baber/WOPTO huggingface dataset:
Patent JP-2002503202-A (JP)
IPC: C07D271/08
Filed: 1997-01-31
Abstract: The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
Patent JP-H11509689-A (JP)
Title: Ｐｔｃ  素子を含む表面実装可能な電気装置
IPC: H01C7/02
Filed: 1997-01-21
Abstract: (57)【要約】
抵抗素子（20）と、抵抗素子（20）の頂面（30）と電気的に接触する第１電極(100)及び抵抗素子（20）の底面（40）と電気的に接触する第２電極(110)から成る電気装置（10）。第１及び第２電極（100，110）上に絶縁層(120)を形成する。第１及び第２電極（100，110）から絶縁層(120)の一部を除去することによって、第１及び第２接触点（130，140）を形成する。絶縁層(120)上に導電層(150)を形成して、接触点（130，140）において第１及び第２電極（100，110）と電気的に接触させる。導電層(150)の一部を除去することにより、非導電ギャップ（160，170）によって分離された第１及び第２終端部（155，156）を形成する。この装置（10）の包み込み（wrap−around）構成は、電気装置（10）の同じ側から両電極（100，110）に対して電気的接続をすることが可能になる。
Patent JP-H11502214-A (JP)
Title: イチョウの葉の乾操抽出物を含有する発泡性組成物
IPC: A61K9/00
Filed: 1996-03-15
Abstract: (57)【要約】
本発明は、イチョウの葉の乾燥抽出物および発泡性混合物とを含有する発泡性組成物に関する。その混合物を水に溶解することによって、使用期間中安定な実質的に濁りが無いほぼ中性の溶液が得られる。
Patent JP-2000505699-A (JP)
Title: 臭気制御を提供し、局所的接着剤を用いて着用者の皮膚に取り着けるための使い捨て吸収製品
IPC: A41B9/12
Filed: 1997-12-22
Abstract: (57)【要約】
本発明は使い捨て吸収製品、特に衛生ナプキン、パンティライナー、成人用失禁製品又は汗パッドに関する。特に、本発明は、体液の吸収が所望される領域において着用者の皮膚に直接取り着けることにより着用され、臭気制御システムを備えるこの種の使い捨て吸収製品に関する。
Patent JP-H10500153-A (JP)
Title: エネルギー重合性組成物、オキサゾリンのホモポリマー及びコポリマー
IPC: C08G73/06
Filed: 1995-04-28
Abstract: (57)【要約】
1,3-オキサゾリン及び1,3-オキサジンモノマーもしくは化合物を含む少なくとも１種のカチオン硬化性５もしくは６員環1,3-オキサジル複素環式化合物及び有機金属化合物を含む触媒有効量の開始剤を含むエネルギー重合性組成物。このオキサゾリンホモポリマー及びコオリマーは高い反応速度、改良された熱安定性、及び高いガラス転移温度を示す。得られる接着剤組成物は電子用用途、例えばポリイミドシートもしくはフィルム、可撓性回路もしくは光ファイバーコネクターへの接着に特に適している。
Patent JP-H10500482-A (JP)
Title: ２端部を有する同調フオーク部材の力変換器の新しい疑似モードマツプ
IPC: H03H9/21
Filed: 1995-05-03
Abstract: (57)【要約】
２端部を有する同調フオーク部材（DETF）が各端部で共に接合される２個の振動ビーム部材から構成され、各ビーム部材は厚さがｔ、幅がｗ、長さがｍであり、DETFは長さがＬであり、DETFの寸法比t／wおよびL／mは、特定の寸法比t／wおよびL／mでの有限要素分析法の詳細な計算に基づく比較的より正確な疑似モードマツプにより選定される。これにより有限要素分析法の結果は関連する寸法範囲全体に亘る多項式最小二乗法と一致する。疑似モードマツプに対する有限要素分析法の結果は単純ビーム部材理論に基づく疑似モードマツプに対し最大14％の差を与える。更に本発明による疑似モードマツプは、DETFの機械的なＱ値を増加させるDETFの基本領域内での対称アウトリガの採用を参酌している。
Patent JP-2000507381-A (JP)
Title: Ｐｒｍｌ記録チャネル用率２４／２５変調コード
IPC: H03M5/14
Filed: 1997-12-31
Abstract: (57)【要約】
率２４／２５変調エンコード方法および装置はＰＲＭＬ磁気記録チャネルにおける効率を向上させる。率２４／２５コードワードは合理的なグローバルランレングス制約で改良されたコード率を達成するため、インタリーブされたエンコードされていないバイトと組合されるユーザデータの１バイトの率８／９ＲＬＬエンコーディングを使用する。率８／９ＲＬＬ（０，３）サブコードを使用すると、率２４／２５ＲＬＬ（０，１１）コードができ、一方、率８／９（０，６／５）サブコードでは率２４／２５ＲＬＬ（０，１４／１３）コードとなる。
Patent JP-2000510074-A (JP)
Title: 自動車ドアモジュール
IPC: B60J1/17
Filed: 1998-01-23
Abstract: (57)【要約】
