baber/WOPTO huggingface dataset:
Patent NO-960769-D0 (NO)
Inventor: MESENS JEAN LOUIS
IPC: A61K31/506
Filed: 1996-02-26
Abstract: PCT No. PCT/EP94/02764 Sec. 371 Date Jan. 26, 1996 Sec. 102(e) Date Jan. 26, 1996 PCT Filed Aug. 19, 1994 PCT Pub. No. WO95/05815 PCT Pub. Date Mar. 2, 1995The present invention relates to the iontophoretic delivery to a patient, more in particular to a migraine patient, of a compound of formula (I) as shown hereinunder. The invention also relates to a device for the iontophoretic delivery of a compound of formula (I), as well as to a composition containing a compound of formula (I), which can be applied in a device for iontophoretic delivery. Said compounds are benzopyranalkylaminoalkyl substituted guanidines having the formula    <IMAGE>  (I)  the pharmaceutically acceptable acid addition salts thereof, and the stereochemically isomeric forms thereof, wherein R1 is hydrogen or C1-6alkyl; R2 is hydrogen, C1-6alkyl, C3-6alkenyl or C3-6alkynyl; R3 is hydrogen or C1-6alkyl; or R2 and R3 taken together form a bivalent radical of formula -(CH2)m- wherein m is 4 or 5; or R1 and R2 taken together form a bivalent radical of formula -CH=CH- or of formula -(CH2)n-, wherein n is 2, 3 or 4; or R3 may represent a bond when R1 and R2 taken together form a bivalent radical of formula -CH=CH-CH=; R4 and R5 each independently are hydrogen or C1-6alkyl; Alk1 is a bivalent C1-3alkanediyl radical; Alk2 is a bivalent C2-15alkanediyl radical; and R6 and R7 each independently are hydrogen, halo, C1-6alkyl, C3-6alkenyl, C3-6alkynyl, hydroxy, C1-6alkyloxy or cyano.
Patent NO-961381-D0 (NO)
Inventor: BAUMSTARK ROLAND
IPC: C09D157/12
Filed: 1996-04-03
Abstract: PCT No. PCT/EP94/03224 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 27, 1994 PCT Pub. No. WO95/09896 PCT Pub. Date Apr. 13, 1995Aqueous polymer compositions which contain a polymer having ureido groups and a polyaldehyde compound are suitable for the production of coatings having high adhesion to substrate and having high cohesion.
Patent NO-962595-D0 (NO)
Inventor: KLOMP ULFERT CORNELIS
IPC: C09K8/52
Filed: 1996-06-19
Abstract: A method is provided for inhibiting the formation of hydrates in streams containing low-boiling hydrocarbons and water. The method includes adding to the stream a component of the formula:   <IMAGE>   wherein R1, R2, and R3 are independently chosen from the group consisting of normal and branched alkyls having at least 4 carbon atoms, and X is N-R4, wherein R4 is selected from the group consisting of hydrogen and organic substituents and Y- is an anion. The amount added is an amount that is effective to inhibit formation of hydrates in the mixture at conduit temperatures and pressures. The preferred R4 is an alkyl or alkenyl having from eight to twenty carbons, and the preferred R1, R2, and R3 are alkyls having four to six carbon atoms.
Patent NO-981262-D0 (NO)
Inventor: PARVIAINEN SEPPO
IPC: B23B41/00
Filed: 1998-03-20
Abstract: A method for drilling holes into a mantle of a cylinder of a paper machine while the cylinder is in its site of operation in the paper machine. The holes are drilled into the cylinder mantle by a drilling device having drill bits and which is transferred after each drilling cycle to the next drilling position. When drilling the holes, the device is supported on cylinders placed adjacent to and above the cylinder to be machined and/or on the cylinder to be machined by fastening supports of the device. Before the drilling is started, the device is locked in its position by locking fastening supports in a desired position and, the holes are drilled into the cylinder placed underneath from the top toward the bottom. The device includes drill bits, a frame construction, a drive gear for transferring and rotating the drill bits during the drilling, fastening supports for supporting the device in its place in the drilling position against the cylinders placed above and adjacent to the cylinder to be machined and/or against the cylinder to be machined, and an actuator for locking the device in its place in the drilling position.
