baber/WOPTO huggingface dataset:
Patent CR-20200605-A (CR)
Title: Compounds and methods for reducing fxi expression
Inventor: BUI HUYNH-HOA
IPC: C12N15/113
Filed: 2019-05-08
Abstract: <p>Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of FXI RNA in a cell or subject, and in certain instances reducing the amount of FXI protein in a cell or subject. Such compounds, methods, and pharmaceutical compositions are useful to prevent, treat, or ameliorate at least one symptom of a thromboembolic condition without a significant increase in a bleeding risk. Such thromboembolic conditions include deep vein thrombosis, venous or arterial thrombosis, pulmonary embolism, myocardial infarction, stroke, thrombosis associated with chronic kidney disease or end-stage renal disease (ESRD), including thrombosis associated with dialysis, or other procoagulant condition. Such symptoms include decreased blood flow through an affected vessel, death of tissue, and death.</p>
Patent CR-20220305-A (CR)
Title: Methods of treating pulmonary arterial hypertension
Inventor: MARESTA ALESSANDRO
IPC: A61K31/505
Filed: 2020-11-27
Abstract: The disclosure relates to methods of reducing the risk of disease progression in a patient with pulmonary arterial hypertension (PAH), comprising administering to a patient in need thereof, an initial triple combination therapy of an endothelin receptor antagonist (ERA), a phosphodiesterase type 5 (PDE-5) inhibitor, and a prostacyclin receptor agonist (IP receptor agonist).
Patent EC-SP045087-A (EC)
Title: Nueva formulación de jarabe de epinastina seco y acuoso
IPC: A61P25/04
Filed: 2004-04-26
Abstract: La presente invención se refiere a una nueva formulación de epinastina en forma de polvo (jarabe seco) para ser mezclada con agua antes de usarse. La epinastina puede usarse como base libre o bien como sal de la misma aceptable farmacéuticamente. La epinastina, entre otras cosas, se aplica al tratamiento de alergias, dolor, en particular el dolor crónico y el dolor producido por una inflamación, la migraña, el asma, la rinitis, la conjuntivitis y/o la bronquitis. En particular, la formulación es para el tratamiento de alergias, dermatitis, rinitis, conjuntivitis, bronquitis y asma.
Patent EC-SP077371-A (EC)
Title: Composiciones fungicidas sinergicas
Inventor: EHRENFREUND JOSEF
IPC: A01N45/02
Filed: 2007-04-04
Abstract: La presente invención se refiere a nuevas composiciones fungicidas para controlar enfermedades fitopatógenas en plantas útiles o sobre un material de propagación de las mismas, que comprende aplicar a las plantas útiles, al lugar de las mismas o al material de propagación de las mismas, una combinación de los componentes A) y B) en una cantidad sinérgicamente eficaz donde el componente A) es un compuesto de fórmula I donde R1 es difluormetilo o trifluormetilo; Y es -CHR2- o y R2 es hidrógeno o alquilo C1-C6; o un tautómero de dicho compuesto; y el componente B) es un compuesto seleccionado entre los compuestos conocidos por su actividad fungicida y/o insecticida que es particularmente eficaz para controlar o prevenir enfermedades fungales de plantas útiles.
Patent EC-SP099609-A (EC)
Title: Obtención, aislamiento y crioconservación de células endometriales/ menstruales
Inventor: WALTON MERCEDES A
IPC: C12N5/00
Filed: 2009-09-01
Abstract: La invención provee composiciones que comprenden células madre menstruales (MSCs (por sus siglas en inglés), y métodos, procesos y sistema que las involucra. Las MSCs (por sus siglas en inglés) son procesadas a partir del flujo menstrual recogido durante la menstruación. Las MSCs (por sus siglas en inglés) pueden crioconservarse, procesarse mediante varios cultivos y pasos de selección para uso terapéutico o cosmético. Las MSCs (por sus siglas en inglés) crioconservadas pueden descongelarse para la preparación de productos para uso terapéutico o cosmético. Las MSCs (por sus siglas en inglés) expresan CD9, CD10, CD13, CD29, CD44, CD49e, CD49f, CD59, CD81, CD105, CD166, y HLA clase I, y tienen una baja o nula expresión de CD3 y HLA clase II.
