baber/WOPTO huggingface dataset:
Patent NZ-302955-A (NZ)
Title: Water soluble polymer prodrugs attached to macromolecular molecules, preparation and use thereof
Inventor: GREENWALD RICHARD B
IPC: A61K31/335
Filed: 1996-01-30
Abstract: The present invention relates to high molecular weight non-antigenic polymers to prepare prodrugs of the formula 1 where D is a biologically active moiety selected from taxol, taxane, and taxotere, camptothecin, etoposide and podophyllotoxin M is X or Q where X is an electron withdrawing group Q is a moiety containing a free electron pair positioned five or six atoms from Y' Y and Y' are independently O or S; R is a polyalkylene oxide. Also claimed is a method for preparing the composition and use of the composition as anticancer or antitumor agents.
Patent NZ-328620-A (NZ)
Title: Gas fired steam weed killing apparatus
Inventor: LEWISHAM MARK
IPC: A01M21/00
Filed: 1998-08-25
Abstract: The apparatus 1 has barrow type frame, gas bottles , heat exchanger, battery for gas control and spark ignition, and hose with an applicator to destroy vegetation with hot water or steam.
Patent NZ-328918-A (NZ)
Title: Use of glial neutrophic factor (gdnf) in the treatment of hearing disorders
Inventor: MAGAL ELLA
IPC: A61K48/00
Filed: 1997-02-14
Abstract: The present invention relates generally to methods for preventing and/or treating injury or degeneration of cochlear (and vestibular) hair cells and spiral ganglion neurons (as well as vestibular neurons-Carpa's neurons) by administering glial cell line-derived neurotrophic factor (GDNF). The invention relates more specifically to methods for treating sensorineural hearing loss and vestibular disorders.
Patent NZ-330894-A (NZ)
Title: Key controlled latch; lock release means responsive to operation of second actuator rendering locking means inactive
Inventor: BLANCH DAVID GARFIELD
IPC: E05B13/00
Filed: 1997-02-11
Abstract: A latch assembly (1) of the kind having a latch bolt (3) which is mounted on a casing (5) for relative movement between an extended latching position and a retracted release position.  The bolt is movable into the release position by operation of either one of two actuators (9, 12) which are accessible at inner and outer sides respectively of the latch assembly.  The inner actuator includes a turn-knob or handle (9), and locking means (13, 14) associated with that actuator is operable to prevent operation of the inner actuator and thereby prevent retraction of the latch bolt (3) from the inner side of the assembly.  The assembly includes lock release means (17) which responds to operation of the outer actuator (12) so as to deactivate the locking means (13, 14) and thereby release the inner actuator for normal operation.  The locking means includes a spring loaded cam which influences the position of at least one detent and which is held in a locking means active position by retaining means  which is responsive to operation of the outer actuator.  That response involves the retaining means releasing its influence on the cam member so that it can be driven under the influence of the associated spring into a locking means inactive position.
Patent NZ-333066-A (NZ)
Title: Child safety seat with movable front foot to compress the seat cushion
Inventor: CARINE SHAUN
IPC: B60N2/28
Filed: 1998-11-30
Abstract: This child safety seat comprises a seat body (10) and a base (14), is adapted to be secured on a vehicle seat by a lap strap (20) of a vehicle seat belt.  A front foot (28) is pivotally mounted on the front part of the seat body (10, 14) so as to be movable between a first position and a second position in which it projects downwardly from the seat body (10, 14) to a greater extent that when in its first position so as to compress the front part of the vehicle seat cushion (22).  This reduces the extent of angular movement of the child seat which can take place subsequent to installation, for example during an accident, before the front foot (28) abuts against the rigid structure of the vehicle seat with the maximum possible compression of the seat cushion trapped therebetween.
Patent NZ-334059-A (NZ)
Title: Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
Inventor: KLEIN SCOTT I
IPC: A61K38/00
Filed: 1997-08-15
Abstract: compound of formula VIII is claimed wherein: B is alkyl, cycloalkyl, cycloalkylalkyl, alkylcycloalkyl, alkylcycloalkylalkyl, aryl, aralkyl, alkylaryl or alkylaralkyl; E1 is H; E2 is the a-carbon side chain of a naturally occurring a-amino acid, H, alkyl, cycloalkyl, cycloalkylalkyl, alkylcycloalkylalkyl or optionally substituted aryl, aralkyl, heterocyclyl or heterocyclylalkyl or E1 and E2 taken together with the nitrogen and carbons to which they are attached form a 4-7 membered azacyclolkane ring; G is OR1 or NR1R2; R1 and R2 are independently H, alkyl, cycloalkyl, cycloalkylalkyl, alkylcycloalkyl, alkylcycloalkylalkyl, aryl, aralkyl, alkylaryl or alkylaralkyl; p is 1-4 and P1 is a hydrogenation labile acid protecting group.
