baber/WOPTO huggingface dataset:
Patent WO-2022261559-A3 (WO)
Inventor: Linstadt Roscoe
IPC: C09D5/16
Filed: 2022-06-13
Abstract: The present application discloses charged antifouling, coatings, and silicone polymers, and their methods of preparation, and methods of use.
Patent WO-2023064353-A3 (WO)
Title: Dispositif d'application d'agrafes asymétrique et cartouche
Inventor: BOYERS JESSICA
IPC: A61B17/122
Filed: 2022-10-12
Abstract: Dispositif d'application d'agrafes pouvant comprendre : un premier élément de mâchoire pour venir en prise avec un premier élément de patte d'un agrafeur chirurgical; et un second élément de mâchoire pour venir en prise avec un second élément de patte d'agrafeur chirurgical. Au moins l'un du premier élément de mâchoire et du second élément de mâchoire est asymétrique autour d'un plan médian du dispositif d'application d'agrafes. Une cartouche d'agrafes peut comprendre : une base ayant un premier axe et un second axe, le second axe étant perpendiculaire au premier; et une pluralité de parois définissant au moins une cavité destinée à recevoir l'agrafe chirurgicale. Au moins l'une de la pluralité de parois a une première partie de paroi sur un premier côté du premier axe et une seconde partie de paroi sur un second côté du premier axe. La première partie de paroi et la seconde partie de paroi sont décalées l'une par rapport à l'autre par rapport au second axe.
Patent WO-2023122195-A3 (WO)
Title: Méthodes anti-inflammatoires faisant intervenir des compositions comprenant des acides gras modifiés isotopiquement, spécifiques à un site
Inventor: SHCHEPINOV MIKHAIL
IPC: A61K31/202
Filed: 2022-12-21
Abstract: Sont divulguées ici des méthodes de traitement ou d'inhibition de la progression de maladies inflammatoires, consistant à administrer une quantité efficace d'une substance polyinsaturée à un patient atteint d'une inflammation et qui a besoin d'un traitement, la substance polyinsaturée étant modifiée chimiquement de sorte qu'une ou plusieurs liaisons sont stabilisées contre l'oxydation. La présente divulgation concerne plus particulièrement des méthodes de traitement, de réduction ou de prévention d'affections inflammatoires par l'administration à un sujet de compositions comprenant des acides gras polyinsaturés (PUFA) essentiels et des dérivés de ceux-ci comportant des modifications isotopiques spécifiques à un site au niveau d'une ou plusieurs positions « bis-allyliques » (un groupe CH2 situé entre deux fragments alcène) et/ou d'une ou plusieurs positions « pro-bis-allyliques » (un groupe méthylène qui devient une position bis-allylique après une désaturation).
Patent WO-2023087019-A3 (WO)
Title: Compositions for drg-specific reduction of transgene expression
Inventor: HORDEAUX JULIETTE
IPC: A61P25/00
Filed: 2022-11-15
Abstract: Methods of treating a genetic disorder and assessing AAV-induced dorsal root ganglia (DRG) toxicity in a subject are provided.
Patent WO-2023150693-A3 (WO)
Inventor: GHOSH SOUMITRA
IPC: C07K14/475
Filed: 2023-02-03
Abstract: Compositions of polypeptides are provided, which are analogs of neuregulin-4 and exhibit one or more activities of neuregulin-4, including the ability to induce homodimerization of ErbB4 subunits, the specificity in inducing homodimerization of ErbB4 over heterodimerization of ErbB family subunits. Various polypeptides described herein possess stability against enzymatic degradation. Methods of treating or reducing the likelihood of inflammatory bowel diseases are also provided using polypeptides that are analogs of human neuregulin-4.
Patent AT-519020-A4 (AT)
Title: Verfahren zur Herstellung von Biokohle und Anlage hierfür
Inventor: LEO SCHIRNHOFER
IPC: C10B53/02
Filed: 2016-09-26
Abstract: Verfahren und Anlage zur Herstellung von Biokohle, bei welchem in Retorten (1) befindliches biogenes Ausgangsmaterial (2) pyrolysiert wird und die durch die Pyrolysen entstehenden brennbaren Pyrolysegase zur Erzeugung von heißen Rauchgasen verbrannt werden, wobei die Retorten (1) zeitlich aufeinanderfolgend in mindestens eine Reaktorkammer (31, 31a, 31b, 31c) eingebracht werden und mittels der Rauchgase in diesen die Pyrolysen durchgeführt werden. Dabei sind die Retorten (1) gegenüber dem Eintritt von heißen Rauchgasen zumindest weitgehend abgeschlossen und erfolgt die Erhitzung der in den Retorten (1) befindlichen Ausgangsmaterialien (2) mittels der Rauchgase durch die Beheizung der Retorten (1) nur mittelbar.
