baber/WOPTO huggingface dataset:
Patent AU-2013267872-B2 (AU)
Title: Crystallization of (20R,22R)-2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin D3 and related precursors
Inventor: DELUCA HECTOR F
IPC: C07C401/00
Filed: 2013-04-30
Granted: 2017-07-13
Abstract: Disclosed are methods of purifying the compound (20R,22R)-2-metJiylene-19- nor-22-methyl-1α,25-dihydroxyvitamin D3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving a product containing the compound in a solvent comprising hexane and 2-propanol, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals. Certain diol precursors formed during the synthesis of the compound and its diasteromers also may be obtained in crystalline form using ethyl acetate as a solvent.
Patent AU-2013286914-B2 (AU)
Title: Optimization of antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof
Inventor: LONBERG NILS
IPC: C07K16/28
Filed: 2013-07-02
Granted: 2017-06-29
Abstract: The present invention provides isolated monoclonal antibodies that specifically bind LAG-3, and have optimized functional properties compared to previously described anti-LAG-3 antibodies, such as antibody 25F7 (US 2011/0150892 A1). These properties include reduced deamidation sites, while still retaining high affinity binding to human LAG-3, and physical (i.e., thermal and chemical) stability. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided, as well as immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies. The present invention also provides methods for detecting LAG-3, as well as methods for treating stimulating immune responses using an anti-LAG-3 antibody of the invention. Combination therapy, in which the antibodies are co-administered with at least one additional immunostimulatory antibody, is also provided.
Patent AU-2013309070-B2 (AU)
Title: Belt drive system
Inventor: ADAMS RICHARD J
IPC: F16H7/02
Filed: 2013-08-27
Granted: 2015-10-01
Abstract: A pulley and drive belt system comprising a drive belt, the drive belt comprising a plurality of longitudinally spaced lugs each having an alignment groove dividing the lug into first and second lug segments, the alignment groove having an alignment groove depth, and at least one pulley configured to engage a surface of the drive belt, the at least one pulley comprising, a frame configured to rotate about a rotation axis, the frame having a circular outer rim with opposing sides, a plurality of circumferential teeth extending radially and axially of the rim, each tooth having a tooth width and each tooth being configured to be received between adjacent lugs of the drive belt, and an alignment member having a wire form and extending between adjacent circumferential teeth tops, the alignment member being configured to be received in the alignment groove, and the alignment member extending no further radially from the rotation axis than the circumferential teeth, a debris ejecting opening disposed radially inward of the alignment member between the circumferential teeth, the circumferential teeth, the alignment member and the alignment groove being configured so that with the alignment member received in the alignment groove, the drive belt rides on the circumferential teeth.
Patent AU-2013328280-B2 (AU)
Title: Ketamine derivatives
Inventor: SLEIGH JAMES WALLACE
IPC: C07C229/14
Filed: 2013-10-08
Granted: 2017-12-21
Abstract: The present invention relates to ketamine derivatives of the formula (I), pharmaceutical compositions comprising them, and methods for treating pain comprising administering them, and their use in the manufacture of medicaments for treating pain. The present invention also relates to methods for anaesthetizing and methods for sedating a subject comprising administering ketamine derivatives of the formula (II).
Patent AU-2013361736-B2 (AU)
Title: Process for the preparation of a high density polyethylene blend
Inventor: LIU YI
IPC: C08L23/06
Filed: 2013-12-17
Granted: 2016-05-19
Abstract: A high density polyethylene blend, comprising (A) 55 to 95 wt% of a high density multimodal polyethylene copolymer component having a density of at least 940 kg/m
Patent AU-2014200138-B2 (AU)
Title: Aminopyrimidines as Syk inhibitors
Inventor: ALTMAN MICHAEL D
IPC: C07D417/14
Filed: 2014-01-10
Granted: 2015-06-18
Abstract: AMINOPYRIMIDINES AS SYK INHIBITORS Abstract The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
Patent AU-2014202864-B2 (AU)
Title: Therapeutic isoxazole compounds
Inventor: KAPLAN ALAN P
IPC: A61K31/42
Filed: 2014-05-26
Granted: 2016-05-12
Abstract: H-i:\r3~,e h i Porlbl\DCC HlC\633530_ihol5/052014 The invention provides a compound of formula 1: wherein A', A , A3, R , X, Y, and B have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of monoamine oxidase B (MAO-B) enzyme function and are useful for improving cognitive function and for treating psychiatric disorders in animals.
