baber/WOPTO huggingface dataset:
Patent WO-2021067930-A1 (WO)
Title: Tumor-targeting polypeptide nanoparticle delivery system for nucleic acid therapeutics
Inventor: LU XIAOYONG
IPC: A61K47/64
Filed: 2020-10-05
Abstract: A novel nucleic acid delivery system is provided containing a linear histidine-lysine rich cysteine-containing peptide bearing a targeting function, and a four branched histidinelysine rich polypeptide. The delivery system includes nucleic acid such as an siRNA. The components form a stable nanoparticle complex through non-covalent interactions between the phosphates of siRNA and histidine/lysine of the polypeptide, with reduced toxicity, and selectively delivers the genetic material to cells. The targeting function enhances the efficiency of the nucleic acid delivery and transfection. Carrier molecules are provided that able to deliver a therapeutic molecule to a specific cell. The carrier molecule is modified with a targeting ligand capable of binding to specific receptors on the cell to be targeted. The therapeutic molecule is an siRNA, miRNA, or other oligonucleotide. The targeting moiety is a small molecule, peptide, or protein that shows an affinity for a receptor present on the cell to be targeted.
Patent WO-2021076748-A1 (WO)
Title: Cross reality system with wireless fingerprints
Inventor: SHVEKI GILBOA
IPC: G01S5/02
Filed: 2020-10-15
Abstract: A cross reality system enables any of multiple devices to efficiently and accurately access previously stored maps and render virtual content specified in relation to those maps. Both stored maps and tracking maps used by portable devices may have wireless fingerprints associated with them. The portable devices may maintain wireless fingerprints based on wireless scans performed repetitively, based on one or more trigger conditions, as the devices move around the physical world. The wireless information obtained from these scans may be used to create or update wireless fingerprints associated with locations in a tracking map on the devices. One or more of these wireless fingerprints may be used when a previously stored map is to be selected based on its coverage of an area in which the portable device is operating. Maintaining wireless fingerprints in this way provides a reliable and low latency mechanism for performing map-related operations.
Patent WO-2021087316-A1 (WO)
Inventor: GNANASAMBANDAM NATHAN
IPC: A61B5/00
Filed: 2020-10-30
Abstract: A method is disclosed for managing risk associated with a medical condition diagnosed for a plurality of patients in a population, the method including creating, using an artificial-intelligence engine of a cognitive intelligence platform, a population profile including a plurality of patient graphs associated with the medical condition and the plurality of patients in the population, wherein each of the plurality of patient graphs includes information pertaining to how engaged a respective patient is with managing the medical condition. The method further including determining, based on the population profile, the risk associated with the medical condition, wherein the risk includes a potential inadequacy in management of the medical condition. The method may also include performing an intervention based on the risk.
Patent WO-2021091867-A1 (WO)
Title: Methods and systems for homogenous optically-pumped vapor cell array assembly from discrete vapor cells
Inventor: SEIDMAN SCOTT JEREMY
IPC: G01R33/00
Filed: 2020-11-03
Abstract: A method of making an array of vapor cells for an array of magnetometers includes providing a plurality of separate vapor cell elements, each vapor cell element including at least one vapor cell; arranging the vapor cell elements in an alignment jig to produce a selected arrangement of the vapor cells; attaching at least one alignment- maintaining film onto the vapor cell elements in the alignment jig; transferring the vapor cells elements and the at least one alignment-maintaining film from the alignment jig to a mold; injecting a bonding material into the mold and between the vapor cell elements to bond the vapor cell elements in the selected arrangement; removing the at least one alignment maintaining film from the vapor cell elements; and removing the bonded vapor cells elements in the selected arrangement from the mold to provide the array of vapor.
Patent WO-2021101887-A1 (WO)
Inventor: GILSTRAP MARK
IPC: H02G3/22
Filed: 2020-11-17
Abstract: A flashing piece (10), having an outer portion (12), defining an opening and made of a first polymeric material and an inner portion (14), joined to the outer portion about the opening and extending across and covering the opening. The inner portion is made of a second polymeric material that is more flexible and elastic than the outer material and is in most places of a first thickness and further defines indented rings (16) wherein the second polymeric material is thinner than the first thickness, thereby enabling an installer to begin and propagate a tear about an indented ring.
