baber/WOPTO huggingface dataset:
Patent CZ-298711-B6 (CZ)
Title: Pharmaceutical compositions activating LT-beta receptor for treating or reducing the advancement, severity or effects of neoplasia, method for selecting LT-beta receptor activating agent and antibodies against LT-beta receptor
Inventor: BROWNING JEFFREY L
IPC: C12N5/20
Filed: 1996-01-26
Abstract: The present invention relates to pharmaceutical compositions useful for activating LT-beta receptor signaling, which in turn elicits potent anti-proliferative effects on tumor cells. More particularly, this invention relates to lymphotoxin heteromeric complexes formed between lymphotoxin-alpha and multiple subunits of lymphotoxin-beta , which induce cytotoxic effects on tumor cells in the presence of lymphotoxin-beta receptor activating agents. Also within the scope of this invention are antibodies directed against the lymphotoxin-beta receptor, which act as lymphotoxin-beta receptor activating agents alone or in combination with other lymphotoxin-beta receptor activating agents either in the presence or in absence of lymphotoxin-alpha/beta complexes. A screening method for selecting such antibodies is provided. This invention also relates to compositions and methods using cross-linked anti-lymphotoxin-beta receptor antibodies either alone or in the presence of other lymphotoxin-beta receptor activating agents to potentiate tumor cell cytotoxicity.
Patent CZ-285158-B6 (CZ)
Inventor: BURRI JAKOB
IPC: F42B14/02
Filed: 1997-09-08
Abstract: Charakteristickým znakem vodícího kroužku /7/ je jeho snadné a spolehlivé spojení s pouzdrem /2/ střely. Vodící kroužek /7/ je spojovacími můstky procházejícími otvory /9/ v pouzdru /2/ střely, pevně spojen s těsnicím tělesem /10/, které je umístěno na zadní straně střely, uvnitř pouzdra /2/ střely. Vodicí kroužek /7/ se vyrobí společně s těsnicím tělesem /10/ jednou operací výrobního postupu, a to vstříknutím umělé hmoty do pouzdra /2/ střely jeho otevřenou zadní stranou.ŕ
Patent CZ-285757-B6 (CZ)
Title: decontamination process of solid materials of mineral origin
Inventor: SEVCIK VLADIMIR RNDR CSC
IPC: B09C1/10
Filed: 1997-11-26
Abstract: The decontamination of solid materials of mineral origin by aerobes is performed in the presence of anionic or non-ionic tensides, applied in a mass ratio of 0.001 to 0.1 parts per 100 parts of mineral material, in the form of 0.001 to 2 % by weight of aqueous solution. The optimum conditions for the development of the soil aerobes can be induced so that the contaminated material, dampened with the aqueous tenside solution, is mixed with undeveloped compost in the logarithmic development phase of the soil aerobes, at a mass ratio of compost to contaminated material of 1:2 to 1:20.
Patent SK-283843-B6 (SK)
Title: Novel synthesis of myo-inositol phosphates
Inventor: BITTMAN ROBERT
IPC: C07F9/08
Filed: 1998-02-04
Abstract: Provided herein are novel syntheses of the phosphate-based inositol derivatives 1-(O)-[(+)-menthoxycarbonyl]-6-(O)-benzyl- 2,3:4,5-di-(O)-isopropylidene-(myo)-inositol (D4P), D-myo-inositol-1,4,5-triphosphate (D-IP3), 6-(O)-benzyl-2,3:4,5- di-(O)-isopropylidene-(myo)-inositol-(H)-phosphonate (3-HP) and L-myo-inositol-1,4,5-triphosphate (L-IP3). These syntheses employ fewer column chromatography steps for the isolation of intermediates than do prior art syntheses, and hence, are more convenient, economical and efficient than are the previously known synthetic methods.
