baber/WOPTO huggingface dataset:
Patent JP-2021079001-A (JP)
Title: Outsole and footwear
Inventor: SHO KAZUMI
IPC: A43B13/14
Filed: 2019-11-22
Abstract: To provide an outsole that makes a barycentric position easy to identify and that supports stable walking.SOLUTION: An outsole includes an outsole plate body that is extended from a forefoot region of a wearer's foot to a heel region thereof, and first, second and third protrusions that are provided on the heel region of the bottom surface of the outsole plate body. The first protrusion is arranged on the inner instep side of the heel region; the second protrusion is arranged on the outer instep side of the heel region; and the third protrusion is arranged near the center of the heel region.SELECTED DRAWING: Figure 1
Patent JP-2021087042-A (JP)
Title: Imaging apparatus and camera
Inventor: TOKUNAGA YUSUKE
IPC: H04N5/378
Filed: 2019-11-26
Abstract: To provide an imaging apparatus capable of reducing variations of an AD conversion gain.SOLUTION: An imaging apparatus 1 comprises: an image pixel array 100 in which a plurality of image pixels is arranged in a two-dimension; a first conversion circuit 10 that converts an analog signal from a pixel of a first group into a digital signal; a second conversion circuit 20 that is arranged at a position separated from the first conversion circuit 10, and converts the analog signal from the pixel from a second group into the digital signal; a first lamp signal generation circuit 30 that is arranged at a position near to the first conversion circuit 10 from the second conversion circuit 20, and supplies the first lamp signal to the first conversion circuit 10 and the second conversion circuit 20; a first connection line in which one end is connected to an output terminal 31 of the first lamp signal generation circuit 30, and which contains a part extended far from an input terminal 11 of the first conversion circuit 10 toward the other terminal from the one end; and a second connection line in which the one end is connected to the other end of the first connection line, the other end is connected to the input terminal 11, and which contains the part extended so as to approach the input terminal 11 toward the other end from the one end.SELECTED DRAWING: Figure 5
Patent JP-2020053981-A (JP)
Title: Device control apparatus and device control method
Inventor: OKAMOTO TOSHIYUKI
IPC: H04Q9/00
Filed: 2019-11-27
Abstract: To provide a device control apparatus and device control method for controlling various kinds of devices with the use of one application software.SOLUTION: A device control apparatus connected to portable communication terminals 2a, 2b and multiple devices 3a-3c via a network includes: an acquisition section for acquiring first control information being the information, that is to be generated by execution of application software for controlling a specified kind of device installed in the portable communication terminal, includes identification information for identifying a control object device selected from the multiple devices, and is used for controlling a specified kind of device, from the portable communication terminal via the Internet; a generation section for generating second control information to allow a control object device identified based on identification information to perform control contents indicated by the first control information on the basis of the first control information; and a transmission section for transmitting the second control information via the Internet.SELECTED DRAWING: Figure 1
Patent JP-2020095265-A (JP)
Title: Light-shielding member and imaging device using the light-shielding member
Inventor: SATO YASUHIRO
IPC: G02B5/00
Filed: 2019-11-27
