baber/WOPTO huggingface dataset:
Patent EA-010573-B1 (EA)
Title: Hepatoprotective medicament and method for preparing thereof
Inventor: KHAVINSON VLADIMIR KHATSKELEVICH
IPC: A61P1/16
Filed: 2007-03-21
Abstract: A number of inventions relates to isolating a biologically active substance from animals liver and preparing a medicament for parenteral administration which can be used in medicine as a hepatoprotective preparation for parenteral administration and is a peptide complex, a low-molecular fraction content being from 70 to 90% with a molecular mass comprising the peptide components within 70 to 184 Da, peptide concentration being 2.5÷2.9 mg/ml for preparing thereof from calf liver aged less than 12 month or pigs by extracting acetic acid in the presence of zinc chloride. The proposed method for preparing a hepatoprotective medicament is characterized in that the calf liver aged less than 12 month or pigs is frozen at least -40°C, maintain at -20°C±22°C during at least 2 months, then crushed, add 3% solution of acetic acid in a volume ratio 1:5 at 20°C±5°C, extraction is performed at permanent agitation, after obtaining uniform suspension, 1% solution of zinc chloride is added in a volume ratio 50:1, cool at permanent agitation to 7°C±16°C, then mix for 1 hrs after 4 hrs of settling for 48 hrs, the extract is separated from balast substance by separating, acetone is added to the extract in a volume ratio 1:5, maintain at 3°C±5°C during 4 hrs, the formed homogenized sediment is repeatedly settled by acetone at least 2 times, then a sediment comprising the active substance, is washed through a nutsch filter by twofold volumes to 7°C±16°C of acetone to obtain light-grey sediment, rub through a metal sieve, dry, dissolve in distilled water at a room temperature and permanent agitation to polypeptide concentrate being 2.5÷2.9 mg/ml; centrifuging, filtering thereof with subsequent ultra-filtration purification at the apparatus with counter pressure not exceeding 1.0 kgs/cmusing materials with retention 15000 Da and adding glycocol in the ultrafiltrate to the final concentration 10÷20 mg/ml at pH=5.6÷6.6 mg/ml and subsequent sterile filtration, ampoulation and autoclaving for 8 minutes at 120°C and atmospheric pressure 1.1 kgs/cm.The invention provides the optimum technology of peptide complex isolation with a low-molecular fraction content being from 70 to 90% and with a molecular mass comprising the peptide components within 70 to 184 Da, and obtaining aqueous extract solution being 2.5÷2.9 mg/ml permitting not only to purify the obtained product from impurities but also the yield its production; and also characterized in that the obtained substance differs from prior art by molecular mass of peptide components comprising thereof and its non-toxicity and apyrogenity due to complete purification from impurities.
Patent EA-011329-B1 (EA)
Title: Process for the production of urea-comprising particles
Inventor: VAN DER WERF JAN WIEBE
IPC: C05G3/00
Filed: 2006-04-03
Abstract: Process for the production of urea-comprising particles, wherein the urea-comprising particles are produced in a pelletizer, comprising a feeding device, a belt and a device to remove the formed pellets from the belt, by feeding a urea- comprising liquid to the feeding device from which droplets of the urea-comprising liquid are dosed to the belt, whereon the urea-comprising droplets solidify and cool to a temperature of 55°C, whereafter the formed urea-comprising particles are removed from the belt.
Patent EA-014390-B1 (EA)
Title: Method for determining a minimum number of tests, preferably used for building materials and articles
Inventor: OSIPOV SERGEJ NIKOLAEVICH
IPC: E04G23/00
Filed: 2008-11-19
Abstract: The invention relates to the valuation of reliability, quality and other values preferably of building materials, articles, operations and systems as well as industrial and ecological environment for the purpose of ecological and industrial safety and sequencing of production methods and directed for reliability enhancement of normative properties of materials and articles, creation of an easy-to-use method of two-stage record of statistical variation of resistance of the materials and articles being tested in vitro. The essence of the method is characterised in that at least 4 samples are initially tested, then medians of a definable parameter and a coefficient of variation thereof are defined based on the results of the tests, and a minimal number of tests are defined based on the median of the definable parameter, potential decrease or increase thereof, the coefficient of variation and the necessary coefficient of statistical reliability.
