baber/WOPTO huggingface dataset:
Patent HR-P20100076-T1 (HR)
Inventor: JOLIDON SYNESE
IPC: C07D417/04
Filed: 2010-02-11
Abstract: Spojevi opće formule naznačeni time, da jeR1 halogen, -OR1', -SR1", cikloalkil, ciklički amid, heterocikloalkil, aril ili heteroaril s 5- ili 6- članova, koji sadrži jedan, dva ili tri heteroatoma, izabranih iz skupine koja se sastoji od kisika, sumpora ili dušika; R1'/R1" su vodik, C1-6-alkil, C1-6-alkil supstituiran halogenom, -(CH2)x-cikloalkil ili -(CH2)x-aril; R2 je -S(O)2-C1-6-alkil, -S(O)2NH-C1-6-alkil, NO2 ili CN; je aromatski ili djelomično aromatski biciklički amin koji može sadržavati jedan ili dva dodatna N-atoma, izabranih iz skupine koja se sastoji odi gdje jedan dodatni N atom prstena od aromatskog ili djelomično aromatskog bicikličkog amina može biti dostupan u obliku njegovog oksidaR3 do R10 su vodik, hidroksi, halogen, =O, C1-6-alkil, cikloalkil, heterocikloalkil, C1-6-alkoksi, CN, NO2, NH2, aril, heteroaril s 5 ili 6 članova koji sadrži jedan, dva ili tri heteroatoma, izabranih iz skupine koja se sastoji od kisika, sumpora ili dušika, -NH- C1-6-alkil, -N(C1-6-alkil)2, ciklički amid, -C(O)-ciklički amid, S-C1-6-alkil, -S(O)2-C1-6-alkil, C1-6-alkil supstituiran halogenom, C1-6-alkoksi supstituiran halogenom, C1-6-alkil supstituiran s hidroksi, -O-(CH2)y-C1-6-alkoksi, -O(CH2)yC(O)N(C1-6-alkil)2, -C(O)-C1-6-alkil, -O-(CH2)x-aril, -O-(CH2)x-cikloalkil, -O-(CH2)x-heterocikloalkil, -C(O)O- C1-6-alkil, -C(O)-NH-C1-6-alkil, -C(O)-N(C1-6-alkil)2, 2-oksi-5-aza-biciklo[2.2.1]hept-5-il ili 3-oksa-8-aza-biciklo[3.2.1]okt-8-il; R'i R" u skupini e) mogu tvoriti zajedno s -(CH2)4- prsten sa šest članova; ili suR, R', R" i R' neovisno jedan do drugog vodik ili C1-6-alkil; i gdje svaki aril-, cikloalkil-, ciklički amid, heterocikloalkil ili heteroarilne skupine s 5 ili 6 članova kao što je definirano za R1, R1', R1" i R3 do R10 mogu biti nesupstituirani ili supstituirani s jednim ili više supstituenata izabranih iz skupine koja se sastoji od hidroksi, =O, halogen, C1-6-alkil, fenil, C1-6-alkil supstituiran halogenom ili C1-6-alkoksi; n, m, o, p, q, r, s i t su 1 ili 2; x je 0, 1 ili 2; y je 1 ili 2; i njihove farmaceutski prihvatljive soli uz dodatak kiseline, uz iznimku (2-hidroksi-5-nitro-fenil)-(6-nitro-indazol-1-il)-metanona. Patent sadrži još 22 patentna zahtjeva.
Patent SI-1425028-T1 (SI)
Title: Use of il-18 inhibitors for the treatement or prevention of sepsis
Inventor: DINARELLO CHARLES A
IPC: A61K39/00
Filed: 2002-05-16
Abstract: The present invention provides a method of treatment and/or prevention of sepsis and other diseases characteristic to the Systemic Inflammatory Response Syndrone (SIRS), including severe sepsis, septic shock and sepsis related to cardiac dysfunction.
Patent SI-2025756-T1 (SI)
Title: Improved targeted DNA insertion in plants
Inventor: D HALLUIN KATHLEEN
IPC: C12N9/22
Filed: 2004-11-17
Abstract: Methods and means are provided to improve targeted DNA insertion in plants using rare-cleaving "double stranded break" inducing enzymes. Also provided are improved I-SceI encoding nucleotide sequences.
