baber/WOPTO huggingface dataset:
Patent NZ-228688-A (NZ)
Title: Amides of cycloalkane-1,2-dicarboxylic acids and pharmaceutical compositions thereof
Inventor: TURBANTI LUIGI
IPC: C07C259/06
Filed: 1989-04-11
Abstract: The amides of cyclomethylen-1,2-bicarboxylic acids having the formula: <CHEM>  m is 0 or 1 and n is an integer varying between 0 and 3, are endowed with ACE-inhibiting activity and are thus therapeutically useful as anti-hypertension agents. For their preparation cyclomethylene-1,2-bicarboxylic acid or a derivative thereof is condensed either with an amino derivative containing a protected hydroxamic group, or with an aminoester, and then in the former case the protecting group is removed, or in the latter case is reacted with either hydroxylamine or N-alkylhydroxylamine.
Patent NZ-230875-A (NZ)
Title: Herbicidal composition comprising n-phosphonomethylglycine and an alkyl glucoside
Inventor: HEATH ROGER PALMERSTON
IPC: A01N25/30
Filed: 1989-10-03
Abstract: A herbicidal composition comprises an aqueous solution of an N-(phosphonomethyl)glycine herbicide which comprises an effective quantity of at least one alkyl glucoside, the alkyl glucoside having an alkyl: glucose molar ratio of from 1:1.3-1:1.6. Preferably, the alkyl glucose ratio is 1:1.4 and the alkyl glucoside comprises from 20% - 45% by weight of the total non-volatile context of the composition. The composition are especially useful for killing grass weeds.
Patent NZ-248909-A (NZ)
Title: Rapamycin esters of carbamic acid derivatives and medicaments thereof
Inventor: KAO WENLING
IPC: A61K31/395
Filed: 1993-10-11
Abstract: The invention concerns a compound of the structure <CHEM>  wherein R<1> and R<2> are each, independently, hydrogen,  -CONH-Ä(CR<3>R<4>)m(-A-(CR<5>R<6>)n)pÜq-B; <CHEM> R<3>, R<4>, R<5>, R<6>, R<9> and R<10> are each defined substitutents, and R<3-6> may each also represent hydrogen, B is alkenyl of 2-7 carbon atoms, alkynyl of 2-7 carbon atoms, hydroxyalkyl of 1-6 carbon atoms, alkylthioalkyl of 2-12 carbon atoms, alkylaminoalkyl of 2-12 carbon atoms, dialkylaminoalkyl of 3-12 carbon atoms, -OR<7>, -SR<7>, -CN, -COR<7>, -CONHR<7>, -OSO3R<7>, -NR<7>R<8>, -NHCOR<7>, -NHSO2R<7>, or Ar; A is -CH2-, -NR<7>-, -O-, -S-, -SO-, -PR<7>-, -NHCO-, -NHSO- or -P(O)(R<7>)-; Ar is naphthyl, pyridyl, quinolyl, isoquinolyl, quinoxalyl, thienyl, thionaphthyl, furyl, benzofuryl, benzodioxyl, benzoxazolyl, benzoisoxazolyl, indolyl, thiazolyl, isoxazolyl, pyrimidinyl, pyrazinyl, imidazolyl, benzopyranyl, benzÄbÜthiophenolyl, benzimidazolyl, benzthiazolyl, benzodioxolyl, piperidinyl, morpholinyl, piperazinyl, tetrahydrofuranyl, or pyrrolidinyl; wherein the Ar group may be optionally mono-, di-, or tri- substituted with a group selected from alkyl of 1-6 carbon atoms, arylalkyl of 7-10 carbon atoms, alkoxy of 1-6 carbon atoms, cyano, halo, hydroxy, nitro, carbalkoxy of 2-7 carbon atoms, trifluoromethyl, amino, dialkylamino of 1-6 carbon atoms per alkyl group, dialkylaminoalkyl of 3-12 carbon atoms, hydroxyalkyl of 1-6 carbon atoms, alkoxyalkyl of 2-12 carbon atoms, alkylthio of 1-6 carbon atoms, -SO3H -PO3H, and -CO2H; PO3H, and -CO2H; <CHEM> is a nitrogen containing heterocycle that may be saturated, unsaturated, or partially unsaturated, and may be optionally mono-, di-, or tri- substituted with a defined substituent, with the proviso that R<1> and R<2> are not both hydrogen;  m=0-6; n=0-6; p=0-1; q=0-1; or a pharmaceutically acceptable salt thereof which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent.
