Patent SG-11201806182R-A (SG)
Title: Methods of producing viruses
Inventor: TOON LINDSEY ANN
IPC: C12N5/071
Filed: 2017-02-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 10 August 2017 (10.08.2017) WIPO I PCT (10) International Publication Number WO 2017/134441 Al 111111111111110111011111111111010111110111011101111110111011111011111111111110111111 (51) International Patent Classification: A61K 39/12 (2006.01) C12N 5/071 (2010.01) (21) International Application Number: PCT/GB2017/050259 (22) International Filing Date: 2 February 2017 (02.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1601861.6 2 February 2016 (02.02.2016) GB 1618549.8 3 November 2016 (03.11.2016) GB (71) Applicant: BENCHMARK ANIMAL HEALTH LIM- ITED [GB/GB]; Benchmark House, 8 Smithy Wood Drive, Sheffield South Yorkshire S35 1QN (GB). (72) Inventors: TOON, Lindsey Ann; 1 Waxwing Close, Wa- termead, Aylesbury Buckinghamshire HP19 OWT (GB). HOFFMANN, Ralf; 4 Courtaulds Mews, High Street, Braintree Essex CM7 1FS (GB). (74) Agent: MITCHELL, Simon; Urquhart-Dykes & Lord LLP, One Euston Square, 40 Melton Street, London Great- er London NW1 2FD (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with (an) indication(s) in relation to deposited biological material furnished under Rule 13bis separately from the description (Rules 13bis.4(d)(i) and 48.2(a)(viii)) W O 20 17 / 13 4441 Al (54) Title: METHODS OF PRODUCING VIRUSES (57) : Methods of producing, propagating and multiplying viruses, methods of identifying the presence of a virus in a sample, specifically methods using Japanese eel cell cultures. Also provided are an isolated Japanese eel cell culture, optionally in- fected with a virus, vaccines comprising viruses grown according to the methods of the invention, and a kit for propagating viruses comprising the Japanese eel cell culture. The virus may be a fish virus such as nodavirus, Infectious Pancreatic Necrosis Virus (IPNV) and Salmon Pancreas Disease Virus (SPDV).