baber/WOPTO huggingface dataset:
Patent CA-2653460-A1 (CA)
Title: Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its medical use
Inventor: TIMMERMANN DANIEL B
IPC: C07D471/08
Filed: 2007-05-29
Abstract: This invention relates to a novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its use in the manufacture of pharmaceutical compositions. The compound of the invention is found to be a cholinergic ligand at the nicotinic acetylcholine receptors. Due to its pharmacological profile the compound of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
Patent CA-2654010-A1 (CA)
Inventor: MELKI JOHN R
IPC: C12Q1/68
Filed: 2006-06-02
Abstract: The present invention provides derivatives or modified nucleic acid sequences of several microorganisms for use in the detection and analysis of said microorganisms. The derivative nucleic acids contain the bases adenosine (A), guanosine (G), T (thymine) and U (uracil or some other non-A, G or T base or base-like entity). Given that microbial nucleic acids do not contain methylated cytosine (C) or other C alterations, all C are converted to U. These sequences are amplified where the U in the derivative nucleic acid is replaced by a T, resulting in a modified sequence with the same number of total bases as the corresponding unmodified microbial nucleic acid sequence but made up of a combination of three bases only: A, G and T. As a consequence of this process the nucleic acids derived from the upper and lower strands of the original dsDNA are no longer complementary and the modified microbial sequences have reduced relative genomic complexity for use in detection and analysis of microorganisms.
Patent CA-2654708-A1 (CA)
Title: Apparatus and methods for wire-tying bundles of objects
Inventor: DOYLE DAVID D
IPC: B65B13/22
Filed: 2003-09-30
Abstract: Systems and methods for threading and feeding a length of wire into a wire-tying track, for withdrawing at least some of the wire from the wire-tying track to tension the wire around one or more objects, and for extracting waste wire from the system. The object of the invention herein being a feed and tension mechanism comprising a feed and tension wheel, an accumulator disk, a primary nip mechanism for frictionally engaging the wire at the contact region between the primary nip and the feed and tension wheel, a drive system having two independently operable motors, and wire guiding devices for directing and routing the wire through the feed and tension mechanism. The present invention may further comprise a supplementary nip mechanism to facilitate the threading of the wire into the mechanism, a wire stripping mechanism for extracting any waste wire from the mechanism, and a series of wire sensing devices in communication with a control system to sequence and control the operational cycles of the system. The feed and tension mechanism further includes a frame that structurally supports the major assemblies and attaches to the wire-tying machine.
Patent CA-2656161-A1 (CA)
Title: Process for the synthesis of o-desmethylvenlafaxine
Inventor: NIDDAM-HILDESHEIM VALERIE
IPC: C07C213/02
Filed: 2007-07-26
Abstract: Provided are processes and intermediates for the synthesis of O- desmethylvenlafaxine.
Patent CA-2656451-A1 (CA)
Title: Composition comprising a retinoid and benzoyl peroxide
Inventor: WILLCOX NATHALIE
IPC: A61Q5/00
Filed: 2007-07-11
Abstract: The invention relates to a composition comprising, in a physiologically acceptable medium, at least one retinoid, dispersed benzoyl peroxide and a gelling system comprising at least two categories of compounds.
Patent CA-2661309-A1 (CA)
Inventor: GUO XIAOYU
IPC: B01D53/86
Filed: 2009-04-03
Abstract: An apparatus and method for achieving increased NO x removal efficiency from an emissions control portion of a fossil fuel fired boiler while controlling ammonia slip provides excess levels of ammonia above those levels conventionally employed in SCR  and/or SNCR applications. The apparatus and methods comprise, in part, use of a NO x reduction system comprising at least one selective catalytic reduction system which receives ammonia in higher amounts than conventional practice from an upstream ammonia injection point, and an ammonia reduction system positioned downstream of one or more ammonia injection points and the NO x reduction system. The excess ammonia achieves increased NO x removal, while the ammonia reduction system contains at least one ammonia destruction catalyst which permits the NO x reduction system to be operated at an increased NO x removal efficiency without a corresponding increase in ammonia slip.
