baber/WOPTO huggingface dataset:
Patent DE-69333886-T2 (DE)
Inventor: LEIDEN JEFFREY M
IPC: A61K35/76
Filed: 1993-11-16
Granted: 2006-07-27
Abstract: The present invention relates to the use of adenovirus-mediated gene transfer to regulate function in cardiac and vascular smooth muscle cells. A recombinant adenovirus comprising a DNA sequence that codes for a gene product is delivered to a cardiac or vascular smooth muscle cell and the cell is maintained until that gene product is expressed. Delivery is direct injection into a muscle cell or infusing a pharmaceutical composition containing an adenovirus vector construct intravascularly.
Patent DE-69411382-T2 (DE)
Inventor: WADDINGTON SIMON DOMINIC
IPC: C08L101/16
Filed: 1994-01-12
Granted: 1999-02-04
Abstract: PCT No. PCT/GB94/00056 Sec. 371 Date Jul. 13, 1995 Sec. 102(e) Date Jul. 13, 1995 PCT Filed Jan. 12, 1994 PCT Pub. No. WO94/16000 PCT Pub. Date Jul. 21, 1994.A supported or cast film of a polyhydroxyalkanoate polymer, such as a polyhydroxybutyrate/valerate polymer, can be prepared by applying a layer of molten polymer to a cool (typically 4 DEG  to 20 DEG  C.) surface not substantially above the glass transition temperature of the polymer, so as to form a solid, glassy film with a high density of nucleation sites; subsequently the temperature of the film so formed is raised, for example to 40 DEG  C. or more, towards the optimum temperature for growth of the polymer's spherulites effectively separating the film formation/nucleation step from the crystallisation step (growth of spherulites around the nucleation sites). Smaller crystallites are formed, and the film has improved barrier properties.
Patent DE-69431542-T2 (DE)
Inventor: ALEX PATRICK
IPC: C08L71/02
Filed: 1994-04-13
Granted: 2003-03-20
Abstract: Composition based on a thermoplastic elastomer including polyether blocks in which the content of ethanol-extractable matter is lower than a value which is sufficient to prevent exudation.
Patent DE-69435039-T2 (DE)
Inventor: OLEFSKY JERROLD
IPC: A61P43/00
Filed: 1994-09-14
Granted: 2008-08-14
Abstract: Treatment of impaired glucose tolerance, in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus comprises admin. of :(a)eg. a cpd. of formulae (I) or (II)(or a salt of these);(b) a cpd. of formula (IV) (or a cationic salt of (IV), or an acid addn. salt of (IV) when it contains a basic N atom);(c) a cpd. of formula (V) (or a cationic salt of (V), or an acid addn. salt of (V) when A or B is N);or (d) eg. a cpd. of formulae (VII) (or a tautomer, salt or solvate): R1, R2 = H or 1-5C alkyl; R3 = H, 1-6C aliphatic acyl,etc.;R4, R5 = H, 1-5C alkyl or 1-5C alkoxy; or R4+R5 = 1-4C alkylenedioxy; m = 1- 3; W = CH2 or CO etc.;Y, Z = O or NH; R11 = opt. substd. alkyl, alkoxy,etc.;L1, L2 = H or lower alkyl; or L1+L2 = alkylene;V = CH=CH, N=CH, CH=N or S; Za = H, 1-7C alkyl, 3-7C cycloalkyl,etc.;Z1 = H or 1-3C alkyl;q = 1- 3; A, B = CH or N, provided that they are not both N; X1 = S, O, SO2,etc.; s = 0-1; Y1 = CHR20 or R21; Z2 = CHR22, CH2CH2, CH=CH,etc.;R1y is not given; X2, X3 = H, Me, CF3, phenyl,etc. A2 = alkyl, opt. substd. aryl or opt. substd. aralkyl; A3 = a benzene ring with \~3 opt. substits.;R24 = H, alkyl, acyl, or opt. substd. aryl or aralkyl; or A2+R24 = 2-3C polymethylene (opt. substd. by alkyl or aryl, adjacent substits. together with the methylene carbon atoms opt. forming an opt. substd. phenylene gp.); R25, R26 = H; or R25+R26 = a bond; X4 = O or S; n = 2-6.
