baber/WOPTO huggingface dataset:
Patent CA-2289918-A1 (CA)
Inventor: VANDEN DRIESSCHE THIERRY
IPC: C12N5/10
Filed: 1998-05-18
Abstract: La présente invention concerne un procédé pour la transduction ex vivo de cellules de mammifères, en particulier, pour la transduction de cellules du stroma de la moelle osseuse. Ces cellules peuvent être transduites avec un gène interessant, en particulier le gène du facteur VIII de l'homme supprimé du domaine B. Dans ce dernier cas, les cellules transduites peuvent permettre de traiter l'hémophilie A. Le procédé pour la transduction ex vivo des cellules du stroma de la moelle osseuse avec le gène du facteur VIII de l'homme consiste à prévoir un vecteur rétroviral à base d'intron, comprenant un ADNc du facteur VIII de l'homme supprimé du domaine B (désigné par MFG-FVIII.DELTA.B); à pseudotyper ce vector avec l'enveloppe du virus (GALV) de la leucémie du singe Gibbon; à transduire les cellules du stroma de la moelle osseuse avec ce vecteur pseudotypé en pré-incubant les cellules pendant un laps de temps approprié dans un milieu de culture cellulaire sans phosphate. Ce procédé consiste à ajouter ensuite un surnageant contenant un vecteur, éventuellement complété par des additifs de transduction des cellules avant de centrifuger le mélange ainsi obtenu, puis à répéter éventuellement les deux étapes précédentes.
Patent CA-2291541-A1 (CA)
Inventor: PIDUGU VIJAYA K
IPC: C09D175/06
Filed: 1999-12-03
Abstract: An aqueous, two component system for coating a substrate includes either a filler incorporated in both components prior to combining the components or an elevated amount of a filler, such as 50 % by dry volume, in either component. The filler is preferably calcium carbonate, but may also be selected from titanium dioxide, sand, clay, mica, dolomite, silica, talc, perlite, gypsum, wallastonite, aluminum trihydrate, zinc oxide, barium sulfate, zinc sulfate, and combinations thereof. The first component includes a first polymer containing hydroxyl functional groups or amine functional groups and, optionally, a catalyst, preferably an organotin catalyst. The first polymer is selected from a polyester polyol, an acrylic polyol, a urethane polyol, a polyether polyol, a polyamine, an aldimine, a short oil alkyd, a silicone polyol, a cellulose ester, a vinyl polyol, and combinations thereof and preferably is a polyaspartic ester. The second component includes a second polymer which is polyisocyanate containing isocyanate functional groups. The coating can be applied by applying to the substrate the first component then separately applying the second component shortly thereafter. Alternatively, the components can first be mixed then applied to the substrate as a mixture.
Patent CA-2296292-A1 (CA)
Title: Secreted proteins encoded by human chromosome 13
Inventor: GILBERTSON DEBRA G
IPC: A61K48/00
Filed: 1998-07-24
Abstract: The present invention relates to polynucleotide and polypeptide molecules a for zsig46 polypeptide, a novel secreted protein located on human chromosome 13. The zsig46 polypeptides, and polynucleotides encoding them, are secreted proteins and may be used in the study of receptors for which a ligand has not yet been identified, of secretory pathways and the like. The present invention also includes antibodies to the zsig46 polypeptides.
Patent CA-2297736-A1 (CA)
Inventor: SHEPPARD DEAN
IPC: C12R1/91
Filed: 1998-08-07
Abstract: Procédés et compositions contenant des antagonistes de .alpha.v.beta.6 afin de traiter des fibroses et des lésions pulmonaires aiguës.
