baber/WOPTO huggingface dataset:
Patent EP-0700285-B1 (EP)
Title: A drug delivery composition for alpha-adreno receptor blocking agents
Inventor: ILLUM LISBETH
IPC: A61K9/00
Filed: 1994-05-27
Granted: 1998-09-23
Abstract: The invention provides an oral drug delivery composition comprising an  alpha  -adreno receptor blocking drug characterised in that the composition is adapted to release a first portion of the drug in the upper gastrointestinal tract and to release a second portion of the drug by sustained release in the terminal ileum and/or the colon. This composition provides a two phase release profile which maintains sufficient and steady plasma levels for therapeutic effect whilst minimising side effects by avoiding a high peak in plasma levels. The sustained release of the second and optionally the first portion of the drug is achieved by a controlled release system such as a hydrophilic gel matrix. The specific release of the second portion of the drug in the colon can be achieved by coating tablets containing the second portion with a pH or redox sensitive coating such as a polymethylmethacrylate.
Patent EP-0716743-B1 (EP)
Inventor: DYLLICK-BRENZINGER RAINER
IPC: G01N33/28
Filed: 1994-08-25
Granted: 2000-06-14
Abstract: PCT No. PCT/EP94/02824 Sec. 371 Date Mar. 4, 1996 Sec. 102(e) Date Mar. 4, 1996 PCT Filed Aug. 25, 1994 PCT Pub. No. WO95/07460 PCT Pub. Date Mar. 16, 1995A method for detecting naphthylamines which are present as tracers in mineral oils, wherein the naphthylamine is extracted by treating the mineral oil with an aqueous medium, and is coupled in the aqueous phase with a diazonium salt to form an azo dye, the use of specific naphthylamines as tracers in mineral oils and mineral oils containing these specific naphthylamines.
Patent EP-0715565-B1 (EP)
Inventor: MAZEIKA LINAS
IPC: B29L21/00
Filed: 1994-08-30
Granted: 2000-03-01
Abstract: The invention provides for a method of molding an elastomeric material which avoids longitudinal mold lines and an improved molding composition as well as molded parts for hybrid insulators and the like.
Patent EP-0667406-B1 (EP)
Inventor: MAKIPIRTTI SIMO
IPC: D04H1/42
Filed: 1995-02-13
Granted: 1999-04-21
Abstract: The process according to the invention aims at partly solving the difficult radiation sterilization problem of polypropylene non-woven fabrics resulting from the low resistance to gamma-radiation of the draw-oriented fibre polymer. According to the invention, the gamma-radiation induced damages to the physical properties of polypropylene can, in addition to the choice of polymer and use of stabilizing additives, be reduced by regulating, in the fibre production, the super- and microstructures of the polymer matrix and by preventing detrimental structural changes of the polymer during the production and post-treatment processes of the fibre and non-woven fabric. When carrying out the process, the melt spinning and drawing processes in the fibre production are regulated so that the product fibre to its superstructure is in the area of deformed spherulites, to its microstructure in the monoclinic-amorphous structural system, to its crystallinity higher than about 15 mass-% and to its average chain orientation above the value of about 0.6 (60%). According to the process, care should be taken so as not to exceed an actual polymer matrix temperature of about 120  DEG C in the fibre and non-woven fabric production processing stages following the melt spinning, especially at average chain orientation values of the fibre structure of between 0.60 (60%) and 0.76 (76%).
Patent EP-0690504-B1 (EP)
Inventor: ATKINSON NYE HENRI III
IPC: H05K3/34
Filed: 1995-05-19
Granted: 2001-11-21
Abstract: An process and a structure for an improved solder terminal is disclosed. The improved solder terminal is made of a bottom metallic adhesion layer, a CrCu intermediate layer on top of the adhesion layer, a solder bonding layer above the CrCu layer and a solder top layer. The adhesion layer is either TiW or TiN. A process for fabricating an improved terminal metal consists of depositing an adhesive metallic layer, a layer of CrCu over the adhesive layer and a layer of solder bonding material, over which a solder layer is formed in selective regions and the underlying layers are etched using solder regions as a mask. <MATH>
Patent EP-0734346-B1 (EP)
Inventor: HUDSON SIMON JOHN
IPC: B65D81/32
Filed: 1994-12-14
Granted: 1998-10-07
Abstract: PCT No. PCT/GB94/02735 Sec. 371 Date Aug. 21, 1996 Sec. 102(e) Date Aug. 21, 1996 PCT Filed Dec. 14, 1994 PCT Pub. No. WO95/16621 PCT Pub. Date Jun. 22, 1995A package comprising a plurality of filled sealed containers containing dispensable materials, adjacent containers (20a, 20b) being connected by a joint (40) which comprises a tear means (50) allowing the containers, to be torn open with a single tearing action.
