baber/WOPTO huggingface dataset:
Patent WO-2021050829-A1 (WO)
Title: Neuromodulation of the glossopharyngal nerve to improve sleep disordered breathing
Inventor: KENT DAVID T
IPC: A61N1/36
Filed: 2020-09-11
Abstract: Methods and systems are provided to improve SDB in a patient suffering therefrom by delivering an electrical neuromodulation signal to at least a target site comprising an efferent fiber of the glossopharyngeal nerve that innervates pharyngeal constrictor muscles or the stylopharyngeus muscle. Methods include further delivering electrical neuromodulation signals to other sites including one or more combinations of the ansa cervicalis, the hypoglossal nerve, the palatoglossus muscle, and/or the palatopharyngeus muscle. The electrical neuromodulation signal delivered to efferent fibers of the glossopharyngeal nerve can be done independent of a detected sensory or input signal that measures the neuromuscular state of the patient's airway.
Patent WO-2021055612-A1 (WO)
Inventor: SKERLJ RENATO
IPC: A61P25/28
Filed: 2020-09-17
Abstract: L'invention concerne des imidazole carboxamides substitués et des composés associés, des compositions contenant de tels composés, des kits médicaux et des procédés d'utilisation de tels composés et compositions pour traiter un trouble médical, par exemple, un cancer, un trouble de stockage lysosomal, un trouble neurodégénératif, un trouble inflammatoire, chez un patient.
Patent WO-2021076704-A1 (WO)
Inventor: RAKHUNDE VIKAS
IPC: E21B33/03
Filed: 2020-10-15
Abstract: A system an annular sleeve configured to be positioned in an annular space between a first annular component and a second annular component of a drilling system. The annular sleeve includes a radially-inner annular surface and a radially-outer annular surface. The annular sleeve also includes a first annular seal element coupled to the radially-inner annular surface and configured to seal against the first annular component, a second annular seal element coupled to the radially-outer annular surface and configured to seal against the second annular component, and one or more axially-extending passageways extending from a first end to a second end of the annular sleeve. The annular sleeve is configured to direct a fluid flow through the one or more axially-extending passageways across the annular sleeve.
Patent WO-2021076878-A1 (WO)
Inventor: SEVINDIK VOLKAN
IPC: G06F15/173
Filed: 2020-10-16
Abstract: An aspect includes a method for use with a mobile communications device comprising a plurality of subscriber identification modules sharing a cache. The method includes a first subscriber identification module authenticating with and connecting to the network, followed by a second subscriber identification module authenticating with and connecting to the network. The method also includes, while the first subscriber identification module is requesting and receiving first data from the network and storing the first data in the cache, the second identification module requesting and receiving second data from the network and storing the second data in the cache. The method further includes an application executing on the device retrieving and processing at least a portion of the first and second data stored in the cache, while at least one of the first and second subscriber identification modules is storing additional data received from the network in the cache.
Patent WO-2021108165-A1 (WO)
Inventor: BUSAM JONATHAN
IPC: A61M39/06
Filed: 2020-11-17
Abstract: The present application discloses medical instruments that utilize self-healing polymers as all or portion of the valves and valve assemblies thereof, such that these valves can self-heal while or after being punctured by an ancillary device during a surgical procedure and thereby help minimize blood loss and achieve hemostasis.
Patent WO-2021113585-A1 (WO)
Inventor: ROSS RUSSELL FREDERICK
IPC: A61M37/00
Filed: 2020-12-04
Abstract: Methods, devices and systems for delivery of an anti-PD-1 or an anti-PD-L1 therapeutic agent to the lymphatic system for treating cancer in a patient are described.
Patent WO-2021133541-A1 (WO)
Title: Films d'électrode transmettant la lumière transférable pour dispositifs électro-optiques
Inventor: MURARI NISHIT
IPC: G02F1/16766
Filed: 2020-12-07
Abstract: L'invention concerne un dispositif électro-optique, et son procédé de fabrication, comprenant une première couche de substrat, un film conducteur comprenant une première couche adhésive et une première couche d'électrode, une couche de matériau électro-optique et une seconde couche d'électrode. La première couche d'électrode, qui est en contact avec la couche de matériau électro-optique, comprend un matériau conducteur, tel que des particules conductrices, un matériau métallique ou un polymère conducteur. La première couche adhésive a un module de stockage élevé et ne présente pas de flux de matière plastique dans les conditions de fabrication, de stockage et de fonctionnement du dispositif électro-optique. Le film conducteur ne se conforme pas à la rugosité de surface de la première surface de la couche de matériau électro-optique. Le film conducteur peut être conçu pour être mince, flexible et transparent. Le dispositif électro-optique ainsi obtenu présente d'excellentes performances électro-optiques, même lorsque la couche de matériau électro-optique présente des imperfections sous la forme d'espaces.
