baber/WOPTO huggingface dataset:
Patent AU-2021201486-A1 (AU)
Title: A method to produce an immunoglobulin preparation with improved yield
Inventor: BRUCKSCHWAIGER LEOPOLD
IPC: C07K1/36
Filed: 2021-03-09
Abstract: OF THE DISCLOSURE 
The present invention provides improved methods for the manufacturing of 
IVIG products. These methods offer various advantages such as reduced loss of IgG during 
purification and improved quality of final products. In other aspects, the present invention 
provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, 
and/or intramuscular administration. In yet other embodiments, the present invention 
provides methods of treating a disease or condition comprising administration of an IgG 
composition provided herein.
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Patent AU-2021204709-A1 (AU)
Title: Composite thin wingbox architecture for supersonic business jets
Inventor: BEHZADPOUR FOROUZAN
IPC: B64C3/20
Filed: 2021-07-06
Abstract: COMPOSITE THIN WINGBOX ARCHITECTURE FOR SUPERSONIC 
BUSINESS JETS 
ABSTRACT 
An apparatus including one or more panels including an outer face sheet comprising a plurality 
of first composite materials; an inner face sheet comprising a plurality of second composite 
materials; and a plurality of foam pieces disposed between the outer face sheet and the inner face 
sheet, wherein the foam pieces reduce warping of the panels.
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Patent AU-2021211978-A1 (AU)
Title: Atmospheric corrosion monitoring device and method based on optical fiber surface plasmon resonance
Inventor: FU GUANGWEI
IPC: G01N21/552
Filed: 2021-08-02
Abstract: Disclosed herein is an atmospheric corrosion monitoring device and method based on 
optical fiber surface plasmon resonance. The device includes: a light source, a fiber optic 
sensor, and an optical spectrum analyzer are sequentially connected by an optical fiber 
5 jumper; the fiber optic sensor is an optical fiber corrosion sensor based on surface plasmon 
resonance, and comprises a sensing optical fiber and a metal film, and a polishing area is 
provided on one side of an outer surface of a cladding of the sensing optical fiber, and the 
metal film is coated on the polishing area; a weakly acidic atmosphere outside will corrode 
the metal film and change the thickness of it, a resonance wavelength of an optical fiber 
0 surface plasmon resonance sensor will drift, and, in a certain range of the thickness of the 
metal film, a change in the thickness of the metal film has a linear relation with the resonance 
wavelength drift. Calculating the resonance wavelength drift rate to reflect the corrosion rate 
of the metal film, then the atmospheric corrosion detection is achieved. The present invention 
solves the problems of long detection period and incapability of real-time monitoring in the 
5 prior art, and has the advantages of high sensitivity and real-time monitoring.
fiber optic sensor 4 6 
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Patent AU-2021211980-A1 (AU)
Title: Methods, tools, and tool assemblies for biomolecular analysis using microarrays
Inventor: RAJASEKARAN JOHN J
IPC: G01N35/10
Filed: 2021-08-02
Abstract: Disclosed herein are methods, tools, pillar plates, and tool assemblies for biomolecular 
analysis using microarrays that reduces the likelihood of air bubbles being trapped by the 
microarrays. Embodiments of the tools include two clamps that have a tool mount portion 
and a grasping portion. The tool mount portion is configured to engage a lifting mechanism 
of a plate handling robot for moving a pillar plate that include microarrays. The grasping 
portion is configured to freely suspend the pillar plate at an inclination of a non-zero tilt angle 
relative to a plane normal to the tool mount portion. Embodiments of pillar plates include two 
protruding edges on opposite sides of the pillar plate and a plurality of pillars with one or 
more affixed microarrays. Embodiments of the tool assembly include the tool and the pillar 
plate, wherein the protruding edges are configured to engage with the grasping portions.
Patent AU-2021217399-A1 (AU)
Title: Methods and use for bioengineering enucleated cells
Inventor: KLEMKE RICHARD
IPC: A61K9/127
Filed: 2021-02-05
Abstract: Provided are methods for treating a disease using bioengineered enucleated cells. Also provided herein are compositions comprising enucleated cells, wherein the enucleated cells have been loaded with clinically relevant biomolecules.