Patent NO-984786-D0 (NO)
Inventor: BERGMANN FRED HARALD
IPC: B01J8/10
Filed: 1998-10-14
Abstract: A prepolymerisation reactor (1) for the liquid phase polymerisation of olefin monomers in the presence of a catalyst, comprising: a substantially cylindrical non-partitioned reactor chamber having a circumferential, longitudinal reactor wall, a first end wall and a second end wall (2, 3), the ratio between the length and diameter of said reactor chamber being from 4:1 to 15:1; a shaft (4) positioned in the reactor chamber, which shaft is provided with impellers (6); a monomer feed inlet opening (26); a catalyst feed inlet opening (30); an outlet opening; and at least one baffle (7) positioned substantially longitudinally within said reactor chamber.
Patent NO-985742-D0 (NO)
Inventor: SIMS JOHN E
IPC: C12N15/54
Filed: 1998-12-08
Abstract: Purified and isolated IL-1/TNF- alpha -activated kinase (ITAK), nucleic acids encoding ITAK, processes for production of recombinant forms of ITAK, pharmaceutical compositions containing ITAK, and use of ITAK in therapies and in various assays, including assays to detect antagonists and agonists of ITAK are provided.
Patent NO-990088-D0 (NO)
Inventor: LEVY RUTH
IPC: A61P25/16
Filed: 1999-01-08
Abstract: Pharmaceutical compositions for the treatment of a neurological disorder of neurotrauma or for improving memory in a patient comprising a therapeutically effective amount of S-(-)-N-proparygl-1-aminoindan or a pharmaceutically acceptable salt thereof as active ingredient, and a pharmaceutically active carrier. The pharmaceutical compositions are adapted, in particular for treating a neurological hypoxia or anoxia, neurodegenerative diseases. Parkinson's Disease, Alzheimer's Disease, neurotoxic injury, head trauma injury, spinal trauma injury or any other form of nerve damage.
Patent GB-0009310-D0 (GB)
Title: Fuel oil compositions
IPC: C10L1/18
Filed: 2000-04-17
Abstract: Oils having improved lubricity and low temperature properties and additives for use therein.
Patent GB-0029301-D0 (GB)
Title: Brickwork support system
IPC: E04F13/08
Filed: 2000-12-01
Abstract: A brickwork support system for supporting brickwork cladding comprises a bracket (1,21) and a support member (2,22). The bracket (1,21) is attached through a fixing aperture (4,24) to a bolt extending from a cast-in channel member on a concrete wall. The bracket has a web portion (5,25) which contacts the concrete wall and two outwardly extending flanges (6,26). The flanges (6,26) are each provided with a substantially L-shaped slot (7,27) which receives a corresponding portion of the support member (2,22). The support member is provided with a load bearing projection (17,31) which engages and supports the brick cladding. The arrangement of the slots (7,27) and support member (2,22) allows relative longitudinal sliding movement of the support member (2,22) and bracket (1,21) but prevents relative lateral horizontal movement, vertical movement and relative rotation of the two components. <IMAGE>
Patent GB-0100620-D0 (GB)
Title: Chemical cokpounds V
IPC: A61P25/16
Filed: 2001-01-10