Patent EA-013630-B1 (EA)
Title: Vane machine with stationary and rotating cylinder parts
Inventor: BOSKOVIC NEBOJSA
IPC: F01C1/348
Filed: 2006-03-06
Abstract: Vane machine with cylinder stationary and rotating parts is intended for use as a driving or a working machine, utilising compressible or non-compressible media as the working fluid. The vane-machine basic embodiment comprises: cylinder stationary part (A), cylinder rotating parts (B)1 rotor (C), covers (D), and vanes with grooves (F). The cylinder stationary part has the shroud (1) in which rotates the rotor with the vanes. In the shroud there are radial rectangular openings (5 and 6), letting the media in and out, which openings may be of other shapes as well. The inner ring (8) of roller or sliding bearing, rotate driven by the vanes. The rotor is positioned eccentrically relative to the shroud axes. At the rotor there are firmly fitted lateral plates (14) that rotate jointly with the rotor. The vane-machine working chamber is delimited with the shroud, the inner rings, the vanes and the plates. The described machine is better charged and discharged with the working media, its volumetric efficiency is improved, and its sealing is more efficient. Losses resulting from friction between surfaces in contact are decreased whereby the mechanical efficiency of the machine is enhanced.
Patent EA-016365-B1 (EA)
Title: Radio communication system and mobile station device
Inventor: YAMADA SHOHEI
IPC: H04W74/08
Filed: 2008-08-07
Abstract: A mobile station device transmits a random access preamble to a base station device and performs uplink timing adjustment according to synchronization timing shift information contained in a random access response transmitted from the base station device in response to the received random access preamble. In the case of an uplink synchronization state, the mobile station device does not perform the uplink timing adjustment based on the synchronization timing shift information contained in the random access response as a response to the random access preamble of a preamble ID selected at random by the mobile station device.
Patent EA-014797-B1 (EA)
Title: Device for filling containers of collapsible type
Inventor: GUSTAFFSON PER
IPC: B65B3/17
Filed: 2007-10-25
Abstract: The invention relates to a device for filling a container of a collapsible type with a product in the form of powder or liquid, said container having a compartment which is defined by flexible walls and whose volume is dependent on the relative position of the walls and which communicates with the surroundings through a filling duct of the container, comprising a valve housing with a filling tube, which is insertable into said filling duct of the container to supply a product to the compartment of the container through a product path which is defined by the valve housing and its filling tube, a piston element arranged in the product path and comprising a valve body and, arranged downstream thereof, an end element, the piston element being movable between a first position, in which the valve body abuts against a valve seat of the valve housing to block the product path and the end element is arranged in or adjacent to an outlet portion of the filling tube to counteract dripping, and a second position, in which the valve body is displaced from the valve seat to open the product path and the end element takes a position, in which it defines, together with the outlet portion, a filling passage, and a squeezing means, which is arranged to grip the filling tube and the filling duct when said filling tube is inserted in said filling duct to establish a seal between the filling tube and the filling duct, said filling tube being made of a rigid material.
Patent EA-018472-B1 (EA)
Title: Erythropoietin-containing particles for treatment and prophylaxis of neurologic and hematologic diseases and disorders
Inventor: BALABANYAN VADIM YURIEVICH
IPC: A61K9/127
Filed: 2010-09-15
Abstract: Particles are proposed containing 20-80 wt% of erythropoietin 1-1000 mkm in size representing pharmaceutically acceptable, biocompatible and biodegradable (co)polymeric matrices and lyposomes, in which recombinant human or modified alpha erythropoietin or an analog thereof is physically encapsulated or sorbed on the surface thereof. Said particles can be used for preparing medicaments for the treatment and/or prophylaxis neurologic and hematologic diseases and disorders.
Patent EA-019038-B1 (EA)
Title: Sulfonate salts of 2-amino-3-carbethoxylamino-6-(4-fluorobenzylamino)pyridine
Inventor: HOOCK CHRISTOPH
IPC: A61K31/44
Filed: 2009-06-09
Abstract: Flupirtine acid addition salts having the following formula (2), wherein R represents a substituted or unsubstituted C-C-alkyl or a substituted or unsubstituted C-C-aryl group, have been prepared.
Patent EA-019007-B1 (EA)
Title: Fungicidal composition
Inventor: TOBLER HANS
IPC: A01N29/00
Filed: 2008-04-23
Abstract: A composition suitable for control of diseases caused by phytopathogens comprising: (A) a compound of Formula (I) wherein Ris difluoromethyl or trifluoromethyl and X is chloro, fluoro or bromo; and (B) is a fludioxonil compound with a fungicidal activity; and a method of controlling diseases on useful plants, especially rust diseases on soybean plants.