Patent CA-2661594-A1 (CA)
Title: Wire guide sphincterotome
Inventor: BLIND PER-JONAS
IPC: A61B18/14
Filed: 2007-06-12
Abstract: A medical system configured for cannulation of a lumen having a stricture is provided. The medical system includes an elongate sheath having a proximal portion, a distal portion and a first lumen at least partially extending through the sheath. The medical system also includes a wire guide having a cutting portion, a non-cutting tip portion, and a non-cutting shaft portion proximal to the cutting portion. The wire guide extends at least partially through the first lumen and at least a portion of the cutting portion is positionable outside the sheath to cannulate the stricture. A method of cannulating a stricture is also provided.
Patent CA-2662042-A1 (CA)
Title: Shroud segment cooling configuration
Inventor: KAPILA JAIN
IPC: F01D9/02
Filed: 2009-04-08
Abstract: An cooling arrangement for a turbine shroud provides an air stream directed from a passage extending through a radial wall to impinge on a surface in an area of a back side of the turbine shroud, the surface defining a plane which improves the attack angle of the air stream to the surface.
Patent CA-2662538-A1 (CA)
Inventor: BERTANI BARBARA
IPC: A61P25/00
Filed: 2007-09-07
Abstract: The present invention relates to novel compounds of formula (I)´, pharmaceutically acceptable salts, prodrugs or solvates thereof: wherein R1 is hydrogen or C1-4alkyl; R2 is a group A, K or W wherein A is (II) K is an .alpha. or .beta. naphthyl group, optionally substituted by 1 or 2 groups R18, each of them being the same or different; and W is (III) and wherein G is a 5,6-membered monocyclic heteroaryl, or a 8- to 11-membered heteroaryl bicyclic group; such G may be substituted by (R15)p, which can be the same or different; p is an integer from 0 to 5; R3 is selected in the group consisting of: hydrogen, fluorine, and C1-4alkyl; or corresponds to a group X or X1; R4 is selected in the group consisting of: hydrogen, fluorine, and C1-4alkyl; or corresponds to a group X or X1; R5 is hydrogen or C1-4alkyl; R7 is hydrogen or C1-4alkyl; or is a group X, X1, X2 or X3; wherein X is (IV) X1 is (V) X2 is (VI) and X3 is (VII) R6 is hydrogen or C1-4alkyl; or is a group X or X1; R9 is C1-4alkyl; R10 is selected from a group consisting of: hydrogen, halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5; or corresponds to a group R8; R8 is a 5-6 membered heterocycle group, which may be substituted by one or two substituents selected from a group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy and C1-4alkanoyl; R11 is selected from a group consisting of: hydrogen, halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4aIkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5; or corresponds to a group R8; R12 is selected from a group consisting of: hydrogen, halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4aIkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5; or corresponds to a group R8; R13 is selected from a group consisting of: hydrogen, halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5; or corresponds to a group R8; R14 is selected from a group consisting of: hydrogen, halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4aIkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5; or corresponds to a group R8; R15 is selected from a group consisting of: halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5; or corresponds to a group R8; R16 is hydrogen, C1-4alkyl, C3-6cycloalkyl or C3-6cycloalkylC1-3alkyl; R17 is hydrogen or C1-4alkyl; R18 is selected from a group consisting of: halog
Patent CA-2662991-A1 (CA)
Inventor: OROLOGIO FURIO
IPC: F16L59/14
Filed: 2009-04-17
Abstract: A reflective metal polymeric insulation bubble pack assembly comprising a first reflective metal bubble pack; a second reflective metal bubble pack; and a first plurality of intervening bubble spaces suitably located between the first and the second bubble packs as to define at least one inner insulative air chamber between the first and second bubble packs.  The invention provides a non-fiberglass improved R-value insulation material that is cost--effective in material, labour, production and installation costs relative to prior art materials.