Patent AU-2014223732-B2 (AU)
Title: Systems and methods for authenticating a user based on a biometric model associated with the user
Inventor: JAKOBSSON BJORN MARKUS
IPC: G06F21/00
Filed: 2014-02-25
Granted: 2016-06-09
Abstract: Systems and methods as provided herein may create a biometric model associated with a user. The created biometric model may be used to generate challenges that are presented to the user for authentication purposes. A user response to the challenge may be compared to an expected response, and if the user response matches within a predetermined error of the expected response, the user may be authenticated. The systems and methods may further generate challenges that are adaptively designed to address weaknesses or errors in the created model such that the model is more closely associated with a user and the user is more likely to be the only person capable of successfully responding to the generated challenges.
Patent AU-2014241420-B2 (AU)
Title: Method and device for correcting optical signals
Inventor: KINTZ GREGORY J
IPC: A61B5/1455
Filed: 2014-03-06
Granted: 2018-05-31
Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.
Patent AU-2014258969-B2 (AU)
Title: Improved pulley for high-efficiency winch
Inventor: IPPOLITO MASSIMO
IPC: B66D1/74
Filed: 2014-03-26
Granted: 2018-08-16
Abstract: An improved pulley (2) for a winch is described, in contact with at least one section of rope (1) included between an inlet section connected to a working load and an outlet section (12) connected to a resisting load, comprising a plurality of peripheral supports (3,4, 5, 6) deformable depending on a length variation of such section of rope.
Patent AU-2014317812-B2 (AU)
Title: Method of demand management and control of fluid pipe networks
Inventor: AUGHTON DAVID JOHN
IPC: G06F19/00
Filed: 2014-09-04
Granted: 2017-08-31
Abstract: The invention discloses a method of demand management and control of limited pressure head or gravity fed fluid pipe networks (42). The method includes the steps of providing a computer controlled fluid network (40) for delivery of fluid through a plurality of valves (16, 18, 20), maintaining a real time database (48) within said computer controlled fluid network (40) of predetermined parameters including flow schedules and capabilities of the plurality of valves (16, 18, 20), requesting, through a user interface (44), a flow rate and time of delivery of said fluid from the fluid network to at least one of plurality of valves (16, 18, 20), determining, using the predetermined parameters from real time database (48), the availability of providing delivery and flow rate of fluid from the fluid network (40) to the at least one of said plurality of valves (16, 18, 20) based on hydraulic capacity of the fluid network (42), and, if the hydraulic capacity is available, calculating parameters using the real time database (48) to deliver fluid to the at least one of said plurality of valves (16, 18, 20) through said computer controlled fluid network (42), whereby each of the plurality of valves (16, 18, 20) is monitored and adjustably controlled to provide the flow rate and delivery through the at least one of said plurality of valves (16, 18, 20) in unison with the monitoring and controlling of the others of the plurality of valves (16, 18, 20) to maintain the flow and manage the pressure head within fluid pipe network (42) between predetermined limits.
Patent AU-2014320014-B2 (AU)
Title: Air suction wall for equipping industrial working areas, such as welding areas
Inventor: GROHOVA MARCELA
IPC: B08B15/00
Filed: 2014-09-09
Granted: 2018-05-10
Abstract: The present invention refers in general to the field of suction systems for industrial workings like, for example, but not exclusively welding processes, and more specifically to a suction wall with properties of suction and differentiated filtration of different types of pollutant.