Patent AT-502039-A4 (AT)
Filed: 2005-07-04
Abstract: The device has a granulating head (2) to which a perforated plate (3), provided with melt-discharge openings, is attached. The openings are swept by rotating knives (4) arranged in a knife holding device in a rotatable manner. The holding device is rotated by a drive shaft (18) of a motor via a magnetic clutch (15) in a contactless manner. A housing outlet (8) is arranged opposite to the head and allows a medium to be discharged through it along with granules. The clutch has coupling components (13, 14) arranged at a distance from each other and connected to the shaft and the holding device.
Patent EP-1179990-A4 (EP)
Inventor: HU GUIZHOU
IPC: G06F19/00
Filed: 2000-03-24
Abstract: L'invention concerne une technique et un dispositif (300) permettant d'évaluer le stade de la maladie d'un patient à l'aide de plusieurs facteurs de prédiction de maladies pour ce patient, et par l'application aux données d'une équation multidimensionnelle de prédiction de maladies en vue d'évaluer le stade de la maladie du patient. Le dispositif (300) comprend un processeur (301) ainsi qu'une mémoire (302) reliée au processeur (301). La mémoire (302) et le processeur (301) peuvent également être reliés à une base de données (304) en vue de stocker des données portant sur plusieurs facteurs de prédiction de maladies pour un patient, et à un port (303) permettant de rentrer des données dans un élément de transfert d'entrée (305) ou d'en sortir à partir d'un élément de transfert de sortie (305).
Patent EP-1190231-A4 (EP)
Title: System for electrochemical quantitative analysis of analytes within a solid phase
Inventor: LU FANG
IPC: G01N33/558
Filed: 2000-05-05
Abstract: System, method, and test strip for solid phase, electrochemical, quantitative analysis of analytes contained in biological fluid samples. Preliminary to analysis, a test sample solution can be applied to a sample collection pad associated with the solid phase test environment of the test strip. The test sample solution and a test kit reagent are thereby initially contacted, under assay conditions, within this solid phase test environment, and caused to migrate along a fluid pathway therein. Irrespective of the assay format (competitive assay, sandwich assay, etc.), a test kit reagent (e.g. labeled substance) and the analyte of interest (e.g. proteins, hormones or enzymes, small molecules, polysaccharides, antibodies, nucleic acids, drugs, toxins, viruses or virus particles, portions of a cell wall and other compounds which have specific or characteristic markers that permit their identification), either interact with one another to form a complex, or, alternatively, compete with one another for interaction with another test kit reagent, resulting in the concentration of an indicator substance within a delimited area of the solid phase. Thereafter, the delimited area of the test strip is subjected to electrochemical analysis and the results determined by monitoring an electrochemical transition in the form of an indicator, or derivative of the indicator (e.g. indicator species), by potentiostatic or potentiometric quantitative analysis (e.g. anodic stripping voltammetry). This electrochemical transition of the indicator has a characteristic electrical fingerprint that can be measured and which, when compared to a standard, can be correlated with the concentration of the analyte in the sample. This method is suitable for the determination/monitoring of therapeutic range of drugs (anti-convulsants drugs), determination of critical and potentially dangerous levels of endogenous materials which are indicative of disease states (prostate cancer), and numerous other applications presently requiring elaborate and time-consuming clinical laboratory analysis.
Patent EP-1106679-A4 (EP)
Title: Process for producing fermentation product
Inventor: SATO MASAHIDE
IPC: C12N11/10
Filed: 2000-06-30
Abstract: A process for producing a fermentation product by effecting fermentation with the use of a bioreactor having an immobilized microorganism located therein, characterized in that a non-flocculent yeast is employed as the microorganism. <IMAGE>
Patent EP-1130011-A4 (EP)
Title: Process for removing titanium oxide or iron oxide red from depolymerization products obtained by glycolysis of polyesters containing titanium oxide or iron oxide red with ethylene glycol
Inventor: INADA SHUJI
IPC: C07C67/48
Filed: 2000-09-05
Abstract: A process for efficiently removing titanium oxide or red oxide from an ethylene glycol solvolysis product of a polyester containing titanium oxide or red oxide. The process comprises the steps of:   (1) mixing at least one calcium compound selected from the group consisting of calcium oxide, calcium carbonate and calcium hydroxide with a polyester decomposition product containing titanium oxide which is an ethylene glycol solvolysis product of a polyester containing titanium oxide to agglomerate titanium oxide contained in the polyester decomposition product, or mixing titanium oxide with a polyester decomposition product containing red oxide which is an ethylene glycol solvolysis product of a polyester containing red oxide to agglomerate red oxide contained in the polyester decomposition product; and (2) subjecting the agglomerates to solid-liquid separation to remove titanium oxide or red oxide from the polyester decomposition product.
