baber/WOPTO huggingface dataset:
Patent CZ-295776-B6 (CZ)
Title: Optically pure (+)-norcisapride intended for the treatment of gastro-esophageal reflux
Inventor: MCCULLOUGH JOHN R
IPC: A61K31/495
Filed: 1999-07-23
Abstract: In the present invention, there is disclosed the use of therapeutically effective amount of optically pure (+)-norcisapride or a pharmaceutically acceptable salt thereof for the preparation of a pharmaceutical composition  intended for the treatment or prevention of gastro-esophageal reflux and other diseases.
Patent CZ-302280-B6 (CZ)
Title: Compounds and compositions for delivering active agents
Inventor: GSCHNEIDNER DAVID
IPC: C07C275/42
Filed: 1999-08-06
Abstract: In the present invention, there are disclosed compounds of the general formula I in which n, m and x have specific meanings, which serve for the delivery of active agents, such as biologically active agents or chemically active agents to a place in need of the agent. There are also disclosed compositions containing a biologically active agent and some of selected compounds, a dosage unit form, the use of such composition for the preparation of a pharmaceutical composition, as well as corresponding usages thereof.
Patent CZ-296546-B6 (CZ)
Title: Coating color composition, cellulosic article coated with the coating color composition, and water-soluble polymer comprised in this coating color composition
Inventor: WESTON PHILIP MARK
IPC: C09D11/02
Filed: 2000-07-17
Abstract: In the present invention, there is disclosed a coating color composition comprising an aqueous dispersion of, a) a pigment, b) a binder, c) a fluorescent whitener and d) a water-soluble polymer formed from a water-soluble ethylenically unsaturated monomer or monomer blend, wherein the composition is characterized in that the water-soluble polymer consists essentially of, i) 90 to 100 mole percent of hydrophilic essentially nonionic repeating units and, ii) 0 to 10 mole percent of anionic repeating units and has an average molecular weight of between 50,000 and 500,000.
Patent CZ-299761-B6 (CZ)
Title: Method of comprehensive processing recyclable raw material
Inventor: HOEKL ZDENEK
IPC: B09B3/45
Filed: 2007-07-30
Abstract: The present invention relates to a method of comprehensive processing recyclable raw material containing organic and optionally also inorganic fraction wherein the inventive method is characterized by the following steps: (1) melting off in a thermolysis zone enclosed to the surrounding atmosphere heat-liquefiable components from the recyclable raw material at optional simultaneous evaporation of the raw material lower boiling fraction; (2) evaporation a higher boiling fraction from the rest of the raw material remained after melting-off procedure and optional evaporation of the lower boiling components wherein said higher boiling fraction is supplied in the form of a secondary gaseous phase into a fractional distillation zone where said secondary gaseous phase is separated by fractionation to gaseous and/or liquid components; (3) subjecting the remainder after evaporation of the higher boiling fraction from the raw material and optionally a remainder from the fractional distillation zone bottom in the thermolysis zone to a high-temperature decomposition to obtain a tertiary gaseous phase being supplied to the fractional distillation zone and a residue that is supplied, after optional separation of the inorganic fraction and optionally together with the remainder obtained from the bottom of the fractional distillation zone, into a plasma zone where said remainder is converted in an oxidizing atmosphere to a gaseous component rich in carbon monoxide.
Patent CZ-289935-B6 (CZ)
Title: Device for adjusting bed in a couchette car
Inventor: BORUTA IVAN ING
IPC: B61D31/00
Filed: 2000-10-16
Abstract: The proposed device for adjusting a bed in a couchette car is characterized in that the bed (1) is provided with abed pin (5) and an arm pin (6) serving for mounting and arm (2), whereby said arm (2) other end is mounted by means of a hinge pin (4) in an upper groove (7) of a cover plate (3), while said bed pin (5) is mounted in said cover plate (3) bottom groove (8). On the cover plate (3) in the upper and bottom portions thereof, there are rotatably mounted identical securing elements (10) coupled by means of a pull rod (9) with each other, whereby said pull rod (9), being at the same time mounted on a spring (11) and a lever (12) is provided in its bottom portion with a dead stop (17). On said cover plate (3) bottom portion, there is further placed a safety (13) with an adjusting screw (14). A finger (16) is attached to said bed pin (5). Said pull rod (9) bottom end is connected to a controller (15).
