baber/WOPTO huggingface dataset:
Patent FI-942107-A (FI)
Inventor: DOLLE ROLAND E
IPC: C07C233/47
Filed: 1994-05-06
Abstract: Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof: <CHEM>  wherein R1 is (CR5R6)n, (CR5R6)n-aryl, (CR5R6)n-heteroaryl, X-(CR5R6)n, X-(CR5R6)n-aryl or X-(CR5R6)n-heteroaryl wherein aryl and heteroaryl may be optionally substituted;     X is O or NR5;     R5 and R6 are independently H or lower alkyl;     R2 is H, halo, lower alkyl or (CR5R6)n-aryl;     R3 and R4 are independently H or alkyl; A is a D or L isomer of an amino acid selected from the group consisting of alanine, valine, leucine, isoleucine, proline, phenylalanine, glycine, tyrosine, methionine, asparagine, glutamine, aspartic acid, glutamic acid, lysine, arginine, histidine and  beta -thienylalanine;     Z is CH2 or O; and     n is 0-4; pharmaceutical compositions containing the compounds; and a method for inhibiting interleukin-1 beta  protease activity in a mammal utilizing the compounds and compositions.
Patent FI-950042-A (FI)
Inventor: KLIS FRANCISCUS MARIA
IPC: C07K19/00
Filed: 1995-01-04
Abstract: PCT No. PCT/EP93/01763 Sec. 371 Date Feb. 27, 1995 Sec. 102(e) Date Feb. 27, 1995 PCT Filed Jul. 7, 1993 PCT Pub. No. WO94/01567 PCT Pub. Date Jan. 20, 1994A method is provided for immobilizing an enzyme, comprising immobilizing the enzyme or a functional part thereof to the cell wall of a microbial cell using recombinant DNA techniques. The enzyme is immobilized by linking it to the C-terminal part of a protein that ensures anchoring in the cell wall. Also provided is a recombinant polynucleotide comprising a structural gene encoding an enzyme protein, a part of a gene encoding the C-terminal part of a protein capable of anchoring in a eukaryotic or prokaryotic cell wall, as well as a signal sequence, in addition to a chimeric protein encoded by the recombinant polynucleotide and a vector and a microorganism containing the polynucleotide. The microorganism is suitable for carrying out enzymatic processes on an industrial scale.
Patent FI-953525-A (FI)
Inventor: HOEOEK MAGNUS
IPC: C12N15/09
Filed: 1995-07-21
Abstract: The invention relates to a chemical synthesis process for preparing a protein or a polypeptide which binds fibronectin.
Patent FI-980839-A (FI)
Inventor: HILTUNEN KARI ERKKI
IPC: C07D319/12
Filed: 1998-04-15
Abstract: The invention relates to a technique for advantageously preparing lactide, which is well suited for polymerization, with water being removed from lactic acid, the lactic acid being oligomerized and the oligomer which has thus been prepared being depolymerized with the aid of heat, negative pressure and a catalyst. According to the invention, lactide is prepared in a plant which at least consists of a prepolymerization reactor 4, a remixing reactor 6, heated conduits 3, 5, 9, 11 and 12, a collecting vessel 10 for the lactide and a collecting vessel 19 for water, and by using any one of or some zinc compounds, titanium compounds, tin compounds or iron compounds, such as zinc stearate, for catalyzing reactions. The product is purified, if necessary, by washing with water or with a mixture of water and acetone. The resulting, purified lactide is directly suitable for preparing a plastic-like, biodegradable polymer, i.e. polylactide or polylactic acid, having a large molar mass. <IMAGE>
Patent FR-1329434-A (FR)
IPC: C08F8/50
Filed: 1962-07-24
Granted: 1963-06-07
Abstract: A wax composition contains a water-dispersible polyethylene wax and an amount (1-25% or more specifically 6-12% by weight on the composition) sufficient to inhibit changes in viscosity normally exhibited by the wax of a primary aliphatic saturated or unsaturated monohydric alcohol containing 4 to 20 carbon atoms, e.g. cetyl, stearyl, or oleyl alcohol or 2,2-dimethyltetradecanol. The wax may have a M.W. of 1000 to 6000, a density of 0.90 to 0.97, a ring-and-ball softening point of 90-112 DEG  C., and an acid number of 4 to 25.  In Example 7, stearyl alcohol is added to a degraded non-dispersible polyethylene wax prior to oxidation at 150 DEG  C. with oxygen.