Patent DE-69502276-T2 (DE)
Inventor: DRILLER HUBERT
IPC: H05K13/08
Filed: 1995-02-23
Granted: 1998-08-20
Abstract: Method and apparatus for setting the contact elements (test pins) of a printed circuit board test device, which are accommodated in one or two test adapters, to the contact points, provided on one or both sides, of a printed circuit board (series) to be tested, wherein said printed circuit board (series) comprises various subsets of contact points and suitable alignment means with respect to the adapters, in particular two reference holes or reference edges. The new and inventive feature is considered to consist in the fact that at least one subset of the contact elements (S) of one or both adapters (BF, BA; TF, TA), independently of at least one further subset of the contact elements (H), and the alignment means (T) of one or both adapters are set relative to one another.
Patent DE-69527513-T2 (DE)
Inventor: FOLEY F
IPC: H04N9/64
Filed: 1995-03-28
Granted: 2003-02-27
Abstract: The invention pertains to a method and apparatus for performing dynamic purity correction to insure that color purity is maintained across the face of a color monitor. The monitor displays a plurality of pixels, each having a particular luminescence value. Each luminescence value has several color components (E.g. red (R), green (G) and blue (B)). A grid of luminance measurements is made across the face of the monitor for each color component. From these luminance value grids, smoothly varying correction values are computed for each color component of each pixel by the interpolation of cubic splines, such as a Catmull-Rom spline. Incoming digital video signals are multiplied by corresponding correction values to insure color accuracy of the monitor. In a preferred embodiment, the calculation of correction values is repeatedly performed in real time (at the display dot clock rate) in a single monolithic RAMDAC integrated circuit to increase speed, improve fidelity, and minimize use of memory space.
Patent DE-69533427-T2 (DE)
Inventor: DUNTON RONALD K
IPC: A61K8/92
Filed: 1995-12-27
Granted: 2005-08-18
Abstract: The present invention discloses applicators containing cationic surface active agents, hydrophobic barrier-forming materials and antimicrobial compounds which form, upon application to dental surfaces, a protective and bacteria-inhibiting film.
Patent DE-69534530-T2 (DE)
Inventor: LEUNG SHUI-ON
IPC: A61K47/48
Filed: 1995-08-11
Granted: 2006-07-06
Abstract: A chimeric LL2 monoclonal antibody is described in which the complementarity determining regions (CDRs) of the light and heavy chains of the murine LL2 anti-B-lymphoma, anti-leukemia cell monoclonal antibody has been recombinantly joined to the human kappa and IgG<SUB>1 </SUB>constant region domains, respectively, which retains the immunospecificity and B-cell lymphoma and leukemia cell internalization capacity of the parental murine LL2 monoclonal antibody, and which has the potential of exhibiting reduced human anti-mouse antibody production activity. A humanized LL2 monoclonal antibody is described in which the CDRs of the light and heavy chains have been recombinantly joined to a framework sequence of human light and heavy chains variable regions, respectively, and subsequently linked to human kappa and IgG<SUB>1 </SUB>constant region domains, respectively, which retains the immunospecificity and B-lymphoma and leukemia cell internalization capacities of the parental murine and chimeric LL2 monoclonal antibodies, and which has the potential for exhibiting reduced human anti-mouse antibody production activity. Vectors for producing recombinant chimeric and humanized chimeric monoclonal antibodies are provided. Isolated DNAs encoding the amino acid sequences of the LL2 variable light and heavy chain and CDR framework regions are described. Conjugates of chimeric and humanized chimeric LL2 antibodies with cytotoxic agents or labels find use in therapy and diagnosis of B-cell lymphomas and leukemias.
Patent DE-69535515-T2 (DE)
Inventor: HALE NATHAN S
IPC: C09D11/00
Filed: 1995-09-01
Granted: 2008-02-21
Abstract: An image is printed on a medium by means of a computer-driven printer (6) using an ink composition comprising heat-activated dye solids, without activating the dye solids during the process of printing onto the medium. The image is transferred from the medium to the object (8) on which the image is to permanently appear by applying heat and pressure to the medium to activate the dye and transfer the image to the object (8). The liquid form of the ink composition uses a liquid carrier and an emulsifying enforcing agent which has an affinity for the dye. The emulsifying enforcing agent shields the heat-activated dye both prior to, and during, the printing process.
Patent DE-69602592-T2 (DE)
Inventor: NAUD GEORGES
IPC: A01B3/46
Filed: 1996-02-27
Granted: 1999-11-18
Abstract: A plough consisting of a frame made of two portions (3, 5) interconnected above the supporting carriage (2) along a transverse axis (6) that is horizontal when the plough is in its use position, said portions being further held in alignment by spring buffers (7). Said plough comprises, adjacent to the transverse axis (6), a pivot member (10) and a runner (11) for converting the connection into a kind of universal joint whereby the rear portion (5) is movable along the central plane of the frame (1), in particular during transport.
