baber/WOPTO huggingface dataset:
Patent PT-1023069-E (PT)
Inventor: ANDERSSON SVEN BORJE
IPC: A61K31/05
Filed: 1998-09-15
Abstract: Polar lipid formulations of nicotine in liquid crystals and colloidal dispersions thereof and precursors or offspring thereof which when in contact with body fluid and/or by the influence of body temperature, are transformed to a liquid crystal or a mixture of liquid crystals, which functions as a controlled release matrix for nicotine suitable in e.g. smoking cessation and/or replacement therapies. Disclosed compositions of said liquid crystals or dispersions thereof, their precursors or offspring containing nicotine and anti-irritants or a local analgesic, or any combination of these reduce local irritation of nicotine and masks its taste. Applicable routes of administration and devices includes buccal, using chewing gum in which liquid crystals, dispersions thereof, or precursor or offspring thereof are formulated, buccal adhesives, gels and patches, using mucoadhesive liquid crystal, dispersions thereof or precursor thereof, and mouth spray using dispersion of said liquid crystals, their precursors or offspring, nasal spray and gel using said liquid crystals or their dispersions, their precursors or offspring, topical, using said liquid crystal or their precursors or offspring in adhesive patches and gels.
Patent PT-1082910-E (PT)
Inventor: DUPART PIERRE
IPC: A23L7/17
Filed: 1999-09-11
Abstract: Cooked-extruded-expanded savoury cereal having a porous texture and a specific weight of from 100 to 500 g/l, especially of from 150 to 350 g/l, which may be added alone or as part of a fix to eggs for preparing an egg based product, especially an omelet or scrambled eggs.
Patent PT-1115707-E (PT)
Inventor: BROWN DEARG SUTHERLAND
IPC: A61P19/08
Filed: 1999-09-21
Abstract: The invention concerns amide derivatives of formula (I)wherein R3 is (1-6C)alkyl or halogeno; m is 0-3, p is 0-2 and q is 0-4; each of R1 and R2 is a group such as hydroxy, halogeno, trifluoromethyl and cyano; R4 is a basic group such as amino, (1-6C)alkylamino, di-[(1-6C)alkyl]amino, di-[(1-6C)alkyl]amino-(1-6C)alkyl, di-[(1-6C)alkyl]amino-(2-6C)alkoxy, heteroaryl, heteroaryloxy, heteroaryl-(1-6C)alkoxy, heterocyclyl, heterocyclyloxy and heterocyclyl-(1-6C)alkoxy; and Q2 is a group such as heteroaryl, heteroaryloxy or heteroaryl-(1-6C)alkoxy which is optionally substituted; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
Patent SG-37991-G (SG)
Title: Dry-shaving apparatus
IPC: B26B19/16
Filed: 1991-05-14
Abstract: The invention relates to a dry-shaving apparatus comprising a housing (1), a holder (2) for a shear plate (3), which holder (2) is detachable from the housing (1), and a cutter (4) which is rotatable relative to the shear plate (3) and which comprises cutting elements (9) having cutting edges (10) at their radial ends. The housing (1) is provided with a guide wall (31,34) for the cutting elements (9), which guide wall (31,34) adjoins the shear plate (3).
Patent SG-60192-G (SG)
Title: Use of benzothiazepine derivatives in pharmaceutical compositions for improving constitution of lipids in blood
IPC: A61K31/55
Filed: 1992-06-05
Abstract: Disclosed are a pharmaceutical composition for improving the constitution of lipids in blood, which comprises as an active ingredient 2-(4-methoxyphenyl)-3-acetoxy-5-[2-(dimethylamino)ethyl]-8-chloro-2,3- dihydro-HY # 1,5-benzothiazepin-4(5H)-one or a pharmaceutically acceptable acid addition sait thereof and the use of the compound for preparing the pharmaceutical composition.
