baber/WOPTO huggingface dataset:
Patent CA-3091146-A1 (CA)
Title: 17.beta.-hydroxysteroid dehydrogenase type 13 (hsd17b13) irna compositions and methods of use thereof
Inventor: HINKLE GREGORY
IPC: C12N15/113
Filed: 2019-03-20
Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the HSD17B 13 gene, as well as methods of inhibiting epression of HSD17B13, and methods of treating subjects that would benefit from reduction in expression of HSD17B13, such as subjects having a HSD17B13-associated disease, disorder, or condition, using such dsRNA compositions.
Patent CA-3093541-A1 (CA)
Inventor: TEZAWA KAZUHIRO
IPC: B23C5/12
Filed: 2019-04-11
Abstract: A machining cutter (1) for tip dressing is provided with a rotating holder (5) and a machining plate (2). The machining plate (2) is provided with a cutting edge part (2d) that is formed at a portion connecting a rake surface part (2a) and a flank surface part (2b), the cutting edge part (2d) extending in a direction that intersects a rotational axis (C1). A plurality of recessed groove parts (2e) are formed at prescribed intervals in the flank surface part (2b) in a direction that intersects the rotational axis (C1), the recessed groove parts (2e) extending so as to separate from the cutting edge part (2d) along a circumferential direction about the rotational axis (C1) from a position approaching the cutting edge part (2d).
Patent CA-3097394-A1 (CA)
Title: Appareil d'outil a main avec poignee ergonomique adaptative
Inventor: WINK CHERIE YVETTE
IPC: A61C3/00
Filed: 2019-04-18
Abstract: L'invention concerne un appareil d'outil à main permettant d'obtenir une partie poignée ergonomique adaptative et allongée. Dans au moins un mode de réalisation, la partie poignée fournit une paire d'extrémités de poignée opposées. Au moins l'une des extrémités de poignée fournit une partie instrument. Un au moins un noyau pliable est positionné entre les extrémités de poignée, le ou les noyaux pouvant être sélectivement pliés en une variété de configurations de forme souhaitées, et maintenant sensiblement ces configurations de forme jusqu'à ce que le noyau soit intentionnellement plié en une configuration de forme souhaitée différente. Par conséquent, la partie poignée est capable de se conformer ergonomiquement à une main d'un utilisateur tout en décalant le poids de l'appareil et encourageant le positionnement correct de la partie instrument pendant l'utilisation de l'appareil, indépendamment de la procédure spécifique à effectuer à l'aide de l'appareil.
Patent CA-3098803-A1 (CA)
Title: A process for drying fruits and vegetables
Inventor: Guo Shi Ning
IPC: A23B7/02
Filed: 2020-11-12
Abstract: A process for drying fruits and vegetables to achieve high throughput while to keep process temperature low to avoid flavor and nutrition loss is disclosed. The invented process is composed of the following steps: 1) Convert the fruit or vegetable to liquid (juice) and solid portions (pulp) through a few steps so that both portions can be easily processed in large throughput due to fluidity. 2) Pre-treat the two portions separately. 3)Mix the 2 portions and prepare in various parameters, i.e. temperature, moisture, proportion, sweetness, etc. 4) Load the prepared mixture into a vacuum microwave drying chamber through control valves. In the vacuum microwave drying chamber, the mixture will be dried quickly due to its puffiness and uniformity which are critical to vacuum microwave dehydrating process. 5)The dried product will be discharged from the vacuum microwave chamber through a continuous discharging system.
Patent CA-3100769-A1 (CA)
Inventor: BASSAN DANIELE
IPC: F27B9/36
Filed: 2020-11-25
Abstract: A method for moulding a sheet (L) into a component of complex shape having areas with different mechanical properties, particularly a motor-vehicle component. The method involves a first heating step of the sheet (L) carried out by means of a kiln (1), prior to forming the component. The kiln (1) comprises a main body with a roller shape (3), having a plurality of sectors (4) extending along a radial direction with respect to a longitudinal axis (X) of the roller body (3). The sectors (4) are configured to each receive a sheet (L), so that the main body with a roller shape (3) is arranged to simultaneously carry a plurality of sheets (L). The kiln (1) further comprises a plurality of heating elements (5) incorporated in said roller-shaped main body (3), so as to heat the sheets (L) in contact with the roller body (3). The kiln (1) further comprises at least one electronically-controlled drive motor, arranged to rotate the roller-shaped main body (3) around the longitudinal axis (X) of the kiln (1), so as to vary the position of the sectors (4) with respect to the inlet and outlet ports (6, 7). The method also includes an additional heating step following extraction of the sheets (L) from the kiln (1), wherein the sheets (L) are locally heated only at one area, so as to obtain sheets (L) with areas heated to different temperatures.
