baber/WOPTO huggingface dataset:
Patent IL-70558-A0 (IL)
Title: 1-(aminoalkoxyphenyl)-1-phenyl-propanols,their preparation and pharmaceutical compositions containing them
IPC: A61P25/30
Filed: 1983-12-27
Abstract: The invention relates to new aminopropanol derivatives of the formula (I)    <IMAGE>  (I)  wherein R1 is halogen, trihalomethyl, alkoxy having from one to 3 carbon atoms or alkyl having from one to 3 carbon atoms, R2 is alkyl having from one to 3 carbon atoms, and R3 is cycloalkyl having from 3 to 6 carbon atoms, or R2 and R3 together with the nitrogen they are attached to form an up to 8 membered ring optionally containing oxygen or a further nitrogen as an additional hetero atom, and optionally substituted with alkyl having from one to 4 carbon atoms or benzyl, and acid addition and quaternary ammonium salts thereof. According to another aspect of the invention there are provided processes for the preparation of these compounds. The new compounds are suitable for the treatment of acute ethanolic intoxication. Pharmaceutical compositions containing them are also within the scope of the invention.
Patent IL-81646-A0 (IL)
Title: Immunosorbent-amidolytic method for detecting human urinary plasminogen activator precursor(pro-upa)and human urinary plasminogen activator(u-pa)
IPC: C12Q1/58
Filed: 1987-02-23
Abstract: The present invention is directed to a method of selective assay of urinary plasminogen activator zymogen (pro-uPA) (commonly known also as pro-urokinase) and urinary plasminogen activator (u-PA) (commonly known also as urokinase) in biological fluids as well as in any kind of solution containing them, either separately or jointly. One feature of this method is in fact that it allows the determination of pro-uPA also in the presence of its enzymatically active derivative u-PA.
Patent IL-93594-A0 (IL)
Title: Pharmaceutical compositions containing an imidazopyrimidone derivative
IPC: A61P31/12
Filed: 1990-03-01
Abstract: Pharmaceutical use of a compound of formula (A): <CHEM> or a pro-drug, or a pharmaceutically acceptable salt, phosphate ester and/or acyl derivative of either of the foregoing; in the treatment of hepatitis B virus infections.
Patent FI-20020671-A0 (FI)
Inventor: KARINE SEPPO
IPC: B31B50/00
Filed: 2002-04-09
Abstract: A method and equipment for molding an article produced from paperboard or cardboard. Moulding is carried out by a molding tool that mechanically works the board; and to improve its moldability, momentary irradiation on the microwave frequency is exerted on the board. The method applies to the manufacture of packages and disposable containers made of paperboard or cardboard; for example, to the forming of a rolled-up or folded rim around a drinking cup, mug or a container, the forming of a stiffening crease or projection on a paperboard container, or to press molding of paperboard containers or plates.
Patent FI-20020997-A0 (FI)
IPC: B26D7/26
Filed: 2002-05-28
Abstract: A blade ( 10 ) for use in the slitting of a paper or board web has a hub part ( 11 ) and a blade part ( 15 ). The blade part ( 15 ) is releasably secured by means of securing members ( 12, 13 ) to the hub part ( 12 ). The securing members ( 12, 13 ) are formed so as to distribute and/or maintain the axial load enabling the joint to withstand high circumferential speeds.
Patent FI-20021432-A0 (FI)
Inventor: LEHTONEN KAI
IPC: F02M55/02
Filed: 2002-08-02
Abstract: Fuel supply system comprising at least a fuel source and a high-pressure pump in flow communication therewith for raising the fuel pressure up to an increased pressure, at least two fuel injectors arranged in conjunction with engine cylinders, each of which injectors is in flow communication with the high-pressure pump, and via a pressure accumulator unit. At least one pressure accumulator unit is in connection with both the fuel injector and at least one other pressure accumulator unit for fuel.
Patent IL-106918-A0 (IL)
Title: Electrically balanced connector assembly
IPC: G02B6/38
Filed: 1993-09-06
Abstract: The electrically balanced connector assembly comprises a printed circuit board including integrally defined capacitive elements designed to compensate for reactive imbalance of electrical components connected to it. A pair of wire termination blocks mounted to a first side of the circuit board are connected by circuitry on the circuit board to a corresponding pair of modular jacks mounted to a second side of the circuit board. The capacitive elements are connected between selected leads of the modular jacks and the wire termination blocks by the circuitry. The circuit board assembly is mounted in a panel yoke which includes a pair of apertures for allowing access to the modular jacks aligned in them. The apertures and circuit board assembly are orientated to allow connecting modular cords to gravity feed into and from the modular jacks. The panel yoke includes a device for snap-lockingly securing the panel yoke to a panel or a wall plate.
