baber/WOPTO huggingface dataset:
Patent DE-69227470-D1 (DE)
Inventor: SWANN LINSEY
IPC: A62B17/04
Filed: 1992-06-05
Granted: 1998-12-03
Abstract: The breathing system comprises a canister carrying layered filtering material, including activated carbon granules, a dessicant, a catalyst for the catalyzation of carbon monoxide to carbon dioxide, optionally lithium peroxide, for conversion of CO2 to O2, and electrostatically charged filters between the layers of filtering material. A mouthpiece carrying a noseclip, and inhalation and exhalation check valves and a whistle is disposed within a flexible, substantially completely transparent hear-through hood, both the mouthpiece and hood being disposed in the canister between the filtering material and a cover for the canister. In use, the cover is removed, air inlet apertures are uncovered, and the hood is drawn about an individual's head and substantially sealed about the neck. With the mouthpiece in the individual's mouth, and noseclip closing off the user's nose, inhalation causes air to flow through the filtering material and the inhalation check valve and past the exhalation check valves. When exhaling, the exhalation check valves open to permit exhaled air to flow into the hood. The inhalation valve closes during exhalation to prevent backflow of air through the filtering material. By exhaling into the hood, a slight positive pressure within the hood is established to prevent noxious gases, smoke particles and the like from entering the hood through the neck opening. A chemical light is provided externally on the canister.
Patent DE-69231106-D1 (DE)
Inventor: FAHY GREGORY M
IPC: A01N1/02
Filed: 1992-07-07
Granted: 2000-06-29
Abstract: A computer-controlled method for preparing organs for long-term preservation through the introduction of vitrifiable concentration of cryoprotectant and subsequently preparing organs for transplantation by the removal of the cryoprotectant comprises the steps of: (a) initially perfusing the organ without cryoprotectant; (b) adding a cryoprotectant solution to the organ and gradually elevating the cryoprotectant concentration to a first predetermined level while concurrently reducing the temperature of the organ; (c) delaying an increase in the concentration of said cryoprotectant for a time sufficient to permit approximate osmotic equilibrium of the organ to occur; (d) elevating the cryoprotectant concentration of said solution to a level, greater than said first predetermined level, required for vitrification and maintaining the solution at the elevated concentration for a time sufficient to permit approximate osmotic equilibrium of the organ to occur; (e) perfusing the organ with a reduced, non-vitrifiable concentration of cryoprotectant in combination with a nonpenetrating osmotic buffering agent for a time period sufficient to permit approximate osmotic equilibrium of the organ to occur; (f) washing out substantially all of the cryoprotectant while decreasing the concentration of the osmotic buffering agent to a second, nonzero level substantially below said first buffering agent concentration level and concurrently increasing the temperature of the organ; and (g) perfusing the organ to remove the osmotic buffering agent sufficiently to render the organ suitable for transplantation.
Patent DE-69231131-D1 (DE)
Inventor: KAWAGUCHI SUSUMU
IPC: F25B43/00
Filed: 1992-12-02
Granted: 2000-07-06
Abstract: A refrigeration device has a refrigeration circuit which uses a hydrofluorocarbon refrigerant and comprises a compressor (1), an evaporator (4) and an accumulator (5), in which the compressor uses a lubricating oil (e.g. hard akyl benzene oil) insoluble with the refrigerant. A compressor suction pipe (7) has an oil return hole (8) in the upper end portion portion thereof  and is inserted into the accumulator from below, and the evaporator outlet is connected to the upper end of the accumulator. <IMAGE>
Patent DE-69232556-D1 (DE)
Inventor: CASAS-PEREZ A
IPC: A61K35/74
Filed: 1992-01-28
Granted: 2002-05-23
Abstract: A method of establishing direct feed microorganisms such as Lactobacillus reuteri in the gastrointestinal tract of avian organisms in which eggs are inoculated with living cells of the microorganism.
