baber/WOPTO huggingface dataset:
Patent NZ-337207-A (NZ)
Title: A method to identify plant proteins that function in G-protein coupled systems and compositions therefor
Inventor: SAROKIN LAURA PATRICIA
IPC: G01N33/566
Filed: 1998-02-13
Abstract: A method of identifying a plant protein that is suspected of functioning as or similar to a G protein subunit or complex in a G-protein coupled cellular signaling system comprising the steps of: a) providing a host cell with a nucleotide sequence encoding the target plant protein it is desired to identify b) rendering inoperative all or a portion of an endogenous component of a G protein subunit complex present in the host cell and suspected of being a corollary to the target plant protein c) allowing the host cell to grow d) measuring the growth as an indication that the plant protein it is desired to identify is functioning in said host cell, in the absence of functional expression of the corollary endogenous component of the G protein coupled cellular signaling pathway in said host cell.  Preferably the endogenous component of step b) is a Gá, Gâ or Gã subunit or a Gâã complex and the plant protein it is desired to identify comprises a Gá, Gâ or Gã-like protein or a Gâã-like complex.
Patent NZ-501914-A (NZ)
Title: Crystalline 11-(4-[2-(2-hydroxyethyl)ethyl]-1-piperazinyl)-di-benzo[b,f][1,4]thiazepine useful as an antipsychotic agent
Inventor: SNAPE EVAN WILLIAM
IPC: A61K31/55
Filed: 1998-07-28
Abstract: The compound crystalline 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)-di-benzo[b,f][1,4]thiazepine is disclosed.  A pharmaceutical composition thereof is useful for treating neuropsychiatric disorders.
Patent NZ-504249-A (NZ)
Title: Ear ring with a keeper and ornamental portion wherein the keeper passes through the ear lobe and is rotated to sit on the peripheral side of the ear
Inventor: ROYCROFT HEATHER ELIZABETH HEL
IPC: A44C7/00
Filed: 2000-05-02
Abstract: An ear ornament (10) to be worn on a pierced ear. The ornament is characterised by an elongated ornament (11) and keeper component (13) fixably joined by a web portion adapted to locate in a hole in an ear. The keeper component is of thickness such that a free end thereof is passed through the hole until the web portion (14) enters the hole, whereupon the keeper component is manipulated to extend from the hole and lie behind the peripheral ridge of the ear at thee back of the ear.
Patent NZ-506246-A (NZ)
Title: Sesquiterpene synthases from grand fir abies grandies, and methods of use
Inventor: CROTEAU RODNEY B
IPC: C12N9/88
Filed: 1999-01-21
Abstract: An isolated nucleic acid molecule, encoding a sesquiterpene synthase, that hybridizes in 0.5 SSC at 55oC to the complement of any of SEQ ID NO:12, SEQ ID NO:19 or SEQ ID NO:23 as set forth in the specification.  Also included is the protein encoded by the nucleic acid, expression vectors comprising the nucleic acid, methods of expression in a non-human host and plants comprising the vector.
Patent NZ-509534-A (NZ)
Title: Mounting of flexible display panels
Inventor: LOWNDES JAMES GEORGE
IPC: G09F/
Filed: 1999-05-17
Abstract: A display panel (10) is mounted on an underlying surface (TSW) using three extrusions (20.1, 36.1 and 20.3). The extrusions (20.1, 36.1) are secured to the underlying surface in parallel but spaced positions. The panel (10) has stiffening elements (18) in pockets (16) along its edges. The elements and pockets are inserted into a recess (26) of the upper extrusion (20.1) and into a recess (26) of the lower extrusion (20.3). With the extrusion (20.3) lying along the line (L) its end (34) is inserted in the recess (44) of the extrusion (36.1). The extrusion (20.3) is then swung in an arc (arrow A) against the surface (TSW) to tension the panel (10). The extrusion (20.3) is then fixed to the surface (TSW).