Patent WO-2021141859-A1 (WO)
Title: Method for diagnosing and treating asthma by detecting or regulating a panel of internal lipid species
Inventor: HUANG SHAU-KU
IPC: C07F9/10
Filed: 2021-01-04
Abstract: The present invention provides a method for diagnosing asthma by using a panel of internal lipid species, including LPE 22:6, LPE 20:4, SM 16:0, PE 16:0/22:6, PE 18:0/22:6, PE 18:0/20:4 PE 18:0/18:2, and phosphatidylcholine (PC) 18:0/18:2, comprising comparing a cutoff ratio value of the panel of internal lipid species with internal lipid species ratio value for diagnosing. The present invention also provides a method for treating asthma, comprising administrating a therapeutically effective amount of a LEP 22:6 inhibitory regulator, bovine serum albumin or human serum albumin to a subject in need thereof.
Patent WO-2021154573-A1 (WO)
Inventor: LUEBKE CHARLES P
IPC: C10G63/00
Filed: 2021-01-21
Abstract: Des procédés améliorés de production d'essence avec 95 RONC comprenant une zone d'isomérisation en C5-C6, deux zones d'isomérisation en C7 et une zone de reformage sont décrits. Les première et seconde zones d'isomérisation en C7 partagent un stabilisateur commun qui coupe les chlorures et élimine les extrémités légères. Les coûts d'investissement et de fonctionnement des procédés sont réduits par la suppression de l'une des colonnes de stabilisateur et du condenseur, du récepteur, du refroidisseur d'assiette et du rebouilleur associés. Les procédés améliorent le RONC du produit d'isomérisation en C7 car le méthylcyclohexane non converti est recyclé vers la seconde zone d'isomérisation en C7 afin d'être converti en diméthylcyclopentane.
Patent WO-2021154594-A1 (WO)
Title: Dram-based lidar pixel
Inventor: HENDERSON ROBERT
IPC: G01S7/484
Filed: 2021-01-22
Abstract: A Light Detection and Ranging (LIDAR) detector circuit includes a memory device comprising a non-transitory storage medium that is configured to store data indicative of detection events in respective memory bins, and at least one control circuit. The at least one control circuit is configured to receive detection signals from one or more photodetector elements, identify a presence or an absence of detection events indicated by the detection signals during a portion of time between pulses of an emitter signal output from a LIDAR emitter element, and execute one of a first memory operation or a second memory operation to update the data in the respective memory bins responsive to identification of the presence or the absence of the detection events, respectively. Related circuits and methods of operation are also discussed.
Patent WO-2021163472-A1 (WO)
Title: Monitoring viability of organs for transplantation
Inventor: TESSIER SHANNON N
IPC: A61K45/00
Filed: 2021-02-12
Abstract: Methods for monitoring the viability of a donor organ before and after transplant based on detection and analysis of whole cells released from the organs.
Patent WO-2021206830-A1 (WO)
Inventor: WANG HUA
IPC: H04L5/00
Filed: 2021-03-03
Abstract: D'une manière générale, divers aspects de la présente divulgation se rapportent aux communications sans fil. Selon certains aspects, une station de base peut déterminer une quantité totale estimée de ressources pour une ou plusieurs retransmission(s) de communications entre la station de base, un dispositif de commande et un dispositif, la/les retransmission(s) étant associée(s) à une ou plusieurs transmission(s) entre au moins deux éléments parmi la station de base, le dispositif de commande ou le dispositif ; et transmettre, à au moins l'un du dispositif de commande ou du dispositif, une indication d'une attribution de ressources, au moins en partie sur la base de la quantité totale estimée de ressources pour la/les retransmission(s).
