baber/WOPTO huggingface dataset:
Patent NZ-276892-A (NZ)
Title: Quinoxalinedione derivatives, preparation and use in pharmaceutical compositions thereof
Inventor: CAI SUI XIONG
IPC: A61K51/04
Filed: 1994-11-07
Abstract: hese alkyl or azido-substituted 1,4-dihydroquinoxaline-2,3-diones or pharmaceutically acceptable salts thereof are useful in of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia, and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, and Down's syndrome, treating or preventing the adverse consequences of the hyperactivity of the excitatory amino acids, as well as treating anxiety, chronic pain, convulsions, and inducing anesthesia by administering to an animal in need of such treatment which have high binding to the glycine receptor.
Patent NZ-287857-A (NZ)
Title: Delivery of water insoluble active agents using tocopherol as emulsifier or solvent
Inventor: SONNE MATTE RYDAHL
IPC: A61K9/00
Filed: 1995-05-15
Abstract: The present invention provides the use of a tocopherol or a derivative thereof as a solvent and/or emulsifier for substantially insoluble and sparingly soluble biologically active agents, especially in the manufacture of pharmaceutical compositions. Such compositions are particularly suitable for transmucosal, and especially intranasal or rectal administration, or administration via the oral cavity.
Patent NZ-315933-A (NZ)
Title: Multi-ply cellulosic paper product which are joined together
Inventor: WEGELE GEORGE VINCENT
IPC: A47K7/00
Filed: 1996-08-16
Abstract: isclosed is a multi-ply paper product.  One or both of the plies may have embossments protruding towards and contacting the other ply  The plies are adhesively joined, preferably at such embossments.  The adhesive is selected from a composition that advantageously provides a minimum wet ply bond strength and a dry ply bond strength which falls within a particularly desired range.
Patent NZ-329018-A (NZ)
Title: Extracting glycogen from Green Shell Mussels and the use of the glycogen as a food supplement or additive or in the treatment of inflammatory diseases such as arthritis.
Inventor: SLIM GEORGE CHARLES
IPC: A23J1/04
Filed: 1998-12-22
Abstract: A process for obtaining high purity glycogen form mussels comprising: 1) treating the mussels with a proteolytic enzyme preferably papin, pepsin or Alcalase, in water for approximately 3 hours at approximately 70oC, to give a slurry of solid residue and an aqueous solution of glycogen; 2) separating the solid residue from the aqueous solution by adding ethanol; 3) recovering the glycogen from the aqueous solution, said glycogen exhibiting anti-inflammatory activity.  Also claimed is the use of a glycogen produced by this compound for treating inflammatory diseases such as arthritis, or as a food additive or supplement.
Patent NZ-337183-A (NZ)
Title: 1-(isoquinolin-1-yl)-4-(1-phenylmethyl)piperazines; dopamine receptor subtype specific ligands useful for the treatment of psychotic disorders
Inventor: CHEN XI
IPC: A61K31/496
Filed: 1998-03-03
Abstract: The compounds of the formula shown or pharmaceutically acceptable addition salts thereof, and the use of these compounds in the manufacture of medicaments for the treatment of psychotic disorders, where: Ar represents, aryl or heteroaryl, each of which is optionally substituted with R3 and/or R4; R1 and R2 independently represent hydrogen, halogen, C1-C6 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, hydroxy, amino, mono- or di(C1-C6)alkyl amino, cyano or trifluoromethyl; R3 and R4 are the same or different and represent hydrogen, halogen, hydroxy, C1-C6 alkyl, trifluoromethyl, trifluoromethoxy or SO2NH2, provided that not both R3 and R4 are hydrogen when Ar is phenyl; or R3 and R4 together with the atoms to which they are attached represent a ring having 5-7 atoms; and R5 represents hydrogen or C1-C6 alkyl.
