baber/WOPTO huggingface dataset:
Patent WO-2021050380-A1 (WO)
Inventor: JUDSON JARED ALDEN
IPC: A61M5/315
Filed: 2020-09-04
Abstract: Des dispositifs d'administration de médicament comprennent une partie ensemble aiguille et une partie dispositif pour médicament, la partie ensemble aiguille pouvant être accouplée de manière amovible à la partie dispositif pour médicament. Dans certains modes de réalisation, l'aiguille de l'ensemble aiguille peut être déplacée entre une position rétractée et une position étendue pour percer la peau d'un sujet.
Patent WO-2021050431-A1 (WO)
Title: Supercritical hydrocyclotron and related methods
Inventor: LOOP THOMAS E
IPC: C10G9/20
Filed: 2020-09-08
Abstract: A supercritical hydrocyclotronic method is disclosed for transforming one or more selected polymeric materials into a plurality of reaction products via supercritical or near-supercritical water reaction that enable the rapid and economic conversion of solid biomass and/or waste plastic materials (i.e., organic materials) into smaller liquid and gaseous hydrocarbon molecules – smaller hydrocarbon molecules that, in turn, are useful as chemical feedstock materials including, for example, liquid transportation fuels and bio-adhesives. The innovative supercritical hydrocyclonic systems and related mobile units disclosed herein comprise, in combination, (1) a supercritical water (or near-supercritical water) treatment system for converting organic materials into smaller hydrocarbon molecules, and (2) a hydrocyclonic separation system for recovering the smaller hydrocarbon molecules from the combined water/hydrocarbon effluent.
Patent WO-2021071638-A1 (WO)
Title: Fragment size characterization of cell-free dna mutations from clonal hematopoiesis
Inventor: JIANG TINGTING
IPC: C12Q1/6869
Filed: 2020-09-16
Abstract: Methods and systems are provided for differentiating between cancer variants and somatic variants originating from hematopoietic cells in a cell free DNA sample. In some embodiments, the cancer variants can be distinguished from a somatic variants originating from hematopoietic cells based on fragment size distribution.
Patent WO-2021055668-A1 (WO)
Title: Inhibiting ubiquitin specific peptidase 9x
Inventor: LYNES MAUREEN
IPC: A61K39/12
Filed: 2020-09-18
Abstract: This disclosure provides methods of treating cancer with an inhibitor of ubiquitin specific peptidase 9X alone or in combination with an immune checkpoint pathway inhibitor.
Patent WO-2021072104-A1 (WO)
Title: Mixing device and methods of operation
Inventor: FRANKS WILLIAM
IPC: B29B7/76
Filed: 2020-10-08
Abstract: Apparatus for mixing polymer, the apparatus comprising (i) a mixer housing including an internal chamber, said internal chamber having first and second sections in fluid communication with each other through a passageway; (ii) a first ram received in said first section; and (iii) a second ram received in said second section, where the apparatus is adapted to receive a composition including polymer within said internal chamber and move said composition between said first and second chambers through said passageway by operation of said first and second rams.
Patent WO-2021108046-A1 (WO)
Title: Réseau de del ayant un substrat transparent doté d'une couche conductrice pour une propagation de courant améliorée
Inventor: HURNI CHRISTOPHE ANTOINE
IPC: H01L33/42
Filed: 2020-10-21
Abstract: Dans un ensemble DEL à puce retournée ayant un réseau de DEL formées sur le même substrat, différentes DEL du réseau ont des distances différentes par rapport aux contacts n de l'ensemble. Ceci peut provoquer une concentration de courant au fur et à mesure que le courant doit se propager depuis les contacts n à travers le substrat vers chacune des DEL les plus éloignées du réseau de DEL, nécessitant des DEL qui sont plus éloignées pour être excitées avec une tension plus élevée afin de recevoir une quantité souhaitée de courant. Afin de propager le courant plus uniformément à travers l'ensemble DEL et réduire une différence de tension entre les DEL les plus proches et les plus éloignées du réseau, une couche de propagation de courant ayant un matériau conducteur (par exemple, un oxyde conducteur) est formée sur une surface du substrat de l'ensemble DEL. La couche de propagation de courant peut être une couche de substrat ou être conçue pour augmenter l'extraction de lumière à partir des DEL du réseau.