自動車ドア（１０）の最内側パネル（１２）の開口（１４）に取り付けるためのモジュール（１６）であって、該モジュールは、中心部（２０）と該中心部から夫々異なる方向に延びる少なくとも２つのアーム（２２）とを持つ構造部材（１８）であって、各々のアームは前記最内側パネルに取り付けられたとき該アーム又は少なくとも２つのアームが前記開口に亘って延在するように前記最内側パネルに固定可能な自由端部（２６）を有する前記構造部材（１８）と、前記構造部材に固定された支持パネル（２８）と、前記支持パネルに取り付けられた少なくとも１つのドア部品（３４〜４０）と、を含む。ドア部品のより容易な組み立て及びより軽量な構成が達成できる。
Patent JP-2001512377-A (JP)
Title: 電動式の手持ち機械鋸
IPC: B23D49/16
Filed: 1998-10-22
Abstract: (57)【要約】
電動式の手持ち機械鋸、殊に精密切断鋸であって、機械ケーシング（１０）、交換可能な鋸身（１２）及び、該鋸身（１２）を駆動して往復振動の鋸挽き運動させる駆動部（１１）を備えている形式のものにおいて、鋸身駆動部（１１）の構造を著しく簡単にするために、鋸身（１２）が、機械ケーシング（１０）に交換可能に装着された案内（４４）内に長手方向移動可能に受容されていて、直接に駆動部（１１）によって駆動されて、案内（４４）内で振動運動させられるようになっている。
Patent JP-2000506939-A (JP)
Title: 湾曲焼入れ断面材要素の製造方法およびこの方法を実施するためのダイ工具
IPC: B21D7/16
Filed: 1997-03-04
Abstract: (57)【要約】
本発明は、閉じた断面材要素、梁、又は、これらの類似物から、断面材要素を湾曲させることができるダイ工具（５）を使用して、湾曲焼入れ断面材要素を製造する方法に関連し、焼入れ温度まで加熱された断面材要素（２）を、ダイ工具内に押し出して、ダイ工具によって提供された形態に湾曲させ、その後、流水装置またはシャワー装置によって、冷却液で冷却し、冷却液は、湾曲断面材要素を収容したダイ工具（５）に供給されるものであり、冷却液は、ダイ工具（５）の中を通り、これにより、入れられた断面材要素の外側を通る。本発明を実施するために、幾つかの工具半部（９、９’）を備えたダイ工具が使用され、これらの工具半部は、協働してダイ工具（５）内に配置された断面材要素を湾曲させ、工具半部の間で工具半部を押し、工具半部（９、９’）の各々は、内側に、対向する交互になった円周リブ（１３）および溝（１４）を備えており、これらは、工具半部の内側に沿って連続的に延びており、冷却液をダイ工具を通して送り、ダイ工具（５）に入れられた断面材要素（２）の外側から熱を放散させる。
Patent JP-2001508923-A (JP)
Title: 容量結合ｒｆプラズマ反応室
IPC: H05H1/46
Filed: 1998-01-13
Abstract: (57)【要約】
容量結合ＲＦプラズマ反応室において、１対の隔てられた電極（１０、２０）の間に放電領域（３）が設けられ、これらの電極のうちの少なくとも一方（１０）は多数の副電極（１２）に細分され、これらはグループ（Ａ、Ｂ、Ｃ）においてそれぞれ対応の電気信号で動作させられる。これらの信号（Ｖ 11 からＶ 13 ）の振幅、位相同期およびスペクトル内容を適当に選択することにより、特に大面積のワークピースを処理する際に、第２の電極（２０）上に置かれるワークピースに対して所望の分布の処理効果が実現できる。
Patent JP-H11510654-A (JP)
Title: 音声表題用装置及び方法
IPC: H04N5/78
Filed: 1996-04-26
Abstract: (57)【要約】
記録されたプログラムに対して音声表題を供給する装置は、オーディオ記録部分（２４２）及び制御記録部分（２４６）を有している順次記録媒体上に記録するレコーダ（１１，１９）を含む。制御入力（２２２）は、音声表題の開始を示すために設けられかつ開始インディケータ（２５２）は、順次媒体の制御記録部分に記録される。マイクロホン（２６４）または他の装置は、音声表題を入力しかつ制御記録部分の音声表題の開始の記録された表示に続いて、順次、順次媒体のオーディオ記録部分に入力された音声表題を記録するために設けられている。制御入力（２２２）は、音声表題の終了を示すために設けられかつ終了インディケータ（２５４）は、オーディオ記録部分の記録された音声表題に続いて、順次、順次媒体の制御記録部分に記録される。装置は、入力された音声表題をディジタル化するためのアナログ／ディレクトリ変換器（２７０）及びディジタル化された音声表題を記憶するためのメモリ（３３）を含む。装置の別の態様は、記憶されたディジタル化された音声表題から音声を合成するための音声シンセサイザ（２６０）を含む。
Patent JP-2000507439-A (JP)
IPC: H01L41/083
Filed: 1997-03-26