Patent NZ-335291-A (NZ)
Title: Neurotrophin antagonist compositions
Inventor: TEHIM ASHOK
IPC: C07D471/06
Filed: 1997-10-20
Abstract: A pharmaceutical composition comprising a compound of Formula I wherein R1 is selected from, inter alia, alkyl, aryl-loweralkyl, heterocycle-loweralkyl, loweralkyl-carbonate; optionally substituted amino; benimidaz-2-yl; optionally substituted phenyl; loweralkyl-(R5)(R6) wherein one of R5 and R6 is selected from H and the other is selected from carboxy, carboxy-loweralkyl and loweralkoxycarbonyl; NHCH2CH2OX wherein X represents an in vivo hydrolyzable ester; and R2 and R3 are independently selected from H, NO2, halo, di(loweralkyl)amino, cyano, C(O)OH, phenyl-S-, loweralkyl, and Z(O)OR7 wherein Z is selected from C and S and R7 is selected from H, loweralkylamino and arylamino; or pharmaceutically acceptable salts or certain in vivo hydrolyzable esters or amides thereof, in an amount effective to inhibit neurotrophin-mediated activity, and a suitable carrier, is described. The compositions are useful to inhibit undesirable neurotrophin-mediated activity such as the neurite outgrowth that occurs in some neurodegenerative disease states.
Patent NZ-507829-A (NZ)
Title: Vaccine adjuvants for immunotherapy of melanoma
Inventor: SHERMAN MATTHEW L
IPC: A61K39/00
Filed: 1999-04-23
Abstract: Use of IL-12 and antigen-presenting cells pulsed with peptide in the preparation of a medicament for inducing a mammalian immune response, wherein the antigen-presenting cells are not dendritic cells, a method of inducing an immune response in a non-human mammal comprising: a) providing a composition comprising IL-12; b) providing a composition comprising IL-12 and said composition comprising antigen-presenting cells pulsed with peptide to a non-human mammal in an amount effective to induce an immune response, wherein the antigen-presenting cells are not dendritic cells, a method of treating a non-human mammal with a disease comprising administering a composition comprising antigen-presenting cells pulsed with peptide wherein the antigen presenting cells are not dendritic cells and a composition comprising IL-12.
Patent NZ-508196-A (NZ)
Title: Dispenser for foldable flexible flat sheets
Inventor: HANNA ALFRED STUART
IPC: B65D83/08
Filed: 2000-11-15
Abstract: A dispenser for flexible sheet material, the dispenser including; a) a casing for storing a plurality of flexible sheets, folded into two or more folded portions such that the sheets nest within each other; b) an aperture in the casing to permit sequential removal of the sheets; and c) at least one spacer formed separately from the casing and adapter to be non-fixedly positioned within the casing between folded portions of the nested sheets for maintaining a predetermined minimum spacing between folded portions such that the sheet curvature at each fold does not significantly hamper each sheet being drawn around the fold in order to remove it through the aperture.
Patent NZ-509735-A (NZ)
Title: Sliding member and piston for internal combustion engine
Inventor: TSUNASHIMA SAKAE
IPC: F16J10/04
Filed: 2000-06-27
Abstract: A sliding member, wherein a protruded part extending in a direction crossing a sliding direction is provided on at least one of the sliding surfaces of sliding members slid with each other, and fine dimples are provided in the surfaces of the protruded part, whereby lubricating oil is retained in the dimples and, in a running-in, the lubricating oil becomes easier to be withdrawn from an inlet part formed by the dimples.