Abstract: A compound of formula (I), wherein X is S or O; R<SUB>1 </SUB>is selected from H, alkyl, aryl, hydroxy, alkoxy, aryloxy, thioalkyl, thioaryl, halogen, CN, COR<SUB>5</SUB>, CO<SUB>2</SUB>R<SUB>5</SUB>, CONR<SUB>5</SUB>R<SUB>7</SUB>, CONR<SUB>5</SUB>NR<SUB>6</SUB>R<SUB>7</SUB>, NR<SUB>6</SUB>R<SUB>7</SUB>, NR<SUB>5</SUB>CONR<SUB>6</SUB>R<SUB>7</SUB>, NR<SUB>5</SUB>COR<SUB>6</SUB>, NR<SUB>5</SUB>CO<SUB>2</SUB>R<SUB>8</SUB>, and NR<SUB>5</SUB>SO<SUB>2</SUB>R<SUB>8</SUB>; R<SUB>2 </SUB>is selected from aryl attached via an unsaturated carbon atom; R<SUB>3 </SUB>is selected from H, alkyl, hydroxy, alkoxy, halogen, CN and NO<SUB>2</SUB>; R<SUB>3 </SUB>is selected from H, alkyl, aryl, hydroxy, alkoxy, aryloxy, thioalkyl, thioaryl, halogen, CN, NO<SUB>2</SUB>, COR<SUB>5</SUB>, CO<SUB>2</SUB>R<SUB>5</SUB>, CONR<SUB>6</SUB>R<SUB>7</SUB>, CONR<SUB>5</SUB>NR<SUB>6</SUB>R<SUB>7</SUB>, NR<SUB>6</SUB>R<SUB>7</SUB>, NR<SUB>5</SUB>CONR<SUB>6</SUB>R<SUB>7</SUB>, NR<SUB>5</SUB>COR<SUB>6</SUB>, NR<SUB>5</SUB>CO<SUB>2</SUB>R<SUB>8 </SUB>and NR<SUB>5</SUB>SO<SUB>2</SUB>R<SUB>8</SUB>; R<SUB>5</SUB>, R<SUB>6 </SUB>and R<SUB>7 </SUB>are independently selected from H, alkyl and aryl or where R<SUB>6 </SUB>and R<SUB>7 </SUB>are in an (NR<SUB>6</SUB>R<SUB>7</SUB>) group, R<SUB>6 </SUB>and R<SUB>7 </SUB>may be linked to form a heterocyclic group, or where R<SUB>5</SUB>, R<SUB>6 </SUB>and R<SUB>7 </SUB>are in a (CONR<SUB>5</SUB>NR<SUB>6</SUB>R<SUB>7</SUB>) group, R<SUB>5 </SUB>and R<SUB>6 </SUB>may be linked to form a heterocyclic group; and R<SUB>8 </SUB>is selected from alkyl and aryl, or a pharmaceutically acceptable salt thereof or prodrug thereof, and the use thereof in therapy and in the treatment or prevention of a disorder in which the blocking of purine receptors, particularly adenosine receptors and more particularly A<SUB>2A </SUB>receptors, may be beneficial, particularly wherein said disorder is a movement disorder such a Parkinson's disease or said disorder is depression, cognitive or memory impairment, acute or chronic pain, ADHD or narcolepsy, or wherein said medicament is for neuroprotection in a subject.
Patent GB-0106345-D0 (GB)
Title: Compounds compositions and processes
IPC: C09D11/00
Filed: 2001-03-14
Abstract: A process for coloration of a substrate comprising applying thereto by means of an ink jet printer a composition comprising a medium and a compound of Formula (1): wherein: A is optionally substituted aryl; B is optionally substituted arylene; and R<1 >and R<2 >are each independently NR<3>R<4>, hydroxy, alkoxy or hydrocarbyl; R<3 >and R<4 >are each independently H, alkoxy or C1-30 hydrocarbyl or R<3 >and R<4 >together with the nitrogen atom to which they are attached represent an aliphatic or aromatic ring system. Also claimed are compounds, compositions and inkjet cartridges for use in an ink-jet printer and substrate printed with an inkjet printer.
Patent GB-0416651-D0 (GB)
Title: Polypeptide
Filed: 2004-07-26
Abstract: The present invention relates to a novel polypeptide chain forming a particular 3 dimensional fold characterized by a beta-sandwich. By altering the amino acid sequence in specific regions of the polypeptide of the invention novel binding characteristics are developed. Methods for the generation of a polypeptide according to the invention and uses of polypeptides of the invention are also described.
Patent GB-0716108-D0 (GB)
Title: Inventory control system
IPC: G06Q10/08
Filed: 2007-08-17
Abstract: An inventory control system and a method of manufacturing an item storage receptacle for the system is disclosed. The item storage receptacle has a plurality of individually-shaped recess for receiving specific inventory items. The storage receptacle may also have a monitoring feature for attaching a monitoring device configured to generate a signal for the system indicating whether the tool is present.