Patent CA-2298179-A1 (CA)
Title: Improved self-locking internally threaded fastener and method of manufacture
Inventor: DUFFY RICHARD J
IPC: F16B39/22
Filed: 2000-02-11
Abstract: The present invention is directed to an internally threaded prevailing-torque type self-locking fastener which employs a patch of fused thermoplastic material as the locking element and which satisfies the functional torque requirements of both IFI    (1987) and IFI 101 (1987). In accordance with the present invention the fastener comprises a metal body having a bore extending to its opposing ends, the bore having a threaded surface; a patch of polymeric material applied and fused to a portion of the threaded surface; and the fastener meeting the prevailing-torque characteristics specified in both IFI 100/107 (1987) and IFI 101 (1987). The invention is also directed to a process wherein an internally threaded fastener is processed by first applying and fusing a polymeric resin material to at least a portion of the fastener's threaded surface and thereafter conditioning the frictional properties of the fastener such that its prevailing torque performance characteristics meet both IFI 100/107 (1987) and (1987).
Patent CA-2298533-A1 (CA)
Title: Reduction enantioselective de cetones avec un systeme agent silanique/compose metallique/ligand chiral
Inventor: MIMOUN HUBERT
IPC: B01J31/00
Filed: 1998-09-03
Abstract: The invention concerns a method for the enantioselective reduction of prochiral ketones into chiral alcohol's comprising the following steps: a) reacting a prochiral ketone with a silane agent, present in stoichimetric amount, in the presence of a catalyst derived from a precursor compound of Zn, Co or Cd and of a chiral ligand selected from the group consisting of chiral amines, imines, alcohol's or aminoalcohol's; b) hydrolysis of resulting siloxane using an appropriate agent; c) separating and purifying the resulting optically active alcohol. In one preferred embodiment, polymethylhydrosiloxane (PMHS) is used as silane agent. The preferred metal is Zn. The precursor compound is produced by reacting a salt or complex of the particular metal with a reducing agent; in another embodiment, an appropriate salt of the selected metal is used in the reaction with the chiral ligand, to produce the catalytic agent, after reaction with the ligand. The method is useful for obtaining high enantiomeric excesses (ee) in chiral alcohol's.
Patent CA-2299305-A1 (CA)
Title: Functionalized diene oligomers
Inventor: ITTEL STEVEN DALE
IPC: C08F4/26
Filed: 1998-08-18
Abstract: This invention relates to the controlled molecular weight production of macromonomers and polymers with terminal conjugated double bonds from starting monomers including, but not limited to, substituted butadienes. The terminal diene end thus produced is also a potential reaction site for further polymerization or functionalization. The molecular weight is controlled by use of Co chain transfer catalysts and appropriate process conditions.
Patent CA-2302039-A1 (CA)
Title: Mops and mop components
Inventor: SPECHT PAUL B
IPC: A47L13/146
Filed: 1998-01-15
Abstract: Disclosed is a butterfly mop having an elongate shaft (21) with a channel body (50) disposed at one end of the shaft, the channel body having first and second leg portions (51, 52) defining a channel therebetween, the mop further having a mop element (26) including a foldable, compressible, liquid-absorbent member. The mop element and channel body are hingedly movable along a hinge line (62) relative to one another, whereby the mop element may be drawn into the channel causing the mop element to fold along a transverse axis and to become compressed between the channel body leg portions. A manual actuation mechanism includes a handle (66) and a tension rod (68) connecting the handle to one of the mop element and channel body for effecting relative hinged movement thereof. The mop element preferably includes plural pairs of apertures (135-138) for allowing mounting of the mop element to variously sized mop element supports.
Patent CA-2303834-A1 (CA)
Title: Secreted and transmembrane polypeptides and nucleic acids encoding the same
Inventor: WOOD WILLIAM I
IPC: C07K14/47
Filed: 1998-09-16
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptides molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2306123-A1 (CA)
Inventor: GANESAN RAVI
IPC: G06Q30/04
Filed: 2000-04-14
Abstract: Network stations are used to electronically pay bills. Each station represents a different user, including payers and payees.    Each user has a payment account maintained at one of a plurality of different financial institutes. An instruction to make payment of a bill of a payee is received, via a network, from a user station representing a payer. A directive, directing a transfer of. funds from the payment account associated with the payer and maintained at a first financial institute to a deposit account associated with the payee and maintained at a second financial institute, is generated based on the received payment instruction. Remittance information associated with payment of the bill by the fund transfer is also generated. The directive is transmitted to the first financial institute. The remittance information is stored in a central database so as to be,accessible, via the network, to a user station representing the payee.