Patent EC-SP972124-A (EC)
Title: Composiciones farmaceuticas a base de diclofenaco
Inventor: REINER GIORGIO
IPC: C07C39/30
Filed: 1997-05-19
Abstract: Se describen nuevas composiciones farmacéuticas para uso oral que contienen diclofenac junto con carbonatos y bicarbonatos de metales alcalinos y sustancias sazonantes particulares. Estas composiciones son totalmente degustables y están libres de cualquier sabor desagradable u otros efectos secundarios.
Patent FI-20020453-A (FI)
Inventor: LAHTINEN ESA
IPC: G05B9/03
Filed: 2002-03-11
Abstract: The invention relates to a method and an apparatus for arranging redundancy in a process control system comprising at least one client device, at least one data source and at least one server device providing data transfer between the client device and the data source. The method comprises arranging, for the client device, at least two parallel logical connections for transferring substantially the same data between at least one data source and the client device. At the client device, property information on data units transferred via different logical connections is checked, the client device being provided with predetermined order criteria for the property information. At the client device, property information on parallel data units transferred via different logical connections is compared. Data units delivered via the logical connection having, according to the predetermined order criteria, the best property information are selected for the use of one or more applications processing the data units.
Patent FI-20206267-A (FI)
Title: Method and computer program product for selecting supply air devices
Inventor: HUUSKONEN ESA
IPC: G06Q50/08
Filed: 2020-12-08
Abstract: The method for selecting supply air device to a ventilation system of a space from a group of supply air devices comprises steps of defining total air flow rate of the space, defining acceptable noise level of the space, selecting a first subgroup of possible supply air devices based on the air flow capacities of the supply air devices and acceptable noise level, determining the number of supply air devices needed in the space and calculating design air flow for the supply air device. The method further comprises steps of defining at least one additional rating property for the supply air devices, evaluating the performance of each supply air device according to each additional rating property and scoring the performance, calculating combined rating value for each supply air device, ranking the supply air devices based on the combined rating value and selecting supply air device based on said ranking.
Patent FR-1564445-A (FR)
IPC: E05D15/48
Filed: 1968-05-24
Granted: 1969-04-18
Abstract: 1,182,394. Window hinge. WONDER DOOR HOLDINGS (PROPRIETARY) Ltd. 16 May, 1968 [26 May, 1967; 30 Aug., 1967; 20 Nov., 1967; 12 Jan., 1968; 15 Feb., 1968], No. 23324/68. Heading E2F. A hinge includes a formation 68 on a bearing leaf 62 releasably engageable with a complemental formation 70 in a closure e.g. a door or window 72, and a pintle 54 which is right-angled, the bearing leaf 62 being at right angles to the fixed leaf 50. A door or window assembly includes such hinges along at least two sides, to enable opening about at least two sides thereof. In one form (see Fig. 2), a pin 74 passes through the complemental formation 70 to engage in an orifice 76 in the element 68, thereby locking the arrangement. Cables, or similar means, are attached to the tails of the pins and associated with the handle, actuation of which in a certain direction causes retraction of the pins. If it is not desired to lock the hinges, as described above, the pins may be replaced by spring-loaded balls so that the closure is opened merely by pushing at the desired side. The invention provides for two-way, threeway or four-way opening of doors and windows. For three-way opening, two of the right-angled pintle hinges are located in adjacent corners and other disengageable hinges are located on the two sides adjacent to the two right-angled pintle hinges. For four-way opening, a right-angled pintle hinge is located at each corner.
