baber/WOPTO huggingface dataset:
Patent EP-3591045-A1 (EP)
Inventor: PASCHON DAVID
IPC: C12N9/22
Filed: 2014-08-28
Abstract: Disclosed herein are compositions for linking DNA-binding domains and cleavage domains to form nucleases, for example nucleases with altered target site separation (gap) preferences as compared to conventional linkers. Also described are fusion proteins comprising these linkers. The disclosure also provides methods of using these fusion proteins and compositions thereof for targeted cleavage of cellular chromatin in a region of interest and/or homologous recombination at a predetermined region of interest in cells. Thus, in one aspect, described herein are amino acid sequences linking a DNA-binding domain to a cleavage domain. The linker may replace one or more residues of the DNA-binding domain and/or cleavage domain.
Patent EP-3626309-A1 (EP)
Inventor: TAVAZOIE SOHAIL
IPC: A61K31/416
Filed: 2013-08-13
Abstract: The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.
Patent EP-3647324-A1 (EP)
Inventor: KIM JEONG
IPC: A61P35/00
Filed: 2014-12-17
Abstract: The invention provides methods and compositions for treating cancer and for enhancing immune function in an individual having cancer. The methods comprise administering a PD-1 axis binding antagonist and a taxane.
Patent EP-3793077-A1 (EP)
Inventor: PAATERO ESA-KAI
IPC: H02J9/06
Filed: 2019-09-12
Abstract: The invention relates to a method for operating an uninterruptible power supply, UPS, (1, N) for connecting a load (2) to an AC source (3) and a DC source (4), the UPS (1, N) comprising a first converter assembly (5) comprising at least two first converters (6) connected on a first side to the AC source (3) and on a second side to a split DC link (7) comprising two halves with a midpoint reference (8), a second converter assembly (9) comprising a second converter (10) connected on a first side to the DC link (7) and on a second side to the load (2), a third converter assembly (11) comprising a third converter (12) connected on a first side to the DC source (4) and on second side to the DC link (7), a first controlled device (15) configured for disconnecting at least two of the first converters (6) from the AC source (3), and a second controlled device (16) configured for connecting at least two of the first converters (6) together, and comprising the step of: Opening the first controlled device (15), and closing the second controlled device (16) such that the first converter assembly (5) transfers energy between the split DC link halves (8) to maintain voltage regulation of the DC link (7) in respect to the midpoint reference (8).
Patent EP-3647717-A1 (EP)
Inventor: LIU WEIDONG
IPC: B23Q3/06
Filed: 2019-10-04
Abstract: A wheel space detecting device comprises a synchronous clamping mechanism position on a base, means for rotating the wheel hub and means for moving a measuring probe along a vertical axis and along an horizontal axis. The present invention can meet the needs of wheel brake space detection with a simple structure, stable detection performance, high positioning precision, simple operation and the like. It is therefore suitable for automatic batch production.
Patent EP-3636902-A1 (EP)
Inventor: FEDEWA ANDREW
IPC: F02D41/00
Filed: 2019-10-07
Abstract: A method (300) for controlling an internal combustion engine (12) having a plurality of cylinders (64a,64b,64c,64d) including a first cylinder (64a) and one or more remaining cylinders (64b,64c,64d) includes selecting (302) a desired auto-ignition dwell for a first combustion cycle for the first cylinder (64a) of the plurality of cylinders (64a,64b,64c,64d). A first fuel mass is provided (304) to the first cylinder (64a) which is combusted during the first combustion cycle. An actual auto-ignition dwell for the first combustion cycle which results from the first fuel mass is determined (306) and a dwell error is calculated (308). The dwell error is used to determine (312) a second fuel mass which provided to the first cylinder (64a) and which is combusted during the second combustion cycle.
