baber/WOPTO huggingface dataset:
Patent AU-725693-B2 (AU)
Title: Targeted site specific drug delivery compositions and method of use
Inventor: PORTER THOMAS R
IPC: C12N15/113
Filed: 1997-03-12
Granted: 2000-10-19
Abstract: The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a therapeutic substance. This can allow for lower doses and for improved efficacy with drugs which traditionally reach targeted sites and can result in utility for agents such as oligonucleotides which are plagued with problems in reaching targeted sites in necessary therapeutic levels.
Patent AU-659677-B2 (AU)
Title: HIV immunotherapeutics
Inventor: OHNO TSUNEYA
IPC: A61K39/395
Filed: 1992-08-24
Granted: 1995-05-25
Abstract: The present invention provides monoclonal antibodies that are specifically immunoreactive with an HIV-1 gp120 protein or its precursor gp160 protein comprising the amino acid sequence set out in SEQ ID NO: 1, G-P-G-R, and characterized by their capacity to neutralize, in vitro, the infection of H9 cells by live HIV-1 strains MN and IIIB as determined by reverse transcriptase, p24, MT-2 and syncytium formation assays. Presently preferred antibody NM-01 isolated from mouse/mouse hybridoma A.T.C.C. HB 10726 is fruther characterized by its capacity to mediate complement-dependent virolysis of HIV-1 particles and antibody-dependent cellular cytotoxicity of HIV-1 infected cells. Pharmaceutical compositions of the invention are projected to be useful in the passive immunization treatment of animals, especially humans, susceptible to or infected with HIV-1.
Patent AU-690282-B2 (AU)
Title: A method for storing and retrieving data and a memory arrangement
Inventor: TIKKANEN MATTI
IPC: H04Q3/545
Filed: 1995-06-05
Granted: 1998-04-23
Abstract: PCT No. PCT/FI95/00319 Sec. 371 Date Dec. 6, 1996 Sec. 102(e) Date Dec. 6, 1996 PCT Filed Jun. 5, 1995 PCT Pub. No. WO95/34155 PCT Pub. Date Dec. 14, 1995In methods for storing and retrieving data with a memory arrangement and central databases, a trie data structure is utilized in which the nodes are given unique multidimensional search keys in order to save memory space and to easily store and retrieve data, as a result, the efficiency of storage management will be highly improved.
Patent AU-616224-B2 (AU)
Title: A process for the preparation of optically active 3-demethylmevalonic acid derivatives, and intermediates
Inventor: WESS GUNTHER
IPC: C07D405/06
Filed: 1988-12-07
Granted: 1991-10-24
Abstract: A process for the preparation of optically active 3-de-methylmevalonic acid derivatives, and intermediates A process for the preparation of optically active 3-de-methylmevalonic acid derivatives of the formula I   <IMAGE> I  (3,5-dihydroxy carboxylic acid derivatives) or of the formula II   <IMAGE> II  ( beta -hydroxy lactones) in which R, R1 and Y have the indicated meanings, is described. The invention furthermore relates to aldehydes of the formula XII   <IMAGE> XII  in which M represents the indicated protective groups.  The 3-demethylmevalonic acid derivatives of this invention are useful for lowering cholesterol levels of a host.
