baber/WOPTO huggingface dataset:
Patent NZ-570495-A (NZ)
Title: Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound
Inventor: UCHIDA YUKIO
IPC: C07D231/20
Filed: 2007-02-08
Abstract: Disclosed is a process for the production of 5-alkoxy-4-hydroxymethylpyrazole compounds as represented by the general formula (3); which comprises reacting a pyrazole compound as represented by the general formula (1) with a compound of the formula R3-L in the presence of a base and formaldehyde; wherein R1 is a straight or branched chain alkyl group, a monocyclic or fused ring aryl group, a monocyclic or fused ring heteroaryl group having at least one hetero atom selected from nitrogen atom and sulfur; R2 is an electron withdrawing group selected from straight or branched chain haloalkyl groups; COOH; carboxyl group metal salts typified by alkali metal salts or alkaline earth metal salts; (straight or branched chain alkoxy)carbonyl groups; halogen atoms; nitro; formyl groups; (straight or branched chain alkyl)carbonyl groups; arylcarbonyl groups; monocyclic or fused ring heteroarylcarbonyl groups having one to four hetero-atoms selected from nitrogen, oxygen and sulfur; amino carbonyl groups; mono- or di(straight or branched chain alkyl)aminocarbonyl groups; and cyano; R3 is an optionally substituted alkyl, cycloalkyl, cycloalkylalkyl, alkenyl or an alkynyl group (as defined herein); and L is a leaving group. ;
Patent NZ-572907-A (NZ)
Title: Raised end fertilizer transport trailer
Inventor: GLASGOW THOMAS STEWART
IPC: B60P1/04
Filed: 2008-11-19
Abstract: A fertilizer transport trailer 1 is provided with a container 2 having an outlet at an end 3 from which fertilizer can be dispensed into a spreader hopper and a "mover" such as a belt conveyor 11 to shift the fertilizer between the interior of the container and the outlet. A lifting arrangement 14, 15 is effective to raise the outlet end of the container and draw the wheels 5 of the trailer toward a medial portion of the trailer to leave a clear space beneath the outlet end so that the fertilizer can be dispensed from the outlet into a hopper when the end of the container is raised.
Patent NZ-573194-A (NZ)
Title: A non-multifocal contact lens comprising a central optical zone and a peripheral optical zone
Inventor: HOLDEN BRIEN ANTHONY
IPC: G02C7/04
Filed: 2007-06-05
Abstract: Disclosed is a non-multifocal contact lens (10) for an eye (14). The contact lens (10) comprises a central optical zone (20) and a peripheral optical zone (24). The central optical zone (20) has a dimension of at least 3.8mm. The central optical zone (20) has a central zone refractive power that is adapted to provide the wearer with clear vision in a central region (32) of the retina (34) of the eye (14). The peripheral optical zone (24) is disposed radially outward from the central zone (20). The peripheral optical zone (24) has a peripheral optical zone refractive power. This peripheral optical zone refractive power is greater than the central optical zone refractive power by an amount that is sufficient to focus the off-axis rays (54) entering the eye (14) through the peripheral optical zone (24) when the lens (10) is worn. The off-axis rays (54) are focussed onto the points on or anterior to a peripheral region (44) of the retina (34) that is located around its central region (32).
Patent NZ-583148-A (NZ)
Title: Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt
Inventor: KIM SOOJIN
IPC: A61K31/4178
Filed: 2008-07-31
Abstract: The present disclosure relates to a crystalline form of methyl ((1S)-1-(((2S>2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The disclosure also relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.
Patent NZ-584594-A (NZ)
Title: Hand held micro pcr device
Inventor: KUMAR KISHORE KRISHNA
IPC: B01L7/00
Filed: 2008-10-13
Abstract: A hand held micro PCR device comprises a) a low temperature co-fired ceramic (LTCC) micro PCR chip comprising a heater, a reaction chamber to load a sample, b) a heater control to regulate the heater on basis of input received from a temperature sensor, c) an optical detection system to detect a fluorescence signal from the sample, and d) at least one communication interface to interact with other device(s). The other device is selected from group comprising smart phone, PDA and programmable device which collects temperature of the chip and the amplified signal from the hand held device. The temperature sensor can be placed outside the chip or embedded in at least one layer of the chip to measure temperature of the chip. The optical detection system can comprises a light source and a photo detector and the optical detection system is selected from the group comprising of a beamsplitter optical detection system, a hybrid optical detection system and bifurcated optical detection system.