Patent AU-2021217512-A1 (AU)
Title: Method and device for automated operation of a plant for storing bulk material
Inventor: ESSER PHILIPP
IPC: B65G3/02
Filed: 2021-01-25
Abstract: In a method and a device for operating a plant for storing bulk material, the plant comprising at least one stockpile-like storage region, in particular a facility for transloading materials or a material recovery plant, a digital stockpile model is in particular created for the at least one storage region and, on the basis of the created stockpile model, the development of physical and/or chemical states, which may occur during storage of the respectively stored material, is predicted, and the predicted physical and/or chemical states are used as reference during storage operation in order to ensure material-preserving storage of the stored material.
Patent AU-2021218411-A1 (AU)
Title: Gene therapy vectors for treating heart disease
Inventor: LOMBARDI LAURA
IPC: A61P9/00
Filed: 2021-02-11
Abstract: The present disclosure provides methods and compositions useful for the treatment or prevention of heart disease. In particular, the present disclosure provides a vector comprising a modified troponin T promoter operatively linked to a therapeutic gene product for the treatment or prevention of heart disease,
Patent AU-2021223500-A1 (AU)
Title: An adaptor for a medical container and a medical container comprising said adaptor
Inventor: EUVRARD NICOLAS
IPC: A61J1/20
Filed: 2021-02-16
Abstract: An adaptor for a medical container and a medical container comprising said adaptor The present invention relates to an adaptor (1) for connecting a medical container to a connector, the adaptor (1) comprising longitudinal projections (5) comprising a distal portion (6) configured to exert a progressively increasing radial pressure on connecting means of the connector when said connector is moved axially proximally within the adaptor (1) and a proximal portion (7) configured to authorize the partial release of said pressure as the connector is moved further proximally, said proximal portion (7) being further configured to be contacted by said connecting means upon said partial release of said pressure and to emit a sound when contacted by said connecting means, thereby providing an end user with a tactile and audible indication that the connection between the connector and the adaptor (1) is secured. The invention also relates to a medical container having such an adaptor mounted onto its distal tip.
Patent AU-2021225492-A1 (AU)
Title: Micellar disinfectants
Inventor: BOZA TRONCOSO AMERICO C
IPC: A01N59/00
Filed: 2021-02-26
Abstract: The present disclosure relates to micellar compositions conformed by biomimetic phospholipids and nonionic surfactants, among other ingredients, for eliminating one or more types of microorganisms including mycobacteria, bacteria, fungi, and viruses from a surface within a contact time on the surface of less than about 1 minutes and having pH of from about 0.3 to 8. The present invention aims on using 100% bio-based (renewable) biodegradable, non-toxic ingredients to be applied not only to hard inanimate surfaces but also on tissue for endodontic applications.
Patent AU-2021240109-A1 (AU)
Title: Self-propelled sprayer suspension travel reduction mechanism
Inventor: WUBBEN THOMAS M
IPC: B62D3/14
Filed: 2021-09-27
Abstract: An agricultural vehicle suspension may comprise a spring and a first spindle operably 
coupled with the spring in a spindle axial direction. A stop body may be operably coupled to the 
first spindle in a cylinder axial direction. The stop body may be configured to limit an axial 
length of travel of the suspension relative to the first spindle. The first spindle may be a steering 
spindle or a suspension spindle.  
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Patent AU-2021256385-A1 (AU)
Title: A system for ensuring failsafe operation of pitot tube covers for multiple types of pitot tubes
Inventor: DEGROFF STEVEN A
IPC: B64F1/00
Filed: 2021-03-29
Abstract: The present invention is directed to multiple arrangements of a self-disengaging pitot tube cover, which can be triggered by a plurality of different environmental conditions while the cover admits to a plurality of different latching mechanisms and opening configurations to guarantee the expeditious, automatic removal of the pitot tube cover while avoiding damage or contamination of the pitot tube itself.
Patent AU-2021263028-A1 (AU)
Title: Electrolyte compositions for rechargeable metal halide battery
Inventor: KIM JANGWOO
IPC: H01M6/16
Filed: 2021-03-31
Abstract: A rechargeable metal halide battery with an optimized electrolyte formulation shows high capacity at fast charging rates. The optimized electrolyte includes a metal halide, an oxidizing gas, and a mixed-solvent solution that includes a glyme-based compound that is in a volume fraction of between 20-70 volume % of the mixed-solvent solution. The mixed-solvent solution may further include a nitrile compound and/or a heterocyclic compound.