Patent CZ-303385-B6 (CZ)
Title: Antithrombotic compound
Inventor: VAN BOECKEL CONSTANT ADRIAAN ANTON
IPC: A61K38/00
Filed: 2000-12-01
Abstract: The present invention relates to pentasaccharide derivatives of the general formula I, wherein R represents independently SOi3 e- or CHi3; the spacer group denotes *- (CHi2CHi2O)i3- (CHi2)i2-NH- C(O)-(CHi2)i3-NH-C(O)-CHi2-, wherein the end indicated with * being attached to the pentasaccharide residue. The invention also relates to a pharmaceutical composition in which the pentasaccharide derivatives are comprised, as well as their use in the treatment or prevention of thrombosis or other thrombin-related diseases.
Patent SK-287404-B6 (SK)
Title: Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4R- (3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-one hydrochloride, method of preparation and pharmaceutical composition comprising the same
Inventor: BAFUS GARY L
IPC: A61K31/00
Filed: 2001-01-08
Abstract: It is described a pseudopolymorph of (-)-cis-2-(2- chlorophenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1- methyl)piperidinyl]-4H-1-benzopyran-4-one hydrochloride, a method of making same, a pharmaceutical composition and methods of using the pseudopolymorph. The method of preparation comprising: a) combining a sufficient quantity of Form I with a sufficient amount of an appropriate azeotropic solvent, thus forming an azeotropic mixture, b) submitting the azeotropic mixture to azeotropic distillation sufficient to form I and c) optionally recovering Form I therefrom.
Patent SK-288807-B6 (SK)
Title: Device for pipe cleaning
Inventor: VIRGALA IVAN
IPC: B08B9/04
Filed: 2016-11-15
Abstract: Device is designed for cleaning the pipeline and possibly also inspecting the condition of the inner wall of the pipeline. The device consists of cleaning brushes (12) fixed by means of screws with nuts (11) to the lids (9), which are fixed to the cylindrical frame (8). Inside the cylindrical frame (8) an electromagnet (1) is mounted on the lid (9) and another electromagnet (1) is connected to a guide rod (4) inserted in the opening of the impact mass (2) attached by means of a housing (3) to the cylindrical frame. (8). There is a spring (5) with an adjusting nut (6) on the guide rod. A spacer (7) is placed between the electromagnets (1). The lid (9) and the housing (3) are fixed to the cylindrical frame (8) by means of fixing screws (10).
Patent EP-1777236-B8 (EP)
Inventor: COSTANTINO P
IPC: A61K39/39
Filed: 2003-03-26
Granted: 2017-02-22
Abstract: A modified polysaccharide, in particular a modified  Neisseria meningitidis  serogroup A polysaccharide, which retains immunogenicity but has improved stability. Typically, the modified poly
Patent EP-1218297-B8 (EP)
Inventor: KIM HEE JUNG
IPC: B01D61/44
Filed: 1999-09-03
Granted: 2006-05-03
Abstract: The present invention provides an apparatus for preparing sterilizing water, which comprises an electrolyzer wherein an anode chamber ( 10 ) and a cathode chamber ( 20 ) partitioned by an ion exchange membrane ( 40 ) form a unit cell (A), being alternately arranged and successively equipped with close relation; water inlets ( 61, 62 ) and water outlets ( 71, 72 ) are provided on the end plate ( 60, 70 ) at both ends of the electrolyzer; said anode chamber ( 10 ) and cathode chamber ( 20 ) having circulative openings at the vicinity of each edge at both sides centered from anode plate ( 11 ) and cathode plate ( 21 ), of which two circulative openings of diagonal direction among them have plural passages of fan-shape, in order for water introduced through the openings to pass through the passages to rapidly go through each electrode; and a gap-control gasket ( 30 ) and a gasket for preventing leakage of electrolyte ( 31 ) having plural horizontal members are provided at the center to form an anode reaction chamber ( 13 ) and a cathode reaction chamber ( 23 ).
