baber/WOPTO huggingface dataset:
Patent WO-2021150578-A1 (WO)
Title: Fluorescently-labeled f-actin protein biosensors and methods of high-throughput drug discovery
Inventor: COLSON BRETT
IPC: G01N33/68
Filed: 2021-01-20
Abstract: Protein biosensors for drug discovery, such as a high-throughput assay utilizing TR-F to detect the properties of binding proteins (e.g., actin-binding proteins, ABPs) using a fluorescence lifetime plate reader and fluorescent probes. In particular, the present invention is a new use of TR-F technique to rapidly evaluate binding of F-actin (- or + Tm) with cMyBP-C in solution. Changes in labeled actin fluorescence lifetime due to cMyBP-C phosphorylation and/or HCM mutations correlated with binding measured by traditional cosedimentation. The present invention features methods for HTS for identifying molecules that modulate cMyBP-C or cMyBP-C-actin complex.
Patent WO-2021150808-A1 (WO)
Title: Skin diagnostics using optical signatures
Inventor: STRASFELD DAVID B
IPC: A61B5/1455
Filed: 2021-01-22
Abstract: Disclosed techniques include skin diagnostics using optical signatures. A plurality of optical excitation light wavelength bands is scanned on a material sample, wherein the material sample exhibits optical spectral characteristics along the light wavelength spectrum. Excitation response wavelengths emitted by the material sample are captured in response to the plurality of optical excitation light wavelength bands, wherein the capturing is accomplished using an imaging sensor. Output values of a plurality of pixels of an image from the imaging sensor are measured, wherein the image represents excitation response wavelengths captured by the imaging sensor, wherein the measuring detects optical spectral characteristics of the material sample, and wherein the optical spectral characteristics are in response to the plurality of optical excitation light wavelength bands. An output signature indicative of composition of the material sample is generated, wherein the output signature is based on interpreting the output values that were measured.
Patent WO-2021150958-A1 (WO)
Title: Treatment methods using a combination of pantethine and a vanin agonist
Inventor: SCHELLING D CHRISTOPHER
IPC: A61P25/08
Filed: 2021-01-22
Abstract: The present disclosure relates, in part, to methods for treating various disorders, including for example nephropathic cystinosis, primary biliary cirrhosis, lipid metabolism disorders (e.g., hyperlipidemia, dyslipidemia, triglyceridemia), and disorders of the central nervous system (e.g., Huntington's disease, Alzheimer's disease, pantothenate kinase-associated neurodegeneration). In certain aspects, methods provided herein for the treatment of, for example, nephropathic cystinosis, primary biliary cirrhosis, lipid metabolism disorders, disorders of the central nervous system, asthma, and hypertension include administration of a therapeutically effective amount of a combination of pantethine and a vanin agonist or activator.
Patent WO-2022046162-A1 (WO)
Inventor: BEESE LORENA
IPC: C12N15/34
Filed: 2021-01-26
Abstract: The present invention relates to fusion proteins and methods of using the same. Specifically, invention relates to fusion proteins comprising an intein and a DNA polymerase, and methods of using the same for DNA synthesis.
Patent WO-2022169439-A1 (WO)
Title: Connexions sans fil de dispositif électronique
Inventor: CHEN CHUNG-CHUN
IPC: H04W12/062
Filed: 2021-02-02
Abstract: Dans un exemple selon la présente divulgation, un dispositif électronique est décrit. Le dispositif électronique comprend un contrôleur sans fil. Le contrôleur sans fil est destiné à établir une première connexion sans fil entre le dispositif électronique et un dispositif périphérique afin de recevoir un identifiant unique pour un second dispositif électronique. Le contrôleur sans fil est également destiné à établir, sur la base de l'identifiant unique pour le second dispositif électronique, une seconde connexion sans fil entre le dispositif électronique et le second dispositif électronique. Le dispositif électronique comprend un émetteur-récepteur sans fil pour transférer sans fil des données au second dispositif électronique par l'intermédiaire de la seconde connexion sans fil.
Patent WO-2021158558-A1 (WO)
Title: Supine breast ct scanner
Inventor: SHENG KE
IPC: A61B6/00
Filed: 2021-02-02
Abstract: A cone beam CT scanner comprises a receiving section configured to receive a breast of the subject whilst in the supine position, a radiation imaging section comprising an x-ray tube and a detector which face each other and have the receiving section interposed therebetween, and a drive unit operable to move the receiving section to a position suitable for imaging the breast of the subject. A method for breast radiography is also disclosed.
