baber/WOPTO huggingface dataset:
Patent PT-869727-E (PT)
Inventor: STACY PETER CHARLES
IPC: A61G7/057
Filed: 1996-11-25
Abstract: An alternating pressure pad which comprises at least two sets (1, 2) of inflatable cells, an air supply line (7a, 7b) to each set, a pump (8) to circulate pressurised air through a circuit including the sets of cells and to return air from the cells to the pump, valve means (6) for alternately causing inflation and deflation of each set, a sensor pad (3) in said circuit through which pressurised air is passed and detecting means (17) for detecting a reduction in air flow through the sensor pad which is below a predetermined level and for increasing air pressure in said sets of cells to restore the air flow above said predetermined level.
Patent PT-815848-E (PT)
Inventor: LION BERTRAND
IPC: A61K8/97
Filed: 1997-06-06
Abstract: Use of a graft copolymer with a skeleton (S) comprising a copolymer with a Tg of 0-30 degrees C, obtained by radical polymerisation or polycondensation, having a graft of a hydrophobic macromonomer (M) with a glassy Tg above 25 degrees C, for cosmetic and dermatological compositions, is new. Preferably (M) are hydrophobic hydrocarbons, hydrofluorocarbons, or fluorocarbons, with T'g above 25 degrees C, preferably 30 degrees C. (M) have a surface tension of 40 dyne/cm or less at 20 degrees C and an average molecular weight (summit of peak by steric exclusion chromatography) of 200-30000. Macromonomers (M) are chosen from oligomers which can be copolymerised by a radical route, with the monomers of the skeleton (S) and have a radical terminal carrying a double bond; oligomers with a radical terminal carrying a reactive function capable of interacting with (S) or its monomers (e.g. -OH, -NH2, -COOH, anhydride); or preferably oligomers which can be polycondensed with the skeleton monomers, with a radical terminal carrying a reactive function (e.g. diol, diamine, carboxylic diacid).
Patent PT-920426-E (PT)
Inventor: BEUME ROLF
IPC: A61K31/425
Filed: 1997-08-13
Abstract: PCT No. PCT/EP97/04435 Sec. 371 Date Feb. 26, 1999 Sec. 102(e) Date Feb. 26, 1999 PCT Filed Aug. 13, 1997 PCT Pub. No. WO98/08841 PCT Pub. Date Mar. 5, 1998Compounds having the formula (I): wherein R1, R2, R3, R4, R5 and n have the meanings given in the description. The compounds of formula (I) are selective inhibitors of phosphodiesterase IV.
Patent PT-941241-E (PT)
Title: Bordetella strain expressing the fha hybrid,
Inventor: CAPRON ANDRE
IPC: A61P11/00
Filed: 1997-10-09
Abstract: The invention concerns a Bordetella strain deficient in the production of toxin and expressing a hybrid protein comprising at least part of the filamentous hemagglutin (FHA) and at least part of a protein heterologous to FHA. The gene coding for the toxin has been eliminated, or at least partially deleted or mutated so as to produce an inactive toxin. This strain can be used as vaccine. The invention also concerns liposomes containing at least part of the FHA protein and at least one protein heterologous to the FHA protein, and the use of FHA for the stimulation of immune responses.
Patent PT-1088102-E (PT)
Inventor: GIBSON NEIL JAMES
IPC: C12Q1/6853
Filed: 1998-11-25
Abstract: A method for the detection of a target nucleic acid, which method comprises contacting template nucleic acid from a sample with (i) a signalling system and (ii) a tailed nucleic acid primer having a template binding region and the tail comprising a linker and a target binding region, in the presence of appropriate nucleoside triphosphates and an agent for polymerisation thereof, under conditions such that the template binding region of the primer will hybridise to a complementary sequence in the template nucleic acid and be extended to form a primer extension product, separating any such product from the template whereupon the target binding region in the tail of the primer will hybridise to a sequence in the primer extension product corresponding to the target nucleic acid, and wherein any such target specific hybridisation causes a detectable change in the signalling system, such that the presence or absence of the target nucleic acid in the sample is detected by reference to the presence or absence of a detectable change in the signalling system.
