baber/WOPTO huggingface dataset:
Patent AU-699041-B2 (AU)
Title: 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
Inventor: CUPPS THOMAS LEE
IPC: C07D401/12
Filed: 1994-12-15
Granted: 1998-11-19
Abstract: The subject invention relates to compounds having the structure:   <IMAGE>   wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; (b) R' is selected from unsubstituted C114 C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; and halo; and (c) R'' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; methyl monosubstituted with hydroxy, thiol or amino; unsubstituted C1-C3 alkylthio or alkoxy; amino; unsubstituted amide; unsubstituted or C1-C3 substituted amido; halo; unsubstituted sulfoxide; unsubstituted sulfonyl; and cyano; pharmaceutical compositions containing such compounds, and the use of such compounds for preventing or treating respiratory, ocular, and/or gastrointestinal disorders.
Patent AU-606677-B2 (AU)
Title: 17 beta -(cyclopropylimino) androst-5-EN-3 beta- Ol and related compounds useful as C17-20 lyase inhibitors
Inventor: ANGELASTRO MICHAEL R
IPC: A61K31/565
Filed: 1988-04-18
Granted: 1991-02-14
Abstract: This invention is directed to 17 beta -(cyclopropylamino)androst-5-en-3 beta -ol and related compounds and also to a method for using such compounds in the treatment of androgen-dependent disorders. The compounds are prepared by the hydride reduction of an appropriate steroidal imine or enamine.
Patent AU-780463-B2 (AU)
Title: Environmental stress tolerance genes
Inventor: PINEDA OMAIRA
IPC: C07K14/415
Filed: 2000-11-14
Granted: 2005-03-24
Abstract: Recombinant polynucleotides and methods for modifying the phenotype of a plant are provided, and plants having such modified phenotypes. In particular, the phenotype that is being modified is tolerance to heat.
Patent AU-779945-B2 (AU)
Title: Apparatus and method for steering a guidewire and connecting to an extension guidewire
Inventor: HAMILTON PETER A
IPC: A61B19/00
Filed: 2000-11-27
Granted: 2005-02-17
Abstract: An apparatus for steering a guidewire and for connecting the guidewire to an extension guidewire. The apparatus includes a steering device for gripping an exterior of the guidewire, the steering device defining a passageway therein through which the guidewire may pass; and a connecting device for connecting the guidewire to the extension guidewire. The connecting device is configured for mating with the steering device to form an integral unit. The invention further includes a method of inserting a guidewire in a body and connecting the guidewire to an extension guidewire. The method includes the steps of: providing an integral guidewire holder and tool for connecting a guidewire to an extension guidewire; gripping the guidewire with the integral guidewire holder; inserting the guidewire into a body lumen; displacing the integral guidewire holder and tool relative to the guidewire so that the proximal end of the guidewire is located in a slot of the integral guidewire holder and tool; inserting an extension guidewire into the slot of the integral guidewire holder and tool; and connecting the guidewire to the extension guidewire. The method further includes the step of aligning the guidewire and extension guidewire in the slot prior to the connecting step.
Patent AU-779590-B2 (AU)
Title: Antipruritic agents for external use
Inventor: INAMOTO YUKIKO
IPC: A61K31/616
Filed: 2000-12-15
Granted: 2005-02-03
Abstract: External agents for treating pruritus comprises aspirin. ACTIVITY : Antipruritic. In tests a 2 weight% aspirin solution applied to insect bites reduced itching by 85.7 % compared to 60.0 % for a 0.1 weight% dexamethasone composition. MECHANISM OF ACTION : None given.
Patent AU-562520-B2 (AU)
Title: Fibre optic word generator
Inventor: SHAW HERBERT JOHN
IPC: H04B10/04
Filed: 1983-09-08
Granted: 1987-06-11
Abstract: A digital word generator (10) uses a tapped fiber optic delay line (14) to generate a sequence of pulses. The pulses are weighted and combined to produce a digital word.
