baber/WOPTO huggingface dataset:
Patent CR-20190352-A (CR)
Inventor: BECKER ACHIM
IPC: A61P5/16
Filed: 2018-02-02
Abstract: Se describe un agente terapéutico oral tiroidal que contiene levotiroxina o sus sales farmacéuticamente aceptables como un ingrediente activo en combinación con al menos un antioxidante y al menos un adsorbente, en donde la proporción de ingrediente activo: antioxidante: adsorbente en peso-% es 1: 1 : 5 a 1: 50: 100.The invention relates to an oral thyroid therapeutic agent, containing levothyroxine or its pharmaceutically compatible salts as active agents, in combination with at least one anti-oxidant and at least one absorption agent, wherein the weight percentage of active agents: anti-oxidants: adsorption agent is 1 : 1 : 5 - 1 : 50 : 100.
Patent CR-20210210-A (CR)
Title: Cyclodextrin-based formulation of a bcl-2 inhibitor
Inventor: CHEMIN CAROLINE
IPC: A61K47/40
Filed: 2019-10-30
Abstract: The invention relates to a pharmaceutical composition comprising 5-(5-chloro-2-{[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-N-(5-cyano-1,2-dimethyl-1H-pyrrol-3-yl)-N-(4-hydroxyphenyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide, referred to herein as 'Compound A', or a pharmaceutically acceptable salt thereof, and a cyclodextrin. More specifically, the invention relates to a solid pharmaceutical composition comprising Compound A and a cyclodextrin, and a pharmaceutical composition for parenteral administration prepared by dissolving this solid pharmaceutical composition. Furthermore, the invention relates to the use of such compositions for the treatment of cancer.
Patent EC-SP003695-A (EC)
Title: Produccion natural bajo sistema integral de manejo en el cultivo de camarones pronasim
Inventor: SCHUPPENER HEINRICH
Filed: 2000-10-06
Abstract: aqua-biotecnología para mejorar el crecimiento, vigor, desarrollo, productividad y resistencia natural del cultivo del camarón contra factores adversos en la producción acuicola.
Patent EC-SP077329-A (EC)
Title: Un sistema y metodo para generar una imagen y un codigo de barras combinados
Inventor: LUBOW ALLEN
IPC: G06K7/10
Filed: 2007-03-20
Abstract: Se proporciona un sistema y un método que incluye generar un símbolo de código de barras y una imagen combinados, que es legible por un dispositivo de escáner de código de barras. El sistema incluye un programa de computación que proporciona una imagen y un símbolo de código de barras y combina el símbolo de código de barras con la imagen, de tal forma que el símbolo de código de barras es legible por el dispositivo de escáner de código de barras. El sistema procesa la imagen y el símbolo de código de barras comparando las propiedades correspondientes a la imagen, el símbolo de código de barras (por ejemplo valores de color), y las propiedades correspondientes a los valores de sensibilidad del escáner de código de barras asociados con el dispositivo de escáner de código de barras. El símbolo de código de barras procesado que está combinado con la imagen procesada es legible mediante el dispositivo de escáner del código de barras.
Patent EC-SP099739-A (EC)
Title: Sistema de Construcción de paredes, columnas y vigas con o sin mortero usando Bloques encajables para Paredes y Bloques encajables para columnas y vigas.
IPC: E04B2/24
Filed: 2009-11-17
Abstract: RESUMENEste invento es un sistema que abarata los costos de construcción de paredes, columnas y vigas ensamblando elementos que los denominamos Bloques encajables para Columna y para pared. Estos bloques están, provistos en sus caras, de bordes y/o canales o muescas, que al ensamblar sucesiva y selectivamente la cara provista de borde, en la cara provista de muesca o canal, del bloque contiguo se auto alinean automáticamente en el sentido vertical y horizontal sin tener que usar una guía horizontal o plomada, facilitando que la construcción de paredes y columnas lo pueda hacer cualquier persona aunque no tenga pericia de albañil, solventando en parte el problema de la vivienda especialmente entre las clase económica menos favorecidas. El ensamble puede realizarse con o sin aditivo o mortero, el mismo que se lo puede proveer al final, cuando la pared o columna determinada se haya ensamblado en seco, es decir sin mortero
Patent FI-20120287-A (FI)
Inventor: SIPPONEN PENTTI
IPC: B27K3/34
Filed: 2012-08-29
Abstract: An aqueous antimicrobial composition comprising coniferous resin acids a dispersing agent and an aqueous medium, a method for its preparation and its use as an antimicrobial agent in medical and non-medical field are provided.
