baber/WOPTO huggingface dataset:
Patent CA-2062974-A1 (CA)
Title: Determination of a mutational spectrum
Inventor: THILLY WILLIAM G
IPC: C12Q1/68
Filed: 1990-07-13
Abstract: A method of resolving (physically separating) mutant DNA from nonmutant DNA and a method of defining or establishing a mutational spectrum or profile of alterations present in nucleic acid sequences from a sample to be analyzed, such as a tissue or body fluid.  The present method is based on the fact that it is possible, through the use of DGGE, to separate nucleic acid sequences which differ by only a single base change and on the ability to detect the separate mutant molecules. The present invention, in another aspect, relates to a method for determining a mutational spectrum in a DNA sequence of interest present in a population of cells.  The method of the present invention is useful as a diagnostic or analytical tool in forensic science in assessing environmental and/or occupational exposures to potentially genetically toxic materials (also referred to as potential mutagens); in biotechnology, particularly in the study of the relationship between the amino acid sequence of enzymes and other biologically-active proteins or protein-containing substances and their respective functions; and in determining the effects of drugs, cosmetics and other chemicals for which toxicity data must be obtained.
Patent CA-2063043-A1 (CA)
Inventor: MAEHARA NAOYOSHI
IPC: H02M1/00
Filed: 1992-03-13
Abstract: An electric cooking apparatus comprises a power converter which power-converts the amounts of power supplied from an external power source and an incorporated battery to be supplied to a heating energy radiating device.   The cooking apparatus, which can generate high heating energy output exceeding the current capacity, can realize high speed cooking.
Patent CA-2064994-A1 (CA)
Title: Impervious article with a microporous surface and process for its production
Inventor: PAGE ROGER
IPC: G01N33/543
Filed: 1992-04-02
Abstract: ABSTRACT   An impervious article in which molecules of a polymeric microporous structure are enmeshed with molecules of all impervious polymeric support. The preferred article is a sheet of impervious polyamide carrying a microporous polyamide layer on at least part of its surface.
Patent CA-2065029-A1 (CA)
Title: Therapeutic compositions; methods for treatment of hiv infections
Inventor: VITETTA ELLEN S
IPC: A61K47/48
Filed: 1990-09-14
Abstract: Disclosed are methods and compositions for the treatment of HIV  infections through the specific elimination of cells which express HIV env determinants such as gp120. The compositions of the invention include toxin conjugates composed of a CD4 derived gp120 binding ligand conjugated to a toxin A chain moiety such as ricin A chain or deglycosylated ricin A chain. Where a therapeutic composition is desired, the conjugates are formed by means of a cross linker which includes a disulfide bond. Disulfide linkages are not crucial where non-therapeutic uses, such as antibody generation, are intended. In preferred aspects of the invention, therapeutic amounts of conjugates composed of soluble CD4 or a CD4 peptide cross-linked to deglycosylated A chain by means of an SMPT  linker is administered to a HIV infected patient so as to specifically eliminate HIV infected cells without exerting significant toxicity against uninfected or class II cells.
Patent CA-2065688-A1 (CA)
Title: Eccentric roller control apparatus
Inventor: NISHIMURA YOICHI
IPC: G05D5/03
Filed: 1992-04-09
Abstract: An  eccentric  roller  control  apparatus  is intended to eliminate the adverse effect of the eccentric upper and lower back-up rollers against a product profile with high precision.   The rolling weight sensors 7W, 7D sense each rolling weight of a working side and a driving side.   The rotary angles of the upper back-up roller 4T and  lower  back-up  roller  4B are  sensed by  the  angle sensors 8T, 8B.  The roller eccentricity sensor 14 serves to derive each of the amplitudes ATWn, BTWn, ABWn, BBWn, ATDn, BTDn, ABDn and BBDn as each roller eccentricity of the working  side  and  the  driving  side,  based on  the sensed rolling weights PW, PD and the rotary angles .theta.T and .theta.B.   Then, the depression operating unit 15W serves to derive the depression of the working side and add the derived value to the depressor control device 6W.   The depression  operating  unit  15D  serves  to  derive  the depression of the driving side and add the derived value to the depressor control device 6D.
