baber/WOPTO huggingface dataset:
Patent BR-9909382-A (BR)
Title: Anticorpo humanizado contra o fator tissular humano (tf) e processo de produção de anticorpo humanizado
Inventor: SATO KOH
IPC: C12P21/08
Filed: 1999-04-02
Abstract: Patente de Invenção: <B>"ANTICORPO HUMANIZADO CONTRA O FATOR TISSULAR HUMANO (TF) E PROCESSO DE PRODUçãO DO ANTICORPO HUMANIZADO"<D>. Um anticorpo humanizado contra o fator tissular (TF) compreendendo: A: uma cadeia H humanizada compreendendo (1) uma região V de cadeia H compreendendo as CDRs de cadeia H de um anticorpo monoclonal de camundongo contra o TF e as FRs de cadeia H de um anticorpo humano; e (2) a região C de cadeia H de um anticorpo humano; e B: uma cadeia L humanizada compreendendo (1) uma região V de cadeia L compreendendo as CDRs de cadeia L de um anticorpo monoclonal de camundongo contra o TF e as FRs de cadeia L de um anticorpo humano; e (2) a região C de cadeia L de um anticorpo humano. Após gerar uma região V humanizada mediante a enxertia dos CDRs de um anticorpo monoclonal de camundongo em um anticorpo humano, um anticorpo humanizado tendo uma atividade mais elevada é pesquisado mediante a substituição da FR da região acima com a FR correspondente do anticorpo humano tendo uma homologia elevada.
Patent BR-9911600-A (BR)
Title: Recursos e métodos para monitoração de terapia antiretroviral inibidora de transcriptase reversa de não nucleosìdeo
Inventor: WHITCOMB JEANETTE
IPC: C12Q1/68
Filed: 1999-05-26
Abstract: Patente de Invenção: <B>"RECURSOS E MéTODOS PARA MONITORAçãO DE TERAPIA ANTIRETROVIRAL INIBIDORA DE TRANSCRIPTASE REVERSA DE NãO NUCLEOSìDEO"<D>. Esta invenção refere-se a testes de resistência e suscetibilidade à droga antiviral a serem empregados em identificação de regimes de droga eficaz para o tratamento de infecção por vírus de imunodeficiência humana (HIV) e síndrome da imudeficiência adquirida (AIDS) e ainda refere-se aos recursos e métodos de monitoração da progressão clínica de infecção HIV e sua resposta à terapia antiretroviral, particularmente terapia inibidora de transcriptase reversa de não nucleosídeo emregando-se ensaios de suscetibilidade fenotípica ou ensaios genotípicos.
Patent BR-9912025-A (BR)
Title: Composição de catalisador e métodos para sua preparação e uso em um processo de polimerização
Inventor: AGAPIOU AGAPIOS KYRIACOS
IPC: C08F4/44
Filed: 1999-06-23
Abstract: Patente de Invenção: <B>"COMPOSIçãO DE CATALISADOR E MéTODOS PARA SUA PREPARAçãO E USO EM UM PROCESSO DE POLIMERIZAçãO"<D>. A presente invenção refere-se a uma composição de catalisador e a um método para fabricação de uma composição de catalisador compreendendo um catalisador de polimerização e um sal de carboxilato de metal. A invenção também refere-se ao uso da composição de catalisador na polimerização de olefina(s). Em particular, o sistema de catalisador de polimerização é suportado sobre um veículo. Mais particularmente, o catalisador de polimerização compreende um sistema de catalisador do tipo metaloceno com um ligando de alto teor de massa.
Patent BR-9912466-A (BR)
Title: Utilização de sulfamatos de estrogênio biogênicos na terapia de reposição hormonal
Inventor: ELGER WALTER
IPC: A61K31/565
Filed: 1999-05-13
Abstract: Patente de Invenção: <B>UTILIZAçãO DE SULFAMATOS DE ESTROGêNIO BIOGêNICOS NA TERAPIA DE REPOSIçãO HORMONAL''<D>. Descreve-se a utilização de sulfamatos de estrogênio biogênicos em aplicação oral e descontínua na terapia de reposição hormonal (HRT). A administração descontínua faz-se em intervalos de 2 a 40 dias. Também se provê a aplicação suplementar de gestágenos, de preferência continuamente na forma de um implante ou na forma de um sistema de liberação intra-uterina (DIU). Enquanto sulfamatos de estrogênio biogênicos, utilizam-se sulfamato de estrona, sulfamato de estradiol, sulfamato de estriol, ou um N-acilsulfamato de estrona, estradiol ou estriol com até 7 átomos de carbono na cadeia da acila, ou uma combinação de dois ou mais dos ditos ingredientes ativos.