Patent BR-PI0012196-B8 (BR)
Title: artigo industrializado
Inventor: MARK X SLIWKOWSKI
IPC: A61K47/48
Filed: 2000-06-23
Abstract: "método de tratamento de um tumor em mamíferos através do uso de conjugados de maitansinóide e anticorpo receptor anti-erbb e artigo industrializado". o presente pedido refere-se a métodos de tratamento que utilizam conjugados de maitansinóide e anticorpo receptor anti-erbb e artigos industrializados apropriados para utilização nesses métodos. particularmente, a presente invenção refere-se a terapias de câncer dirigidas por receptor de erbb, utilizando conjugados de maitansinóide e anticorpo receptor anti-erbb.
Patent BR-PI0016249-B8 (BR)
Inventor: ARMSTRONG LYLE
IPC: C12Q1/42
Filed: 2000-12-11
Abstract: An alizarin-based chromogenic substrate, a composition containing the substrate, and its use to detect the presence of an enzymatic activity are disclosed. The substrate is particularly applicable in the field of biological diagnosis.
Patent BR-PI0114933-B8 (BR)
Inventor: SUNE WIKNER
IPC: A61P9/10
Filed: 2001-09-27
Abstract: An oral preparation for reduction of mammalian, e.g. human, cat or dog, plaque and/or calculus, such as bacterial plaque, arteriosclerotic plaque, atherosclerotic plaque, pleural plaque, dental calculus, renal calculus, biliary calculus, and prostatic calculus, contains a Ascophyllum sp., especially A. nodosum, seaweed or an extract thereof. The oral preperation is suitable for use in prophylactic and/or therapeutic method of treating plaque and/or calculus in a mammalian individual.
Patent BR-PI0416373-B8 (BR)
Inventor: HELMUT SCHMIDT
IPC: A61M1/14
Filed: 2004-10-22
Abstract: A connector for connecting a dialysate port of a dialyzer with a dialysate-carrying line and a dialyzer. The connector has a recess with a shift element on the end which accommodates the dialyzer port. The shift element is accommodated in the recess and is displaceable between a first position and a second position perpendicular to the direction of the lumen on the first end. The shift element does not pass through the lumen in the first position. In the second position, the lumen is constricted so that the connector with the shift element can be placed on the dialysate port and the connector locked on the dialysate port through engagement of the shift element behind an undercut on the port.
Patent BR-PI0601580-B8 (BR)
Inventor: EUGENE L TIMPERMAN
IPC: A61B17/11
Filed: 2006-05-05
Abstract: A surgical tool (10) for deploying an anastomotic ring (14) comprises a handle (17) and a ring deployment mechanism (24) at the distal end of a shaft (18). The ring deployment mechanism has a distal portion and a proximal portion, and is moveable from an unactuated position to an actuated position to deploy an anastomotic ring. To prevent tissue from becoming trapped in the deployment mechanism during insertion or extraction of the tool, distal and proximal sheaths (32,34) are configured to cover distal and proximal portions of the ring deployment mechanism, respectively. An actuation mechanism in the handle permits advancement of the distal sheath and actuation of the distal portion of the ring deployment mechanism with a single movement of a first actuator slider (26). The actuation mechanism also permits retraction of the proximal sheath and actuation of the proximal portion of the ring deployment mechanism with a single movement of a second actuator slider (28).
Patent BR-PI0607811-B8 (BR)
Title: derivados de óxido de pirimidina de 2-(4-cianofenilamino) inibidores de hiv, composição farmacêutica compreendendo os mesmos, processo para preparar a referida composição e uso
Inventor: HERMAN AUGUSTINUS DE KOCK
IPC: A61P31/18
Filed: 2006-02-20
Abstract: derivados de óxido de pirimidina de 2-(4-cianofenilamino) inibidores de hiv, composição farmacêutica compreendendo os mesmos, processo para preparar a referida composição e uso. os inibidores de replicação de fórmula (i), um sal de adição farmaceuticamente aceitável; ou uma forma estereoquimicamente do mesmo; em que r1 é halo; r2 e r3 cada qual independentemente é c1-6aiquila. composições farmacêuticas contendo estes compostos como ingrediente ativo e processos para preparar estes compostos e composições.
