baber/WOPTO huggingface dataset:
Patent EP-0756597-B1 (EP)
Inventor: DALES JOHN ROBERT MANSFIELD
IPC: C07D473/40
Filed: 1995-04-19
Granted: 2001-05-16
Abstract: Procédé de préparation d'un composé de la formule (A), des dérivés acyle ou phosphate de celui-ci, dans laquelle S représente hydrogène, hydroxy, chloro, alcoxy C1-6, ou phényle alcoxy C1-C6 et Ra et Rb représentent hydrogène, ledit procédé consistant: (i) à préparer un composé de formule (I) dans laquelle R1 représente alcoyle C1-6, phényle alcoyle C1-6 dans lequel le groupe phényle est éventuellement substitué; R2 représente hydrogène, hydroxy, chlore, alcoxy C1-6, phényle alcoxy C1-6 ou amino; et R3 représente halogène, alcoylthio C1-6, alcoylsulfonyle C1-6, azido, un groupe amino ou un groupe amino protégé, cette préparation comprenant les étapes consistant à faire réagir un composé de formule (II) dans laquelle R2 et R3 ont les notations données dans la formule (I), avec un composé de formule (V) dans lequel L est un groupe labile et R1 a la notation donnée dans la formule (I), afin d'obtenir un composé de formule (VI), puis à convertir le composé intermédiaire de formule (VI) en un composé de formule (I) en passant par une décarboxylation, et, si nécessaire ou souhaité, en convertissant entre elles les variables R1, R2 et R3 pour leur donner d'autres valeurs de R1, R2 et R3; (ii) à convertir le composé obtenu de formule (I) en un composé de formule (A) en convertissant la variable R3, en amino lorsqu'elle est autre qu'amino, en réduisant les groupes ester CO2R1 en CH2OH et, éventuellement, en formant des dérivés acyle ou phosphate de ce composé, et, si nécessaire ou souhaité, en convertissant la variable R2 du composé de formule (I) en variable X du composé de formule (A). Le composé de l'invention est caractérisé en ce que dans la formule (I) R2 représente chloro.
Patent EP-0769078-B1 (EP)
Inventor: KOSA THEODORE
IPC: C22C38/00
Filed: 1995-07-07
Granted: 2000-02-23
Abstract: An austenitic, stainless steel alloy having a unique combination of machinability and a low magnetic permeability, especially in the cold worked condition, is disclosed consisting essentially of, in weight percent, about -C 0.l035 max -Mn 1.0-4.0 -Si 1.0 max -P 0.2 max -S 0.15-0.45 -Cr 16.0-20.0 -Ni 9.2-12.0 -Mo 1.5 max -Cu 0.8-2.0 -N 0.035 max -Se 0.1 max -  with the balance essentially iron.
Patent EP-0784633-B1 (EP)
Inventor: ALMSTEDT ANNELIE
IPC: C07K14/755
Filed: 1995-11-14
Granted: 2005-08-17
Abstract: PCT No. PCT/SE95/01351 Sec. 371 Date May 30, 1997 Sec. 102(e) Date May 30, 1997 PCT Filed Nov. 14, 1995 PCT Pub. No. WO96/15150 PCT Pub. Date May 23, 1996A process for reducing degradation of recombinant coagulation factor VIII caused by metal-dependent proteases requiring Zn2+ for activity or containing Zn2+ as an integral part of their structure comprises adding an inhibitor of Zn2+ dependent proteases to a recombinant factor VIII solution. The recombinant factor VIII solution is obtained after harvesting a conditioned medium from a cell culture used for producing the recombinant coagulation factor VIII. The inhibitor is selected from complexing agents with a stronger affinity for the Zn2+ ion of the protease than for the ion or ions stabilizing the factor VIII molecule, and compounds structurally related to the natural substrate of the protease and containing an electronegative moiety.
