baber/WOPTO huggingface dataset:
Patent CA-2545590-A1 (CA)
Inventor: VRIJBLOED JAN WIM
IPC: C07K1/04
Filed: 2003-11-15
Abstract: Template-fixed .beta.-hairpin mimetics of the general formula R1-Cys-Z-Cys-R2 (I) wherein the two Cys residues are bridged by a disulfide bond thereby forming a cyclic peptide; Rl and R2 are preferably Glu-Thr and Thr-Lys; or Lys-Thr and Thr-Glu; or Thr-Glu and Lys-Thr; or Thr-Lys and Glu-Thr; or Leu-Glu and Lys-Val; or Val-Lys and Glu-Leu; or Glu-Leu and Val-Lys; or Lys-Leu and Val-Glu; or Asn-Gly and Lys-Val; or Val-Gly and Lys-Asn; or Gly-Asn and Val-Lys; or Gly-Val and Asn-Lys; or Gly-Gly and Gly-Gly; or Glu-Leu-Lys and Glu-Val-Lys; or Lys-Val-Glu and Lys-Leu-Glu; or Leu-Glu-Lys and Glu-Lys-Val; or Val-Lys-Glu and Lys-Glu-Leu; or Glu-Lys-Leu and Val-Glu-Lys; or Lys-Glu-Val and Leu-Lys-Glu; or Lys-Glu-Leu and Val-Lys-Glu; or Glu-Lys-Val and Leu-Glu-Lys; or Lys-Val-Gly and Gly-Leu-Glu; or Glu-Leu-Gly and Gly-Val-Lys; or Val-Lys-Gly and Gly-Glu-Leu; or Leu-Glu-Gly and Gly-Lys-Val; or Val-Gly-Lys and Glu-Gly-Leu; or Leu-Gly-Glu and Lys-Gly-Val; or Gly-Gly-Gly and Gly-Gly-Gly;  and Z is a chain of n amino acid residues with n being an integer form 4 to 20 and with each of these n amino acid residues being, independently, derived from any naturally occurring L~- .alpha.-amino acid are provided. Libraries comprising a plurality of these templates can be used for the construction of phage display derived template-fixed .beta.-hairpin mimetics generating phage display libraries with very high binding constants to targets, thus combining the advantage of screening of large phage display derived template-fixed .beta.-hairpin libraries which in turn considerably facilitates structure-activity studies, and hence the discovery of new molecules with potent activities and with novel selectivities towards different types of targets.
Patent CA-2548560-A1 (CA)
Title: Steel for structural part of automobile and method for producing the same
Inventor: TOYODA SHUNSUKE
IPC: C21D8/02
Filed: 2004-12-09
Abstract: A method for producing a steel product which comprises providing a steel sla b having a chemical composition satisfying C: 0.18 to 0.29 %, Si: 0.06 to 0.45 %, Mn: 0.91 to 1.85 %, P: 0.019 % or less, S: 0.0029% or less, sol.Al: 0.015 to 0.075%, N: 0.0049 % or less, O: 0.0049 % or less, B: 0.0001 to 0.0029 %, Nb: 0.001 to 0.019 %, Ti: 0.001 to 0.029 %, Cr: 0.001 to 0.195 %, Mo: 0.001 to 0.195 %, and 0.4 or more and less than 0.58 of Ceq, and satisfying that the sum (.chi.) of hardenability multiples according to Grossmann being aware of B is 1.2 or more and less than 1.7, heating the steel slab to 1160 to 1320~C, subjecting the resultant slab to a hot finish rolling having an ending temperature for the finish rolling of 750 to 980~C, annealing the rolled product for a period of 2s or more before winding, and then winding the product up at a temperature of 560 to 740~C, to thereby produce a hot-rolled steel belt which has a structure having an average grain diameter (df) corresponding to a ferrite circle of 1.1 .mu.m or more and less than 12 .mu. m and a ferrite volume percentage (Vf) of 30 to 98 %. A steel pipe is produced by a method comprising using the above hot-rolled steel belt as a material a nd subjecting it to an electric welding wherein a reduction ratio for width is 8 % or less. A steel product produced by the above method is excellent in formability, fatigue strength after hardening, toughness at a low temperatur e, characteristics of resistance to delayed break and corrosion fatigue strengt h.
Patent CA-2549067-A1 (CA)
Inventor: HERTZ THOMAS
IPC: A61M/
Filed: 2005-02-11
Abstract: A biological fluid device (703) comprises a pressure sensor (702), which is arranged on the device. The pressure sensor comprises a compressible container, the compression of which is indicative of the pressure, and is capable of wireless communication.