Patent SK-283255-B6 (SK)
Title: Stable pharmaceutical composition, preparation method and use
Inventor: DURR MANFRED
IPC: A61K31/425
Filed: 1995-04-24
Abstract: Stable pharmaceutical composition having a high concentration of an active taxoid class ingredient such as docetaxel or docetaxel derivatives. The pharmaceutical composition is characterised in that it comprises a therapeutic taxoid class agent such as docetaxel or docetaxel derivatives, one or more unsaturated phospholipids and a small quantity of one or more negative phospholipids.
Patent SK-278778-B6 (SK)
Title: The electrode
Inventor: STEININGER KARL-HEINZ
IPC: C25B11/048
Filed: 1989-03-13
Abstract: The electrode described in this patent being able to be polarised in electrolyte consists of the high conductive electric wire (1), while the suitable material is metal or carbon, of the internal layer (2), which is in the intermediate contact with the electric wire (1), and this layer consists plastic material with electrical conductivity and this material may contain filling represented by graphite or black carbon with a high resistance again the electrolyte acting, and on the external side (3) being contacted with electrolyte and consisting of plastic material with electrochemical activity, while this material is able to change its own structure, as a result of the above mentioned electrolyte acting. Round the wire (1), there are arranged two layers (2, 3) at least or they are placed on this wire directly overlapping each other, while the electric high conductive wire (1) surrounding by the internal layer (2) is close and this layer is created based on non polar plastic material represented by polyethylene or polypropylene or by the mixture of them, and the external layer (3) created based on the polar plastic materials which can be represented by ethylvinylacetate, hard or soft polyvinylchloride, terpolymer of acrylonitrile, butadiene and styrene, chlorinated polyethylene, nitrile resin, resin based on styrene or butadiene, halogenated elastomer or the mixture of the above mentioned materials.
Patent SK-278951-B6 (SK)
Title: Process of deacidification and desodoration of the plant oils
Inventor: CHRBET JAN
IPC: C11B3/12
Filed: 1995-12-27
Abstract: Plant oil is supplied to a vacuum evaporator, after its filtration and / or sedimentation or slime removal and bleaching has been completed and after having heated to the temperature of 185 up to 255 Celsius degrees, it is supplied to a non heated short way gravity evaporator and removal of acids together with deodorization is provided subsequently, while distillation of tin falling film without drossing, at the temperature 181 up to 250 Celisus degrees and at the pressure 201 up to 1000 Pa, is applied for these purposes. Based on this principle, free fat acids and compounds causing an unfavourable savour and smell are removed, while a maximum content of natural substances worth from biological point of view is kept, however durability, biological and physiological values and sensoric properties are improved.
Patent SK-277958-B6 (SK)
Title: Algicidal aget
Inventor: KRALOVA KATARINA
IPC: A01N43/46
Filed: 1992-07-01
Abstract: Algicidal agent contains as effective matter the compound with general formula I, in which or means alkoxyl with 3 to 8 atoms of carbon in meta-or para-position of benzene core. Compound by invention act algicidal by concentrations 1,25.10/exp-5/ mol.dm/exp-3/ and higher.
Patent CZ-304505-B6 (CZ)
Title: Device for forming structural part using high internal pressure
Inventor: GARCIA GOMEZ RAFAEL
IPC: B21D26/041
Filed: 2006-12-01
Abstract: The invented device for forming by a high internal pressure is intended for forming a structural component (37) in a form tool (28) having a lower die (26) and an upper die (27). The upper die (27) die can be coupled via at least one hydraulic cylinder and piston unit (30) to perform a limited relative travel, with a slide (35) of a mechanical press (2) having a constant pressing path, wherein the chamber of said hydraulic cylinder and piston unit (30) can be connected through a hydraulic medium line with the internal space of the structural component (37). The press (2) having a pressure regulation unit, consisting of a piston-cylinder and spring unit (1), is provided with another device for additional processing operations.
