baber/WOPTO huggingface dataset:
Patent SG-10201804883S-A (SG)
Title: Systems and methods for detection of cells using engineered transduction particles
Inventor: REY DIEGO ARIEL
Filed: 2014-03-11
Abstract: SYSTEMS AND METHODS FOR DETECTION OF CELLS USING ENGINEERED TRANSDUCTION PARTICLES Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity. Fig. 138
Patent SG-10201806680X-A (SG)
Title: Hair dye composition
Inventor: SAIMIYA HIROMI
Filed: 2015-06-05
Abstract: A hair dye composition comprising the following components (A), (B) and (C) and having pH (25 ° C) of 7.5 or more and 12 or less: (A): one or more azo dyes selected from the group consisting of the following (A-1), (A-2) and (A-3): OH Cl N N S N N SCH 3 OH Cl N N S N SO 2NH 2 OH Cl N N N N C H3 (A-1) (A-2) (A-3) (B): a cationic compound (C): 0.1 mass% or more and 8 mass% or less of at least one alkali metal salt of an acid selected from the group consisting of hydrochloric acid, carbonic acid and sulfuric acid. No Figure
Patent SG-10201807414R-A (SG)
Title: Method of inspecting flow rate measuring system
Inventor: JUN HIROSE
Filed: 2018-08-29
Abstract: METHOD OF INSPECTING FLOW RATE MEASURING SYSTEM Disclosed is a method of inspecting a flow rate measuring system used in a substrate processing system. The flow rate measuring system provides a gas flow path used for calculating a flow rate in a build-up method. A gas output by a flow rate controller of a gas supply unit of the substrate processing system may be supplied to the gas flow path. In the method, apart from a previously obtained initial value of a volume of the gas flow path, a volume of the gas flow path is obtained at the time of inspection of the flow rate measuring system. Then, the obtained volume is compared to the initial value. Figure 1
Patent SG-11201807322Y-A (SG)
Title: Service reservation method and device
Inventor: SHI LISHA
IPC: G06Q50/10
Filed: 2017-02-21
Abstract: SERVICE RESERVATION METHOD AND APPARATUS A service reservation method and apparatus are provided. The method includes: 5 receiving a reservation request for a preset service initiated by a preset instant messaging application (102); determining a service mode designated by the reservation request (104); and responding to the reservation request according to the service mode to enable an initiator of the reservation request to obtain the preset service (106). The technical solution according to the present application helps a user achieve a convenient and fast service reservation 10 operation. Figure 1 15
Patent SG-11201807575W-A (SG)
Title: Attendance processing method and apparatus
Inventor: YU LIYING
IPC: G06Q10/10
Filed: 2017-02-23
Abstract: ATTENDANCE PROCESSING METHOD AND APPARATUS An attendance processing method and apparatus are disclosed. The method may 5 include: determining a preset attendance event corresponding to a group to which a user belongs (102); acquiring attendance-related information corresponding to the user in the preset attendance event (104), and presenting the attendance-related information to the user (106). This method may arouse the attendance enthusiasm of users and help improve user experience. 10 Figure 1
Patent SG-11201810562T-A (SG)
Title: Information transmission method and device
Inventor: TANG HAI
IPC: H04W48/08
Filed: 2016-07-11
Abstract: Provided in the embodiment of the present application is an information transmission method and 5 device. The method comprises: a network equipment sends scheduling information of system information; and the network equipment sends the system information according to the scheduling information. The method and the device can save signaling overheads and increase the utilization rate of resources. 10 FIG. 1
Patent SG-11201908091Q-A (SG)
Title: Aqueous anti-pd-l1 antibody formulation
Inventor: RINALDI GIANLUCA
IPC: A61K39/395
Filed: 2018-03-06
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 13 September 2018 (13.09.2018) WIP0 I PCT mu °million °noI0 OilIIIIIDIDHoIllIIII111110 OIIIIII Oil (10) International Publication Number WO 2018/162446 Al (51) International Patent Classification: A61K 39/395 (2006.01) C07K 16/28 (2006.01) (21) International Application Number: PCT/EP2018/055404 (22) International Filing Date: 06 March 2018 (06.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 17159354.4 06 March 2017 (06.03.2017) EP (71) Applicant: MERCK PATENT GMBH [DE/DE]; Frank- furter Strasse 250, 64293 Darmstadt (DE). (72) Inventors: RINALDI, Gianluca; Via Gino Silvestrini 9, 00015 MONTEROTONDO (IT). FRATARCANGELI, Silvia; C.so Risorgimento 3, 03024 CEPRANO FR (IT). SHOPIK, Michael James; Via Publio Valerio 10, 00175 ROMA (IT). DEL RIO, Alessandra; Via Ildebrando Vi- vanti 108, 00144 ROMA (IT). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) 1-1 (54) Title: AQUEOUS ANTI-PD-L1 ANTIBODY FORMULATION (57) : The present invention relates to a novel anti-PD-L1 antibody formulation. In particular, the invention relates to an 0 aqueous pharmaceutical formulation of the anti-PD-L antibody Avelumab.