Patent SG-82086-G (SG)
Title: Laundry additive products
IPC: C11D17/04
Filed: 1986-10-10
Abstract: Laundry additive products comprising a solid laundry additive composition and a flexible, sheet-like apertured substrate carrying a water-releasable coating of the laundry additive composition. The substrate has an aperture density of from about 10 to 30 apertures per sq cm and the apertures have a width of from about 0.5 to 5mm and a length of from about 0.8 to 5mm. The product comprises areas of uncoated aperture and areas within the coating covers the apertures and extends between opposing surfaces of the substrate. The ratio of areas of uncoated to coated apertures is from about 15:1 to 1:3. The weight ratio of composition:substrate is at least 5:1. The additive products combine a high loading of composition together with excellent flexibility, product release, feel and storage characteristics.
Patent IE-860107-L (IE)
Title: Thiazolinediones
IPC: C07K14/57
Filed: 1986-01-14
Abstract: Thiazolidinedione derivatives of the formula: <CHEM> or pharmacologically acceptable salts thereof are novel compounds, which exhibit in mammals blood sugar- and lipid-lowering activity, and are of value as a therapeutic agent for diabetes and therapeutic agent for hyperlipemia.
[EP0193256A1]
Patent IE-840301-L (IE)
Title: Benzazocinone and benzazoninone derivatives
IPC: C07D225/00
Filed: 1984-02-09
Abstract: Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-benzazocin-2-one and benzazonin-2-one derivatives are disclosed as angiotensin converting enzyme inhibitors and antihypertensive agents. Synthesis of, pharmaceutical compositions and methods of treatment utilizing such compounds are included.
Patent IE-870334-L (IE)
Title: 2-substituted quinoline dioic acids
IPC: C07D215/18
Filed: 1987-02-09
Abstract: 2-Substd. quinoline cpds. of formula (II) and pharmaceutically acceptable salts are new where R1 = H, halogen, 1-8C alkyl, 2-8C alkenyl, 2-8C alkynyl, CF3, OR2, SR2, S(O)R2, SO2R2, NR2R3, CHO, COOR2, COR2, -C(OH)(R2)2, CN, NO2, opt. substd. phenyl, opt. substd. benzyl or opt. substd.phenyl, opt. substd. benzyl or opt. substd. phenethyl; R2 = H, 1-8C alkyl, 2-8C alkenyl, 2-8C alkynyl, CF3, opt. substd. phenyl, opt. substd. benzyl or opt. substd. phenethyl; R3 = H, halogen, NO2, CN, OR2, SR2, N(R2)2 or 1-8C alkyl; CR2R3 may be the radical of a naturally occurring amino acid, R4 = H, halogen, NO2, CN, OR2, SR2, N(R2)2, 1-8C alkyl or COR2, R5 = (CH2)s-C(R6)2-(CH2)s-R7, R6 = H or 1-4C alkyl; R7 = W-R8 or mono- or bicyclic heterocyclic gp. contg. 3-12 ring C and 1 or 2 N, O or S heteroatoms, each ring being 5- or 6-membered; R8 = max. 21C hydrocarbyl or acyl residue of an acyclic or monocyclic carboxylic acid contg. max. heteroatom in the ring; R9=OR10, SR10, or N(R10)2; R10 = H, 1-6C alkyl, -COR11, phenyl or benzyl, or N(R10)2 may form a 5- or 6-membered ring contg. up to 2 N,O or S heteroatoms; R11 = H, 1-8C alkyl, 2-8C alkenyl, 2-8C alknyl, CF3, phenyl, benzyl or phenethyl; R12 = R2 or halogen; m,m'= 0-8; n,n'= 0 or 1; p,p'= 0-8; m+n+p = 1-10; m'+n'+p'= 1-10; s = 0-3; Q1,Q2 = COOR2, tetrazole, COOR5, CONHSO2R11, CM, CON(R10)2, CHO, CH2OH, COCH2OH or NHSO2R11; or if Q1 or Q2 = COOH and R3 = OH, SH or NHR2, then Q1 or Q2 and R3 and the C atoms through which they are attached may form a heterocyclic ring with loss of water; W= O,S or NH; X'= O, S, SO2, NR2 or C(R2)2; X2, X3 = O, S, SO or SO2, Y = -CR2=CR2-, ethynylene, -C(R2)2-X1-, -X1-C(R2)2-, -C(R2)2-X'-C(R2)2-, -CO-, -NR2-CO-, -CO-SR2-, O, S, NR2 or cyclopropanedinyl of formula (a); Z1,Z2 = -CONR2-.
