baber/WOPTO huggingface dataset:
Patent EA-003370-B1 (EA)
Title: Novel 2,3,3a,4,9,9a hexahydro-8-hydroxy-1h-benz[f]indoles, a methods for the production thereof, and their use as medicaments
Inventor: GRAUERT MATTHIAS
IPC: A61P25/28
Filed: 1999-07-22
Abstract: 1. An indole compound of formula 1 wherein X is a single bond, -O-, C1-C4alkyl, C1-C3 alkoxy, -O-CH2-CH2-O- or -O-CH2-CH2-NH-; R<1> is hydrogen, methyl, ethyl or phenyl; R<2> is hydrogen or methyl; R<3> is hydrogen, F, Cl, Br, hydroxy or methoxy; R<4> is hydrogen, methyl or ethyl; R<5> is hydrogen, methyl or ethyl; R<6> is hydrogen, methyl or ethyl; R<7> is tert-butyl, cyclohexyl, n is an integer 0 or 1; Y is N or CH; Z is O, NH or S; R<8> is hydrogen, methyl, F, Cl, Br or methoxy; R<9> is hydrogen, methyl, F, Cl, Br or methoxy. 2. Compounds according to claim 1, characterised in that they are present in traps form. 3. Pharmaceutical preparation, characterised in that it contains a compound according to claim 1 and the acid addition salts thereof together with conventional adjuvants and carriers. 4. Use of a compound according to claim 1 as a pharmaceutical composition. 5. Use of a compound according to claim 1 for preparing a medicament for antagonising the release of glutamate. 6. Use according to claim 5, for preparing a medicament for treating arrhythmias, spasms, cardiac and cerebral ischaemias and neurodegenerative diseases. 7. Use according to claim 5, for the preparation of a medicament for treating epilepsy, hypoglycaemia, hypoxia, anoxia, cerebral trauma, cerebral oedema, stroke, perinatal asphyxia, amylotropic lateral sclerosis, Huntington's disease, Alzheimer's disease, Parkinson's disease, cyclophrenia, hypotonia, cardiac infarct, heart rhythm disorders, angina pectoris, pain of various origins, particularly for treating neuropathies. 8. Use according to claim 4, for the preparation of a local anaesthetic. 9. Process for preparing compounds of general formula 1, characterised in that the nitrogen by reacting the educt of general formula 2 or 3 this is reacted by methods known per se from the prior art with an acylating agent, wherein Y denotes a leaving group which may be substituted for nitrogen, to form the corresponding intermediate product of general formula 11 and this is then also reduced, by methods known per se from the prior art, to form the corresponding indole derivative of general formula 1 and the reaction product of general formula 1 is isolated. 10. Process for preparing compounds of general formula 1, characterised in that the nitrogen is reacted by reacting the educt of general formula 2 or 3 with an aldehyde to form the intermediate product of general formula 12 and this is reduced by methods known per se from the prior art to form the end product of general formula 1 and this is isolated.
Patent EA-006284-B1 (EA)
Title: High frequency network multiplexed communications over various lines using multiple modulated carrier frequencies
Inventor: ABRAHAM CHARLES
IPC: H04L25/02
Filed: 2003-01-31
Abstract: An apparatus is provided for high frequency multiplexed electrical line communication for cable TV, telephone, internet, security and other control applications over the mid and low voltage power lines and directly through the transformers. The apparatus includes a transmitter, a receiver, a modem (14), a multiplexer and multiple couplers (28) at each of two or more locations along an electrical line (18). The couplers have capacitive circuits serially connected with an air-core or dielectric-core transformer. The capacitive circuits resonate with the transformer (22) at a preselected frequency. The coupler (28) eliminates noise and is matched to the characteristic impedance of the line at the preselected frequency, which linearizes communication on the line and allows high speed data and voice communication over long distances. Multiple modulators and demodulators are used to produce multiple modulated carrier frequencies.
Patent EA-008082-B1 (EA)
Title: System for realising complex assemblies
Inventor: TUSACCIU EDOARDO
IPC: G09B23/00
Filed: 2005-07-18
Abstract: The invention concerns a system for realising complex constructions, characterised in that it comprises a plurality of basic elements, and a plurality of constructive and/or figurative elements, that can be coupled with said basic elements, each basic element being comprised of ferromagnetic material, to be coupled with a first type of constructive and/or figurative magnetic elements, said basic elements being further provided with not-magnetic coupling means, for coupling with at least a second type of plastic material elements, said plastic material elements being provided with coupling means corresponding to the coupling means provided on said plurality of basic elements.