Patent IL-106976-A0 (IL)
Title: Nutrition for persons undergoing radiation therapy and/or chemotherapy
IPC: A61K38/17
Filed: 1993-09-10
Abstract: An enteral nutritional product has been formulated for persons who are currently undergoing radiation therapy and/or chemotherapy. The nutritional product has a protein system which includes a soy protein hydrolysate. The nutritional product is very low in folic acid, contains  beta -carotene, and has a ratio of n-6 to n-3 fatty acids that is in the range of about 1.3:1 to 2.5:1.
Patent IL-109197-A0 (IL)
Title: Liquid concentrated herbicidal glyphosate compositions
IPC: A01N57/20
Filed: 1994-04-01
Abstract: There is disclosed a liquid concentrate herbicidal composition comprising: at least 15% by weight based on the total composition of N-phosphonomethylglycine or of a salt thereof or of a mixture of salts thereof (calculated as acid equivalent); a water-insoluble diphenyl ether type herbicide (oxyfluorfen or acifluorfen) in the ratio by weight of N-phosphonomethylglycine a.e. to diphenyl ether type herbicide of from about 10:1 to about 100:1; about 5 to about 25% by weight of a surface active component comprising a mixture of an alkoxylated fatty amine with a surfactant chemically different from the alkoxylated fatty amine; 0 to about 10% by weight of solvent, the surface active component optionally with admixture of the solvent being capable of dissolving the diphenyl ether herbicide; about 1 to about 25% by weight of a compatibility agent; and water if necessary to total 100%.
Patent IL-111078-A0 (IL)
Title: Inhibitors of beta-amyloid protein production
IPC: C07C237/22
Filed: 1994-09-29
Abstract: This invention relates to compounds and pharmaceutical compositions, and methods for inhibiting or preventing the amyloid protein deposits in the brain which are associated with Alzheimer's disease and aged Down's syndrome patients. More particularly, it relates to the treatment of Alzheimer's disease.
Patent IL-123559-A0 (IL)
Title: Process for preparing benzyl-substituted rhodanine derivatives
IPC: C07C323/60
Filed: 1996-09-03
Abstract: The instant invention provides a novel process for preparing benzyl-substituted rhodanine derivatives. Also provided are novel benzyl-substituted thiolamides and benzyl-substituted hemithioacetals. Such compounds are useful as intermediates in preparing the compounds by the process of the instant invention.
Patent IL-130988-A0 (IL)
Title: Symmetrical polyurea-urethane fertilizer encapsulation
IPC: C08G18/32
Filed: 1999-07-20
Abstract: This invention relates to processes for the production of symmetrical polyurea-urethane coated granular fertilizer products, and to the symmetrical polyurea-urethane coated granular fertilizer products produced by these processes. These processes comprise coating fertilizer granules with compounds which react to form urethane coatings which contain terminal isocyanate groups, followed by polymerization of these urethanes to form symmetrical polyurea-urethanes. Suitable compounds comprise a) an organic polyisocyanate component, and b) an alkanol-amine component containing at least one tertiary amine group and at least one hydroxyl group. These compounds are present in sufficient quantities that the molar ratio of isocyanate groups to isocyanate-reactive groups is from about 1.6:1.0 up to about 10.0:1.0 in each encapsulating layer. It is necessary that sufficient amounts of these compounds are applied to the fertilizer granules such that the symmetrical polyurea-urethane coated granular fertilizer particles contain from about 0.5 to about 15% by weight of polyurea-urethane, based on the total weight of the encapsulated fertilizer particles.
Patent IL-143933-A0 (IL)
Title: Die cast superalloy articles
IPC: C22C19/05
Filed: 1999-12-22
Abstract: A die cast article (10) composed of a nickel or cobalt base superalloy is disclosed, and is characterized by a microstructure having an absence of flowlines, and a fine average grain size relative to corresponding forged or investment cast articles. The articles include gas turbine engine components.
Patent IL-147575-A0 (IL)
Title: Method for purifying keratinocyte growth factors
IPC: C07K14/50
Filed: 2002-01-10
Abstract: The present invention concerns the purification of keratinocyte growth factors.