Patent CA-2553040-A1 (CA)
Inventor: WILSON TROY
IPC: C12Q1/68
Filed: 2005-01-28
Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
Patent CA-2553727-A1 (CA)
Title: Stud sensor with floating head
Inventor: KRANTZ NORMAN L
IPC: G01R19/00
Filed: 2005-02-11
Abstract: A sensor such as a stud sensor having a capacitor plate coupled with a spring to a head to provide a floating head. In other versions, the sensor has an on-switch coupled between a head and a body of a sensor; a head detachable from a body of the sensor; a marking instrument coupled with a lever to a body of a sensor; and a body having one or more low compression and/or low resistance slider pads.
Patent CA-2556232-A1 (CA)
Inventor: AL-YOUSUF AHMED KHALIFA
IPC: G06F17/30
Filed: 2006-08-16
Abstract: The present invention relates to a searching system, and more specifically to a system for obtaining, storing, organizing and locating content in response to a user request. The system interacts with academic and professional research providers to obtain content on a variety of different topics which are stored and made available to users. The content is fully searchable and contains links to other related content.
Patent CA-2557193-A1 (CA)
Title: Process for making rigid polyurethane foams
Inventor: JAVARONE CRISTINA
IPC: C08J9/14
Filed: 2005-03-15
Abstract: Process for making rigid polyurethane or urethane-modified polyisocyanurate foams at an isocyanate index of between 110 and 120 comprising the step of reacting an organic polyisocyanate composition with an isocyanate-reactive composition in the presence of a hydrocarbon as blowing agent wherein the isocyanate-reactive composition contains between 3 and 30 wt% of polyester polyols and between 20 and 50 wt% of polyether polyols derived from aromatic amines, the amounts being calculated on the basis of total isocyanate-reactive compound.
Patent CA-2558474-A1 (CA)
Title: Method and apparatus for receive diversity control in wireless communications
Inventor: BANISTER BRIAN CLARKE
IPC: H04B17/00
Filed: 2005-03-04
Abstract: Receiver diversity in a wireless device is controlled in response to operating conditions, transmission requirements, and control settings. The control of diversity reduces power consumption by enabling receive diversity on given conditions. Operating conditions, transmission requirements, and control settings are used separately or used in conjunction to determine whether benefits of multi-antenna receive diversity, such as higher link capacity, higher data throughput, lower transmit power, and lower error rate, warrant the higher power cost of the diversity.
Patent CA-2559766-A1 (CA)
Inventor: KING RUSSELL STUART
IPC: B05B5/00
Filed: 2005-03-31
Abstract: Published without an Abstract
Patent CA-2561286-A1 (CA)
Inventor: TOMITORI HIDEYUKI
IPC: C12Q1/26
Filed: 2005-03-25
Abstract: It is intended to provide a method of diagnosing apoplectic stroke/asymptomatic brain infarction and screening patients with apoplectic stroke/asymptomatic brain infarction by measuring the acrolein content, the polyamine content, the polyamine oxidase activity or the content of polyamine oxidase protein in the plasma. This finding suggests that inhibition of polyamine oxidase would contribute to the prevention of apoplectic stroke/asymptomatic brain infarction or the halt of the progression of pathological conditions thereof and that a remedy for apoplectic stroke/asymptomatic brain infarction would be obtained by searching for a compound inhibiting polyamine oxidase.
Patent CA-2561349-A1 (CA)
Title: Restriction tolerant packer cup
Inventor: ESPINOSA FRANK
IPC: E21B33/126
Filed: 2005-04-21
Abstract: The present invention relates to a packer cup (5) having a deformable leading edge (20) which moves away from well bore or casing obstructions as the packer cup (5) is moved into a well bore. The anaxisymmetric deformable leading edge (20) can be formed by an angled leading edge (19) which presents only a portion of the leading edge (18) to a well bore obstruction and allows the edge (19) to move past the obstruction with little or no longitudinal force.  Another embodiment provides an anaxisymmetric deformable leading interior edge (72) which is unduloid providing alternatively stiff and deformable sections (74, 76) of the edge (72) to move past the obstructions.
Patent CA-2561555-A1 (CA)
Inventor: CHATTERJEE SANKAR
IPC: C07D211/46
Filed: 2005-04-13
Abstract: The present invention provides compounds of formula (I), wherein the constituent members are defined in the claims, pharmaceutical compositions thereof and methods for treating excessive sleepiness associated with narcolepsy, obstructive sleep apnoea or shift work disorder;  Parkinson's disease; Alzheimer's disease; attention deficit disorder;  attention deficit hyperactivity disorder; depression; or fatigue therewith.