Patent GB-112176-A (GB)
Title: Improvements in the Manufacture of Solid Rubber Tyres.
IPC: B29D30/02
Filed: 1917-01-22
Abstract: 112,176. Wood-Milne, Ltd., and Roberts, T. H. Jan. 22, 1917. Tyres, elastic, special apparatus for making.- The hard rubber base of a solid tyre is applied to the metal foundation band A in the form of a strip or strips E, the band A being supported on, and rotated by, the rollers B. Pressure is applied within the band by a roller C actuated by a screw d on a spring. The rollers B, C may be fitted with flanges or guides for the band A,
Patent GB-637443-A (GB)
Title: Phonograph apparatus
IPC: G11B17/16
Filed: 1947-01-13
Abstract: 637,443. Magazine gramophones. PHILCO CORPORATION. Jan. 13, 1947, No. 1104. Convention date, Jan. 12, 1946. [Class 40 (ii)] In a magazine gramophone, the horizontal movements of the pickup arm are controlled by a reciprocating cam structure, which forms part of a mechanism constructed' as a unit for the purpose of facilitating replacement &c. The vertical and horizontal movements of the pick-up arm 14 are effected by means of a cam-wheel 39 which is driven during an automatic cycle by the toothed part 28 of the turntable sleeve 38, via an intermediate stub combination-wheel 40, 42, the upper part 40 of which has a movable segment 47 which is normally held back against the tension of a spring 49a by a detent 48 until released by a solenoid-operated plunger 106. The circuit through the solenoid 104 is completed during normal automatic operation by means of a switch 107. During the playing of a record a finger 109 on an arm 110 attached to the pick-up arm shaft trails over the switchblade 108 which is depressed by the finger 109 when the pick-up arm reverses its direction of travel as it enters the final eccentric groove of the record. The solenoid circuit may also be completed by a manually-operated switch S when it is desired to reject a record. When it is desired to operate the gramophone manually, i.e. non-automatically, the switch S is made to break the circuit to the solenoid 104. When rotation of the camwheel 39 has been initiated, it completes one revolution, during which the pick-up arm is lifted by a lever 50 under the control of a cam-surface 55 on the underside of the camwheel 39. At the same time, the horizontal movements of the pick-up arm are controlled by an arm 22, Figs. 1 and 2, having a pin 22a which engages the cam-surfaces 71, 72, 73, 74, 78 and 75, Fig. 6, on a plate 57, which is made to slide backwards and forwards on rods 66, Fig. 1, under the control of a link 20, Fig. 2, connected to a rotating arm 61 on the cam-wheel shaft 43. As the plate 57 is moved inwardly the pin 22a is moved cotmterclockwise when it encounters the sloping surfaces 72, 73, so that the pick-up arm is swung outwardly to permit a new record to be dropped on to the turntable. As the plate 57 is returned outwardly, the pin 22a is moved clockwise by the sloping surface 78 to feed the pick-up to a position over the start of a record. The cam element 67 is mounted on rods 92 and is manually displaceable for 10-inch and 12-inch records by means of an upturned edge 98 on a sliding plate 96 moving on diagonal slots 100. A record-dispensing device 16 is provided in which an upper plate 23 unseats the lowermost record of the stack by means of an eccentric disc on the end of a rod 24 rotated by means of an arm 84, link 85 and a lever 82 pivoted at a point 83 and moved by a cam-wheel 86 mounted on an arm on the cam-wheel shaft 43. The record-dispensing device 16 is displaceable through an angle of approximately 180 degrees in order to accommodate 10-inch or 12-inch records and is coupled to the sliding plate 96 by a rod 95.