Abstract: To provide a light-shielding member excellent in environmental stability by the composition of a light-absorbing layer.SOLUTION: A light-shielding member 10 includes an optical attenuation film 5 having alternately stacked dielectric layers 2 and light-absorbing layer 3 on a light-shielding substrate 1 having an opening formed therein. The optical attenuation film has a plurality of light-absorbing layers; and the plurality of light-absorbing layers are constituted by a first light-absorbing layer made of a metal compound and a second light-absorbing layer made of a metal compound disposed at a position farther from the light-shielding substrate than the first light-absorbing layer in a stacking direction of the layers, in which an oxidation number of the metal in the second light-absorbing layer is greater than an oxidation number of the metal in the first light-absorbing layer. A dielectric layer may be disposed between the light-shielding substrate and the optical attenuation film. The light-absorbing layer may be sandwiched between a plurality of dielectric layers. The imaging device may include the light-shielding member and an image sensor for imaging the light that has passed through the opening of the light-shielding member.SELECTED DRAWING: Figure 1
Patent JP-2021088075-A (JP)
Title: Method for producing printing device and printing device
Inventor: KOBAYASHI SAORI
IPC: B41J2/01
Filed: 2019-12-03
Abstract: To provide a technique for efficiently printing an adjustment pattern.SOLUTION: A method for producing a printing device that can perform printing while varying adjustment amounts for an object to be adjusted performs: a step of printing a first adjustment pattern on a printing medium using the different adjustment amounts; a step of obtaining a first adjustment amount by reading out the printed first adjustment pattern; a step of printing on the printing medium a second adjustment pattern corresponding only to some adjustment amounts corresponding to the first adjustment amount, of second adjustment patterns printed using the different adjustment amounts; a step of obtaining a second adjustment amount by reading out the printed second adjustment pattern; a step of setting a first parameter, an adjusted result of the object to be adjusted using the first adjustment amount; and a step of setting a second parameter, an adjusted result of the object to be adjusted using the second adjustment amount.SELECTED DRAWING: Figure 1
Patent JP-2021090154-A (JP)
Title: Image processing device and computer program for terminal device
Inventor: MATSUDA MUNEHISA
IPC: H04W84/10
Filed: 2019-12-04
Abstract: To provide techniques for improving user convenience.SOLUTION: An image processing device transmits an advertising signal including prescribed information via a first radio interface. When the advertising signal including the prescribed information is received by a first terminal device, the image processing device receives first connection information from the first terminal device and establishes a first radio connection with a first access point using the first connection information. And then the image processing device performs a relationship processing related to image processing. The relationship processing includes performing communication of target data related to the image processing with the first terminal device via the first access point. The image processing device forbids processing for establishing a radio connection with a different access point while performing the communication of the target data with the first terminal device.SELECTED DRAWING: Figure 3
Patent JP-2020036047-A (JP)
Title: SiC semiconductor device
Inventor: UENO MAYA
IPC: H01L29/868
Filed: 2019-12-06
Abstract: To provide an SiC semiconductor device capable of suppressing wet spreading of a conductive joining material in an SiC semiconductor layer including a side surface having a rough surface region.SOLUTION: An SiC semiconductor device 1 includes: an SiC semiconductor layer 2 having a laminate structure including an SiC semiconductor substrate 6 and an SiC epitaxial layer 7, and including an element formation surface composed of the SiC epitaxial layer 7; rough surface regions 20A to 20D formed in a portion composed of the SiC semiconductor substrate 6 in side surfaces 5A to 5D of the SiC semiconductor layer 2 and exposing the SiC epitaxial layer 7; and smooth surface regions 21A to 21D formed in a portion composed of the SiC epitaxial layer 7 in the side surfaces 5A to 5D of the SiC semiconductor layer 2.SELECTED DRAWING: Figure 3
