baber/WOPTO huggingface dataset:
Patent ES-2216350-T3 (ES)
Title: Composiciones farmaceuticas que contienen farmacos biciclicos micronizados.
Inventor: DUMPLETON DAVID ROBERT
IPC: A61P25/28
Filed: 1998-12-14
Granted: 2004-10-16
Abstract: Una composición farmacéutica que comprende un compuesto de Fórmula I o Fórmula II posteriores en forma de partículas, teniendo dicha composición una distribución de tamaños de partículas monomodal tal que el valor mediano del diámetro medio volumétrico está dentro del intervalo de 350 a 700 mm, típicamente donde no más de un 10% de las partículas tiene un diámetro volumétrico de 280 nm o por debajo, y no menos de un 90% de las partículas tiene un diámetro volumétrico de 2000 nm o por debajo: **(fórmula)**en la que: o bien Y es N y R2 es hidrógeno, o Y es C-R1 en donde: o bien uno de R1 y R2 es hidrógeno y el otro se selecciona entre la clase de hidrógeno, cicloalquilo C3-8, alquilo C1-6 opcionalmente interrumpido por oxígeno o sustituido con hidroxi, alcoxi C1-6 o aminocarbonilo sustituido, alquil C1-6-carbonilo, alcoxi C1-6-carbonilo, alquil C1-6-carboniloxi, alcoxi C1-6, nitro, ciano, halo, trifluorometilo, CF3S o un grupo CF3-A-, en el que A es -CF2-, -CO-, -CH2- o CH(OH), trifluorometoxi, alquil C1-6-sulfinilo, alquil C1-6sulfonilo, alcoxi C1-6-sulfinilo, alcoxi C1-6-sulfonilo, arilo, heteroarilo, arilcarbonilo, heteroarilcarbonilo, arilsulfinilo, heteroarilsulfinilo, arilsulfonilo, heteroarilsulfonilo, en los que cualquier resto aromático está opcionalmente sustituido, alquil C1-6-carbonilamino, alcoxi C1-6-carbonilamino, alquil C1-6-tiocarbonilo, alcoxi C1-6-tiocarbonilo, alquil C1-6-tiocarboniloxi, 1-mercapto-alquilo C2-7, formilo o aminosulfinilo, aminosulfonilo o aminocarbonilo, estando opcionalmente sustituido cualquier resto amino con uno o dos grupos alquilo C1-6 6 o alquil C1-6-sulfinilamino, alquil C C1-6sulfonilamino, alcoxi C1-6-sulfinilamino o alcoxi C1-6-sulfonilamino, o etilenilo terminalmente sustituido con alquil C1-6-carbonilo, nitro o ciano, o -C(alquil C1-6)NOH o -C(alquil C1-6)NNH2, o uno de R1 y R2 es nitro, ciano o alquil C1-3-carbonilo y el otro es metoxi o amino opcionalmente sustituido con uno o dos alquilo C1-6 o alcanoilo C217; uno de R3 y R4 es hidrógeno o alquilo C1-4 y el otro es alquilo C1-4 o R3 y R4 conjuntamente son polimetileno C2-5; R5 es alquil C1-6-carboniloxi, benzoiloxi, ONO2, benciloxi, feniloxi o alcoxi C1-6 y R6 y R9 son hidrógeno o R5 es hidroxi y R6 es hidrógeno o alquilo C1-2 y R9 es hidrógeno; R7 es fluorofenilo; R8 es hidrógeno o alquilo C1-6; siendo trans el grupo R8-N-CO-R7 respecto al grupo R5; y X es oxígeno o NR10 en donde R10 es hidrógeno o alquilo C1-6; y **(fórmula)** en la que: o bien Y es N y R2 es hidrógeno, o Y es C-R1.
Patent ES-2235422-T3 (ES)
Inventor: HAAS PETER DR
IPC: C08K7/10
Filed: 1999-11-16
Granted: 2005-07-01
Abstract: Reinforced polyurethane-urea elastomers with an isocyanate index of 80-120 are obtained by reacting a polyol component with a functionality of 4-8 (containing aromatic diamine, reinforcing material and catalyst) and an isocyanate prepolymer with a functionality of 3-8, based on a polyol which provides 10-90 mol% of the urethane content of the product. A process for the production of polyurethane-urea (PU/U) elastomers with urea and urethane contents of 70-95 and 5-30 mol% respectively (based on mol% NCO equivalent), by reacting component (A) comprising (A1) aromatic diamines with at least one alkyl substituent in an ortho position to an amino group, (A2) aliphatic polyether- and/or polyester-polyol(s) of mol. wt. 500-18000 with hydroxyl and/or prim. amino groups, (A3) a reinforcing material and optionally (A4) known catalysts or additives with component (B) consisting of (B1) a liquefied polyisocyanate or polyisocyanate mixture of the diphenylmethane series and (B2) polyether- and/or polyester-polyol(s) of mol. wt. 500-18000, optionally containing organic fillers. In this system, components (A) and (B) have functionalities of 4-8 and 3-8 respectively and are used in a stoichiometric ratio such that the elastomer obtained shows an isocyanate index of 80-120 and the polyol component introduced with component (B2) provides 10-90 mol% of the urethane content. An Independent claim is also included for reinforced PU/U elastomers obtained by this process.