Patent PT-952218-E (PT)
Title: Single chain, multiple antigen-binding molecule, its preparation and use
Inventor: MULLER ROLF
IPC: C12N15/70
Filed: 1999-04-08
Abstract: Single-chain molecule (I) that binds multiple antigens comprises two variable domains of heavy immunoglobulin chains (VH), having specificities A and B and two variable domains of light chains (VL), also with specificities A and B. The domains are provided as two VH-VL constructs which are attached via a peptide (P). Any VH and VL may be replaced by their functional fragments. Independent claims are also included for the following: (1) nucleic acid (II) encoding (I); (2) vectors containing (II); (3) cells containing (II) or the vectors; (4) recombinant production of (I) by culturing these cells; (5) pharmaceutical composition containing (I), (II), the vectors or cells; and (6) diagnostic composition containing (I). ACTIVITY : Anticancer; antiviral; antibacterial; antimalarial; antiinflammatory. MECHANISM OF ACTION : Specific binding interaction.
Patent SG-43192-G (SG)
Title: Autonomous replication sequences for yeast strains of the genus pichia
IPC: C12N15/81
Filed: 1992-04-21
Abstract: Novel autonomous replication sequences which are capable of maintaining plasmids as extrachromosomal elements in host strains of the genus Pichia are provided. In addition, novel constructs including these DNA sequences, as well as transformed organisms therewith are provided. Processes for producing the DNA sequences and constructs of the invention, as well as method for isolating such sequences from any source, are provided.
Patent IE-40570-L (IE)
Title: Benzylamine derivatives
IPC: C07C209/52
Filed: 1975-01-22
Abstract: N-Cycloalkyl-benzylamine derivatives of the formula <IMAGE> in which R1 represents hydrogen or lower alkyl of 1 to 4 carbon atoms, R2 represents a cycloalkyl radical of a total of 7 to 12 carbon atoms which may be alkyl-substituted and may contain hydrocarbon bridges of 1 to 3 carbon atoms, R3 represents hydrogen, alkoxy of 1 to 4 carbon atoms, R4 represents hydrogen or alkoxy of 1 to 4 carbon atoms or halogen, and R5 represents alkoxy of 1 to 4 carbon atoms, methylene dioxy, ethylene dioxy, benzyloxy or halogen, and the physiologically tolerated salts thereof are disclosed as having diuretic and saluretic activity.
[US4024274A]
Patent IE-44217-L (IE)
Title: Making composite wrapping material
IPC: D21H19/08
Filed: 1977-01-25
Abstract: A method wherein a machine-foldable wrapper for chewing gum has a paper substrate metallized to give the appearance of continuous foil, the foil being made discontinuous to allow the paper to reach and maintain a moisture content which is in equilibrium with the ambient air. This prevents the wrapper from curling at the edges while in storage.[US4082594A]
Patent IE-890236-L (IE)
Title: Process for the preparation of chloranil
IPC: C07C46/06
Filed: 1989-01-26
Abstract: Process for the preparation of chloranil by oxidative chlorination of quinones or of hydroquinones with a mixture of hydrochloric acid and aqueous hydrogen peroxide, the introduction of the aqueous hydrogen peroxide taking place at a temperature above 60 DEG C.
Patent IE-44483-L (IE)
Title: Improvements in or relating to carbamyltriazole¹insecticides.
IPC: C07D249/12
Filed: 1977-03-01
Abstract: Insects of the orders Diptera, Coleoptera, Orthoptera and Lepidoptera are killed in the presence of living plants by applying to the locus of the insects an effective amount of a compound having the structural formula <IMAGE> in which R is 2-propynyl, allyl, 2-bromoallyl, 2-chloroallyl, 2-methylallyl, 1-methylallyl or 2,3,3-trichloroallyl and R' is tert.butyl, propyl, cyclopropyl, isopropyl or 1-methylpropyl.
[US4160839A]
Patent IE-840474-L (IE)
Title: Peptide analogues
IPC: C07K7/02
Filed: 1984-02-28
Abstract: PCT No. PCT/GB84/00063 Sec. 371 Date Oct. 31, 1984 Sec. 102(e) Date Oct. 31, 1984 PCT Filed Feb. 28, 1984 PCT Pub. No. WO84/03507 PCT Pub. Date Sep. 13, 1984.Peptides wherein an amide bond is replaced by nonhydrolyzable isosteric linkage are disclosed as thrombogenic inhibitors.
