baber/WOPTO huggingface dataset:
Patent DO-P2006000117-A (DO)
Title: Terapia génica de interferon-beta usando un sistema mejorado de expresión regulada
Inventor: BAUZON MAXINE
IPC: A61K31/70
Filed: 2006-05-18
Abstract: Sistema mejorado de expresión para la expresión regulada de una proteina codificada o una molecula terapeutica de acido nucleico en las celulas de un sujeto, para usar en el tratamiento de enfermedades. En particular, en la presente invención se provee un sistema mejorado de expresión genetica regulada, y composiciones farmaceuticas y usos de estas para el tratamiento de enfermedades.
Patent DO-P2010000072-A (DO)
Title: Activadores de guanilato ciclasas solubles
Inventor: BITTNER AMY R
IPC: C07D403/04
Filed: 2010-03-05
Abstract: Un compuesto que tiene la estructura util para el tratamiento o prevencion de enfermedades cardiovasculares, disfuncion endotelial, disfuncion diastolica, aterosclerosis, hipertension, angina de pecho, trombosis, reestenosis, infarto de miocardio, apoplejias, insuficiencia cardiaca, hipertonia pulmonar, disfuncion erectil, asma bronquial, insuficiencia renal cronica, diabetes, o cirrosis del higado en un paciente humano o animal.
Patent DO-P2010000331-A (DO)
Title: Formulacion de medicamento solida con liberacion retardada
Inventor: KANIKANTI VENKATA-RANGARAO
Filed: 2010-11-05
Abstract: La invención se refiere a una preparación de medicamento sólida con liberación retardada de principios activos, que es adecuada especiaimente para la uso en animales.
Patent DO-P2017000144-A (DO)
Title: Síntesis total de trioxacarcina dc-45-a2 y preparación de análogos de trioxacarcina
Inventor: KYRIACOS C NICOLAOU
IPC: C07H17/04
Filed: 2017-06-19
Abstract: En un aspecto, la presente invención proporciona derivados novedosos de análogos de trioxacarina de la fórmula (I) (I) 		en donde las variables son como se define anteriormente. La aplicación también proporciona composiciones, métodos de tratamiento, y métodos de síntesis de los mismos.
Patent EC-SP10010556-A (EC)
Title: Piridinas y pirazinas como inhibidores de pi3k
Inventor: BRUCE IAN
IPC: A61K31/4427
Filed: 2010-10-19
Abstract: La presente invencion se refiere a un compuesto de la formula (I); o una sal, de una manera adecuada una sal farmaceuticamente aceptable, o un solvato del mismo, en donde los grupos R1, R2, Ar', A e Y se definen en la descripcion, a composiciones y al uso de los compuestos en el tratamiento de condiciones inflamatorias y alergicas.
Patent EC-SP11011370-A (EC)
Title: Identificación y autenticación usando marcados de material de cristal líquido polimérico
Inventor: MARGUERETTAZ XAVIER AUGUSTO
IPC: G06V30/224
Filed: 2011-10-03
Abstract: La presente invención se refiere a un marcado de material de cristal líquido polimérico con unas determinadas características ópticas que permiten su autenticación y lectura mediante una máquina y su autenticación por el ojo humano. El marcado se aplica en un objeto, mercancía o artículo mediante un proceso de impresión de información variable. El marcado tiene la forma de indicios que representan un código único que permite tanto una autenticación fácil por el ojo humano como un seguimiento y rastreo seguros del objeto, mercancía o artículo marcado a lo largo de todo su ciclo de vida.
Patent EC-SP12011597-A (EC)
Title: Forma de dosificación de liberación controlada extruida por fusión en caliente
Inventor: GALIA ERIC
IPC: A61K31/137
Filed: 2012-01-11
Abstract: La invención se refiere a una forma de dosificación de liberación controlada extruida por fusión en caliente que presenta una mayor resistencia a la rotura (resistencia a la compresión). La forma farmacéutica se caracteriza por un perfil de liberación modificada del compuesto activo farmacológicamente contenido.
