baber/WOPTO huggingface dataset:
Patent CA-3003304-A1 (CA)
Title: Neoepitopes viraux et utilisations de ces derniers
Inventor: NGUYEN ANDREW
IPC: G16B45/00
Filed: 2016-10-12
Abstract: L'invention concerne des traitements anticancéreux/antiviraux comprenant l'analyse de néoépitopes de l'ADN viral qui s'est intégré dans le génome dudit hôte, et la conception d'agents immunothérapeutiques dirigés contre ces néoépitopes.
Patent CA-3006311-A1 (CA)
Inventor: MAMMEN DAVID
IPC: A01F12/44
Filed: 2018-05-28
Abstract: A high strength sieve which is lightweight and durable without having to add springs, and without requiring a high level of force to effect adjustment of the louvers. The high strength sieve utilizes hollow tubes to support the louvers. Providing hollow tubes (i.e., rather than solid wires) allows for larger diameter holes to be used in the frame. This provides for increased bearing surfaces, as well as provides for better tolerances. This reduces the movement of the tubes within the holes. Preferably, the tubes are mounted in the frame through holes which are extruded, thereby providing for increased bearing surfaces and a tighter fit. The extruded holes also provide a natural lead-in for the insertion of the tubes (i.e., during assembly of the sieve). Alternatively, solid wires can be provided extending through the extruded holes instead of hollow tubes.
Patent CA-3007135-A1 (CA)
Inventor: QIAN XUEMING
IPC: C12N15/13
Filed: 2017-02-10
Abstract: An isolated PD-L1 antibody whose binding to PD-L1 at acidic pH is substantially lower than its binding to PD-L1 at neutral pH at the same assay setting and an isolated PD-L1 antibody that is not pH dependent in binding to PD-L1 are provided. The pharmaceutical composition of the antibody, encoding polynucleotide and expression vector, isolated host cell thereof as well as a kit comprising the PD-L1 antibody are also provided. Also provided herein are methods of treating a PD-L1 associated condition using the PD-L1 antibody.
Patent CA-3009597-A1 (CA)
Inventor: SCHMIDT FRIEDRICH GEORG
IPC: C07D335/00
Filed: 2017-01-20
Abstract: The invention relates to a novel hetero-diels-alder cross-linker, to methods for the production thereof and use thereof for reversibly crosslinked polymer systems.
Patent CA-3010412-A1 (CA)
Inventor: VALGEPEA KASPAR
IPC: C12N1/20
Filed: 2016-12-02
Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.
Patent CA-3010703-A1 (CA)
Inventor: BACKFOLK KAJ
IPC: C01F11/18
Filed: 2017-02-10
Abstract: The present invention relates to crystalline and stable amorphous CaCO3 precipitated on lignocellulosic fibers.
Patent CA-3012135-A1 (CA)
Title: Weak rope fishing trap locator
Inventor: BELZILE LUC
IPC: A01K69/06
Filed: 2018-07-23
Abstract: This invention called "Weak Rope Fishing Trap Locator" was developed to eliminate sea creatures, mainly Whales, to get entangled in the ropes used to link fishing traps to their buoy.  Currently the trap is link to the buoy with a relatively heavy rope; this rope has to be strong enough to retrieve the trap without breaking. Being that strong creates a problem when a sea creature gets entangled in it, often causing deadly injuries.
Patent CA-3016113-A1 (CA)
Inventor: KURIYAMA TAKUYA
IPC: A61K6/838
Filed: 2017-03-01
Abstract: The present invention provides a dental material containing nanofibers and a biocompatible resin. In one embodiment, this dental material is an implant material, prosthetic material, or denture material and has mechanical strength suited to the site of use in the body as well as exceptional dimensional stability and exceptional wear resistance. Because the compressive strength can be controlled, excessive burden on the teeth when occlusal force is applied is suppressed when the dental material is used in the oral cavity. In addition, secondary caries can be suppressed because the antimicrobial properties make plaque less likely to adhere to the teeth and make the teeth less likely to be affected by bacteria. This dental material can be used without modification as a desired dental material, and can also be made into a desired dental material by molding as needed. In addition, materials produced from these nanofibers and this resin can also be used in applications other than dental materials.
