baber/WOPTO huggingface dataset:
Patent NZ-507222-A (NZ)
Title: Aminopiperidine derivatives useful as integrin antagonists
Inventor: MURAKAMI SHOICHI
IPC: C07D235/14
Filed: 1999-04-09
Abstract: An aminopiperidine derivative or a pharmaceutically acceptable salt or solvate thereof has the formula (I) wherein: A is an optionally saturated, optionally substituted 5 to 7 membered heterocyclic group containing two nitrogen atoms which is optionally condensed with another optionally saturated, optionally substituted 5 to 7 membered carbocyclic ring or heterocyclic ring to form a bicyclic group or A is R3N=C(R1)R2; R1 to R3 are independently hydrogen, nitrile or optionally substituted alkyl, alkenyl, alkynyl, or aralkyl or R1 and R2 may together form -(CH2)i- or - (CH2)2-O-(CH2)2-; D is >NR4,  >CR5R6, -O- or -S-; R4, R5 and R6 are independently hydrogen atom or optionally substituted alkyl; X and Z are independently CH or N; R7 is halogen, amino, nitro, hydroxyl, or oxygen or optionally substituted alkyl or alkoxy; R8 is halogen, amino, nitro, or hydroxyl or optionally substituted alkyl or alkoxy; Q is >C=O, >CHR13 or >CHOR13; R12 and R13 are independently hydrogen or alkyl; R9 is hydrogen or optionally substituted alkyl, alkenyl, alkynyl, or aralkyl; R10 and R11 are independently hydrogen or optionally substituted alkyl, alkenyl, alkynyl, aralkyl, or amino; m is 0 to 5; i is 4 or 5;  n is 0 to 4; p and q are independently 1 to 3; and r is 0 or 1. The above described compounds are useful for treating integrin avb3 -mediated diseases, cell adhesion inhibitory action diseases, GP IIb/IIIa antagonistic action and/or platelet agglutination inhibitory action such as cardiovascular diseases, diseases in association with neovascularization or cerebrovascular diseases.
Patent NZ-509267-A (NZ)
Title: A spray-dried bacteriocin powder with anti-microbial activity
Inventor: ROSS REYNOLDS PAUL
IPC: A23C9/123
Filed: 1999-06-22
Abstract: A process for producing a spray-dried lacticin 3147 powder, comprising: (a) inoculating a medium with a lacticin 3147 producing strain of bacteria, (b) fermenting the inoculated medium, (c) adjusting the pH of the fermentation to pH of 6.3-6.7, (d) inactivating the bacterial fermentate, (e) evaporating the fermentate of step (d) to form a concentrate, and (f) spray-drying the concentrate of step (e).
Patent NZ-510161-A (NZ)
Title: Axle filter for internally vented wheel assembly
Inventor: JONES RONALD LEE
IPC: B60B27/00
Filed: 1999-09-08
Abstract: A filter (10) is disposed in the interior cavity of each of the axle spindle (11) sections of a non-drive axle for a heavy duty tractor-trailer, which utilizes internally vented wheel end assemblies. Each filter (10) provides for sufficient air flow from the wheel end assembly cavity into the axle cavity to enable internal venting of any expanding gas from the wheel end assembly cavity into the axle cavity, thereby preventing excessive pressure build-up in the wheel end assembly and possible reduction of the life expectancy of the wheel end assembly main seal. Depending on the filter (10) embodiment employed, the filter prevents or at least lessens the likelihood of migration of contaminates such as oxide scale from the axle cavity into the wheel end assembly cavity, thereby causing premature wear of the wheel end assembly bearings or main seal.
Patent NZ-510529-A (NZ)
Title: Peptides that have thrombopoietic activity used to increase the production of platelets or platelet precursors
Inventor: LIU CHUAN-FA
IPC: C07K14/52
Filed: 1999-10-22
Abstract: Compounds of structure TMP1-(L1)n-TMP2 wherein TMP are structures of amino acids and L is a linker, said compounds bind to mpl receptors and thus have thrombopoietic activity by their ability to increase platelets or platelet precursors in a mammal.