Patent ES-2211100-T3 (ES)
Inventor: ISMAIL LABEEB K
IPC: H04N5/445
Filed: 1999-06-01
Granted: 2004-07-01
Abstract: A system for recording television programs for subsequent viewing by a user includes a preference determination module which is responsive to attribute information associated with television programs viewed by the user. The preference determination module categorizes the attribute information in accordance with categorization parameters to generate recordation preference information, indicative of television program viewing references of the user. The system also includes a recordation module which is responsive to the recordation preference information, for causing recordation on a storage medium of subsequently transmitted television programs, having attribute information corresponding to the recordation preference information.
Patent ES-2222713-T3 (ES)
Title: Aparato para descomprimir hernias de discos intervertebrales.
Inventor: HOOGLAND THOMAS
IPC: A61B17/16
Filed: 1999-06-16
Granted: 2005-02-01
Abstract: Aparato para tratar una hernia de disco, comprendiendo el aparato una herramienta endoscópica (64) para la extracción de tejido blando y una cánula (40) de trabajo a través de la cual se puede hacer avanzar a dicha herramienta, estando caracterizado el aparato por: un conjunto (54, 56) de herramientas para extraer hueso de un par complementario de apófisis articulares superior e inferior de la columna vertebral, para crear una vía para el acceso endoscópico posterolateral hacia el foramen vertebral y el canal vertebral; y en el cual el conjunto de herramientas de extracción de hueso comprende un conjunto de barras (54) de trócar cuyo diámetro exterior que aumenta progresivamente, y un conjunto correspondiente de herramientas (56) de broca hueca en diente de sierra, cada una de las cuales encaja de forma ajustada sobre el diámetro exterior de su tubo correspondiente de trócar y es giratoria sobre el tubo para perforar a través del material óseo de alrededor de la articulación facetaria de la columna vertebral correspondiente al disco vertebral herniado en tratamiento.
Patent ES-2230899-T3 (ES)
Title: Antagonistas iii receptores de 4-aroil-piperidin-ccr-3.
Inventor: GONG LEYI
IPC: C07D405/12
Filed: 1999-11-08
Granted: 2005-05-01
Abstract: Un compuesto seleccionado entre los compuestos de **fórmula** en donde: Ar1 y Ar2 son, independientemente entre sí, arilo o heteroarilo; R y R1 son hidrógeno; R2 es un grupo alquilo ramificado de 3 o 4 átomos de carbono; X es un grupo seleccionado de: (a) -C(O)N(R3)-; (b) -NHC(O)N(R3)-; en donde: R3 y R4 son hidrógeno, alquilo o heteroaralquilo e Y es un enlace o alquileno con 1-3 átomos de carbono; y sus ésteres, carbamatos, isómeros individuales, mezclas de isómeros, y sales farmacéuticamente aceptables de los mismos.
Patent ES-2190668-T3 (ES)
Title: Dispositivo y procedimiento de encuadernacion.
Inventor: REBORA FRANCESCO
IPC: B42B5/10
Filed: 1999-10-25
Granted: 2003-08-01
Abstract: Dispositivo para encuadernar hojas dispuestas en un paquete usando un elemento de encuadernación (8, 8a) incluyendo al menos un elemento de hoja (100, 140) que tiene a lo largo de un lado (100a, 141) del mismo una pluralidad de lengüetas flexibles (107, 142) dispuestas a modo de peine; dicho elemento de encuadernación (8, 8a) tiene al menos una superficie de aplicación (113, 146), caracterizándose dicho dispositivo por incluir - un medio de alojamiento (33) para un paquete de hojas que tiene agujeros pasantes (133) dispuestos alineados a lo largo de una dirección sustancialmente rectilínea; estando adaptado dicho medio de alojamiento para disponer dicho paquete de hojas en una posición preestablecida para poder introducir dichas lengüetas dentro de dichos agujeros; - un medio de doblado (6) incluyendo un elemento de doblado (70) móvil con respecto a dicho medio de alojamiento (33), para doblar dichas porciones de lengüeta que sobresalen de dicho paquete sobre un elemento de extremo plano que forma una cara del mismo paquete, doblando además dicho medio de doblado (6) una porción de dicho elemento de encuadernación para disponer dicha superficie de aplicación (113, 146) solapando dichas lengüetas dobladas (107) y conectada establemente con dicho elemento de extremo plano (130a) formando un fascículo encuadernado.
