baber/WOPTO huggingface dataset:
Patent CA-2995695-A1 (CA)
Inventor: RAINY JEFFREY
IPC: G06N3/08
Filed: 2018-02-20
Abstract: Systems and methods for use in training a convolutional neural network (CNN) for image and video transformations. The CNN is trained by adding noise to training data set images, transforming both the noisy image and the source image, and then determining the difference between the transformed noisy image and the transformed source image. The CNN is further trained by using an object classifier network and noting the node activation levels within that classifier network when transformed images (from the CNN) are classified. By iteratively adjusting the CNN to minimize a combined loss function that includes the differences between the node activation levels for the transformed references images and when transformed source are classified and the differences between the transformed noisy image and the transformed source image, the artistic style being transferred is maintained in the transformed images.
Patent CA-2997703-A1 (CA)
Inventor: NEWBOLD TAMARA
IPC: C07D471/04
Filed: 2015-03-05
Abstract: The present disclosure provides a crystalline form of grapiprant selected from the group consisting of Form X, Form X2, Form X3, Form F, Form K, Form L, Form M, and Form N. Also provided is a pharmaceutical composition, the composition comprising at least one crystalline form of grapiprant, and at least one pharmaceutically acceptable excipient, wherein the crystalline form of grapiprant is selected from the group consisting of Form X, Form X2, Form X3, Form F, Form K, Form L, Form M, and Form N. Other aspects of the disclosure provide a process for preparing a substantially pure crystalline Form A of grapiprant.  The process comprises contacting grapiprant at ambient temperature with a solvent comprising dichloromethane and acetone to form a saturated or a near saturated solution.  Crystals of the substantially pure crystalline Form A of grapiprant are formed.
Patent CA-2997893-A1 (CA)
Title: Procede et dispositif de commande de recyclage des gaz d'echappement
Inventor: KOBARA TETSUYA
IPC: F02D23/00
Filed: 2015-09-07
Abstract: La présente invention concerne un procédé de commande de recyclage des gaz d'échappement pour un moteur à combustion interne pourvu : d'un turbocompresseur de suralimentation ; d'un passage de recyclage des gaz d'échappement qui permet à un passage de gaz d'échappement de communiquer avec un passage d'admission en amont d'un compresseur du turbocompresseur de suralimentation ; d'une soupape de régulation de la quantité de recyclage des gaz d'échappement disposée dans le passage de recyclage des gaz d'échappement ; d'une soupape de production de pression différentielle disposée en amont d'une partie dans laquelle le gaz frais dans le passage d'admission se mélange au gaz d'échappement ; et d'une unité de commande qui commande le degré d'ouverture de la soupape de régulation de la quantité de recyclage des gaz d'échappement et le degré d'ouverture de la soupape de production de pression différentielle, l'unité de commande effectuant une commande coordonnée du degré d'ouverture de la soupape de régulation de la quantité de recyclage des gaz d'échappement et du degré d'ouverture de la soupape de production de pression différentielle, puis modifie un rapport de recyclage des gaz d'échappement jusqu'à un rapport cible de recyclage des gaz d'échappement à l'aide d'un taux de changement qui supprime une combustion anormale dans le moteur à combustion interne.
Patent CA-2998284-A1 (CA)
Title: Cryoprobe
Inventor: SNYDER LLOYD M
IPC: A61B18/02
Filed: 2018-03-19
Abstract: A cryoprobe is used during surgery in a human body to remove unwanted tissue. The cryoprobe includes a first gas supply line and a second gas supply line for delivering a supply of cryogenic gas from at least adjacent a proximal end to at least adjacent a distal end of the cryoprobe. The cryoprobe further includes a first gas return line and a second gas return line for returning the supply of cryogenic gas from at least adjacent the distal end to at least adjacent the proximal end of the cryoprobe. At least a portion of the first gas supply line is received in the first gas return line. A transition portion having at least one internal cavity and an aperture from the at least one internal cavity to an exterior portion of the transition portion is also included in the cryoprobe. The transition portion is provided to facilitate at least the transfer of the cryogenic gas from the second gas return line to the first gas return line, so that the cryogenic gas can flow adjacent the first gas supply line on its way to the proximal end of the cryoprobe.
