baber/WOPTO huggingface dataset:
Patent CA-3144900-A1 (CA)
Title: Nmda receptor constructs to detect and isolate nmdar autoantibodies
Inventor: KORNAU HANS-CHRISTIAN
IPC: C07K14/705
Filed: 2020-07-02
Abstract: The invention relates to a soluble N-methyl-D-aspartate receptor (NMDAR) protein construct comprising one or more NMDAR autoantibody epitopes, wherein the construct comprises an extracellular domain (ECD) of the NMDAR subunit GluN1 or a fragment thereof and an ECD of at least one of the NMDAR subunits GluN2A, GluN2B, GluN2C or GluN2D, or fragment thereof. Further, the invention relates to an in vitro method for the detection of NMDAR autoantibodies in a sample, the method comprising, a.) providing a sample suspected of comprising NMDAR autoantibodies, b.) providing a NMDAR protein construct of the invention as a capture molecule, c.) contacting said sample with said NMDAR protein construct, thereby binding NMDAR autoantibodies from said sample to said NMDAR protein construct, and d.) determining the presence and optionally the amount of bound NMDAR autoantibodies. In embodiments, the method of the invention is applied for the diagnosis, prognosis, disease monitoring, patient stratification and/or therapy monitoring of a medical condition associated with autoantibodies against the NMDAR, preferably anti-NMDAR encephalitis.
Patent CA-3145459-A1 (CA)
Title: Composition pharmaceutique de darolutamide
Inventor: ILMONEN SUSANNA
IPC: A61K9/20
Filed: 2020-07-02
Abstract: La présente invention concerne une composition pharmaceutique pour administration orale, en particulier sous la forme d'un comprimé, comprenant du darolutamide ou un sel pharmaceutiquement acceptable de celui-ci en tant que principe actif. Le darolutamide est un modulateur puissant du récepteur des androgènes (AR) utile dans le traitement du cancer, en particulier du cancer dépendant de l'AR tel que le cancer de la prostate, et d'autres maladies dans lesquelles l'antagonisme AR est souhaité.
Patent CA-3147282-A1 (CA)
Inventor: JAIN VISHIST KUMAR
IPC: A23G1/40
Filed: 2020-09-24
Abstract: The present invention relates to cocoa and/or malt beverage products comprising isomaltooligosaccharides and methods of producing such products. The products may be reduced in sugar compared to conventional cocoa and/or malt beverage products while providing a similar sweetness, texture and taste as the conventional products.
Patent CA-3148295-A1 (CA)
Inventor: SUN LI
IPC: A61P31/12
Filed: 2020-07-22
Abstract: The present invention falls within the biomedical field. Specifically, disclosed is a method for treating diseases based on an interferon, the method comprising intermittently administering a therapeutic agent based on an interferon to a subject, wherein the diseases are viral infections or cancers.
Patent CA-3148801-A1 (CA)
Title: Complement mineral comprenant des microbes destines a favoriser la croissance en agriculture
Inventor: SHASTRI PARSHURAM NIRAJAN
IPC: A01N25/02
Filed: 2020-07-24
Abstract: L'invention concerne un système et un procédé de préparation d'un complément microbien, et d'application du complément à des plantes, des arbres et d'autres articles en vue de favoriser leur croissance. Le complément comprend de l'eau de mer, notamment des microbes qui existent naturellement dans l'eau de mer. L'eau de mer recueillie contient des microbes dans un état inactif ou dormant. L'eau de mer subit un processus de filtration, de minéralisation et d'oxygénation en vue de réduire les taux de chlorure de sodium, d'augmenter les taux de minéraux souhaitables dans l'eau de mer et d'oxygéner l'eau de mer en vue de maintenir les microbes vivants, même dans un état dormant ou inactif. Les microbes sont maintenus dans un état inactif ou dormant à travers le processus de préparation, mais deviennent actifs lorsque le complément est appliqué à des plantes ou des arbres, ce qui favorise la croissance agricole.