Patent EA-027250-B1 (EA)
Title: Cooling and processing materials
Inventor: MEDOFF MARSHALL
IPC: C12P7/10
Filed: 2009-07-15
Abstract: Systems and methods for cooling and processing materials are disclosed.
Patent EA-020058-B1 (EA)
Title: Solid dosage form having neuroprotective, antiamnesic, antioxidant, antihypoxic and anti-ischemic activity (variants)
Inventor: CHELYAEVA ANASTASIYA GENNADIEVNA
IPC: A61K9/14
Filed: 2012-03-14
Abstract: The invention relates to the pharmaceutical industry and the field of medicine and can be used in the creation and administration of solid dosage forms having neuroprotective, antiamnesic, antioxidant, antihypoxic and anti-ischemic activity. The aim of the present invention is to create a solid dosage form having neuroprotective, antiamnesic, antioxidant, antihypoxic and antiischemic activity, by means of using 2-ethyl-6-methyl-3-hydroxypyridine succinate, mineral substances,C isotopes andN isotopes. The technical results of the invention are a more rapid onset of therapeutic effect, an enhanced therapeutic effect with no increase in the concentration of the 2-ethyl-6-methyl-3-hydroxypyridine succinate preparation, and improved stability for the duration of the shelf life.
Patent EA-023625-B1 (EA)
Title: Traditional chinese drug comprising danshen extracts and sanqi extracts and use thereof
Inventor: HAN JINGYAN
IPC: A61P9/10
Filed: 2010-12-17
Abstract: The present invention discloses a traditional chinese drug consisting of Danshen extracts and Sanqi extracts, the pharmaceutical composition comprising the above traditional chinese drug as active component and the use thereof. The traditional chinese drug consists of Danshen extracts and Sanqi extracts by weight ratio of (1-4):(1). The invention further discloses the effect of the traditional chinese drug and the pharmaceutical composition comprising the above traditional chinese drug as active component for treating cardiac microcirculation disturbance and myocardial damage induced by ischemia reperfusion.
Patent EA-021523-B1 (EA)
Title: Mobile complex for arranging radioelectronic facilities
Inventor: JUKHNEVICH DENIS VLADIMIROVICH
IPC: H05K7/00
Filed: 2012-06-08
Abstract: The invention relates to communication and telecommunication facilities, radioelectronic and opticoelectronic monitoring and is provided for arranging antenna and opticoelectronic systems, radioelectronic equipment and use in mobile, quickly developable communication complexes. A mobile complex for arranging radioelectronic facilities comprises chasses with a frame 1, whereto an apparatus module 2, a power supply source 3, expandable outriggers 4 are fixed, a mast 5 with a drive 6 for its lifting/lowering fixed to the frame 1 using a support post 7, on the upper end of which a horizontal frame 8 for tension ties is rigidly fixed, the frame angles are equally-spaced from each other in the frame 8 plane, equally-spaced from axis of the support post 7 and connected thereto by radial beams 9. The ties 10 are connected by one end to a corresponding drive 11 having a regulator of tension strength and fixed on the frame 1 behind the support post 7 at its base, and by the other end through the corresponding bypass blocks 12 at a rear side 13, at the radial beams 9 and at angles of the frame 8, to the upper flange 14 of the mast 5. The mobile complex is installed for developing on a selected site followed by displaying and horizontilizing by means of the expandable outriggers 4, and simultaneously with lifting the telescopic mast 5 to a vertical position and tensioning the ties 10 through the corresponding bypass blocks 12 positioned on the rear side 13 of the frame 8, at the radial beams 9 and at angles of the frame 8. After completing the complex horizontilizing and putting the telescopic mast 5 to a vertical position the telescopic mast 5 is lifted to a maximum height. The mobile complex is developed for not more than 10 minutes, wherein improving its operation characteristics.
Patent EA-028447-B1 (EA)
Title: Hydraulic actuation of a downhole tool assembly
Inventor: WU JIAN
IPC: E21B10/30
Filed: 2011-05-20
Abstract: A downhole tool assembly is configured for repeated and selective hydraulic actuation and deactuation. A piston assembly is configured to reciprocate axially in a downhole tool body. The piston assembly reciprocates between a first axial position and second and third axial positions that axially oppose the first position. The downhole tool is actuated when the piston assembly is in the third axial position and deactuated when the piston assembly is in either of the first or second axial positions. A spring member biases the piston assembly towards the first axial position while drilling fluid pressure in the tool body urges the piston assembly towards the second and third axial positions. Downhole tool actuation and deactuation may be controlled from the surface, for example, via cycling the drilling fluid flow rate.
