baber/WOPTO huggingface dataset:
Patent PH-12019500603-A1 (PH)
Title: Anti-steap2 antibodies, antibody-drug conjugates, and bispecific antigen-binding molecules that bind steap2 and cd3, and uses thereof
Inventor: RUDGE JOHN
IPC: C07K16/30
Filed: 2019-03-19
Abstract: The protein known as six-transmembrane epithelial antigen of prostate 2 (STEAP2) is highly expressed in prostate cancer and is associated with the expression of other prostate cancer-associated genes. The present invention provides novel full-length human IgG antibodies that bind to human STEAP2 (monospecific antibodies). The present invention also provides novel bispecific antibodies (bsAbs) that bind to both STEAP2 and CD3 and activate T cells via the CD3 complex in the presence of STEAP2 -expressing tumors. According to certain embodiments, the present invention provides bispecific antigen-binding molecules comprising a first antigen-binding domain that specifically binds human and monkey CD3, and a second antigen-binding molecule that specifically binds humanSTEAP2. In certain embodiments, the bispecific antigen-binding molecules of the present invention are capable of inhibiting the growth of tumors expressing STEAP2. The bispecific antigen-binding molecules of the invention are useful for the treatment of prostate diseases and disorders in which an upregulated or induced STEAP2 -targeted immune response is desired and/or therapeutically beneficial. For example, the bispecific antibodies of the invention are useful for the treatment of prostate cancers, including castrate-resistant prostate cancer. The present invention also includes anti-STEAP2 antibody drug conjugates which inhibit tumor growth in vivo.
Patent PH-12019550261-A1 (PH)
Title: Compositions and methods for internalizing enzymes
Inventor: BAIK ANDREW
IPC: C12N9/34
Filed: 2019-12-03
Abstract: Compositions and methods for treating enzyme-deficiency diseases are disclosed. Multidomain therapeutic proteins containing an internalization effector binding domain and a lysosomal replacement enzyme activity are disclosed. The multidomain therapeutic proteins are capable of entering cells, segregating to the lysosome, and delivering the replacement enzyme activity to the lysosome.
Patent PH-12020551177-A1 (PH)
Title: Electrical amplification systems through resonance
Inventor: ALCON ANDREW R
IPC: H01L41/04
Filed: 2020-07-30
Abstract: A device, method and process to induce and amplify electrical energy through resonance and vibration, the device producing voltage and current generation with amplification within electrical motors, primarily DC motors, by vibration of the motors, including the capability to tune and control the regulation of the output current and voltage by the addition of electrical components with predictable results.
Patent PH-12020551528-A1 (PH)
Title: Biomass fuel production method
Inventor: KIMITSUKA GEN
IPC: C10J3/00
Filed: 2020-09-22
Abstract: In order to obtain a biomass fuel manufacturing method wherein a biomass resource can be reliably and efficiently heated without irregularity in a prescribed temperature range, and an oil/fat of the biomass resource can be made into a biomass fuel without waste, the present invention provides a biomass fuel manufacturing method for heat treating a biomass resource to obtain a biomass fuel, wherein heat treatment of a biomass resource 2 is performed by using a heating means 6 to heat the interior of a heat treatment tank 3 and using a superheated vapor supply means 4 to supply a superheated vapor into the heat treatment tank 3 that has been heated by the heating means 6 and is in an unsealed condition, and the supply of the superheated vapor into the heat treatment tank 3 begins at least before the temperature within the heat treatment tank 3 reaches the ignition temperature of the biomass resource 2, and is performed continuously at least until the completion of the heat treatment of the biomass resource.
Patent PH-12020551760-A1 (PH)
Title: Pyridazinones as parp7 inhibitors
Inventor: VASBINDER MELISSA MARIE
IPC: C07D487/10
Filed: 2020-10-22
Abstract: The present invention relates to pyridazinones and related compounds of Formula I which are inhibitors of PARP7 and are useful in the treatment of cancer.
