baber/WOPTO huggingface dataset:
Patent WO-2023081206-A1 (WO)
Title: Water treatment with photocatalytic technology
Inventor: LIU HAIZHOU
IPC: C02F1/72
Filed: 2022-11-02
Abstract: An apparatus and method to oxidize a contaminant entrained in potable water. The method can include a step of adding an amount of at least one of hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HOCl), or chloramine (NH 2 Cl) to the potable water to form a solution. The method can include a step of exposing the solution to a source of UV radiation to form a catalyst including at least one of a hydroxyl radical, a reactive chlorine species, or a reactive amine species to oxidize the inorganic contaminant.
Patent WO-2023113955-A1 (WO)
Inventor: MUTLU WOLFGANG
IPC: B23K26/352
Filed: 2022-11-11
Abstract: A vacuum chamber for vacuum processing is provided. The vacuum chamber includes at least one device comprising at least one treated surface, the at least one treated surface being provided by ultra-short pulse laser surface treatment. The at least one treated surface is positioned and shaped so as to provide thermal energy to and/or absorb thermal energy from a component, the component being positioned in a relative position to the at least one treated surface.
Patent WO-2023102165-A1 (WO)
Inventor: KAWATRA SURENDRA KOMAR
IPC: C01B13/02
Filed: 2022-12-02
Abstract: An absorption column for the simultaneous capture of the flue gases CO 2 , NO x  and SO x , the absorption column pertaining to a single wet scrubbing absorption column at alkaline pH conditions. In some aspects, the efficacy of the single stage absorption column for the simultaneous capture of the flue gases CO 2 , NO x  and SO x  being at least 99% for CO 2 , at least 30% for NO and at least 95% for SO 2 . The single stage absorption column can have a sodium carbonate solution. The sodium carbonate solution can be enhanced by one or more oxidants as rate promoters, including H 2 O 2 , NaOCl and mixtures thereof.
Patent WO-2023107460-A1 (WO)
Inventor: CESNIK JEFFREY THOMAS
IPC: G06Q10/087
Filed: 2022-12-06
Abstract: L'invention concerne des systèmes et des procédés de surveillance à distance de liquides qui sont stockés dans des réservoirs dans une installation de stockage. Un câble rayonnant qui est en communication avec un récepteur est acheminé à travers l'installation de stockage. Des systèmes de surveillance de liquide sont associés à chaque réservoir et diffusent des signaux qui sont reçus par les câbles rayonnants. Divers aspects du liquide peuvent être surveillés, tels que le niveau de volume, la pression atmosphérique, l'humidité et la température, par l'intermédiaire de capteurs du système de surveillance de liquide.
Patent WO-2022178511-A1 (WO)
Inventor: HEIRUNG TOR AKSEL NOTLAND
IPC: G01C21/26
Filed: 2022-02-16
Abstract: A computer-implemented method comprises: detecting, by an assisted-driving system that is currently controlling motion of a first vehicle, a traffic event external to the first vehicle; and providing, by the assisted-driving system and in response to detecting the traffic event, confirmation to a passenger in the first vehicle that the assisted-driving system is handling the traffic event, the confirmation including a physical feedback perceptible to the passenger.
Patent WO-2023288290-A1 (WO)
Inventor: XIA SICHONG
IPC: B65D43/16
Filed: 2022-07-15
Abstract: A seal member is provided that may prevent fluids from leaking from a drinking bottle, such as a reusable water bottle. The seal member may be overmolded into a lid of the bottle such that the seal chemically and mechanically bonds to the lid. Overmolding the seal member eliminates gaps that could form between the seal and the lid, thus enhancing the cleanability of the seal member and the lid.
Patent WO-2023034729-A1 (WO)
Inventor: PERKINS EDWARD L
IPC: C12N9/10
Filed: 2022-08-26
Abstract: The risk with introducing manipulated T-cell is unforeseen adverse events. During the development of chimeric antigen receptor (CAR) T-cell therapies almost all clinical trial has shown some adverse events ranging from cytokine mediated toxicities to tissue damage and death. By the present invention, we aim to induce multiple layers of safety checkpoints. As a last resort we will be able to induce suicide in all cells which we have introduced to the body. Here we describe the scientific background to the parts of our suicide switch and the details regarding the proteins which are included. Safety switches are being tested on CAR-T cells, but they have a few drawbacks. Due to the limited space on the CAR vector, there is only room for one gene switch. Presently the results show they induce apoptosis in around 70-90% of cells, while the desired target is for all cells to be removed from the tissue. By utilising the space available on a synthetic chromosome, we can include multiple genes under Tet operons which allow us to turn multiple genes on/off. Life or death of a cell depends on the balance of the pro and anti-apoptotic proteins. The scale is always shifting a bit back and forth but only when tipped completely over the apoptotic cascade is initiated. By fine tuning the balance we aim to ensure that the hSync carrying cells have a survival advantage in the tumour in the absence of inducing agent. On the other hand, the moment that agent is administrated the cells will undergo apoptosis and express "find me" and "eat me" markers making sure they are removed without risk of tissue damage. The present invention encompasses compositions and methods for use in cellular gene therapeutics using a modular approach to genetically engineer cells to carry a synthetic chromosome having a regulatable system including one or more safety switches.
