baber/WOPTO huggingface dataset:
Patent EP-0690835-B1 (EP)
Inventor: GODEK DENNIS M
IPC: C07C45/56
Filed: 1994-01-26
Granted: 1998-08-19
Abstract: A novel two-step reaction process for preparing 5-substituted-2-methoxybenzaldehyde compounds is disclosed wherein the substituent group is either isopropyl or trifluoromethoxy. The process involves (1) reacting a corresponding 4-substituted phenol compound with dimethyl carbonate in the presence of a tertiary-amine base to form the corresponding 4-substituted anisole compound, and (2) thereafter subjecting the latter intermediate product obtained in the first step to aromatic C-formylation on the ring with hexamethylenetetramine in the presence of trifluoroacetic acid, followed by hydrolysis, to ultimately yield the desired aldehyde compound. The two aromatic aldehyde compounds so obtained, viz., 2-methoxy-5-trifluoromethoxybenzaldehyde and 2-methoxy-5-isopropylbenzaldehyde, are known to be useful as intermediates that specifically lead to (2S,3S)-cis-3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-phenylpiperidine and (2S,3S)-cis-2-(diphenylmethyl)-N-((2-methoxy-5-isopropylphenyl)methyl)-1-azabicyclo(2.2.2)octane-3-amine, respectively. The latter final products, in turn, are both known to be useful in the field of medicinal chemistry as substance P receptor antagonists.
Patent EP-0686044-B1 (EP)
Inventor: HART CHARLES E
IPC: C12N15/02
Filed: 1994-02-17
Granted: 1998-09-02
Abstract: Methods of inhibiting intimal hyperplasia in the vasculature of mammals, including primates, are disclosed. The methods comprise administering to the mammal an anti-PDGF receptor antibody, such as an anti-PDGF-alpha receptor antibody or an anti-PDGF-beta receptor antibody. The methods are useful in reducing intimal hyperplasia due to, for example, vascular injuries resulting from angioplasty, endarterectomy, reduction atherectomy or anastomosis of a vascular graft.
Patent EP-0688215-B1 (EP)
Inventor: PIGGOTT JAMES R
IPC: A61K31/35
Filed: 1994-03-07
Granted: 2000-05-31
Abstract: Methods for the treatment of dermatitis are disclosed wherein 3,4-diarylchromans and their pharmaceutically acceptable salts are formulated into medicaments, including oral and topical medicaments, and are administered to a patient suffering from dermatitis.
Patent EP-0691814-B1 (EP)
Inventor: MORRIS R CURTIS JR
IPC: A61K33/10
Filed: 1994-03-29
Granted: 2002-06-26
Abstract: A combination of the following active ingredients for treating osteoporosis: (a) a pharmacologically-acceptable alkalinizing potassium salt which produces hydroxyl ions and is thereby capable of reducing the acidity of tissue fluids or urine and which is selected from the group consisting of potassium bicarbonate and potassium salts of carboxylic acids which are transformed to bicarbonate and thus alkalinize in vivo; and (b) a thiazide diuretic.
Patent EP-0695363-B1 (EP)
Inventor: FOOTE NICHOLAS PETER MARTIN
IPC: C12Q1/28
Filed: 1994-04-14
Granted: 1997-09-17
Abstract: An assay device comprises a tube, a removable top part and a bottom part, wherein an elongate member with a swab at its distal end is mounted on the top part, the top part includes a compartment containing liquid and partly defined by a first frangible membrane that can be ruptured to release the liquid into the tube, and the bottom part contains a reagent and is partly defined by a second frangible membrane that can be ruptured on movement of the bottom part relative to the tube. Reaction occurring in the bottom part can be observed through a window. This reaction may be of the type involving amplification of say, ATP, e.g. by providing AMP, glucose-6-phosphate (G6P), adenylate kinase, glucokinase and reagents that convert glucose (G) to give a color, whereby the following reactions occurAMP+ATP->2ADPG6P+ADP->ATP+G.