Patent SI-1706024-T1 (SI)
Title: Integrated diagnostic test system
Inventor: NEEL GARY T
IPC: A61B5/00
Filed: 2004-12-21
Abstract: A system for diagnostic testing may include a meter (130) for performing a diagnostic test on a sample applied to a test media (120), a container (110) configured to contain test media compatible with the meter, and a closure portion (140) for selectively closing the opening of the container. The system may further provide a sampling device (360), such as a lancet, operable connected to the container. The system may also provide mechanisms to disable a power source, an auto-on function of the meter, a diagnostic testing function of the meter, or other function of the meter when it has been determined that a triggering event has occurred. The triggering event may be, e.g., the expiration of a certain expiration of a certain time period, passage of a certain date, performance of a certain quantity of diagnostic tests, or use of a certain quantity of test media.
Patent SI-1727665-T1 (SI)
Title: Method and apparatus for the continuous production of fibre-reinforced plastic plates
Inventor: BEHRE KURT
IPC: B29C70/50
Filed: 2005-02-25
Abstract: A process for the continual production of a reinforced thermoplastic board material, comprises forming a fibre structure (2) using a fibre laying unit, forming one or more further fibre structures on top using a fibre supply unit (4c), and supplying a matrix material. The multi- layered fibre material (6) is then fed to a press in which the matrix material is warmed and/or pressed to a low viscosity fluid. The multi-layered fibre material is impregnated and the fibre structure is pressed into a board. A polyester cover layer, eg PET, is applied to the structure.
Patent SI-1813535-T1 (SI)
Title: Method and apparatus for recycling tea from scrap tea-bags
Inventor: ERDMANN PETER
IPC: B65B69/00
Filed: 2006-01-27
Abstract: Method involves firstly cutting up the faulty teabag into essentially parallel strips, which was filled with tea by a teabag production machine from a particular tea batch. The tea contained therein is sieved out from the teabag, tag and label parts. The tea sieved out is put back into the raw material pipe of the tea production machine to be handled again. Faulty tea bag is led to next step, where it is recognised and thrown away. Device has cutting tool with cutting cylinders meshing into one another on two parallel shafts, with first edge of cylinder acting as blade, second acting as counter blade; also has sieving tool.
Patent SI-2044673-T1 (SI)
Title: An electric motor
Inventor: TEKKALMAZ TEKIN
IPC: H02K1/00
Filed: 2007-07-20
Abstract: The present invention relates to a line start permanent magnet motor (1) having asynchronous properties at start-up and synchronous features in continuous operation, the rotor (3) of which comprises a core (4) formed of magnetic steel rotor laminations (L), more than one magnet (5) inserted into the core (4), more than one conductor bar (8) and end ring (10, 110) formed by injecting aluminum into the rotor slots (7) and wherein the magnets (5) are prevented to be displaced by means of the stoppers (12) disposed on the rotor lamination (L) arranged at the end of the core (4).
Patent SI-2573121-T1 (SI)
Title: Antibodies that bind IL-4 and/or IL-13 and their uses
Inventor: RAO ERCOLE
IPC: C07K16/00
Filed: 2008-10-14
Abstract: The present invention relates to a polyvalent bispecific antibody format which comprises a first polypeptide which is a constant heavy chain and a second polypeptide which is a constant light chain, wherein the first polypeptide is attached to two or more variable domains of a heavy chain and the second polypeptide is attached to two or more variable domains of a light chain. A preferred embodiment of the present invention refers to a tetravalent bispecific tandem immunoglobulin (TBTI). 
The polyvalent bispecific antibodies of the present invention resemble and keep the stability characteristics of an immunoglobulin molecule, expressing the heavy and light chains on two different polypeptides and incorporating the constant heavy regions and the constant light regions in order to stabilize the interaction between the variable heavy and the variable light domains and to force correct pairing of the corresponding VHNL. The present invention further refers to the uses of such polyvalent bispecific antibodies.
