baber/WOPTO huggingface dataset:
Patent CA-3073117-A1 (CA)
Inventor: CHANG GREGORY P
IPC: A61K47/68
Filed: 2018-08-16
Abstract: Multi-specific binding proteins that bind NKG2D receptor, CD16, and a tumor- associated antigen selected from EGFR, HLA-E, CCR4, and PD-L1 are described, as well pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.
Patent CA-3074320-A1 (CA)
Inventor: LI ZHEN
IPC: A61K47/54
Filed: 2018-09-13
Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, able to inhibit Angiopoietin-like 3 (also called ANGPTL3, ANGPL3, angiopoietin-like protein 3) gene expression, and compositions that include ANGPTL3 RNAi agents. Also disclosed are methods of use of ANGPTL3 RNAi agents and compositions. The ANGPTL3 RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery to cells, including to hepatocytes. Pharmaceutical compositions that include one or more ANGPTL3 RNAi agents, optionally with one or more additional therapeutics, are described. Deliver}' of the ANGPTL3 RNAi agents in vivo provides for inhibition of ANGPTL3 gene expression, and can result in lower triglycerides and. or cholesterol levels in the subject.  The RNAi agents can be used in methods of treatment of ANGPTL3 -related diseases and disorders, including cardiometabolic diseases such as hyper-triglyceridemia and hyperlipidemia.
Patent CA-3079928-A1 (CA)
Inventor: PENG CHENG-CHUN
IPC: G02B1/04
Filed: 2018-10-22
Abstract: Contact lenses that have an ion-impermeable portion and an ion-permeable portion that are able to move on the eye without binding to the eye are described. The contact lenses exhibit an average ionoflux transmittance of at least 1.34x10-4 mm/min. One or more electronic components can be included in the contact lenses. Methods of making the contact lenses are also described.
Patent CA-3082162-A1 (CA)
Inventor: LISZKAI TAMAS
IPC: G21C15/02
Filed: 2018-12-19
Abstract: In some embodiments, a nuclear reactor vessel comprises a containment vessel for a reactor pressure vessel (RPV); a control rod drive mechanism (CRDM) located in the containment vessel, the CRDM  including drive motors configured to move control rods into and out of a nuclear reactor core located in the RPV; and a partition extending across a portion of the containment vessel configured to retain the drive motors in a separate fluid-tight barrier region within the containment vessel. Other embodiments may be disclosed and/or claimed.
Patent CA-3082237-A1 (CA)
Title: Systems and methods for enhanced mapping and classification of data
Inventor: OLIVER DAVID
IPC: G06Q40/00
Filed: 2018-11-06
Abstract: The present disclosure relates to systems and methods for enhanced mapping of transaction data to a target document, and for classifying line items of the mapped transaction data, using classification algorithms. Embodiments provide a system including a column mapping module to receive a target scheme specifying a target structure for the target document, receive transaction data having a source structure, and map at least one source column to at least one target column of the target columns based on application of classification algorithms to features identified from the source transaction data. The system also includes a row classification module to classify the rows of the mapped transaction data into classification categories. The system also includes a validation handler to receive validation input from a user, validating the column mapping and/or the row classification. The validating including accepting the recommendation or rejecting the recommendation and selecting a correct choice.
Patent CA-3083961-A1 (CA)
Inventor: DAI HUIBIN
IPC: E04F15/10
Filed: 2018-01-26
Abstract: L'invention concerne un procédé de traitement de revêtements de sol en plastique utilisant l'impression numérique. La présente invention vise à résoudre le problème des coûts élevés encourus lors de la fabrication d'un revêtement de sol classique. La caractéristique principale d'une solution technique selon la présente invention est le procédé de traitement des revêtements de sol en plastique utilisant l'impression numérique, comprenant les étapes suivantes : A. préparation d'un matériau de substrat ; B. mélange ; C. moulage par injection ; D. prise ; E. gaufrage, des blocs marqueurs sont sculptés sur les bords d'un rouleau de gaufrage, le rouleau de gaufrage et un rouleau de motif de base appuyant sur les surfaces d'un substrat en pierre-plastique pour produire des cycles de répétition d'un motif, et des marqueurs de motif appariés étant produits à équidistance ; F. refroidissement ; G. découpe, sélection d'un premier point et d'un second point et découpe au niveau du second point ; et H. impression numérique, l'impression démarrant lorsqu'un dispositif de détection d'une imprimante numérique détecte le premier point de chaque substrat en pierre-plastique, et l'impression s'interrompant lorsque le second point est détecté. Le procédé de traitement de revêtements de sol en plastique utilisant l'impression numérique de la présente invention permet, en imprimant le motif directement sur les surfaces du substrat en pierre-plastique avec l'imprimante numérique, d'éviter un processus de fixation d'un film couleur et d'une couche résistante à l'usure, ce qui réduit les coûts et augmente l'efficacité de travail.