Patent IE-34102-L (IE)
Title: Smoking mixture.
IPC: A24B15/30
Filed: 1970-04-20
Abstract: 1298354 Tobacco substitutes IMPERIAL CHEMICAL INDUSTRIES Ltd 17 April 1970 [1 May 1969] 22270/69 Heading A2C [Also in Division C3] A smoking mixture comprises, as smokeproducing material, a solid condensate produced by acid or base catalysed condensation of a compound of the formula: R<SP>1</SP>COCH 2 CH 2 COR<SP>2</SP> (optionally produced in situ from a precursor thereof) wherein R<SP>1</SP> and R<SP>2</SP> which may be the same or different, each represents a hydrogen atom, or an alkyl, hydroxyalkyl or formyl group, the condensate being fabricated with the aid of a film-forming agent into a form from which a tobacco simulating material can be produced. In the examples condensates of succinaldehyde, acetonyl acetone, HCOCH 2 CH 2 COCOH, HCOCH 2 CH 2 COCH 2 OH and HCOC OCH 2 CH 2 COCH 2 OH are prepared and are mixed with sodium carboxymethyl cellulose, water, glycerol, potassium citrate, citric acid, ammonium sulphate, calcium carbonate and calcium citrate, and the resulting slurries are cast into films which can be cut into strips and shredded. Conventional additives such as flavourants and inert fillers may be included in the mixture.
[GB1298354A]
Patent IE-42655-L (IE)
Title: Increasing the growth rate of meat-producing animals
IPC: A23K1/16
Filed: 1976-03-15
Abstract: 1504151 Animal feeds containing quinone derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 9 March 1976 [17 April 1975] 15854/75 Heading A5B The growth rate of meat-producing domestic animals and the efficiency of the utilisation of animal feedstuffs is improved by orally administering to said animals a quinone derivative of the formula: wherein X is a guanidinoimino radical, optionally bearing one to three substituents on nitrogen selected from C 1-3 alkyl radicals and phenyl radicals, optionally substituted by halogen atoms; or a (1, 3-diaza-2-ene-heterocyclic)- 2-hydrazono radical; and Y is a guanidinoimino radical, optionally substituted, as defined for X above; a (3-nitroguanidino) imino radical; a semi-carbazono or thiosemicarbazono radical optionally substituted on N-4 by a carbamoyl radical, a benzyl radical, a C 1-3 alkyl or alkenyl radical, or a phenyl radical; or a 3-[4-(guanidinoimino) cyclohexa- 2, 5-dienylideneimino] guanidinoimino or 3-(4- semicarbazonocyclohexa-2, 5-dienylideneimino) guanidinoimino radical; or a dihydro derivative thereof; or a salt thereof; or a salt of a dihydro derivative thereof. A composition for use in the above method comprises a quinone derivative of formula I, or a dihydro derivative thereof or a salt thereof, or a salt of a dihydro derivative thereof together with a liquid or solid, edible non-toxic diluent or carrier.
[GB1504151A]
Patent IE-37527-L (IE)
Title: Electrical heater
IPC: C03B33/02
Filed: 1973-04-12
Abstract: 1420753 Heaters for float glass PILKINGTON BROS Ltd 11 April 1973 [21 April 1972] 18719/72 Heading ClM [Also in Divisions H3-H5] An electrical heater in an apparatus for manufacturing flat glass 28 on a molten metal bath 27 includes carbon heating resistors 8 enclosed in an elongated carbon box 1 to 6 from which they are insulated by supports with electrical connectors extending into the box from a terminal tab 26. The heaters are used in the float glass manufacturing process to heat directly the molten tin bath beside the glass sheet as in Fig. 4 and 10 and Figs. 3, 9,) not shown) or may be suspended in the roof of the reaction vessel (Figs. 11-14, not shown). In the embodiment described with respect to Fig. 10, heaters 39 maintain the temperature of the tin bath uniform whilst ,the surface of the glass is being modified by molten copper lead alloy 64 clinging to copper anode 60. Lead and copper ions migrate into the glass to be reduced later by hydrogen in the atmosphere above the glass giving a bronze appearance and heat rejecting properties.