Patent SI-2459291-T1 (SI)
Title: Moveable chromatography column separator
Inventor: FALKENSTEIN ROBERTO
IPC: G01N30/00
Filed: 2010-07-28
Abstract: The current invention is directed to a chromatography column separator which separates the chromatography column in an upper chromatography column chamber and a lower chromatography column chamber, and which has a variable position within the chromatography column, and which is embedded by the chromatography material. The separator allows the replacement of the chromatography material in the upper chromatography column chamber without the need to replace the chromatography column material in the lower chromatography column chamber and it allows also the combination of two different chromatography materials with different chromatographical functional groups in one chromatography column.
Patent SI-2932970-T1 (SI)
Title: Antiviral therapy
Inventor: UNDERWOOD MARK RICHARD
IPC: A61P31/00
Filed: 2011-01-24
Abstract: The present invention relates to combinations of compounds comprising HIV integrase inhibitors and other therapeutic agents. Such combinations are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.
Patent DE-3587422-T2 (DE)
Inventor: FORTKAMP ELKE
IPC: C12P21/02
Filed: 1985-12-12
Granted: 1993-10-21
Abstract: DNA sequence encoding a hirudin-like protein having the biological activity of hirudin, a recombinant DNA molecule for cloning containing such DNA sequence, and a recombinant DNA process for preparing a hirudin-like protein having the biological activity of hirudin.
Patent DE-3686101-T2 (DE)
Inventor: SENGUPTA ASOK
IPC: E01F9/04
Filed: 1986-06-12
Granted: 1993-01-21
Abstract: Pavement-marking sheet materials of increased durability comprise a tough, abrasion-resistant top layer, preferably a polyurethane film having substantial flexibility but including trifunctional hydroxyl-terminated components of short molecular weight so as to obtain a significant degree of crosslinking, and a conformable underlying layer. A preferred underlying layer comprises unvulcanized elastomer precursor.
Patent DE-3687140-T2 (DE)
Inventor: HAWKINS GEOFFREY R
IPC: A61Q5/12
Filed: 1986-09-12
Granted: 1993-03-25
Abstract: A stable aqueous hair conditioning shampoo composition comprising an aqueous solution of hydrogen peroxide, a specific anionic surfactant, at least one nonionic surfactant, an acidic pH-producing agent and one or more hair conditioning components.
Patent DE-3750430-T2 (DE)
Inventor: CHIU KAI
IPC: D21F/
Filed: 1987-12-22
Granted: 1994-12-15
Abstract: A wire former comprising a structural framework, a headbox for holding and dispensing the pulp slurry, a breast roll, a couch roll, a forming fabric belt extending endless between the breast roll and the couch roll in a straight run, and drainage elements and suction devices underlying said straight run for extracting liquid from the slurry. The forming fabric is a multi-ply fabric, the uppermost ply being a self-sustaining weave with monofilament warp yarns of a given diameter interwoven with shute yarns, the lowermost ply being a weave with a series of generally ovate warp yarns having a vertical dimension generally equal to the diameter of the warp yarns of the uppermost ply, interwoven with shute yarns. The ovate warp yarns have a horizontal width in the shute direction substantially greater than their vertical dimension. Binder shute yarns interconnect the upper and lower plies by being interwoven with the upper and lower plies so as to be contained within the body of the multi-ply fabric.
Patent DE-3784861-T2 (DE)
Inventor: ABRAMS JEROME H
IPC: A61B8/06
Filed: 1987-06-04
Granted: 1993-07-22
Abstract: Blood flow in the aorta and pulmonary artery of a mammal, most typically a human, is measured volumetrically by a non-invasive, ultrasound apparatus. A piezoelectric ultrasound transducer (21, 22) is placed in the trachea (T) in great proximity to the aorta or pulmonary artery (A). Ultrasound waves are transmitted toward the path of flow of blood in the artery (A). Reflected waves are received. The average Doppler frequency difference between transmitted and received waves is measured. The cross-sectional size of the artery (A) is measured. Blood flow rate is determined from the measurements. The apparatus comprises a tracheal tube (11) or probe (10) with one or two transducers (21, 22) mounted at one end of the tube. The transducer(s) (21, 22) is (are) disposed to transmit ultrasound in selected directions. Electrical conductors (24-27) extend from the transducers (21, 22) the length of the probe. Inflatable balloons (29, 30) serve to urge the transducer(s) (21, 22) into contact with the inner wall of the trachea (T).