Patent CA-3151260-A1 (CA)
Inventor: SCHLIPF BEN
IPC: A01C23/00
Filed: 2020-06-04
Abstract: Un système portable pour tester ou présenter un outil agricole comprend un boîtier (104) portant une alimentation électrique (206), une pluralité de coupleurs électriques (120) conçus pour recevoir des faisceaux de câbles associés à des dispositifs de test, un module de simulateur (214) conçu pour simuler au moins un paramètre de fonctionnement de l'outil agricole sur lequel des dispositifs de test sont portés, et un système de commande. Le système de commande comprend une interface utilisateur graphique (110) et un circuit de traitement couplé électriquement de manière fonctionnelle à l'interface utilisateur graphique (110) et aux faisceaux de câbles. Le circuit de traitement est conçu pour surveiller et afficher des informations concernant le fonctionnement des dispositifs de test. Un procédé de test ou de présentation d'un outil agricole comprend la connexion d'un dispositif de test à un coupleur électrique du système portable, l'envoi d'un signal de commande au dispositif de test, et la surveillance des performances du dispositif de test avec le système de commande. Le signal de commande est basé, au moins en partie, sur l'entrée de données.
Patent CA-3151570-A1 (CA)
Title: Sanitized chiller
Inventor: BEDARD MARK
IPC: F25D23/00
Filed: 2022-03-15
Abstract: A cooler comprising an outer container and an air recirculating system, the air recirculating system having a warm air intake, a cool air outlet arranged to discharge cooled air over any contents within the outer container, a fan to move air from the warm air inlet to the cool air outlet, a chiller positioned to cool air moving from the warm air intake to the cool air outlet, and a source of UVC light rays located such that air passing between the warm air inlet and the cool air outlet is exposed to such UVC light rays.
Patent CA-3153245-A1 (CA)
Title: Modular floor panel latching system
Inventor: URAM SCOTT
IPC: E04H4/08
Filed: 2022-03-23
Abstract: A latch system that attaches to a retractable load bearing pool cover. The latch system interconnects deployable and retractable load-bearing floor panels or pool cover panels that may be separable into individual sections for compact vertical stacking and storage when the panels are retracted.
Patent CA-3156328-A1 (CA)
Inventor: KENNEDY TIMOTHY E
IPC: C12N5/079
Filed: 2022-04-19
Abstract: The present disclosure concerns a cell or tissue culture system comprising a solid support for the culture of adherent cells or adherent tissues and a plurality of cationic dendrimers associated to the surface of the solid support. Each cationic dendrimer includes one or more functional amine group. The cationic dendrimer is protonated at physiological pH. The cell or tissue culture system can be used for the culture of adherent cells or tissues and be used for the differentiation of stem cells.
Patent CA-3157988-A1 (CA)
Inventor: REGAN CONNOR
IPC: F16C19/36
Filed: 2020-10-30
Abstract: In one aspect of the present disclosure, a wheel hub assembly is provided that includes a hub body having an outboard end portion and an inboard end portion, a bearing assembly, and a seal. The seal includes a seal case and a sleeve. The hub body and seal case are rotatable relative to the sleeve. The wheel hub assembly further includes a stop of the bearing assembly configured to resist movement of the sleeve toward the outboard end portion of the hub body as the hub body, bearing assembly, and sleeve are advanced together in an inboard direction along a vehicle spindle. The stop permits the bearing assembly to transfer a force applied in an inboard axial direction against the bearing assembly, such as by tightening of a spindle nut, to the sleeve and urge the sleeve along a vehicle spindle.
Patent CA-3158123-A1 (CA)
Title: Amide derivative and preparation method therefore and use thereof in medicine
Inventor: WEI YONGGANG
IPC: C07D409/12
Filed: 2020-11-12
Abstract: The present invention relates to an amide derivative and use thereof in medicine, and specifically to an amide derivative shown as general formula (I) or a stereoisomer, solvate, metabolite, deuteride, prodrug, pharmaceutically acceptable salt or cocrystal thereof, a pharmaceutical composition containing the same, and use of the compound or the composition disclosed herein in preparing an NLRP3 inhibitor
Patent CA-3158714-A1 (CA)
Inventor: CUKADAR BELGIN
IPC: A01H1/00
Filed: 2022-05-09
Abstract: The invention provides seeds and plants of cucumber hybrid DRCE9615, cucumber inbred line EUR-Y319-3065GY, and cucumber inbred line EUR-Y318-5035GY. The invention thus relates to the plants, seeds, plant parts, and tissue cultures of cucumber hybrid DRCE9615, cucumber inbred line EUR-Y319-3065GY, and cucumber inbred line EUR-Y318-5035GY  and to methods for producing a cucumber plant produced by crossing such plants with themselves or with another plant, such as a cucumber plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to plants, seeds, plant parts, and tissue cultures of cucumber hybrid DRCE9615, cucumber inbred line EUR-Y319-3065GY, and cucumber inbred line EUR-Y318-5035GY comprising introduced beneficial or desirable traits.
