Patent SG-11201809051Y-A (SG)
Title: Cell retention device and method
Inventor: Coffman jonathan
IPC: C12M1/00
Filed: 2017-04-13
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 111110111011110 1111111111 010 MN III International Bureau 0.. .... .. (10) International Publication Number ...... ... (43) International Publication Date WO 2017/180814 Al 19 October 2017(19.10.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C12M 1/00 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, PCT/US2017/027318 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, 13 April 2017 (13.04.2017) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language: English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (26) Publication Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data: ZA, ZM, ZW. 62/322,825 15 April 2016 (15.04.2016) US 62/330,912 3 May 2016 (03.05.2016) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) (72) Applicant: BOEHRINGER INGELHEIM INTERNA- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TIONAL GMBH [DE/DE]; Binger Strasse 173, 55216 In- TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, gelheim am Rhein (DE). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Inventors (for US only): COFFMAN, Jonathan; c/o VP, IP Legal, Boehringer Ingelheim USA Corp., 900 Ridge- LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, bury Rd., P.O. Box 368, Ridgefield, Connecticut 06877- 0368 (US). GODFREY, Scott; c/o VP, IP Legal, GW, KM, ML, MR, NE, SN, TD, TG). Boehringer Ingelheim USA Corp., 900 Ridgebury Rd., Declarations under Rule 4.17: P.O. Box 368, Ridgefield, Connecticut 06877-0368 (US). — as to applicant's entitlement to apply for and be granted a WANG, Samantha; c/o VP, IP Legal, Boehringer Ingel- heim USA Corp., 900 Ridgebury Rd., P.O. Box 368, patent (Rule 4.17(ii)) Ridgefield, Connecticut 06877-0368 (US). Published: Agents: DATLOW, Philip I. et al.; Boehringer Ingelheim — with international search report (Art. 21(3)) (74) Pharmaceuticals, Inc., 900 Ridgebury Road, P.O. Box 368, Ridgefield, CT 06877-0368 (US). 1-1 7r 11 GC © GC 11 IN 1-1 (54) Title: CELL RETENTION DEVICE AND METHOD 0 ei (57) : The subject technology relates to a cell retention device and method for use in a perfusion cell culture system where en. ) the cell retention device includes a hollow-fiber filter having an average pore size ranging from about 0.5 to about 20 um and having ,7 1 ,1 9 the ability to operate under perfusion cell culture conditions for up to 35 days without being clogged or losing its product sieving ability by more than 20%.