baber/WOPTO huggingface dataset:
Patent CA-3094015-A1 (CA)
Title: Use of alginate oligomers to enhance the translocation of micro/nanoparticles across mucus layers
Inventor: TAGALAKIS ARISTIDES
IPC: A61K47/61
Filed: 2019-03-19
Abstract: The invention provides methods for translocating micro/nanoparticles and molecules or interest carried thereby across mucus layers. More specifically there is provided a method for translocating a cationic micro/nanoparticle across a mucus layer said method comprising (a) contacting the mucus layer with at least one alginate oligomer, said alginate oligomer having at least 70% mannuronate residues, together with the cationic micro/nanoparticle; or (b)(i) contacting the cationic micro/nanoparticle with an alginate oligomer having at least 70% mannuronate residues thereby forming a micro/nanoparticle carrying said alginate oligomer, and (b)(ii) contacting the mucus layer with the micro/nanoparticle prepared in step (b)(i). There is also provided a method for translocating a molecule of interest across a mucus layer said method comprising contacting the mucus layer with a micro/nanoparticle which is formed of self-assembling micro/nanoparticle forming components, wherein at least one is a cationic micro/nanoparticle forming agent and at least one is an alginate oligomer which has at least 70% mannuronate residues, and further comprises said molecule of interest, optionally wherein the molecule of interest is covalently bound to one or more of the self-assembling micro/nanoparticle forming components. The invention further relates to the use of alginate oligomers in the methods of the invention and to micro/nanoparticles of the invention.
Patent CA-3094827-A1 (CA)
Title: Drug conjugates of cmet monoclonal binding agents, and uses thereof
Inventor: CORONELLA JULIA
IPC: A61P35/00
Filed: 2019-03-27
Abstract: Presented herein are novel monoclonal cMET binding agents that are conjugated to pyrrolobenzodiazepine toxins, composition thereof and uses thereof for the treatment of cancer.
Patent CA-3096970-A1 (CA)
Inventor: MANENTI GIOVANNI
IPC: F28D7/10
Filed: 2019-04-04
Abstract: A double-tube heat exchanger is described, comprising an outer tube and an inner tube concentrically arranged so as to form a first annular gap in between the outer tube and the inner tube. The outer tube is provided with at least an inlet connection and with at least an outlet connection for inletting and outletting, respectively, a first fluid flowing in the first annular gap. The inner tube is provided with at least a first inlet connection and with at least a second outlet connection for inletting and outletting, respectively, a second fluid flowing in the inner tube for an indirect heat exchange with the first fluid. The inlet and outlet connections of the inner tube are jointed to equipment or conduits placed upstream and/or downstream of the heat exchanger. The inner tube is formed by at least two tube sections, jointed each other by a joint of butt-to-butt type. One of the tube sections is integrally formed, as a single monolithic piece, with an assembly wall which joints a first end of the outer tube to the inner tube, so to seal the first annular gap at the first end of the outer tube. A second annular gap is formed in between the inner tube, or the equipment or conduits, or the inner tube and the equipment or conduits, and the assembly wall. The second annular gap is exposed to the air and is in fluid communication neither with the first annular gap nor with the inner tube, and is at least partially surrounded by the first annular gap.
Patent CA-3102605-A1 (CA)
Inventor: BELLISSIMO MARK JOSEPH
IPC: B27M3/00
Filed: 2019-06-07
Abstract: Disclosed herein are various systems, sub-system, and methods for the manufacture of a wall module for using in building a modular construction unit, e.g., for using in building residential homes, commercial offices, educational or service facilities, eir.using a substantially entirely automated modular construction technique. According to the disclosure herein, the resulting wall module includes an internal wall frame including wall studs attached between a top plate and a bottom plate, with one or more framing sub-assemblies attached therein to define openings through the wall module. The wall frame has suitable panel members the respective surfaces thereof corresponding to the interior and exterior surfaces of the modular construction unit. The wall frames, when completely assembled, can be transported to be assembled with other constituent components of the modular construction unit to complete the manufacture of the modular construction unit.
Patent CA-3104050-A1 (CA)
Title: Low impact running
Inventor: DE CLERCQ DIRK
IPC: G16H20/30
Filed: 2019-06-25
Abstract: A method (100) for gait retraining of a runner (10). The method comprises: measuring (110) acceleration data of at least one lower leg of the runner; diagnosing (120) the acceleration data thereby determining a measure of the impact intensity of at least one external tibial shock; and providing (130) real-time feedback to the runner by converting the measure of the impact intensity into distortion of music to a level which is perceived by the runner as a measure for the impact intensity. The conversion is done based on a predefined relationship between perceived distortion levels and imposed distortion levels, and the runner can reduce the distortion of the music by adjusting his or her gait.