Patent GB-1013744-A (GB)
IPC: D03D49/20
Abstract: 1,013,744. Take-up motions. HAYWORTH & SIMPSON Ltd. Sep. 2, 1964 [Sept. 2, 1963], No. 34573/63. Heading D1E. A cloth beam rests in the bight of two rollers which are driven by an independant motor 1 by way of a clutch pawl and satchet mechanism 4, 5 and gear wheels 15, 13.
Patent GB-1047282-A (GB)
IPC: A43D87/00
Abstract: 1,047,282. Boots &c. UNITED DYNAMICS CORPORATION. Jan. 20, 1965, No. 2489/65. Heading A3B. The heel seat 14 and lift 12 of a shoe having a detachable top lift is shaped by a trimming cutter and abrasive belt to the shape of a template 26 which has the same shape as the top lift and which is detachably secured to the lift 12 in the position normally occupied by the top lift but spaced heightwise from lift as shown in Fig. 6. As described the template 26 and the top lift are connected to the lift 12 by snap fasteners 20, 30. The heel is first trimmed by a cutter 36 which has a freely rotating rand guide 50 and a freely rotating guide 44. The shoe is supported on a table 32 and is moved by hand against the cutter 36 until the guide 44 engages the template 26. The guide 44 is slightly larger in diameter than the cutter 36 so that an over-size heel is produced. The cutter assembly is mounted on a sleeve 38 which is slidable heightwise against the bias of a spring 56 on the drive shaft 34 so that rand guide 50 can follow the heightwise contour of the rand. The cutter assembly can be raised by a wedge 66 operated by a treadle (not shown) initially to position the rand guide in the crease. The cutter assembly is then replaced by a drum 86, Fig. 7 (not shown) having a guide. 98 (corresponding to the guide 44) and around which passes an abrasive belt 84. The belt 84 reduces the heel to its correct size and imparts a smooth finish to the heel. In a modification (not shown) the cutting assembly and the scouring assembly are each mounted on separate shafts and can be moved heightwise independently by treadles.
Patent GB-1053366-A (GB)
IPC: F15B13/00
Abstract: 1,053,366. Valves. DAMIC CONTROLS Ltd. Oct. 28, 1964 [Oct. 30, 1963], No. 42878/63. Heading F2V. Four inlet ports e.g. for supplying oxygen, helium &c., in deep sea diving, may each be connected in turn via frusto-conical seatings 6 uniformly radially disposed around a common centre to an outlet 3 upon selectively unseating frusto-conical closures 7 against springs 15 by engagement of projecting spigots 16 thereof with one of four radial arms 19 carried by a handoperated lever 17 pivotable about a ball and socket 20 21. The lever 17 is guided by a gate to prevent opening two valve closure members simultaneously and is locked in open position by ball catches or alternatively the arm 19 may be guided between pins 22 (Fig. 1, not shown). The closures 7 are pressure balanced by waisted portions 9, 10 connecting the frusto conical seatings 6 to pistons 12, 11 sealingly engaged within bores 13, 4 by 0 type sealing rings. An O type sealing ring 8 is retained within a recess in the cylindrical part of the closure 7 and projects at the junction with the frusto conical portion so that it is urged more firmly into contact with the seating 6 by pressure of gas. The closure may also be constructed in accordance with Specifications 840,559, 875,431 or 988,894.