Patent FR-1172527-A (FR)
IPC: C08L27/12
Filed: 1956-05-22
Granted: 1959-02-11
Abstract: 849,837. Coated metallic fabrics. COMMISSARIAT A L'ENERGIE ATOMIQUE. May 16, 1957 [May 22, 1956], No. 15669/57. Class 140. A porous membrane constituted by a corrosion-resisting metallic fabric and a porous layer of a fluorohydrocarbon polymer, chlorofluorohydrocarbon polymer or a halogenated hydrocarbon grease or wax, embedding said fabric is produced by forming an emulsion of at least one of the polymers, grease or wax, treating the emulsion with a coagulant to flocculate it into a moist paste, coating the metallic fabric with said paste, fixing said layer and eliminating the coagulant therefrom. The layer may be fixed by passage between the rollers of a rolling- machine, and then dried in air to eliminate the coagulant. After drying the coated fabric may be heated at a temperature averaging 300‹ C. for several hours, cooled, washed with alcohol and again passed through a rolling-machine and dried in air. The coating may contain polytetrafluoroethylene or polytrifluoromonochloro ethylene, and also corrosion-resisting powders preferably selected from nickel, calcium fluoride and titanium dioxide which are added to the emulsion. A non-ionic wetting-substance, e.g. an alkylaryl polyether alcohol or a polyethylene glycol ether of an alkylated phenol, may also be added to the emulsion. The corrosion-resistant metallic fabric may be of nickel, silver, or a metal coated with nickel or silver. The coagulant may be selected from methyl, ethyl, isopropyl, butyl, isobutyl, and isoamyl alcohols, cyclohexanol, acetone and acetic acid.
Patent GB-1051846-A (GB)
IPC: B60L11/18
Abstract: 1,051,846. Control of D.C. motors. LICENTIA PATENT - VERWALTUNGS - G.m.b.H. Sept. 5, 1963 [Sept. 5, 1962], No. 35130/63. Movement of a brake pedal 1 or other actuator of a battery-electric vehicle progressively provides regenerative braking and additional mechanical braking. The braking circuit shown comprises a battery 7, diode 8 and a rectifier valve 9, in parallel with the drive motor, which is rendered alternately conducting and non- conducting by a semi-conductor control device 4 with a pulse frequency dependent on an actual current input list and a desired braking input ISOLL from potentiometer 3. When valve 9 is conducting the inductance of the motor is charged and when the valve 9 becomes non- conducting, the energy in the inductance is discharged through diode 8 to the battery 7.
Patent GB-1052951-A (GB)
IPC: C07C49/747
Abstract: 1,052,951. Herbicidal compositions. IMPERIAL CHEMICAL INDUSTRIES Ltd. June 21, 1963 [March 21, 1962], No. 10885/62. Heading A5E. [Also in Division C2] Herbicidal compositions comprise as active ingredient a compound of formula: wherein R stands for a hydrogen atom or an aliphatic hydrocarbon radical containing from 1 to 7 carbon atoms, R 1  is an aliphatic hydrocarbon radical containing from 1 to 7 carbon atoms, R 2  and R 3  are phenyl radicals which may be linked by a chemical bond or phenyl radicals substituted with one or more alkyl, alkoxy, hydroxyl or halogen radicals and a carrier therefor comprising a solid inert diluent or a liquid diluent containing a surface active agent. Specified forms are powders and aqueous dispersions.
Patent GB-1053914-A (GB)
IPC: F16H47/08
Abstract: 1,053,914. Hydraulic torque converters; change-speed control. FORD MOTOR CO. Ltd. Jan. 27, 1965 [March 16, 1964], No. 3478/65. Headings F2C and F2D. In an hydrodynamic torque converter comprising an I.C. engine-connected impeller 43, a turbine 42 and a reactor 56 reacting on a oneway roller detent 68, a valve means comprising ball valves 72 the bodies of which are fast with the reactor, is open when the reactor is stationary during the torque conversion condition and centrifugally closed when the reactor rotates during the converter coupling condition, such closure effecting in a passage 94 a pressure build-up which is used as a signal to initiat shifts in a motor vehicle automatic changespeed planetary gear. In the change-speed control system a pump P, one of the elements 32 of which is connected to the engine driven impeller, feeds a pressure regulator 106 maintaining a predetermined operating pressure in a main line 108. The regulator 106 also distributes a regulated lower pressure which is fed through a line 110, a passage 96, and radial grooves in a thrust washer 98 to the converter torus circuit, the return from which is through openings in a spacer 70, axial grooves in a bushing 100, and an annular passage 102. Main line pressure in 108 is fed to a reducing valve 112 which in turn feeds the signal line 94 the outlet of which when the valve means 72 is open supplements the normal converter feed. Main line pressure in 108 is also fed to shift valves 116 which selectively distribute pressure to the gear friction clutch and brake servomotors and are responsive to the pressure signal in the line 94. As the converter assumes its coupling condition following initial acceleration from a standing start, the signal in the line 94 initiates an upshift in the gear. Such an upshift may be accompanied by a return of the converter to its torque conversion condition for further torque multiplication during the acceleration period, the stationing of the reactor during such a return effecting opening of the valve means 72 and a drop in pressure in the line 94. In a threespeed gear the pressure signal in the line 94 is used for both upshifts, a second signal being obtained as the converter reaches its coupling point for a second time. In order to distinguish the two separate signals in the line 94, a timing valve assembly 120 responsive to a torque demand sensitive signal in a line 122 is used. In a two-speed gear the timing valve assembly prevents downshift when the converter returns to torque conversion following an upshift, and in a three-speed gear it in addition distributes the two signals to different portions of the shift valve assembly. To delay shift valve response, an accumulator 126 may be used to delay pressure build-up in the line 94. The main line pressure regulator 106, the reducing valve 112, the accumulator 126 and the shift valves 116 may be rendered responsive to a torque demand (throttle variable) signal. The line 94 is also connected to the regulator 106 by a passage 119 to reduce main line pressure when the torque converter is in coupling condition.
Patent GB-1054605-A (GB)
IPC: C07C275/34
Abstract: 1,054,605. Photo-sensitive materials. KALLE A.G. July 30, 1965 [Aug.1, 1964], No. 32767/65. Heading G2C. [Also in Division C2] A light-sensitive material comprises a support coated with a layer containing a salt of a pdiazodiphenylamine or a morpholine derivative thereof and an azo coupler of formula wherein R is an alkyl group with 1-3 carbon atoms, R' is methyl or alkoxy group with 1-3 carbon atoms, R" is alkyl with 1-3 carbon atoms or a phenyl, benzyl or amino group and X is carbonyl, thiocarbonyl, iminocarbonyl or a sulphonyl group. The support may be coated with a silica layer before applying the lightsensitive layer.
Patent GB-1054794-A (GB)
IPC: H05B41/24
Abstract: 1,054,794. Supply systems for monochromatic light sources. CSF-COMPAGNIE GENERALE DE TELEGRAPHIE SANS FIL. July 23, 1963 [July 31. 1962], No. 29202/63. Heading H2H. A monochromatic light source comprises a glass tube 1 filled with a mixture of an alkaline vapour and argon, the ends of the tube being surrounded by oppositely connected identical windings 2, 3 connected in a series circuit with a variable capacitor 12, the assembly being supplied with a high frequency alternating voltage by a generator 10, the output of the generator being connected across one turn of the winding 2. The capacitor 12 is provided to allow the series circuit 2, 12, 3 to be tuned to resonance at the frequency of the generator 10 whereby the circuit 2, 12, 3 presents a substantially resistive impedance to the generator and thus the light output is substantially constant. In a second embodiment the generator 10 is shown as a thermionic valve oscillator with a feedback to the oscillator provided from the circuit 2, 12, 3 to further improve the constancy of the light output.
Patent GB-1084319-A (GB)
IPC: G21C13/067
Abstract: 1,084,319. Reactors. ENGLISH ELECTRIC CO. Ltd. Nov. 11, 1964 [Nov. 1, 1963], No. 43167/63. Heading G6C. [Also in Division F2] Means for closing a cylindrical pipe 10 containing fluid under pressure in a nuclear reactor includes a plurality of radial supports 22 on the wall of the pipe, a cylindrical plug 12 with a rotatable locking ring 20 which has radial lugs 21 for engaging the supports 22 to restrain the plug from movement when it is under pressure, axial passages at one end of the pipe between the supports 22 so that when the member 20 is rotated it can be moved clear of the supports to permit withdrawal of the plug and a lifting ring 18 which supports the ring 20 axially with respect to the plug. The plug has a gas seal 13 at its lower end and the ring 20 is normally held against the supports 22 by gas pressure; the plug has a shoulder 14 which rests on a supporting ring 17 on the pipe if the pressure is relaxed. A key 15 below the shoulder 14 engages in a vertical slot 16 to locate and prevent rotation of the plug in the pipe in the latter position. Pegs 23 engage in slots in the ring 20 to limit its rotation about the plug. The rings 18 and 20 have longitudinal slots 25 and 26 which are normally held in alignment by a latch 27 having a finger which is urged by a spring 28 into a slot 33 in the ring 18 whilst a segmental portion of the latch enters a slot 32 to hold the ring 20 against rotation. A projection 51 on one of the lugs 21 enters a corresponding recess 52 in one of the supports 22 so that even if it is unlatched, the ring 20 cannot be rotated before the plug has moved longitudinally relative to the pipe (Fig. 5). To remove the plug from the pipe a machine (not shown) applies a gas pressure to its head at least equal to that in the pipe so that the plug falls until the shoulder 14 rests on the ring 17. A cylindrical lifting head 40 (Fig. 4) is then lowered into the annular space between the plug and the end of the pipe so that lifting lugs 42 thereon, followed by fingers 44 on an indexing sleeve 43, enter the aligned slots 25, 26. One of the lugs 42 engages the latch 27 and releases it from the ring 20. The lugs 42 are then rotated relative to the fingers 434 so that the former push on the side of the slots 25 and rotate the locking ring 20 until it is free from the supports and each lug is positioned under an unslotted part of the lifting ring 18. The plug can then be lifted out of the pipe.
Patent GB-1143561-A (GB)
IPC: C08G63/16
Abstract: 1,143,561. Polyurethanes. HENKEL & CIE G.m.b.H. 13 July, 1967 [14 July, 1966], No. 32186/67. Headings C3C and C3R. [Also in Division B2] Polyurethanes are prepared by reacting an organic polyisocyanate with a liquid polyester containing two hydroxyl groups, having an upper limit of its solidification range not exceeding 18‹ C., which is made from adipic acid and a mixture of (a) 60 to 90% by weight of at least two unbranched diols with terminal OH groups and having 2 to 8 carbon atoms, 10 to 80% being butanediol-1,4 and/or hexanediol-1,6 and (b) 40 to 10% by weight of a branched diol having 3 to 7 carbon atoms. Specific polyesters exemplified are reaction products of adipic acid, hexanediol-1,6, neopentylglycol and (I) propanediol-1,3, (II)pentanediol-1,5,(III)as(II) and (IV) diethylene glycol. Chain lengthening agents such as glycols, diamines and/or water may be included in the reaction mixture as may tertiary amines and/or organometallic compounds as catalysts. Foaming agents and fillers may also be incorporated in the reaction mixture.
Patent GB-1227030-A (GB)
IPC: A61B5/022
Filed: 1968-04-10
Abstract: 1,227,030. Sphygmometers. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. 10 April, 1968 [13 April, 1967], No. 17247/ 68. Heading ASK. A sphygmometer, which may be used to measure the blood pressure by noting the change in electrical conductivity of the body at systol or diastol, comprises an inflatable pressure cuff 4 having three body contacting electrodes 1, 2, 3 which are connected to a differential amplifier 12 the output from the amplifier 12 being connected to a discriminator 13 which operates means for measuring the pressure in the cuff when the signal applied from the amplifier to the discriminator falls below an adjustable threshold level. As shown, the cuff 4 has an inflation hose 5 and is connected to systol and diastol pressure gauges 29, 30. A high frequency current generator 18-23 applies pulses (a few mA. at 100 KHz) through a tuned circuit 24-26 to the body electrodes 1, 2 and, as the artery opens on gradual reduction of pressure within the cuff, pulses dependant on the impedance variations between the electrodes 2, 3 are amplified at 10 and 14 and pass through a gate circuit 17 and relay 27 to close a valve 28 so that the gauge 29 records the systolic pressure. When, after further reduction of pressure within the cuff, the artery remains open between heartbeats a phase difference between voltage pulses from the electrodes 1, 3 and 2, 3 disappears and the output from the differential amplifier decreases below the threshold voltage of a discriminator device 13 so that a gate circuit 16 and relay 32 close a valve 31 to record the diastolic pressure at the gauge 30. The central electrode 3 is said to be positioned alongside the centre of the pressure cuff on the side remote from the inlet of the blood stream, the outer electrodes 1, 2 are equally spaced either side of the central electrode.
Patent GB-1231407-A (GB)
IPC: C08L61/20
Filed: 1968-09-24
Abstract: 1,231,407. Coated film. KALLE A.G. 24 Sept., 1968 [25 Sept., 1967], No. 45301/68. Heading B2E. [Also in Division G2] A transparent drawing material comprises a support of polyester film and a drawing layer containing as pigment silica, calcined alumina, and/or aluminium silicate and as a binder a hardened mixture of polyvinyl alcohol, a urea/ formaldehyde or melamine/formaldehyde precondensate and an acrylic ester copolymer. The initially water-soluble polyvinyl alcohol is cross-linked by the aldehyde condensation resin. The copolymer is obtained by polymerisation of suitable monomers including methyl, ethyl, isopropyl, n-butyl, isobutyl acrylate, methyl methacrylate, methyl ethacrylate and butyl methacrylate. Suitable comonomers are styrene, alpha-alkyl styrenes, vinyl toluenes, vinyl chloride, vinyl ether, vinyl ester and acrylic acids. Mixtures of pigments of different grain size can be used. Stretched and heat-set polyester films are suitable supports, the preferred polyesters being from terephthalic acid and ethylene glycol, copolyesters of these monomers with other dicarboxylic acids, e.g. isophthalic acid and other di- or polyhydric alcohols, e.g. 1, 3-propane diol, 1, 4- butane diol, and neopentyl glycol also being used. The drawing materials may be processed to give light-sensitive reproduction materials, e.g. by providing them on the side opposite to the drawing layer with a light-sensitive reproduction layer. The drawing layer may also be sensitised by diffusion sensitisation with solutions of e.g. diazo-type mixtures. The drawing material may have an adhesive layer between the support and the drawing layer. The products do not exhibit any curling tendency. In Example I a biaxially stretched and heat-set polyethylene terephthalate film was immersed in a solution comprising 110 grammes trichloroacetic acid, 10 grammes polyvinyl alcohol 1.5 grammes anionic and non-ionic wetting agents, 890 grammes water, and dried to produce an adhesive layer. An aqueous dispersion consisting of polyvinyl alcohol having 12% acetyl group content, a partially etherified melamine/formaldehyde condensate, and a copolymer of 66% methyl acrylate, 22% vinyl isobutyl ether, and 12% styrene, and aluminium silicate pigment, citric acid, non-ionic and anionic wetting agents was poured thereon and dried.
Patent GB-1233625-A (GB)
IPC: F16D65/22
Filed: 1969-02-24
Abstract: 1.233,625. Internal-shoe drum brakes. HEEMAF S.K.A.-MOTORENWERK A.G. 24 Feb., 1939 [1 March, 1968], No. 9773/69. Heading F2E. An electromagnetically releasable brake comprises a brake drum, a concentric annular magnetic body 2, circumferentially extending leafsprings 13 carrying on their free ends magnetic armatures 15 and brake shoes 16, means 7 which limit the movement of the shoes and means attaching the longitudinally central regions of the springs and the stroke limiting means to the magnetic body. The drum rotates and the body 2 containing a coil in a groove 3 is fixed. The brakes can also be retracted by a steel cable 32 in a groove 31 in the shoes. The ends of the cable extend over a rounded portion 33b of means 7 and are attached to the ends of a U-shaped member 34 which is moved axially to release the brakes.
Patent GB-1234543-A (GB)
IPC: C07D213/61
Filed: 1969-02-25
Abstract: 1,234,543. Fluoropyridines. IMPERIAL CHEMICAL INDUSTRIES Ltd. 2 Jan., 1970 [25 Feb., 1969], No. 9953/69. Heading C2C. Fluoropyridines are prepared by replacement of chlorine by fluorine by reaction with hydrogen fluoride vapour at elevated temperature using as catalyst an oxide or fluoride of aluminium or chromium. A specified catalyst is black chromium oxide mixed with graphite. Fixed or fluidized beds may be used. Specified products are 2 - fluoro - 3,4,5,6 - tetrachloropyridine, 2,6 - difluoro - 3,4,5 - trichloropyridine and 2,4,6 - trifluoro - 3,4 - dichloropyridine.
Patent GB-1257225-A (GB)
IPC: C07F7/30
Filed: 1969-03-31
Abstract: 1,257,225. Medicines: organo-germanium compounds. DAIICHI , YAKUHIN SANGYO K.K. 31 March, 1969 [29 March, 1968], No. 16678/69. Heading A5B. [Also in Division C2] A pharmaceutical composition comprises an organo-germanium tumour-retarding agent of the formula I:  in which R is a divalent alkylene radical and R<SP>1</SP> and R<SP>2</SP> are both hydroxyl groups or both amino groups, in association with a pharmaceutical carrier or diluent. The composition preferably comprises an injectable aqueous solution.