Patent CA-3102400-A1 (CA)
Title: Image sensor circuitry for reducing effects of laser speckles
Inventor: JOHANNESSON MATTIAS
IPC: H04N13/271
Filed: 2020-12-11
Abstract: Image sensor circuitry (900; 1000) comprising an image sensor and method for supporting reduction of laser speckle effects in a digital image. Per each pixel position (x, y) of at least a subregion of the image sensor, the image sensing circuitry:  Assigns (501) to said pixel position (x,y) a predefined pixel window (w) comprising said pixel position (x,y) and one or more of its closest neighboring pixel positions. Obtains (502) first pixel values (v1) for each pixel (pw) located within said predefined pixel window (w), said first pixel values (v1) resulting from the same exposure and corresponding to sensed light from this exposure. Combines (503) the obtained first pixel values (v1) into a single, second pixel value (v2) according to a predefined combination function. The digital image is provided based on the second pixel values.
Patent CA-3103925-A1 (CA)
Title: A functionalized sensor for detection of biomarkers
Inventor: NAWANA NAMAL
IPC: G01N33/58
Filed: 2019-05-24
Abstract: In one aspect, the present teachings provide a sensor for detecting troponin, e.g., cardiac troponin in a patient's blood, that relies on an electronic signature generated via interaction of troponin with an anti-troponin antibody. More specifically, as discussed in more detail below, such a sensor can include a graphene layer disposed on an underlying substrate, where the graphene layer has been functionalized with an anti-troponin antibody. The interaction of troponin in a sample, e.g., a patient's blood, with the anti-troponin antibody coupled, e.g., anchored, to the graphene substrate, can modulate an electronic property of the underlying graphene layer. The modulation of the electronic property of the graphene layer can be measured and used to identify, and in some embodiments quantify, troponin in the sample.
Patent CA-3103950-A1 (CA)
Title: Dual-output microelectromechanical resonator and method of manufacture and operation thereof
Inventor: XEREAS GEORGE
IPC: G01K7/00
Filed: 2019-06-28
Abstract: There is provided a dual-output microelectromechanical system (MEMS) resonator. The MEMS resonator can be operated selectively and concurrently in an in-plane mode of vibration and an out-of-plane mode of vibration to obtain respectively a first electrical signal having a first frequency, and a second electrical signal having a second frequency being less than the first frequency. The first and second electrical signals are mixed to obtain a third electrical signal having a third frequency, where the third frequency is proportional to a temperature of the MEMS resonator. The temperature is determined based on the third frequency. Values of the first and second frequencies can be adjusted based on the determined temperature to compensate for frequency deviations due to temperature deviations. There is also provided methods and systems for determining the temperature of the dual-output MEMS, for compensating the frequency, and a method of manufacturing the dual-output MEMS.
Patent CA-3104104-A1 (CA)
Inventor: ROY KINKINI
IPC: B01D71/30
Filed: 2019-06-26
Abstract: The disclosed technology relates to flat sheet porous membranes prepared from a dope solution containing a polymer of vinyl chloride, such as chlorinated polyvinyl chloride.
Patent CA-3106170-A1 (CA)
Title: Apmv et utilisations associees pour le traitement du cancer
Inventor: GARCIA-SASTRE ADOLFO
IPC: C12N7/00
Filed: 2019-07-12
Abstract: Selon un aspect, la présente invention concerne des paramyxovirus aviaires (APMV) naturels et produits par recombinaison (par exemple, une souche d'APMV-2, APMV-3, APMV-4, APMV-6, APMV-7, APMV-8 et APMV-9) et des utilisations de tels APMV pour le traitement du cancer. En particulier, l'invention concerne des méthodes de traitement du cancer consistant à administrer à un sujet qui en a besoin une souche d'APMV-4 naturelle ou produite par recombinaison. Selon un autre aspect, la présente invention concerne un APMV recombiné comprenant un génome encapsidé, le génome encapsidé comprenant un transgène. En particulier, l'invention concerne un APMV recombiné (par exemple, APMV-2, APMV-3, APMV-4, APMV-6, APMV-7, APMV-8, et APMV-9). Selon un autre aspect, l'invention concerne des méthodes de traitement du cancer consistant à administrer à un sujet qui en a besoin un APMV recombiné (par exemple, APMV-2, APMV-3, APMV-4, APMV-6, APMV-7, APMV-8 et APMV-9), l'APMV recombiné comprenant un génome encapsidé comprenant un transgène. En particulier, l'invention concerne des méthodes de traitement du cancer consistant à administrer à un sujet qui en a besoin un APMV-4 recombiné, l'APMV-4 recombiné comprenant un génome encapsidé comprenant un transgène. Selon des aspects spécifiques, l'utilisation de sérotypes d'APMV autres que l'APMV-1 (tels que décrits dans la description, en particulier l'AMPV-4) pour traiter le cancer se base, en partie, sur des activités anti-tumorales in vivo similaires ou améliorées par comparaison avec une souche NDV LaSota-L289A oncolytique.