Patent WO-2021167797-A1 (WO)
Title: Soft reset for multi-level programming of memory cells in non-von neumann architectures
Inventor: KAMALANATHAN DEEPAK
IPC: G11C13/00
Filed: 2021-02-04
Abstract: A method for setting memory elements in a plurality of states includes applying a set signal to a memory element to transition the memory element from a low-current state to a high-current state; applying a partial reset signal to the memory element to transition the memory element from the high-current state to a state between the high-current state and the low-current state; determining whether the state corresponds to a predetermined state; and applying one or more additional partial reset signals to the memory element until the state corresponds to the predetermined current state. The memory element may be coupled in series with a transistor, and a voltage control circuit may apply voltages to the transistor to set and partially reset the memory element.
Patent WO-2021236183-A1 (WO)
Title: Removable memory card with efficient card lock mechanism and pads layout
Inventor: PINTO YOSEPH
IPC: G06K19/077
Filed: 2021-02-05
Abstract: A memory card is provided with various pad layouts to prevent a data signal pad from contacting a power contact in a host during insertion and removal of the memory card. The memory card can have a form factor and features that accommodate a relatively-large memory with relatively-high performance and accompanying thermal conditions. An efficient card lock mechanism is also provided.
Patent WO-2022169462-A1 (WO)
Inventor: SIMMONS BRANDON DAVID
IPC: A61M39/10
Filed: 2021-02-08
Abstract: Systèmes et procédés d'utilisation d'un composant adaptateur pour un ensemble d'administration de matériau sous forme de particules afin d'administrer une solution mixte sous forme de particules à un patient, le composant adaptateur comprenant au moins une paire d'orifices de connecteur de dispositif. Chaque orifice de connecteur de dispositif est configuré pour se connecter à un connecteur de ligne d'administration correspondant d'un dispositif d'administration de particules afin de recevoir la solution mixte sous forme de particules. Le composant adaptateur comprend en outre un orifice connecteur de fil de guidage configuré pour se connecter à une unité sac de confinement, l'unité sac de confinement comprenant un fil de guidage qui y est disposé et un orifice connecteur de cathéter configuré pour se connecter à un microcathéter afin d'administrer la solution mixte sous forme de particules au patient. Le fil de guidage est configuré pour se rétracter à l'intérieur de l'unité sac de confinement et s'étendre depuis cette dernière afin de positionner le microcathéter à l'intérieur du patient sans déconnecter au moins l'une de la paire d'orifices de connecteur de dispositif du connecteur de ligne d'administration du dispositif d'administration de particules.
Patent WO-2021178158-A1 (WO)
Inventor: RUSS KEVIN
IPC: E02D37/00
Filed: 2021-02-22
Abstract: According to some embodiments, a light pole replacement system is disclosed. The light pole replacement system comprises a foundation plate to support a replacement light pole, a plurality of anchor tubes, threaded rods, and tension bolt adapters. The plurality of anchor tubes is placed into the ground based on a determined placement of the plurality of anchor tubes. Holes are created in the foundation plate based on a location of the plurality of anchor tubes and the foundation plate is placed over the plurality of anchor tubes with the threaded rods and the tension bolt adapters in the plurality of anchor tubes to couple the foundation plate to the plurality of anchor tubes.
Patent WO-2021174122-A1 (WO)
Inventor: NANDI INDRANIL
IPC: A61M5/14
Filed: 2021-02-26
Abstract: Provided herein are the safety features for radiopharmaceutical infusion system for treatment or diagnostic purpose, wherein infusion system comprises a controller, a source of radiopharmaceutical including other components. The controller is configured to perform automated quality control steps at the start of the system during daily quality control and ensure that system complies to desired technical attributes prior to administration to patients. The quality control steps comprise calibration, breakthrough testing, checking for unauthorized connection and/or malware in the system, network or other connected devices.
