baber/WOPTO huggingface dataset:
Patent JP-5095896-B2 (JP)
IPC: A61K47/42
Filed: 2000-10-11
Granted: 2012-12-12
Abstract: A suspension of vector particles (PV) based on polyamino acids and have a mean hydrodynamic diameter between 30 and 120 nm, and an insulin load factor of from 5 to 25% of associated insulin volume relative to the polyamino acid volume forming the vector particles. The polyamino acids are double-block polymers containing hydrophilic and hydrophobic monomers. The suspension may be prepared by copolymerizing N-carboxy anhydrides of hydrophobic monomers and precursors of hydrophilic monomers, in the presence of N-methyl pyrrolidone and methanol. The copolymer is optionally neutralized, subjected to dialysis, concentrated and water is eliminated to produce a solid powder, which can be suspended in a liquid to produce the colloidal suspension. Active principles such as insulin or vaccines are associated with the carrier particles to prepare special pharmaceutical products.
Patent JP-4182149-B2 (JP)
IPC: G01N27/04
Filed: 2001-01-23
Granted: 2008-11-19
Abstract: The invention provides homogeneous assay methods for nucleic acid hybridization, detection and evaluation. The assay includes obtaining signals from a test sample both before and during the application of a voltage to the test sample and correlating the signals, each of which is indicative of the binding affinity of the probe and the target to each other. The assay enables determining an extent of matching between the probe and the target, as the voltage can be calibrated so as to destabilize significantly any hybridization except perfectly complementary hybridization. The signals whose magnitude is correlated with binding affinity can be electrical conductance and/or fluorescent intensity. Preferably, both signal pairs are measured and compared so as to enhance the reliability of the assay. The assay can detect specific hybridization between single-stranded probes and non-denatured double-stranded targets to form triplexes, thus obviating the need to denature the targets. The assay methods can also be applied to duplex hybridization complexes.
Patent JP-4881532-B2 (JP)
IPC: C07D217/06
Filed: 2001-04-25
Granted: 2012-02-22
Abstract: Compounds having formula (I) are inhibitors of urokinase and are useful in the treatment of diseases in which urokinase plays a role. Also disclosed are urokinase-inhibiting compositions, methods for the preparation of urokinase-inhibitors, and a method of inhibiting urokinase in a mammal.
Patent JP-5247965-B2 (JP)
IPC: H01F27/24
Filed: 2001-04-26
Granted: 2013-07-24
Abstract: A bulk amorphous metal magnetic component has a plurality of laminations of ferromagnetic amorphous metal strips adhered together to form a generally three-dimensional part having the shape of a polyhedron. The component is formed by stamping, stacking and bonding. The bulk amorphous metal magnetic component may include an arcuate surface, and an implementation may include two arcuate surfaces that are disposed opposite each other. The magnetic component may be operable at frequencies ranging from between approximately 50 Hz and 20,000 Hz. When the component is excited at an excitation frequency "f" to a peak induction level Bmax, it may exhibit a core-loss less than "L" wherein L is given by the formula L=0.0074 f(Bmax)1.3+0.000282 f1.5(Bmax)2.4, said core loss, said excitation frequency and said peak induction level being measured in watts per kilogram, hertz, and teslas, respectively.
Patent JP-4523222-B2 (JP)
IPC: H04Q7/32
Filed: 2002-04-02
Granted: 2010-08-11
Abstract: Methods for producing immunoglobulins and in particular anti-D immunoglobulin substantially free of prion and virus, and product resulting therefrom. Specifically provided are methods for nanofiltration of the anti-D immunoglobulin in high ionic strength buffer and with excipient such as polysorbate 80. Additional steps include diafiltration to concentrate the anti-D protein and reduce the concentration of excipient present.
