baber/WOPTO huggingface dataset:
Patent EP-4161579-A1 (EP)
Inventor: CHAUVIERRE CÉDRIC
IPC: A61P7/02
Filed: 2021-06-08
Abstract: There is a dire need for innovative nanomedicine-based solutions for safe and efficient thrombolysis with a non-toxic, biocompatible, and biodegradable thrombus-targeted carrier. In the present invention, polysaccharide hydrogel submicroparticles with remarkable biocompatibility were elaborated by the inverse miniemulsion / crosslinking method. They were functionalized with a fucoidan which has a nanomolar affinity for the P-selectin overexpressed on activated platelets and endothelial cells in vascular diseases. Surprisingly, the inventors show that rtPA (i.e. Alteplase) can be loaded onto the submicroparticles by adsorption, and its amidolytic and fibrinolytic activities were maintained in vitro and in vivo. Thrombus targeting potential of these particles was validated in microfluidic assay under arterial and venous blood shear rates on recombinant P-selectin and activated platelet aggregates. The thrombolytic efficacy of the nanomedicine-based product was tested in a murine model of acute ischemic stroke, revealing faster middle cerebral artery recanalization and reduction in the brain infarct volume and blood-brain barrier permeability post-stroke, evidenced by laser speckle contrast imaging and MRI. Collectively, this proof of concept study demonstrates the potential of these particles for the precise treatment of acute thrombotic events.
Patent EP-4091063-A1 (EP)
Inventor: BARVE RAKESH
IPC: G06F16/00
Filed: 2021-01-19
Abstract: A method and system is provided for mapping a term to a vector representation in a semantic space. Provided techniques allow for efficient and accurate determination of vector representations for query terms that are terms of emerging interest or are otherwise not included in a set of terms for which vector representations are pre-calculated.
Patent EP-4098570-A1 (EP)
Inventor: KOMATSU KUNIO
IPC: B67B3/26
Filed: 2021-01-29
Abstract: The purpose of the present invention is to provide a detection device that detects the occurrence of an event (so-called "double capping") in which two caps are disposed on one container. To that end, the detection device (10, 10A) of the present invention has two types of sensors provided on a production line (100) for a commercial product in which an opening (1A) of a container (1) is sealed with a cap (2), said sensors being a proximity sensor (3) along a path where the container (1) moves and a sensor (4: for example, a transmission sensor) equipped with a transmitter (4A), which is inside the same path, and a receiver (4B) . An area detected by the sensors (3, 4) is an area where the cap (2) is not present in a normal state (a state in which double capping has not occurred), but where a subsequent cap (2-1) is present if two caps (2) in a row have been attached to one container (1) .
Patent EP-4096586-A1 (EP)
Inventor: ORESCHNICK MARK
IPC: A61F5/01
Filed: 2021-01-29
Abstract: An upper torso augmentation device in which a moment of an arm assembly is tunable by the movement of one or more movable masses. The upper torso augmentation device including an upper arm assembly pivotably coupled to a shoulder assembly, the upper arm assembly including an assisted force mechanism configured to aid in counteracting an effect of gravity upon the upper arm assembly and any payload carried thereby, the assisted force mechanism comprises one or more movable masses configured to move relative to a distal end of the upper arm assembly, thereby affecting a change in a moment of the upper arm assembly.
Patent EP-4178674-A1 (EP)
Inventor: PAYTON LORI
IPC: A61K39/00
Filed: 2021-07-08
Abstract: L'invention concerne des méthodes de traitement clinique de l'hémoglobinurie paroxystique nocturne (PNH) chez des patients pédiatriques à l'aide d'un anticorps anti-C5, ou d'un fragment de liaison à l'antigène de celui-ci.
Patent EP-4089688-A1 (EP)
Title: Medical imaging-based method and device for diagnostic information processing, and storage medium
Inventor: SHI LEI
IPC: G06T7/00
Filed: 2021-02-05
Abstract: Disclosed in the present invention are a diagnostic information processing method and apparatus based on a medical image, and a storage medium, to achieve disease grading based on a medical image. The method includes: acquiring a first lung medical image of a object; acquiring image parameters of an affected part in the first lung medical image; and determining, according to the image parameters of the affected part, a disease grade of lungs of the examined object corresponding to information of the first lung medical image. By using the solution provided by the present invention, the image parameters of the affected part in the first lung medical image can be acquired, and then the disease grade of the lungs of the examined object corresponding to the information of the first lung medical image can be determined according to the image parameters of the affected part, so that a disease can be graded based on a medical image.