Patent AU-2014343342-B2 (AU)
Title: Diaphragm pump and valve device for such a pump
Inventor: FURET SEBASTIEN
IPC: F04B43/06
Filed: 2014-10-27
Granted: 2017-08-17
Abstract: A diaphragm (M) pump comprising a body (1) comprising a suction connection (2) and a discharge connection (3), a suction valve (4) and a discharge valve (5); a control chamber (6) in which the diaphragm (M) is disposed, and a working chamber (10) located on the side of the diaphragm opposite the control chamber; a control pipe (8) suitable for linking the control chamber (6) to a control connection (9) of the body, said control pipe making it possible to alternately apply a vacuum and a pressure on the diaphragm; the body (1) comprises a housing (11) oriented transversely relative to the control pipe (8), said housing being open towards the outside at one end, and closed at the other end by a bottom (13) comprising a suction opening (14) and a discharge opening (15), the diaphragm (M) being positioned close to the bottom, and being held by a cap (16) engaged in the housing, said cap having a recess forming the control chamber (6), linked to a passage (7) that opens on the lateral surface of the sleeve to establish communication with the control pipe (8), the cap (16, 16a) being held in place in the housing by a ring (17) linked with the pump body.
Patent AU-2014347599-B2 (AU)
Title: Display device and display method
Inventor: HAYASHI AKINORI
IPC: G09G3/36
Filed: 2014-11-07
Granted: 2018-01-18
Abstract: [Problem] To provide a display device and a display method allowing improvement in the display performance of a moving image. [Solution] In the present invention, a display device is provided with a display panel, and a backlight for the display panel. The display device is provided with: a control means for outputting to the backlight a control signal for controlling the illumination and extinguishing of the backlight simultaneously with the start of the updating of a frame of a display panel; and an updating means for updating the frame at predetermined periods in order to overwrite one image displayed on the screen of the display panel. The control means is configured so as to output the control signal for performing a control so as to start illumination of the backlight after the update means has started updating a given frame, and to end illumination of the backlight after the updating of the frame following the given frame has started.
Patent AU-2014369213-B2 (AU)
Title: Drug delivery systems
Inventor: SUPPER STEPHANIE
IPC: A61K9/06
Filed: 2014-12-17
Granted: 2017-10-19
Abstract: The present invention relates to thermogelling peptide delivery systems which are injected as fluid sol at ambient temperature through thin injection needles and transform into a highly viscous gel once inserted into human or animal body warm tissue. In a preferred embodiment said system is based on the use of a hydrophobic peptide, a chitosan and a glucose-phosphate.
Patent AU-2014385197-B2 (AU)
Title: Refocusable lens system with mutually-applanating internal surfaces
Inventor: MCCAFFERTY SEAN
IPC: A61F2/16
Filed: 2014-08-08
Granted: 2019-12-19
Abstract: An accommodating (re-focusable) lens system a body of which includes, upon being assembled, first and second individual lenslets having first and second optical portions sequentially disposed along an optical axis. Change in optical-power accommodation of the system is achieved by changing an applanated area of contact between the lenslets in response to force applied to the lenslets and transformed into an axial force. In specific case, the first and second lenslets form an intraocular lens (IOL) and have respective haptic portions, interlocked as a result of rotating of one lenslet with respect to another such as to bring first and second lenslets in contact at an axial point. The applanated area of contact is changed, then, in response to a radially-directed force caused by a change of distance between the interlocked ends of the haptics and transferred to the optical portions through the interlocked haptics.
Patent AU-2014385213-B2 (AU)
Title: Methods of removing a wellbore isolation device using galvanic corrosion of a metal alloy in solid solution
Inventor: FRIPP MICHAEL L
IPC: E21B29/02
Filed: 2014-12-03
Granted: 2016-12-08
Abstract: At least a portion of a wellbore isolation device consists essentially of: a metal alloy, wherein the metal alloy: (A) comprises magnesium at a concentration of at least 50% by volume of the metal alloy; and (B) at least partially dissolves in the presence of an electrolyte. A method of removing the wellbore isolation device comprises: contacting or allowing the wellbore isolation device to come in contact with an electrolyte; and allowing at least a portion of the metal alloy to dissolve.