Patent CA-3001831-A1 (CA)
Title: Compositions, packaged pharmaceuticals, and methods of using hedgehog pathway modulators for the sensitization of resistant tumors
Inventor: BHAGWANDIN VIKASH J
IPC: C07D405/14
Filed: 2016-10-12
Abstract: Compositions, packaged pharmaceuticals, and methods of treatment by the sensitization of resistant tumors are provided. The compositions comprise a combination of a hedgehog pathway modulator, such as itraconazole, and a chemotherapeutic agent. Tumor cells in mammalian subjects treated with the hedgehog pathway modulator are sensitized to the effects of the chemotherapeutic agent, thus increasing the therapeutic index of the agent and reducing toxicity to the subject.
Patent CA-3002871-A1 (CA)
Inventor: COLLINS JONATHAN M
IPC: C07K1/06
Filed: 2016-10-21
Abstract: La présente invention concerne un procédé amélioré de déprotection dans la synthèse peptidique en phase solide. En particulier la composition de déprotection est ajoutée à concentration élevée et sous un faible volume au mélange de la solution de couplage, de la chaîne peptidique en croissance, et de n'importe quel acide activé en excès provenant du précédent cycle de couplage, et sans aucune étape de drainage entre l'étape de couplage du cycle précédent et l'ajout de la composition de déprotection pour les cycles consécutifs. Ensuite, la pression ambiante dans le récipient est réduite par une aspiration sous vide afin d'éliminer la composition de déprotection sans aucune étape de drainage et sans nuire autrement aux matériaux restants dans le récipient ou provoquer de problèmes aux étapes ultérieures dans le cycle de SPPS.
Patent CA-3004951-A1 (CA)
Inventor: MCKENNA ELIZABETH
IPC: A61K35/74
Filed: 2016-11-10
Abstract: Disclosed herein are compositions and methods for regulating redox status and/of reducing oxidative stress in a subject, the methods and compositions comprising TLR agonists comprising bacterial lysates and/or lysate fractions. Also disclosed are compositions and methods comprising bacterial lysates and/or lysate fractions formulated or administered in combination with one or more other therapeutic or pharmaceutical agents.
Patent CA-3007477-A1 (CA)
Title: Evaluation de la surveillance du volume respiratoire pour detecter la compromission respiratoire avant l'oxymetrie pulsee et eliminer les fausses alertes de desaturation
Inventor: FREEMAN JENNY E
IPC: A61B5/02
Filed: 2016-12-15
Abstract: La présente invention concerne des systèmes et des procédés d'optimisation de la surveillance continue et réaliste du volume respiratoire permettant une évaluation rapide du patient.
Patent CA-3008375-A1 (CA)
Inventor: WORTHING RICHARD ROY
IPC: B23P6/04
Filed: 2018-06-14
Abstract: An automated welding system includes a mounting platform configured to receive an object, a welding tool, an imaging device configured to acquire at least one image associated with the object, and a controller. The controller is configured to receive the at least one acquired image, analyze at least one pixel in the at least one acquired image, identify, based upon the analyzing, an area to be welded in the at least one acquired image, wherein the area to be welded includes a defect, and generate, based upon the identifying, control instructions for controlling at least one of the mounting platform and the welding tool to weld the area to be welded.
Patent CA-3009073-A1 (CA)
Inventor: KURZ VOLKER L S
IPC: B81B7/02
Filed: 2016-12-29
Abstract: Cette invention concerne des appareils et des procédés destinés à être utilisés le barbotage, la convection et le déplacement par commande optique d'un flux fluidique de sorte à fournir une force motrice dans des dispositifs microfluidiques. Des modalités de déplacement alternatives sont utiles pour déloger et déplacer sélectivement des micro-objets, comprenant des cellules biologiques, à partir de divers emplacements dans l'enceinte d'un dispositif microfluidique.
Patent CA-3009185-A1 (CA)
Inventor: SABRIPOUR SHERVIN
IPC: H04N5/232
Filed: 2016-12-06
Abstract: A method (450) and apparatus for imaging a scene (101). The method (450) includes receiving a plurality of images (404) of the scene (101) from a plurality of first source devices. The method (450) also includes receiving a first metadata identifying a location and a field-of-view (203) of each of the plurality of first source devices. The method (450) also includes receiving a second metadata identifying a location and a field-of-view (203) of each of one or more available image source devices (200). The method (450) also includes identifying overlapping portions of the plurality of images (404). The method (450) also includes stitching the plurality of images (404) together to form a combined image (418) of the scene (101) based on the overlapping portions of the plurality of images (404). The method (450) also includes identifying a missing portion of the combined image (418) of the scene (101) and responsive to identifying the missing portion, performing one or more actions to fill a part of the missing portion.
