baber/WOPTO huggingface dataset:
Patent DE-69810986-T2 (DE)
Inventor: DING NI
IPC: A61F2/82
Filed: 1998-04-21
Granted: 2003-10-30
Abstract: The invention is directed to medical devices having a drug-releasing coating and methods for making such coated devices. The coating permits timed or prolonged pharmacological activity on the surface of medical devices through a reservoir concept. Specifically, the coating comprises at least two layers: an outer layer containing at least one drug-ionic surfactant complex overlying a reservoir layer containing a polymer and the drug which is substantially free of an ionic surfactant. Upon exposure to body tissue of a medical device covered with such coating, the ionically bound drug in the outer layer is released into body fluid or tissue. Following release of such bound drug, the ionic surfactant binding sites in the outer layer are left vacant. To maintain the pharmacological activity after delivery of the ionically bound drug, additional amounts of the drug are embedded or incorporated in the reservoir layer in a manner which allows the drug, which is substantially free of ionic surfactants, to complex with the vacant binding sites of the ionic surfactant of the outer layer. As a result, the surface of the medical device is enriched with the drug to provide sustained pharmacological activity to prevent the adverse reaction due to the presence of the medical device. The invention is further directed to medical devices with stabilized drug-releasing coatings. The coatings are stabilized by exposure to a low energy, relatively non-penetrating energy source, e.g., gas plasma or an electron beam energy source.
Patent DE-69816056-T2 (DE)
Inventor: STURM HUBERT
IPC: A61P31/04
Filed: 1998-04-02
Granted: 2004-04-15
Abstract: Cefdinir in the form of a salt with dicyclohexylamine, a process for its production and its use in the purification of impure cefdinir.
Patent DE-69817368-T2 (DE)
Inventor: BRABRAND KNUT
IPC: A61B19/00
Filed: 1998-06-29
Granted: 2004-06-09
Abstract: A method and an apparatus for assisting percutaneous computed tomography-guided surgical activity inside a human or animal body, such as withdrawal of body tissue or body liquid sample, withdrawal of excess body liquid, insertion or injection, said method for determining insertion depth, transversal insertion angle and craniocaudal insertion angle for a needle-type surgical instrument to be inserted into the human or animal body from an insertion entry point on a skin surface of said body to a target inside said body. From a first tomography image coordinate values of said entry point are determined, and from said first or a second tomography image coordinate values of said target point are determined. Based on said coordinate values values of said insertion depth, transversal insertion angle and craniocaudal insertion angle are calculated. Said calculated values are applied to an instrument insertion guiding apparatus positioned adjacent said body in no physical contact therewith, said apparatus having a laser which provides a laser beam, manipulating adjustment means on said apparatus to let the laser beam assume the values of transversal insertion angle and craniocaudal insertion angle and to let the laser beam point at the entry point. The instrument with a needle pointed end thereof is located at said entry point and a longitudinal axis of the instrument is aligned with said laser beam, the aligning being made by letting a distal end face of said instrument be pointed at by said laser beam.
Patent DE-69818445-T2 (DE)
Inventor: HUBER T
IPC: A61K38/55
Filed: 1998-04-30
Granted: 2004-07-22
Abstract: A method for stimulating proliferation of T-cells containing cytoplasmic post-prolyl dipeptidase activity; the method, in one aspect, involves contacting the T-cells with an organic compound at a concentration below 10<SUP>-8</SUP>M, wherein the compound is characterized in that: (a) it is capable of crossing the membrane of T-cells to enter the cytoplasm, (b) it binds to the dipeptidase activity at a concentration of below 10<SUP>-8</SUP>M, and thus (c) stimulates proliferation of the T-cells at that concentration.
Patent DE-69818650-T2 (DE)
Inventor: TERSTAPPEN W
IPC: G01N33/553
Filed: 1998-03-24
Granted: 2004-08-12
Abstract: Apparatus and methods are disclosed which facilitate immobilization of magnetically labelled particulate entities, e.g., cells, preferably in a defined pattern, on a collection surface via binding between specific binding pair members, as an aid to particle analysis.