Patent PH-12021551539-A1 (PH)
Title: Manufacturing of a web of packaging material
Inventor: BODIN CRISTIAN
IPC: D04H1/74
Filed: 2021-06-28
Abstract: The present invention relates to an arrangement (100) and a method (400) for manufacturing of a web of packaging material for an oral pouched snuff product. The web is a salivapermeable nonwoven web comprising fibres, whereof 0 pcnt - 95 pcnt of said fibres are of a first type and 5 pcnt -100 pcnt of a second type, the fibres of the first type being cellulose-based staple fibres, and the fibres of the second type being thermoplastic fibres, which are meltable and/or softenable at least at the surface. The arrangement comprises a carding unit (110) for carding the fibres to form a pre-web, an air-through bonding unit (130) for bonding the pre-web by means of at least partial melting and/or softening of the fibres of the second type to form the web, and a calendering unit (140) for surface treatment of the web. The method comprises: a) carding the fibres to form a pre-web, b) bonding the preweb by blowing air through the pre-web to at least partially melt and/or soften the fibres of the second type to form the web of packaging material and c) smooth calendering of the web.
Patent DE-102004003566-A1 (DE)
Title: Weather strip for sliding roof of motor vehicle, has accommodation hole formed on bottom part along longitudinal direction of weather strip and having openings opened along direction of main body to accommodate edge of base member
Inventor: OTA TOMOKI
IPC: B60J10/82
Filed: 2004-01-23
Abstract: An accommodation hole, formed on a bottom part (28) along the longitudinal direction of a weather strip (20), has openings opened along the direction of a main body (20a) to accommodate the edge of a base member.
Patent DE-102004005895-A1 (DE)
Title: Throttle drive for draining e.g. rainwater collection tank, comprises piston connected via rotary bearing to counterweight
IPC: E03F5/10
Filed: 2004-02-05
Abstract: The drive has at least one piston (5) connected to at least one counterweight (3) via a rotary bearing (1) so that an increase in water pressure in the axial direction of the piston causes the counterweight to rise. A reduction in this pressure causes this piston to return towards its original position.
Patent DE-102004007054-A1 (DE)
Title: Gulls wing door for saloon car has three linked sections to open in a confined space
Inventor: ELLENRIEDER GUNTHER
IPC: B60J5/04
Filed: 2004-02-13
Abstract: An improved design of gulls wing door for a saloon car is made in three sections; a roof section (3) with a roof mounted hinge (8) near to the centre of the roof, a window section (4) and a door sections (5). The three sections are linked by parallel hinges to enable the door to unfold in a restricted space, either restricted beside the vehicle or under a low headroom. The separate sections can be fitted with servo drives to open in the selected modes. A proximity sensor detects the space beside/above the vehicle and sets the opening mode.
Patent DE-102004010089-A1 (DE)
Title: Transportfahrzeug für Rollstühle
Inventor: LOSCH WERNER
IPC: A61G5/10
Filed: 2004-02-27
Abstract: Die Erfindung bezieht sich auf ein treppengängiges Transportfahrzeug für Rollstühle mit einem im Wesentlichen rechteckförmigen Chassis. Es weist auf jeder Längsseite Rollen und ein auf diesen angetriebenes Raupenendlosband auf. Dieses ist mit einer am Chassis angebrachten Aufnahmevorrichtung zum lösbaren Halten des Rollstuhls versehen, der während der Treppenfahrt des Fahrzeugs in eine horizontale Normalsitzlage anbringbar ist. Es ist dadurch gekennzeichnet, dass die Aufnahmevorrichtung durch eine Schale gebildet ist, die zwischen den beiden Raupenbändern am Chassis drehbar befestigt ist und von einem Schmalende des Chassis aus durch den Rollstuhl zugänglich ist. Außerdem wird deren Drehposition durch einen Schalenantrieb abhängig von der Lage des Fahrzeugs derart automatisch gesteuert, dass die genannte Sitzlage stets gewahrt ist.
Patent DE-102004010226-A1 (DE)
Title: Crystal backscattered electron pattern processing improvement procedure for crystallography uses electron lens or mirror to magnify divergence of scattered paths
Inventor: WENDT ULRICH
IPC: G01N23/203
Filed: 2004-02-29
Abstract: A crystal (a) backscattered electron pattern processing (e) improvement procedure uses an electron optics lens or mirror (f) to magnify the divergence of scattered paths (c) in a preset regions according to a selectable function : Independent claims are included for equipment using the procedure.