Patent EA-009119-B1 (EA)
Title: 4-((phenoxyalkyl)thio)phenoxyacetic acids and analogs
Inventor: KUO GEE-HONG
IPC: C07C323/20
Filed: 2004-09-16
Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
Patent EA-015454-B1 (EA)
Title: Sole for shoes of the waterproof and vapo-permeable type, and shoe provided with said sole
Inventor: POLEGATO MORETTI MARIO
IPC: A43B7/12
Filed: 2007-05-31
Abstract: A sole (10, 100, 200, 300) for shoes, of the waterproof and vapor-permeable type, comprising a lower element (11, 111, 211, 311) made of plastic material, on which a tread (12) provided with multiple through holes (13) is formed; a membrane (14, 214, 314) which is impermeable to water and permeable to water vapor and is arranged above said lower element (11, 111, 211, 311) so as to be superimposed on the through holes (13), the membrane being joined perimetrically and hermetically to at least one component of the sole (10, 100, 200, 300) so as to avoid the rise of liquids through the sole; vapor-permeable or perforated means (17) for protecting the membrane (14, 214, 314), which are arranged below the membrane (14, 214, 314) so as to be superimposed on the area of the holes (13). The sole has means (17) for protecting the membrane (14, 214, 314) comprising individual vapor-permeable or perforated protective elements (18, 118, 218, 318), each arranged so as to block a corresponding through hole (13). The lower element (11, 111, 211, 311) forms, for each through hole (13), an undercut region (19, 119, 219a, 219c, 219d, 219e) for preventing downward extraction for each protective element (18, 118, 218, 318). The membrane (14, 214, 314) covers the through holes (13) and is joined perimetrically and hermetically to the lower element (11, 111, 211, 311) so as to form perimetrically one sealing (16).
Patent EA-013398-B1 (EA)
Title: Decomposition of waste products formed in slurry catalyst synthesis
Inventor: REYNOLDS BRUCE E
IPC: C01C1/24
Filed: 2007-12-05
Abstract: This application discloses a process for decomposition of ammonium sulfate found in a stream comprising ammonium sulfate and slurry catalyst in oil. The ammonium sulfate is broken down into ammonia and hydrogen sulfide gas. These gases have many uses throughout the refinery, including the preparation of slurry hydroprocessing catalyst.
Patent EA-017228-B1 (EA)
Title: A stove
Inventor: WALSH DERMOT
IPC: F24C3/14
Filed: 2008-03-31
Abstract: The stove (1) has a fuel reservoir formed by a cylindrical canister (2). A stop valve (3) is mounted at a top of the canister (2) for regulating supply of fuel gas from the canister (2) through a fuel passage to a burner head (4) mounted on top of the stop valve (3). The fuel passage has an inlet (5) in the canister (2) and an outlet at the burner head (4) and extends through the stop valve (3) which is mounted in the fuel passage. The stop valve (3) is a rotary valve controlled by a hand wheel (6) which can be rotated by a user to move the stop valve (3) between open and closed positions. An emergency shut-off valve (7) is mounted at the inlet (5) to the fuel passage and is operable when the stove (1) is knocked over.
Patent EA-019370-B1 (EA)
Title: Fviii peptides and their use in tolerising haemophiliacs
Inventor: WRAITH DAVID
IPC: A61K38/37
Filed: 2008-12-03
Abstract: The present invention provides a peptide comprising a core residue sequence derivable from human FVIII which peptide is capable of binding to an MHC class II molecule without further antigen processing. The present invention also relates to the use of such peptides for the prevention or suppression of inhibitor antibody formation in haemophilia A and/or acquired haemophilia.