Patent CA-3160019-A1 (CA)
Title: Systeme de climatisation et de filtration
Inventor: KNOWLES GREGORY BRIAN
IPC: B60H3/06
Filed: 2020-11-30
Abstract: Système de climatisation et de filtration (10) comprenant un système de pré-traitement (12) pour filtrer initialement l'air aspiré depuis un environnement externe ; un moyen de pressurisation (50) pour mettre sous pression positive l'air filtré par le système de pré-traitement (12) et au moins un moyen de circulation (106). Chaque moyen de circulation (106) aspire de l'air depuis l'environnement externe à travers le système de pré-traitement (12) et le moyen de pressurisation (50) ainsi que de l'air provenant d'au moins une zone fermée (1) pour les combiner en un flux d'air. Le flux d'air est ensuite dirigé vers au moins un ensemble de moyens de filtration (94) et de moyens de climatisation (96) avant d'être transporté vers au moins une parmi la ou les zones fermées (1).
Patent CA-3161384-A1 (CA)
Inventor: ALFF DENIS
IPC: B60W40/13
Filed: 2020-12-11
Abstract: Disclosed is a method for ascertaining a load applied to a pneumatic tire casing of a mounted assembly, comprising the following steps: - acquiring a signal comprising the amplitude of the acceleration in the direction normal to the crown when rolling at the rotational speed W; - determining a reference acceleration; - identifying a series of increments I; - delimiting the signal between Imin and Imax for constructing a wheel revolution signal; - defining a first energy density S, which is a function of the wheel revolution signal, of the reference acceleration, designated S+ when the wheel revolution signal is greater than a threshold A and S- when it is not; - identifying the deformation Def% of the tire casing generated by the load as a function of the reference acceleration and the first energy density S; - determining the load Z applied using a bijection F comprising the deformation Def% of the tire casing.
Patent CA-3162110-A1 (CA)
Title: Providing a customer with a number of payment scenarios
Inventor: ANDERSON CHRIS
IPC: G06Q20/22
Filed: 2022-06-08
Abstract: A system and method for providing a customer with a number of payrnent scenarios is disclosed. The rnethod receives at a payment provider computing system an inquiry about a payment scenario for a customer, the inquiry including identification information for the customer, utilizes the identification information to perform a credit prescreen, and generates, based on a result of the credit prescreen, a plurality of payment scenarios with associated terms.  The plurality of payrnent scenarios with associated terms is then provided to the customer and the customer selects the desired payment scenario. An agreement with the associated terms of the payment scenario is generated and provided to the payment provider computing system. The mobile device provides the selected payment scenario to a retail computing systern during a checkout process and the transaction is completed.
Patent CA-3162830-A1 (CA)
Inventor: OTTEN DHR ANDY JOHANNA ELISABETH
IPC: H05B45/58
Filed: 2020-12-24
Abstract: An LED driver measures a voltage across the LED and a temperature associated with the LED. The LED driver drives the LED to operate below a knee in the voltage/current curve of the LED and derives an expected voltage across the LED from the temperature of the LED, the LED driving current, and a predetermined relation between the expected LED voltage and at least one of LED temperature and LED driving current. The LED driver determines if the measured voltage across the LED exceeds the expected voltage across the LED, and establishes, based on the determination, if an LED approaching end of life warning is to be generated. Thus, an approaching end of life may be determined by the LED driver while the LED is still operational.
Patent CA-3164128-A1 (CA)
Inventor: HUANG LIHONG
IPC: G06F21/12
Filed: 2021-07-07
Abstract: L'invention concerne un procédé et un appareil pour empêcher un repositionnement de micrologiciel d'un dispositif de traitement de données, et le dispositif de traitement de données. Le procédé consiste à permettre à un programme de chargement de démarrage de lire la valeur actuelle d'un bit prédéterminé dans une mémoire programmable une seule fois (101) ; à déterminer si la valeur actuelle et une valeur légitime écrite dans la mémoire programmable une seule fois après la mise à niveau la plus récente de micrologiciel d'un dispositif de traitement de données satisfont une relation prédéfinie (102) ; lorsqu'il est déterminé que la valeur actuelle et la valeur légitime satisfont la relation prédéfinie, à permettre au programme de chargement de démarrage d'appeler un noyau de système d'exploitation du dispositif de traitement de données (103) ; et lorsqu'il est déterminé que la valeur actuelle et la valeur légitime ne satisfont pas la relation prédéfinie, à permettre au programme de chargement de démarrage de ne pas appeler le noyau de système d'exploitation du dispositif de traitement de données (104).