Patent DE-102004012781-A1 (DE)
Title: Backlight device for liquid crystal display, has adjacent regions of light guide illuminated by independently controllable light sources
Inventor: FOLKERTS WIEPKE
IPC: F21V8/00
Filed: 2004-03-15
Abstract: A light guide includes a number of adjacent regions (2a,2b) for illuminating corresponding portions of the liquid crystal screen. Each region is illuminated with an independently controllable light source (1a,1b). The light source of each region is preferably arranged at an edge opposing a common edge of the two regions. An independent claim is included for a method of operating a liquid crystal display device.
Patent DE-102004022235-A1 (DE)
Title: Paper sheet delivery device for printing machine, has arc brake with suction chamber, air inlet and suction ledge extending over length of brake so that sheet is elongated laterally, where ledge is adjustably arranged in curvature direction
Inventor: FISCHER UWE
IPC: B65H29/68
Filed: 2004-05-04
Abstract: The device has an arc brake overlapping whole breath of a sheet stack for realizing force on a lower side of a printed sheet. The brake is provided with a suction chamber, a suction air inlet and a fixed suction ledge (10) securely extending over the length of the brake, so that the acquired printed sheet is elongated laterally. The ledge is adjustably arranged in a curvature direction (R) against a rear edge of the sheet stack.
Patent DE-102004028748-A1 (DE)
Title: Engine control method for a motor vehicle combines gas pedal control of freewheeling and braking with a pressure point
Inventor: DENKHAUS ULRICH
IPC: B60W10/02
Filed: 2004-06-14
Abstract: A gas pedal (GP) can only be moved further from a pressure point (2) against greater resistance towards greater engine output. If it falls short of this, flow of force (FOF) between engine and drive wheels is interrupted. If it exceeds this, FOF is resumed. Freewheeling switches off if the GP is held in an inactive position (1), and switched on if the GP is removed from the inactive position.
Patent DE-102004029423-A1 (DE)
Title: Halbleiterlaserelement
Inventor: TAKASE TADASHI
IPC: H01S3/04
Filed: 2004-06-18
Abstract: Um
ein Halbleiterlaserelement mit einem Aufbau bereitzustellen, mit
dem die Unterdrückung der
Erzeugung eines Kinks selbst in dem Fall möglich ist, in dem FFPx groß gemacht
ist, besitzt ein Halbleiterlaserelement eine Kammstruktur (engl.
ridge structure), bei der eine aktive Schicht (3) zwischen eine
Halbleiterschicht (2) eines Leitfähigkeitstyps und eine Halbleiterschicht
(4) des anderen Leitfähigkeitstyps
mit einem Kamm (9) vorgesehen ist und Fensterbereiche, die Nicht-Verstärkungsbereiche
sind, sind an beiden Enden davon vorgesehen, wobei ein Unterschied
im Äquivalentbrechungsindex
zwischen dem Kamm (9) und Abschnitten (9s) auf beiden Seiten davon
in jedem der Fensterbereiche größer ist
als ein Unterschied im Äquivalentbrechungsindex
zwischen dem Kamm (9) und Abschnitten (9s) auf beiden Seiten davon
in einem Verstärkungsbereich.
Patent DE-102004031545-A1 (DE)
Title: System for preventing and removing environmental contamination for containers used for transporting oil and oil-containing material comprises heavy oil or light oil container made from double-wall panels
Inventor: SIEBERT HUGO
IPC: B65D90/22
Filed: 2004-06-29
Abstract: A system for preventing and removing environmental contamination comprises a heavy oil or light oil container made from double-wall panels. Preferred Features: The double-wall panels are made from steel with both walls connected by different bars at a distance from each other. The system has predetermined breaking points. The inner hollow chambers of the container wall are filled with a mixture of oil binder and oil-decomposing bacteria.
