baber/WOPTO huggingface dataset:
Patent WO-2021127462-A1 (WO)
Title: Multiplexed assay using differential fragment size to identify cancer specific cell-free dna
Inventor: SINHA SUDHIR
IPC: C12Q1/686
Filed: 2020-12-18
Abstract: A retrotransposable element-based multiplexed quantitative polymerase chain reaction (qPCR) assay system to quantitate and distinguish cell free DNA integrity and concentration in blood, plasma, and serum as a measure of minimum residual disease, therapeutic effectiveness, neoadjuvant effectiveness in a patient having stage I, stage II, stage III, or stage IV cancer, and disease progression, thereby improving patient outcomes.
Patent WO-2021154725-A1 (WO)
Title: High creep recovery, low modulus polymer systems and methods of making them
Inventor: LIU PUWEI
IPC: C08F290/06
Filed: 2021-01-26
Abstract: Disclosed herein are methods of making an adhesive composition, the methods comprising providing a polyurethane acrylate and combining with a vinyl ether and co-curing the combination to form an adhesive composition, wherein after curing the adhesive composition has a modulus at -20 o C of less than about 10.0 mPa and a creep recovery of greater than about 50%. Also disclosed are the resulting adhesive compositions.
Patent WO-2021158638-A1 (WO)
Inventor: HAN GRACE G D
IPC: C07D231/38
Filed: 2021-02-03
Abstract: La présente invention concerne un composé de formule (I) : dans laquelle R 1 , R 2 , m, n, p, Q, X, Y, W, et "A" sont tels que décrits dans la description. La présente invention concerne également un procédé de préparation d'un composé de formule (I). L'invention concerne également un dispositif de stockage thermique comprenant un ou plusieurs composés de formule (I) et un procédé de stockage d'énergie.
Patent WO-2021162927-A1 (WO)
Title: Paging repetition, paging notification conflict and management in multiple wireless networks
Inventor: VAIDYA MAULIK V
IPC: H04W68/00
Filed: 2021-02-04
Abstract: According to one configuration, a wireless network environment includes a first wireless network and a second wireless network. A mobile communication device in the wireless network environment receives first paging notifications directed to the mobile communication device from a first wireless base station such as operated by a first wireless network service provider. The mobile communication device receives second paging notifications directed to the mobile communication device from a second wireless base station such as operated by a second wireless network service provider. Additional configurations include page repetitions and paging notifications. The wireless network environment provides improved paging over conventional techniques.
Patent WO-2021163619-A1 (WO)
Title: Methods and apparatus for diagnosis of progressive kidney function decline using a machine learning model
Inventor: NADKARNI GIRISH
IPC: G16C20/70
Filed: 2021-02-12
Abstract: In some embodiments, a non-transitory processor-readable medium can store code to be executed by a processor of a first compute device. The code can include code to cause the processor to receive, from a second compute device remote from the first compute device, a trained machine learning model. The code can include code to cause the processor to receive biomarker data and HSD of a diabetic human subject. The biomarker data can indicate a level of at least one of the following biomarkers: sTNFR-1, sTNFR-2, KIM-1, and ratios to one another of any of the preceding. The HSD can include a metabolic factor, a health-related factor, or a demographic-related factor. The code can include code to cause the processor to execute the trained machine learning model to generate an indication of whether the diabetic human subject will experience a progressive decline in kidney function over a period of time.
Patent WO-2021168437-A1 (WO)
Title: Flagging operational differences in agricultural implements
Inventor: BOGDAN CHRISTINA
IPC: G06F17/40
Filed: 2021-02-22
Abstract: Systems and methods for identifying operational abnormalities based on data received from an agricultural implement performing a task in an agricultural field are described herein. In an embodiment, a system receives time-series data captured from an agricultural implement performing an agronomic activity on an agricultural field, the time-series data including, for each of a plurality of timestamps, a location of the agricultural implement. The system identifies a plurality of passes in the time-series data and using the identified plurality of passes, identifies a plurality of location on the agricultural field in which the activity performed by the agricultural implement included a particular operational abnormality. The system generates a map of operational abnormalities for the agricultural field, the map of operational abnormalities including the plurality of locations on the agricultural field in which the activity performed by the agricultural implement included the particular operational abnormality.