Patent CA-2562068-A1 (CA)
Inventor: SHEDLOV MATT
IPC: B23Q11/08
Filed: 2005-03-17
Abstract: A stent manufacturing device (110) and methods for making intravascular stents and other medical devices. The stent manufacturing device may include a base (124), a laser (112) coupled to the base (124), a horizontal motor (118) coupled to the base (124), and a rotary motor (120) coupled to the horizontal motor (118). A workpiece (16) can be attached to the cutting device, for example adjacent the rotary motor (120), and the workpiece (16) can be cut with the cutting device.
Patent CA-2562081-A1 (CA)
Title: Method for encapsulation of orally ingested materials to alter the site of digestion, site of action, or stability
Inventor: DROUILLARD JAMES S
IPC: A23K1/16
Filed: 2005-04-06
Abstract: Comestible materials encapsulated by a film-forming composition including a plant protein source and methods of forming the same are provided. The film-forming composition affects the site of digestion of the comestible material within the digestive tract of an animal or a human thereby allowing the material to be most effectively utilized by the body. Also, the film-forming compositions maybe used to enhance the stability of the encapsulated material and prevent undesired interaction with other components of a mixture.
Patent CA-2566085-A1 (CA)
Inventor: PAVLOVIC DRAZEN
IPC: C07H17/08
Filed: 2005-05-02
Abstract: The present invention relates to 14- or 15-membered macrolides substituted at the 4~ position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infoections in a human or animal body.
Patent CA-2574494-A1 (CA)
Inventor: RICHARD ROBERT E
IPC: A61M25/10
Filed: 2005-07-19
Abstract: The present invention provides a medical device comprising an electrically conductive substrate and a coating layer that covers at least a portion of the electrically conductive substrate, wherein the coating layer comprises a polymer that is made by a process that comprises (a) electrochemically linking a initiator to a surface of the electrically conductive substrate and (b) conducting a free radical polymerization reaction in the presence of one or more free radical polymerizable monomers.
Patent CA-2575136-A1 (CA)
Inventor: ZIMAN LYNN A
IPC: F16L25/00
Filed: 2005-08-09
Abstract: An adapter that bridges the connecting ends of a medication providing device and a fluid connector includes a housing shroud that is fitted at one end with a core and at its other end with an inner shroud. Once fitted to the housing shroud, the core and the inner shroud each are not removable from the housing shroud. A catch hub is provided within the housing shroud for non-removably maintaining the core to the housing shroud. The core is rotatable relative to the housing shroud. Sufficient friction is provided between the core and the housing shroud to enable the medication providing device to be readily coupled to the core. Once the medication providing device is coupled to the core, and therefore the adapter, additional rotational movement, in either direction, of the medication providing device would only cause the core to rotate freely relative to the housing shroud, thereby preventing the medication providing device such as a syringe from being removed from the adapter. The inner shroud has a catch mechanism that enables it to mate readily with a connector, if the connector is rotated in one direction. The catch mechanism is designed such that once the connector is fully mated to the inner shroud, further rotational movement along the coupling direction would cause the inner shroud to rotate freely relative to the housing shroud. The catch mechanism is further configured to allow the connector to be removed if it were to be turned in a counter rotational direction. The connecting portion of the inner shroud is configured to accept a complementary connector. The connecting portion of the core likewise is configured to accept a complementary connector of the medication providing device to ensure that a proper medication conveying path is established between the medication providing device and the connector, and therefore the patient.
Patent CA-2578953-A1 (CA)
Title: Memantine for the treatment of childhood behavioral disorders
Inventor: MOEBIUS HANS-JOERG
IPC: A61P25/00
Filed: 2005-09-23
Abstract: The present invention provides a method for the treatment of individuals diagnosed with a childhood behavioral disorder such as autistic spectrum disorders or combined type Attention-Deficit/Hyperactivity Disorder (ADHD) by administering an effective amount of memantine.
Patent CA-2579684-A1 (CA)
Inventor: HARPELL WILLIAM
IPC: B66F15/00
Filed: 2007-02-26
Abstract: A pulling tool for grabbing and pulling material from underneath structural elements. The tool has a handle, the handle having a main body portion and having one flat end portion bent from one end of the body portion. A thin, narrow, claw member is attached to the free end of the one end portion and extends across and past both sides of the one end portion to form a claw on each side of the handle at one end of the handle.  Each claw is tapered to a straight end edge which edge is transverse to the end portion. Each claw has a narrow v-shaped material receiving slot extending inwardly from the straight end edge to allow the claw to grab the material being removed.