Patent WO-2021087007-A1 (WO)
Inventor: BERGLUND JOHN
IPC: C07K14/47
Filed: 2020-10-28
Abstract: Provided herein, in some embodiments, are nucleic acid constructs encoding RNA molecules comprising one or more introns that can be regulated (e.g., autoregulated), and that are useful for delivery in a recombinant viral vector. Aspects of the application provide compositions and methods for delivering regulated (e.g., auto-regulated) gene expression constructs to a subject.
Patent WO-2021097086-A1 (WO)
Title: Plant vectors, compositions and uses relating thereto
Inventor: SIMON ANNE
IPC: C12N9/12
Filed: 2020-11-12
Abstract: The present disclosure relates to a single stranded RNA vector suitable for introducing a therapeutic agent, such as a peptide, a protein or a small RNA, into a host plant. The vector does not encode for any movement protein or coat protein, but is capable of systemic and phloem-limited movement and replication within the host plant.
Patent WO-2021097343-A1 (WO)
Title: Diagnostic test kits for sample preparation and analysis
Inventor: WANG YUNYUAN VIVIAN
IPC: G01N33/493
Filed: 2020-11-13
Abstract: A method for analyzing a sample includes introducing the sample into a vessel including a cation-exchange resin, where the cation-exchange resin has a high affinity to one or more interferent species in the sample, directing the sample through the cation-exchange resin to thereby capture one or more interference species in the cation-exchange resin to purify the sample, and releasing the purified sample from the vessel. Additionally, a method for analyzing a sample includes receiving an image depicting a diagnostic test region and a color reference chart, converting a test region image portion of the image to an analytical color space, determining first and second coordinate values characterizing the test region image portion in the analytical color space, and providing a quantitative measurement of an analyte of interest in the sample based on the first and/or second coordinate values and a predictive formula based on the color reference chart.
Patent WO-2021097416-A1 (WO)
Inventor: BURGGRAAFF MAARTEN CORNELIS
IPC: B08B9/027
Filed: 2020-11-16
Abstract: L'invention concerne un ensemble de décokage modulaire avec un conteneur transportable et de multiples modules préfabriqués qui peuvent être installés à l'intérieur du conteneur transportable, et des procédés de formation d'une unité de décokage avec une pluralité de modules préfabriqués à l'intérieur d'un conteneur.
Patent WO-2021127206-A1 (WO)
Title: Wedge-shaped multi-layer interlayer with outer skin layers of varying thickness
Inventor: CHEN WENJIE
IPC: B32B27/30
Filed: 2020-12-17
Abstract: Multiple layer interlayers having enhanced optical and acoustic properties are provided, along with methods of making and using the same. Interlayers as described herein may include at least two outer skin layers and an inner core layer, with one of the outer skin layers having a different thickness than the other at one or more locations along the interlayer. The multi-layer interlayer may also exhibit acoustic properties and, in some cases, may have an overall wedged thickness profile. Additionally, in some aspects, interlayers and laminates formed therefrom may also provide reduced infrared energy transmission, without sacrificing acoustic and/or optical performance.
Patent WO-2021127556-A1 (WO)
Title: Methods for treating cancer comprising low dose radiation
Inventor: WELSH JAMES W
IPC: A61K45/06
Filed: 2020-12-18
Abstract: The present disclosure provides methods of treating cancer in a patient comprising administering a combination of a low dose radiotherapy and an immune checkpoint inhibitor therapy. The patient may be further administered a cell therapy, such as chimeric antigen receptor T-cell therapy or chimeric antigen receptor NK-cell therapy. The low dose radiation modulates the tumor microenvironment of solid tumors to allow better efficacy, activation, and infiltration of the anti-tumor effector immune cells.
Patent WO-2021022286-A1 (WO)
Inventor: KONYA ABIGAIL MARY
IPC: A01P1/00
Filed: 2020-07-17
Abstract: An antimicrobial cleaning composition having a pH of from about 9 to about 14 wherein the composition comprises a bispyridinium alkane antimicrobial active and the composition is substantially free of a quaternary ammonium antimicrobial active.