Patent WO-2021173645-A1 (WO)
Inventor: O'MALLEY EDWARD
IPC: E21B23/00
Filed: 2021-02-24
Abstract: A method for preparing a borehole for fracturing including inserting an assembly comprising a fracture plug, a setting tool, a perforating gun and a controller into a borehole, delivering the assembly to a target location, automatically recognizing the target location, automatically setting the plug of the assembly at the target location, and automatically initiating the gun of the assembly to perforate the borehole.
Patent WO-2021173951-A1 (WO)
Inventor: ANDREUCCETTI CHRISTOPHER ALAN
IPC: B60L1/00
Filed: 2021-02-26
Abstract: In one aspect, an electric work vehicle includes a chassis extending in a longitudinal direction between a first end and an opposed second end, and a cab supported between the first and second ends of the chassis. The work vehicle also includes a work implement assembly positioned at the first end or the second end, and a storage compartment defining a storage volume extending in the longitudinal direction between the cab and the first end or the second end. Moreover, the electric work vehicle includes a battery module positioned within the storage compartment, and a drivetrain including an electric traction motor positioned within the storage compartment and configured to be operated via power supplied from the battery module. The electric traction motor is coupled to a transmission of the drivetrain to allow torque to be transferred from the traction motor to corresponding traction devices of the electric work vehicle.
Patent WO-2021178234-A1 (WO)
Inventor: URTASUN RAQUEL
IPC: G06F11/07
Filed: 2021-02-26
Abstract: Systems and methods of the present disclosure are directed to a method. The method can include obtaining simplified scenario data associated with a simulated scenario. The method can include determining, using a machine-learned perception-prediction simulation model, a simulated perception-prediction output based at least in part on the simplified scenario data. The method can include evaluating a loss function comprising a perception loss term and a prediction loss term. The method can include adjusting one or more parameters of the machine-learned perception-prediction simulation model based at least in part on the loss function.
Patent WO-2021174019-A1 (WO)
Inventor: RIGO FRANK
IPC: A61K31/7125
Filed: 2021-02-26
Abstract: Provided are compounds, methods, and pharmaceutical compositions for modulating SMN2 RNA and/or protein in a cell or subject. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom of a neurodegenerative disorder. Such symptoms include reduced muscle strength; inability or reduced ability to sit upright, to stand, and/or walk; reduced neuromuscular activity; reduced electrical activity in one or more muscles; reduced respiration; inability or reduced ability to eat, drink, and/or breathe without assistance; loss of weight or reduced weight gain; and/or decreased survival.
Patent WO-2021183889-A1 (WO)
Title: Well plate and petri dish fluid exchange plug
Inventor: TEBON PAYTON
IPC: C12M1/32
Filed: 2021-03-12
Abstract: The present invention provides a fluid exchange plug device configured for insertion into two or more wells of a multi-well plate, comprising: a plug body having an tipper surface and a lower surface; two or more sockets positioned within the plug body, each comprising a first opening, a second opening and a lumen therebetween, wherein two or more sockets, are accessible by the first opening on the upper surface of the plug body; two or more stoppers extending from the lower surface of the plug body having a first end and a second end, wherein the second end comprises at least one opening.
Patent WO-2021202092-A1 (WO)
Title: Méthode, système, et appareil de génération de modèles de traitement tridimensionnels dans le cadre de la chirurgie laser du glaucome
Inventor: HOLLAND GUY
IPC: A61F9/008
Filed: 2021-03-15
Abstract: Une méthode de traitement d'un volume cible du tissu oculaire d'un angle irido-cornéen d'un œil au moyen d'une source laser conçue pour appliquer de l'énergie optique suffisante pour altérer le tissu oculaire à chaque instance d'une pluralité d'instances durant un balayage d'un faisceau laser à travers un modèle de balayage, comprend le placement d'un foyer du faisceau laser à une profondeur initiale dans le volume cible du tissu oculaire; la détermination d'une ou plusieurs instances auxquelles empêcher l'application d'énergie optique suffisante pour altérer le tissu oculaire; et l'application d'énergie optique suffisante pour altérer le tissu oculaire au niveau de chaque instance de la pluralité d'instances durant un balayage du faisceau laser à travers le modèle de balayage, excepté pour la ou les instances déterminées, pour altérer ainsi un plan de traitement initial du volume cible du tissu oculaire à la profondeur initiale.
