baber/WOPTO huggingface dataset:
Patent WO-2021026470-A1 (WO)
Inventor: SENNESS CHARLES
IPC: A61B18/18
Filed: 2020-08-07
Abstract: The disclosure provides a cooling system for a surgical ablation device, the device having a cooling circuit comprising a device coolant supply line having a supply coupling; a coolant return line having a return coupling; coolant passageways within the device to circulate coolant within the device, the supply line and the return line being in fluid communication via the device coolant passageway(s); a coolant manifold configured to fluidly connect a cooling fluid source to at least one manifold fluid outlet port, such as to place the cooling fluid source in fluid communication with the one or more device coolant passageways. wherein the supply coupling is configured for connection to a manifold outlet port of the manifold.
Patent WO-2021030768-A1 (WO)
Title: Vésicules extracellulaires avec des oligonucléotides antisens stat3
Inventor: BOUTIN ADAM
IPC: A61K9/127
Filed: 2020-08-14
Abstract: La présente invention concerne des vésicules extracellulaires modifiées, par exemple des exosomes, comprenant un oligonucléotide antisens (ASO), qui est capable de réduire et/ou d'inhiber l'expression de l'ARNm de STAT3 et/ou de la protéine STAT3. L'invention concerne également des ASO qui peuvent être utilisés avec les vésicules extracellulaires modifiées. La présente invention concerne également des procédés d'utilisation des exosomes et d'ASO pour traiter et/ou prévenir des maladies, telles que le cancer.
Patent WO-2021247062-A1 (WO)
Inventor: AL-SALEH SALAH HAMAD
IPC: G01N13/02
Filed: 2020-09-01
Abstract: A method for determining interfacial tension of a hydrocarbon in a brine fluid, the method including injecting a first brine fluid into a test cell, the first brine fluid having an initial ionic composition, injecting a hydrocarbon fluid into the test cell, contacting the hydrocarbon fluid with the first brine fluid, forming a droplet, measuring the interfacial tension of the hydrocarbon fluid in contact with the first brine fluid, at least partially displacing the first brine fluid with an inert gas, measuring a ionic composition salinity of the displaced first brine fluid in an ionic chromatograph, and comparing the measured ionic composition salinity to the initial ionic composition.
Patent WO-2021046069-A1 (WO)
Title: Graphene-based elastic heat spreader films
Inventor: LIN YI-JUN
IPC: C08J5/18
Filed: 2020-09-02
Abstract: Provided is a elastic heat spreader film (and production process for manufacturing same) comprising: (a) an elastomer or rubber as a binder material or a matrix material; and (b) multiple graphene sheets that are bonded by the binder material or dispersed in the matrix material, wherein the multiple graphene sheets are substantially aligned to be parallel to one another and wherein the elastomer or rubber is in an amount from 0.001% to 20% by weight based on the total heat spreader film weight; wherein the multiple graphene sheets contain single-layer or few-layer graphene sheets selected from pristine graphene, graphene oxide, reduced graphene oxide, graphene fluoride, graphene chloride, graphene bromide, graphene iodide, hydrogenated graphene, nitrogenated graphene, doped graphene, chemically functionalized graphene, or a combination thereof; and wherein the elastic heat spreader film has a fully recoverable tensile elastic strain from 2% to 100% and an in-plane thermal conductivity from 200 W/mK to 1,750 W/mK.
Patent WO-2021046165-A1 (WO)
Title: Cesium-deficient cesium phosphates for proton conducting electrolytes
Inventor: WANG LOUIS S
IPC: H01M8/1016
Filed: 2020-09-03
Abstract: Proton conducting materials and membranes and electrochemical devices incorporating the materials and membranes are provided. Also provided are methods of making the materials and membranes and methods of operating the electrochemical devices. The proton conducting materials are solid acids that form superprotonic phases at elevated temperatures. The superprotonic phases have a cubic structure and the general formula: M (1-x) H y ]H 2 PO 4 , where M represents one or more monovalent cations or a combination of monovalent cations and divalent cations, 0 < x ≤ 2/9, and y is a number that provides charge balancing.