Patent EP-3805458-A1 (EP)
Inventor: VAITKUS Audrius
IPC: E01C7/18
Filed: 2019-10-10
Abstract: The aim - by using asphalt pavement design model ViaStructura to design road pavement structure and technological process for its application. The model of pavement structural layers and partial layers shall take into account the total effect of the groups of vehicle axle loads and air temperature. Asphalt pavement structure, consisting of asphalt wearing layer, asphalt binder layer, asphalt base layer and unbound mineral material layers, is distinguished by the fact that thicknesses of the layers were optimized based on mechanical properties of materials and vehicle axle load of, for example, 7 million ESA, and pavement structure durability was checked by an individual-design model ViaStructura taking into account temperature and load spectra effects. The structure of asphalt pavement consists of: 
     Asphalt wearing layer (SMA 11 S) - 2,5-4,0 cm, 
Asphalt binder layer (AC 16 AS) - 4,0-8,0 cm, 
Asphalt base layer (AC 22 PS) - 7,0-15,0 cm, 
Crushed-stone base layer (SPS fr. 0/45) - 15,0-20,0 cm, 
Frost resistant layer (AŠAS) - 40,0-70,0 cm, 
Subgrade (ŽS) soils of average (F2) frost-susceptibility EV 2  ≥ 70 MPa.
Patent EP-3647549-A1 (EP)
Title: Gas turbine boas spring clip
Inventor: JOHNSON DEAN W
IPC: F01D11/08
Filed: 2019-10-31
Abstract: A clip (52) for an air seal assembly, comprising a clip base (54) having a control ring interface (55); a biasing element (56) coupled to the clip base opposite the control ring interface (55); wherein the clip (52) is insertable into a clip receiver (50) and configured to engage a notch (78) of a blade outer air seal (36) and configured to detachably couple with a clip mounting flange (58).
Patent EP-3819533-A1 (EP)
IPC: F21V29/70
Filed: 2019-11-06
Abstract: The invention refers to a carrier (2) for at least one lighting module (4), the carrier (2) comprising: at least one mounting portion (6) for receiving the at least one lighting module (4), wherein the carrier (2) has a triangular cross section at least in sections with the at least one mounting portion (6) being arranged on an edge of the triangular cross section; and a heat sink body portion (8) arranged adjacent to the at least one mounting portion (6), wherein the heat sink body portion (8) protrudes sidewards from the at least one mounting portion (6). The invention further relates to a lighting device (12) and a method for producing such lighting device (12).
Patent EP-3650552-A1 (EP)
Inventor: CHOU CHIA-FU
IPC: C12Q1/68
Filed: 2019-11-08
Abstract: A method for sizing a DNA molecule is disclosed, which comprises the following steps of: providing a DNA sizing device, comprising: a cover substrate; a substrate disposed on the cover substrate and comprising a first hole and a second hole; and a first slit-like channel disposed between the cover substrate and the substrate, wherein two ends of the first slit-like channel respectively connects to the first hole and the second hole; loading a sample comprising a DNA molecule to the first slit-like channel through the first hole, wherein the DNA molecule moves in a direction from the first hole to the second hole; detecting and recording an intensity and an area of a distribution of the DNA molecule; and analyzing the intensity and the area to obtain the size of a DNA molecule.
Patent EP-3822882-A1 (EP)
Inventor: RUDOLPH MAJA RITA
IPC: G06Q10/06
Filed: 2019-11-18
Abstract: The invention relates to a computer-implemented method (800) of estimating causal effects in a physical system, in which a measurable output quantity is affected over multiple points in time by at least one measurable treatment quantity. Latent dynamics of the physical system are captured by latent feature vectors of a temporal latent variable model. For a set of labelled observations, latent feature vectors at multiple points are determined based on the treatment quantity according to the temporal latent variable model. To estimate a causal effect of the treatment quantity on the output quantity, a regression model is fitted which estimates the output quantity from at least the measurements of the treatment quantity and the latent feature vectors at the multiple points in time.