Patent ES-2239471-T3 (ES)
Inventor: RADICE MARCO
IPC: C12N5/08
Filed: 1999-12-21
Granted: 2005-09-16
Abstract: Disclosed is an injectable, biocompatible and biodegradable composition, comprising at least one hyaluronic acid benzyl ester or auto-cross-linked derivative, in combination with at least one mammalian cell and/or at least one pharmacologically or biologically active substance and/or micro-particles such as fibres, granules, microspheres or sponge fragments of a hyaluronic acid derivative.
Patent ES-2310055-T3 (ES)
Inventor: REINHARD CHRISTOPH
IPC: C12N15/09
Filed: 1999-12-16
Granted: 2008-12-16
Abstract: A human gene encoding a novel cyclin-dependent kinase termed  hPNQALRE  and its expression products can be used to provide reagents and methods for detecting neoplasia. Compositions and methods for treating proliferative disorders and neoplasia are also provided.
Patent ES-2253930-T3 (ES)
Inventor: CALDERWOOD DAVID
IPC: A61P27/00
Filed: 1999-09-17
Granted: 2006-06-01
Abstract: Chemical compounds having structural formula (I) and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the kinases whose activity is inhibited by these compounds are involved in immunologic, hyperproliferative or angiogenic processes. Thus, these compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferative is a factor. These compounds can be used to treat cancer, hyperproliferation disorders, rheumatoid arthritis, disorders of the immune system, transplant rejection, and inflammatory disorders.
Patent PL-1550740-T3 (PL)
Title: Multiple step conversion coating process
Inventor: SCHENZLE BERND
IPC: C23C22/73
Filed: 2004-12-07
Abstract: A process for the chemical pretreatment, before an organic coating, of composite metal structures that contain aluminum or aluminum alloy portions together with zinc or zinc alloy portions, and steel, galvanized steel and/or alloy-galvanized steel portions, such that the phosphate level and the operating temperature of the zinc phosphate solution is reduced, and the nitrite accelerator level of the solution is increased. The process of the present invention reduces the sludge produced by the process, the temperature at which the process operates, and the need for monitoring the process. Furthermore, the pretreatment process of the present invention forms a conversion layer on all exposed metal surfaces that is suitable as a corrosion-preventing paint substrate, especially before a cathodic electro-dipcoating.
Patent PL-1626985-T3 (PL)
Title: Generation of artificial binding proteins based on ubiquitin proteins
Inventor: FIEDLER MARKUS
IPC: G01N33/68
Filed: 2004-05-27
Abstract: Proteins (A) of the ubiquitin-like protein superfamily that include at least one amino acid (aa) modification, at least in the surface-exposed region of the protein, so as to impart a binding specificity, for a predetermined binding partner, that is not present in the original protein are new. Proteins (A) of the ubiquitin-like protein superfamily that include at least one amino acid (aa) modification, at least in the surface-exposed region of the protein, so as to impart a binding specificity, for a predetermined binding partner, that is not present in the original protein are new. (A), or derived fragments or fusion proteins, retain the ubiquitin-like folding motif of the original protein, and the surface-exposed region includes at least one beta -fold region, optionally also a non-beta -fold region. An independent claim is also included for a method for preparing (A). ACTIVITY : Cytostatic. No biological data given. MECHANISM OF ACTION : Receptor or ligand blockade; targeted delivery of other effectors.
Patent PL-1644403-T3 (PL)
Title: Cytotoxic depsipeptides
Inventor: ROMERO PACO
IPC: C12P21/04
Filed: 2004-06-23
Abstract: Compounds of general formula (I) wherein R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3 </SUB>are as defined and R<SUB>4 </SUB>groups are each independently selected from NR<SUB>2</SUB>, O and S; are of use in treatment of cancers.