Patent WO-2021154691-A1 (WO)
Title: Beam failure recovery assistance in upper band millimeter wave wireless communications
Inventor: RAGHAVAN VASANTHAN
IPC: H04B7/08
Filed: 2021-01-26
Abstract: Methods, systems, and devices for wireless communications are described in which a first wireless device and second wireless device may establish communications using a first beam and a second beam. The first wireless device may perform separate radio link monitoring (RLM) procedures to monitor beam quality for each of a transmit beam and receive beam that are used for communications with a second wireless device. The separate RLM procedures may be used at the first wireless device to determine that one of the transmit or receive beams is experiencing a quality degradation or a radio link failure (RLF), and an RLF indication may be provided to the second wireless device.
Patent WO-2021211191-A1 (WO)
Title: Novel lymphoid-specific tyrosine phosphatase (lyp) inhibitors
Inventor: ZHANG ZHONG-YIN
IPC: A61K47/26
Filed: 2021-02-05
Abstract: The present disclosure relates to novel lymphoid-specific tyrosine phosphatase (LYP, encoded by the PTPN22 gene) inhibitors, and to methods of making and using the novel LYP inhibitors. Thus, the compounds according to the disclosure may be used for treating diseases or disorders associated with PTPN22 genetic polymorphism, including type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosis, Graves' disease, Addison's disease, vitiligo, juvenile arthritis, Hashimoto thyroiditis, and other rarer diseases. Furthermore, these LYP inhibitors may be served for a novel class of cancer immunotherapy. The compounds can be injected or orally administered.
Patent WO-2021178112-A1 (WO)
Inventor: GNANASAMBANDAM NATHAN
IPC: H04W12/02
Filed: 2021-02-09
Abstract: A node that is part of a network of nodes with access to a distributed ledger may receive a transaction request to perform one or more operations associated with the distributed ledger, wherein the one or more operations include causing a record of a transaction to be stored using the distributed ledger. The node may determine, based on credential information associated with the transaction request, whether to allow the one or more operations to be performed. The node may perform the one or more operations based on determining to allow the one or more operations to be performed. The one or more operations may include adding the record of the transaction to the distributed ledger. At least a subset of the content may be included in the record. The node may cause one or more other nodes, of the network of nodes, to have access to the distributed ledger.
Patent WO-2021178589-A1 (WO)
Inventor: KRUGER CHRISTOPHER RICHARD
IPC: G09B19/00
Filed: 2021-03-03
Abstract: Systems and methods include an exercise device receiving a sequence of camera images of a user performing an exercise, identifying a plurality of anatomical points of the user based at least in part on the sequence of camera images, determining a user performance level based, at least in part, on an analysis of the plurality of anatomical points; and providing corrective feedback to the user when the user performance level fails to satisfy performance criteria for the exercise. A workout device includes a display device for displaying exercise content and a housing with a recessed portion and a camera arm configured to be inserted in the recessed portion of the housing in a first position and partially inserted in the recessed portion of the housing in a second position.
Patent WO-2021202676-A1 (WO)
Title: Methods for signaling residual coding method of transform skip blocks
Inventor: YE YAN
IPC: H04N19/122
Filed: 2021-03-31
Abstract: The present disclosure provides methods of signaling residual coding method for transform skip blocks. An exemplary method includes: determining, based on a first flag, whether to signal a slice residual coding flag in a slice header, wherein the slice residual coding flag indicates whether transform-skip residual coding is enabled for one or more transform-skip (TS) or block-DPCM (BDPCM) coded blocks in a slice associated with the slice header; and processing the slice based on the determination.
Patent WO-2021225739-A1 (WO)
Title: Signaling aspects of a conditional primary secondary cell change procedure in multi-radio access technology dual connectivity
Inventor: PURKAYASTHA PUNYASLOK
IPC: H04W36/36
Filed: 2021-04-08
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a master node (MN) may receive a message indicating that a user equipment (UE) has determined that a condition for a conditional primary secondary cell (PSCell) change has been satisfied for a candidate target PSCell. The candidate target PSCell may be one of a set of candidate target PSCells associated with the UE in a conditional PSCell change configuration provided by a base station. The MN may transmit, to a source secondary node, a confirmation message associated with the conditional PSCell change. Numerous other aspects are provided.