Patent CZ-302934-B6 (CZ)
Title: Soil stabilizing agent exhibiting fertilizing activity and process for preparing thereof
Inventor: BOSANSKA MONIKA
IPC: C05G3/80
Filed: 2010-08-09
Abstract: The present invention relates to a soil stabilizing agent exhibiting fertilizing activity comprising as an active substance a combination of 1 to 99 percent by volume mineral component being represented by alginite, and 1 to 99 percent by volume biological compost obtained by aerobic fermentation of waste sludge from the production of penicillin and/or thymidine and/or threonine and/or other amino acids, optionally along with pre-composted mycelium without residual penicillin and mixed in sawdust.
Patent CZ-305044-B6 (CZ)
Title: Apparatus for fluidized bed combustion of solid fuels or suspensions
Inventor: POHOŘEL MICHAEL
IPC: F23C1/00
Filed: 2013-08-20
Abstract: In the present invention, there is disclosed an apparatus for fluidized bed combustion of solid fuels or suspensions, comprising a mixer of gaseous/fluidization/combustion media a preheater of the combustion media disposed behind the gaseous/fluidization/combustion medium mixer or incorporated therein. A mixture of the combustion media is then supplied through the fluidization/combustion medium inlet (5) via at least one electric preheater (8, 9) to a distributor (6) with a pressure gauge (17) disposed therebelow and a pressure gauge (18) disposed thereabove. An inlet of a solid fuel or a suspension and/or a fluidized bed secondary material, along with the pneumatic transportation arrangement (3) and separated from the region above the distributor (6) by a countercurrent cooler (4), is disposed above the distributor (6). A reactor comprising boiling, bubbling or spouted fluidized bed (28) is arranged above the solid fuel or suspension inlet. In the reactor lid, there are arranged an inlet of a thermometer (14) passing through the entire structure up to the distributor, and optionally an inlet of a pressure gauge (19) inlet, as well as one outlet (16) for analyses of composition and amount of products. A hot cyclone (20) is arranged in the space after the above-fluidized bed layer area (29). A sampling track (30) with a point for thermometers (23) and sampling points (22) for on-line and off-line analyzes of gas is arranged after the hot cyclone (20). A countercurrent water cooler (24) is arranged after the sampling track (30) and a condenser (25) and a chimney (27) are arranged after the countercurrent water cooler (24) wherein a point (26) for on-line gas analysis is arranged between the condenser (25) and the chimney (27).
Patent CZ-306446-B6 (CZ)
Title: A working machine for adjusting and shaping the sides of the railway superstructure and the sides of the railway ditches and adjustment of railway bedding
Inventor: ŠTEFEK ALAN
IPC: E01B27/10
Filed: 2015-07-08
Abstract: The working machine for adjusting and shaping the sides of the railway superstructure and the sides of the railway ditches and adjustment of railway bedding comprises the main frame (101) positioned on two undercarriages (102) and (103), where on the main frame (101), there is located at least one cab (104). Above the main frame (101), there is positioned, by means of the slew ring (107), the boom (108), whose opposite end is provided with the bucket wheel (111) by means of the joint (110), enabling tilting of the axis of rotation of the wheel (111) in two planes for the work of the wheel (111) on both sides of the axis of the track, perpendicular to the rails, parallel with the rails or at any angle between these limit positions, where the axis of rotation of the wheel (111) is always horizontal. The boom (108) is firmly connected to the discharge conveyor (109) and, on the main frame (101), there is pivotably mounted another conveyor (112) for pouring the excavated material on a car or on the slope of the railway bedding, while, on both sides of the main frame (101), there are positioned packer ploughs (106) for forming the adjoining flat surfaces and slopes.