Patent JP-3781115-B2 (JP)
IPC: B41J19/20
Filed: 2002-08-22
Granted: 2006-05-31
Abstract: <P>PROBLEM TO BE SOLVED: To achieve more appropriate printing quality by adequately adjusting a PG without a user's operation in a printer that adjusts the PG in multiple stages.  <P>SOLUTION: A carriage guide shaft 5 is pivotally supported on a position eccentric from a rotational center of a lever-like member 21, and then the PG is varied by the rotation of the lever-like member 21. A first rotating means for rotating the lever-like member 21 has a link rod 23 operating by cooperating with a paper discharge stacker 11 and rotates in a large angle by the reciprocating operation of the link rod 23. A slot hole 23a is formed on the tip portion of the link rod 23 and a projection 22 is inserted into the slot hole 23a with a play. A second rotating means for rotating the lever-like member 21 has a cam gear 25 and can rotate in a small angle in the range of relative movement of the projection 22 in the slot hole 23a by the rotation of the cam gear 25.  <P>COPYRIGHT: (C)2004,JPO
Patent JP-4298238-B2 (JP)
IPC: H01L21/68
Filed: 2002-08-27
Granted: 2009-07-15
Abstract: <P>PROBLEM TO BE SOLVED: To provide a substrate treatment apparatus that can efficiently determine whether a substrate under treatment at that time is nonconforming or not even if an abnormality occurs in the operation of a treatment section.  <P>SOLUTION: When abnormality is detected in the operation of one of treatment units (step S3) while treatment is performed (step S2), the substrate that is treated in the treatment unit at that point is set to be a substrate to be inspected (step S4), and a series of continuous process treatment for the substrate to be inspected continue (step S5). Meanwhile, a host computer specifies inspection details according to contents of the abnormality in operation (step S6). The substrate treatment apparatus inspects the substrate to be treated where a series of treatment are completed according to the inspection contents (step S7), and a substrate where the inspected result is nonconforming is accommodated in a carrier exclusive for nonconforming substrates (step S10).  <P>COPYRIGHT: (C)2004,JPO
Patent JP-3999658-B2 (JP)
IPC: B05B11/00
Filed: 2001-11-23
Granted: 2007-10-31
Abstract: A foam forming unit particularly suitable for a liquid container, comprising a pump for liquid and a pump for air, which are each provided with an inlet and an outlet, the foam forming unit further comprising a mixing chamber which is in communication with the outlet of each pump, a dispensing part provided with an outflow channel with a foam opening, the channel being in communication with the mixing chamber, and valves in respectively the inlet and the outlet of each pump for drawing in respectively delivering air and liquid, wherein one or more valves are formed integrally with the air pump or liquid pump into a single construction element.
Patent JP-3947467-B2 (JP)
IPC: B41M5/50
Filed: 2001-12-06
Granted: 2007-07-18
Abstract: An ink-jet printing process including the steps (a) and (b) in any order or simultaneously: (a) applying an ink to a substrate by means of an ink-jet printer in a localized manner to form an image on the substrate; and (b) applying to the substrate a composition including a liquid medium and a poly(C<SUB>3-18</SUB>-hydrocarbyl monoguanidine) or a salt thereof by means of an ink-jet printer. also a substrate printed by means of this process, compositions including poly(C<SUB>3-18</SUB>-hydrocarbyl monoguanidines), sets of liquids for use in ink-jet printing and ink-jet printer cartridges. The process avoids the need for expensive special papers previously used for ink jet printing.
Patent JP-4236465-B2 (JP)
IPC: A61F11/08
Filed: 2001-11-16
Granted: 2009-03-11
Abstract: The present invention provides an apparatus for determining in situ the acoustic seal provided by an in-ear device of a hearing protection/aid nature inserted into the ear canal of an individual. The in-ear device having a sound bore with an environment opening and an ear opening outside and inside the ear canal respectively, the environment opening is adapted to be removably engaged by a remote device such as a sound measurement device, a filter device, an amplifier device, a plug device and the like. The apparatus includes a sound measurement device having a probe microphone and a reference microphone isolated from each other and connected to a data processing unit having a control box and a speaker, both connected to a computer unit. Both microphones are adapted for measuring sound pressure levels inside said ear canal and outside in close proximity of said in-ear device respectively, the sound pressure levels corresponding to a known noise signal created by the speaker. The data processing unit being adapted for recording and processing the sound pressure levels read by both microphones corresponding to said known noise signal to provide a corresponding calculated value of a sound pressure level difference provided by the in-ear device. Used in conjunction with an expandable in-ear device, the apparatus monitors the acoustic seal in real time during the occlusion process of the in-ear device and determines when to stop the process. The present invention also refers to a corresponding method for determining in situ the acoustic seal provided by an in-ear device.