Patent EP-4105242-A1 (EP)
Inventor: NISHIMURA KIMIAKI
IPC: A61F13/53
Filed: 2021-02-12
Abstract: It is an object to provide a water-absorbing resin that while maintaining water-absorbing resin physical properties such as water absorption performance, has a sufficiently reduced odor produced during swelling. The object is attained by causing the water-absorbing resin to be a water-absorbing resin which is a surface-crosslinked water-absorbing resin, the water-absorbing resin having a volatile component concentration of 3.5 ppm or less as measured when the water-absorbing resin is caused to stand still for 15 minutes under a condition that the water-absorbing resin has a swelling capacity of 1.0-fold.
Patent EP-4107536-A1 (EP)
Inventor: JAVEY ALI
IPC: G01R31/36
Filed: 2021-02-19
Abstract: A battery management system configured to detect impending failure of a lithium-ion battery cell includes a sensor array microchip. The microchip includes a plurality of silicon chemical-sensitive field effect transistors (CS-FETs) configured to detect multiple distinct gases vented by the lithium-ion battery cell. The battery management system also includes a cell monitoring unit (CMU) configured to receive from at least one of the CS-FETs data indicative of a detected amount of gas vented by the lithium-ion battery cell. The CMU is also configured to compare the data indicative of the detected amount of the vented gas to a predetermined threshold amount of the subject vented gas programmed into the CMU. The CMU is further configured to trigger a signal indicative of impending failure of the lithium-ion battery cell when the detected amount of the vented gas exceeds the predetermined threshold amount of the subject vented gas.
Patent EP-3920318-A1 (EP)
Inventor: MORIMURA WATARU
IPC: H01M10/052
Filed: 2021-02-19
Abstract: An embodiment of the present invention provides a separator for a non-aqueous secondary battery containing: a porous layer that is provided on only one side of the porous substrate, and that contains a resin having at least one bonding group selected from the group consisting of an amide bond, an imide bond, and a sulfonyl bond, in which, in the porous substrate, an absolute value of a difference between a temperature of an endothermic peak observed at from 120°C to 145°C in a temperature raising process 1, and a temperature of an endothermic peak observed at from 120°C to 145°C in a temperature raising process 2, is 1.50°C or higher in DSC measurement when the temperature raising process 1 of continuously raising the temperature from 30°C to 200°C at a temperature change rate of 5°C/min in a nitrogen atmosphere, and the temperature raising process 2 of lowering the temperature from 200°C to 30°C and raising the temperature from 30°C to 200°C, are performed.
Patent EP-4190034-A1 (EP)
Title: Access to second network
Inventor: TALEBI FARD PEYMAN
IPC: H04W48/16
Filed: 2021-08-09
Abstract: A base station receives, from a first network, a configuration message. The configuration message comprises an indication that the first network supports onboarding for a second network. The configuration message comprises an identifier of the second network. The base station sends, to a mobility management function of the first network, an onboarding request for onboarding of a wireless device to the second network.
Patent EP-4102212-A1 (EP)
Inventor: SUZUKI YOSHIHISA
IPC: G01N27/00
Filed: 2021-02-03
Abstract: The gas measurement device includes a catalyst member connected to a power source applying voltage or current, performing a reaction of a first gas and a second gas contained in a mixed gas contacted with the catalyst member to generate a third gas, and exhibiting a catalytic action in which the reaction changes in response to temperature, and a gas sensor configured to detect gas molecules contacted with the catalyst member.
Patent EP-4169208-A1 (EP)
Inventor: DAVIES JACK OWEN
IPC: H04L9/32
Filed: 2021-08-31
Abstract: A comprising, by target computer equipment of a target party: obtaining a cryptographic key derived from a response generated by PUF module comprising a physically unclonable function, PUF, the response having been generated by the PUF module based on the PUF in response to a corresponding challenge input to the PUF module, wherein key information comprising the cryptographic key or a corresponding public key is also made available to a verifying party; from an issuing party, receiving a computation request specifying the computation to be performed; in response to the computation request, performing the computation in order to generate a computation result; signing a message comprising the computation result with the cryptographic key; and making the signed message available to the verifying party by sending the signed message to be recorded on a blockchain.