Patent DE-102004031689-A1 (DE)
Title: Light-emitting diode device, has e.g. pulse-width modulator for supplying current to two antiparallel-connected LEDs
Inventor: KIRCHBERGER GUENTER
IPC: H05B37/02
Filed: 2004-06-30
Abstract: The device comprises two diodes (1,2) which are connected in antiparallel. A pulse-width modulator (8) is provided for supplying current to the light-emitting diodes in alternating directions. The diodes are preferably mounted in the same housing, and/or emit light of different wavelengths, e.g. red and blue. A luminescence-conversion material may be provided.
Patent DE-102004037268-A1 (DE)
Title: Elongated wood or timber unit measuring procedure, involves measuring timber unit in passage in contact-less manner with measuring device that measures progression of side that turns away from stopper
Inventor: HOLLMANN FRANK
IPC: B27B27/02
Filed: 2004-07-31
Abstract: The procedure involves measuring a timber unit (2) in a passage in a contact-less manner with a measuring device (4) that measures progression of a side that turns away from a stopper (3). The timber unit has a concave side (2.1) against the stopper that rests against the turning away side. The timber unit is moved relative to the measuring device along the stopper. The stopper forms a vertical contact surface for the timber unit. An independent claim is also included for a device for measuring an elongated wood or timber unit.
Patent DE-102004037860-A1 (DE)
Title: Turmormarker zur Diagnose von Karzinomen und/oder davon abstammender Metastasen
Inventor: BRUECKL WOLFGANG
IPC: C12Q1/68
Filed: 2004-08-04
Abstract: Die Erfindung betrifft ein Verfahren (i) zur Erkennung eines Karzinoms, insbesondere eines Adenokarzinoms, bevorzugterweise eines gastrointestinalen Karzinoms und besonders bevorzugt eines kolorektalen Karzinoms, (ii) zur Prädiktion von Metastasen, vorzugsweise von Lebermetastasen, in Abhängigkeit eines primären Kolonkarzinoms und/oder (iii) zur Prädiktion des Ansprechens von Metastasen auf eine 5-Fluorouracil-haltige Chemotherapie, umfassend die Bestimmung eines Genexpressionsprofils von 120 Markergenen oder einer Auswahl daraus.
Patent DE-102004039387-A1 (DE)
Title: Deckel für einen Behälter zur Lagerung und/oder Bereitstellung und/oder zum Transport von feuchtigkeitsempfindlichen Materialien
Inventor: BECKER-WEIMANN KLAUS
IPC: B65D8/02
Filed: 2004-08-13
Abstract: Es wird ein Deckel (1) für einen Behälter, insbesondere ein Fass, zur Lagerung und/oder Bereitstellung und/oder zum Transport von feuchtigkeitsempfindlichen Materialien vorgeschlagen, dadurch gekennzeichnet, dass an der Innenseite des Deckels (1) eine mechanische Halteeinrichtung (2) vorgesehen ist, die einen zum Behälterinneren wasserdampfdurchlässigen Teilraum umschließt, in dem ein oder mehrere mit einem partikelförmigen Trocknungsmittel gefüllte Beutel eingebracht sind oder der direkten Befestigung von einem oder mehreren mit partikelförmigem Trocknungsmittel gefüllten Beuteln dient.
Patent DE-102004040470-A1 (DE)
Title: Bremssteuerungsvorrichtung
Inventor: YOKOYAMA TAKAHISA
IPC: B60T13/74
Filed: 2004-08-20
Abstract: Die
Bremssteuerungsvorrichtung richtet eine Soll-Verzögerung 1
gemäß einem
Betätigungsbetrag
von dem Bremspedal 1 ein. Sie berechnet eine weitere Soll-Verzögerung 2
auf der Grundlage der Soll-Verzögerung
1. Bei dieser Berechnung werden Grenzwerte der Verzögerungsanstiegs-
und Verringerungsgradienten mit Bezug auf die Soll-Verzögerung 1
auf der Grundlage von der Soll-Verzögerung 1 eingerichtet und wird
dann die Soll-Verzögerung
2 durch Korrigieren der Soll-Verzögerung 1 auf der Grundlage
der gebildeten Verzögerungsanstiegs- und
Verringerungsgradienten erhalten. Demgemäß werden die Verzögerungsanstiegs-/-verringerungsgradienten
klein, wenn die Bremsung sanft ist. Das macht es möglich, eine abrupte Änderung
der Bremskraft zum Erzielen einer sanften Bremssteuerung einzuschränken. Des
weiteren wird der Verzögerungsanstiegs-/-verringerungsgradient
größer, wenn
die Bremsung abrupt ist. Demgemäß ist es
möglich, eine
große Änderung
der Bremskraft zum Vorsehen eines guten Ansprechverhaltens zu bilden.