Patent NZ-503945-A (NZ)
Title: Metalloprotease-inhibiting amide derivatives
Inventor: TAIWO YETUNDE OLABISI
IPC: C07F9/36
Filed: 1998-07-27
Abstract: The compound of formula (I), wherein: A is SO2Ar, COAr, CONHAr, PORAr, where Ar is monocyclic or bicyclic aromatic or a monocyclic or bicyclic heteroaromatic, substituted or unsubstituted; R1 is alkyl or hydrogen; R2, R3, and R4 are each independently chosen from hydrogen, alkyl, aryl, heteroaryl, aryl-alkyl, alkoxy-alkyl, heterocycle, and heterocycle alkyl, and these substituents may be substituted or unsubstituted; or rings can be formed by R2 and R3, R1 and R2 or R3 and R4; X is a bond, a (C1-C6)alkyl, CO, or a heteroatom chosen from 0, NZ, S, SO, or SO2; Y is a bond, a (C1-C6)alkyl, CO,CONH, or a heteroatom chosen from NZ, S, SO, or SO2; and Z is hydrogen, COR4, CONHR4, R4, CSR4, CSNHR4, and S02R4. The following proviso applies to the compounds of formula (I): When A is SO2Ar and Ar is substituted phenyl or substituted biphenyl, the substitution is with hydroxy, alkoxy, phenoxy, nitro, halo, or phenyl. Optical isomers, diastereoisomers, enantiomers, salts, and biohydrolyzable amides, esters and imides of the compounds of formula (I) are also described. Also described is a pharmaceutical composition comprising the compound of formula (I) and a pharmaceutically-acceptable carrier. The compound of formula (I) is useful for preventing or treating diseases associated with unwanted metalloproteinase activity in mammalian subjects.
Patent NZ-508758-A (NZ)
Title: Substituted 2-(pyrazol-5-yl)-pyridine or pyrimidine derivatives useful as herbicidal agents
Inventor: KLEEMAN AXEL
IPC: C07D401/14
Filed: 2000-12-08
Abstract: 2-Pyrazolyl-6-aryloxy-pyridine or pyrimidine derivative or an agriculturally acceptable salt or N-oxide thereof has the formula (I) wherein: A is optionally substituted aryl or 5- or 6-membered nitrogen- or sulfur-containing heteroaromatic or a difluorobenzodioxolyl; Z is N or CR6; X is -O-, -S-, -CH2O- or -CH2S-; R1 and R2 are independently hydrogen, halogen, haloalkyl, haloalkoxy, cyano, nitro or an optionally substituted alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, alkoxyalkoxy or -S(O)n-R7, -NR8R9 or R10O-CY-; n is 0, 1 or 2;  R7 is alkyl or haloalkyl; R8 and R9 are each independently hydrogen, alkyl, alkenyl, aralkyl or aryl; R10 is an alkyl; Y is O or S; R3 is hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxyalkyl, haloalkyl, cyano, nitro or -NR11R12; R11 and R12 are each independently hydrogen, alkyl, alkenyl, aralkyl or aryl; R4 is hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, alkoxyalkoxy, haloalkyl, haloalkoxy, cyano, nitro or -S(O)m-R13; m is 0, 1 or 2; R13 is alkyl or haloalkyl; R5 is hydrogen, alkyl, alkenyl, alkynyl, alkoxyalkyl, cycloalkyl, haloalkyl, haloalkenyl, cyanoalkyl or cyano and R6 is hydrogen with the proviso that a) R5 and R6 both is hydrogen and/or b) R2 is halogen, optionally substituted alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, alkoxyalkoxy group, or haloalkyl, haloalkoxy, cyano, nitro or -S(O)n-R7, -NR8R9 or R10O-CY-; n is 0, 1 or 2; R7 is alkyl or haloalkyl group; in which R8 and R8 are each independently hydrogen, alkyl, alkenyl, aralkyl or aryl; R10 is alkyl and Y is O or S in the event that Z is CR and A is an optionally substituted aryl or optionally substituted 6-membered nitrogen- or sulfur-containing heteroaromatic. A herbicidal composition thereof is also described.