Patent WO-2021216235-A1 (WO)
Inventor: KOMOROSKI ADAM
IPC: B62D57/032
Filed: 2021-03-18
Abstract: A method of identifying stairs (20) includes receiving a plurality of footfall locations (128) of a robot (100). Each respective footfall location indicates a location where a leg (120) of the robot contacted a support surface (12). The method also includes determining a plurality of candidate footfall location pairs (212) where the candidate footfall location pair includes a first and a second candidate footfall location. The method further includes clustering the first candidate footfall location into a first cluster group (222) based on a height of the first candidate footfall location and clustering the second candidate footfall location into a second cluster group based on a height of the second candidate footfall location. The method additionally includes generating a stair model (202) by representing each of the cluster groups as a corresponding stair and delineating each stair based on a respective midpoint (MP) between each adjacent cluster group.
Patent WO-2021195378-A1 (WO)
Inventor: CHASE JACOB
IPC: F16L5/04
Filed: 2021-03-25
Abstract: A concrete structure with a corrugated bottom surface has a pipe passing through a passage in the structure. A fire stop assembly has a first portion with a split plate, split cage, split intumescent ring, split inner smoke ring and split outer smoke ring each fastened together to rotate together about a hinge on the split cage. The fire stop assembly has a second portion of the split plate, split cage, split intumescent ring, split inner smoke ring and split outer smoke ring fastened together to rotate together about a hinge. The first and second portions have free ends that spread apart to fit around the tube in an open position, and close around the tube in a closed position.
Patent WO-2021216801-A1 (WO)
Inventor: ZHANG YUHUA
IPC: A61K31/497
Filed: 2021-04-22
Abstract: The invention provides novel PEGylated interferon tau and therapeutic uses thereof. More particularly, the invention provides novel PEGylated interferon tau compositions, methods of their preparation, and methods of therapeutic use thereof in treating viral infections (e.g., coronavirus or flavivirus infections) and various other diseases and conditions.
Patent WO-2021222359-A1 (WO)
Inventor: XU QING
IPC: C07D495/04
Filed: 2021-04-28
Abstract: The subject matter described herein is directed to ferroportin inhibitor compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.
Patent WO-2021222577-A1 (WO)
Inventor: IUVONE PAUL MICHAEL
IPC: C07D209/58
Filed: 2021-04-29
Abstract: This disclosure relates to N-acetylserotonin derivatives that have neuroprotective properties for uses in treating or preventing traumatic brain injury, vision loss, neuronal cell ischemia, and retinal degenerative diseases. In certain embodiments, this disclosure relates to pharmaceutical compositions comprising the N-acetylserotonin derivative and a pharmaceutically acceptable excipient.
Patent WO-2021222674-A1 (WO)
Inventor: NI JANE
IPC: C12Q1/68
Filed: 2021-04-30
Abstract: Enantiomeric pairs of molecular wires comprised of oligomeric nucleic acids, wherein the oligomers of each wire possess identical nucleobase pair sequences and thus identical conductivity as between wires, are constructed and used to sense biological or chemical entities of interest at the cellular or molecular level. The oligomeric molecular wires conduct voltage inputs to sensing subsystem integrated circuitry, either from an electrostatic potential arising from a targeting agent (i.e., a capture agent) binding to an intended biological or chemical target molecule, or from an electrostatic potential associated with a reference molecule that has non-specific interactions with the environment. The chirality of the oligomers imparts selectivity to either the targeting agent or the reference molecule during assembly of the sensing subsystem.