Patent GB-189700353-A (GB)
Title: Apparatus for Indicating When Water Levels Fall below a Predetermined Level.
Inventor: DELMARD MAURICE
Filed: 1897-01-06
Granted: 1897-07-17
Abstract: 353. Delmard, M. Jan. 6. Water levels, indicating.-The apparatus is for sounding an electric bell or actuating an indicator on the water falling below a predetermined limit. In a casing A, closed by an apertured disc D and flexible bellows F (or a flexible diaphragm), is an insulated socket B, through which works a rod C attached by a chain N to the float G. A piece H, at the end of the rod C, is brought down into contact with the plate I (so as to close circuit with the bell) by a spring when the water falls to a certain point.
Patent GB-189702925-A (GB)
Title: Improvements in or relating to Devices for Tightening Belts or other Driving Gear in Self-propelled Vehicles.
Inventor: CROWDEN CHARLES THOMAS
Filed: 1897-02-03
Granted: 1898-01-08
Abstract: 2925. Crowden, C. T. Feb. 3. Axle-trucks or undercarriages.-In order to tighten the driving-belt or the like in self-propelled vehicles, the driving-wheel bearing-springs are attached to a frame, the ends F<1> of which slide on the frame of the vehicle, and which can be adjusted in position by the bolt H. A stay of adjustable length connects the axle with the driving-shaft.
Patent GB-189712114-A (GB)
Title: Improvements in Apparatus for effecting Interchange of Temperature between Fluids or for Heating and Evaporating Liquids.
Inventor: FRANK SALOMON
Filed: 1897-05-15
Granted: 1898-03-26
Abstract: 12,114. Frank, S. May 15. Cooling gases and liquids.-An apparatus for effecting interchange of temperature between fluids is made up of a series of stamped plates a, b connected at their edges a<2>, b<2>, and provided with projections c bearing against each other to prevent distortion. The plates are provided with projecting nipples d<1>, d<2> adapted to fit over one another when one of a pair of similar plates is reversed, and a number of these elements are connected together to form the complete apparatus. The fluid to be treated flows through the apparatus in the direction indicated by arrows, and the attemperating -fluid circulates around the apparatus.
Patent GB-189719525-A (GB)
Title: Improvements in Interchangeable Garden Tools.
Inventor: SIMMONS ELBERT OSMAN
Filed: 1897-08-24
Granted: 1898-02-05
Abstract: 19,525. Simmons, E. O., and Simmons, E. L. Aug. 24. Handles for hoes, rakes, and other gardening- tools. A socket 2 is secured to a handle 1, and is formed with recesses and set-screws for holding and securing three arms 5, 9, and 10. The said arms carry cultivator tines 13, or a rake head 17, or a hoe blade, or other garden tool.
Patent GB-189800100-A (GB)
Title: Improvements in Cornice Pole and the like Fittings.
Inventor: SHOWELL CHARLES
Filed: 1898-01-03
Granted: 1898-11-05
Abstract: 100. Showell, C., and Baker, F. R. Jan. 3. Curtains, drawing and suspending.-The pole is made of tubular parts 4, 5, 6, separated by spheres 9 of slightly larger diameter than the tubes, all strung on a more or less flexible wire cord or rod 10 which is screw-threaded at the ends to receive knobs 11. The rod &c. 10 can be bent to the shape of the window, when the tubes and spheres are threaded on it.
Patent GB-189800255-A (GB)
Title: Improvements in Hydrants, Stop Valves, and the like.
Inventor: HUDSON GB JAMES CADOUX
Filed: 1898-01-04
Granted: 1898-12-10
Abstract: 255. Hudson, J. C. Jan. 4. Hydrants.- Stop valves for hydrants and the like are let into the main, as shown in Fig. 1 for example, so that they shall offer as small an external projection or obstruction as possible. The main is enlarged round the valve so that the waterway is not reduced.
Patent GB-189802346-A (GB)
Title: Improvements in and relating to Inflators for Pneumatic Tyres and Clips for Carrying the same.