Patent NZ-512182-A (NZ)
Title: Method of producing fractions containing a high concentration of milk basic cystatin and decomposition products thereof
Inventor: SERIZAWA ATSUSHI
IPC: A23K50/15
Filed: 2001-06-07
Abstract: A method of producing a fraction of milk basic cystatin or its decomposition product.  The steps of the method involve: a) preparing a composition containing a milk-derived basic protein fraction; b) contacting the composition with a carrier containing a sulfuric acid group; c) recovering a fraction which is not absorbed onto the carrier; d) subjecting the fraction to ultrafiltration using a membrane having a cut-off molecular weight of 10-50kDa; and e) recovering the permeate from the ultrafiltration membrane to recover a fraction containing milk basic cystatin from the permeate.
Patent NZ-515334-A (NZ)
Title: Fold and glue stacking container with side access
Inventor: SHEFFER PHIL B
IPC: B65D21/032
Filed: 1999-05-07
Abstract: A one-piece fold-and-glue container having corners reinforced by extensions (33) that fold over and compress self-erecting gusset corner joints (40), and cutouts (25) in each of the four front, back, and end walls is disclosed.  The end walls have outer end wall panels (26) integrally extending from the bottom and joined adjacent to the front or back to extensions (33) each having a protruding tab (39) at a free end for locking into the bottom when each extension (33) is folded over a corresponding gusset joint (40).  Adjacent to the junctions between the extensions (33) and the outer end walls (26), a registration tab (35) is cut in each extension (33) to register with a corresponding opening (64) in the bottom of another container stacked on the container.  The extensions (33) can have two or more thicknesses of material folded laterally inward and glued against one another for added reinforcement.
Patent NZ-521333-A (NZ)
Title: Bearing for an adjustable rotor blade on a wind energy plant
Inventor: WOBBEN ALOYS
IPC: F03D11/00
Filed: 2001-02-22
Abstract: The mounting of an adjustable rotor blade on the rotor hub of a wind power installation has as an adjusting drive pivot bearing, a rolling bearing for the transmission of high axial forces and great flexural moments in the event of slight relative movements between the co-operating bearing components. It comprises a bearing race for the one co-operating bearing component, which receives in positively locking relationship two radially mutually displaced rows of rolling bodies, and a bearing race for the other co-operating bearing component, which embraces them in a U-shape in cross-section. The bearing race for the rotor blade forming the other co-operating bearing component comprises two races (10, 12) of different diameters, which are fixed independently of each other to the rotor blade (3). The circular root of the hollow rotor blade (3) is forked to form two shell portions (3a, 3b) and each shell portion is fixed to one of the two races (10, 12) of the one bearing race.
Patent NZ-521566-A (NZ)
Title: Use of polyphosphate as a tooth erosion inhibitor in acidic compositions
Inventor: BAKER NICOLA JANE
IPC: A23L1/304
Filed: 2001-03-23
Abstract: A polyphosphate, which is a phosphate polymer wherein the number of phosphate groups (n) is at least 3, is used as a tooth erosion inhibitor in the manufacture of an orally administrable acidic composition. Preferably the polyphosphate is sodium polyphosphate.
Patent NZ-530781-A (NZ)
Title: Valved male luer
Inventor: DOYLE MARK C
IPC: A61M39/10
Filed: 2002-08-09
Abstract: Disclosed is a male luer connector device that attaches to any standard female luer valve to open a flow channel between the two luers. The male luer is comprised of a tubular housing element, a resilient member contained within the housing and extending within an inner tubular portion defined in the housing, a resilient member that extends within the inner tubular portion of the housing, and a valve member attached to the resilient member that seals the tubular portion. When the male luer is engaged with any standard female luer, a female luer connector device drives the resilient member of the male luer into a compressed position to open the forward end of the male luer and permit liquid flow between the luers.