Patent EP-0692958-B1 (EP)
Inventor: MCSHANE JAMES E
IPC: A61Q17/04
Filed: 1994-03-30
Granted: 1998-05-13
Abstract: PCT No. PCT/US94/03258 Sec. 371 Date Nov. 13, 1995 Sec. 102(e) Date Nov. 13, 1995 PCT Filed Mar. 30, 1994 PCT Pub. No. WO94/22419 PCT Pub. Date Oct. 13, 1994Apparatus for simulating skin tanning comprises a receptacle containing a fluid comprising dihydroxyacetone, a receptacle containing a fluid comprising an amino acid, and dispensing means for simultaneously or sequentially providing desired amounts of dihydroxyacetone and amino acid.
Patent EP-0695471-B1 (EP)
Inventor: MUELLER ROLF
IPC: H02B1/38
Filed: 1994-04-19
Granted: 1997-07-23
Abstract: A switchgear panel (1) has a door arrangement (3) provided with a door lock (7) which has a closing element (23) with a closing shaft (32). A first drive dog (35), and also a second drive dog (42) axially movable on the closing shaft (32), are mounted on said closing shaft (32). The first drive dog (35) actuates a door locking bolt (27), whereas the second drive dog (42), according to its axial position, cooperates with a driver slide (30) which hangs down from a closing flap on an access opening (24) for a drive system (23). A sensor organ (31) actuates a driver fork (43) for the second drive dog (42) depending on the presence of switchgear (12) in the cabinet (10).
Patent EP-0703726-B1 (EP)
Inventor: PAYNE JOHN DAVID
IPC: A01N43/80
Filed: 1994-05-27
Granted: 1997-07-23
Abstract: Stable aqueous dispersions of 1,2-benzisothiazolin-3-one containing Xanthan gum which is substantially free from organic solvents.
Patent EP-0654981-B1 (EP)
Inventor: BURGER MICHAEL ALBERTUS
IPC: A61F5/56
Filed: 1994-06-09
Granted: 1996-12-11
Abstract: The Anti Bruxism Device is a device that stops or at least diminishes bruxism. Bruxism is a non-physiological parafunction that could damage teeth and molars, and affects the neuro-muscular system in a negative way. It could cause for example headaches, migraine like complaints, etc. To stop bruxism, our device uses a biofeedback system which detects (pathological) bruxism and stops it.
Patent EP-0712510-B1 (EP)
Inventor: YELLOWLEY IAN
IPC: G05B15/02
Filed: 1994-07-26
Granted: 1997-03-12
Abstract: Système de commande à opérations multiples constitué d'une pluralité de calculateurs asservis dont au moins certains sont des calculateurs d'axe dont chacun contrôle son fonctionnement respectif et reçoit des instructions décomposées en une pluralité d'actions multiples. On détermine l'état actuel Sc,N de chaque calculateur asservi et on le compare avec un état maximal absolu prédéterminé pour le calculateur asservi S¿ab,N(max)? en question, puis on détermine la variation maximale admissible de l'état δS¿a,N(max)? de chaque calculateur asservi respectif, et on transmet à tous les calculateurs asservis du système le signal d'état approprié correspondant basé sur la variation maximale admissible. Ensuite, chacun des calculateurs d'axe asservis lit tous les signaux d'état et identifie le signal d'état le plus élevé convenant à la totalité des calculateurs asservis, et chaque calculateur d'axe asservi procède aux variations incrémentielles de l'état δSN en fonction du S¿a,N(max)? le plus élevé convenant à la totalité des calculateurs asservis.