Patent NZ-265267-A (NZ)
Title: Fuel or lubricant composition containing an amine derivative, one substituent being a poly-1-n-alkene radical derived from ethylene and at least one c3-6 alpha-olefin
Inventor: MUELLER HANS-JOACHIM
IPC: C10M133/54
Filed: 1994-04-11
Abstract: PCT No. PCT/EP94/01113 Sec. 371 Date Oct. 23, 1995 Sec. 102(e) Date Oct. 23, 1995 PCT Filed Apr. 11, 1994 PCT Pub. No. WO94/24231 PCT Pub. Date Oct. 27, 1994Fuel and lubricant compositions contain a poly-1-n-alkenylamine as an additive.
Patent NZ-289025-A (NZ)
Title: Antifouling composition comprising substituted 3-butyl-furan-2-one and a carrier
Inventor: STEINBERG PETER
IPC: C09D5/16
Filed: 1995-07-05
Abstract: PCT No. PCT/AU95/00407 Sec. 371 Date Feb. 27, 1997 Sec. 102(e) Date Feb. 27, 1997 PCT Filed Jul. 5, 1995 PCT Pub. No. WO96/01294 PCT Pub. Date Jan. 18, 1996An antifouling composition that comprises an effective amount of a furanone of the structure shown and a suitable carrier therefor. In the figure, substituents R1, R2 and R3 are each a hydrogen atom, a hydroxyl group, an alkyl group containing from 1 to 10 carbon atoms, an ether group containing from 1 to 10 carbon atoms, an ester group containing from 1 to 10 carbon atoms or a halogenated alkene containing from 1 to 10 carbon atoms or R2 and R3 together may comprise an unsubstituted or a halogenated alkene containing from 1 to 10 carbon atoms and R4 is a hydrogen or halogen atom, and a suitable carrier therefor.
Patent NZ-299941-A (NZ)
Title: Beta sulphur-n-hydroxy amides (optionally heterocyclically substituted) and derivatives thereof; medicaments; used as metalloprotease inhibitors
Inventor: BENDER STEVEN LEE
IPC: A61P3/00
Filed: 1996-12-16
Abstract: Compounds of the formula: <CHEM>  wherein:   n is   0, 1 or 2; Y is   hydroxy or XONH-, where X is hydrogen or lower alkyl; R<1>   is hydrogen or lower alkyl; R<2>   is hydrogen, lower alkyl, heteroalkyl, aryl, aralkyl, arylheteroalkyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroaralkyl, heteroarylheteroalkyl, heterocyclo, heterocylo-lower alkyl, heterocyclo-lower heteroalkyl or -NR<6>R<7>, wherein:   R<6> is hydrogen, lower alkyl, cycloalkyl or cycloalkylalkyl, aryl, heteroaryl and heteroaralkyl; R<7> is hydrogen, lower alkyl, cycloalkyl or cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroaralkyl, -C(O)R<8>, -C(O)NR<8>R<9>, -SO2NR<8>R<9>, -SO2R<10>, aryloxycarbonyl, or alkoxycarbonyl; or R<6> and R<7> together with the nitrogen atom to which they are attached represent a heterocyclo group; wherein   R<8> and R<9> are independently hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroaralkyl or heteroalkyl; and R<10> is lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroaralkyl, heteroalkyl or heterocyclo; or     R<1> and R<2>   together with the carbon atom to which they are attached represent a cycloalkyl or heterocyclo group; R<3> is   hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroaralkyl, heteroalkyl or lower alkoxy; R<4> is   hydrogen, lower alkyl, cycloalkyl or cycloalkylalkyl; or R<2> and R<3>   together with the carbons to which they are attached represent a cycloalkyl or heterocyclo group; or R<3> and R<4>   together with the carbon to which they are attached represent a cycloalkyl or heterocyclo group; and R<5> is   lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, or heteroaralkyl; or pharmaceutically acceptable salts or esters thereof exhibit useful pharmacological properties, in particular for use as matrix metalloprotease inhibitors, particularly for interstitial collagenases.