Patent DE-69300857-D1 (DE)
Inventor: KIM CHOUNG UN
IPC: A61K31/505
Filed: 1993-08-31
Granted: 1996-01-04
Abstract: Thymidine kinase inhibitor of formula I <CHEM> in which R is C1-6 alkyl or Ar(CH2)n-, wherein Ar represents phenyl optionally substituted with one to five same or different halogen, C1-6 alkyl or C1-6 alkyloxy; and n equals one to six. A further aspect of the present invention is the use of such thymidine kinase inhibitor in the manufacture of a composition to inhibit viral thymidine kinase. Yet another aspect of the invention relates to the use of such a thymidine kinase inhibitor in the manufacture of a medicament for treating herpes simplex viral infection in mammals. Yet another aspect of the invention provides a pharmaceutical formulation.
Patent DE-69308649-D1 (DE)
Inventor: MOOIWEER HENDRIK HARM
IPC: B01J29/70
Filed: 1993-06-11
Granted: 1997-04-17
Abstract: Process for the conversion of a feedstock comprising linear olefins into a product enriched in branched olefins, which process comprises contacting the feedstock with a tectometallosilicate having a ferrierite crystal structure at an olefin partial pressure of less than or equal to 0.5 bar.
Patent DE-69323589-D1 (DE)
Inventor: NISHIMURA SHINJI
IPC: C07K17/08
Filed: 1993-11-03
Granted: 1999-04-01
Abstract: The monoclonal antibodies of the present invention makes it possible to separate basophils suitable for the IgE-mediated specific chemical mediator release test, because it retains its reactivity with basophils even after being immobilized onto a solid carrier, and because it does not inhibit release of chemical mediators induced by allergens or anti-IgE antibody, and does not induce nonspecific release of chemical mediators. Also, the method for separating basophils of the present invention simplifies the separation of basophils from blood, and by using this method, the histamine release test which otherwise requires complex procedures can be simplified. Further, the group of cells obtained by the method for separating basophils of the present invention can easily be utilized in the release tests for chemical mediators released from basophils such as leukotriene and PAF, which otherwise require expertise for handling.
Patent DE-69325286-D1 (DE)
Inventor: MATKOVICH VLADO
IPC: F16L37/098
Filed: 1993-10-01
Granted: 1999-07-15
Abstract: A connector assembly includes first and second fittings (100, 200) and first and second membrane assemblies (170, 270). Each fitting (100, 200) defines a respective aperture (141, 231). Each membrane assembly has a layer (172a, 272a) sealing the aperture and a removable contamination containment layer (182a, 282a) overlying a respective sealing layer. The first and second fittings (100, 200) may be resiliently coupled in biased opposition to urge positive contact between the first and second removable contamination containment layers (182a, 282a) and/or the first and second sealing layers (172a, 272a). In one application, a connector assembly according to the invention may define a fluid communication path for handling a fluid without allowing the level of contaminants in the fluid to increase. A connector assembly according to the invention may be used to handle a biological fluid while maintaining the fluid free of viable contaminating microorganisms or preserving its sterility, for example.
Patent DE-69416599-D1 (DE)
Inventor: RUBBIA CARLO
IPC: G21D1/00
Filed: 1994-07-25
Granted: 1999-03-25
Abstract: PCT No. PCT/EP94/02467 Sec. 371 Date Apr. 24, 1996 Sec. 102(e) Date Apr. 24, 1996 PCT Filed Jul. 25, 1994 PCT Pub. No. WO95/12203 PCT Pub. Date May 4, 1995A method for producing energy from a nuclear fuel material contained in an enclosure, through a process of breeding of a fissile element from a fertile element of the fuel material via a  beta -precursor of the fissile element and fission of the fissile element. A high energy particle beam is directed into the enclosure for interacting with heavy nuclei contained in the enclosure so as to produce high energy spallation neutrons. The neutrons thereby produced are multiplied in steady sub-critical conditions by the breeding and fission process. The breeding and fission process is carried out inside the enclosure.