Patent NZ-511838-A (NZ)
Title: Traction force sensing vacuum extractor
Inventor: WALLACE WILLIAM DEAN
IPC: A61B17/44
Filed: 1999-11-30
Abstract: A vacuum extractor (100) for use in childbirth is described. The vacuum extractor (100) includes a handle (110), and a vacuum cup (120) with a force sensor (130) coupled to the vacuum extractor (100). The force sensor (130) measures the traction force applied between the vacuum cup (120), and the handle (110) for assisting the birthing attendant in applying an appropriate traction force. The force sensor (130) may also include a slipping mechanism which causes the length of the force sensor (130) to distinctly increase if the applied traction force exceeds a certain level such as twenty pounds. Thus, the birthing attendant may feel the slipping, and thus determine that the traction force has exceeded the certain value.
Patent NZ-513718-A (NZ)
Title: Prefabricated housing, for external water heater, attachable to structure via fins in walls of housing
Inventor: GALJAARDT RICHARD ANTHONY
IPC: F24H9/02
Filed: 2001-08-22
Abstract: Prefabricated housing 10 has two side walls 12,13  and front  wall 14.  It  is insulated and is  attachable  to  a structure  via  fins 23 located in slotted  recesses  26  in walls 12,13.
Patent NZ-515569-A (NZ)
Title: Neurotrophic factor receptor GDNF family receptor alpha- 4 (GFRalpha-4)
Inventor: MASURE STEFAN LEO JOZEF
IPC: C12N15/113
Filed: 2000-05-26
Abstract: There  is  disclosed  a  mammalian  receptor  protein designated  GFRa-4  and the nucleic acid  sequence  encoding thereof.   Also provided is an expression vector  comprising the  nucleic  acid  sequence and host cells  transformed  or transfected   with   the  vector.    Isolated   host   cells expressing the receptor may be used to identify agonists  or antagonists in relation to the receptor.
Patent NZ-518238-A (NZ)
Title: Desulphurization sorbent compositions useful for removing sulphur from cracked gasoline or diesel fuel streams
Inventor: KHARE GYANESH P
IPC: C10G29/16
Filed: 2000-10-18
Abstract: A process for the production of a sorbent composition, suitable for the removal of sulphur from a cracked-gasoline or diesel fuel stream, comprises: (a) admixing of zinc oxide, silica, alumina and a calcium compound selected of calcium sulphate, calcium aluminate, calcium phosphate and calcium silicate; (b) particulating the resulting mix so as to form particles thereof; (c) drying the particulate of step (b); (d) calcining the dried particulate of step (c); (e) impregnating the resulting calcined particulate of step (d) with a metal, metal oxide or metal oxide precursor promotor; (f) drying the impregnated particulate of step (e); (g) calcining the dried particulate of step (f) and thereafter (h) reducing the resulting calcined particulate of step (g) with a suitable reducing agent under suitable conditions to produce a particulate composition having a substantially reduced valence promotor metal content therein such that the reduced valence promotor metal containing composition will effect the removal of sulphur from a stream of cracked- gasoline or diesel fuel when the stream is contacted with the reduced valence promotor metal containing composition under desulphurization conditions. The metal of step e) is cobalt, nickel, iron, manganese, copper, molybdenum, tungsten, silver, tin or vanadium or mixtures thereof.
Patent NZ-518267-A (NZ)
Title: Novel fucosylated oligosaccharides and process for their preparation
Inventor: NATUNEN JARI
IPC: A61P43/00
Filed: 2000-09-21
Abstract: Oligosaccharides of formula (I) are described, wherein the variables are defined herein. Also described are processes for producing the oligosaccharides.