Inventor: HANLON WILLIAM
Filed: 1898-01-29
Granted: 1898-12-03
Abstract: 2346. Hanlon, W. Jan. 29. Inflating.-The pump shown in Fig. 1 is described in the Provisional Specification. The flexible connecting-tube is pushed into the hollow piston-rod when not in use, and is blown out again when pumping begins. It contains springs E for distending it between the supporting-studs A on the velocipede frame X. It may have a foot attachment.
Patent GB-189803765-A (GB)
Title: Improvements in Forks, or Implements for Elevating Hay, Straw, or the like.
Inventor: OGLE WILLIAM
Filed: 1898-02-15
Granted: 1898-12-23
Abstract: 3765. Ogle, W. Feb. 15. Lifting-dogs for hay, straw, and the like. The tines A have pivoted blades D with cutting or serrated edges. The blades, when in line with the tines, are inserted into the straw &c. and turned by the handle F<2> and its connections F, F', E into the locked position shown in Fig. 1. The frame B is then lifted to the desired height by a crane or tackle. By pulling the cord G', the spring catch G is released and allows the load to fall and the blades to assume their original positions. In a modification, the blades D form the lower ends of the tines, which are provided with pivoted arms operated by the means shown in Fig. 1. The Provisional Specification states that the blades may be telescoped in the tines.
Patent GB-189808869-A (GB)
Title: Improved Hand Shears for Cutting Tin and Zinc Sheets, Wire-work, and such like.
Inventor: HAUGK GUSTAV
Filed: 1898-04-16
Granted: 1898-05-20
Abstract: 8869. Haugk, G. April 16. Shears for cutting metal sheet or wire. The handles are vertical, but bend round to horizontal blades which are jointed to them and to each other, while the handles themselves are jointed together. A spring is interposed between the handles, and a pencil and tape measure are put on them.
Patent GB-189820440-A (GB)
Title: Improvements in Alternating Current Measuring Instruments.
Inventor: DAVIS HARRY PHILLIPS
Filed: 1898-09-27
Granted: 1899-07-29
Abstract: 20,440. Davis, H. P., and Conrad, F. May 7, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Current meters for alternating currents. A laminated electromagnet 6 is excited by current supplied to a coil 8. Closed-circuit coils 9 surround parts of its poles, the currents induced in them producing a shifting of the magnetic field in the air-gap of the core 6, and turning a conducting-disc 10, carried by a shaft 11, in opposition to a spiral spring 16. The shaft carries a pointer 14 over a graduated circular dial 15. The spring 16 is attached to the shaft and to an adjustable slotted plate 17. The disc moves in the field of a permanent magnet 18, to damp oscillations. The edge of the disc is spiral in form, so that as it turns it gradually leaves the field of the electromagnet 6, to enable a uniformly-divided scale to be used. The disc is balanced by slotting and weighting it. When the instrument is used for measuring current strength, the coil 8 is connected with the ends of a non - inductive resistance having a temperature resistance coefficient at least as high as that of the disc 10. For measurement of electromotive forces, the coil 8 is connected in series with a non-inductive resistance with a low coefficient ; a small closedcircuit coil having a high coefficient surrounds one pole of the core 6, to produce a demagnetizing effect which diminishes as the temperature of the coil rises. These devices compensate for the diminished conductivity of the disc 10 when its temperature rises, and for changes of frequency.
Patent GB-189823829-A (GB)
Title: Improvements in Forks and Ball-bearings for Cycles.
Inventor: DUNLOP JOHN BOYD
Filed: 1898-11-12
Granted: 1899-10-21
Abstract: 23,829. Dunlop, J. B., and Dunlop, J. B. Nov. 12. Motor road vehicles.-The steering-wheel axle E of a bicycle, tricycle, or motor vehicle is carried in links D pivoted on arms B fixed to the fork A. Springs F are interposed between the links and arms. The springs may be arranged below the axle, in which case the links D are placed above the arms B. The axle E is tapered to fit into eyes in the links, or is otherwise detachably fixed thereto. The pivots of the links are preferably fitted with ball bearings as shown in Fig. 2. The cups G<4> are formed on or fixed in the links. The cone G<3> is fixed to the bolt G, which screws into the cone G<1> carried by, and immovably secured to, the arm B. The bolt is fixed in the arm by a nut G'. The bearings may be placed in the arm B, and the bolt fixed to the link D. The cups, whether formed in the links or made separately, are hardened on the inside only by threading them on a bolt and filling them with charcoal before heating them in the case-hardening furnace. According to the Provisional Specification, the fork blades may be extended in front of, or below, the axle to carry the links. In this case the arms B are dispensed with, the springs being connected at one end to the fork blades.
