baber/WOPTO huggingface dataset:
Patent NZ-571508-A (NZ)
Title: Neutralizing human anti-IGFR antibody
IPC: C12P21/08
Filed: 2003-05-22
Abstract: Provided is a method for producing an anti-IGFR1 antibody using specified polynucleotides encoding the polypeptide in Chinese hamster ovary cells. Further provided are methods using suitable vectors comprising the polynucleotide and hygromycin B gene.
Patent NZ-576345-A (NZ)
Title: Hcv ns3 protease inhibitors
Inventor: LIVERTON NIGEL J
IPC: A61K38/06
Filed: 2007-10-23
Abstract: Disclosed are compounds comprising a cyclopropyl group and a pyrido group represented by general formula (I), or pharmaceutically acceptable salts or hydrates thereof. Also disclosed is the use of the compounds for treating an infection by hepatitis C (HCV) in subject.
Patent NZ-582566-A (NZ)
Title: Metal regulated polypeptides and methods of use from campylobacter spp.
Inventor: EMERY DARYLL A
IPC: C12N1/21
Filed: 2004-09-20
Abstract: Disclosed is a method for treating an infection in a non-human subject comprising: administering an effective amount of a composition to a subject having or at risk of having an infection caused by Campylobacter spp., the composition comprising isolated metal regulated polypeptides obtainable from a Campylobacter spp., wherein the composition comprises: at least six metal regulated polypeptides expressed by the Campylobacter spp., at a greater level when the Campylobacter spp. is grown in low metal conditions compared to growth of the Campylobacter spp. in high metal conditions, wherein the low metal conditions comprise an amount of metal no greater than the amount of metal present in a culture medium comprising at least 10 micrograms/ml of 2,2'-dipyridyl and wherein high metal conditions comprise at least one of the following: the absence of a chelator in a culture medium that comprises metal, and metal added to the culture medium. (62) Divided Out of 546601
Patent NZ-590053-A (NZ)
Title: Thiophene containing analogues of fluconazole as antifungal agents and process for their preparation
Inventor: BORATE HANUMANT BAPURAO
IPC: C07D409/12
Filed: 2009-10-01
Abstract: Disclosed herein is an antifugal compound of formula 1, where in R1 is CN or COOR' (wherein R'=methyl or ethyl), R2 and R3 is same or different and each represents a hydrogen, alkyl group of linear or branched chain of 1 to 20 carbon atoms or cycloalkyl group with 3 to 10 carb atoms; R4 and R5 is same or different and each represents a hydrogen or halogen selected from fluorine, chlorine or bromine. Also disclosed is a process for the preparation of compounds of formula 1 comprising: a. preparing alkyl 2-amino-4 and/or 5-substituted thiophene-3-carboxylate or 2-amino-4 and/or 5-substituted thiophene-3-carbonitrile of Formula 2, wherein R1 is CN or COOR' (wherein R'= methyl or ethyl), and R2 and R3 are as defined above, by Gewald synthesis; b. contacting alkyl 2-amino-4 and/or 5-substituted thiophene-3-carboxylate or 2-amino-4 andlor 5-substituted thiophene-3-carbonitrile of Formula 2 with formic acid and ammonium acetate at suitable temperature to obtain the corresponding alkyl 2-formylaminothiophene-3- carboxylates or substituted 2-formylaminothiophene-3-carbonitriles of the Formula 3, wherein RI, R2 and R3 are as defined above, and c. treating the compound of Formula 3 with epoxide of Formula 4, wherein R4 and R5 are as defined above, in presence of a base to obtain the compound of Formula 1.
Patent NZ-592488-A (NZ)
Title: Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Inventor: ANDERBERG JOSEPH
IPC: G16B40/10
Filed: 2009-11-10
Abstract: Disclosed are methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart- type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin- 12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries.
Patent NZ-594302-A (NZ)
Title: Beta-arrestin effectors and compositions and methods of use thereof
Inventor: YAMASHITA DENNIS
IPC: A61K38/08
Filed: 2009-12-28
Abstract: 594302 Disclosed is an isolated, recombinant or synthetic peptide comprising a sequence of Sar-Arg-Val-Ww-Zz-His-Pro-Cc, wherein: Ww is selected from the group consisting of: L-tyrosine, 3-hydroxy-L-tyrosine, 3-fluoro-L-tyrosine, 2,6-difluoro-L-tyrosine, 3-nitro-L-tyrosine, 3,5-dinitro-L-tyrosine, and 3-chloro-L-tyrosine; Zz is L-valine or L-isoleucine; and Cc is D-alanine; such as Sar Arg Val Tyr Ile His Pro Ala (XRVYIHPA).