Patent GB-1084258-A (GB)
IPC: B41F27/10
Abstract: 1,084,258. Printing-surfaces. TOKYOKIKAI-SEISAKUSHO KABUSHIKIKAISHA. Oct. 20, 1964, No. 42742/64. Heading B6C. Apparatus for clamping a lead plate on a printing cylinder 12 comprises a plurality of hook members 49-56, Fig. 1, fixed to the surface of the cylinder, a rotatable shaft 18 mounted parallel to the cylinder axis in a recess 16, a plurality of eccentrics 20-22 &c., Fig. 2, provided at spaced intervals along the shaft, a ring member 76 loosely surrounding each eccentric, said members being shaped adjacent their upper surfaces to provide pawls 23-30 pivotable from a release position within the cylinder, Fig. 5A (not shown), to a plate clamping position, Fig. 5, and adjacent their lower surfaces to provide projections 77 which are engaged by springs 82 to bias the pawls into the Fig. 5 position, a gear-wheel 44 mounted on the end of the shaft 18, an arcuate member 59 which is geared internally to mesh with the wheel 44, and an operating lever, Fig. 9 (not shown), arranged to rotate the member 59 circumferentially so as to rotate the shaft 18 and move the pawls 23-30 between the release and clamping positions. The plates extend through 180 degrees and two sets of clamping devices are provided on each cylinder. The pawls may alternatively be pressed into the clamping position by leaf springs, Fig. 11 (not shown). The pawls are separated by packing members 31-35, Fig. 2, and, in addition, a plurality of plate release pawls 87-90, Fig. 1, are mounted on the shaft 18. Looking devices are provided so that the operating lever cannot be retracted except when the plate is clamped or released, Fig. 9 (not shown). A projecting pin indicates when the plate is clamped in position. The gear-wheel 44 is adjustably mounted on splines 19 on the shaft by means of a lock nut 46 and a bushing 43 mounted on threads 19<SP>11</SP>, 191 respectively, said threads being different from each other.
Patent GB-1226105-A (GB)
IPC: H01Q1/52
Filed: 1967-06-08
Abstract: 1,226,105. Aerials; radio receiving apparatus. BRITISH BROADCASTING CORP. 7 June, 1968 [8 June, 1967], No. 26547/67. Headings H3Q and H4A. A directional radio receiving system comprises a multi-element aerial array in which each element is substantially alike and is coupled through an amplifier or other active device to common output terminals. The input impedance of each amplifier is arranged to be not less than twice the impedance of the associated aerial element, and it is stated that the effect of mutual impedances between the elements can thereby be made negligibly small, so reducing side-lobes and allowing operation over a wide band of frequencies. As described, each element of an eightelement array is in the form of a metal tube folded dipole having upper and lower limbs 10, 15, the former having within it an R.F. cable 11 connecting a socket 13, which is mounted on a metal block 14 welded to the dipole, to the output of a solid state amplifier 12. The said amplifier is wired to a printed circuit on a glass-fibre board and is housed within a metal tube 24. It has an input terminal 23 which is connected by means of a grub-screw 22 to one limb of the folded dipole, the other limb making connection with the tube 24. An insulating spacer 18 separates the limbs of the dipole, around which an insulating tube 19 is clamped by clips 20, 21. The output impedance of the amplifier 12 is arranged to match the impedance of the cable 11. Adjustable short-circuits 25 across the limbs of the dipole are provided for tuning out the total capacitance across the drive point at the centre frequency of operation.
Patent GB-1226253-A (GB)
IPC: G01N25/62
Filed: 1969-02-20
Abstract: 1,226,253. 6 - Phenyl - 2,3,5,6 - tetrahydroimidazo[2,1 - b]thiazole. RHONE-POULENC S.A. 20 Feb., 1969 [21 Feb., 1968], No. 9367/69. Heading C2C. Optical resolution of the title compound is effected by fractional solubilization or crystallization of its z- or d-dibenzoyltartrates from water or from a C 1-3  aliphatic alcohol diluted by at least 10 vol. per cent of water.