Patent JP-4137700-B2 (JP)
IPC: B65D83/14
Filed: 2003-05-23
Granted: 2008-08-20
Abstract: Valve for an aerosol container for dispensing a suspension of a substance in a liquid propellant contained therein. The valve comprises a valve body (1) having at least one orifice (16) to allow a quantity of the suspension to pass from the container into the valve. The valve further comprises a ring (18) disposed around the valve body (1), the ring being positioned below the at least one orifice to reduce the volume of suspension that can be accommodated within the container below the at least one orifice when the container is orientated with the valve at the bottom, the ring having at least one portion of reduced axial thickness to provide a trough (19) around the valve body below the at least one orifice. <IMAGE>
Patent JP-4105592-B2 (JP)
IPC: A61K31/44
Filed: 2003-05-26
Granted: 2008-06-25
Abstract: The present invention relates to novel huperzine A derivatives of formula (II), wherein Y is <CHEM>  or R'' and Y together form =CH; R is (C1-C5) alkyl, <CHEM> wherein n is 0 or 1, X is H, (C1-C5) alkyl; (C1-C5) alkyloxy; nitro, halogen, carboxy, alkyloxycarbonyl, hydroxymethyl, hydroxy, amino substituted by bis-(C1-C5) alkyl; -(CH2)mCOOZ, wherein m=0-5, Z is H or (C1-C5) alkyl; -CH=CH-G, wherein G is phenyl, furanyl, carboxy, alkyloxycarbonyl; and dihydro- or tetrahydro-pyridyl substituted by (C1-C5) alkyl at the nitrogen atom; R' is H, (C1-C5) alkyl, pyridoyl, benzoyl substituted by (C1-C5) alkyloxy; R'' is H or (C1-C5) alkyl; processes for their use as acetylcholinesterase inhibitor. <CHEM>
Patent JP-4274419-B2 (JP)
IPC: G10L21/0232
Filed: 2003-12-09
Granted: 2009-06-10
Abstract: An acoustic signal removal device includes: a stationary sound detection unit (18) for detecting a stationary sound in a mixed acoustic signal containing mixture of a known acoustic signal to be removed and another acoustic signal; an acoustic amplitude extraction unit (200) for extracting an acoustic amplitude spectrum from an acoustic signal; and a removal processing unit (104) for selecting a mixed acoustic amplitude spectrum of the frequency not matched with the frequency of the stationary sound among the extracted mixed acoustic amplitude spectra and removing a known acoustic amplitude spectrum from the mixed acoustic amplitude spectrum of the selected frequency. The acoustic signal removal device can exclude a stationary sound causing erroneous estimation when performing removal in the mixed acoustics, automatically and accurately predict change of the acoustics to be removed, and appropriately remove the acoustics.
Patent JP-4294468-B2 (JP)
IPC: B29C48/335
Filed: 2002-05-30
Granted: 2009-07-15
Abstract: The present invention relates to a process for printing active materials, such as adhesives, onto articles (500), such as absorbent articles or release paper, using a coater (100) with a multitude of applicators, which coats a surface (roll) (200) with a multitude of beads (220) of the active material; the process also uses a specific coating blade (300), which contact the surface with the active material with a certain angel and coats thereby the surface even better; preferred is also a specific second surface (roll) (400) arrangement. The invention also relates to articles obtainable by such a process and equipment specifically designed for the process. <IMAGE>
Patent JP-4083117-B2 (JP)
IPC: G06F11/22
Filed: 2002-06-27
Granted: 2008-04-30
Abstract: A Parallel Test Architecture (PTA) is provided that facilitates concurrent test, debug or programmable configuration of multiple electronic circuits (i.e., simultaneously). The PTA includes a communications path, a primary test controller, and a number of local test controllers. The primary controller provides stimulus, expected, and mask data to the local controllers over the communications path. The local controllers apply the stimulus data to the electronic circuits, receive resultant data generated by the circuits in response to the stimulus data, and locally verify the resultant data against the expected data substantially concurrently. When the communications path is implemented as an IEEE 1149.1 (JTAG) test bus, the primary controller can provide the expected and mask data to the local controllers over the TDO and TRSTN lines while the TAP controllers of the electronic circuits are in the Shift-IR or Shift-DR state to enable concurrent testing over a traditional five wire multi-drop IEEE 1149.1 test bus.
Patent JP-4278513-B2 (JP)
IPC: G06F9/445
Filed: 2002-07-23
Granted: 2009-06-17
Abstract: A system and method are provided for updating persistent data in a wireless communications device. The method comprises: executing system software; launching a run-time engine; receiving the patch manager run-time instructions with dynamic instruction sets and new code sections, including updated persistent data, in a file system section in nonvolatile memory; processing dynamic instruction sets; in response to processing the dynamic instruction sets, selectively updating persistent data in the system software selected from the group including radio frequency (RF) calibration data, nonvolatile system and user configuration data, resource data, nonvolatile system and user application data, and arbitrary data; and, executing the system software with the updated persistent data.