Abstract: This invention relates to an actuator or motor comprising an electromechanical material which alters its shape under the influence of an electrical voltage. Said actuator comprises at least a monolitic module (1,2) with electrodes integrated in said electromechanical material and in that the force or displacement due to the applied voltages is transferred, to the point to be actuated or moved by the shape change of the material, using at least two independent contact points. The invention also relates to a method for fabricating said actuator or motor.
Patent JP-2001513231-A (JP)
Title: マルチアプリケーションｉｃカードシステム
IPC: G06F21/10
Filed: 1998-02-19
Abstract: (57)【要約】
アプリケーションを選択的にロードおよび削除する能力を有するマルチアプリケーションＩＣカードシステムが開示される。ＩＣカードにアプリケーションをロードする前に、テストが行われ、カードに記憶された個人登録データを用い、且つ、その個人登録データと、アプリケーションがロードされ得るカードの１つ以上の組を示す、アプリケーションに関連する許可データと、を比較して、カードが、アプリケーションを受け取るのに適しているかどうかを判定する。カードの個人登録データが、そのアプリケーションについての許可の許容可能な組の中にあれば、カードにアプリケーションがロードされ得る。好ましくは、個人登録データは、カード番号、発行者、製品分類、カードが個人登録された日付、を表すデータを含む。
Patent JP-2002504890-A (JP)
IPC: A23L3/3481
Filed: 1997-04-17
Abstract: The invention relates to a composition for decontaminating raw materials, products, water and/or production means, which composition is prepared from at least hydrogen peroxide, glycerol and glycol acid, a method for the preparation thereof, comprising mixing a solution of glycerol and a solution of glycol acid, and dropwise adding the mixture obtained to a solution of hydrogen peroxide under such conditions that the solution of hydrogen peroxide maintains a temperature of 7 DEG C and preferably below 4 DEG C. Further, the invention relates to a method for decontaminating objects.
Patent JP-2000511565-A (JP)
IPC: A61K38/22
Filed: 1998-03-20
Abstract: The subject of the present invention are variants of ciliary neurotrophic factor with enhanced receptor selectivity (CNTFR), useful for the treatment of diseases and disorders including motor neuron diseases and muscle degenerative diseases. Another subject of the invention is to provide a method for identifying the above mentioned CNTF variants. The hCNTF variants with the amino acid substitutions in accordance with the present invention, have a reduced ability, as compared to the human CNTF, to elicit biological effects through soluble CNTFR, without affecting its ability to activate membrane-bound neuronal CNTF receptors, thereby improving its therapeutic properties. FIG. 1 shows the reduced CNTFR binding affinity of a CNTF variant according to the invention (IA-CNTF; SEQ ID NO: 2). It is evident that the binding affinity of this variant to the CNTFR is reduced as compared to the wild-type human CNTF molecule.