Patent EA-019204-B1 (EA)
Title: Adenine derivatives and use thereof in therapy
Inventor: BAZIN-LEE HELENE
IPC: A61K31/522
Filed: 2009-08-07
Abstract: Compounds of formula (I)wherein Ris Calkylamino, or Calkoxy; Ris a group having the structuren is an integer having a value of 1 to 6; Het is a 6-membered saturated heterocycle containing one nitrogen atom wherein Het is attached to the -(CH)- moiety at any carbon atom of the heterocycle; Ris hydrogen, Calkyl, or CcycloalkylCalkyl; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Patent EA-021278-B1 (EA)
Title: Solar panel tube
Inventor: SPINELLI PAOLO
IPC: F24J2/46
Filed: 2010-12-20
Abstract: Solar panel tube, comprising a first pipe (11); a second pipe (12); a first insulating material (13) surrounding said first pipe; a second insulating material (14) surrounding said second pipe; said first insulating material comprising a supporting layer treated with aerogel; said second insulating material comprising a supporting layer treated with aerogel; wherein said first and second insulating materials (13, 14) are wrapped in a nylon thread winding (20) and said first and second insulating material are further wrapped by a protective layer (15).
Patent EA-030335-B1 (EA)
Title: Use of amisulpride as an anti-emetic
Inventor: GILBERT JULIAN CLIVE
IPC: A61P1/08
Filed: 2011-03-10
Abstract: Provided is the use of amisulpride as a medicament in the therapy of a condition selected from post-operative, chemotherapy-induced or opioid-induced nausea and vomiting.
Patent EA-030276-B1 (EA)
Title: Methods of identifying patients suffering from cancer and treating cancer in patients having or developing resistance to a first cancer therapy
Inventor: GARRAWAY LEVI A
IPC: C12Q1/68
Filed: 2011-03-09
Abstract: The present invention relates to medicine. Specifically, the invention relates to a method of identifying a subject having cancer who is likely to benefit from treatment with a combination therapy with a RAF inhibitor and a MEK, CRAF, CrkL or TPL2/COT inhibitor by assaying an increased gene copy number, a mRNA or a protein level or a phosphorylation level of one or more kinase targets MAP3K8 (TPL2/COT), CRKL (CrkL), FGR (Fgr), PRKCE (Prkce), PRKCH (Prkch), ERBB2 (ErbB2), AXL (Axl) or PAK3 (Pak3) in comparison with analogous characteristics in a a subject without the cancer. A method of treating cancer is also provided comprising administering to a subject an effective amount of a RAF inhibitor and an effective amount of a MEK inhibitor or a TPL2/COT inhibitor.
Patent EA-022522-B1 (EA)
Title: System for electrochemical generation of hypochlorite
Inventor: BENEDETTO MARIACHIARA
IPC: C25B11/04
Filed: 2011-06-17
Abstract: The invention relates to a system for a point-of-use electrochemical generation of hypochlorite on demand in a wide range of volumes and concentration. The system is provided with a processor which adjusts the electrolyte composition, the current density and the electrolysis time, commanding an alert system capable of warning in advance whenever the replacement of electrodes is needed. Automated detection of the insertion and the correct type of several collecting vessels can also be provided, triggering the set-up of electrolysis parameters accordingly.
Patent EA-028573-B1 (EA)
Title: Method for producing high vcm coke
Inventor: FAEGH AHMAD
IPC: C10L5/04
Filed: 2012-05-10
Abstract: A process and apparatus for improving the production of coke having a high volatile combustible material content are disclosed. The process may include, for example: heating a coker feedstock to a coking temperature to produce a heated coker feedstock; contacting the heated coker feedstock with a quench medium to reduce a temperature of the heated coker feedstock and produce a quenched feedstock; feeding the quenched feedstock to a coking drum; subjecting the quenched feedstock to thermal cracking in the coking drum to (a) crack a portion of the quenched feedstock to produce a cracked vapor product, and (b) produce a coke product having a volatile combustible material (VCM) concentration in the range from about 13 to about 50% by weight, as measured by ASTM D3175.
Patent EA-037617-B1 (EA)
Title: Method and system for detecting an intrusion in data traffic on a data communication network
Inventor: ZAMBON EMMANUELE
IPC: H04L29/06
Filed: 2012-07-26
Abstract: An method and an electronic digital computer for detecting an intrusion in data traffic on a data communication network, the method comprising the steps of parsing the data traffic to extract at least one protocol field of a protocol message of the data traffic; associating the extracted protocol field with a model for that protocol field, the model being selected from a set of models; assessing if a contents of the extracted protocol field is in a safe region as defined by the model; and generating an intrusion detection signal in case it is established that the contents of the extracted protocol field is outside the safe region. The set of models may comprise a corresponding model for each protocol field of a set of protocol fields.