Patent NZ-313115-A (NZ)
Title: Expandible stent
Inventor: LEE MICHAEL J
IPC: A61F2/958
Filed: 1996-07-25
Abstract: stent has a tubular body with longitudinal struts 14 interconnected by multi-bar linkages 16.  The struts inhibit foreshortening of the body and relative rotation between the links in the linkages permits radial expansion.  The links are plastically deformed as they are expanded to maintain the expanded diameter.
Patent NZ-333688-A (NZ)
Title: p-terphenyl compounds suitable as IgE production suppressors
Inventor: KAWADA KENJI
IPC: C07C229/52
Filed: 1997-07-30
Abstract: A compound which suppresses the IgE production in a process from the differentiation of a mature B cell into an antibody-producing cell and the production of an antibody thereby which does not suppress or weakly suppresses the production of IgG, IgM and/or IgA to be produced at the same time, the compound being of formula (I) wherein: R1 - R13 are hydrogen, halogen, lower alkyl, lower alkoxy; X is -O-, -CH2-, -NR14 - or -S(O)p-; and Y is lower alkyl, lower alkenyl.
Patent NZ-334883-A (NZ)
Title: A crystalline substance of cefditoren pivoxil which has desirable thermal storage stability and the production of the same
Inventor: YASUI KIYOSHI
IPC: A61P31/04
Filed: 1997-09-19
Abstract: A crystalline substance of Cefditoren pivoxyl, 7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyimino-acetamido]-3-[(Z)-2-(4-methylthiazol-5-yl)-ethenyl]-3-cephem-4-carboxylic acid pivaloyloxymethyl ester, characterised in that crystalline substance of Cefditoren pivoxyl is of orthorhombic form and has a melting point with decomposition at a temperature in a range of 206.2oC to 215.7oC as evaluated from the peak of thermal absorption shown in the heat flow curve (Figure 1) of the substance determined by a differential scanning calorimeter, that a single crystal of the crystalline substance has a density of 1.21 to 1.23 g/cm and contains 4 molecules of Cefditoren pivoxyl within a unit lattice of the single crystal, that the crystalline substance has a purity of 97% to 98% for the Cefditoren pivoxyl component as measured by liquid chromatography using reverse phase silica gel column and by detection with ultra-violet ray absorption, and that the crystalline substance has a higher thermal stability than the known amorphous substance of Cefditoren pivoxyl.
Patent NZ-335296-A (NZ)
Title: Insect repellent emulsions containingN,N-Diethyl-m-toluamide
Inventor: ROSS JAMIE S
IPC: A61Q17/02
Filed: 1997-11-21
Abstract: An insect repellent emulsion composition comprising: 1)	an insect repelling-effective amount (5 to about 25 percent by weight) of N,N-Diethyl-m-toluamide 2)	water 3)	a film-forming polymer selected from the group consisting of copolymers of octadecene and maleic anhydride, copolymers of 1-triacontane and vinyl pyrrolidone, acrylates/octylacrylamide copolymer, acrylates/PVP copolymer, acrylates/acrylmide copolymer, acrylates/VA copolymer, ethylene/maleic anhydride copolymer, polyisobutene, polyvinyl alcohol, PVP/eicosene copolymer, starch/acryates/acrylamide copolymer, hexanedioic acid polymers and mixtures of any two or more thereof; and about 0.01 to about 5 weight percent of an emulsifier-emulsion stabilizer selected from the group consisting of acryates/C10-30alkyl acrylate crosspolymer, carbomer, methyl vinyl ether/maleic anhydride copolymer, a salt of triethanolamine and stearic acid and mixtures of any two or more thereof 4)	optionally, an emulsifying agent selected from the group consisting of sorbitan stearate, stearic acid, sorbitan oleate, cetyl alcohol, glyceryl oleates, glyceryl stearates, sorbitan sesquioleate, DEA-cetyl phosphate, Oleth-20, PEG-8 distearate, PEG-8 oleate, PEG-2 stearate, sodium laureth sulfate and mixtures of any two or more thereof
Patent NZ-335589-A (NZ)
Title: Projectable target for trap and skeet shooting with sulfur, filler and sulfur modifier for reduced environmental concerns and enhanced properties during use
Inventor: SKEUSE BRIAN
IPC: F41J1/01
Filed: 1999-05-04
Abstract: The friable target of acceptable weight, strength and brittleness to be used for trap or skeet shooting comprising a composition of a) 30-45% sulphur; b) 30-60% of a filler such as sands, gypsums, clays, glass, silicates or rock and c) 0.25-4% of a sulphur modifier such as lignin sulphonate.