Patent AU-700648-B2 (AU)
Title: In situ soil and/or residue remediation system and process using multi-level midspacing measurement
Inventor: PELLETIER MARC-ANTOINE
IPC: B09C1/10
Filed: 1995-06-28
Granted: 1999-01-14
Abstract: PCT No. PCT/CA95/00397 Sec. 371 Date Dec. 24, 1996 Sec. 102(e) Date Dec. 24, 1996 PCT Filed Jun. 28, 1995 PCT Pub. No. WO96/00624 PCT Pub. Date Jan. 11, 1996A process for in situ remediation of contaminated soils and/or residues is disclosed. This process takes advantage of a horizontal radial flow irrigating/draining system and sensors (8) located at midspacing between parallel conduit lines (5) to create an environment propitious to the action of decontaminating agents (plants, microorganisms, salts, acids, bases, buffers, enzymes, substrates, surfactants, etc.). For example, a water-saturated zone may be created, the level of water containing decontaminating agents is raised, maintained and/or lowered, which water-saturated encourage desorption or solubilization of soluble contaminants, by adjusting and controlling all the parameters of reaction (time, temperature, pH, oxygenation, etc.) The process is easily adaptably for many classes of contaminants, including volatile compounds and light non-aqueous phase liquids, by further installing supplementary sets of conduit lines and pumping means at adequate levels. The site may be remedied by alternating gaseous and liquid modes to optimize the conditions of reaction, which alternation is advantageously achieved in a multi-unit arrangement, one unit being in gaseous mode while another is in liquid mode.
Patent AU-778713-B2 (AU)
Title: Nucleic acid isolation from stool samples and other inhibitor-rich biological materials
Inventor: SPRENGER-HAUSSELS MARKUS
IPC: C12Q1/68
Filed: 2001-01-18
Granted: 2004-12-16
Abstract: The invention related to a method for the stabilization, purification or/and isolation of nucleic acids from material samples, in particular, stool samples, which can contain impurities and inhibitors or interfering substances. The invention further relates to a reagent kit for carrying out this method. The basis of the invention is, in particular, a method for purification, stabilization or/and isolation of nucleic acids from material samples, whereby a buffer is added to the sample containing the nucleic acids, with a pH value of 2 to 7, a salt concentration of at least 100 mM, or/and a phenol neutralizing substance. According to the invention, pure nucleic acids which may be amplified can be obtained from faecal samples by a simple method, which are suitable for diagnostic proof of infection, in particular, bacterial or viral infection, or mutation, in particular, for tumor-specific DNA mutations.
Patent AU-759984-B2 (AU)
Title: Doll responsive to audible sounds from a computer or the like
Inventor: GRZSEK ROBERT J
IPC: A63H3/48
Filed: 2001-01-18
Granted: 2003-05-01
Abstract: A doll (10) includes a plurality of movable appendages (12, 13, 14, 15) supported upon a torso (11) and operatively coupled to motor driven gear units (77, 96) to provide movement of the appendages. A controller circuit (41) supported within the doll interior controls the operation of the drive motors (45, 47). Microphones (30, 31) are operatively coupled to the control circuit. A computer (20) is provided with software (24) such as game or other activity software which includes a plurality of audible tone signals operative to cause the computer to output audible tones as instruction for the doll. The controller within the doll includes a decode circuit (43) for converting the audible tones to appropriate movement of the doll's appendages and/or speech or other sounds to be produced by the doll.
Patent AU-673154-B2 (AU)
Title: Air fuel ratio control
Inventor: DAVIS ROBERT MAX
IPC: F02D41/30
Filed: 1993-02-11
Granted: 1996-10-31
Abstract: PCT No. PCT/AU93/00058 Sec. 371 Date Jan. 17, 1995 Sec. 102(e) Date Jan. 17, 1995 PCT Filed Feb. 11, 1993 PCT Pub. No. WO93/16278 PCT Pub. Date Aug. 19, 1993A method of controlling the mass of air and fuel delivered to an internal combustion engine per cylinder, per cycle, by utilizing a unique control algorithm.
Patent AU-619566-B2 (AU)
Title: Aeration system for a liquid-filled basin
Inventor: GOTZ HELMUT
IPC: C02F3/20
Filed: 1989-06-15
Granted: 1992-01-30
Abstract: PCT No. PCT/DE89/00388 Sec. 371 Date Jul. 31, 1990 Sec. 102(e) Date Jul. 31, 1990 PCT Filed Jun. 15, 1989 PCT Pub. No. WO90/08742 PCT Pub. Date Aug. 9, 1990.One or more hoses (10) belong to the ventilation system which through a perforation are constructed at least partially as ventilation hose (60). Each of the hoses is permanently connected with a number of holding devices distributed over its length, which hold the hose (10) from below. The holding devices run in a guide rail (14). The hose (10) is drawn into the empty or liquid-filled basin (10) with a traction device along the guide rail (14) which introduces the tractive force onto the body of the hose and holds it there without prestress.