Patent NZ-512006-A (NZ)
Title: Medical treatment with human TNF-alpha antibodies
Inventor: SALFELD JOCHEN G
IPC: A61P9/00
Filed: 1997-02-10
Abstract: Human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor alpha (hTNF alpha ) are disclosed. These antibodies have high affinity for hTNF alpha (e.g., Kd = 10-8 M or less), a slow off rate for hTNF alpha dissociation (e.g., Koff = 10<-3>sec<-1> or less) and neutralize hTNF alpha activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hTNF alpha and for inhibiting hTNF alpha activity, e.g., in a human subject suffering from a disorder in which hTNF alpha activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. Particular diseases include malaria, meningitis, cachexia, acquired immune deficiency syndrome (AIDS), bacterial meningitis AIDS-related complex, cytomegalovirus infection secondary to transplantation, fever and myalgias due to infection (such as influenza), cachexia secondary to infection (e.g., secondary to AIDS or ARC), adult respiratory distress syndrome, shock lung, chronic pulmonary inflammatory disease, pulmonary sarcoidosis, pulmonary fibrosis, silicosis, inflammatory bowel disorders, idiopathic inflammatory bowel disease, (which includes two syndromes, Crohn's disease and ulcerative colitis), ischemia of the heart, heart insufficiency, septic shock, endotoxic shock, gram negative sepsis and toxic shock syndrome.
Patent NZ-519382-A (NZ)
Title: Mixer valve with a single lever operation for fluid flow
Inventor: ATWILL RAYMOND STEWART
IPC: F16K11/076
Filed: 2000-11-06
Abstract: A single lever operated mixer valve is provided in which a valve member has a section shaped as part of a surface of a solid of revolution. The section allows arcuate movement in two planes of the valve member when it is fitted in a housing. An inner surface of the housing is of a shape complementary to the surface of said section. The movement of the valve member can be in two planes and is under the control of a single lever. The section has inlet port means for two liquids to be mixed. The inlet port means can include passageways extending from the surface of the section to a mixing region of the housing formed either on the opposite side of the valve member to the section or within the valve member. The passageways can be directed to form a substantially undeviated flow of the liquids from the inlet port means to the mixing region and to an outlet of the housing and mixer valve.
Patent NZ-519650-A (NZ)
Title: Apparatus for debarking logs or for preparing logs for debarking
Inventor: HANNIMAKI ARI
IPC: B27L1/02
Filed: 2000-12-15
Abstract: The invention relates to an apparatus for debarking logs (1) or preparing logs for separately performed debarking - especially logs that are difficult to debark - the apparatus comprising a drum (3) rotating about its central axis, through the space limited by the cylindrical inner sleeve (4) of which drum the logs (1) to be treated are fed, whereby the logs are subjected to abrasion and impact blows in order to treat the bark. Inside the drum (3) is formed an inner member (5), which member is arranged to divide the space limited by the cylindrical inner sleeve (4) of the drum (3) into a treatment space (6) proper and a space (7) remaining outside of it, whereby the logs (1) fed through the drum (3) are arranged to travel through the drum (3) via the said treatment space (6).
Patent NZ-520023-A (NZ)
Title: Aniline-derived ligands for the thyroid receptor
Inventor: FRIENDS TODD JASON
IPC: A61K31/22
Filed: 2001-01-12
Abstract: Thyroid receptor ligands are provided which have the general formula (I) in which X is -O-, -S-, -CH2-, -CO-, or -NH-; Y is -(CH2)n- where n is an integer from 1 to 5, or cis- or trans-ethylene; R1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or different and are hydrogen, halogen, alkyl of 1 to 4 carbons or cycloalkyl of 3 to 6 carbons, at least one of R2 and R3 being other than hydrogen; R4 is hydrogen or lower alkyl; R5 is hydrogen or lower alkyl; R6 is carboxylic acid, or esters or prodrugs; R7 is hydrogen or an alkanoyl or an aroyl. In addition, a method is provided for preventing, inhibiting or treating a disease associated with metabolism dysfunction or which is dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount. Examples of such diseases associated with metabolism dysfunction or are dependent upon the expression of a T3 regulated gene include obesity, hypercholesterolemia, atherosclerosis, cardiac arrhythmias, depression, osteoporosis, hypothyroidism, goiter, thyroid cancer as well as glaucoma, congestive heart failure and skin disorders.
Patent NZ-522847-A (NZ)
Title: Methods for refolding proteins containing free cysteine residues
Inventor: ROSENDAHL MARY S
IPC: C07K14/52
Filed: 2001-05-16
Abstract: A method for preparing a refolded, soluble form of an insoluble or aggregated protein that is a member of the Growth Hormone Supergene family and which has one or more free cysteines. An isolated host cell expressing this protein is lysed and the insoluble or aggregated protein is exposed to a denaturing agent, a reducing agent and a cysteine blocking agent to stabilize and reduce the protein. It is then refolded by reducing the concentrations of the denaturing and reducing agents. The soluble, refolded proteins produced by the novel methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form PEGylated proteins.