Patent SG-11201909195S-A (SG)
Title: A diving mask having a body provided with an exhaled air exhaust device including a check valve
Inventor: SORIGUE QUENTIN
IPC: B63C11/16
Filed: 2018-03-30
Abstract: A DIVING MASK HAVING A BODY PROVIDED WITH AN EXHALED AIR EXHAUST DEVICE INCLUDING A CHECK VALVE 5 The invention relates to a diving mask (10) comprising: a body (12) having a faceplate (20) and a flexible skirt (22), a snorkel (18) extending a top portion (14) 10 of the body (12); the body (12) includes an exhaled air exhaust device (100) that puts the bottom chamber (52) in fluid-flow connection with the air duct (90) of the snorkel (18). The invention is characterized by the fact that the 15 exhaled air exhaust (100) includes at least a first check valve (140) arranged to allow exhaled air from the bottom chamber (52) to flow towards the air duct (90) of the snorkel (18) during a stage in which the user is breathing out, the first check valve (140) being closed 20 during a stage in which the user is breathing in. Figure 2
Patent SG-11202000263Q-A (SG)
Title: Immunomodulatory retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy
Inventor: CHANDRARATNA ROSHANTHA A
IPC: A61K31/47
Filed: 2018-07-12
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau Iiiimmomiolollmomioloommolomoimiolomovoimill (43) International Publication Date 17 January 2019 (17.01.2019) (10) International Publication Number WO 2019/014492 Al WIPO I PCT (51) International Patent Classification: A61K 31/47 (2006.01) C07C 13/48 (2006.01) A61K 31/4709 (2006.01) (21) International Application Number: PCT/US2018/041892 (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) Priority Data: 12 July 2018 (12.07.2018) English English 62/532,233 13 July 2017 (13.07.2017) US 62/552,814 31 August 2017 (31.08.2017) US (71) Applicant: I0 THERAPEUTICS, INC. [US/US]; 1805 East Garry Avenue, Santa Ana, California 92705 (US). (72) Inventors: CHANDRARATNA, Roshantha A.; 26242 Via Corrizo, San Juan Capistrano, California 92675 (US). SANDERS, Martin E.; c/o Io Therapeutics, INC., 1920 4th Avenue, #2704, Seattle, Washington 98101 (US). CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (74) Agent: CULLMAN, Louis C. et al.; K&L Gates LLP, 1 Park Plaza, Twelfth Floor, Irvine, California 92614 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, — (54) Title: IMMUNOMODULATORY RETINOID AND REXINOID COMPOUNDS IN COMBINATION WITH IMMUNE MOD- ULATORS FOR CANCER IMMUNOTHERAPY RAft:x RARP RARy 0 1 8' 1 0' 1Cr io 4 3 Concentration (ntii FIG. 1 (57) : Disclosed herein are methods for treating cancer comprising administering CAR-modified immune cells and at least ,41 , ) one Retinoic Acid Receptor and/or Retinoid X Receptor active agent.
Patent HU-209050-B (HU)
Title: Method for preparing fodder for monogastric animals
Inventor: GEREBY JOZSEF
IPC: A23K1/24
Filed: 1986-01-07
Abstract: Folder giving acid reactions is made palatable and digestable to monogastric animals by the addn. to the fodder of 0.5-3% calcium-carbonate, 0.1-1% calcium-hydrogen-phosphate and 2-8 pref. 3-5% of a -cellulose fibre carrying cpd.. - These additions neutralise the acidity of the fodders and render it suitable for mono-gastric animals esp. pigs and hens.
