baber/WOPTO huggingface dataset:
Patent CA-2306837-C (CA)
Title: Treatment of female sexual dysfunction
Inventor: PLACE VIRGIL A
IPC: A61K9/02
Filed: 1998-10-28
Granted: 2007-05-08
Abstract: Methods and formulations for treating female sexual dysfunction are provided.  A  pharmaceutical composition formulated so as to contain a selected vasoactive agent is administered to the vagina, vulvar area or urethra of the individual undergoing treatment.  Suitable vasoactive agents are vasodilators, including endothelial-derived relaxation factors, vasoactive intestinal polypeptide agonists, smooth muscle relaxants, leukotriene inhibitors, and others. The formulations are also useful for preventing the occurrence of yeast infections, improving vaginal muscle tone and tissue health, enhancing vaginal lubrication, and minimizing excess collagen deposition. A clitoral drug delivery device is also provided.
Patent CA-2309566-C (CA)
Title: Clutch arm centering device
Inventor: DIMOPOULOS WILLIAM
IPC: F16D23/12
Filed: 2000-05-25
Granted: 2007-08-21
Abstract: A clutch arm centering device is disclosed. The device is mounted on a clutch using to operate piston valves on a crane or other heavy machine. The piston valves may be operated using a valve arm which has two operative positions and a neutral position between the two operative positions. A clutch arm of the clutch is linked to valve arm to allow the valve arm to be manipulated by a remote control coupled to the clutch. As parts of the linkage between the clutch arm and the valve arm wear, the centering device biases the clutch arm to a central position which corresponds to the neutral position of the valve arm, thereby avoiding problems of understroking and overstroking which arise in the prior art. One embodiment of the centering device employs a linear spring to ensure that the clutch arm does not sag due to gravity when the linkage wears. A second embodiment employs a helical spring which actively biases the clutch arm to its central position from two opposing directions. The second embodiment is suitable for use with a clutch mounted in any orientation.
Patent CA-2311660-C (CA)
Inventor: GRAHAM RICHARD
IPC: A61L12/14
Filed: 1998-11-24
Granted: 2008-07-08
Abstract: Multi-purpose solutions for contact lens care provide substantial lens wearer/user comfort and/or acceptability. Such solutions include an aqueous liquid medium; an antimicrobial component, preferably a biguanide polymer present in an amount of less than about 5 ppm; a surfactant component, preferably a poly(oxyethylene)-poly(oxypropylene) block copolymer surfactant, in an effective amount; a phosphate buffer component in an effective amount; a viscosity inducing component, preferably selected from cellulosic derivatives, in an effective amount; and a tonicity component in an effective amount. Such solutions have substantial performance, comfort and acceptability benefits, which, ultimately, lead to ocular health advantages and avoidance of problems caused by contact lens wear.
Patent CA-2317263-C (CA)
Inventor: LEMETYINEN MARKKU
IPC: B05B3/12
Filed: 2000-08-30
Granted: 2005-06-21
Abstract: A cleaning device in a paper or board machine, for cleaning a fabric therein, the fabric moving in a direction of movement. The device comprises a nozzle which directs a water shower or jet against the fabric which is to be cleaned, the nozzle including a first turning point, and wherein there is a first plane of the water shower or jet issuing from the nozzle. A plurality of water conduits which transport water to the nozzle. And, the nozzle being mounted so that the position thereof may be changed by turning the nozzle back and forth around the first turning point in the first plane, so as to change the direction of the water shower or jet discharged from the nozzle and so that the water shower is moved in a first linear movement.
Patent CA-2322739-C (CA)
Title: Distributeur de savon pour savon a differente viscosite
Inventor: STRICKLER JEFFREY E
IPC: A47K5/12
Filed: 2000-10-10
Granted: 2003-12-30
Abstract: Système de distribution de liquides visqueux, incluant une plaque de montage et un réservoir et un mécanisme de distribution à utiliser avec une bouteille contenant un liquide ayant une viscosité allant jusqu'à environ 20 000 cps. La plaque de montage comprend une surface rectangulaire généralement plate avec des première et deuxième paires de rails de montage en extension verticale s'étendant vers l'extérieur depuis la plaque. Une première étagère est positionnée généralement horizontalement et s'étend depuis la plaque sous et entre la première paire de rails. Une deuxième étagère est positionnée généralement horizontalement et s'étend vers l'extérieur de la plaque généralement sous et entre la deuxième paire de rails. Un premier loquet flexible est positionné entre la première étagère et la deuxième paire de rails, et un mécanisme sous la deuxième étagère est destiné à supporter le mécanisme de distribution de liquide. Une bouteille comprend un goulot avec une membrane capable d'être percée, et un organe en queue d'aronde s'étendant longitudinalement à la bouteille espacé pour glisser entre au moins l'une des première et deuxième paires de rails de montage. Le réservoir comprend un logement avec une extrémité destinée à recevoir la bouteille de liquide et une ouverture à l'autre extrémité par laquelle le liquide s'écoule, et le logement comprend un poinçon s'étendant vers le haut et positionné pour s'étendre dans le goulot de bouteille et pour percer la membrane. Le réservoir et des variations de la plaque sont divulgués, tout comme des variations de bouteilles et un mécanisme de pompage différent.