Patent JP-4370165-B2 (JP)
IPC: F16F7/00
Filed: 2002-07-19
Granted: 2009-11-25
Abstract: Apparatus for reducing sensitivity of an article to mechanical shock comprises a frame; first and second planar masses mounted in the frame for bi-directional movement relative to the frame along a first axis of displacement; a first lever pivotable about a first fulcrum secured to the frame; the lever having one end connected to the first mass and the other end connected to the second mass, and the fulcrum being disposed between the ends of the lever; whereby the torque exerted about the fulcrum by the first mass is countered by the torque exerted about the fulcrum by the second mass in response to a mechanical shock applied to the frame along the axis of displacement such that an article carried by the first mass in use has reduced sensitivity to the shock.
Patent JP-4346442-B2 (JP)
IPC: G01N21/64
Filed: 2002-11-19
Granted: 2009-10-21
Abstract: In a method for correcting for the size and/or shape of a measuring volume ( 18 )in a chemical and/or biological sample ( 14 ), especially in fluorescence spectroscopy, a measuring volume ( 18 ) located within the sample ( 14 ) is imaged to a detector means ( 44 ), using observing optics ( 32 ). The imaging is effected through a sample carrier w all ( 16 ) of a sample carrier ( 12 ) containing the sample ( 14 ). In the next step, the thickness of the sample carrier wall ( 16 ) is automatically determined. Thereafter, at least one lens ( 28 ) is shifted automatically along an optical axis of the observing optics ( 32 ) to correct for the size and/or shape of the measuring volume ( 18 ) as a function of the thickness of the sample carrier wall ( 16 ).
Patent JP-4268050-B2 (JP)
IPC: A61M25/02
Filed: 2002-11-27
Granted: 2009-05-27
Abstract: A gastrostomy device includes a tubular portion and an internal bolster having a radial wing secured to the tubular portion. The internal bolster is flexible and permits elastic deformation between a first orientation with the wing wrapped into a generally cylindrical configuration and a second orientation with the wing unfurled. A constraining member encases the internal bolster to retain the internal bolster in the first orientation and to cover at least a major portion of the wrapped wing. Removal of the casing permits the internal bolster to move from the first orientation to the second orientation. The internal bolster may be deployed by a ripcord, freeing the internal bolster into the patient' stomach and deploying the internal bolster to the second orientation. Alternatively, the internal bolster may be deployed by the constraining member being dissolved by the patient's bodily fluids located inside the patient's stomach.
Patent JP-4521481-B2 (JP)
IPC: A23L7/10
Filed: 2003-03-06
Granted: 2010-08-11
Abstract: A process for the production of short cooking time rice is characterized by that hulled rice of at least 10% moisture content, if required in packaging suitable for ready cooking, is heat treated for 1 to 30 minutes continuously or interrupted by equal or alternating capacity microwave radiation, to reach maximum 130° C. An apparatus for the production of short cooking time rice has a microwave furnace with a tunnel made from a suitable material, wherein the rice packed into packages is movable within the tunnel by a conveyor. Regarding the easy and short process, a remarkable energy saving is possible.
Patent JP-4637489-B2 (JP)
IPC: B60Q1/12
Filed: 2004-01-28
Granted: 2011-02-23
Abstract: The device has two intersecting headlights (14) to produce a light beam which is rotated towards left or right when a vehicle is in a situation of turn towards the left or right-hand side, respectively. A central unit (24) controls switching off failed headlights (14) and lights an auxiliary headlight (18) when the unit detects failure of the headlights (14) in directed position.
Patent JP-4579662-B2 (JP)
IPC: D21D5/16
Filed: 2004-12-09
Granted: 2010-11-10
Abstract: A method for manufacturing filtering baskets (1, 100) for filtering machines of fibres in aqueous suspension which comprises the step of preparing a plurality of mainly longitudinal developed shaped bars (3, 4, 20) and the step in which the shaped bars (3, 4, 20) are disposed side by side one close to another, at least some of the shaped bars (3, 4, 20) having the contact surfaces (5, 6, 7, 8, 24, 25) with the adjacent shaped bars (3, 4, 20) belonging to mutually convergent planes, to define a tubular structure (9) having a central longitudinal axis (X). The method further comprises the step of externally encircling the shaped bars (3, 4, 20) by means of two or more mutually coaxial according to the longitudinal axis (X) and mutually spaced annular elements (10).