Patent WO-2021178865-A1 (WO)
Inventor: TANG HAORAN
IPC: B25J9/00
Filed: 2021-03-05
Abstract: Various embodiments of the technology described herein generally relate to systems and methods for trajectory optimization with machine learning techniques. More specifically, certain embodiments relate to using neural networks to quickly predict optimized robotic arm trajectories in a variety of scenarios. Systems and methods described herein use deep neural networks to quickly predict optimized robotic arm trajectories according to certain constraints. Optimization, in accordance with some embodiments of the present technology, may include optimizing trajectory geometry and dynamics while satisfying a number of constraints, including staying collision-free, and minimizing the time it takes to complete the task.
Patent WO-2021216206-A1 (WO)
Inventor: LIU YUE
IPC: C01B25/42
Filed: 2021-03-08
Abstract: Polyphosphate compositions are produced by a process that includes the steps of continuously introducing a phosphate compound into a polymerization vessel, polymerizing the phosphate compound at a temperature of 250-450 °C for a time period sufficient to form the polyphosphate composition, and continuously discharging the polyphosphate composition from the polymerization vessel. The phosphate compound can be fed to the polymerization vessel in the form of an aqueous slurry containing 5- 50 wt. % of the phosphate compound. Resulting polyphosphate compositions often contain at least 8 wt. % of a polyphosphate and less than 35 wt. % of the phosphate compound.
Patent WO-2021183523-A1 (WO)
Title: Devices for removal of visceral fat, and related systems and methods
Inventor: ANDREW MARK
IPC: A61M1/00
Filed: 2021-03-09
Abstract: Methods of treating a medical condition in a patient include performing a lipectomy of visceral fat to remove a quantity of the visceral fat from the subject. The removal of visceral fat treats the medical condition such that the subject experiences at least a reduction of symptoms of the medical condition.
Patent WO-2021183843-A1 (WO)
Title: Technologies for collecting and virtually simulating circadian lighting data associated with a physical space
Inventor: LILIEN ADAM
IPC: H04N5/225
Filed: 2021-03-12
Abstract: Systems and methods for collecting and analyzing lighting conditions associated with a physical space in order to effect circadian-effective design. According to certain aspects, a data capture machine may include various sensors and components, such as at least one image sensor that captures digital images of a set of luminaires, at least one laser that detects physical objects as well as the location of the data capture machine in the physical space, a detector that collects a set of spectral power distribution (SPD) measurements, and a video capture device that collects images at a set of locations of the physical space. The data capture machine may aggregate the captured information and generate an electronic file that a computing device may use to present a visual representation of the lighting conditions of the physical space. This representation may then enable a lighting designer to evaluate the non- visual impact of illumination, and offer tools to improve the design.
Patent WO-2021188689-A1 (WO)
Title: Accurate dosing of vaporizer content
Inventor: JENNINGS ARIC
IPC: G01F11/02
Filed: 2021-03-17
Abstract: A system and method for the capturing and quantification of active ingredients in vapor content that includes a vaporizer device to produce vapor from material having an active ingredient, capture vapor production data from the vaporizer device (e.g., crucible temperature, air flow rate, use duration, etc.), and collect the vapor for content analysis. A vapor profile management system may generate vapor correlation data by correlating the vapor production data to the analyzed vapor content, in some cases using machine learning techniques. The resulting vapor correlation data may be used with a vaporizer device to provide a desired dose of active ingredient, or inform user of a potentially available remaining dose of active ingredient based on vapor production data.
Patent WO-2022211774-A1 (WO)
Title: Monitoring printing fluids
Inventor: OROPESA FISICA ANA
IPC: B41J29/393
Filed: 2021-03-29
Abstract: Example implementations provide a controller to determine a printing fluid abnormality associated with an ink supply channel of a printer; the controller comprising: an input to receive a signal output by a pressure sensor; the signal being indicative of ink pressure associated with the ink supply channel, and a monitor to determine from a characteristic of the signal the presence of an abnormality in the printing fluid.
Patent WO-2021203060-A1 (WO)
Inventor: VILLALUENGA IRUNE
IPC: G01L1/18
Filed: 2021-04-02
Abstract: La présente invention se rapporte à une composition d'électrolyte hybride comprenant un matériau inorganique conducteur d'ions et une matrice réticulée in situ. L'invention porte également sur des procédés et sur des appareils comprenant de telles compositions.