Patent CA-3011185-A1 (CA)
Title: Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
Inventor: BOECKL ANDREW JOHN
IPC: A61K9/14
Filed: 2017-01-20
Abstract: A method of manufacturing a flowable and dispersible powder includes solubilizing a lipophilic substance in a terpene to form a mixture and treating the mixture to form a nanoemulsion dispersed in an aqueous solution. The aqueous solution includes at least one functional excipient. The nanoemulsion is then spray dried, thereby evaporating first the aqueous portion and then the terpene to form a dry powder formed from solid particles comprising the lipophilic substance.
Patent CA-3012301-A1 (CA)
Inventor: DOYA YO
IPC: C07C227/42
Filed: 2017-01-11
Abstract: [Problème] Rendre la taille et la forme de particules obtenues uniformes. L'invention concerne un mode au moyen duquel le coût d'énergie n'est pas augmenté. [Solution] La présente invention concerne un procédé de production de particules pour lequel un contact est établi entre une pluralité de substances dissemblables A et B, ledit procédé comprenant les étapes suivantes : amener un liquide à s'écouler depuis la partie d'extrémité d'un côté d'un processeur 10 le long de la surface périphérique interne du processeur 10 ; générer, par l'intermédiaire de ce flux entrant de liquide, un flux rotatif vers la partie d'extrémité de l'autre côté du processeur 10 ; la disposition à l'intérieur du processeur 10 d'une aube d'assistance à l'écoulement de liquide 12 qui peut tourner autour de l'axe central du processeur 10, et amener l'aube d'assistance à l'écoulement 12 à tourner ; et injecter les substances mises en contact A et B devant entrer en contact à l'intérieur du processeur 10, amener le liquide de contact à s'écouler hors de la partie d'extrémité de l'autre côté du processeur 10, et générer des particules dans ce liquide mis en contact.
Patent CA-3016556-A1 (CA)
Inventor: BREWER DAVID N
IPC: B01J14/00
Filed: 2017-02-28
Abstract: Dilatometer systems for measuring characteristics of material samples are disclosed. In one embodiment, a dilatometer system includes a reactor adapted to receive the test sample, a density trap in fluid communication with the reactor, a first fluid selectively filling the reactor and a portion of the density trap, and a second fluid selectively filling a portion of the density trap. The first fluid and the second fluid are immiscible with one another and selectively form an immiscible fluid boundary in the density trap. The dilatometer system further includes a heater that selectively heats the first fluid.
Patent CA-3017119-A1 (CA)
Title: Connecteurs de fibres optiques a ferrule avec equilibrage de retraction de ferrule
Inventor: COMPTON BRANDON DUVALL
IPC: G02B6/38
Filed: 2017-03-01
Abstract: La présente invention concerne des connecteurs de fibres optiques à ferrule présentant une caractéristique d'équilibrage de rétraction de ferrule pour préserver les performances optiques. Le connecteur de fibre optique comprend un ensemble connecteur, un ensemble manchon de connecteur et un élément élastique d'équilibrage. L'ensemble connecteur comprend une ferrule et un élément élastique pour solliciter la ferrule vers l'avant et l'ensemble manchon de connecteur comprend un boîtier et un manchon de ferrule, l'ensemble connecteur étant au moins partiellement disposé dans le passage du boîtier et la ferrule de l'ensemble connecteur étant au moins partiellement disposée dans le manchon de ferrule. L'élément élastique d'équilibrage sollicite le boîtier vers une position vers l'avant avec un élément élastique de sollicitation ayant une force élastique prédéterminée qui est supérieure à la force de frottement nécessaire pour le déplacement de la ferrule à l'intérieur du manchon de ferrule.
Patent CA-3018091-A1 (CA)
Inventor: CAVALERI FRANCO
IPC: A61P3/06
Filed: 2018-03-08
Abstract: Methods for increasing LDL receptor levels in a plurality of cells are disclosed. For example, the methods include providing to the cells a curcumin composition that is at least 15% curcumin II or at least 5% curcumin III, in order to increase LDL receptor levels. In addition, compositions for increasing LDL receptor levels in a plurality of cells are disclosed, which include a curcumin composition consisting of at least 15% curcumin II or at least 5% curcumin III (or combinations of such curcuminoids), along with a pharmaceutically-acceptable solvent, filler, or carrier. Still further, methods for decreasing MSK1 levels in a plurality of cells are disclosed, which involve administering a curcumin Ill- enriched composition to the cells.