Patent AU-619322-B2 (AU)
Title: Smoking article
Inventor: SERRANO MARK A
IPC: A24D1/22
Filed: 1989-07-21
Granted: 1992-01-23
Abstract: A smoking article in which a flavored aerosol is generated by heat transfer to a flavor bed (21) from the combustion of a carbon heat source (20) is provided. The article generates substantially no sidestream smoke. The transfer of heat from the heat source to the flavor bed is accomplished by convective and radiative heat transfer.
Patent AU-687737-B2 (AU)
Title: Novel neutrophil inhibitors
Inventor: MOYLE MATTHEW
IPC: C07K16/20
Filed: 1993-05-11
Granted: 1998-03-05
Abstract: Compositions enriched for Neutrophil Inhibitory Factor which inhibit neutrophil activity including adhesion to vascular endothelial cells are provided. Such compositions may comprise a glycoprotein isolated from nematodes. These compositions are useful in the therapy of conditions which involve abnormal or undesired inflammatory responses.
Patent AU-731825-B2 (AU)
Title: Microporous membranes and uses thereof
Inventor: MIKA ALICJA M
IPC: H01M50/417
Filed: 1997-10-17
Granted: 2001-04-05
Abstract: Charged membranes comprise a porous substrate and a cross-linked polyelectrolyte or hydrogel located in the pores of the substrate and are useful in a variety of membrane separation processes including pressure driven membrane separation, diffusion dialysis. Donnan dialysis, electrodialysis, electrochemical synthesis and pervaporation.
Patent AU-615129-B2 (AU)
Title: Dispensing devices powered by hydrogel
Inventor: CURATOLO WILLIAM JOHN
IPC: A61K9/52
Filed: 1990-01-11
Granted: 1991-09-19
Abstract: This invention relates to devices useful for the controlled delivery of one or more beneficial agents to an environment of use. More specifically, this invention concerns such devices which are powered by hydrogel, are powered by hydrogel, comprising a layer made of a mixture of one or more beneficial agents and a hydrogel, a second layer of hydrogel and a coating. This invention also relates to the controlled delivery of one or more beneficial agents to an aqueous environment of use through the use of such hydrogel powered dispensing devices. Also disclosed are methods for the controlled delivery of one or more beneficial agents to an aqueous environment of use which comprises administering to or otherwise placing the devices of this invention in the environment of use.
Patent AU-675804-B2 (AU)
Title: Novel fibronectin receptors
Inventor: RUOSLAHTI ERKKI I
IPC: C12P21/08
Filed: 1993-10-21
Granted: 1997-02-20
Abstract: The present invention provides a substantially pure integrin characterized in that it consists of an  alpha v and a  beta 1 subunit. The receptor binds to fibronectin and GRGDSPK but does not bind to vitronectin. The  alpha v beta 1 receptor can be used to determine the presence of ligands for the receptor.
Patent AU-669572-B2 (AU)
Title: Method for tinting a hydrophilic contact lens
Inventor: AUTEN RICHARD D
IPC: D06P3/34
Filed: 1993-11-04
Granted: 1996-06-13
Abstract: Tinting comprises: (a) providing an unhydrated contact lens; (b) providing a dyestuff soln.; (c) providing a printing block comprising a hydrophilic polymer material contg. a dye complexing agent capable of non-covalently bonding the dyestuff; (d) placing the dyestuff soln. onto the printing block; (e) contacting the unhydrated contact lens and the printing block for a time sufficient to allow the dyestuff soln. to diffuse to the lens; and (f) removing the lens from the printing block.