Patent BR-9912967-A (BR)
Inventor: CONNER WILLIAM A
IPC: G02C5/00
Filed: 1999-07-06
Abstract: A case for glasses in the shape of a writing instrument having a hollow barrel portion for receiving a pair of small glasses. The case can take a plurality of different cross-sectional configurations. The writing instrument can be a pen or pencil at one end of the hollow barrel with an opening with a removable cover at the opposite end. The glasses for use therewith can be small conventional glasses or specially designed glasses that can have both telescopic frames and telescopic temples.
Patent BR-9913268-A (BR)
Inventor: BIRKE PETER
IPC: H01M10/40
Filed: 1999-08-27
Abstract: The invention relates to a paste-like mass that can be used in electrochemical elements comprising a matrix comprising at least one organic polymer, precursors thereof, or prepolymers thereof, and an electrochemically activatable inorganic material that is not soluble in the matrix and that is in the form of a solid substance, whereby either (a) the mass comprises at least 60 vol. % (B) and, if (B) is an electrode material, (B) is worked into the matrix (A) without the assistance of a solvent or swelling agent or the matrix (A) also contains a plasticizer for the organic polymer, and the plasticizer is subsequently removed using a suitable solvent, (C) and/or (c) the mixture also contains a solid ion electron and/or mixed conductor that is different from (B) and that is present at least at the grain limits between (A) and (B) as a thin layer.
Patent BR-9913530-A (BR)
Inventor: ENGL BERNHARD
IPC: C22C38/00
Filed: 1999-09-06
Abstract: The present invention concerns a method for the production of cold-rolled bands or sheets from low-alloy steel with a maximum of 0.2% C, Al, Ti, V, Nb respectively and a maximum of 1% Si and Mn respectively, in addition to a portion of boron required for N binding (>0,78xN), the remainder being constituted by iron and unavoidable impurities, wherein said steel is cast after melting to slabs, thin slabs or a band, which are hot-rolled at a starting temperature above 1100° C. and at a final temperature below Ar3 and wherein the hot band is then drawn and cold-rolled at a temperature below 650° C., whereupon the cold band is annealed independently of the degree of cold-rolling at a low temperature that could possibly vary depending on the composition of the steel and ranging from 520 to 780° C. during a period of time that is sufficiently long to allow for complete recrystallization. The method disclosed makes it possible to simplify manufacturing and to lower production costs associated with the manufacture of a completely recrystallized cold-rolled band or sheet.
Patent BR-9914363-A (BR)
Title: Método de processamento de feijão de soja mediante o uso de uma enzima, feijão de soja processado obtido pelo mesmo método, e alimento contendo o feijão de soja processado
Inventor: AKAZAWA TORU
IPC: A23L23/00
Filed: 1999-08-06
Abstract: Patente de Invenção:<B>MéTODO DE PROCESSAMENTO DE FEIJãO DE SOJA MEDIANTE O USO DE UMA ENZIMA, FEIJãO DE SOJA PROCESSADO OBTIDO PELO MESMO MéTODO, E ALIMENTO CONTENDO O FEIJãO DE SOJA PROCESSADO''<D>. é fornecido um método de processamento de feijão de soja mediante o uso de uma enzima. Depois o feijão de soja é impregnado em água, ele é cozido no vapor. O feijão de soja cozido no vapor é esfriado, e então água e pectinase produzida por microorganismos do gênero Bacillus são adicionadas ao feijão de soja para preparar uma primeira mistura. A primeira mistura é sustentada por um período de tempo predeterminado enquanto é agitada para executar um tratamento de enzima, de modo que a pasta fluida é obtida, em que as células únicas do feijão de soja são dispersas. Após o tratamento de enzima, a pectinase é inativada. Logo depois, a pasta fluida é misturada com um pó obtido pelo processamento de um grão de leguminosa diferente do feijão de soja para se obter uma segunda mistura. A segunda mistura é seca  pela operação de secagem instantânea ou secagem por pulverização para se obter um pó de feijão de soja processado. Por omitir as etapas executadas após a etapa de inativação da pectinase, é possível se obter um líquido de feijão de soja processado, em qua as células únicas do  feijão de soja são dispersas.