Patent CA-3112604-A1 (CA)
Inventor: QIU JIA SEN
IPC: E05B17/00
Filed: 2021-03-18
Abstract: An anti-unlocked mechanism comprises a transmission gear, a sliding rod, a locking member and a first elastic member. The transmission gear includes an arc surface. An end of the sliding rod contacts the deadbolt of the lock body. The sliding rod is provided with a fixed stopper and a second elastic member. When the deadbolt is retracted, the sliding rod moves with the deadbolt against the elastic force of the second elastic member. When the deadbolt extends, the locking member moves with the sliding rod to block the rotation of the rotating part. The first elastic member comprises first and second protrusions. The second protrusion will not hinder the fixed stopper of the slide rod unless the first protrusion contacts with the circular arc surface, which will block the movement of the locking member to block rotation of the rotating part.
Patent CA-3114487-A1 (CA)
Inventor: PURDY CLAY
IPC: C02F5/08
Filed: 2021-04-09
Abstract: The present invention discloses a novel aqueous composition for use in removing petroleum-contaminated barium sulfate scale from a surface contaminated with such, said composition comprising:  a chelating agent and a counterion component selected from the group consisting of: Li5DTPA;  Na5DTPA; K5DTPA; Cs5DTPA; Na4EDTA; K4EDTA; TEAH4DTPA; and TBAH5DTPA; a scale removal enhancer; a non-ionic surfactant; and a hydrotrope. There is also disclosed methods to use such compositions.
Patent CA-3115444-A1 (CA)
Inventor: CONN EDWIN DIXON III
IPC: E21B7/02
Filed: 2019-10-08
Abstract: A drilling rig mobility system moves a drilling rig or similar structure in an oilfield or similar environment and includes independently controllable positioning shoes attaching to the drilling rig and controlable through separate and coordinated position control commands. Each positioning shoe may be individually addressed to reposition the drilling rig. Each positioning shoe includes a hydraulic actuator and wireless control circuitry. The hydraulic actuator provides vertical, horizontal and rotational force in response to wireless control signals for wireless position and control data and instructions with a remote wireless communications device. A cylinder stomper vertically elevates the hydraulic actuator and receives and transfers the vertical and rotational force. A foot assembly transfers the horizontal force from the hydraulic actuator. A positioning shoe cylinder stomper and positioning shoe traverse cylinder provide infinitely variable position control.
Patent CA-3119354-A1 (CA)
Title: Valve seat with seal for use with valve element in valve assembly
Inventor: MASEN MARK GEOFFREY
IPC: F16K5/20
Filed: 2021-05-21
Abstract: A valve assembly includes a valve body defining a fluid inlet in fluid communication with a fluid outlet. The valve body has an inner body surface defining an interior chamber extending between the fluid inlet and the fluid outlet. A valve element is disposed within the interior chamber and rotatable through a range of positions relative to the outlet providing a high level of precision control of a fluid flow rate through the valve assembly. A valve seat with a seal is positioned around a valve element. The valve seat is configured to self-adjust its inner radial diameter to correspond to the outer radial diameter of the valve element to maintain a portion of an inner seat surface in contact with an outer valve surface of the valve element through the range of positions.
Patent CA-3119713-A1 (CA)
Title: Anticancer composition
Inventor: SUH MAN-CHUL
IPC: A61K31/155
Filed: 2019-11-11
Abstract: The present invention relates to a composition comprising, as active ingredients: (1) a biguanide-based compound or a pharmaceutically acceptable salt thereof; (2) 2-deoxy-D-glucose; and (3) inositol hexaphosphate or a pharmaceutically acceptable salt thereof, inositol, or a mixture thereof. The composition according to the present invention exhibits a synergistic anticancer effect by appropriately combining specific drugs having a problem that needs to be used in a large amount, thereby making it possible to kill cancer cells in a small amount and effectively treat the cancer. Furthermore, the composition of the present invention may kill only cancer cells without side effects by exhibiting a specific toxic effect on cancer cells without showing toxicity on normal cells and thus may be usefully used as an anticancer agent and for preventing or improving cancer.