Patent WO-2021050580-A1 (WO)
Title: Crystalline form of a multi-tyrosine kinase inhibitor, method of preparation, and use thereof
Inventor: RAEPPEL FRANCK
IPC: A61K31/444
Filed: 2020-09-09
Abstract: The present invention relates to crystalline forms of N-(3 -fluoro-4-((2-(5-(((2- methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-N-(4- fluorophenyl)cyclopropane- 1,1 -di carboxamide (Compound 1), pharmaceutical compositions comprising the crystalline form, processes for preparing the crystalline form and methods of use therefore.
Patent WO-2021055938-A1 (WO)
Title: Suture materials, suture placement devices and methods of suture placement and tissue approximation
Inventor: CHALEKSON CHARLES P
IPC: A61B17/00
Filed: 2020-09-21
Abstract: The present invention includes a suture adapted to be anchored into tissue, the suture comprising a length of an elongate flexible suture material and a plurality of barbed anchor articles slidingly disposed along a length of the suture material. The invention also includes a suture placement device designed to insert the anchors of the suture articles into opposing tissue surfaces and associated methods for approximating and/or affixing opposed tissue surfaces in surgical procedures and the like.
Patent WO-2021061685-A1 (WO)
Inventor: HARDING DAVID
IPC: A61F2/44
Filed: 2020-09-23
Abstract: An extraction tool useful for removing an installed artificial disc from a spine is provided. The extraction tool is inserted between the installed artificial disc and an upper vertebra and a lower vertebrae and engages the artificial disc to allow a surgeon to remove the artificial disc from the spine.
Patent WO-2021067415-A1 (WO)
Inventor: BANDARA ALOKA B
IPC: C12N15/85
Filed: 2020-09-30
Abstract: La présente invention concerne une lignée de cellules humaines recombinante qui n'exprime pas la protéine fer-soufre 2 NADH déshydrogénase [ubiquinone] (NDUFS2) endogène fonctionnelle. Cette lignée cellulaire knock-out peut être utilisée pour faire avancer la compréhension basique de la sous-unité protéique NDUFS2 dans l'assemblage et la fonction globale du complexe I. En outre, cette lignée cellulaire peut être utilisée pour tester des agents thérapeutiques pour fixer ou contourner le complexe I dysfonctionnel.
Patent WO-2021097434-A1 (WO)
Title: Fibroblast therapy for inflammatory bowel disease
Inventor: O'HEERON PETE
IPC: A61K38/18
Filed: 2020-11-16
Abstract: In some aspects, disclosed herein are methods and compositions for treatment of inflammatory bowel disease using fibroblasts or derivatives thereof. Disclosed herein are compositions having tolerogenic properties. Compositions of the present disclosure include fibroblasts, activated fibroblasts, fibroblast apoptotic bodies, and fibroblast exosomes. Methods of the present disclosure include, in some cases, providing fibroblasts or derivatives thereof to a subject to treat an inflammatory bowel disease. In some cases, dendritic cells are cultured with fibroblasts and provided to a subject to treat an inflammatory bowel disease.
Patent WO-2021102388-A1 (WO)
Inventor: AULD JACK
IPC: A61F9/00
Filed: 2020-11-21
Abstract: Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes an injector cannula having a soft injector tip. A retractable tip protector tube is slidably disposed on the flow cannula between an extended position in which the tip protector tube covers the entire injector tip, and a retracted position in which the tip protector tube is retracted proximally thereby exposing at least part of the injector tip. Accordingly, the tip protector tube protects the injector tip from being damaged while advancing the injector tip to a target injection site.
Patent WO-2021118842-A1 (WO)
Inventor: O'BRIEN TOM
IPC: G01V1/18
Filed: 2020-12-02
Abstract: Systems, apparatuses, and method of measuring hydrophone impedance are provided herein. A sensor can convert an acoustic wave received via a liquid medium into an electric signal. A signal encoder (402) is coupled with the sensor (300) to receive the electric signal. A test signal generator (406) is coupled in series with the sensor and the signal encoder and can generate a test signal. The test signal can measure an impedance of the sensor. A switch component (410) is coupled in series with the sensor, the signal encoder, and the test signal generator. The switch component can route the test signal to a first terminal of the sensor and through a second terminal of sensor during a first operational state. The switch component can route the test signal to the second terminal of the sensor and through the first terminal of sensor during a second operational state.