Patent DE-69824552-T2 (DE)
Inventor: WALKER E
IPC: B27K3/50
Filed: 1998-01-16
Granted: 2005-08-25
Abstract: The present invention provides a waterproofing wood preservative system comprising a waterproofer selected from the group consisting of an alkyl amine oxide, an alkyl acetoacetate, and a waterproofing quaternary ammonium compound and a biocide comprising at least one biocidal quaternary ammonium compound wherein said waterproofing quaternary ammonium compound is a C12-C30 alkyl or C6-C20 aryl-substituted alkyl, C12-C30 alkyl quaternary ammonium composition and said biocidal quaternary ammonium compound is a C8-C12 alkyl or C6-C20 aryl-substituted alkyl, C8-C10 alkyl quaternary ammonium composition. Said wood preservative system offers protection against both biological and physical decomposition of wood, as for example, that occurring in long term-weathering.
Patent DE-69824848-T2 (DE)
Inventor: BRAGAGLIA MICHELA
IPC: A61M25/02
Filed: 1998-04-30
Granted: 2005-07-21
Abstract: An intravenous infusion device (1) having a needle (3) connectable to a flexible infusion tube (4), an element (2) for fastening the needle (3) to the patient's body, and a cap (6) for protecting and covering the needle (3); the device being characterized in that the element (2) for fastening the needle (3) to the patient's body is defined by a single wing (2), and in that the cap (6) has a longitudinal slot (7) in which the single wing (2) slides; the needle (3) being movable by the operator from a withdrawn position fully covering and protecting the needle, to a forward position exposing the needle for use, so as to provide, by means of the same cap (6), for protecting the needle (3) prior to use, and for protecting the needle (3) after use.
Patent DE-69900544-T2 (DE)
Inventor: CARLI FABIO
IPC: A61K47/44
Filed: 1999-02-05
Granted: 2002-08-22
Abstract: Process for the preparation of pharmaceutical compositions comprising one or more polymers and one or more drugs by the extrusion and spheronization technique, wherein polymers belong to the group of the cross-linked amphiphilic polymers.
Patent DE-69903080-T2 (DE)
Inventor: VIGNALI GRAZIANO
IPC: C04B33/14
Filed: 1999-03-02
Granted: 2003-05-28
Abstract: Composition whereby ceramic manufactured articles, obtained by moulding a conventional ceramic mixture without added TiO2., are coloured from yellow to orange, said composition consisting of an aqueous solution of inorganic compounds or organic complexes of titanium and chromium combined with antimony or tungsten or mixtures thereof, in quantities corresponding to 2 to 6% by wt. Ti, 3 to 12% Sb (or 4 to 14% tungsten) and 0.2 to 2.5% chromium.
Patent DE-69909166-T2 (DE)
Inventor: BORODANI PANDELI
IPC: B60W40/08
Filed: 1999-04-14
Granted: 2004-01-15
Abstract: The system (1) includes a memory (8) in which curves (A, B) are stored which define the conditions for each gear change, corresponding to at least two reference styles of driving, sensors (S1-S6) for operating parameters of the motor vehicle, and second processing devices (5, 6, 7) set up to estimate the value of a first index (IM) which identifies the kind of driving of the motor vehicle and, respectively, the value of a second index (IS) which defines the manner or style of driving of the driver, and a processing and control unit (ECU). This unit (ECU) is set up to perform a learning procedure in which it acquires and memorises the value of the second index (IS) corresponding to the manner or style of driving of the driver during a test drive with manual control of the gears, and generates and memorises maps of modified curves (C) defining the conditions for the gear changes according to a personalised style of driving from among the said reference methods, and an automatic control procedure in which it controls actuators (3, 4) in order automatically to effect the gear changes based on the modified curves (C) generated during the learning procedure. <IMAGE>
Patent DE-69912744-T2 (DE)
Inventor: BRADBURY ARTHUR
IPC: B65G69/18
Filed: 1999-01-22
Granted: 2004-08-19
Abstract: A system for providing passive dust control for a transfer of bulk material from a first station to a second station in a material handling system. A dust containment housing encloses a first station and a second station. Bulk material is transferred from the first station to the second station inside the dust containment housing. A region of low pressure inside the dust containment housing is defined by a circulation compartment. Air carrying suspended particles of bulk material flows from a region of high air pressure generated by the transfer of bulk material to the region of low air pressure. The suspended particles of bulk material either remain suspended in the air inside the housing or settle out of the air into the bulk material inside the housing.