Patent CA-2663551-A1 (CA)
Inventor: BACK LUCAS
IPC: A61F13/62
Filed: 2006-09-25
Abstract: Absorbent garment (10), such as a diaper or an incontinence guard, said g arment having a longitudinal (y) and a transverse direction (x) and comprisi ng a first body panel (11), a second body panel (12) and a crotch portion (1 3) therebetween, each of said first and second body panels having a waist po rtion (11a, 12a). The absorbent garment (10) is further provided with belt s ections (14a, 14b) attached to the waist portion (11a) of first body panel ( 11) and is adapted to be wrapped around the waist of the user of the absorbe nt garment (10) and fastened together by means of first fastening means (17) . The second body panel (12) at its waist portion (12a) is provided with sec ond fastening means (19) adapted to be fastened to at least one of the belt sections (14a, 14b) in such a way that the absorbent garment (10) will assum e a pant-like shape. When tested on Cyclic Waist Expansion Test apparatus (2 5), as described herein, the absorbent garment (10) does not slip down more than 15 cm from its initial position on the Cyclic Waist Expansion Test appa ratus (25) during at least ten expansion/contraction cycles of the Cyclic Wa ist Expansion Test and during at least 30 seconds after being subjected to a t least ten expansion/contraction cycles of the Cyclic Waist Expansion Test.
Patent CA-2663564-A1 (CA)
Inventor: SHAFER GARY MARK
IPC: G06K7/00
Filed: 2007-09-18
Abstract: A method and system for determining the absence and presence of items in an RFlD interrogation zone. At least one RFID reader transmits interrogation signals in an interrogation zone. Each RFID reader transmits interrogation signals having a forward amount of RF energy and receives response signals f rom the items in the interrogation zone having a reflected amount of RF ener gy. A detection circuit determines the presence and absence of items within the interrogation zone based at least in part on the reflected amount of RF energy.
Patent CA-2665476-A1 (CA)
Title: Bicyclic nitrogen-containing heterocyclic compounds for use as stearoyl coa desaturase inhibitors
Inventor: ZABLOCKI JEFF
IPC: C07D241/44
Filed: 2007-10-05
Abstract: The present invention discloses bicyclic nitrogen-containing heterocyclic compounds for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, oily skin conditions, metabolic syndrome, and the like.
Patent CA-2666781-A1 (CA)
Inventor: LEPENDU JACQUES
IPC: C07H15/14
Filed: 2007-10-18
Abstract: The invention relates to .alpha. -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the .alpha.-galactoceramide analogs. The methods of manufacture of the invention involve the use of unsaturated intermediate compounds which enable to synthesize .alpha.-galactoceramide analogs by a mere metathesis reaction. The .alpha. -galactoceramide analogs of the invention are useful as active ingredients of pharmaceutical compositions, particularly in pharmaceutical compositions having anti-cancerous properties.
Patent CA-2669394-A1 (CA)
Title: Electrolysis apparatus, internal combustion engine comprising the electrolysis apparatus, and vehicle comprising the internal combustion engine
Inventor: HALLENBECK JOHN R
IPC: H01M8/02
Filed: 2007-11-12
Abstract: An electrolysis apparatus comprising an enclosure, a first electrode disposed within the enclosure, a second electrode disposed within the enclosure, and at least one electromagnetic energy radiator disposed within the enclosure. The apparatus further comprises a power source external to the enclosure, where the power source is interconnected with the first and second electrodes such that the first electrode compnses a cathode and the second electrode comprises an anode. The apparatus further comprises at least one oscillator external to the enclosure, where each oscillator is interconnected to a different electromagnetic energy radiator. An engine system comprising an electrolysis apparatus interconnected to an internal combustion engine. The electrolysis apparatus cleaves water into a mixture of hydrogen gas and oxygen gas. The mixture of hydrogen gas and oxygen gas is input into, and fuels, the internal combustion engine. A vehicle comprising the engine system
Patent CA-2669533-A1 (CA)
Title: Stretch fabrics with wrinkle resistance and garment
Inventor: LAMIA ALBERTO LORA
IPC: D03D15/56
Filed: 2007-11-30
Abstract: Compositions having good wrinkle resistance and other properties when made into garments that can be made from an ethylene multi-block copolymer. The resulting fabrics and garments often have good chemical resistance, heat-resistances, and are dimensionally stable.