Patent EP-4209119-A1 (EP)
Inventor: WONG CHU FAI CHU LEUN
IPC: H05B47/115
Filed: 2021-09-02
Abstract: A system (21) is configured to obtain a control history of one or more lighting devices (35,36) of a networked lighting system and detect a regularly occurring sequence of manual light control actions (91.92) based on the control history. The control history describes light control actions and the sequence of manual light control actions comprises a light control action associated with a location. The system is further configured to determine a location for a presence sensor or light switch based on the location associated with the light control action such that the network lighting system is able to trigger one or more of the manual light control actions at an appropriate moment when the presence sensor or light switch is placed at the determined location and output the determined location to a user to facilitate the installation of the presence sensor or light switch in the networked lighting system.
Patent EP-4214424-A1 (EP)
Title: Bloc de matériau de friction, en particulier pour équiper des plaquettes de frein et plaquette de frein associée et procédé
Inventor: SIN XICOLA AGUSTIN
IPC: F16D69/02
Filed: 2021-09-17
Abstract: La présente invention concerne un bloc ou une couche de frottement constitué(e) d'un matériau de frottement sans amiante, le matériau de frottement comprenant, en tant que matériaux de composition de celui-ci, des fibres inorganiques et/ou organiques et/ou métalliques, au moins un liant, au moins un modificateur de frottement ou un lubrifiant et au moins une charge ou un abrasif, le matériau de frottement sans amiante contenant également, en tant que matériau ou additif de composition supplémentaire, une cire hydrophobe, de préférence présente de 0,5 % à 5 % en volume, le bloc ou la couche de matériau de frottement sans amiante présentant une hydrophobicité, définie comme étant le temps d'absorption à l'intérieur du matériau de frottement d'une goutte de liquide formée par 20 +/- 5 pl d'eau distillée, de plus de 60 minutes de telle sorte que la force pour détacher le bloc ou la couche de frottement d'une surface métallique à laquelle il ou elle a été amené(e) à frotter par adhérence de manière électrochimique, soit inférieure à 15 Nw.
Patent EP-4127342-A1 (EP)
Inventor: DOMBOWSKY MICHAEL ANTHONY
IPC: E04G21/00
Filed: 2021-03-26
Abstract: Systems and methods of constructing a single-storey building utilizing a plurality of prefabricated insulated panels, each of the plurality of prefabricated insulated panels comprising a first cementitious layer, a second cementitious layer, and an insulative core, wherein the insulative core is disposed between the first and second cementitious layers. The systems and methods comprise constructing a building foundation and constructing the single-storey building on said foundation, the building comprising an exterior wall supported by at least said building foundation using a first plurality of the prefabricated insulated panels, the first plurality of panels forming the exterior wall disposed on an outer perimeter of the building and a roof supported by at least said exterior wall using a second plurality of the prefabricated insulated panels, the second plurality of panels forming the roof enclosing a top of the single-storey building.
Patent EP-4213899-A1 (EP)
Inventor: WOLFSTEIN ANDRE
IPC: A61L24/00
Filed: 2021-09-10
Abstract: The invention relates to a tissue adhesive (14) for use in a treatment method in which an ophthalmological implant (12) is implanted in a human or animal patient and the ophthalmological implant (12) is connected, at least partially in an integrally bonded manner, to eye tissue of the patient by means of the tissue adhesive (14). The invention also relates to an ophthalmological implantation system (10) comprising an ophthalmological implant (12) for implantation in a human or animal eye and to a tissue adhesive (14) by means of which the ophthalmological implant (12) is connectable, at least partially in an integrally bonded manner, to eye tissue of the patient.
