baber/WOPTO huggingface dataset:
Patent ES-2548299-B2 (ES)
Title: Firma de microARN como indicador del riesgo de recurrencia temprana en pacientes con cáncer de mama
Inventor: LOZANO CASTRO JOSÉ
IPC: C12Q1/68
Filed: 2014-03-13
Granted: 2016-05-13
Abstract: La presente invención se sitúa en el campo de la oncología y el tratamiento del cáncer. La presente invención incluye métodos para pronosticar el riesgo de recurrencia de tumores de mama empleando la firma de expresión de determinados miARNs. Específicamente, la presente invención se refiere a un procedimiento para determinar el riesgo de recurrencia de cáncer de mama que comprende medir los niveles de expresión de al menos un miARN seleccionado de entre el grupo que consiste en miR-149-5p (SEQ ID NO: 1), miR-10a-5p, (SEQ ID NO: 2), miR-20b-5p, (SEQ ID NO: 3), miR-30a-3p (SEQ ID NO: 4); y miR-342-5p, (SEQ ID NO: 5) en una muestra del tumor, en el que una alteración del nivel de expresión de al menos un miARN en el tumor, con respecto al nivel de expresión en una muestra control, es indicativa de un elevado riesgo de recurrencia del tumor. Además, la presente invención se refiere a herramientas y kits para llevar a cabo el procedimiento de la presente invención.
Patent IE-S86482-B2 (IE)
Title: A balloon catheter
Inventor: O'DEA JOHN
IPC: A61M25/00
Filed: 2013-06-17
Abstract: A balloon catheter (1) comprises and elongated catheter (2) and an inflatable balloon (7) releasably and sealably mounted on the catheter (2) with the catheter (2) extending through the balloon (7). A proximal end of the balloon (7) is sealably secured to a proximal tubular member (20) terminating in a socket (25), which sealably engages a sealing disc (30) sealably and rigidly secured to the catheter (2). A distal end of the balloon (7) is sealably secured to a distal tubular member (22), which releasably and sealably engages a distal end of the catheter (2). The proximal and distal tubular members (20) and (22) are slidably engageable with the catheter (2) to facilitate engaging and disengaging with balloon (7) from the catheter (2). <Figure 1>
Patent AU-2001240744-B2 (AU)
Title: Non-invasive measurement of skin bilirubin level
Inventor: DICK JEAN-MICHEL
IPC: H04N5/44
Filed: 2001-03-01
Granted: 2006-03-16
Abstract: The invention concerns a method and a device for non-invasive measurement of a tissue and in particular of the skin bilirubin level. The inventive device is characterized in that it comprises: a reading head ( 1 ) capable of sending several flashes of various specific wavelengths towards the tissue ( 2 ) to be examined and of receiving and measuring in return the reflected light; a calculator, such as a microprocessor, capable of calculating for each wavelength the amount of reflected light and bring it to a value calculated proportionally to a reference value identical for a predetermined wavelength; and a comparator for comparing the calculated value to a table of reference values.
Patent AU-2001269260-B2 (AU)
Title: Load handling vehicle
Inventor: BROWN DAVID JOHN
IPC: E02F3/28
Filed: 2001-06-27
Granted: 2006-06-15
Abstract: A load handling vehicle having an operator's position, a power operated load handler including a boom pivotally mounted at a front end of the vehicle and at least front and rear pairs of ground engaging wheels with one wheel of each pair on each side of the vehicle. At least one pair of wheels is power driven. The operator's position is offset to one side of the pivotal mount for the boom. The operator's position may include a seat which can be moved between a first position on a longitudinal center line of the vehicle and a second position to one side of the vehicle center line.
Patent AU-2002211018-B2 (AU)
Title: Cellulosic particle for pharmaceutical preparation
Inventor: HIRANO YUUJI
IPC: C08L1/02
Filed: 2001-11-06
Granted: 2004-08-05
Abstract: Cellulose particles for pharmaceutical, which contains microcrystalline cellulose having an average degree of polymerization of from 60 to 350 in an amount of not less than 10%, and which have a tapped bulk density of from 0.60 to 0.95 g/ml, an aspect ratio of not less than 0.7, a shape factor of from 1.10 to 1.50, and an average particle size of from 10 to 400  mu m.