Patent AU-636816-B2 (AU)
Title: Pyrazolopyrimidinone antianginal agents
IPC: A61K31/535
Filed: 1992-07-08
Granted: 1993-05-06
Abstract: Compounds of formula: <CHEM>  and pharmaceutically acceptable salts thereof,  wherein R<1> is H; C1-C3 alkyl optionally substituted with one or more fluoro substituents; or C3-C5 cycloalkyl; R<2> is H, or C1-C6 alkyl optionally susbtituted with one or more fluoro subtituents or with C3-C6 cycloalkyl; R<3> is C1-C6 alkyl optionally substituted with one or more fluoro substituents or with C3-C6 cycloalkyl; C3-C5 cycloalkyl; C3-C6 alkenyl; or C3-C6 alkynyl; R<4> is C1-C4 alkyl optionally substituted with OH, NR<5>R<6>, CN, CONR<5>R<6> or CO2R<7>; C2-C4 alkenyl optionally substituted with CN, CONR<5>R<6> or CO2R<7>; C2-C4 alkanoyl optionally substituted with NR<5>R<6>; hydroxy C2-C4 alkyl optionally susbtituted with NR<5>R<6>; (C2-C3 alkoxy)C1-C2 alkyl optionally substituted with OH or NR<5>R<6>; CONR<5>R<6>; CO2R<7>; halo; NR<5>R<6>; NHSO2NR<5>R<6>; NHSO2R<8>; or phenyl or heterocyclyl either of which is optionally substituted with methyl; R<5> and R<6> are each independently H or C1-C4 alkyl, or together with the nitrogen atom to which they are attached from a pyrrolidinyl, piperidino, morpholino, 4-(NR<9>)-piperazinyl or imidazoyl group wherein said group is optionally substituted with methyl or hydroxy; R<7> is H or C1-C4 alkyl; R<8> is C1-C3 alkyl optionally substituted with NR<5>R<6>; and R<9> is H; C1-C3 alkyl optionally substituted with phenyl; hydroxy C2-C3 alkyl; or C1-C4 alkanoyl; are selective cGMP PDE inhibitors useful in the treatment of cardiovascular disorders such as angina, hypertension, heart failure and atherosclerosis.
Patent AU-694966-B2 (AU)
Title: Novel pesticidal composition and bacillus thuringiensis strain
Inventor: LIU CHI-LI
IPC: A01N63/00
Filed: 1995-03-14
Granted: 1998-08-06
Abstract: The invention is related to a novel strain(s) of Bacillus thuringiensis in which essentially all of the pesticidal activity of said strain is in the supernatant of a fermentation of said strain. The strain produces a substance which has activity against an insect pest(s) of the order Coleoptera and which enhances the pesticidal activity of a Bacillus related pesticide. The invention further relates to pesticidal compositions comprising the substance and a pesticidal carrier, or the substance and a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties as well as methods of using the pesticidal compositions to control a pest.
Patent AU-599836-B2 (AU)
Title: A method and apparatus for producing can bodies of a non-circular cross-section
Inventor: ROLLI HANS
IPC: B21D51/26
Filed: 1988-09-28
Granted: 1990-07-26
Abstract: To make can bodies with a non-circular cross-section, preferably with a rectangular cross-section and rounded corners, flat blanks (3) are first of all deformed in a deformation station (5) by means of a plurality of bending tools (20) of the same type to produce in each case a bend, another bend in each case being simultaneously produced on the various blanks (3), which are transported onwards in steps. The bending tool (20) has a shaped part (21) held fixed on the inside and having a curved outer face (22) and furthermore has a roller (24), which is mounted in a mounting body (23) and is under the influence of a spring (26) pressing against the mounting body (23) in order, during the movement brought about by a lifting rod (28) articulated on the mounting body (23), to bend the blank (3) situated between the shaped part (21) and the pressure roller (24) upwards. This is accomplished simultaneously at all the bending tools (20), each provided for one bend, by a moveable part (7) of the deformation device (5) operating as a press. The blank (3) is moved onwards in steps from one bending device (20) to the next, with the result that, after a plurality of working steps, a can body with a rectangular cross-section and rounded corners has been produced, the edges of which are connected in a subsequent welding station by electric resistance welding. 
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Patent AU-696561-B2 (AU)
Title: A process for the preparation of 5,6-dihydroxy-2-amino- 1,2,3,4-tetrahydronaphthalene derivatives
Inventor: CHIESI PAOLO
IPC: C07C213/02
Filed: 1995-04-13
Granted: 1998-09-10
Abstract: A process, and variations thereof, for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalene derivatives of formula (I), wherein R1, R2, R3 can independently be hydrogen or lower alkyl.