Patent EP-0738209-B1 (EP)
Title: Adjustable throttle with flat channel cross-section
Inventor: GROSS HEINZ DR-ING
IPC: B29C48/08
Filed: 1994-12-02
Granted: 1998-05-06
Abstract: PCT No. PCT/EP94/04015 Sec. 371 Date Jul. 2, 1996 Sec. 102(e) Date Jul. 2, 1996 PCT Filed Dec. 2, 1994 PCT Pub. No. WO95/18711 PCT Pub. Date Jul. 13, 1995The invention relates to an adjustable throttle with which to influence the mass flow within a rectangular flow channel or a flat flow channel with rounded marginal areas. Because of its special design, the throttle has no parting plane perpendicular to the fluid flow direction. The channel height may be modified by this throttle, so that the fluid mass flow may be influenced by changing the local flow channel resistance as a function of its width without creating discontinuities in the flow channel. Because of this continuous change in the geometry of the flow channel, both in the direction of its width and in the flow direction, the whole flow channel is totally free from dead spots.
Patent EP-0731706-B1 (EP)
Inventor: SCHMIDT ALFRED
IPC: A61K/
Filed: 1994-12-02
Granted: 2000-05-17
Abstract: The invention disclosed relates to treating aphthae by applying dimeticone to the afflicted oral mucosa.
Patent EP-0755550-B1 (EP)
Inventor: SEYMOUR JOHN EDWARD
IPC: G08B15/00
Filed: 1995-04-04
Granted: 1998-12-30
Abstract: An alarm unit (20) which conveniently forms part of an alarm system is adapted when in operative condition, and when the alarm system of which it forms part is armed, to be caused by a trigger signal produced by the alarm system to generate an audio and/or visual message advising of activation of the alarm system. Thus, if the alarm system is armed or disarmed erroneously by an authorised user, or if an authorised user inadvertently triggers the alarm system, he will be alerted by the advisory message to take appropriate remedial action.
Patent EP-0790920-B1 (EP)
Inventor: MCKENNA DOUGLAS B
IPC: B01J20/28
Filed: 1995-04-17
Granted: 2003-03-05
Abstract: L'invention concerne un récipient avec un adsorbeur de gaz permettant de respirer en circuit fermé, contenant au moins une feuille ayant à l'intérieur une substance adsorbante et une portion de la feuille espacée grâce à des moyens d'espacement. La feuille est disposée pour que les gaz expirés arrivant de l'entrée, passent à l'intérieur du récipient sensiblement parallèlement à la surface de la feuille. Les feuilles peuvent être formées avec une toile interne disposée entre deux membranes résistantes aux liquides (eau), mais perméables aux gaz et la substance adsorbante peut être placée dans les interstices de la toile. Egalement les feuilles peuvent se présenter sous la forme de feuilles de PTFE expansé poreux ayant une microstructure de noeuds interconnectés par des fibrilles, ladite feuille renfermant la substance adsorbant les gaz. La feuille peut être recouverte sur chaque côté d'une feuille de PTFE poreux expansé. Ce nouveau système permet de bien tenir en place la substance adsorbante à l'intérieur des feuilles en cas de vibrations, d'entrée d'air ou d'eau.
Patent EP-0759852-B1 (EP)
Inventor: BORNHORST KENNETH F JR
IPC: H04N1/047
Filed: 1995-05-03
Granted: 2005-08-10
Abstract: This invention is a system for locating a plurality of engraving heads (68, 68') on an engraver (10) and automatically positioning such heads into a predetermined configuration. A mechanism for positioning the heads (68, 68') includes a lead screw (36) and a drive nut (38) which is rotatable relative to the lead screw (36). Each of the heads (68, 68') includes a rotatable drive nut (38) with a respective motor (40) for rotating the nut (38) whereby the heads (68, 68') are selectively positioned into a predetermined configuration. The heads (68, 68') are mounted on a carriage (26) movable in an axial direction relative to a cylinder (20) to be engraved. The heads (68, 68') are selectively positionable on the carriage (26) and the carriage (26) includes a nut (38) threadably engaged with a lead screw (36) whereby the carriage (26) is driven in an axial direction relative to the cylinder (20) to be engraved. A method for engraving a cylinder (20) includes automatically adjusting a plurality of engraving heads (68, 68') into a predetermined configuration, and engraving a plurality of images onto the cylinder (20).