Patent EP-0746935-B1 (EP)
Inventor: STERN GEOFFREY
IPC: H04M3/533
Filed: 1994-07-18
Granted: 2003-05-28
Abstract: The present invention provides a recording and playback device used as a keepsake (20) capable of having a voice message recorded thereon and selectively played back comprising, on a single supporting structure (20') an integrated voice message recorded circuit (302) including means responsive to a control signal for storing a voice message in electronic form and means responsive to a control signal for playing back a stored message stored by said means for storing. Furthermore, it includes means (303) for reproducing a played back voice message in audible form as well as a connector (300) providing electrical connections to and from said device, wherein said control signal being provided to said circuit (302) for producing said control signal in place of any signal provided via said connector (300). The recording and playback device also consists of a manually operable control means coupled to said circuit (302) for producing said control signal in place of any signal provided via said connector (300). <IMAGE>
Patent EP-0717669-B1 (EP)
Inventor: GROSSMANN WALTER
IPC: B23Q1/01
Filed: 1994-08-13
Granted: 1999-04-28
Abstract: A NC automatic lathe has at least one carriage system (36) having an X, a Y and a Z axis that carries a tool revolver (38) designed as a so-called disk revolver (42) for working with lathe tools (74) and rotary machining tools (82). In order to reduce as much as possible the distance between a defined cutting plane for the turning process and the carriage system, the Y axis forms with the normal to the cutting plane (78) a relatively small acute angle (B), so that when the tool revolver (38) is rotated in a controlled manner around its axis (44), a rotatively driven machining tool (82) mounted on the revolver and located in its working position is swivelled with its axis of rotation (Wa) through an acute angle out of the cutting plane in the direction of the carriage system. The machining area of the machining tool (82) thus describes a movement with a component that extends in the minus direction of the Y axis.
Patent EP-0717756-B1 (EP)
Inventor: MASSE MICHAEL ALAN
IPC: C08F297/04
Filed: 1994-09-09
Granted: 1998-03-25
Abstract: A process for preparing a coupled asymmetric block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene which comprises: (a) adding sufficient anionic polymerization initiator to the vinyl aromatic hydrocarbon monomer to start polymerization of the vinyl aromatic hydrocarbon, (b) polymerizing the vinyl aromatic hydrocarbon for a time sufficient to form a first set of vinyl aromatic hydrocarbon blocks having a desired molecular weight, (c) adding sufficient anionic polymerization initiator to start polymerization of a second set of vinyl aromatic hydrocarbon blocks, (d) completing the polymerization of the vinyl aromatic hydrocarbon for a time such that the first set of vinyl aromatic hydrocarbon blocks continues to grow to the desired molecular weight and the second set of vinyl aromatic hydrocarbon blocks grows to a desired smaller molecular weight, (e) adding a conjugated diene and polymerizing it on the ends of the vinyl aromatic hydrocarbon blocks for a time sufficient to form vinyl aromatic hydrocarbon-conjugated diene arms of the desired molecular weight, and (f) adding a coupling agent and coupling the arms to form the asymmetric block copolymer.
Patent EP-0696810-B1 (EP)
Inventor: HOFSAESS MARCEL
IPC: H01H1/50
Filed: 1995-05-25
Granted: 1997-11-05
Abstract: A temperature-sensitive switch (10) for protecting electrical parts against excess temperature and/or excess current comprises a bimetallic switching device (14) which opens or closes its contacts in response to an excess temperature. Said switching device (14) is contained in a casing (17) having a pot-like bottom part (18) and cover (19). A first heating resistor (15) is connected in circuit with the switching device (14) such that it locks the switching device (14) in a self-holding manner when said switching device (14) is actuated in response to an excess temperature. A second heating resistor (16) is connected in circuit with said switching device (14) and produces heat in response to a current flow therethrough. When an excess current flows through the second heating resistor (16) the switching device (14) is actuated. Both, the first and second heating resistors (15, 16) are integrated in said cover (19) of said casing (17).