Patent CA-3120977-A1 (CA)
Inventor: LEV-TOV AMIR
IPC: G06F7/00
Filed: 2018-11-19
Abstract: La présente invention concerne des procédés, des systèmes et un produit programme d'ordinateur pour effectuer automatiquement une analyse de sentiment sur des textes, tels que des transcriptions d'appel téléphonique et des communications écrites électroniques. Les techniques décrites comprennent, entre autres, l'apprentissage de lexique, la gestion de négations et d'éléments de décalage, l'élagage de lexiques, le calcul de confiance pour l'orientation de jeton, la personnalisation supervisée, le mélange de lexiques et la segmentation adaptative.
Patent CA-3125860-A1 (CA)
Inventor: DUMAIS ANDRE
IPC: C25C7/08
Filed: 2021-07-23
Abstract: Automated robotic harvesting systems and methods for harvesting electrodeposited metals from a cell, and specialized end of arm tooling for use in automated robotic harvesting systems and methods for harvesting electrodeposited metals from a cell, are disclosed. A harvesting tool comprises an extraction gripping unit configured to extract a starter sheet and metal electrodeposited on the starter sheet from a cell, and a harvesting gripping unit configured to separate the starter sheet from the metal for harvesting the metal.
Patent CA-3126834-A1 (CA)
Inventor: WAXMAN ALLEN M
IPC: G01M3/38
Filed: 2020-01-24
Abstract: La présente invention concerne des systèmes et des procédés destinés à une approche d'imagerie basée sur une absorption multispectrale qui offre une détection, une localisation et une quantification améliorées d'émission de gaz. La technologie d'imagerie révélée par l'invention fait appel à un capteur optique et à un éclairage à large bande en combinaison avec des installations de réflecteurs spécialisés montées autour du site. Le capteur optique détecte de la lumière (par exemple, réfléchie) provenant de positions le long de l'installation de réflecteur. Des lignes de visée du capteur optique à des positions le long de l'installation de réflecteur balayent un "rideau optique" entourant partiellement et/ou formant une limite proche de divers actifs à surveiller. Des signatures d'absorption optique provenant d'un gaz de fuite traversant le rideau optique peuvent servir à détecter, localiser et obtenir des mesures quantitatives caractérisant la fuite. Des mesures provenant d'installations de réflecteurs peuvent être combinées à des mesures obtenues par le biais d'une réflexion de lumière ambiante provenant de matériaux de fond selon une approche hybride qui étend les capacités de surveillance et qui offre des améliorations de détection.
Patent CA-3130795-A1 (CA)
Title: Spectrometer system and method for testing of same
Inventor: KERSTAN FELIX
IPC: G01J3/02
Filed: 2019-12-18
Abstract: The present invention relates to a spectrometer system and a method for testing of same. The spectrometer system comprises a housing provided with a window, an illumination source, a spectrometer and a standard for internal recalibration being disposed in said housing. Specific absorption bands of a filling gas present in the housing are identified in a reference spectrum, which was recorded using the standard, wherein a wavelength characterizing the relevant identified specific absorption band is measured in each case such that measured values are obtained for the wavelengths of the absorption bands. A test spectrum is recorded by the spectrometer using the standard. The specific absorption bands of the filling gas are identified in the test spectrum, wherein a wavelength characterizing the relevant identified specific absorption band is measured in each case such that measured values are obtained for the wavelengths of the specific absorption bands. According to the invention, a test is carried out to establish whether the measured values of the wavelengths of the absorption bands identified in the test spectrum deviate by no more than a predetermined measure from the measured values of the wavelengths of the absorption bands identified in the reference spectrum.
Patent CA-3130928-A1 (CA)
Inventor: LEVNER DANIEL
IPC: B01L3/00
Filed: 2017-07-12
Abstract: Methods of removing bubbles from a microfluidic device are described where the flow is not stopped. Methods are described that combine pressure and flow to remove bubbles from a microfluidic device. Bubbles can be removed even where the device is made of a polymer that is largely gas impermeable.
Patent CA-3131005-A1 (CA)
Inventor: KAO CHIH-HUNG
IPC: F16K31/44
Filed: 2020-01-09
Abstract: A multi-directional touch valve, comprising a valve body and a pressing member connected to the valve body. The valve body comprises a housing, a primary flow channel and a switching mechanism. The housing comprises at least one support portion formed at the housing's water outlet end and protruding outwardly. The switching mechanism is inside the housing and selectively blocks the primary flow channel. The pressing comprises a water passage portion, at least one suspension portion movably connected to the at least one support portion and a push-abutment portion driving the switching mechanism to block the primary flow channel. As a motion space is formed on an inner side of the suspension portion and on the side thereof facing the housing's pipe connecting end, the switching mechanism is operable by pushing the pressing member from multiple directions.
