baber/WOPTO huggingface dataset:
Patent EP-2165702-B1 (EP)
Inventor: GINDULLIS FRANK DR
IPC: A61K9/20
Filed: 2008-09-17
Granted: 2011-11-16
Abstract: The present invention relates to new pharmaceutical compositions in which Candesartan cilexetil is contained in a stabilized form with enhanced solubility and from which it is readily bioavailable when applied in conventional pharmaceutical dosage forms, and a process for the preparation of the same as well as of kits containing such compositions. The pharmaceutical compositions of Candesartan cilexetil or of its combinations with other active ingredients can be used in methods to treat subjects suffering from cardiovascular diseases.
Patent EP-2008657-B1 (EP)
Inventor: SCHULER WALTER
IPC: A61K31/436
Filed: 1997-03-26
Granted: 2013-04-24
Abstract: Use of 40-O-(2-hydroxy)ethyl-rapamycin, optionally in combination with cyclosporin A, FK-506, azathioprine, methotrexate; mycophenolic acid; mycophenolate mofetil; 15-deoxyspergualine, CTLA4-Ig, or monoclonal antibodies to leukocyte receptors or their ligands; for preventing or treating neointimal proliferation and thickening, e.g. including graft vessel disease and restenosis and/or vascular occlusion following vascular injury.
Patent EP-1971196-B1 (EP)
Inventor: KEHRET WILLIAM
IPC: H05K7/20
Filed: 2008-01-22
Granted: 2010-11-24
Abstract: A clamshell enclosure (102) is disclosed for providing thermal and kinetic management for an enclosed electronic circuit. The clamshell enclosure comprises a sealed clamshell casing (102) containing the circuit, and a cover (104) that in combination with a wall of the clamshell casing forms a duct (105). A heat exchanger (110) conducts heat from the electronic circuit inside the clamshell casing to a thermal interface element located within the duct, and a thermally conductive gas moving through the duct comes into contact with the interface element (106), dispelling the heat and thereby cooling the enclosed electronic circuit. A cellular topology of the clamshell casing and of the cover provides stiffness to the enclosure and reduces the effects of shock and vibration on the enclosed electronic circuit.
Patent EP-1962129-B1 (EP)
Inventor: BAYRLE REINER
IPC: G02F1/1343
Filed: 2008-02-14
Granted: 2009-08-05
Abstract: The liquid-crystal display indicating element has z lined supply line (Z1 to Z5) that is arranged in a level on an inside of a cover disk (1). The z lined supply line is guided between two s column electrodes (SE1 to SE5). An individual line electrode has multiple pixel sections (30), which forms the crossing ranges of the line electrodes (ZE1 to ZE5) with the column electrodes. The adjacent pixel sections are electrically connected with each other by connecting sections in each case. The connecting sections are small than the pixel sections. An independent claim is also included for a liquid crystal display indicating panel, which has multiple liquid crystal display indicating elements.
Patent EP-2000104-B1 (EP)
Inventor: IANNARONE RONALD C
IPC: A61B17/16
Filed: 2008-06-05
Granted: 2010-05-19
Abstract: An instrument for retrograde cutting of sockets or tunnels in bone for arthroscopic tenodesis. The instrument is a retrograde cutter used to form a recipient site socket from the inside out, i.e., using a retrograde technique, with minimal incisions of distal cortices and reduced intraarticular bone fragmentation of tunnel rims. The retrograde cutter is provided with a cutting blade that is configured to engage the shaft of the instrument and to lock onto the shaft.
Patent EP-2011565-B1 (EP)
Inventor: SIMMONET JEAN-THIERRY
IPC: B01J13/14
Filed: 2008-07-04
Granted: 2010-11-03
Abstract: Preparation of a suspension of core/shell type capsule comprises: (a) preparing a heterogeneous mixture, at room temperature, comprising an oil phase and water- and oil-immiscible polymers; (b) homogenizing the oil phase and polymers by heating at a homogenization temperature (T h); (c) dispersing, at T h, the homogeneous mixture in an aqueous phase to obtain a direct pre-emulsion; (d) subjecting the pre-emulsion to a set of shearing forces; (e) cooling the emulsion at a temperature favorable for the coacervation of the polymers; and (f) cooling the obtained suspension. Preparation of a suspension of core/shell type capsule comprises: (a) preparing a heterogeneous mixture, at room temperature, comprising an oil phase and water- and oil-immiscible polymers, where at least one polymer is an oligomer having a molecular weight of less than 10000 and a hydroxyl index of >= 10 mg potassium hydroxide/g; (b) homogenizing the oil phase and polymers of the mixture obtained from step (a), by heating at a homogenization temperature (T h), which is less than 100[deg] C, and the mixture has a viscosity = 17 mPa.s -> 1>at T h; (c) dispersing, at T h, the homogeneous mixture obtained from step (b) in an aqueous phase to obtain a direct pre-emulsion, where the oil phase of the pre-emulsion comprises the polymers; (d) subjecting the pre-emulsion to a set of shearing forces suitable to reduce the particle diameter of the dispersed mixture to an average size = 50 mu m; (e) cooling the emulsion obtained from step (d) at a temperature (T c) favorable for the coacervation of the polymers and coating the oil drops by the coacervates; and (f) cooling the suspension obtained from step (e) at a temperature (T p) favorable for the formation of capsules by precipitation and/or crystallization of coacervates, where the oil phase is favorable for the formation of a homogeneous mixture with the polymers at T h, and for the manifestation of the phenomenon of polymer coacervation at T c. Independent claims are included for capsules and aqueous suspension obtained by the method.
