baber/WOPTO huggingface dataset:
Patent NZ-511584-A (NZ)
Title: Benzoxazole substituted piperazine and piperidine derivatives useful for treating central nervous disorders, depression and anxiety
Inventor: VAN SCHARRENBURG GUSTAAF J M
IPC: A61P25/24
Filed: 1999-11-10
Abstract: Piperazine and piperidine derivatives of formula (I), their salts and pharmaceutical compositions, where: S1 is hydrogen, halogen, alkyl (1-3C), CN, CF3, OCF3, SCF3, alkoxy (1-3C), amino or mono- or dialkyl (1-3C) substituted amino, or hydroxy; X represents NR3, S, CH2, O, SO or SO2, where R3 is H or alkyl (1-3C);. Z represents =C or -N; R1 and R2 independently represent H or alkyl (1-3C), or R1 and R2 together can form a bridge of 2 or 3 C-atoms; R4 is hydrogen or alkyl (1-3C); Q is methyl, ethyl, ethyl substituted with one or more fluorine atoms, cyclopropyl - methyl, optionally substituted with one or more fluorine atoms. These compounds have both partial dopamine D2-receptor agonism and partial serotonin 5-HT1A-receptor agonism mediated activities.
Patent NZ-512484-A (NZ)
Title: Regulating lipid concentration in mammals by administering an acyl-CoA cholesterol O-acyltransferase (ACAT) inhibitor and an HMG-CoA reductase inhibitor
Inventor: BOCAN THOMAS M A
IPC: A61K31/22
Filed: 1996-10-02
Abstract: Described is a pharmaceutical composition for regulating lipid concentration in a mammal comprising a therapeutically effective amount of an acyl-CoA cholesterol O-acyltransferase (ACAT) inhibitor, for example, sulfamic acid, [[2,4,6,-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester, and an HMG-CoA-reductase inhibitor, for example, atorvastatin.  The combination of agents results in a greater reduction in plasma VLDL and LDL cholesterol and increases HDL cholesterol than either agent alone resulting in a less atherogenic lipoprotein profile.  The combination is useful in the treatment of patients with or at risk of developing ischemic syndromes in order to restore endogenous vascular endothelium-dependent activities.
Patent NZ-512879-A (NZ)
Title: Modulation of immune response by Ribavirin
Inventor: TAM ROBERT
IPC: A61K31/70
Filed: 1999-12-20
Abstract: The response of an immune system to a challenge is modified by presenting the system with a nucleoside in a concentration selected to have an effect on a B7 marker that is inverse from the effect of the challenge.  Contemplated challenges include allergens, neoplasm, virus, bacteria, infestation, and autoimmune reaction.  Molecular markers of particular interest are B7-1 and B7-2.  Preferred nucleosides are Ribavirin and Ribavirin analogues, especially provided within a concentration range between about 0.2M and about 5M, respectively, in a fluid containing cells expressing the B7 marker.
Patent NZ-516767-A (NZ)
Title: Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
Inventor: MILLER MATTHEW S
IPC: A61K47/36
Filed: 2000-08-16
Abstract: The use of a modafinil compound in the preparation of a medicament for the treatment of attention deficit hyperactivity disorder in a subject suffering from or susceptible to the development of such disorder or for the treatment of multiple sclerosis fatigue in a subject suffering from such disorder.
Patent NZ-520155-A (NZ)
Title: Thienopyridine derivatives, their production and use
Inventor: YASUMA TSUNEO
IPC: A61K31/5375
Filed: 2001-02-28
Abstract: The present invention provides thienopyridine derivatives, which are useful as anti-inflammatory drugs, particularly as remedies for arthritis; processes for producing them, and pharmaceutical compositions containing them. The thienopyridine derivatives are represented by the formula (I), wherein; G is a halogen atom, hydroxyl group, an optionally substituted amino, alkyl, alkoxy group; alk is an optionally substituted lower alkylene group;  X is O, S, -(CH2)q; R is an optionally substituted amino or heterocyclic group; Ring B is an optionally substituted Y-containing 5- to 8-membered ring whose ring constituent atoms contain no nitrogen atom; Y is O, S, or one of the groups described in the specification; and ring A is an optionally substituted benzene ring or salt thereof.