Patent EP-4243652-A1 (EP)
Inventor: ILL BERNHARD
IPC: A47B88/447
Filed: 2021-09-20
Abstract: Eine Ausziehführung zum Ausziehen eines ausziehbaren Möbelteils (5) aus einem Möbelkorpus (4) weist eine erste Schiene (1) und eine zweite Schiene (2) auf, wobei das Ausziehen der ersten Schiene (1) durch Anschlägen eines Anschlagelements (13) der ersten Schiene (1) an einem Auszieh-Anschlag (12) der zweiten Schiene (2) begrenzt ist. An der zweiten Schiene (2) ist ein Sicherungsteil (14) beweglich gelagert, welches zwischen einer Freigabestellung, in welcher zum vollständigen Herausnehmen der ersten Schiene (1) die erste Schiene (1) gegenüber der zweiten Schiene (2) so weit verschwenkbar ist, dass das Anschlagelement (13) außer Eingriff mit dem Auszieh-Anschlag (12) bringbar ist, und einer Sperrsteilung verstellbar ist. Das Sicherungsteil (14) ist über einen von der Sperrstellung bis in die Freigabestellung sich erstreckenden Verschiebeweg in eine Verschieberichtung (15), die mit der der Ausziehrichtung (6) entgegengesetzten Richtung einen Winkel (16) von weniger als 20° einschließt, verschiebbar gelagert. Die Verschwenkbarkeit der ersten Schiene (1) nimmt über den Verschiebeweg des Sicherungsteils (14) kontinuierlich zu.
Patent EP-4118757-A1 (EP)
Title: Controlling antenna beam generation to compensate for motion of a high-altitude platform
Inventor: ANANTH SHARATH
IPC: H01Q3/26
Filed: 2021-03-18
Abstract: A method and an antenna system are provided for a high-altitude platform (HAP) (102, 200, 400, 603) configured to move in a pattern (604) in the stratosphere to provide coverage to a region of interest and compensate for HAP movement relative to the region of interest. HAP movement is monitored (905). When it is determined that the HAP has moved relative to the region of interest (910) and, based on the relative movement, a first one of a plurality of antennas in the HAP is no longer able to cover a selected portion of the region of interest (915), an antenna array switching circuit in the HAP is used to adjust beams transmitted by the antennas by switching to a second one of the plurality of antennas to cover the selected portion of the region of interest, such that the communication services provided to the region of interest are not interrupted due to the movement of the HAP (920).
Patent EP-4134091-A1 (EP)
Inventor: PARK BYUNG YOUNG
IPC: A61P9/10
Filed: 2021-04-07
Abstract: The present invention relates to a fraction extract of Melissa officinalis leaves, and a novel pharmaceutical composition and a food composition that include same.
Patent EP-4134174-A1 (EP)
Title: Data collection method, data collection system, data collection device, data provision method, and computer program
Inventor: MATSUMURA SHOTA
IPC: B07C5/342
Filed: 2021-02-01
Abstract: Provided are a data collection method, a data collection system, a data collection device, a data provision method, and a computer program for autonomously collecting data in stages in classification. This data collection method includes a process in which: identification codes for identifying products are acquired from a classifier that includes a reader for reading the identification codes, the classifier transporting the products to different classification locations on the basis of the identification codes and carrying out classification, the identification codes having been read by the reader; image data of the products identified by the acquired identification codes is acquired from a camera attached so as to photograph the products transported by the classifier; and the acquired image data is stored in association with the acquired identification codes.
Patent EP-4138845-A1 (EP)
Title: Methods of detecting and treating cancers characterized by loss of mir15 and mir16 expression
Inventor: CROCE CARLO M
IPC: A61K39/395
Filed: 2021-04-21
Abstract: Provided herein are, in various embodiments, methods of predicting a likelihood of a subject developing an acute myeloid leukemia (AML) or blast crisis (BC), methods of detecting a subject having AML or BC cells susceptible to treatment with a B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) inhibitor, a B-cell lymphoma 2 (Bcl -2) inhibitor and/or a Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) inhibitor, methods of stratifying subjects having Myelodysplastic syndrome (MDS) or chronic phase chronic myeloid leukemia (CML), and methods of preparing a sample that is useful for performing the disclosed methods. The present invention also provides methods of treating a subject having a leukemia (e.g., MDS AML or CML) with a therapy that increases the expression or activity of miR-15a, miR-15b, miR-16-1 and/or miR-16-2 gene product, reduces the expression or activity of a target of said gene product, or a combination thereof.
Patent EP-4146279-A1 (EP)
Inventor: BJÖRKHOLM LARS
IPC: A61K31/465
Filed: 2021-05-07
Abstract: The specification discloses compositions for use in the oral or nasal cavity comprising a biologically active agent, a matrix forming agent comprising alginate and suitable salts thereof, a filling agent and at least one antioxidant that is an effective complex binder. The compositions can further comprise additional excipients such as preservatives, taste or flavour enhancers, pH adjusters, plasticizers and sweeteners. The specification also discloses methods of producing the compositions.