Patent IS-1816-B (IS)
Inventor: WARRELLOW GRAHAM JOHN
IPC: C07D213/38
Filed: 1993-12-22
Abstract: Compounds of general formula (1) are described wherein Y is a halogen atom or a group -OR<1>, where R<1> is an optionally substituted alkyl group; X is -O-, -S- or -N(R<8>)-, where R<8> is a hydrogen atom or an alkyl group; R<2> is an optionally substituted alkyl, alkenyl, cycloalkyl or cycloalkenyl group; R<3> is a hydrogen or halogen atom or an -OR<9> group, where R<9> is a hydrogen atom or an optionally substituted alkyl, alkenyl, alkoxyalkyl, or alkanoyl group, or a formyl, carboxamido or thiocarboxamido group; R<4> and R<5>, which may be the same or different, is each a group (CH2)nAr, where Ar is a monocyclic or bicyclic aryl group optionally containing one ore more heteroatoms selected from oxygen, sulphur or nitrogen atoms and n is zero or an integer 1, 2 or 3; R<6> is a hydrogen atom or an optionally substituted alkyl group; R<7> is a hydrogen atom or an optionally substituted alkyl group; and the salts, solvates, hydrates and N-oxides thereof. Compounds according to the invention are potent, selective and orally active PDE IV inhibitors and are useful in the prophylaxis and treatment of asthma and other diseases. <IMAGE>
Patent ZA-9636-B (ZA)
Title: Method of and apparatus for adjusting the moisture content of a fuel component for a smoking article
Inventor: MEIRING ROBERT LEONARD
IPC: A24D1/22
Filed: 1996-01-03
Abstract: A method of and apparatus for adjusting and controlling the moisture content of carbonaceous fuel components used in making smoking articles comprises a mass flow accumulator and a dryer through which the fuel components are conveyed. Unheated air is flowed over the fuel components in the accumulator to adjust and maintain the moisture content of the fuel components to a level which permits cutting of the fuel components without chipping or cracking. After the fuel components are cut into individual fuel elements and combined with an aerosol generator or substrate they are conveyed through the dryer where heated air is flowed over them to further reduce the moisture content to a desired level for further processing and manufacture into smoking articles. <IMAGE>
Patent HU-183793-B (HU)
Inventor: FARKAS ISTVAN
IPC: H04S1/00
Filed: 1982-01-27
Abstract: Die Erfindung betrifft eine Schaltungsanordnung zur Dekodierung von Stereo-Signalen in einem Polarmodulationssystem, die durch Ergänzung mit zusätzlichen Bauteilen auch zur Dekodierung in einem Pilottonsystem anwendbar ist. Sie enthält einen Amplitudenvergleicher 16, ein Phasenvergleicher 17, einen Stereo-Demodulator 11, einen spannungsgesteuerten Oszillator 13, Eingangs- und Ausgangspufferschaltungen 9, 12 sowie Verstärker, wobei die ersten Eingänge des Amplitudenvergleichers und des Phasenvergleichers miteinander verbunden sind, deren zweite Eingänge ebenso wie der zweite Eingang des Stereo-Demodulators mit dem Ausgang des spannungsgesteuerten Oszillators in Verbindung stehen. Erfindungsgemäß ist zwischen den Eingängen des Amplitudenvergleichers und des Phasenvergleichers und dem Ausgang des spannungsgesteuerten Oszillators jeweils ein Frequenzteiler 15; 15´vorgesehen, deren Eingänge miteinander verbunden sind. Der Ausgang des ersten Frequenzteilers ist mit dem zweiten Eingang des zweiten Frequenzteilers, dem zweiten Eingang des Phasenvergleichers und dem zweiten Eingang des Stereo-Demodulators verbunden, während der Ausgang des zweiten Frequenzteilers am zweiten Eingang des Amplitudenvergleichers liegt. Fig.3
Patent HU-209133-B (HU)
Title: Method for producing artificial resin based binding materials for protecting buildings
Inventor: LABENBACHER ADOLF
IPC: C08F2/06
Filed: 1986-02-19
Abstract: Process for the preparation of binders of the synthetic resin type which are soluble in aliphatic hydrocarbon solvents for the protection of buildings, based on copolymers of vinylaromatic products and of (meth)acrylic esters. The process is characterised in that the following are polymerised in solution or in bulk as far as a limiting viscosity number of 30 to 70 ml/g (measured in chloroform): a. 40 to 70% by weight of styrene and/or of p-methylstyrene b. 30 to 60% by weight of esters of (meth)acrylic acid with alkanols containing 4 to 10 C atoms whose homopolymers exhibit a glass transition temperature Tg lower than 25 DEG C, c. 0 to 20% by weight of diesters of maleic and/or fumaric acid with alkanols containing 4 to 10 C atoms, whose homopolymers exhibit a glass transition temperature Tg lower than 25 DEG C, and d. 0 to 5% by weight of esters of (meth)acrylic acid with aminoalcohols containing 4 to 10 C atoms, the sum of the percentages having to be 100. The binders prepared according to the invention can be used without the plasticising adjuvants usually needed in the case of copolymer binders intended for paints for facades.