Patent IE-37376-L (IE)
Title: Dietary formulation
IPC: A23L1/30
Filed: 1973-03-06
Abstract: 1356370 Dietetic compositions A N HOWARD 6 March 1973 [6 March 1972] 10439/72 Heading A2B A dietary formulation for the treatment of obesity in man comprises:-(a) all the minerals required by man, (b) proteinaceous material consisting of:-(i) a mixture of monomeric L- amino acids and/or (ii) natural proteins, and/or (iii) natural proteins reinforced with at least one monomeric L-amino acid; and (c) digestible carbohydrate, such that the smallest amount of the formulation containing at least the minimum daily requirements of each of the minerals required by man also contains:- (A) at least 15gm of the proteinaceous material which must include at least the minimum daily requirements of all the essential L-amino acids required by man, and (B) 15-75 gm of the digestible carbohydrate; the total caloric value of the said smallest amount of formulation being in the range 160-600 Kcals. The composition should additionally contain at least the minimum daily requirement of vitamins and sufficient fat, oil, or other source of essential fatty acids to supply the minimum fatty acid requirements. The proteinaceous material may include egg albumen, or natural protein derived from milk. soya beans, peanuts, fish, or plasma, which may be reinforced with at least one monomeric amino acid to give the desired amino acid profile, or it may include a mixture of amino acids produced by hydrolysis of a protein by an acid or a proteolase with necessary adjustment of the amino acid profile. The formulation may additionally include bulking agents, for example cellulose, methyl cellulose, and acacia, tragacanth, guar, or xanthan gums. Also present may be emulsifiers and flavourings.
[GB1356370A]
Patent IE-850961-L (IE)
Title: Cephalosporins
IPC: C07D213/53
Filed: 1985-04-16
Abstract: Novel cephalosporin derivatives and salts thereof are disclosed. These compounds exhibit excellent antimicrobial activity against a wide variety of Gram-negative and Gram-positive bacteria and also have other excellent characteristics as a medicine such as stability and low toxicity. These compounds can be administered in a form of subcutaneous, intravenous or intramuscular injections.
[US4833242A]
Patent FI-843760-L (FI)
Inventor: BITZINGER RUDOLF
IPC: H04Q3/545
Filed: 1984-09-25
Abstract: Multiprocessor controller, especially a multiprocessor central control unit of a telephone switching unit, having a bus system (B:CMY) to which there are connected the processors (CP, IOC), which have a separate local memory (LMY) or no separate local memory (LMY), and which is allocated alternately to different processors of the group (e.g. CP1, CPx, IOC0). The multiprocessor controller has a main memory (CMY), which is connected to the bus system (B:CMY) and to which the processors (CP, IOC) can alternately have access in accordance with the allocations of the bus system (B:CMY) via the bus system (B:CMY), and via which processors (CP, IOC) can communicate with one another if required. The main memory (CMY) comprises a plurality of memory banks (MB) each having its own memory control which controls its own memory bank (MB) independently of the memory control of the remaining memory banks (MB). Time frames having time slots or time channels are set up in accordance with the time-division multiplex principle on the bus or busses of the bus system (B:CMY). One or more of the time channels are respectively firmly allocated to each memory control. For the purpose of quasi-simultaneous access to the different memory banks (MB), time slots or time channels can be allocated in each case to a plurality of the processors (CP, IOC). <IMAGE>
Patent FI-853681-L (FI)
Inventor: GREISER WOLFGANG
IPC: D04H1/498
Filed: 1985-09-25
Abstract: A multilayered fabric which when used as support material for built-up roofing and sealing membranes shows not only good fire properties but also improved mechanical properties is obtained by needling together two preconsolidated fibre webs, one of which consists of synthetic fibres and the other of mineral fibres. The needling produces a strong positive bond between the two webs, which prevents the parting of the two layers under extreme thermomechanical conditions.
Patent IE-811329-L (IE)
Title: Derivatives of mercaptoacylprolines and pipecolic acids.