Patent EP-3824777-A1 (EP)
Inventor: SCHMITZ KEVIN
IPC: A47J43/04
Filed: 2019-11-21
Abstract: Die Erfindung betrifft ein Verfahren für eine Zubereitung einer Speise mit einem Speisenzubereitungsapparat (101) und einer elektrisch betreibbaren Gewürzabgabevorrichtung (1), wobei der Speisenzubereitungsapparat (101) einen Speisenzubereitungsraum (102) aufweist und die Gewürzabgabevorrichtung (1) eine Gewürzkammer (6) für die Lagerung eines Gewürzes und eine Dosiereinrichtung (11, 12) umfasst, durch die ein Gewürz dosiert aus der Gewürzkammer (6) entnommen werden kann, mit den Schritten:• in dem Speisenzubereitungsraum (102) wird eine Speise gesteuert durch eine Steuereinheit gemäß Rezeptschritten eines Rezepts zubereitet,• das Rezept umfasst einen Gewürzrezeptschritt, gemäß dem ein Gewürz hinzugefügt werden soll,• wird der Gewürzrezeptschritt erreicht, so wird gesteuert durch die Steuereinheit ein Signal durch eine Signaleinrichtung (4, 110) ausgelöst;• im Anschluss an das Signal ergreift ein Benutzer die Gewürzabgabevorrichtung (1) und bringt die Gewürzabgabevorrichtung (1) so zum Speisenzubereitungsraum (102), dass ein Gewürz aus der Gewürzabgabevorrichtung (1) in den Speisenzubereitungsraum (102) abgegeben werden kann, oder so zu einem Messgefäß (107), dass das Gewürz aus der Gewürzabgabevorrichtung (1) in das Messgefäß (107) abgegeben werden kann;• ist die Gewürzabgabevorrichtung (1) durch den Benutzer zum Speisenzubereitungsraum (102) oder zum Messgefäß (107) gebracht worden, so gibt die Gewürzabgabevorrichtung (1) die Menge an Gewürz dosiert ab, die nach dem Gewürzrezeptschritt hinzugefügt werden soll, wobei die Dosierung durch die Dosiereinrichtung (11, 12) automatisiert erfolgt ist.Die Erfindung betrifft eine Gewürzabgabevorrichtung (1) zur Durchführung des Verfahrens.Auch ohne Fachwissen gelingt es durch die Erfindung, im Rahmen der Zubereitung einer Speise fehlerfrei zu würzen.
Patent EP-3828767-A1 (EP)
Inventor: KROENKE SVEN
IPC: G06K9/62
Filed: 2019-11-26
Abstract: The present invention relates to landmark and/or temporal event detection. It is proposed to utilize previously learned spatial correlations between multiple landmarks in order to regularize convolutional neural networks (CNNs) either as a post-processing step or during training in order to utilize anatomical prior knowledge, reduce the false-positive prediction rate, and/or increase the accuracy and stability of the algorithm. The proposed apparatus and method may also be applied to improve the detection of correlated events in e.g., time-series by leveraging prior knowledge.
Patent EP-3671786-A1 (EP)
Inventor: SCHMIDT PATRIK
IPC: H01H85/54
Filed: 2019-12-11
Abstract: Die Erfindung betrifft eine Anordnung eines Trägerteils (2). eines Oberteils (3) und eines Deckels einer Schalteinrichtung mit in der Anordnung integrierten Komponenten einer Elektronik. Bei der Schalteinrichtung kann es sich beispielsweise um einen Trennschalter oder eine Schaltleiste handeln.Das Oberteil (3) ist mit dem Trägerteil (2) mechanisch verbindbar, wobei in dem Trägerteil (2) eine erste Komponente der Elektronik gelagert ist, wobei in dem Oberteil (3) eine zweite Komponente der Elektronik gelagert ist, wobei die erste Komponente eine erste Verbindungseinrichtung aufweist, wobei die erste Verbindungseinrichtung in dem Trägerteil (2) gelagert ist, wobei die zweite Komponente eine zweite Verbindungseinrichtung aufweist, wobei die zweite Verbindungseinrichtung in dem Oberteil (3) gelagert ist, wobei die erste Verbindungseinrichtung und die zweite Verbindungseinrichtung miteinander elektrisch und/oder optisch koppelbar sind, zur Herstellung einer elektrischen und/oder optischen Verbindung zwischen der ersten Komponente und der zweiten Komponente durch elektrisches und/oder optisches Koppeln der ersten Verbindungseinrichtung mit der zweiten Verbindungseinrichtung beim mechanischen Verbinden von Trägerteil (2) und Oberteil (3).