Patent EP-0719977-B1 (EP)
Inventor: GRAF WALTER
IPC: F16N11/10
Filed: 1995-11-30
Granted: 1999-02-17
Abstract: An automatic pressurizable lubricant dispenser has a vessel adapted to hold a supply of a fluent lubricant and having one side formed with an outlet adapted to be connected to a machine to be lubricated, a cover, and a cap fittable like a piston in the vessel and forming with the cover a substantially closed compartment holding a supply of a reactive liquid. The cover is formed with a seat opening into the compartment and extending along an axis and a removable partition closes the seat and segregates it from the liquid-holding compartment. A cartridge body fittable in the seat is movable therein between a partially inserted position and a fully inserted position and is formed unitarily of plastic with a cylindrical collar formed with a pair of diametrally opposite cutouts and having an outer end. The outer end moves from nonengagement with the partition in the partially inserted position to engagement through the partition in the fully inserted position. An element capable of reacting with the liquid and forming a gas is held by respective arms on the cartridge pivotal on the collar in the cutouts between holding and releasing positions. The arms each have an outer end formed with an inwardly directed retaining formation engaging the reactive element and holding same in the collar only in the holding position and an inner end engageable outwardly with the seat to pivot the respective outer end into the releasing position on movement of the body into the fully inserted position.
Patent EP-0670310-B1 (EP)
Inventor: RUTERBORIES KENNETH JAMES
IPC: A61K31/40
Filed: 1995-03-03
Granted: 1998-09-02
Abstract: This invention relates to bisulfite adducts of L-arginine aldehyde derivatives, the adducts having the formula Iwhere M, X and Y have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors and thromoembolic disorder agents.
Patent EP-0681178-B1 (EP)
Inventor: BAER THOMAS M
IPC: G06K9/00
Filed: 1995-05-02
Granted: 2001-07-04
Abstract: The apparatus and method of the present invention disclose a scanning imaging cytometer wherein an unprocessed biological fluid sample is reacted with a fluorescently-labeled binding agent. The reacted sample undergoes minimal processing before it is placed into a capillary tube. The sample is optically scanned and fluorescence excitation is recorded from a plurality of columnar regions of the capillary tube, each columnar region generally defined by the spot size of the excitation beam and the depth dimension of the capillary tube. A spatial filter of a sufficient pinhole diameter is selected to allow simultaneous volumetric detection of all fluorescent targets in each columnar region. <IMAGE>
Patent EP-0682011-B1 (EP)
Inventor: PHILIPPE MICHEL
IPC: A61K8/00
Filed: 1995-03-15
Granted: 1997-04-23
Abstract: New derivs. of serine are of the formula R-O-C(O)-NH-(CH2OH)CH-C(O)-O-R' (I), and/or their D or L optical isomers. R, R' = 8-30C hydrocarbon gps. 12 cpds. are specifically claimed, e.g. dodecyl-3-hydroxy-2-(N-hexadecyloxy-carbonyl) aminopropionate.
Patent EP-0710478-B1 (EP)
Inventor: DE SALVERT ARMELLE
IPC: A61K8/00
Filed: 1995-09-27
Granted: 1997-01-22
Abstract: Topical product contains a lipase and a precursor (I) of an active cosmetic or dermatological component which is an 2-25C ester having opt. branched, opt. unsatd. chain. An enzyme is pref. included in the prod. in amt. 0.05-30 (esp. 0.1-10)% of prod., and it is kept separate from ester on storage, either by physical separation in separate compartments of a package, or by microencapsulation. Ester pref. comprises 0.1-50 (esp. 0.5-10)% of the prod. and is pref. laurate, palmitate, stearate, cetylate, myristate, propionate, linoleate, acetate, butyrate, octanoate, oleate, cinnamate, ferulate, or mixts. Esters of vitamins and hydroxyketones esp. retinol, ascorbic acid, and dihydroxyacetone are esp. pref.