Patent PL-1589276-T3 (PL)
Title: Device for the construction of bases
Inventor: JACKSON COLOMER INES
IPC: E04B5/02
Filed: 2005-04-19
Abstract: "Device for the construction of bases"  of the type composed of two elements, concrete slabs (1) and slab union elements formed by two plates, one lower (2) and another upper (3), characterised essentially because the lower plate (2) has at least two perforations both with threads suitable to receive a bolt or stud for their fixing to the upper plate (3), which is formed by two parts united by a dovetail joint, each with a perforation to match those of the lower plate (2).
Patent PL-1722908-T3 (PL)
Title: Method for producing a composite part
Inventor: PINARD FABRICE
IPC: B32B38/12
Filed: 2005-02-17
Abstract: The procedure consists of coating at least one surface of a steel sheet less than 0 .65 mm thick with one or more adhesive polymer films with a total thickness of at least 0 .1 mm to form a composite laminated material . The polymer film can be extruded directly onto the sheet steel or made separately and applied to it by hot lamination or adhesive . The composite sheet material can be cut out to make a blank and shaped between a die and matrix of a stamping tool to make a component , the die being applied directly to the plastic -covered surface of the blank . Alternatively , the sheet material can be shaped by hydroforming or profiling .
Patent PL-1743229-T3 (PL)
Title: Certificate validity checking
Inventor: DURAND ALAIN
IPC: G06F21/00
Filed: 2005-04-22
Abstract: A method for checking a validity of a certificate (600) associated to a network device (621) in a network, comprises receiving at the network an encrypted content (611) and a validity index (630) associated to the content. The validity of the certificate is evaluated from a time index (606) contained within the certificate, the time index having a value corresponding to a time of issue of the certificate, and from the validity index associated to the encrypted content. <IMAGE>
Patent PL-2062484-T3 (PL)
Title: Process of manufacturing smokeless tobacco articles and smokeless tobacco article for oral consumption
Inventor: PIENEMANN THOMAS
IPC: A24B13/00
Filed: 2007-11-23
Abstract: In a process of manufacturing smokeless tobacco articles on a rod-making device, an endless tobacco web (1a), the filler web, is shaped into an endless rod (1b), preferably by use of a funnel-like formatting device (4). Another endless web (5a), the wrapper web, is provided as a wrapper and wrapped around the endless rod (1b). The endless wrapped rod is cut into individual cylindrical portions (11).
Patent PL-1971479-T3 (PL)
Title: Device for post-treating tyres
Inventor: MILITZER JEANNETTE
IPC: B29D30/06
Filed: 2007-01-09
Abstract: The invention relates to a device comprising a receiving device (3) for post-treating tires (1). After vulcanizing the elastomer material, the tires (1) are subjected to internal pressure by means of support gas, and cooled. Said receiving device (3) is embodied such that it can maintain the tires (1) and also seal the inner chamber of the tires. Also, a pressurized gas supply is connected to the receiving device (3). Said receiving device (3) comprises at least two fixed receiving areas (4) for at least two tires (1). The tires undergo at least one introduction process using a positionable handling device (19).
Patent PL-2050308-T3 (PL)
Title: Middle ear direct action improved hearing aid and related installation method
Inventor: PIZZOLI LAMBERTO
IPC: H04R25/00
Filed: 2007-07-26
Abstract: A middle ear prosthesis device and corresponding implantation procedure are described. A sensing microphone converts an acoustic audio signal into a corresponding electrical audio signal. A sensing amplifier amplifies the electrical audio signal. An audio transducer converts the amplified electrical audio signal into a corresponding amplified acoustic audio signal. An acoustic waveguide conducts the amplified acoustic audio signal from the audio transducer to the middle ear and includes: i. a main tubular portion having an outer end for placement in the outer ear canal and an inner end for placement in the middle ear, and ii. an extension portion having an outer end coupleable to the audio transducer and an inner end coupleable to the outer end of the main tubular portion.
Patent PL-2053155-T3 (PL)
Title: Laundry washing machine or washer-dryer comprising means for diverting the water flow
Inventor: PONT HERVé
IPC: D06F39/08
Filed: 2008-10-24
Abstract: The machine (4) has a body (3) enclosing a washing tank (1), and a stream waterway supplying valve (7) connected to a water circulation conduit (8) and a water circulation deviation unit (9) e.g. Y-shaped water flow separator. The deviation unit is connected to a water supplying conduit (10) to supply water discharging on a water utilizing device e.g. heating element (13), that generates vapor. The deviation unit is connected to a water-cooled condenser (6) e.g. condensation ramp, by a water supplying conduit (14) and a water supplying valve (15) that is in series with the valve (7).