Patent DE-69421683-D1 (DE)
Inventor: MELLEM JOACHIM
IPC: C03B37/01
Filed: 1994-08-23
Granted: 1999-12-23
Abstract: PCT No. PCT/EP94/02786 Sec. 371 Date Oct. 24, 1995 Sec. 102(e) Date Oct. 24, 1995 PCT Filed Aug. 23, 1994 PCT Pub. No. WO95/07242 PCT Pub. Date Mar. 16, 1995An apparatus for defibrating optically dense glass melts, such as a glass melt from basalt by the jet process, is proposed which is equipped with a feeding mechanism (1) for the melt and defibrating aggregates (2), the feeding mechanism (1) having a feed channel (3) and a subsequent distributing channel (4) with outlet ports (5) to the defibrating aggregates (2). To homogenize the glass temperature in the area before the defibrating aggregates (2) the feed channel (3) has on the bottom side at least in the area adjacent the distributing channel (4) a warming device (8) serving as a thermal barrier or active insulation and advantageously formed as an electric resistance heating device.
Patent DE-69423368-D1 (DE)
Inventor: ASPLUND JOHAN
IPC: G06Q20/36
Filed: 1994-12-08
Granted: 2000-04-13
Abstract: PCT No. PCT/SE94/01180 Sec. 371 Date Jul. 8, 1996 Sec. 102(e) Date Jul. 8, 1996 PCT Filed Dec. 8, 1994 PCT Pub. No. WO95/16245 PCT Pub. Date Jun. 15, 1995A travel registration arrangement including a travel pass unit for general communication, e.g. by train, by air, by sea, by bus. The unit (15) includes a processor, a write and erasable memory unit connected to the processor, a display window (2) and keys that can be manipulated by a traveller provided with the travel pass. The system includes a station (10) for issuing the travel pass unit. A traveller who wishes to obtain a travel pass is registered in the station together with a code number which is unique to the unit (15) and which is written into a fixed memory. Data relating to the traveller is written into the writable memory unit of the travel pass and, on the occasion of issue, possibly also data relating to the journey or route concerned. Data relating to the issued travel pass is stored in a data base (11), together with information relating to the journey or route concerned. A plurality of terminals (17-20) which include travel pass unit readers/writers are connected to the data base (11). Subsequent to inserting the travel pass unit, each terminal will scan the data written in its memory, check this data with data in the date base relating to the travel pass unit, and check that the data contained in the travel pass unit relating to journey or route coincides with the journey or route written in the data base. If no agreement is found, the data stored in the data base relating to the journey or the route is written into the memory of the travel pass unit.
Patent DE-69430986-D1 (DE)
Inventor: SAXE ROBERT L
IPC: G02F1/17
Filed: 1994-04-28
Granted: 2002-08-22
Abstract: A light valve has opposed, spaced apart cell walls, each cell wall carrying an electrode thereon for application of an electrical field to the light valve, at least one of the electrodes comprising a low-emissivity, electrically conductive material.
Patent DE-69433399-D1 (DE)
Inventor: SPRIGGS K
IPC: A61K35/12
Filed: 1994-01-21
Granted: 2004-01-22
Abstract: CD4+ cells obtained from individuals with defective CD40L gene and transfected with a vector containing CD40-L are described.
Patent DE-69516100-D1 (DE)
Inventor: RAULT SYLVAIN
IPC: C07D495/14
Filed: 1995-12-19
Granted: 2000-05-11
Abstract: Ethers of tricyclic oximes of formula (I), their cis and trans isomers, enantiomers and diastereomers, and their hydrates and/or acid or base addn. salts, are new. R1 = H, alkyl, alkenyl, cycloalkyl, cycloalkyl(1-4C)alkyl, hydroxy, alkoxy, opt. substd. phenyl, opt. substd. phenyl(1-4C)alkyl, opt. substd. phenoxy, or opt. substd. phenyl(1-4C)alkoxy; or R1+R2 form a chain (i) such that a 5-8 atom ring is formed; R2, R3 = H, alkyl, alkenyl, cycloalkyl, opt. substd. indanyl, cycloalkyl(1-4C)alkyl, opt. substd. phenyl, or opt. substd. phenyl(1-4C)alkyl; or NR2R3 = a heterocyclic gp. (ii) or (iii); m = 0-4; n = 0, 1 or 2; Y' = O, S or N-R4; R4 = H, alkyl or opt. substd. (CH2)qphenyl; q, x, y = 0-4; A = a gp. (a), (b) or (c); R5, R6 = H, OH, alkyl, alkoxy, halo, CF3, alkoxycarbonyl, opt. substd. (CH2)p-phenyl or opt. substd. O-(CH2)p'-phenyl; p, p' = 0-4; unless otherwise stated, alkyl, alkoxy = 1-6C; alkenyl = 2-6C; cycloalkyl = 3-8C; opt. substd. = opt. substd. on phenyl by one or more alkyl, alkoxy, OH, halo, CF3, nitrile or nitro.