Patent JP-2000503108-A (JP)
Title: 液化天然ガスの保存・輸送方法および装置
IPC: F25J1/02
Filed: 1998-03-19
Abstract: (57)【要約】
主に窒素およびメタンからなる液化天然ガス（ＬＮＧ）を、ＬＮＧデコクションをタンク２内に保存し、保存したまま輸送する方法である。デコクションをタンク２から取出し、デコクションの圧力を高くした後、デコクションをメタンおよび窒素の凝縮温度の間にある温度まで冷却器２０において冷却しする。凝縮されたメタンのみをタンク２に戻す。また、この方法の実施装置でもある。
Patent MD-20010296-A (MD)
Title: Process for billet obtaining from the round large-section ingots and rotatable follow-rest for realization thereof
Inventor: MATVEENCO DUMITRU
IPC: B23Q1/76
Filed: 2001-07-18
Abstract: The invention relates to the metal working in small-scale production conditions, in particular to the billet obtaining operations for further turning operations. The process consists in cutting by turning of the billets from the ingot by means of a rotatable follow-rest for large-section ingots.The rotatable follow-rest, according to the invention, contains a base plate, provided with a fixing fork, a collapsible frame, wherein there are mounted two bearing rests, supporting a pipe, the extremities of which are provided with two ingot fixing devices.The result consists in reducing the labour input, in increasing the precision and in decreasing the billet working time.Claims: 3Fig.: 3
Patent MX-157411-A (MX)
Inventor: KRYSCYK ROBERT
IPC: F16D3/04
Filed: 1983-01-11
Abstract: A drive arrangement is disclosed which provides for the transfer of torque between two non-aligned shafts. The drive arrangement includes an intermediate shaft having outwardly projecting claws secured to each end thereof which are engageable in a positive driving manner with corresponding claws formed on the first and second shafts, respectively. A pair of resilient members are interposed between the claws at each end of the intermediate shaft which provide flexible couplings for facilitating the transfer of torque therebetween. Such a drive arrangement corrects for pure eccentricity between the parallel axes of the first and second shafts as well as correcting for any lack of parallelism between these axes.
Patent MX-157706-A (MX)
Inventor: DEAN MARK EDWARD
IPC: G06F11/07
Filed: 1984-11-12
Abstract: In a data processing system including a main processor (1) and a co-processor (2), a logic circuit (6) is coupled to receive error and busy outputs of the co-processor to generate an interrupt output on co-incidence of active error and busy signals and to latch the busy signal to the main processor to ensure that the main processor will honour the interrupt before executing another co-processor instruction.
Patent NZ-203112-A (NZ)
Title: Double walled,insulated,metal flue pipe
Inventor: VAN HATTEM H W M
IPC: E04F17/02
Filed: 1983-01-28
Abstract: Heat-insulating pipe element of a pipe for conveying flue gases comprising a metal outer tube, a metal inner tube fitted co-axially in the outer tube by fixing means in a substantially immovable relation to the outer tube and a heat-insulating material being provided in the space between the tubes, whereby the fixing means comprises at least one elongate connecting element which is provided in longitudinal direction between the tubes and of which the extremities are connected with the respective end parts of the outer tube of which the central part is connected with the central part of the inner tube, and whereby the fixing means also comprises the insulating material, in the form of a continuous insulating layer, having a coherent, fibrous resilient structure.
Patent NZ-220915-A (NZ)
Title: Odometric compacting of anode blocks: relaxing lateral stress after compaction
Inventor: COSTE B
IPC: B30B11/02
Filed: 1987-07-01
Abstract: The invention relates to a process for relaxing lateral stresses at the end of shaping by compacting of a block constituted by an aggregate and a binder (such as a carbon-containing paste), to which is applied a main monoaxial stress in a rigid mold having a bottom and four side walls. According to the process, at the end of compacting and along the compacting axis, there is maintained a residual stress of between 50 and 2000 kilopascals, and preferably between 100 and 500 kilopascals. At least two of the side walls of the mold are then moved apart by a few millimeters, followed by the elimination of the main stress and the extraction of the molded block. The residual stress is maintained for a period of between 1 and 20 seconds following the moving apart of the walls.