Patent CA-3085248-A1 (CA)
Title: Hinged kiln brick protective collar
Inventor: NARDELLA ANTHONY
IPC: F27D1/18
Filed: 2020-07-02
Abstract: A hinged protective collar for a kiln with rigid first and second body portions, each with a shape and size corresponding to the shape and size of a portion of a peripheral edge surface of the kiln sidewall and a hinge structure that pivotally couples the first and second body portions so they can be pivoted from a collapsed configuration to an expanded, use configuration, For a kiln with a faceted shape, each of the first and second body portions has a given number of corresponding facets. The hinged protective collar can span a portion of the periphery of the kiln, or the hinged protective collar could span 360 degrees and could have first and second hinge structures coupling the first and second body portions. The first and second body portions can have upturned proximal and, additionally or alternatively, distal end portions to prevent damage to kiln brick.
Patent CA-3086249-A1 (CA)
Inventor: PARTUSCH GEORG
IPC: B32B5/02
Filed: 2018-12-11
Abstract: The invention relates to a method for producing polyurethane sandwich molded parts, containing at least one core layer and at least one reinforcing fiber layer, wherein (i) at least one reinforcing fiber layer is applied to a core layer and a moisture-curing polyurethane adhesive is applied to a reinforcing fiber layer, (ii) the part from (i) is placed into a mold and is pressed in the mold and the moisture-curing polyurethane adhesive is cured and (iii) the molded part from (ii) is removed from the mold and optionally finished, the moisture-curing polyurethane adhesive being applied before or after the application of the reinforcing fiber layer to the at least one core layer and the moisture-curing polyurethane adhesive being brought into contact with water or with a solution containing water in order to cure the the moisture-curing polyurethane adhesive. The invention further relates to a polyurethane sandwich molded part that can be obtained by a method of this type and to the use of a polyurethane sandwich molded part in vehicles.
Patent CA-3086579-A1 (CA)
Inventor: HERRIMAN ELIZABETH
IPC: B25H5/00
Filed: 2020-07-10
Abstract: A shelf system that may be used with a vehicle is described. The shelf system may have a shelf member that selectively pivots between a raised position and a lowered position. The shelf system may have a frame system as well as a sub-frame system to support it within the vehicle.
Patent CA-3086596-A1 (CA)
Title: Method for controlling the supply of fuel to a combustion chamber of a turbine engine, fuel supply system, and turbine engine
Inventor: BOUTALEB MOHAMMED-LAMINE
IPC: F02C7/228
Filed: 2018-12-21
Abstract: The invention relates to a method for controlling the fuel injection of a turbine engine using a fuel supply circuit (100). The supply circuit (100) comprises a pilot injection line (141) and a main injection line (142). During a transition of the supply distribution between the pilot injection line (141) and the main supply line (142), the method comprises the following steps: a) determining at least a minimum value to be maintained for a pressure value; b) determining at least one hydraulic quantity of the supply circuit; c) based on the determined hydraulic quantity of the supply circuit, calculating a calculated fuel supply distribution value corresponding to the minimum value to be maintained; and switching the fuel supply distribution to the calculated fuel distribution value.
Patent CA-3091985-A1 (CA)
Inventor: PURDY CLAY
IPC: E21B43/22
Filed: 2020-09-03
Abstract: Method of spearheading an acid into a wellbore adapted to avoid the gelation of a friction reducer polymer, wherein said method comprises: injecting a synthetic or modified acid composition down a wellbore, said composition comprising: a synthetic or modified acid; a solvent; and a chelating agent, optionally the composition may comprise a corrosion inhibitor package;  allowing sufficient time for the synthetic or modified acid composition to react with material which require acidic treatment; and injecting a fracturing composition comprising a liquid and a friction reducing polymer down the wellbore.