Patent CA-2067357-A1 (CA)
Title: Nmr apparatus and method for detecting cancer
Inventor: FOSSEL ERIC T
IPC: G01R33/465
Filed: 1990-10-04
Abstract: A technique and an apparatus are disclosed for the detection of cancer using nuclear magnetic resonance (NMR). Specifically, NMR  parameters for protons of lipid methyl and/or methylene groups are determined and compared against a corresponding value for healthy patients. In the preferred embodiments, an improved NMR  spectrometer is employed to provide a spectrum for non-water components of blood, blood serum or blood plasma and the width of the methyl and/or methylene groups is automatically measured at half-height as a determination of spin-spin relaxation time (T2) which is the parameter used for purposes of comparison with healthy controls. In the event that a positive reading is obtained, the level of plasma triglycerides is determined and if it is high, the patient's bodily fluid sample is further subjected to C-13 nuclear magnetic spectroscopy.
Patent CA-2070568-A1 (CA)
Title: Method and apparatus for metering and blending different material ingredients
Inventor: MOLLER RICHARD W
IPC: B29C48/92
Filed: 1992-06-05
Abstract: A plurality of individual plastic material ingredients are metered from respective individual material hoppers at controllable individual discharge rates, blended, and delivered to a common hopper. The blend of plastic material ingredients in the common hopper is discharged to an extruder or other material processing machine. The material processing rate of the processing machine is determined based on the sum of the discharge rates of the individual ingredients to the common hopper plus or minus the discharge rate of the blend from the common hopper to the processing machine. The discharge rates of the individual material ingredients from the individual hoppers to the common hopper is controlled as nestled to maintain a preset recipe of the blend at the determined material processing rate of the processing machine.
Patent CA-2072243-A1 (CA)
Title: Method and apparatus for extracting a cement mantle from a bone recess
Inventor: MOLL FREDERIC H
IPC: A61F2/36
Filed: 1992-06-24
Abstract: ABSTRACT OF THE DISCLOSURE      A method and apparatus for removing a pre-placed prosthetic appliance anchored in place in a bone recess by a cement mantle and conditioning the recess for receipt of a replacement appliance.  The pre-placed appliance is first pulled from the mantle of hardened cement holding it within the recess thus leaving a cavity within the mantle.  A screw threaded post having nuts threadably engaged therewith at longitudinally spaced locations is then anchored within the cavity with a new mass of cement. Thereafter, the post is threadably disengaged from the nuts, leaving the nuts in place within the new mass of cement.  A pulling tool is then successively engaged with the nuts and tensioned to incrementally remove the mantle from the recess.
Patent CA-2076934-A1 (CA)
Title: Multiple part business form and related process
Inventor: LOCH MARK D
IPC: B42D5/02
Filed: 1992-08-26
Abstract: ABSTRACT      A business form (and related process) includes a web folded medially to form two plies secured one to another about their marginal edges with a third ply secured about three of its four edges to one of the first and second plies forming a return envelope. The edges of the third ply are offset inwardly relative to the edges of the first and second plies. A fourth insert ply is adhesively secured between the first and third plies along only two of its transverse and longitudinal edges.  The two edges are substantially aligned with two of the edges of the second ply, leaving two other edges of the fourth ply inwardly offset from the remaining edges of the second ply.
Patent CA-2078405-A1 (CA)
Title: Compensation for Skewing of Documents During a Rotation Through a Finite Angle
Inventor: KALISIAK MICHAEL S
IPC: B65H9/10
Filed: 1992-09-16
Abstract: The skew angle of a sheet (e.g., business form or other document) is detected by providing two sensors spaced from each other a known distance along a straight line perpendicular to the direction of conveyance of the sheet.  If there is a skew, the distance travelled by the sheet leading edge between sensings by the sensors is determined, and the skew angle calculated from its tangent.  First and second independent drive rollers under the sheet are driven in opposite directions of rotation to compensate for the skew angle.  The rollers preferably act in conjunction with a controller (computer) to not only reorient the sheet to compensate for the skew, but also to rotate the document through a significant angle (e.g., 90°) to give the sheet a second orientation different from its initial orientation (e.g., from portrait to landscape).
Patent CA-2080655-A1 (CA)
Title: Blades for snow-removal vehicles and vehicles therewith
Inventor: COTE MARIO
IPC: E01H5/04
Filed: 1992-10-15
Abstract: Blades for snow-removal vehicles and vehicles therewith Abstract Blades are used in association with snow buckets articulated from snow-removing vehicles. In a preferred embodiment, the snow bucket comprises rotatably mounted about its lateral sides, a floating snow blade outwardly projectable substantially horizontally in front of the lower portion of each of the side walls of the bucket, as to float according to the conformation thereunder and to confine and to force the snow between the snow blades and the bucket to enter the bucket and to shovel it and thereby increasing the snow content of a bucket per stroke. Preferably, the floating snow blades are outwardly projec-table substantially horizontally in alternation, in front of or in the back of, the lower portion of each of said side walls.