Patent GB-8314918-D0 (GB)
Title: Radiation sensitive compositions
IPC: G03F7/105
Filed: 1983-05-31
Abstract: Radiation sensitive compositions are image-wise exposed and developed to form an image which is then heated to improve its strength as a lithographic printing image or etch resist. The heating is carried out in the presence of a heat sensitive dye which undergoes a colour change at a temperature of at least 180°C so as to obtain an indication of whether or not the heating has been adequate. The dye may be an integral component of the composition or it may be applied to the image, after development, in combination with a substance capable of forming a shield against contaminating residues produced during the heating step.
Patent GB-8422978-D0 (GB)
Title: Connector block
IPC: H01T4/08
Filed: 1984-09-12
Abstract: The subject matter of the invention is a connector block (1) with solderless, non-screwed and stripping-free terminal elements (2, 3) having a polytropic air gap, for terminating dropwire cables (6) and cable wires (7). The terminal elements (2, 3), which comprise a terminal contact (2b, 3b) and a center contact (2a, 3a), have a semi-circular extension (2a') on the underside (2') of the center contact (2a, 3a), the spacing of said semi-circular extension relative to an earth bar (4) mounted in the housing lower half (12) being variable by tilting the earth bar (4) about 180 DEG ; said earth bar (4) is adapted to be mounted at either of two different levels. Thereby it is possible to select a high-voltage spark-gap function.
Patent GB-8429480-D0 (GB)
Title: Phoneme recognition
IPC: G10L21/02
Filed: 1984-11-22
Abstract: Phoneme recognition uses the silence-phoneme and phoneme-phoneme transition spectral information rather than the phoneme information itself. The transition detector features first and second differences in level for each frequency band.
Patent GB-8517699-D0 (GB)
Title: Control system
IPC: G11C8/12
Filed: 1985-07-12
Abstract: A wafer-scale integrated circuit comprises a few hundred modules 10 which can be connected into a long chain by commands sent to the modules along a transmit path set up by way of module inputs XINN, XINE, XINS, XINW from neighbouring modules and outputs thereto XOUTN, XOUTE, XOUTS, XOUTW, only one of which is enabled by one of four selection signals SELN, SELE, SELS, SELW acting both on transmit path logic 20 and on receive path logic 21 in a return path. A RAM unit 23 can be enabled by WRITE to write a block of data sent to RID via the transmit path and can be enabled to READ to read a block of data to ROD for return along the return path. The provision of SELN, etc READ and WRITE is effected by configuration logic 22 which includes a shift register and is responsive to a command mode signal CMND, on a line which runs to all modules in parallel.
Patent GB-8821812-D0 (GB)
Title: Turbine blade repair
IPC: B23P6/00
Filed: 1988-09-16
Abstract: A method of repairing turbine blades (13, 14, 15) where it is required to repair a blade whilst it is in situ on a rotor involves the movement of a lacing wire (20) out of engagement with the blade to be repaired so that the blade may be repaired. The lacing wire may be completely removed from the array and replaced, or a new lacing wire member inserted by providing elongate holes or slots in the blade to enable the lacing wire member or members to be inserted into the blade array.
Patent GB-8829785-D0 (GB)
Title: Picture frame
IPC: A47G1/06
Filed: 1988-12-21
Abstract: There is disclosed a picture frame comprising a plurality of rebated side frame members at least one of which is provided with a part hingedly connected thereto, and movable between a first position in which it lies outside the rebate and a second position in which it lies within the rebate to engage the rear face of a backing sheet or board, and urge same towards the front of the frame.
Patent GB-8909813-D0 (GB)
Title: Travelling wave optical modulator
IPC: G02F1/03
Filed: 1989-04-28
Abstract: A travelling wave optical modulator comprises a Z-cut lithium niobate substrate (4) on which is formed a proton exchanged optical waveguide (10) and a travelling wave electrode (18,20). The optical waveguide (10) is removed from the electrode (18,20) intermittently to bring an optical signal in the optical waveguide (10) back into phase with an electric field passing along the electrode (18,20). The optical signal is delayed relative to the electric field thereby allowing modulation of the optical signal by a non-periodic electric field. The optical waveguide (10) is defined within the boundaries of the top surface of the substrate.