Patent WO-2021236322-A1 (WO)
Title: Extrusion blow molded containers and processes for making same
Inventor: MIKA ALLEN T
IPC: B65D25/20
Filed: 2021-05-04
Abstract: Extrusion blow molded containers and processes for making same. In some embodiments, the container can include a body that can have a top, a bottom, and a sidewall connected to the top and bottom. The body can define a volume. A first section of the sidewall can include an opaque polymer composition and a second section of the sidewall can include a translucent polymer composition that provides a viewing window into the volume. The translucent polymer composition can include a first polyethylene copolymer derived from ethylene and at least one C 3  to C 20  α-olefin. The first polyethylene copolymer can have an I 2.16  (190°C/2.16 kg) of about 0.2 g/10 min to about 1 g/10 min, a melt index ratio of about 30 g/10 min to about 80 g/10 min, and a density of about 0.910 g/cm 3  to about 0.940 g/cm 3 .
Patent WO-2021226212-A1 (WO)
Title: Directional control of downhole component using nmr measurements
Inventor: PETER ANDREAS
IPC: G01V3/32
Filed: 2021-05-05
Abstract: A system for acquiring directional information about a geologic formation includes at least one directionally sensitive nuclear magnetic resonance (NMR) assembly disposed at a borehole string including the downhole component. The at least one NMR assembly includes at least one magnet configured to generate a static magnetic field and at least one coil configured to generate an oscillating magnetic field, the at least one NMR assembly configured to perform an NMR measurement of at least one sector of a formation region. The system also includes a processing device configured to receive NMR measurement data from the at least one NMR assembly. The processing device is configured to analyze the NMR measurement data to estimate a parameter of the sector, determine a direction of the downhole component based on the estimated parameter; and steer the downhole component according to the determined direction.
Patent WO-2021242541-A1 (WO)
Title: Overlay of dynamic spatial data on user interface for ablation by irreversible electroporation
Inventor: GUTBROD SARAH R
IPC: A61B18/14
Filed: 2021-05-14
Abstract: A system for ablation by electroporation including a catheter having electrodes, a display, and a controller. The controller is to generate, based on models of electric fields, graphical representations of the electric fields that can be produced using the electrodes, and overlay, on the display, the graphical representations of the electric fields and an anatomical map of a patient to aid in planning the ablation by electroporation, prior to delivering energy.
Patent WO-2021236477-A1 (WO)
Title: Storage system and method for storing and transporting medicament
Inventor: CHERN REY
IPC: F25D16/00
Filed: 2021-05-17
Abstract: A storage system for storing a drug includes a container, at least one passive cooling system, and an active cooling system. The container includes an interior volume to accommodate at least one drug. The at least one passive cooling system is disposed within the container and includes a phase change material. The active cooling system is operably coupled with the container and, when in an operational mode, maintains a desired temperature within the interior volume of the container.
Patent WO-2021242559-A1 (WO)
Title: Connectivity tracing using mixed reality
Inventor: BRUN QUENTIN
IPC: H04L12/24
Filed: 2021-05-18
Abstract: A machine vision system is provided including a camera, a user interface, a processor, and a system memory including computer program code stored thereon. The computer program code is configured, when executed by the processor, to receive an image including an asset identifier associated with a cable, extract asset equipment information from the asset identifier associated with the cable, generate a connectivity matrix based on the equipment information, and cause at least a portion of the connectivity matrix to be displayed on a user interface.
Patent WO-2022031363-A1 (WO)
Title: Cable modem and method thereof, computer readable medium and apparatus
Inventor: XIAO JING
IPC: H04L12/28
Filed: 2021-06-07
Abstract: A cable modem in communication with a cable modem termination system, configured to perform at least the following: during an operation phase of the cable modem, acquiring and storing damaged channel information indicating a damaged channel among a plurality of channels between the cable modem and the cable modem termination system which is detected during the operation phase; during an initialization phase of the cable modem, adjusting a scanning sequence of the plurality of channels according to the stored damaged channel information so as to cause the damaged channel to have the latest scanning order; and scanning the plurality of channels according to the adjusted scanning sequence to determine, among the plurality of channels, a channel for performing communication between the cable modem and the cable modem termination system.