Patent EP-0723949-B1 (EP)
Inventor: BORCHERT HOLGER DR
IPC: C07C45/36
Filed: 1996-01-18
Granted: 2000-04-26
Abstract: Prodn. of halo-benzaldehydes of formula (I) comprises the catalytic gas-phase oxidn. of corresp. substd. toluenes of formula (II) with oxygen in the presence of a catalyst of formula Me<1>aMe<2>bMe<3>cOx (III). Hal = F, Cl, Br or I, z = 1-4, Me<1> = Bi or V, Me<2> = Li, Na, K, Rb and/or Cs; Me<3> = Fe, Co, Ni, Nb, Mo, As, Sn, Sb, W, Ta, P, Cr, Mn, Pd, Cu, Zn, Ce, Ag, B, Sm, Ba, Ca, Mg and/or Re; when a = 1, b = 0.1-2 and c = 0.05-2, opt. with different values of b and c for different Me<2> or Me<3>; x is not defined.
Patent EP-0733612-B1 (EP)
Inventor: JANSEN ROLF-MICHAEL DR
IPC: C07C17/389
Filed: 1996-03-11
Granted: 1999-09-08
Abstract: Removal of olefin impurities from 2H-heptafluoropropane (R 227) comprises passing it in the gas phase over aluminium oxide at -20 to 100 degrees C.
Patent EP-0740998-B1 (EP)
Inventor: KEENE DARREN SCOTT
IPC: B29C39/36
Filed: 1996-04-30
Granted: 2002-09-11
Abstract: An automated means for hydrating a molded hydrophilic contact lens is provided in which a first robotic assembly removes a plurality of contact lens molds from a production line carrier, each of the lens molds having a contact lens adhered therein. The first robotic assembly transports the molds to a first staging area where the lens molds are sandwiched between a lens mold carrier and a top chamber plate to form a first hydration carrier. A first rotary transfer device then hands the first hydration carrier to a second robotic assembly which immerses the first hydration carrier in a hydration bath to hydrate the lens and to release the lens from the lens mold. While the lens is immersed in the hydration bath, each lens is transferred from its respective mold to a lens transfer means found within the top chamber plate. After a predetermined period of time, the second robotic assembly removes the first hydration carrier from the hydration bath and hands the hydration carrier off to a second rotary transfer device which rotates the first hydration carrier and aligns it for transfer to a third robotic assembly. The third robotic assembly then carries the top chamber plate and contact lenses through a series of steps in which the lens mold carrier and lens molds are removed from the top chamber plate. The lenses carried on the lens transfer means are then flushed and transported for assembly with a hydration base member to form a second hydration carrier for processing the lens in subsequent extraction stations. The second hydration carrier is then transported through a plurality of flushing or extraction stations wherein fresh deionized water is introduced into the hydration chambers at each hydration station to flush leachable substances from the hydration chamber. At each flushing station, fresh deionized water is introduced into the hydration chamber to remove previously extracted impurities and the products of hydrolysis. A final robotic dis-assembly device separates the top chamber plate and lens transfer means from the hydration base member, to provide fully hydrated lenses in a concave lens holding means ready for transfer to inspection and packaging stations.
Patent EP-0846067-B1 (EP)
Inventor: SPEZIA ALBERT JOSEPH
IPC: B60R13/10
Filed: 1996-02-07
Granted: 2001-08-01
Abstract: A frangible motor vehicle number plate or "St. Christopher's plate" with a body made of earthenware, china, glass, plastic, a composite material or any other material that will break at the first impact. The back of the plate is cut like a jigsaw puzzle. Whatever material is used to made the plate, it contains a fine wire mesh secured to the plate mountings so that the plate is held in place even when damaged. One or both sides of the plate are enclosed in a highly adhesive film. The plate is preferably made of glass, particularly laminated glass, and used as the front plate on motorcycles where the number is shown on both sides. When damaged, the plate is conspicuously so. This "St. Christopher's plate" enables the truth about driving skills to be known.