Patent NZ-595259-A (NZ)
Title: Order taking method with wireless and internet-based communication and remote monitoring
Inventor: AWISZUS STEVEN T
IPC: G06Q10/00
Filed: 2007-02-01
Abstract: 595259 Disclosed is a method of taking an order for an establishment (12) which enables a customer to place an order for an item from the establishment (12). The establishment (12) has order placing equipment (14) located near the establishment (12) which is capable of receiving the order for the item from the customer. The method includes the steps of communicating the order from the order placing equipment (14) to a local order receiving facility (20a-20n) and monitoring the order by a remote facility (24). The monitoring by the remote facility (24) includes disabling communication from the remote order receiving facility (24) to the order placing equipment (14).
Patent NZ-596538-A (NZ)
Title: Haloalkyl heteroaryl benzamide compounds
Inventor: ROSSIGNOL JEAN-FRANCOIS
IPC: C07D277/46
Filed: 2010-05-11
Abstract: 596538 Disclosed herein are haloalkyl heteroaryl benzamide compounds of formula I, wherein the variables are defined in the specification, which show strong activity against hepatitis viruses. In one embodiment the compound is N-(4-trifluoromethyl-2-thiazolyl)-2-hydroxybenzamide.
Patent NZ-597336-A (NZ)
Title: Elisa for vegf
Inventor: MENG YU-JU G
IPC: G01N33/74
Filed: 2007-10-03
Abstract: 597336 Disclosed is a method for selectively detecting vascular endothelial growth factor (VEGF) forms greater than 110 amino acids (VEGF110+) in a biological sample, the forms including VEGF121, VEGF165, and longer isoforms, but not VEGF110, the method comprising the steps of: (a) contacting and incubating the biological sample with a capture reagent immobilized to a solid support, wherein the capture reagent comprises a 5C3 monoclonal antibody; (b) separating the biological sample from the immobilized capture reagents; (c) contacting the immobilized capture reagent-target molecule complex with a detectable antibody, wherein the detectable antibody is a A4.6.1 monoclonal antibody; and (d) measuring the level of VEGF110+ bound to the capture reagents using a detection means for the detectable antibody. Further disclosed is an immunoassay kit for selectively detecting VEGF110+ forms in a biological sample, the forms including VEGF121, VEGF165, and longer isoforms, but not VEGF110, the kit comprising: (a) as capture reagent, a 5C3 monoclonal antibody; and (b) as detection reagent, a A4.6.1 monoclonal antibody. Further disclosed is an antibody 5C3 obtained from or produced by hybridoma 5C3.1.1 deposit number PTA-7737 or a hybridoma thereof.
Patent NZ-630854-A (NZ)
Title: Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
Inventor: SMITH ERNEST S
IPC: C12Q1/70
Filed: 2013-04-26
Abstract: Discloses a fusion protein comprising (a) a first polypeptide segment comprising a heavy chain constant region domain and (b) a second polypeptide segment comprising the transmembrane domain of a vaccinia extracellular enveloped virus (EEV)-specific membrane protein.
Patent NZ-700217-A (NZ)
Title: Cushion for a respiratory mask assembly
Inventor: DAVIDSON AARON SAMUEL
IPC: A61M16/06
Filed: 2005-06-15
Abstract: A respiratory mask assembly for treatment of sleep disordered breathing is disclosed. The mask comprises a frame (see 12, figure 1) and a cushion (232; see also 14, figure 1) which at least in part defines a cavity. The cushion provides an aperture capable of receiving at least a patient’s nose. The cushion includes a face contacting portion (236), a non-face contacting portion (234), a gusset portion (238) connected between the face contacting portion and the non-face contacting portion, and an air delivery connection supported by the frame and adapted to connect an air delivery conduit to supply air to the cavity. The gusset portion includes an underside notch (249) and is configured so that the cushion is less stiff at a nasal bridge region. When the mask is compressed against a user’s face, the notch will cause the walls of the cushion to collapse at the weakest point, allowing further travel of the mask toward and away from the user’s face.