Patent DE-69520360-D1 (DE)
Inventor: SOHDA TAKASHI
IPC: C07F9/6561
Filed: 1995-07-03
Granted: 2001-04-19
Abstract: PCT No. PCT/JP95/01328 Sec. 371 Date Aug. 11, 1995 Sec. 102(e) Date Aug. 11, 1995 PCT Filed Jul. 3, 1995 PCT Pub. No. WO96/01267 PCT Pub. Date Jan. 18, 1996The present invention relates to a compound of the general formula (I):    <IMAGE>  (I)  wherein ring A is a benzene ring that may be substituted; Y is a divalent group as a constituent member of ring B forming a 5- to 8-membered ring; Q1 is a group of the formula -X-P(O)(OR1)(OR2) wherein X is a bond or a divalent group; R1 and R2, identical or different, are hydrogen or a lower alkyl, or may be combined together to form a ring; Q2 is hydrogen, a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; and the group of the formula -CON(Q1)(Q2) is connected to the a- or b-position carbon atom, or a salt thereof, which is useful as prophylactic and therapeutic agents of various metabolic bone diseases such as osteoporosis.
Patent DE-69530511-D1 (DE)
Inventor: GRAHAM DANIEL
IPC: A61K31/4427
Filed: 1995-11-27
Granted: 2003-05-28
Abstract: PCT No. PCT/SE95/01416 Sec. 371 Date Dec. 18, 1995 Sec. 102(e) Date Dec. 18, 1995 PCT Filed Nov. 27, 1995A compound of formula (II), either as a single enantiomer or in an enantiomerically enriched form    <IMAGE>  (II)  wherein:   <IMAGE>   and   <IMAGE>    <IMAGE>   (wherein N in the benzimidazole moiety of Het2 means that one of the carbon atoms substituted by any one of R6 to R9 optionally may be exchanged for an unsubstituted nitrogen atom; R1, R2 and R3 are the same or different and selected from hydrogen, alkyl, alkoxy optionally substituted by fluorine, alkylthio, alkoxyalkoxy, dialkylamino, piperidino, morpholino, halogen, phenylalkyl, phenylakoxy; R4 and R4, are the same or different and selected from hydrogen, alkyl, aralkyl; R5 is hydrogen, halogen, trifluoromethyl, alkyl, alkoxy; R6 -R9 are the same or different and selected from hydrogen, alkyl, alkoxy, halogen, haloalkoxy, alkylcarbonyl, alkoxycarbonyl, oxazolyl, trifluoroalkyl or adjacent groups R6 -R9 may complete together with the carbon atoms to which they are attached optionally substituted ring structures; R10 is hydrogen or alkoxycarbonyloxymethyl; R11 is hydrogen or forms an alkylene chain together with R3; R12 and R13 are the same or different and selected from hydrogen, halogen or alkyl) is obtained by stereoselective bioreduction of a compound of formula (II) in racemic form.