Patent EA-030950-B1 (EA)
Title: Kit comprising a hair conditioning composition and an activator composition
Inventor: BRIGGS STEPHEN LEONARD
IPC: A61Q5/12
Filed: 2013-05-24
Abstract: Provided is a kit comprising an aqueous hair conditioning composition comprising a cationic surfactant and fatty alcohol, and an anhydrous activator composition comprising polyalkylene glycol. Also provided is a method of treating the hair comprising applying an activator composition to a hair conditioning composition, mixing, and then applying to the hair. Further provided is a method of treating the hair comprising applying a hair conditioning composition to the hair and then applying an activator composition to the hair. Also provided is a method of texturising a hair conditioning composition by mixing with an activator composition.
Patent EA-028694-B1 (EA)
Title: Apparatus for carrying a grenade
Inventor: MOLCHO HAIM
IPC: F42B39/02
Filed: 2013-10-01
Abstract: The subject matter discloses an apparatus (600), having an envelope (610) and a base (608) for holding a grenade (602), a rear cover (665) connected to the envelope (610) for attaching said envelope (610) to a vest; a top cover (630) to secure the grenade (602) from above when positioned in a downward position and moving upwards to an upward position; a spring (640) connected to the top cover (630) and to the envelope (610) and a button (621, 622) that causes the top cover (630) to move to the upward position when pressed by the user. The button (621, 622) is located below the top cover (630) and connected only to one of the envelope (610) or the rear cover (665). The user of the apparatus (600) can release the grenade (602) from the apparatus while pressing the button (621, 622) and the envelope (610) is designed to enable the user to hold the grenade (602) and the grenade lever (605) singlehandedly when pressing the button (621, 622) and when releasing the grenade (602) from the apparatus (600).
Patent EA-031324-B1 (EA)
Title: Correctly folded etanercept in high purity and excellent yield
Inventor: ARAKAWA TSUTOMU
IPC: A61K38/16
Filed: 2013-09-10
Abstract: A mixed mode chromatography method for separating correctly folded from incorrectly folded conformations of a given protein is provided. The method is highly effective in separating correctly folded etanercept from incorrectly folded etanercept and aggregates in commercially attractive yields capable of affording etanercept preparations having very high purity in terms of correctly folded etanercept versus incorrectly folded etanercept. The invention is further directed to protein preparations and formulations comprising correctly folded proteins obtained using the present methods, and methods of treatment using the high purity preparations obtained from the mixed mode method.
Patent EA-028737-B1 (EA)
Title: Butt joint of insulated pipes or shaped products
Inventor: PAVLYUK EVGENY SERGEEVICH
IPC: F16L59/00
Filed: 2016-10-10
Abstract: A butt joint of pre-insulated pipes or shaped products comprises interconnected internal working pipes and a sleeve, fixed with overlap on the outer pipe-shells, made of translucent plastic. The novelty consists in that the sleeve is heat-shrinkable, made of translucent plastic, and between the sleeve and the outer pipe-shells there is placed an adhesive material which is different in color from the color of the pipe-shell. The technical result achieved by the invention consists in preserving the properties and characteristics of insulation in the areas of butt joints for a long period of time and increasing the service life of the joint and, correspondingly, piping systems due to formation of a reliable tight joint "heat-shrinkable sleeve - pipe-shell".
Patent EA-030936-B1 (EA)
Title: Non-burning-type flavor inhaler
Inventor: TAKEUCHI MANABU
IPC: A24F40/53
Filed: 2015-04-30
Abstract: The application describes a non-burning type flavor inhaler comprising a housing having an air flow path that continues from an inlet to an outlet; an atomizer configured to atomize an aerosol source without burning; a sensor configured to output a value that changes in accordance with a puff action of a user; and a controller configured to detect a puff action of the user when a response value derived from a value that is output from the sensor satisfies an inhaling condition, the controller configured to identify that the user is an authorized user when the response value satisfies an identification condition that is different from the inhaling condition.