Patent CA-3018194-A1 (CA)
Title: Technique pour tuer des agents pathogenes in vivo
Inventor: HARRISON NOAH JAMES
IPC: C12N15/85
Filed: 2017-04-11
Abstract: La présente invention concerne et revendique un procédé amélioré pour tuer des microbes pathogènes chez un patient. Le procédé amélioré comprend la transduction de cellules eucaryotes du patient avec un premier vecteur viral qui ne transfectera pas les microbes pathogènes. Le premier vecteur viral est déficient en réplication et code dans son génome recombinant un premier gène de résistance antimicrobien et un promoteur. Un médicament antimicrobien est administré au patient.
Patent CA-3019829-A1 (CA)
Inventor: SRINIVASAN SUDARSAN
IPC: B65D83/02
Filed: 2017-03-31
Abstract: An attachable needle assembly (102) for use on a medication delivery pen (104), the needle assembly (102) comprising a housing (110) enclosing a hub (106) having a communication needle (108) configured to engage the medication delivery pen (104) and pierce a reservoir septum of the medication delivery pen (104), a communication septum (172, 176) of the needle assembly (102) defining a septum chamber (180, 182) that is in fluid communication with the communication needle (108), a plurality of needles (118) disposed in the communication septum (172, 176), a follower ring (130) that determines which needle (124) of the plurality of needles (118) is to be selected, and a snap ring (136) that exposes the selected needle (124) and moves the selected needle (124) in fluid communication with the septum chamber (180, 182), wherein when the housing (110) is in a first position, the plurality of needles (118) is not exposed, and when the housing (110) is in a second position, the selected needle (124) is in fluid communication with the septum chamber (180, 182) and exposed for medicament delivery.
Patent CA-3019841-A1 (CA)
Title: Methods and compositions for the prevention and treatment of surgical adhesions
Inventor: TSAI JONATHAN
IPC: A61K45/00
Filed: 2017-05-01
Abstract: Aspects of the present disclosure include methods of treating a subject to reduce adhesion formation, the method comprising administering to a subject in need of thereof an agent that that targets adhesion-formation by injured mesothelial cells. The agent can act at a variety of checkpoints in the development of adhesions by injured mesothelial cells, including: targeting the injured mesothelial cells for destruction, recruiting inflammatory macrophages to the site of adhesion, preventing neutrophil recruitment to the site of adhesion, and/or inhibiting the expression or activity of a gene product whose expression is induced in the injured mesothelial cells. Compositions and kits for performing the methods are also provided.
Patent CA-3022641-A1 (CA)
Title: Prosthetic heart valves with elastic support structures and related methods
Inventor: BEITH JASON G
IPC: A61F2/24
Filed: 2017-10-26
Abstract: Prosthetic heart valves having elastic leaflets and an elastic support structure are described. The support structure can exhibit a precursory transition from the closed position to the open position. The support structures can exhibit a sinusoidal movement profile at a base edge during the precursory transition.
Patent CA-3023998-A1 (CA)
Title: Pin retention for conveyor modules
Inventor: RICHARDSON ANDREW
IPC: B65G17/40
Filed: 2017-05-23
Abstract: A conveyor module (10) includes a module body (12) with a pair of first link ends (14) extending in a first direction of travel and a second link end (16) extending in a second direction of travel opposite the first direction. Each of the first and second link ends (14, 16) has a transverse opening (15, 17) therethrough. At least one of the first link ends (14) has a first mating portion (30). A pin (20) is configured to be received in the first transverse openings (15) of the module body (12). The pin (20) has a shaft (22) and a lever (28) affixed at a first end (24) of the shaft (22). The lever (28) has a second mating portion configured to be rotatably coupled with the first mating portion (30) of the module body (12), thereby preventing transverse movement of the shaft (22).