Patent BR-9914639-A (BR)
Inventor: BOUQUET ERIC
IPC: A45D20/12
Filed: 1999-10-29
Abstract: The invention concerns a hair brushing accessory designed to be fixed to the air blowing nozzle end of a hairstyling or hair drying appliance, comprising a hollow body (2) bearing means (6, 7) for gripping a hair lock. The invention is characterised in that said gripping means comprise at least a squeezing surface (6'') urged, by the action of elastic means, to press against an opposite matching support surface (7'') to squeeze and brush a hair lock, the squeezing surface and/or the support surface having a bevel (6', 7') for inserting the hair lock and arranged in the air flow, substantially parallel thereto.
Patent BR-9915967-A (BR)
Title: Derivados de propanolamina substituìdos por arila, proceso para sua preparação, medicamentos contendo estes compostos e seu uso
Inventor: FRICK WENDELIN
IPC: A61K31/7028
Filed: 1999-09-18
Abstract: Patente de Invenção: <B>"DERIVADOS DE PROPANOLAMINA SUBSTITUìDOS POR ARILA, PROCESSO PARA SUA PREPARAçãO, MEDICAMENTOS CONTENDO ESTES COMPOSTOS E SEU USO"<D>. A invenção refere-se a derivados de propanolamina substituídos e sais farmaceuticamente compatíveis e derivados fisiológicos funcionais. Descrevem-se compostos da fórmula (I) na qual os radicais têm os significados dados, bem como seus sais fisiologicamente compatíveis, derivados fisiológicos funcionais e processo para sua preparação. Os compostos são apropriados por exemplo como agentes hipolipidêmicos.
Patent BR-9916011-A (BR)
Inventor: NOGUERAS MIGUEL CLE
IPC: B22C11/00
Filed: 1999-10-08
Abstract: Based on a tubular chamber in the body of which two movable walls can be operated, one associated with the compacting and expulsion piston for the cake and the other associated with a hinged and displaceable arm, for opening the chamber, its characteristics centre on the fact that the side walls thereof are also movable, being each comprising a plate (11) in association with a respective plate-holder (12) provided with guides (13) in order to sliding on a fixed support (14) through the action of a respective hydraulic cylinder (15), in such a manner that the effective width of the chamber can be adapted to different cake sizes, in order to minimise the consumption of sand. Additionally the classic movable arms, those associated with the hydraulic cylinder for compacting and expulsion and the hinged arm, are materialised in respective pattern plates each mounted on individual plate-holder frames, which constitute replaceable assemblies, of different widths, adjustable in any case to a fixed faceplate, of width equal to or less than the minimum width foreseen for the chamber and joined in one case to the hydraulic cylinder and in the other to the hinged arm. <IMAGE>
Patent BR-9916195-A (BR)
Title: Dispositivo para transmissão de um movimento
Inventor: MALNER BERND
IPC: H01H3/46
Filed: 1999-12-14
Abstract: Patente de Invenção: <B>"DISPOSITIVO PARA TRANSMISSãO DE UM MOVIMENTO"<D>. A presente invenção refere-se a um dispositivo para transmissão de um movimento, que, na dependência de um primeiro movimento de translação de um primeiro elemento de acoplamento (1), ao qual é acoplável um primeiro componente (2), produz um movimento de translação de um segundo elemento de acoplamento (3), ao qual é acoplável um segundo componente (4), está previsto de acordo com a invenção que o primeiro e o segundo elemento de acoplamento (1, 3) estejam interligados de modo móvel por meio de um primeiro elemento (7) rígido e que o primeiro elemento de acoplamento esteja unido com uma primeira alavanca (8) disposta de modo fixo e o segundo elemento de acoplamento (3), com uma segunda alavanca (10) disposta de modo fixo. Pela disposição, é obtido que na transmissão de movimento, o movimento dos segundo componente (4) pode ser primeiramente retardado e, depois, novamente acelerado de modo correspondente ou vice-versa.