Patent WO-2023034993-A1 (WO)
Inventor: GLEICH GERALD
IPC: A61P29/00
Filed: 2022-09-02
Abstract: L'invention concerne des compositions et des méthodes de diagnostic, de détection et de traitement d'une maladie liée aux éosinophiles ou d'une inflammation liée aux éosinophiles chez un sujet. L'invention concerne également des compositions comprenant la pro-pièce de protéine basique majeur de granule pro-éosinophile-1 ou un fragment de celle-ci et leurs procédés d'utilisation.
Patent WO-2023049768-A1 (WO)
Inventor: JIANG PENG
IPC: C12N15/113
Filed: 2022-09-21
Abstract: In one embodiment, the invention provides a T cell exhibiting reduced or diminished FIBP or TMEM222 expression. The T cell can comprise chromosomal DNA, wherein the chromosomal DNA lacks a genetic sequence encoding an intact FIBP, TMEM222 or both FIBP and TMEM222. In another embodiment, the invention provides an extrachromosomal nucleic acid comprising a genetic sequence which is substantially complementary to a genetic sequence encoding a FIBP or TMEM222. In another embodiment, the invention provides a method for making a T cell lacking functional FIBP and/or TMEM222 expression. In another embodiment, the invention provides a composition comprising a T cell lacking functional FIBP and/or TMEM222 expression and a carrier. In another embodiment, the invention provides a method and uses involving the inventive composition for adoptive T cell transfer, such as for therapy for treating a solid tumor.
Patent WO-2023060151-A1 (WO)
Title: Peanut allergy epitope
Inventor: SPILLER BENJAMIN W
IPC: A61P37/08
Filed: 2022-10-06
Abstract: Disclosed herein is a composition comprising a mutant peanut ( Arachis hypogaea ) Ara h 6 polypeptide, a mutant Ara h 2 polypeptide, or a combination thereof in a pharmaceutically acceptable carrier, wherein the mutant Ara h 6 polypeptide and/or mutant Ara h 2 polypeptide has a reduced IgE response in a subject with a peanut allergy compared to wildtype Ara h 6 or Ara h 2 polypeptide. Also disclosed is a method for desensitizing or tolerizing a subject with a peanut allergy, comprising administering to the subject the mutant peanut Ara h 6 and/or Ara h 2 polypeptides disclosed herein. Also disclosed is a method for monitoring progress for the disclosed therapeutic methods.
Patent WO-2023092077-A1 (WO)
IPC: A63B22/04
Filed: 2022-11-18
Abstract: L'invention concerne une machine d'exercice d'extérieur ayant une articulation avec un axe et un pédalier, l'axe ayant des bagues fabriquées avec un polyéthylène de masse moléculaire ultra-élevée (UHMWPE) traité avec du disulfure de molybdène (MoS2).
Patent WO-2023108079-A1 (WO)
Title: Axillary crutch
Inventor: YOUNGER MAX JEFFERIES
IPC: A61H3/02
Filed: 2022-12-08
Abstract: An axillary crutch includes a leg; a handle; and an axillary support secured atop the leg. The axillary support includes a lower support structure; an upper flexible layer; and a bladder disposed between the lower support structure and the layer.
Patent WO-2023122768-A1 (WO)
Title: Lime-based cement extender compositions, and associated systems and methods
Inventor: ROMANIUK NIKOLAS ANDREI
IPC: C04B28/12
Filed: 2022-12-22
Abstract: A lime-based cement extender composition, and associated systems and methods are disclosed herein. In some embodiments, the lime-based cement extender composition includes 5–20% by weight lime particles, 40–50% by weight limestone particles, and 40–50% by weight pozzolan particles. Additionally or alternatively, the lime-based cement extender composition can comprise a calcium oxide concentration of 45–65%, a magnesium oxide concentration of 0.5–2%, an iron oxide concentration of 0.5–2.0%, an aluminum oxide concentration of 2–8%, a silicon dioxide concentration of 20–40%, a potassium oxide concentration of 20,000–30,000 ppm, and a sodium oxide concentration of 10,000–20,000 ppm. In some embodiments, the lime-based cement extender composition, or product, is combined with cement to produce a cement blend for use in the mining industry as mine backfill.