Patent DE-69918694-T2 (DE)
Inventor: SONG XIAOQING
IPC: C09K23/42
Filed: 1999-08-03
Granted: 2005-07-21
Abstract: A stable aqueous rinse aid dispersion includes a low foaming nonionic surfactant present in a range of from about 2% to about 80% by weight of the rinse aid dispersion, a hydrotrope present in a range of from about 0.5% to about 20% by weight of the rinse aid dispersion, and a partially neutralized poly(meth)acrylic acid polymer present in a range of from about 0.1% to about 15% by weight of the rinse aid dispersion, wherein the polymer is at least 75% non-neutralized. The poly(meth)acrylic acid polymer has an average molecular weight in a range of from about 1000 to about 50,000. The rinse aid dispersion has a pH in a range of from about 2 to about 6. The stable aqueous rinse aid dispersion is essentially free of a high molecular weight compatibilizing polymer.
Patent DE-69928995-T2 (DE)
Inventor: MCGALL GLENN H
IPC: C07F9/655
Filed: 1999-06-21
Granted: 2006-09-07
Abstract: New compounds, compositions and methods which find application in solid phase synthesis including the preparation of high-density arrays of diverse polymer sequences such as diverse peptides and oligonucleotides as well as in preparation of arrays of small ligand molecules. The compounds of the present invention are those which are typically referred to as linking groups, linkers or spacers and include unsymmetrical disulfide linking groups, and 1,3-diol derivatives capable of providing a triggered release of an attached compound from a solid support under mild conditions. Additional new compounds are labels which can be incorporated into either the 3' or 5' terminus of a DNA oligomer.
Patent DE-69935677-T2 (DE)
Inventor: TROGOLO JEFFREY A
IPC: A61L29/16
Filed: 1999-11-16
Granted: 2007-07-12
Abstract: The invention relates to an antibiotic coated substrate having an antibiotic coating composition coated thereon. The coating composition is formed of a hydrophilic polymer having antibiotic ceramic particles, preferably antibiotic zeolite, dispersed therein. The antibiotic zeolite may further comprise a discoloration agent. Another embodiment of the invention is an article comprising a substrate on which is coated the antibiotic hydrophilic coating composition. A method for preparing the antibiotic hydrophilic polymer coating on a substrate is also provided.
Patent HU-E028158-T2 (HU)
Title: Synthesis of azo bonded immunoregulatory compounds
Inventor: SAUTHIER JENNIFER A RIGGS
Filed: 2005-07-07
Abstract: Methods are disclosed for preparing compounds of Formula I: where R1, R3, and R4 are independently hydrogen or C1 to C4 alkyl, and R2 is: where R5 is selected from the group consisting of hydrogen and C1 to C4 alkyl, or where R6, R7 and R8 are independently hydrogen or C1 to C4 alkyl; or the esters or pharmacologically acceptable salts thereof. The compounds and or their metabolites can be used to treat or prevent various diseases, particularly inflammatory conditions of the GI tract.
Patent HU-E025491-T2 (HU)
Title: Sustained release of antiinfectives
Inventor: BONI LAWRENCE T
IPC: A61K31/407
Filed: 2003-10-29
Abstract: The present invention relates to formulations useful for the sustained release of antiinfectives. In particular, it relates to a liposomal anti-infective for use in treating or ameliorating a pulmonary infection in a patient, wherein the anti-infective is an aminoglycoside.