Patent NZ-520951-A (NZ)
Title: 1,5-benzothiazepines and their use as hypolipidaemics
Inventor: STARKE INGEMAR
IPC: A61P3/06
Filed: 2001-03-05
Abstract: A compound of formula (I) that produces an ileal bile acid transport (IBAT) inhibitory effect and thus useful for the treatment of hyperlipidaemic conditions and related disorders is disclosed, wherein the variables are as defined in the specification. A process for the preparation of the compound of formula (I) is also disclosed.
Patent NZ-524393-A (NZ)
Title: Conveying frame for an endless conveyor
IPC: B65G21/00
Filed: 2003-02-25
Abstract: A frame (1) suitable for mounting an endless conveyor thereon, the frame being comprised of basic structural and fixing elements, such as screws and nuts wherein the basic structural element comprise five types: (a) a longitudinal structural element (10), (b) a stabilizer element (11), sildably fitting into at least two longitudinal structural elements placed behind each other, (c) a transverse structural element (12), (d) a pillar element (13) and (e) a mounting block (14), for mounting and mutually positioning the longitudinal structural elements (10), the transverse structural elements (12), and the pillar elements (13), wherein at least the longitudinal structural elements (10) and the transverse structural elements (12) are elongated cylindrical or prismatic material pieces, for instance hollow tubes or massive tubes, the cross section possessing a non-circularly symmetrical circumference, fitting with a close fit into corresponding recesses in said mounting blocks (14).
Patent NZ-529970-A (NZ)
Title: Method and apparatus for extermination of pests
Inventor: NEUSTROSKI JOHN RUSSELL
IPC: A01M23/34
Filed: 2003-12-04
Abstract: A pest extermination device includes a holder and a trigger mechanism. The holder is configured to hold an expanded resilient ring, and the device is configured to release the resilient ring free of the extermination device such that it contracts around a pest when a trigger mechanism is actuated by the pest, thereby exterminating the pest.
Patent NZ-531197-A (NZ)
Title: Indexable containers
Inventor: BLOMFIELD GREGORY THOMAS
IPC: B65D5/28
Filed: 2001-10-19
Abstract: A container formed from a blank of corrugated board where cuts between panels on a hinge axis (defined by hinging bridges (9) preferably adjacent an indexing projection (11)) reveal the flute ends (15 to 18) and thereby provide stack support for the base (1) of an indexing like container.
Patent NZ-532103-A (NZ)
Title: Alkylaminopyridazinone derivatives, process for their preparation and pharmaceutical compositions for the treatment of anxiolytic and cognitive disorders
Inventor: BARKOCZY JOZSEF
IPC: A61K31/50
Filed: 2002-09-26
Abstract: Substituted alkylaminopyridazinone derivatives of the general Formula (I) are described, wherein R1 is hydrogen or alkyl having 1-4 carbon atoms; one of X and Y stands for hydrogen or halogen and the other represents a group of the general Formula (II), R2 is hydrogen or alkyl having 1-4 carbon atoms; n is 1, 2 or 3; R3 stands for hydrogen, alkyl having 1-4 carbon atoms or aryl-(C1-4 alkyl); Z stands for oxygen; or R3 and Z together with the groups placed between them form a piperazine ring; and R4 stands for hydrogen, halogen, trifluoromethyl or alkoxy having 1-4 carbon atoms) and pharmaceutically acceptable acid addition salts thereof. These compounds are useful in the treatment of anxiolytic conditions and cognitive disorders in non human animals.
Patent NZ-534929-A (NZ)
Title: Macrocyclic peptides active against the hepatitis C virus
Inventor: LLINAS-BRUNET MONTSE
IPC: A61P31/14
Filed: 2003-01-24
Abstract: Compounds of general formula I or a pharmaceutically acceptable salt thereof, useful as inhibitors of the HCV NS3 protease.