Patent CA-3025359-A1 (CA)
Title: Systemes, dispositifs et procedes pour generer de maniere dynamique des destinations, des heures et des itineraires de livraison
Inventor: MCHALE BRIAN GERARD
IPC: H04L12/26
Filed: 2017-05-31
Abstract: L'invention concerne des méthodologies, des systèmes et des supports lisibles par ordinateur pour générer des itinéraires pour reprogrammer une livraison d'objets. Des données publiques relatives à l'emplacement actuel d'un utilisateur, à l'emplacement actuel d'un objet à livrer et aux futurs plans de déplacement de l'utilisateur sont obtenues. Des données personnelles sont également obtenues, y compris des préférences de reprogrammation personnalisables et des futurs plans de déplacement associés à l'utilisateur. Une destination de reprogrammation est calculée pour la reprogrammation de la livraison de l'objet à l'utilisateur d'une destination de livraison actuelle à la destination de reprogrammation sur la base des données publiques et des données personnelles associées à l'utilisateur. Une heure de reprogrammation et un itinéraire de reprogrammation sont également calculés, en fonction en partie des données publiques et des données personnelles associées à l'utilisateur. Une notification de la destination de reprogrammation et de l'heure de reprogrammation est ensuite transmise à un dispositif électronique associé à l'utilisateur.
Patent CA-3025829-A1 (CA)
Inventor: BURKHOLZ JONATHAN KARL
IPC: A61B5/06
Filed: 2017-05-25
Abstract: Systems, methods and devices are described including a medical device subassembly including a magnetic feature. Systems include such a catheter adapter subassembly (1012, 112, 12, 212, 312, 512, 612, 712) or needle subassembly (1112, 114, 14, 214, 314, 514, 614) or guidewire introducer subassembly (1216) and a wire (1050) including a magnetic feature, and relative movement of the catheter adapter subassembly (1012, 112, 12, 212, 312, 512, 612, 712) or needle subassembly (1112, 114, 14, 214, 314, 514, 614) or guidewire introducer subassembly (1216) and the wire (1050) can be determined using a magnetometer.
Patent CA-3027251-A1 (CA)
Title: An apparatus and method for semi-permeable membrane based blood filtration
Inventor: VOWLES GERALD J
IPC: A61M1/36
Filed: 2018-12-13
Abstract: An apparatus and method for semi-permeable membrane based blood filtration featuring controlled filtrate to non-filtrate separation ratio, self-regulating pressure intensification and energy recovery means and wherein basic embodiments can function without the need for valves or any other control means. These capabilities are provided for by a cooperating, positive displacement pump and motor set based apparatus wherein the greater volumetric displacement of an upstream hydraulic pump cannot be fully taken up by a lesser volumetric displacement downstream hydraulic motor as they operate synchronously within the same series circuit. This causes pressure intensification within the fluid circuit located between the pump and motor such that a volume of fluid essentially equal to the pump to motor volumetric displacement differential is compelled to flow out of the pressurized circuit by passing through or permeating the semi-permeable membrane located within it.
Patent CA-3028975-A1 (CA)
Title: Methods for diagnosis and treatment of autoimmune diseases
Inventor: ROWE MICHAEL WILLIAM
IPC: G01N33/574
Filed: 2017-06-20
Abstract: Provided herein are methods, assays and devices for the detection and diagnosis of autoimmune diseases, including systemic lupus erythematosus. The methods, assays and devices provided herein analyzes binding patterns of peripheral-blood antibodies on peptide array that correlates well with current systemic lupus erythematosus clinical assessment standards.
Patent CA-3029313-A1 (CA)
Inventor: SITARAM ANESHKUMAR DINESHCHANDRA
IPC: A61K8/44
Filed: 2017-06-27
Abstract: The disclosed technology relates to a method of decreasing or preventing signs of ageing of décolleté skin and optionally the face and/or neck skin comprising topically applying to the skin a composition comprising a cosmetically acceptable medium, a vitamin C, or derivative thereof, and compound having two or more hydroxyl groups, wherein the compound has a molar mass of at least 150 g/mol and increases transglutaminase K expression in epidermal keratinocytes.
Patent CA-3030285-A1 (CA)
Title: Boulon deformable resistant a la corrosion
Inventor: MA LUMIN
IPC: E21D21/00
Filed: 2017-07-11
Abstract: Un boulon de mine comprend un corps allongé ayant une première extrémité et une seconde extrémité positionnée à l'opposé de la première extrémité, le corps allongé ayant une première section filetée, une seconde section filetée, et une section non filetée positionnée entre la première section filetée et la seconde section filetée. La section non filetée est configurée pour se déformer sous l'effet du chargement lorsque le boulon de mine est installé avec du coulis dans un trou de forage.