Patent WO-2023146795-A1 (WO)
Title: Systèmes et procédés de notation de brillance de finition d'objet
Inventor: SCHNEIDER JAY DERRICK
IPC: G06T7/40
Filed: 2023-01-20
Abstract: La présente invention concerne un système de notation de brillance qui comprend : une caméra configurée pour capturer une image d'une surface d'un objet ; un module de notation de brillance configuré pour déterminer une valeur de notation de brillance correspondant à une brillance de la surface de l'objet sur la base des éléments suivants : une représentation de l'image ; des représentations stockées d'images stockées en mémoire ; et des notations de valeur de brillance stockées, respectivement associées aux représentations stockées ; et un module de commande d'affichage configuré pour afficher, sur un afficheur, l'image et la valeur de notation de brillance correspondant à la brillance de la surface de l'objet.
Patent WO-2023146945-A1 (WO)
Inventor: DYE MATTHEW
IPC: B66F11/04
Filed: 2023-01-26
Abstract: L'invention concerne un système de direction de véhicule pour une plate-forme élévatrice mobile de personnel ("PEMP") compacte ou un autre véhicule et un procédé pour déterminer de manière dynamique des angles de direction de roue indépendante de telle sorte qu'une géométrie de direction prédéterminée entre des roues orientables du véhicule est obtenue. Le système de direction détermine la coordination des roues indépendantes sur la base de différences d'angle des roues orientables. Les roues maître et suiveuse indépendantes du présent système ne sont pas liées mécaniquement, et l'absence de liaisons mécaniques entre les roues orientables indépendantes permet une efficacité spatiale et une précision de géométrie de direction. L'opération indépendante facilite la réception des actionneurs de direction dans des compartiments latéraux confinés, ce qui permet au mécanisme de levage de machine d'occuper un espace jusqu'à présent utilisé pour une connexion de direction mécanique entre les ensembles roues.
Patent WO-2023158711-A1 (WO)
Title: Tumor fraction estimation using methylation variants
Inventor: MELTON COLLIN
IPC: G16B20/20
Filed: 2023-02-15
Abstract: A computer-implemented method for generating a tumor fraction estimate from a DNA sample of a subject is disclosed. The method may include receiving a dataset of methylation sequence reads from the sample of the subject. The method may also include dividing the dataset into a plurality of variants. The method, may further include determining methylation states of the plurality of variants. The method may further include filtering the plurality of variants based on a bank of reference sequence reads to generate a filtered subset of variants. The bank may include reads generated from non-cancer samples and biopsy samples of a plurality of tissues of reference individuals. The counts of the methylation states of variants in the filtered subset are determined and input to a model that is trained based on recurrence rates of the variants in the reference sequence reads. The tumor fraction estimate may be generated by the model.
Patent WO-2023196323-A1 (WO)
Inventor: BURKE JOHN PATRICK
IPC: H05K3/34
Filed: 2023-04-04
Abstract: L'invention concerne un joint de micro-soudure et une conception de pochoir. Selon un mode de réalisation, un pochoir pour déposer une soudure sur une carte de circuit imprimé (PCB) comprend une pluralité d'ouvertures de pochoir, une première ouverture de pochoir de la pluralité d'ouvertures ayant une paroi d'ouverture délimitant un périmètre d'ouverture. La paroi d'ouverture est conçue pour ne pas s'étendre au-delà d'un bord externe d'une pastille de PCB disposée sur la carte de circuit imprimé, la paroi d'ouverture est également conçue pour ne pas s'étendre au-delà d'un bord externe d'une borne d'un composant de montage en surface et la première ouverture de pochoir est conçue pour recevoir une pâte à souder pour former un joint de soudure non convexe entre la pastille de PCB et la borne.
Patent WO-2023196500-A1 (WO)
Inventor: SCULLY CHRISTOPHER MICHAEL
IPC: A01G18/40
Filed: 2023-04-06
Abstract: Apparatus and methods to harvest biopolymer material, such as a mycological material comprising mycelia. The mycelia products that are harvested can be used in the food industry (for example, as an animal-based meat-substitute) and in other industries, such as textiles, packaging, and others. The present invention provides mycelial harvesting methods and systems that are repeatable and energy efficient, while providing high quality and quantity mycelium-based products.