Patent CA-3164451-A1 (CA)
Title: High resolution and high sensitivity pet scanner with pet detector modules
Inventor: LABELLA ANDREW
Filed: 2021-01-15
Abstract: The disclosure is directed to a device that includes a cavity formed by a plurality of rails, the plurality of rails connected to both a first support and a second support, each at predetermined intervals about a circumference of the first support and the second support; and at least one particle detection device operably connected to each rail of the plurality of rails. The disclosure is also directed to a scanner that includes the device, and a processor.
Patent CA-3165903-A1 (CA)
Inventor: KRUEGEL ANDREW CARRY
IPC: C07C211/35
Filed: 2020-12-28
Abstract: L'invention concerne des dérivés arylcyclohexylamine et leur utilisation dans le traitement de troubles psychiatriques.
Patent CA-3166969-A1 (CA)
Title: Affichage tete haute industriel
Inventor: PRIDIE STEVEN WILLIAM
IPC: G02B27/00
Filed: 2021-02-05
Abstract: La présente invention concerne un procédé de génération d'un affichage cible dans un environnement. Des données sont collectées et analysées depuis un ou plusieurs capteurs environnementaux pour déterminer une distance cible d'un point à l'intérieur du système à une zone d'affichage cible à l'intérieur de l'environnement. Une distance entre un projecteur et un miroir concave est modifiée pour ajuster une distance d'un plan focal à partir du point à l'intérieur du système afin de correspondre à la distance cible déterminée. Le plan focal est associé à l'affichage cible.
Patent CA-3168236-A1 (CA)
Inventor: MARK JOSEPH L
IPC: A61B90/00
Filed: 2015-03-04
Abstract: A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either device within the brain.
Patent CA-3171015-A1 (CA)
Title: Appareil et methode destines a chauffer un fluide dans une conduite au moyen d'un courant alternatif monophase
Inventor: SHUSTOV ANDREY
IPC: H05B3/42
Filed: 2021-02-12
Abstract: La présente invention concerne un dispositif (110) de chauffage d'un fluide. Le dispositif comprend au moins un pipeline électroconducteur (112) et/ou au moins un segment de pipeline électroconducteur (114) pour recevoir le fluide et au moins une source de courant alternatif monophasé et/ou au moins une source de tension alternative monophasée (126). Chaque pipeline (112) et/ou chaque segment de pipeline (114) est associé respectivement à une source de courant alternatif monophasé respectif et/ou à une source de tension alternative monophasée respective (126) qui est relié au pipeline respectif (112) et/ou au segment de pipeline respectif (114). La source de courant alternatif monophasé respectif et/ou la source de tension alternative monophasée (126) sont conçus pour générer un courant électrique dans le pipeline respectif (112) et/ou dans le segment de pipeline respectif (114), courant électrique qui réchauffe le pipeline respectif (112) et/ou le segment de pipeline respectif (114) par effet Joule qui se produit lorsque le courant électrique passe à travers le matériau de tuyau conducteur, afin de chauffer le fluide. La source de courant alternatif monophasé et/ou la source de tension alternative monophasée (126) sont reliés de manière électroconductrice au pipeline (112) et/ou au segment de pipeline (114) de telle sorte que le courant alternatif généré circule par l'intermédiaire d'un conducteur « aller » (128) dans le pipeline (112) et/ou le segment de pipeline (114) et retourne par l'intermédiaire d'un conducteur « retour » (130) à la source de courant alternatif et/ou de tension alternative (126).
Patent CA-3172470-A1 (CA)
Inventor: WHITEHOUSE ANDREWSTEVEN
IPC: A23G1/30
Filed: 2021-04-07
Abstract: La présente invention concerne des compositions d'agents de tropicalisation à base de graisse, des procédés pour leur préparation, des procédés de tropicalisation de chocolat ou d'analogues de celui-ci, et le chocolat ou des analogues de chocolat contenant les agents de tropicalisation.
Patent CA-3179358-A1 (CA)
Inventor: TURNER ROSS
IPC: B65F3/00
Filed: 2022-10-18
Abstract: A refuse vehicle includes a body coupled at least one of the frame and the chassis, a battery configured to provide electrical power to a first motor, a vehicle body supported by the chassis and defining a receptacle for storing refuse therein, an electric power take-off system coupled to the vehicle body, the electric power take-off system including a second motor configured to convert electrical power received from the battery into hydraulic power, one or more microphones coupled to the body and configured to detect noise, one or more speakers coupled to the body configured to emit noise reducing sounds, and a controller configured to receive data related to the detected noise from the one or more microphones and cause the one or more speakers to emit the noise reducing sounds in response to the data received from the one or more microphones.