Patent EP-3838547-A1 (EP)
Title: Verfahren zur herstellung einer haltevorrichtung
Inventor: STEINKELLNER JOHANN
IPC: B29C45/16
Filed: 2019-12-18
Abstract: 1. Verfahren zur Herstellung einer Haltevorrichtung (1), wobei in der Haltevorrichtung (1) ein Lichtführungskanal (2) ausgebildet ist, welcher sich von einem ersten Endabschnitt (2a) zu einem zweiten Endabschnitt (2b) der Haltevorrichtung (1) erstreckt, wobei der erste Endabschnitt (2a) einen Aufnahmebereich aufweist, in welchem ein erste optisches Element (3) formschließend befestigbar ist, wobei der zweite Endabschnitt (2b) eine Anschlagfläche (5) zur Verbindung mit einem zweiten optischen Element (4) aufweist, wobei das Verfahren die folgenden Schritte umfasst:a) Bereitstellen des ersten optischen Elements (3),b) Bereitstellen einer Spritzgussvorrichtung zur Durchführung eines Spritzgussverfahrens, wobei die Spritzgussvorrichtung zwei Werkzeughälften aufweist,c) Einbringen des ersten optischen Elements (3) in die erste Werkzeughälfte der Spritzgussvorrichtung,d) Schließen der Werkzeughälften,e) Ausbilden des ersten Endabschnittes (2a) der Haltevorrichtung,f) Ausbilden eines den Lichtführungskanal (2) umschließenden Mantels der Haltevorrichtung (1),g) Ausbilden des den Mantel der Haltevorrichtung (1) abschließenden zweiten Endabschnittes (2b) mitsamt der Anschlagfläche (5).
Patent EP-3700037-A1 (EP)
Inventor: SORENSON RICHARD W
IPC: H01H71/04
Filed: 2019-12-23
Abstract: A circuit breaker includes contacts movable between a closed position wherein a line terminal and a load terminal are in electrical communication, and an open position wherein the line and the load terminals are electrically isolated. A primary trip coil and a secondary trip coil are connected to the contacts, each causing the contacts to move from the closed position to the open position when activated, thereby tripping the breaker. A monitoring circuit, upon a determination being made that the breaker is not operating within acceptable trip parameters, causes activation of the primary trip coil, and, upon a determination being made that the breaker is not operating within acceptable disable parameters, causes activation of the secondary trip coil. The breaker is user resettable if the breaker has been tripped by the primary trip coil, but is not user resettable if the breaker has been tripped by the secondary trip coil.
Patent EP-3841935-A1 (EP)
Inventor: LOPEZ RUIZ JOSE MARIA
IPC: A47J31/44
Filed: 2019-12-27
Abstract: The system for foaming milk comprises a milk container (2); an air inlet (3); a pump (4), wherein the milk is mixed with the air in order to produce foamed milk; and an outlet (6), wherein foamed milk is supplied, and the system for foaming milk further comprises means (5, 8) for regulating the pressure at which the mixing of the milk and the air is performed.The method for foaming milk comprises the following steps: feeding milk; feeding air; mixing the milk with the air in order to produce foamed milk; and supplying foamed milk, and further comprising the step of regulating the pressure at which the mixing of the milk and the air is performed.It enables a system and method for foaming milk to be provided which does not require the milk to be heated, with the advantages that this entails.