Patent AU-721838-B2 (AU)
Title: Flexible, multiple-compartment drug container and method of making and using same
Inventor: BARNEY WARD W
IPC: B31B50/64
Filed: 1997-04-11
Granted: 2000-07-13
Abstract: A method for forming a flexible container (10) for combined storage and administration is described. The method comprising the steps of sealing flexible front and rear sheets (12, 14) together at a common peripheral edge (16); heating the front and rear sheets (12, 14) in a first localised area to form a first peelable seal (24) extending between two sides of the common peripheral edge (16), the first peelable seal (24) separably joining the front and rear sheets (12, 14) to thereby form a first compartment (18) for containing a first product; and heating the front and rear sheets (12, 14) in a second localised area to form a second peelable seal (26) extending between the two sides of the common peripheral edge (16), the second peelable seal separably joining the front and rear sheets (12, 14) to thereby form an outlet compartment (22) and a second compartment (20) for containing a second product, the second compartment (20) being between the outlet compartment (22) and the first compartment (18). For ease of manufacture and filling first and second sacrificial ports (102, 104) are provided which are interposed between the front and rear sheets (12, 14) and are in communication with the first and second compartments (18, 20), respectively; with the first compartment (18) is filled with a first product through a respective sacrificial port (102); the second compartment (20) is filled with a second product through a respective sacrificial port (104); and the seal along the common peripheral edge (16) is completed and the sacrificial ports (102, 104) are removed from the container (10).
Patent AU-690689-B2 (AU)
Title: Improved catalysts for the manufacture of carbon fibrils and methods of use thereof
Inventor: MOY DAVID
IPC: B01J23/76
Filed: 1995-05-12
Granted: 1998-04-30
Abstract: A catalyst for the production of carbon fibrils and a method for the manufacture of such a catalyst comprising contacting a fibril-forming catalyst or precursors of a fibril-forming catalyst with an effective amount of a surfactant and/or polyol. The improved carbon fibrils or carbon fibril aggregates produced using the catalyst are free of a continuous carbon thermal overcoat, with graphitic layers substantially parallel to the fibril axis, and have a substantially constant diameter from about 1.0 to 100 nanometers. The improved carbon fibrils possess enhanced dispersion in composite materials and provide enhanced electrical conductivity in those materials.
Patent AU-729512-B2 (AU)
Title: Control process and device for the operation of a system for treating the surface of a solid running substrate
Inventor: LAGRANGE GILLES
IPC: C23C16/50
Filed: 1997-06-20
Granted: 2001-02-01
Abstract: The assembly to treat the surface of a moving polymer material, through the electrical discharge of a barrier dielectric in a controlled gas atmosphere, has a data processing unit (10) to take data on the speed of material movement with outputs to send command signals to the control (14) for the gas feed (7) and the electrical supply (8) control (15). They determine the vol. of gas feed (7) and/or level of power supply (8), as a function of the speed of material (3) travel through the assembly (2), to match the processing action to the movement speed. Also claimed is an operation where the speed of substrate travel is measured through the assembly. The control system sets the vol. of gas delivered (7) and/or the power level of the electrical supply (8) according to the measured substrate speed. Preferably The data processing unit (10) outputs are linked to the controls (18,19) for gas extraction (9), to set the extraction rate in relation to the speed of substrate (3) travel. The gas extraction system has a main exhaust (16) at the entry into the assembly (2) and a second exhaust (17) is at the assembly outlet. The data processing unit (10) is linked to the controls (18, 19) for both exhausts. The data processing unit (10) can simulate and/or use a model for the operation of the assembly (2) to set the parameters for the surface treatment of the substrate (3) passing through, for a given effect at the outlet. The unit (10) is linked to a remote control unit by data links (20). The unit (10) has at least one interface (21, 22) for a manual input.
Patent AU-622630-B2 (AU)
Title: D-cycloserine and its prodrugs as cognitive enhancers
Inventor: CORDI ALEX A
IPC: A61K31/42
Filed: 1988-11-29
Granted: 1992-04-16
Abstract: The compound D-cycloserine and its prodrug compounds are described as having cognitive-enhancing activity.
Patent AU-669489-B2 (AU)
Title: Method of synthesizing diverse collections of oligomers
Inventor: DOWER WILLIAM J
IPC: C07K5/00
Filed: 1992-09-16
Granted: 1996-06-13
Abstract: The invention provides a process for preparing a new pharmaceutical drug or diagnostic reagent, which includes the step of screening against a ligand or receptor a library of different synthetic compounds, which compounds are obtainable by synthesis in a component by component fashion which links each compound to one or more identifier tags which enable subsequent identification of reactions through which said components were incorporated and consequent deductive structural identification of said members. The same basic process can be used to provide new pesticides or herbicides.