Patent JP-2021091795-A (JP)
Title: Composition and polymer molding
Inventor: HOTTA FUMI
IPC: C08K5/13
Filed: 2019-12-10
Abstract: To provide a polymer molding having excellent breaking strength, and a composition for obtaining a polymer molding that has excellent breaking strength and suppresses the gelation of a copolymer when mixing.SOLUTION: A composition comprises a polymer component comprising a copolymer that has a conjugated diene unit and a non-conjugated olefin unit, and a compound (A) that has a 1% mass loss temperature of 200°C or higher when heated at 20°C/min under a nitrogen atmosphere.SELECTED DRAWING: None
Patent JP-2021080020-A (JP)
Title: Printing device for canned dairy products
Inventor: YU LIANG
IPC: B41K3/36
Filed: 2019-12-13
Abstract: To provide a printing device for canned dairy products.SOLUTION: In the printing device for canned dairy products including a main body, a first rotation space is disposed in the main body, and a motor is disposed in a rear end wall of the first rotation space; a first rotary shaft connected to the motor so as to be transmittable with the motor is connected to a front wall end of the first rotation space so as to be rotatable; a first gear is fixed on a surface of the first rotary shaft; a first rack is meshed with a left side of the first gear, and a second rack is meshed with a right side of the first gear; a first slide space is provided at a lower end of the first rotation space, and a printing mechanism is disposed in the first slide space; and a second slide space is provided at a left side of the first rotation space.SELECTED DRAWING: Figure 1
Patent JP-2021095009-A (JP)
Title: Sealant material composition
Inventor: TAKAHASHI KIYOTO
IPC: B60C19/12
Filed: 2019-12-17
Abstract: To provide a sealant material composition that makes it possible to prevent the flow of a sealant caused by driving, while maintaining satisfactory sealability.SOLUTION: A sealant material composition forms a sealant layer 10 disposed on the inner surface of a pneumatic tire. The composition has a tensile stress at 20% elongation of 0.03 MPa or less at 23°C, and a tensile stress at 20% elongation of 0.002 MPa or more at 80°C.SELECTED DRAWING: Figure 1
Patent JP-2020063282-A (JP)
Title: Antibodies for treatment of cancer
Inventor: SAHIN UGUR
IPC: C07K16/30
Filed: 2019-12-19
Abstract: To provide antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDN6, including tumor-related diseases such as ovarian cancer, lung cancer, gastric cancer, breast cancer, hepatic cancer, pancreatic cancer, skin cancer, malignant melanoma, head and neck cancer, sarcoma, bile duct cancer, cancer of the urinary bladder, kidney cancer, colon cancer, placental choriocarcinoma, cervical cancer, testicular cancer, and uterine cancer.SOLUTION: An antibody is capable of binding to CLDN6 associated with the surface of a cell that expresses CLDN6 and is not substantially capable of binding to CLDN9 associated with the surface of a cell that expresses CLDN9.SELECTED DRAWING: None
Patent JP-2021095069-A (JP)
Title: Vehicular braking device
Inventor: MITSUKA RYUSUKE
IPC: B60T17/04
Filed: 2019-12-19