Patent CA-3017941-A1 (CA)
Inventor: KRAEMER JEFFREY ALBIN
IPC: G06F21/52
Filed: 2017-03-13
Abstract: L'invention concerne un procédé et un système permettant de remédier à une intrusion dans un espace de processus sur un dispositif d'utilisateur, comprenant la détection d'un processus commençant sur le dispositif d'utilisateur, la préparation du processus pour surveiller les appels d'une interface de programmation d'application (API) entre le processus et un système d'exploitation du dispositif d'utilisateur, de déterminer si le processus est associé à un processus de suppression d'intrusion sur la base d'informations associées au processus et/ou aux appels d'API, et d'exécuter des politiques de sécurité contre le processus associé à l'intrusion d'évidement de processus. Dans des exemples, il est déterminé si le processus fils est associé à une intrusion d'évidement de processus en réponse à la détermination si un ou d'autres appels d'API associés à des intrusions dans le processus de processus connues modifient la mémoire exécutable et/ou modifient une adresse de point d'entrée du processus fils.
Patent CA-3018895-A1 (CA)
Title: Method and apparatus for delivering a therapeutic substance through an injection port
Inventor: WALTERS MICHAEL R
IPC: A61M39/02
Filed: 2007-12-06
Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and aasures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.
Patent CA-3021152-A1 (CA)
Title: Inhibiteurs des meprines alpha et beta
Inventor: WERMANN MICHAEL
IPC: A61K31/16
Filed: 2017-04-18
Abstract: La présente invention concerne de nouveaux dérivés d'acide hydroxamique utilisés comme inhibiteurs de la méprine ß et/ou a, des compositions pharmaceutiques comprenant ces composés, des méthodes de traitement ou de prophylaxie de maladies ou d'affections, en particulier celles qui sont liées à la méprine ß et/ou a, et des composés et des compositions pharmaceutiques destinés à être utilisés dans ces méthodes.
Patent CA-3025199-A1 (CA)
Inventor: VAUGHAN DION
IPC: C22B34/12
Filed: 2017-05-24
Abstract: A method and an apparatus for manufacturing a metallic article involve providing a non- metallic feedstock, for example in the form of an oxide of a desired metal or a mixture of oxides of the components of a desired metal alloy. A manufacturing apparatus has a reduction apparatus for electrochemically reducing the feedstock to a metallic product and a processor for converting the metallic product to a metallic powder. The powder is fed into an additive-manufacturing apparatus for fabricating the metallic article from the metallic powder. At least the reduction apparatus and the processor, and preferably also the additive-manufacturing apparatus, are collocated, or located in the same container, or in the same building, or on the same site.
Patent CA-3027083-A1 (CA)
Title: Sac d'emballage souple en plastique thermosoudable antiderapant et ses procede et appareil de production
Inventor: MANDZSU JOZSEF
IPC: B29C70/64
Filed: 2017-04-20
Abstract: Sac d'emballage en plastique thermosoudable antidérapant (16), formé à partir d'un matériau d'emballage souple antidérapant (35) dont la paroi (45) a un poids de surface moyen de 500 g/m2 au maximum. Le matériau d'emballage (35) comprend une multiplicité de saillies antidérapantes (7) séparées, réparties de manière aléatoire, d'une première substance. La hauteur de saillie (11) est comprise entre 50 micromètres et 10000 micromètres, une moyenne des rapports de forme de vue en plan supérieur des protubérances antidérapantes (7) étant de 5,0 au maximum. Certaines saillies antidérapantes (7) comportent une partie de surface cachée (12) qui est une partie d'une surface libre de la saillie antidérapante (7) que la saillie antidérapante (7) cache d'un observateur sur une vue en plan supérieur de la paroi (45). La première substance est un polymère thermoplastique, et la surface extérieure (46) de la paroi est constituée d'une substance au moins quelque peu différente de la première substance. Il est important que la première substance ait un débit massique en fusion d'au moins 0,6 g/10 min. Un appareil, pour produire le matériau d'emballage (35), comprend une tête (24) de moule de soufflage de film, un anneau d'air de refroidissement (1) et une unité de dispersion de particules (38) entre ceux-ci, pour disperser les particules polymères (36) sur le col de bulle (21) à un emplacement dans, ou étroitement sous, une zone d'expansion (25) où la bulle (19) a une forme divergente.