Patent CA-3132575-A1 (CA)
Title: Compositions et methodes de traitement, d'amelioration et de prevention d'infections par h. pylori
Inventor: BORODY THOMAS JULIUS
IPC: A61K31/43
Filed: 2020-04-17
Abstract: L'invention concerne des combinaisons pharmaceutiques, des compositions et des kits comprenant au moins un inhibiteur de la H+/K+ ATPase et un composé antibiotique et des méthodes d'utilisation de ceux-ci dans le traitement, la prévention et l'amélioration d'infections par Helicobacter pylori chez un individu. Dans d'autres modes de réalisation, l'inhibiteur de la H+/K+ ATPase est un bloqueur d'acide compétitif du potassium (PCAB) et le composé antibiotique est choisi parmi les groupes comprenant les pénicillines, les rifamycines, les macrolides, les PCAB, les nitroimidazoles, les fluoroquinolones, les TG44, les nitrofuranes, les thiazolides, les acides salicyliques et les dérivés tels que les bismuths et les tétracyclines.
Patent CA-3134282-A1 (CA)
Inventor: KADOUS TAMER ADEL
IPC: H04B7/0456
Filed: 2020-04-22
Abstract: Des aspects de l'invention concernent un schéma de gestion d'ensemble actif mis en ?uvre par un ordonnanceur dans un réseau à entrées multiples et sorties multiples (MIMO) qui minimise les problèmes de capacité et d'interférence. Par exemple, l'ordonnanceur peut regrouper initialement chaque station de base en un ensemble actif séparé. L'ordonnanceur peut ensuite analyser chaque ensemble actif afin de déterminer si l'ensemble actif est bon ou mauvais en fonction du niveau d'interférence et du nombre de dimensions MIMO disponibles dans l'ensemble actif respectif. Si l'ordonnanceur détermine qu'un ensemble actif est mauvais, l'ordonnanceur peut déterminer un ensemble de métriques qui représentent chacune une capacité et une qualité de liaison qui résulteraient si l'ensemble actif mauvais était combiné à un autre ensemble actif. En fonction de l'ensemble de métriques, l'ordonnanceur peut combiner le mauvais ensemble actif avec un autre ensemble actif, et répéter ce processus jusqu'à ce qu'il ne reste plus aucun mauvais ensemble actif.
Patent CA-3137397-A1 (CA)
Title: Chimeric receptor that recognizes engineered site in antibody
Inventor: SAKURAI MIKA
IPC: C12N1/15
Filed: 2020-04-17
Abstract: The present disclosure provides a pharmaceutical composition to be used in combination with the administration of a mutant antibody that has a mutation involving the substitution, deletion, addition or modification of at least one amino acid in the CH1 region, CH2 region, CH3 region, CL region or framework region thereof, wherein: the pharmaceutical composition comprises cells expressing a chimeric receptor; the mutant antibody is capable of binding to the extracellular binding domain of the chimeric receptor via a part containing the mutation in the extracellular binding domain; and the extracellular binding domain does not bind to an antibody not containing the mutation.
Patent CA-3138228-A1 (CA)
Inventor: Liu Hui Shu
IPC: A47L11/292
Filed: 2021-11-08
Abstract: The present invention relates to a cleaning appliance and a method for a cleaning appliance. In particular, a cleaning appliance is disclosed, comprising: a housing, comprising an opening facing toward a surface to be swept; a sweeping brush, having a connection part by means of which the sweeping brush is mounted in the housing, and being capable of rotating about a rotation axis by receiving a driving force, so as to perform a sweeping operation; and a toothed structure arranged close to an end of the sweeping brush, the toothed structure being provided between the housing and the sweeping brush and comprising multiple teeth, the multiple teeth extending from one of the housing and the sweeping brush toward the other of the housing and the sweeping brush. The cleaning appliance of the present invention is at least able to prevent or at least reduce the entry of foreign matter into a gap, as well as promptly trigger protection measures when necessary to remind a user to deal with the problem, in order to avoid failure due to melting of the housing and sweeping brush in a connection region.