Patent CA-3106357-A1 (CA)
Inventor: ZEC DRAGAN
IPC: G02B6/00
Filed: 2020-04-16
Abstract: : A wear sensing liner for a comminution appara-tus. The wear sensing liner comprising: a liner body comprising;  a wear surface side defining a wear surface; and an opposed, op-eratively rear surface side; and at least one sensor carried by the liner body. The at least one sensor being carried by the liner body to sense wear of the wear surface side of the liner body. The at least one sensor being configured to degrade in response to wear of the wear surface side of the liner body and to output a signal representative of the wear of the wear surface side of the liner body.
Patent CA-3107651-A1 (CA)
Inventor: YOSHIMURA MINA
IPC: A21D13/80
Filed: 2019-07-26
Abstract: L'invention concerne un procédé de production de confiseries cuites comprenant : une étape de préparation d'une pâte pour confiseries cuites, la pâte comprenant un composant (A), qui est un matériau granulaire qui contient 75 % en masse ou plus d'amidon, le matériau granulaire comprenant de 3 à 45 % en masse (inclus) d'un amidon de faible poids moléculaire qui a une teneur en amylose de 5 % en masse ou plus en tant qu'amidon, et étant tel que le poids moléculaire de pic de l'amidon de faible poids moléculaire est de 3 × 103 à 5 × 104 (inclus) et le degré de gonflement dans l'eau froide du matériau granulaire à 25 °C est de 5 à 20 (inclus), la teneur en humidité (à l'exclusion de l'humidité dans une matière première de poudre) étant de 18-55 % en masse (inclus) ; et une étape de chauffage de la pâte, le procédé étant tel que, lors de l'étape de préparation de la pâte pour confiseries cuites, la quantité de mélange du composant (A) est de 0,01-0,24 (inclus) en termes de rapport massique par rapport au taux d'humidité.
Patent CA-3108444-A1 (CA)
Title: Channel monitoring and shared use of a wireless channel
Inventor: MUKHERJEE AMITAV
IPC: H04W72/12
Filed: 2019-08-13
Abstract: According to one configuration, a wireless network includes first wireless stations and second wireless stations. The first wireless stations and second wireless stations support different wireless communication protocols and compete to use a wireless channel. Via monitoring of a control channel generated by a management resource associated with at least the first wireless stations, a given wireless station of the second wireless stations determines availability (unused time slots, frames, etc.) of the wireless channel via monitoring of the wireless channel itself and/or a control channel. In the latter instance, the control channel indicates scheduled usage of the shared wireless channel by at least the first wireless stations. In accordance with the scheduled usage as indicated by the control channel, the given wireless station transmits over the wireless channel during free slots, times, gaps, etc., to communicate with a remote wireless station of the second wireless stations.
Patent CA-3112029-A1 (CA)
Inventor: COLLIN SIDNEY
IPC: A61F5/00
Filed: 2019-09-13
Abstract: Devices used to cue a user to take a step when experiencing a walking disorder, such as a freezing of gait episode, are disclosed. The devices are configured to cue the user with a visual and/or audible cue. The devices include an activation module and a cueing module. The cueing module includes a metronome and a laser light source. The devices are mounted on an assistive mobility device or on the user.