Patent NZ-227562-A (NZ)
Title: Recombinant vaccinia virus (mva) containing a dna insert coding for a foreign antigen
Inventor: ALTENBURGER WERNER
IPC: C12N15/39
Filed: 1989-01-06
Abstract: The recombinant vaccinia viruses are derived from modified virus Ankara (MVA) and contain a DNA sequence which codes for a foreign antigen. The invention also relates to vaccines which contain a virus of this type in a form suitable for injection, and to processes for the preparation thereof. The invention furthermore relates to the use of a recombinant vaccinia virus MVA for the preparation of a heterologous protein in eukaryotic cells.
Patent NZ-233451-A (NZ)
Title: Production of vascular endothelial growth factor and dna encoding same
Inventor: FERRARA NAPOLEONE
IPC: C12N15/16
Filed: 1990-04-26
Abstract: DNA isolates coding for a vascular endothelial cell growth factor may be used to produce the protein via recombinant expression systems. Such protein is useful therapeutically to treat conditions in which a selective action on the vascular endothelial cells, in the absence of excessive connective tissue proliferation, is desirable.
Patent NZ-235320-A (NZ)
Title: Fruit machine: win by character substitution adjusts payout.
Inventor: NAGAO YUJI
IPC: A63F5/04
Filed: 1990-09-14
Abstract: This invention relates a game machine in which a combination of characters stopped along a winning line is judged based on a winning table showing winning combinations of characters to determine the presence of a win and a payment of coins. In this game machine, a substitutable character can be used as another character, and when its substitution makes a combination of characters a winning combination, a payment of coins for the combination is increased or decreased to determine a new payment of coins.
Patent NZ-237070-A (NZ)
Title: Odour-control composition comprising carbon black, white particles, and a
Inventor: KARAPASHA NANCY
IPC: A61F13/49
Filed: 1991-02-11
Abstract: Compositions comprise carbon particles combined with white odor-controlling agents by means of binders. The preferred particle form of the compositions is substantially lighter in color than the original carbon, and the resulting particles are preferred for use in the manufacture of catamenials, diapers, bandages, and the like. Particles comprising carbon and zeolites are not only desirably lighter in color, but also control a broad spectrum of malodors associated with body fluids.
Patent NZ-243175-A (NZ)
Title: Use of rapamycin to prepare medicaments for the treatment of adult t-cell leukemia/lymphoma
Inventor: MILLER GLENN ALVIN
IPC: A61K31/435
Filed: 1992-06-17
Abstract: This invention provides a method of treating adult T-cell leukemia/lymphoma (ATL) in a mammal in need thereof which comprises administering an antiproliferative amount of rapamycin, and is particularly useful in arresting the progression of or inducing remission of ATL.
Patent NZ-244442-A (NZ)
Title: Benzazapine carboxyalkyl derivatives, and pharmaceutical compositions thereof
Inventor: WARSHAWSKY ALAN M
IPC: C07D498/04
Filed: 1992-09-22
Abstract: The present invention relates to compounds of the formula <CHEM>  wherein   B<5> and B<6>   are each independently hydrogen; hydroxy; -OR<6> wherein R<6> is a C<5>-C<8> alkyl or an Ar-Y group wherein Ar is aryl and Y is a hydrogen or C<5>-C<8> alkyl; or, where B<5> and B<6> are attached to adjacent carbon atoms, B<5> and B<6> can be taken together with said adjacent carbons to form a benzene ring or methylenedioxy; A   is a bond, methylene or oxygen, sulfur or NR<8> or NCOR psi wherein R<8> is hydrogen, a C<5>-C<8> alkyl or an Ar-Y- group and R psi  is -CF<7>, a C<5>-C<5><4> alkyl or an Ar-Y- group; R<7>   is hydrogen or -CH<6>OC(O)C(CH<7>)<7>; R<5>   is hydrogen, C<5>-C<8> alkyl or -CH<6>OC(O)-C(CH<7>)<7>; and n   is an integer 1 to 3, which are useful as inhibitors of enkephalinase and ACE.