Patent CA-2579988-A1 (CA)
Title: Liquid co-infusion device
Inventor: KITANI ICHIRO
IPC: A61M5/14
Filed: 2007-02-28
Abstract: A liquid co-infusion device has a plurality of connection ports. The device includes an operating part axially movable within a chamber of the device so as to selectively isolate one of said connection ports from the chamber. An end of the operating part may include a groove or through channel movable to cause such isolation. Preferably, the axial movement of the operating part is guided so as to include a axial movement stop.
Patent CA-2582679-A1 (CA)
Title: Methods and devices for treating multiple-interval well bores
Inventor: EAST LOYD E JR
IPC: E21B43/27
Filed: 2007-03-23
Abstract: Methods and devices are provided for treating multiple interval well bores. More particularly, an isolation assembly may be used to allow for zonal isolation to allow treatment of selected productive or previously producing intervals in multiple interval well bores. One example of a method for treating a multiple interval well bore includes the steps of providing an isolation assembly comprising a liner and a plurality of swellable packers wherein the plurality of swellable packers are disposed around the liner at selected spacings; introducing the isolation assembly into the well bore; allowing at least one of the plurality of swellable packers to swell so as to provide zonal isolation of at least one of a plurality of selected intervals; establishing fluidic connectivity to the at least one of a plurality of selected intervals; and treating the at least one of a plurality of selected intervals.
Patent CA-2588092-A1 (CA)
Inventor: OLIVER JAMES L
IPC: B60W10/08
Filed: 2005-11-16
Abstract: A regeneration and brake management system includes a prime mover (22, 26), an energy storage device (38A, 38B) associated with the prime mover (22, 26), and a regenerative braking system (40) including a controller (32, 34, 35, 36) and at least one friction brake (42, 152, 154, 156, 158), wherein the regenerative braking system (40) is configured to at least partially disable the at least one friction brake (42, 152, 154, 156, 158) during regenerative braking.
Patent CA-2588955-A1 (CA)
Inventor: BOULAVINOV ANDREI
IPC: G01N29/06
Filed: 2005-12-09
Abstract: The invention relates to a method for the non-destructive examination of a test body by means of ultrasound, whereby ultrasound waves are injected into the test body by means of one or more ultrasound transducers and ultrasound waves reflected inside the test body are received by a plurality of ultrasound transducers and are converted to ultrasound signals. The ultrasound signals are detected in individual measurement intervals and are stored individually and are accessible to offline evaluation after termination of the measurements. The inventive method allows to subsequently synthesize any acoustic irradiation angle and focusing in the physically possible volume range of the test body from the stored ultrasound signals by using corresponding reconstruction algorithms, thereby eliminating the need for additional ultrasound measurements.
Patent CA-2589261-A1 (CA)
Title: Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
Inventor: JALAN RAJIV
IPC: A61K31/192
Filed: 2005-11-28
Abstract: The present invention relates to use of ornithine in the manufacture of a medicament for use in combination with at least one of phenylacetate and phenylbutyrate for preventing or treating liver decompensation or hepatic encephalopathy. The invention also relates to use of at least one of phenylacetate and phenylbutyrate in the manufacture of a medicament for use in combination with ornithine for preventing or treating liver decompensation or hepatic encephalopathy.
Patent CA-2590391-A1 (CA)
Inventor: SCHAEFER HANS-LUDWIG
IPC: A61K31/421
Filed: 2005-12-06
Abstract: The invention describes the use of PPAR agonists of the formulae (I) or (II) for the treatment of congestive heart failure (CHF).
Patent CA-2593282-A1 (CA)
Title: Production of fatty acid alkyl esters by use of two lipolytic enzymes
Inventor: ABO MASANOBU
IPC: C12P7/64
Filed: 2006-01-10
Abstract: A method for producing fatty acid alkyl esters, wherein a solution comprising triglyceride and alcohol is contacted with a first lipolytic enzyme having a relatively higher activity on free fatty acids than on triglyceride and a second lipolytic enzyme having a relatively higher activity on triglyceride than on free fatty acids.