Patent NZ-537653-A (NZ)
Title: Compounds useful for the treatment of cancer, compositions thereof and methods therewith
Inventor: MCKENNA JEFFREY
IPC: A61K31/351
Filed: 2003-06-17
Abstract: The use of a compound of formula (I): X, W and U are at each occurrence independently H, halogen, hydroxy, carboxy, alkoxy, alkylamino, branched or unbranched alkyl, alkenyl, alkynyl, haloalkyl, acyloxy, thioalkyl, sulfonyl, sulfinylalkyl, sulfonylalkyl, hydroxyalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocycle, substituted or unsubstituted cycloalkyl, -C(O)OR1, -OC(O)R1, -C(O)NR1R2, -C(O)NR1OR2, -SO2NR1R2, -NR1SO2R2, -CN, -NO2, -NR1R2, -NR1C(O)R2, -NR1C(O)(CH2)qOR2, -NR1C(O)(CH2)qR2, -NR1C(O)(CH2)qNR1R2, -O(CH2)qNR1R2; R1 and R2 are independently H or branched or unbranched alkyl; Y at each occurrence is independently H, branched or unbranched alkyl, or when o is 1, Y can be (=O) Z is C or O; Q is H, branched or unbranched alkyl; m is 0-5; n is 0-8; o is 0-2; p is 0-2; q.is 0-5; and r is 0-5; or a prodrug, clathrate, hydrate, solvate, polymorph, or pharmaceutically acceptable salt thereof, in the preparation of a composition for treating or preventing cancer or neoplastic disease.
Patent NZ-541738-A (NZ)
Title: Growth factor complexes and modulation of cell migration and growth
Inventor: UPTON ZEE
IPC: C12N5/071
Filed: 2004-02-05
Abstract: Disclosed herein are isolated protein complexes comprising growth factors such as IGF-I, IGF-II, VEGF or PDGF, or at least domains thereof that enable binding to and activation of both a growth factor receptor, and an integrin receptor-binding domain of vitronectin or fibronectin. These protein complexes may be in the form of oligo-protein complexes or single, synthetic proteins where the growth factor and vitronectin or fibronectin sequences are joined by a linker sequence. In particular forms, vitronectin or fibronectin sequences do not include a heparin binding domain and/or polyanionic domain. Also provided are uses of these protein complexes for stimulating or inducing cell migration and/or proliferation which may have use in wound healing, tissue engineering, cosmetic and therapeutic treatments such as skin replacement and skin replenishment and treatment of burns where epithelial cell migration is required. In other embodiments, the invention provides inhibition of cancer cell metastasis, particularly in relation to breast cancer.
Patent NZ-542090-A (NZ)
Title: Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
Inventor: KOSOGLOU TEDDY
IPC: C07D205/08
Filed: 2002-01-25
Abstract: Disclosed herein are compositions, therapeutic combinations and methods including: (a) at least one sterol absorption inhibitor; and (b) at least one blood modifier, which can be useful for treating vascular conditions and lowering plasma levels of sterols.
Patent NZ-542526-A (NZ)
Title: Lock assembly operable in latching or deadlocking modes
Inventor: CONSTANTINOU JOHN
Filed: 2005-09-21
Abstract: A lock assembly configurable for operation in either lock latching or deadlocking mode including a casing; a bolt mounted on the casing for linear movement relative thereto, the bolt having one end formed as a latch bolt and an opposing end formed as a deadbolt, the bolt being movable between a latch bolt extend position where the latch bolt extends out one side of the casing and a deadbolt extend position where the deadbolt extends out at an opposing side of the casing; a key operated actuator operable to move the bolt between the latch bolt extend position and the dead bolt extend position, a biasing means operable to bias the bolt towards the latch bolt extend position, a deadlock means operable to deadlock the bolt in the deadbolt extend position; and a selector for selecting the mode of operation of the lock assembly, the lock assembly being configured to operate in the lock latching mode when the selector is operable which renders the biasing means operable and a deadlock means inoperable, and the lock assembly being configured to operate in the deadlocking mode when the selector is inoperable which renders the biasing means inoperable and the deadlock means operable.