Patent EP-1240823-A4 (EP)
Title: N-calcium channel knockout animal
Inventor: INO MITSUHIRO
IPC: A61P9/12
Filed: 2000-10-26
Abstract: N-type calcium channel deficient non-human animals whose gene for the calcium channel has been disrupted, are new. N-type calcium channel deficient non-human animals whose gene for the calcium channel has been disrupted, are new. The gene that is disrupted has a defined sequence given in the specification (S1) or encodes the N-type calcium channel alpha 1B subunit and hybridizes under stringent conditions to sequence (S1). Independent claims are also included for the following: (1) a method for assaying usefulness of substances using the animal; (2) a method for screening for substances with potential pharmacological use; (3) useful substances found by the method; and (4) a method for producing pharmaceuticals using this method (specifically methods for producing a hypotensive drug, a pain killer and a drug for lowering blood sugar and the substances themselves). ACTIVITY : Hypotensive; Analgesic.
Patent EP-1257881-A4 (EP)
Inventor: KANGA RUSTOM SAM
IPC: G03F7/095
Filed: 2000-11-17
Abstract: La présente invention concerne un procédé de réalisation d'un cliché d'impression impressionné au laser. Pour commencer, on prend un cliché vierge non fixé et on le modifie au moyen d'un absorbeur d'ultraviolets et d'un absorbeur d'infrarouges. A cet effet, on préfère construire un feuillet de protection multicouche (12) comprenant au moins deux couches dont l'une (14) comprend un puissant absorbeur d'ultraviolets, l'autre (16) comprenant un absorbeur d'infrarouges à absorptivité élevée. Le feuillet de protection multicouche (12), qui est déjà conçu pour s'utiliser sur un cliché d'impression, s'applique selon les modalités habituelles sur la surface du cliché avant fixation. L'ablation du copolymère (18) du cliché revêtu du feuillet de protection multicouche (12) se fait au moyen d'un laser infrarouge fonctionnant à une longueur d'ondes choisie pour créer un négatif in-situ. Le négatif obtenu peut alors subir l'insolation aux ultraviolets et le développement.
Patent EP-1379537-A4 (EP)
Inventor: CLOYD MILES W
IPC: G01N33/566
Filed: 2001-04-19
Abstract: La présente invention concerne une méthode permettant de déterminer une infection latente par le VIH, consistant à détecter les séquence d'acides nucléiques du VIH de faible abondance dans des échantillons d'ADN cellulaire ou dans des parties de tissus fixées par la paraffine ou des parties congelées. Cette technique concerne également une amorce pour une séquence Alu dans l'ADN chromosomique humain et une autre amorce près de l'extrémité du LTR viral. On effectue alors l'hybridation de l'ADN amplifié par PCR au moyen d'une sonde ne reconnaissant que la séquence LRT amplifiée. Cette sonde peut être marquée de différentes façons, et des dosages quantitatifs d'infections latentes par le VIH ou par d'autres rétrovirus peuvent être développés.
Patent EP-1290224-A4 (EP)
Title: Diagnosis kit for mycobacterium species identification and drug-resistance detection and manufacturing method thereof
Inventor: KIM HYUN-JUNG
IPC: C12Q1/68
Filed: 2001-05-30
Abstract: The present invention relates to diagnosis kit for Mycobacterium species identification and drug-resistance detection and manufacturing method thereof, which can discriminate a Mycobacterium Tuberculosis rpoB gene point mutation relating to the Mycobacterium species identification and drug-resistance swiftly, exactly and in large quantities using an oligonucleotide chip. The diagnosis kit for Mycobacterium species identification and drug-resistance detection in accordance with the present invention consists of an oligonucleotide chip including a Mycobacterium tuberculosis complex probe, a Mycobacterium species identification probe and a drug-resistance detection probe of a Mycobacterium tuberculosis rpoB gene, and a fluorescent material containing a biotin-binding protein so as to detect hybridization of amplified products of a specimen marked as biotine and the corresponding probe.