Patent WO-2021126900-A1 (WO)
Title: Fluid component body with leak test passages
Inventor: GLIME WILLIAM
IPC: F16K37/00
Filed: 2020-12-16
Abstract: A manifold body includes at least first and second valve body segments each comprising an upper perimeter wall portion defining a valve cavity and a lower base portion defining one or more flow ports, a unified leak test port, a first branch leak test passage extending from the unified leak test port to an outer peripheral portion of the valve cavity of the first valve body segment, radially outward of an outer seal surface in the valve cavity, and a second branch leak test passage extending from the unified leak test port to an outer peripheral portion of the valve cavity of the second valve body segment, radially outward of an outer seal surface in the valve cavity.
Patent WO-2021141824-A1 (WO)
Title: Spectrum management for coexistence of heterogeneous wireless technologies
Inventor: KULKARNI SANTOSH
IPC: H04W16/14
Filed: 2020-12-31
Abstract: Spectrum management for coexistence of heterogeneous wireless technologies may be provided. A first Radio Frequency (RF) event metric may be received from a first service end point. The first RF event metric may comprise a time a first event occurred. A second RF event metric may be received from a second service end point. The second RF event metric may comprise a time a second event occurred. Then it may be determined that the time the first event occurred and the time the second event occurred are substantially congruent. Next, in response to determining that the time the first event occurred and the time the second event occurred are substantially congruent, the first service end point and the second service end point may be grouped in a first RF group thereby allowing frequency re-use across similar RF groups. Then different channels may be assigned to the first service end point and the second service end point.
Patent WO-2021142158-A1 (WO)
Title: Dhcp snooping with host mobility
Inventor: PANDEY MANOJ
IPC: H04L29/12
Filed: 2021-01-07
Abstract: .This disclosure describes methods of operating a leaf node device, such as a switch device, connected to a switch fabric of a network. The leaf node device receives, from another leaf node device via the switch fabric, an indication of a secure route to a host device. In response to receiving the indication of the secure route, the leaf node device creates or updates a routing entry for the host device in a routing information base of the leaf node device and creates or updates an entry for the host device in a Dynamic Host Configuration Protocol (DHCP) snoop database of the leaf node device. The leaf node may thereby communicate with the host device that is attached to the leaf node device as a result of moving from the other leaf node device.
Patent WO-2021146217-A1 (WO)
Title: Extraction filter basket
Inventor: DALL'AGLIO SAURO
IPC: A47J31/06
Filed: 2021-01-12
Abstract: A filter basket for a beverage machine includes a sidewall and a strainer portion. The filter basket forms a brew chamber into which ground coffee or other products are added. The brew chamber is defined by a sidewall, a strainer surface, and a smooth contour between the tapered sidewall and the strainer surface. The brew chamber is defined by smooth lines to create better fluid flow through the extraction process. A plurality of apertures are formed in the strainer surface to filter out large particles while allowing brewed beverage to flow therethrough. The tapered sidewalls in combination with the strainer surface, the smooth contour, and the unique pozzetto shape, result in a pressure profile and fluid flow characteristics that reduce the tendency of channeling through the ground coffee and result in a more consistent and uniform extraction.
Patent WO-2021154607-A1 (WO)
Title: Method and apparatus for adaptive indirect carrier modulation
Inventor: HAQUE TANBIR
IPC: H04L27/00
Filed: 2021-01-22
Abstract: A wireless transmit / receive unit, WTRU, can select a constellation from a set of constellations corresponding to a symbol configuration for indirect carrier modulation, ICM, based on at least one constellation performance efficacy indicator, each constellation performance efficacy indicator respectively corresponding to a constellation of the set of constellations, and use the selected constellation and symbol configuration to simultaneously harvest energy and transmit data.
Patent WO-2021163128-A1 (WO)
Title: Vehicle pedal including redundant dual output inductive position sensor with reduced coupling coil circuits
Inventor: MILLER TAD L
IPC: G01D5/20
Filed: 2021-02-10
Abstract: A vehicle pedal assembly comprising a pedal housing, a rotatable pedal, and an inductive position sensor. The inductive position sensor includes an inductive sensor target rotatable in response to the rotation of the pedal and a substrate positioned opposite the inductive sensor target. First and second redundant inductive transmit and receiver coil circuits are defined and located on different sections of the substrate in a relationship with the respective receiver coil circuits of the first and second transmit and receiver coil circuits at least partially surrounded by the respective transmit coil circuits of the first and second transmit and receiver coil circuits for reducing the coupling factor between the first and second transmit and receiver coil circuits.