Patent DE-3850261-T2 (DE)
Inventor: QUEMADA HECTOR
IPC: H04B1/08
Filed: 1988-12-08
Granted: 1994-10-27
Abstract: The coat protein gene of cucumber mosaic virus strain c (CMV-C), the method of preparing it, its use to prepare transgenic plants and transgenic plants containing it are provided.
Patent DE-3852889-T2 (DE)
Inventor: ATKINSON ANTHONY
IPC: C12Q1/26
Filed: 1988-12-02
Granted: 1995-05-18
Abstract: A method for the estimation of a salicylate in a sample is characterized by enzymatically converting the salicylate to a catechol by the action of a salicylate mono-oxygenase enzyme on the salicylate in the presence of a reduced pyridine nucleotide, reacting the catechol with a compound selected from compounds of formula I or amine or phenolic compounds of formulae II, III or IV    <IMAGE>  Formula I   <IMAGE>  Formula II   <IMAGE>  Formula III
Patent DE-3874446-T2 (DE)
Inventor: STEAD JAMES ARNOLD
IPC: A61K9/22
Filed: 1988-07-20
Granted: 1993-04-15
Abstract: The invention relates to a controlled-release device consisting of a core comprising one or more water-soluble ingredients, at least one of these water-soluble ingredients being the ingredient which it is desired to release in a controlled manner, the abovementioned core being surrounded by a semi-permeable coating membrane in which one (or more) water-soluble particle(s) is/are dispersed, the number thereof being such as to give rise by dissolution, when the device is placed in an aqueous environment, to one or two pores extending through the coating and permitting communication between the core and the outside of the device.
Patent DE-3883506-T2 (DE)
Inventor: LESPADE PIERRE
IPC: C03C14/00
Filed: 1988-12-19
Granted: 1994-01-05
Abstract: Process for the manufacture, by a sol-gel route and compression with heating, of a composite material consisting of a fibrous reinforcement and of a vitro-ceramic or ceramic matrix based on silica. 
<??>The process of the invention is characterised in that the premature crystallisation of the matrix originating from the sol is delayed by the addition of a crystallisation-retarding agent to the sol. 
<??>This process makes it possible to obtain well-densified composite materials which have a residual porosity of less than 10%, this being done without adding new nucleating agents.
Patent TR-199900992-T2 (TR)
Inventor: LEENSLAG JAN WILLEM
IPC: C08G18/66
Filed: 1997-10-07
Abstract: Bir bükülmez köpügün hazirlanacagi sekilde köpük olusturma kosullari altinda bir poliizosiyanat ve iki farkli poliolün sokulmasi ve bu sekilde elde edilen bükülmez köpügün yükselme yönüne dik bir yönde ezilmesiyle bir bükülgen poliüretan köpügün hazirlanmasi için islem. -100 C ve +25 C arasinda hiç bir önemli cam geçis sicakligi göstermeyen ve 1.80-4.00 bir anizotropiye sahip olan bükülgen köpükler elde edilmektedir.
Patent TR-199902950-T2 (TR)
Inventor: III THOMAS WARD OSBORN
IPC: A61F13/15
Filed: 1998-06-03
Abstract: Emici araçlar, daha özellikle vücuda temas eden yüzeyi üzerinde bir yumusatici bilesim içeren, adet amaçli, idrar tutamama korumasi, veya her ikisi için bayan kullanicilar tarafindan dudak-arasinda kullanilan emici araçlar tarif edilmektedir. Dudak-arasi araç, kullanicinin dudak dokusunun kurumasini önlemek için ve yapinin kullanicinin dudak dokusuna sürtünmesini azaltmak için bir yumusatici bilesim ile ön-nemlendirilmis veya ön-isitilmis olan bir vucuda temas eden yüzeye sahiptir. Emici araç tercihen, kullanildiginda kullanicinin büyük dudagi iç yüzeyleri ile temasini koruyabilme özelligi vardir. Yumusatici bilesim, mineral yagi, vazelin ve/veya polisiloksan gibi bir plastik veya sivi yumusatici, aracin vücuda temas eden yüzeyi üzerinde yumusatici sabitlemek için bir yag alkolü veya balmumu gibi bir sabitlestirici madde, ve opsiyonel olarak kaplanmis yüzeyin islanabilirligini arttirmak için bir hidrofilik yüzey aktif içerir.