Patent CZ-306738-B6 (CZ)
Title: A production strain of the alga of Monoraphidium sp. for the production of oils containing polyunsaturated fatty acids, the way of production of these oils and the use of this production strain for industrial production of these oils
Inventor: ŘEZANKA TOMÁŠ
IPC: C12P7/64
Filed: 2016-06-07
Abstract: The production strain of the alga of Monoraphidium sp., deposited in the Collection of Autotrophic Organisms of the Botanical Institute of the Academy of Sciences of the Czech Republic, Třeboň, Dukelská 135, under the accession number CCALA 1094: Monoraphidium sp., Nedbalová 2009/1, is exploitable as a source for the industrial production of oils having a high content of polyunsaturated fatty acids, in particular hexadecatetraenoic acid and stearidonic acid for human or animal food supplements or for the use in other applications. The invention also describes the method of producing oils having a high content of polyunsaturated fatty acids in a production strain, consisting in its exposure to low culture temperatures.
Patent SK-284596-B6 (SK)
Title: Process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6- chloro-9-H-purine-9-yl)-2-cyclopentenyl-1-methanol or its salts
Inventor: BRIEDEN WALTER
IPC: C07C233/23
Filed: 1998-11-23
Abstract: There is disclosed a process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6-chloro-9-H-purine-9-yl)-2-cyclopentenyl- 1-methanol or its salts of the formulas (I), (II) is carried out by reacting (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2- cyclopentene D- or L-hydrogentartrate with N-(2-amino-4,6- dichloropyrimidin-5-yl)formamide to give (1S,4R)- or (1R,4S)-4-[(2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino]-2- cyclopentenyl-1-methanol and then cyclized to give the end compounds.
Patent SK-283022-B6 (SK)
Title: Compositions comprising Cetrorelix acetate for the treatment of female infertility and gonadal protection
Inventor: ENGEL JURGEN
IPC: A61K38/10
Filed: 1994-02-18
Abstract: Disclosed is a use of cetrorelix acetate for production of a medicament for treatment of female infertility and gonadal protection.
Patent CZ-297093-B6 (CZ)
Title: Process for isolating and purifying HMG-CoA reductase inhibitors
Inventor: PFLAUM ZLATKO
IPC: A61K31/22
Filed: 1999-02-17
Abstract: In the present invention, there is described a process for the isolation and purification of HMG-CoA reductase inhibitors from a mycelium biomass, which process comprises: clarifying a mycelium broth and concentrating the clarified broth to a lower volume; acidifying the concentrate to a pH value in the range of 4.5 to 7.5, followed by extracting a HMG-CoA reductase inhibitor with ethyl acetate; crystallization of the HMG-CoA reductase inhibitor from a water-miscible or water-soluble organic solvent; and crystallization of the HMG-CoA reductase inhibitor from an organic solvent having limited miscibility or solubility with water. The crystallization steps may also be reverse. The concept of a combination of the specified crystallization steps can also be used for the purification of crude HMG-CoA reductase inhibitors.
Patent CZ-298293-B6 (CZ)
Title: Medicament for treating sleeping disorders
Inventor: CHEETHAM SHARON CRAWFORD
IPC: A61K/
Filed: 2000-03-17
Abstract: In the present invention, there is disclosed the use of a compound of the general formula I, including enantiomers and pharmaceutically acceptable salts thereof in which Ri1 and Ri2 represent independently on each other hydrogen or methyl, optionally in conjunction with a pharmaceutically acceptable diluent or carrier, for the preparation of a medicament intended for treating sleeping disorders including sleep apnoea and snoring.
Patent CZ-307144-B6 (CZ)
Title: An indolylmaleimide compound, a method of its preparation, its use as a medication and a pharmaceutical composition containing this compound
Inventor: ALBERT RAINER
IPC: C07D521/00
Filed: 2001-11-05
Abstract: Indolylmaleimide derivatives comprising either a substituted phenyl, naphthyl, tetrahydronaphthyl, quinazolinyl, quinolyl, isoquinolyl or pyrimidinyl residue have interesting pharmaceutical properties, e.g. in the treatment and/or prevention of T-cell mediated acute or chronic inflammatory diseases or disorders, autoimmune diseases, graft rejection or cancer.