Patent WO-2021178696-A1 (WO)
Inventor: BERRADA MARWAN
IPC: A61B17/3207
Filed: 2021-03-04
Abstract: The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include an imaging element at the distal portion, an illumination source at the distal portion, a capture element at the distal portion and configured to engage the thrombus, a fluid delivery mechanism within the lumen and configured to apply fluid to (1) at least partially fragment the thrombus and (2) provide an optical path for the imaging element, and an aspiration mechanism fluidly coupled to the lumen and configured to aspirate the fragmented thrombus.
Patent WO-2021195055-A1 (WO)
Title: Rmn à émission stimulée de faible puissance utilisant des transitions rabi pour la détection de molécules
Inventor: APOSTOLOS JOHN T
IPC: G01N24/08
Filed: 2021-03-23
Abstract: L'invention concerne un système à haute vitesse, basé sur un portique, qui peut identifier rapidement la présence de virus tels que le COVID-19 et ses anticorps in vivo. Le système utilise un effet de résonance magnétique nucléaire (RMN) à émissions stimulées de faible puissance et un traitement du signal associé pour détecter la présence de substances organiques caractéristiques du virus (telles que 15N, 14N, 1H, et/ou 13C). Le portique de détection permet un dépistage non invasif, en temps réel et à faible coût. La détection peut être faite de manière fiable in vivo lorsque le virus ou l'anticorps est présent dans la salive, le thorax, les poumons ou d'autres organes à des comptes totaux aussi bas que 108 copies par ml.
Patent WO-2021195594-A1 (WO)
Inventor: VALAFAR FARAMARZ
IPC: A61K39/04
Filed: 2021-03-26
Abstract: Dans certains modes de réalisation, l'invention concerne des produits de fabrication et des kits, ainsi que des méthodes, qui comprennent ou comprennent l'utilisation de molécules inhibitrices pour le traitement ou l'amélioration, ou la fourniture d'une aide à la décision clinique pour le traitement d'une infection bactérienne, par exemple, une infection à   Mycobacterium tuberculosis  (MTB), ou une infection par n'importe quel membre du complexe M.  tuberculosis  (MTBC). Dans certains modes de réalisation, les molécules inhibitrices inhibent l'expression d'un ou de plusieurs des gènes de MTB 38 PE/PPE tels qu'identifiés dans la description, ou d'un ou de plusieurs des 366 gènes de MTB identiques et protéines communs à un ensemble global d'isolats de MTB tels qu'identifiés dans la description, ou les molécules inhibitrices inhibent l'expression d'un transcrit ou d'un produit génique polypeptidique de ce dernier, ou inhibent le changement (et par conséquent l'évitement du système immunitaire) d'un ou de plusieurs des 52 gènes spéciaux PE/PPE de MTB d'évitement du système immunitaire tels qu'identifiés dans la description.
Patent WO-2021202477-A1 (WO)
Title: Systems, methods, and kits for diagnostics and treatment of viral respiratory infection
Inventor: GOREN OFER A
IPC: G01N33/569
Filed: 2021-03-30
Abstract: The present disclosure includes methods, systems, kits and compositions for treating, preventing and diagnosing viral infections, specifically SARS-CoV-2 infections, with an anti-androgen and anti-thyroid medication, a thyroid receptor antagonist, a TGF-β inhibitor or a combination thereof. The present disclosure also describes methods and compositions for the treatment of viral respiratory diseases, specifically SARS-CoV-2 infections, including anti-androgens, anti-thyroid medications, thyroid receptor antagonists, TGF-β inhibitors, RXR inhibitors, furin inhibitors or other agents to disrupt the androgen signaling.
Patent WO-2021216327-A1 (WO)
Inventor: GLICKMAN JOEL I
IPC: A61F13/38
Filed: 2021-04-14
Abstract: A medical swab comprising a unitary molding of plastic material, such as nylon or polyester, is configured to form an elongated stem and an enlarged tip portion at one end extremity of the stem. The enlarged tip portion is provided with a plurality of recesses in its outer surface for the reception and containment of biological material. The recesses are formed in two groups located on two opposing sides of said tip portion to accommodate production by molding.
Patent WO-2021211796-A1 (WO)
Title: Stable diglyceride emulsions and methods for treating organ injury
Inventor: DECKELBAUM RICHARD J
IPC: A61K31/231
Filed: 2021-04-15
Abstract: The present invention provides compositions and methods involving stable omega-3 diglyceride oil-in-water emulsions for acute therapy to treat and/or prevent tissue or organ injury. The compositions provide protection from cellular death, and find use in patients in need of neuroprotection. For example, the compositions find use in treating ischemia reperfusion injuries, such as ischemic stroke. The compositions further find use for treatment of traumatic injuries, such as traumatic brain injury or spinal cord injury, among others. The compositions have a large time window by which they are effective after onset of traumatic or ischemic injury (e.g., after onset of stroke), and may be administered in conjunction with other therapies.
