baber/WOPTO huggingface dataset:
Patent MX-2021005949-A (MX)
Title: STABLE VACCINE AGAINST <i>CLOSTRIDIUM DIFFICILE.
Inventor: PEREIRA CLANEY LEBEV
IPC: A61K39/08
Filed: 2019-11-22
Abstract: The present invention relates to a synthetic saccharide of general formula (I) that is related to <i>Clostridium difficile</i> PS-II cell-surface polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with <i>Clostridium difficile</i>. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against <i>Clostridium difficile</i> bacteria.
Patent MX-2021007178-A (MX)
Title: Quinoline derivatives for use in the treatment or prevention of cancer.
Inventor: EHRLICH HARTMUT
IPC: A61K31/4709
Filed: 2019-12-19
Abstract: The present invention concerns a compound of formula (Ib') or anyone of its metabolites or a pharmaceutically acceptable salt thereof f for use for treating and/or preventing cancer and/or dysplasia (Ib') wherein R is independently hydrogen, halogen, -CN, hydroxyl, (C<sub>1</sub>-C<sub>3</sub>)fluoroalkyl, (C<sub>1</sub>-C<sub>3</sub>)fluoroalkoxy, (C<sub>3</sub>-C<sub>6</sub>)cycloalkyl, -NO<sub>2</sub>, -NR<sub>1</sub>R<sub>2</sub>, (C<sub>1</sub>-C<sub>4</sub>)alkoxy, phenoxy, -NR<sub>1</sub>-SO<sub>2</sub>-NR<sub>1</sub>R<sub>2</sub>, -NR<sub>1</sub>-SO<sub>2</sub>-R<sub>1</sub>, -NR<sub>1</sub>-C(=O)-R<sub>1</sub>, -NR<sub>1</sub>-C(âO)-NR<sub>1</sub>R<sub>2</sub>, -SO<sub>2</sub>-NR<sub>1</sub>R<sub>2</sub>, -SO<sub>3</sub>H, -O- SO<sub>2</sub>-OR<sub>3</sub>, -O-P(âO)(OR<sub>3</sub>)(OR<sub>4</sub>), -O-CH<sub>2</sub>-COOR<sub>3</sub>, (C<sub>1</sub>-C<sub>3</sub>)alkyl, said alkyl being optionally mono- or di-substituted by a hydroxyl group, a -A-(CH<sub>2</sub>)m-B-NRaRb group, or a -(O-CH<sub>2</sub>-CH<sub>2</sub>)<sub>p</sub>-O-Ra group. The present invention also relates to a compound of formula (IVb') or a pharmaceutically acceptable salt thereof for use for treating and/or preventing cancer and/or dysplasia.
Patent MX-2021007353-A (MX)
Title: Generation of organoid-primed t (opt) cells with memory phenotype.
Inventor: HIDALGO MANUEL
IPC: A61K49/18
Filed: 2019-12-18
Abstract: A cell culture platform that uses a combination of sophisticated tissue engineering technologies to co-culture patient-derived tumor cells and the patient's own immune cells and create the conditions for expansion of tumor targeting T cells in culture. The platform can be used, e.g., for personalized medicine.
Patent MX-2021011489-A (MX)
Title: Anti-claudin 18.2 antibody and application thereof.
Inventor: TAO WEIKANG
IPC: A61P35/00
Filed: 2020-03-31
Abstract: The present disclosure relates to an anti-Claudin 18.2 antibody and an application thereof. Specifically, the present invention relates to an anti-Claudin 18.2 antibody, a mouse-derived antibody, chimeric antibody, humanized antibody and antigen-binding fragment thereof which contain a CDR of the anti-Claudin 18.2 antibody, and a use thereof as a medicine. In particular, the present disclosure relates to a use of the anti-Claudin 18.2 antibody in the preparation of a drug for treating Claudin 18.2 positive diseases or disorders.
Patent MX-2021012665-A (MX)
Title: Spring steel sleeve design.
Inventor: SERRURIER DOUGLAS C
IPC: E02F9/28
Filed: 2020-03-12
Abstract: A spring (400) includes a first spring arm (428) extending from the first side edge (418) of the flat base (406'), the first spring arm (428) including a first arcuate portion (430) extending from the flat base (406'), a first straight portion (432) extending from the first arcuate portion (430) and disposed proximate to the rear face (416), the first straight portion (432) defining a first obtuse angle (434) with the rear face (416), and a first straight portion length (436).
Patent MX-2021012871-A (MX)
Title: Generation of antibody-derived polypeptides by polypeptide chain exchange.