Patent CA-2081223-A1 (CA)
Title: Microfine melt flow rate polymer powders and process for their preparation
Inventor: HEIMBERG MANFRED
IPC: C08F230/08
Filed: 1992-10-23
Abstract: ABSTRACT The present invention relates to crosslinkable microfine ethylene copolymer powder which are substantially spherical in shape and range in size from about 10 up to about 500 microns and to the process of crosslinking the powders to reduce their melt flow rate. The powders are crosslinked by contacting with water in the presence of a silanol condensation catalyst at temperatures from ambient up to about 110°C. The reduction in melt flow rate is accomplished without substantially changing the powder characteristics, i.e., particle size and particle size distribution.
Patent CA-2082856-A1 (CA)
Title: 3-sulfonylamino-2-(1h)-quinoleinone derivatives, process for their preparation and pharmaceutical compositions containing them
Inventor: CORDI ALEX
IPC: C07D409/12
Filed: 1992-11-13
Abstract: Compounds of formula (I): <IMAGE>  in which:     X, Y, Z   - which are identical or different, represent a hydrogen atom, a halogen atom or a nitro, cyano, azido, trihalomethyl, linear or branched (C1-C6)alkyl, linear or branched (C1-C6)alkoxy, or amino (unsubstituted or substituted by a linear or branched (C1-C6)acyl group) group, - or else, when they are situated on two adjacent carbons, form, with the carbon atoms to which they are attached, a phenyl ring or a 5- or 6-membered heterocycle containing from 1 to 3 hetero atoms, preferably a 1,2,5-oxadiazole ring,   R represents a linear or branched (C1-C6)alkyl, trihalomethyl, phenyl (unsubstituted or substituted by one or a number of halogen atoms or linear or branched (C1-C6)alkyl, trihalomethyl or linear or branched (C1-C6)alkoxy groups), 2-thienyl (unsubstituted or substituted by a halogen atom), naphthyl or styryl group,   A represents a CH radical or a nitrogen atom.   Medicaments.
Patent CA-2088349-A1 (CA)
Title: Apparatus for the classification of a pattern for example on a banknote or a coin
Inventor: BAUDAT GASTON
IPC: G07D7/20
Filed: 1993-01-28
Abstract: ABSTRACT         An apparatus for the classification of a pattern, in particular on a banknote or a coin, has a receiving system for detecting by a measurement procedure vectors of a test item, a pre-processing system for transformation of the measured vectors into local feature vectors ALCi(1) and a learning classification system (8)  for carrying out a plurality of testing operations.  A first activity (14) compares in a first testing operation each of the local feature vectors ALCi(1) to a vectorial reference value.   It is only if the first testing operation takes place successfully that the first activity, by means of first estimates which are stored in a data base,  links the local feature vectors ALC(1) to provide global line feature vectors AGIi.  In a second testing operation a third activity (18) compares the global line feature vectors  AGIi  to corresponding reference values  and,  if  the second testing operation is successful, computes a single global surface vector AGF of which a fourth activity (21),  in a third testing operation, compares  its distance in accordance with Mahalanobis relative to an estimated   surface vector to a reference value.  The test    item is reliably  classified  if  all  three  testing  operations take  place successfully.
Patent CA-2090076-A1 (CA)
Title: Method for improving primary memory and/or learning
Inventor: CLEMENS JAMES A
IPC: A61P25/28
Filed: 1993-02-22
Abstract: ABSTRACT OF THE DISCLOSURE     A method for improving primary memory or learning in a mammal comprising administering a 5-hydroxytryptamine receptor agonist which is selective for the 5-hydroxytryptamine-1A receptor subtype, or a pharmaceutically acceptable salt thereof.
Patent CA-2090659-A1 (CA)
Inventor: BIELAGUS JOSEPH B
IPC: B09B5/00
Filed: 1993-03-01
Abstract: An opening device for opening bagged refuse to liberate the contents of the bag, in which garbage bags are transported along a conveyor, and a plurality of endless chains having tines attached thereto are operated above the conveyor.  As bags pass under the endless chains, tines extending downwardly from the chains pierce the garbage bags.          Adjacent chains are operated at different speeds, and the tines move at different speeds relative to the conveyor, tearing the bags, liberating the refuse.