Patent DE-102004043438-A1 (DE)
Title: Determination of the error frequency distribution in the transmission of CRC assured data by use of a recursive equation with a data block length equal to a specified maximum cycle length
Inventor: MERCHANT KAMAL
IPC: G06F17/18
Filed: 2004-09-06
Abstract: Method for determining the error frequency distribution in the transmission of CRC assured data in which the distribution is determined using a recursive equation with a data block length equal to the maximum cycle length of 2n> >= 1, where n is the code length and selected polynomial is primitive.
Patent DE-102004049509-A1 (DE)
Title: Dental suction device, comprising threaded lower segment for joining of disposable tube
Inventor: HIRTE LIANE
IPC: A61C17/08
Filed: 2004-10-11
Abstract: The suction device (1) can be used during dental surgery and is designed as a metal tube with a plastic coating for an easy sterilization. It has a particularly small diameter for a precise guiding. The lower area (1a) is provided with a threaded outer surface (2) facilitating the joining of a disposable suction tube. The upper area (1b) can be connected to the electric drive.
Patent DE-102004050262-A1 (DE)
Title: Haushaltsmaschine mit einem Motor
Inventor: KRAFFZIK HANS-JUERGEN
IPC: A47L15/42
Filed: 2004-10-14
Abstract: Die Erfindung betrifft eine Haushaltsmaschine, insbesondere Geschirrspüler oder Waschmaschine, mit einem Motor, wobei wenigstens eine mindestens eine Dämpfungsvorrichtung umfassende Halteeinheit zum verstellbaren Halten des Motors vorgesehen ist, die dadurch gekennzeichnet ist, dass die Dämpfungsvorrichtung wenigstens ein erstes Dämpfungselement mit einer ersten Dämpfung und ein zweites Dämpfungselement mit einer zweiten Dämpfung aufweist.
Patent DE-102004051181-A1 (DE)
Title: Producing a coated monolith useful in exhaust gas particulate filters and catalytic converters comprises coating a curved monolith with excess composite material to compensate for the curvature
Inventor: LOTZGESELLE GERD
IPC: B28B11/04
Filed: 2004-10-20
Abstract: Producing a coated monolith (1) from an uncoated monolith (2) with a predetermined axial curvature comprises coating the side face (7) of the monolith with a composite material (3) in the form of a paste in a predetermined excess such that the local thickness of the coating is a function of the curvature at the coating site and a predetermined outside diameter (dG) will be attained after shrinkage during hardening, and then hardening the coating. Independent claims are also included for the following: (1) an exhaust gas particulate filter for an internal combustion engine, comprising a coated monolith as above in a housing; and (2) an exhaust gas catalytic converter for an internal combustion engine, comprising a coated monolith as above in a housing.
Patent DE-102004053153-A1 (DE)
Title: Miniature light bulb holder for use in party, has case with contacts provided within riser in case, and electrically connected with contact and metal bushings to which bulb is attached
Inventor: HACHAM WLADIMIR
IPC: H01R33/22
Filed: 2004-10-21
Abstract: The holder has a contact plate (3) for cooperating the central contacts (5,6) of a lamp socket, where the height of the contact plate amounts approximately to half the height of the holder case, while fixing on a base part. The case has contacts (8,9), which are provided within a riser in the case and electrically connected with a contact (7a) and metal bushings to which a bulb is attached.