Patent EP-0670165-B1 (EP)
Inventor: VECCHIO GIANCARLO
IPC: A61K38/46
Filed: 1995-02-15
Granted: 2001-12-12
Abstract: The use of the seminal ribonuclease (BS-RNase) enzyme to develop pharmaceutic compositions for anti-metastatic therapy is described. <IMAGE>
Patent EP-0738137-B1 (EP)
Inventor: KREBBER BURGHARDT
IPC: A61K6/884
Filed: 1995-01-04
Granted: 2000-09-06
Abstract: Matériau dentaire emballé et prêt à l'emploi, durcissable aux rayons UV, aux rayons laser ou à la lumière, pour la réalisation d'obturations dentaires, d'inlays, d'onlays, de couronnes, de bridges, de dents artificielles, de dents à pivot, de prothèses dentaires et d'implants dentaires avec: a) un récipient imperméable aux UV et à la lumière dans lequel, b) un matériau est déposé de telle manière qu'il soit protégé à l'entreposage contre les effets des rayons UV et des rayons lumineux et qu'il puisse être retiré pour son utilisation, matériau qui comprend les éléments suivants: b1) une matrice polymérisable et/ou durcissable sous l'action des rayons UV, des rayons laser ou de la lumière pour produire une matière plastique dentaire thermodurcissable ou thermoplastique, matrice à laquelle est intégrée: b2) une charge microfine inorganique et dans laquelle est déposé, b3) un tissu sous forme de matte, de ruban ou de cordon ou un faisceau de fibres continues.
Patent EP-0737214-B1 (EP)
Inventor: SKELHORN DAVID A
IPC: C08J3/12
Filed: 1994-12-15
Granted: 2001-03-21
Abstract: A thermoplastic granule containing a high proportion of a particulate carbonate filler in a thermoplastic binder, for blending with an end product thermoplastic in which the carbonate filler is to be dispersed. The granule comprises at least 85% by weight of a particulate carbonate which is coated with one or more fatty acids having a carbon chain length of from 12 to 20 carbon atoms. The balance of the granule by weight comprises a thermoplastic polymeric binder which is solid at ambient temperature and is compatible with the end product thermoplastic in which the carbonate filler is to be dispersed. The polymeric binder is an amorphous polyolefins and/or a highly branched polyethylene wax. The PSD of the carbonate is selected to maximize packing.
Patent EP-0768967-B1 (EP)
Title: Procedure for the construction, making and remaking of extended road vehicles
Inventor: MLAKAR EMIL
IPC: B62D65/00
Filed: 1995-06-23
Granted: 1998-11-04
Abstract: A procedure for the construction, making and remaking of road vehicles in accordance with the invention makes it possible to increase the width of road vehicles, in particular standard-make road vehicles. The procedure in accordance with the invention is based on an asymmetrical extension whereby all vital parts of the driver's surroundings (steering, control assemblies and the parts of the driver's position) are kept unchanged, and need not be altered or remade. In this way the design, making and remaking are facilitated and an extension of the useful space is obtained. The procedure for the construction, making and remaking of extended road vehicles in accordance with the invention consists in keeping the vital assemblies (the driving and control assemblies) and the driver's working surroundings in their original dimensions and installation, while carrying out the extension by introducing, symmetrically or asymmetrically, or by a combination of both, an insert into the longitudinally extended vehicle. Such a construction, making and remaking keeps, essentially, all the vital parts of the original road vehicle (the control and driving parts remain unchanged). The steering wheel, the driver's surroundings with the seat and the distance between the wheels or the clamping of the front wheel remains, in any case, in the same relationship as in a series-produced, non-extended vehicle, regardless of the right- or left-hand installation of the steering wheel, or of the right- or left-hand installation of the engine.
Patent EP-0765188-B1 (EP)
Title: Oxidation catalyst
Inventor: GRIGOROVA BOJIDARA
IPC: B01D53/94
Filed: 1995-06-19
Granted: 1998-11-18
Abstract: A catalyst for use in an oxidation reaction comprises a porous alumina support in the form of pellets or powder, preferably powder. The porous alumina support has captured thereon a complex comprising gold, a transition metal selected from cobalt or manganese, and alumina, the concentration of gold on the support being less than 2 percent by mass of the catalyst, and the atomic ratio of gold to transition metal being in the range 1:10 to 1:200.