Patent EP-0879122-B1 (EP)
Inventor: HANSMA ARNOLD
IPC: C04B35/645
Filed: 1996-06-03
Granted: 2006-02-22
Abstract: A ceramic material is prepared which has a favorable combination of high density, and elevated modulus of elasticity and thermal shock resistance as measured by the ability to withstand temperature changes of at least 300° C. The ceramic material is prepared by subjecting a ceramic structure to at least one heat treatment providing the formation in the structure of controlled macro- and micro-cracks, and subjecting the structure processed in this fashion to further heating under static pressure to form the final ceramic material having the favorable combination of properties enumerated herein. The invention extends to the material, the method of its preparation and to a variety of products having predetermined properties that can be fabricated therefrom. For example, cylinder inserts for the manufacture of internal combustion engines, and packaging for integrated circuit devices may be prepared from the present ceramic material.
Patent EP-0829121-B1 (EP)
Inventor: BORCHERT BERND
IPC: H01S5/343
Filed: 1996-05-13
Granted: 1998-10-28
Abstract: L'invention a pour objet une structure de diose laser DFB à couplage de grille optique complexe, dans laquelle la grille est constituée par une couche (52) en un matériau semi-conducteur à indice volume et par une couche (53) en un matériau semi-conducteur à absorption volume, les deux couches (52, 53) étant superposées et n'étant pas mutuellement déphasées.
Patent EP-0826064-B1 (EP)
Inventor: HO CHIEN
IPC: C12N15/09
Filed: 1996-04-30
Granted: 2004-11-24
Abstract: A non-naturally occurring mutant hemoglobin ( alpha 96Val->Trp) is provided that has a lower oxygen affinity than that of native hemoglobin, but high cooperativity in oxygen binding. The mutant hemoglobin is preferably obtained by recombinant DNA techniques. Such a mutant hemoglobin may be used as a component of a blood substitute.
Patent EP-0902659-B1 (EP)
Inventor: FARIES DURWARD I JR
IPC: A61B19/08
Filed: 1996-05-02
Granted: 2003-08-13
Abstract: The present invention is directed to a method and apparatus for preventing damage to drapes and to heating and cooling mechanisms used in conjunction with apparatus for containing and thermally treating sterile liquid, and to preserving the sterile field when using such apparatus. A surgical drape is combined with a sensor, preferably attached to the drape, to detect whether or not liquid is present in a drape container conforming to a heating/cooling basin. An alternative embodiment employs sensors at opposite surfaces of the drape to measure conductance and, thereby, leakage through the drape. A microprocessor in each embodiment receives a signal representing, for example, an electrical conductance measurement from the sensors and determines if liquid is present, or alternatively if the conductance is sufficient to represent the presence of a leak. If liquid is not present or a leak is determined to exist, the microprocessor disables a temperature controller for the basin to prevent damage to the drape and heating and cooling mechanisms.
Patent EP-0839209-B1 (EP)
Inventor: VILJAVA TAPIO
IPC: C12P7/56
Filed: 1996-07-16
Granted: 2002-03-20
Abstract: PCT No. PCT/FI96/00415 Sec. 371 Date Nov. 7, 1997 Sec. 102(e) Date Nov. 7, 1997 PCT Filed Jul. 16, 1996 PCT Pub. No. WO97/04120 PCT Pub. Date Feb. 6, 1997The invention relates to a method for preparing pure lactic acid or a salt thereof by fermentation. The preparation process comprises bioreactor refreshing cycle and a lactic acid production cycle, wherein during the production cycle a solution comprising substantially pure feedstock is recycled through a bioreactor containing refreshed microorganism cells, the lactic acid produced being neutralized by adding an alkali, and the recycling is discontinued when the alkali consumption is substantially diminished, and during the refreshing cycle the microorganism cells are refreshed by recycling through the bioreactor a carbohydrate solution enriched with nutrients, thus replenishing the capacity of the microorganisms to produce an acid, and recovery of lactate or conversion thereof into lactic acid or other salt.