Patent NZ-702387-A (NZ)
Title: Compositions and methods for increasing the stability of food product additives
Inventor: GAREAU AMBER LYNN
IPC: A23L29/00
Filed: 2012-05-21
Abstract: Disclosed are compositions including powdered green tea extract and a powdered preparation comprising polyunsaturated fatty acids. Also disclosed are methods of preparing the compositions and using the compositions in food products, as well as food products containing or that are prepared from the compositions.
Patent NZ-703260-A (NZ)
Title: Polysaccharide compositions and methods of use
Inventor: PIER GERALD B
IPC: G01N33/569
Filed: 2013-05-30
Abstract: The invention relates to the use of compositions of poly N-acetylated glucosamine (PNAG) and antibodies specific to PNAG in the prevention and treatment of infections by non-ica/pga PNAG-positive pathogens and in detection (including diagnostic) methods. Also provided are methods of producing PNAG polysaccharides utilising non-ica/pga PNAG-positive microbes.
Patent NZ-703281-A (NZ)
Title: Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
Inventor: GALETTO ROMAN
IPC: A61K35/17
Filed: 2013-05-13
Abstract: Methods for developing engineered T-cells for immunotherapy that are both non-alloreactive and resistant to immunosuppressive drugs. The present invention relates to methods for modifying T-cells by inactivating both genes encoding target for an immunosuppressive agent and T-cell receptor, in particular genes encoding CD52 and TCR. This method involves the use of specific rare cutting endonucleases, in particular TALE-nucleases (TAL effector endonuclease) and polynucleotides encoding such polypeptides, to precisely target a selection of key genes in T-cells, which are available from donors or from culture of primary cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections.
Patent NZ-714062-A (NZ)
Title: An encasement
Inventor: ANDREW LEO HAYNES
IPC: E03B7/09
Filed: 2014-11-14
Abstract: This invention relates to an encasement (or utility housing) for a plumbing configuration. The encasement comprises a formed enclosure, the enclosure being mountable to a wall or a part of a wall or a support structure. The formed enclosure is a first housing portion, with the first housing portion providing for a cavity space. A second housing portion is receivable by, or co-locatable with, the first housing portion, and the second housing portion is receivable or co-locatable within the cavity space of the first housing portion. At least a part of the second housing portion comprises a plumbing configuration configured to receive, or be in fluid communication with, a flow of fluid and to channel the received flow of fluid to an outlet from the plumbing configuration. There is a desire to provide for plumbing configurations which are not exposed, or which provide other plumbing configuration benefits not previously contemplated by traditional plumbing work. The position of the second housing portion is longitudinally adjustable with respect to the first housing portion by re-positioning the engagement of the second housing portion co-locating devices with respect to the first housing portion co-locating devices. In such a re-positioning, the inlet of the plumbing configuration is moved or relocated (for example up or down within the cavity space). The first housing portion defines the cavity space by at least a rear wall, and each of a pair of substantially opposing side walls and a pair of substantially opposing top and bottom walls. The inner surfaces of each of the substantially opposing side walls of the first housing portion comprise the one or a series of co-locating devices. Re-positioning of the second housing portion is provided so that the inlet to the plumbing configuration or arrangement can be best positioned for making a fluid connection to the outlet of a device or appliance of other fluid (e.g. liquid) discharging device.
Patent NZ-715389-A (NZ)
Title: Mechanisms for deriving an accurate timing signal from a noisy waveform
Inventor: HALL RICHARD
IPC: G01P3/489
Filed: 2014-05-22
Abstract: Deriving a clean timing signal from a waveform is disclosed. A sensor-of-interest (SOI) sample set and a waveform sample set that correspond to the SOI sample set in time is collected. The waveform sample set contains information which allows to determine the angular speed of a rotating machinery. The waveform sample set is partitioned into a plurality of waveform sample subsets, and the SOI sample set is partitioned into a plurality of SOI sample subsets, each SOI sample subset corresponding to one of the plurality of waveform sample subsets. A plurality of waveform sample subset angular speeds is determined, wherein each waveform sample subset angular speed corresponds to a different waveform sample subset. An aggregate mean angular speed based on the plurality of waveform sample subset angular speeds is determined. Each SOI sample subset is resampled to the aggregate mean angular speed based on the corresponding waveform sample subset angular speed to generate a plurality of resampled SOI subsets. In this way, the effect of speed variations on the sampling of the sensor signals can be compensated and sensed parameters may be aligned with the angular position of the rotating member. Special measures based on expected pulse lengths can be taken to ensure that correct angular speed and angular position determinations can be made based on noisy voltage or current signals of electrical machines.