Patent DE-102004059335-A1 (DE)
Title: Air cooler/Low temperature-heating body for air circulation motor
Inventor: ROSEL VALENTIN
IPC: F24D19/00
Filed: 2004-12-09
Abstract: u The air cooler/low temperature-heating body comprises a number of rigid-walled neighbouring plates (1) that are connected together, via spacer rings, by union connections (11). There is a continuous air-gap (3) of between 3 to 25 millimetres between the plates. The plate section (1.1) has a radial ventilation air wheel (2) with a regulating outer or inner running electric motor (2.1) that is screwed on to the outer plate via rubber insulation (2.2) as well as being screwed to the plate packet rear side of an air-suction ring (4). There is an elevation profile in the plates~ inner hollow chamber which is fixed via point welding, whilst there is an automatic regulation valve for the heating & cooling plant (11.1) built around the connections. The suction ring may have an outer air mixture cylinder (5) with an outer air valve (5.1).
Patent DE-102005002001-A1 (DE)
Title: Verschraubbare Kabelabdichtung
Inventor: KUHN PETER
IPC: H02G3/06
Filed: 2005-01-15
Abstract: Die Erfindung betrifft eine verschraubbare Kabelabdichtung (1) mit einer in einem Bauteil (2) vorgesehenen Gewindeöffnung, in der eine durchmesserreduzierte Druckfläche vorgesehen ist, mit einem in die Gewindeöffnung einsetzbaren und verformbaren Dichtring (3), einer daran anschließenden Druckscheibe (4) und einer in das Gewinde einschraubbaren Hohlschraube (5), wobei erfindungsgemäß vorgesehen ist, dass die Druckscheibe (4) über zumindest einen Steg (6), vorzugsweise zwei Stege (6), an der Hohlschraube (5) befestigt ist.
Patent DE-102005002433-A1 (DE)
Title: Membranspeicher
Inventor: LENZ RENE
IPC: B60T13/14
Filed: 2005-01-19
Abstract: Die Erfindung betrifft einen Membranspeicher für eine schlupfgeregelte Fahrzeugbremsanlage, welcher in einer hydraulischen Verbindung zwischen einer Radbremse und einer hydraulischen Pumpe angeordnet ist, mit einem, in einer Gehäusebohrung eingespannt angeordneten Medientrennelement, umfassend eine Mebran aus elastischem Werkstoff, die in Bezug auf einen Druckmitteleinlass und/oder Druckmittelauslass zwecks Druckmittelaufnahme konkav ausgebildet ist. DOLLAR A Der Kern der Erfindung liegt darin begründet, dass die Membran mittelbar unter Zwischenlage eines Membrantellers von einer Speicherfeder beaufschlagt ist und dass der Membranteller in Bezug auf den Druckmitteleinlass und/oder Druckmittelauslass konkav ausgebildet ist.
Patent DE-102005009004-A1 (DE)
Title: Verfahren zur Herstellung von Platten, welche aus einem Plastikmaterial gefertigt sind mit Teilen, welche durch Injektionskompression überformt werden
Inventor: ROSSANESE AFRO
IPC: B29C45/16
Filed: 2005-02-28
Abstract: Ein Verfahren zur Herstellung von Platten aus Material (1) mit überformten Teilen (2), welche aus Plastikmaterial mit verschiedenen Dimensionen, Formen und Farben hergestellt sind, durch eine erste Injektion zur Bildung der Platte (1) und einer nachfolgenden Injektionskompression zum Überformen der Teile (2) auf der Platte (1). Jede Injektion kann bequem ausgeführt werden mit sequentiell gesteuerten Injektionspunkten (Figur 1).
Patent DE-102005009492-A1 (DE)
Title: Fixing element for fractured bone, comprising wedge part with grooves for accommodation of thread or wire
Inventor: LOB GUENTER
IPC: A61B17/58
Filed: 2005-02-24
Abstract: The cylindrical fixing element is split lengthwise into two identical halves (10,12). Each of them is provided with a recess (36) and an extension (32) to be engaged in order avoid sliding. A wedge element (14) with a rounded tip can be pushed between the parts (10,12). Two grooves located at the surface of the wedge element (14) facilitate the insertion of a thread or wire (60,62) to be used for pulling the element (14) into position.