Patent EP-0862452-B1 (EP)
Inventor: DE YOUNG LINDA R
IPC: A61K47/10
Filed: 1996-10-21
Granted: 2003-12-10
Abstract: Formulations are provided comprising NGF and acetate-containing buffer from pH 5 to 6 that provide enhanced stability of NGF for use in promoting nerve cell growth, repair, survival, differentiation, maturation or function.
Patent EP-0857341-B1 (EP)
Inventor: SCHLAGER DAN
IPC: G08B21/02
Filed: 1996-10-28
Granted: 2008-07-30
Abstract: The system (750) includes a supervising base station (754) and remote monitoring unit(s) (752) including a navigational receiver (756) providing a remote unit location (759) and a transmitter (758) for communicating the location (759) to the base station (754) for display (772). The remote unit (752) includes sensor(s) (760) monitoring the remote location. A change in sensor status (761) results in the status and the location being transmitted to the base station (754), which includes alarms (776) and displays (772) responsive to the change in status. Various embodiments define a man-over-board system, an invisible fence system, and a weather surveillance system.
Patent EP-0876303-B1 (EP)
Inventor: DALE PARKER
IPC: C02F3/34
Filed: 1996-10-31
Granted: 2003-12-03
Abstract: A composition for the treatment of municipal and industrial waste-water. The composition comprises a yeast fermentation supernatant, preservatives and a non-ionic surfactant. In a preferred embodiment of the present invention the composition comprises a fermentation supernatant from a Saccharomyces cerevisiae culture, sodium benzoate, imidazolidinyl urea, diazolidinyl urea and a non-ionic surfactant.
Patent EP-0869903-B1 (EP)
Inventor: PALM LARS-ERIK
IPC: B65B61/24
Filed: 1996-11-05
Granted: 2002-02-06
Abstract: PCT No. PCT/SE96/01420 Sec. 371 Date Jul. 30, 1998 Sec. 102(e) Date Jul. 30, 1998 PCT Filed Nov. 5, 1996 PCT Pub. No. WO97/18995 PCT Pub. Date May 29, 1997Packaging containers for liquid contents, for example milk, are normally manufactured from laminated packaging material including a carrier or core layer of fiber material which is coated on each side with plastic layers. In order to facilitate folding of the material, this is normally provided with a pattern of weakening crease lines which facilitate the reforming into the desired packaging container configuration. A method of retroforming or calibrating a packaging container for realizing more accurate final configuration, sharper fold lines and thereby for imparting to the packaging container improved steadiness and stability comprises the steps of surrounding the packaging container (1) with a forming device (11) adapted to the final configuration of the packaging container, and of displacing parts (12, 13) of the forming device towards one another so that the free space for the packaging container is briefly reduced. An apparatus for carrying the method according to the present invention into effect comprises a forming device (11) with moving forming parts which, in the closed position, define a forming cavity of a volume which amounts to between 100 and 110 per cent of the theoretical minimum volume of a processed packaging container.
Patent EP-0865240-B1 (EP)
Inventor: ALIG BERND
IPC: C07D285/06
Filed: 1996-11-25
Granted: 2001-10-04
Abstract: The invention relates to the use of partially known 1,2,3-thiadiazole carboxylic acid (thio)esters of formula (I), in which R<1> is hydrogen, optionally substituted alkyl or optionally substituted aryl; R<2> is optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl or optionally substituted aryl; and Q is oxygen or sulphur, and the use of acid addition salts and metal salt complexes of said esters to protect plants well from attack by undesirable micro-organisms and to control animal pests. Particular 1,2,3-thiadiazole carboxylic acid (thio)esters of formula (I) are novel.