Patent NZ-531920-A (NZ)
Title: Protective toecap, particularly for safety shoes
Inventor: FRULLA CLAUDIO
IPC: A43B23/08
Filed: 2002-10-24
Abstract: A protective toecap particularly for safety shoes, which has the particularity that it comprises a body (1) made of aluminium alloy with an elongation coefficient of more than 15%. The body (1) delimits a space with a rear opening and a lower opening and forms an upper portion (2) that blends with a substantially vertical rim (3) that affects the front portion and lateral portions (3b) that mutually diverge. There is also a lower rim (4), which delimits the lower opening and is connected to the lower end of the front portion and of the lateral portions (3b).
Patent NZ-533445-A (NZ)
Title: Process for the preparation of 2-(6-substituted-1,3-dioxane-4-yl) acetic acid derivates
Inventor: HOF ROBERT PATRICK
IPC: C07B61/00
Filed: 2002-12-09
Abstract: Process for the preparation of a 2-(6-substituted)-1,3-dioxane-4-yI) acetic acid derivative according to formula (1), wherein R1, R2 and R3 are each independently a C1-4 alky group or wherein R1 and R2 together with the C-atom to which they are bound form a 5- or 6- membered cycloalkyl and wherein Y stands for RA-CO- or for RB-SO2- with RA, RB are chosen from the group of alkyl or aryl with 1-12 C-atoms, from its corresponding 2-(6-substituted)-1,3-dioxane-4-yl) acetic acid derivative according to formula (2), wherein R1, R2 and R3 are as defined above and wherein X stands for a halogen, in the presence of a phase transfer catalyst and an oxylating agent, characterized in that a quarternary phosphonium ion according to formula (3), wherein R4, R5, R6, R7 each independently stand for an alkyl, cycloalkyl, aralkyl or aryl with 1 to 12 C-atoms, is used as a phase transfer catalyst and an ion according to formula (4), OY-, wherein Y is as defined above, is used as an oxylating agent.
Patent NZ-534310-A (NZ)
Title: Albumin-fused anti-angiogenesis peptides
Inventor: MERTINS PETER
IPC: A61K48/00
Filed: 2003-02-07
Abstract: Proteins comprising angiogenesis inhibiting peptides, such as endostatin peptides (including, but not limited to, fragments and variants thereof), which exhibit anti-retroviral activity, fused or conjugated to albumin (including, but not limited to fragments or variants of albumin). These fusion proteins are herein collectively referred to as "albumin fusion proteins of the invention." These fusion proteins are herein collectively referred to as "albumin fusion proteins of the invention." These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. Also disclosed are therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. Nucleic acid molecules encoding the albumin fusion proteinsof the invention, as well as vectors containing these nucleic acuds, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells are discussed. Compositions and methods for inhibiting proliferation of vascular endothelial cells and tumor aniogenesis induced cell fusion, methods of preventing growth of, or promoting regression of, primary tumors and metastases; and for treating cancer, diabetic retinophathy, progressive macular degeneration or rheumatoid arthritis are disclosed.
Patent NZ-536990-A (NZ)
Title: Plastic bag and film for bag, with sealing strips sealed to each other at ends
Inventor: OLSEN LAWRENCE JOSEPH
Filed: 1999-03-09
Abstract: A bag, film and bag manufacturing method are disclosed. The bag has sealing strips which have complementary inter-engaging profiles within the bag mouth. These strips are sealed to each other at their ends. A tamper-evident region is provided above the sealed bag mouth, typically with perforations 18 extending across the bag. (62) Divided Out of 526550
Patent NZ-538203-A (NZ)
Title: An angled sash adaptor
Inventor: HEADS FRANCIS XAVIER
Filed: 2005-02-11
Abstract: A sliding window or a sliding door traditionally connects with a jamb or with another member at an angle of 0  (i.e. in-line) or 90  (i.e. at right angles). Disclosed is a sliding window or a sliding door that can meet with another window/door or a jamb or other type of member at an angle other than 0  or 90  and allows windows and doors to meet various angles without requiring major modifications to the assembly. This is done by providing an angle adapter that can be snapped fitted to the edge of a window or door and which presents an outer face that will be parallel to the adjacent window or door. A number of different angles adapters can be provided each with a different angle to accommodate various desired angles between the sliding window and sliding door. In this manner, the window or door does not require major redesigning, and the only thing that needs to be changed is the angle adapter.
