baber/WOPTO huggingface dataset:
Patent PT-965801-E (PT)
Inventor: LONGHI GIUSEPPE DE
IPC: F28D1/03
Filed: 1999-05-11
Abstract: The independently operating and mobile radiator comprising a body (2) having a plurality of radiating members each defined by at least a first metal plate (3) and a second metal plate (3) mutually associated and by at least one central portion (5) wherein heated fluid circulates at a temperature preset by heating means (6), the radiating members being mutually connected through passage hubs (7) for circulating the fluid inside the body, characterized in that each radiating member has at least one region of its surface, external to the central portion wherein said heated fluid circulates, having a wall thickness (S) substantially equal to the thickness of the first or second metal plate. <IMAGE>
Patent PT-1071704-E (PT)
Inventor: SORSA TIMO
IPC: A61K38/00
Filed: 1999-03-17
Abstract: The present invention relates to novel matrix metalloproteinase (MMP) inhibitors and down-regulators, to a process for the preparation of these inhibitors, to pharmaceutical compositions comprising these inhibitors/down-regulators, to the use of the novel MMP inhibitors for the manufacture of pharmaceutical and research preparations, to a method for inhibiting and down-regulating MMP-dependent conditions either in vivo or in vitro, to a method for inhibiting formation, synthesis, expression activations, and/or functions as well as actions of matrix metalloproteinases, and to the use of the novel MMP inhibitors and down-regulators in biochemical isolation and purification procedures of matrix metalloproteinases.
Patent PT-1109817-E (PT)
Inventor: BELMANT CHRISTIAN
IPC: A61K35/12
Filed: 1999-08-27
Abstract: The invention provides compounds comprising at least one phosphohalohydrin group of the formula: where X is a halogen selected from among I, Br, Cl, R1 is selected from among —CH3 and —CH2—CH3, Cat+ is an organic or inorganic cation, and n is an integer between 2 and 20, processes for the production thereof and uses theroef, in particular therapeutic uses and for activating primate Tγ9δ2 lymphocytes.
Patent SG-3788-G (SG)
Title: Tilting mechanism for a chair
IPC: A47C1/022
Filed: 1988-01-08
Abstract: PCT No. PCT/GB84/00272 Sec. 371 Date Apr. 3, 1985 Sec. 102(e) Date Apr. 3, 1985 PCT Filed Aug. 8, 1984 PCT Pub. No. WO85/00734 PCT Pub. Date Feb. 28, 1985.A tilting mechanism for a chair includes a stationary support frame member for connection to an upright chair column, a seat frame member for mounting a seat portion of the chair, and a backrest frame member for mounting a backrest portion of the chair. The seat frame member defines a downwardly directed channel and respective horizontal pivots between parallel sides of the channel to pivotally mount the seat frame member to the support frame member, and the backrest frame member to the seat frame member, allowing the tilt of the seat and the backrest to be adjusted. The support frame member and the backrest member are connected by links to respective toothed quadrant members pivotally mounted in the channel. Locking levers in the channel are biased normally to lock the quadrants in position, but a control lever with a cam device thereon is operable to release either or both locking levers from the quadrants when adjustment of the tilt of the seat or backrest is required, the cam device lifting one or both locking levers against their bias depending on the position of the control lever.
Patent SG-12986-G (SG)
Title: Piezoelectric-drive system, especially for focussing systems
IPC: H01L41/08
Filed: 1986-02-15
Abstract: 1. A piezoelectric drive arrangement comprising a control circuit for effecting controlled deflections, consisting of a plurality of piezocrystal elements, which are adapted to have electric control voltages separately applied to them and are arranged one behind the other and the individual deflections of which add up, characterized in that a digital control voltage (+- U1 , +- U2 , +- U3 ) is adapted to be applied to each piezocrystal element (2, 3, 4; 10) for a control of the piezoelectric drive arrangement, and said digital control voltage is derived from a continuously applied drive voltage (Uop ) and is applied to the piezocrystal element with a polarity which is determined by a decoder in dependence on a logical input signal (+- Ucontrol ) in order to control the respective piezocrystal element for a temporary deflection to a hysteresis end point.