Patent EA-022771-B1 (EA)
Title: Process and apparatus for producing packets
Inventor: FORD THOMAS DAVID REID
IPC: B65B29/02
Filed: 2011-06-29
Abstract: A process for sequentially forming a plurality of enclosed tetrahedral containers (32) comprising a product, the process involving passing a continuous web (10), comprising a strip of container material having two opposing edges (4, 6), to a folding station (12), whereupon each open container with one face missing is formed by folding the web, to bring into contact two contiguous edge portions (9a, 9b) from only one edge of the web, then sealing the two edges together to form a portion of the web into an open container with one face missing, depositing the product onto the web so that it is held within the open container, and then sealing the open containers to form the enclosed tetrahedral containers.
Patent EA-028081-B1 (EA)
Title: Composition for treating prostate cancer, method for treating an individual having prostate cancer and method for inducing an immunotherapeutic response in the same
Inventor: HEAD JONATHAN F
IPC: A61K38/20
Filed: 2012-01-09
Abstract: The present invention relates to medicine and describes pharmaceutical compositions useful as vaccines for treating prostate cancer containing purified surface or excreted proteins comprising (i) about 50 μg prostate specific antigen (PSA), about 2 μg carcino-embryonic antigen (CEA) and about 1000 IU CA 125 antigen, (ii) about 20,000 units IL-2, (iii) about 16.7 μg granulocyte macrophage colony stimulating factor (GM-CSF), and (iv) a pharmaceutically acceptable carrier per dose 500 μl by volume. Such compositions can be used in methods for treating individuals having prostate cancer, and for inducing an immunotherapeutic response in the same.
Patent EA-027764-B1 (EA)
Title: Fuel cells
Inventor: SUTHERLAND HUGH LIAM
IPC: H01M8/08
Filed: 2012-01-18
Abstract: A liquid electrolyte fuel cell comprises means to define an electrolyte chamber (208), and two electrodes (10), one on either side of the electrolyte chamber (208), each electrode comprising a sheet (11) of metal through which are defined a multiplicity of through-holes (14), and a gas-permeable layer (16) of fibrous and/or particulate electrically-conductive material which is bonded to and in electrical contact with the sheet of metal (11), and which comprises catalytic material (18). The electrode (10) may be arranged such that the gas-permeable layer (16) faces the electrolyte chamber (208).
Patent EA-032513-B1 (EA)
Title: Low fucose cell lines and uses thereof
Inventor: HELMAN DANIEL
IPC: C12N15/01
Filed: 2012-03-05
Abstract: The present invention relates to a method of producing Chinese hamster ovary CHO-S cells having a zero fucose level useful as host cells for expressing a recombinant protein, the method comprising treating a population of CHO-S cells with methotrexate (MTX) in a concentration of 100-200 nM, which causes mutation in GDP-mannose 4,6-dehydratase (GMD) gene, provision of a contact of the produced population of CHO-S cells containing mutant cells with non-toxic lectin during not longer than 60 min, which allows binding of lectin with a fucose moiety on the cell membrane of said cells, the amount of time not allowing killing of the cells; isolation of a subpopulation of cells that are bound with lectin, thereby selecting cells useful as host cells for expressing recombinant proteins, the selected cells having zero fucose content in the absence of external fucose, wherein the mutated GMD lacks amino acids encoded by exons 3 and 4 or lacks amino acids encoded by exons 8 and 9; the invention discloses also various embodiments of the method. Further, the invention is related to an isolated CHO-S cell produced by such method, to a cell line containing said isolated cell, to a cell culture containing said isolated cell and a cultural medium free of animal admixtures, and to a method for producing a recombinant protein comprising transfection of said isolated cell with CHO-S polynucleotide encoding the recombinant protein, cultivation of the transfected CHO-S cell under conditions suitable for expression of the recombinant protein, and isolation of said protein.
Patent EA-022624-B1 (EA)
Title: Hepatitis c virus inhibitors
Inventor: HIEBERT SHELDON
IPC: C07K5/12
Filed: 2012-05-01
Abstract: Hepatitis C virus inhibitors having the following general formula (I) are disclosed:Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
Patent EA-030740-B1 (EA)
Title: Process for production of hydrogen rich gas mixtures
Inventor: IAQUANIELLO GAETANO
IPC: C01B3/56
Filed: 2012-07-26
Abstract: The present invention relates to a process for producing a hydrogen containing gas mixture comprising the following steps: (i) providing a preheated mixture comprising a fossil fuel, preferably methane, and steam, (ii) conducting an adiabatic reaction between the fossil fuel and the steam, in the presence of a catalyst, wherein a first reaction product mixture is formed comprising methane, hydrogen and carbon dioxide, and (iii) conducting an oxygen-assisted reforming reaction in the presence of a catalyst between said first reaction product mixture and an oxygen comprising stream, wherein the oxygen comprising stream comprises at least 40 vol% oxygen, forming a second reaction product mixture comprising hydrogen and carbon monoxide. The invention also relates to a system suitable for hydrogen production from a hydrocarbon feed according to the present invention.