Patent WO-2021216488-A1 (WO)
Title: Variants de l'il-2 présentant une liaison réduite au récepteur alpha de l'il-2 et ses utilisations
Inventor: WU JIAXI
IPC: A61K38/20
Filed: 2021-04-20
Abstract: La présente divulgation concerne des variants de l'IL-2 et des procédés pour leur utilisation, y compris des procédés de traitement ou d'inhibition d'un cancer ou d'une tumeur. Les variants de l'IL-2 peuvent avoir une capacité réduite à se lier ou à activer l'IL-2Ra. Les variants de l'IL-2 peuvent conserver la capacité de se lier ou d'activer l'IL-2RP et/ou le Πν-2Κβγ. En outre, les variants de l'IL-2 présentent une activité Treg réduite, mais conservent la capacité d'activer les cellules NK et les cellules effectrices T.
Patent WO-2021262299-A1 (WO)
Inventor: LUO JIANGHONG
IPC: H04W74/08
Filed: 2021-04-21
Abstract: This disclosure provides systems, methods, and apparatus, including computer programs encoded on computer storage media, for performing a common channel sensing procedure for transmissions via a mobile termination (MT) role or via a distributed unit (DU) role of an integrated access and backhaul (IAB) node, or both. In one aspect, the IAB node may obtain channel access for transmissions via the MT role or the DU role, or both, using the same channel sensing procedure. The IAB node may select a timing of a sensing slot for the common channel sensing procedure in accordance with a capability of the IAB node and a timing of the transmissions. The IAB node may initiate a channel occupancy time (COT) for the transmissions via the MT role or the DU role, or both, as a result of determining that a measured energy detection (ED) value satisfies an ED threshold.
Patent WO-2021217067-A1 (WO)
Inventor: BROWN AMEER
IPC: H04H60/06
Filed: 2021-04-23
Abstract: A system and methods for facilitating transactions relating to slots in a content promoter's performance. The system allows content promoters to publish available slots in their performances and receive submissions from artists requesting their content be presented in those slots. The system facilitates transactions between promoters and artists using an escrow and "proof of play" system. The escrow system charges an artist in advance for content submitted to be presented, but holds payment of those charges until after the promoter has presented the content and proof of play has been confirmed. Proof of play may be directly confirmed by the artist, may be confirmed by the system, or may be provided to the artist in an audiovisual recording made by the promoter. The escrow and proof of play system helps protect promoters and artists against potential default by either party to the transaction.
Patent WO-2021222312-A1 (WO)
Inventor: ROSS KEVIN
IPC: H04B1/00
Filed: 2021-04-27
Abstract: An example mounting apparatus for a wireless communication node may comprise: a first weighting-element enclosure having a first set of connectors that extend from the first weighting-element enclosure; a second weighting-element enclosure having a second set of connectors that extend from the second weighting-element enclosure, and wherein the first weighting-element enclosure is connected to the second weighting-element enclosure via two joints that are disposed between the first set of connectors and the second set of connectors; a post that is affixed to either the first weighting-element enclosure or the second weighting-element enclosure; one or more communication-equipment enclosures that are each attached to the post and are each adapted to house respective equipment for the wireless communication node; and at least a first support strut that is connected between the post and a first one of the two joints disposed between the first weighting-element enclosure and the second weighting-element enclosure.
Patent WO-2021222696-A1 (WO)
Inventor: CURTISS ROY
IPC: A61K39/112
Filed: 2021-04-30
Abstract: Disclosed herein are unique adjuvant compositions comprising an attenuated derivative of a self- destructing bacterial pathogen that undergoes lysis  in vivo . In exemplary embodiments, the bacterial pathogen is a  Salmonella  spp. Also disclosed are methods for enhancing an immune response using the adjuvants disclosed herein.
Patent WO-2021222887-A1 (WO)
Inventor: ZHONG YING
IPC: B41F16/00
Filed: 2021-05-03
Abstract: The invention relates to a non-contact printing method and system as well as to a printed sensor. The method includes the steps of disposing a substrate (130) between a discharge electrode (110) and a printing material (140) such that the substrate (130) is spaced apart from the printing material (140); and activating the discharge electrode (110) to generate an electric field between the substrate (130) and the printing material (140), wherein the printing material (140) moves onto a surface (132) of the substrate (130) when the electric field attracts the printing material (140) to the surface (132) of the substrate (130). A corresponding printing system and printed sensor are also provided.