Patent WO-2023200973-A1 (WO)
Inventor: HORTON ANDREW W
IPC: G01N33/50
Filed: 2023-04-13
Abstract: The present invention relates to complement-dependent cytotoxicity assays and methods of addition of complement to cells.
Patent WO-2023215403-A1 (WO)
Title: Procédés et dispositifs pour traiter une maladie vasculaire
Inventor: GARRISON MICHI
IPC: A61F2/915
Filed: 2023-05-03
Abstract: Déflecteur de flux comprenant un élément tubulaire auto-expansible ayant une pluralité de cellules expansibles, chacune des cellules expansibles ayant des entretoises et des ponts interconnectés. L'élément tubulaire a une configuration contrainte ayant un premier diamètre externe d'au moins 1,0 mm dimensionné pour une distribution à l'aide d'un système de distribution de déflecteur d'écoulement et une configuration étendue ayant un second diamètre externe plus grand que le premier. L'élément tubulaire a une zone d'extrémité proximale, une zone d'extrémité distale et une zone centrale située entre la zone d'extrémité proximale et la zone d'extrémité distale. Au moins la zone centrale de l'élément tubulaire est découpée au laser pour avoir une couverture de matériau d'au moins 25 % lorsque l'élément tubulaire est dans la configuration étendue. L'invention concerne également des systèmes, des dispositifs et des procédés associés pour traiter une maladie, en particulier des anévrismes intracrâniens et cérébraux par déploiement de dispositifs expansibles implantables.
Patent WO-2023225172-A1 (WO)
Inventor: SHU CHI-JIUN
IPC: H04L12/66
Filed: 2023-05-18
Abstract: An Encrypted Transport Proxy Backbone Protocol module is configured to set up ET Proxy Backbone connections with another distributed proxy device with each ET Proxy Backbone connection including multiple ET Proxy Backbone channels for transmitting ET proxy packets having different QoS classes. Each ET Proxy Backbone channel includes a separate queue. The ET Proxy Backbone Protocol module is also configured to schedule transmissions of the ET proxy packets from each respective queue; multiplex the ET proxy packets from each respective queue via the associated ET Proxy Backbone channel; perform local recovery of network impairments over the access network and perform congestion control to prevent packets from client devices and web servers from causing network congestion to the access network.
Patent WO-2023225262-A1 (WO)
Title: Machines de fabrication de sacs et procédés associés
Inventor: RYMER TIMOTHY
IPC: B65H29/60
Filed: 2023-05-19
Abstract: Une machine pour traiter une bande de matériau sous forme de sacs comprend plusieurs sections pour traiter la bande de matériau sous forme de sacs. Une section d'entrée est configurée pour recevoir un rouleau de la bande de matériau, une section d'étanchéité est configurée pour former des joints dans la bande de matériau, et une section d'enrouleur configurée pour enrouler les sacs sous forme de rouleaux de sacs peut être incluse. Une section de formation de bande configurée pour mettre en bande chaque rouleau de sacs peut être incluse. Une section de formation d'ourlet configurée pour former un ourlet dans la bande de matériau peut être incluse. Une station de déroulement de bande à tirer pour dérouler une bande à tirer pour des sacs peut être incluse. L'invention concerne en outre des procédés associés.
Patent WO-2023235482-A1 (WO)
Inventor: WIGGINS BRYAN
IPC: G01T1/185
Filed: 2023-06-01
Abstract: L'invention concerne un générateur de molybdène/technétium 99-m comportant une poudre contenant du molybdate de métal et un sorbant d'alumine. Un sorbant d'alumine préféré est une alumine en phase gamma (γ-A12O3), une alumine en phase chi (χ-A12O3), ou une combinaison de celles-ci.
Patent WO-2023239969-A1 (WO)
Inventor: VANHORN SHANE
IPC: B65H19/28
Filed: 2023-06-12
Abstract: A web transfer system (100) includes a first winder (10) with a first core thereon and a second winder with a second core thereon. The web transfer system includes a roll changer carriage (30) that is moveably mounted on a track and communicates with a carriage actuator (34). A linkage (50) is pivotally mounted to the roll changer carriage and is movable between a first and second roll transfer positions. The linkage includes a lay-on roll (60) and an auxiliary arm (66). The auxiliary arm is pivotable between a retracted and extended position. The auxiliary idler roll (38) is rotatably mounted to the auxiliary arm (66). The lay-on roll (60) and the auxiliary idler roll (38) transfer a web (W) from the first core (10C) to the second core (20C).