Patent CA-2091488-A1 (CA)
Title: Method and apparatus for the orientation of a plastic pipe
Inventor: JAERVENKYLAE JYRI
IPC: B29C48/13
Filed: 1993-03-11
Abstract: A method and an apparatus for the orientation of a plastic pipe, wherein a pipe blank (2) is produced with an extruder and fed into a pipe forming apparatus provided with movable moulds (3), such as a corrugator, the pipe being conveyed forward in the corrugator with said moulds over a mandrel (4), along which the pipe is further conveyed out from the corrugator. In accordance with the invention, the plastic pipe (7) is oriented radially immediately after the corrugator by means of a conically widening mandrel (5) forming an extension of said corrugator. The invention also relates to an oriented ribbed plastic pipe produced by the method.
Patent CA-2091789-A1 (CA)
Title: Method of inhibiting microvascular thrombosis
Inventor: KHOURI ROGER K
IPC: A61P7/02
Filed: 1993-03-17
Abstract: A method for reducing the thrombogenicity of microvascular anastomoses in a warm blooded mammal comprising administering to said mammal at the site of said microvascular anastomoses contemporaneously with microvascular reconstruction of a small but inhibitory effective amount of TFPI.
Patent CA-2094031-A1 (CA)
Title: Electronic braking system for power press die change carriers
Inventor: OSTER EUGENE A
IPC: B60L9/16
Filed: 1991-10-18
Abstract: The invention provides an automatic die changing system for a power press (10) with at least one carrier (28) for transporting dies to and from a selected location in the press. The carrier is supported on a set of wheels (30), which are driven by at least one AC induction motor (50). An adjustable frequency AC motor drive (56) supplies an AC frequency and voltage to the AC induction motor to control the speed of the motor and therefore the speed of a horizontal movement of the carrier into or out of the press. The speed of the carrier may be rapidly increased by increasing the AC frequency supplied to the motor on the individual wheels. A  proximity detector (60) signals the motor drive to trip a dynamic braking resistor (58), which electronically changes the phase order of the motors to reverse the direction of motor rotation, to decelarate the carrier in order to locate the carrier in the proper position.
Patent CA-2095458-A1 (CA)
Inventor: FUHRMAN WILLIAM J
IPC: B21H5/02
Filed: 1993-05-04
Abstract: ABSTRACT          A method of preparing a gear blank for roll-finishing, essentially comprising the step of: while supporting a gear blank with pitch-line chucking, finish-sizing the central axial opening of the gear blank to a desired concentricity to promote accurate subsequent roll-finishing.  Also, a method of making roll-finished gears, comprising: (a) preparing a near-net-shape gear blank, with external gear teeth and a central axial opening, by intimately engaging and supporting the gear blank between two opposing roll-finishing gear dies, without teeth finishing pressure; (b) finish-sizing the sides of said axial opening to attain a concentricity between the gear blank's intended tooth pitch circle and said sized sides that is within the range of .001 inch TIR; and (c) inserting a snugly fitting arbor into said opening and completing roll-finishing of the gear blank by progressively bringing the roll-finishing dies together to exert teeth finishing pressure and rotating said dies to form the desired gear teeth on said gear blank.
Patent CA-2095853-A1 (CA)
Title: Detergent compositions
Inventor: LINDEGAARD POUL
IPC: C12N9/56
Filed: 1991-11-14
Abstract: This invention relates to detergent compositions. More specifically, the invention relates to detergent compositions containing alkyl sulphate and one or more subtilisins or subtilisin variants, which subtilisins or subtilisin variants either in position 195 hold a glutamic acid residue, or in position 222 hold an alanine residue, or both.
Patent CA-2098266-A1 (CA)
Title: Recovering hydrocarbons
Inventor: VINEGAR HAROLD J
IPC: E21B43/24
Filed: 1993-06-11
Abstract: A process to recover hydrocarbons is provided wherein a hydrocarbon-containing subterranean formation (1) is heated by conductive heat transfer from a heat injector well (3) operating at temperatures above 900 °C. The high temperature levels of this process result in high recoveries of initial hydrocarbons in place, and recovery of the hydrocarbons within a short time period. This process is particularly applicable to diatomite formations which have low permeabilities.
Patent CA-2098473-A1 (CA)
Title: Imidazopyridines
Inventor: MEDERSKI WERNER DR
IPC: A61P25/00
Filed: 1993-06-15
Abstract: Abstract of the Disclosure Novel imidazopyridine derivatives of formula I:                                 I wherein R   is   and R1, R2, R3, R4, X and Y are as defined in Patent Claim 1,  and their  salts,  exhibit  antagonistic  properties towards angiotensin II and can be used for the treatment of hypertension, aldosteronism, cardiac insufficiency and increased intraocular pressure, and of disorders of the central nervous system.