Patent NZ-716204-A (NZ)
Title: Code support and capsule for preparing a beverage by centrifugation, system and method for preparing a beverage by centrifugation
Inventor: KAESER STEFAN
IPC: G06K19/06
Filed: 2014-09-29
Abstract: The invention relates to a code support to be associated with or part of a capsule intended for delivering a beverage in a beverage producing device by centrifugation of the capsule. The support comprises a code formed by at least a first sequence of symbols. The code is represented on the support so that each symbol is sequentially readable by a reading arrangement of an external reading device while the capsule is driven in rotation along an axis of rotation. The first sequence comprises at least one first data sequence formed by at least two sub-sequences of symbols. Each one of said at least two sub-sequences further comprises at least one error-checking symbol for allowing a validity check of the symbols of said subsequence.
Patent NZ-721908-A (NZ)
Title: Combination therapy with neoantigen vaccine
Inventor: HACOHEN NIR
IPC: C07K16/28
Filed: 2014-12-19
Abstract: The present invention relates to neoplasia vaccine or immunogenic composition administered in combination with other agents, such as checkpoint blockade inhibitors for the treatment or prevention of neoplasia in a subject.
Patent NZ-725119-A (NZ)
Title: A dentifrice composition
Inventor: HILKE BJORN
IPC: A61K8/21
Filed: 2015-03-25
Abstract: A dentifrice composition comprises a toothpaste carrier having a pH of about 7 to about 10 and a calcium ion source and a fluoride ion source wherein the calcium ion source is unencapsulated and the fluoride ion source is encapsulated or coated in a coating impermeable to the toothpaste carrier. The coating degrades to release fluoride ions when mechanically agitated by a toothbrush in an oral cavity surface. In a second embodiment, the dentifrice composition comprises an aqueous toothpaste carrier having a pH of about 7 to about 10 with an unencapsulated calcium ion source and a fluoride ion source having a pH of between 3 to less than 7 wherein the fluoride ion source is encapsulated in a first (or inner) impermeable coating adapted to degrade to release the fluoride ions in the presence of a toothpaste carrier. The first coating is encased in a second (or outer) impermeable coating adapted to resist degradation in the presence of the toothpaste carrier and to mechanically degrade to expose the first (or inner coating) which degrades to release the fluoride ions in response to application of the dentifrice composition to an oral cavity surface.
Patent NZ-729645-A (NZ)
Title: Apparatus and method for feeding an animal
Inventor: OLIVER TIMOTHY MICHAEL
IPC: A01K5/01
Filed: 2015-08-04
Abstract: A slow feeder includes a container for, in use, containing food for an animal. The container has a side wall through which a slot (26) is defined; and a feeding restrictor (6). The feeding restrictor (6) comprises a food-covering element through which at least one opening is defined for, in use, resting on top of the food such that the animal can access the food through the opening; a locating element which extends from the food-covering element through the slot; and a retaining element (34) extending from the locating element and movably engageable with an outer portion of the container. The engagement of the retaining element (34) with the outer portion of the container retains the restrictor (6) in the container. This addresses a prior art problem of a feeding restrictor tilting and jamming as it moves down in use.
Patent NZ-732546-A (NZ)
Title: Absorbent article
Inventor: SUGIYAMA KATSUHIKO
IPC: A61F13/53
Filed: 2015-12-09
Abstract: The present invention relates to an absorbent article for effectively utilising the entire absorber by quickly diffusing a body fluid, suppresses unpleasant dampness and twisting after absorption of the body fluid, and thus reduces discomfort in a wearer. The absorbent article (10) of the present invention includes a liquid permeable top surface sheet (14), a liquid impermeable back surface sheet (12), and an absorber (13) disposed between the top surface sheet (14) and the back surface sheet (12). A top surface sheet (14) side of the absorbent article is provided with extending a plurality of compressed lines (23) in each of which a plurality of recess portions (22) formed by compressing the top surface sheet (14) and the absorber (13) are arranged. The plurality of compressed lines (23) form intersection regions (21D) where the compressed lines intersect with each other. The compressed recess portions (22) are not formed in the intersection regions (21D).