Patent DE-69600227-D1 (DE)
Inventor: JUNG CHRISTOPHER C
IPC: A61F9/007
Filed: 1996-09-30
Granted: 1998-05-14
Abstract: A process control system (1) according to the present invention uses analog control circuitry in which a differential amplifier stage (54) is incorporated into the feedback path rather than the feedforward path to enable the control of highly non-linear processes that may also exhibit high levels of hysteresis. Such processes often have superior performance characteristics that conventional control circuitry cannot exploit. The present invention additionally incorporates an automatic control circuit which varies the gain of various stages of the control circuitry when the output of the process is within a predetermined range. An embodiment of the present invention is used to control a non-linear proportional valve (18) with severe hysteresis. The valve regulates the pressure within pressure-driven ophthalmic surgical instruments (42) which must be controlled extremely precisely to enable successful eye surgery. <IMAGE>
Patent DE-69617951-D1 (DE)
Inventor: SRIVASTAVA P
IPC: C07H15/18
Filed: 1996-06-06
Granted: 2002-01-24
Abstract: The present invention is directed to methods of reducing the degree of inflammation arising from a secondary immune response in a mammal due to antigen exposure (challenge) by the administration of valienamine-related disaccharide compounds and the pharmaceutical compositions employed in the method.
Patent DE-69618676-D1 (DE)
Inventor: JAQUET ARNOLD
IPC: B65G47/26
Filed: 1996-10-28
Granted: 2002-02-28
Abstract: An apparatus for temporarily storing or buffering and/or setting the pitch of products, comprised of a conveyor belt, a product carrier for transporting by the conveyor belt and for carrying a plurality of products, a feed conveyor for feeding products into the product carrier at a first predetermined location of the conveyor belt, and a discharge element such as a robot, top loader or pushing member for discharging the products from the product carrier at a second predetermined location a distance from the first predetermined location.
Patent DE-69620488-D1 (DE)
Inventor: COPE CARROLL W
IPC: B29C48/00
Filed: 1996-01-26
Granted: 2002-05-16
Abstract: A solid, elongated member of predetermined profile having a solid skin (90, 92, 94) on a portion of its surface and a decorative enhancement (86, 88) integrally formed on another portion is formed by compressing extrudable foam material by passing it through an orifice having a predetermined profile at one end, hardening a first portion of its surface during compression to form the solid skin, and embossing a second portion of its surface following compression by moving a heated embossing wheel over its profile to provide the decorative enhancement before hardening the material.
Patent DE-69630772-D1 (DE)
Inventor: CAMPS GARCIA PELAYO
IPC: A61P25/28
Filed: 1996-10-11
Granted: 2003-12-24
Abstract: New polycyclic aminopyridine compounds which are acetylcholinesterase inhibitors, process for preparing them and their use. The polycyclic aminopyridine compounds correspond to the formula <CHEM> in which the various radicals have the meanings stated in the specification. The process for preparing these compounds is characterized in that ketones of general formula (II) are reacted with aminonitriles of general formula (III) and, if necessary, the compounds of formula (I) are alkylated, aralkylated or acylated, or alternatively the corresponding keto precursor is reduced. The compounds of the general formula (I) are especially suitable for the preparation of medicaments against memory disorders such as senile dementia or Alzheimer's disease.
Patent DE-69631331-D1 (DE)
Inventor: ARMITAGE J
IPC: C07K14/725
Filed: 1996-06-06
Granted: 2004-02-19
Abstract: There is disclosed a polypeptide that is mutein of CD40L, and DNA sequences, vectors and transformed host cells useful in providing such CD40L muteins.
Patent DE-69633121-D1 (DE)
Inventor: DAVIS SAMUEL
IPC: C12N5/10
Filed: 1996-04-05
Granted: 2004-09-16
Abstract: The present invention provides for an isolated nucleic acid molecule encoding a human TIE-2 ligand. In addition, the invention provides for a receptorbody which specifically binds a human TIE-2 ligand. The invention also provides an antibody which specifically binds a human TIE-2 ligand. The invention further provides for an antagonist of human TIE-2. The invention further provides for a ligandbody which specifically binds TIE-2 receptor. The invention also provides for therapeutic compositions as well as a method of blocking blood vessel growth, a method of promoting neovascularization, a method of promoting the growth, differentiation or migration of cells expressing the TIE-2 receptor, including, but not limited to, hematopoietic precursor cells, a method of blocking the growth, differentiation or migration of cells expressing the TIE-2 receptor including, but not limited to, hematopoietic precursor cells, and a method of attenuating or preventing tumor growth in a human.