Patent WO-2021137993-A1 (WO)
Title: Non-pneumatic tire having reinforced support structure and method of making same
Inventor: RIMAI BENJAMIN E
IPC: B60B9/26
Filed: 2020-12-03
Abstract: A method of making a non-pneumatic tire includes providing an inner ring of elastomeric material and an outer ring of elastomeric material, and arranging the inner ring and the outer ring such that the inner ring is substantially coaxial with the outer ring. The method further includes providing a plurality of sheets of reinforced elastomeric material and forming the plurality of sheets into a plurality of U-shaped sheets. The method also includes arranging the plurality of U-shaped sheets between the inner ring and the outer ring, and curing the inner ring, the outer ring, and the plurality of U-shaped sheets.
Patent WO-2022132157-A1 (WO)
Inventor: TRAINER BRANDON
IPC: G01N1/14
Filed: 2020-12-17
Abstract: A stackable environmental air sampling pump includes an external housing, an air pump inside the external housing, and a telescopic mast attached to the housing and configured to extend from the external housing. The external housing includes a recessed portion configured to receive a flexible tubing wrapped around the recessed portion and a handle on a first side of the external housing. The external housing further includes a first interlocking feature of a first type on a second side of the external housing, wherein the first interlocking feature is configured to connect to an interlocking feature of a second type. The external housing further includes a second interlocking feature of the second type on a third side of the external housing, wherein the second interlocking feature is configured to connect to an interlocking feature of the first type.
Patent WO-2021225640-A1 (WO)
Title: Systems and methods for low field mr/pet imaging
Inventor: SPOTTISWOODE BRUCE
IPC: G06T5/50
Filed: 2020-05-06
Abstract: Systems and methods of PET attenuation correction using low-field MR image data includes receiving a first set of image data and a set of low-field magnetic resonance (MR) image data. An attenuation correction map is generated from the low-field MR image data using a first trained neural network. At least one attenuation correction process is applied to the first set of image data based on the attenuation correction map to generate at least one clinical attenuation-corrected image.
Patent WO-2021159029-A1 (WO)
Inventor: WATKINS JEFFRY D
IPC: C07K16/28
Filed: 2021-02-05
Abstract: La présente invention concerne des anticorps anti-ROR1 et des procédés d'utilisation de ceux-ci dans le traitement de maladies et d'états liés à l'activité de ROR1, par exemple le cancer.
Patent WO-2021163032-A1 (WO)
Title: Measurement system, method, apparatus, and device
Inventor: WANG TENGHUI
IPC: G11C11/44
Filed: 2021-02-09
Abstract: Methods, apparatuses, and systems include acquiring initial environmental information corresponding to a superconducting qubit received from a superconducting circuit, the superconducting circuit being in an environment: determining first environmental information corresponding to the superconducting qubit in response to a quantum energy level of the superconducting qubit, being a first preset energy level; determining second environmental information corresponding to the superconducting qubit in response to the quantum energy level of the superconducting qubit being a second preset energy level; determining effective environmental information based on the first environmental information and the second environmental information; and determining arbitrary-order correlation information for identifying an environmental noise based on the effective environmental information and the initial environmental information.
Patent WO-2021163542-A1 (WO)
Title: Uplink collision handling
Inventor: HOSSEINI SEYEDKIANOUSH
IPC: H04W24/10
Filed: 2021-02-12
Abstract: The present disclosure generally relates to wireless communication. In some aspects, a user equipment (UE) may identify a collision between a first uplink transmission and a second uplink transmission, wherein the first uplink transmission is a high priority uplink transmission and the second uplink transmission is a low priority uplink transmission; and cancel the second uplink transmission based at least in part on a threshold delay period, wherein the threshold delay period is based at least in part on a UE processing capability and a minimum processing timeline capability, and wherein the second uplink transmission is canceled before a first overlapping symbol of the first uplink transmission and the second uplink transmission. Numerous other aspects are provided.