Patent CA-2307398-A1 (CA)
Title: Method for removing an aluminide coating from a substrate
Inventor: SANGEETA D
IPC: C23F1/20
Filed: 2000-05-02
Abstract: A method for removing an aluminide coating from a substrate includes the steps of contacting the surface of the substrate with at least one stripping composition to degrade the coating. The stripping composition includes an aliphatic or aromatic sulfonic acid, and at least one additive. The coating is then removed.
Patent CA-2308471-A1 (CA)
Inventor: CAPANNA FRANCO
IPC: B61L23/34
Filed: 1998-11-12
Abstract: The invention concerns a railways means anti-collision and anti-derailment safety system comprising a self-propelled trolley (1) remote controlled from the train locomotive, able to proceed in front of the same train (2), at a suitable distance, or frontally coupled to the same train (2), when the train is stopped, or during the crossing of critic switching platforms, and provided with sensor means (3) to reveal anomalies, obstacles, etc. along the railroad; an integration system between the train (2) and the trolley (1), to pilot the trolley (1) from the train (2) and transfer from the trolley (1) to the train (2) any information revealed; and a trolley (1) self-elimination system, with forced ejection from the railroad.
Patent CA-2309049-A1 (CA)
Inventor: HEIMBROCK RICHARD H
IPC: H04W68/00
Filed: 1998-11-06
Abstract: An integrated personal communcation and data entry device (10) includes a portable housing (12) and an internal controller (26) coupled to the housing.  A paging device (30) and a voice recording device (28) are coupled to the controller. A system for paging members of a medical team is also provided. A  paging signal dispatch system (40) includes a transmitter (42) configured to broadcast a paging signal to page a plurality of pagers (10, 30) simultaneously and a receiver (44) configured to receive page acknowledge return signals from the pagers. Each pager includes a receiver (30, 32) configured to receive the paging signal and a transmitter (30, 32) configured to send a page acknowledge signal. The pager is configured to send the page acknowedge signal based on an input to the user input device (18).
Patent CA-2309495-A1 (CA)
Inventor: HEINZ HENRY JR
IPC: H01M50/533
Filed: 1998-11-12
Abstract: A miniature galvanic cell, preferably a zinc-air cell, employing a two-part housing (2, 34) and a sealing gasket (18) comprises a current collector (30) that extends from one of the housing parts, preferably a flanged cup (34), through an opening (28) in the gasket (18) into the electrode material (38). The gasket material (18), preferably a plastic material, extends over the internal surface of at least one of the housing parts (34) and over a portion of the current collector (30), to expose a low area current collector surface to the electrode material (38), thus preventing or minimising the formation of gases, such as hydrogen, on the current collecting surface. A gasket for use in such a cell and a process for producing such a cell are also disclosed.
Patent CA-2312484-A1 (CA)
Inventor: DEL VECCHIO ALFRED
IPC: A61K48/00
Filed: 1998-12-09
Abstract: L'invention porte sur des polypeptides du virus NS5B (HCV NS5B) de l'hépatite C et l'ADN (ARN) codant pour eux, sur des procédés d'obtention desdits polypeptides par des techniques de recombinaison, et également sur des procédés recourant aux polypeptides HCV NS5B pour le criblage de composés antiviraux.
Patent CA-2313046-A1 (CA)
Inventor: HANSSON ROY
IPC: B32B5/02
Filed: 1998-10-07
Abstract: Absorbent article, such as a diaper, pant diaper, incontinence guard, sanitary napkin, wound dressing and the like, comprising a layer of continuous fibres, so-called tow, which have been bonded together in points, lines or spots in a bonding pattern (10), but otherwise are substantially unbonded to each other, wherein the bonding pattern (10) is different in different portions of said layer (5). The layer can either be utilized as a liquid acquisition layer (5) in the article underneath a topsheet (2), as a topsheet (12), or as a combined topsheet and liquid acquisition layer (22).