Patent NZ-547383-A (NZ)
Title: A method of inducing melanogenesis in humans with MC1R variant alleles
Inventor: HUMPHREY STUART MICHAEL
IPC: A61K38/34
Filed: 2004-11-23
Abstract: Disclosed is the use of an alpha-MSH analogue in the manufacture of a preparation for inducing tanning or reducing the risk of skin cancer in a human subject having an MC1R variant allele associated with loss of or diminished receptor function, wherein said induction of tanning is through the induction of melanogenesis by melanocytes in the skin or other epidermal tissue of the subject.
Patent NZ-552005-A (NZ)
Title: Investigation of Vehicle Glazing Panels using an illuminating electromagnetic radiation
Inventor: DAVIES CHRISTOPHER JOHN
IPC: G01N21/35
Filed: 2005-06-27
Abstract: A glazing panel 2 investigation system comprising i) a hand held device, including a dark space chamber 5, an electronic infra-red image capture device 4 positioned toward a proximal end of the dark space chamber 5, a compressible light seal 11 provided at the distal end of the device to enable the hand held device to be held against the glazing panel 2 in the region of a target zone to be investigated, an annular array of infra-red light emitters positioned peripherally at the distal end of the dark space chamber 5, ii) a processor 7 to process data related to captured image data from the electronic Infrared image capture device, and iii) an output device in communication with the processor 7 and arranged to produce an output related to the condition of the glazing panel 2 at the target zone.
Patent NZ-555848-A (NZ)
Title: Improved wind generator
Inventor: WANGFORD JONATHAN GRAHAM
IPC: F01D1/04
Filed: 2007-06-12
Abstract: A wind turbine comprising a plurality of feathering blades, where each blade includes a shape having a leading and a trailing edge, and the blade has a centre of pressure that is displaced from the blade pitch axis in the direction of the trailing edge of the blade so that wind force on the blade urges feathering of the blade, a governor for controlling the pitch angle of the blades according to the speed of rotation of the turbine, and an elastic linkage between the governor and the blades, the linkage urging the blades toward the pitch position set by the governor, allowing pitching of the blades toward a more feathered position than a position set by the governor against an elastic return force, and not allowing substantial pitching of the blades to a less feathered position than the position set by the governor; such that the governor sets the minimum pitch angle of the blades, but the blades can react immediately to additional wind pressure by self feathering against the urging of the elastic linkage.
Patent NZ-562585-A (NZ)
Title: Use of slective chloride channel modulators to treat alcohol and/or stimulant substance abuse
Inventor: LEGARDA IBANEZ JUAN JOSE
IPC: A61K31/551
Filed: 2006-04-07
Abstract: Disclosed is a use of flumazenil in the preparation of a medicament for the treatment of methamphetamine abuse. Preferably the medicament provides a low dose between 1.0 to 3.0 mg/day of flumazenil. The medicament can be administered in combination with a therapeutic compound which preferably includes at least one of the following: fortified vitamin B complex, hydroxyzine, or gabapentin.