Patent NZ-244644-A (NZ)
Title: Cyclic vasoactive intestinal peptide analogues and compositions thereof
Inventor: BOLIN DAVID ROBERT
IPC: A61K38/08
Filed: 1992-10-07
Abstract: The present invention relates to vasoactive peptide (VIP) analogs wherein the side chain carboxy terminus of one amino acid in the peptide chain is attached covalently to the side chain amino terminus of another amino acid in the peptide chain via the formation of an amide bond. The covalent bonding between the two amino acid residues in the peptide chain yields a ring structure. The present invention provides cyclic vasoactive peptides and pharmaceutical compositions comprising such a cyclic vasoactive peptide for the treatment of bronchotracheal constrictive disorders.
Patent NZ-256118-A (NZ)
Title: Infusion bag with two compartments and pull thread to contract the bag
Inventor: VAN DER ZON PETRUS WILHELMUS M
IPC: B65D85/808
Filed: 1993-10-01
Abstract: A dual compartment infusion packet has the compartments directly secured to each other at one end of the packet and separated by a V-fold of the packet material at the other end. A suspension thread has an intermediate portion lying within the fold and end portions extending therefrom through attachment means at the other end of the packet. The end portions are displaceable in the attachment means so that when tensioned they contract the packet to squeeze out liquid held in the packet after an infusion process.
Patent NZ-270804-A (NZ)
Title: Multiple layer absorbent core comprising a nonwoven acquisition/distribution layer including pet fibres and a storage layer including absorbent gelling material
Inventor: NOEL JOHN RICHARD
IPC: A61F/
Filed: 1992-01-06
Abstract: An absorbent article, such as a disposable diaper, adult incontinent pad, sanitary napkin, and the like, is disclosed which has a rapid acquiring, multiple layer absorbent core. The absorbent article may be in an improved shape that can be worn in the wearer's usual undergarments. The absorbent article of the present invention comprises a liquid pervious topsheet, a liquid impervious backsheet, and a multiple layer absorbent core positioned between the topsheet and the backsheet. The multiple layer absorbent core comprises at least one rapid acquiring acquisition/distribution layer and at least one storage layer positioned subjacent each acquisition layer. The acquisition/distribution layers have a fluid acquisition/distribution rate of at least about 2 cubic centimeters of synthetic urine per second when tested under a pressure of about 28 grams per square centimeter. The storage layers at least partially comprise a "high-speed" absorbent gelling material which is capable of reaching at least about 40% of its absorptive capacity in less than or equal to about 10 seconds. A multiple layer absorbent core for an absorbent article is also disclosed.
Patent NZ-276039-A (NZ)
Title: Manure/urine catcher; harnessed pouch worn by a horse catches manure and urine
Inventor: MCNAMARA WILLIAM JOHN
IPC: A01K23/00
Filed: 1994-11-17
Abstract: PCT No. PCT/AU94/00709 Sec. 371 Date May 20, 1996 Sec. 102(e) Date May 20, 1996 PCT Filed Nov. 17, 1994 PCT Pub. No. WO95/13695 PCT Pub. Date May 26, 1995A manure and urine collector pouch for, and to be worn by, an entire or gelded/spayed male/female horse or other animal of the equidae family, the pouch providing a forwardly-extending trough (23) for receiving relatively fluent matter, such that the total weight of the system and contents is distributed along a substantial part of the body.
Patent NZ-281059-A (NZ)
Title: Solvent-depleted avermectin/zein composition; antiparasitic uses
Inventor: DEMCHAK RICHARD J
IPC: A61P33/10
Filed: 1995-01-30
Abstract: Their is disclosed a novel solvent-depletion process for making an avermectin/zein composition and the composition itself, which has excellent photostability and unexpected bioavailability to foliar-feeding insects. The process consists of depleting a dilute acidic, basic or alcoholic solvent from an emulsified solution of avermectin, zein, and dilute solvent.
Patent NZ-303672-A (NZ)
Title: Male contraceptive comprising anti-oestrogens
Inventor: HABENICHT URSULA FRIEDERIKE
IPC: A61P13/02
Filed: 1997-09-16
Abstract: The use of anti-oestrogens (aromatase inhibitors, oestrogen receptor antagonists) to prepare male contraceptive medicaments and a method of controlling male fertility using said medicaments.