Patent CH-500190-A (CH)
Title: 1-benzoyl-2-methyl-3-indolylacetic acid derivs
Inventor: JOHN MARTIN CHEMERDA
IPC: C07D209/28
Filed: 1967-08-16
Abstract: preparation of 3-indolylacetic acid derivatives of formula:- (I) where R = methoxy or dimethylamino The synthesis is considerably shorter than the method already described for the preparation of (I), U.S.Patent 3,161,654. 5.9 g. concentrated sulphuric acid is cooled to 5 deg.C and to it is slowly added with stirring 0.92 g. anhydrous formic acid while cooling to maintain the temperature between 0 and 5 deg.C. To this mixture 1.65 g. of 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylmethanol is added in portions at 0 deg.C in a nitrogen atmosphere. After standing 6 hr. at this temperature, the mixture is poured into 50 ml. ice cold water and the precipitate is filtered off, washed with water and recrystallised from t-butanol, to give the 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid.
Patent CH-499322-A (CH)
Title: Coloured resins made by condensing alcohols and dyes with maleic anhyd - ride copolymers
Inventor: GREGOIRE KALOPISSIS
IPC: A61K8/81
Filed: 1966-09-02
Abstract: Coloured resin (V) resulting from simultaneous condn. of 80-95% alcohol(s) and 20-5% hydroxylated or amino dye(s) with a polymer obtd. by copolymerisation of equimol. amts. of maleic anhydride and an unsatd. monomer, e.g. vinyl alkyl ether, ethylene, vinyl acetate, alkyl acrylate, alkyl methacrylate or acrylonitrile.
Patent CH-511821-A (CH)
Title: Dehydroepiandrosterone esters
Inventor: UFER JOACHIM DR
IPC: A61K/
Filed: 1968-09-09
Abstract: Esters of 3beta-hydroxy-5-androsten-17-one with carboxylic acids (C3-C14), especially the oenanthate. - Treatment of menopausal symptoms, osteoporosis, cardiac and circulatory troubles, depressive states and senile deafness; no androgenic side effects, CNS inhibitory, oestrogenic or anti-oestrogenic effect. Preferably combined with an oestrogen. For oral admin. - Conventional methods using dehydroepiandrosterone with the acid anhydrides or with the acid chlorides and pyridine. - Preferably 0.5 - 10 mg. of oestrogen, especially 4 mg. of oestradiol valerate with 50 - 500 mg. of dehydroepiandrosterone ester especially 100 - 300 g. of the oenanthate.
Patent CH-513889-A (CH)
Title: Improved method for: and salts of (I) where R1, R2, R3 and R4 = H, alkyl, alkenyl, cycloalkyl, aralkyl, and/or aryl, or and/or = an opt. substd.
Inventor: HIDEO TANI
IPC: C07D403/06
Filed: 1968-11-15
Abstract: Improved method for: and salts of (I) where R1, R2, R3 and R4 = H, alkyl, alkenyl, cycloalkyl, aralkyl, and/or aryl, or and/or = an opt. substd. satd. heterocyclic residue, opt. cont. another heteroatom R5 = opt. substd. aryl or pyridyl. Hypotensives and diuretics (q.v. NE.68, 10196) LD50 for (I) (R1 = R2 = Me, R5 = Ph, NR3R4 = morpholino), (i.v. mouse) = 125-500 mg./kg. Biguanide. HCl (3.48 g.) and ethyl phenylmorpholino acetate (5. 1 g.) were refluxed 6 hr. with Na(0.92 g.) in MeOH (15 ml.), evapd. in vac., the residue mixed with H2O, filtered, and recryst. from EtOH, giving (I) (R1 = R2 = H, R5 = Ph, NR3R4 = morpholino), m.p. 236 deg.