Patent PL-2118908-T3 (PL)
Title: Device for broadcasting audio and video data
Inventor: NOGIER JEAN-MARC
IPC: H04N7/10
Filed: 2008-03-11
Abstract: The invention relates to a device for delivering audio and video data. In such a device, the audio/video data travel together and are compressed along with the signaling data for the delivery of these audio/video data. Under current compression standards, these data are being increasingly compressed. This maximum compression proportionally complexifies the encoding and decoding of audio/video data. The appearance of network cables comprising six twisted pairs of wires makes it possible to produce networks having higher speed capacities. The object of the invention is not to increase speeds by using additional twisted pairs but to simplify the data traveling through the network.
Patent PL-2170346-T3 (PL)
Title: Treatment or prevention of hypertensive disorders of pregnancy or fetal growth retardation
Inventor: VISSER MONIQUE
IPC: A61K31/565
Filed: 2008-07-14
Abstract: The present invention relates to the use of a steroid in the manufacture of a pharmaceutical composition for use in the therapeutic or prophylactic treatment of a hypertensive disorder of pregnancy (HDP) or fetal growth retardation, said treatment comprising administering to a female mammal a steroid selected from the group consisting of: substances represented by the following formula (formula I) in which formula R1, R2, R3, R4 independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R5, R6, R7 is a hydroxyl group; no more than 3 of R1, R2, R3, R4 are hydrogen atoms; precursors of such substances; and mixtures of one or more of the aforementioned substances and/or precursors.
Patent PL-2111517-T3 (PL)
Title: Illumination means
Inventor: EMDE THOMAS
IPC: F21Y101/00
Filed: 2008-12-11
Abstract: The present invention relates to illumination means (10) based on organic light diodes (OLED), having a layer arrangement (15) with at least one organic light-emitting diode layer (OLED layer), and at least one anode layer and one cathode layer on a carrier, and contact means (22) for the electrical contact of the electrode layers. According to the invention, the OLED layer and at least one electrode layer are attached to the inner side of a dimensionally stable rotation surgace serving as the carrier. According to the invention, the inner surface of a substantially or entirely closed hollow body (11) made of glass, plastic, or another light-transmissice material can serve as a carrier. The invention creates a novel illumination means (10) based on organic light diodes, having a shape that is compatible with a conventional light bulb or fluorescent lamp, and consequently can be exchanged for the same.
Patent PL-2366399-T3 (PL)
Title: Non-cytotoxic protein conjugates
Inventor: FOSTER KEITH
IPC: C12N9/64
Filed: 2005-12-01
Abstract: A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described.
Patent PL-3530673-T3 (PL)
Title: Humanized anti-beta7 antagonists and uses therefor
Inventor: DENNIS MARK S
IPC: C07K16/18
Filed: 2005-09-02
Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies
Patent GR-3006373-T3 (GR)
IPC: F23N5/24
Filed: 1992-11-27
Abstract: The present invention relates to a method for controlling the heating water circulation in a gas-fired water heater, consisting of at least one heat exchanger (2, 3) which is heated by a burner (1) and to which a heating water forward run pipe (8) with a temperature sensor (9) for forward run temperature regulation and a heating water return run pipe (7), in which there is a heating water circulating pump (6), are connected, the forward run temperature T2 being constantly controlled, and compared with a maximum forward run temperature Tmax stored in a regulating device (15) which is line-connected to an automatic firing machine (14) and the burner (1) being switched off in the event that this temperature is exceeded. In order to guarantee reliable switching off in the event of low water, it is envisaged according to the invention that the heating water temperature is measured at an additional point approximately in the centre between forward and return run pipe (7, 8) and the temperature difference  DELTA  T between the forward run temperature T2 and this heating water temperature T1 is determined. This temperature difference  DELTA  T is compared with a maximum temperature difference  DELTA Tmax and a minimum temperature difference  DELTA  Tmin stored in the regulating device (15) and this temperature difference  DELTA  T is used as second switch-off criterion  DELTA  T <  DELTA  Tmin, in addition to the first switch-off criterion T2 - T1 >  DELTA  Tmax. <IMAGE>
Patent GR-3008223-T3 (GR)
IPC: C01B13/02
Filed: 1993-06-18
Abstract: Condensation of feed gas constituents within a membrane system are efficiently and effectively precluded by positining the membrane system within an insulated enclosure heated to maintain superheat conditions for the feed gas passing to said membrane system. The membrane modules within the system are not individually insulated. A constant, stable temperature environment can readily be maintained within the enclosure, and advantageous flexibility can be achieved in the controlling of the operating temperature for process optimization purposes. The energy requirements of the overall operation are reduced by the advantageous recovery of feed gas compression heat for use in supplying heat to the feed gas within said insulated enclosure.