Patent EA-035615-B1 (EA)
Title: Device for massaging and tumbling of meat for processing
Inventor: CHOMANOV URISHBAJ CHOMANOVICH
IPC: A22C9/00
Filed: 2016-12-28
Abstract: The invention relates to meat processing industry, in particular, to devices for massaging and tumbling of meat, and can be applied in production of salted meat products at meat processing plants. A device comprises a rotary driven drum (1) with four curved perforated blades (3) arranged along the diameter on the inner cylinder surface of the rotary drum (1), a hatch for loading and unloading the product and an intake nipple for the vacuum system. U-shape blades (4) are arranged accordingly opposite to each of said perforated blades (3) on the surface of a rotary shaft (7), each of U-shaped blade having flutes (5) on its surface. Said blades (3) and U-shaped blades (4) are arranged is such a way that, during rotation of the device, the processed product (2) drops from blades (3) to a respective U-shaped blade (4). The drum (1) is preferably made of stainless steel. The technical result of the invention is improvement of meat salting process quality by ensuring effective use of the massaging process with simultaneous tumbling at all phases of mechanical processing of meat.
Patent EA-032216-B1 (EA)
Title: Multimodal polyethylene
Inventor: GARG PRIYA
IPC: C08L23/06
Filed: 2015-06-23
Abstract: The invention is directed to polyethylene having a multimodal molar mass distribution, having a density in the range from 940 to 948 kg/m, having an MFIin the range from 1.0 to 3.5 g/10 min and comprising from 45 to 47 wt.% of an ethylene copolymer A and from 53 to 55 wt.% of an ethylene copolymer B, where all percentages are based on the total weight of the composition wherein ethylene-1-butene copolymer A has a viscosity number in the range between 70 and 110 cm/g and a density between 960 and 973 kg/m. The polyethylene is suitable to be applied in pipe coating applications.
Patent EA-035368-B1 (EA)
Title: Glycopeptide compositions
Inventor: JASPRICA IVONA
IPC: A61K47/26
Filed: 2015-11-06
Abstract: Solutions comprising a glycopeptide antibiotic, for example vancomycin, and an amino acid or amino acid derivative such as N-acetyl-glycine or N-acetyl-D-alanine are provided. These solutions are stable or stabilized for long-term periods at conditions of normal use and storage, and can be formulated as pharmaceutical solutions for use in subjects. Methods of manufacturing and using these solutions are also provided, as are methods of stabilizing a glycopeptide antibiotic, for example vancomycin, using amino acids or amino acid derivatives such as N-acetyl-glycine or N-acetyl-D-alanine.
Patent EA-037468-B1 (EA)
Title: Method, solution and product for cleaning, sanitizing and hygienization of contaminated surface and use of said solution and product
Inventor: RODOLFI ALBERTO
IPC: C11D3/38
Filed: 2016-04-20
Abstract: A method, a solution and a product for cleaning, sanification and hygienization of a contaminated surface and the use of said solution and product, wherein the solution comprises probiotic bacteria spores and bacteriophages having antimicrobial effect, and the product comprises a solution with detergent, sanificant and hygienizing action, to which probiotic bacteria and bacteriophage elements are mixed; the probiotic bacteria being preferably of the Bacillus subtilis, Bacillus megaterium and Bacillus pumilus genera, while the bacteriophage elements comprise, as an alternative or in combination, bacteriophages of the Caudavirales, Microviridae, Leviviridae, Inoviridae, Tectiviridae, Corticoviridae families.
Patent EA-034807-B1 (EA)
Title: Reservoir assembly for a personal vaporizer device
Inventor: ROGAN ANDREW ROBERT JOHN
IPC: A24F40/485
Filed: 2016-12-02
Abstract: The present invention provides a reservoir assembly (1) for a personal vaporizer device (100), such as an electronic smoking article or an e-cigarette. The reservoir assembly (1) comprises a housing (2) which encloses a reservoir (3) for storing a liquid to be vaporized, wherein the housing (2) and/or the reservoir (3) define a flow path (P) for the liquid from the reservoir (3) for vaporization of the liquid. The reservoir assembly (1) further comprises a mouthpiece (5) provided in or on the housing (2) and defining a channel (C) for conveying vapour formed from the liquid to a user's mouth. The mouthpiece (5) is configured for movement between a first position (A) and a second position (B), wherein the flow path (P) is closed or blocked when the mouthpiece (5) is in the first position (A) and wherein the flow path (P) is open in the second position (B). The invention also provides a personal vaporizer device (100), such as an etectronic smoking article or an e-cigarette, which includes such a reservoir assembly (1).