Patent EP-2132167-B1 (EP)
Inventor: VOGELBACHER UWE JOSEF
IPC: C07C253/30
Filed: 2008-02-29
Granted: 2013-12-25
Abstract: The present invention relates to a process for preparing beta-ketonitriles of the general formula I in which R1 is, inter alia, C1-C12-alkyl, C2-C12-alkenyl, C2-C12-alkinyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C4-alkyl, phenyl-C1-C4-alkyl, phenoxy-C1-C4-alkyl or benzyloxy-C1-C4-alkyl; R2 is, inter alia, hydrogen, C1-C12-alkyl, C2-C12-alkenyl, C2-C12-alkinyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C4-alkyl, phenyl, phenyl-C1-C4-alkyl, phenoxy-C1-C4-alkyl or benzyloxy-C1-C4-alkyl, which comprises reacting a nitrile of the formula II in which R1 has one of the meanings given above with a carboxylic ester of the formula III in which R2 has one of the meanings given above and R3 is C1-C12-alkyl, C1-C4-alkoxy-C1-C4-alkyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C4-alkyl, phenyl-C1-C4-alkyl, phenoxy-C1-C4-alkyl or benzyloxy-C1-C4-alkyl, where the reaction is carried out in the presence of a potassium alkoxide and at least 80% of the nitrile of the formula II are added to the reaction under reaction conditions.
Patent EP-2160391-B1 (EP)
Inventor: PAZENOK SERGII
IPC: C07D413/04
Filed: 2008-05-28
Granted: 2010-08-04
Abstract: The nicotinamide compounds are new. The nicotinamide compound having general formula (I), preferably general formula (II), is new. In general formula (I), X 1>F, Cl, Br, I, SCN or S-R 3>, where R 3>=H, 1-6C alkyl, 3-6C cycloalkyl, -(CH 2) r-C 6H 5, where r=0-6, where the alkyl residue -(CH 2) r is substituted.; R 1>halogen, cyano, thiocyanato or halogen is substituted with alkyl, alkenyl, alkinyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, alkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl, aryl, heteroaryl, cycloalkyl or heterocyclyl, where the alkyl and alkylene has 1-6C, alkenyl and alkinyl containing 2-6C, cycloalkyl contains 3-6C atoms and the aryl group has 6-10C; n : 0-2, preferably 0-1, particularly 0; R 2>1-6C alkyl, 2-6C alkenyl, 2-6C alkinyl, 3-6C cycloalkyl, which is substituted single or multiple times, directly or differently with halogen, cyano, nitro, 1-4C alkoxy, 1-4C haloalkoxy, 1-4C alkylthio, 1-4C alkylsulfinyl, 1-4C alkylsulfonyl, (1-6C alkoxy)carbonyl, (1-6C alkyl)carbonyl or 3-6C trialkylsilyl; and m : 0-4, preferably 0-2, particularly 0. In general formula (II),R 1>,R 2>,m and n=same as variable group R 1>,R 2>,m and n of general formula (I). Independent claims are included for: (1) a method for producing a nicotinamide compound; and (2) a method for producing a compound of general formula (III), which involves converting a hydroxamic acid compound of general formula (IV) with ethylene oxide of general formula (V) in water and acetone, methanol, ethanol, N,N-dimethylformamide or acetonitrile. R : aromatic, cyclic, heteroaromatic, heterocyclic or aliphatic organic residue; and R 2> and m : same as variable group R 2> and m of general formula (I). [Image] [Image] [Image] [Image] [Image].
Patent EP-2074995-B1 (EP)
Inventor: SCHAFER PETER H
IPC: A61P11/06
Filed: 2003-03-20
Granted: 2016-11-02
Abstract: Discussed is stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable polymorph, salt, solvate or hydrate thereof, as well as a pharmaceutical composition or single unit dosage form comprising such compound and such compound for use as a medicine.