Patent CH-516660-A (CH)
Title: Humidity control - in fibre flock feed channel with steam jet under sensor control to correct humidity level
Inventor: WILDBOLZ RUDOLF DIPL ING
IPC: D01G99/00
Filed: 1968-11-20
Abstract: The supply channel, to carry fibre flock material in an air stream to feed a carding machine, is fitted with a sensor linked through a control circuit to a steam jet. The purpose is to monitor the humidity of the material and to dose it with water-rich steam vapour to control the humidity level in the material to prevent blockages through electrostatic action if the material is too dry, or from balling and sticking if too wet.
Patent CH-540296-A (CH)
Title: 6 substd purine ribonucleoside 3,5 cyclic phosphates
Inventor: RER NAT WEIMANN GUENTER DR
IPC: C07H19/20
Filed: 1969-09-08
Abstract: 6-Substd purineribonucleoside-3',5'-cyclic phosphates. N3A. are new compds. of formula (I): (where X = hal, an ether residue or NR'R2, where R' and R2 = (1-18C) alkyl (2-18C) alkenyl, aryl or (7-8C) aralkyl, R' may also be H, aromatic rings may be substd. by hal, (1-18C) alkyl, (1-18C) o-alkyl, and alkyl gps. may be substd. by OH, or NR'R2 forms a heterocyclic ring opt. contng. another heteroatom; R = H, OH or NH2). Salts of (I) are also included. (I) influence glycolysis, lypolysis, and hormone exchange. The ratio of phosphorylase:lysase activation is very high. Also used for "energy mobilising" e.g. for treatment of shock, as anti-metabolites, e.g. for immono-suppression, sedatives and narcotic potentiators and positive inotropics.
Patent CH-545662-A (CH)
Title: Forming metal strip into shaped hollow sections - from partial profiles in a single operation
IPC: E06B3/273
Filed: 1970-12-09
Abstract: The parent patent described process of forming >=2 metal strips on shaping tools into partial profiles whose lateral edges are connected by joints obtd. by bending into a shaped hollow section in a single operation. The improvement consists in that >=1 metal strip, on >=1 of its surfaces, or in its entirety, is of a different material from that of the other strip(s), whicha re pref. Al. (Stainless) steel or a synthetic material may be used with Al to form the hollow section.
Patent GB-2344602-A (GB)
Title: Variable-flush facility for siphon-discharge cistern
Inventor: GESEK BOGDAN
IPC: E03D1/14
Filed: 1996-07-16
Abstract: A cistern for use with a water closet has a conventional flushing lever 26 which when depressed initiates the siphonic action which empties the cistern. The siphon 16 is an inverted U-tube and at the top of the first limb 20 of the U-tube is a rotary valve which allows a controlled flow of air to enter the limb 20 during flushing and thereby destroy the vacuum in the U-tube to terminate the flushing cycle. The rotary valve has a number of settings to allow the duration of the flushing cycle to be varied, and is controlled from outside the cistern.
Patent GB-2347460-A (GB)
Title: Safe with telescopically adjustable body and cover
Inventor: BROADBRIDGE ALAN CLIVE
IPC: E05G1/00
Filed: 2000-02-21
Abstract: The safe includes outer and inner body parts (12, 13) which are telescopically engaged such that, in use, the length of the safe may be changed and outer and inner cover parts (Fig 14 ref. 39, Fig 10 ref. 38) which are also telescopically engaged and are adjustable to correspond to length of the safe. Each of the body parts comprises an internal ledge located on each side wall where equally spaced holes (Fig. 6 ref. 35) are located on the ledges of the inner body part and two spaced pairs of holes (Fig. 3 ref. 24) are located on the opposite ends of the ledges of the outer body part and a nut and bolt (37) can be used to fasten the body parts together when the holes are aligned. The cover parts are formed and adjusted in a similar manner to the body parts. A locking means (51) is located on the underside of the cover and includes a locking member (52) which is extendable under a interior flange (34) located on the body of the safe in order to lock the cover to the body. In use, the safe is adjustable to fill the space between two joists (10), and is fitted between the joists by means of a T piece (11) located between each end of the safe and the joist. Fastening means are fitted through each end of the safe and extend through hole in the T piece into the joist to secure the safe in place.