Patent GB-189826103-A (GB)
Title: Improvements in Presses for Making Golf and other Balls.
Inventor: SMITH WILLIAM HARVEY
Filed: 1898-12-10
Granted: 1899-11-11
Abstract: 26,103. Smith, W. H. Dec. 10. Moulding golf balls &c. - A spherical mould is built up of three or more circumferential sections 2 arranged between top and bottom sections 3. Conical or rounded surfaces 4 of the sections 2 bear against similar surfaces 6 of the end sections 3, and guide-pins 12 of the end sections enter slots 13 in the sections 2. The mould is closed about the material by forcing the end sections towards one another.
Patent GB-189906050-A (GB)
Title: Improvements in Apparatus for Sifting, Sorting, and Classifying Tea or other Products or Materials.
Inventor: JACKSON WILLIAM
Filed: 1899-03-20
Granted: 1899-05-27
Abstract: 6050. Jackson, W. March 20. Sifting tea &c.-Relates to apparatus for sifting, sorting, or classifying tea or other products or materials. The sieves D receive a reciprocating motion through the rods E, which are connected to cranks 0 attached to a rotating shaft B. The sieves are carried by blade springs G secured to brackets H. At the driving end of the sifter the springs are connected directly to the sieves by a joint J, and at the other end the sieves are connected to locking-devices L which slide upon bars K, secured to the springs, so that the sieves may be adjusted to any desired inclination. The wirework of the sieve is attached to frames M. Scrapers N, in contact with the underside of the wirework of each sieve, are secured to the rods 0 mounted in bearings. The scrapers N may be moved to clear the sieve by means of the rod R. The scraper may be secured to the sieve by locking-devices such as bolts S passing through brackets s<2> secured to the frame M.
Patent GB-189910344-A (GB)
Title: Improvements in Tandem Bicycles.
Inventor: ATKINS NAPOLEON EDWIN WILLIAM
Filed: 1899-05-16
Granted: 1900-03-24
Abstract: 10,344. Atkins, N. E. W. May 16. Convertible tandem bicycles.-In the tandem form, the bicycle is fitted at the rear with a double triangular frame c, e, g carrying the rear saddle k and jointed to the front saddle lug a and bearings i. The rear rider actuates cranks on an axle j passing loosely through the driving-wheel hub and geared with the usual crank axle w by a chain v. The front rider drives through the usual gearing. The tubes e, g are made larger in the middle to give increased strength. The rear frame c, e, g is detachable, and may be replaced by an ordinary fork, thus forming a single bicycle.
Patent GB-189915683-A (GB)
Title: Improvements in Sticks for Umbrellas and Sunshades.
Inventor: KINZETT JAMES HARWOOD
Filed: 1899-08-01
Granted: 1900-05-26
Abstract: 15,683. Kinzett, J. H., and Eeles, F. R. S. Aug. 1. Umbrella &c. sticks.-In umbrellas and sunshades, in order to reduce bulkiness where the ribs and stretchers close upon the sticks, the sticks at these parts are made of a square or octagonal form with flat or concave surfaces.
Patent GB-189916160-A (GB)
Title: Improvements in and relating to Mud-guards for Cycles.