Patent NZ-511442-A (NZ)
Title: Multiparticulate modified release composition for multiple dosing of ADD patients with methylphenidate HCl
Inventor: DEVANE JOHN G
IPC: A61K9/48
Filed: 1999-11-01
Abstract: A multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner is described.  The multiparticulate modified release composition comprises an immediate release component and a modified release component; the immediate release component comprising a first population of active ingredient containing particles and the modified release component comprising a second population of active ingredient containing particles coated with a controlled release coating; wherein the combination of the immediate release and modified release components in operation deliver the active ingredient in a pulsed or a bimodal manner.  Solid oral dosage form containing such a composition is also described. The plasma profile achieved by the multiparticulate modified release composition can reduce patient tolerance to the active ingredient and also increase patient compliance by reducing dosage frequency.  The composition may be useful for the treatment of attention deficit disorder.
Patent NZ-511950-A (NZ)
Title: Nonsteroidal antiinflammatories
Inventor: SKUBALLA WERNER
IPC: C07D265/02
Filed: 1999-11-29
Abstract: The use of compounds of formula (I) for the production of pharmaceutical agents that have an anti-inflammatory action, wherein: R1 and R2 are independently hydrogen, alkyl or together a 3- 7 membered ring, R3 is alkyl or fluorinated alkyl, A is a group of formula (II), B is carbonyl or CH2, and Ar is a ring system selected from the groups of formula (III), (IV), (V) or (VI).
Patent NZ-515264-A (NZ)
Title: Service shut off device
Inventor: PORTER RAYMOND
IPC: F16L/
Filed: 2000-05-05
Abstract: A service shut off device which is a selected length of a composite body adapted to be formed into a shape to fit in use around a service line. The composite body has a flexible casing (20) and a body of intumescent material (28) received in the casing. The body of intumescent material (28) may be continuous. The composite body has means (32) associated with the casing to contain the intumescent material within the casing and means (36) to retain the collar in a selected shape around the service line. Mounting brackets (36) can clip onto the body or be part of the body.
Patent NZ-515485-A (NZ)
Title: Bending wave loudspeaker with a constraint coupled to a discrete region of the panel to which a transducer is also coupled
Inventor: BANK GRAHAM
IPC: H04R31/00
Filed: 2000-07-06
Abstract: A loudspeaker is made of a panel (1) supporting bending waves and a transducer (3) covering a substantial portion of the panel surface.  At least one constraint 11, for example a clamp or a mass, is fixed to the panel. Each constraint reduces the mobility of a small area of the panel.  Excitation of the transducer excites bending waves in the panel; the constraints discourage simple motion and encourage the production of a plurality of bending waves instead.  The constraints can constrain the panel to be excited to produce a good distribution of resonant bending wave modes.
Patent NZ-517340-A (NZ)
Title: Guide post and foot member
Inventor: TURNER PETER GEOFFREY
IPC: E01F9/677
Filed: 2002-02-21
Abstract: A mounting means for a post comprising an in-ground fitting adapted for insertion into the ground at or near ground level and a retaining means adapted to cooperate with said in-ground fitting for removable engagement therewith wherein said in-ground fitting for removable engagement therewith wherein said retaining means is adapted for mounting said post, wherein said in-ground fitting includes a ground penetrating projection and a top platform for slidable engagement with said retaining means.
Patent NZ-520588-A (NZ)
Title: Protease inhibitors
Inventor: CUMMINGS MAXWELL D
IPC: A61P19/08
Filed: 2001-03-07
Abstract: Disclosed herein are C1-6alkyl-4-amino-azepan-3-one protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof that inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, intermediates of such compounds. These protease inhibitors are useful for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease; and parasitic diseases, including malaria.
Patent NZ-524258-A (NZ)
Title: Re-locatable partial discharge transducer head from one transformer to another with only a brief outage
Inventor: UNSWORTH JOSEPH
IPC: H01F27/40
Filed: 2001-08-22
Abstract: An apparatus for detecting partial discharge in electrical equipment, comprises: an electrically insulating elongate member (13); an ultrasonic transducer means (11) mounted to the elongate member (13) for detecting an ultrasonic pulse or wave generated by the occurrence of a partial discharge in the equipment and outputting a signal corresponding to this detection to a signal processing and analysing means; and a transducer means (17) for detecting at least the radio frequency (RF) pulses or waves generated by the occurrence of a partial discharge in the equipment and outputting a signal corresponding to this detection to a signal processing and analysing means; wherein the elongate member is mountable within a support means that is in turn mountable to the electrical equipment such that at least the ultrasonic transducer means is positioned within the equipment and the elongate member extends through the support means to an end distal the ultrasonic transducer positioned external the support means.