Patent EP-0766898-B1 (EP)
Inventor: LOBLEY NIGEL
IPC: H04Q3/00
Filed: 1995-06-21
Granted: 1999-02-24
Abstract: A telecommunications network has switching means (12) configured such that a request from a first network termination (10) to establish a communications link with a second network termination is directed to the service processing means (13) which directs the switching means (12) to establish the link. This enables the user terminal (10) to direct service and call setup requests directly to the service processing means (13), the switch (12) not being involved with the call or service request until the service processing means (13) instructs it to participate, thereby minimising the establishment and allocation of resources until it is clear that such resources are required. A call can therefore be validated before any communications links are established, thus potentially offering economies in the operation of the system.
Patent EP-0771179-B1 (EP)
Inventor: LAWIN TIMOTHY PAUL
IPC: A61F2/00
Filed: 1995-06-13
Granted: 2003-08-06
Abstract: An improved biocompatible composition consisting of physiologically stable microparticles carried in a lubricative suspension, solution, other fluid or gel is presented. The composition is intended to be delivered into the body through a small-bore needle, cannula, or catheter and to a tissue site for the purpose of augmenting the tissue site and surrounding area, thereby correcting a defect, filling a void, or strengthening the support structures of the tissue. The particles are a hard, metallic substance and are carbon-coated.
Patent EP-0804565-B1 (EP)
Inventor: BUJARD HERMANN
IPC: C12N15/11
Filed: 1995-06-29
Granted: 2005-09-21
Abstract: Nucleic acid molecules and proteins useful for regulating the expression of genes in eukaryotic cells and organisms are disclosed. The invention provides a transcriptional activator fusion protein which binds to tet operator sequences and stimulates transcription of a tet operator-linked gene in the presence, but not the absence, of tetracycline (or analogue thereof). The invention further provides transcriptional inhibitor fusion proteins which inhibit transcription of a tet operator-linked gene in a regulated manner. In one embodiment, the inhibitor fusion protein binds to tet operator sequences in the absence, but not the presence, of tetracycline (or analogue). In another embodiment, the inhibitor fusion protein binds to tet operator sequences in the presence, but not the absence, of tetracycline (or analogue). The transcriptional activator and inhibitor fusion proteins of the invention can be used in combination to regulate expression of one or multiple tet operator-linked genes. Novel tet operator-containing transcription units which allow for coordinate or independent tetracycline-regulated expression of two or more genes by the transcriptional modulators of the invention are also disclosed. Kits including the components of the regulatory system are also encompassed by the invention. <IMAGE>
Patent EP-0775216-B1 (EP)
Inventor: PETRIK JURAJ
IPC: C12Q1/6806
Filed: 1995-07-26
Granted: 2002-04-03
Abstract: Sondes destinées à l'ARN de VHC, VIH et HTLV et leur utilisation pour la détection et l'extraction de l'ARN.
Patent EP-0720808-B1 (EP)
Inventor: PADOVANI ROBERTO
IPC: H04B7/26
Filed: 1995-07-21
Granted: 2003-10-01
Abstract: A method and apparatus for matching the location of the forward link handoff boundary to the reverse link handoff boundary. A system constant is chosen which defines the product of the received power and the transmitted pilot power at every base station. The reverse link power level is measured at the base station and the forward link power level is compensated for the reverse link loading to maintain the constant product. Thereby the forward link handoff boundary to the reverse link handoff boundary are aligned to the same location.
Patent EP-0778821-B1 (EP)
Inventor: BREAULT GLORIA ANNE
IPC: C07C291/04
Filed: 1995-08-29
Granted: 1999-10-20
Abstract: PCT No. PCT/GB95/02030 Sec. 371 Date Feb. 21, 1997 Sec. 102(e) Date Feb. 21, 1997 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/06822 PCT Pub. Date Mar. 7, 1996The invention provides compounds of formula I: wherein A, B, D, X, R1, and R3 have any of the values defined in the specification, as well as N-oxides thereof, S-oxides thereof, pharmaceutically acceptable salts thereof, and in vivo hydrolizable esters and amides thereof, that are useful to relieve pain. The invention also provides pharmaceutical compositions as well as synthetic and therapeutic methods relating to such compounds.