Patent SG-79784-G (SG)
Title: 1-(dihydroxyphenyl)-2-amino-ethanol derivatives;preparation,compositions and intermediates
IPC: C07C239/00
Filed: 1984-11-09
Abstract: New bronchospasmolytically active compounds exhibiting long duration of action and reduced undesired side effects of the structural formulaand therapeutically acceptable salts thereof, in which formula R is selected from the group consisting of -C(CH<sub>3</sub>)<sub>3</sub>,andR<sup>1</sup> is selected from the group consisting of H and <sub>R2</sub>, R<sup>2</sup> represents the radical of the formulawherein R<sup>3</sup> is selected from the group consisting of(a) H(b) alkyl groups containing 1-3 carbon atomswherein R<sup>5</sup> is selected from the group consisting of(a) OH(b) alkoxy groups containing 1-3 carbon atoms and whereinR<sup>4</sup> is selected from the group consisting of(a) H(b) alkyl groups containing 1-3 carbon atoms, with the proviso that R<sup>3</sup> and R<sup>4</sup> are combined as follows:processes for the preparation thereof, chemical intermediates at their preparation, pharmaceutical preparations containing them, and their medicinal use.
Patent IE-45013-L (IE)
Title: Purifying insulin
IPC: A61K38/00
Filed: 1977-01-11
Abstract: The present invention relates to monocomponent insulin purified to such a degree that it shows only a single component when analyzed by amide gel electrophoresis using a gel containing 15% polyacrylamide. It, furthermore, relates to a method of preparing such insulin from an insulin containing raw extract prepared from pancreas glands, consisting in the working up of the extract in such a manner that the insulin is maintained in dissolved state during the whole processing, without change of phase, until the final recovery of the insulin, the undesired substances being from the beginning of the process until the end removed from the different solvents used. A preferred method comprises removal of fat from the extract by cooling to a temperature below -25.degree.C and separation of the crystallized fat, concentration of the extract and simultaneous removal of impurities present in the extract, both substances having a larger molecule than insulin and substances having a smaller molecule than insulin, by means of reverse osmosis plant for removal of colouring substances and salts, further purification by means of ion exchange and recovery of the insulin from the concentrated purified solution resulting from the ion exchange treatment by precipitation with metal ions under strong cooling. The monocomponent insulin may be used in insulin preparations of any kind for clinical use.
[CA1112639A]
Patent IE-820075-L (IE)
Title: 4-amino-chloroquinolines
IPC: C07D215/46
Filed: 1982-01-15
Abstract: 4-Amino-chloroquinolines of the formula:   <IMAGE>   in which R1 represents a hydrogen atom or an alkyl radical (1 to 5 carbon atoms), and R2 represents an alkyl radical (1 to 5 carbon atoms) optionally substituted by a dialkylamino group, or a phenyl radical optionally substituted by one or more carboxy and hydroxy radicals and alkyl radicals (1 to 4 carbon atoms) optionally substituted by a dialkylamino group, are prepared by the condensation of an amine of the formula:   <IMAGE>  with a chloro-1,2,3,4-tetrahydroquinolin-4-one of the formula:   <IMAGE> with aromatization of the tetrahydroquinoline, the reaction being carried out in the presence of a ruthenium based catalyst on a support. The 4-amino-chloroquinoline products are useful as pharmaceuticals.
Patent IE-38831-L (IE)
Title: Isoindolinone derivatives
IPC: C07D209/48
Filed: 1974-02-07
Abstract: Isoindolin-1-one derivatives carrying on the nitrogen atom in the 2-position a phenyl or pyridyl radical, optionally carrying one or two substituents selected from halogen, alkyl (C.sub.1 -C.sub.4), alkoxy (C.sub.1 -C.sub.4), cyano and trifluoromethyl, and in the 3-position a grouping --O--T--NR.sub.1 R.sub.2 wherein T is alkylene (C.sub.2 -C.sub.6), and R.sub.1 and R.sub.2 represent hydrogen or alkyl (C.sub.1 -C.sub.4), are new compounds possessing pharmacodynamic properties and are useful as anti-arrhythmic agents.[US4001271A]
Patent IE-870483-L (IE)
Title: Consistometer for the analysis of rheological change (flow¹characteristics)
IPC: G01N11/00
Filed: 1987-02-25
Abstract: A consistometer usable at a work site comprises a stationary receptacle (9) which is placed in an enclosure (3) defined by a consistometer casing (2) and is provided with a stirrer (17) with a rotary drive spindle (18). The casing has an extension (20) in which there is arranged an intermediate shaft (23) angularly fast with a torque receiver (22) of a magnetic type actuated from outside the extension by a driven torque transmitter (21). Shaft (23) is angularly fast with a coupling device (24) for engagement with the spindle simply by the spindle being introduced into the coupling device when the receptacle is placed in the casing.