Patent DE-60021188-T2 (DE)
Inventor: KWON SE CHANG
IPC: C12N15/62
Filed: 2000-07-07
Granted: 2006-04-27
Abstract: A modified human granulocyte-colony stimulating factor (hG-CSF) is produced by culturing a microorganism transformed with an expression vector comprising a gene encoding a modified hG-CSF to produce and secrete the modified hG-CSF to periplasm, said modified hG-CSF being obtained by replacing at least one of the 1st, 2nd, 3rd and 17th amino acids of wild-type hG-CSF (SEQ ID NO: 2) with other amino acid.
Patent DE-60021255-T2 (DE)
Inventor: WATSON JEREMY
IPC: A61F5/453
Filed: 2000-04-05
Granted: 2006-04-27
Abstract: A tap for a urine drainage system, having a body, a lever and a barrel with a through bore which is mounted in the body for rotation between a position for through flow of liquid and a position which obturates fluid flow. The lever is mounted directly on the body for reversible rotation therearound, the arrangement being such that, on rotation of the lever, the barrel is movable between the two positions.
Patent DE-60025161-T2 (DE)
Inventor: YANG DACHUAN
IPC: A61L31/00
Filed: 2000-01-12
Granted: 2006-06-29
Abstract: The invention relates to a medical device, such as a stent or a balloon catheter that includes an expandable body portion which has an exterior surface that contacts a vessel wall during treatment. The medical device includes a first coating disposed over at least a portion of the exterior surface. The first coating includes a therapeutic substance that is intended for controlled release from the exterior surface. The medical device further includes a second coating overlaying at least a substantial portion of the first coating. The second coating includes a material that is generally impervious to elution of the therapeutic substance therethrough when the body portion is inserted into the vessel lumen. The material of the second coating is relatively inelastic so that the second coating fractures during expansion of the body portion to allow elution of the therapeutic substance through fissures formed in the second coating.
Patent DE-60025633-T2 (DE)
Inventor: KAKIUCHI SHOGO
IPC: B65G15/58
Filed: 2000-09-29
Granted: 2006-11-09
Abstract: A conveying apparatus of the invention is provided with a rotary disc portion (2) with a suction means which forms a slit (17) on an outer peripheral surface and sucks through the slit (17) so as to convey a conveyed article in a state of holding the conveyed article (11) by suction to both sides of the slit (17), and a linear conveying portion (8) with a suction means which sucks the conveyed article (11) riding over a pair of parallel conveying belts (52) through a gap between the conveying belts (52) so as to convey the conveyed article (11) in a state of holding the conveyed article by suction to the conveying belt (52), and has one end opposing to the outer peripheral surface of the rotary disc portion (2) so as to be capable of transfer the conveyed article (11). In accordance with the conveying apparatus of the invention, the inspecting apparatus and an aligning and supplying apparatus can execute a side surface inspection of a small article stably without requiring a lot of space. <IMAGE>
Patent DE-60037883-T2 (DE)
Inventor: HOGUE CHRISTOPHER V
IPC: A61K9/14
Filed: 2000-06-23
Granted: 2009-02-05
Abstract: Described is a carrier having a biomolecular interaction incorporated therein. The carrier is described as comprising a silica based glass and in an embodiment is a sol-gel derived glass. Also described are methods of incorporating biomolecular interaction within a carrier of the invention. Various types of biomolecular interaction are discussed as well as applications of carriers containing one or more biomolecular interactions.