Patent GB-562109-A (GB)
Title: Improvements in and relating to the lifting and control surfaces of aircraft
IPC: B64C3/00
Filed: 1943-01-26
Abstract: 562,109. Aeroplanes. ENTWTSTIE, J. Jan. 26, 1943, No. 1277. [Class 4] An aeroplane has its lifting, steering and stabilizing surfaces freely pivoted about approximately fore and aft axes, the balance being maintained by an appropriate distribution of the lift and weight thereon. As described, the wings are pivoted to the machine, and the aeroengines and fuel tanks are mounted on the wings sufficiently far out to balance the proportion of the fuselage weight at the wing root. The wings may be pivoted about axes parallel to the plane of symmetry of the machine and either coincident with the chord line of 4 degrees below it as seen in side view. Alternatively, the axes may be coincident with the chord line as seen in side view, but rearwardly convergent in plan at angles to the plane of symmetry equal to the angle of incidence. The wings may be locked'' for landing, and in flight, limit stops may be provided and damping means may be used to control variation of dihedral angle. Flaps may be provided which are depressed as the dihedral increases. To maintain the dihedral angles on the two sides equal, the wings may be connected by cables through springs to a lever controlling a reversible electromotor by which trimming tabs on the wings may be actuated. Fig. 5 shows an aeroplane in which an engine is mounted on one wing and the cabin on the other, the rear stabilizing plane being asymmetrically arranged and a trimming tab provided on one wing.
Patent GB-565089-A (GB)
Title: Improvements in production of neutral calcium hypochlorite
IPC: C01B11/06
Filed: 1943-01-26
Abstract: 565,089. Calcium hypochlorite. MATHIESON ALKALI WORKS. Jan. 26, 1943, No. 1328. Convention date, Jan. 21, 1942. [Class 1 (iii)] Easily filtered slurries of neutral calcium hypochlorite are produced by simultaneously adding to a previously prepared slurry thereof, at rates which are substantially equivalent chemically, chlorine and a slurry of dibasic calcium hypochlorite, the liquid phase of the latter having a gravity of 30-47, preferably 40-44‹ Tw. The free lime content of the composite slurry is generally kept below 1.5 per cent by weight during the chlorination which is effected at 10-25, preferably 15-20‹ C. The dibasic slurry may be added continuously or intermittently to a neutral slurry, prepared initially by chlorination of lime or the dibasic compound until the free lime content is below 1.5, usually about 0.5 per cent by weight. The dibasic slurry may be prepared by chlorinating milk of lime, starting at room temperature and rising to 35-45‹ C. until substantially complete conversion when, if desired, part of the mother liquor may be drawn off after settling, and further chlorine added until the liquid phase has the desired gravity. The dibasic compound may be separated and resuspended. In a batch operation, when the reaction chamber is full, the addition of dibasic slurry is stopped, further chlorination to a lime content of 0.1-0.2 per cent effected if desired, and the neutral slurry removed leaving sufficient for the next operation. In continuous operation, four tanks may be used, milk of lime being chlorinated in the first at 30-40‹ C. to a gravity of 22-26‹ Tw., and further chlorinated in the next at 35-40‹ C. to a gravity of 40-47‹ Tw. The slurry is passed to the third tank containing the neutral slurry, while chlorine is introduced to keep the free lime content below 1.5 per cent, the product being finally reduced in lime content to, say, .05-.25 per cent by chlorine in the last tank, which may be cooled to, say, 0‹ C. Examples of batch and continuous operation are given.
Patent GB-149579-A (GB)
Title: Elbow check valve
IPC: F16K15/03
Filed: 1920-01-15
Abstract: 149,579. Superior Manufacturing Co., Woock, W. R., and Woock, H. J. Jan. 15,1920. Valves and valve seats, arrangement of.-An elbow check valve for a pump is provided with a removable valve seat member secured to the flange of the elbow and having the suction pipe of the pump secured to its lower end. The elbow 1<a> is provided with a flange 4 at its lower end, to which the flange 5 of the valve seat member is secured. The circular boss 6 forming the valve seat is rounded at 7 to prevent sand &c. lodging between the valve and the seat. The boss extends downwards at 8 and is threaded internally to receive the suction pipe of the pump. The flange 5 has a horizontal projection 10 on the side farthest from the pump, and an adjustment bolt 11 rests on a plate 12 to support partly the weight of the pipe and valve.
Patent GB-267657-A (GB)
Title: Improvements in or relating to rotary blowers, engines and the like
IPC: F01C1/44
Filed: 1926-01-18
Abstract: 267,657. Ellor, J. E., and Bargman, J. F. Jan. 18, 1926. Fixed-abutment type; driving pumps and blowers; valves, distributing.-A rotary blower or engine comprises a series of concavo-convex vanes 19, which are curved to the coacting surfaces of the casing and of rings 18 circling an eccentric drum 4, and which are attached at their inner ends to the rings 18 while their outer ends are attached to a pair of end discs 14 rotated together by a gear shaft 7 extending through the drum 4. The drum 4 is mounted on ball bearings 6 on the gear shaft 7, which is carried by ball bearings 8 in stationary cranks 9. The gear shaft 7 has spur wheels 26 meshing with spur wheels 25 on the bosses of the rotating end discs 14. The rotating end discs 14 are driven from the main shaft through spur gearing 30, 28, 27. A bye-pass and valve 31 connects the inlet and delivery ports.