Patent NZ-523078-A (NZ)
Title: Silica coated nanoparticles and their use for identifying cells
Inventor: TAN WEIHONG
IPC: G01N33/552
Filed: 2001-05-14
Abstract: A plurality of nanoparticles have a mean size of less than 1 micron each of the nanoparticles comprising a core and a silica shell enveloping the core. Preferably the core comprises a dye selected from Ru/Bpy and Eu/Bpy, a pigment that is an inorganic salt selected from potassium permanganate, potassium dichromate, nickel sulfate, cobalt chloride, iron(III) chloride and copper nitrate, metal selected from Ag or Cd, is magnetic and selected from magnetite, maghemite and greigite. The shell may be derivatised with a functional preferably selected from a protein that is an antibody, a nucleic acid, biotin or streptavidin. Also described is a method of making coated particles via microemulsion and a method of identifying cells expressing a preselected molecule comprising the steps of providing a plurality of cells at least some of which express the preselected molecule, providing a plurality of silica-coated nanoparticles coated with a functional group that binds to the preselected molecule, mixing the nanoparticles with the cells to a form a mixture and then placing the mixture under conditions that allow the nanoparticles to bind cells expressing the preselected molecule; and then analyzing the cells for bound nanoparticles.
Patent NZ-523664-A (NZ)
Title: Derivatives of branched-chain lipophilic molecules and uses thereof
Inventor: KOZAK ALEXANDER
IPC: A61P31/04
Filed: 2001-08-01
Abstract: Phospho-derivatives of branched-chain lipophilic molecules and pharmaceutical compositions comprising these molecules that are useful for permeabilizing biological barriers and for inhibiting tumor growth are disclosed.
Patent NZ-526994-A (NZ)
Title: Novel modified released formulation
Inventor: JUPPO ANNE
IPC: A61K9/22
Filed: 2002-02-08
Abstract: A multiparticulate, modified release solid dispersion formulation, comprising (i) an active drug substance having a mater-solubility of, or below, 8 mg/ml at room temperature; (ii) at least one hydrophobic matrix former which is meltable, non-swelling amphiphilic lipid having a water solubility below 1 mg/g; and (iii) at least on hydrophilic matrix former which is a meltable excipient having a water-solubility above 0.1g/g; wherein the weight ration hydrophobic matrix former/hydrophilic matrix former is e" 1; and the particle size is less tan 300ìm; and the use of said formulation for the manufacture of a medicament for the treatment of cardiovascular disease or cancer therapy.
Patent NZ-528350-A (NZ)
Title: A vaccine-induced hepatitis B viral strain and uses thereof
Inventor: OON CHONG JIN
IPC: C12N7/01
Filed: 1998-06-19
Abstract: Disclosed is a method of obtaining antibodies to a polypeptide which is a mutant major surface antigen of a strain of hepatitis B virus, which differ from the amino acid sequence of a major surface antigen of a wildtype hepatitis B virus in that the amino acid at position number 145 of such polypeptide is an arginine, rather than a glycine, and not to the major surface antigen of a wildtype hepatitis B virus, comprising: (a) obtaining the polypeptide in a purified form; (b) immunizing a nonùhuman organism capable of producing antibodies against the purified polypeptide; (c) collecting the produced antibodies; (d) combining the produced antibodies and the purified polypeptide under conditions to form a complex; and (e) determining which produced antibodies form a complex with the purified polypeptide so as to obtain antibodies to the polypeptide. Such polypeptides are useful for determining whether a subject is infected with a strain of hepatitis B virus designated Human Hepatitis B Virus Surface Antigen-æSÆ-145 Singapore strain (glycine to arginine). (62) Divided out of 508892
Patent NZ-534042-A (NZ)
Title: Process for producing snack, snack and snack-like food
Inventor: TAKEO HIDEKI
IPC: A23L1/164
Filed: 2003-10-15
Abstract: It is intended to provide a process for producing a snack whereby a snack food made of bread which having a texture close to potato chips can be obtained. A crust-less bread slice (1) of 1 mm or more in thickness, which has been toasted into brown, is subjected to a heat treatment under elevated pressure by using a press (2). When the moisture content of the bread (1) amounts to about 30% by mass, the bread (1) is taken out from the press (2) and hot air-dried until the moisture content thereof is lowered to about 5% by mass. Thus, a processed bread product having a curled edge (an unseasoned snack) can be obtained.