Patent HU-194176-B (HU)
Title: Process for production of derivatives of new 7-phormildekahydridinoline
Inventor: SCHAUS JOHN M
IPC: A61K31/47
Filed: 1983-07-27
Abstract: A 1-substituted-3-permissibly-substituted-6-oxodecahydroquinoline is converted to the corresponding 7-formyl derivative and then, upon treatment with hydrazine, may be cyclized to a tautomeric mixture of 5-substituted-7-permissibly-substituted-4, 4a, 5, 6, 7, 8, 8a, 9-octahydro-1H (and 2H)-pyrazolo [3,4-g] quinolines.
Patent HU-205995-B (HU)
Inventor: SOMLAI GYULA
IPC: G01P15/00
Filed: 1990-02-20
Abstract: A találmány tárgya detektor, szállítmányokat ért ejtőhatás jelzésére, amelynek a szállítmányhoz rögzített házában (1) egyik végén fixen rögzített tartószen' van a vízszintes tengely irányában rögzítve; a tartószerv szabad végéhez súly (4) van erősítve. A találmány szerinti detektor újdonsága abban van, hogy a befogott tartószervet kis rugalmasságú, maradó alakváltozásra képes befogott tartó (3), pl. alumíniumszalag képezi. A súly (4) környezetében különböző nagyságú inercianyomaték értékekre kalibrált skála (5) van elhelyezve. A detektorhoz önmagában ismert dőlésjelző detektorok vannak társítva. A szállítónyon több detektor van elhelyezve, és ezen detektorok tengelyei egymáshoz képest 90°-kal térnek el. "fc.'  S- if CQ 1. ábra HU 205 995 A leírás terjedelme: 4 oldal (ezen belül 1 lap ábra)
Patent HU-184424-B (HU)
Inventor: AURICH HORST
IPC: D05B21/00
Filed: 1981-04-10
Abstract: Das erfindungsgemaesse Verfahren und die Vorrichtung dienen vorzugsweise zum automatischen Naehen von Bekleidungsteilen. Das Ziel besteht in der Einfachheit der Konstruktion u. den kurzen Umruestzeiten. Aufgabe: Mit einem Minimum an technischen Mitteln eine grosse Palette von Teilen mit unterschiedlicher Konfiguration zu naehen, insbesondere soll auf zusaetzliche Fuehrungselemente beim geradlinigen Nahtverlauf verzichtet werden. Erfindung: Fuer den kurvenfoermigen Nahtverlauf werden eine Einstechnadel als Zentrierung, Mittel zum definierten Anheben des Drueckerfusses sowie eine Blasduese mit Luftaustrittsoeffnung in Drehrichtung eingesetzt. Die erfindungsgemaessen technischen Mittel werden durch das gleiche Signal aktiviert sowie in Ruhestellung gebracht.
Patent LT-4647-B (LT)
Title: Method for producing pourable methionine salt based animal food supplement and the granulate thus obtained
Inventor: BINDER WOLFRAM
IPC: A23K20/142
Filed: 1999-08-31
Abstract: The invention relates to a method for producing a pourable, methionine salt based animal food supplement which is easy to handle, wherein a granulated product is manufactured from a methionine salt solution which can be obtained according to traditional methods. The invention further relates to methioninate granulated products that are thus obtained.