Patent AU-2002223162-B2 (AU)
Title: Fatty acid analogues for the treatment of inflammatory and autoimmune disorders
Inventor: AUKRUST PAL
IPC: A61P31/10
Filed: 2001-11-27
Granted: 2006-11-30
Abstract: The present invention relates to fatty acid analogues of the general formula R1-[xi-CH2]n—COOR2 and in particular to a method of treating inflammatory disorder selected from the group consisting of rheumatoid arthritis, systemic vasculitis, systemic lupus erythematosus, systemic sclerosis, dermatomyositis, and polymyositis; comprising administering to a mammal in need thereof, an effective amount of tetradecylthioaceticacid or tetradecylselenoacetic acid; or a pharmaceutically acceptable salt thereof.
Patent AU-2002301683-B2 (AU)
Title: Phosphonic acid derivative treatment of metallic flakes
Inventor: SOUERWINE ROBERT E
IPC: C09D7/12
Filed: 2002-10-29
Granted: 2008-08-14
Abstract: Metal pigment particles are treated with a product resulting from the reaction between an organic phosphonic acid with an amine having at least one organic group containing at least six carbon atoms to inhibit their reactivity to water. The treated metal particles can be used in coating and ink compositions. Additionally, the treated metal particles can be used to formulate pastes and dispersions that are provided to a coatings manufacturer.
Patent AU-2002319453-B2 (AU)
Title: Apparatus and method for analysing a biological sample in response to microwave radiation
Inventor: ELLISON BRIAN NORMAN
IPC: G01N21/27
Filed: 2002-07-19
Granted: 2008-04-24
Abstract: Apparatus for exposing a chemical, biological or biochemical sample to radiation comprises a sample passage (42) for conveying a sample in liquid phase along a sample path and at least one generator or source (48) for generating electromagnetic radiation and directing it at said sample path. The apparatus further includes at least one detector (46) for detecting at least one of reflected emitted and transmitted radiation from at least one point along said sample path and a controller (58) for controlling at least one of said generator or source and said detector. There is also a device (514) for dividing the liquid sample into two or more segments which pass in sequence along said sample path (804) in use.
Patent AU-2002340959-B2 (AU)
Title: Method for producing 1-olefins using palladium carbene compounds
Inventor: ROTTGER DIRK
IPC: C07B47/00
Filed: 2002-10-01
Granted: 2007-08-02
Abstract: Production of  alpha -olefins with 8-16 carbon atoms by telomerizing a conjugated diene with a nucleophile in the presence of a palladium catalyst, hydrogenating the telomer and cleaving the product, comprises using a carbene complex catalyst as the palladium catalyst.  An Independent claim is also included for polyolefins produced by copolymerizing olefins with  alpha -olefins produced as above.
Patent AU-2003290915-B2 (AU)
Title: Method for manufacturing resin-impregnated endless belt and a belt for papermaking machines and similar industrial applications
Inventor: PAQUIN MAURICE
IPC: D21F3/02
Filed: 2003-11-13
Granted: 2008-11-20
Abstract: A method for manufacturing resin-impregnated endless belt structures and belt structures designed for use on a long nip press on a papermaking machine and for other papermaking and paper processing applications, requires the application of a sacrificial material onto a base substrate in a predetermined pattern in droplets having an average diameter of 10mu (10 microns) or more. Polymeric resin material is then deposited on the base substrate to cover all areas except those on which the sacrificial material has been previously applied. The polymeric resin material is then set by means appropriate to its composition, and the sacrificial material removed. Optionally, the polymeric resin material may then be abraded to provide the belt with a uniform thickness, and a smooth, macroscopically monoplanar surface.
Patent AU-2003291433-B2 (AU)
Title: Compositions and methods for cancer diagnosis and therapy
Inventor: CROCE CARLO M
IPC: C12Q1/68
Filed: 2003-11-12
Granted: 2008-05-22
Abstract: The miR15 and miR16 micro RNA genes are located at 13q14 within a 30 kb region of loss characteristic of cells from certain cancers, such as cells from chronic lymphocytic leukemia or prostate cancer. Chronic lymphocytic leukemia or prostate cancer can be diagnosed by detecting a reduction in miR15 or miR16 gene copy number, by determining miR15 or miR16 gene mutational status, or by detecting a reduction in the RNA transcribed from these genes. The miR15 or miR16 gene products can inhibit the neoplastic or tumorigenic growth of cancers such as chronic lymphocytic leukemia or prostate cancer cells when administered to subjects suffering from these diseases.