[US4736624A]
Patent IE-810508-L (IE)
Title: Senior for oxygen-combustibles gas mixtures
IPC: G01N27/416
Filed: 1981-03-10
Abstract: A molten carbonate electrochemical cell operating at a temperature between 400 DEG and 700 DEG C. is used to remove O2 in combination with CO2 from an oxygen/combustibles gas mixture to provide a low temperature measurement of the oxygen content of the gas mixture.
[US4285790A]
Patent IE-820536-L (IE)
Title: Stabilized insulin preparation
IPC: A61K38/28
Filed: 1982-03-09
Abstract: Novel pharmaceutical preparations of dissolved zinc insulin having improved physical stability are prepared by incorporating therein a calcium or magnesium salt so as to provide a solution containing essentially ionised calcuim or magnesium.The novel insulin preparations are particularly adapted for use in continuous insulin delivery equipment.
Patent IE-830602-L (IE)
Title: Working depth control system for a tractor with a ground¹working implement
IPC: A01B67/00
Filed: 1983-03-21
Abstract: A tractor (10) includes a hitch (26) for pulling a ground-working implement. A hydraulic cylinder (34) is extensible and retractable to lower and raise the implement. A control syytem (50) senses operating parameters, including wheel slip, engine speed, draft force and implement or rockshaft position. Error signals are derived from the sensed wheel slip, engine speed and draft force and correspond set point signals. The error signals are combined into a composite or combined error signal. The larger of (a) the combined error signal and (b) a separately determined position error signal. is selected and converted to a pulsewidth modulated valve control signal which is applied to a control valve (42) which then actuates the cylinder to move the implement to reduce the magnitude of the selected error signal. Certain set point signals are derived from the corresponding parameter signals themselves.
Patent FI-823007-L (FI)
Inventor: HITZEL VOLKER
IPC: A61K31/64
Filed: 1982-08-31
Abstract: Sulfonylureas of the formula   <IMAGE>   in which Y denotes alkylene having 2-3 C atoms, R denotes alkyl having 1-4 C atoms, R1 denotes hydrogen, chlorine or methyl, and R2 denotes alkyl having 3-6 C atoms, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, cycloalkenyl, alkylcycloalkenyl or cycloalkenylalkyl, each having 5-8 C atoms, and their physiologically tolerated salts, and processes for their preparation and medicaments prepared therefrom.
Patent FI-824307-L (FI)
Inventor: BURBA CHRISTIAN
IPC: C08G18/10
Filed: 1982-12-15
Abstract: The method of hardening a glycidyl compound with a polyether urethane urea amino hardener is disclosed, said hardener being prepared by reacting (1) a blocked prepolymer prepared by reacting a phenolic compound with the reaction product of a polyether polyol with an excess of polyisocyanate, with (2) a polyfunctional amino compound.
Patent FI-830618-L (FI)
Inventor: THOESE KLAUS
IPC: B05D5/04
Filed: 1983-02-24
Abstract: Disclosed is a drafting film which comprises a plastic base provided on at least one surface with an adhesive layer and a pigmented coating system which comprises a pigmented layer and a top layer or a pigmented layer alone. In particular, the pigmented coating system comprises an acrylate or methacrylate copolymer comprising at least 50 percent by weight of an ester monomer, the alcohol component of which has a chain length of at least four carbon atoms, an antistatic agent comprising a polymeric sulfonic acid salt in combination with homopolymers or copolymers of vinyl acetate, or partially hydrolyzed polyvinyl acetate, cross-linking agents and delusterants. Also disclosed is the use of the drafting film for producing diazo sensitized film.
Patent FI-831315-L (FI)
Inventor: LELOUX ARNOLDUS WILLEM JAN
IPC: B29C53/00
Filed: 1983-04-19
Abstract: A method of making seals in tubular web provided with side gussets, in which method, after making the seals, sensors for the inner gusset edges are withdrawn outwardly over a certain distance, the position of the sealing devices remaining unchanged, and after transport of the tubular web, the sensors are moved inwardly again and the new position of the inner gusset edges is observed, subsequently, when a difference is observed as compared with the previous time, the position of the sealing devices is brought into correspondence with this observation before making the next seal. A device for making seals in tubular web provided with side gussets, guide members and gusset sealing devices which are movable independently of one another in lateral direction, and in which individual means are provided to bring the position of the gusset sealing devices in correspondence with the position of the guide members in case the latter, after making a seal and displacing the material one or more unit bag lengths, observe a difference as compared with the previous time.