Patent WO-2021252360-A1 (WO)
Title: Techniques for dynamic downlink and uplink quasi co-location relationship reporting
Inventor: RAGHAVAN VASANTHAN
IPC: H04L5/00
Filed: 2021-06-07
Abstract: Techniques for dynamic downlink and uplink quasi co-location (QCL) relationship reporting are disclosed. In an example, a base station may determine to change a QCL reporting state for a user equipment (UE), wherein the QCL reporting state is one of an active QCL reporting state or a restricted QCL reporting state. The base station may also generate an indication to indicate the change in the QCL reporting state to the UE in response to the determining the change in the QCL reporting state. The base station may also transmit, to the UE, the indication in response to the generating the indication.
Patent WO-2021257478-A1 (WO)
Title: Lte-nr relative timing indication
Inventor: ZHU XIPENG
IPC: H04W56/00
Filed: 2021-06-14
Abstract: Two or more base stations may share relative timing information. For example, a first cell may determining a cell level system frame number (SFN) and frame timing difference (SFTD) between the first cell and a second cell. At least one user equipment (UE) can be configured with dual connectivity with the first cell and the second cell. The first cell may send an indication of the cell level SFTD to the second cell via a backhaul with the second cell. The indication of the cell level SFTD may be the determined SFTD or a SFN reference time. In some implementations, the first cell may send a the SFTD measurement result and assistance information to the second cell via a backhaul to the second cell. The second cell may determine the cell level SFTD. In some implementations, a positioning network entity may determine the cell level SFTD.
Patent WO-2022026072-A1 (WO)
Inventor: RUSSO FRANK
IPC: G16B5/30
Filed: 2021-06-16
Abstract: The present disclosure relates to general and scalable techniques for modeling  in silico  the kinetics of systems of connected biochemical reactions. Particularly, aspects of the present disclosure are directed to deconstructing a reaction into a plurality of component steps, translating each component step into a set of rate equations to obtain a standard mathematical construct or model representing each component step, numerically integrating across the standard mathematical constructs or models using a system of ordinary differential equations to determine a contribution of each component step to a rate of change of molecules within reaction, and deriving a  in 
 silico  behavior of a system utilizing the reaction based on the contribution of each component step to the rate of change of the molecules within the reaction. The standard mathematical constructs or models may be parameterized based on an energy profile for the reaction inferred from machine-learning approaches.
Patent WO-2021263130-A1 (WO)
Inventor: NGUYEN HA
IPC: B01J37/12
Filed: 2021-06-25
Abstract: Methods for preparing molybdenum-based catalyst for epoxidation reactions using MPG sourced from a propylene oxide/styrene monomer (POSM) production process are described. Streams exiting from the POSM reactor are combined and separated to isolate an aqueous-based, MPG-containing purge stream from other recoverable byproducts of the POSM process. This MPG-containing purge stream is then used as is in the catalyst preparation of molybdenum-based catalyst for epoxidation. Alternatively, the MPG-containing purge stream can undergo additional purification treatments before being utilized in the catalyst preparation.
Patent WO-2023282919-A1 (WO)
Inventor: SHETH KETANKUMAR KANTILAL
IPC: E21B43/38
Filed: 2021-07-20
Abstract: A downhole gas separator and pump assembly. The downhole gas separator and pump assembly comprises a drive shaft; a first fluid mover having an inlet and an outlet; a separation chamber located downstream of the first fluid mover and fluidically coupled to the outlet of the first fluid mover; a gas flow path and liquid flow path separator located downstream of the separation chamber, having an inlet fluidically coupled to the separation chamber, having a gas phase discharge port open to an exterior of the assembly, and having a liquid phase discharge port; and a second fluid mover mechanically coupled to the drive shaft, located downstream of the first gas flow path and liquid flow path separator, and having an inlet fluidically coupled to the fluid phase discharge port of the first gas flow path and liquid flow path separator.