Patent AU-635197-B2 (AU)
Title: Antimicrobial device and method
IPC: A61L29/00
Filed: 1988-11-23
Granted: 1993-03-18
Abstract: A medical device made from a material capable of being implanted in living tissue or transcutaneously inserted therein or of long term in-dwelling therein, which exhibits persistent antimicrobial activity in use, and containing a body of a synthetic or naturally occurring material having side surfaces and being capable of being swelled by penetration of a swelling agent and which has been subjected to such a swelling agent which contains completely dissolved therein at least one antimicrobial agent as a solute, the surfaces being contacted by such swelling agent for a sufficient period of time to promote swelling of the matrix of a body of material and thereby permit diffusion and migration of the solution containing the selected antimicrobial agent solute into the interstitial spaces of the body of material at the molecular level by the action of the swelling agent within the body of material, and the solvent being capable of being removed from the solute in the body of material by evaporation and after removal of the solvent the body of material being capable of returning substantially to its original size and shape with the antimicrobial agent substantially uniformly deposited therein for subsequent continuous migration to and diffusion through the surfaces.
Patent AU-615979-B2 (AU)
Title: Intercommunication method and system thereof
Inventor: ISHIDA NAOMI
IPC: H04L12/40
Filed: 1989-01-19
Granted: 1991-10-17
Abstract: To control a plurality of apparatuses (6a-6z), the apparatuses and a master control unit (2) having a communication unit are all connected for intercommunication in series through communication lines (10). One of the communication unit is used for exchanging messages between the master control unit and the apparatuses. Messages can transfer from one apparatus to another one in sequence. In another embodiment, the last apparatus is further connected with another communication unit of the master control unit, making a looped communication circuit. Therefore, messages sent out from one of the communication units of the master control unit can be received by the other communication unit to monitor the intercommunication. If a communication line is disconnected, messages can be also sent from another communication unit of the master control unit in reverse direction, making it possible to communicate with all of the apparatuses.
Patent AU-712562-B2 (AU)
Title: Process and apparatus for gravimetric test gas production by means of re-weighing
Inventor: SCHON HELMUT
IPC: F17C5/00
Filed: 1997-05-05
Granted: 1999-11-11
Abstract: The invention relates to a process and device for gravimetric test gas production by means of reweighing. In order fully to automate test gas production it is proposed to weigh an evacuated gas container fitted with a controllable valve on a balance, to connect a gas supply to the valve via a controllable adjuster fitted to the balance, to open the controllable valve automatically, to fill the first test gas component. The quantity allowed in is automatically checked by weighing, and after the required quantity has been filled the controllable valve is closed, the connection between the gas supply and the controllable valve is released by means of the adjuster, the gas supply is separated from the balance automatically and the gas container reweighed. These steps are suitably repeated for each test gas component to be fed into the gas container.
Patent AU-657010-B2 (AU)
Title: Roller, especially for application in a printing machine
Inventor: VONK LEO
IPC: B65G39/02
Filed: 1992-11-26
Granted: 1995-02-23
Abstract: The invention relates to a roller such as for application in the inking machinery of a printing machine, comprising a central shaft (1) to be journalled in the printing machine and a shell (2) extending concentrically around said shaft (1). Essentially the shell (2) and shaft (1) are made of plastic material, whereas at both ends of the shaft (1) respective metal jackets (10) are provided extending up to the respective frontal ends of the shaft (1). Preferably the frontal ends of the shell (15) too are provided with metal jacket-shaped parts (22). <IMAGE>
Patent AU-558783-B2 (AU)
Title: Apparatus for mixing and metering flowable solid materials
Inventor: MATHIS PAUL
IPC: B65G65/48
Filed: 1984-07-16
Granted: 1987-02-05
Abstract: The centrally located outlet in the bottom portion of a silo for a flowable solid building material or fertilizer discharges directly into a first chamber of a mixing unit having a vertical shaft which is coaxial with the outlet and rotates one or more first tools in the first chamber to uniformly distribute the inflowing material and to reduce its tendency to become separated into two or more ingredients. The thus pretreated material descends into a second chamber and into the range of one or more rotating second tools which are driven by the shaft and intermix the material with one or more liquids before the finished product enters an evacuating pump which conveys it to one or more locations of use or to further processing units. The utilization of a vertical shaft and of parts which rotate about one or more vertical axes reduces the wear and prolongs the useful life of such moving parts. The housing of the mixing unit is attached directly to the silo and is pivotable to and from a position of register of its first chamber with the outlet.