Patent EP-1317809-A4 (EP)
Title: Method and system for steganographically embedding information bits in source signals
Inventor: RAMKUMAR MAHALINGAM
IPC: H04N1/387
Filed: 2001-08-02
Abstract: A method and system for embedding (E) information bits in a source signal (A) like images, audio or video. The embedding being performed optimally for a given worst-case scenario of unintentional or intentional attack of the host signal (to remove the embedded bits), and a given distortion of the host signal due to information embedding.
Patent EP-1385406-A4 (EP)
Title: Universal service bed
Inventor: KHAIT GEORGE
IPC: A61G7/02
Filed: 2001-08-15
Abstract: A service bed comprising a chassis, a guide mechanism movably supported by the chassis, and a mattress having an undulation formed by routing the mattress through the guide mechanism. The guide mechanism includes dispensing and collecting rollers for installing at least one first stratum between the mattress and the occupant of the service bed and for removing at least one second stratum installed between the mattress and the occupant.
Patent EP-1328654-A4 (EP)
Title: A practical, cost-effective synthesis of coq10
Inventor: LIPSHUTZ BRUCE H
IPC: C07C46/00
Filed: 2001-08-14
Abstract: The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention.
Patent EP-1347839-A4 (EP)
Title: Method of decorating a ceramic article
Inventor: SECREST PATRICIA C
IPC: B41M5/00
Filed: 2001-11-30
Abstract: The present invention provides a method of decorating a ceramic article including: providing an ink composition including a metallic soap, the ink composition being a viscous oil or waxy solid at about 25° C.; heating the ink composition to reduce its viscosity to less than about 40 centipoise; depositing micro-droplets of the heated ink composition upon the ceramic article; and firing the ceramic article in an oxidizing atmosphere. In the most preferred embodiment of the invention, the ink composition is substantially solvent-free.
Patent EP-1379936-A4 (EP)
Title: Content security layer providing long-term renewable security
Inventor: KOCHER PAUL C
IPC: H04N21/442
Filed: 2002-03-28
Abstract: In an exemplary embodiment, digital content is mastered as a combination of encrypted data and data processing operations that enable use in approved playback environments. Player devices having a processing environment compatible with the content's data processing operations are able to decrypt and play the content. Players can also provide content with basic functions, such as loading data from media, performing network communications, determining playback environment configuration, controlling decryption/playback, and/or performing cryptographic operations using the player's keys. These functions allow the content to implement and enforce its own security policies. If pirates compromise individual players or content titles, new content can be mastered with new security features that block the old attacks. A selective decryption capability can also be provided, enabling on-the-fly watermark insertion so that attacks can be traced back to a particular player. Features to enable migration from legacy formats are also provided.
Patent EP-1425112-A4 (EP)
Title: Nanogels and their production using liposomes as reactors
Inventor: KAZAKOV SERGEY
IPC: B01J13/02
Filed: 2002-08-15
Abstract: The present invention includes a method for preparing polymer hydrogel spherical particles on a nanometer scale (nanogels). The method includes encapsulating hydrogel-forming components into liposomes, diluting the large unilamellar liposomes suspension to prevent polymerization outside the liposomes, and polymerizing the encapsulated hydrogel-forming components. The lipid bilayer may be solubilized with detergent. The phospholipid and detergent molecules and their micelles may then be removed by dialysis. The resulting nanogels may then be dried by evaporation in a temperature gradient. Poly(acrylamide), poly(N-isopropylacrylamide), and poly(N-isopropylacrylamide-co-1-vinylimidazole) hydrogel particles with a diameter from 30 to 300 nm were detected and characterized by dynamic light scattering technique. The solvent, temperature, pH, and ionic sensitivities of the nanogels were studied.
Patent EP-1436399-A4 (EP)
Title: Animal integration vector and methods for its use
Inventor: FOGARTY PATRICK
IPC: C12N15/90
Filed: 2002-09-19
Abstract: Novel P element containing vectors and methods for their use to insert an exogenous nucleic acid into the genome of an animal are provided. The subject vectors have a pair of P element transposase recognized insertion sites, e.g. 31 base pair inverted repeats, flanking at least one transcriptionally active gene that is in proximity to at least one of the P element transposase recognized sites. In practicing the subject methods, a vector of the subject invention is introduced into the animal cell under conditions sufficient for transposition to occur. The subject methods find use in a variety of applications in which the insertion of an exogenous nucleic acid into the genome of an animal is desired, e.g. include research, synthesis and therapeutic applications.
