reaction between: (a)an aldehyde; (b)a polyamine; and (c)an optionally substituted phenol; wherein the polyamine component (b) includes the moiety R1 R2 NCHR3 CHR4 NR5 R6 wherein each of R1, R2 R3, R4, R5 and R6 is indepen-dently selected from hydrogen, and an optionally substituted alkyl, alkenyl, alkynyl, aryl, alkylaryl or arylalkyl substituent.
Patent CA-2704868-C (CA)
Title: Alkylcellulose and salt compositions for dust control applications
Inventor: BYTNAR STEPHEN C
IPC: C08K3/16
Filed: 2010-05-20
Granted: 2017-04-25
Abstract: A method of reducing dust generation from an aggregate surface is described. The method includes applying a dust suppression compound to the aggregate surface. The dust suppression compound may be made from an aqueous mixture of an alkylcellulose compound and a halogen containing salt.