Patent IL-151150-A0 (IL)
Title: Multiparticulate drug form comprising at least two differently coated pellet forms
IPC: A61P1/00
Filed: 2001-03-09
Abstract: The invention relates to a multiparticulate drug form suitable for uniform release of an active pharmaceutical ingredient in the small intestine and in the large intestine, comprising at least two forms of pellets A and B which comprise an active pharmaceutical ingredient in the core and have different polymer coatings which determine the release of the active ingredient at different pH values, characterized in that pellet form A is provided with an inner polymer coating which enables continuous release of active ingredient, and has an outer enteric coating which rapidly dissolves above about pH 5.5, and pellet form B is provided with a polymer coating which, in the USP release test, releases less than 20% of the active ingredient at pH 6.8 in 6 hours and releases more than 50% of the active ingredient at pH 7.2 in 6 hours. The invention additionally relates to a process for producing the multiparticulate drug form and to the use of pellet forms A and B for producing the drug form.
Patent IL-164396-A0 (IL)
Title: 2-Thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
IPC: A61P25/04
Filed: 2003-04-09
Abstract: The present invention relates to compounds of 2-thia-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-alpha(TNF-alpha) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
Patent IL-166146-A0 (IL)
Title: A strain of e.coli
IPC: C12R1/19
Filed: 2005-01-04
Abstract: The present invention relates to novel strains of Escherichia coli and fermentation processes involving these microorganisms. More specifically, the present invention relates to genetically-modified Escherichia coli strains and the use thereof for the production of the amino acids, particularly members of the aspartate family of amino acids such as threonine. The present invention also relates to methods of preparing E. coli strains for use in the fermentative production of amino acids.
Patent IL-173422-A0 (IL)
Title: Structure and method of making strained semiconductor cmos transistors having lattice-mismatched source and drain regions
IPC: H01L21/8238
Filed: 2006-01-30
Abstract: A process is provided for making a PFET and an NFET. Areas in a first semiconductor region adjacent to a gate stack are recessed. A lattice-mismatched semiconductor layer is grown in the recesses to apply a strain to the channel region of the PFET adjacent thereto. A layer of the first semiconductor material can be grown over the lattice-mismatched semiconductor layer and a salicide formed from the layer of silicon to provide low-resistance source and drain regions.
Patent AP-2002002677-A0 (AP)
Title: An apparatus called the toilet device, for collecting separately and keeping separately urine and for collecting separately and keeping separately faeces, for use in a toilet, and the method of manufacture of the said toilet plate device.
Inventor: SHAH CHANDU
Filed: 2002-04-18
Abstract: A Toilet Plate Device of any design with a substantially rectangular shape and of any dimensions, designed to incorporate as integral part of the Toilet Plate Device, moulded-in Cavity (B) for urine collection, a moulded-in throughhole (C) of any dimensions for urine disposal through a flexible plastic pipe and a moulded-in Faeces Drop Hole (D) for Faeces Drop and optional hole (E) for fastening the (optional) lid shown in Figures 4, 5, and 6 also made form polyethylene or other polymer by rotational moulding process, for covering the Drop Hole (D) of the toilet Plate device the said Toilet Plate Device and optional lid being made of polyethylene and/or foamed polyethylene and/or other suitable polymer and/or foamed polymer (if desired) with an additional stiffening agent such as fibre glass by rotational moulding process or other suitable plastic moulding process.
Patent AU-2003900944-A0 (AU)
Title: Cell isolation & enrichment
IPC: G01N15/04
Filed: 2003-02-28
Abstract: Fetal cells are enriched from cervical samples such as Pap smears by a combination of density gradient separation and antibody-mediated positive or negative selection. Typically, sequential density gradient enrichment steps are performed using preformed discontinuous density gradients that enrich fetal cells having a buoyant density between 1.033g/mL and 1.131g/mL Antibody-mediated positive selection is typically used, which method includes sequential magnetic bead enrichment of fetal cells that express first and second fetal cell antigens. Fetal cells isolated according to the invention may be used for subsequent genetic analysis or other biochemical, immunological or molecular analyses that assist in determining sex, predisposition to genetic disease, paternity and the like.
Patent MA-24929-A1 (MA)
Title: Piedestal pour armoires d'interconnexion et de distribution telephonique
Inventor: DE PENA FRANCISCO JAVIER
IPC: H04M1/00
Filed: 1999-07-13
Abstract: IL EST CONSTITUÉ D'UN CORPS PRÉFABRIQUÉ,  CREUX ,  QUI CONFIGURE UNE SORTE DE BOiTE OUVERTE à LA PARTIE INFÉRIEURS,  à LA BASE SUPÉRIEURE ET FERMÉE DUQUEL EST DÉFINIE  UNE  SURFACE  PLANE D'APPUI ET DE FIXATION POUR L'ARMOIRECORRESPONDANTE,  VERS LAQUELLE  S'OUVRE UN CERTAIN NOMBRE DE CONDUITS OU DE COUDES QUI ÉMERGENT à L'EXTÉRIEUR PAR LA ZONE INFÉRIEURE DE LA PAROI FRONTALE DU CORPS,  Ou ILS SE TERMINENT PAR DES MOYENS D'ACCOUPLEMENT POUR LES TUYAUX DE CANALISATION.