Patent RS-50005-B (RS)
Inventor: MATTSON ANDERS
IPC: A61K31/4439
Filed: 1998-05-25
Abstract: So magnezijum-S-omeprazoltrihidrat.Prijava Prijava ima 9 patentnih zahteva.
Patent ZA-87468-B (ZA)
Title: Tetrahydrocarbazole 1-alkanoic acids
Inventor: GUINDON YVAN
IPC: A61K31/403
Filed: 1987-01-22
Abstract: Tetrahydrocarbazole 1-alkanoic acids are disclosed. The compounds act as prostaglandin and thromboxane antagonists and are useful in treating asthma, diarrhea, hypertension, angina, platelet aggregation. cerebral spasm, premature labor, spontaneous abortion and dysmenorrhea and as cytoprotective agents.
Patent ZA-93769-B (ZA)
Title: Herbicides,
Inventor: CAIN PAUL ALFRED
IPC: C07D261/18
Filed: 1993-02-04
Abstract: 4-Benzoyl isoxazole derivatives of general formula (I): <CHEM>     wherein     R represents a hydrogen atom or a group -CO2R<5>; R<1> represents methyl, isopropyl, cyclopropyl or 1-methylcyclopropyl;     R<2> represents -S(O)nR<5><1>; R<3> represents a chlorine, bromine or fluorine atom, a straight- or branched- chain alkyl, alkoxy, haloalkyl or haloalkoxy group, an alkenyl group or a methyl or ethyl ester group; R<4> represents a chlorine, bromine or fluorine atom; an alkyl, alkoxy haloalkyl, haloalkoxy, -S(O)pR<5><3> or cyano group;     R<5> represents an alkyl or haloalkyl group;     R<5><1> and R<5><3> independently represent an alkyl group, and     n and p independently represent zero, one or two, and their use as herbicides is described.
Patent AT-394493-B (AT)
IPC: A61K33/30
Filed: 1989-05-11
Granted: 1992-04-10
Abstract: The preparation contains as active ingredients a mixture of
 a) L- alpha -aminosuccinic acid (L-aspartic acid> b) L- beta -mercaptoalanine (L-cysteine> c) L- alpha -aminoglutaric acid (L-glutamic acid> d) sodium selenate (Na2SeO4) and
 e) zinc acetate (Zn(CH3OO)2) or zinc sulphate (ZnSO4).
Patent CH-642228-B (CH)
Inventor: OSKAR LEUTHOLD
IPC: H02M3/335
Filed: 1980-10-16
Abstract: A converter (300) for converting an a.c. voltage (SP) into a direct current (i3), characterized in that it comprises a first elementary converter (21) which, in response to the a.c. voltage (SP), provides a pulsed direct current (i1), the mean value (i1) of which is a steeply rising function of the amplitude A of the a.c. voltage (SP), and a second elementary converter (22) which, in response to the current i1 provides a current i3, the value of which is a steeply falling function of i1. Used for regulating the amplitude of the oscillation signal of an oscillator.
Patent CH-615312-B (CH)
Inventor: NISHIMURA IZUHIKO
IPC: G04F10/04
Filed: 1975-07-07
Abstract: An electronic timepiece including a variable divider for producing timekeeping signals for the smallest digit of time displayed having a frequency which is not evenly divisible into the frequency produced by the time standard. An oscillator includes a time standard for producing a high frequency time standard signal having a frequency of KNHz where K and N are positive integers other than O, and a divider adapted to evenly divide the high frequency time standard signal by KM, where M is an integer other than O, and in response thereto produce a KN<->M frequency signal having a frequency not evenly divisible by IP, where I is a positive integer other than K and P is an integer. A counter is provided for producing output signals representative of a counting cycle in response to an input pulse signal applied thereto, and a display device is coupled to the counter for displaying each count of the cycle thereof. A detecting circuit is coupled to the counter to detect at least one predetermined count of each counting cycle thereof, and in response to each predetermined count produces a detection pulse. The variable divider is coupled to the detection circuit and has a first and second division ratio. The variable divider is adapted to receive the KN<->M frequency signal and in response thereto divides same by a first division ratio, and in response to each said detection pulse applied thereto divides the KN<->M frequency pulse by said second division ratio to thereby produce an input pulse signal to the counter having a frequency evenly divisible by IP.