Patent WO-2021207305-A1 (WO)
Title: Compositions and methods using interferon for treating viral respiratory infections
Inventor: MULYE NIRMAL
IPC: A61K39/00
Filed: 2021-04-07
Abstract: The present disclosure provides pharmaceutical compositions comprising interferons (IFNs), methods of treating or preventing viral respiratory infections in subjects thereof using IFNs thereby reducing viral respiratory infections, symptoms thereof, inflammation, and minimizing virus propagation. In some embodiments, the pharmaceutical compositions may comprise at least one IFN, an aminoquinoline, a corticosteroid, and one or more pharmaceutically acceptable excipients, carriers, or diluents; and optionally at least one therapeutic agent, and methods of use thereof. Another embodiment may be directed to any of the disclosed pharmaceutical compositions, where the pharmaceutical composition is inhalable.
Patent WO-2021211671-A1 (WO)
Title: Detection of a rewind attack against a secure enclave
Inventor: HEARN MICHAEL
IPC: G06F21/55
Filed: 2021-04-14
Abstract: A system is provided for detecting whether an application program executing in a secure enclave of a host computing system may be the target of a rewind attack. The system ensures that state information is consistent with messages that are received. The messages contain current ordering information, previous ordering information, and a related message identifier. When a message is received, the system determines whether the previous ordering information of the message and previous ordering information of the state information associated with the related message identifier are consistent. If not consistent, the system may indicate that a rewind attack is in progress because a malicious actor may have provided an out-of-date version of the state information. If consistent, the system updates previous ordering information of the state information that is associated with the related message identifier based on the current ordering information.
Patent WO-2021212046-A1 (WO)
Title: Techniques for user equipment (ue) dynamically adjusting a non-access stratum (nas) timer in a wireless communication system
Inventor: LOTFALLAH OSAMA
IPC: H04W48/06
Filed: 2021-04-16
Abstract: The present disclosure relates to a user equipment (UE) dynamically adjusting a non-access stratum (NAS) timer. Specifically, the UE may determine operation in a wideband and support of an extended coverage (EC) restriction. The UE may further identify a duration of a non-access stratum (NAS) timer based on determining operation in the wideband and the EC restriction. The UE may further transmit an access request message to a network entity to trigger a mobility management procedure. The UE may further receive an acceptance message from the network entity indicating an unrestricted or restricted status of the EC restriction. The UE may further apply the duration to the NAS timer based on the acceptance message indicating the unrestricted or restricted status of the EC restriction received from the network entity or a history of EC restrictions of a public land mobile network (PLMN) in a defined geographic area.
Patent WO-2022225525-A1 (WO)
Title: Methods and applications of novel amorphous high-k metal-oxide dielectrics by super-cycle atomic layer deposition
Inventor: SUN ZHELIN
IPC: H01L27/12
Filed: 2021-04-22
Abstract: Embodiments of the disclosure relate to articles and transistor structures and methods of preparation and use thereof, including a substrate and an amorphous oxide film overlaying at least a portion of the substrate, where the amorphous oxide film includes a first oxide and a second oxide. The first oxide can include zirconium oxide (ZrO2), hafnium oxide (HfO2) or a combination thereof, the second oxide can include silicon dioxide (SiO2), aluminum oxide (Al2O3), nitric oxide (NO) or combinations thereof. The amorphous oxide film can conformal and have a porosity of less than about 1% and may have a dielectric constant (k) of about 8 to about 28.
Patent WO-2021222380-A1 (WO)
Inventor: MANCOSKY DOUGLAS
IPC: A01H1/06
Filed: 2021-04-28
Abstract: Systems and methods for the treatment of plants, including decarboxylation, photo- oxidation, oxidation and/or combinations thereof, of cannabis and hemp plants and oils for biosynthesizing THCA, CBDA, and CBCA from CBGA are disclosed. A cannabinoid compound solution is fed into a cavitation zone of a controlled cavitation apparatus where the cannabinoid compound solution is subjected to cavitation and interaction with UV light for conversion of the cannabinoid compound solution to form a synthesized cannabinoid THC, CBD, CBC, CBG, CBNA, CBEA, CBLA product, or combinations thereof.