Patent GB-1227601-A (GB)
IPC: C07C29/14
Filed: 1967-07-03
Abstract: 1,227,601. Production of alcohols. IMPERIAL CHEMICAL INDUSTRIES Ltd. 12 June, 1968 [3 July, 1967], No. 30578/67. Heading C2C. Alcohols, preferably C 1-12  saturated aliphatic or aryl and alkaryl alcohols, are produced by reduction of the corresponding aldehyde with formic acid, preferably present in 10-500% excess in a liquid medium containing in solution a complex of Ir, Pt, Ru or Os. The preferred complexes have the formula IrH x A 3-x Z m L n  in which A is an anion, Z is a tertiary phosphine or arsine group, L is a CO group or a nitrogen containing organic base, x is 0 or 1-3 and m and n are integers such that m + n = 2 or 3, m is at least 1 and n may be 0, e.g. IrH 3 (PR 3 )p wherein p is 2 or 3 and R is alkyl or aryl, perferably phenyl or alkylphenyl. The reaction may be carried out in the presence of free tertiary phosphine, temperatures may be from 50- 120‹ C. and the pressure may be 1 atmosphere. A solvent may be used, e.g. a C 1-5  saturated aliphatic carboxylic acid in which case the product alcohol is normally at least partially esterified. The catalyst may be present in 0À05-0À5% by weight expressed as metal based on the weight of the liquid medium and aldehydes may be selectively reduced in the presence of a ketone or of a nitro- or nitrile group. The examples describe the conversion of butyraldehyde to butanol and butyl acetate, isobutyraldehyde to butanol, crotonaldehyde to butanol and butyl acetate, p-nitrobenzaldehyde to p-nitrobenzyl alcohol and p-nitrobenzylacetate and benzaldehyde to benzyl alcohol. Butyraldehyde is produced as a biproduct in the conversion of crotonaldehyde to butanol and butylacetate .
Patent GB-1230531-A (GB)
IPC: A23L29/281
Filed: 1969-05-05
Abstract: 1,230,531. Cold-water soluble gelatin compositions. CRODA (B.G.C.) Ltd. 29 July, 1969 [5 May, 1969], No. 22852/69. Heading A2B. A cold-water soluble gelatin composition e.g. for use in desserts, is prepared by spray drying an aqueous solution comprising only gelatin and glucose and having a glucose concentration (on a dry weight basis) of 1 to 4 times that of gelatin. The solution may be prepared from an acidtype gelatin prepared from an acid extract of skin or demineralised bone or a limetype gelatin and glucose syrup. The gelatin composition may be used with icing sugar, non-fat milk solids, flavours and colourings.
Patent GB-1231130-A (GB)
IPC: C08L27/06
Filed: 1969-12-05
Abstract: 1,231,130. P.V.C. compositions. SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ N.V. 5 Dec., 1969, No. 59509/69. Heading C3P. Powdered P.V.C. is mixed with pellets of ethylene/vinyl ester copolymer in a high speed mixer at a temperature above 130‹ C. at which the P.V.C. remains powdery. Preferably other constituents are mixed with the P.V.C. before the copolymer is added. In the examples such materials are tribasic lead sulphate, dibasic lead stearate, calcium stearate and glycerol monostearate. The copolymer added is ethylene/  vinyl acetate.
Patent GB-1233330-A (GB)
IPC: D06P3/54
Filed: 1969-12-18
Abstract: 1,233,330. Conditioning polyester material.: FARBWERKE HOECHST A.G. 18 Dec., 1969 [18 Dec., 1968], No. 61737/69. Heading D1P. Polyester fibrous material is treated to remove oligomers formed during manufacture and hence enhance its processing properties with an aqueous solution or emulsion of a polyglycol ether compound having the general formula: wherein n is either 1 or 2, R#OH, or an organic radical with not greater than C 30 , and if n is 1 Y is greater than or equal to 20 and X+Z greater than or equal to 15, if n is 2 Y is greater than or equal to 10 and X+Z greater than or equal to 7; and X or Z may be 0, the M.W. of the compound being not greater than 7,000. The polyglycol ether compoundis preferably a reaction product of ethylene oxide and propylene oxide with a saturated or unsaturated straight-chain or branched monohydric aliphatic alcohol, an alkane diol, a primary or secondary alkyiamine, a saturated or unsaturated aliphatic carboxylic acid or amide, a phenol, or a mono, or dialkylphenol. Treatment of the polyester which may last for 10 minutes to 1 hour with the aqueous solution which may contain 0.5 to 4 g/l of polyglycol ether is preferably carried out at a temperature of 50-125‹C.