Patent NZ-337400-A (NZ)
Title: Use of descarboethoxyloratadine for the manufacture of a medicament for the treatment of urinary incontinence, motion sickness and vertigo
Inventor: MCCULLOUGH JOHN R
IPC: A61P13/00
Filed: 1998-02-24
Abstract: Descarboethoxyloratadine (DCL), descarboethoxyloratadine and ephedrine, amphetamine or a psychostimulant are useful for treating urinary incontinence, vertigo or motion sickness.
Patent NZ-504064-A (NZ)
Title: Isoparaffinic lubricant basestock compositions characterised by extent of carbon chain branching
Inventor: FORBUS THOMAS R
IPC: C10M105/04
Filed: 1998-10-15
Abstract: A liquid hydrocarbon composition, comprising paraffinic hydrocarbon components in which the extent of branching, as measured by the percentage of methyl hydrogens (BI), and the proximity of branching, as measured by the percentage of recurring methylene carbons which are four or more carbons removed from an end group or branch (CH2>4), are such that: i)	BI - 0.5(CH2>4) > 15; and ii)	BI + 0.85(CH2>4) < 45; as measured over the liquid hydrocarbon composition as a whole. Also described is a lubricating oil composition, comprising the liquid hydrocarbon composition described above.
Patent NZ-504155-A (NZ)
Title: Electroluminescent (EL) lighting system for use with gaming machine, control circuitry samples lamp power signals from machine
Inventor: BEVINGTON MARK
IPC: G09G3/30
Filed: 1997-01-23
Abstract: An electroluminescent (EL) lighting system for a gaming machine 104 includes an EL lamp panel 108A that is capable of illuminating the EL lamp cells in the panel in sequence, and can produce an animated display.  The EL lamp control circuitry 101 samples the lamp control signals produced by the gaming machine and used to light the machines own incandescent lamps.  The circuitry 101 uses the lamp control signals to control the sequence of illumination of the EL lamp cells.  The lamp control signals are sampled non-invasively by the signal conditioning circuitry 102.
Patent NZ-504561-A (NZ)
Title: Three piece end fitting having deforming fingers for use with corrugated tubing
Inventor: TREICHEL STEVEN A
IPC: F16L37/12
Filed: 2000-05-15
Abstract: An end fitting for connecting to the end of corrugated tubing (400) comprising a first body (100), a second body (200) and a locating sleeve.  The first body (100) has a central conduit, and a plurality of fingers (11) positioned radially about the body's centerline, separated from an adjacent finger (11) by a space.  The second body has a central conduit and a conical finger deflection surface about the body's centerline.  In use the corrugated tubing (400) passes through the first body  (100) and centres on the location sleeve positioned in the second body (200).  The first body (100) is screwed in against the deflection surface of the second body (200) forcing the fingers (11) into the corrugations of the tubing (400) sealing and retaining the tubing (400) in position.
Patent NZ-509803-A (NZ)
Title: Treatment of fibromyalgia with ubiquinone 10 and succinic acid
Inventor: SNEED PAUL A
IPC: A61K31/194
Filed: 2001-02-08
Abstract: Described is a pharmaceutical composition comprising ubiquinone 10 and succinic acid and the use of ubiquinone 10 and succinic acid in the manufacture of a medicament for the treatment of fibromyalgia.
Patent NZ-511057-A (NZ)
Title: Jointing chamber assembly with opening formed between walls and base, and sealing plate over opening
Inventor: LENNOX-ROBERTSON ROGER
IPC: B65D1/22
Filed: 2001-04-09
Abstract: Walls 10 are assembled to base 11 to form an opening over which a sealing plate (not shown) is fixed.