Patent WO-2021202006-A1 (WO)
Inventor: PHILLIPS ROSS A
IPC: F02M61/18
Filed: 2021-02-16
Abstract: Apparatuses and methods for fuel injection are disclosed. The apparatus includes an inner sac with one or more primary passages extending therefrom. The one or more primary passages inject fuel therethrough and comprising a first portion, a second portion, and a third portion, where the second portion is disposed between the first portion and the third portion and has a cross-sectional area smaller than that of both the first portion and the third portion. The apparatus also includes one or more secondary passages extending from an outer surface of the apparatus to fluidly couple with the second portion of the one or more primary passages. The one or more secondary passages inject air to form fuel-and-air mixture with the fuel injected from the one or more primary passages.
Patent WO-2021226027-A1 (WO)
Title: Graph neural network for multi-object detection and tracking
Inventor: RAMEZANI VAHID R
IPC: G06K9/00
Filed: 2021-05-04
Abstract: A method for multi-object tracking includes receiving a sequence of images generated at respective times by one or more sensors configured to sense an environment through which objects are moving relative to the one or more sensors, and constructing a message passing graph in which each of a multiplicity of layers corresponds to a respective one in the sequence of images. The method also includes tracking multiple features through the sequence of images, including passing messages in a forward direction and a backward direction through the message passing graph to share information across time.
Patent WO-2021236331-A1 (WO)
Title: Embedding data in address streams
Inventor: ROBERTS DAVID ANDREW
IPC: G06F15/167
Filed: 2021-05-05
Abstract: Techniques and devices are described for embedding data in an address stream on an interconnect, such as a memory bus. Addresses in an address stream indicate at least part of a location in memory ( e.g. , a memory page and offset), whereas data embedded in the address stream can indicate when metadata or other information is available to lend context to the addresses in the address stream. The indication of data in the address stream can be communicated using, for example, a mailbox, a preamble message in a messaging protocol, a checksum, repetitive transmission, or combinations thereof. The indication of data can be recorded from the address stream and may later be used to interpret memory traces recorded during a test or can be used to communicate with a memory device or other recipient of the data during testing or regular operations.
Patent WO-2021257201-A1 (WO)
Title: Scheduled entity behavior in full-duplex slot format
Inventor: ABOTABL AHMED ATTIA
IPC: H04W72/04
Filed: 2021-05-06
Abstract: Aspects of the disclosure relate to obtaining a duplex mode of a scheduled entity, selecting a downlink-uplink (DU) slot interpretation to be applied by the scheduled entity to a slot including a DU symbol based on the duplex mode of the scheduled entity, and transmitting the DU slot interpretation to the scheduled entity. The DU symbol may be configured to include a downlink transmission and an uplink transmission within a same carrier bandwidth. Other aspects relate to receiving a message, indicating that the slot is formatted with a DU symbol, selecting a DU slot interpretation to be applied to the slot including the DU symbol based on a duplex mode of the scheduled entity, and applying the DU slot interpretation to the slot. Other aspects, examples, and features are also claimed and described.
Patent WO-2022005625-A1 (WO)
Title: Speech synthesis and speech recognition
Inventor: TAN XU
IPC: G10L15/06
Filed: 2021-05-13
Abstract: Implementations of the subject matter described herein provide a solution for speech synthesis and speech recognition. In this solution, a Text to Speech (TTS) model and an Automatic Speech Recognition (ASR) model supporting at least one language are obtained. The TTS model and the ASR model are adjusted, based on a first set of paired data in a target language, to support the target language. The TTS model is optimized based on the first set of paired data and a first set of synthesized paired data in the target language generated by the ASR model while the ASR model is optimized based on the first set of paired data and a second set of synthesized paired data in the target language generated by the TTS model. As such, the solution can provide TTS and ASR models with high accuracy for languages lacking training data by using less training data.