Patent CA-3029271-A1 (CA)
Inventor: BALTES NICHOLAS
IPC: C12N15/82
Filed: 2017-06-28
Abstract: Materials and methods for changing expression of a gene product in a plant are provided, and in an embodiment for creating herbicide tolerant plants are described herein. The methods provide for inserting into a plant genome, at a different locus than an endogenous gene, a genomic or coding sequence of the gene, which may be modified, into a genetic location that is different from the endogenous gene and where there is a desired transcriptional activity. The methods described herein can include the targeted insertion of an endogenous 5-enolpyruvylshikimate-3-phosphate synthase gene into a genomic locus that enables sufficient expression to confer herbicide tolerance.
Patent CA-3031877-A1 (CA)
Inventor: SUGIMOTO HIROMI
IPC: H01M8/12
Filed: 2016-07-29
Abstract: This fuel cell is provided with a metallic supporting plate, a cell structure, a separator, a glass seal member, and a coating layer. The cell structure has an electrolyte layer disposed on the metallic supporting plate. The separator is disposed on the cell structure. The glass seal member is disposed between the metallic supporting plate and the separator, said glass seal member being disposed further toward the outer side than the cell structure. The coating layer is disposed between the metallic supporting plate and the glass seal member, said coating layer being in contact with the metallic supporting plate and the glass seal member. A predetermined gap is provided between the cell structure and the coating layer.
Patent CA-3032489-A1 (CA)
Title: Medical instrument with cleaning gap in the closure region
Inventor: GABELE LORENZ
IPC: A61B17/28
Filed: 2017-09-06
Abstract: The invention relates to a medical instrument (1) with a first hand lever (2) which has a manually actuated grip portion (3) at its proximal end, a work portion (4) for gripping, clamping or cutting an object at its distal end, and, lying between these, a bearing portion (5) on which a bearing element (6) engages in order to permit pivotability about a rotation axis (7) between the first hand lever (2) and a second hand lever (8), wherein the second hand lever (8) has a grip portion (9) at its proximal end, a work portion (10) at its distal end, and, lying between these, a guide portion (11) on which the bearing element (6) engages, wherein the guide portion (11) of the second hand lever (8) has on one side a recess (12) for receiving the bearing portion (5) of the first hand lever (2) such that two guide protrusions (13, 14) located distally and proximally of the recess (12) at least partially cover the bearing portion (5) in an operating position in which gripping, clamping or cutting takes place, wherein the bearing portion (5) of the first hand lever (2) is pressed, by means of a spacing element (23) that provides distance through force or resistance, away from the guide portion (11) of the second hand lever (8) in the operating position, such that a cleaning gap (27) between the first hand lever (2) and the second hand lever (8) extends along the entire length of the guide portion (11).
Patent CA-3034353-A1 (CA)
Title: Procede de preparation d'un produit d'hydrolysat de soja presentant une concentration elevee en acides amines libres et procede pour son utilisation
Inventor: KROH FRANKLIN O
IPC: C05F11/00
Filed: 2017-08-21
Abstract: La présente invention concerne un procédé de production d'une composition d'hydrolysat de soja présentant une concentration élevée en acides aminés libres et un procédé d'utilisation de la composition d'hydrolysat résultante. L'hydrolysat de soja à concentration élevée en acides aminés libres est utilisé pour augmenter la population microbienne trouvée dans le sol et les eaux usées. La population augmentée de microbes peut favoriser la croissance des plantes, en particulier pour une utilisation dans les zones de friche et les sites de réhabilitation similaires ou sur les pelouses, et peut favoriser la digestion des matières solides contenues dans les eaux usées.
Patent CA-3036922-A1 (CA)
Inventor: KORNELIUSSEN JAN TORE
IPC: G06T5/20
Filed: 2017-09-26
Abstract: Systems and methods are provided for reducing bias introduced from various image signal processors (ISP) or ISP components while effectively reducing noise. ISP biases include biases from spatial noise filtering, high dynamic range (HDR) interpolation, and demosaicking among others. Specifically, the methods and systems of this disclosure employ a convex combination of multiple input frames or blocks of pixels, to effectively reduce bias from a spatial noise filter, a debaver unit, or other ISP componentswww, thereby providing improved spatiotemporal noise reduction solutions.