Patent GB-1234051-A (GB)
IPC: B01D53/86
Filed: 1968-06-25
Abstract: 1,234,051. Absorbent oxidation catalysts. E. I. DU PONT DE NEMOURS & CO. 25 June, 1968 [1 Aug., 1967; 6 Dec., 1967], No. 30224/ 68. Heading B1E. Catalytic absorbent shaped structures are made by preparing a homogeneous aqueous mixture of a gel-forming material and a metal salt decomposable to a catalytic metal or catalytic metal oxide, allowing the mixture to set to a gel containing the decomposable salt and calcining the gel to decompose the salt to the catalytic metal or metal oxide and form a shaped structure comprising a network of pores. The gel forming material may be colloidal SiO 2 , dehydrated gypsum or a hydroxide of Al, Zn, Ba, Ca, Cr, Mg, La, Mo, W, Ce, Sr, Fe, Ti, Zr, Hf or a rare-earth metal. The decomposable metal salt is a chromite, chloride, nitrate, ammine, basic chromate, manganate, oxalate, acetate, carbonate, formate, benzoate, succinate, chelate, or acetyl acetonate of Ru, Pd, Pt, Rh, Co, Mi, Ce, Fe, Mn, Cr, Cu, Zn, Cd, Bi, Ag, Mo, V, W, Su or a rare-earth. Catalysts are described which contain Mn, Ni, Co, Cr supported on C, Al 2 O, and SiO, which are immersed in Pd and Pt solutions before drying and calcining.
Patent GB-1238831-A (GB)
IPC: G02F1/00
Filed: 1969-01-08
Abstract: 1,238,831. Spinels. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. 8 Jan., 1969 [11 Jan., 1968], No. 1118/69. Heading C1A. [Also in Division H4] Crystals of composition ACr 2 Z 4 , where A is Cd, Zn, Hg, Mn, Fe<SP>II</SP>, Co, Mg, Ni, Pb, ¢(Cu<SP>I</SP>+ Ga), ¢(Cu<SP>I</SP>+In), ¢(Cu<SP>I</SP>+Fe<SP>III</SP>), ¢(Ag+In) and/or ¢(Ag+Fe<SP>III</SP>) and Z is S, Se and/or Te which exhibit the Faraday effect and have a spinel structure, a magnetic permeability (defined) greater than 1.2 and a resistivity at the Curie point greater than 100 ohm cm., may be used for infra-red radiation at 1-20 Á. CdCr 2 Se 4  is made by dissolving CdSe and Cr 2 Se 3  in molten CdCl 2  and cooling slowly.
Patent GB-1250262-A (GB)
IPC: F16B21/16
Filed: 1969-04-03
Abstract: 1,250,262. Vehicle wheels. C. H. W. BULLENS AND J. H. BULLENS. 3 April, 1969 [9 April, 1968], No. 17568/69. Heading B7C. A wheel for perambulators, childrens' bicycles and the like comprises a tubular hub 1 with a flange 2 at each end having a tubular extension 4 within the hub to receive a respective bearing bush 6 of resilient synthetic resin, each bush having a flange 7 or 10 contacting flange 2 and each bush being held in its extension by one or more projections 8. Flange 10 supports slidable member 19 spring urged to engage groove 24 in the axle on which the wheel is mounted to prevent axial displacement of the wheel. The flange 10 grips the periphery of the flange 2 via protuberences 22. The outer face of flange 10 is covered with a metal disc 15. In a modification, the flanges are cup-shaped extensions of the hub and welded thereto, and the slidable member is a U-shaped piece of wire each limb being bent to form a neck to engage the axle groove. Specification 1,141,067 is referred to.