Patent NZ-536553-A (NZ)
Title: Animal model for toxicology and dose prediction
Inventor: MATHER JENNIE P
IPC: C12N5/074
Filed: 2003-05-30
Abstract: Provided is a method for generating a non-human vertebrate animal model having both normal tissue of mature phenotype and diseased tissue, both from a donor animal, comprising: (a) implanting immature normal tissue in or under a kidney capsule; (b) allowing the normal tissue to develop into a mature tissue; (c) implanting diseased tissue in or under the contralateral kidney capsule; and (d) allowing the diseased tissue to grow. Also provided is a similar method using two different locations of a fat pad or different fat pads as locations of the two implanted tissues. Further provided is a corresponding tissue model for tissues implanted in a kidney capsule or in a fat pad and a rodent having the tissue models. Also provided are methods for assessing the effect of therapeutic treatments and screening and testing of treatments using the tissue models and animals having the tissue models. Further provided are methods to produce such animal models.
Patent NZ-539364-A (NZ)
Title: Anti-icing system for wind turbines
Inventor: BATTISTI LORENZO
IPC: F03D11/00
Filed: 2003-10-16
Abstract: A de-icing and anti-icing arrangement for a Wind Energy Converting System (WECS), a WECS comprising a de-icing and anti-icing arrangement and a method for preventing and eliminating ice accretion on the rotor blades of a WECS are provided. The WECS comprises a tower, a rotor having a plurality of blades that rotate due to wind force, a nacelle including a first means for transforming the rotor's rotational movement to electric power, and a second means for permitting the flow of fluid from volumes defined by the rotor blades, the rotor blades comprising an external surface having openings in fluid connection with the volumes inside the blades for permitting the flow of fluid to the outside of the blades to fluid-thermodynamically interact with the wind hitting the part of the blade surface, and thereby prevent or eliminate the accretion of ice on the external surface of the blade.
Patent NZ-539675-A (NZ)
Title: Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer
Inventor: FRIEDMAN GLENN
IPC: A61K/
Filed: 2003-10-15
Abstract: Benzopyranone compounds of formula (I), and pharmaceutically acceptable salts thereof are disclosed, wherein R1 is halogen, trifluoromethyl or C1-6 alkyl. These benzopyranone compounds and their pharmaceutical compositions are suitable for treating or preventing cancer or inhibiting the growth of a cancer cell or neoplastic cell.
Patent NZ-543016-A (NZ)
Title: Azetidinecarboxamide derivatives and their use in the treatment of CB1 receptor mediated disorders
Inventor: DAVIDSON JAMES EDWARD PAUL
IPC: A61P3/04
Filed: 2004-04-29
Abstract: Disclosed is the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment of psychosis, memory deficit, attention deficit disorder, migraine, neuropathy, neuro-inflammatory disorders, cerebral vascular injuries, head trauma, depression, stress, Huntingdon's disease, Tourette's syndrome, ischaemia, Parkinson's disease, schizophrenia, smoking cessation, treatment of nicotine dependence and/or treatment of symptoms of nicotine withdrawal, gastrointestinal disorders, eating disorders associated with excessive food intake, and non-insulin dependant diabetes mellitus, wherein R1 and R2 are independently selected from substituted or unsubstituted aryl; and R3 is hydrogen or substituted or unsubstituted alkyl; wherein at least one of R1 and R2 has a non-hydrogen substituent in the ortho-position(s) thereof relative to the point of attachment to the [-CH-O-] group.
Patent NZ-544848-A (NZ)
Title: High frequency circuit analyser
Inventor: BENEDIKT JOHANNES
IPC: G01R27/32
Filed: 2004-07-23
Abstract: An analyser for measuring the response of an electronic device (206 ) to a high frequency input signal (240a) is disclosed. The analyser includes an active load pull circuit (201) which is connectable in use to a device (206) to be analysed. The active load pull circuit (201) includes: a feedback circuit (236) arranged (i) to receive an output signal from the device (206) to be analysed, (ii) to modify the signal, where the modification includes limiting the magnitude gain of the feedback circuit at frequencies outside a band of frequencies, (iii) to feed the modified signal back to the device (206) to be analysed, where the modified signal fed back includes a component having a frequency within the band, characterised in that the feedback circuit is also arranged to limit the magnitude gain of the feedback circuit at frequencies inside the band of frequencies.
Patent NZ-551839-A (NZ)
Title: Stable crystal of 4-oxoquinoline compound
Inventor: SATOH MOTOHIDE
IPC: A61P31/18
Filed: 2005-05-19
Abstract: The disclosure relates to polymorphic crystalline forms of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, which shows a particular powder X-ray diffraction pattern of a characteristic diffraction peaks at diffraction angles 2theta ( DEG ) as measured by powder X-ray diffractometry. These crystals are superior in physical and chemical stability and are suitable as anti-HIV agents, HIV integrase inhibitors, antivirus agents and may be used for the prophylaxis and treatment of AIDS.