Patent CA-2594672-A1 (CA)
Title: Methods and compositions to inhibit p2x7 receptor expression
Inventor: SESTO ANGELA
IPC: C07K14/705
Filed: 2005-08-30
Abstract: Methods and compositions for the downregulation of P2X7 receptor expression or activity are disclosed. Preferred compositions comprise siNA. The methods and compositions are useful in the treatment of diseases characterised by increased P2X7 receptor activity, such as neuronal degeneration, Alzheimer~s disease, inflammatory diseases, and some cancers.
Patent CA-2600238-A1 (CA)
Inventor: CAVANI SILVIA
IPC: B01D65/10
Filed: 2007-09-05
Abstract: A method of testing the integrity of a membrane of at least one filter located along a dialysis solution circuit; the method including, in succession, the steps of:   - wetting the test membrane with an aqueous solution;   - expelling the aqueous solution from the filter;   - filling a fill chamber of the filter with a given quantity of gas, after first closing the gas flow lines from the fill chamber; and - detecting gas flow through the membrane, which bounds the fill chamber.   (Figure 3)
Patent CA-2601092-A1 (CA)
Inventor: DURNEY MAX W
IPC: B32B3/10
Filed: 2006-03-13
Abstract: A method of preparing a sheet of material (421) for bending along a bend line includes the step of forming at least one displacement in the thickness direction of the sheet of material, the displacement including a flat zone (428) substantially parallel to the sheet of material with a portion of the periphery of the flat zone extending along and adjacent to the bend line, and including an angled transition zone (432) interconnecting the flat zone with a remainder of the sheet of material. The forming step is preferably accomplished using one of a stamping process, a punching process (443), a roll forming process and an embossing process. A sheet of material suitable for bending using the process also is disclosed, as are the use of coatings, shin guards and displacing the area of the sheet between bending inducing slits.
Patent CA-2603487-A1 (CA)
Inventor: BOTKIN AMY
IPC: B42F13/04
Filed: 2007-09-19
Abstract: A gift organizer for storing various gift information includes a pair of front and rear covers and two or more sets of pages bound together to the front and rear covers. The sets of pages are provided respectively with pre-printed category indicators each specific to the respective set of pages to designate the respective set of pages for storing gift information of a specific category.
Patent CA-2607224-A1 (CA)
Inventor: LINKLETTER DON R
IPC: B05B9/04
Filed: 2007-10-19
Abstract: A portable grease gun with the capability of being attached to either a grease containing barrel or a hose carrying grease from a grease supply container. An adapter may be mounted to the barrel mounting in place of a barrel to couple the grease gun to a hose connected to a grease supply container remote from the grease gun. Alternating plug may be mounted in the barrel mounting and a pumped grease supply coupled to the resupply port on the grease gun. The grease gun includes an output valve which restrains passage of grease at pressure below 30 psi.
Patent CA-2608741-A1 (CA)
Inventor: RASTOGI MUKUL
IPC: H02J3/18
Filed: 2006-05-16
Abstract: A multi-phase active filter (234) includes a group of power cells (241-252) electrically connected in a three-phase configuration, a precharging circuit (260) , and a controller (350) that controls the voltage delivered to the plurality of power cells (241-252) . Each power cell includes an inverter (300) having a pair of direct current terminals, at least one capacitor (320) electrically connected in parallel with the inverter (300) , and an energy dissipating circuit (330) that is electrically connected in parallel with the inverter (300) . The energy dissipating circuit (330) of each power cell self -regulates DC voltage within the cell.
Patent CA-2609602-A1 (CA)
Title: Semiconductor device comprising a superlattice dielectric interface layer
Inventor: HUANG XIANGYANG
IPC: H01L29/15
Filed: 2006-05-02
Abstract: A semiconductor device may include a semiconductor substrate and at least one active device adjacent the semiconductor substrate. The at least one active device may include an electrode layer, a high-K dielectric layer underlying the electrode layer and in contact therewith, and a superlattice underlying the high-K dielectric layer opposite the electrode layer and in contact with the high-K dielectric layer. The superlattice may include a plurality of stacked groups of layers. Each group of layers of the superlattice may include a plurality of stacked base semiconductor monolayers defining a base semiconductor portion and at least one non-semiconductor monolayer constrained within a crystal lattice of adjacent base semiconductor portions.
Patent CA-2611195-A1 (CA)
Title: Security document
Inventor: SCHILLING ANDREAS
IPC: B42D15/10
Filed: 2006-06-09
Abstract: Described is a security document with a transparent security element (12) which is arranged in a window or in a transparent region of the security document and has a structure layer, in which a first region (12f) of the structure layer has an asymmetrical diffractive relief structure, wherein the first region (12f) has an optical effect which is unexpectedly different in a front view and in a rear view of the security document.