Patent AU-2005216588-B2 (AU)
Title: Method for the determination of hemodynamic parameters
Inventor: WELLNHOFER ERNST
IPC: A61B5/0215
Filed: 2005-02-16
Granted: 2010-06-17
Abstract: A method for determining haemodynamic parameters from patient pressure signals includes receiving patient pressure signals from a measurement receiver to which vessel pressures measured in the body of a patient are supplied, selecting and determining a patient pressure signal as reference pressure signal from the patient pressure signals sent from the measurement receiver, dividing the patient pressure signals and reference pressure signal into segments, and examining these segments for artifacts with methods in the time range by using the first derivative with respect to time of the pressure signals wherein artifact afflicted segments are discarded. The method further includes determining the start and end of a heart beat by the reference pressure signal and using the non-discarded segments of the patient pressure signals for calculating haemodynamic parameters.
Patent AU-2005304245-B2 (AU)
Title: Flat self-opening closure for composite packagings or for container nozzles or bottle necks to be closed by film material
Inventor: GREGOR OTT
IPC: B65D5/74
Filed: 2005-11-04
Granted: 2011-10-13
Abstract: The self-opening closure comprises a pouring spout (3), a screw cap (1) and a self-opening cylinder (2) which is disposed inside the pouring spout (3) and can be set rotating by the screw cap (1). The self-opening cylinder (2), on its lower rim and protruding therefrom, comprises three combined piercing and cutting elements (5, 6, 7). These elements are disposed on two opposite positions on the periphery and in a position between the two. The interior of the self-opening cylinder (2) is provided with three nail-type integrally molded elements (9, 10, 11) which are evenly distributed across the periphery and extend towards the center of the cylinder and have a nail shank (12) and a nail head (13). The nail shank (12) and the bottom side of the nail head of every integrally molded element acts as a guide for one of the three cylinder wall segments that are located on the interior of the cap concentrically to the axis of rotation of the cap. The screw cap (1), on is lower rim (25), is connected to a flat retaining element (21) via at least two material bridges (22, 23, 24) that extend non-radially in relation thereto and that are configured as predetermined breaking points. Said retaining element can engage with the flange (20) of the pouring spout (3) in a horizontal position by means of pins.
Patent AU-2005317128-B2 (AU)
Title: Flexible surgical needle device
Inventor: IRVING WAXMAN
IPC: A61B10/00
Filed: 2005-12-14
Granted: 2011-08-18
Abstract: Medical devices (11, 51), surgical needle device systems (10), and methods (100) for utilizing an elongate surgical needle (54) that may be used through an endoscope working channel or through an external accessory channel device used with an endoscope are provided. The needle (54) has a proximal end (90) and a flexible distal end (91), an opening (92) at or near the proximal end (90) and an opening (93) at or near the distal end (91), the openings (92, 93) defining a channel (83). The surgical needle distal end (91) comprises a tissue engaging section (94) and an intermediate section (95) being operatively coupled in an axial direction. The tissue engaging section (94) and intermediate section (95) have different flexibility such that the tissue engaging section has greater flexibility than the intermediate section. Optionally, the needle distal end (91) has a preformed bend (97) at or near the tissue engaging section (94), the preformed bend (97) capable of being constrained to a substantially linear configuration and capable of returning to the preformed configuration when unconstrained.
Patent AU-2006246298-B2 (AU)
Title: An improved process for heap leaching of nickeliferous oxidic ores
Inventor: HOUYUAN LIU
IPC: C22B3/06
Filed: 2006-05-11
Granted: 2011-09-22
Abstract: A process for the recovery of nickel and cobalt from a nickeliferous oxidic ore by heap leaching, the process including the steps of: a) forming the nickeliferous oxidic ore into one or more heaps; b) leaching the ore heap with a leach solution in a leach step wherein the leach solution includes an acid supplemented hypersaline water as the lixiviant, the hypersaline water having a total dissolved solids concentration greater than 30 g/l; and c) recovering the nickel and cobalt from the resultant heap leachate.