Patent DE-69615472-T2 (DE)
Inventor: NEUERBURG HORST
IPC: A01D57/30
Filed: 1996-07-01
Granted: 2002-05-23
Abstract: The reaper which is connected to a tractor has a cutting mechanism (3) comprising dynamic cutting elements (7,7',7")with cutting tools (6). A swathing system (40) displaces the cut products laterally towards the median plane (13) of the cutting mechanism before they are placed on the ground. The swathing system comprises a cut product guide element (42',42") situated near one of the lateral ends (10',10") of the cutting mechanism. The guide element comprises two rotors (45,46) located transverse to the direction of advance and the rotational axis (71,72). These guides are directed upwards during working. The rotors are suspended from a carrying structure (33) connected to the cutting mechanism and rotated by a drive mechanism (73',73"). The lower end (59,60) of a rotor extends as far as the cutting plane (61) defined by the cutting tools of the corresponding cutting elements.
Patent DE-69617744-T2 (DE)
Inventor: DUFFET-SMITH JAMES
IPC: H04W64/00
Filed: 1996-09-19
Granted: 2002-05-23
Abstract: The invention relates to a position determining system, for receiving digital telephone signals transmitted by a number of transmission sources BTS. In particular there is described a method of estimating the offset in time of receipt of a broadcast signal received at two locations (CBU,CRU), where the signal received at the one location (CRU) may have been subject to corruption by multipath effects. To overcome this problem, the signals received at the one location are auto-correlated and the signals received at the other location are auto-correlated. The signals received at the two locations are cross-correlated and a template comprising that portion of the auto-correlation of the signals received at the other location corresponding to the negative time axis, and that portion of the auto-correlation of the signals received at the one location corresponding to the positive time axis is constructed. The offset at which the template best fits the measured cross-correlation of the signals received at the two locations is measured as an estimate of the time offset between the signals received at the two locations. <IMAGE>
Patent DE-69622413-T2 (DE)
Inventor: FUCHSNE TOLNAY JUDIT
IPC: A63H29/08
Filed: 1996-08-30
Granted: 2003-03-06
Abstract: PCT No. PCT/HU96/00047 Sec. 371 Date Feb. 2, 1998 Sec. 102(e) Date Feb. 2, 1998 PCT Filed Aug. 30, 1996 PCT Pub. No. WO97/07866 PCT Pub. Date Mar. 6, 1997A building plaything comprising building elements, connected in a known way and produced in module size or in any multiple thereof, for creating rolling tracks, upon the building elements a rolling groove is shaped and directrix of the rolling groove is straight or arched or slanting, and the plaything comprising connecting elements to be joined to the building elements in the known way, and the building elements are shaped as at least one of the following elements: as straight element, as slanting element, as arched element, the plaything furthermore comprising a rolling element wherein the rolling groove is shaped with slanting sides having an obtuse angle to one another, further, for the purpose that the slanting element can be placed also at right angle to any of the building elements gradient of the slanting side of the rolling groove of the building elements is the same as the gradient of the directrix of the slanting element.
Patent DE-69624904-T2 (DE)
Inventor: KURIHARA KATSUYUKI
IPC: B01D46/02
Filed: 1996-08-06
Granted: 2003-04-10
Abstract: In a method for treating a combustion exhaust gas from a waste burning facility, the exhaust gas has its temperature lowered to 180 - 230 DEG C, in a temperature lowering unit, is freed of dust in a dry dust collector, passed through a dioxin and NOx removing unit using a vanadium oxide-based catalyst and, thereafter, the exhaust gas at 180 - 230 DEG C is further passed through a heat exchanger to effect heat recovery. The vanadium oxide-based catalyst is a vanadium oxide alone or the combination thereof either with an oxide of at least one element selected from the group consisting of molybdenum, tin, yttrium, boron and lead or with gold. In addition, a tungsten oxide may be used. These catalysts are preferably carried on titania for use. The method and an apparatus for implementing it require a simple system configuration and yet assure high thermal efficiency while achieving efficient removal of dioxins and nitrogen oxides. <IMAGE>
Patent DE-69625934-T2 (DE)
Inventor: OESTLUND AKE
IPC: C22C29/08
Filed: 1996-11-29
Granted: 2003-11-13
Abstract: A coated milling insert particularly useful for milling in low and medium alloyed steels with or without raw surface zones during wet or dry conditions. The insert is characterized by a WC-Co cemented carbide with a low content of cubic carbides and a highly W alloyed binder phase and a coating including an inner layer of TiC<SUB>x</SUB>N<SUB>y</SUB>O<SUB>z </SUB>with columnar grains, a layer of kappa-Al<SUB>2</SUB>O<SUB>3 </SUB>and, preferably, a top layer of TiN. The layers are deposited by using CVD methods.