Patent WO-2021236936-A1 (WO)
Title: Process for purifying hydrogen gas for use in fuel cells
Inventor: MORRIS WILLIAM
IPC: H01M8/0662
Filed: 2021-05-20
Abstract: The invention generally relates to a process for purifying a hydrogen gas for use in a fuel cell. The process involves taking a hydrogen feed stream from a high-pressure tank and passing it through a purifier comprising an adsorbent to provide a purified hydrogen stream which is sent to a fuel cell. A particular adsorbent which can be used is a metal-organic framework composition. The adsorbent can be housed in a device such as a canister or cartridge having an inlet and outlet port.
Patent WO-2021243319-A1 (WO)
Title: Biarylsulfonamides and pharmaceutical compositions thereof, and their use for treating fibrotic lung disease
Inventor: SWINDLEHURST CATHY A
IPC: C07C311/21
Filed: 2021-05-31
Abstract: Provided herein are a biarylsulfonamide, e.g., a compound of Formula (IA), and a pharmaceutical composition thereof. Also provided herein is a method of treating a fibrotic lung disease with a biarylsulfonamide, alone or in combination with an antifibrotic agent. Additionally, provided herein is a method of slowing the rate of decline in pulmonary function in a subject having a fibrotic lung disease with a biarylsulfonamide, alone or in combination with an antifibrotic agent.
Patent WO-2021247859-A1 (WO)
Inventor: OZBOYA KEREM
IPC: C07D471/04
Filed: 2021-06-03
Abstract: Disclosed are compounds useful in the treatment of neurological disorders. The compounds described herein, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological diseases.
Patent WO-2021257418-A1 (WO)
Title: 2-oxo-oxazolidine-5-carboxamides as nav1.8 inhibitors
Inventor: ARASAPPAN ASHOK
IPC: A61K31/4155
Filed: 2021-06-14
Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Na v 1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Na v 1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.
Patent WO-2021257548-A1 (WO)
Title: Treatment of neurological abnormalities using dynamic electroencephalography
Inventor: NUYTKENS PETER R
IPC: A61N5/06
Filed: 2021-06-15
Abstract: A method of treating a neurological disorder and/or disease includes positioning a stimulation apparatus on a patient. The stimulation apparatus includes an electrode array having a plurality of electrodes and an emitter array having a plurality of emitters. The method further includes measuring electroencephalography (EEG) signals of the patient with the electrode array. The method further includes emitting radiation into the patients brain from the emitter array based on the measured EEG signals in order to treat the neurological disorder and/or disease.
Patent WO-2022006313-A1 (WO)
Title: Automatic teach apparatus for robotic systems and method therefor
Inventor: GRACIANO JUSTO
IPC: G01B11/02
Filed: 2021-06-30
Abstract: An automatic teaching system for a substrate processing apparatus, the automatic teaching system comprising a frame having a workpiece load station with a predetermined load station reference location, a robot transport mounted to the frame and having a movable transport arm with an end effector having a predetermined end effector reference location, and a drive section driving the movable transport arm in at least one degree of freedom motion relative to the frame, a machine vision system including both at least one fixed imaging sensor and at least one movable imaging sensor removably connected to the frame and configured to image at least one target of the machine vision system, a load jig disposed for removable engagement with the workpiece load station, with both the at least one fixed imaging sensor and the at least one movable imaging sensor mounted to the load jig, the fixed imaging sensor.
Patent WO-2022015616-A1 (WO)
Inventor: CONSTANTINOU Jay
IPC: A43B5/02
Filed: 2021-07-12
Abstract: L'invention concerne un élément composite comprenant un textile et une couche d'hydrogel comprenant un matériau d'hydrogel qui est accouplé de manière fonctionnelle au textile, une partie de la couche d'hydrogel s'étendant à travers un premier côté du textile, et au moins partiellement dans un noyau du textile, mais ne s'étendant pas sur un second côté du textile. L'invention concerne également des structures de semelle et des articles de chaussures de sport incorporant l'élément composite, ainsi que des procédés de fabrication de tels éléments composites, structures de semelle et articles de chaussures.