Patent GB-2360792-A (GB)
Title: Laundry treatment composition containing a rebuild agent
Inventor: HOPKINSON ANDREW
IPC: C11D3/22
Filed: 2000-03-29
Abstract: A laundry treatment composition comprises a water-soluble or water-dispersible rebuild agent for deposition onto a fabric during a treatment process wherein the material undergoes during the treatment process, a chemical change by which change the affinity of the material for the fabric is increased; and a cellulose-crosslinking and/or reactive polymer. The rebuild agent has a polymeric backbone, eg. cellulose or another polysaccharide, and ester-linked pendant groups.
Patent GB-2366344-A (GB)
Title: Hose
Inventor: RIDOLFI MATTHEW VERNON
IPC: F16L33/23
Filed: 2000-06-12
Abstract: A hose 10 comprises a tubular body 12 of flexible material arranged between an inner and an outer helically wound wire 22,24. The hose 10 further comprises a cured resin matrix (26<U>a</U>, figure 3) forming part of an insulation layer 26 within which the outer wire 24 is at least partially embedded. The matrix (26<U>a</U>, figure 3), improves the flexing capabilities of the hose, as it helps to maintain the outer wire 24 in the correct position. The resin matrix (26<U>a</U>, figure 3) is preferably a polyurethane. The hose 10 is preferably used for transporting cryogenic fluids.
Patent GB-2368017-A (GB)
Title: Electric leg stimulator for treating drop foot
Inventor: SWAIN IAN DOUGLAS
IPC: A61N1/36
Filed: 2000-06-20
Abstract: A muscle stimulator device suitable for treating drop-foot comprises two stimulation electrodes 36, 38 fixed to the lower leg and connected to a control unit 40. A resistive pressure switch 100 is also connected to the control unit, and the switch senses root rise and fall to control the timing of stimulation pulses sent to the leg electrodes (see figures 2,3,4). The switch is preferably connected to a tracking comparator (106 fig.7a) in the control unit, so that changes in the resistance characteristics of the switch cause a corresponding adjustment of a response threshold. The length of each stimulation may be fixed or adaptive to the foot rise and fall times. The apparatus may feature a sleep mode.
Patent GB-2367216-A (GB)
Title: Selection of content for downloading to a mobile device
Inventor: SPRATT MICHAEL PETER
IPC: G06F17/30
Filed: 2000-09-26
Abstract: The use of content items (for example the playback of music) downloaded to a mobile device is monitored at the device in order to derive usage data based on categories of items. The usage data is used to derive a category based user preference profile. Subsequent downloading of content items to the device from a server is then controlled on the basis of the preference profile and the categorisation of the content items available from the server. The mobile device may receive content items through a data-capable bearer service of a cellular radio network connecting with the Internet. Alternatively the mobile device may receive content items through a cradle connected to the Internet or through a PC connected to the Internet. Preference profiles may be tailored to different times of the day or week. A user may select items for use with a speech input interface and speech recogniser in the mobile device.
Patent GB-2370013-A (GB)
Title: Furniture panel manufacture
Inventor: CAFFREY PAUL
IPC: B27D5/00
Filed: 2000-12-15
Abstract: A furniture panel 1 comprises a panel of medium density fibreboard with a decorative paper foil 2 laminated to at least one face. An embossing die 20 is placed on bed 22 and heated from 100-130{. The panel is placed on the die and pressure applied (>50 bar for less than 30 seconds) to emboss the paper foil and underlying fibreboard. The edges of the panel may be chamfered and a finishing foil applied to the chamfered edge. A shaped roller (41) is disclosed for this purpose. The die may be equipped with spacer shims or slidable stops to enable different panel sizes to be secured on the die.
Patent GB-2359070-A (GB)
Title: Closure for sampling device
Inventor: WOOLFENDEN ELIZABETH ANGELA
IPC: B01L3/14
Filed: 2000-12-19
Abstract: In a sampling device comprising a sampling tube and a closure, a helical channel formed in a surface of the tube or of the closure provides a passage for gas between the interior and exterior of the tube. In one embodiment the closure comprises a cap having a sleeve 14 and an insert 24, and the helical channel 26 is formed in either the outer surface of the insert or the inner surface of the sleeve. A seal between the cap and the sampling tube is provided by an O-ring seal 18. Alternatively the closure comprises an insert, and the helical channel is formed in the outer surface of the insert or the inner surface of the tube wall.