Patent WO-2021236412-A1 (WO)
Title: Frac plug system with integrated setting tool
Inventor: HERN GREGORY
IPC: E21B33/129
Filed: 2021-05-13
Abstract: A frac plug system, downhole tool and method of securing a frac plug system in a wellbore in a formation. A mandrel includes a first end and a second end. A setting assembly is coupled to the mandrel at the first end, and an anchor is arranged at the second end of the mandrel and receptive to the setting assembly. The anchor is settable to engage the wellbore. A bottom sub is arranged at the second end of the mandrel and includes a first member movable relative to the mandrel. A gas generates a pressure to shift the first member along the mandrel to move the anchor against the setting assembly, securing the setting assembly in the wellbore via radial deployment of the anchor. The mandrel is separated from the bottom sub to leave the setting assembly and the anchor in the wellbore.
Patent WO-2021252894-A1 (WO)
Title: Lidar beam walk-off correction
Inventor: MICHAELS ANDREW
IPC: G01S17/42
Filed: 2021-06-11
Abstract: A light detection and ranging (LIDAR) device includes a pixel, a mirror, and a birefringent material. The pixel is configured to emit light having a first polarization orientation. The mirror is configured to reflect the light to a surface. The birefringent material is disposed between the pixel and the mirror. The birefringent material introduces an offset in a position of the emitted light having the first polarization orientation propagating through the birefringent material. The birefringent material shifts a reflected beam in space horizontally back on the pixel.
Patent WO-2021257819-A1 (WO)
Title: Microfluidic systems and methods for sorting particles
Inventor: CHO SUNG HWAN
IPC: B01D43/00
Filed: 2021-06-17
Abstract: Provided herein are devices, systems, and methods for particle sorting, including cell sorting, using microfluidics cartridges and microchips and the manufacture of the microfluidics cartridges and microchips by high-throughput approaches. Such methods, devices, and systems can be used to identify, sort, and collect a subset of particles or a single particle from a sample. The capability to manufacture such microfluidic tools in high volume may lower production costs and allow for the microfluidic tools to be used as consumables.
Patent WO-2021262835-A1 (WO)
Inventor: HARVEY ROSS
IPC: H05B45/48
Filed: 2021-06-23
Abstract: The present disclosure includes methods and systems for creating, using, and controlling LED headlight topologies and matrices that require fewer parts, electricity, and power, while allowing for advanced features such as bend lighting. The disclosed methods and systems can enable the use of smaller electrical systems, including control systems for LED and other headlight topologies. The disclosed methods and systems can also take advantage of pixel pairing and time multiplexing, among other methods, to manage electrical flow to minimize power needed over the circuit at given times, thus reducing the amount of material needed to create the LED headlight topology and related methods and systems for creating, using, and controlling the LED headlight topology.
Patent WO-2022006259-A1 (WO)
Title: Immunostimulatory compositions and methods
Inventor: TIDMARSH GEORGE
IPC: A61K39/145
Filed: 2021-06-30
Abstract: Provided herein are methods of enhancing an immune response to a vaccine in a subject comprising concurrently administering the vaccine and an immunostimulatory composition comprising PHAD to the subject.
Patent WO-2022011178-A1 (WO)
Title: System and method for generating content recommendation rules for a vehicle
Inventor: JORDAN CHRISTOPHER PHILIP
IPC: G06F9/451
Filed: 2021-07-08
Abstract: Embodiments are directed towards a system and method of generating content recommendation rules for a vehicle head unit. A content recommendation and telemetry information of a vehicle are received by at least one remote server. The at least one remote server determines at least one content recommendation rule based on the at least one content recommendation and the telemetry information. The at least one remote server provides the at least one content recommendation rule to the head unit. The head unit detects an event associated with the head unit and selects content to present to the user based on a comparison of the detected event to the at least one content recommendation rule. The head unit then presents the selected content to the user.