IPC: C07D211/38
Filed: 1981-06-16
Abstract: Azido, imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids having the formula <CHEM> wherein -NR1-R2 is azido or R1 and R2 are the same or different and are hydrogen, alkyl, cycloalkyl, 1-adamantyl, aryl, arylalkyl, alkylcarbonyl, arylcarbonyl, arylalkylcarbonyl, alkylsulfonyl, arylsulfonyl, or arylvinylcarbonyl, or together with the nitrogen atom to which they are attached R1 and R2 are 1-pyrrolidinyl, 1-piperidinyl, 1-homopiperidinyl, 4-morpholinyl, 4-alkyl-1-piperazinyl, 4-aryl-1-piperazinyl, 1-imidazolyl, 1-pyrrolidinyl-2,5-dione, 3-alkyl-1-pyrrolidinyl-2,5-dione, 3-aryl-1-pyrrolidinyl-2,5-dione, 1-piperidinyl-2,6-dione,3-alkyl-1- piperidinyl-2,6-dione, 3-aryl-1-piperidinyl,2-6-dione, 2H-isoindol-2-yl-1,3-dione, hexahydro-2H-isoindol-2-yl-1,3-dione, 2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl, 1,1,3-trioxo-1,2-benzisothiazol-2(3H)-yl, or 1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl; R3 is hydrogen, alkyl, aryl, arylalkyl, or a hydrolyzable acyl protecting group; R4 is hydrogen, alkyl, alkylthio, or trifluoromethyl; R5 is hydrogen, alkyl, or arylalkyl; n is 0, 1 or 2; and p is 1 or 2; or a salt thereof, or symmetrical dimer thereof are useful for the treatment of hypertension.
[EP0042639A2]
Patent IE-42335-L (IE)
Title: Aralkoxyphenyl-bis-aryl-alkylaminoalkanes
IPC: C07C231/00
Filed: 1975-08-01
Abstract: Compounds of the formula I which lower blood pressure and reduce the heart rate <IMAGE> are prepared, in which each of the symbols Ar1, Ar2 and Ar3 denotes a phenyl radical which is unsubstituted or substituted by one or more lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino, mono-lower-alkylamino or di-lower-alkylamino, aminomethyl, mono-lower-alkylaminomethyl or di-lower-alkylaminomethyl groups or one or more halogen atoms, Ph is a phenylene radical which can optionally be substituted by one of the substituents mentioned for Ar1 and n is a number from 0 to 4, and each of the symbols m and p represents a number from 1 to 4, r is the number 1 or 2, and R1 is hydrogen or hydroxyl, and salts of these compounds. These are obtained by reduction of a compound which contains the group of the formula -CO-Cp-1H2p-2- in place of the group -CpH2pin the formula.
[GB1504604A]
Patent IE-38435-L (IE)
Title: Signal detection circuit
IPC: H03K3/0231
Filed: 1973-10-29
Abstract: 1455253 Semiconductor pulse discriminating circuits DUNLOP Ltd 30 Oct 1973 [4 Nov 1972 19 May 1973] 50915/72 and 23980/73 Heading H3T A differential amplifier A changes its output from one to the other of two possible states when a pulse at E overcomes the D.C. bias maintained by voltage divider R1, R13, R6 across the amplifier inputs I, NI, one of which is held by C1 from responding to pulse inputs. Feedback R11, C2 renders the amplifier monostable, and the circuit is also arranged to hold the amplifier output in its other state if the D.C. level at E changes by a large enough amount to indicate a fault. Low tyre pressure signals in a motor vehicle are received by coils S1 to S4 in the form of pulses. A negative pulse from S1 &c. reaches the inverting input I of amplifier A to trigger the monostable, but is prevented from reaching the non- inverting input NI by capacitor Cl. Until the monostable resets it is insensitive to further pulses at E, and its output pulses may operate an alarm. A change in D.C. conditions, however, due to open- or short-circuiting of a coil or coils 51 to 54 appears as a change in voltage across R13, which triggers the output of the amplifier to the "other" (high) level where it remains while the D.C. condition persists. Diodes D1, D2 limit the positive and negative savings at inputs I, NI arising from open and short circuits respectively; and the non-limited input continues to swing until the necessary voltage differences appear (I lower than NI) to trigger the amplifier output to the said high condition. To provide discrimination against extraneous pulses at the input, a discriminator may be included Fig. 2, not shown) which responds only to the particular form of the tyre pressure pulses, namely a larger pulse flanked by two smaller pulses of polarity opposite to the larger one. In the discriminator the pulses are amplified (IC1) and separated by diodes (D3, D4) to charge opposite sides of a capacitor (C5). Only if the middle pulse is sufficiently large does a voltage divider (R20, R21) across the capacitor produce an output to the monostable (IC2, R25, C8).