Patent WO-2021226460-A1 (WO)
Title: Immunomodulateurs
Inventor: WANG TAO
IPC: A61P35/00
Filed: 2021-05-07
Abstract: La présente invention concerne de nouveaux peptides macrocycliques qui inhibent l'interaction protéine/protéine PD-1/PDL1 et PD-L1/CD80, et sont par conséquent utiles pour l'amélioration de diverses maladies, y compris le cancer et les maladies infectieuses.
Patent WO-2021231334-A1 (WO)
Title: Electrically isolating baffle for horticulture grow light
Inventor: VILGIATE ANTHONY WENDELL
IPC: F21V29/60
Filed: 2021-05-10
Abstract: A horticulture grow light includes: an emitter array; a heatsink on one side of the emitter array; a driver electrically connected to the emitter array; and an electrically isolating baffle connected to the heatsink. The baffle includes: an air funnel; a plurality of driver panels respectively connected at opposite sides of the air funnel and extending toward the heatsink; and a plurality of support panels respectively connected to the driver panels and extending toward the heatsink. A first active airflow section is formed between inner surfaces of the driver panels and inner surfaces of the support panels, and second active airflow sections are respectively formed on either side of the first active airflow section and between the inner surfaces of the driver panels and outer surfaces of the support panels.
Patent WO-2021231448-A1 (WO)
Title: Systems and methods for creating hydrocarbon wells
Inventor: AYUB JIBRAN
IPC: E21B43/30
Filed: 2021-05-11
Abstract: Provided are embodiments that include identifying candidate well parameters for a hydrocarbon well that include a location, a well production rate and candidate horizontal wellbore lateral lengths for the well, conducting simulations of hydrocarbon wells located at the location and having lateral lengths corresponding to the candidate horizontal wellbore lateral lengths and operating at the well production rate to determine a gas breakthrough productivity indexes (GBPIs) for the simulated wells, determining (based on the GBPIs) a relationship of GBP! to horizontal wellbore lateral length, determining (based on the relationship) an optimized horizontal wellbore lateral length for the production rate, and developing the well based on the optimized horizontal wellbore lateral length.
Patent WO-2021237189-A1 (WO)
Title: Sole structure for article of footwear
Inventor: DURFLINGER NATE
IPC: A43B13/14
Filed: 2021-05-22
Abstract: An article of footwear includes an upper extending from a first end in a forefoot region to a second end in a heel region. The article of footwear also includes a sole structure attached to the upper and including a posterior end extending beyond the second end of the upper. The sole structure includes a bladder having a portion disposed between the second end of the upper and the posterior end of the sole structure.
Patent WO-2021242705-A1 (WO)
Title: System and method for solar-powered desalination and water purification
Inventor: SOLIMAN SHERIF
IPC: C02F1/14
Filed: 2021-05-24
Abstract: A novel solar-powered desalination and water purification system is disclosed herein. The system includes a nanofiber-impregnated graphene aerogel, an untreated water source, a water collection surface, and a purified water storage container. A novel photocatalytic nanofiber-impregnated graphene aerogel for desalination and photodegradation of contaminants for use in the disclosed system is also disclosed herein. The nanofiber-impregnated graphene aerogel exhibits excellent hydrophilicity, thermal insulation, and photodegradation capability, and allows for efficient solar-powered evaporation of water. The introduction of photocatalytic nanofibers into the graphene aerogel allows effective interfacial evaporation and in situ photodegradation of contaminants. The rate of water evaporation is preferably greater than 1.3 gal/ft2 per day, and the contaminant removal is preferably greater than 90%. A method of desalinating and purifying water using the disclosed system is also disclosed herein.
Patent WO-2022015543-A1 (WO)
Title: Roller sealing machines having wide backing rollers
Inventor: LOMASCOLO CHRISTIAN
IPC: B29C65/00
Filed: 2021-07-07
Abstract: A system is capable of advancing and sealing a web of inflatable containers. The system includes a sealing roller that includes a sealing element located around a circumferential surface of the sealing roller. The system also includes a backing roller positioned with respect to the sealing roller to form a nip between a circumferential surface of the backing roller and the circumferential surface of the sealing roller. When the longitudinal edge of the web is located in the nip, the sealing roller and backing roller counterrotate to advance the web. The circumferential surface of the backing roller extends axially farther into the web than the circumferential surface of the sealing roller extends axially into the web such that backing roller contacts the web at a transverse location that is farther away from the longitudinal edge of web than the sealing roller contacts the web.