Patent PL-211243-B6 (PL)
Inventor: BOSCH WILLIAM H
IPC: A61K9/16
Filed: 2002-12-09
Abstract: Niniejszy wynalazek dotyczy nowej kompozycji farmaceutycznej związku
Patent SK-288294-B6 (SK)
Title: Method for producing L-amino acids
Inventor: LIVSHITS VITALIY ARKADYEVICH
IPC: C12R1/19
Filed: 1999-12-22
Abstract: The invention relates to a method for producing L-amino acids, especially L-homoserine and L-threonine, and branched chain amino acids, especially L-valine and L-leucine, with ahigher yield, by using bacteria belonging to the genus Escherichia. The bacterium used in the method according to the invention is abacterium, which has the ability to produce the amino acid and in which rhtC gene coding for a protein having an activity of making a bacterium having the protein L-threonine- resistant is enhanced. Preferably it is the bacterium in which rhtB gene coding for a protein having an activity of making a bacterium having the protein L-homoserine-resistant is further enhanced, said bacterium being cultivated in a culture medium to produce and accumulate the amino acid in the medium, and the amino acid is recovered from the medium.
Patent BR-PI0111373-B8 (BR)
Title: recipiente de reação de amostra de sangue de múltiplas finalidades para uso em um sistema de hematologia baseado em citometria de fluxo, e sistema de citometria de fluxo
Inventor: HAROLD C FLYNN JR
IPC: G01N21/05
Filed: 2001-05-24
Abstract: "sistemas de coleta de luz sem lente e de citometria de fluxo para a classificação e contagem de células biológicas em uma amostra recipiente de reação de amostra de sangue de múltiplas finalidades para uso na citometria de fluxo, e, método para analisar uma amostra de sangue ou uma amostra derivada do sangue". o sistema da presente invenção é um citômetro de fluxo que inclui um sistema ótico sem lente para controlar o caminho da luz emitida a partir de uma fonte de luz de laser (30). a fonte de luz de laser é uma fonte de luz de laser de diodo padrão que emite um feixe fino. a forma do feixe de luz de laser é bem adaptado para a detecção de luz dispersa. além disso, a confiabilidade do sistema é ainda realçada pelo uso de uma série de fotodetectores (48) que não inclui nenhuma parte móvel. a série de fotodetector é tal que a luz dispersa é detectável, e estes dados coletados fornecem uma análise hematológica completa. finalmente, o sistema usa um sistema único de tubos reagentes consumíveis (60) que atuam como câmara de reação, câmaras de mistura e câmaras de refugo para as análises da amostra sangüínea.
Patent EP-1512631-B8 (EP)
Inventor: SCHLOESSER WERNER
IPC: B65B1/12
Filed: 2004-08-24
Granted: 2008-09-03
Abstract: The filling device includes an issuing funnel (12), filling tube (13), a conveyor screw (14) in the filling tube and connected to a rotary drive motor, and a height adjustable closer (16) at the lower end of the filling tube. The rotary drive motor, conveyor screw and closer are an adjustable in height relative to the filling tube.
Patent EP-1831981-B8 (EP)
Inventor: ALTEMARK JENS
IPC: H02J3/18
Filed: 2005-12-15
Granted: 2012-04-04
Abstract: A wind farm includes a plurality of wind energy installations which generate electrical energy to be output to a power supply system and a wind farm master for controlling the wind energy installations. Each wind energy installation includes a generator which is driven by a rotor, and the wind farm master includes a power control device having a plurality of loops. This plurality of loops includes a fast loop that includes a controller which acts on a first group of the wind energy installations and a slow loop that includes a controller which acts on a second group of the wind energy installations, the fast controller having a substantially higher dynamic than the slow controller.