Patent AU-2021270839-A1 (AU)
Title: Formulations of anti-IL-33 antibodies
Inventor: EKIZOGLOU SOFIA
IPC: A61P11/06
Filed: 2021-05-10
Abstract: The present disclosure is directed to compositions comprising greater than about 100 mg/ml of an anti- IL-33 antibody, a surfactant, arginine and a buffer. Methods for making the compositions and methods of treating disease in a subject are also disclosed.
Patent AU-2021281828-A1 (AU)
Title: Anti-human NR1 antibody derivative
Inventor: KUBO SATOSHI
IPC: C12N15/63
Filed: 2021-05-26
Abstract: The present invention addresses the problem of providing a novel therapeutic agent for treating patients with anti NMDAR encephalitis.　Patients with anti NMDAR encephalitis have pathogenic anti-human NR1 antibody that induces internalization of NMDAR on cell surface. As a result, NMDAR function is weakened in the patients' brain. The present inventors found that the one-armed anti-human NR1 antibody according to the present invention binds to NR1 competitively with the pathogenic anti-human NR1 antibody and inhibits the internalization of NMDAR by the pathogenic anti-human NR1 antibody to thereby exhibit therapeutic effect on anti NMDAR encephalitis.　Accordingly, the present invention provides the one-armed anti-human NR1 antibody, a polynucleotide encoding the antibody, an expression vector containing the polynucleotide, a host cell transformed by the expression vector, a method for producing the antibody, a pharmaceutical composition comprising the antibody, use of the antibody in the production of the pharmaceutical composition, and a method for treating anti NMDAR encephalitis using the antibody. Selected drawing: none
Patent AU-2021286169-A1 (AU)
Title: RNA replicon for versatile and efficient gene expression
Inventor: PERKOVIC MARIO
IPC: C12N9/12
Filed: 2021-06-01
Abstract: The present invention embraces an RNA replicon (self-amplifying RNA vector (saRNA)) that can be replicated by a replicase of a self-replicating virus, e.g., a replicase of alphavirus origin. According to the invention, translation of the replicase open reading frame is uncoupled from a 5'-terminal cap by placing translation of the replicase open reading frame under the translational control of an internal ribosome entry site (IRES). Thereby the initiation of translation depends on the molecular properties of the respective IRES, which compared to cap-dependent translation may require less or no cellular initiation factors to direct the ribosome to the translational start site. According to the invention, IRES-controlled replicase translation may allow the use of uncapped synthetic saRNA. Furthermore, the use of an IRES provides for the option to insert additional transgenes upstream to the IRES.
Patent AU-2021299200-A1 (AU)
Title: Processes for making SERD tricyclic compounds having a substituted phenyl or pyridinyl moiety
Inventor: ZHANG HAIMING
IPC: C07D209/16
Filed: 2021-06-28
Abstract: Provided herein are processes for the preparation of intermediate compounds of formula (II) and of compounds of formula (I) which are useful in the treatment of cancer.
Patent AU-2021314398-A1 (AU)
Title: Use of perlecan and fragments thereof to reduce the risk of death in stroke patients
Inventor: ADKISSON IV HUSTON DAVIS
IPC: A61K38/20
Filed: 2021-07-26
Abstract: The present disclosure is directed to the use of perlecan compositions to reduce the risk of mortality in subjects due to neurological injury such as stroke, including large vessel occlusion, and traumatic brain injury. The disclosure is also directed to the use of perlecan compositions to reduce mortality in stroke patients treated with tPA.
Patent AU-2021327032-A1 (AU)
Title: Apparatus for an electronically-enabled board game
Inventor: THOMSON STEPHEN JOHN
IPC: A63F3/00
Filed: 2021-08-11
Abstract: The present invention provides an apparatus for an improved board game combining the advantages of both traditional and electronic games. The apparatus comprises a game board and a plurality of game pieces, wherein the apparatus is configured to detect the identity and location of a given game piece on the game board; and a server communicable with the game board and configured to receive information on the identity and location of the game pieces relative to the game board, and, if appropriate, send to the game board a display instruction, wherein the game board is configured to, in response to the display instruction, electronically display a game progress indicator.