Patent NZ-513616-A (NZ)
Title: Multipanel floor system panel connector in form of inverted "T" shape with seal attached to connector
Inventor: NELSON THOMAS J
IPC: E04F15/022
Filed: 2001-08-17
Abstract: A connector is disclosed for assembling and sealing laminate flooring panels which are separate from the connector, the connector comprising: a base; an extension attached to the base and at least one ridge extending vertically from the base, and having a mating member for mating with a flooring panel; and a seal attached to a member selected from the base the ridge and the extension. The construction is such that when two floor panels are connected together the resultant visible flooring surface consists of only the top wear surface of the panels. Addition to 511336
Patent NZ-517471-A (NZ)
Title: Mesoprogestins for the treatment and prevention of benign hormone dependent gynecological disorders
Inventor: CHWALISZ KRISTOF
IPC: A61P15/04
Filed: 2000-08-31
Abstract: A mesoprogestin selected from J867, J912, J900, J914 and J1042 is used in the manufacture of a medicament for treating or preventing benign hormone dependent gynecological disorders.
Patent NZ-517832-A (NZ)
Title: Process for preparing food contact grade polyethylene terephthalate resin from waste pet containers
Inventor: KOSIOR EDWARD
IPC: B29C48/04
Filed: 2000-09-18
Abstract: A process for preparing food contact grade PET from a waste stream containing PET and non-PET materials is disclosed. The process involves the steps of sorting at least some of the non PET materials from the waste stream, followed by dividing the PET containers into flakes of preferable maximum size approximately 10mm, followed by washing the flakes in a hot aqueous medium containing alkaline materials and surfactants, preferably non-ionic, to remove particulate and absorbed contaminants from the surfaces of the flakes. This step is followed by de-watering and then drying the flakes to a moisture content of 0.1 % w/w maximum, and more preferably 0.01 % w/w maximum. The next step involves removing absorbed contaminants and moisture by heating and vigorously mixing the flakes under vacuum, preferably 1-10 millibar, more preferably 2-7 millibar and at a temperature less than the melting point of PET, preferably in the range 170-220 DEG C for at least 30 minutes, preferably at least 60 minutes. The final step involves melting the flakes in a screw extruder equipped for vacuum processing and extruding the molten material to form strands that are pelletised.
Patent NZ-519378-A (NZ)
Title: Adamantane derivatives
Inventor: CAFFREY MOYA
IPC: A61P37/00
Filed: 2000-12-12
Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (II).
Patent NZ-521735-A (NZ)
Title: Peptide-based compounds, their use as targeting vectors that bind to receptors associated with antiogenesis such as integrin receptors
Inventor: CUTHBERTSON ALAN
IPC: A61K38/08
Filed: 2001-04-06
Abstract: The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise a targeting vector which binds to receptors associated with integrin receptors.
Patent NZ-523703-A (NZ)
Title: Process for the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives
Inventor: KOOISTRA JACOB HERMANUS MATTHE
IPC: C07B61/00
Filed: 2001-07-12
Abstract: A process for the preparation of a 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivative of formula 1 where: - X stands for a leaving group, and - R1, R2 and R3 are each independently represent an alkyl group with 1-3 carbon atoms, starting from a compound of formula 2. The process uses an acetalization agent in the presence of an acid catalyst. With regard to formula 2, X is defined as above.
Patent NZ-524568-A (NZ)
Title: Stabilization of solid drug formulations
Inventor: SPIREAS SPIRIDON
IPC: A61K9/48
Filed: 2001-09-26
Abstract: Disclosed is a drug dosage form prepared by compression techniques comprising: a substantially non-volatile, pharmaceutically acceptable oil, and a compound susceptible to moisture-induced degradation treated with the substantially non-volatile, pharmaceutically acceptable oil to substantially waterproof the compound susceptible to moisture-induced degradation; the drug dosage form prepared by: (a) dispersing the compound susceptible to moisture-induced degradation in the substantially non-volatile, pharmaceutically acceptable oil; and (b) compacting the compound susceptible to moisture-induced degradation into dosage forms using compression pressures of up to 5000 psi/g. Further disclosed is the use of a compound susceptible to moisture-induced degradation and a substantially non-volatile, pharmaceutically acceptable oil in the manufacture of a dosage form using compression pressures of up to 5000 psi/g.