Patent EP-0789986-B1 (EP)
Inventor: MUELLER NORBERT
IPC: A01B59/00
Filed: 1997-01-18
Granted: 2000-05-24
Abstract: A housing (8) is provided in which a rod component (11) is adjustably accommodated in a hole (21) along a longitudinal axis (17). Devices are provided for fixing the rod component to the housing at a fixed length and comprise an insert bolt (24) and an insert hole in the housing. Devices are provided for adjustment of the fixed lift bar length, which comprise a threaded connection. The rod component, at least at its end extending out of the housing, has a bore section (10) with a thread in which a threaded bar (9) is adjustably inserted with its outer thread. The rod component at its end inserting in the housing is provided with a recess (13) or a hole through which the insert bolt extends.
Patent EP-0857980-B1 (EP)
Inventor: WETTEBORN HAINER
IPC: G01S17/14
Filed: 1997-12-09
Granted: 2001-10-31
Abstract: The distance measuring device has an optical transmitter (1), an optical detector (2) and an optical attenuator (11). The attenuator (11) is provided in the transmission or reception path. The device also has a time measuring unit (13) to determine the light propagation time between transmitting and receiving a light signal. The light transmitter is formed as a single unit compact module (1) in which a laser diode (17), connector elements (18) for the diode (17), a device for outputting reference pulses (19) and a fibre plug terminal (20,21) for coupling the light into an optically conducting fibre (4), are integrated. The light detector is also formed as a single unit, compact module (2) in which a photodiode, connector elements for the diode and a fibre plug connector for coupling received light in via an optically conductive fibre are integrated.
Patent EP-0949042-B1 (EP)
Inventor: BRAUN HANS-DIETER
IPC: B23Q1/01
Filed: 1997-12-18
Granted: 2002-08-21
Abstract: The machine tool has a stand (10) on which a first carriage (20) runs in one horizontal direction on rails (18,19). A second motor-driven carriage (25) on the first one moves in a second horizontal direction perpendicular to the first direction. A rotating drive device with a tool head forms a vertically immovable unit with the second carriage. A motor driven work table (30) is used for vertical motion.
Patent EP-0956084-B1 (EP)
Inventor: FISCHER DAN E
IPC: A61C5/06
Filed: 1997-01-17
Granted: 2006-04-05
Abstract: A delivery tip for use on a delivery device for applying a dental composition to tooth surfaces includes a tubular member having a proximal end and a distal end. The proximal end of the tubular member is coupled to the delivery device. A plurality of fibrous bristles are disposed on an outer periphery at the distal end of the tubular member. The fibrous bristles can be used in an agitating action to remove entrapped air bubbles from the applied composition such as an impression material. The fibrous bristles on the delivery tip can also be used to coat and spread the composition on tooth surfaces. With the fibrous bristles attached to the outer periphery at the distal end of the delivery tip, the composition can be delivered through the passageway in the tubular member without interference from the bristles.
Patent EP-0939827-B1 (EP)
Inventor: KINGSMAN ALAN JOHN
IPC: C12N5/10
Filed: 1997-10-17
Granted: 2011-08-17
Abstract: Retroviral vector particles capable of infecting and transducing non-dividing mammalian target cells, which vector particles may be based on letiviruses such as HIV and which have an RNA genome constructed so as to provide in the DNA provirus a non-lentiviral expression control element in the 5'LTR of the provirus.
Patent EP-0917515-B1 (EP)
Inventor: MEIER MICHAEL
IPC: B61L3/22
Filed: 1997-07-01
Granted: 2001-10-10
Abstract: On vehicles on which only a single receiving antenna is provided or where a plurality of receiving antennas which are arranged side by side and are coupled to the forward and return conductors of a line conductor are provided, the phase angle of the received voltage is retained when the voltage drops below a given received level. If the level of the received voltage rises again, the prevailing phase angle of the received voltage can be compared with that of the retained received voltage. If the received voltages to be compared are found to be in phase opposition, it is deduced that a line conductor intersection point has been passed; if they are in phase, transient transmission interference is inferred. The phase angle of the comparative voltage is preferably retained by a flywheel oscillator, with the time offset between the prevailing received voltage and the comparative voltage preferably being determined by weighting the peak values of the two voltages.