Patent CA-2323681-C (CA)
Title: Development of human monoclonal antibodies and uses thereof
Inventor: TRAKHT ILYA
IPC: C07K16/28
Filed: 1999-03-18
Granted: 2012-09-25
Abstract: A trioma cell is provided which does not produce any antibody obtained by fusing a heteromyeloma cell which does not produce any antibody with a human lymphoid cell, wherein the heteromyeloma cell is the cell designated B6B11, ATCC accession number HB-12481. Methods of generating a trioma cell, and of producing a monoclonal antibody using a trioma cell are also provided.
Patent CA-2329653-C (CA)
Inventor: NAKAMURA HIROMU
IPC: F01L1/053
Filed: 2000-12-27
Granted: 2005-05-17
Abstract: In a valve operating system in an internal combustion engine, one of adjacent rocker arms is provided with first and second support walls with the second support wall disposed on the side of the other rocker arm, anal a roller is disposed between the first and second support walls to come into rolling contact with cams. A cylindrical roller shaft, on which the roller is rotatably supported, is provided between the first and second support walls, so that a switchover pin of an associative- operation switchover means can be slidably fitted into the roller shaft in response to the movement thereof to an associatively operating position. The roller shaft is press-fitted into at least second one of the first and second support walls, and a press-fit margin for the roller shaft press-fitted into the second support wall on the side of the Other rocker arm is set smaller than a press-fit margin for the roller shaft press-fitted into the second support wall on the side of the roller. Thus, the roller shaft supporting the roller and guiding the switchover pin can be fixed easily to the rocker arm, while avoiding an increase in number of parts and an increase in number of processing steps. Moreover, during movement of the switchover pins to the associatively operating position, the deformation of an end ofthe roller shaft receiving the switchover pin due to the press-fitting is suppressed to a small level, thereby smoothening the press- 35 fitting of the switchover pin into the roller shaft to smoothen the associative operation of the adjacent rocker arms and the releasing of the associative operation by the switchover pin.
Patent CA-2330683-C (CA)
Title: Body-attachable interlabial articles and methods for making the same
Inventor: LICHSTEIN BERNARD M
IPC: A61F13/472
Filed: 1999-12-07
Granted: 2008-05-27
Abstract: The present invention relates to an absorbent interlabial article containing attachment means on its body-facing surface, to allow the article to be releasably attached directly to a user's body. The interlabial article stays in place and is not inadvertently dislodged, while remaining atraumatic to wear and remove.
Patent CA-2331228-C (CA)
Inventor: HUANG YING
IPC: G10L19/005
Filed: 2001-01-17
Granted: 2004-04-06
Abstract: An insertion-based error concealment method and apparatus are provided whereby, instead of directly inserting white noise, a filter is created to shape the white noise. The filtered white noise is then used to replace lost data. The method of the present invention is implemented by first estimating the power spectrum of the previous frame; then designing a filter with transfer function H(f), where ~H(f)2=the estimated power spectrum;  and finally generating the replacement packet using noise which has been spectrally modified by the filter. The resulting filtered noise has, the same power spectrum as the previous packet but is not highly correlated with it.
Patent CA-2342991-C (CA)
Title: Antithrombogenic surfaces comprising immobilized heparin and methods for producing same
Inventor: SCHOLANDER ELISABETH
IPC: C08B37/00
Filed: 1999-09-08
Granted: 2009-01-27
Abstract: The present invention relates to a process for preparing surface modificatio ns having an improved antithrombogenic activity, whereby the improvement is achieved by treating heparin at elevated temperature or a t elevated pH or in contact with nucleophilic catalysts such as amines, alcohols, thiols or immobilized amino, hydroxyl or thiol groups befo re attaching said heparin to the surface to be modified.