Inventor: STEVENS WILLIAM JAMES
Filed: 1899-08-08
Granted: 1900-07-07
Abstract: 16,160. Stevens, W. J., Harrold, H. E., and Bluemel, F. R. Aug. 8. Guards, mud, for bicycles &c. Relates to clips &c. for attaching stays to the axle plates and mud guards. The stays 4, 4 are formed from a single bar bent at The middle, the bent part being T-shaped to engage a raised portion 14 on the plate 5, Fig. 2, or r rectangular to hook under a lip as shown in Fig. 4. The plate 5 is fixed to the axle by the clamping - nut. I n an other arrangement, the stays carry a collar with projections which engage under the recessed edges of a stud. In a further modification, the ends of the stays fix in a rectangular case on the axle and are held in place by a pin carried on a spring. The outer ends of the stays fit in grooves 19, Fig. 12, in the bridge-piece 18 fixed to the guard, or are bent to form spring tongues 13, Fig. 13, which engage sockets fixed on the bridgepiece 3. In another arrangement, the bridge-piece carries spring clips which engage the ends of the stays. The Provisional Specification describes modified arrangements of clips for holding the stays.
Patent GB-189916311-A (GB)
Title: Improvements in or connected with Dry Core Electrical Cables.
Filed: 1899-08-10
Granted: 1900-06-30
Abstract: 16,311. Savage, H., and Henley's Telegraph Works Co., W. T. Aug. 10. Cables.-Dry-core cables are built up containing a central or other strand covered with rubber or other non-hydroscopic material to facilitate testing &c.
Patent GB-189917766-A (GB)
Title: Improvements in or in connection with Hand Trucks.
Inventor: HEBLETHWAITE JOHN HERBERT
Filed: 1899-09-02
Granted: 1900-09-01
Abstract: 17,766. Heblethwaite, J. H. Sept. 2. Hand-trucks.-Relates to wheel-locking devices for railway platform and other hand-trucks. The application to a truck of the type disclosed in Specification No. 24,407, A.D. 1898, is described. Fig. 3 shows an underside plan of part of such a truck. The inner sides of the wheels B have projections C between which guided bars D are placed by the spring rod E and links G when the traction handle, not shown, is released. In trucks with pivoted T handles, the wheels are locked when a handle is dropped.
Patent GB-189918163-A (GB)
Title: An Improved Bread Cutting Machine.
Inventor: STEFFENHAGEN AUGUST
Filed: 1899-09-08
Granted: 1899-10-21
Abstract: 18,163. Steffenhagen, A. Sept. 8. Bread cutters.-The loaf is laid upon a slightlyinclined tray on feet a, and is pushed by hand through a frame c at one end, where it is cut by a blade on an arched hand-lever f. A gauge plate on a sliding rod i determines the thickness of the slice, and is rocked at each cut to let the slices fall, being connected by a wire n to a lever g under the hand-lever.
Patent GB-189919918-A (GB)
Title: Improvements in Purifiers applicable for Steam Boilers and other purposes.
Inventor: SLACK JOHN EDWARD
Filed: 1899-10-04
Granted: 1900-09-08
Abstract: 19,918. Slack, J. E. Oct. 4. Feedwater, purifying.-In apparatus for separating solid impurities contained in boiler feedwater and other liquids, in which baffle-plates are provided to form a series of settling-spaces, the baffle-plates C, or those of them which extend to the bottom of the cylindrical chamber of the purifier, are mounted on a spindle D which can be turned on its axis so as to invert the plates and leave a continuous space along the bottom of the chamber for blowing out the sediment. The water is admitted at G, and withdrawn at H ; F is a steam inlet.
Patent GB-189923371-A (GB)
Title: Improvements relating to Switches, specially applicable to Switches for Electromotors and the like.