Patent MA-25406-A1 (MA)
Inventor: SHIN SONG SEOK
IPC: A61P29/00
Filed: 2001-10-12
Abstract: The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.
Patent MA-27064-A1 (MA)
Inventor: LAUFERSWEILER MATTHEW JOHN
IPC: C07D491/113
Filed: 2004-03-10
Abstract: The present invention relates to compound which are capable of preventing the extracellular release of inflammatory cytokines, said compounds, including all enantiomeric and diasteriomeric forms and pharmaceutically acceptable salts thereof, have the formula:wherein R comprises ethers or amines;R<1 >is:a) substituted or unsubstituted aryl; orb) substituted or unsubstituted heteroaryl;R<2a >and R<2b >units are each independently hydrogen, ethers, amines, amides, carboxylates, or said units can form a double bond, a carbonyl, or R<2a >and R<2b >can be taken together to form a substituted or unsubstituted ring comprising from 4 to 8 atoms, said ring selected from the group consisting of:i) carbocyclic;ii) heterocyclic;iii) aryl;iv) heteroaryl;v) bicyclic; andvi) heterobicyclic.
Patent MA-47566-A1 (MA)
Title: Utilisation de l'il-17 comme marqueur pronostique dans le cancer du sein
Inventor: BADOU ABDELLAH
IPC: G01N33/574
Filed: 2019-12-03
Abstract: L’il-17 est une cytokine sécrétée par de nombreuses cellules immunitaires, notamment la sous-population de cellules t de type th17. Dans cette étude, nous avons évalué la signification clinique de l'il-17 en tant que biomarqueur dans différents sous-types moléculaires de cancer du sein, notamment celui exprimant ou pas le récepteur d’estrogène (er- versus er+). La relation entre l'expression de l'il-17 et distincts facteurs clinicopathologiques a également été évaluée. Ainsi, nous avons étudié le niveau d’expression de l’il-17 au niveau de la tumeur, d’abord à l’échelle de l’arnm. L’expression de l’il-17 s’est avérée statistiquement plus importante comparée au tissu adjacent non-envahi (utilisé comme contrôle). Nous avons ensuite, associé la surexpression aux différents paramètres clinico-histopathologiques. En effet, il a été décrit que les cancers du sein triples négatifs (tnbc) et her2+ étaient associés à un mauvais pronostic, et que les cancers du sein de type luminal (a et b) étaient associés à un bon pronostic. Dans notre étude la surexpression de l’il-17 était observée chez les patientes erqui regroupaient également les patientes tnbc et her2+. Ce résultat a été remarquablement confirmé à l’échelle protéique (par immunohistochimie) où nous avons pu montrer que l’il17 présentait un marquage plus intense chez les patientes er- comparées aux patientes er+. De plus, le marquage il-17 était plus intense pour les grades avancés de la tumeur et pour les tumeurs avec un niveau élevé du marqueur de prolifération cellulaire ki67. Nous proposons ainsi l’utilisation de la cytokine il-17 comme un marqueur pronostique dans le cancer du sein.
Patent UY-23088-A1 (UY)
Inventor: DAVID ALAN ROBERTS
IPC: A61P33/02
Filed: 1990-06-14
Abstract: The invention provides N-phenylpyrazole derivatives of the formula:   <CHEM> wherein R<1> represents alkyl optionally substituted by halogen, R<2> represents alkyl, alkenyl or alkynyl optionally substituted by halogen, R<3> represents a phenyl group substituted in the 2-position by halogen; in the 4-position by optionally halo substituted alkyl or alkoxy; and optionally in the 6-position by halogen; and m and n are independently 0, 1 or 2; which are active against arthropod, plant nematode, helminth and protozoal pests.
Patent UY-23811-A1 (UY)
Title: Filtro de aire para motores y diferentes maquinas
IPC: F02M35/00
Filed: 1994-07-26
Abstract: Esta patente de invención se trata de filtros de aire para motores y diferentes mñáquinas, constituida por una parte denominada carcasa y un elemento filtrante. La primera, inyectada preferentemente en PI poliuretano, tiene las caras superior e inferior munidas de detalles en forma de labios de obstaculización y esta constituida por dos sectores: uno superior y uno inferior, ambas en forma de disco o anillos, especialmente interligados en forma de discos o anillo, espaciadamente interligados entre sí, de modo que entre ellos se pueda crear un encaje para el elemento filtrante, dicha carcasa podrá presentar un formato del circular, como ser cuadrado, rectangular u oval, formato que va acompañado o por los sectores (4-4') y por el elemento foltrante, este último en pieza de espuma, preferentemente de poliuretano expandido con una densidad adecuada. Cada una de las diez hojas presenta, sobre la parte superior derecha, en forma perforada.