Patent DE-60038026-T2 (DE)
Inventor: BEEBE STEPHEN J
IPC: C12R1/91
Filed: 2000-08-02
Granted: 2009-02-05
Abstract: A method for intracellular electro-manipulation is provided. The method includes applying at least one ultrashort electric field pulse to target cells. The ultrashort electric field pulse has sufficient amplitude and duration to modify subcellular structures in the target cells and does not exceed the breakdown field of the medium containing the target cells. The amplitude and duration of the ultrashort electric field pulse are typically insufficient to substantially alter permeability of the surface membranes of the target cells, e.g., by irreversibly disrupting the cell surface membranes. An apparatus for intracellular electro-manipulation is also provided. The apparatus includes a pulse generator capable of producing an ultrashort electric pulse output and a delivery system capable of directing the electric pulse output to target cells.
Patent DE-60106888-T2 (DE)
Inventor: HOLLAND MICHAEL
IPC: A61F7/10
Filed: 2001-03-23
Granted: 2005-11-24
Abstract: A device for relief of anal pain includes a rod having first and second opposite end segments (11, 12). The first end segment (11) is shaped for grasping in the hand. There is a substantially annular flange structure (13) between the first and second end segments, the flange structure having an external cylindrical surface on a flange (16). A cap (15) has an interior surface which defines a cavity for receiving the second end segment (12) of the rod, the interior surface of the cap being adapted to engage in sealing fashion the external cylindrical surface of the flange structure.
Patent DE-60110896-T2 (DE)
Inventor: KSANDER MICHAEL
IPC: C07D295/205
Filed: 2001-01-16
Granted: 2006-01-12
Abstract: Compounds of formula (I) wherein R2-C, R3-C, R4-C or R5-C may be replaced by N; and wherein n is 1, 2 or 3; R1 is aryl, heteroaryl or (aryl or heteroaryl)-lower alkoxy; R2, R3, R4 and R5 are independently hydrogen, lower alkyl, lower alkoxy, halo, trifluoromethyl or cyano; R6 is (i) or (ii) m is 1, 2 or 3; R7 is hydrogen, lower alkyl (aryl or heteroaryl)-lower alkyl, lower alkoxy, (aryl or heteroaryl)-lower alkoxy, hydroxy, oxo, lower alkylenedioxy or lower alkanoyloxy; W is O, S or NR8; R8 is -CORa, (iii), -COORd, -SO2Re, hydrogen, optionally substituted lower alkyl, aryl, heteroaryl or (aryl or heteroaryl)-lower alkyl; Ra, Rd and Re are independently optionally substituted lower alkyl, cycloalkyl, adamantyl, aryl, heteroaryl or (aryl or heteroaryl)-lower alkyl; Rb and Rc are independently hydrogen, cycloalkyl, optionally substituted lower alkyl, aryl, heteroaryl or (aryl or heteroaryl) lower alkyl; or Rb and Rc together represent lower alkylene; and pharmaceutically acceptable salts thereof; and enantiomers thereof; which are useful as inhibitors of microsomal triglyceride transfer protein (MTP) and of apolipoprotein B (apoB) secretion.
Patent DE-60111229-T2 (DE)
Inventor: FROST DOUGLAS ROBERT DAVID
IPC: E03D1/14
Filed: 2001-06-22
Granted: 2006-03-23
Abstract: A dual discharge valve for immersion in fluid, in a cistern includes a housing having an upper portion and a lower portion. An upwardly movable main valve assembly within the housing forms therewith a variable volume upper chamber and lower chamber. A first vent means is between the upper and lower chambers and an outlet leads down from the lower housing portion, which portion contains a seat for the main valve assembly at the entry to the outlet so that in the lowered position of the main valve assembly the outlet is blocked against the ingress of fluid. A central stem extends upwardly from the main valve assembly and is actuable by a first operating means remotely from the upper housing to raise the main valve assembly off its seat, the wall of the lower portion of the housing above the seat having apertures. On raising the main valve assembly immersion fluid can enter the outlet, the net upward force thereby causing it to rise to the top of the upper chamber and permit full flow of the immersion fluid through the outlet. A second operating means is actuable remotely from the upper housing, to separately raise the main valve assembly off its seat and then exert a downward force on the main valve assembly, so that at a predetermined intermediate water level, the main valve assembly re-seats.