Inventor: SLOAN ROBERT ALEXANDER
Filed: 1899-11-23
Granted: 1900-10-06
Abstract: 23,371. Sloan, R. A., and Barnes, J. E. L. Nov. 23. Switches; cut-outs.-Relates to motor switches in which the main and regulating switches interlock, such as described in Specification No. 1044, A.D. 1899. Electromagnetic devices are arranged to open the main switch in case of overload, or under load. Mechanism is also provided for preventing the handle of the resistance switch from being moved too rapidly. Figs. 1 and 3 show one construction. The handle f is loosely connected to the main contact-bars a through the levers d, one of which is fitted with a curved piece i, which interlocks with the piece j carried by the arm g of the resistance switch. The fixed contacts bare hollow, and contain plungers k which tend to force away the contacts a. These plungers are retained in position by pins n, which are held by detents r, p connected to toggle devices under the control of the maximum and minimum magnets M, N, the armatures of which are undercut and rest on knifeedge supports. To prevent too rapid movement of the handle g, the knob 8 contains a double pawl 6, Fig. 8, which engages with teeth on a curved bar 5. In a modified arrangement, Fig. 10, the spring plungers are omitted, and the switch is held closed by friction, the pressure on the contacts being increased by means of a toggle arrangement 18, 19, 22, 23 controlled by the cut-out electromagnets. When the magnets operate, the pressure on the contacts is removed, and the spring 12 throws back the lever 13.
Patent GB-190007674-A (GB)
Title: A New or Improved Machine for Cleaning Forks and for Cleaning Grinding and Sharpening Knives.
Inventor: BORNI IGNATZ
Filed: 1900-04-25
Granted: 1901-04-25
Abstract: 7674. Borni, I. April 25. Sharpening.-A cast-iron frame, clamped to a bench or table by a screw E, carries bearings in which a square spindle F is rotated by a crank handle through the gearing shown. This spindle has mounted on it a fork-cleaning device G, knifegrinding and sharpening devices H and I, and a knife-cleaning device J. The fork-cleaning device consists of a number of discs 5 of leather or like material pressed together by springs. Each alternate disc is of larger diameter than the adjoining ones, and rotates between the prongs of the fork. The knife-grinding device consists of a pair of emery or similar discs 13 and 14 having wedgeshaped projections 15 on their inner faces separated by similar spaces 16 as shown in Fig. 2. The projections on one disc fit between those on the other, producing an interrupted V-groove in which the knife is ground. The disc 14 is made thicker than the other, to provide a peripheral grinding-surface. The knife-sharpening device consists of a pair of steel discs 18 and 19, of similar form to the grinding-discs. The knife-cleaning device consists of a pair of discs 20, 21, between which the knife is moved to and fro. A trough may be provided to feed a polishing powder or composition to the discs.
Patent GB-190007748-A (GB)
Title: A New or Improved Automatic "Clip" for Gripping Round Rope Cables for Haulage or like purposes.
Inventor: SPENCE ROBERT FOSTER
Filed: 1900-04-26
Granted: 1900-06-16
Abstract: 7748. Spence, R. F., and Wallace, J. April 26. Rope grips.- The rope is gripped between the horn A fixed on the spindle B and the fluted conical eccentric roller C.
Patent GB-190015516-A (GB)
Title: Improvements in or relating to Cycle Brakes.
Inventor: FORD CLEMENT
Filed: 1900-08-31
Granted: 1901-08-31
Abstract: 15,516. Ford, C. Aug. 31. Brakes.-A rim brake adapted to be operated by a backward movement or pressure of the rider's body is shown in the Figure. The lever a, provided with the back-rest b, is pivoted to the lower end of the adjusting-arm. The arm passes through and is dependent from the adjustable support f, which comprises the screw-threaded rod passing through the saddle-pin tube, the flanged plugs or washers f<2>, and the nuts f<1>. The connection h between the lever a and the brake is provided with a screw adjustment. According to the Provisional Specification, a tyre brake may be operated by causing a downward thrust on the operating-rod instead of an upward pull.
Patent GB-190023191-A (GB)
Title: Improvements in Furnaces and Flues for Steam Boilers.
Inventor: MEREDITH OWEN
Filed: 1900-12-19
Granted: 1901-10-19
Abstract: 23,191. Meredith, O. Dec. 19. Flues, internal.-The main corrugations a and b are separated by cylindrical or curved portions, these portions being merged into the main corrugations by curves of a radius equal to, or but slightly different from, that of the main corrugations. Ribs d, Figs. 3 and 4, with cylindrical or curved connecting-portions, are formed on the outwardlyprojecting corrugations of these or other forms of corrugated flues.