Patent NZ-538030-A (NZ)
Title: Formulation of human antibodies for treating TNF-alpha associated disorders
Inventor: KRAUSE HANS-JUERGEN
IPC: A61K9/19
Filed: 2003-08-15
Abstract: A liquid aqueous pharmaceutical formulation with a pH between 4-8 which contains a high protein concentration, including an antibody concentration ranging from 20-130mg/ml and has a shelf life of at least 18 months. The formulation can be used in the manufacture of a medicament to treat a disorder in which TNF alpha activity is detrimental.
Patent NZ-538523-A (NZ)
Title: Grid canvas where objects are placed onto the grid for use in computer graphics
Inventor: TITOV DMITRY G
IPC: G06T11/60
Filed: 2005-02-28
Abstract: In a computer system having a graphical user interface and a display, a method of generating a grid canvas the method of generating a grid canvas, comprises defining a grid; receiving an object definition signal with respect to the grid; defining a plurality of rows and columns on the grid; and displaying the object on the grid. The rows and columns are resizable and the grid has a bi-directional relationship with the object. The bi-directional relationship between objects and grid is such that moving one (gridline or object) will affect the other (object or gridline). In other words, expanding/collapsing the object will push the gridlines, and moving the gridline will expand/collapse the object.
Patent NZ-539065-A (NZ)
Title: Borehole conductivity profiler
Inventor: KELLER CARL E
IPC: E21B47/10
Filed: 2003-10-08
Abstract: A method of using an everting borehole liner to perform fluid conductivity measurements in materials surrounding a pipe, tube, or conduit, such as a borehole below the surface of the Earth. A flexible liner is everted (turned inside out) into the borehole with an internal pressurized fluid. As the liner displaces the ambient fluid in the borehole into the surrounding formation, the rate of descent of the liner is recorded. As the impermeable liner covers the flow paths in the wall of the hole, the descent rate slows. From the measured descent rate, the flow rates out discrete sections of the borehole are determined.
Patent NZ-542746-A (NZ)
Title: Respirator with enclosing hood and control of fan in response to a measured flow of by-passed portion of airflow
Inventor: CHURCH COLIN
IPC: A42B3/22
Filed: 2004-03-29
Abstract: Fan 26 forces air through a filter having pleated glass fibre papers 30 and through a hood having shell 12. A portion of the air flows through a by-pass conduit 44 and to air sensor 46. Fan speed is controlled from the sensed air flow so as to provide a constant air flow rate.
Patent NZ-545247-A (NZ)
Title: Method and apparatus for assessing or predicting the characteristics of wood
Inventor: HARRIS PAUL DAVID
Filed: 2006-02-09
Abstract: A method for determining characteristics of a portion of a wood specimen is disclosed. An acoustic signal (2) is produced part way along the length of the specimen. A response, including a reverberation (7) from a first end (6) of the specimen, is sensed part way along the length of the specimen. The characteristics of the portion of interest are determined based on analysis of the sensed response.
Patent NZ-548634-A (NZ)
Title: Tree stump grinder having teeth which include a slot in the tooth body that engages a slot in a rotor of a grinding wheel of the tree stump grinder
Inventor: WATTS PATRICK
IPC: A01G23/06
Filed: 2005-02-11
Abstract: A tooth for use in a grinding wheel having a rotor, and a grinding unit that uses the tooth, is disclosed. The tooth comprises a main body where the body has a slot defined by two substantially planar surfaces for, in use, engaging with a slot in the rotor. The cutting face includes at least two tips which are perpendicular to each other. At least one cutting face is connected to, and extends away from, the main body. In use, the force in the plane of the rotor is transferred onto the rotor via one of the planar surfaces provided on the slot.
Patent NZ-562455-A (NZ)
Title: Method for determining pre-remission phase of ulcerative colitis using PGE-MUM and reagent kit for the same
Inventor: FUJIWARA MUTSUNORI
IPC: G01N33/493
Filed: 2006-04-14
Abstract: Disclosed is a method for judging stages between a pre-remission phase and a remission phase of ulcerative colitis comprising the steps of: setting as a base value a value of a main metabolite of prostaglandin (PGE-MUM) concentration in urine obtained by measuring PGE-MUM contained in the urine of patients diagnosed as being in the remission phase of ulcerative colitis, said remission having been induced by the administration of anti-inflammatory drugs; and judging that ulcerative colitis is in the pre-remission phase when the value of PGE-MUM concentration in urine of the patients is in a range exceeding the base value and being not more than 3 times the base value, and that ulcerative colitis is in the remission phase when the value of PGE-MUM concentration in urine of the patients is in a range of not more than the base value.