Patent NZ-323003-A (NZ)
Title: Alkynyl and ether or amino (-O- or -NR10-) containing aryl derivatives
Inventor: ARVAI GEZA
IPC: C07C43/166
Filed: 1996-11-19
Abstract: he application relates to compounds of general formula (1): Ar-(CR1R2)m-(YR3R4)n-X-(CR5R6)o-CR7R8)p-C=C-E their optically active isomers and salts wherein Ar = alycyclic, aromatic or one or more heteroatom containing heterocyclic moiety, optionally substituted by one or more alkoxy-, methylenedioxy-, alkyl-, halogen-, haloalkyl-, or nitro-group and/or condensed with a benzene ring; R1, R2 = independently H, alkyl, alkenyl, haloalkyl, phenyl, substituted phenyl, cycloalkyl, R3, R4 = independently H, alkyl, alkenyl, haloalkyl, phenyl, substituted phenyl, cycloalkyl, or R3, R4 are together =O, Y = C; PO, or YR3R4 together (a) group; X = -O-; -NR10-, R9 = H, alkyl, phenyl, substituted phenyl; R10 = H, alkyl; R5, R6, R7, R8 are independently H, alkyl, alkenyl, haloalkyl, or Ar-(CR1R2)m-(YR3R4)n-X- form together a carboximide group; E = H, halogen, methyl; m = 0, 1, 2; n = 0, 1; o = 0, 1, 2; p = 0, 1, 2, with the proviso, that the sum of the atoms or groups of the -(CR1R2)m-(CR3R4)n-X-(CR5R6)o-(CR7R8)p bridge skeleton is 3 and the -CC-E skeleton forms with the atoms of the bridge a linear chain, consisting of 6 atoms ending preferably in a methyl group, furthermore with the proviso, that if Ar stands for a naphthyl group, Y means C-atom, X means O-atom, R3 and R4 together cannot mean =O.  The compounds of general formula (1) can be applied as active ingredients of pesticide, preferably arthropodicide compositions, and as synergists of other arthropodicide active ingredients.
Patent NZ-329594-A (NZ)
Title: Use of chemotactic tripeptide compounds for treating sites of infection and inflammation
Inventor: FISCHMAN ALAN J
IPC: A61K38/00
Filed: 1994-10-24
Abstract: A chemotactic peptide is used in the manufacture of a medicament for treating a site of inflammation or infection. The chemotactic has the formula X-Y-Leu-Phe-[Z]n-[T]a wherein X is an amino protecting group of formula -C(=R4)-R3 other than N-formyl or t-BOC; R3 is H, alkyl, alkynyl, alkenyl, alkoxy, aralkoxy or amino; R4 is O or S; Y is amino acid residue; Z is a spacer selected from aliphatic diamines, R6 or mixtures thereof; R6 is one or more amino acid residues which can be the same or different; n is 0 or 1; T is a therapeutic agent or a diagnostically detectable label and a is 0 or 1.
Patent NZ-332645-A (NZ)
Title: use of a bis-indolylmaleimide derivative for treating VEGF related diseases
Inventor: JIROUSEK MICHAEL R
IPC: A61K31/706
Filed: 1997-05-01
Abstract: An inhibitor of the b-isozyme of protein kinase C is used in the manufacture of a medicament for treating neoplasia, rheumatoid arthritis or keloid or for inhibiting VEGF stimulated capillary permeability associated with pulmonary edema. The preferred inhibitor is a bis-indolylmaleimide or a macrocyclic bis-indolylmaleimide. The bis-indolylmaleimide can have the formula I wherein W is O, S(O)q, CO, optionally substituted alkylene, alkenylene, aryl, aryl-(CH2)m-O-, fused bicyclic, fused bicyclic-(CH2)m-O-, heterocycle, heterocycle-(CH2)m-O-, NR3, NOR3, CONH or NHCO; X and Y are independently optionally substituted alkylene or together X, Y and W combine to form -(CH2)n-AA-; each R1 is H or up to four of halo, alkyl, hydroxy, alkoxy, haloalkyl, nitro, NR4R5 or NHCO-alkyl; R2 is H, CH3CO, NH2 or OH; n is 2 to 5; q is 0 to 2 and m is 0 to 3; AA is an amino residue and R3, R4 and R5 are as defined in the specification.