Patent JP-3833681-B2 (JP)
IPC: C07K19/00
Filed: 2004-12-22
Granted: 2006-10-18
Abstract: The invention relates to an antigenic glycoprotein gp80 characterized by the following properties: it has a molecular weight (PM) close to 80 kDa; it is recognized by polyclonal antibodies directed against the glycoprotein gp300; it includes in association in the form a dimer to entities of the envelope transmembrane glycoprotein gp36, coded by the genome of a human retrovirus of the type HIV-2, susceptible of causing SLA or AIDS in human beings, or any glycoprotein having a molecular weight of the same order of magnitude, capable of forming an immunological complex of the type antigene-antibody, with antibodies directed against said gp80. The invention also relates to antibodies directed against said glycoprotein. It also relates to diagnostic and vaccination applications.
Patent JP-4160046-B2 (JP)
IPC: F16D11/00
Filed: 2003-06-17
Granted: 2008-10-01
Abstract: A treatment head of a tool machine and a member are relatively angularly positioned by an angularly indexable mount having a first coupling having first and second elements displaceable relative to each other, each formed with a respective array of a respective predetermined number of teeth, and respectively connected to the member and the treatment head. The number of teeth of the first-coupling first element varies by more than one from the number of teeth of the first-coupling second element. A second coupling meshable with the first coupling has first and second elements engageable with the first and second elements of the first coupling, fixed relative to each other, and each formed with a respective array of a respective predetermined number of teeth. The number of teeth of the second-coupling first element varies by more than one from the number of teeth of the second-coupling second element.
Patent JP-4502814-B2 (JP)
IPC: C12Q1/68
Filed: 2003-11-06
Granted: 2010-07-14
Abstract: The present invention relates generally to a diagnostic assay and, more particularly, an assay for measuring cell-mediated immune reactivity. Even more particularly, the present invention provides an assay and a kit for measuring a cell-mediated response to an antigen using whole blood or other suitable biological sample. The assay may be conducted using ligands to immune effector molecules or at the nucleic acid level, screening for expression of genes encoding the immune effector molecules. The assay is useful in therapeutic and diagnostic protocols for human, livestock and veterinary and wild life applications.
Patent JP-4603364-B2 (JP)
IPC: A61P25/04
Filed: 2003-11-25
Granted: 2010-12-22
Abstract: Disclosed are dipeptides that facilitate the intercellular communication mediated by gap junctions. The invention has a wide spectrum of useful applications including use in the treatment of diseases associated with impaired gap junction intracellular communication (GJIC).
Patent JP-4620472-B2 (JP)
IPC: A61P31/22
Filed: 2003-08-25
Granted: 2011-01-26
Abstract: Novel biaromatic vitamin D analogues have the general formula (I): and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for cosmetic applications.
Patent JP-4381992-B2 (JP)
IPC: F02D41/38
Filed: 2005-01-14
Granted: 2009-12-09
Abstract: Diesel engine, especially a large diesel engine, comprises an electronic control system (1) and several cylinders. Each cylinder is assigned to a module (10, 10', 10'', 10''') of the control system. Each of these control modules has an identically designed logic circuit with a first and a second functional part region (11, 12). The cylinder is controlled by the first functional part region. The global functions are influenced by a control device spread over the modules so that for at least one part of the module with the second functional part region interacting with second functional part regions of the other modules the global engine control is carried out in a redundant manner. In the event of an error, because of the redundancy at least one part of the engine output is maintained.
Patent JP-4744891-B2 (JP)
IPC: G01S5/02
Filed: 2005-02-10
Granted: 2011-08-10
Abstract: A system is disclosed that enables the estimation of the location of a wireless terminal in a wireless network. The illustrative embodiment works without requiring modifications to be made to the wireless terminal. Furthermore, the hardware of some embodiments of the present invention can be inexpensively deployed indoors. Some embodiments of the present invention are, therefore, ideally suited for use with legacy indoor systems. The system of the illustrative embodiment of the present invention, in some embodiments, uses an offline process and an online process for location estimation. The described system, however, can be used with other techniques for location estimation.