Inventor: GEORGES GUY
IPC: C07K16/46
Filed: 2020-04-24
Abstract: The present invention relates to a set of heterodimeric polypeptides and its uses, e.g. for generating multispecific antigen binders by polypeptide chain exchange.
Patent MX-2021012988-A (MX)
Title: Methods and systems for microsatellite analysis.
Inventor: GARNER HAROLD
IPC: C12Q1/6883
Filed: 2020-04-21
Abstract: The present disclosure provides methods and systems for classifying microsatellite and minor alleles in a sample. Also, the present disclosure provides methods and systems for generating classifiers for conditions based on microsatellite loci and for performing pan-cancer assays. The methods and systems can involve next-generation sequencing of nucleic acid samples from subjects and genotyping microsatellite loci in the samples.
Patent MX-2021014197-A (MX)
Title: Height, depth and circumferential adjustment mechanisms for cervical collar.
Inventor: BEJARANO ROBERT
IPC: A61F5/055
Filed: 2020-05-20
Abstract: Cervical collars, components thereof, and methods of using them overcome issues with conventional cervical collars.
Patent MX-2022003291-A (MX)
Title: Synthetic dna vectors and methods of use.
Inventor: SCHNEPP BRUCE C
IPC: A61K39/00
Filed: 2020-09-18
Abstract: Provided herein are isolated DNA vectors comprising a heterologous gene, wherein the DNA vector is devoid of bacterial plasmid DNA and/or bacterial signatures, which can abrogate persistence in vivo. The invention also features pharmaceutical compositions (non-immunogenic pharmaceutical compositions) including the DNA vectors of the invention, which can be used for induction of long-term, episomal expression of a heterologous gene in a subject. The invention involves methods of treating a subject by administering the DNA vectors of the invention, including methods of treating disorders associated with a defect in a target gene.
Patent MX-2022006945-A (MX)
Title: Treatments of diabetic macular edema and impaired visual acuity.
Inventor: SMITH MICHAEL DAVID
IPC: A61K31/166
Filed: 2020-12-09
Abstract: The present invention relates to treatments of diabetic macular edema (DME) and impaired visual acuity, comprising intravitreally administering the compound of formula (A) (or a pharmaceutically acceptable salt and/or solvate thereof): Formula (A).
Patent MX-2022011577-A (MX)
Title: Pro-adrenomedullin or fragment thereof in patients infected with corona virus and treatments with binder against adrenomedullin.
Inventor: BERGMANN ANDREAS
IPC: G01N33/68
Filed: 2021-03-15
Abstract: Subject matter of the present invention is a method for (a) diagnosing or predicting the risk of life-threatening deterioration or an adverse event or (b) prognosing the severity or (c) predicting or monitoring the success of a therapy or intervention in a patient infected with a Corona virus, the method comprising: - determining the level of pro-Adrenomedullin (SEQ ID No. 31) or fragment thereof in a sample of bodily fluid of said patient, - comparing said level of pro-Adrenomedullin or fragment thereof to a pre- determined threshold or a previous level of pro-Adrenomedullin or fragment thereof, and - correlating said level of pro-Adrenomedullin or fragment thereof with the risk of life-threatening deterioration or an adverse event, or - correlating said level of pro-Adrenomedullin or fragment thereof with the severity, or - correlating said level of pro-Adrenomedullin or fragment thereof with the success of a therapy or intervention, wherein said pro-Adrenomedullin or fragment thereof is selected from the group consisting of PAMP (SEQ ID No. 32), MR-proADM (SEQ ID No. 33), ADM-NH2 (SEQ ID No. 20), ADM- Gly (SEQ ID No. 21) and CT-proADM (SEQ ID No. 34). Subject matter of the present invention is an Anti-adrenomedullin (ADM) antibody or anti- ADM antibody fragment or anti-ADM non-Ig scaffold for use in therapy or intervention in a patient in a patient infected with a Corona virus.
Patent MX-2022013223-A (MX)
Title: [1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS.
Inventor: ENGELHARDT HARALD
IPC: A61P35/00
Filed: 2021-04-07
Abstract: The present invention relates to new [1,3]diazino[5,4-d]pyrimidines and derivatives of Formula (I), wherein the groups R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup> have the meanings given in the claims and specification, their use as inhibitors of HER2 and its mutants, pharmaceutical compositions which contain such compounds and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
Patent MX-2022015233-A (MX)
Title: Production of desaturated fatty alcohols and desaturated fatty acyl acetates in yeast.