Patent AU-711934-B2 (AU)
Title: Hybrid yarn and permanent deformation capable textile material produced therefrom, its production and use
Inventor: BAK HENNING
IPC: D03D15/50
Filed: 1996-04-04
Granted: 1999-10-21
Abstract: Hybrid yarn comprises: (A) reinforcing filaments with: (i) an initial modulus of more than 600 (800-25,000, pref. 2000-20,000) cN/tex; (ii) a max. tensile strength of more than 60 (80-220, pref. 100-200) cN/tex; (iii) a max. elongation of 0.01-20 (0.1-7.0 pref. 1-5) %; and (iv) a degree of crimping of 5-60 (12-50, pref. 18-36) %; and (B) thermoplastic matrix filaments with a m.pt. at least 10 (20-100, pref. 30-70) degrees C below the m.pt. of (A). Also claimed are: (i) permanently ductile textile sheet contg. an amt. of hybrid yarn sufficient to have a significant effect on the ductility of the sheet; (ii) fibre-reinforced mouldings; (iii) a process for the prodn. of hybrid yarn from components (A) and (B) in a swirling or blow-texturing system in which at least (A) is introduced with an overfeed of 5-60%; (iv) a process for the prodn. of textile sheet as above (i) by weaving, knitting, laying or matting; and (v) a process for the prodn. of mouldings as above (ii) by forming textile sheet (i) at a temp. above the m.pt. of (B) and below the m.pt. of (A).
Patent AU-758483-B2 (AU)
Title: Targeting pharmaceutical agents to injured tissues
Inventor: HALL FREDERICK L
IPC: C12N1/19
Filed: 1999-07-30
Granted: 2003-03-20
Abstract: The present invention provides new compositions and methods to induce therapeutic angiogenesis locally utilizing a collagen binding domain to target an angiogenesis modulating agents. Fusion polypeptides containing a collagen binding domain linked to an angiogenesis modulating agent are provided, as are nucleic acid sequences encoding the fusion polypeptides. Also included are methods for locally altering circulation by administering a fusion polypeptide consisting of a collagen binding domain linked to an angiogenesis modulating agent, or by administering a nucleic acid sequences encoding the fusion polypeptide. Tissue grafts in which isolated tissue is treated with a fusion polypeptide consisting of a collagen binding domain linked to an angiogenesis modulating agent, or with a nucleic acid sequences encoding the fusion polypeptide are also provided, as are methods of making the grafts.
Patent AU-780986-B2 (AU)
Title: Method for operating a wind power station and wind power station
Inventor: WOBBEN ALOYS
IPC: H02J3/40
Filed: 2001-03-31
Granted: 2005-04-28
Abstract: Power delivered from the generator to the grid is regulated or adjusted as a function of grid frequency.
Patent AU-700413-B2 (AU)
Title: Improved rotary cup infeed
Inventor: MAIN RALPH
IPC: B21D43/16
Filed: 1996-03-22
Granted: 1999-01-07
Abstract: Apparatus for forming elongated metal cans from relatively short cups by utilizing a reciprocating ram to drive the cups one at a time through a die pack, is provided with a continuously rotating feeder that transfers the cups from the exit of a gravity feed chute to a receiving station where each cup is indexed for engagement by the ram as it moves forward in its working stroke. The feeder rotates through one complete revolution for each forward-return cycle of the ram and during each revolution thereof a pocket in the feeder receives a cup from the chute, which cup then moves downstream through a guideway to a receiving station. Prior to being seated in a registry formation at the receiving station, the cup is engaged by a stripper that removes the cup from the feeder pocket. The feeder continues to drive the cup toward the registry formation while the cup is being stripped from the feeder pocket. A tensioner device and a formation on the feeder maintain the cup seated fully on the registry formation during the initial engagement of the cup by the ram while the latter moves forward in its working stroke.
Patent AU-625766-B2 (AU)
Title: The use of naftpidil for the therapy of dysuria in cases of benign prostatic hypertrophy
Inventor: SPONER GISBERT
IPC: A61K31/495
Filed: 1990-06-05
Granted: 1992-07-16
Abstract: The use of 1-(2-methoxyphenyl)-4-[3-(naphth-1-yloxy)- 2-hydroxypropyl]piperazine or the salts thereof for the treatment of dysuria associated with prostate hypertrophy is described.