Patent GB-8911949-D0 (GB)
Title: Novel compounds
IPC: C07D491/048
Filed: 1989-05-24
Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: <CHEM>  wherein either one of R1 and R2 is hydrogen and the other is nitro, cyano, halo, CF3 C2F5, formyl, aldoxime, CF3O, NO2-CH=CH-, NC-CH=CH-; a group RxX-wherein Rx is C1-6 alkyl, aryl or heteroaryl either of which may be optionally substituted by one, two or three of C1-4 alkyl, C1-4 alkoxy, nitro, halo, CF3 and cyano; and x is C=O, O.C=O, C=O.O, CHOH, SO, SO2, O.SO, O.SO2, CONH, O.CONH, C=S, O.C=S, C=S.O, CH.SH, SONH, SO2NH, O.SONH, O.SO2NH, CO-CH=CH, C=NHOH, C=NNH2; or a group RyRzNZ- wherein Ry and Rz are independently hydrogen or C1-6 alkyl and Z is C=O, SO or SO2; or a group (RwO)2P(O)W wherein Rw is hydrogen or C1-6 alkyl and W is O or a bond; or R1 is a C3-8 cycloalkyl group or a C1-6 alkyl group optionally substituted by a group which is hydroxy, C1-6 alkoxy, amino optionally substituted by one or two C1-6 alkyl groups, C1-7 alkanoylamino, C3-8 cycloalkyloxy or C3-8 cycloalkylamino; and R2 is hydrogen; or one of R1 and R2 is nitro, cyano or C1-3 alkylcarbonyl and the other is a different group selected from nitro, cyano, halo, C1-3 alkylcarbonyl, methoxy or amino optionally substituted by one or two C1-6 alkyl or by C2-7 alkanoyl; or R1 and R2 together with the carbon atoms to which they are attached, form 2,1,3-oxadiazole; either one of R3 and R4 is hydrogen or C1-4 alkyl and the other is C1-4 alkyl; or  R3 and R4 together are C2-5 polymethylene;  R5 is hydrogen, hydroxy, C1-6 alkoxy or C1-7 acyloxy; and  R6 is hydrogen; or  R5 and R6 together form a bond; R7 is C1-6 alkyl or phenyl C1-4 alkyl optionally substituted in the phenyl ring by up to three moieties selected from C1-4 alkyl, C1-4 alkoxy or halo; and  R8 is amino, hydrogen or methyl; which are potassium channel activators, a process for their preparation and their pharmaceutical use.
Patent GB-8927377-D0 (GB)
Title: Improvements in and relating to amperometric assays
IPC: G01N27/42
Filed: 1989-12-04
Abstract: A photo-ablation technique is used to create apertures (4) in a layer (2) of electrically insulating material and allow electrically conducting material (3) exposed through the apertures to create a microelectrode. The microelectrode can be used for assay methods and in an assay unit.
Patent GB-9014932-D0 (GB)
Title: Recombinant dna product and method
IPC: C07K16/00
Filed: 1990-07-05
Abstract: The present invention provides humanized antibody molecules (HAMs) having specificity for carcinoembryonic antigen (CEA) and having an antigen binding site wherein at least one of the complementarity determining regions (CDRs) of the variable domains is derived from the mouse monoclonal antibody A5B7 (A5B7 MAB) and the remaining immunoglobulin-derived parts of the HAM are derived from a human immunoglobulin. The HAMs may be chimeric humanized antibodies or CDR-grafted humanized antibodies and are preferably produced by recombinant DNA techniques. The HAMs are useful for in vivo diagnosis and therapy.
Patent GB-9021340-D0 (GB)
Title: Self-centring clutch bearing device of the traction type
IPC: F16D23/14
Filed: 1990-10-01
Abstract: A clutch bearing device of the traction type comprises a rolling bearing (2); a guide sleeve (3) having a tubular part (15) capable of sliding on a guide tube (16), and a radial collar (17) in frictional contact with self-centring means exerting an axial force on the rolling bearing held by a supporting element; and means of axial connection (4, 20) between the rolling bearing and the clutch diaphragm (23). The self-centring means comprise a self-centring bracket (19) having a fastening part (29) capable of interacting with the non-rotating ring (7) of the rolling bearing, and a resilient part (32) capable of exerting an axial force between the radial collar (17) of the guide sleeve (3) and the rolling bearing (2). A seal may be formed or mounted between the bracket (19) and either one of the rings (6, 7) of the rolling bearing (2) (Figs 3-5). <IMAGE>
Patent GB-9216300-D0 (GB)
Title: Viewing apparatus
IPC: G02C7/00
Filed: 1992-07-31
Abstract: Viewing apparatus for viewing an electronic display comprises a lens support (1). At least one magnifying lens (2) is mounted in the lens support (1). The lens (2) includes a filter having magnification and filter characteristics which are predetermined in accordance with the type of display to be viewed. The lenses (2) may be removable from the lens support and a set of lenses provided suitable for different types of support.