[GB1420753A]
Patent IE-870713-L (IE)
Title: Genetic probes
IPC: C12Q1/68
Filed: 1987-03-18
Abstract: Test samples of genomic DNA may be characterized by the use of polynucleotide probes each of which is specific for an informative genetic locus. Such probes may be prepared by the use of probes which are capable of differentiating DNA by reference to more than one polymorphic minisatellite region or hypervariable locus. The polynucleotides and probes of the invention are of use for genetic identification purposes, paternity and maternity testing and particularly in forensic medicine.
Patent IE-45411-L (IE)
Title: Cephalosporin derivatives.
IPC: C07D501/04
Filed: 1977-04-04
Abstract: PURPOSE:Cephems or penams having a substituent at the 7-position or 6-position, useful as antibacterials, are prepared by the addition reaction of 7-sulfuenyliminocephem derivatives or 6-sufuenyliminopenam derivatives with an alcohol.
[JP52122390A]
Patent IE-810970-L (IE)
Title: Copolymer
IPC: C08F220/38
Filed: 1981-05-01
Abstract: Tridimensional cross-linked random copolymers, insoluble in water, containing in copolymerized form: (a) 25% to 98% by weight of N-[tris(hydroxymethyl)methyl]acrylamide or N-[tris(hydroxymethyl)methyl]methacrylamide, or a mixture of these two compounds. (b) 2% to 50% by weight of one or more monomers containing two or several polymerizable ethylenic double bonds and free from anionic or cationic functional groups, and (c) 0.1% to 50% by weight of one or more monomers containing a polymerizable ethylenic double bond and one or more mono- or di-substituted amino, pyrimidinyl, guanidyl, purinyl, quaternary ammonium, SO3H or SO3M groups, M being an alkali metal. These copolymers are utilizable, in the form of aqueous gels, as ion exchangers.
[US4452916A]
Patent FI-823237-L (FI)
Inventor: NEMET MIHALY
IPC: H01Q9/38
Filed: 1982-09-21
Abstract: A ground-plane antenna comprises a quaterwave resonant radiating rod (1) made of a hollow tube in which a central earthing rod (7) is arranged to form with the internal cylindrical wall of the radiating rod a line section short-circuited at the upper end. A further line section (16) open at the lower end is arranged in the extension of the short-circuited line section to form a combined tapped line section therewith having an electrical length substantially equal to the quarterwavelength, in which the combined line section is coupled with its tapping points in parallel to the input terminals (4, 5) of the antenna, whereby the susceptance represented by the combined line section is capable of compensating the changes of the antenna reactance within a fairly wide band.
Patent FI-843993-L (FI)
Inventor: NILSSON GOERAN
IPC: F24D19/10
Filed: 1984-10-11
Abstract: A device for adjusting the temperature supplied to the radiators in an automatic control equipment (7) of a heating boiler (1) comprises indicator means (12), such as light emitting diodes, for predetermined intervals of the outdoor temperature. The indicator means are arranged to be actuated by the temperature in the respective intervals. Each of the indicator means (12) is provided with an adjusting device (13), e.g. a slide potentiometer, comprising a slidable means (14), the position of which corresponds to a point of a graph of the supply temperature (tf) as a function of the outdoor temperature (tu). A variation of the position of the slidable means (14) results in a increase or decrease of the supply temperature.