Patent WO-2021216383-A1 (WO)
Title: Fusionnement de capteurs de température et d'ultrasons pour détection biométrique
Inventor: LIANG YUE
IPC: G06F3/041
Filed: 2021-04-16
Abstract: Un exemple de procédé de fonctionnement peut consister à détecter un contact d'utilisateur dans une première zone en fonction de données de capteur provenant d'un ou de plusieurs capteurs d'un premier type ; à activer un ou plusieurs capteurs d'un second type, conçus pour mesurer à travers une partie ou la totalité de la première zone en réponse à la détection ; à obtenir des données supplémentaires de capteur provenant du ou des capteur(s) du second type ; et à déterminer un emplacement associé au contact de l'utilisateur en fonction en partie des données de capteur provenant du ou des capteur(s) du second type.
Patent WO-2021225793-A1 (WO)
Title: Methods and apparatus for concurrent operation of sps receiver and wireless transmitter
Inventor: COOKMAN JORDAN
IPC: G01S19/21
Filed: 2021-04-22
Abstract: A mobile device may be configured to perform concurrent Satellite Positioning System (SPS) operation and wireless communications when uplink signals transmitted by the mobile device interferes with the reception of SPS signals in one or more frequency bands. The mobile device may determine if the SPS receiver has already acquired SPS signals and is in a tracking state. If the SPS receiver is not in a tracking state, an SPS acquisition procedure is initiated before the wireless communication session is initiated. The SPS acquisition procedure is performed until the SPS receiver reaches a tracking state, or until a timeout is reached. Once the SPS receiver is in a tracking state, the wireless communication session may be initiated, during which the SPS receiver is controlled, e.g., to perform signal blanking, measurement exclusion, or disable SPS reception, to mitigate interference with SPS signals.
Patent WO-2022231583-A1 (WO)
Title: Water saturation and cation exchange capacity from logging-while-drilling electromagnetic measurements
Inventor: ZHANG PING
IPC: G01N27/04
Filed: 2021-04-28
Abstract: A method for characterizing a subterranean formation is provided that involves obtaining resistivity log data measured by a logging-while-drilling electromagnetic tool operated while drilling a wellbore that traverses the subterranean formation, and calculating at least one of a first data value representing water saturation of the subterranean formation and a second data value representing cation exchange capacity (CEC) of the subterranean formation from the resistivity log data. In embodiments, the method can further involve storing at least one of the first data value and the second data value in computer memory, and/or outputting at least one of the first data value and the second data value as part of a log for well placement, formation evaluation, geological modeling, or reservoir management. The first data value and/or the second data value can also be used for geo-steering the drilling of the wellbore.
Patent WO-2021226319-A1 (WO)
Title: Vehicle battery jump starter with multiple battery pack compatibility
Inventor: WOOD STEVEN
IPC: H02J7/00
Filed: 2021-05-06
Abstract: A vehicle battery jump starter including a battery pack interface configured to receive at least one of a first rechargeable battery pack having a first nominal voltage and a second rechargeable battery pack having a second nominal voltage different from the first nominal voltage, a power boost module including one or more energy storage devices, and terminal clamps configured to electrically connect the vehicle battery jump starter to a vehicle battery. The jump starter further includes a controller having an electronic processor configured to close a jump start switch in response to detecting an attempted vehicle start, close a first bypass switch when the voltage of the battery pack is greater than the voltage threshold, and close the second bypass switch when the voltage of the battery pack is less than the voltage threshold.
Patent WO-2021236459-A1 (WO)
Title: Ester modified cross-linked silicone compositions
Inventor: SARKAR ALOK
IPC: C08G77/50
Filed: 2021-05-14
Abstract: The present disclosures are directed to compositions comprising a polymer having linear or branched silicone substituted by at least one alkylcarboxy group and cross-linked with an alkyl functional cross-linker, which has the benefits of compatibility and structuring of personal care components and the resultant personal care applications.