[GB1455253A]
Patent IE-902009-L (IE)
Title: Organic stabilisers
IPC: C08K/
Filed: 1990-06-05
Abstract: A novel class of organic stabilizers for 3-isothiazolones is disclosed, comprising one or more of dialkyl and dicycloalkylcarbodiimides, aryliodinedicarboxylates, acetals of arylaldehydes, acetals of malondialdehydes, ketals of dialkylacetamides, ketals of 4-alkoxyketones, trispiperidinylphosphine oxide, 1,3,5-dialkyl-1,3,5-triazacyclohexane, 1,8-bis(N,N-dialkyl)naphthalene diamines, 1,4-diaza(2,2,2)-bicyclooctane and alkylated derivatives.
Patent IE-43757-L (IE)
Title: Cable joint protecting structure
IPC: H02G15/24
Filed: 1975-09-24
Abstract: To simplify assembly and to achieve a fool-proof sealing and fixing of the connecting point of elongate objects, a heating device is installed in the enveloping device which, at least in certain sections, is capable of recovering its shape under heat. The said heating device has an electrically conducting polymer material with a positive temperature coefficient of resistance, in order to avoid undesired and harmful overheating. If a current flows through the heating device, the heat thus generated causes the enveloping device to recover its shape and, after recooling, fixes the connecting point in a sealing manner. The fool-proofness is of significance in the case of electrical equipment and installations, quite particularly in the case of electronic equipment and installations. <IMAGE>
[GB1529353A]
Patent IE-892110-L (IE)
Title: Enzymatic resolution process
IPC: C12R1/845
Filed: 1989-06-29
Abstract: A novel enzymatic resolution process for preparing resolved compounds of the formula <CHEM> with improved yields and high optical purity is disclosed. Compounds of formula I min are useful, for example, as intermediates for the preparation of physiologically active compounds, e.g. captopril.
[EP0350811A2]
Patent IE-852128-L (IE)
Title: Oral compositions
IPC: A61K8/34
Filed: 1985-08-29
Abstract: Oral compositions which exhibit antimicrobial activity containing hexedine and a pharmaceutically acceptable zinc compound.
Patent IE-812231-L (IE)
Title: Benzofuran ethanolamine derivatives
IPC: A61P29/00
Filed: 1981-09-25
Abstract: A compound of formula (I): <IMAGE> wherein R1 and R2 are hydrogen or methyl, R3 is hydroxy, hydroxyalkoxy, benzyloxy or X-Y-Z wherein (i) X is a bond or oxygen, Y is C1-6 straight or branched alkylene, and Z is hydrogen or carboxy; or (ii) X is a bond or moiety -O-CH2-, Y is C2-6 straight or branched alkenylene, and Z is carboxy; and R4 is an optional substituent, and n is 1, 2 or 3, their esters, amides and salts, are anti-obesity, hypoglycaemic, anti-inflammatory and platelet aggregation inhibiting agents.
[US4432993A]
Patent IE-782250-L (IE)
Title: Arrangement for mounting a dental superstructure
IPC: A61C13/263
Filed: 1978-11-15
Abstract: An arrangement for the shock-absorbent mounting and support of a dental superstructure, such as a tooth crown, a fastening element for dental bridges and the like, on an artificial tooth having an implantable root and an intermediate member of a tissue-compatible material facilitating a sealing contact with the gingiva, a mounting member for the dental superstructure having a detachable threaded connection interconnecting the intermediate member with the mounting member. A rockable support encompasses the threaded connection so as to form a hollow space there-about, the rockable support extending into a lip sealingly engaged along an outer edge on an upper surface of the intermediate member.