Patent CA-2675437-A1 (CA)
Title: Counter-balanced mold plate for food patty molding machine
Inventor: LINDEE SCOTT A
IPC: A22C7/00
Filed: 2007-09-14
Abstract: A mold plate for use in a reciprocating mold plate patty-forming apparatus includes a flat body having a plurality of cavities for forming patties. The flat body has a fill side face and an opposite face. A grid pattern of grooves is formed on the second face extending longitudinally and laterally on the second face. The pattern extends a lateral distance that is about equivalent to an overall patty cavity field width. Longitudinal and lateral slots that penetrate though a thickness of the mold plate and flow connect fill side pressure and meat with the pattern of grooves on the second face to balance the pressure on the opposite faces of the flat body.
Patent CA-2675849-A1 (CA)
Title: Generation systems and methods for transaction identifiers having biometric keys associated therewith
Inventor: KEANE TIM
IPC: H04K1/00
Filed: 2008-01-11
Abstract: A system for generating transaction settlement identifiers includes an ar rangement configured to receive a biometric sample from a customer and an ar rangement configured to use the biometric sample to select the transaction s ettlement identifier from a pool of predetermined transaction settlements. A mapping arrangement configured to map the selected financial transaction se ttlement identifier to an identifier of the customer also may be included.
Patent CA-2677700-A1 (CA)
Inventor: PRETORIUS CORNELIUS JOHANNES
IPC: B23B27/14
Filed: 2008-02-28
Abstract: The invention provides for a method of machining a workpiece made of a material selected from a metal, metal matrix composite, wood, synthetic, ceramic and stone and synthetic construction materials which includes the step of machining the workpiece using a tool which includes a tool component comprising a layer of polycrystalline diamond (12) having a working surface (16), a softer layer (20) containing a metal and bonded to the working surface (16) of the polycrystalline diamond layer (12) along an interface, the region (22) of the layer of polycrystalline diamond (12) adjacent the interface containing some metal from the softer layer (20).
Patent CA-2678706-A1 (CA)
Inventor: PETRUSON BJOERN
IPC: A61K9/06
Filed: 2008-02-21
Abstract: The invention relates to a gel composition comprising: a) a carboxy polymethylene polymer; b) glycine; c) a source of calcium ions; and d) water. The invention also extends to a dry composition comprising the aforementioned components a), b) and c). The gel compositions of the invention are useful for the prophylaxis and treatment of epistaxis. The gel compositions can be easily administered to the nasal cavity and do not require removal after use.
Patent CA-2679461-A1 (CA)
Title: Method for recognizing content in an image sequence
Inventor: HAUKE RUDOLF
IPC: G06K9/00
Filed: 2008-04-01
Abstract: The invention relates to a method for recognizing content in an image sequence, comprising the steps of: detecting at least one face appearing in at least one frame of an image sequence under test; recognizing characteristic features of said at least one face; comparing said characteristic features to known features of characters stored in a database, thereby deciding whether said face represents a known character; detecting and recognizing at least one additional feature in at least one frame of said image sequence under test and at least one relation between the appearance of said known character and said at least one additional feature; comparing said at least one relation to metadata comprising known relations stored in said database each one assigned to a particular known image sequence, thereby recognizing if said image sequence under test at least partially equals one of said known image sequences.
Patent CA-2680560-A1 (CA)
Inventor: ZHANG JUNTIAN
IPC: A61P15/08
Filed: 2007-12-25
Abstract: The invention discloses the use of ginsenoside Rg1, its metabolites ginsenoside Rh1 and Ppt in preparing pharmaceutical compositions and health care products with the effects of improving sexual function and promoting spermatogenesis of male mammals. The invention further discloses the pharmaceutical compositions and health care products with the above-mentioned effects, which comprise at least an active ingredient selected from ginsenoside Rg1, its metabolites ginsenoside Rh1 and Ppt, and pharmaceutical acceptable excipients.
Patent CA-2680802-A1 (CA)
Inventor: LASSINI STEFANO ANGELO MARIO
IPC: F41G9/00
Filed: 2009-09-24
Abstract: A store management system (SMS) (114) is provided. The SMS includes a manned station including a master arm control message encoder (130), a first critical control message encoder (132), and a second critical control message encoder (134), an unmanned platform including a master arm control message decoder (174), a first critical control message decoder (176), and a second critical control message decoder (178), and a data link (112) between the manned station and the unmanned platform. The data link (112) is configured to transmit a master arm control message (160) from the master arm control message encoder to the master arm control message decoder, transmit a first critical control message (400) from the first critical control message encoder to the first critical control message decoder, and transmit a second critical control message (500) from the second critical control message encoder to the second critical control message decoder.