Patent GB-120671-A (GB)
Title: Improvements in or relating to Apparatus for Measuring the Flow of Liquids.
IPC: G01F5/00
Filed: 1918-01-25
Abstract: 120,671. Brown, C., and Brown & Barlow. Jan. 25, 1918. Measuring-apparatus.-Liquid-meters comprising a tube a provided with a constant level supply chamber b, a calibrated orifice, an outlet f, and an indicating tube d with or without a constriction at its lower end, are provided with means for varying the capacity of the orifice. The means may consist of a cock with a number of orifices, or of two orifices e<1>, e<2>, a passage j leading from the orifice e' being adapted to be closed by a rod k located in a vertical pipe i. When the rod is lowered to shut off the orifice e<1>, a projection l enters a slot in the pipe i, and a scale h<2> carried by the rod is disposed close to the tube d. When both orifices are to be used, the rod is raised and rotated to bring a scale h<1> into position, the projection l then resting on the upper end of the tube i.
Patent GB-174594-A (GB)
Title: Improvements relating to carburetters
IPC: F02D9/00
Filed: 1922-01-17
Abstract: 174,594. Monseny, R., and Monseny, J. Jan. 25, 1921, [Convention date]. Void [Published under Sect. 91 of the Act]. Fluid - actuated valves. - Additionai air is admitted to an internal - combustion engine induction pipe at a rate dependent upon the velocitv of the mixture stream, by a valve e actuated by a laterally curved vane b pivoted at c and engaging a recess g in the valve. The vane is carried by lugs f in a casing a adapted to be secured between the flanges of the carburettor and induction pipe. The valve is loaded by an adjustable spring j, and has ports i adapted to register with ports h in the casing. The casing may be bevelled on one side to direct the mixture stream on to the vane, and be recessed on the other side to accommodate the vane when in its extreme position for opening the valve fully.
Patent GB-696639-A (GB)
Title: Improvements in or relating to tools for use in excavating and other operations
IPC: B25D3/00
Filed: 1950-01-19
Abstract: 696,639. Sockets. RICE, C. J. Jan. 19, 1951 [Jan. 19, 1950], No. 1463/50. Class 83 (iii). [Also in Group XXIII] In a tool comprising a shaft and a chuck for receiving a bit, the chuck permits the insertion and removal of the bit when in one position and traps the bit when in the inserted position by the rotation of a sleeve, means being provided to prevent the rotation of the bit to its freed position when the chuck is closed and further spring- urged means being provided which, when the chuck is closed, automatically and positively lock the sleeve in its closed position. The stem position 3 of a bit has radial projections 4 for engagement with a chuck 2 which comprises a body 5 welded to a tubular shaft 1 and having on its free end a screwed portion for engagement with a sleeve 6 which has a central aperture 7 with diametrally opposed side extensions to allow the passage of the projections 4. The body 5 has holes housing pins 13 attached to an axially movable ring 11 and spring-urged towards the sleeve 6. On screwing up the sleeve 6 the pins engage notches 18 in the sleeve, which notches allow rotation of the sleeve 6 for tightening but prevent rotation for loosening. To release the sleeve, the ring 11 is moved axially away from the body, withdrawing the pins from the holes and allowing the sleeve to be unscrewed. The pins may be provided in the sleeve and the co-operating holes in the body. The chuck may be used in a rotary tool, or in a percussive tool of the type described in Specification 647,500, [Group XXIII].