Patent AU-2014386696-B2 (AU)
Title: Methods and systems for intraoperatively confirming location of tissue structures
Inventor: WOOD MICHAEL
IPC: A61B1/06
Filed: 2014-09-15
Granted: 2020-02-27
Abstract: Systems, methods and devices are provided for intraoperatively confirming location of tissue structures during medical procedures. Preoperative image data of a patient's skeletal structure in a vicinity of an anatomical part undergoing a medical procedure is acquired. During the procedure, after exposing tissue intraoperative image data is acquired by scanning a selected region of tissue, in a vicinity of the skeletal structure using Polarization Sensitive-Optical Coherence Tomography (PS-OCT). Regions of tissue exhibiting structural organization in the vicinity of the skeletal structure are identified from the intraoperative (PS-OCT) image data. Geometrically correlating and registering the intraoperative (PS-OCT) image data with the preoperative image data of the skeletal structure in the vicinity of the anatomical part is then performed using a priori known anatomical information about the regions of tissue exhibiting structural information.
Patent AU-2015200529-B2 (AU)
Title: Track support of an electric power system at ground level for land vehicles, rail comprising such a track support and method of installation
Inventor: DUPRAT PATRICK
IPC: E01B21/00
Filed: 2015-02-04
Granted: 2019-08-22
Abstract: Track support of an electric power system at ground level for land vehicles, rail comprising such a track support and method of installation This support (36), as a profile in an electrically insulating material, comprises a substantially planar upper surface (50), provided with a longitudinal flute (60) intended for receiving a track segment, and a longitudinal groove (70) intended for receiving a low voltage electric power supply cable; and a lower surface (52) intended to bear upon a base for maintaining the support in the roadway. It is characterized in that the lower surface (52) is curved, preferably V-shaped, so that the support is concave so as to be at least transversely maintained in a recess with a mating shape, made in the base. Fig. 5 - __ - _ _ -1/7 rJ r4-. NJn
Patent AU-2015202007-B2 (AU)
Title: B-cell antigen presenting cell assay
Inventor: SINDHI RAKESH
IPC: G01N33/68
Filed: 2015-04-21
Granted: 2016-09-01
Abstract: Disclosed herein are methods for diagnosing or predicting B-cell rejection in a subject. In one example, for assessing transplant rejection, the method includes determining an antigen presenting index by comparing uptake of a donor antigen to uptake of a reference antigen in a biological sample obtained from the subject. In another example, for assessing GVHD, the method includes determining an antigen presenting index by comparing uptake of a recipient antigen to uptake of a reference antigen in a biological sample obtained from the subject.
Patent AU-2015203267-B2 (AU)
Title: Tile or masonary saw assembly with double movement
Inventor: ELMESTRAND KARL
IPC: B23D47/02
Filed: 2015-06-16
Granted: 2017-02-23
Abstract: TILE OR MASONARY SAW ASSEMBLY WITH DOUBLE MOVEMENT A tile or masonry saw assembly (100/200) may include a saw (110/210), a frame (120/220), and a workpiece support (126). The saw (110/210) includes a motor (112/212) operable to turn a blade assembly (114/214) to cut a workpiece. The frame (120/220) is operably coupled to the saw (110/210) to enable the saw (110/210) to be moved along the frame (120/220) in a first direction. The workpiece support (126) is operably coupled to the frame (120/220) to support the workpiece relative to the saw (110/210), and to allow the workpiece support (126) to be moved along the frame (120/220). The saw assembly (100/200) further includes a movement assembly (300) via which both movement of the workpiece support (126) and movement of the saw (110/210) relative to the frame (120/220) is accomplished, such that a movement of the work piece support (126) along the frame (120/220) in a second direction is enabled to cause the saw (110/220) to move along the frame (120/220) in the first direction which is opposite the second direction. C) o CN oc
Patent AU-2015215042-B2 (AU)
Title: Production of cider with Pichia kluyveri yeast
Inventor: SAERENS SOFIE
IPC: C12G3/02
Filed: 2015-02-04
Granted: 2018-12-06
Abstract: The present invention relates to the field of production of a beverage, especially cider, by fermentation of apple juice and/or pear juice. Specifically, the invention relates to a method of preparing a beverage with enhanced levels of desirable fermentation-derived flavor compounds comprising a step of fermentation of apple juice and/or pear juice with at least one Pichia kluyveri yeast strain, a beverage obtainable by the method and a cider comprising a high concentration of the flavor compound, hexyl acetate.