Patent WO-2021236984-A1 (WO)
Title: Predictive modeling of a manufacturing process using a set of inverted models
Inventor: BHATIA SIDHARTH
IPC: G06N3/08
Filed: 2021-05-20
Abstract: Disclosed herein is technology for performing predictive modeling to identify inputs for a manufacturing process. An example method may include receiving expected output data for a manufacturing process, wherein the expected output data defines an attribute of an output of the manufacturing process; accessing a plurality of machine learning models that model the manufacturing process; determining, using a first machine learning model, input data for the manufacturing process based on the expected output data for the manufacturing process, wherein the input data comprises a value for a first input and a value for a second input; combining the input data determined using the first machine learning model with input data determined using the second machine learning model to produce a set of inputs for the manufacturing process, wherein the set of inputs comprises candidate values for the first input and candidate values for the second input.
Patent WO-2021252648-A1 (WO)
Title: Non-operational shock mitigation for a suspension device
Inventor: EE KUEN
IPC: F16F15/00
Filed: 2021-06-09
Abstract: A flexure is described herein. The flexure includes a slider tongue with a proximal end and a distal end. The sliding tongue including a leading edge at the proximal end prone to contact an undersurface of a load beam attached to the flexure. The flexure also includes a magnetic read/write head slider attached to the slider tongue at the distal end, at least one PZT microactuator affixed to the slider tongue, between the proximal end and the distal end, and at least one dampening device at the leading edge of the slider tongue configured to reduce an impulse during a non-operational shock event and reduce stress on the at least one PZT microactuator.
Patent WO-2021252742-A1 (WO)
Title: System and method for leak prevention for domain name system requests
Inventor: BARNETT JONATHAN ALEXANDER THOROLD
IPC: H04L29/12
Filed: 2021-06-10
Abstract: Embodiments of systems and methods for DNS leak prevention and protection are disclosed herein. In particular, certain embodiments include a local DNS protection agent installed on a system and an associated trusted external DNS protection server. The DNS protection agent prevents DNS leaks from applications on the system such that all DNS requests from the system are confined to requests from the DNS protection agent to the associated DNS protection server. As the DNS leak prevention provided by the DNS protection agent stops applications on the system from circumventing the DNS protection server, all DNS requests originating from the system remain under the control of the DNS protection server and thus desired DNS protection (e.g., as implemented on the DNS protection server) may be maintained. Certain embodiments prevent applications from using certain DNS security protocols, such as DoH and DoT, without going through the DNS protection agent.
Patent WO-2022020079-A1 (WO)
Title: Method and system for acquisition of fluorescence images of live-cell biological samples
Inventor: JACKSON TIMOTHY
IPC: G06K9/00
Filed: 2021-06-30
Abstract: A method is disclosed for acquiring a single, in-focus two-dimensional projection image of a live, three-dimensional cell culture sample, with a fluorescence microscope. One or more long-exposure "Z-sweep" images are obtained, i.e. via a single or series of continuous acquisitions, while moving the Z-focal plane of a camera through the sample, to produce one or more two-dimensional images of fluorescence intensity integrated over the Z-dimension. The acquisition method is much faster than a Z-stack method, which enables higher throughput and reduces the risk of exposing the sample to too much fluorescent light. The long-exposure Z-sweep image(s) is then input into a neural network which has been trained to produce a high-quality (in-focus) two-dimensional projection image of the sample. With these high-quality projection images, biologically relevant analysis metrics can be obtained to describe the fluorescence signal using standard image analysis techniques, such as fluorescence object count and other fluorescence intensity metrics (e.g., mean intensity, texture, etc.).
Patent WO-2022032104-A1 (WO)
Title: Formulations pour particules virales hautement purifiées
Inventor: TOMKOWICZ BRIAN
IPC: C12N7/02
Filed: 2021-08-06
Abstract: L'invention concerne des formulations pour des particules virales hautement purifiées (par exemple, des particules de virus adéno-associé (AAV)). Les formulations comprennent des particules d'AAV purifiées qui sont sensiblement exemptes d'impuretés (par exemple, des impuretés liées au produit et des impuretés liées au procédé), et un ou plusieurs éléments parmi un agent tampon, un cryoprotecteur, un tensio-actif non ionique, et facultativement un sel pharmaceutiquement acceptable. Dans certains aspects, la formulation maintient ou améliore la stabilité et/ou réduit ou empêche l'agrégation des particules d'AAV purifiées.