Patent GB-1404982-A (GB)
Title: Balustrades and railway sturctures
IPC: E04H17/16
Filed: 1972-01-13
Abstract: 1404982 Fencing BALOGLAZE Ltd 28 March 1973 [13 Jan 1972] 1577/72 Heading E1B In a balustrade comprising uprights 10 with vertical glazing channels 15, each of the upper ends of the uprights is joined to the rail 25 by a threaded stud 27 which passes through an intermediate block 30. The stud 27 has a head 26 and is screwed into a threaded bore 22 in the upright 10 by revolving the block 30 which has a slot 32 engaging a wing nut 31 screwed onto the stud. A neoprene washer 24 is interposed between the block 30 and the upright 10. The uprights are formed with vertically extending dovetail slot 21 which receive the ends of metal glazing members 20 and neoprene glazing strips 19 for reinforced glass panels 18. The ends of the uprights 10, of the glazing members 20, and of the glass panels 18, may be angled for use on a gradient. Sections of railing may be joined at corners by connectors 33 having dovetail projections 35 on their flanges 34.
Patent GB-690448-A (GB)
Title: Process for preparing higher alkylbenzenesulphonyl chlorides
IPC: C07C303/08
Filed: 1951-01-22
Abstract: The Specification comprises an improvement in or modification of the process claimed in the parent Specification, wherein the alkyl benzene sulphonic acids which are reacted with chlorosulphonic acid to form alkyl benzene sulphonic acid chlorides are substantially free from sulphonic acid.  The alkyl benzene sulphonic acids used are those in which the alkyl group contains at least three carbon atoms. In practice, the alkyl benzene sulphonic acids are obtained by sulphonation of the corresponding alkyl benzenes, conveniently at temperatures of 20-50 DEG  C., and the lower layer of waste sulphuric acid into which the coloured impurities generally go is separated from the alkyl benzene sulphonic acid which is then reacted with chlorosulphonic acid generally at temperatures below 20 DEG  C. to form the sulphochloride.  Preferably about 2.5 mols. of chlorosulphonic acid are used per mol. of alkyl benzene.  In examples: (1) an alkyl benzene having an alkyl radical of 12 carbon atoms (obtained by chlorination of a corresponding aliphatic hydrocarbon and subsequent condensation of the alkyl chloride with benzene followed by removal of the unreacted hydrocarbon) is sulphonated with sulphuric acid monohydrate.  After standing the lower sulphuric acid layer is drawn off and chlorosulphonic acid dropped into the upper layer.  The mixture is then stirred at 18-20 DEG  C. and some water is then added.  After standing the waste sulphuric acid is removed and the upper layer is then blown with air to remove dissolved hydrogen chloride, the residue being the alkyl benzene sulphonyl chloride; (2) as in (1) except that the alkyl benzene used has an average molecular weight of 236 and the sulphochlorination is effected at 18 DEG  C.
Patent GB-157921-A (GB)
Title: Cloth feed for heavy sewing machines
IPC: D05B27/02
Filed: 1921-01-10
Abstract: 157,921. Ehresmann, A., and Streibel, L. March 4, 1919, [Convention date]. Void [Published under Sect. 91 of the Act]. Sewing-machines; feed by dogs.-A feed tooth f is carried by a flat plate b sliding vertically in a plate a which slides horizontally in the bedplate. The plates are moved positively upwards: and to the left, respectively, by cams h, i, on the shuttle shaft. The plate b is moved downwards by the pressure on the work and the plate a is moved to the right by a spring k. A screw l determines the movement to the right and consequently the length of the stitch,
Patent GB-1197045-A (GB)
Title: A High Frequency Magnetron Apparatus for Use in Heating Ovens
Inventor: NODA TOMIMITSU
IPC: H03B9/10
Filed: 1969-01-10
Abstract: 1,197,045. Magnetron devices for heating apparatus; rectifying. TOKYO SHIBAURA ELECTRIC CO. Ltd. 10 Jan., 1969 [16 Jan., 1968 (4)], No. 1644/69. Headings H2F and H2H. In order to improve the operation of a magnetron 10 such as may be used in a heating oven the magnetron is supplied from an A.C. source 3 by way of a voltage multiplying circuit which includes a step up transformer 1 having a capacitor 9 and a diode 8 serially connected across the secondary winding 4 thereof, the secondary winding 4 being centre tapped at 5. With such an arrangement the magnetron 10 will oscillate for more than half the period of each cycle of the A.C. supply. In other embodiments the transformer secondary winding may be in two separate portions, two transformers may be used, a second serially connected diode and capacitor may be connected across the upper half of the secondary winding 4 the diode being oppositely poled to the diode 8 and finally the transformer may have a single secondary winding having connected thereacross a circuit including three diodes and three capacitors.