Patent HU-E034873-T2 (HU)
Title: Process for preparing genetically transformed yeasts capable of producing a molecule of interest at a high titre
Inventor: BROCARD-MASSON CORINNE
IPC: C12N15/81
Filed: 2012-06-18
Abstract: The subject of the present invention is a process for preparing a genetically modified yeast by multicopy integration of at least four expression cassettes, allowing the production of a molecule of interest at high titre. The subject of the present invention is also yeasts transformed according to said process, and the use thereof for producing hydrocortisone.
Patent HU-E034596-T2 (HU)
Title: Ti-al-based heat-resistant member
Inventor: KOYANAGI YOSHIHIKO
IPC: C21D1/19
Filed: 2015-03-20
Abstract: The present invention relates to a Ti-Al-based heat-resistant member including a Ti-Al-based alloy which includes: 28.0 mass% to 35.0 mass% of Al; 1.0 mass% to 15.0 mass% of at least one selected from the group consisting ofNb, Mo, W and Ta; 0.1 mass% to 5.0 mass% of at least one selected from the group consisting of Cr, Mn and V; and 0.1 mass% to 1.0 mass% of Si, with the balance being Ti and unavoidable impurities, in which a whole or a part of a surface of the Ti-Al-based heat-resistant member includes a hardened layer as a surface layer, the hardened layer having a higher hardness than an inside of the Ti-Al-based heat-resistant member, and the Ti-Al-based heat-resistant member has a hardness ratio (a hardness of the surface layer / a hardness of the inside) of 1.4 to 2.5.
Patent TR-200001655-T2 (TR)
Title: Ekinokandin türevleri, hazırlama yöntemi ve anti-fungal maddeler
Inventor: COURTIN OLIVIER
IPC: A61K38/00
Filed: 1998-12-09
Abstract: Bulus, formül (I) bilesimleri ile ilgilidir ki burada: ya da R1 ve R2=H, OH, istege bagli olarak ikame edilmis alkildir ya da NR1, NR1R2 'yi tasiyan karbon ile birlikte bir çift bag olusturur ve R2 Xra'dir ki burada X O, NH ya da N-alkildir ve Ra H, istege bagli olarak ikame edilmis alkildir; R=10 adete kadar karbon atomu ihtiva eden, istege bagli olarak bir ya da pek çok heteroatom, bir ya da pek çok heterosiklden meydana gelen bir zincir; T=H2, CH2, CH2CONH2, CH2C=N, (CH2)2NH2; Y=H, halojen ; W=H; OH; Z=H ya da CH3. Söz konusu ürünler anti-fungal özelliklere sahiptirler.
Patent TR-200101111-T2 (TR)
Title: Dönüştürülmüş alkil benzen sülfonat ihtiva eden çamaşır deterjanları.
Inventor: KOTT KEVIN LEE
IPC: C11D17/06
Filed: 1999-10-13
Abstract: Dönüstürülmüs alkilbenzen sülfonat yüzey aktif ajan karisimlari spesifik dalli ve dalli olmayan alkilbenzen sülfonat terkiplerin bir karisimini ihtiva eder ve ayrica özelligi 275-10.000 arasinda 2/3-fenil indeksidir. Bu karisimlari içeren deterjan ve temizlik ürünleri de ifsa edilmistir.
Patent TR-200102533-T2 (TR)
Title: Proteaz inhibitörleri
Inventor: ALLEN DARIN ARTHUR
IPC: A61K31/428
Filed: 1999-12-17
Abstract: Bu-buluş,A-B,(I) Formülünün yeni bileşiklerini, bu bileşiklerin ön-ilaç biçimlerini ya da farmasötik açıdan kabul edilebilir tuzlarını temin etmektedir,bu formülde,A, bir doymuş doymamış ya da bir kısmen doymamış bisliklik heterosiklik halka yapısını temsil etmektedir ve B, bir aril ya da bir heteroaril grubunu temsil etmektedir. Bu buluşun tercihedilen bir benzimidazol ya da indol çekirdeğini içermektedir. Bu buluşun bileşikleri serin proteazları,Ürokinaz(uPA), Faktör Xa (FXa) ve/veya Faktör Vlla'nın (FVlla) inhibitörleridir ve memelilerde tromboembolik bozuklukların engellenmesi ya da iyileştirilmesi için pıhtılaşmaya karşı maddeler ve/veya kansere karşı maddeler olarak kullanıma sahiptir.