Patent BR-PI0616960-B8 (BR)
Title: uso de lactobacilo para o tratamento de infecções virais
Inventor: AGNES WOLD
IPC: C12R1/225
Filed: 2006-10-06
Abstract: uso de lactobacilo para o tratamento de infecções virais. a presente invenção refere-se ao uso de pelo menos uma cepa de bactéria probiótica selecionada dos lactobacilos, para a fabricação de uma composição farmacêutica para o tratamento e/ou prevenção de uma infecção viral.
Patent BR-PI0712162-B8 (BR)
Title: composição de 1,2-benzisotiazolin-3-ona ou sais da mesma, seu uso, complexo de 1,2-benzisotiazolin-3-ona imobilizada/óxido de zinco e seu método de preparação
Inventor: WOLFGANG LINDNER
IPC: C07F3/06
Filed: 2007-04-20
Abstract: MÉTODO DE FABRICAÇÃO DE UM COMPLEXO DE 1,2-BENZISOTIAZOLIN-3-ONA IMOBILIZADA/ÓXIDO DE ZINCO, O REFERIDO COMPLEXO, MÉTODOS PARA A PROTEÇÃO DE SUBSTRATOS CONTRA INFESTAÇÕES MICROBIANAS E PARA A FABRICAÇÃO DE UM CONCENTRADO DE DISPERSÃO DE UM COMPLEXO DE 1,2-BENZISOTIAZOLIN-3-ONA IMOBILIZADA/ÓXIDO DE ZINCO, COMPOSIÇÃO DE 1,2-BENZISOTIAZOLIN-3-ONA OU SAIS DA MESMA E USO DA REFERIDA COMPOSIÇÃO. A presente invenção oferece novos complexos antimicrobianos de 1,2-benzisotiazolin-3-ona imobilizada/óxido de zinco (BIT/ZnO) úteis como agentes antimícrobianos devido a sua resistência à lixiviação do substrato ao qual estão ligadas. A presente invenção ainda refere-se aos métodos para preparação dos complexos BIT/ZnO, aos complexos Bit/Zno preparados pelos novos métodos, aos métodos para utilização dos complexos BIT/ZnO na inibição do crescimento microbiano ou na redução do nível de bactérias sobre a superfície de um substrato e aos substratos protegidos do ataque microbiano através do tratamento com os complexos BIT/ZnO complexos. A presente invenção ainda refere-se às composições contendo 1,2- benzisotiazolin-3-ona imobilizada com óxido de zinco.
Patent BR-PI0906495-B8 (BR)
Title: compostos derivados de indolil-piridona e composição farmacêutica
Inventor: ANDREA FIUMANA
IPC: C07D401/14
Filed: 2009-01-20
Abstract: derivados de indolil-piridona tendo atividade inibidora de quinase de ponto de checagem 1. a presente invenção refere-se aos compostos de fórmula (i), que têm atividade inibidora de quinase de ponto de checagem 1 (chk1), em que: r1, r2, r5 e r6 são independentemente selecionados a partir de hidrogênio, hidróxi, metila, trifluorometila, hidroximetila, metóxi, trifluorometóxi, metilamino e dimetilamino; r3 e r4 são independentemente selecionados a partir de hidrogênio, hidróxi, c1-c3 alquila, flúor-(c1-c3)-alquila, hidróxi-(c1-c3)-alquila, c1-c2 alcóxi, flúor-(c1-c3)-alcóxi, hidróxi-(c1-c3)-alcóxi, -n(r11)-r12, -alk-n(r11)-r12, -o-alk-n(r11)-r12, -c(=o)oh, carbóxi-(c1-c3)-alquila, ou - c(=o)-nh-r13; alk é um radical c1-c6 alquileno divalente de cadeia linear ou ramificada; r7 e r8 são independentemente selecionados a partir de hidrogênio, hidróxi, ou c1-c3 alcóxi; x é um radical c1-c3 alquileno divalente de cadeia linear, opcionalmente substituído em um ou mais carbonos por r9 e/ou r10; w é selecionado a partir de -c(=o)-n(-t16)- ou -n(-r17)-c(=o)-; y é hidrogênio, c1-c3 alquila, c1-c3 alcóxi, ou halo; e q é selecionado a partir da fenila opcionalmente substituída, ciclo-hexila opcionalmente substituída, ou um anel heteroarila monocíclico de 6 membros opcionalmente substituído.