Patent IE-36920-L (IE)
Title: Proteinaceous materials
IPC: A23L11/00
Filed: 1972-09-05
Abstract: 1367190 Proteinaceous foods H A HOFFMAN 4 Sept 1972 [17 Jan 1972] 40990/72 Heading A2B Artificial meat is made by leaching chunks of compacted fused vegetable material in water to dissolve soluble constituents and hydrate the chunks, and the chunks are dried prior to rehydration. Compaction is carried out for 1 to 5 minutes at at least 1800 p.s.i., preferably 2000 to 5000 p.s.i., at water boiling temperature. The initial shunks contain 7 to 9% of water, and the final dried chunks 6 to 8%. The vegetable protein material has a nitrogen solubility index of 30 to 70, and is obtained from soya bean, peanuts, lentils, mung bean, rape, cotton or sesame seed, alfalfa, or millet. The leaching is carried out for 1“ to 1¥ hours with water at at least 150‹F, preferably 190 to 212‹F, at atmospheric pressure and with a pH of 5 to 10. The chunks may be washed in water at 130 to 212‹F and the drying carried out with hot air. The chunks may be coated or impregnated with oleaginous material after drying. The size of the chunks may be 1/4 to 1 inch. The dried chunks can before or after rehydration be mixed with ground meat, rice, corn meal, other proteins, flavour enhancers, and other ingredients. The dried product may be packaged in multiwall bags or fibre drums, and the rehydrated product may be canned or frozen.
[GB1367190A]
Patent IE-33331-L (IE)
Title: Ergoline derivatives
IPC: C07D457/02
Filed: 1969-10-02
Abstract: 1,230,515. Ergoline derivatives. SOC. FARMACEUTICI ITALIA. 2 Oct., 1969 [7 Oct., 1968], No. 48397/69. Heading C2C. Novel ergoline derivatives of the formula wherein R is H or CH 3 ; R 1 is H when Y is halogen, NO 2 or alkoxy; R 1 is OCH 3 when Y is H, halogen, NO 2 or alkoxy; X is H or halogen; and n is 0 or 1 are prepared by reacting the appropriate 8#-aminomethylergolines with the corresponding pyridine carboxylic or pyridine-acetic acids in the form of their acid chlorides or mixed anhydrides. 1,6 - Dimethyl - 8# - aminomethyl - 10α- methoxy -ergoline is obtained by reducing with lithium aluminium hydride 1-methyl-10α-methoxy - dihydrolysergamide resulting from the methylation of 10α - methoxy - dihydrolysergamide which is made by reacting methyl 10α- methoxydihydrolysergate with ammonia. Pharmaceutical compositions, having hypotensive and adrenolytic activities and suitable for oral or parenteral administration, contain the above novel ergoline derivatives in admixture with solid or liquid vehicles or carriers.
[GB1230515A]
Patent IE-38183-L (IE)
Title: Anhydro-4-fluorocytosine nucleosides
IPC: C07H19/06
Filed: 1973-08-30
Abstract: Reaction of 5-fluorocytidine with the Vilsmeier-Haack reagent followed by treatment of the reaction mixture with water or a lower alkanol directly yields the previously unknown hydrohalide salts of 2,2'-anhydro-1- beta -D-arabinofuranosyl-5-fluorocytosine as crystalline solids. These compounds are useful as orally or parenterally active immunorepressive or anti-neoplastic agents and as intermediates in the preparation of other acid addition salts, such as the formate of the base compound.
[US3899482A]
Patent IE-861528-L (IE)
Title: Preparation of 3,5-dichloro-2-pyridone.
IPC: C07D213/64
Filed: 1986-06-09
Abstract: 3,5-Dichloro-2-pyridone is produced by chlorination starting from 6-hydroxynicotinic acid.
[US4681942A]
Patent IE-45535-L (IE)
Title: Power saw for cutting carcases
IPC: B23D51/18
Filed: 1977-07-25
Abstract: A butcher's meat saw has a housing from which extends a flat guide plate having an edge along which is slidable a blade reciprocated by an eccentric-type drive mechanism within the housing. Either the edge of the guide or the edge of the blade is formed with a groove and the other edge fits in this groove. One of these edges is furthermore formed with laterally opened notches so as to facilitate cleaning of the saw.
[US4114270A]
Patent IE-43526-L (IE)
Title: Pyridazinyl (thiono)(thiol) phosphonic acid esters.