Patent CA-3036967-A1 (CA)
Inventor: PALMER NIELS
IPC: A23P10/20
Filed: 2017-09-14
Abstract: L'invention concerne un procédé de production de protéines agglomérées, de poudres de protéines agglomérées et de poudres de protéines solubles à l'aide d'au moins un liant protéique pour former des agglomérats d'au moins une protéine cible.
Patent CA-3037470-A1 (CA)
Title: Vehicule a conduite autonome, methode d'arret d'un vehicule a conduite autonome et programme
Inventor: UMETANI HIDEO
IPC: G08G1/16
Filed: 2017-12-14
Abstract: L'invention concerne un véhicule autonome (1) comprenant : un véhicule proprement dit (10); une unité de détection de geste servant à détecter un geste d'une personne présente à proximité d'une route sur laquelle le véhicule proprement dit se déplace, ledit geste visant à arrêter le véhicule proprement dit; une unité d'évaluation servant à évaluer si un passager est dans le véhicule proprement dit ou non; et une unité de commande (20) servant à entraîner le véhicule proprement dit de manière autonome. Si l'unité de détection de geste détecte une personne faisant des gestes quand l'unité d'évaluation évalue qu'aucun passager ne se trouve dans le véhicule proprement dit, l'unité de commande amène le véhicule à s'arrêter à proximité de la personne.
Patent CA-3042135-A1 (CA)
Title: Detection and treatment of demyelinating diseases
Inventor: SEDAGHATI MAHMOUD
IPC: C07K14/435
Filed: 2017-11-01
Abstract: The present invention relates to methods of detecting, diagnosing and distinguishing between demyelinating diseases such as Multiple Sclerosis. The present invention also relates to methods of treating, and peptides for use in the treatment of, demyelinating diseases such as Multiple Sclerosis.
Patent CA-3043205-A1 (CA)
Title: Toothbrush bristle and bristle tuft
Inventor: WATCHAROTONE SUPINDA
IPC: A46D3/00
Filed: 2019-05-14
Abstract: A toothbrush comprises a handle; a head connected to the handle; and a plurality of bristles, respective ones of the plurality of bristles including a first end having a tapered first tip, a second end having a tapered second tip, and a substantially cylindrical shaft extending between the first end and the second end. Respective ones of the plurality of bristles are fastened to the head by a fastener at a fastening point along the shaft, the fastening point being located nearer to the second end than to the first end such that the first end extends from a surface of the head to a first height and the second end extends from the surface of the head to a second height. A difference between the first height and the second height is greater than or equal to 2.25 mm.
Patent CA-3044629-A1 (CA)
Title: Digitally animated greeting card
Inventor: MOORE TERENCE J
IPC: G09F9/30
Filed: 2019-05-29
Abstract: This invention refines on the standard greeting card. This digitally animated greeting card includes a LCD/LED digital screen that displays an animated theme for the user. It also includes a speaker that can play an audio musical tune that can be turned on or off. The user can cycle through more than one animated theme and choose which one they decide to display.     On the front top centre of the card will be a speaker that will play a audio musical tune that can be turned up or down by either button on the side of the card. On the left side of the card there are a total of four buttons. The first button on the top is the Power on/off button, next is the Volume Up button, then the Volume Down button, and last the Cycle Animation button. On the lowest part on the left side of the card is a slot for a battery power source. The back front side of the card has Memory Unit. Fig. 1 focuses on the front side view of the greeting card, showing all the buttons and components Fig. 2 is the greeting card closed looking at the side view Fig. 3 is a view of the inside of the greeting card Fig. 4 is the process of using the greeting card
Patent CA-3045098-A1 (CA)
Title: Compositions and methods for the induction of cd8+ t-cells
Inventor: HONDA KENYA
IPC: A61K39/116
Filed: 2017-12-22
Abstract: Provided herein are compositions and methods for the induction and/or proliferation of CD8+ T-cells. The disclosure also provides methods of treatment of diseases that can be treated by the induction and/or proliferation of CD8+ T-cells.