Patent CA-2350500-C (CA)
Title: Dispensing method and device
Inventor: HOLSTON SYLVESTER III
IPC: B65B1/04
Filed: 1999-11-12
Granted: 2008-01-15
Abstract: A device for dispensing a product solution includes a container (23) for a product solution, the container (23) having a top end (53) including a first opening, a continuous septum (37) extending over the first opening, and a second opening, a microporous, hydrophobic membrane extending across the second opening.
Patent CA-2369508-C (CA)
Inventor: IRII KIYOTAKA
IPC: B60S5/00
Filed: 2002-01-28
Granted: 2007-04-17
Abstract: An automobile sheet metal surface correcting equipment capable of permitting alignment between a piston of the equipment and a portion of the sheet metal surface to be corrected to be carried out from an inside of the sheet metal such as a bonnet, to thereby facilitate sheet metal working. The equipment includes a housing having an air flow path switchably arranged therein, an air introduction structure provided therein with air introduction passages for introducing compressed air into the housing therethrough, an impact wrench mechanism arranged in the housing and actuated by compressed air fed through the air introduction structure into the housing, a screw bolt having rotating force applied thereto from the impact wrench mechanism, and a piston mechanism including a cylinder and a piston movably arranged in the cylinder in a retractable manner in association with rotation of the screw bolt; so that the air flow path in the housing is changed over to retractably move the piston of the piston mechanism, resulting in correcting a metal sheet surface.
Patent CA-2379533-C (CA)
Inventor: VOGELGESANG CLAUS-JOSEPH
IPC: A01D43/08
Filed: 2002-03-28
Granted: 2006-05-30
Abstract: The invention pertains to a rolling element bearing for a product conveyor and/or product processing element of a harvesting machine, with the bearing including a rolling element chamber and an antechamber, that protects the railing elements from the penetration of plant juices. A first lubricant feed is provided for supplying lubricant to the roiling elements and a separate second lubricant feed is provided for supplying lubricant to the antechamber.
Patent CA-2386234-C (CA)
Inventor: SAT GIL
IPC: G04F13/00
Filed: 2000-10-12
Granted: 2009-06-02
Abstract: The present invention provides a cap (12) for a hermetically sealed container (11), said cap providing a visually observable indication of elapsed time from the opening of the seal of said container, said cap including means for releasing a chemical which effects a color change in a chamber formed therein, said chamber being provided with a transparent section (14) for viewing the contents thereof and said released chemical effecting a cumulative color change of said section (16) with time, the arrangement being such that manipulation of said cap to open said container and said seal effects activation of said releasing means.
Patent CA-2393050-C (CA)
Title: Inhibition of polymerization of unsaturated monomers
Inventor: FABIAN JESUS
IPC: C07B63/04
Filed: 2000-11-28
Granted: 2009-11-17
Abstract: Disclosed herein is a method for inhibiting the premature polymerization of ethylenically unsaturated monomers comprising adding to said monomers an effective amount of a mixture comprisi ng at least two different inhibitors having structural formula ((I). In this formula, R1 and R4 are independently selected from the group consisting of hydrogen, alkyl, and heteroatom-substituted alkyl and R2 and R3 are independently selected from t he group consisting of alkyl and heteroatom-substituted alkyl; and X1 and X2 (1) are independently selected from the group consisting of haloge n, cyano, COOR11 (wherein R11 is alkyl or aryl) amido, -S-C6H5, -S-COCH3, -OCOC2H5, carbonyl, alkenyl (where the double bond is not conjugated with the nitroxide moiety), or alkyl of 1 to 15 carbon atoms, or (2) taken together, form a ring structure with the nitrogen.