Patent FI-844557-L (FI)
Inventor: RASMUSSEN MIRELLA EZBAN
IPC: C07K14/755
Filed: 1984-11-20
Abstract: Production of a very high purity concentrate of the antihaemophilic Factor VIII (AHF) by precipitation of an aqueous solution of cryoprecipitate from blood plasma in a first step with such an amount of polyethylene glycol (PEG), preferably about 4% by weight, as will precipitate a substantial amount of the present fibrinogen, subjecting the fibrinogen-free solution to a second precipitation step with preferably about 12% by weight of PEG in the presence of a salting-in agent, such as an amino acid, in particular lysine or arginine, or a carbohydrate, and then recovering the precipitate with a concentrated content of the present Factor VIII. The obtained Factor VIII concentrate with a very low content of immunoglobulins and other plasma proteins has a solubility in an aqueous injection medium of 45 to 500 units/ml and a high specific activity of up to 50 units/mg protein. <IMAGE>
Patent IE-791115-L (IE)
Title: Genetically engineered protein.
IPC: C12P21/04
Filed: 1979-08-08
Abstract: A plasmid or phage gene for a periplasmic or extracellular bacterial protein is cleaved, a double-stranded DNA sequence coding for a selected protein or portion thereof from a eukaryotic cell such as insulin is inserted in that cleaved gene by recombinant DNA techniques and used to transform a bacterium, and the excreted selected protein is collected.
Patent IE-32417-L (IE)
Title: Guanidines
IPC: C07C281/18
Filed: 1968-10-14
Abstract: 1,223,491. Aminoguanidine derivatives. AMERICAN HOME PRODUCTS CORP. 22 Feb., 1968 [13 Oct., 1967], No. 8629/68. Heading C2C. The invention comprises compounds of formula and their acid-addition salts, wherein X is a direct bond, CH 2 , CH 2 CH 2 or CH: CH; R<SP>1</SP>, R<SP>2</SP> and Y are each halogen, NO 2 , amino, alkylsubstituted amino, alkyl, alkoxy, benzyloxy (possibly halogen-substituted), OH or CF 3 , n is 0, 1, 2 or 3 (or n is 1 and Y+R<SP>2</SP> form together O-CH 2 -O), R<SP>3</SP> is H, C 3-5 cycloalkyl, alkyl, ethynyl, allyl or benzyl, and R<SP>4</SP>, R<SP>5</SP>, R<SP>6</SP> are each H or alkyl (or when R<SP>6</SP> is H, then R<SP>4</SP>, R<SP>5</SP> and the attached N atoms may form an imidazoline ring), the alkyl and alkoxy groups containing 1-6 C atoms, but excluding 2,6-dichlorobenzylideneaminoguanidine (A). These compounds are prepared by reacting the corresponding carbonyl compound (B) with an aminoguanidine or its salt, or by heating B-thiosemicarbazone with NH 3 , or by reacting B-hydrazone with CNNH 2 . Starting materials.-2,5-Dibromopropiophenone and 2,5-dichlorobutyrophenone are prepared by a Friedel-Crafts reaction. 2,6-Dichloro-3- ethoxy- and 2,4,6-trichloro-3-ethoxy-benzaldehydes are prepared from the 3-hydroxy compounds with Et 2 SO 4 + K 2 CO 3 . Pharmaceutical and veterinary compositions for oral or parenteral administration comprise compounds of the above formula (including A), which have hypotensive, antihypertensive, antibacterial, CNS (e.g. anti-reserpine, anti-morphine, anti-oxytremorine, depressant or mydriatic), analgesic, diuretic, hyperglycaemic, anti-inflammatory, anorectic, stimulant, psychic energizing, tranquilizing and anti-Parkinson activity.
[GB1223491A]
Patent IE-861448-L (IE)
Title: Apertured macroscopically expanded 3-dimensional web with¹breathability and reduced fluid transmission
IPC: A61F13/49
Filed: 1986-05-30
Abstract: @ The present invention pertains, in a particularly preferred embodiment, to an apertured, macroscopically expanded, resilient three-dimensional polymeric web which is believed to have particular utility as a breatheable barrier for a disposable bandage such as a diaper. The web preferably comprises a deeply drawn three-dimensional structure containing a multiplicity of debossments of macroscopic (i.e., visibly perceivable by the normal human eye at a perpendicular distance of about one foot) cross-section, each of said debossments originating as an aperture in a first surface of the web and having a continuously interconnected side wall extending in the direction of a second, remotely located parallel surface of the web. The side wall of each debossment terminates to form an end wall in the second surface of the web. The end wall includes a multiplicity of apertures, each of said apertures being sized and shaped to independently support an aqueous fluid meniscus. The smaller apertures in each end wall are so spaced relative to all adjacent apertures in the end wall that the aqueous fluid menisci supported in the apertures do not contact one another or the side wall. In a disposable absorbent bandage context, the second surface of the web containing the end walls with small apertures therein is placed in contact with the absorbent core portion of the bandage and the surface of the web in which the debossments originate is oriented so as to contact the wearer's outer garments in use.