Patent CA-3179850-A1 (CA)
Inventor: SWARTZ ASHLEY
IPC: G16H40/67
Filed: 2021-05-27
Abstract: A method of configuring a treatment regimen of one or more exoskeleton systems in an exoskeleton network, the method comprising: receiving exoskeleton data from one or more exoskeleton systems that are operably connected to a network; storing the exoskeleton data from the one or more exoskeleton systems; generating a configuration input for configuring at least one of the one or more exoskeleton systems the configuration input including a replacement for or update to a current medical treatment regimen being implemented by the at least one of the one or more exoskeleton systems; and sending the generated configuration input to the at least one of the one or more exoskeleton systems via the network to cause replacing or updating the current medical treatment regimen being implemented by the at least one of the one or more exoskeleton systems.
Patent CA-3184480-A1 (CA)
Inventor: WAWRLA ANDREAS
IPC: F25D31/00
Filed: 2021-05-28
Abstract: The invention relates to a tank system (1) for cooling, storing and removing a liquid, comprising a tank (2) for cooling the liquid and storing the liquid in a volume (V) along a stratification axis (L) of the volume (V) for thermal stratification along the stratification axis (L), wherein the tank (2) can be filled through a filling device (4) having a filling inlet (5) in an inlet region along the stratification axis (L) and can be emptied via an outlet in an outlet region opposite the inlet region along the stratification axis (L). For the purpose of flexible handling, in order to prevent mixing, the supplied liquid is conveyed into a flow, which extends completely or partly in a plane perpendicular to the stratification axis (L), and is supplied to the liquid stored in the tank (2), such that the flow runs tangentially to a circular arc that extends in a plane perpendicular to the stratification axis (L).
Patent CA-3184947-A1 (CA)
Inventor: WONDER BRUCE
IPC: C01F7/56
Filed: 2015-09-11
Abstract: Aluminum chlorohydrate products comprise particles of aluminum chlorohydrate in fractured crystal form, the particles having a basicity in the range of 0% to about 85.6 %, and a surface area to weight ratio of about 295 to about 705 m2/kg, inclusive of both endpoints and all numerical values therebetween, where the ratio is measured by laser diffraction. Methods of producing such products are also disclosed.
Patent CA-3185525-A1 (CA)
Title: Bispecific antibodies binding alk-1 and bmpr-2
Inventor: WEBER ERNST
IPC: C07K16/46
Filed: 2018-10-25
Abstract: The present invention relates to bispecific antibodies binding human ALK-1 and human BMPR-2. Also provided are BsABs which are agonists of ALK-1/BMPR-2 signaling, and BsABs which do not trigger osteogenic signaling. Furthermore, the invention relates to pharmaceutical uses of the BsABs, in particular for the treatment of pulmonary hypertension.  Also provided are methods to screen for BsABs for use in the therapy, e.g. of pulmonary hypertension.
Patent CA-3189749-A1 (CA)
Inventor: BLANCHARD DANIEL B
IPC: A61M39/10
Filed: 2021-07-30
Abstract: A valve connector for a tunable valve is disclosed, with tunable features to allow for optimization. The tunable valve can include slits, which may be preferentially placed, angled and sized to optimize the crack pressure, maintenance pressures, and clearance characteristics of the connector. The tunable valve may also include a recess in the area of an exemplary center slit, which may be sized further modify the characteristics of the connector valve. The valve may be preferentially curved along either a lateral axis or a transverse axis. The tunable valve may be a proximal valve that is capable of being secured between proximal housing and distal housing. The proximal housing opening may be preferentially shaped.
Patent CA-3190079-A1 (CA)
Inventor: WYATT TODD
IPC: H01C17/23
Filed: 2021-05-11
Abstract: L'invention concerne une pluralité de résistances. La résistance peut comprendre un ou plusieurs éléments résistifs et une pluralité de parties conductrices. Des ouvertures ou fentes, qui peuvent être configurées pour ajuster des valeurs de coefficient de température de la résistance (TCR) de la résistance, sont formées dans les éléments résistifs. La forme, la quantité et l'orientation des ouvertures ou fentes peuvent varier. Selon un aspect, des ensembles collecteurs sont prévus pour fixer ou maintenir des broches par rapport aux résistances.