Patent GB-9303458-D0 (GB)
Title: Novel compositions
IPC: A61K8/00
Filed: 1993-02-19
Abstract: The problem of providing a storage stable anti-calculus toothpaste comprising a tripolyphosphate salt is remedied by incorporating more than 4% of the salt and having the pH from about 8 to about 10. A tripolyphosphate salt may also be combined with a noncationic anti-bacterial agent such as triclosan to provide a composition having anti-calculus and anti-plaque activity.
Patent GB-9403932-D0 (GB)
Title: Improvements in laminated work surfaces
IPC: A47B77/02
Filed: 1994-03-01
Abstract: The underside edge of a laminated kitchen work surface or work top 1, in which a groove 3 is formed in the underside surface at or adjacent to said edge, is sealed by applying a rib 5 and a film 6 of water-impervious sealant to fill the groove and to extend over an adjacent edge region. The sealant may be a one-part polyurethane-reactive hot melt adhesive and is applied using a coating head having slots (13, 17, Fig. 2). The film 6 may extend into a second groove 4. <IMAGE>
Patent GB-9705584-D0 (GB)
Title: Operation of rotary kilns
IPC: C03B5/14
Filed: 1997-03-18
Abstract: A method of operating a rotary kiln for thermally processing feed material such as cement, lime or the like in which liquid oxygen is injected into the kiln so as to impact on the feed material therein. <IMAGE>
Patent GB-9802570-D0 (GB)
Title: Propulsion system
IPC: B63H3/04
Filed: 1998-02-07
Abstract: A propulsion system for a water craft having at least one shaft extending rearwardly form the transom of the hull of the craft and a drive system for driving the at least one shaft. A surface piercing propeller is mounted on the at least one shaft, proximal to the trailing edge of the hull, so that the propeller operates in a transom cavity created behind the hull, in use of the craft. The ratio (S/C) of the spacing of the blades to the blade cord for each propeller is at least 2.0 along substantially the whole length of the blades. The propulsion system has a high operational efficiency particularly suited for high speed marine craft.
Patent HU-9200299-D0 (HU)
Title: Process for the production of imidazole- triazole- and tetrazole-derivatives and of medical preparations containing them
Inventor: BAKER RAYMOND
IPC: C07D417/14
Filed: 1992-01-31
Abstract: A class of substituted imidazole, triazole and tetrazole derivatives are selective agonists of 5-HT1-like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated. <CHEM> wherein the broken circle represents two non-adjacent double bonds in any position in the five-membered ring; two, three or four of V,W,X,Y and Z represent nitrogen and the remainder represent carbon provided that, when two of V,W,X,Y and Z represent nitrogen and the remainer represent carbon, then the said nitrogen atoms are in non-adjacent positions within the five-membered ring;   A<1>   represents hydrogen, methyl, ethyl, benzyl or amino; A<2>   represents a non-bonded electron pair when four of V,W,X,Y and Z represent notrogen and the other represents carbon; or, when two or three of V,W,X,Y and Z represent nitrogen and the remainder represent carbon, A<2> represents hydrogen, methyl, ethyl, benzyl or amino; E   represents a bond or a straight or branched alkylene chain containing from 1 to 4 carbon atoms; F   represents a group of formula <CHEM>   U   represents nitrogen or C-R<2>; B   represents oxygen, sulphur or N-R<3>; R<1>   represents -CH2.CHR<4>.NR<6>R<7> or a group of formula   <CHEM> in which the broken line represents an optional chemical bond; and R<2>,R<3>,R<4>,R<5>,R<6> and R<7> independently represent hydrogen or C1-6 alkyl.