Patent CA-2393749-C (CA)
Inventor: LACOMBE PATRICK
IPC: A61P11/00
Filed: 2000-12-20
Granted: 2008-06-17
Abstract: La présente invention concerne de nouvelles 8-arylquinolines substituées représentées par la formule (I) ou un sel pharmaceutiquement acceptable de ces dernières. Dans la formule (I), S1, S2 et S3 représentent indépendamment H, -OH, halogène, -C1-C6alkyle, -NO2, -CN, ou -C1-C6alcoxy, les groupes alkyle et alcoxy étant facultativement substitués par 1 à 5 substituants; chaque substituant étant lui-même un halogène ou OH; R1 représente H, OH, halogène, carbonyle, ou -C1-C6alkyle, -cycloC3-C6alkyle, -C1-C6alcényle, -C1-C6alcoxy, aryle, hétéroaryle, -CN, -hétérocycloC3-C6alkyle, -amino, -C1-C6alkylalmino, -(C1-C6alkyle)(C1-C6alkyle)amino, -C1-C6alkyl(oxy)C1-C6alkyle, -C(O)NH(aryle), -C(O)NH(hétéroaryle), -SOnNH(aryle), -SOnNH(hétéroaryle), -SOnNH(C1-C6alkyle), -C(O)N(C0-C6alkyle), (CO-C6alkyle),-NH-SOn-(C1-C6alkyle), -SOn-(C1-C6alkyle), -(C1-C6alkyle)-O-C(CN)-dialkylamino, ou un groupe -(C1-C6alkyl)-SOn-(C1-C6alkyle), chaque groupe pouvant être facultativement substitué par 1 à 5 susbtituants; chaque substituant représentant indépendamment halogène, -OH, -CN, -C1-C6alkyle, -cycloC3-C6alkyle, -C(O)(hétérocycloC3-C6alkyle), -C(O)-O-(C0-C6alkyle), -C(O)-aryloxy, -C1-C6alcoxy, -(C0-C6alkyle)(C0-C6alkyle)amino, cycloalkyloxy, acyle, acyloxy, -cycloC3-C6alkyle, hétérocycloC3-C6alkyle, aryle, hétéroaryle, carbonyle, carbamoyle, ou -SOn-(C1-C6alkyle); A représente CH, C-ester, ou C-R4; R2 et R3 représentent indépendamment aryle, hétéroaryle, H, halogène, -CN, -C1-C6alkyle, hétérocycloC3-C6alkyle, -C1-C6alcoxy, carbonyle, carbamoyle, -C(O)OH, -C1-C6alkyle)-SOn-(C1-C6alkyle), -C(O)N(C0-C6alkyle)(C0-C6alkyle), ou un groupe -C1-C6alkylacylamino, chaque groupe étant facultativement substitué par 1 à 5 substituants et chaque substituant étant indépendamment aryle, hétéroaryle, halogène, -NO2, -C(O)OH, carbonyle, -CN, -C1-C6alkyle, -SOn-(C1-C6alkyle), -SOn-(aryle), aryloxy, -hétéroaryloxy, C1-C6alcoxy, N-oxyde, -C(O)-hétérocycloC3-C6alkyle, -NH-cycloC3-C6alkyle, amino, -OH, ou -(C0-C6alkyle)(C0-C6alkyle)amino, groupe substituant -C(O)-N(C0-C6alkyle)(C0-C6alkyle), chaque groupe substituant étant facultativement substitué par -OH, C1-C6alcoxy, -C1-C6alkyle, -cycloC3-C6alkyle, aryloxy, -C(O)OH, -C(O)O(C1-C6alkyle), halogène, -NO2, -CN, -SOn-(C1-C6alkyle), ou -C(O)-N(C0-C6alkyle)(C0-C6alkyle); R2 ou R3 doit obligatoirement représenter aryle ou hétéroaryle, facultativement substitué; lorsque R2 et R3 représentent tous les deux aryle ou hétéroaryle, alors R2 et R3 peuvent être facultativement reliés par un pont thio, oxy, ou (C1-C4alkyle) pour former un système à trois cycles fusionnés. Ces composés sont des inhibiteurs de PDE4.
Patent CA-2395204-C (CA)
Title: Piperidinyloxy and pyrrolidinyloxyphenyl oxazolidinones as antibacterials
Inventor: BOGGS CHRISTINE
IPC: A61P19/02
Filed: 2000-12-14
Granted: 2008-02-05
Abstract: Piperidinyloxy, pyrrolidinyloxyl and azetidinyloxy compounds of the formula (I): wherein R1 is a piperidinyl, pyrrolidinyl or azetidinyl moiety as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
Patent CA-2395769-C (CA)
Inventor: MASSARO VINCENT PAUL
IPC: H04B1/04
Filed: 2002-07-25
Granted: 2010-12-07
Abstract: Méthode pour processeur et support lisible sur un processeur permettant de réduire le niveau de parasites de contre-réaction dans le signal de sortie d'un circuit de commande automatique de gain. La méthode permet de recevoir un train d'impulsions comprenant un signal d'entrée dans le circuit de commande automatique de gain. La méthode permet en outre de recevoir des estimations des composants énergétiques respectifs haute et basse fréquence du signal d'entrée. Les composants respectifs haute et basse fréquence sont calculés en moyenne, par exemple, sur une fenêtre coulissante concernée. Un scalaire énergétique est fondé sur le ratio d'un niveau d'énergie cible prédéfini sur une valeur combinée des composants de fréquence haute et basse. Une action associée permet de comparer le niveau énergétique cible avec la valeur combinée des composants de fréquence haute et basse. En fonction des résultats de la comparaison, le scalaire énergétique calculé est limité à une valeur comprise entre les deux valeurs limites. Une action associée ultérieure permet de comparer entre elles les valeurs des moyennes des composants de fréquence haute et basse. Si la valeur de la moyenne de fréquence haute dépasse celle de la moyenne de fréquence basse, le scalaire énergétique est réduit à une valeur suffisamment basse pour supprimer les parasites de contre-réaction dans le signal d'entrée du circuit et générer un signal de sortie associé à un faible niveau de parasites de contre-réaction. Si la valeur de la moyenne de fréquence basse dépasse la valeur de la moyenne de fréquence haute, le scalaire énergétique est appliqué au signal en entrée pour générer un signal de sortie dimensionné dans la limite des deux valeurs limites.