Patent NZ-587189-A (NZ)
Title: Heterocyclic inhibitors of MEK and methods of use thereof
Inventor: MARLOW ALLISON L
IPC: C07D237/12
Filed: 2006-05-17
Abstract: Disclosed is a compound of formula (V) where the variables are as disclosed in the description. Examples of compound of formula (IV) are 5-fluoro-2-(2-fluoro-4-(methylthio) phenylamino )-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide and (S)-5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-N-(2-hydroxypropoxy)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide. Also disclosed is the use of a compound of formula (V) in the manufacture of a medicament for treating herperproliferative disorders or inflammatory conditions; a method of producing a MEK inhibitory effect in a warm-blooded non-human animal; a pharmaceutical composition comprising a compound of formula (V) and the method of preparing a compound of formula (V).
Patent NZ-588779-A (NZ)
Title: Substituted 4-aminocyclohexane derivatives
Inventor: NOLTE BERT
IPC: A61K31/137
Filed: 2009-03-25
Abstract: Disclosed are 4-aminocyclohexane derivatives represented by general formula (I). Examples of the compound of formula (I) include: 1-(imino(1-methyl-1H-indol-2-yl)methyl)-N1,N1,N4,N4-tetramethyl-4-phenylcyclohexane-1,4-diamine bis(2-hydroxypropane-1,2,3-tricarboxylate); 1,4-bis(dimethylamino)-4-phenylcyclohexyl)(1-methyl-1H-indol-2-yl)methanone; N1,N1,N4,N4-tetramethyl-1,4-diphenylcyclohexane-1,4-diamine; The compounds of formula (I) are used to treat pain.
Patent NZ-589957-A (NZ)
Title: Beverages with enhanced flavors and aromas and method of making same
Inventor: ROBINSON URANO A
IPC: A23L33/15
Filed: 2009-02-19
Abstract: A method of making a soluble coffee product is disclosed, which comprises: the steps of:(i) pulverizing coffee beans to form a first pulverized coffee product,(ii) grinding or pulverizing coffee beans to form a second ground or pulverized coffee product,(iii) extracting the second ground or pulverized coffee product to form an extracted coffee product and spent coffee grounds,(iv) combining a first portion of the first pulverized coffee product with the extracted coffee product to form a first coffee blend, (v) drying the first coffee blend to form a first dried coffee blend, (vi) combining a second portion of the first pulverized coffee product with the first dried coffee blend to form the soluble coffee product.
Patent NZ-590437-A (NZ)
Title: 6-substituted phenoxychroman carboxylic acid derivatives
Inventor: BURGESS LAURENCE E
IPC: C07D405/12
Filed: 2009-06-24
Abstract: Disclosed is a phenoxychroman carboxylic acid derivative of formula I, or a salt of the compound, wherein the substituents are as defined in the specification. These compounds are described as DP2 receptor antagonists. Also disclosed is the use of the compound for treating an immunologic disorder. Also disclosed is a method of synthesising the compound, and intermediates useful for that synthesis.
Patent NZ-591595-A (NZ)
Title: Device and method for combining two sources of water with different pressures
Inventor: WRIGHT ANTHONY
IPC: E03B1/04
Filed: 2009-08-31
Abstract: Disclosed is a device which allows any tank collected rainwater to be utilised automatically with a reticulated water supply. The device comprises a hollow substantially T-shaped body having a first inlet and a first outlet. An integral hollow leg of the T-body terminates with a second inlet. A hose or pipe leading from a source (TW) of tank water is connected to the inlet. One end of an internal bore (11) of a hollow cylindrical body (12) has a jet (13) attached. The body is connected to the inlet. The other end of the body is plumbed in to a source of reticulated water (RW). The position of the jet within the body can be varied. The reticulated water is restricted to pass through first the body and then the jet. A hollow cylindrical body (19) incorporates a venturi (20). The body is connected to the outlet. The other end of the body (19) is plumbed back in to the piping associated with the source of reticulated water. The position of the body can be varied. The reticulated water, and any tank water within the body, is restricted to pass through the venturi. Upon activation, the flow of reticulated water into the body is restricted by passing through the jet. As the pressure within the body is consequently lowered at the exit of the jet, any rainwater is drawn from the rainwater tank through the hose or pipe into the body to be combined with the reticulated water in the body before passing through the venturi.