Patent EP-1844266-B8 (EP)
Inventor: LIVCHAK ANDREY V
IPC: F24F1/0067
Filed: 2006-01-06
Granted: 2009-02-18
Abstract: Displacement ventilation systems are generally poor performers when it comes to heating. The instant patent application discusses devices and systems for improving heating performance while retaining the benefits of displacement ventilation without wholesale co-location of independent space conditioning systems.
Patent EP-1892547-B8 (EP)
Inventor: SATO RYUICHIRO
IPC: G02B6/255
Filed: 2006-06-05
Granted: 2012-02-29
Abstract: A heating reinforcing device for carrying out reinforcement quickly and efficiently in an adequate heating time, a fusion connecting device including the heating reinforcing device, and a fusion connecting method. A heating unit of the heating reinforcing device is used for heating and shrinking the reinforcing sleeve so placed to cover a fusion connecting section and has heaters turned on/off by independent switches and capable of individually heating reinforcing selves at different timings or a heater turned on/off by a switch. The device may comprise a detecting unit for detecting whether or not a reinforcing sleeve is placed on the heater and turning on/off a switch.
Patent EP-1937310-B8 (EP)
Inventor: FIUME LUIGI
IPC: A61K47/48
Filed: 2006-09-19
Granted: 2011-07-13
Abstract: The present invention refers to the use of a conjugate of doxorubicin with lactosaminated human albumin for the preparation of a pharmaceutical composition useful in the treatment of hepatocellular carcinomas (HCCs) which do not express the asialoglycoprotein receptor (ASGP-R). The conjugate which was previously prepared and studied only for the treatment of HCCs expressing the ASGP-R, has now been shown to possess the potentiality of a beneficial use also in the treatment of the HCCs which do not have the receptor. Therefore, compositions containing the conjugate could be administered for treatment of all HCCs, without the need of a preliminary tumor biopsy to demonstrate the presence or the absence of the receptor.
Patent EP-1005566-B8 (EP)
Inventor: CARLSSON THOMAS
IPC: A61B5/1473
Filed: 1998-07-08
Granted: 2007-12-26
Abstract: The invention relates to a system for continuous monitoring of analytes in a biological fluid, the system having increased life by virtue of inherent regeneration of sensors employed. An embodiment of the invention includes a biosensor, a sampling device for providing a sample of the biological fluid, device(s) for passing a flow of a background fluid through the flow passage at selectable flow rates, device(s) for injecting the sample into the flow of background fluid, and device(s) for increasing the flow rate of the combined flow. An embodiment of the invention provides device(s) for achieving a washing action at the signal generating portion.
Patent BR-PI0605465-B8 (BR)
Title: sistema para diagnóstico de parasitos intestinais por análise computadorizada de imagens
Inventor: Alexandre Xavier Falcão
IPC: G01N33/483
Filed: 2006-11-30
Abstract: sistema para diagnóstico de parasitos intestinais por análise computadorizada de imagens a presente invenção consiste de um sistema para diagnóstico de parasitos intestinais de humanos e animais por análise computadorizada de imagens microscópicas obtidas de amostras fecais. o sistema utiliza equipamentos disponíveis no mercado, um kit parasitológico apropriado, e técnicas computacionais e parasitológicas, especialmente desenvolvidas para resolver o problema. as vantagens do sistema proposto em relação aos procedimentos adotados atualmente nos laboratórios de análises clínicas são: maior produtividade; maior sensibilidade diagnóstica; menor despesa com mão-de-obra; redução de utensílios e espaço físico no laboratório de parasitologia; rapidez, praticidade e segurança diagnóstica; diminuição do risco de contato e contaminação do profissional de laboratório; descarte de material analisado em recipiente apropriado para material tóxico, seguindo normas de biossegurança; inovação na liberação dos resultados através de imagens; resgate da credibilidade no diagnóstico de parasitoses intestinais por parte da classe médica, evitando o uso empírico, indiscriminado e ineficaz de medicamentos.