Patent CA-3015512-A1 (CA)
Inventor: RUSS HERMANN KURT
IPC: A61K31/451
Filed: 2017-02-24
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY  (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date                   WO 2017/147366 Al 31 August 2017 (31.08.2017)      WIPO I PCT (51) International Patent Classification:    (81) Designated States (unless otherwise indicated, for every A61K 31/451 (2006.01)    A61K 31/4704 (2006.01)    kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date:    HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, 24 February 2017 (24.02.2017)    KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language:                      English    NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (26) Publication Language:                 English    RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data:                             ZA, ZM, ZW. 62/299,290      24 February 2016 (24.02.2016)    US (84) Designated States (unless otherwise indicated, for every (71) Applicant (for all designated States except BB): TEVA    kind of regional protection available): ARIPO (BW, GH, PHARMACEUTICALS INTERNATIONAL GMBH    GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, [CH/CH]; Schlusselstrasse 12, 8645 Jona (CH).    TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (71) Applicant                             BB only): TEVA PHARMACEUTICALS DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, USA, INC. [US/US]; 1090 Horsham Road, North Wales, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, PA 19454 (US). SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: RUSS, Hermann, Kurt; Zurcherstrasse 37c,    GW, KM, ML, MR, NE, SN, TD, TG). 8852 Altendorf (CH). GEVA, Michal; Rozmarin 5, P.o. Published: Box 7253, Even-yehuda (IL). LAUFER, Ralph; Shenkin 55, 6523309 Tel Aviv (IL). ORBACH, Aric; Levona 1, ¨ with international search report (Art. 21(3)) 76350 Rehovot (IL). (74) Agent: GERSHIK, Gary, J.; Cooper & Dunham LLP, 30 Rockefeller Plaza, 20th Floor, New York, NY 10112 (US). = (54) Title: TREATMENT OF NEURODEGENERATIVE EYE DISEASE USING PRIDOPIDINE '                             = '''    ;:;.:== ... = ...... ===   .........      '     .......        ......                                      =r    r= .                                         = .. . left/Normat Eye            '""     :  ..................... -=       .... .....................................................  ......      = ....... ..................... ,..=    .......          . .. ,.;    õõ    .....      k,4                                                         , Right/Disease El = -==¨   cr)                                                 , .................................. ...       fig. I 1-1    (57) Abstract: The subject invention provides a method of treating a subject afflicted with a neurodegenerative eye disease compris -ing administering to the subject an amount of pridopidine effective to treat the subject.