Patent EP-3743627-A1 (EP)
Inventor: VARALE ALBERTO
IPC: F16L3/237
Filed: 2019-01-18
Abstract: A clamp (20) for mounting cables (29) to a tubular supporting element (30), said clamp (20) being composed of a jumper having a C-shaped cross-section with two opposing wings (21,22) interconnected by a core (23), wherein a movable thrust plate (38) is provided between said two opposing wings (21,22), and wherein said tubular supporting element (30) can be tightened between said thrust plate (38) and the wing (21,22) opposed to the same. At least one of said wings (21,22) opposing said thrust plate (38) is provided with a longitudinal groove (40) in which a portion of the casing of said tubular supporting element (30) can be engaged.
Patent EP-3737368-A1 (EP)
Inventor: SALM JACQUELINE I
IPC: A61K9/107
Filed: 2019-01-11
Abstract: Preparation of cannabinoid formulations containing: Δ9-tetrahydrocannabinol (Δ9-THC), Δ8-tetrahydrocannabinol (Δ8-THC), Δ9-tetrahydrocannabinolic acid (THCa), cannabidiol (CBD), cannabidiolic acid (CBDa), cannabigerol (CBG), cannabichromene (CBC) and cannabinol (CBN), either alone or in combinations henceforth known as cannabis, have been created using an emulsification process to encapsulate cannabinoids. The aqueous-based method involves micellular encapsulation of cannabinoids, a method that has been used to increase the bioavailability of poorly permeable, lipophilic drugs. These preparations demonstrates the viability of sublingual buccal, or oral delivery using an aqueous-based, encapsulation method, including as a beverage or drink.
Patent EP-3773230-A1 (EP)
Title: Ultrasound imaging system and method
Inventor: SCHADEWALDT NICOLE
IPC: A61B8/08
Filed: 2019-03-28
Abstract: A system for generating ultrasound data in respect of an anatomical body being scanned makes use of a predetermined scan protocol, which specifies a sequence of types of ultrasound scan of structures of interest. These types may for example be different imaging modalities (static, dynamic, 2D, 3D etc.) which are most appropriate for viewing different structures within the anatomical body. From received ultrasound images, a model is used to identify the structures of interest within the ultrasound images. The best images for creating the types of scan of the protocol are then identified and a sequence is compiled of those best images. In this way, a sequence is created which combines different types of scan, in a structured way according to a predetermined protocol. This makes the analysis of the sequence most intuitive for a user, and simplifies comparison between different sequences.
Patent EP-3942029-A1 (EP)
Inventor: MINCZUK MICHAL
IPC: C12N9/22
Filed: 2019-03-21
Abstract: L'invention concerne des procédés pour l'expression et l'administration simultanées à des mitochondries d'au moins deux protéines à l'aide d'un seul vecteur d'expression. L'invention concerne également les vecteurs d'expression et les cellules hôtes comprenant les vecteurs. Les protéines étant des réactifs d'édition de génome, l'invention concerne également l'utilisation des vecteurs d'expression pour modifier les niveaux d'hétéroplasmie mitochondriale et traiter des troubles mitochondriaux.
Patent EP-3937999-A1 (EP)
Inventor: STRASLY MARINA
IPC: A61L27/38
Filed: 2019-03-11
Abstract: Embodiments herein relate to a method of providing features (LCD, HD, HD_IN, HD_OUT) on an implantable material (ID), the method comprising: - providing an implantable material (ID) comprising a decellularized sterilized mammalian tissue having an extracellular matrix, wherein a plurality of interstitial spaces of the extracellular matrix include a solution of one or more polyols, - providing one or more features (LCD, HD, HD_IN, HD_OUT) on said implantable material (ID) by laser treatment.