Patent NZ-528236-A (NZ)
Title: Apparatus for diverting, revectoring and accelerating a flowing gas mass
Inventor: HOPKINS ROBERT SEABROOKE
IPC: F03D1/04
Filed: 2002-02-15
Abstract: An apparatus for diverting, revectoring and accelerating a mass of gas, for example, a rapidly moving air mass traversing the landscape, wherein the apparatus comprises first and second spaced-apart upstanding walls, the first wall being disposed relative to the second wall such that the lower terminus of the first wall is disposed above the lower terminus of the second wall, thereby forming an entry inlet for high velocity air mass to pass between the walls and exit at the other end; the walls are disposed in a convergent rotation in the direction of the exit outlet of the apparatus and further, the upper terminus of the second wall being positioned relative to the upper terminus of the first wall such that an air mass flowing through the space between the first and second walls will exit the apparatus at an accelerated flow rate relative to the entry flow rate and with a vector divergent form the flow vector at the entry inlet and the walls being disposed.
Patent NZ-533266-A (NZ)
Title: Acetylene derivatives having MGLUR 5 antagonistic activity
Inventor: GASPARINI FABRIZIO
IPC: C07D209/36
Filed: 2002-12-03
Abstract: A compound of formula 1 is described wherein: m is 0 or 1; n is 0 or 1; A is hydroxy, X is hydrogen, and Y is hydrogen; or A forms a single bond with X or with Y; R0 is hydrogen, (C1-4)alkyl, (C1-4)alkoxy, trifluoromethyl, halogen, cyano, nitro, -COOR1 wherein R1 is (C1-4)alkyl or -COR2 wherein R2 is hydrogen or (C1-4)alkyl; and R is -COR3, -COOR3, -CONR4R5 or -SO2R6, wherein R3 is (C1-4)alkyl, (C3-7)cycloalkyl or optionally substituted phenyl, 2-pyridyl or 2-thienyl, R4 and R5, independently, are hydrogen or (C1-4) alkyl and R6 is (C1-4)alkyl, (C3-7)cycloalkyl or optionally substituted phenyl, R' is hydrogen or (C1-4)alkyl and R" is hydrogen or(C1-4)alkyl, or R' and R" together form a group -CH2-(CH2)p- wherein p is 0, 1 or 2 in which case one of n and p is different from 0; With the proviso that R0 is different from hydrogen, trimethyl and methoxy when m is 1, n is 0, A is hydroxy, X and Y are both hydrogen, R is COOEt and R' and R'' together from a group -(CH2)2-. The compounds are useful in the treatment of disorders associated with irregularities of glutamatergic signal transmission and of nervous system disorders mediated full or in part by mGluR5.
Patent NZ-540000-A (NZ)
Title: Implants with tacrolimus
Inventor: WNENDT STEPHAN
IPC: A61F2/06
Filed: 2002-02-18
Abstract: Disclosed is an implant for intracavernous or intravascular application, preferably for the treatment or prophylaxis of coronary or peripheral vascular constriction or occlusion, in particular constriction and stenoses or restenoses, preferably for the prophylaxis of restenoses, comprising FK506 in a chemically covalently or non-covalently bonded or physically fixed form, a method for production and use thereof.
Patent NZ-540456-A (NZ)
Title: Pyrrolopyrimidine derivatives for treating hyperproliferative disorders such as cancer
Inventor: ARCARI JOEL THOMAS
IPC: C07D487/04
Filed: 2003-12-08
Abstract: Pyrrolopyrimidine derivatives of formula (I), pharmaceutically acceptable salt, prodrug and hydrates thereof, that are useful in the treatment of hyperproliferative diseases, such as cancers, in mammals are disclosed, wherein Q, A, L, R1, R2 and R3 are as defined in the specification. The disclosure also relates to pharmaceutical compositions containing the compounds of formula (I) and the use thereof in the treatment of hyperproliferative diseases including abnormal cell growth such as cancer in mammals, especially humans.