Patent AU-2021327782-A1 (AU)
Title: Functional ionizable phospholipids
Inventor: SIEGWART DANIEL J
IPC: A61K31/7088
Filed: 2021-08-23
Abstract: Ionizable phospholipids and compositions and methods relating thereof are provided herein. In some aspects, the ionizable phospholipids provided herein may be formulated in compositions which contain a nucleic acid and one or more helper excipients. In some aspects, these compositions may also be used to treat diseases or disorders with a therapeutic nucleic acid.
Patent AU-2021332775-A1 (AU)
Title: Therapeutic agent for motor complications in parkinson's disease
Inventor: KURITA MITSUMASA
IPC: A61K31/198
Filed: 2021-08-30
Abstract: The present disclosure provides a therapeutic agent useful for the treatment of motor fluctuations (e.g., wearing-off) in Parkinson's disease. In particular, the present disclosure provides: a composition characterized by containing tandospirone or a pharmaceutically acceptable salt or prodrug thereof for treating, ameliorating, inhibiting the progression of, or preventing motor complications, particularly, motor fluctuations, of Parkinson's disease; and a method characterized in that the tandospirone or the pharmaceutically acceptable salt thereof is parenterally administered.
Patent AU-2021333871-A1 (AU)
Title: Method and apparatus for removing an article from a tray
Inventor: BAIR MATTHEW
IPC: B65G47/38
Filed: 2021-08-24
Abstract: A de-traying method and apparatus for removing articles from trays, is useful with a plurality of trays. The article is detrayed at the detraying assembly by elevating the moveable bottom of the tray at least to the level of the tray rim with an article lifter from below the tray. The article lifter includes a lifting base and a plurality of lifting blocks fixed to the lifting base. The lifting blocks are sized and arranged to engage the tray bottom through the opening in response to the lifting base being elevated. The lifting blocks are sized and arranged to maintain orientation of the tray with at least one of said blocks positioned outside of the tray adjacent the rim. The article is displaced off of the elevated tray bottom.
Patent AU-2021394454-A1 (AU)
Title: Connector assembly for furniture
Inventor: ASQUITH WARREN
IPC: F16B12/20
Filed: 2021-08-24
Abstract: A connector assembly (8) for use in furniture to hold a first panel (6) adjacent to a second panel (7). The connector assembly (8) including a body (9) for fixing to the first panel (6), a base (10) for fixing to the second panel (7), an actuator (11) including a drive surface (35) that interacts with a contact surface (36) on either one of the base (10) or the body (9) so that rotation of the actuator (11) about an actuator axis towards a secure position causes the drive surface (35) to slide over the contact surface (36) producing a camming action to draw the base (10) and the body (9) together.
Patent AU-2021405066-A1 (AU)
Title: Antibody variable domains and antibodies having decreased immunogenicity
Inventor: JOHANSSON MARIA
IPC: C07K16/46
Filed: 2021-12-23
Abstract: The present invention relates to antibody variable domains, which exhibit a reduced binding to pre-existing anti-drug antibodies (ADA), and to antibodies comprising one or more of said antibody variable domains. The present invention further relates to nucleic acid sequences encoding said antibody variable domains or said antibodies, vector(s) comprising said nucleic acid sequences, host cell(s) comprising said nucleic acids or said vector(s), and a method of producing said antibody variable domains or said multispecific antibodies. Additionally, the present invention relates to pharmaceutical compositions comprising said antibodies and to methods of use thereof.
Patent AU-2021411495-A1 (AU)
Title: Cd8 polypeptides, compositions, and methods of using thereof
Inventor: BAJWA GAGAN
IPC: C12N15/867
Filed: 2021-12-28
Abstract: The present disclosure relates to T cells capable of co-expressing T cell receptors ("TCR") together with CD8 polypeptides and the use thereof in adoptive cellular therapy. The present disclosure further provides for modified CD8 sequences, vectors, and associated methods thereof.