Patent IE-38228-L (IE)
Title: Discriminator circuits
IPC: G01N21/00
Filed: 1973-09-10
Abstract: 1404239 Semi-conductor gating and limiting circuits RANK ORGANISATION Ltd 19 Sept 1973 [25 Sept 1972] 44207/72 Heading H3T An input signal is blocked if it changes too fast or its amplitude falls the wrong side of a reference voltage. The reference threshold is set at 27, and if the input amplified at 15 falls below this threshold, the output of an amplifier 25 goes negative to turn off F.E.T. 18, which normally passes the signal to output amplifier 20. F.E.T. 18 is alternatively turned off by a negative output from differentiator 14. Amplifier 30 has one input slowed by C34, R33 so that the inverting input operates first on a signal change followed by the non- inverting input; this gives a waveform (Fig. 2c, not shown) equivalent to differentiation. Diodes 36, 37 and amplifier 35 full wave rectify the output of 30.
[GB1404239A]
Patent IE-45458-L (IE)
Title: Miller-encoded message decoder
IPC: H04L25/49
Filed: 1977-08-03
Abstract: A device for decoding a Miller-encoded message in the form of binary data at a clock frequency F. The decoder comprises: a transition detector which provides a very short pulse at each transition in the encoded message; first means controlled by a local clock at frequency F to pass only those short pulses which have the same phase; second means for stretching the short pulses passed by the first means to a duration of (1/2F); a local clock phase lock loop acting on a voltage-controlled oscillator of the local clock and responsive to the output signal of the second means; and a flip-flop to sample the output of the second means under the control of the local clock.
[US4112383A]
Patent IE-45370-L (IE)
Title: Allyl-acrylic monomers and derived polymers
IPC: C07C239/00
Filed: 1977-08-22
Abstract: Novel allyl-acrylic monomers of the formula: <IMAGE> wherein R is a C1-4 alkylene group and R1 is hydrogen or methyl, are described. The preferred monomer is that in which R is ethylene and R1 is methyl. When subjected to conventional free radical polymerization, in one stage or two stages, these monomers give transparent polymers having good mechanical properties, particularly hardness.
[US4199526A]
Patent IE-781765-L (IE)
Title: Chrome-tanning.
IPC: C14C3/28
Filed: 1978-09-01
Abstract: In the chrome-tanning of animal skins and hides by pretanning the pickled pelts with chromium (III) salts, followed by full tanning with chromium (III) salts and acid-binding agents, the improvement which comprises effecting full tanning with the reaction of product at least one of formic acid and a formate with a basic chromium (III) sulphate, at least 2 moles of formate plus formic acid being used per mole of Cr2O3 in the chrome-tanning agent used for full tanning, the total input of chromium oxide being from about 1.0 to 1.8%, based on the weight of the pelts, and tanning being carried out with a liquor volume of at most 100%, based on the weight of the pelts, up to a final pH-value of at least 4.0.
[US4211529A]
Patent IE-851768-L (IE)
Title: Recorded information verification system
IPC: G11B23/28
Filed: 1985-07-15
Abstract: A system for recording and reproducing an audio, video and/or data message with facility for automatically indicating lack of faithful reproduction of the message originally recorded, which comprises deriving a first data signal representative of the message, generating correlation signal bursts whose interval is determined by a characteristic of the data signal, recording the message and data and correlation signals on a recording medium, recovering from the recording medium the message for playback and the correlation signal, deriving a second data signal from the recovered message and predicting from the second data signal the instant when the recovered correlation signal bursts should occur, and providing an indication whenever the recovered correlation signal bursts do not occur as predicted.
[WO8600745A1]
Patent IE-901781-L (IE)
Title: Copolymers of monoethylenically unsaturated dicarboxylic¹acids, detergents
IPC: C09K23/52
Filed: 1990-05-17
Abstract: Copolymers of aliphatic monoethylenically unsaturated dicarboxylic acids and unsaturated monomers have been formed by gradually and simultaneously adding monomers and initiator, to a reaction vessel initially containing water at a temperature suitable for polymerization. The polymerization reaction is conducted in the presence of a metal salt activator. The copolymers have consistent compositions and superior properties as antiscalants, dispersants and incrustation inhibitors.