Patent CA-2681093-A1 (CA)
Inventor: GENTLES ROBERT G
IPC: A61K31/55
Filed: 2008-03-05
Abstract: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using. these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
Patent CA-2682207-A1 (CA)
Title: Quinazolinone derivatives as aldh-2 inhibitors
Inventor: ZABLOCKI JEFF
IPC: C07D239/91
Filed: 2008-04-03
Abstract: Disclosed are novel quinazolinone derivatives, useful as ALDH-2 inhibitors for treating mammals for various disease states, such as treatment for cocaine dependency or alcohol dependency.
Patent CA-2684320-A1 (CA)
Inventor: ENGEL RICHARD
IPC: A43B13/41
Filed: 2007-04-19
Abstract: An athletic shoe particularly suited for kicking sports comprises an outsole, and upper section and an insole. The insole has at least three compressible layers, the outsole has relatively straight inside and outside edges, as well as a grooved bottom surface. The inner and outer sides of the upper section may also be relatively flat. The shoe may further comprise a padded inner tongue and a flat outer tongue.
Patent CA-2684415-A1 (CA)
Inventor: CAUDLE GEORGE
IPC: A61B3/117
Filed: 2000-07-27
Abstract: Improved systems, devices, and methods measure and/or change the shape of a tissue surface, particularly for use in laser eye surgery. Fluorescence of the tissue may occur at and immediately underlying the tissue surface. The excitation energy can be readily absorbed by the tissue within a small tissue depth, and may be provided from the same source used for photodecomposition of the tissue. Changes in the fluorescence spectrum of a tissue correlate with changes in the tissue's hydration.
Patent CA-2685236-A1 (CA)
Inventor: ALLEMAND JAMES S
IPC: G01C9/18
Filed: 2008-05-02
Abstract: A level tool comprising a body and a clamping portion disposed at one end of the body. The clamping portion includes a first arm having a plurality of spaced-apart contact surfaces and a second arm having a fastening member. The first and second arms define an opening for receiving a portion of a workpiece. The plurality of spaced-apart contact surfaces and the fastening member cooperate to releasably clamp the portion of the workpiece received in the opening.
Patent CA-2686754-A1 (CA)
Inventor: JACOBSEN HELMUT
IPC: A61K31/428
Filed: 2008-04-30
Abstract: The invention relates to compounds of formula (I) : wherein hetaryl I is formula (II); hetaryl II is formula (III); or to pharmaceutically active acid addition salts. It has been found that the present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of .beta.-amyloid in the brain, in particular Alzheimer's disease.
Patent CA-2687134-A1 (CA)
Title: Sliding friction reducer
Inventor: HOLCOMB GREGORY JON
IPC: A47B96/00
Filed: 2008-05-07
Abstract: A friction reducer is positioned between a bar component and a channel in which an edge of the bar is enclosed during relative motion between the bar and the channel. The friction reducer is made of a material that presents a lower friction surface upon which the relative motion occurs.
Patent CA-2687602-A1 (CA)
Inventor: ROTH-CHIARELLO MICHAEL
IPC: A61K38/22
Filed: 2008-05-19
Abstract: La présente invention porte sur de nouveaux peptides qui possèdent une forte activité biologique et pharmacologique en tant qu'agents thérapeutiques pour le traitement de nombreuses maladies pulmonaires ou maladies liées aux poumons et/ou aux bronches, notamment la broncopneumopathie chronique obstructive (COPD), la fibrose kystique (CF) et la bronchiolite oblitérante (BO). Les peptides synthétiques selon l'invention sont des dérivés de peptide intestinal vaso-actif (VIP) et présentent des propriétés physiques, pharmacologiques et biologiques/thérapeutiques améliorées par comparaison avec le VIP.
Patent CA-2687786-A1 (CA)
Inventor: O'CONNOR MARK JAMES
IPC: A61P35/00
Filed: 2008-05-23
Abstract: A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose)polymerase (PARP) inhibitor, or a pharmaceutically acceptable salt thereof is described.