Abstract: To provide a vehicular braking device capable of securing reliability of brake piping in a vehicle adopting a beam type De Dion axle.SOLUTION: A vehicle with a De Dion axle includes: a drive shaft coupled to a wheel 8; a hollow member 41 accommodating a part of the drive shaft in an inner space thereof; a beam member coupling the hollow member 41, the beam member including a connection surface 35 connected to the hollow member 41, a back surface 36 opposed to the connection surface 35 and a coupling surface 37 continuing the connection surface 35 and the back surface 36 and opposed to the wheel; a braking mechanism 60 generating braking force in the wheel 8; and brake piping 70 transmitting hydraulic pressure generated through a brake pedal operation to the braking mechanism 60. The brake piping 70 includes: an L-shaped rigid pipe 72 continuously extending from the back surface 36 to the coupling surface 37 of the beam member; and a flexible hose 73 having one end connected to the L-shaped rigid pipe 72 and the other end connected to the braking mechanism.SELECTED DRAWING: Figure 3
Patent JP-2021097785-A (JP)
Title: Game machine
Inventor: IGAWA TAKAHIRO
IPC: A63F7/02
Filed: 2019-12-20
Abstract: To provide a game machine capable of enhancing interest in a game.SOLUTION: In a case having a time-shortening limiter function, the number of balls acquired by a player is still less than 7,200 and "latent probability variation state" is underway in a stage when one hour passes after entering a "consecutive" state, and further a possibility of requiring approximately 17 minutes or longer until a next jackpot is acquired after entering the "latent probability variation state" is set to become high. Accordingly, it becomes possible to more gradually increase the number of balls acquired in a short time of approximately 1 hour by the player than a Pachinko machine without any time-shortening limiter functions, thus preventing the number of balls acquired by the player per hour from becoming excessive. As a result, a player's speculative spirit cannot be aroused excessively, thus providing a Pachinko machine 10 allowing the player to appropriately play a game.SELECTED DRAWING: Figure 28
Patent JP-2021103087-A (JP)
Title: Motion sensor selection device, target detection system and motion sensor selection method
Inventor: MURATA WATARU
IPC: G01S15/06
Filed: 2019-12-24
Abstract: To build a motion sensor selection model in a short time by machine learning, and to realize early start of operation.SOLUTION: A motion sensor selection device includes an input unit, a motion sensor selection model, and a motion sensor selection unit. The input unit accepts input of input information for at least one target that includes a target state quantity for at least one of position, course, and speed with respect to each of targets. The motion sensor selection model is the one in which machine learning is performed to select at least one sensor to be selected from a plurality of sensors from base information including the target state quantity of the one target over a time span. The motion sensor selection unit decomposes the input information about multiple targets entered in the input unit into information related to the one target, inputs each of the decomposed information into the motion sensor selection model and integrates a plurality of the output selection results, and selects a sensor to operate as the motion sensor.SELECTED DRAWING: Figure 4
Patent JP-2021102532-A (JP)
Title: Plant for producing ammonia derivative and method for producing ammonia derivative
Inventor: TSUJIUCHI TATSUYA
IPC: C01C1/02
Filed: 2019-12-25
Abstract: To provide a plant for producing an ammonia derivative in which the production cost of the ammonia derivative is reduced, and to provide a method for producing the ammonia derivative.SOLUTION: A plant for producing an ammonia derivative comprises an electrolysis apparatus for electrolyzing water, an ammonia synthesis apparatus for synthesizing ammonia from hydrogen and nitrogen generated in the electrolysis apparatus, a carbon dioxide generation apparatus for generating carbon dioxide, and an ammonia derivative synthesis apparatus for synthesizing an ammonia derivative from ammonia synthesized in the ammonia synthesis apparatus and carbon dioxide generated in the carbon dioxide generation apparatus. Oxygen generated in the electrolysis apparatus is consumed for generating carbon dioxide in the carbon dioxide generation apparatus.SELECTED DRAWING: Figure 1