Patent AU-703400-B2 (AU)
Title: Antagonists of LHRH
Inventor: BOWERS CYRIL Y
IPC: C07K7/23
Filed: 1996-04-26
Granted: 1999-03-25
Abstract: LHRH analogs and congeners with high water solubility have been synthesized. These new analogs had 0%-100% antiovulatory activity at a 0.5  mu g dosage and 0%-80% at 0.25  mu g. The ED50 for histamine release was 30.5  mu g/ml->300  mu g/ml.
Patent AU-754209-B2 (AU)
Title: Process for the production of olefins
Inventor: GRIFFITHS DAVID CHARLES
IPC: C10G11/22
Filed: 1999-09-07
Granted: 2002-11-07
Abstract: A process for the production of olefins from a hydrocarbon comprising the steps of: a) providing a first feed stream comprising a gaseous fuel and an oxygen-containing gas; b) contacting the first feed stream with a first catalyst under conditions so as to produce a product stream and unreacted oxygen; c) providing a second feed stream of hydrocarbon feedstock; and d) contacting the second feed stream, the product stream of step b) and the unreacted oxygen step b) with a second catalyst which is capable of supporting oxidation, thereby consuming at least a part of the unreacted oxygen to produce an olefin product.
Patent AU-625525-B2 (AU)
Title: A method of discontinuous production of l-carnitine by a microbiological process
Inventor: HOEKS FRANS
IPC: C12R1/41
Filed: 1990-07-26
Granted: 1992-07-16
Abstract: The process starts from  gamma -butyrobetaine and/or crotonobetaine.
Patent AU-632148-B2 (AU)
Title: Ceramic material
IPC: C04B35/80
Filed: 1990-07-27
Granted: 1992-12-17
Abstract: The invention relates to composite ceramic materials strengthened by the incorporation of ceramic fibres and to a method of making such materials. A novel composite ceramic material comprises an alumina matrix (11) containing mullite formations (12) formed from a colloidal silica filler and alumina fibres (10), part at least of the mullite growth (12) being on the surface of the fibres (10). The composite ceramic material is made by forming an aqueous slurry containing a dispersion of the fibres, filler, colloidal silica and rheological agents, forming the slurry to the desired shape and firing the product. The ceramic matrix material is particularly suitable for the manufacture of ceramic foam filters.
Patent AU-528670-B2 (AU)
Title: Method
Inventor: LARSON WILLIAM MAINE
IPC: B29D30/08
Filed: 1980-09-02
Granted: 1983-05-05
Abstract: A tire having a pair of bead portions for mounting on a rim, a tread portion radially outward of said bead portions and connecting sidewalls is cast and cured from different liquid elastomer forming materials in a three-stage process. First, the inner layer of the tire is molded of high modulus material on a collapsible core in a mold with an outer shell. Second, the first outer shell is removed and a second outer shell of a second mold is mounted around the core and cast inner layer. The tread portion of the tire is then molded by centrifugal casting from a low modulus material. Third, the sidewalls are molded of low modulus, optionally microcellular, material by injection of the liquid elastomer forming material into the sidewall spaces between the molded inner layer and the second outer shell.