Patent DE-69709070-D1 (DE)
Inventor: HORWELL CHRISTOPHER
IPC: A61P25/28
Filed: 1997-02-18
Granted: 2002-01-24
Abstract: PCT No. PCT/US97/02401 Sec. 371 Date May 19, 1998 Sec. 102(e) Date May 19, 1998 PCT Filed Feb. 18, 1997 PCT Pub. No. WO97/33859 PCT Pub. Date Sep. 18, 1997Bridged cyclic amino acids of formula are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed.
Patent DE-69710182-D1 (DE)
Inventor: SPINELLI SILVANO
IPC: A61K31/00
Filed: 1997-03-27
Granted: 2002-03-14
Abstract: PCT No. PCT/EP97/01582 Sec. 371 Date Nov. 12, 1998 Sec. 102(e) Date Nov. 12, 1998 PCT Filed Mar. 27, 1997 PCT Pub. No. WO97/37658 PCT Pub. Date Oct. 16, 1997The present invention concerns the use of beta-carboline derivatives of formula I bearing at least a free or esterified carboxylic group on the piperidine ring, for the preparation of pharmaceutical compositions having antimetastatic properties.
Patent DE-69715643-D1 (DE)
Inventor: NIELSEN MANN
IPC: C09J123/22
Filed: 1997-07-02
Granted: 2002-10-24
Abstract: An adhesive agent for application to human or animal skin, preferably for use in connection with ostomy or incontinence appliances, comprises a pressure sensitive adhesive and optionally additives conventionally used in adhesives of this kind and parts of or extracts from Aloe vera. Such adhesive prevents or alleviates skin problems.
Patent DE-69802672-D1 (DE)
Inventor: VILJANMAA MIKA
IPC: D21G1/02
Filed: 1998-03-26
Granted: 2002-01-10
Abstract: A calendering method and calender in which a web material is passed through a calender, the calender being defined by two rolls having resilient roll coatings and being loaded towards each other so that due to the resilient nature of the roll coatings an extended nip is defined. Each of the calendering rolls being covered by a flexible calendering belt that is non-compressible in comparison to the roll coatings and each of the calendering belts being formed into a endless loop by passing over a respective alignment or reversing roll.
Patent DE-69808013-D1 (DE)
Inventor: SICILIA ROBERT DOMENIC
IPC: B29C45/16
Filed: 1998-10-08
Granted: 2002-10-24
Abstract: A method and apparatus for runnerless injection molding of plastic materials utilizing a novel valve stem (83) for controlling the opening and closing of at least two gates (76a,76b) in a single injection nozzle (64) . The method and apparatus includes at least two separate melt streams (63,67) whose flows are not obstructed by the valve stem (83). These melt streams may contain the same plastic material or different plastic materials and the injection nozzle may either simultaneously or sequentially activated for filling the mold cavity. <IMAGE>
Patent DE-69817617-D1 (DE)
Inventor: REAY GAVIN
IPC: G06F3/038
Filed: 1998-12-21
Granted: 2003-10-02
Abstract: A two-axis angle sensor comprising a pair of bubble chambers (3,4) and associated bubble detectors (5,6). A processor (42) calculates the angle of the sensor by combining the signals from the first and second bubble detectors in accordance with a predetermined algorithm. A radiation source (1) illuminates a bubble (8) with radiation whereby the radiation is refracted by the bubble. A radiation detector (5,6) is positioned to detect the refracted radiation from the bubble and generate a signal indicative of the angle of the bubble chamber. An angle sensor is used to calibrate a vibrating structure gyroscope (70). A flywheel (91) is provided to generate a gyroscopic resistance to operator input. A method of manufacturing a bubble angle sensor is disclosed, the method employing a lid (61) with an internal recess (65).