Patent TR-200102601-T2 (TR)
Title: Prematüre memelilerde spesifik mide-bağırsak olgunlaşmasına yönelik besleme bileşimi
Inventor: GARCIA-RODENAS CLARA L
IPC: A23L33/15
Filed: 2000-03-01
Abstract: Genç memelilerin olgunlasmamis mide-bagirsak sistemlerinin gelismesini ve olgunlasmasini desteklemeye yönelik, bir protein kaynagi olarak diyet proteini hidrolizatlari ile kismen biyoaktif peptitler biçiminde saglam proteinlerin bir karisimini içeren enteral bir besleme bilesimi.
Patent TR-200103607-T2 (TR)
Title: Pürin Türevleri
Inventor: MANTELL SIMON JOHN
IPC: A61P31/04
Filed: 2000-06-13
Abstract: Bu bulus formül (I)'i havi bilesikler ve bunlarin farmasötik yönden kabul edilebilir tuzlari ve solvatlari ve bu gibi bilesiklerin hazirlanmasina yönelik prosesler,bu gibi bilesiklerin hazirlanmasinda kullanilan ara maddeler ve bu gibi bilesikleri ihtiva eden kompozisyonlar ve bu gibi bilesiklerin adenosin A2a reseptörü agonistleri olarak kullanimi ile ilgilidir.
Patent TR-200201959-T2 (TR)
Title: Sürekli poli(trimetilen tereftalat) üretme işlemi.
Inventor: GIARDINO CARL J
IPC: C08G63/78
Filed: 2000-08-10
Abstract: Sürekli bir poli(trimetilen tereftalat) üretme islemi ortaya konulmaktadir. isleme göre bis-3-hidroksipropil tereftalat ve/veya molekül agirliklari düsük 1,3-propandiol ve tereftalik asit polyesterleri ihtiva eden sivi bir besleme karisimi (sivi besleme karisiminda propilen gruplarinin tereftalat gruplarina mol orani 1.1 ila 2.2'dir), bir flasöre beslenir. Gaz halindeki yan ürünlerin birinci akisi sürekli olarak buharlastirilir ve flasörden çikarilir ve propilen gruplarinin tereftalat gruplarina mol orani 1.5'ten az olan bir sivi flasör reaksiyon ürünü, sürekli olarak flasörden çekilir.
Patent TR-200500106-T2 (TR)
Title: Kenarından çekilerek açılabilen kapak yapısı.
Inventor: WILSON ALASTAIR IAN
IPC: B65D17/50
Filed: 2003-06-30
Abstract: Özellikle gida ihtiva eden teneke kutularin kapatilmasinda kullanilmak üzere bir kenarindan çekilerek açilabilen kapak yapisi, teneke kutunun muhtevasinin islenmesi için ve/veya kutunun tutulma islemleri için merkez panel üzerine katlanan ve katlanmis konumda sabitlenen bir kisa uzantiya sahiptir. Kisa uzanti yerine sabitlenirken, alüminyum barindirmayan ya da az miktarda alüminyum barindiran, pahali olmayan bir katmanli yapisi kullanilabilmektedir. Kenarindan çekilerek açilabilen kapak yapisinin olusturulma yöntemleri, bir isiyla yapistirilabilir malzeme tabakasi ve/veya bir yapistirici tabakasinin, kisa uzantinin, bu tabakanin üzerine katlanabildigi ve örnegin, isiyla yapistirma ile bu tabakaya yapistirilabildigi sekilde açikta birakilmasini kapsamaktadir.
Patent DE-602004010679-T2 (DE)
Inventor: THOMAS EDWARD N
IPC: A43B13/20
Filed: 2004-08-18
Granted: 2008-11-27
Abstract: The invention relates to a fluid-filled bladder and a method for making for making a fluid-filled bladder that include a core having at least one fusing filament. A portion of the fusing filament is positioned adjacent to the exterior surface of the core such that it engages and fuses to barrier layers of the bladder, thereby securing the core to the barrier layers without the need for an additional fusing agent therebetween.