Patent EP-1439162-A4 (EP)
Title: Process for producing optically active 3,5-dihydroxycarboxylic acid derivative
Inventor: SUGAWARA M
IPC: C07C67/31
Filed: 2002-10-24
Abstract: A method for producing an optically active 3,5-dihydroxyhexanoic acid derivative by stereoselectively reducing an optically active 3-oxo-5-hydroxyhexanoic acid derivative is provided. The method, which requires neither an ultralow-temperature reactor, an incubator, nor protection of the 5-position hydroxy group, is simple and economical. <??>An optically active 3,5-dihydroxyhexanoic acid derivative is produced by asymmetrical hydrogenation of an optically active 3-oxo-5-hydroxyhexanoic acid derivative catalyzed by an RuBr2BINAP complex prepared from a ruthenium complex and a ruthenium-optically active phosphine complex, i.e., 2,2'-bisdiarylphosphino-1,1'-binaphthyl (BINAP), while using extremely inexpensive hydrogen as the reductant.
Patent EP-1415004-A4 (EP)
Inventor: HASSIBI ARJANG
IPC: C12Q1/68
Filed: 2002-06-28
Abstract: L'invention concerne des procédés de quantification d'acides nucléiques au moyen d'un cycle régénérateur de bioluminescence (BRC). Dans le cycle BRC, des niveaux d'état stationnaire de bioluminescence résultent de processus qui produisent du pyrophosphate. Le pyrophosphate réagit avec de l'APS en présence d'ATP sulfurylase afin de produire de l'ATP. L'ATP réagit avec la luciférine, dans une réaction catalysée par la luciférase, produisant de la lumière et régénérant le pyrophosphate. Le pyrophosphate est recyclé afin de produire de l'ATP et le cycle régénérateur continue. En raison du fait que la cinétique de l'ATP sulfurylase est beaucoup plus rapide que celle de la luciférase, il en résulte un état stationnaire dans lequel les concentrations d'ATP et de pyrophosphate et le taux de production de lumière restent relativement constants. Les photons sont comptés pendant un intervalle de temps afin de déterminer le nombre de molécules cibles présentes dans l'échantillon initial. Le processus BRC comporte un domaine dynamique gérable jusqu'à sept ordres de grandeur et il est assez sensible pour détecter quelques milliers de molécules d'acides nucléiques cibles.
Patent EP-1554938-A4 (EP)
Title: Flavor deterioration inhibitor and inhibitor for the generation of citral deterioration smell
Inventor: ADACHI KENJI
IPC: A23L27/20
Filed: 2003-04-09
Abstract: A flavor deterioration inhibitor which comprises an extract obtained by extracting Angelica keiskei, avocado, Cassia tora, Plantago asiatica L, hawthorn, fermented tea leaves or semi-fermented tea leaves with water, an organic polar solvent or a mixture thereof; and a deterioration smell inhibitor for citral or a citral-containing product. By adding the above flavor deterioration inhibitor to foods, drinks or oral care products, it is possible to inhibit the deterioration of a flavor which is easily affected by light, heat, oxygen and so on. In particular, a remarkable inhibitory effect can be achieved on deterioration due to light. By blending the above deterioration smell inhibitor with ctiral or a citral-containing product, the generation of the deterioration smell (caused by p-cresol and p-methylacetophenone) due to the passage of time or heating can be effectively inhibited.
Patent EP-1552120-A4 (EP)
Inventor: GUI XINQUN
IPC: F01N3/08
Filed: 2003-06-30
Abstract: L'invention concerne un dispositif (30) de commande destiné à commander un mécanisme (26) d'actionnement à programme variable d'un moteur (10) à combustion interne afin de régénérer un catalyseur (35) adsorbeur de NOx dans le système (22) d'échappement du moteur. Le dispositif de commande comprend un programme (50) d'exploitation permettant de régénérer le catalyseur tandis que le moteur tourne grâce à sa propre énergie, en fonction duquel le mécanisme d'actionnement à programme variable change la programmation de fonctionnement des soupapes (18) d'admission de manière à convertir le rapport carburant-air du mélange en combustion dans les cylindres (16) d'un mélange relativement appauvri à un mélange suffisamment plus riche que l'état stoechiométrique pour régénérer de manière efficace le catalyseur.