Patent NZ-592511-A (NZ)
Title: Amine salts of { 4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl} acetic acid
Inventor: LY TAI WEI
IPC: A61K31/33
Filed: 2008-06-18
Abstract: Disclosed is an amine salt of the compound of Formula (I), { 4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl} acetic acid. Also disclosed is the use of the salt to treat CRTH2-mediated diseases, eosinophil-related diseases, basophil-related diseases, or inflammatory diseases, such as asthma, allergic asthma, exercise induced asthma, allergic rhinitis, perennial allergic rhinitis, seasonal allergic rhinitis, atopic dermatitis, contact hypersensitivity, contact dermatitis, conjunctivitis, allergic conjunctivitis, eosinophilic bronchitis, food allergies, eosinophilic gastroenteritis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, mastocytosis, hyper IgE syndrome, systemic lupus erythematous, psoriasis, acne, multiple sclerosis, allograft rejection, reperfusion injury, chronic obstructive pulmonary disease, Churg-Strauss syndrome, sinusitis, basophilic leukemia, chronic urticaria, basophilic leukocytosis, psoriasis, eczema, COPD (chronic obstructive pulmonary disorder), arthritis, rheumatoid arthritis, psoriatic arthritis, and osteoarthritis.
Patent NZ-597142-A (NZ)
Title: Pre-Combustion Cycle Pressurisation System using a pivoting flap valve
Inventor: MCLACHLAN PAUL ANTHONY
IPC: F01C9/00
Filed: 2010-05-10
Abstract: 597142 A two stroke internal combustion engine (1) incorporating an asymmetric exhaust port/transfer port inversion device (2) is disclosed. The asymmetric exhaust port/transfer port inversion device is characterised in that it includes a hollow flap valve (100) adapted to pivot about a hollow pivot shaft (101) between a closed position and an open position wherein pivoting the device to the open position as the piston (3) begins the compression stroke allows the transfer of air to continue after the leading edge of the piston has closed off the exhaust port (105) thereby advancing the timing of the exhaust port closing and extending the duration of air transfer from the crankcase primary compression chamber (103).
Patent NZ-606828-A (NZ)
Title: Human binding molecules having killing activity against enterococci and staphylococcus aureus and uses thereof
Inventor: KRAMER ROBERT A
IPC: A61K39/116
Filed: 2007-06-05
Abstract: Disclosed is a human monoclonal antibody, wherein said antibody comprises: - a heavy chain CDR1 region comprising amino acid sequence SEQ ID NO: 55; - a heavy chain CDR2 region comprising amino acid sequence SEQ ID NO: 56; - a heavy chain CDR3 region comprising amino acid sequence SEQ ID NO: 57; - a light chain CDR1 region comprising amino acid sequence SEQ ID NO: 58; - a light chain CDR2 region comprising amino acid sequence SEQ ID NO: 59; and - a light chain CDR3 region comprising amino acid sequence SEQ ID NO: 60; characterised in that said antibody has opsonic phagocytic killing activity against at least one strain of each of at least two different Enterococcus species and against at least one strain of Staphylococcus aureus, wherein the sequences are as defined in the complete specification. Also disclosed is the use of said antibody in the manufacture of a medicament for the diagnosis, prophylaxis, treatment, or combination thereof, of an enterococcal infection and/or a staphylococcal infection.
Patent NZ-613812-A (NZ)
Title: Compositions and methods for treating chronic inflammation and inflammatory diseases
Inventor: BREW JOHN
IPC: A61P37/00
Filed: 2012-02-03
Abstract: Provided are pharmaceutical compositions comprising a therapeutic compound with anti-inflammatory activity, a pharmaceutically acceptable solvent and a pharmaceutically acceptable adjuvant. Exemplified therapeutic compounds include ibuprofen, gemfibrozil and naproxen. Further provided are methods of treating inflammatory diseases or conditions using the compositions.