Inventor: BORODINA IRINA
IPC: C12N9/02
Filed: 2019-06-14
Abstract: The present invention relates to the production of compounds comprised in pheromones, in particular moth pheromones, such as desaturated fatty alcohols and desaturated fatty acyl acetates and derivatives thereof, from a yeast cell.
Patent MX-PA00001499-A (MX)
Title: Medium-voltage circuit-breaker and disconnector module, and a corresponding power distribution substation.
Inventor: THIERRY STARCK
IPC: H02B13/02
Filed: 2000-02-11
Abstract: The module comprises a metal enclosure constituting a metal-clad housing receiving a multipole circuit-breaker and disconnector units where disconnection is performed by tilting the set of poles away from an in-service position in which each pole is simultaneously connected to two current feedthroughs projecting through the top wall of the housing. The distribution substation comprises a metal enclosure constituting a metal-clad housing that is subdivided into compartments serving specifically to house three multipole circuit-breaker and disconnector units in parallel alignment between two feeders. The poles of the units are interconnected via current feedthroughs passing through intermediate compartments, each of which has a feeder terminating therein.
Patent MX-PA01003269-A (MX)
Title: Hollow solid generated by rotation and method for making same.
Inventor: DEBALME JEAN-PAUL
IPC: B29C53/80
Filed: 1999-10-20
Abstract: The invention concerns a hollow solid (1) generated by rotation whereof the wall comprises a first inner zone (a) made, at least on its outer periphery, of a single thermoplastic material A, and a second zone comprising a first part (b) arranged continuously with the first zone (a) and made of a thermoplastic material identical with material A and continuous glass yarns embedded in said thermoplastic material and a second part (c) forming the hollow body outer periphery and made only of thermoplastic material. The invention is characterised in that the wall has a vacuum volume proportion VV less than 0.5 %, preferably less than 0.2 %.
Patent MX-PA01010516-A (MX)
Title: Floating cover for large liquid reservoir.
Inventor: CLAUDE J DEGARIE
IPC: E04H4/10
Filed: 2001-10-17
Abstract: The floating cover has a floating grid anchored to the perimeter walls of t he reservoir, and floats over the liquid level inside the reservoir. The floati ng grid comprises a flexible keel member and an array of flexible buoyant beams affixed to the keel member. A flexible impermeable membrane is affixed to the perimeter wall and is loosely laid over the floating grid. An array of flexible weight lines is anchored to the perimeter walls and is loosely laid over the impermeable membrane. Each weight line is laid at about halfway between an adjacent pair of buoyant beams. The floating grid, the impermeable membrane and the array of weight lines constitute three separate layers that are movable relative to each other without generating destructiv e stress in the impermeable membrane.
Patent MX-PA01011302-A (MX)
Title: Combination therapies for the stimulation of bone growth.
Inventor: VISHWAS MADHAV PARALKAR
IPC: A61K31/425
Filed: 2001-11-06
Abstract: This invention relates to pharmaceutical combinations of a prostaglandin agonist and a HMG-CoA reductase inhibitor, methods of using such combinations and kits containing such combinations. The pharmaceutical combinations, methods and kits are useful to enhance bone formation in mammals, including humans.
Patent MX-PA01011715-A (MX)
Title: Packaged absorbent paper product, container, and dispensing method.
Inventor: HERB F VELAZQUEZ
IPC: B65D83/08
Filed: 2001-11-15
Abstract: A product comprising an absorbent paper material and a container for use as a dispenser, which is adapted to hanging from a support member, such as a towel bar, is disclosed. The container can be optionally located on a surface, such as a counter top, and used as a dispenser. This provides the container with two different dispensing modes. The container has a hanger member integral with the container on one end, and the hanger member is attachable to the container in at least two separate positions. The hanger member is also adapted to covering at least a portion of the absorbent paper material exposed by an opening into the container prior to hanging the container.
Patent MX-PA02003508-A (MX)
Title: Electrostatic deposition formulations.
Inventor: SWEI GWO SHIN
IPC: C09K3/14
Filed: 2000-08-30
Abstract: Fine abrasive powders can be made more free flowing and better adapted to UP deposition in the production of coated abrasives by the control of the volume resistivity of the powder to a level that is not greater than 1014 ohms.cm by incorporation of a silica powder.
Patent MX-PA02005826-A (MX)
Title: Sanitary napkin with adjustable length intergluteal strip.