Patent CA-2099551-A1 (CA)
Inventor: MARKYVECH RONALD K
IPC: F16H59/14
Filed: 1993-07-02
Abstract: A control system/method for an at least partially automated mechanical transmission system (10) is provided for determining if selected upshifts into a target gear ratio are acceptable (208) or not acceptable (210) under current vehicle operating conditions and for prohibiting the initiation of not acceptable selected upshifts. An upshift is deemed acceptable if the available drivewheel torque (206) in the target ratio is sufficient to maintain at least a minimum acceptable vehicle acceleration (A0) after the upshift under current vehicle operating conditions. <IMAGE>
Patent CA-2099693-A1 (CA)
Title: System and method for removing hydrocarbons from gaseous mixtures using multiple adsorbing agents
Inventor: HERTL WILLIAM
IPC: F01N3/08
Filed: 1993-06-29
Abstract: ABSTRACT OF THE DISCLOSURE      A system and method are disclosed for removing hydrocarbons from a gaseous mixture, which comprises selecting a plurality of agents which are effective for adsorbing hydrocarbons at predetermined temperatures, wherein for at least two of the adsorbing agents, the temperatures at which the maximum adsorption rates for the hydrocarbons occurs, are different from one another, and contacting the adsorbing agents with the gaseous mixture at the predetermined temperatures to cause adsorption of the hydrocarbons.  A multi-stage catalyst system for converting NOx, CO, and hydrocarbons from a gaseous mixture to innocuous products is disclosed, which comprises the above described system for removing hydrocarbons as one stage, and a main body catalyst stage for converting NOx, CO, and hydrocarbons to innocuous products, wherein the gaseous mixture passes from one stage to the other.
Patent CA-2101571-A1 (CA)
Title: Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
Inventor: GAROFALO ELIZABETH A
IPC: A61P31/04
Filed: 1993-07-29
Abstract: ABSTRACT    The present invention relates to a new crystalline dihydrochloride dihydrate salt of the cephalosporin antibiotic, cefepime.  In particular, this invention provides a temperature and moisture stable crystalline dihydrochloride dihydrate form of cefepime having enhanced stability and a specific x-ray powder diffraction pattern as described herein. The present invention also provides physical admixtures of the new crystalline dihydrochloride dihydrate salt of cefepime with a pharmaceutically acceptable non-toxic organic or inorganic base. In particular, this invention provides physical admixtures of a temperature and moisture stable crystalline dihydrochloride dihydrate form of cefepime having a specific X-ray powder diffraction pattern as described herein with L(+) arginine.
Patent CA-2105377-A1 (CA)
Title: Battery powered line trimmer
Inventor: EVERTS ROBERT G
IPC: A01D34/416
Filed: 1992-02-10
Abstract: A battery powered line trimmer (10) possessing a relatively high ratio of mass moment of inertia about a vertical axis ex-tending through its center of gravity to mass, The device comprising a motor and head assembly at the forward end (14) and a rechargeable battery pack (24) at the rearward end of a support shaft (16).  Also, adjustable handles (28, 30), for supporting the line trimmer (10), attached about either side of the center of gravity.
Patent CA-2106563-A1 (CA)
Title: Cocaine derivatives and protein and polypeptide cocaine derivative conjugates and labels
Inventor: BUECHLER KENNETH F
IPC: G01N33/94
Filed: 1992-12-16
Abstract: Compounds are provided for the preparation of reagents, including labels which can be used in immunoassays of cocaine and cocaine metabolites. The compounds are derivatives of cocaine which are conjugated to antigenic proteins or polypeptides for the formation of antibodies for use in immunoassays. The compounds also may be conjugated to labels for use in immunoassays.
Patent CA-2107136-A1 (CA)
Title: Lubrication system for valve seat of a gate valve
Inventor: LANNING WILLIAM W II
IPC: F16K3/36
Filed: 1993-09-28
Abstract: ABSTRACT OF THE DISCLOSURE      A lubrication system for the block and bleed valve seat of a gate valve.   Lubrication is provided to the seat through tubing which communicates with the exterior of the gate valve to supply the lubricant and the interior channels of the valve seat.  Seals in the valve seat maintain the lubricant within the interior channels of the seat.  The lubrication system allows the user to test each seat for integrity without exposing the entire valve to atmosphere by increasing lubricant pressure through the valve seat.