Patent NZ-566263-A (NZ)
Title: CCR9 inhibitors and methods of use thereof
Inventor: FLEMING PAUL
IPC: C07C311/15
Filed: 2003-05-21
Abstract: Disclosed is a compound of formula I or a pharmaceutically acceptable salt thereof wherein Y is C=O, S(O) or S(O)2; one of X1, X2, or X3 is N and the other two are CR; and wherein the rest of the substituents are disclosed within the specification. Also disclosed is the use of an effective amount of a compound of any one of claims 1-19 for the production of a medicament for treating an inflammatory bowel disease (IBD) in a subject in need thereof.
Patent NZ-566841-A (NZ)
Title: Rocker spring assembly
Inventor: LAPOINTE LARRY P
IPC: F16F1/04
Filed: 2006-10-02
Abstract: A rocker spring assembly 26 for a rocking chair couples the chair frame operable for rocking motion relative to a stationary base to the base. The rocker spring assembly includes upper and lower brackets 36 connectable respectively to the base and the chair frame and a single coil spring 56 connected to both brackets. A single displacement limiting device 58 is housed within the coil spring and includes a shaft 58 having a bulbous head 46, 48 at opposed ends, the shaft being movably received within an aperture in each of the brackets, so that the total displacement between the first and second brackets is limited by the bulbous heads contacting the first and second brackets.
Patent NZ-569836-A (NZ)
Title: Novel compounds
Inventor: WISNIEWSKI KAZIMIERZ
IPC: C07K2/00
Filed: 2007-02-05
Abstract: Disclosed are compounds are represented by the general formula (I), as further defined in the specification. The compounds and pharmaceutical compositions comprising them are useful for the manufacture of a medicament for treatment of shock of hypovolemic or vasodilatory origin, bleeding oesophageal varices, hepatorenal syndrome, cardiopulmonary resuscitation, anaesthesia-induced hypotension, orthostatic hypotension, paracentesis-induced circulatory dysfunction, intra-operative blood loss or blood loss associated with burn debridement and epistaxis, and of various ocular diseases by increasing lacrimation/tear formation.
Patent NZ-575008-A (NZ)
Title: Shear plate with portion having apertures to receieve ends of internally threaded ferrules and another portion inclined away, for closer placement to concrete edge
Inventor: CONNELL ROBERT URQUHART
IPC: E04B1/21
Filed: 2007-08-29
Abstract: A shear plate for application to the outer end portion of a ferrule to be cast into a concrete component such as a wall panel, the shear plate having an outer portion engageable with the ferrule and, beyond the outer portion, a portion shaped to incline away from the adjacent surface of the concrete component to which the outer end of the ferrule is to be exposed. The shear plate enables the ferrule to be situated close to an edge of the component in a situation in which it will be subjected to shear loading in a direction towards that edge.
Patent NZ-575521-A (NZ)
Title: Use of 2-6-(3-amino-piperidin-l-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl-4-fluoro-benzonitrile
Inventor: CHRISTOPHER RONALD J
IPC: A61P31/18
Filed: 2007-09-11
Abstract: Disclosed is the use of 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2Hpyrimidin-1-ylmethyl]-4-fluoro-benzonitrile (as pictured) in the production of a medicament for the treatment of diabetes, wherein the medicament is adapted to be administered at a weekly dose of between 1 mg and 250 mg once per week.
Patent NZ-584739-A (NZ)
Title: Simultaneous detection of tandem repeats in target polynucleotides at a given polymorphic locus
Inventor: GALE NITTAYA
IPC: C12Q1/68
Filed: 2008-10-21
Abstract: Disclosed is a method for determining the number of tandem repeats in a target polynucleotide, the method comprising (a) providing a sample containing the target polynucleotide, wherein one or more of the tandem repeats in the target polynucleotide is in single stranded form, (b) hybridising a labelled probe oligonucleotide to the single stranded portion of the target polynucleotide, wherein the probe oligonucleotide is complementary to at least one of the tandem repeats, and at least 5 nucleotides of the probe oligonucleotide are complementary to the tandem repeats, in the single stranded portion of the target polynucleotide, and (c) determining the number of tandem repeats in the target polynucleotide based on the hybridisation of the probe oligonucleotide to the single stranded portion of the target polynucleotide.