Inventor: MARINA NIKITINA
IPC: A61F13/15
Filed: 2002-06-12
Abstract: A sanitary napkin has a strip that extends rearwardly to reside in the intergluteal crevice. The pad is sized and configured to fit snugly against the wearer's body without penetrating the vaginal orifice. The strip provides improved body contact thus providing similar protection with a smaller pad and a discretion benefit to the user. The invention provides various alternative mechanisms for varying the length of the strip by the user.
Patent MX-PA02008135-A (MX)
Title: Bushing seal in a vacuum cleaner brush having a floor cloth.
Inventor: BYUNG-JO LEE
IPC: A47L9/02
Filed: 2002-08-21
Abstract: A vacuum cleaner brush having a case and a rotary element on which a floor cloth is attached. The rotary element is rotatably disposed on a lower portion of the case. A housing is disposed in the case, having a motor disposed therein, the motor rotatably driving the rotary element. A first and second bushing into which the driven shaft of the rotary element is provided with a blocking element protruding from a bottom surface of the case in the shape of a cylinder along a circumference of the first bushing for preventing dust and dirt from flowing into the first bushing. A ring element protrudes from an upper and inner circumference of the first bushing toward an outer circumference of the driven shaft, the ring element prevents dust and dirt from flowing into the housing. Dust and dirt are thereby prevented from flowing into the housing and damaging various components such as the motor and gears in the housing.
Patent MX-PA02008394-A (MX)
Title: Method and apparatus for manufacturing cement clinker from particulate cement raw material.
Inventor: HUNDEBOEL SOEREN
IPC: C04B7/44
Filed: 2001-01-19
Abstract: A description is made of a method as well as an apparatus for manufacturing cement clinker from particulate cement raw material by which method fresh raw material is preheated and possibly precalcined in a suspension preheater (1, 3) by heat exchange with hot exhaust gases, and preheated and possibly precalcined material is finally calcined and burned into clinker in a rotary kiln (7), hot clinker from the rotary kiln is cooled in a cooler (9) and dust is separated from the exhaust gases from the preheater in a filter arrangement (11). The method and the apparatus are peculiar in that dust from the filter arrangement (11) is introduced into the material inlet end of the rotary kiln (7) in a direction which is contrary to the flow direction of the kiln gases.Hereby is obtained a significant reduction of coatings on the walls of the riser duct.
Patent MX-PA02010319-A (MX)
Title: Improved luminescence characteristics detector.
Inventor: SETO MYRON
IPC: B44F1/12
Filed: 2002-01-26
Abstract: The invention discloses an improved method and a device implementing said method for the authentication of security documents or articles carrying luminescent marker compounds which show a time-deferred emission characteristic. The method allows a rapid extraction of characteristic luminescence parameters, such as emission intensity and time constants. The method is not sensitive to perturbations by ambient light and reduces the optical filtering requirements.
Patent MX-PA03000438-A (MX)
Title: Vapour deposition.
Inventor: VELTHUIS JOHANNES FRANCISCUS M
IPC: C23C14/24
Filed: 2001-07-17
Abstract: The invention relates to a process for applying a coating to a substrate wherein the coating is formed of at least two components or elements. In a preferred embodiment, the coating is formed of at least two metals. In accordance with the invention, the coating is applied by vapour deposition under choking conditions.
Patent MX-PA03004076-A (MX)
Title: Improved random packing element.
Inventor: NIKNAFS HASSAN S
IPC: B01J19/30
Filed: 2001-11-06
Abstract: The invention provides a novel improved packing element having the basic shape of a polygon with arches formed around the periphery by deforming the edge area in one direction and an area axially within the edge area to form arches projecting in the opposite direction and providing an axially located aperture. Such packing elements can be conveniently formed using a simple cutting and stamping operation.
Patent MX-PA03004119-A (MX)
Title: Process to improve polyurethane foam performance.
Inventor: EL GHOBARY HASSAN
IPC: C08G18/18
Filed: 2001-10-29
Abstract: An improved process to enhance polyurethane foam performance is described. Polyurethane foam is prepared by reactions between a polyisocyanate and an active hydrogen-containing component wherein said reactions are conducted in the presence of catalysts composed of (a) at least one specific tertiary amine carbamate (formed by the reaction of reactive tertiary amine and polyisocyanate) and, optionally, (b) salts formed by the reaction between the specific tertiary amine carbamate(s) and hydroxy- and/or halo-carboxylic acids. The specific tertiary amine carbamates in the subject invention are dimethylaminoethoxyethyl carbamate, bis(dimethylaminopropyl)amino-2-propyl carbamate, dimethylaminoethyl carbamate, and mixtures thereof.
Patent MX-PA03007667-A (MX)
Title: Basket carrier for bottles and blank therefor.