Patent JP-2021102389-A (JP)
Title: Panel device
Inventor: NAGASE MIRAI
IPC: B60H1/34
Filed: 2019-12-25
Abstract: To provide a panel device that can be improved in design property.SOLUTION: A panel device 1 includes multiple panels 3 which are inclined so as to be opened and closed by rotating about the shafts thereof. The panel device 1 includes an interlock mechanism 20 for interlocking the multiple panels 3 with each other so that the multiple panels 3 are flush with each other when the multiple panels 3 are closed and the opening degrees of those panels are brought into multiple combinations when opening the multiple panels 3.SELECTED DRAWING: Figure 1
Patent JP-2021103473-A (JP)
Title: Device for predicting required printing time
Inventor: NAKADAI AYA
IPC: G03G21/00
Filed: 2019-12-25
Abstract: To provide a device for predicting required printing time capable of predicting required printing time for a plurality of printing devices with high accuracy.SOLUTION: A device for predicting required printing time comprises: a correction value calculation unit 22 for calculating a common correction value based on a plurality of correction values calculated when a plurality of print jobs with the same print setting condition are processed by each printing device; and a predicted required printing time calculation unit 24 for calculating predicted required printing time for a new print job based on the common correction value and outputting it to a printing device other than a printing device corresponding to a unique correction value, and calculating predicted required printing time for the new print job based on the unique correction value and outputting it to the printing device corresponding to the unique correction value, wherein a correction value that differs from the common correction value by a value that is more than or equal to a threshold value set in advance is defined to be the unique correction value for the printer that processed a print job in which the correction value was calculated.SELECTED DRAWING: Figure 1
Patent JP-2020079698-A (JP)
Title: Cooling galley with dry ice
Inventor: BRYCE A VANDYKE
IPC: F25D3/14
Filed: 2019-12-27
Abstract: To provide: structurally simple and cost effective metering and venting systems for COsublimates in galley carts; and effective mating systems for galley carts with on board galleys for efficient external venting of CO.SOLUTION: The invention employs a galley cart system having a dry ice compartment 22 and a refrigeration compartment 28 in a galley cart in flow communication with the dry ice compartment 22. A ventilation system is in interruptible flow communication with at least the refrigeration compartment 28 and configured to receive gas discharged from at least the refrigeration compartment 28.SELECTED DRAWING: Figure 1A
Patent JP-2021106672-A (JP)
Title: Container with applicator
Inventor: YOSHIMURA KAZUHISA
IPC: B65D83/00
Filed: 2019-12-27
Abstract: To provide a container with an applicator, enabling adhering contents to the applicator even when contents stored in a container body are reduced, and facilitating performing operation of applying contents with the applicator.SOLUTION: A container 100 with an applicator comprises: a container body 10; a cap 20 detachably attached to a mouth part 13 of the container body 10; and an applicator 30 having an application part 33 and a shaft part 31. The container further comprises: a cap body 21 having a thread part 21c in a peripheral wall 21b, and an insertion hole 21d on a top surface 21a; an applicator length variable holding part 22 for holding the applicator 30 so as to vary an insertion depth of the shaft part 31 inserted via the insertion hole 21d; and a rubbing cylinder 23 disposed below the top surface 21a, to be inserted with the shaft part 31, and comprising a cylindrical elastic member. A bottom edge of the rubbing cylinder 23 is tightly fitted to a surface of the shaft part 31 at the lower side of the thread part 21c.SELECTED DRAWING: Figure 1