Patent NZ-553831-A (NZ)
Title: Inositol polyphosphate 2-kinase genes and uses thereof
Inventor: THOMPSON MARK ALLEN
IPC: A01H5/00
Filed: 2005-09-09
Abstract: Disclosed is a polynucleotide coding for an isolated polyphosphate 2 kinase, the polynucleotide comprising a member selected from the group consisting of: (a) a polynucleotide comprising SEQ ID NO: 1 (b) a polynucleotide comprising at least 99% identity to SEQ ID NO: 1 (c) a polynucleotide encoding a polypeptide comprising SEQ ID NO: 2. Further disclosed are polypeptides encoded by said polynucleotide, methods of identifying plant tissue comprising a lesion in said polypeptides, corn and canola seed comprising a gene encoding said polypeptide, vectors comprising said polynucleotide for transformation of plant cells, antisense nucleotide comprising said polynucleotide, plants and progeny transformed with said vectors and other methods and uses thereof comprising said polynucleotide or polypeptide.
Patent NZ-560960-A (NZ)
Title: Near reverse breeding
Inventor: VAN DUN CORNELLS MARIA PETRUS
IPC: C12N15/82
Filed: 2006-03-02
Abstract: Disclosed is a method for producing a homozygous organism selected from plant, fungi or fish from a heterozygous organism, which homozygous organism can be crossed to obtain a hybrid, comprising: a) providing a heterozygous starting organism; b) allowing the organism to produce SDR-O cells originating from second division restitution; c) regenerating SDR-O organisms from the SDR-O cells; and d) producing the homozygous organism from the SDR-O organisms thus obtained.
Patent NZ-571432-A (NZ)
Title: Method and plant for integrated monitoring and control of strip flatness and strip profile
Inventor: MUELLER JASON A
IPC: B21B37/16
Filed: 2007-03-07
Abstract: Disclosed is an apparatus and method of controlling strip geometry in a casting plant having a rolling mill. A target thickness profile is calculated as a function of the measured entry thickness profile of the strip while satisfying profile and flatness operating requirements. A differential strain feedback from longitudinal strain in the strip is calculated by a control system by comparing the exit thickness profile with the target thickness profile, and a control signal is generated to control a device capable of affecting the geometry of the strip processed by the hot rolling mill. A feed-forward control reference and/or sensitivity vector may also be calculated as a function of the target thickness profile, and used in generating the control signal sent to the control device. The control device may be selected from one or more of the group consisting of a bending controller, gap controller and coolant controller.
Patent NZ-572884-A (NZ)
Title: Transformation of eukaryotic cells using two different recombination sites recognised by two different unidirectional site-specific recombinases
Inventor: RUTTER WILLIAM J
IPC: C12N15/85
Filed: 2007-05-22
Abstract: A site-specifically integrating target vector that comprises: (a) A first vector recombination site that recombines with a genomic recombination site in the presence of a first unidirectional site-specific recombinase; (b) A second vector recombination site that recombines with donor recombination site in the presence of a second unidirectional site-specific recombinase that is different from the first unidirectional site-specific recombinase; (c) A promoter-less first portion of first selectable marker adjacent to the second vector site's 3' end; and (d) A second selectable marker that is different from the first selectable marker. The vector is used in conjunction with a donor vector that comprises a polynucleotide encoding a protein of interest, a donor recombination site and a second portion of a first selectable marker which comprises a promoter. The vector is used in methods for integrating a protein of interest into the genome of a eukaryotic cell for protein production.
Patent NZ-576522-A (NZ)
Title: Putting an absorbent material and liquid settable material into cable gland
Inventor: PRATLEY KIMLEIGH GEORGE MONTAGUE
IPC: H02G3/18
Filed: 2007-11-15
Abstract: A method of forming a seal 62 between and around conductors 12A, 12B and 12C of an electrical power cable 10 that has particular application as a safety measure in potentially explosive applications, includes passing the conductors 12A, 12B and 12C through an opening in a body 26 such as a cable entry gland so as to define a cavity within the body between and around the conductors, introducing an absorbent material 64 and a liquid settable material 66 into the cavity, and allowing the settable material 66 to be absorbed by the absorbent material 64 and to set thereby to seal the cavity between and around the conductors. The absorbent material may be in the form of powder, granules or fibres and the settable material may be an acrylic or epoxy resin with a reaction catalysed by the absorbent material and which fuses, during setting, with the insulation of the cable conductors.