Inventor: HOLLEY JOHN M JR
IPC: B65D77/26
Filed: 2002-02-27
Abstract: An article carrier (C) of the basket type adapted to accommodate a plurality of articles, such as bottles (B). The carrier comprises a base (14, 18), opposed side (12, 20) and end walls (50, 52; 82, 84), and internal medial partition structure (74, 78) and handle means (H) by which the carrier can be lifted and carried. The bottles are received on both sides of the medial partition structure of the carrier. A pair of securing flaps (114, 116) are hinged to the medial partition structure and are secured to an end wall (84) of the carrier to create a joint between said medial partition structure and that end wall. The medial partition structure is formed from first and second medial partition panels (74, 78) hinged together along a first fold line (80). The first fold line is disposed inwardly of the carrier from said end wall (84) relative to a pair of second fold lines (118, 120) by which said securing flaps are hinged to one (74) of the first and second medial partition panels.
Patent MX-PA04000093-A (MX)
Title: Switch enclosure and operating handle apparatus.
Inventor: HENRY B JOINES
IPC: H01H9/26
Filed: 2003-12-19
Abstract: An enclosure and operating handle apparatus for a double throw switch is disclosed. An operating handle support defines two distinct switch compartments within the enclosure and supports an operating handle apparatus configured for selectively operating only one of two switches inside the enclosure at a time.
Patent MX-PA04003206-A (MX)
Title: Cushion body and foam resin particles for filling cushion body.
Inventor: YASUHIRO SAKODA
IPC: A47C27/12
Filed: 2002-10-11
Abstract: A cushion body and foam resin particles for filling in the cushion body capable of solving such a problem that, when the cushion bodies such as a bed, a mattress, a pillow, and a cushion are used for performing a cushioning function, noise is generated each time the cushion bodies are moved to provide uncomfortable feeling to users or awake the users while asleep, wherein foam resin particles with a specified average particle size containing a specified amount of fluidization accelerator are used as the filler for the cushion body.
Patent MX-PA04003512-A (MX)
Title: Carton with handle and blank thereof.
Inventor: JULIEN MERZEAU
IPC: B65D71/28
Filed: 2002-10-18
Abstract: A carton and blank (10) for forming a carton for holding a plurality of articles. The carton includes a series of hinged wall panels forming a sleeve including a top panel (16) and opposed side panels (14, 18) hingedly connected to the top panel (16). There further comprises a continuous strap handle (H) formed from the carton and transversely extending entirely across the top panel (16) and one of the side panels (14). The strap (H) is so connected at its opposite ends as to provide a surplus of material to enable a user part of the handle (H) to be brought into a position of use.
Patent MX-PA04005268-A (MX)
Title: Optical storage system, optical storage medium and use of such a medium.
Inventor: RONALD J A VAN DEN OETELAAR
IPC: G11B7/253
Filed: 2002-12-02
Abstract: A description is given of an optical storage system comprising an optical storage medium (1) and an optical head device (6). The medium has a substrate (2), a recording stack (3) and an optically transparent protective coating stack (4 and 5), for protecting the recording stack from impact by the optical head device (6). The protective coating stack comprises a multi-layer (4 and 5) of at least: a first layer (5) with a thickness smaller than 40 nm and a surface with a surface energy smaller than 1.5 J/m2, and a second layer (4), adjacent the first layer (5), with a Young's modulus E smaller than 10 GPa and larger than 0,001 GPa. This combination of layers (4 and 5) is very resistant to damage caused by mechanical impact of the optical head device (6). No lubricants are required.
Patent MX-PA04006382-A (MX)
Title: Balance system for single cylinder engine.
Inventor: WILLIAM D KOENIGS
IPC: F02B75/00
Filed: 2002-12-27
Abstract: A balance system (500) and method for balancing piston forces with a single cylinder internal combustion engine (100) are disclosed. The balance system (500) includes a crankshaft (220), a counterbalance assembly (445) and a groove (610). The crankshaft (220) includes a crankshaft portion (510), a crank arm (530), a crank pin (520), and an eccentric flange (550) adjacent to the crank arm (530). The counterbalance assembly (445) has a counterbalancing mass portion (570) and a coupling arm (580) that are fixed with respect to one another, and a pin (600) that protrudes from a side of the counterbalancing mass portion (570). The eccentric flange (550) supports the coupling arm (530). The groove (610) is capable of receiving the pin (600); where the pin (600) is capable of sliding along the groove (610) and also rotating within groove (610), so that the counterbalance assembly (445) is capable of rotating while moving toward and away from the crankshaft (220).