Patent EA-024702-B8 (EA)
Title: Novel immunomodulator and anti inflammatory compounds
Inventor: MUTHUPPALANIAPPAN MEYYAPPAN
IPC: C07D319/18
Filed: 2011-05-06
Abstract: The present invention provides dihydroorotate dehydrogenase inhibitors of formula (I), pharmaceutical compositions containing them and methods of treatment of diseases or disorders wherein the inhibition of dihydroorotate dehydrogenase is known to show beneficial effect.
Patent AU-2011203525-B8 (AU)
Title: An apparatus for analyzing/processing a sample of biomolecular analyte, device and method
Inventor: TAN EUGENE
IPC: G01N27/26
Filed: 2011-07-12
Granted: 2014-03-06
Abstract: C:WRPonblDCC\PLW3747513_I.DOC-7/ 11/2011 -40 A ruggedized apparatus for analyzing a sample of biomolecular analyte, the ruggedized apparatus comprising: a test module comprising a transparent material that allows at least a 5 part of an energy source to interact with the sample disposed within the test module and at least one channel in fluid communication with the sample; a holder for supporting the test module; an electrophoresis device connected to the holder and for providing energy to the test module; a light source for emitting a light beam that excites fluorescence in the sample of biomolecular analyte; a light detector; a plurality of optical devices mounted within the 10 apparatus to transmit the light beam emitted by the light source to the test module and from the test module to the light detector; and a lanefinding component for automatically determining a location of the at least one channel disposed within the test module. ,42-, 8 0 -90 77/
Patent BR-112014031358-B8 (BR)
Title: Método para preparar um composto de metal de transição compósito de um precursor de metal de transição
Inventor: BYUNG CHUN PARK
IPC: C01G23/00
Filed: 2013-07-03
Abstract: PRECURSOR PARA PREPARAR UM ÓXIDO DE METAL DE TRANSIÇÃO DE COMPÓSITO DE LÍTIO, MÉTODO PARA PREPARAR O PRECURSOR, E ÓXIDO DE METAL DE TRANSIÇÃO DE COMPÓSITO DE LÍTIO. A presente invenção divulga um precursor de metal de transição para preparar um óxido de metal de transição de compósito de lítio, um método para preparar o precursor, e um óxido de metal de transição de compósito de. O precursor de metal de transição inclui um composto de metal de transição compósito tendo uma composição representada pela fórmula (1) e um teor de Mn de 60 a 85% em mol: NiaMbMn1-(a+b)(OH1-x)2(1) onde M é pelo menos um selecionado a partir de um grupo consistindo em Ti, Co, Al, Cu, Fe, Mg, B, Cr, Zr, Zn e metais de transição de período II, 0,15 =< a =< 0,3; 0 =< b =< 0,1 e 0 < x < 0,5. O Óxido de metal de transição de compósito de lítio tem uma composição representada pela fórmula (2) e um teor de Mn de 60 a 85% em mol: Li1+z[NiaMbMn1-(a+b)]2O4-yAy(2) onde M é pelo menos um selecionado a partir de um grupo consistindo em Ti, Co, Al, Cu, Fe, Mg, B, Cr e metais de transição de período II, A é um monoânion ou diânion; 0,15 =< a =< 0,3; 0,005 =< b =< 0,1; -0,1 =< z =< 0,1 e 0 =< y =< 0,1.