Patent UY-25403-A1 (UY)
Title: Revestidor y preforma
Inventor: RICHARD C DARR
IPC: B65D1/02
Filed: 1999-02-24
Abstract: Revestidor interno mejorado para fabricar una preforma de plástico con fondo cerrado, una parte inferior integral que se extiende hacia arriba de dicha parte inferior e integrada a la misma, y una parte superior integral sustancialmente cilíndrica que se extiende hacia arriba inferior e integrada a la misma, teniendo dicha parte superior una porción superior con un sello abierto y con un reborde superior; el revestidor incluye además una superficie interior, una superficie exterior, y un medio de montaje integral que se proyecta hacia el interior desde la superficie interior para facilitar el encastre del revestidor con proyección interna; el revestidor además puede incluir un medio de ventilación para permitir el escape de gas desde la superficie interior del revestidor cuando el revestidor está fijado a dicha proyección interna. Se incluye también una preforma de plástico de múltiples capas para fabricar un recipiente por soplado que comprende un revestidor como el descrito anteriormente, que además incluye una superficie interior, una superficie exterior, y un medio de montaje para facilitar el encastre del revestidor con una porción macho del molde.
Patent UY-30478-A1 (UY)
Title: Sistemas de almacenamiento
Inventor: JONES PHILIP HAROLD NUKUTAURUA
IPC: E04H6/18
Filed: 2007-07-11
Abstract: Estructura para almacenar vehículos, para estacionamiento compacto y puesta en garaje de vehículos. Las modalidades preferidas comprenden uno o más arreglos bidimensionales de bahías de estacionamiento a las cuales se accede por uno o más carros móviles capaces de levantar y transferir vehículos hacia o desde bahías de estacionamiento. Incluye transportadores, donde descansa el un vehículo, en la plataforma de levantamiento de carros, las bahías de estacionamiento, y los puntos de carga y acceso para vehículos a la estructura de almacenamiento. Los transportadores permiten mover los vehículos por el sistema, sin retrasar los que se conducen bajo su propia potencia.
Patent ES-173824-A1 (ES)
Title: UN INSTRUMENTO BINOCULAR DE OBSERVACIoN.
IPC: G02B7/12
Filed: 1946-06-01
Abstract: Un instrumento óptico que tiene oculares gemelos montados en un cuerpo común, caracterizado por que un ocular va fijo al cuerpo, al paso que el otro se mueve en el mismo para poder regular la distancia interocular.
Patent ES-175399-A1 (ES)
Title: Un interruptor térmico
IPC: H05B41/06
Filed: 1946-10-22
Abstract: Interruptor térmico para el control de los circuitos de las lámparas de descarga eléctrica a baja presión que contienen contactos cooperantes uno de los cuales por lo menso va montado en un elemento bimetálico caracterizado porque a la temperatura ambiente este elemento tiene forma cóncava estando las partes de semejantes de este elemento dispuestas de tal manera que cuando el elemento alcanza la temperatura de funcionamiento deseada la concavidad se invierte súbitamente provocando un movimiento relativo rápido entre los contactos.
Patent ES-178729-A1 (ES)
Title: Mejoras relacionadas con osciladores controlados por cristal
IPC: H03C3/16
Filed: 1947-07-02
Abstract: Mejoras relacionadas con osciladores controlados por cristal caracterizadas por la combinación en un oscilador de un primer dispositivo electrónico que tenga un cátodo, una placa o ánodo y un electrodo de control; un segundo dispositivo electrónico que tenga un cátodo, una placa o ánodo y un electrodo de control; los aparatos que constituyan una fuente de energía eléctrica para los referidos dispositivos electrónicos; conjunto de circuito incluyendo impedancias conectadas de tal forma que la caída de tensión a través de ellas varíe con la corriente que circule a través del primer dispositivo electrónico citado y conectados también entre el cátodo y el electrodo de control del segundo dispositivo electrónico citado, por medio de los cuales un cambio en la corriente que circula a través del referido primer dispositivo electrónico, produzca un cambio opuesto en la polarización del electrodo de control del referido segundo dispositivo electrónico, y un filtro paso-banda que conecta la placa o ánodo del segundo dispositivo electrónico citado al electrodo de control del primer dispositivo electrónico citado por medio del cual se cebará una oscilación a la frecuencia deseada.