Patent AU-2022200184-A1 (AU)
Title: Washing machine and control method of washing machine
Inventor: JANG JAEHYUK
IPC: H05B6/10
Filed: 2022-01-13
Abstract: A washing machine includes: a tub configured to contain water; a drum of metal material 
configured to rotate in the tub; at least one temperature sensor configured to detect a 
temperature of air between the drum and the tub; an induction heater configured to be 
disposed in a position spaced apart from the drum and heat the drum; a controller unit 
configured to control the induction heater within a preset control temperature range based on 
a temperature detected by the at least one temperature sensor; a circuit configured to supply 
power to the induction heater; a first thermostat configured to operate according to the 
temperature of a first air between the drum and the tub, and open the circuit when the 
temperature of the first air is a first safety control temperature corresponding to a case where 
the temperature of the drum is in a first safety temperature range; and a thermal fuse 
configured to operate according to a temperature of the second air outside the tub, and open 
the circuit when the temperature of the second air is a second safety temperature 
corresponding to a case where the temperature of the drum is in a second safety temperature 
range having a larger value than the first safety temperature range.
Patent AU-2022200722-A1 (AU)
Title: Fitting structure
Inventor: TAWADA KAZUHIRO
IPC: F16B5/06
Filed: 2022-02-03
Abstract: A fitting structure for fitting a first member and a second member together, the fitting 
structure comprising: a fitting projection protruding from a second member opposed surface 
of the first member opposed to the second member toward the second member; a receptacle 
protruding from an opposite surface of the second member on an opposite side from the 
second member opposed surface in an opposite direction from the second member opposed 
surface, the receptacle including an internal receiving space communicating with a through 
hole in the second member, wherein the receptacle including: a fitting portion having a plate 
shape protruding from the opposite surface; a supporting portion protruding from the opposite 
surface such that at least a section of an inner surface of the supporting portion is opposed to 
an inner surface of the fitting portion; and two slits provided between two edges of the fitting 
portion extending in a protruding direction in which the fitting portion protrudes and edges of 
the supporting portion adjacent to the edges of the fitting portion, respectively, the slits 
communicating with the receiving space, the receiving space is defined by the fitting portion 
and the supporting portion, the fitting projection includes a first section disposed in the 
receiving space and a second section fitted to the fitting portion, the fitting projection further 
includes a fitting portion opposed surface being along the protruding direction and including a 
section opposed to the fitting portion, a supporting portion opposed surface being along the 
protruding direction and including a section opposed to the supporting portion, a surface 
extending between one edge of the fitting portion opposed surface and one edge of the 
supporting portion opposed surface and along the protruding direction, and a rib protruding 
from the surface in a direction along the second member opposed surface and being 
connected with the second member opposed surface.
Patent AU-2022201586-A1 (AU)
Title: Transcatheter valve devices and systems
Inventor: RAJAGOPAL VIVEK
IPC: A61B17/08
Filed: 2022-03-08
Abstract: A medical assembly for endovascularly implanting a valve in the heart having a valve and a 
valve delivery system for implanting and securing the valve. The valve delivery system 
introduces and seals the valve at the deployment site.
Patent AU-2022203322-A1 (AU)
Title: Improved methods of assessing UCH-L1 status in patient samples
Inventor: DATWYLER SAUL
IPC: G01N33/573
Filed: 2022-05-17
Abstract: Disclosed herein are improved methods of assessing ubiquitin carboxy-terminal 
hydrolase Li (UCH-LI) status in a subject (such as for example, as a measure of traumatic brain 
injury or for other clinical reasons). Also disclosed herein are methods of assessing a subject's 
glial fibrillary acid protein (GFAP) and UCH-L1 status in subject (such as, for example as a 
measure of traumatic brain injury or for other clinical reasons).
Patent AU-2022203866-A1 (AU)
Title: Internal ultraviolet therapy
Inventor: REZAIE ALI
IPC: A61B5/00
Filed: 2022-06-03
Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to 
treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has 
traditionally been used to treat skin disorders and for focused ablation of plaques in the 
arteries and other targeted internal uses, it has not been developed for broader infection, 
inflammation or neoplasia treatment inside the human body. Here, the inventor(s) developed 
a system for emission of therapeutic doses of UV light via a catheter, capsule, endoscope, 
tube or port that can be used to manage internal infections and inflammatory conditions 
inside a patient.