Patent SG-11201806726S-A (SG)
Title: Anti-bacterial patterned surfaces and methods of making the same
Inventor: ZHANG YUGEN
IPC: C23C22/63
Filed: 2017-02-13
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/138890 Al 17 August 2017 (17.08.2017) WIPO I PCT 111111111111110111011111111111010111110111111110111H110111101111111111111110111111 C (51) International Patent Classification: A01N 25/34 (2006.01) C23C 22/63 (2006.01) B82B 1/00 (2006.01) B82Y 5/00 (2011.01) B82B 3/00 (2006.01) B82Y 30/00 (2011.01) C23C 22/60 (2006.01) B82Y 40/00 (2011.01) (21) International Application Number: PCT/SG2017/050063 (22) International Filing Date: 13 February 2017 (13.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 10201601055Y 12 February 2016 (12.02.2016) SG (71) Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH [SG/SG]; 1 Fusionopolis Way, #20-10 Connexis North Tower, Singapore 138632 (SG). (72) Inventors: ZHANG, Yugen; c/o Institute of Bioengineer- ing and Nanotechnology, 31 Biopolis Way, The Nanos #04-01, Singapore 138669 (SG). YI, Guangshun; c/o In- stitute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos #04-01, Singapore 138669 (SG). (74) Agent: SPRUSON & FERGUSON (ASIA) PTE LTD; P.O. Box 1531, Robinson Road Post Office, Singapore 903031 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: of inventorship (Rule 4.17(iv)) [Continued on next page] (54) Title: ANTI-BACTERIAL PATTERNED SURFACES AND METHODS OF MAKING THE SAME (57) : The present invention relates to a sub- strate comprising a plurality of integrally formed surface features, said surface features being micro-sized and/or nano-sized, said surface features comprising at least one pointed terminus. As a result of this unique surface, said substrate exhibits a biocidal activity because the terminal ends of said surface feature pierce through cell mem- = bran of any microbial cell that comes into contact with ;ri the substrate, thereby causing cell deformation and lysis. The present invention also relates to a method producing said substrate. By a simple treatment of copper or zinc foil with a reagent solution comprising an alkali and an oxidizing agent, Cu(OH)2 nanotube arrays, CuO nano- blades and ZnO nano-needles are prepared. These sur- faces are proven to be very effective in killing bacterial (such as E. coli) via a physical interaction. W O 20 17 / 138890 Al tc-IN X.Pag..t) 1 ttatifq 441) 10.:s1 ms, - (C) WO 2017/138890 Al MIDEDIMOM0101011101010M01110EIMEHOMOMOVOIMIE Published: — with international search report (Art. 21(3))