Patent CA-3093380-A1 (CA)
Title: Compositions for use in balancing microbiome
Inventor: GHANNOUM AFIF
IPC: A61K35/741
Filed: 2019-03-08
Abstract: The disclosure generally provides a method of balancing microbiome and/or improving nutrient absorption, treating gut inflammation, and/or balancing the level of Firmicutes and Bacteroidetes in the gut of a subject in need thereof, the method comprising consumption by, or administration to the subject of a composition comprising a nutrient in combination with a probiotic composition comprising (i) an isolated non-pathogenic fungal strain and (ii) an isolated non-pathogenic bacterial strain.
Patent CA-3093531-A1 (CA)
Title: Systemes et procedes de desinfection d'equipement de parc d'attractions
Inventor: MAJDALI DAVID
IPC: A63G7/00
Filed: 2018-11-15
Abstract: Un système de désinfection pour un parc d'attractions comprend une station de désinfection disposée le long d'un trajet de manège d'un manège du parc d'attractions. La station de désinfection comprend un boîtier conçu pour recevoir un véhicule de manège lorsque le véhicule de manège se déplace le long du trajet de manège, une source de lumière ultraviolette configurée pour transmettre une lumière ultraviolette vers une surface du véhicule de manège, et un système de commande conçu pour détecter une position du véhicule de manège le long du trajet de manège et pour activer la source de lumière ultraviolette lorsque le système de commande détermine que le véhicule de manège est positionné dans une première position particulière par rapport au boîtier.
Patent CA-3093809-A1 (CA)
Title: Combination therapy for ttr amyloidosis
Inventor: ROBERTS MICHAEL J
IPC: C12N15/113
Filed: 2019-03-12
Abstract: The present invention is directed to compositions and methods for the treatment of transthyretin-associated (TTR) amyloidosis and in particular, compositions and methods that employ an effective amount of tolcapone and an RNAi molecule in combination for the treatment of transthyretin-associated amyloidosis.
Patent CA-3095021-A1 (CA)
Inventor: NG CHOON-SUN JAMES
IPC: E21B44/00
Filed: 2018-08-17
Abstract: There are described methods, systems, and techniques for performing automated drilling of a wellbore.  The wellbore is drilled according to one or more drilling parameter targets associated with one or more corresponding drilling parameters. A formation type through which the drilling is proceeding is determined. The one or more drilling parameter targets according to the formation type through which the drilling is proceeding are categorized.
Patent CA-3095687-A1 (CA)
Inventor: ZHOU HUAXING
IPC: C10C1/20
Filed: 2019-03-25
Abstract: La présente invention concerne des procédés de préparation de matériaux à partir de charges lourdes polyaromatiques. En particulier, l'invention concerne un procédé chimique pour convertir des charges lourdes avec des molécules ou des espèces d'hydrocarbures polyaromatiques prédominantes, comprenant les résidus de raffinage ou d'extraction pétrochimique, sous forme de matériaux thermodurcis ou thermoplastiques qui peuvent être utilisés seuls ou en tant que composant dans un matériau composite.
Patent CA-3096202-A1 (CA)
Inventor: LIM WENDELL A
IPC: C07K16/28
Filed: 2019-04-04
Abstract: L'invention concerne des méthodes de traitement d'un sujet atteint d'un glioblastome exprimant l'EGFRvIII. Les méthodes selon la présente invention impliquent l'administration au sujet d'un circuit moléculaire qui est amorcé par l'EGFRvIII pour induire un ou plusieurs agents thérapeutiques codés spécifiques pour un ou plusieurs antigènes exprimés par le glioblastome. L'invention concerne également des acides nucléiques contenant des séquences codant pour tout ou partie de tels circuits, ainsi que des cellules, des cassettes d'expression et des vecteurs qui contiennent de tels acides nucléiques. L'invention concerne également des kits permettant de mettre en uvre les méthodes décrites.
Patent CA-3099769-A1 (CA)
Title: Reference signal transmission method and communications device
Inventor: LIU YONG
IPC: H04W72/04
Filed: 2019-04-28
Abstract: Disclosed are a method for transmitting a reference signal, and a communication device. The method comprises: a first communication device determining a first frequency band according to a first initial resource index, a second initial resource index, a first configuration bandwidth and a second configuration bandwidth, wherein the first initial resource index is larger than or equal to the second initial resource index, and the first initial resource index is smaller than or equal to the sum of the second initial resource index and the second configuration bandwidth; and the first communication device receiving, on the first frequency band, a reference signal. Through the implementation of the present application, the actual transmission bandwidth of a reference signal can be determined accurately.