Patent EA-024260-B1 (EA)
Title: Process for the production of n-substituted 2-(acetylamino)-n'-benzyl-3-methoxypropanamides
Inventor: WEHLAN HERMUT
IPC: C07C237/22
Filed: 2012-11-14
Abstract: A process for the production of N-substituted 2-(acetylamino)-N'-benzyl-3-methoxypropanamides and subsequent treatment with acids are described. This process can be used for the production of (R)-Lacosamide.
Patent EA-033783-B1 (EA)
Title: Metabolically optimized cell culture
Inventor: LAWRENCE SHAWN
IPC: C12N5/02
Filed: 2014-10-10
Abstract: An improved method for large scale production of proteins and/or polypeptides in cell culture is provided. In accordance with the present invention, the method provides for culturing cells that have metabolically shifted. The use of such a method or system allows high levels of protein or polypeptide production and reduces accumulation of unwanted metabolic waste such as lactate. Proteins and polypeptides expressed in accordance with the present invention may be advantageously used in the preparation of pharmaceutical, immunogenic, or other commercial biologic compositions, such as antibodies.
Patent EA-031295-B1 (EA)
Title: Process for converting a biomass into at least one biochar
Inventor: VIESLET JEAN-PAUL
IPC: C10L9/08
Filed: 2015-02-11
Abstract: The invention relates to a process for converting a biomass into at least one biochar, comprising the following steps: (a) a ground and dried biomass is provided, said biomass containing at least 30% of a lignocellulosic biomass, by mass relative to the dry mass of the ground and dried biomass; (b) this biomass is gradually heated at a temperature above 140°C and below 350°C, in an oxygen-free gas stream, under a pressure of between 1 and 40 bar; (c) the reaction is left to take place by maintaining the temperature within the range of 300-700°C and the pressure within the range of 1-40 bar; (d) the biomass resulting from (c) is cooled to a temperature of at most 100°C in an oxygen-free gas stream; and (e) the biochar is recovered. The invention also relates to the biochar thus obtained.
Patent EA-032762-B1 (EA)
Title: Solid formulations containing omega-3 and resveratrol
Inventor: GIANNINI GIUSEPPE
IPC: A61K9/20
Filed: 2015-03-26
Abstract: The present application relates to the invention of a solid composition comprising omega-3 polyunsaturated fatty acids (n-3 PUFA), or their alkyl esters, and resveratrol, adsorbed on an inert substrate, wherein the recovery of omega-3 is at least 96% after 6 months at 25°C. The composition according to the present invention can be formulated as food supplement or medicament for preventing or treating cardiovascular diseases due to lipid metabolism disorders and increased platelets aggregation; damages due to free radicals selected from the group consisting of atherosclerosis, cancer, inflammatory joint diseases, asthma, diabetes, senile dementia and degenerative eye disease; and/or viral diseases.
Patent ES-2178577-B1 (ES)
Title: Sensor de recipiente en una placa de cocina, con un circuito de medicion a baja frecuencia.
Inventor: ARBE AURRE ISMAEL
IPC: F24C7/08
Filed: 2000-11-24
Granted: 2003-09-16
Abstract: "Sensor de recipiente en una placa de cocina, con un circuito de medición a baja frecuencia". El circuito (1) sensor detecta en una placa eléctrica de cocina la presencia de un recipiente (2) en cada foco (F1-F4) de caldeo, y comprende un microcontrolador (4) y un generador (6,7) que suministran una corriente (Ig) de alta frecuencia a una respectiva espira sensora (E1-E4) y un campo magnético, y dos señales (Vr0,Vr1) de referencia máxima y mínima para todos los focos (F1-F4) obtenidas en la condición de temperatura de trabajo, y un circuito (9-13) de medición y evaluación del voltaje (Vs) producido en cada espira sensora, y un circuito (11,11'') para la demodulación en baja frecuencia dichas señales (Vs,Vr0,Vr1), y su amplificación diferencial (Vm,Vrr).