Patent EP-0922332-B1 (EP)
Inventor: FOGG ANDREW
IPC: G06F7/68
Filed: 1997-08-01
Granted: 2002-01-16
Abstract: A frequency-dividing circuit comprises a digital accumulator capable of performing signed arithmetic and means for adding of a predetermined numerator to the content of the accumulator. Means are provided for subtracting a predetermined denominator from the content of the accumulator and further means detect if the value held in the accumulator has become zero or negative and establishing a delay setting value dependent upon the held value. Further means convert the delay setting value into a time delay inversely proportional to the magnitude of the delay setting value and the yet further means change the state of a digital output signal on expiry of the said time delay. A corresponding method is also disclosed.
Patent EP-0946671-B1 (EP)
Inventor: FARIS SADEG M
IPC: E06B9/24
Filed: 1997-11-04
Granted: 2003-04-09
Abstract: Disclosed are liquid crystal (LC) phase-retarders and linear polarizers and methods and apparatus for making the same. The liquid crystal phase-retarder is realized by a liquid crystal film structure having one or more phase retardation regions formed therein. Each phase retardation region has an optical axis specified by the direction and depth of orientation of liquid crystal molecules along the surface of the liquid crystal film structure. The liquid crystal linear polarizer is realized by a liquid crystal film structure having a chiral phase region within which liquid crystal molecules are cholesterically ordered. One or more nematic phase regions are formed along the surface of the liquid crystal film structure within which liquid crystal molecules are oriented along a direction and to a surface depth sufficient to realize one or more phase retardation regions therein having optical axes along the direction of liquid crystal molecule orientation.
Patent EP-0946506-B1 (EP)
Inventor: CARR GRAHAM
IPC: A01N37/16
Filed: 1997-12-16
Granted: 2003-09-03
Abstract: L'invention concerne des solutions acides aqueuses dont la stabilité est maintenue pendant le stockage. Ces solutions présentent souvent une valeur de pH pouvant atteindre 1, et contiennent un peracide d'ester et/ou un peracide d'acide. Elles peuvent être obtenues en faisant réagir un diester correspondant à la formule générale R?1-O-CO-R2-CO-O-R3¿. Dans cette formule, R1 et R3 représentent chacun un groupe alkyle contenant 1 à 4 atomes de carbone qui peuvent être les mêmes ou différents, et R2 représente un groupe alkylène aliphatique éventuellement non saturé qui peut être linéaire ou ramifié, contenant 2 à 6 atomes de carbone avec du péroxyde d'hydrogène aqueux en présence d'un acide, tel que de l'acide sulfurique, et permettant à ces compositions de progresser vers des concentrations d'équilibre. En commençant avec un diester, la perhydrolyse génère un peracide d'ester qui est un peracide particulièrement efficace. Ce procédé peut être contrôlé pour produire des solutions dont la teneur en peracide est élevée et qui présentent une large plage de rapports de peracide d'ester sur peracide d'acide.
Patent EP-0942692-B1 (EP)
Inventor: SCHMOTZER HANS
IPC: A61F2/38
Filed: 1997-11-14
Granted: 2004-09-01
Abstract: PCT No. PCT/EP97/06377 Sec. 371 Date Jul. 19, 1999 Sec. 102(e) Date Jul. 19, 1999 PCT Filed Nov. 14, 1997 PCT Pub. No. WO98/20817 PCT Pub. Date May 22, 1998An implant for placing on a plateau or resection surface of a joint bone includes at least one skidshaped cup having a joint seating surface, a ventral and a dorsal end. The joint seating surface extends in a longitudinal direction and has first and second curvature radii. The first curvature radius is transverse to the longitudinal direction and, at least in a coronal area, larger than the second curvature radius transverse to the longitudinal direction and in an area, which is loaded when the joint is fully bent. The first curvature radius continuously merges into the second curvature radius within a transitional area which extends over an angular range between about 30 DEG  and about 70 DEG .