Patent CA-2399750-C (CA)
Inventor: BENHAMMOU DAVID
IPC: G07C9/00
Filed: 2000-12-07
Granted: 2006-06-20
Abstract: The invention concerns a reader for electronic keys comprising a protective metal housing, characterised in that it has, at least, a slot (5) extending from one of its edges to the centre of its front surface (2).
Patent CA-2400559-C (CA)
Title: Humanized antibodies that sequester .alpha..beta. peptide
Inventor: HOLTZMAN DAVID M
IPC: A61K39/00
Filed: 2001-02-26
Granted: 2012-05-01
Abstract: A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble A.beta. peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide A.beta..
Patent CA-2402408-C (CA)
Inventor: SERAJ JILA
IPC: H04W68/00
Filed: 2000-12-14
Granted: 2005-09-27
Abstract: A method of defining a location are within the service area of a wireless network utilizes paging traffic and handoff traffic statistics. Initially, a cell having the highest volume of paging traffic is identified and marked as belonging to a working location area.      The cell having the highest volume of handoff traffic with the cell in the working location area is selected and a determination is made to determine if the combined paging traffic of the first and second cells exceeds the maximum paging capacity for a location area within the service area. If the maximum paging capacity has not been exceeded, then the second cell is added to the working location area. The process continues until all cells, except for the occasional dead cell, have been allocated to a location area.
Patent CA-2403456-C (CA)
Inventor: LITTLER WILLIAM IV
IPC: A01G25/16
Filed: 2002-09-16
Granted: 2005-01-04
Abstract: The tile flow regulator disclosed is used for regulating the level of water in the fields of an agricultural operation according to seasonal needs by a mechanism for adjusting the outflow of water from the tile line. The regulator includes a housing through which water from the tile line is directed and in which a partition with at least one aperture is positioned. At least one vertically movable gate is associated each aperture and with a motor and gear assembly such that, upon actuation of the motor by a 12-month calendar, said gates) move to either open or close the aperture. If two apertures are included, the regulator can be fully open (both apertures open), fully closed (both apertures closed), or partially open (bottom aperture open, top one closed) to achieve the desired moisture level.
Patent CA-2405704-C (CA)
Title: Bombesin analogs for treatment of cancer
Inventor: BURMAN ANAND C
IPC: A61K38/10
Filed: 2000-07-31
Granted: 2010-11-16
Abstract: The present invention encompasses novel peptides that are antagonists to bombesin and bombesin like peptides and are useful in the treatment of cancer. The invention particularly relates to the design and synthesis of the novel peptides incorporating .alpha.,.alpha.-amino acids in a site specific manner. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.
Patent CA-2422081-C (CA)
Inventor: DAVIS BRUCE L
IPC: G06Q30/00
Filed: 2001-10-25
Granted: 2007-08-21
Abstract: Selon l'invention, des articles physiques peuvent être filigranés numériquement, d'où la possibilité de les reconnaître au moyen de caméras Web, par exemple, en vue de déclencher des actions correspondantes. Des tasses à café et des couvercles pour tasses à café constituent des exemples d'articles pouvant être filigranés de la sorte. L'action déclenchée par reconnaissance de l'article peut varier selon l'environnement dans lequel la reconnaissance a eu lieu (magasin ou bureau, par exemple). De même, cette action peut varier avec le temps (déclenchement d'une première réponse lors d'une première présentation et déclenchement d'une seconde réponse différente lors d'une seconde présentation, par exemple). Certains de ces articles peuvent comporter plusieurs faces (deux pour une carte de crédit, six pour un carton, etc.), chacune de ces faces étant codée par un filigrane différent et déclenchant une réponse différente.