IPC: C07F9/6509
Filed: 1976-08-20
Abstract: O-Alkyl-O-[6-substituted pyridazin(3)yl]-thiono) (thiol)alkanephosphonic acid esters of the formula <IMAGE> (I) in which X and Y each independently is oxygen or sulfur, R1 is alkyl with 1 to 6 carbon atoms, R2 is alkyl with 1 to 4 carbon atoms, R3 is alkoxy with 1 to 4 carbon atoms, alkynyloxy with 2 to 5 carbon atoms, alkylsulfonyloxy with 1 to 3 carbon atoms, monoalkylcarbamoyloxy with 1 to 3 carbon atoms, halogen, benzyloxy, benzoyloxy, phenoxy, or phenoxy carrying at least one substituent selected from halogen, nitro, cyano, -SO2CH3, -SO2CH2Cl, and alkyl, halogenalkyl or alkylthio, each with up to 3 carbon atoms, and R4 is hydrogen or alkyl with 1 to 3 carbon atoms, which possess insecticidal , acaricidal, nematicidal and fungicidal properties.
[US4140768A]
Patent IE-43545-L (IE)
Title: Blood-pressure lowering substance isolated from plants
IPC: C07D311/02
Filed: 1976-09-03
Abstract: EFFECTIVE SUBSTANCE FROM PLANTS BELONGING TO THE LABIATAE FAMILY of the disclosure: Extraction processes are described resulting in the isolation of a pharmacologically active substance from a plant of the Labiatae family. Chemical and physical properties of this compound are given in the specification. Because of its vasodilating and blood pressure lowering effect the compound is useful as a drug for the treatment of hypertension. (From CA1083589 A1) [GB1550410A]
Patent IE-792521-L (IE)
Title: Treating exit gases from a boiler plant
IPC: B03C3/013
Filed: 1979-12-28
Abstract: The present invention is directed to a method for selective purification of gases. The method comprises feeding an exhaust gas containing a solid impurity and a gaseous impurity to a separator. A substantial portion of the solid impurity is separated. Then, the partially-purified gas is fed to a spray dryer. That gas is sprayed with an absorption agent to separate gaseous impurities. Then, the further, partially-purified gas is fed to another separator to separate remaining solid impurity. An exhaust gas which is substantially free of solid and gaseous impurities and fly ash having a desired quality are recovered.
[US4301128A]
Patent IE-43784-L (IE)
Title: Production of chocolate pieces.
IPC: A23G1/30
Filed: 1976-11-29
Abstract: Chocolate pieces are manufactured from granulated, solid chocolate. Chocolate granules of a mean particle size of at least 1 mm are uniformly packed into tablet moulds and shaped into pieces under pressure at a temperature of below 17 DEG C. The process is particularly suitable for manufacturing chocolate, or chocolates, with a sculptured surface.
[GB1527240A]
Patent IE-892829-L (IE)
Title: Antihypertensive 3-piperidinyl-indazole derivatives
IPC: A61P25/18
Filed: 1989-09-01
Abstract: Novel antihypertensive 3-piperidinyl-indazole derivatives of formula   <CHEM>  wherein  R<1> is hydrogen or C1-6alkyl; R<2> is hydrogen; C1-6alkyl; substituted C1-6alkyl; optionally substituted phenyl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl or phenylcarbonyl, wherein phenyl may be substituted; R<3> and R<4> are hydrogen, halo, hydroxy, C1-6alkyloxy or C1-6alkyl;  Q is a bicyclic heterocyclic radical of formula <CHEM> the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are antihypertensive agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent NO-822531-L (NO)
Title: System for digital basisbaandtransmisjon i begge retningene til en to-traadsledning
Inventor: PANAROTTO GIANFRANCO
IPC: H04L5/14
Filed: 1982-07-22
Abstract: Systemet skal bli anvendt på digital basisbåndtransmisjon i begge retninger. på en totrådsledning og nærmere bestemt på en abonnentlinje (3). Denne be-. virker annullering av ekkoet, på grunn av signalet sendt av en dataterminal,. fra signalet mottatt ved selve terminalen, slik at informasjon og tidssignaler kan bli gjenvunnet. En fast linjeutjevning, konstruert for en hovedsambands-linjelengde, og en krets (CE) som annullerer støyen ved en korrelasjon mellom mottatte og sendte signaler blir benyttet. Den statistiske uavhengigheten j mellom den digitale strømmen i begge retninger blir tilveiebrakt ved bruk av en. linjekode av binærtypen.