Patent AU-664968-B2 (AU)
Title: Interactive book
Inventor: BURROWS ROGER IAN
IPC: A63H33/38
Filed: 1994-06-14
Granted: 1995-12-07
Abstract: An interactive book or device (100) having a mechanism for generating a plurality of sensory outputs in a manner that maximizes the interaction between the user and the book or device. The interactive book includes function initiators (106) for initiating a unique sensory output that corresponds to a visual indicia (114) on a page of the book (104). A function level selector (108) is coupled to the function initiators (106) that selectively changes a function level and thereby selectively changes the sensory output corresponding to each function initiator (106). Consequently, the number of sensory outputs is increased and thereby enables greater interaction between the user and the book. It also encourages the user to creatively combine the sensory outputs to obtain a cognizable aggregate output. <IMAGE>
Patent AU-707044-B2 (AU)
Title: Transfer set connector with a locking lid and a method of using the same
Inventor: LOH ERIC P
IPC: A61M39/10
Filed: 1996-07-17
Granted: 1999-07-01
Abstract: A connector assembly, preferably for medical use, is provided having a key component and a lid lock component to provide fluid communication between a fluid source and a destination such as a patient. The lid lock component includes a removably lockable lid. The lid is held closed in a locked position by stops located on at least one flexible arm integrally formed and selectively displaceable in the lid lock component. The lid is forced open by a longitudinal key within the key component. The key spreads the flexible arms so that the formerly locked lid is capable of passing through an opening created between the flexible arms to clear the stops. The lid is converted into a position parallel to the length of the lid lock component to provide fluid communication between tubing connected to the lid lock component. The connector assembly can be used for dialysis and the like.
Patent AU-748435-B2 (AU)
Title: Data transfer method and device
Inventor: YAMAMOTO YASUYUKI
IPC: G06F13/36
Filed: 1998-04-22
Granted: 2002-06-06
Abstract: A first bus 11 and a second bus 12 are connected through a bus repeater 13 having a buffer memory, and DMA (Direct Memory Access) controllers 22, 27 are respectively connected to the buses 11 and 12. The bus repeater 13 can issue DMA request to the respective DMA controllers 22, 27, and these DMA requests can be masked by respective CPUs 22, 27. The DMA controller 22 carries out DMA transfer of data on the bus 11 between the DMA controller 22 and the buffer memory within the bus repeater 13, and the DMA controller 27 carries out DMA transfer between the buffer memory and the bus 12. The CPU 22 masks DMA request of the bus repeater 13 to directly access the buffer, thereby making it possible to check DMA function. Thus, debugging of the system for carrying out DMA transfer through buffer between different buses is easily carried out. <IMAGE>
Patent AU-602891-B2 (AU)
Title: 4H-1-benzopyran-4-one derivatives, a process for their preparation and their use as medicaments
Inventor: KATTIGE SAMBA LAXMINARAYAN
IPC: C07F9/553
Filed: 1987-04-10
Granted: 1990-11-01
Abstract: The novel 4H-1-benzopyran-4-one derivatives are used as antiinflammatories, analgesics, immunosuppressants and antiallergics. The present invention relates in particular to novel compounds of the formula I 
<IMAGE>
 in which R1 represents hydrogen, alkyl having 1 to 6 carbon atoms, aryl-C1-C4-alkyl, substituted C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6- cycloalkyl-C1-C4-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, aryl, carboxyl or an aldehyde or COO-C1-C4-alkyl group, R2 represents hydrogen, alkyl having 1 to 6 carbon atoms, nitro, amino, aryl, carboxyl, di-C1-C4- alkylamino, or a halogen, R3 represents C1-C4-alkyl, substituted C1-C4- alkyl, hydroxyl, C1-C4-alkoxy, aryl-C1-C4-alkyl, nitro, amino, a C1-C4- alkyl- or di-C1-C4-alkylamino group or halogen, R4 represents hydrogen, hydroxyl, C1-C4-alkoxy, C1-C4-alkanoyloxy, C1-C4-alkoxycarbonyl, aryloxy, amino or a C1-C4-alkyl- or di-C1-C4-alkylamino group, n represents the integer 0, 1 or 2 and R5 represents hydrogen, C1-C6- alkyl, substituted C1-C6-alkyl, aryl-C1-C4-alkyl, C3-C6-cycloalkyl, C3- C6-cycloalkyl-C1-C4-alkyl, C1-C4-alkanoyl or aroyl, where the aryl group is optionally monosubstituted or polysubstituted phenyl, m denotes an integer between 0 and 3 and n denotes an integer between 0 and 2, and their pharmacologically acceptable acid addition salts.