Patent AU-691327-B2 (AU)
Title: Morpholine derivatives and their use as therapeutic agents
Inventor: HARRISON TIMOTHY
IPC: A61P1/08
Filed: 1995-08-07
Granted: 1998-05-14
Abstract: PCT No. PCT/GB95/01868 Sec. 371 Date Feb. 13, 1997 Sec. 102(e) Date Feb. 13, 1997 PCT Filed Aug. 7, 1995 PCT Pub. No. WO96/05181 PCT Pub. Date Feb. 22, 1996The present invention relates to compounds of formula (I)    <IMAGE>  (I)  wherein X is -NR6R7 or C- or N-linked imidazolyl; Y is hydrogen or C1-4alkyl optionally substituted by hydroxy; R1, R2, R3, R4 and R5 are selected from a variety of suitable aromatic substituents; R6 is hydrogen, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-4alkyl, phenyl, or C2-4alkyl substituted by C1-4alkoxy or hydroxy; R7 is hydrogen, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkyl C1-4alkyl, phenyl, or C2-4alkyl substituted by one or two of C1-4alkoxy, hydroxy or a 4, 5 or 6 membered heteroaliphatic ring containing one or two heteroatoms selected from N, O and S; or NR6R7 is a saturated or partially saturated heterocyclic ring of 4 to 7 ring atoms, optionally containing one of O, S, NR8, S(O) or S(O)2 and optionally substituted by one or two of hydroxy1-4alkyl, C1-4alkoxy C1-4alkyl, oxo, CORa or CO2Ra; or NR6R7 forms a non-aromatic azabicyclic ring system of 6 to 12 ring atoms; and R9a and R9b are each independently hydrogen or C1-4alkyl, or R9a and R9b are joined so, together with the carbon atoms to which they are attached, there is formed a C5-7ring; or a pharmaceutically acceptable salt thereof. The compounds are of particular use in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
Patent AU-684220-B2 (AU)
Title: Recombinant adenovirus comprising a chimeric penton base protein
Inventor: WICKHAM THOMAS J
IPC: C12N15/87
Filed: 1995-08-07
Granted: 1997-12-04
Abstract: A recombinant adenovirus comprising a chimeric penton base protein, wherein an RGD amino acid sequence is deleted from the penton base protein, a method of gene therapy involving the use of such adenovirus, and adenoviral transfer vectors for the generation of such recombinant adenovirus are provided.
Patent AU-615044-B2 (AU)
Title: Bainitic core grinding rod
Inventor: ARNETT CHARLES R
IPC: C21D9/36
Filed: 1989-04-05
Granted: 1991-09-19
Abstract: A carbon or alloy steel heat treated grinding rod having improved wear resistance and breaking resistance for use in a rotating grinding mill. The surface of the rod has a martensitic microstructure having a hardness of at least HRC 55. The core of the rod has a bainitic microstructure having a hardness of at least HRC 40. A preferred rod composition includes at least .7% carbon, at least .25% of molybdenum, at least .25% chromium, less than .7% manganese, the balance iron and unavoidable impurities, all percentages by weight.
Patent AU-612837-B2 (AU)
Title: Method for production of human tissue type plasminogen activator
Inventor: MIYAHARA SHOICHIRO
IPC: C12N9/72
Filed: 1989-05-17
Granted: 1991-07-18
Abstract: A method for the production of human tissue type plasminogen activator (tPA) using cells includes use of a p-aminomethyl benzoic acid derivative to supplement a cell culture medium or a tPA producing medium and further an increase of osmotic pressure in the medium to 350 milliosmoles or more per litre. The method can produce single-chain tPA in a high concentration and with a relatively small amount of double-chain tPA in the medium.
Patent AU-569920-B2 (AU)
Title: Administration of gangliosides by inhalation
Inventor: VALLE FRANCESCO DELLA
IPC: C07H19/01
Filed: 1984-11-07
Granted: 1988-02-25
Abstract: The present invention relates to a device or kit and a method for the inhalation administration of gangliosides and inner ester ganglioside derivatives useful for the treatment of various nervous disorders, such as those resulting from accidents or diseases which have damaged the nervous tissue.
Patent AU-700797-B2 (AU)
Title: Transfer of molecules into the cytosol of cells
Inventor: BERG KRISTIAN
IPC: A61K41/00
Filed: 1995-09-04
Granted: 1999-01-14
Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.