Patent AU-2006257543-B2 (AU)
Title: Method for preparing 1,3-propanediol and 2,3-tuanediol by the coarse starch material
Inventor: LIU DEHUA
IPC: C12P7/18
Filed: 2006-06-13
Granted: 2010-12-09
Abstract: The invention discloses a method for producing 1,3-propanediol and 2,3-butanediol from raw starch materials, including the following steps: 1)  Candida krusei  or  Hansenula Arabitolgens Fang  are inoculated into a fermentation medium with the saccharifying liquid of the raw starches as a carbon source; the yeast cells are cultured on an aerobic condition until glucose-consuming-rate is significantly reduced, and then fermented anaerobically to a glucose concentration from 5 to 10 g/L; the fermentation broth is collected and filtered to remove the yeast cells in the broth, and the resultant filtrate is glycerin fermentation broth; 2)  Klebsiella, Clostridium butyricum,  or  Clostridium pasteurianum  are inoculated into a fermentation medium in which the glycerin fermentation broth obtained from step 1) serves as a carbon source; the bacteria are fermented anaerobically for 30-32 hours, and then fermented aerobically when the production rate of 1,3-propanediol decreased obviously, and the fermentation was stopped when the concentration of glycerin is reduced to a level below 10g/L, and finally 1,3-propanediol and 2,3-butanediol are obtained. The method of the present invention can effectively reduce production cost and increase productivity.
Patent AU-2006297390-B2 (AU)
Title: MIMO beamforming-based single carrier frequency division multiple access system
Inventor: PAN JUNG-LIN
IPC: H04L27/26
Filed: 2006-09-25
Granted: 2009-09-03
Abstract: A multiple-input multiple-output (MIMO) beamforming-based single carrier frequency division multiple access (SC-FDMA) system is disclosed. At the transmitter, a fast Fourier transform (FFT) is performed on transmission data to generate frequency domain data. The frequency domain transmit data is mapped to assigned subcarriers. An inverse fast Fourier transform (IFFT) is performed on the transmit data mapped to the assigned subcarriers to generate time domain transmit data. The time domain transmit data is transmitted via antennas. At a receiver, an FFT is performed on the received data to generate frequency domain received data. Subcarrier demapping is performed to extract data mapped on the assigned subcarriers. A channel estimator generates a channel matrix which is decomposed into U, D and V H  matrices. A channel distortion and interference between transmit and receive antennas are equalized based on the decomposed channel matrices to the extracted frequency domain received data.
Patent AU-2006316610-B2 (AU)
Title: Delta-9 elongases and their use in making polyunsaturated fatty acids
Inventor: DAMUDE HOWARD GLENN
IPC: C12N9/10
Filed: 2006-11-16
Granted: 2012-06-14
Abstract: The present invention relates to Δ9 elongases, which have the ability to convert linoleic acid [18:2, LA] to eicosadienoic acid [20:2, EDA]. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ9 elongase along with methods of making long-chain polyunsaturated fatty acids (PUFAs) using these Δ9 elongases in plants and oleaginous yeast are disclosed.
Patent AU-2006334522-B2 (AU)
Title: Hip distraction
Inventor: DALEY II EDWARD J
IPC: A61G13/00
Filed: 2006-11-21
Granted: 2012-12-13
Abstract: An apparatus includes a distractor assembly adapted to couple to a leg and capable of providing a distraction load on the leg in both supine and lateral positions of the leg. The assembly is coupled to a surgical table by a ball joint or a universal joint. A method includes coupling a leg to a distractor assembly, positioning the leg in one of a distraction mode and a femoral acetabular impingement mode, and repositioning the leg in the other of the modes without the need for accessing a draped pelvis/thigh region.
Patent AU-2007237285-B2 (AU)
Title: Four-stage high efficiency furnace
Inventor: THOMPSON KEVIN D
IPC: F24H3/02
Filed: 2007-11-30
Granted: 2011-11-24
Abstract: FOUR-STAGE HIGH EFFICIENCY FURNACE A four-stage furnace includes a gas flow control assembly operable 5 to provide gas to the furnace at one of four firing rates. The furnace also includes a heat exchanger and an inducer blower for establishing a flow of combustion gas that generates a differential pressure across the heat exchanger. A furnace controller controls the rate at which the gas flow control assembly provides gas to the furnace and controls the inducer 10 blower to establish one of four combustion gas flows that corresponds to one of the four firing rates. 28 3_0 46
Patent AU-2007252836-B2 (AU)
Title: Method and device for enhanced blood flow
Inventor: NACHUM ZVI
IPC: A61N1/00
Filed: 2007-05-17
Granted: 2012-05-31
Abstract: A non-invasive method and device for promoting a localized change in a flow of blood through a limb segment by a series of electrically stimulated contractions of muscle tissue, the method including: (a) providing a device including: (i) at least a first electrode, a second electrode, and a third electrode, each of the electrodes for operatively contacting the limb segment of the body; (ii) a signal generator, operatively connected to each electrode, for producing a series of electrical impulses to the limb segment via the electrodes, and (iii) a control unit, associated with the signal generator, for controlling the signal generator so as to produce the series of electrical stimulation impulses; (b) positioning the plurality of electrodes on the limb segment; (c) applying electrical impulses to induce a substantially radial contraction of a first portion of the muscular tissue in the limb segment; (d) applying electrical impulses to induce a substantially longitudinal contraction of a second portion of the muscular tissue in the limb segment, such that the muscular tissue acts upon the blood vessel to produce the localized change in the flow of blood.