Patent CA-2314391-A1 (CA)
Title: Multi-layered water-decomposable fibrous sheet
Inventor: TAKEUCHI NAOHITO
IPC: D04H1/26
Filed: 2000-07-24
Abstract: Provided is a multi-layered water-decomposable fibrous sheet with a plurality of layers each having a different fibrous constitution being integrated, including a top layer on a top surface and a back layer on a back surface. The top layer includes fibrillated rayon of at least 3 % by mass of all fibers constituting the top layer. The fibrillated rayon has a degree of beating of at most 700 cc, and has primary fibers of a predetermined fiber length and microfibers extending from the primary fibers. The microfibers are entangled with and/or hydrogen-bonded to at least either of other microfibers and other fibers. The back layer includes fibers containing no fibrillated rayon, the fibers entangled with and/or hydrogen-bonded to each other, or the back layer includes the fibrillated rayon in an amount smaller than that in the top layer. The microfibers of the fibrillated rayon are entangled with and/or hydrogen-bonded to at least either of other microfibers and other fibers.
Patent CA-2318045-A1 (CA)
Inventor: VACANCE MICHEL
IPC: G02B23/16
Filed: 1999-01-22
Abstract: The invention concerns an integrated and compact assembly for isostatic mounting a space telescope secondary mirror on a carrier structure, comprising three mounting devices (12), preferably identical and evenly distributed about an axis of symmetry of the element to be supported. Each device (12) has the shape of a deformable triangle whereof a first branch (14), constituted by at least an arm (30) variable in length, is connected to the carrier structure, and whereof the opposite apex, constituted by a support part (20), is connected to the element to be supported. Frictionless and tight articulations (26) connect the triangle branches, thereby enabling the supported element position to be corrected along six degrees of freedom.
Patent CA-2318758-A1 (CA)
Inventor: HWU RUEY-JEN
IPC: H01S5/10
Filed: 1998-11-23
Abstract: A system and method for generating a laser beam from a semiconductor laser(10) in order to eliminate or substantially reduce filamentation of the laser beam. The system and method utilizes an external optical member such as a reflector (22) to improve or enhance the overall laser beam quality produced. The reflector (22) has a Gaussian intensity profile promoting cavity such as a parabolic cavity (24), with the cavity (24) having a focal length (f) a preselected distance from the cavity surface. The semiconductor laser (10) is positioned such that the facet of the semiconductor laser (10) is at the focal length distance (f) from the cavity surface. The cavity (24) has a modeselecting reflective surface such that the beam has a substantially Gaussian intensity profile. A beam splitter can be optionally employed between the semiconductor laser (10) and the optical reflector (22) for certain applications if desired. Alternatively, an external digital optics member can be employed with a semiconductor laser (10) to produce a beam with a substantially Gaussian intensity profile.
Patent CA-2318839-A1 (CA)
Inventor: KEY EDWARD JOHN
IPC: B01J2/14
Filed: 1999-01-22
Abstract: A granulator comprising a perforate screen located within a housing, a roller having a curved convex outer surface and located within the housing wherein the roller is pivotable relative to the screen so that in operation plastic material is able to be forced through the perforate screen by the roller surface so the roller pivots. The granulator is useful for wet and dry granulation.
Patent CA-2319683-A1 (CA)
Title: Method for controlling laminate gloss
Inventor: PALMER DOROTHY TEPERA
IPC: B44C1/165
Filed: 2000-09-15
Abstract: A method for forming a glossy decorative laminate is disclosed. The method is achieved by stacking a decorative laminate sheet assembly having a top layer, casting a polypropylene release sheet wherein the polypropylene release sheet is processed with chill rollers treated in a manner which improves the gloss characteristics of the resulting decorative laminate, positioning the polypropylene release sheet on the top layer of the decorative laminate sheet assembly, applying heat and pressure to the decorative laminate sheet assembly and the polypropylene release sheet sufficient to bond the decorative laminate and releasably bond the polypropylene release sheet to the top layer of the decorative laminate sheet assembly, and removing the polypropylene release sheet from the top layer of the decorative laminate sheet assembly to reveal a decorative laminate exhibiting desirable gloss characteristics.