Patent EP-0770265-B1 (EP)
Inventor: AZUMA MASAMICHI
IPC: H01L27/115
Filed: 1995-07-10
Granted: 2002-03-27
Abstract: On effectue un échange de xylène (P44) sur une solution-mère de titamate de barium strontium (BST) d'une pureté supérieure à 99,999 % dissoute dans du méthoxyéthanol, et on ajoute un carboxylate d'un métal de dopant tel que du 2-éthylhexanoate de magnésium pour former un précurseur. Le précurseur est ensuite filé (P45) sur une première électrode (14), séché (P46) à 400 °C pendant deux minutes, puis recuit (P47) entre 750 °C et 800 °C pendant une heure environ pour former une couche (15) au BST correctement dopé. On dépose (P48) une deuxième électrode (16), on forme des motifs (P49) et on la recuit (P50) entre 750 °C et 800 °C pendant 30 minutes environ. On obtient un courant de fuite excellent si le dopant utilisé est du magnésium d'une molarité d'environ 5 %. Pour les autres dopants tels que Mg, Nb, Y, Bi et Sn la plage de molarité préférée pour le dopant est comprise entre 0,2 % et 0,3 %. La matière dopée au magnésium est utilisée comme couche intermédiaire (25, 27) entre les électrodes (24, 28) et la couche diélectrique (26) au BST d'un condensateur (20) au BST non dopé.
Patent EP-0785970-B1 (EP)
Inventor: DUNAWAY JAMES H
IPC: C09D133/06
Filed: 1995-10-04
Granted: 1999-04-28
Abstract: A method for polymerizing predominantly one or more acrylate and/or vinyl acetate monomers in the presence of a latex results in high solids dispersions of polymer particles with lower viscosities than traditionally observed. A significant wt. % of added monomers can be present in large particles, having nonspherical shapes. Some of the original latex particles are retained during the polymerization and these increase the solids content and lower the viscosity by packing in the interstices between large particles. The total polymer solids content can easily be varied from 70 to 92 or more wt. % which are higher than achieved in any previously reported aqueous polymerizations. The viscosities at very high solids contents become paste-like but the materials still are stable to storage and further handling without breaking the dispersion into an agglomerated polymer portion and released water. The dispersions are useful to form sealants, membranes, etc., either with or without other additives. A preferred use is as an acrylate water-based caulking compound where the high solids and thixotropy of the dispersion allows for formation of a water-based caulk with low shrinkage.
Patent EP-0724121-B1 (EP)
Title: Furnace
Inventor: VIESSMANN HANS DR
IPC: F24H1/30
Filed: 1996-01-18
Granted: 1999-04-07
Abstract: The component (G) forming the horizontal combustion chamber (1) is in the form of a steel plate housing with a water-conducting double casing (6) attached to front and back collectors (3,4). The combustion chamber is flange-mounted to the component (7) on the combustion chamber side. The combustion chamber side component, together with its successive components (9) positioned laterally to the longitudinal axis (8) of the combustion chamber, have an opening (11) matching the cross-section (Q) of the combustion chamber as far as the end component (10). The water-cooled wall of the combustion chamber has a light metal casing (13) in one or more pieces and covering the wall with which it is in thermal contact.
Patent EP-0786565-B1 (EP)
Inventor: BERGER XAVER
IPC: E04B1/48
Filed: 1996-12-23
Granted: 2003-03-19
Abstract: The equipment comprises a beam (11) contained in a housing (1) secured to the load (3) particularly a staircase. This is extracted from the housing so as to engage with a mounting (2) fixed to the wall (4). The housing can be joined to one or more reinforcing components, typically two curved ones (7) with straight sections extending below it. Distance pieces (9) can be provided on the housing for its alignment, also contact portions (5) brought to bear against the beam, and a component (13) accommodating a seal (14) between it and the mounting.