Patent WO-2021178326-A1 (WO)
Inventor: LINSKY JOEL
IPC: H04L1/00
Filed: 2021-03-01
Abstract: A wireless device is provided that determines a set of expected packets from a second wireless device, each expected packet of the set of expected packets comprising an expected cyclic redundancy check (CRC) of a set of expected CRCs, receives a packet from the second wireless device, the received packet comprising a header and a first CRC, determines whether a second CRC generated based on the header in the received packet matches the first CRC received in the received packet, determines, when the generated second CRC does not match the first CRC received in the received packet, a third CRC of the set of expected CRCs based on the first CRC, and replaces the received header with a header corresponding to the determined third CRC.
Patent WO-2022093305-A1 (WO)
Title: Systems and methods for self-learning artificial intelligence of things (aiot) devices and services
Inventor: STUBBS MARK
IPC: G06N5/04
Filed: 2021-03-02
Abstract: The invention is generally directed to systems and methods of monitoring or predicting a service event for an industrial asset using an artificial intelligence of things (AIoT) system including an AIoT device, AIoT cloud, and a self-learning AI classification and analytics engine. The device may include one or more sensors and an inference engine for reducing power consumption and detecting anomalies at the edge and sending data associated with anomalies to a signal processor for classification and AI-driven automatic configuration. Classification may be based on narrow- band analysis and/or machine learning models. If an anomaly is detected power may be provided to a communication module to send sensor data to the signal processor for classification and/or further processing. Classifications or determinations made by the signal processor or detected through a work-order system may be used to automatically retrain the inference model on the edge, so that the system is self-learning.
Patent WO-2021183367-A1 (WO)
Title: Laser pulse shaping to enhance conversion efficiency and protect fiber optic delivery system for disruption of vascular calcium
Inventor: MASSIMINI DANIEL
IPC: A61B18/26
Filed: 2021-03-04
Abstract: A catheter system (100) includes a power source (124), a controller (123), and a light guide (122). The power source (124) generates a plurality of energy pulses (242B, 342B). The controller (123) controls the power source (124) so that the plurality of energy pulses (242B, 342A-B) cooperate to produce a composite energy pulse (348A-B, 448A-C, 548A-F) having a composite pulse shape. The light guide (122) receives the composite energy pulse (348A-B, 448A-C, 548A-F). The light guide (122) emits light energy in a direction away from the light guide (122) to generate a plasma pulse (246A-B, 346A-B) away from the light guide (122). The power source (124) can be a laser and the light guide (122) can be an optical fiber. Each of the energy pulses (242B, 342A-B) has a pulse width, and the energy pulses (242B, 342A-B) are added to one another so that the composite energy pulse (348A-B, 448A-C, 548A-F) has a pulse width that is longer than the pulse width of any one of the energy pulses (242B, 342A-B). At least two of the energy pulses (242B, 342A-B) can have the same wavelength as or a different wavelength from one another.
Patent WO-2021178722-A1 (WO)
Inventor: KARAMANIS GEORGIOS
IPC: F28F3/02
Filed: 2021-03-04
Abstract: Thermal management devices, systems, and methods of fabrication thereof are generally directed to accommodating variability in height, shape, or other geometric features of one or more heat-dissipating components on a substrate while maintaining efficient transfer of heat away from the one or more heat-dissipating components. For example, a thermal management device may include a housing, a diaphragm, and a wick, the wick disposed along a chamber defined by the housing and the diaphragm such that a fluid within the chamber may evaporate and condense along the chamber to transfer heat away from one or more heat-dissipating components (e.g., electronic components or photonics). The diaphragm may be resiliently flexible relative to the housing to bias a contact surface of the diaphragm against one or more heat-dissipating components while maintaining efficient transfer of heat through the chamber and away from the one or more heat-dissipating components.