Patent JP-2019521230-A (JP)
Title: ニトリル系ゴムの製造方法
IPC: C08L9/02
Filed: 2017-12-19
Abstract: 本発明は、開始剤と、Ｃ30からＣ60であり、２個以上のカルボキシ基を有する化合物を含む乳化剤との存在下、α，β−不飽和ニトリル系単量体及び共役ジエン系単量体を含む単量体混合物を重合してニトリル系ゴムを製造するニトリル系ゴムの製造方法、これによって製造されたニトリル系ゴム、及び前記ニトリル系ゴムを含むニトリル系ゴム組成物に関する。【選択図】なし
Patent JP-2019531199-A (JP)
Title: 現場で収集された測定値に基づくカスタマイズされたロボット設置
IPC: B25J13/08
Filed: 2017-07-27
Abstract: 【課題】 操作員による中断および／または介入なしで継続することである。【解決手段】 ロボット・システム（１００）は、生産工程に従って、生産現場（２６）、たとえば川敷地または建物において、少なくとも１つの物理物体（２２）、たとえば杭またはタイル（４２）などと、物理構造（２０）、たとえば橋または壁（４７）とを組み合わせる１つまたは複数のエンドエフェクタ（２１１）を有するロボット（２００）を含む。センサ（２１２）、たとえば力、速度、ポジション、形状、光／カメラなどが、生産工程に関するセンサ・データを生成する。たとえば、生産現場（２６）のモデルは、所望の橋を建造するためにコンクリート杭および他の建設資材をどのように組み合わせることができるのかの土木技師の構想を提供することができる。制御システム（２１８）は、生産現場および／または少なくとも１つの物体のモデルに基づく生産工程の仕様書を記憶する。制御システムは、センサ・データを受け取り、生産現場または物体のうちの少なくとも１つのプロパティを判定し、プロパティとモデルとの間の相違を判定し、相違に基づいて生産工程に対する調整を決定し、エンドエフェクタに関して、仕様書および生産工程に対する調整に基づいて、物体と構造とを組み合わせる命令を送る。ロボットが独力で生産工程を調整することを可能にすることによって、生産工程は、操作員による中断および／または介入なしで継続することができる。【選択図】図２
Patent JP-2019524495-A (JP)
Title: ポリオルガノシロキサン系スタンプを製造する方法、ポリオルガノシロキサン系スタンプ、プリントプロセスへの同スタンプの使用、及び同スタンプを使用したインプリント方法
IPC: C08L83/04
Filed: 2017-07-27
Abstract: 転写パターン面を含むマスターを用意するステップ；第１の硬化性組成物の第１の層を転写パターン面に形成し、その結果、第１の層が前記転写パターンのレリーフパターンを含むステップ；第１の層を部分的に硬化するステップ；第２の硬化性組成物の第２の層を、部分的に硬化した第１の層に堆積するステップ；部分的に硬化した第１の層及び第２の層を同時に硬化して、第１のヤング率より低い第２のヤング率を有する硬化した第２の層に接着した、第１のヤング率を有する硬化した第１の層を形成するステップ；第３の硬化性組成物の第３の層を第２の層に堆積し、第３の層を硬化して、硬化した第２の層に接着した硬化した第３の層を形成するステップを有するポリオルガノシロキサン系スタンプを製造する方法が開示されている。この方法から得ることができるポリオルガノシロキサン系スタンプ；プリントプロセスのための同スタンプの使用；及び同スタンプを使用したインプリント方法が、さらに開示されている。
Patent JP-2019530367-A (JP)
Title: ビデオコーディングのための可変数のイントラモード
IPC: H04N19/136
Filed: 2017-10-04
Abstract: ビデオコーダは、ビデオデータの第1のブロックがイントラモードコーディングされると判断し、第1のブロックの第1の高さおよび第1の幅に基づいて、ビデオデータの第1のブロック用の、N個の利用可能なイントラ予測モードのグループを識別し、N個の利用可能なイントラ予測モードのグループから、ビデオデータの第1のブロックをコーディングするのに使われる第1のイントラ予測モードを選択し、第1のイントラ予測モードを使用して第1のブロックをコーディングする。ビデオコーダは、ブロック用の第1の最確モード(MPM)候補リストを生成し、ブロックをコーディングするのに使われる実際のイントラ予測モードが第1のMPM候補リスト中に含まれないことを示す第1のフラグをコーディングし、第1のMPM候補リスト中のイントラ予測モードに基づいて少なくとも1つの候補イントラ予測モードを導出することによって、第2のMPM候補リストを生成する。
Patent JP-2020501514-A (JP)
Title: 治療用ＭＯＴＳ−ｃ関連ペプチド
IPC: A61P3/06
Filed: 2017-09-27
Abstract: ペプチドおよびペプチド類似体および代謝疾患、例えば、肥満症、糖尿病の治療方法、癌の治療方法、肝疾患の治療方法、および脂肪酸代謝の調節方法が、本明細書で提供される。【選択図】なし
Patent JP-2019532610-A (JP)
Title: 電気制御システム、電気自動車、及びエネルギー蓄積装置
IPC: B60L50/64
Filed: 2017-10-05
Abstract: 複数のモードで動作可能な電気自動車の電気制御システム。制御システムは、複数のモータコイルを有する電動機と、電気制御システムにエネルギーを供給するエネルギー蓄積装置と、電動機をエネルギー蓄積装置に選択的に連結するトランジスタモジュールと、交流電源に選択的に連結するコネクタと、コネクタを電動機に選択的に連結するように構成された制御可能なスイッチング装置とを備える。マイクロコントローラは、検出された充電モードにおいてコネクタを少なくとも１つのモータコイルに結合し、検出された充電モードにおいてモータコイルをエネルギー蓄積装置に連結するように１つ又は複数のトランジスタモジュールを制御するようにスイッチング装置を制御する。【選択図】図４
Patent JP-2020500356-A (JP)
Title: 仮想コントローラのための機能割当て
IPC: A63F13/428
Filed: 2017-10-30
Abstract: 方法は、コンピュータシステムにおいて仮想コントローラを物理的なコントローラと対応付けることと、第１の機能を仮想コントローラに割当てて物理的なコントローラを用いて第１の機能の性能を提供することと、物理的なコントローラを用いて行われたジェスチャを検出することと、ジェスチャの検出に応じて、仮想コントローラから第１の機能の割当てを解除する、または、第２の機能を仮想コントローラに割当てることとを備える。
Patent JP-2020513731-A (JP)
Title: 添加剤の損失を低減するための喫煙物品用フィルタ
IPC: A24D3/06
Filed: 2017-12-08
Abstract: 本発明は、ランダムに配向された別個の繊維を含む喫煙物品に使用するためのフィルタの改良に関する。改良は、主に、前記フィルタ中の添加剤の損失および前記フィルタの製造に関する。【選択図】図１
Patent JP-2020500239-A (JP)
Title: 改善された低温耐衝撃性を有する衝突耐久性エポキシ接着剤
IPC: C09J163/00
Filed: 2017-10-06
Abstract: 一成分型エポキシ接着剤組成物は、エポキシ樹脂と、ポリウレタン系強化剤と、エポキシでキャップされたポリマー主鎖からなるエポキシキャップされた強化剤であって、ポリマー主鎖が、エポキシ樹脂に少なくとも部分的に不混和性である強化剤と、エポキシ硬化剤と、からなる。一成分型接着剤組成物は、−４０℃以下などの低温での改善された耐衝撃性を有し得る。エポキシ系強化剤は、ポリオールのヒドロキシルを化学量論的に過剰の環状無水物と反応させてカルボン酸キャップされたポリマーを形成することによって形成され得る。次いで、カルボン酸キャップされたポリマーを少なくとも２個のエポキシドを有する化学量論的に過剰のエポキシ樹脂と反応させてエポキシド末端基を有するエポキシキャップされた強化剤を形成する。
Patent JP-2020503254-A (JP)
Title: 治療活性ペイロードの標的化送達のための送達システム
IPC: A61K47/64
Filed: 2017-10-27
Abstract: 本発明は、ビオチン-ビオチン結合要素複合体形成によって排他的に組み立てられる新規標的化生物コンジュゲートであって、モノビオチン化細胞結合成分、四量体ビオチン-結合要素、並びに治療及び診断目的のためのモノビオチン化ペイロードを含む、前記生物コンジュゲートのモジュール式の設計及び組立てを提供する。さらに、抗体又はリガンドなどのモノビオチン化標的化装置を介した受容体仲介型エンドサイトーシスによって、真核生物細胞にペイロード、例えば治療用オリゴヌクレオチドを送達する方法を提供する。標的化生物コンジュゲートは、医学、薬学、及び生物医学研究分野における使用に適している。【選択図】なし