Patent NZ-526052-A (NZ)
Title: Azimuthal control of a wind-energy turbine during a storm by simultaneous adjustment of housing and rotor blades
Inventor: WOBBEN ALOYS
IPC: F03D11/00
Filed: 2001-11-15
Abstract: A method is provided for controlling a wind-energy turbine and a wind-energy turbine for carrying out said method, whereby in extremely high winds, said wind-energy turbine is capable of reducing the mechanical stress caused by said winds to the greatest possible extent. To achieve this, the rotor of the wind-energy turbine is set in a first predetermined position, when a first predetermined wind speed, (disconnection speed, limiting speed), greater than 20 m/s is reached and when a second predetermined wind speed, which is significantly higher than the first predetermined wind speed, is reached, the pod (12) is brought into a predetermined azimuthal position.
Patent NZ-529741-A (NZ)
Title: Imidazole derivatives for modulating sodium channels
Inventor: BIGG DENNIS
IPC: A61P25/28
Filed: 2002-06-14
Abstract: Use of a compound of formula (I) or of a pharmaceutically acceptable salt of this compound for preparing a medicament intended for a condition selected from the group consisting of the treatment or prevention of pain, the treatment of epilepsy, the treatment of cardiac rhythm disorders, the treatment of disorders linked with neurodegeneration, the treatment of depression and bipolar disorders and the treatment of irritable bowel syndrome is disclosed, wherein: R1 is selected from the list consisting of a linear or branched alkyl radical containing from 3 to 16 carbon atoms, a cycloalkylalkyl radical the cycloalkyl radical of which contains from 3 to 7 carbon atoms and the alkyl radical of which is linear or branched and contains from 1 to 6 carbon atoms, an aralkyl radical and a substituted aralkyl radical, where the substituted aralkyl is substituted from 1 to 3 times on the aryl group by substituents independently chosen from the list consisting of a halogen atom, a linear or branched alkyl containing from 1 to 6 carbon atoms and a linear or branched alkoxy radical containing from 1 to 6 carbon atoms; R2 is selected from the list consisting of a phenyl radical a substituted phenyl radical, a biphenyl radical and a substituted biphenyl radical, where the substituted phenyl radical is substituted from 1 to 3 times by one or more substituent independently chosen from the list consisting of a halogen atom, a linear or branched alkyl containing from 1 to 6 carbon atoms and an alkoxy radical containing from 1 to 6 carbon atoms, and where the substituted biphenyl is substituted from 1 to 4 times by one or more substituents independently chosen from the list consisting of a halogen atom, a linear or branched alkyl containing from 1 to 6 carbon atoms and a linear or branched alkoxy radical containing from 1 to 6 carbon atoms; and R3 represents a hydrogen atom or a linear or branched alkyl radical containing from 1 to 6 carbon atoms.
Patent NZ-532359-A (NZ)
Title: Tray container for use with cuttings
Inventor: ROGERS ALAN
IPC: A01G9/10
Filed: 2004-04-16
Abstract: A compartment for use with plant cutting, the compartment having a top opening and a smaller bottom opening, with the distance between the openings defining the depth of the compartment. Each compartment having an internal wall, wherein at least a section of the wall is tapered towards the bottom opening, the internal wall including a plurality of root guides, each guide comprising a downwardly orientated ridge and a lateral wall segment that extends along at least a portion of the ridge at or near the apex of the ridge, the internal wall of each compartment also including a plurality of downwardly orientated elongate slots, the slots being located between the apexes of ridges.
Patent NZ-534534-A (NZ)
Title: Virucidal disinfectant
Inventor: LICHTENBERG FLORIAN
IPC: A61K8/00
Filed: 2003-01-16
Abstract: Disclosed is a non-therapeutic use of an aldehyde-free disinfectant composition as a virucidal agent, comprising: (a) an amine and/or quaternary ammonium salt of formula (Ia) or (Ib), wherein: R1 is alkyl, R2 is benzyl or alkyl, R3 is alkyl or -[(CH2)2-O]nR6 where n = 1-20, R4 and R5 are independently alkyl, R6 is H or optionally substituted phenyl, and A- is a monovalent anion or one equivalent of a polyvalent anion of an inorganic or organic acid, and (b) at least one alkanolamine of formula (II), wherein: n and if present, m and o independently are 2 or 3, and x and y independently are 0 or 1.