Patent WO-2021183589-A1 (WO)
Title: Accessory attachment apparatus and methods related thereto
Inventor: DIMEGLIO DAWN
IPC: H05K5/03
Filed: 2021-03-10
Abstract: Disclosed herein are accessory attachment apparatuses, comprising: a spring bar having a first end and a second end, the first end having a first depressible tip and the second end having a second depressible tip, each being configured to communicate with a first and second recess, respectively; a spring bar housing having an interior channel and configured to contain the spring bar; and a coupler disposed on an outer surface of the spring bar housing, the coupler having an outer size and an inner size, the inner size defining an interior space, the coupler comprising: an abutting segment in communication with the spring bar housing; a distal segment positioned opposite the abutting segment; and a first and a second spanning segment configured to span the abutting segment and the distal segment and to communicate thereto.
Patent WO-2021206949-A1 (WO)
Title: Intradialytic monitoring of hemodynamic status based on detection of oxygen signature phase shift
Inventor: KOTANKO PETER
IPC: A61M1/36
Filed: 2021-03-29
Abstract: A hemodialysis system includes: a hemodialysis machine configured to provide hemodialysis treatment to a patient, wherein the hemodialysis treatment includes circulating extracorporeal blood of the patient through an extracorporeal blood circuit; a first oxygen saturation sensor device configured to measure oxygen saturation corresponding to the extracorporeal blood of the patient in the extracorporeal blood circuit; a second oxygen saturation sensor device configured to measure oxygen saturation corresponding to blood flowing within the patient; and at least one controller configured to determine one or more oxygen saturation phase shift (OSPS) values or one or more transcutaneous travel time values corresponding to the patient based on oxygen saturation measurements from the first oxygen saturation sensor device and the second oxygen saturation sensor device.
Patent WO-2021207325-A1 (WO)
Title: Natural extract and their components for use in mitigating acute respiratory distress syndrome
Inventor: CHAUDHURI RATAN
IPC: A61P11/00
Filed: 2021-04-07
Abstract: A method of treating or inhibiting the symptoms of acute respiratory distress syndrome, especially that associated with Covid-19, said method comprising administering an effective amount of a cytokine and/or innate immune response modulating natural extract, its components or metabolites, or combinations thereof capable of modulating those cytokine and/or innate immune response associated mechanisms associated with acute respiratory distress.
Patent WO-2021247144-A1 (WO)
Inventor: RHODES DAVID
IPC: D21F11/00
Filed: 2021-04-12
Abstract: A press felt that includes a base fabric with a machine side and a paper support side, and at least one PS batt layer made of batt fibers. A non-woven fusible web formed with fusible fibers or strands made of a same material type as the at least one PS batt layer is applied at least one of between the base fabric and the PS batt layer or between the PS batt layers. The fusible fibers or strands of the non-woven fusible web are punched through the base fabric along with the batt fibers during needling of the press felt to provide a uniform distribution through the base fabric and with the batt. During subsequent heat-setting, the non-woven fusible fibers or strands are melted and the material of the fusible fibers or strands is uniformly distributed through the batt and the base fabric to enhance batt retention.
Patent WO-2021231035-A1 (WO)
Title: Surface charge and power feedback and control using a switch mode bias system
Inventor: CARTER DANIEL
IPC: H01J37/00
Filed: 2021-04-19
Abstract: Systems, methods and apparatus for regulating ion energies in a plasma chamber and avoiding excessive and damaging charge buildup on the substrate surface and within capacitive structures being built on the surface. An exemplary method includes placing a substrate in a plasma chamber, forming a plasma in the plasma chamber, controllably switching power to the substrate so as to apply a periodic voltage function (or a modified periodic voltage function) to the substrate, and modulating, over multiple cycles of the periodic voltage function, the periodic voltage function responsive to a defined distribution of energies of ions at the surface of the substrate so as to effectuate the defined distribution of ion energies on a time-averaged basis, and to maintain surface charge buildup below a threshold.
Patent WO-2021222035-A1 (WO)
Inventor: ZHU JUN
IPC: H04B7/08
Filed: 2021-04-23
Abstract: This disclosure provides systems, devices, apparatus and methods, including computer programs encoded on storage media, for applying a zero element beam to conserve power in search and measurement operations of a UE. The UE may determine to measure a set of SSBs, where each SSB of the set of SSBs is transmitted on four symbols, and further determine a subset of the SSBs for which less than the four symbols associated with the SSBs are to be used for measurement of the SSBs. The UE may measure each SSB of the subset of the SSBs through less than the four symbols associated with the SSB.