Patent CA-3138555-A1 (CA)
Title: Methods and apparatus for uplink (ul) multiplexing and prioritization in new radio (nr) communication
Inventor: TAHERZADEH BOROUJENI MAHMOUD
IPC: H04W72/12
Filed: 2020-04-30
Abstract: A wireless transmit/receive unit (WTRU) may receive a first higher layer configuration for a cancellation indication (CI). Further, the first higher layer configuration may include a set of reference frequency resources. Also, the WTRU may receive a grant indicating a frequency allocation and a time allocation for a scheduled transmission. Further, on a condition that the CI is received, the WTRU may interrupt the scheduled transmission. Additionally, the CI may indicate a subset of frequency resources of the set of reference frequency resources for each of a set of time symbols. Also, the WTRU may cancel the scheduled transmission on a condition that the subset of frequency resources of a set of time symbols overlaps with the frequency allocation and the time allocation for the scheduled transmission. In a further example, the first higher layer configuration may include an applicable maximum priority and the grant may include a priority index.
Patent CA-3142122-A1 (CA)
Title: Proximity-based model for indoor localization using wireless signals
Inventor: GOSHAL DEBARSHI PATANJALI
IPC: H04W64/00
Filed: 2020-06-02
Abstract: Systems and methods of using wireless signals to create a sensing infrastructure for tracking the location of a moving subject within residential or industrial indoor environments are provided. The changes and disruptions of wireless signals transmitted and received by a plurality of wireless devices are collected and analyzed to infer the position of a moving participant within a sensing area. More particularly, a proximity-based method that models and estimates the location of a moving participant within the sensing area with respect to a single or plurality of fixed position(s) of wireless devices is provided.
Patent CA-3142168-A1 (CA)
Inventor: EARLE JEOFFERY CHAD
IPC: B67C9/00
Filed: 2021-12-14
Abstract: A tripod assembly having three legs and being used for supporting a fuel can used to provide fuel to a heater. Each of the legs comprises at least two detachable leg pieces. An elastic tie down assembly is inserted within a recess in the legs and provides a tension to maintain the legs together in both their assembled and disassembled conditions.
Patent CA-3145828-A1 (CA)
Inventor: ALTSTEDDE KLEIN MIRKO
IPC: C09K5/12
Filed: 2020-06-18
Abstract: The invention relates to a container device for molten metal, comprising at least one receiving chamber (32) for a molten metal, the at least one receiving chamber (32) having a wall (34, 36) and a receiving space delimited by the wall (34, 36) for the molten metal. According to the invention, in order to provide such a container device which has a high thermal shock resistance, at least a region of the wall (34, 36) which comes into contact with the molten metal is produced from a fibre-reinforced SiC material or fibre-reinforced C-material as wall material.
Patent CA-3146986-A1 (CA)
Inventor: MENG QIN
IPC: C12N15/13
Filed: 2020-07-14
Abstract: Provided are antibodies that bind specifically to TIGIT or antigen binding fragments of the antibodies and a composition thereof. Also provided are a nucleic acid molecule coding the antibodies or the antigen binding fragments thereof, an expression vector and a host cell for expressing the antibodies or the antigen binding fragments thereof, and therapeutic and diagnostic uses of the antibodies.
Patent CA-3147590-A1 (CA)
Inventor: COOLEY KEN
IPC: C08L95/00
Filed: 2020-07-15
Abstract: L'invention concerne un mélange d'asphalte comprenant un liant d'asphalte, le liant d'asphalte comprenant au moins l'un parmi un liant d'asphalte vierge, un matériau de liant d'asphalte régénéré comprenant un revêtement d'asphalte (RAP), ou un matériau liant d'asphalte récupéré comprenant des bardeaux d'asphalte (RAS) et un agent anti-vieillissement ayant une valeur hydroxyle supérieure à environ 25 mg KOH/g.
Patent CA-3147953-A1 (CA)
Title: Substituted n-phenyl uracils, salts thereof and their use as herbicidal agents
Inventor: HEINEMANN INES
IPC: A01N43/54
Filed: 2020-07-20
Abstract: The invention relates to substituted N-phenyl uracils of the general formula (I) or salts (I) thereof, wherein the groups in the general formula (I) are as defined in the description, and to the use thereof as herbicides, more specifically for controlling weeds and/or weed grasses in crops of cultivated plants and/or as plant-growth regulators for influencing the growth of crops of cultivated plants.