Patent EP-0721679-B1 (EP)
Inventor: SANDER DIETER
IPC: H01R4/20
Filed: 1995-07-28
Granted: 1999-12-22
Abstract: In a compression-type sleeve (1) for creating a crimped joint with a strand, in particular an electrical conductor, the inner sleeve surface is provided, at least in the ring-zones subject to pressure, with groove-like cavities (5) which extend along the length of the sleeve. The groove-like cavities (5) are of a depth which reduces the thickness of the compression-type sleeve to the extent that longitudinal edges are formed along the cavities (5) when the crimping pressure is applied, and/or are shaped in at least one of the faces of the compression-type sleeve (1) in the form of pressure-relief channels for compressed grease.
Patent EP-0846009-B1 (EP)
Inventor: SMITH ADRIAN E
IPC: A61M/
Filed: 1995-09-15
Granted: 2008-03-05
Abstract: A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.
Patent EP-0785981-B1 (EP)
Inventor: LAPPAS DIMITRIS
IPC: C11D3/32
Filed: 1995-09-29
Granted: 2002-04-10
Abstract: A liquid detergent composition comprising anionic surfactants selected from the group of alkyl alkoxy sulfates and alkyl sulfates, characterized in that said detergent composition further comprises a tertiary amine having formula (1), wherein R1 is C4-C10, preferably C8-C10 alkyl; n is 2-4, preferably n is 3; R2 is C1-C4 or formula (2), whereby x is 1-5, R3 is H or C1-C2 alkyl.
Patent EP-0789788-B1 (EP)
Inventor: LORIMER D ARCY H
IPC: F04B37/16
Filed: 1995-10-30
Granted: 2003-05-02
Abstract: A wafer processing system including a processing chamber, a low pressure pump coupled to the processing chamber for pumping noble and non-noble gases, a valve mechanism coupling a source of noble gas to the processing chamber, an in situ getter pump disposed within the processing chamber which pumps certain non-noble gases during the flow of the noble gas into the chamber, and a processing mechanism for processing a wafer disposed within the processing chamber. Preferably, the in situ getter pump can be operated at a number of different temperatures to preferentially pump different species of gas at those temperatures. A gas analyzer is used to automatically control the temperature of the getter pump to control the species of gasses that are pumped from the chamber. A method for processing a wafer of the present invention includes the steps of placing a wafer within a processing chamber and sealing the chamber, flowing a noble gas into the chamber while simultaneously pumping the chamber with an external low pressure pump and with an in situ getter pump disposed within the chamber which pumps non-noble gases, and processing the wafer within the chamber while the noble gas continues to flow. The method also preferably includes the steps of monitoring the composition of the gas within the chamber and controlling the temperature of the getter material based upon the analysis of the composition.
Patent EP-0789588-B1 (EP)
Inventor: HADDEN JOHN W
IPC: A61P37/00
Filed: 1995-11-16
Granted: 2005-01-19
Abstract: A method of producing a natural nonrecombinant cytokine mixture is disclosed including the steps of immobilizing at least one mitogen in a tissue culture vessel. An isolated population of lymphocytes free of neutrophils and erythrocytes, is suspended in a serum-free media and placed in the vessel. The lymphocytes are cultured, the media removed, and characterized for the yield of cytokines.
Patent EP-0802847-B1 (EP)
Inventor: PETTERSSON AXEL BOERJE
IPC: B60S1/38
Filed: 1995-12-27
Granted: 2000-08-02
Abstract: PCT No. PCT/SE95/01588 Sec. 371 Date Jul. 11, 1997 Sec. 102(e) Date Jul. 11, 1997 PCT Filed Dec. 27, 1995 PCT Pub. No. WO96/21542 PCT Pub. Date Jul. 18, 1996Method for cutting preferably metal reinforced hoses, metal pipes or similar, and a device for utilization of the method, the cutting operation being performed in a known way using a cutting tool, such as a motor driven cutting disc or similar. As an initial step, a single unit (1) is located within and surrounded by the tubeshaped member (2) at with a central position in relation to the point where cutting is intended to be performed, the single unit (1) being arranged to take up sealing contact with the internal surface of the tubeshaped member (2) by at least two separated areas (4, 4') at each side of the cutting point. Cutting is thereafter performed through the tubeshaped member (2) as well as through the surrounded single unit (1), and the separated parts of the surrounded single unit (1) are as a final step pulled out from the tubeshaped member (2) in direction towards the end portions formed by the cutting operation.
Patent EP-0726086-B1 (EP)
Inventor: RAUTSCHEK HOLGER DR RER NAT
IPC: B01D19/04
Filed: 1996-02-09
Granted: 2003-05-02
Abstract: Siloxane-based foam suppressant preparations (A) contg. hydrophobic silica consisting of a mixt. of (a1) commercially available hydrophobic silica and (a2) silica which is rendered hydrophobic in situ. Also claimed is a process for the prodn. of (A).