[US4215986A]
Patent IE-902392-L (IE)
Title: Image enhancing surgical staple
IPC: A61B17/068
Filed: 1990-06-29
Abstract: A biocompatible metallic surgical staple formed from a non-magnetic components and comprised of more than 50% titanium by weight is described. The staple is formed from at least 90% titanium and includes a 6% aluminum and 4% vanadium. It has been found that the low density, high strength and non-magnetic properties of the present staple make it desirable for magnetic-resonance imaging scanning.
[EP0406014A1]
Patent IE-812490-L (IE)
Title: Cooling glass forming mould
IPC: C03B9/38
Filed: 1981-10-23
Abstract: A distributing arrangement for a pressurized cooling fluid, especially air, for cooling a forming tool of a machine for forming thermoplastic material, especially molten glass, wherein the forming tool includes at least one split mold including mold segments which are respectively mounted on mold segment holders for movement therewith relative to one another and each of which is provided with a plurality of fluid channels for the flow of the pressurized of fluid channels for the flow of the pressurized cooling fluid therethrough, comprises a fluid distributing box including for each of the mold segments at least two branch channels individually communicating with at least one of the fluid channels when the distributing box is mounted on the mold segment holder. The branch conduits can either directly communicate with the fluid channels across an interface formed by juxtaposed connecting and opposing surfaces of the distributing box and the associated mold segment, or a connecting box including a plurality of connecting channels may be interposed between the distributing box and the respective mold segment, in which case the interface is provided between the distributing and connecting boxes. The connection at the interface is established by merely resting the connecting surface on the opposing surface which has a complementary configuration to the connecting surface.
Patent IE-802535-L (IE)
Title: 1-aminopropan-2-ols
IPC: C07D333/80
Filed: 1980-12-04
Abstract: Derivatives of 1-aminopropan-2-o1 which are useful in the treatment and control of cardiac disorders in warm-blooded mammals. The process of manufacture and pharmaceutical compositions.
[US4339450A]
Patent IE-782574-L (IE)
Title: Determining the velocity of acoustic waves in earth¹formations
IPC: G01V1/50
Filed: 1978-12-29
Abstract: To determine the velocity of acoustic wave energy propagating in formations surrounding a borehole (14), a transmitter (16) periodically transmits acoustic wave energy into the surrounding formations. This energy is received at a plurality of spaced receivers (18.1-18.4). A first portion of the signal from the receiver 18.1 is then correlated with respective first portions of the signals from the other receivers (18.2-18.4) the time reference for the correlation of each of the first portions of the signals from the other receivers (18.2-18.4) being selected, relative to the time reference of the signal from the receiver 18.1, in accordance with the spacing of the receivers (18.1-18.4) and a first estimated velocity. The correlation is repeated for four more estimated velocities, and a velocity value which yields the best correlation is selected by interpolation as a first provisional velocity. The correlation for several assumed velocities and interpolation is then performed on second portions of the signals from the receivers (18.1-18.4) to obtain a second provisional velocity. An output velocity is then determined as a function of the first and second (and possibly other similarly-generated) provisional velocities. The velocity of the compressional component and/or the shear component of the acoustic wave energy can be obtained. <IMAGE>
[GB2012422A]
Patent IE-44133-L (IE)
Title: Process for preparing 2-cephem compounds.
IPC: C07D501/24
Filed: 1976-11-26
Abstract: 3-Acyloxymethyl-delta<2>-cephem compounds of the formula (I) <IMAGE> in which the substituents are defined in Claim 1, are obtained by reacting a 3-exomethylenecepham sulphoxide with a mixture of an acyl compound and of an appropriate anhydride at a temperature from 70 to 140 DEG C. The 3-acyloxymethyl-delta<2>-cephem esters of the formula I are generally valuable intermediates in the preparation of cephalosporins with antibiotic activity.
[GB1566526A]