Patent NZ-542786-A (NZ)
Title: Yeast cream-dosing device and method using interchangeable transport container
Inventor: BLOMME KAREL ALFONS FRANS
IPC: B67D3/00
Filed: 2003-11-21
Abstract: Disclosed is a yeast cream-dosing device and method. The yeast cream is disposed in an interchangeable transport container ( 20 ) which is located inside a refrigerating compartment ( 10 ), the aforementioned container being connected to an extraction opening ( 27 ) by means of an outlet conduit ( 26 ) which can be opened and closed by an opening/closing mechanism ( 30 ).
Patent NZ-543274-A (NZ)
Title: Compositions for delivering peptide YY and PYY agonists
Inventor: DINH STEVE
IPC: A61K38/17
Filed: 2004-05-14
Abstract: A pharmaceutical composition comprising a delivery agent compound as shown in formula (I) and at least one of peptide YY (PYY) and a PYY agonist or a mixture thereof. The pharmaceutical composition facilitates the delivery of PYY, a PYY agonist, or a mixture thereof and increases its bioavailability compared to administration without the delivery agent compound. Also disclosed is the use of the pharmaceutical composition in the manufacture of a medicament for reducing nutrient uptake and reducing nutrient availability.
Patent NZ-548211-A (NZ)
Title: A power component magazine, power components, a power component assembly and methods of assembly
Inventor: HARRISON MICHAEL JOHN
Filed: 2006-06-28
Abstract: A power component magazine is disclosed. The power component magazine has a plurality of bays for receiving a plurality of components, and a connector for each bay for providing electrical connection between a component and power lines associated with the magazine. The connectors are movable relative to the magazine to enable connection with a component to provide a three-phase interface when in a first position and a single phase interface when in a second position.
Patent NZ-548327-A (NZ)
Title: Memantine for the treatment of mild and mild-to-moderate alzheimer's disease
Inventor: MCDONALD SCOTT
IPC: A61K45/06
Filed: 2005-01-05
Abstract: Disclosed is a use of memantine or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for treating mild to moderate alzheimer's disease, wherein the medicament is manufacture for administration of memantine at an initial dose of 5 mg/day rising weekly by 5 mg/day to a final dose of 20 mg/day.
Patent NZ-553297-A (NZ)
Title: CDC2 urine marker for detection of bladder cancer
Inventor: GUILFORD PARRY JOHN
IPC: C07H21/04
Filed: 2005-07-22
Abstract: Disclosed is a method for detecting bladder cancer in a subject, comprising: detecting the accumulation of a urinary bladder tumor marker ("UBTM") family member in the urine, said accumulation in said subject greater than about 1.2 times the accumulation of said UBTM in urine from a group of normal subjects not having malignant bladder cancer, charaterised in that the UBTM is cell division cycle 2, G1 to S and G2 to M (CDC2).
Patent NZ-553326-A (NZ)
Title: Use of liquid detergent containing fatty alkyl-1,3-diaminopropane for cleaning cleaning-in-place systems
Inventor: AHMED FAHIM U
IPC: C11D7/08
Filed: 2005-08-08
Abstract: Disclosed is a method of cleaning a clean-in-place (CIP) system comprising contacting the surfaces of said CIP system with a liquid detergent comprising an acid and a fatty alkyl-1,3-diaminopropane or salt thereof having the general formula R-NH-CH2CH2CH2NH2, where R is a C4-C22 alkyl group, said liquid detergent having a pH of between 0.1 to 5.
Patent NZ-555433-A (NZ)
Title: Process for evaluating fouling caused by refinery feedstocks
Inventor: BUTLER GRAHAM
IPC: C40B60/14
Filed: 2005-12-12
Abstract: A process for evaluating the fouling caused by a refinery feedstock on one or more refinery processes, is disclosed. The process comprises: (i) providing a plurality of refinery feedstocks and/or a plurality of fractions of one or more refinery feedstocks, (ii) providing an array comprising a plurality of metal samples representative of metallurgy present in a refinery, (iii) contacting each of the plurality of metal samples with one or more of the refinery feedstocks or fractions under non-static conditions in parallel, and (iv) determining the fouling caused by the refinery feedstock or fraction thereof, the determination for each metal sample being carried out in parallel.