Patent DE-602004011140-T2 (DE)
Inventor: DALLET HERVE
IPC: G06F3/02
Filed: 2004-04-19
Granted: 2009-01-02
Abstract: The operating terminal (10) includes two function keys (16) that can be pressed by an operator to performing either of the two Boolean control actions specific to a display line, after the corresponding line has been selected. The function keys can be unambiguously designated by the Boolean control action symbols. The line displayed on the display (13) defines two Boolean control actions applicable to at least one automation device. The line contains two corresponding symbols representing Boolean control actions.
Patent DE-602004011504-T2 (DE)
Inventor: LORENZ CRISTIAN
IPC: A61B6/00
Filed: 2004-04-14
Granted: 2009-02-19
Abstract: The semi-automatic extraction and delineation of the cardiac region of interest in computer tomographic angiography images is time consuming and requires an experienced operator. According to the present invention, a completely automatic delineation and extraction of the CROI is provided, wherein the chest wall is detected and the region where the CROI is attached to the chest wall. Then, the descending aorta is detected. After that a circular initialization of a closed contour around a part of the CROI is performed, which is optimized in a subsequent step. Then, a propagation is performed through all slices of the CTA image, where the preceding contour of the preceding slice image is used for an actual contour optimization in the actual slice image. Advantageously, a fully automatic delineation and extraction of the CROI is provided within very short time.
Patent DE-602004011526-T2 (DE)
Inventor: ANDREAS THOMAS
IPC: F17C13/04
Filed: 2004-11-04
Granted: 2008-08-21
Abstract: A gas tank containing a compressed combustible gas is equipped with a safety relief system (18) providing an emergency discharge of the compressed combustible gas through a relief line 21. The safety relief system (18) comprises a pressurized triggering hose (24) that extends through a selected risk area around the tank, wherein a rupture of the triggering hose, due to a temperature increase or mechanical damage, results in a pressure drop in the safety relief system (18) that triggers an emergency discharge of said pressurized combustible gas from said gas tank (10).
Patent DE-602004012307-T2 (DE)
Inventor: NERAAL RUNE
IPC: A23L17/00
Filed: 2004-10-08
Granted: 2009-03-19
Abstract: A method for the preparation of frozen fish mass of white fish is described, suitable for use as strating material for the fish product industry, wherein the fish material provides improved binding and consistency forming properties through the addition of an organic acid or a salt thereof as well as a cryo-preservative.
Patent DE-602005005809-T2 (DE)
Inventor: GRAF JOHN FREDERICK
IPC: C08K5/00
Filed: 2005-04-22
Granted: 2009-04-30
Abstract: The color stability of a multilayer article comprising a top layer and and a substrate layer is enhanced by the addition of at least one unstable yellow colorant and optionally, at least one stable chromatic colorant to the top layer. The substrate layer includes a scattering white pigment and optionally, at least one stable chromatic colorant. Methods for making the aforementioned multilayer article are also provided in the present invention.
Patent DE-3588022-T3 (DE)
Inventor: NEURATH ALEXANDER ROBERT
IPC: A61K47/48
Filed: 1985-02-28
Granted: 2000-02-24
Abstract: A hepatitis B vaccine containing a peptide with an amino acid chain of at least six consecutive amino acids within the pre-S gene coded region of the envelope of hepatitis B virus. The vaccine being free of an amino acid sequence corresponding to the naturally occuring evelope proteins of hepatitis B virus and a physiologically acceptable diluent. The peptide being free or linked to a carrier. The carrier being a conventional carrier or a novel carrier including a lipid vesicle stabilized by cross-linking and having covalently bonded active sites on the outer surface thereon. Such novel carrier being useful not only to link the novel peptide containing an amino acid chain with amino acids within the pre-S gene coded region of the surface antigen of hepatitis B virus, but can also be used to bind synthetic peptide analogues of other viral proteins, as well as bacterial, allergen and parasitic proteins of man and animals. The peptides of the invention can be utilized in diagnostics for the detection of antigens and antibodies.