Patent EP-4149934-A1 (EP)
Title: Crystalline forms and formulations of a vcp/p97 inhibitor
Inventor: ZHOU HAN-JIE
IPC: C07D403/04
Filed: 2021-05-10
Abstract: Described herein are crystalline forms of 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide, and pharmaceutically acceptable salts and solvates thereof. Also described herein are pharmaceutical formulations of 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide, and pharmaceutically acceptable salts and solvates thereof.
Patent EP-4247885-A1 (EP)
Inventor: WEHRMANN ROLF
IPC: C08K3/22
Filed: 2021-11-18
Abstract: Described are titanium dioxide-containing, polycarbonate-based thermoplastic compositions that contain metal oxide-containing mica in very low amounts and are suitable for reflectors. The addition of mica results in improved reflectance values as compared to the same mixtures without mica component.
Patent EP-4251463-A1 (EP)
Inventor: CONTI MAURO
IPC: B60L53/62
Filed: 2021-11-16
Abstract: The present invention is related to a method for identification of a supply equipment (120) adapted to charge an electric vehicle (130). This method includes: − an initialization phase, in which the device (200) is operationally connected to the supply equipment (120) and to the electric vehicle (130) through interfacing means (220); − a storage step, where the device (200) stores through storage means (230) first values, that is the first values being predefined and related to the supply equipment (120); − an acquisition step, wherein the device (200) acquires through interfacing means (220) second values, said second values being representative of said supply equipment (120) during the process of charging of said electric vehicle (130); − a comparison step, wherein the device (200) compares through processing means (235), the first values and the second values; − a generation step, wherein the device (200) generates through processing means (235) at least one verification signal in case the first values are not comparable with the second values, according to the comparison step; − an output step, wherein the device (200) outputs via interfacing means (220) at least one verification signal in the case if at least one verification signal has been generated.
Patent EP-4240147-A1 (EP)
Inventor: FERNANDES PAUL G
IPC: A01K73/02
Filed: 2021-11-09
Abstract: A gate mechanism (20) is adapted for mounting within the extension (4) of a trawl net (1), the gate mechanism comprising a turbine (47/147/247) for powering rotation of the gate mechanism as it is dragged through the water within the trawl net.
Patent EP-4158128-A1 (EP)
Inventor: JOHANSSON PATRICK
IPC: E04C2/16
Filed: 2021-05-30
Abstract: La présente invention concerne un montant (10) de construction permettant de former une ossature pour monter des panneaux muraux, comprenant une première partie (12) de rebord et une seconde partie (14) de rebord et une partie âme (16) reliant mutuellement les parties de rebord. Les parties de rebord comprennent un élément (18, 20) oblong plan en fibres de bois, et la partie âme comprend un élément (22) formant plaque à base de polymère et/ou de fibres cellulosiques comprenant une première (24) et une seconde (26) ligne de faiblesse rectiligne, lesquelles lignes de faiblesse sont parallèles et le long desquelles l'élément formant plaque est pliable pour permettre le pliage du montant de construction d'une position de rangement rétractée à une position de montage déployée.
Patent EP-4161968-A1 (EP)
Inventor: NELSON DELIA JANE
IPC: C07K16/28
Filed: 2021-06-04
Abstract: La présente invention concerne d'une manière générale l'identification de certains anticorps anti-CD40 agonistes. L'invention concerne également de nouveaux anticorps agonistes et leur utilisation en thérapie.
Patent EP-3989346-A1 (EP)
Inventor: SHIN JUNG-IL
IPC: H01M50/116
Filed: 2021-03-16
Abstract: Provided is a modular battery pack for an Energy Storage System (ESS), especially a home ESS. The battery pack according to the present disclosure includes a casing, at least two battery cells, and a system including a cartridge in which the battery cell is received and a lead jig, wherein the cartridge is configured to be opened and closed to attach/detach the battery cell, and the lead jig is configured to be mounted/demounted on/from a lead of the battery cell, and when the battery cell is received in the cartridge and stacked in a thicknesswise direction and the lead jig is mounted on the lead of the battery cell, an electrical connection is established between the battery cells without welding the leads of the battery cells.