Patent NZ-576709-A (NZ)
Title: Substituted pyrazoles, compositions containing these, method of production and use
Inventor: BJERGARDE KIRSTEN
IPC: C07D231/38
Filed: 2007-11-09
Abstract: Disclosed are substituted pyrazoles of formula (I) salts and tautomers thereof, processes for their preparation and intermediates for use therein, including intermediates of the formula (VIII). The compounds inhibitor protein kinases such as KDR and Tie2 and are useful for the treatment of cancer.
Patent NZ-583416-A (NZ)
Title: Compositions and methods for treating signs of skin aging with a combination of a tropoelastin promoter and a tropoelastin crosslinker
Inventor: KIZOULIS MENAS G
IPC: A61K36/73
Filed: 2010-02-18
Abstract: Disclosed is a cosmetic composition which comprises: (a) at least one tropoelastin promoter selected from the group consisting of blackberry leaf extract, cotinus extract, feverfew extract, copper-zinc citrate, copper-zinc oxalate, copper-zinc tartarate, copper-zinc malate, copper-zinc succinate, copper-zinc malonate, copper-zinc maleate, copper-zinc aspartate, copper-zinc glutamate, copper-zinc glutarate, copper-zinc fumarate, copper-zinc glucarate, copper-zinc polyacrylic acid, copper-zinc adipate, copper-zinc pimelate, copper-zinc suberate, copper-zinc azealate, copper-zinc sebacate, copper-zinc dodecanoate and combinations thereof; (b) at least one tropoelastin crosslinker selected from the group consisting of dill extract, currant extract, cardamom extract, black radish extract, box holly extract, Asafoetida extract, ethyl hexenoate, methyl butyrate, ethyl decadienoate, and combinations thereof; and (c) a cosmetically acceptable carrier. Further disclosed is a cosmetic method of treating a sign of skin aging, which comprises topically applying to skin in need of such treatment a cosmetically effective amount of a composition as defined above.
Patent NZ-587502-A (NZ)
Title: Attenuated recombinant alphaviruses incapable of replicating in mosquitoes and uses thereof
Inventor: WEAVER SCOTT C
IPC: C12N15/33
Filed: 2009-01-23
Abstract: Disclosed is an attenuated, recombinant alphavirus comprising; an alphavirus nucleic acid, having: an inactivated subgenomic promoter; and an insertion of an internal ribosomal entry site of encephalomyelocarditis virus (EMCV IRES) between the end of nonstructural protein 4 (nsP4) coding sequence and initiating AUG of a subgenomic RNA coding sequence of the alphavirus, wherein the alphavirus is attenuated.
Patent NZ-590291-A (NZ)
Title: Pharmaceutical compositions for treatment of parkinson's disease
Inventor: SELA YORAM
IPC: A61K31/135
Filed: 2009-06-07
Abstract: 590291 Disclosed is the use of a fixed dose combination of pramipexole and rasagiline, in the manufacture of a medicament for the treatment of Parkinson's disease, wherein said fixed dose combination contains from 0.01 mg to 1.5 mg pramipexole and from 0.01 mg to 1.0 mg rasagiline. Further disclosed is the use as defined above, wherein the medicament is in the form of a tablet, a capsule, a sachet, an orally disintegrating film, a wafer, or a long lasting injectable system, and preferably in the form of microencapsulated pramipexole and rasagiline filled into a capsule.
Patent NZ-592376-A (NZ)
Title: Pharmaceutical compositions containing diacerein
Inventor: GAO DANCHEN
IPC: A61K31/715
Filed: 2009-10-28
Abstract: A once-daily controlled-release formulation of diacerein for treating inflammatory diseases, autoimmune diseases or their complications with reduced adverse side effects, comprising an active layer, a sustained-release film layer, and a delayed-release film layer, wherein said sustained-release film layer comprises an ethyl cellulose polymer, povidone, triethyl citrate and talc, and wherein said delayed-release film layer comprises a meth acrylic acid - methyl methacrylate copolymer or a methacrylic acid - ethyl acrylate copolymer, triethyl citrate and talcand methods of treating such diseases are disclosed.