Patent NZ-740351-A (NZ)
Title: Immunity enhancing agent for cancer by allergin-1 antagonist
Inventor: SHIBAYAMA SHIRO
IPC: A61K45/06
Filed: 2016-09-02
Abstract: The present invention addresses the problem of providing a medicinal agent for suppressing the progression and recurrence of cancer and/or for treating cancer, the medicinal agent comprising a novel active ingredient having the effect of enhancing immunity to cancer. This Allergin-1 antagonist has the effect of enhancing immunity to cancer, and can be used for suppressing the progression and recurrence of cancer and/or for treating cancer. In particular, this Allergin-1 antagonist is useful for treating cancer patients for whom the therapeutic effects of anti-tumor immunotherapeutic agent are insufficient, or useful for cancer treatments in combination with anti-cancer drugs.
Patent NZ-741282-A (NZ)
Title: A building
Inventor: BREE CHARLES CAULDER
IPC: E04B1/35
Filed: 2018-04-03
Abstract: This invention relates to a building. There is a problem in many parts of the world when it comes to meeting demand for buildings that can be produced quickly and economically, and then conveniently transported to the site of need. Such buildings may for example be required for short or long-term accommodation, event offices, storage of items, recreational purposes or other uses. It is an object of preferred embodiments of the invention to go at least some way towards addressing this. In one aspect the invention there is a method of forming a building, comprising obtaining a mould, spraying a first spray material onto the outside of the mold so that it sets generally in the shape of the mould to provide a core. The core has side walls, an end wall integral with the side walls, and a roof integral with both the side walls and end wall. A second spray material different to the first spray material is sprayed onto the inner and outer surfaces of the core to give it a rigid skin.
Patent NZ-759443-A (NZ)
Title: Agricultural compositions
Inventor: VADAKEKUTTU Thankapan
IPC: C05G5/12
Filed: 2018-05-10
Abstract: The invention relates to an agricultural water disintegrable granular composition. More particularly, the invention relates to a water disintegrable granular composition, where the granules include at least one water insoluble crop nutrient or algae or pesticidal active ingredient, and one or more agrochemically acceptable excipient, whereby the granules have a bulk density of less than 1.5 gm/ml and hardness of at least 1 Newton. The present invention also provides a process of preparing the water disintegrable granular composition and a method of fortification of the plants or the soil or the plant propagation material or locus thereof with the water disintegrable granular composition.
Patent NZ-764838-A (NZ)
Title: Antimicrobial peptides and methods of using same
Inventor: SHEEHAN DEREK JAMES
IPC: C07K14/78
Filed: 2018-12-05
Abstract: Antimicrobial peptides of 18-21 amino acids in length with the formula SEQ ID NO: 1, being KWCFRVCYRGICYRRCRD, with up to four optional substitutions at K1R, K1G, W2F, W2R, F4V, F4W, R5Y, Y8R, R9G, G10R, I11A, I11F, I11V, R14H, R15K, or R17N, and further optionally P at the N-terminus to enable D-P bonded multimers. Also provided are formulations comprising said peptides and methods of using said peptides for treating bacterial infections in a mammal.
Patent PT-104037-A (PT)
Title: Sistema misturador com função de poupança de água e respectivo processo de utilização
Inventor: COSTA VITOR ANTONIO FERREIRA D
IPC: B01F7/08
Filed: 2008-04-26
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM SISTEMA MISTURADOR DE ÁGUA CONSTITUÍDO POR UMA VÁLVULA MISTURADORA ASSOCIADA A UM SISTEMA DE ACUMULAÇÃO QUE PERMITE POUPAR ÁGUA EM INSTALAÇÕES DOMÉSTICAS. SE A ÁGUA NA ENTRADA (11) NÃO ESTÁ QUENTE É ENCAMINHADA PARA O RESERVATÓRIO (18). SE A ÁGUA NA ENTRADA (11) ESTÁ QUENTE OU O ACUMULADOR (18) ESTÁ CARREGADO A ÁGUA QUE FLUI PELA ENTRADA (11) É ENCAMINHADA PARA A ZONA DE DESCARGA DA VÁLVULA (13). ENQUANTO HOUVER ÁGUA RETIDA NO RESERVATÓRIO (18) ESTA SERÁ ENCAMINHADA PARA A ENTRADA DE ÁGUA FRIA (12) PREFERENCIALMENTE À ÁGUA FRIA DA REDE (17), PROMOVENDO ASSIM A POUPANÇA DE ÁGUA POTÁVEL. A PRESENTE INVENÇÃO É APLICÁVEL NA INDÚSTRIA DA CONSTRUÇÃO CIVIL, E MAIS CONCRETAMENTE EM INSTALAÇÕES DE ÁGUA PARA USO DOMÉSTICO.