Patent NZ-539391-A (NZ)
Title: Squeeze-bottle of liquid medicine with self-sealing closure
Inventor: PERRY TIMOTHY
IPC: B65D1/32
Filed: 2003-12-05
Abstract: A bottle (2) of liquid medicine has a self-sealing closure in its neck (14), the bottle being flexible such that when it is inverted or tilted downwardly, squeezing the bottle produces a flow of liquid medicine through the closure, and releasing the bottle terminates the flow of liquid medicine. The bottle is shaped so as to assist the operation, being of generally box-form, having side walls (6, 8) which support larger front and rear panels (10), which can be controllably flexed.
Patent NZ-540056-A (NZ)
Title: Automatic changeover regulator, typically for LPG
Inventor: OLDS CHARLES M
IPC: G05D16/06
Filed: 2003-12-09
Abstract: A pressure regulator (10) includes a changeover regulator (12) with plural inlets (not shown). Inside the regulator, each inlet has a closure member (62) connected to a diaphragm (100) for control of the closure members (62) in response to pressure inside the regulator (12). Biasing members (56) are stabilized in position by either an apertured plate (102), a cup (104) or both. A changeover handle (19) depresses one spring (56) or the other to bias one closure member (62) open to admit gas from the associated inlet.
Patent NZ-545146-A (NZ)
Title: Near-critical fluid fractionation process for extracting plant or animal material
Inventor: CATCHPOLE OWEN JOHN
Filed: 2006-02-07
Abstract: A process for fractionating the constituents of a solution obtained by extracting plant or animal material with an aqueous-organic solvent where the aqueous-organic solvent is a mixture of water and a water-miscible organic solvent, generally including the steps of: (a) contacting the solution with a near-critical fluid to produce a raffinate phase containing high polarity constituents and water, and a near-critical fluid phase containing low to medium polarity constituents; (b) separating the near-critical fluid phase from the raffinate phase; and (c) recovering the low to medium polarity constituents from the near-critical fluid phase and the high polarity constituents from the raffinate phase.
Patent NZ-554781-A (NZ)
Title: A method for standardising a spectrometer
Inventor: JUHL HENRIK VILSTRUP
IPC: G01J3/453
Filed: 2005-12-16
Abstract: A computer-implemented method for adjusting the wavelength scale of an optical spectrum of a sample of interest recorded by a spectrometer is provided. The method includes: providing an optical spectrum recorded by the spectrometer and comprising spectral patterns originating from atmospheric air in the spectrometer; selecting from the provided optical spectrum a spectral pattern originating from a constituent of the atmospheric air; determining a wavelength dependent position value associated with the selected spectral pattern; and adjusting a wavelength scale of the optical spectrum of a sample of interest recorded by the spectrometer based on a difference between the determined value and a corresponding reference value of the selected spectral pattern. An infrared spectrometer implementing this method is also provided.
Patent NZ-555255-A (NZ)
Title: Universal cutting device for portable trimmers
Inventor: CORREIA DE SA PORTOCARRERO MARCO PAULO
IPC: A01D34/73
Filed: 2005-10-18
Abstract: A cutting device to be used with portable trimmers, the cutting device comprising two or more metallic blades 2 that are rotatably connected to a rigid body 1, where the cutting angle of the metallic blades 2 varies automatically depending on the balance between the centrifugal and cutting forces acting on the metallic blades 2. The rigid body 1 has an axially symmetric fixing system so that either side can couple to a commercially available trimmer. Each metallic blade is rotatably connected to the rigid body by a connection that includes at least two bushes, with the first bush 3 made of a friction resistant material and fixed to the rigid body, and a second bush 4 made of a less friction resistant material than the metallic blade 2 or the first bush 3.
Patent NZ-561813-A (NZ)
Title: Cream cheese dispensable from pressure can
Inventor: JAYARATNAM SUMA
Filed: 2007-09-21
Abstract: A cream cheese composition that does not require refrigeration and can be dispensed from a pressurized can is an acidified composition including a cheese component of natural or analog cheese, a condensed phosphate emulsifier such as sodium acid pyrophosphate or sodium hexametaphosphate, dispersed within the cheese component, and other additives such as milk or water and so on, different from the condensed phosphate emulsifying system. The condensed phosphate system and the one or more additional additives are added in an amount sufficient to ensure that the pH of the composition is less than or equal to 4.8.