Patent CA-3045512-A1 (CA)
Inventor: SANGER GEORGE A
IPC: G06F17/00
Filed: 2017-12-04
Abstract: Systems and methods for capturing audio which can be used in applications such as virtual reality, augmented reality, and mixed reality systems. Some systems may include a plurality of distributed monitoring devices in an environment, each having a microphone and a location tracking unit. The system can capture audio signals while also capturing location tracking signals which indicate the locations of the monitoring devices over time during capture of the audio signals. The system can generate a representation of at least a portion of a sound wave field in the environment based on the audio signals and the location tracking signals. The system may also determine one or more acoustic properties of the environment based on the audio signals and the location tracking signals.
Patent CA-3046911-A1 (CA)
Title: Electronically-active cannabinoids
Inventor: WHYTE DOUGLAS A
IPC: A61K31/05
Filed: 2019-06-18
Abstract: An animal's nervous system consists of individual neural cells (neurons), support cells and support structures. Neurons are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the electrical signals at every step in between. Neurons communicate with each other and the outside world through a combination of electrical and chemical signals, both within and external to the neuron. The central hub or soma of a neuron is connected to other neurons via transmitting arms or extensions (axons) of the first neuron, and receiving arms or extensions (dendrites) of the second neuron. Signals to be transmitted from one neuron to another travel electrically from the central soma region of the neuron, inside the connected axon to the end of the axon. At the end of an axon, an axon terminal or interface junction exists connecting the axon of the first neuron to the dendrite of the second. The electrical signal, having passed from the first's axon to the second's dendrite, then continues electrically inside the dendrite to the central soma of the second neuron. Signals flow by electrical processes within the neutron including electrotonic motion potentials and concentration-gradient action motion potentials.
Patent CA-3048963-A1 (CA)
Inventor: PYLE APRIL D
IPC: A61K48/00
Filed: 2017-02-09
Abstract: The present disclosure provides a method of modifying a mutant dystrophin gene in the genome of a cell. The present disclosure further provides compositions and kits for modifying a mutant dystrophin gene in the genome of a cell.
Patent CA-3050788-A1 (CA)
Inventor: ZHAO TIAN
IPC: H02S50/10
Filed: 2019-07-30
Abstract: Provided are a method for photovoltaic module fault diagnosis, an edge calculation processing device and an inverter. Firstly, multiple module-level power electronic devices are controlled to perform IV scanning on photovoltaic modules connected to the module-level power electronic devices respectively and IV curves of the photovoltaic modules are obtained by the module-level power electronic devices respectively. Secondly, an IV curve satisfying a condition is selected from the IV curves of the photovoltaic modules as a reference curve. Thirdly, each of remaining IV curves in the IV curves of the photovoltaic modules other than the reference curve is compared with the reference curve, to generate comparison results. Finally, a fault diagnosis result for each of the photovoltaic modules is generated based on the comparison results.
Patent CA-3051652-A1 (CA)
Inventor: DELIENCOURT-GODEFROY GERALDINE
IPC: C07K5/09
Filed: 2017-01-30
Abstract: La présente invention concerne un composé de la formule suivante (I), ainsi qu'une composition pharmaceutique comprenant au moins un composé de la formule suivante (I) et au moins un excipient pharmaceutiquement acceptable, destinée à être utilisée le traitement et/ou la prévention et/ou l'atténuation de maladies de fibrose, en particulier des cicatrices excessives telles que des chéloïdes ou des cicatrices hypertrophiques.
Patent CA-3056162-A1 (CA)
Inventor: XIN YU
IPC: H04W28/20
Filed: 2017-10-19
Abstract: Disclosed is a transmission bandwidth configuration method, comprising: configuring a first channel bandwidth (CB) of a carrier; and when the first CB is greater than a first preset bandwidth, configuring a sub-carrier in first transmission bandwidth configuration (TBC) according to a preset percentage X of the first TBC in the first CB and the first CB, thereby completing sub-carrier configuration in the TBC, wherein the preset percentage X is within a range of [a preset lower limiting value, a preset upper limiting value], the preset lower limiting value is greater than 90%, and the preset upper limiting value is lower than 100%. Also disclosed is a transmission node.