Patent NZ-579570-A (NZ)
Title: Method of treating or preventing tissue deterioration, injury or damage due to disease of mucosa
Inventor: RIOS ISRAEL
IPC: A61K38/00
Filed: 2008-02-11
Abstract: Disclosed herein is the use of an effective amount of ã-D-glutamyl-L-tryptophan (also referred to as SCV-07) or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for reducing the amount of mucosal deterioration, injury or damage to at least one of oral and esophageal mucosal tissues, the mucosal deterioration, injury or damage resulting from radiation therapy for head and neck cancer.
Patent NZ-579757-A (NZ)
Title: A single step process for separating biomass components
Inventor: SRIVASTAVA SURESH CHANDRA
IPC: C12P7/10
Filed: 2008-06-19
Abstract: Disclosed is a process for obtaining cellulose from biomass in a form amenable to complete enzymatic hydrolysis, said process comprising contacting the biomass with a mixture of an organic solvent immiscible in water selected from a group comprising butanol and iso-amyl alcohol, a mineral acid (such as sulphuric acid) and a metal salt catalyst selected from copper sulphate, ferrous sulphate, ferrous ammonium sulphate, nickel sulphate, sodium sulphate, ferric chloride dissolved in an aqueous solution under a temperature in the range of 120° - 220°C and pressure in the range of 1.5 - 20 bar and filtering the reaction mixture under pressure to separate the dissolved lignin, hemicellulose in the solvent and aqueous phase respectively and leaving behind pure cellulose.
Patent NZ-581041-A (NZ)
Title: Screw pile with band affixed to upper screw portion to resist lateral forces
Inventor: COATS DANIEL HYLTON
IPC: E02D5/56
Filed: 2009-11-10
Abstract: An upper portion of a screw pile has a band secured to an upper helical blade portion with the band running parallel to pile axis so as to provide a degree of resistance against lateral forces.
Patent NZ-581507-A (NZ)
Title: Monoclonal antibodies expressed by ATCC PTA-4621 for the treatment of cancer
Inventor: YOUNG DAVID S
IPC: C07K16/28
Filed: 2008-05-23
Abstract: Disclosed is a humanized antibody comprising: a heavy chain variable region comprising the complementarity determining region amino acid sequences of SEQ ID NO:1, SEQ ID NO:2, and SEQ ID NO:3; and a light chain variable region comprising the complementarity determining region amino acid sequences of SEQ ID NO:4, SEQ ID NO:5, or SEQ ID NO:6; or a human CD44 binding fragment thereof; wherein said humanized antibody specifically binds the same epitope or epitopes of human CD44 as the isolated monoclonal antibody produced by the hybridoma cell line H460-16-2 having ATCC Accession No. PTA-4621. Also disclosed is the use of the antibody or human CD44 binding fragment thereof for the preparation of a medicament for treating a human breast or prostate tumor.
Patent NZ-584347-A (NZ)
Title: Methods of placing concrete
Inventor: WOOLFSMITH DANIEL
IPC: C04B16/08
Filed: 2008-09-18
Abstract: Disclosed is a method of placing a light weighted concrete compositions comprising: a) combining ingredients comprising 3 -40 volume percent cement, 5 - 50 volume percent fine aggregate, 1.5 - 50 volume percent coarse aggregate, and 10 - 22 volume percent water to form a concrete mixture; during or after (a), adding 5 - 40 volume percent of prepuff particles to the concrete mixture to form a light weighted concrete composition; and pumping the light weighted concrete composition to a point higher in elevation than the delivery point of the concrete to place the concrete; wherein the light weighted concrete composition contains less than 30 volume percent of other light weighting aggregates; wherein the prepuff particles have an average particle diameter of from 0.2 mm to 8 mm, a bulk density of from 0.02 g/cc to 0.64 g/cc, an aspect ratio of from 1 to 3; wherein the slump value of the placed light weighted concrete composition measured according to ASTMC 143 is greater than 1 inch; and wherein the light weighted concrete composition has a density of from about 40 to about 135 lb./lft cubed. Also disclosed is a concrete slab made according to said method.