Patent WO-2024026080-A1 (WO)
Inventor: CUNNINGHAM-RHOADS KYLE
IPC: A63F13/245
Filed: 2023-07-28
Abstract: A computing system retrieves historical hole-by-hole data for a plurality of holes for plurality of golf tournaments for a plurality of players. The computing system clusters the plurality of holes into a plurality of clusters of hole types. The computing system generates a strokes gained metric for each hole type of the hole-by-hole data for each player. The computing system adjusts the strokes gained metric for each hole type. The computing system generates a probability of player performance of each player for each hole in the target tournament based at least one the adjusted strokes gained metric. The probability of player performance includes a probability of each player achieving each possible score for each hole. The computing system generates a projected outcome of the tournament by simulating player performance using the probability of player performance of each player.
Patent WO-2023172800-A1 (WO)
Inventor: HURRY SIMON
IPC: H04L9/32
Filed: 2023-02-09
Abstract: Un procédé comprend les étapes consistant à : transmettre, à un ordinateur d'entité d'autorisation, un message de demande d'autorisation avec un justificatif d'identité ou un jeton associé à un premier utilisateur, puis recevoir, en provenance de l'ordinateur d'entité d'autorisation, un message de réponse d'autorisation ; et, en réponse à la réception du message de réponse d'autorisation, transmettre le justificatif d'identité ou le jeton à un véhicule. Le premier utilisateur peut accéder au véhicule en présentant au véhicule un dispositif utilisateur qui contient le justificatif d'identité ou le jeton.
Patent WO-2024015864-A1 (WO)
Title: Cbl-b inhibitors and anti-pd1/anti-pd-l1 for use in the treatment of cancer
Inventor: WANG FANG
IPC: A61K31/4545
Filed: 2023-07-12
Abstract: The present disclosure relates to treatment of a subject in need thereof of comprising administering a therapeutically effective amount of a CBL-B inhibitor and a therapeutically effective amount of an anti PD-1/anti-PD-L1 agent.
Patent WO-2024015959-A1 (WO)
Title: Methods of making and using contact lenses including medicaments and stabilizers of labile components such as drugs
Inventor: DOSHI PRAFUL
IPC: G02C7/04
Filed: 2023-07-14
Abstract: The present invention recognizes that medical devices, such as but not limited to contact lenses, can be made having at least one coating made at least in part using printing technologies to provide drug storage and drug release structures, notably for hydrophobic drugs and that such hydrophobic drugs can be stabilized as to hydrolysis, heat, and a combination thereof. A first aspect of the present invention includes a packaged medical device that includes at least one drug delivery contact lens. A second aspect of the present invention includes a drug delivery contact lens. A third aspect of the present invention includes a method of making a drug delivery contact lens. A fourth aspect of the present invention includes an ink. A fifth aspect of the present invention includes a method of using a drug delivery contact lens to treat or prevent a disease, disorder, or condition of the eye.
Patent WO-2020019004-A1 (WO)
Title: Oscillating blade type turbine
Inventor: TRAN DINH THUY
IPC: F03D5/06
Filed: 2019-07-19
Abstract: The invention relates to an oscillating blade type windmill includes one or more layer blades moving in opposite directions, cutting off the windward and each layer blade having only one blade. The oscillating blade type windmill according to the present invention comprises a windward angle adjusting apparatus (2) is arranged at the root of blade (1) and shaft (3), an energy and inertia accumulator/releaser (4) of the blade (1) for accumulating energy when the blade (1) moves out of the equilibrium position (the equilibrium position is the position where the blade (1) in the vertical state), and release energy when the blade (1) has the largest angle of inclination relative to the equilibrium position, a variable speed mechanical assembly (5) converts the oscillating motion of the blade (1) into a rotary motion and increases the rotation speed, which is located between the shaft (3) and the motor (6). The windmill further includes a balance weight (7) for balancing weight; of blade (1). The outer shell (8) is located on the ground and automatically rotates blade (1) to windward by a windward angle adjusting apparatus (2), or located on a tower pillar (9), while the windmill using on the sea, lakes or rivers. Wherein the tower pillar (9) is shorter than the blade length (1) many times.
Patent DK-201570362-A1 (DK)
Title: Injector
Inventor: LARSEN STEEN BUHL
IPC: B02C18/22
Filed: 2015-06-11
Abstract: Method for fluidization (or liquidization or homogenization) of an organic slurry comprising a fluid fraction and a solid fraction, where the organic slurry is first pumped through a knife shredder pump and secondly passed through an inverted funnel having an inlet orifice having a first cross-sectional area and a second outlet area larger than the inlet orifice, where the slurry is injected into a pipe having a crosssectional area larger than the outlet area, such that the slurry is subjected to a substan tial under-pressure upon leaving the outlet.