Patent CA-3112245-A1 (CA)
Title: A blower having speed regulation
Inventor: ZHOU PENG
IPC: A01G20/47
Filed: 2021-03-16
Abstract: A blower includes: a housing; a fan; a motor; and a speed regulator assembly including a switch for controlling the motor operation, a control member and an actuating member both enabled to control the switch. The actuating member can move between an off state and an on state, the actuating member can move to a predefined limit position, the rotational speed of the motor corresponding to the predefined limit position is a predefined rotational speed. When the actuating member is in the off state, the motor stops running. When the actuating member is in the on state, the motor rotates. The control member has at least a first control state and a second control state. In the second control state, the motor runs at a maximum rotational speed. In the first control state, the motor runs at an intermediate speed lower than the maximum rotational speed.
Patent CA-3113168-A1 (CA)
Title: Systems and methods for enhancing and facilitating access to specialized data
Inventor: MARTIN RUSSELL W
IPC: G06Q10/00
Filed: 2021-03-24
Abstract: A novel approach to facilitating access to valuable actionable content from a multi-tenant database involves system generated ranking of connection content with associated data retrieval methods and systems, utilizing "connector" scores to rank responsive content.  The system "learns"  how to optimize retrieving and ranking high value actionable content with experience; and applies optimized scoring parameters to enhance future operations. The computer platform is greatly improved by delivering actionable content that is immediately translated into critical operations and tasks recommended by the system to support transactions for the User.
Patent CA-3115022-A1 (CA)
Title: Recepteurs de lymphocytes t specifiques diriges contre des epitopes de la proteine myd88l265p mutante en vue d'une therapie adoptive par lymphocytes t
Inventor: PEZZUTTO ANTONIO
IPC: C07K14/725
Filed: 2020-01-21
Abstract: La présente invention se rapporte au domaine de l'immunothérapie, en particulier la thérapie adoptive par lymphocytes T ou la thérapie génique anti-cancéreuse du récepteur des lymphocytes T (TCR). L'invention concerne un acide nucléique codant pour au moins une construction de chaîne alpha ou bêta de TCR d'une construction TCR capable de se lier de manière spécifique à un peptide MYD88 L265P de SEQ ID NO : 2 dans un contexte de HLA-B* 07 : 02 ayant une avidité élevée audit complexe peptide/HLA. L'invention concerne également des protéines correspondantes et des cellules hôtes, de préférence des lymphocytes T CD8+, ainsi que l'utilisation médicale desdits acides nucléiques, protéines ou cellules hôtes, en particulier, dans le diagnostic, la prévention et/ou le traitement d'un cancer exprimant MyD88 L265P tel qu'un lymphome non hodgkinien choisi dans le groupe comprenant un lymphome diffus à grandes cellules B (DLBCL), par exemple, DLBCL de type cellule B activée (ABC-DLBCL) ou pCNS DLBCL, DLBCL cutané, DLBCL de type leg ou DLBCL testiculaire ; lymphome lymphoplasmacytique (LPL), par exemple, Waldenstrom macroglobulinémie (WM) ; et la gammopathie monoclonale IgM (IgM MGUS).
Patent CA-3115616-A1 (CA)
Title: Separation apparatus and method; apparatus and method for bringing articles in a layer
Inventor: REM PETER CARLO
IPC: B07C5/02
Filed: 2019-10-07
Abstract: A separation apparatus is disclosed, comprising: a layerizer arranged to bring a group of particles in a layer on a transport surface with a constant spatial relation of the particles relative to each other in the layer; an identifier arranged to identify particles in the group of particles that have a specific property; a separator arranged to separate the particles in the group based on a difference in affinity between the particles and the separator; an affinity modifier arranged to modify said affinity for identified particles relative to non- identified particles in the group. The layerizer comprises a recirculating transport surface on which the particles of the layer are carried. The transport surface is arranged to move along a transport trajectory as a rigid plane. Further, a method for separation of particles from a group of particles is disclosed.
Patent CA-3117383-A1 (CA)
Title: Systeme portable pour analyser une population microbienne dans un fluide
Inventor: WHALEN PATRICK ANDREW
IPC: G01N1/00
Filed: 2019-12-13
Abstract: La présente invention concerne un système et un procédé qui peuvent être utilisés pour tester des échantillons d'eau pour mesurer l'ATP et/ou estimer une population microbienne, par exemple au moyen d'un dosage basé sur l'adénosine triphosphate (ATP). Le système comprend un dispositif qui est utilisé en combinaison avec des cartouches à usage unique ou jetables. La cartouche reçoit l'échantillon d'eau et est préchargée avec un ou plusieurs réactifs. Le dispositif reçoit la cartouche et contient des dispositifs physiques, électroniques et/ou mécatroniques qui interagissent avec la cartouche. Une ou plusieurs actions telles que le dosage, le mélange et le transport sont effectuées automatiquement par des éléments du dispositif et/ou de la cartouche. Un capteur dans le dispositif mesure la lumière produite dans la cartouche à partir d'une réaction avec l'ATP dans l'échantillon d'eau. Facultativement, la cartouche contient en outre une quantité préchargée d'ATP, qui est utilisée pour fournir une référence interne ou une mesure d'étalonnage.