Patent BR-112017007482-B8 (BR)
Title: Processo para criar cronômetro de eventos em uma impressora de código de barras de frescor de alimento ou impressora inteligente que vai soar em uma base periódica ou em uma passagem de tempo específica
Inventor: MARK S MORROW
IPC: B65C9/46
Filed: 2014-10-13
Abstract: A presente invenção refere-se ao método de adição de uma pluralidade de cronômetros de evento adaptáveis, para uma impressora de frescor de alimento, ou impressora inteligente (1), que é descrito. Os cronômetros de evento customizáveis são adicionados pelo operador com a finalidade de soar um alarme para indicar um lapso de tempo e/ou imprimir etiquetas em um intervalo pré-determinado. Quando o cronômetro de evento expira e o usuário conhece o som audível, o usuário tem a opção de reiniciar o cronômetro para o próximo evento, ou deletar o cronômetro. Além disso, os cronômetros de evento permitem o usuário ou exibir uma mensagem ou imprimir um lote de etiquetas, quando o cronômetro expira.
Patent EP-1274778-B9 (EP)
Inventor: SOMMER HEINRICH
IPC: C08J9/00
Filed: 2001-01-04
Granted: 2007-01-17
Abstract: Composition that can be foamed from pressurized containers comprises a dispersion of 30-80 wt.% film-forming polymer, 3-25 wt.% propellant gas and 0.3-6 wt.% ionic foam stabilizer(s).
Patent EP-2079732-B9 (EP)
Inventor: HOHLWEG ROLF
IPC: C07D405/04
Filed: 2007-05-22
Granted: 2012-03-21
Abstract: A process for synthesizing 3-(1,3-benzodioxol-5-yl)-6-(4-cyclopropylpiperazin-1-yl)pyridazine, where the process comprises reacting 3-chloro-6-(4-cyclopropyl-piperazin-1-yl)pyridazine with 3,4-methylene-dioxybenzene boronic acid.
Patent EP-0785833-B9 (EP)
Inventor: HAYWARD JOHN
IPC: B21D5/08
Filed: 1995-10-10
Granted: 2002-11-13
Abstract: A method of producing articles in continuous succession by forming from strip material (1) includes partially dividing the strip prior to completion of the forming, to leave adjacent strip portions (1A, 1B) joined by a small connecting portion (15) and parting-off a pair of successive formed articles by severing the portion (15). Apparatus for performing the method includes forming means (5) for forming the strip to the desired profile, means (C) for partially dividing the strip to leave the connecting portion (15), and means (9, 10) for parting-off of a pair of successive formed articles by severing the connecting portion.
Patent DE-3438462-C1 (DE)
Title: Scaler
Inventor: ROEMHILD LUDWIG DR
IPC: A61C17/00
Filed: 1984-10-19
Granted: 1986-01-02
Abstract: The mechanical scaler for cleaning of a tooth from tartar, concrements and root cement has a motor (2) accommodated in a handle (1), a reducing gear (3), an eccentric transmission (4; 8) and a striking pin (5) having a restoring spring (6). A scraping insert (10) is fitted so as to be exchangeable on the striking pin (5) via a quick-action coupling. The eccentric transmission (4; 8) causes the scraping insert to execute a to-and-fro movement in the longitudinal axis of the handle (1) via the striking pin (5), the movement away from the handle (1) taking place relatively slowly and the movement back again taking place relatively quickly. <IMAGE>
Patent DE-3534978-C1 (DE)
Title: Electrical cartridge heating element having a built-in thermocouple
Inventor: HILLINGER ERICH
IPC: H05B3/46
Filed: 1985-10-01
Granted: 1987-05-07
Abstract: In the case of electrical cartridge heating elements having a built-in thermocouple which is used as a heat sensor, it is of major importance that a high level of thermal decoupling be achieved between the thermocouple as such and the heating filament of the heating element, since the measurement results would otherwise be corrupted. This also applies in particular to cartridge heating elements in which the two limbs of the thermocouple are passed forwards within the insulating support of the heating filament to a conical body, which forms one end of the heating element, to form the connection point of the thermocouple located there. The desired thermal decoupling is achieved according to the invention in that the conical body (5) consists of a thermally and electrically insulating material, and the connecting point (12) of the thermocouple is arranged in the tip (at the vertex) of the conical body (5). <IMAGE>