Patent CA-2319859-A1 (CA)
Inventor: WATKINS DAVID SCOTT
IPC: H04N5/232
Filed: 2000-09-15
Abstract: A housing (14) separate from a video camera (12) for remote operation and monitoring, having a control pad (16) with a plurality of switches (generally 18) each movable from a first position to a second position to actuate a selected one of a plurality of operative functions of the video camera (12) and a video display device (34) mounted in the housing (14) which communicates with the video camera for displaying images (35) received by the video camera in response to activation of selected operative functions of the video camera. The video display device (34) further displays text and graphics images (37) representative of the operational status of the video camera (12). A bracket (44) for selectively mounting the housing in a motor vehicle is disclosed, whereby police officers are enabled to operated the video camera while also operating a motor vehicle, particularly in emergency situations. A method of remote operation and monitoring of a video camera is disclosed.
Patent CA-2321046-A1 (CA)
Title: Instrumented cable
Inventor: MARTIN LEWIS ALLEN
IPC: G01L5/10
Filed: 1999-02-25
Abstract: The present invention provides an apparatus for providing support to, and/or measuring the stress present in a potentially unstable structure, such as the roof of a coal or other underground mine, or a rock mass. The apparatus is an instrumented cable comprising: (a) a center wire (12) having a length which is greater than its width; (b) a plurality of stress measuring devices (14) attached along the length of the center wire; (c) a forming material (16) which is formed around the center wire and the stress measuring devices; (d) a plurality of noncenter wires (18) having a length which is greater than their width, and being wrapped around the length of the center wire, the stress measuring devices and the forming material; and (e) a device for collecting data (20) produced by the stress measuring devices, which is connected with the stress measuring devices. Advantageously, the apparatus measures the stress placed thereon when inserted into the potentially unstable structure at more than one location along the length thereof, may be spun into a rock mass without damaging the stress measuring devices (or other components of the apparatus) and may be grouted into the potentially unstable structure with a variety of different grouts.
Patent CA-2322434-A1 (CA)
Title: Medicament delivery and packaging
Inventor: CHAWLA BRINDRA PAUL SINGH
IPC: A61M15/00
Filed: 1997-12-17
Abstract: A system for the administration of a powdered medicament by inhaltation comprises a container (21) containing a unit dose of medicament in powder form, and a device (10) having a chamber (16) adapted to receive the container (21). The device (10) has air inlets (19, 20) by which air may be drawn into the chamber (16) and a mouthpiece (14) by which air and entrained medicament may be drawn out of the chamber (16). The chamber (16) is substantially circular or annular in form and, in use, the container (21) follows an orbital path within the chamber (16), medicament being dispensed from the container (21) through at least one opening in the container (21). Also described are packagings for powdered medicaments which are particularly suitable for use in the system.
Patent CA-2325208-A1 (CA)
Title: Coaxial cable and process and apparatus for forming
Inventor: FAUERBACH HENRY J JR
IPC: H01R13/646
Filed: 2000-11-02
Abstract: A method of forming an end of a coaxial cable to prevent the dielectric from receding within the outer conductor is disclosed, together with a cable formed by the method and an apparatus for carrying the method out. The cable comprises a central wire conductor, a dielectric formed of several layers of PTFE tape, and an outer conductor of metal braid. The outer conductor is cut away to expose a substantial length of the dielectric. A shroud is slid over the outer conductor. The shroud carries a spacer lip that abuts the end of the outer conductor, while leaving a gap between the lip and the exposed dielectric. The end of the cable is then inserted into a blind bore in a heated tool. The blind bore fits snugly round the exposed dielectric, but is appreciably shorter.  The tool is forced onto the cable, compressing the dielectric, until the tool meets the spacer lip. The heat of the tool fuses the layers of the PTFE together, and allows the PTFE to flow, forming a bead in the gap inside the spacer lip. The bead engages the end of the outer conductor, preventing the dielectric from receding within the conductor.