Patent AU-2007267506-B2 (AU)
Title: Addressing device and method, and converter
Inventor: KROPP WOLFGANG
IPC: G06F13/38
Filed: 2007-05-16
Granted: 2011-03-24
Abstract: The device (1) has a switching logic shifting the device from standard to extended addressing modes. The device implements a slave (3) e.g. asynchronous (AS)-interface slave and field bus slave, with a standard address operation in the standard mode. The device implements a set of slaves with an address operation, which is different from the standard address operation, in the extended mode, where different data types are exchanged between a master and the slaves over data exchange mechanisms. The master assigns addresses to the slaves in the standard mode. An independent claim is also included for a method for addressing a device which is provided as bus nodes.
Patent AU-2007287749-B2 (AU)
Title: Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders
Inventor: SCHLEMMER KARL-HEINZ
IPC: C07D413/14
Filed: 2007-08-23
Granted: 2013-09-12
Abstract: The present application relates to prodrug derivatives of 5-chloro-
Patent AU-2007327373-B2 (AU)
Title: Urine collection device
Inventor: FORTE VINCENT JOHN CHARLES
IPC: A61B10/00
Filed: 2007-09-25
Granted: 2012-08-23
Abstract: A urine collection device comprises a collection means (102) to collect urine voided by a user, first and second outlet means (103, 108) adapted to allow urine collected by the collection means (102) to drain from the device and a transfer passage (111) adapted to transfer urine collected by the collection means (102) to a receptacle (110). The first outlet means (103) includes a flow rate variation device (106) so constructed and arranged that an initial drain flow rate through the variation device is greater than a second drain flow rate through the variation device; and the second outlet means (108) comprises an overflow outlet means (118) adapted to allow urine collected by the collection means (102) to drain from the urine collection device at a third drain flow rate equal to or higher than the initial drain flow rate through the variation device.
Patent AU-2007332142-B2 (AU)
Title: Heating and cooling system
Inventor: SCHMIDT TILO
IPC: F24S90/00
Filed: 2007-12-11
Granted: 2013-01-24
Abstract: An integrated heating and cooling system for a living space of a building is disclosed. The system connects together (a) a solar-based heating and cooling system and (b) heating and cooling systems that rely directly or indirectly on fossil fuels that are conventionally used in buildings. The system operates the solar-based heating and cooling system preferentially to heat or cool the living space. Therefore, the system minimises the use of fossil fuels to heat and cool the living space.
Patent AU-2007354803-B2 (AU)
Title: Method of and device for attracting aquatic life forms using an electromagnetic field generation
Inventor: SAUE VIDAR
IPC: A01K85/01
Filed: 2007-07-31
Granted: 2012-04-05
Abstract: A device (100) for simulating and/or attracting aquatic life forms is disclosed. The device (100) includes an electromagnetic module (200) for simultaneously generating alternating or pulsed electromagnetic fields and a pulsed light output from a light emitting diode (101). The electromagnetic module (200) includes a dry battery (105) that is activated when exposed electrodes (106,107) of the dry battery (105) are placed in contact with a common electrolyte, such as sea water. The electromagnetic module (200) includes a control circuit (103) with one or more application specific integrated circuit (901, 903) for converting an input voltage from the dry battery (105) to an operating voltage sufficient to power the light emitting diode (101). The device (100) can further include one or more removable jackets (109) that resemble aquatic life forms.
Patent AU-2008206575-B2 (AU)
Title: Compositions and methods of reducing side effects and toxicity of methotrexate when given as orotate derivatives
Inventor: KARMALI RASHIDA A
IPC: A61K31/525
Filed: 2008-01-18
Granted: 2013-02-21
Abstract: This invention is in the field of chemical restructuring of antimetabolite agents known to have poor oral bioavailability and to cause tissue toxicity as a side effect, by producing their orotate derivatives. More particularly, it concerns orotate derivatives of the methotrexate and trimetrexate, that are found to improve the oral bioavailability and clearance compared with their respective forms- methotrexate and trimetrexate, currently in use. The present invention provides methotrexate orotate having the formula: