baber/WOPTO huggingface dataset:
Patent CA-2451919-A1 (CA)
Inventor: BADER JOEL S
IPC: C12Q1/68
Filed: 2002-08-09
Abstract: Disclosed herein is a nucleic acid sequence that encodes a novel polypeptide . Also disclosed is a polypeptide encoded by the nucleic acid sequence , and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving this novel human nucleic acid and protein. The invention also provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.
Patent CA-2454407-A1 (CA)
Title: A bending-restricting anchoring arrangement and an anchored flexible pipe structure
Inventor: PEDERSEN TOMMY
IPC: F16L1/20
Filed: 2002-08-05
Abstract: A bending-restricting anchoring arrangement for anchoring a flexible pipe (1a,1b,1c) for the transport of a fluid between a seabe d (8) and a sea surface consists of first (2) and second (3) holding sleeves, which, spaced from each other, are adapted to hold a section of the flexible pipe near the seabed. The first holding sleeve (2) is secured via a rigid connecting membe r (5) to a fixed point on the seabed, while the second holding sleeve (3) is movable in a well-defined manner relative to the first connecting sleeve. In an embodiment, the second holding sleeve (3) is secured to a support (9) movable on the seabed. The first and second holding sleeves are connected to each other by means of a mechanical coupling (11) which may be formed by a plurality of rigid members (5, 16, 17, 18), which maintain a fixed distance between the holding sleeves (2, 3) and thereby the geometry of the pipe section disposed between the holding sleeves, in several different ways, via connections between the first and second holding sleeves and/or via connections between their respective rigid connecting mem bers. The inventio n ensures that the forces acting on the flexible pipe because of sea currents, tensile stresses, etc. which occur because of buoyancy when the reinforced pipe is immersed into water, or because of tensile forces that occur because of the use of floating members, are absorbed in the most optimum manner and without any risk of overbending of the section of the pipe (1b) between the connection sleeves (2, 3).
Patent CA-2454436-A1 (CA)
Inventor: PITZEN JAMES F
IPC: B24D7/00
Filed: 2002-07-08
Abstract: A universal abrasive article (100) adapted to mount on a mounting surface of a sanding machine having a plurality of dust extraction holes that define an open area. The abrasive article includes a plurality of discrete apertures (110) that are sized and positioned so as to expose a majority of the open area of the dust extraction holes (130, 135) independent of the angular orientation of the abrasive article when the abrasive article is in registration with the mounting surface. The discrete apertures may include elongated, arcuate slots that may be symmetrically positioned about a center point of the abrasive article. In one embodiment, the discrete apertures may include seven arcuate slots (210). These embodiments also include sufficient abrasive material to provide adequate sanding cut rate and structural integrity during use and removal.
Patent CA-2455209-A1 (CA)
Title: High tenacity polyethylene-2,6-naphthalate fibers having excellent processability
Inventor: KIM YOUNG-JO
IPC: C08L67/02
Filed: 2004-01-14
Abstract: The present invention relates to a high tenacity polyethylene naphthala te fiber containing a silica compound. This fiber is produced by a method comprising the steps of: (A) melt-spinning a solid phase-polymerized polyethylene-2,6-naphthalate chip containing ethylene-2,6-naphthalate units at more than 85 mole% and a silica compound and having an intrinsic viscosity o f 0.70-1.20, to produce a melt-spun yarn; (B) passing the melt-spun yarn throu gh a retarded cooling zone and a cooling zone to solidify the yarn; (C) withdrawi ng the yarn at such a speed that the undrawn yarn has a birefringence of 0.001-0.1; and (D) subjecting the undrawn yarn to multi-stage drawing at a total draw ratio of at least 1.5 and a drawing temperature of 50-250.degree.C. The polyethylene naphthalate fiber has improved physical properties, such as high tenacity, and a dipped cord produced from this fiber has excellent dimensional stability and tenacity su ch that it can be advantageously employed as a reinforcement material of rubber products.
Patent CA-2455235-A1 (CA)
Inventor: GUO ZHIQIANG
IPC: A61P15/18
Filed: 2002-08-02
Abstract: Cette invention a trait à des antagonistes du récepteur de la GnRH, se révélant des plus utiles pour traiter divers états pathologiques en relation avec les hormones sexuelles, tant chez l'homme que chez la femme. Les composés selon l'invention correspondent à la structure suivante : Dans cette formule, R¿1?, R¿2?, R¿3a?, R¿3b?, R¿4?, R¿5? et n sont tels que définis dans le descriptif, notamment des stéréo-isomères, des promédicaments et leurs sels acceptables du point de vue pharmaceutique. Il est également question de compositions renfermant un composé selon l'invention, associé à un excipient acceptable du point de vue pharmaceutique. L'invention concerne, en outre, des méthodes d'utilisation de ces composés à des fins antagonistes à l'encontre de l'hormone de libération des gonadotrophines et ce, chez des patients nécessitant un tel traitement.
Patent CA-2456944-A1 (CA)
Inventor: VALLON EMMANUEL
IPC: B25C1/18
Filed: 2004-02-04
Abstract: Each fastener comprises a shank pointed at one end and bearing a head at the other end, the fasteners are engaged respectively via their shanks in guide pegs (11) joined together into a string (20). At least one of the guide pegs at the end of the string (11', 11") comprises support means (14) designed to prevent it from tilting as it is transferred from the loading device into the apparatus.
Patent CA-2458710-A1 (CA)
Inventor: CHIPROOT AVI
IPC: F16L55/17
Filed: 2004-02-25
Abstract: A pipe clamp or coupling for pipes repair or for sealing relationship has a metal clamping band to surround the pipes, and a flexible inner sleeve disposed inside the clamping band. A reinforcing material is bonded to the flexible inner sleeve or embedded therein to inhibit axial expansion thereof when the inner sleeve is under compression between the pipes and the clamping band.
Patent CA-2461536-A1 (CA)
Inventor: NATWORA JAMES PHILIP JR
IPC: B01D53/26
Filed: 2002-09-16
Abstract: A process for removing impurities such as oxygen, nitrogen, carbon monoxide, hydrogen, water (moisture), carbon dioxide, hydrogen chloride, methane and trace metals from crude hydrogen bromide and the apparatus for purifying such crude hydrogen bromide.
Patent CA-2465222-A1 (CA)
Title: Additive for oil-based drilling fluids
Inventor: MILLER JEFF
IPC: C09K8/36
Filed: 2002-10-29
Abstract: A method and product is disclosed which provides emulsion stability and filtration control to invert emulsion drilling fluids. The product comprises a blend of a carboxylic acid terminated polyamide and a mixture produced by the Diels-Alder reaction of dienophiles, preferably carboxylic acids, polycarboxylic acids, acid anhydrides, or combinations or mixes thereof, with a mixture of fatty acids and resin acids. The product is extremely effective, decreasing by about two-thirds the amount of emulsifier generally required to formulate an effective drilling fluid. The product also greatly reduces and in many cases eliminates the need for conventional fluid loss additives, and additionally provides electrical stability. Moreover, the product has a pour point as low as about 20 degrees Fahrenheit with minimal solvents, thereby eliminating the need to ship large amounts of inert material for use, and may be transported in a highly active state.
Patent CA-2466692-A1 (CA)
Title: Hot melt ink comprising a mixture of dyes
Inventor: HUINCK MARCUS PETRUS LEONARDUS
IPC: C09D11/02
Filed: 2004-05-07
Abstract: The invention relates to an ink composition which is solid at room temperature and liquid at a higher temperature, comprising a non-aqueous carrier composition and two compatible dyes, one of which is fluorescent and one non-fluorescent, wherein the said dyes are of the same type. In one embodiment, the dyes in the ink are both of the anthraquinone type.
Patent CA-2467272-A1 (CA)
Inventor: KNEIP ALAIN
IPC: C02F1/52
Filed: 2002-11-08
Abstract: The invention concerns a method for preparing an alkali metal ferrate, which comprises the following steps: (i) preparing a reaction mixture comprising at least an iron salt, at least an alkali or alkaline-earth metal hypochlorite and an alkali metal hydroxide; (ii) heating the mixture prepared at step (i) to a temperature ranging between 45 and 75 ·C, so as to form the alkali metal ferrate; (iii) recuperating the alkali metal ferrate formed at step (ii). The invention also concerns novel alkali metal ferrates.
Patent CA-2468743-A1 (CA)
Inventor: DEMERS M LINETTE
IPC: G01Q60/42
Filed: 2002-12-02
Abstract: L'invention concerne l'utilisation de la nanolithographie par ~criture directe destin~e ~ produire des motifs nanom~triques ancr~s d'acide nucl~ique sur diff~rents substrats, notamment des substrats ~lectroconducteurs et isolants. La modification d'un acide nucl~ique, notamment d'oligonucl~otides, avec des groupes r~actifs de type thiol permet de former des motifs au moyen de pointes de microscope sonde ~ balayage appropri~es dans des conditions appropri~es. Les groupes r~actifs permettent une chimisorption ou une liaison covalente sur la surface du substrat. Les structures d'acide nucl~ique obtenues qui pr~sentent une bonne stabilit~, peuvent Útre hybrid~es avec des acides nucl~iques compl~mentaires et sond~es en cons~quence, par exemple au moyen de nanoparticules fonctionnalis~es avec des acides nucl~iques. La mod~lisation peut Útre ma¹tris~e par une s~lection du traitement des pointes, de l'humidit~ relative, et de la structure d'acide nucl~ique.
Patent CA-2468848-A1 (CA)
Title: Fabric article treating method and apparatus
Inventor: GERLACH CHRISTIAN GERHARD FRIE
IPC: D06F58/10
Filed: 2002-12-19
Abstract: An in-home method for treating a fabric article in need of treatment with an electrically charged liquid and an in-home, self-contained, stand alone fabr ic article treating apparatus, such as a "cabinet" -type of apparatus, useful i n such method is provided.
Patent CA-2468950-A1 (CA)
Title: Anticorps de neutralisation du recepteur alpha 1 de l'il13
Inventor: MANABE TADASHI
IPC: C12N5/20
Filed: 2002-11-27
Abstract: L'invention concerne un nouvel anticorps anti-récepteur .alpha.1 de l'IL13 qui produit un effet inhibiteur sur la réponse cellulaire par IL13, et qui produit plus particulièrement un effet inhibiteur sur la réponse cellulaire par IL13 mais par sur la réponse cellulaire par IL4. L'invention concerne en outre la séquence d'acides aminés caractéristique située dans la région variable de celui-ci ; ainsi qu'un procédé de détection du récepteur .alpha.1 de l'IL13 dans un échantillon au moyen de cet anticorps.
Patent CA-2471428-A1 (CA)
Title: Compact hockey arena
Inventor: BANGERTER KIM
IPC: A63F7/22
Filed: 2002-12-20
Abstract: Systems and methods for providing a recreational game that promotes coordination, provides a form of exercise, and is an enjoyable pastime. A game box (10) includes a floor (12), side walls (14) and end walls (16), wherein each end wall includes a goal (18) formed therein. A center wall (22) extends up from the center of the floor (12) to divide the game box (10) into a plurality of playing areas, and includes one or more passages (24) formed therein to allow a puck (26) to pass from one side of the center wall (22) to the other. Each player utilizes a hockey stick (28) to manipulate a hockey puck (26). The game is started with a face-off procedure between the players, and once the puck (26) is in play the object is to send the puck (26) through the opponent's goal (28), which may first require sending the puck (26) through a hole in the center divider (22). After a goal is made, the face-off procedure is repeated and play resumes until one of the players reaches a predetermined number of goals.
Patent CA-2476403-A1 (CA)
Title: Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors
Inventor: CHAPPEY COLOMBE
IPC: C12Q1/68
Filed: 2003-02-14
Abstract: The present invention provides an approach for developing an algorithm for determining the effectiveness of anti-viral drugs based on a comprehensive analysis of paired phenotypic and genotypic data guided by phenotypic clinic al cut-offs. In one aspect, the algorithm allows one to provide a patient with effective treatment. It helps predict whether an infected individual will respond to treatment with an anti-viral compound, thereby allowing an effective treatment regimen to be designed without subjecting the patient to unnecessary side effects. Also, by avoiding the administration of ineffectiv e drugs, considerable time and money is saved.
Patent CA-2476591-A1 (CA)
Title: Azo dyes
Inventor: DREIER ROMEO
IPC: C07D213/85
Filed: 2003-03-13
Abstract: The present invention relates to an azo dye of formula (I) wherein R1 and R2 are each independently of the other -NH-(CH2CH2)-OH, -NH-CH2-CHOH-CH2-OH, -N H- (CH2CH2)-S-(CH2CH2)-OH, -NH-(CH2CH2)-NH-(CH2CH2)-OH, NH-CH2CH2-CON(CH2CH2OH) 2, R3 is -CN or -CONH2, R4 is methyl or trifluoromethyl, R5 is -CF3, -COOC2H5, R6 is hydrogen or chlorine and R7 is hydrogen, chlorine, bromine or -NO2, to a process for the preparation thereof and to the use thereof in a method of producing mass-coloured plastics or polymeric colour particles.
Patent CA-2477266-A1 (CA)
Inventor: YOKOYAMA HIROSHI
IPC: A47L9/16
Filed: 2003-03-18
Abstract: It comprises a dust separating section (60) disposed in an air suction duct extending from the connecting port (43) or suction port (52) of a cleaner ma in body (20) to the air suction opening (33A) in a motor fan (33) and adapted t o separate dust drawn into together with air through the connecting port (43) or suction port (52), and a dust collecting section for arresting the dust separated from the dust separating section (60). And the dust separating section (60) of this electric vacuum cleaner has a dust guide space into whi ch dust drawn in from the connecting port (43) or suction port (52) is flowed a t one end and that guides the inflow dust from the other end to the dust collecting section by inertial force, and an air guide duct is provided that communicates with somewhere between the ends of the dust guide space and tha t communicates with the air suction opening (33A) in the motor fan (33) withou t passing through the dust collecting section.
Patent CA-2477324-A1 (CA)
Title: Latch with shipping condition
Inventor: CETNAR ROMAN
IPC: E05B17/00
Filed: 2003-02-25
Abstract: A vehicle latch has a housing (18) with a detent (32) and a stop (34). A lever (12) is pivotally connected to the housing (18) and movable from an install position engaging the housing (18) to an active position pivoted away from the housing (18). A spring (16) extends from the lever (12) to the housing applying a biasing force to the lever (12) urging the lever to the install position. The spring (16) has a tail portion (20), a coil section (22) and an opposite end (24). The opposite end (24) engages the lever (12). The tail end (20) is moveable to engage either the stop (34) or detent (32). In the install position, the tail end (20) engages the detent (32) and also engages the lever (12). In this position, the spring (16) increases the biasing force holding the lever (12) in the install position. The tail end (20) is removable from the detent (32) to engage the stop when the lever (12) is first pivoted away from the install position. This disengages the tail end (20) from the lever (12) and also reduces the biasing force on the lever (12).
Patent CA-2478977-A1 (CA)
Inventor: LACELLE JEAN-GUY
IPC: F24H3/06
Filed: 2004-08-24
Abstract: The present invention is for a radiator heating system (electric) which uses a single radiator. The single radiator is connected to a 10-inch pipe through which glycol is heated by means of electricity. This single radiator is placed inside the central forced air furnace (non-electric) of a building. The fan of the central forced air furnace then circulates heat from the radiator throughout the building. The burner of the forced air furnace is not required to be used.
Patent CA-2479293-A1 (CA)
Title: Process for making engineered lignocellulosic-based panels
Inventor: SHANTZ ROGER M
IPC: D04H1/00
Filed: 2004-08-27
Abstract: A process for making engineered lignocellulosic-based panels with superior strength and dimensional stability. The process comprising adding to green lignocellulosic particles a low-nitrogen content, high molecular weight, phenol- formaldehyde resin before the green particles are dried. The resin is added in an amount from about 1 to 25 weight percent based on the dry weight of the green lignocellulosic particles. The resin has a nitrogen content of from about 0 to 3%, a viscosity of from about 20 to 2000 cps at 20°C, and a molar ratio of formaldehyde/phenol of from about 1.2 to 3Ø The green lignocellulosic particles treated with the resin are dried until the particles have a moisture content of from 1 to 8 %. A second resin is added to the dried particles and then the dried particles are consolidated under heat and pressure to form the engineered panel.
Patent CA-2482625-A1 (CA)
Title: Door lever construction with fragile handle
Inventor: EBERT DAVID A
IPC: E05B1/00
Filed: 2004-09-27
Abstract: A unique lever for being turned to actuate a door latch includes a shank mounted to the door. A handle, which is preferably crystal, is attached to an opposed end of the shank. A bolt extends through a bore in the handle and is secured to the shank, and at a remote end, to an end cap. The handle has a portion extending into a shallow pocket in both the shank and the end cap. The overall arrangement provides adequate support and a good force transmission surface from the handle to the shank such that the handle is unlikely to shatter.
Patent CA-2483927-A1 (CA)
Title: Treatment of diabetes and diabetic complications with nhe-1 inhibitors
Inventor: TRACEY WAYNE ROSS
IPC: A61K31/4184
Filed: 2003-04-22
Abstract: This invention relates to methods of treating or preventing type 2 diabetes, diabetic neuropathy, diabetic cardiomyopathy, cataracts, diabetic retinopath y, foot ulcers, diabetic microangiopathy, diabetic macroangiopathy, diabetic ischemia 5 reperfusion injury , diabetic cardiac ischemia reperfusion injury and/or insulin resistance syndrome (IRS) in mammals, particularly in humans, by administering a sodium-hydrogen exchanger type 1 (NHE-1) inhibitor or a pharmaceutical composition containing such an inhibitor. This invention also relates to combinations comprising NHE-1 inhibitors and a second pharmaceutical agent, said combinations being useful in treating type 2 diabetes, IRS, diabetic neuropathy, diabetic cardiomyopathy, cataracts, diabetic retinopathy, foot ulcers, diabetic ischemia reperfusion injury, diabetic cardiac ischemia reperfusion injury, diabetic microangiopathy and/or diabetic macroangiopathy.
Patent CA-2486100-A1 (CA)
Inventor: AGUILAR CORINNE
IPC: A23L29/00
Filed: 2003-04-11
Abstract: The present invention provides a simple and effective method for the preparation of emulsion food products comprising live desirable micro-organisms which have good longevity in the products. In particular, it provides a process for the preparation of an edible oil-in-water emulsion comprising live micro-organisms, by emulsifying an edible mixture comprising oil, water, live micro-organisms, emulsifier and a preservation system and wherein the process is carried out at a temperature of 35 ~C or less or without a heat treatment step. The emulsions are stored at a temperature of 8 ~C or less after preparation. Products produced according to the process are also provided.
Patent CA-2486909-A1 (CA)
Inventor: LIU JAMES H
IPC: A61K38/095
Filed: 2003-05-22
Abstract: Compositions and methods for vaginal, buccal or nasal transmucosal delivery of drugs and for cryoprotecting of cells and embryos. For cryoprotection, the composition consisting essentially consist of a no-ionizable glycol derivative. For transmucosal delivery, the compositions essentially consist of a non-ionizable glycol derivative in a combination with a pharmaceutically active agent. For transmucosal delivery, the non-ionizable glycol derivative may be further combined with a mucoadhesive agent and/or a penetration enhancer and/or lipophilic or hydrophilic carrier for adhesion to and transport through a mucosa. The compositions are particularly suitable for administration of drugs through a nasal, buccal and vaginal mucosa or for long-term preservation of cell or embryos.
Patent CA-2488361-A1 (CA)
Inventor: FERGUSON F MARK
IPC: A61J1/00
Filed: 2003-05-30
Abstract: L'invention concerne un appareil de protection d'aiguilles médicales comprenant une protection extensible pourvue de premier et second segments. Le second segment comporte une ouverture conçue pour enlever une aiguille médicale d'un dispositif à aiguille médicale, pendant la fixation de la protection extensible sur le dispositif à aiguille médicale. Ledit second segment forme une surface plane adjacente à une portion distale correspondante. La surface plane est élaborée pour rentrer en contact avec l'aiguille de manière à placer la protection en position étendue. Dans un autre mode de réalisation, l'appareil de protection d'aiguille médicale a une seringue possédant un raccord d'aiguille soutenant une aiguille. Le premier segment s'articule à partir d'un collier placé autour du raccord. Ledit collier comporte une paire de verrous. L'ouverture est conçue pour se déplacer autour de l'aiguille de manière à faciliter l'extension de la protection d'une position rétractée à une position étendue. Ce second segment comprend également un pivot proximal qui rentre en contact avec l'aiguille afin de faciliter l'extension de la protection. Ledit second segment a aussi une paire de loquets. Ces loquets peuvent rentrer en contact avec les verrous pour maintenir la protection en position rétractée. Le second segment a une portion de bec formant une surface plane conçue pour rentrer en contact avec l'aiguille de façon à faciliter la fixation de la protection en position étendue.
Patent CA-2493124-A1 (CA)
Title: Vaccin
Inventor: DENOEL PHILIPPE
IPC: A61K39/00
Filed: 2003-07-31
Abstract: L'invention concerne le domaine des compositions de vaccins à base de Neisseria, leur production et leur utilisation en médecine. L'invention concerne plus particulièrement des procédés de production de nouvelles souches de méningocoques mises au point par génie génétique plus appropriées pour produire des vaccins à base de vésicule de membrane extérieure (ou bleb) dérivés de Neisseria, en particulier de méningocoques. L'invention concerne également des procédés avantageux et des produits de vaccin basés sur l'utilisation d'une nouvelle sous-unité LOS ou des vaccins dérivés de vésicule de membrane extérieure (ou bleb) de méningocoque rendus plus sûrs et/ou plus efficaces lors de leur utilisation sur des sujets humains. L'invention concerne, en particulier, des combinaisons paticulières de régulations géniques négatives telles que PorA & OpA, PorA et OpC, OpA et OpC, et PorA, OpA, OpC. Dans un autre mode de réalisation ou en adjonction, on a découvert que lgtB?-¿ pouvait subir une mutation optimale afin d'utiliser L3 et/ou L2 LOS de manière plus sûre et plus efficace dans des compositions de vaccins dérivés de Neissera. L'invention concerne enfin des vaccins à base de bleb dérivés de lgtB?-¿ et des mutants de méningocoque à déficit en polysaccharide capsulaire ainsi que des procédés avantageux de production de préparations bleb dans lesquelles LOS est un antigène important.