Patent NZ-590065-A (NZ)
Title: Method for assembling submarine power station which has a nacelle
Inventor: HOLSTEIN BENJAMIN
IPC: F03B13/10
Filed: 2009-07-03
Abstract: Disclosed is a submarine power station for generating power from a water current. The power station comprises a machine gondola with a gondola housing (4) around which the water current flows. The gondola housing has a first gondola housing section (4.1) with a driveshaft (5) mounted in it, and the water flow droves a water turbine (3) which is in drive connection with the driveshaft. The housing further contains an electrical generator (6) with a generator rotor (7), a generator stator (8) and a generator housing (9). The invention is characterised in that the electrical generator and the generator housing form a separate generator module (10), which can be manoeuvred and assembled in one piece and connector means are provided to couple the generator housing to the first gondola housing section and to couple the generator rotor in a rotationally fixed manner to the drive shaft.
Patent NZ-590086-A (NZ)
Title: Pressure vessel for compressed gas with a computer, a display, and sensors to measure temperature and pressure and indicate amount of gas remaining
Inventor: LIEBENBERG ADRIENNE
IPC: F17C13/02
Filed: 2010-12-21
Abstract: The pressure vessel for containing compressed gas has a shut-off valve in engagement with the mouth of the pressure vessel, and a pressure sensor in continuous contact with the interior of the pressure vessel, and a temperature sensor for sensing the gas temperature in the vessel. The vessel also has a programmable computer device with a display screen for calculating information on the amount of contents based on signals from the pressure and temperature sensors.
Patent NZ-590649-A (NZ)
Title: Edible olive pomace oil concentrated in triterpenic acids, procedure of physical refining utilised for obtainment thereof and recovery of functional components present in the crude oil
Inventor: SANCHEZ MORAL PEDRO
IPC: A23D9/00
Filed: 2009-07-21
Abstract: Disclosed herein is a refining process of crude olive pomace oil obtained by centrifugation or decantation of the pomace characterized in that it includes the following steps: a) filtration of the starting crude olive pomace oil carried out through filters having a pore size included in the interval of 0.1 to 20 microns and a temperature below 70 ºC, preferably between 35-45 ºC b) bleaching of the oil filtered in the previous step at a temperature included in the interval between 80 ºC and 120 ºC, at a pressure below 70 mbar, preferably 40 mbar, and the following steps: i. addition of technological coadjuvants selected from activated bleaching earth, amorphous silica or active carbon, ii. stirring of the mixture of the oil with the technological coadjuvants, preferably for a maximum of 30 minutes and, iii. filtration to remove the coadjuvants added c) distillation of the bleached oil obtained in the previous step.
Patent NZ-591018-A (NZ)
Title: Mask system for CPAP using nasal prongs having self adjustable properties in use
Inventor: LUBKE STEVEN JOHN
IPC: A61M16/06
Filed: 2006-06-06
Abstract: 591018 Disclosed is a CPAP or continuous positive air pressure mask system for use between a patient and a device to deliver a breathable gas to the patient. The mask system comprises a mouth cushion formed of silicone and structured to sealingly engage around an exterior of a patient's mouth in use and a pair of nasal prongs releasably attached to a side wall of the mouth cushion and structured to sealingly communicate with nasal passages of a patient's nose in use. An elbow delivers breathable gas to the patient at a pressure elevated above atmospheric pressure and a headgear assembly maintains the mouth cushion and the nasal prongs in a desired position on the patient's face. Each prong includes a base portion provided to the mouth cushion, a head portion to seal with the patient's nose, and a stalk to interconnect the base portion and the head portion. Each prong also includes a first flexible base provided between the head portion and the stalk and a second flexible base provided between the stalk and the base portion. The first and second flexible bases allow rotation of the stalk relative to both the head portion and the base portion in use and allow reduction in height of the head portion relative to the base portion by allowing the stalk to move axially into the base portion and the head portion in use.
Patent NZ-591914-A (NZ)
Title: Naphthylacetic acids
Inventor: CHEN LI
IPC: A61K31/185
Filed: 2009-11-09
Abstract: 591914 Disclosed is a compound of formula (I) where the substituents are as disclosed in the description. Examples of compounds of formula (I) are: [4-(4-ethanesulfonyl-phenoxy)-6-fluoro-naphthalen-2-yl]-acetic acid; [4-(4-ethanesulfonyl-phenoxy)-6-fluoro-3-methyl-naphthalen-2-yl]-acetic acid and [6-Chloro-4-( 4-methanesulfonyl-phenoxy)-3-methyl-naphthalen-2-yl]-acetic acid. Also disclosed is a pharmaceutically acceptable salt; a pharmaceutically acceptable ester and a pharmaceutical composition of the compounds. Further disclosed is the use of a compound of formula (I) in the manufacture of a medicament to the treatment or prophylaxis of asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis, allergic inflammation, and atopic dermatitis.