Patent DE-69628640-T2 (DE)
Inventor: WONG SUI-MING
IPC: A61K9/16
Filed: 1996-02-22
Granted: 2004-05-19
Abstract: There is disclosed a composition containing nanoparticles having a surface modifier wherein the surface modifier is a block copolymer containing one or more polyoxyethylene blocks and one or more polyoxy(higher alkylene) blocks wherein at least some of the blocks are linked together by a linking group characterized in that the linking group is an oxymethylene group.
Patent DE-69631659-T2 (DE)
Inventor: RAZAVI ABBAS
IPC: C07F17/00
Filed: 1996-10-09
Granted: 2004-12-23
Abstract: A process for the preparation of a meso/racemic-Äbis(indenyl)ethaneÜ zirconium dichloride compound comprising (a) reacting zirconium tetrachloride with the solid reaction product of the bis(indenyl)ethane ligand with an alkyllithium in a solvent as reaction medium and (b) recovering a solid mixture of lithium chloride and meso/racemic composition of Äbis(indenyl)ethaneÜzirconium dichloride, characterized in that the solvent used as reaction medium in reaction (a) is an ether, pentane or a mixture thereof.
Patent DE-69634083-T2 (DE)
Inventor: BALL E
IPC: B65D39/10
Filed: 1996-06-05
Granted: 2006-03-02
Abstract: A suction container usable to suction fluids from the surgical field in an operating room environment. The container has a rigid cover overlying a flexible body portion attached thereto, the cover including a pour spout having a tubular body portion, a segmented thread disposed on an inner wall as a tubular body, the thread having a plurality of spaced segments, each segment defining a ramp and a stop. A locking cap is provided for mounting on the pour spout, the locking cap having a complementary tubular body for insertion into the pour spout, with complementary spaced ramped locking elements disposed on an outer surface of the tubular body for engaging the thread segments in locking the cap on the pour spout in fluid-tight engagement.
Patent DE-69636208-T2 (DE)
Inventor: KINDT-LARSEN TURE
IPC: B32B1/02
Filed: 1996-09-27
Granted: 2006-12-14
Abstract: A cover-forming laminated clear plastic film packaging material for at least one container, such as the base member of a blister package which is adapted to contain a hydrophilic contact lens in a sterile aqueous solution. More specifically, disclosed is a transparent or translucent laminated multi-layered plastic film material constituting a covering label for the container, incorporating a silicon oxide barrier layer. The laminate may be imprinted over a surface extent thereof with a specific pattern of indicia and legends.
Patent DE-69701269-T2 (DE)
Inventor: DHARANIPRAGADA RAMALINGA
IPC: A61P1/00
Filed: 1997-05-13
Granted: 2000-09-14
Abstract: This invention pertains to cyclic polypeptides having gastrointestinal motor stimulating activity which may be represented by formula (1): <CHEM> including optically active isomeric forms and the pharmaceutically acceptable acid addition salts thereof, wherein groups A and D are linked to from a cyclic structure; and R1 is lower alkyl; R2 is hydrogen or lower alkyl; R3 is hydrogen or lower alkyl; R4 is phenyl or substituted phenyl, wherein the phenyl group may be substituted with one or more substituents selected from the group consisting of halogen, hydroxy, and lower alkoxy; R5 is -OH or -NH2; A is selected from the group consisting of L-glutamic acid, L-aspartic acid, L-lysine, L-ornithine, and L-2,4-diaminobutyric acid; B is L-alanine or L-glutamine; C is L-arginine or D-arginine; D is selected from the group consisting of L-lysine, L-ornithine, L-2,4-diaminobutyric acid, L-glutamic acid, and L-aspartic acid; E is a direct bond between group D and group R5 or is L-lysine or D-lysine; m is 0 or 1; the symbol * represents an asymmetric carbon atom which may be in the D or L configuration, with the proviso that: (a) when A is L-glutamic acid or L-aspartic acid, D is L-lysine, L-ornithine, or L-2,4-diaminobutyric acid; and (b) when A is L-lysine, L-ornithine, or L-2,4-diaminobutyric acid, D is L-glutamic acid or L-aspartic acid. This invention also pertains to methods for using the novel cyclic polypeptides.