Patent NZ-618140-A (NZ)
Title: Surface machining apparatus
Inventor: BACKHOUSE ANTHONY EDWARD
IPC: B23B29/32
Filed: 2012-05-10
Abstract: An apparatus for machining a surface of a workpiece, the apparatus including a support structure, a facing arm having a machining element 4 which is movable along an axis of the facing arm 14 thereby to position the machining element 4 relative to the surface of the workpiece, and electrically powered drive 9, 10, 11, 12, 13 for moving the machining element along the axis of the facing arm, and a computerised control module coupled to the electrically powered drive 9, 10, 11, 12, 13 and operably couplable to a remote control module 1 for wirelessly receiving instructions to operate the drive 9, 10, 11, 12, 13. The facing arm is mounted to a spindle of the support structure for rotational motion about the spindle.
Patent NZ-618936-A (NZ)
Title: Indene derivatives for use in the treatment of inflammatory bowel disease
Inventor: SHERIDAN HELEN
IPC: C07C65/19
Filed: 2012-07-20
Abstract: Disclosed are indene compounds of the structural formula (I) and their N-Methyl-(D)-Glucamine salts. Also disclosed is the use of said compounds for treating inflammatory bowel disease including Crohn’s disease and ulcerative colitis. Examples of compounds of formula (I) are: 4-((-1-hydroxy-2,3-dihydro-1H,1’H-2,2’-biinden-2-yl)methyl)benzoic acid 6-(Methylamino)hexane-1,2,3,4,5-pentanol 4-(((1S,2S)-1-hydroxy-2,3-dihydro-1H,1’H-2,2’-biinden-2-yl)methyl)benzoate (S)-1-Phenylethylammonium 4-(((1S,2S)-1-hydroxy-2,3-dihydro-1H,-1’H-2,2’-biinden-2-yl)methyl)benzoate
Patent NZ-702310-A (NZ)
Title: Engineered botulinum neurotoxin
Inventor: DONG MIN
IPC: C07K14/33
Filed: 2013-03-13
Abstract: Disclosed herein are botulinum neurotoxin (BoNT) polypeptides with a modified receptor binding domain of Clostridial botulinum serotype B (B-Hc), comprising one or more substitution mutations corresponding to substitution mutations in serotype B, strain 1, V1118M; Y1183M; E1191M; E1191I; E1191Q; E1191T; S1199Y; S1199F; S1199L; S1201V; or combinations thereof. Specific combination mutations include E1191M and S1199L, E1191M and S1199Y, E1191M and S1199F, E1191Q and S1199L, E1191Q and S1199Y, or E1191Q and S1199F. Other substitution mutations are also disclosed. Isolated modified receptor binding domains, chimeric molecules, pharmaceutical compositions, and methods of using the same are also disclosed.
Patent NZ-706865-A (NZ)
Title: Solid form of dihydro-pyrido-oxazine derivative
Inventor: SOLDERMANN NICOLAS
IPC: C07D498/04
Filed: 2013-11-26
Abstract: The invention relates to an anhydrous crystalline form of (1,1-dioxo-hexahydro-1lambda*6*- thiopyran-4-yl)-{ (S)-3-[1-(6-methoxy-5-methyl-pyridin-3-yl)-2,3-dihydro-1H-pyrido[3,4- b][1,4]oxazin-7-yloxy]-pyrrolidin-1-yl} -methanone; pharmaceutical compositions and combinations including these forms as well as to methods of using these forms, including their pharmaceutical compositions and combinations for the treatment of diseases.
Patent NZ-709639-A (NZ)
Title: Audio frame loss concealment
Inventor: BRUHN STEFAN
IPC: G10L19/005
Filed: 2014-01-22
Abstract: The invention relates to a method of concealing a lost audio frame of a received audio signal by extracting a segment from a previously received or reconstructed audio signal, wherein the segment is used as a prototype frame in order to create a substitution frame for a lost audio frame; transforming the extracted prototype frame into a frequency domain representation; performing a sinusoidal analysis of the prototype frame by identifying frequencies of sinusoidal components of the audio signal; changing all spectral coefficients of the prototype frame included in an interval Mk around a sinusoid k by a phase shift proportional to the sinusoidal frequency fk and the time difference between the lost audio frame and the prototype frame; changing the phase of a spectral coefficient of the prototype frame not included in any of the intervals related to a region around the identified sinusoids by a random value, and retaining the magnitude of that spectral coefficient; and performing an inverse frequency domain transform of the phase adjusted frequency spectrum of the prototype frame thereby creating the substitution frame for the lost audio frame. The invention also relates to decoders, a receiver, a computer program and a computer program product related to the method.