Patent CA-3103053-A1 (CA)
Title: Vis destinee a etre vissee dans de la matiere plastique
Inventor: ACHENBACH MICHAEL
IPC: F16B25/00
Filed: 2019-06-21
Abstract: L'invention concerne une vis (10) pour couper un contre-filetage dans un article en matière plastique. La vis comprend une partie filetée inférieure (F) et une partie filetée supérieure (T). La partie filetée inférieure comprend un diamètre plus grand et sa pointe recouvre une surface plus grande en comparaison avec la partie filetée supérieure.
Patent CA-3104893-A1 (CA)
Title: Appareil et procede de traitement oculaire pourvus de sources de pression independantes
Inventor: BERDAHL JOHN
IPC: A61B3/10
Filed: 2019-06-27
Abstract: L'invention concerne un appareil pouvant comprendre un couvercle de gauche, dimensionné et façonné pour s'adapter sur un il gauche d'un patient pour définir une cavité de gauche entre le couvercle de gauche et une surface antérieure de l'il gauche et un couvercle de droite, dimensionné et façonné pour s'adapter sur un il droit du patient pour définir une cavité de droite entre le couvercle de droite et une surface antérieure de l'il droit. L'appareil peut comprendre une source de pression de gauche pour appliquer un fluide de travail de gauche à la cavité de gauche, la source de pression de gauche pouvant générer une pression de cavité de gauche comprenant une pression de jauge négative de gauche et une source de pression de droite pour appliquer un fluide de travail de droite à la cavité de droite, la source de pression de droite pouvant générer une pression de cavité de droite comprenant une pression de jauge négative de droite, la source de pression de droite pouvant être séparée de la source de pression de gauche. La source de pression de gauche peut être conçue pour générer une pression de cavité de gauche indépendamment de la source de pression de droite et la source de pression de droite peut être conçue pour générer une pression de cavité de droite indépendamment de la source de pression de gauche.
Patent CA-3106179-A1 (CA)
Inventor: DIAMANTI MAURIZIO
IPC: A47J31/44
Filed: 2019-07-11
Abstract: This invention relates to an apparatus (1) for making a beverage, comprising an infusion chamber (21) suitable for receiving a capsule containing a food substance for making a beverage, an insertion opening (31) for inserting the capsule into the apparatus (1), a transfer channel (32) for transferring the 5 capsule from the insertion opening (31) to the infusion chamber (21), an image acquisition device (4) which is intended, in use, to acquire at least one image of a portion of the capsule. The image acquisition device (4) includes an optical sensor (42) facing an image capture zone (40) in which, in use, said capsule is located or passes. The apparatus (1) further comprises a 0 viewing window (45), made of transparent material, which is interposed between the optical sensor (42) and the image capture zone (40). The viewing window (45) has a first face (451) facing the optical sensor (42) and a second face (452) facing the image capture zone (40). The apparatus (1) further comprises a heating element (6) applied to the viewing window (45) 5 or incorporated in the viewing window (45). The heating element (6) is an electrical resistor-type heater and is electrically connectable to an electricity supply. The heating element (6) is intended for heating the viewing window (45) during use of the apparatus (1).
Patent CA-3106331-A1 (CA)
Title: Microfluidic devices and methods of use
Inventor: KELLEY SHANA OLWYN
IPC: G01N1/34
Filed: 2019-07-15
Abstract: Microfluidic devices, kits systems and methods are provided for high through put phenotypic separation of magnetically labelled cell samples. The devices and methods can be used for example to sort cells based on level of target marker and to sort screen cells, such as CRISPR screen cells and other screens with a large number of target cells, to isolate target cells and putative genetic modifiers.
Patent CA-3107188-A1 (CA)
Inventor: GHANOUNI KAV
IPC: A24F40/20
Filed: 2019-07-31
Abstract: Described herein is a method of generating aerosol from an aerosol-generating substrate using an aerosol-generating device, the aerosol-generating device comprising at least three heating zones disposed so as to each heat a different section of the substrate to generate an aerosol without burning. The method comprises sequentially generating aerosol from each different section of substrate, wherein during heating; (i) a section of substrate is heated to an aerosol-generation temperature; (ii) another section of substrate which is heated to an intermediate temperature which is below the aerosol-generation temperature but and approximately equal to or above the minimum operating temperature; (iii) at least one of the remaining sections of substrate are heated to a minimum operating temperature which is at least sufficient to prevent condensation of volatilised components on or in the vicinity of those sections; and wherein once aerosol has been generated from a section, (a) the temperature in that section is reduced from the aerosol-generation temperature to the minimum operating temperature, (b) the section previously heated to the intermediate temperature is heated to the aerosol- generation temperature, and (c) a further section is heated to the intermediate temperature.