Patent EP-3784842-A1 (EP)
Inventor: ROBERTS SAMUEL A
IPC: G05B19/418
Filed: 2019-04-08
Abstract: A method (600) for providing display redundancy on a machine (100) is provided. The machine (100) includes a first display (230) configured to perform a first set of functionalities (F1) associated with one or more operations of the machine (100) and a second display (232) configured to perform a second set of functionalities (F2) associated with the one or more operations of the machine (100), the second set of functionalities (F2) being different from the first set of functionalities (F1). The method (600) includes detecting (602), by a controller (202), failure of the first display (230). The method (600) further includes executing (604), by the controller (202), at least a subset of the first set of functionalities (F1) on the second display (232) along with at least a subset of the second set of functionalities (F2), when the failure of the first display (230) is detected.
Patent EP-3802363-A1 (EP)
Title: Pack for preparing food or beverage products
Inventor: MAGRI CARLO
IPC: B65D85/804
Filed: 2019-05-06
Abstract: The invention relates to a pack (100) for preparing a food or beverage product from one or more ingredients, the pack comprising an insert (10) through where the food or beverage product is delivered; the pack being configured by at least one flexible sheet folded in such a way to configure at least two distinct and separated volumes, an insert volume (300) where the insert (10) is enclosed, and a product volume (200) where one or more ingredients are stored; the at least one flexible sheet being arranged tightly over the frontal and rear parts of the insert (10) and matching these frontal and rear parts, such that there is a part of flexible sheet material configuring part of the pack (100) arranged below the insert (10). The invention further relates to the use of such a pack for preparing a food or beverage product and to a method for producing a food or beverage product using such a pack.
Patent EP-3775723-A1 (EP)
Inventor: SISHTLA VISHNU M
IPC: F04D27/02
Filed: 2019-04-08
Abstract: L'invention concerne un procédé de fonctionnement d'un système d'échangeur de chaleur dans lequel un compresseur, qui peut être entraîné par un moteur, est intercalé de manière fluidique entre un évaporateur et un condenseur après réception d'une commande d'arrêt. Le procédé comprend le positionnement d'aubes de guidage d'entrée (IGVs) du compresseur dans une première position dans le cas où au moins l'une d'une première condition préalable est en effet et la première et la seconde condition préalable n'étant pas en effet. Le procédé consiste en outre à positionner les IGVs dans une seconde position dans un cas où la première condition préalable n'est pas en effet mais la seconde condition préalable est en effet, à augmenter la vitesse du compresseur jusqu'à ce qu'une troisième condition préalable prenne effet, à retirer la puissance du moteur et à positionner les IGVs dans la première position une fois que la puissance est retirée du moteur.
Patent EP-3794515-A1 (EP)
Title: Concepts pour l'apprentissage distribué de réseaux neuronaux et/ou la transmission de mises à jour de paramétrage associées
Inventor: SAMEK WOJCIECH
IPC: G06N3/08
Filed: 2019-05-16
Abstract: La présente invention concerne plusieurs aspects d'amélioration de l'efficacité d'un apprentissage distribué.
Patent EP-3794280-A1 (EP)
Inventor: SEELEY ANDREW JAMES
IPC: F23D14/18
Filed: 2019-05-13
Abstract: A method for fabricating a component of an abatement apparatus is disclosed. The method comprises: meshing a 3D model representation of a component defining a reaction chamber of an abatement apparatus based on specified component characteristics to define an optimised finite element representation of the component; and fabricating the optimised finite element representation. In this way, a 3D model of a component of an abatement apparatus can be generated from which its performance can be modelled. Particular characteristics of the component may be defined which affect the operation of the abatement apparatus. Those characteristics may then be used to generate the optimized finite element representation of the component which has those characteristics using meshing (it will be appreciated that meshing is the operation of representing a geometric object as a set of finite elements). The optimized finite element representation may then fabricated, reliably producing a component having the required characteristics.