Patent CA-3118534-A1 (CA)
Title: Dermal skin protectant and carrier
Inventor: LATTA MARK A
IPC: A61P31/12
Filed: 2019-11-05
Abstract: A dermal skin protectant and carrier comprising a combination of two different viscosity dimethicone components, wherein the difference between the two different viscosity dimethicone components is about 2.0 million cP or greater; and comprising at least one active ingredient.
Patent CA-3118547-A1 (CA)
Title: Techniques for encoding a media title via multiple encoders
Inventor: KATSAVOUNIDIS IOANNIS
IPC: H04N21/854
Filed: 2019-11-01
Abstract: In various embodiments, a subsequence-based encoding application generates subsequences based on a source sequence associated with a media title. The subsequence-based encoding application then encodes both a first subsequence and a second subsequence across each of multiple configured encoders and at least one rate control value to generate, respectively, a first set of encoded subsequences and a second set of encoded subsequences. Notably, each configured encoder is associated with a combination of an encoder and a configuration, and at least two configured encoders are different from one another. Subsequently, the subsequence-based encoding application generates encoded media sequences based on the first set of encoded subsequences and the second set of encoded subsequences. Finally, the application selects a first encoded media sequence from the encoded media sequences based on a first target value for a media metric to subsequently stream to a first endpoint device during playback of the media title.
Patent CA-3120990-A1 (CA)
Inventor: DELZER WESTON
IPC: A01M31/00
Filed: 2021-06-03
Abstract: The present disclosure is directed to a game call that can be used to attract, mimic, or communicate with game animals. The game call comprises a plurality of components including an insulating component comprising heat insulating properties. The insulating component is disposed in a location on the game call that provides insulation, in particular, to critical components located in interior portions of the game call. The insulating part may provide insulation to interior parts of the game call including reeds and other critical interior parts of the game call.
Patent CA-3121554-A1 (CA)
Inventor: WELKER MATTHIAS
IPC: C09C3/08
Filed: 2020-02-11
Abstract: La présente invention concerne un produit à base de matériau de charge traité en surface comprenant un matériau de charge contenant au moins un composé à fonction époxy comportant un ou plusieurs groupes époxy et/ou produits de réaction associés, un procédé de préparation dudit produit à base de matériau de charge traité en surface, une composition de polymère contenant au moins une résine polymère et de 1 à 70 % en poids, sur la base du poids total de la composition de polymère, dudit produit à base de matériau de charge traité en surface, un article polymère comprenant ledit produit à base de matériau de charge traité en surface et/ou la composition de polymère, ainsi que l'utilisation du produit à base de matériau de charge traité en surface pour réduire la dégradation des propriétés mécaniques dans un article polymère comprenant le produit à base de matériau de charge traité en surface lorsqu'il est exposé à une lumière UV.
Patent CA-3121781-A1 (CA)
Title: Gene-editing systems for editing a cystic fibrosis transmembrane regulator (cftr) gene
Inventor: WEINBERG MARCO
IPC: C12N15/113
Filed: 2019-12-05
Abstract: Described herein are highly efficient gene-editing systems comprising a nuclease, a guide RNA, and/or a donor template and uses thereof for editing a cystic fibrosis transmembrane regulator (CFTR) gene either in vitro or in vivo.
Patent CA-3123185-A1 (CA)
Inventor: MAEKAWA TAKASHI
IPC: G08G1/00
Filed: 2019-12-12
Abstract: Il est décrit un système de gestion des véhicules de transport comprenant : une unité d'acquisition de données tridimensionnelles qui acquiert des données tridimensionnelles d'un site de travail; une unité de génération d'itinéraire bidimensionnel qui génère un itinéraire bidimensionnel pour un véhicule de transport sur un plan bidimensionnel réglé à un site de travail; et une unité de génération d'itinéraire tridimensionnel qui génère un itinéraire tridimensionnel pour le véhicule de transport à partir de l'itinéraire bidimensionnel, d'après les données tridimensionnelles.