Patent NZ-715344-A (NZ)
Title: Sensor apparatus and associated systems and methods
Inventor: SHARPE JOHNATHAN
IPC: G01P15/08
Filed: 2014-05-20
Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
Patent NZ-722357-A (NZ)
Title: A portable compression device
Inventor: RAMAKRISHNA RAJ
IPC: A61H9/00
Filed: 2015-02-06
Abstract: The present invention provides a portable compression device (10) for selectively applying a compressive force to a limb of a user (50). The device includes one or more inflatable bladders (18, 20, 22) and a pumping means (24, 26, 28) for selectively inflating and deflating each bladder thereby selectively applying an inwardly directed compressive force to the limb. The one or more inflatable bladders and the pumping means are disposed on a base assembly (12). The present invention aims to reduce the size and weight compared to existing products, and to ease usability compared to compression stockings and also different pressures can be applied by the separate bladders using the control device. Problems addressed include cumbersome non-ambulatory machines for such therapy or elderly difficulties in using other types of apparatus.
Patent NZ-723650-A (NZ)
Title: Mattress arrangement, such as a bed, having adjustable firmness
Inventor: HÄGER BENGT
IPC: A47C23/043
Filed: 2015-03-26
Abstract: A mattress arrangement, such as a bed arrangement (1), having adjustable firmness is disclosed. The mattress arrangement comprises an upper mattress (3) and a lower mattress (4) being arranged beneath said upper mattress (3). At least one side (41) of the lower mattress (4) is moveable in relation to an opposite side (42) of the lower mattress (4), the lower mattress (4) thereby being expandable into an expanded state, having a lower firmness, and compressible into a contracted state, having a higher firmness. A support layer (6) is arranged between the upper mattress (3) and the lower mattress (4), to partly support the upper mattress (3), and arranged overlying the at least one moveable side (41) of the lower mattress (4). Hereby, at least one compartment is formed beneath the upper mattress (3), wherein the compartment(s) is at least partly empty when the lower mattress (4) is in the contracted state and at least partly filled when the lower mattress (4) is in the expanded state. A problem this invention solves is to be able to have different levels of firmness for different parts of the body when lying on the mattress.
Patent NZ-728172-A (NZ)
Title: Low water coffee and tea beverage concentrates and methods for making the same
Inventor: RAGNARSSON KARL
IPC: A23F3/16
Filed: 2015-07-02
Abstract: Low water liquid beverage concentrates and methods for making the concentrates are provided herein. The concentrates include a high coffee and/or tea solids content and total solids content. The amounts of water, total solids, and coffee and/or tea solids are effective to provide a low water beverage concentrate having a pH between about 3.0 to about 6.0. In some approaches, the pH of the low water beverage concentrate changes fewer than about 0.5 pH units after at least three months storage at 70F in a closed container. The low water beverage concentrates provide a desired flavor profile with little or no flavor degradation after storage at 70F in a closed container for at least about three months. Methods for making the low water beverage concentrates are also provided.
Patent NZ-750252-A (NZ)
Title: Sulfonamides as gpr40- and gpr120-agonists
Inventor: DE PIZZOL MARIA
IPC: C07D231/42
Filed: 2017-08-07
Abstract: The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I). Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GPR40 such as diabetes (particularly type 2 diabetes), impaired oral glucose tolerance, insulin resistance, obesity, obesity related disorders, metabolic syndrome, dyslipidemia, elevated LDL, elevated triglycerides, obesity induced inflammation, osteoporosis and obesity related cardiovascular disorders.
Patent NZ-757553-A (NZ)
Title: Sealing web
Inventor: SIMONIS UDO
IPC: B32B27/08
Filed: 2018-05-09
Abstract: The invention relates to a multi-layer sealing web (10) for a region of a structure, said sealing web comprising: outer layers (14, 22, 24), which contain a base polymer and a plasticizer; and a combination carrier insert (16), which contains a glass nonwoven (20) and a glass reinforcement (18), the plasticizer being a low-molecular-weight plasticizer, the proportion of which in the outer layers (14, 22, 24) containing the base polymer being between 25 wt% and 40 wt%. The invention is based on developing a sealing web of a known type for cost-effective production, high dimensional stability and low shrinkage characteristics. Other advantages are discussed in the specification.