Patent WO-2022056159-A1 (WO)
Inventor: TRAN HUY NGOC
IPC: A61B8/00
Filed: 2021-09-09
Abstract: Disclosed herein are ultrasound probes, ultrasound systems, and ultrasound methods with pressure measurement capabilities for detecting and determining if bodily tissue is over-compressed during ultrasound imaging procedure. For example, an ultrasound probe can include a probe body, an articulating probe head attached to the probe body, and a pressure-sensing device housed in an articulating area between the articulating probe head and the probe body. In another example, a method of the ultrasound probe includes placing the articulating probe head of the ultrasound probe on a skin surface of a patient and moving the articulating probe head of the ultrasound probe over the patient while ultrasound signals are emitted into the patient from the articulating probe head for ultrasound imaging. The method also includes monitoring for any measured pressure values induced on the patient by the articulating probe head of the ultrasound probe in excess of a threshold pressure value.
Patent WO-2022066990-A1 (WO)
Inventor: TSAI SHEN-FU
IPC: G06Q30/02
Filed: 2021-09-24
Abstract: Systems and methods for fast merging of panelist activity are disclosed. The system can maintain a plurality of panelist identifiers each stored with a respective plurality of offline content events, and identify, from the plurality of panelist identifiers, a subset of panelist identifiers that are stored with a respective offline content event that matches a target offline content event. The system can map each of the subset to a respective plurality of unique identifiers corresponding to virtual devices having virtual device attributes. The system can reduce, for each of the subset, the respective plurality of unique identifiers to a sketch that represents the respective plurality of unique identifiers. The system can combine the sketch of each of the subset of panelist identifiers into an aggregated sketch, and transmit the aggregated sketch to a computing device for analysis with an aggregated sketch representing online content events.
Patent WO-2022081700-A1 (WO)
Title: Corps céramique fritté multicouche et procédé de fabrication
Inventor: WALKER LUKE
IPC: C04B35/626
Filed: 2021-10-13
Abstract: Est divulgué un corps céramique fritté multicouche comprenant au moins une première couche comprenant au moins une phase cristalline de YAG, la ou les premières couches ayant au moins une surface; et au moins une seconde couche comprenant de l'alumine et au moins une de la zircone stabilisée et de la zircone partiellement stabilisée, la ou les surfaces de la ou des premières couches comprenant des pores, les pores ayant une taille maximale de 0,1 à 5 µm telle que mesurée par MEB et chacune de la ou des premières couches et de la ou des secondes couches ayant un coefficient de dilatation thermique (CTE), le CTE de la ou des premières couches et le CTE de la ou des secondes couches différant de 0 à 0,6 x 10-6/°C tel que mesuré conformément à ASTM E228-17. L'invention porte également sur des procédés de fabrication.
Patent WO-2022093604-A1 (WO)
Inventor: VAMOS CHRISTOPHER MICHAEL
IPC: E06B11/04
Filed: 2021-10-20
Abstract: A movable railing assembly includes a first railing segment having a first bogie and a first barrier coupled to the first bogie. The first bogie is configured to engage a track positioned below the first barrier and to facilitate movement of the first railing segment along the track, and the first barrier is configured to block access across the first railing segment. The movable railing assembly also includes a second railing segment having a second bogie and a second barrier coupled to the second bogie. The second bogie is configured to engage the track and to facilitate movement of the second railing segment along the track, and the second barrier is configured to block access across the second railing segment. Furthermore, the movable railing assembly includes a connector coupling the first railing segment to the second railing segment.
Patent WO-2022094477-A1 (WO)
Inventor: GUCCIONE ERNESTO
IPC: C07D213/81
Filed: 2021-11-02
Abstract: La présente invention concerne des procédés de traitement de tumeurs et de cancers ayant des voies de signalisation Wnt dérégulées avec des composés de formule (I) ayant la structure suivante (I) ou un stéréoisomère, un sel, un oxyde ou un solvate pharmaceutiquement acceptable de celui-ci, X étant un halogène et R étant un phényle substitué par un perfluoroalcane. L'invention concerne également un procédé de traitement d'une tumeur, qui comprend la mise en contact d'une tumeur comprenant l'EZH2 cytoplasmique avec un composé inhibiteur de kinases dans des conditions efficaces pour traiter la tumeur.