Patent DE-69717091-T2 (DE)
Inventor: MOMOSE YU
IPC: C07D413/12
Filed: 1997-04-02
Granted: 2003-07-31
Abstract: A novel compound of the formula:wherein R1 is a halogen atom, an optionally substituted heterocyclic, hydroxy, thiol or amino group; A is an optionally substituted acyl group, an optionally substituted heterocyclic group, an optionally substituted hydroxy group, or an optionally esterified or amidated carboxy group; B is an optionally substituted aromatic group; Y is a divalent aliphatic hydrocarbon group, or a salt thereof, which have an excellent insulin secertion-promoting and blood sugar-depressing effect, and useful in agents for diabetes.
Patent DE-69717474-T2 (DE)
Inventor: KOCHANNY MONICA
IPC: A61K31/497
Filed: 1997-09-11
Granted: 2003-06-26
Abstract: This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Patent DE-69720296-T2 (DE)
Inventor: LAMOREAUX BEN
IPC: E01B25/18
Filed: 1997-12-05
Granted: 2004-04-01
Abstract: An improved cableway system for providing a track over which a vehicle traverses is disclosed. The improved system includes a catenary cable system (16) and a pair of track cable systems (14). The track cable systems (14) are hung from the catenary cable system (16) and support tracks over which a vehicle (12) traverses. A plurality of hangers (27) is employed to suspend the track cable systems (14) from the catenary cable system (16). A plurality of pylons (17) support the catenary and track cable systems (14, 16). A pylon (17) includes a base pylon (21), a lower saddle (200), and an upper saddle (30). The lower saddle (200) is pivotally mounted to the base pylon (21) and supports the track cable systems (14). Preferred embodiments of the lower saddle (200) include apparatuses that dampen the application of loads to the pylon (17) by the vehicle (12) traversing the system. The upper saddle (30) is supported by the base pylon (21) and supports the catenary cable system (16) while providing for deflection of the catenary cable system (16) in response to forces applied to the cableway system. A preferred embodiment of the cableway system includes a force equalizing assembly (300) for joining the catenary cable system (16) to the track cable system (14) at points between support pylons (17) to equalize the tension in the cables among the various cables.
Patent DE-69722938-T2 (DE)
Inventor: CHIOU WALTER
IPC: G01T1/167
Filed: 1997-01-14
Granted: 2004-05-19
Abstract: A square anti-symmetric uniformly redundant array coded aperture includes transparent and opaque cells and exhibits a normal mask pattern at a first position and a complementary mask pattern when rotated to a second position rotationally offset by 90 DEG  from the first position. The coded aperture is utilized in a coded aperture imaging system for imaging a source of non-focusable radiation such as a gamma ray or x-ray emitting source. Such a coded aperture imaging system basically includes a square anti-symmetric uniformly redundant array coded aperture for receiving radiation emitted by a source and generating a first coded shadow therefrom at the first position, and a second coded shadow therefrom at the second position, a rotating platform and motor for rotating the coded aperture between the first and second position, a position sensitive detector situated with respect to the coded aperture to allow the first and second coded shadows to sequentially impinge on the detector, the detector respectively generating a first coded optical signal and a second coded optical signal in response thereto, an optical signal convertor responsive to the first and second coded optical signals and respectively generating a first coded electrical signal and a second coded electrical signal in response thereto and a signal processor responsive to the first and second coded electrical signals and decoding the coded electrical signals to generate an image signal which is representative of an image of the source of non-focusable radiation.
Patent DE-69729860-T2 (DE)
Inventor: DE SAEGER SARAH
IPC: G01N33/543
Filed: 1997-08-19
Granted: 2005-08-25
Abstract: The detection of mycotoxins is effected by flowing through a microporous membrane coated with immunoreagents and placed on a absorbent material. All reagents are dropped onto the membrane. Due to the contact between the membrane and the absorbent material, added reactants are drawn through the membrane into the absorbent material. The membrane is coated with anti-mouse antibodies. The following reactants are successively dropped onto the membrane wash solution, monoclonal anti-mycotoxin antibodies, wash solution, sample, enzyme labelled mycotoxin and wash solution. Finally, substrate solution is added to cause a colour development. This test is used for the detection of mycotoxins in food and feed.
Patent DE-69730296-T2 (DE)
Inventor: MONTANARI THIBAUT
IPC: C08L77/02
Filed: 1997-06-05
Granted: 2005-09-08
Abstract: The invention relates to a thermoplastic composition comprising at least one polymer (M) forming a matrix in which are dispersed nodules of (K), nodules of (K) entirely or partly encapsulated in at least one polymer (S) and nodules of (S) and such that the nodules of (K) entirely or partly encapsulated in (S) are smaller than the nodules of (S).