Patent EP-0813609-B1 (EP)
Inventor: GUT IVO GLYNNE
IPC: C12Q1/6872
Filed: 1996-03-04
Granted: 2004-10-13
Abstract: A method of analysing a nucleic acid by mass spectrometry comprising the steps of: (1) preparing a nucleic acid molecule comprising a negatively charged non-phosphate sugar-sugar linkage; (2) eliminating the charge from all, or up to all but ten, of the sugar-sugar linkages of the said nucleic acid molecule; (3) introducing the said nucleic acid molecule in which the charge has been wholly or partly eliminated as said into a mass spectrometer, and (4) determining the mass of the said nucleic acid molecule. Preferably, the nucleic acid has no or one charge. A method of preparing a nucleic acid molecule containing no or up to ten negative charges and no or up to ten positive charges comprising the steps of (1) synthesising a nucleic acid with a phosphorothioate linkage or a phosphoroselenoate linkage between sugar residues, and (2) reacting the said nucleic acid with an alkylating agent so as to eliminate the charge on the said phosphorothioate linkage or said phosphoroselenoate linkage. The methods are useful for DNA sequencing and mutation analysis, and the nucleic acids are useful to suppress gene expression. <IMAGE>
Patent EP-0817809-B1 (EP)
Inventor: VAN ANTWERP WILLIAM P
IPC: G01N27/327
Filed: 1996-03-25
Granted: 2002-07-31
Abstract: A homogenous polymer composition useful as a membrane for biosensors is disclosed. The polymer composition comprises the reaction products of a diisocyanate, a hydrophilic diol or diamine, and a silicone material. An aliphatic diol or diamine may also be included. Membranes prepared from the composition allow for increasing oxygen permeability and decreased analyte permeability (e.g. glucose). They also possess the necessary physical properties of an outer polymeric biosensor membrane.
Patent EP-0771371-B1 (EP)
Inventor: MCCULLOUGH FRANCIS P
IPC: H01M4/58
Filed: 1996-04-25
Granted: 2000-09-13
Abstract: A flexible, ignition resistant, biregional fiber is disclosed, wherein the fiber is preferably derived from a single homogeneous polymeric precursor composition, said biregional fiber comprising an inner core region of a thermoplastic polymeric composition and a surrounding outer sheath region of a thermoset carbonaceous material. The biregional fiber is particularly characterized by having a ratio of the radius of the core region with respect to the total radius of the fiber (r.R) of from about 1:4 to about 1:1.05, an LOI value of greater than 40, a breaking twist angle of from 4 to 13 degrees, and a bending strain value of from greater than 0.01 to less than 50%. In a further embodiment of the invention, a biregional precursor fiber is disclosed, wherein the biregional precursor fiber is preferably derived from a single homogeneous polymeric composition, and wherein said precursor fiber comprises an inner core region of a thermoplastic polymeric composition and a surrounding outer sheath region of an oxidation stabilized, thermoplastic polymeric composition. The precursor fiber is particularly characterized by having a breaking twist angle of from 17 to 23 degrees. The invention further resides in a method of making the ignition resistant biregional fiber. Preferred end uses for the ignition resistant biregional fibers are disclosed including thermal insulation; flame resistant and fire blocking insulation; blends of the biregional fibers with other natural or polymeric fibers; coated fibers, composites of a polymeric matrix reinforced with the biregional fibers of the invention, electron conductive fibers for battery electrodes, and the like. <IMAGE>
Patent EP-0775584-B1 (EP)
Inventor: HOUKI HIDEAKI
IPC: B41J2/335
Filed: 1996-06-13
Granted: 1999-08-18
Abstract: A method of forming an auxiliary electrode layer for a common electrode pattern in a thermal head. The method comprises the steps of preparing a master substrate (1') which has a common electrode pattern (4) on a surface thereof and accommodates for a plurality of head substrates, forming at least one slit (9) on the master substrate (1') along the common electrode pattern (4), and forming an auxiliary electrode layer (6) on the back surface of the master substrate (1') such that the auxiliary electrode layer (6) extends to be connected electrically with the common electrode pattern (4) through the slit (9). The slit (9) is regulated to have a width of 0.5 mm or more, preferably 0.8 mm or more so as to make an appropriate extent (R), over which the auxiliary electrode layer (6) extends.