Patent AU-2015215750-B2 (AU)
Title: Nucleic acid detection or quantification method using mask oligonucleotide, and device for same
Inventor: SUGIMOTO NORIHIKO
IPC: C12N15/09
Filed: 2015-01-29
Granted: 2021-02-25
Abstract: Through the present invention, a mask oligonucleotide is hybridized in regions on either side of a region in which an oligonucleotide probe is hybridized in a single-stranded region of a nucleic acid to be assayed, the region in which the probe is hybridized is thereby opened and the single-stranded region of the target nucleic acid is maintained in a stable state. By then subjecting the nucleic acid having such a single-stranded region to nucleic acid chromatography, the desired target nucleic acid is detected and quantified with high sensitivity by an extremely simple process.
Patent AU-2015224522-B2 (AU)
Title: Drug component admixture library for a drug infusion delivery system
Inventor: CHOSSAT OLIVIER
IPC: G01D1/18
Filed: 2015-09-11
Granted: 2017-06-22
Abstract: Minimizing improper dosage of a drug admixture (including a single primary drug component and at least one second drug component). For each drug component in the drug admixture, receiving a name of the drug component along with its dosage unit, a maximum dose warning level and a maximum concentration warning level. Receiving a concentration for each of the single primary drug component and the at least one secondary drug component; and a dose setting of only the primary drug component. Automatically calculating a dose of each of the at least one secondary drug component. Generating an alert when: (i) the received dose setting of the primary drug component or calculated dose setting of the at least one secondary drug component exceeds the dose warning level; or (ii) the received concentration of the primary drug component or the at least one secondary drug component exceeds the concentration warning level.
Patent AU-2015228775-B2 (AU)
Title: Topical compositions comprising extract of Coriolus versicolor for autoimmunity enhancement
Inventor: LOSA DOMINGUEZ FERNANDO
IPC: A61K36/58
Filed: 2015-03-13
Granted: 2020-04-02
Abstract: The present invention provides a topical composition comprising extract from
Patent AU-2015249934-B2 (AU)
Title: Condensate-gas ratios of hydrocarbon-containing fluids
Inventor: KRIEL WAYNE A
IPC: G01N33/28
Filed: 2015-04-21
Granted: 2019-04-04
Abstract: Analyzing a hydrocarbon-containing fluid, as provided from a hydrocarbon producing well, includes providing a hydrocarbon- containing fluid to a separation system (100) including a cyclone separator (102), and separating the hydrocarbon-containing fluid into a gas phase sample and a liquid phase sample. The liquid phase sample is separated into an aqueous sample, water rich sample, and a non-aqueous sample, such as condensate or oil rich sample. The volume of the gas phase sample and of the non-aqueous sample are assessed, and the ratio of the volume of the non-aqueous sample to the volume of the gas phase sample yields the condensate-gas ratio.
Patent AU-2015256012-B2 (AU)
Title: VMAT2 inhibitors for the treatment of hyperkinetic movement disorders
Inventor: O'BRIEN CHRISTOPHER F
IPC: A61P43/00
Filed: 2015-05-06
Granted: 2020-07-23
Abstract: Methods for treating hyperkinetic diseases and disorders, such as tardive dyskinesia, are provided. In a certain embodiment, the potent VMAT2 inhibitor (+)α-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol ((+)α-HTBZ) is used in the methods described herein for treating a subject in need thereof.
Patent AU-2015276149-B2 (AU)
Title: Composition for preventing or treating dental erosion
Inventor: BERGLUND THOMAS
IPC: A61Q11/00
Filed: 2015-06-18
Granted: 2020-08-20
Abstract: The present invention relates to a composition of pH in the range 2.0 to 4.5 comprising at least one fluoride source and at least one other agent for use in prevention and/or treatment of dental erosion.
Patent AU-2015339284-B2 (AU)
Title: Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
Inventor: BAILEY ANTOINETTE
IPC: A61K35/741
Filed: 2015-10-28
Granted: 2021-08-05
Abstract: Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in need thereof. The subject in need thereof can have a gut micro biota signature characteristic of an adult. The bacterial species can include