Patent CA-3107806-A1 (CA)
Title: Drop-in insert for a valve cage of a pump
Inventor: FORD MICHAEL BRENT
IPC: E21B34/06
Filed: 2021-02-01
Abstract: A drop-in insert for a valve cage is adapted for use with a subsurface pump.  The insert can be positioned in a valve cage housing. The insert includes a cradle, a base, a plurality of angled ribs, and an upper ring. In one embodiment, the insert may also include an extended nose region. Upper ring can abut an interior diameter of the housing, providing a smooth transition for pumped fluid, thereby decreasing turbulent fluid flow and promoting improved fluid flow during pumping operations. The insert can be dropped into position in the housing.  Alternatively, the insert can be positioned in the housing by an interference fit or the like. The housing and insert can be part of a valve cage assembly that includes a ball, seat, seat plug, and end cap. The assembly may include an 0-ring component which can cushion the insert, thereby prolonging the life of the insert.
Patent CA-3108736-A1 (CA)
Inventor: GLUSKIN MARK A
IPC: G06Q10/20
Filed: 2012-05-04
Abstract: ABRÉGÉ DE LA DIVULGATION : Il est décrit des systèmes, des procédés et un appareil qui permettent danalyser un système dinfrastructure, consistant à mesurer un paramètre associé au système dinfrastructure, à enregistrer électroniquement le paramètre mesuré pour constituer des données, à transférer les données vers une unité de linfrastructure qui peut être à distance du système dinfrastructure, à analyser les données pour générer un modèle du risque et à prédire une caractéristique du système dinfrastructure en fonction du risque. Un plan de mise en uvre peut être généré et/ou des services dentretien peuvent être effectués en fonction de la caractéristique prédite. Date reçue/Date Received 2021-02-09
Patent CA-3110353-A1 (CA)
Inventor: CRUSE GLENN P
IPC: C12N15/63
Filed: 2019-08-27
Abstract: Compositions and methods for modulating Kit biological activities are provided. In some embodiments, the presently disclosed subject matter provides antisense oligomers having 10 to 50 linked nucleotides, wherein the antisense oligomer is targeted to a region of a Kit-encoding pre-mRNA, and further wherein the targeted region includes sequences involved in splicing of the Kit-encoding pre-mRNA. Also provided are expression vectors encoding the antisense oligomers disclosed herein, morpholino oligomer derivatives of the presently disclosed antisense oligomers, pharmaceutical compositions that include the disclosed antisense oligomers, expression vectors, and/or morpholino oligomers, and methods for modulating splicing of a Kit pre-RNA in a cell and/or a tissue, inducing apoptosis in mast cells, and treating diseases, disorders, and/or conditions associated with Kit expression.
Patent CA-3110924-A1 (CA)
Inventor: GAGNON PIERRE
IPC: B64D11/06
Filed: 2014-04-29
Abstract: An exit row table includes a table surface deployable between a retracted position and a deployed position. An arm supports the table surface at a first end, through an arm pivot. A scissor jack is connected to the arm via a slide for deploying the arm and table surface between two positions. A support connected to the arm and to the slide disposed in an aircraft structure interior. A rail guides travel of the slide connected to the support through a support pivot allowing the support to pivot from a vertical orientation to a horizontal orientation. The support moves along the rail and the scissor jack is connectable at an end thereof to at least one of the rail, a frame disposed in the aircraft structure interior, or a portion of an interior of a sideledge of the aircraft.
Patent CA-3113521-A1 (CA)
Title: Video coding in which a block is split into multiple sub-blocks in a first direction, whereby interior sub-blocks are prohibited from splitting in the first direction
Inventor: ABE KIYOFUMI
IPC: H04N19/176
Filed: 2019-03-04
Abstract: An encoder that encodes a current block in a picture includes circuitry and memory. Using the memory, the circuitry: splits the current block into a first sub block, a second sub block, and a third sub block in a first direction, the second sub block being located between the first sub block and the third sub block; prohibits splitting the second sub block into two partitions in the first direction; and encodes the first sub block, the second sub block, and the third sub block.