Patent NZ-566103-A (NZ)
Title: Vehicle recovery and traction ladder
Inventor: MCCARTHY BRADLEY JOHN
IPC: B60B39/00
Filed: 2006-10-13
Abstract: A lightweight vehicle ladder for the recovery and traction of vehicles includes a central recessed portion (48) bordered by longitudinal strengthening ribs (56) and ramps (55) at either end. A plurality of traction members (52), each of which terminates in an upper tire engagement member (54) are disposed within the recessed portion and thereby somewhat protected from the ingress of mud during use in order that traction may be maintained. The underside and topside of the vehicle are formed with complementary shapes in order that a number of the ladders may be stacked one on top of the other to form a laminate of increased strength for application with particularly heavy vehicles.
Patent NZ-571121-A (NZ)
Title: Polycyclic cinnamide derivative
Inventor: KIMURA TEIJI
IPC: A61K31/4178
Filed: 2007-03-08
Abstract: Disclosed are polycyclic cinnamide derivatives represented by general formula (I), or pharmaceutical salts thereof, wherein Ar1 is an imidazolyl group and Ar2 is a phenyl or pyridyl group. Also disclosed is the compound of formula (I) for preventing a disease, such as Alzheimer's disease, dementia, Down's syndrome or amyloidosis, caused by amyloid-beta.
Patent NZ-571450-A (NZ)
Title: A glenoid plate for a reverse shoulder prosthesis
Inventor: ROCHE CHRISTOPHER P
IPC: A61F2/40
Filed: 2007-03-23
Abstract: A glenoid plate 110 for a reverse shoulder prosthesis 100, comprises a body portion 108 with a front and a back, and a stem portion 102 extending from the back of the body portion 108. The body portion 108 has a vertical dimension with a central point of the vertical dimension dividing the body portion 108 into an upper half and a lower half. The stem portion 102 has a central longitudinal axis. The stem portion 102 extends from the body portion 108 from a position on the body portion 108 such that the central longitudinal axis of the stem portion 102 is sufficiently superiorly shifted from the central point of the vertical dimension, so that when the glenoid plate 110 is implanted in a glenoid bone such that the stem portion 102 is positioned in a centre of the glenoid bone, a distal rim of the glenoid plate 110 will be aligned with a distal edge of an articular surface of the glenoid bone.
Patent NZ-572688-A (NZ)
Title: Heavy duty cable with an outer sheath having an extruded fibril reinforced polymeric matrix
Inventor: GALLETTI FRANCO
IPC: H01B7/18
Filed: 2006-05-22
Abstract: A heavy duty cable for applications which involve heavy mechanical stresses and/or harsh environmental conditions. The cable includes a core (2) having a transmissive element (3) and an outer sheath (5) disposed in a radially external position relative to the core (2). The sheath (5) includes at least one continuous reinforcing layer (6) consisting of an extruded compound made of a fibril reinforced polymeric matrix. The fibrils have an average length of from 0.1 to 2 mm. A process for manufacturing the cable is also disclosed.
Patent NZ-580588-A (NZ)
Title: Fused bicyclic heteroaryl derivatives
Inventor: SHIMADA KOUSEI
IPC: A61P1/04
Filed: 2008-04-02
Abstract: Disclosed are fused bicyclic heteroaryl derivatives represented by general formula (I), such as 3-{ [6-(3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy} benzoic acid, or pharmaceutically acceptable salts thereof. Also disclosed is the use of the compounds of general formula (I) for treating diabetes, activating PPAR-gamma, improving carbohydrate or lipid metabolism, improving insulin resistance, inhibiting inflammation, inhibiting the growth of cancer cells, for the treatment and/or prevention of hyperglycemia, hyperlipidemia, adiposity, impaired glucose tolerance, insulin resistance, impaired fasting glucose hypertension, fatty liver, non-alcoholic steatohepatitis, diabetic complications, arteriosclerosis, atherosclerosis, gestational diabetes mellitus or polycystic ovary syndrome.