Patent EP-2161052-B1 (EP)
Inventor: BREHM WINFRIED
IPC: A61J1/05
Filed: 2002-03-11
Granted: 2013-02-27
Abstract: The invention relates to the field of connectors for connecting a container with a fluid preparation device for preparing a fluid, in particular a container with a concentrate for the preparation of dialysis fluid. In order to simplify the handling during both the manufacturing process of such containers and the connection of such containers to the fluid preparation devices, the invention proposes a design of a connector (1) for connecting a first and second fluid line of the container with a third and fourth fluid line of the fluid preparation device with two lateraly spaced-apart mounting means (2, 4) which each incorporate one of two orifices (3, 5) terminating the first and second fluid lines. The invention also concerns a corresponding container and fluid preparation device.
Patent EP-2215967-B1 (EP)
Inventor: BETTEGA REMO
IPC: A61B6/10
Filed: 2009-09-07
Granted: 2011-11-30
Abstract: The protector (10) has a jaw part (20), and a tongue part (50) for holding down tongue of a patient, where the tongue part is connected with the jaw part. The jaw part comprises an opening (22) for visual inspection of tongue position of the patient. The jaw part is formed in toothed arc-shape, where caudal edge of the jaw part is split by a gap (24) extending from the opening. Connection between the jaw part and the tongue part is detachable, where the detachable connection is formed according to kind of a cavity positive part system.
Patent EP-2119218-B1 (EP)
Inventor: PFLUGHOEFFT MALTE DR
IPC: B42D15/10
Filed: 2009-02-27
Granted: 2011-01-05
Abstract: The invention relates to a printing apparatus (1) and a method for producing preferably individualized printed security and/or valuable products (17). For this purpose, a digital printing device (5) is used which prints at least one first ink formulation (11a) and at least one second ink formulation (13a) that have at least one physical differentiating feature in the printed state. The first and the second ink formulation (11a, 13a) are printed such that first and second printed data is stored on the printed product (17) in such a way that a person visually examining the printed product sees the printed data exclusively as if the at least one second ink formulation (13a) had not been used in the printing process, and the second printed data can be seen using the at least one physical differentiating feature when the printed product (17) is analyzed.
Patent EP-2252763-B1 (EP)
Inventor: SCHEIDER DIETMAR
IPC: E21B19/07
Filed: 2009-02-27
Granted: 2012-01-04
Abstract: The invention relates to a clamping head for an earth-drilling system comprising a hollow shaft (3) through which a drill pipe (9) can be guided, wherein a sleeve (1) is arranged coaxially on the hollow shaft (3) in such a way that it can move relative thereto, said sleeve having at least one widening end region (1b), in particular a downwardly widening end region which particularly widens in a conical shape, and wherein at least two clamping jaws (2) which can move radially with respect to the hollow shaft (3) are mounted in the hollow shaft (3) and/or on the sleeve (1), said clamping jaws being provided at their radially outer end with run-on surfaces (2b) interacting with the widening end region (1b), such that the clamping jaws (2) can be pressed radially inward as a result of the end region (1b) sliding over them and form a first clamping mechanism for a drill pipe (9), in particular such that a torque can be transmitted between the hollow shaft (3) and drill pipe (9) as a result of an interaction between the clamping jaws (2) and drill pipe (9), wherein a second clamping mechanism is provided in the hollow shaft (3) and can be used to secure a drill pipe (9) in the axial direction, in particular in order to draw a drill pipe (9) from the ground in the axial direction.
Patent EP-2250408-B1 (EP)
Inventor: REISCH MATTHIAS
IPC: F16H61/32
Filed: 2009-02-20
Granted: 2011-11-02
Abstract: An arrangement for coupling at least two freewheels independent of an associated shaft of a gear mechanism comprises at least one shifting device that comprises an actuation device and a shifting device. The shifting device can be axially displaced with the actuation device that is arranged at least partially in the shaft.
Patent EP-2307257-B1 (EP)
Inventor: HENRY GILLES
IPC: B62B7/08
Filed: 2009-07-03
Granted: 2013-09-11
Abstract: A foldable stroller that moves between an extended position and stowed position, and which comprises a seat portion, a back, at least three legs, and a rear linkage including at least one rear leg, a front linkage including at least one front leg, a back linkage including at least one back mount and a seat portion mounting and when moving the stroller from the extended position to the stowed position, the lower end of the back leg tilts forward the lower end of the front leg tilts backward, the back is folded against the seat portion, the upper edge of the back coming opposite the front end of the seat portion mounting and the upper end of the front leg.
Patent EP-2202438-B1 (EP)
Inventor: MCLAUGHLIN THOMAS KILPATRICK
IPC: F16L15/04
Filed: 2007-03-21
Granted: 2014-03-05
Abstract: A protective ring for use in a coupling assembly (100), the coupling assembly comprising a coupling body (120) of generally cylindrical shape with a channel therethrough, each end of said coupling body (120) having a thread for threaded mating with a tubular (132,134) so that the coupling assembly (100) may provide a connection between two tubulars (132,134), the protective ring comprising a ring body (140) for positioning adjacent an interior wall of said coupling body (120) between the two ends thereof and located for contact by said two tubulars (132,134), said ring body (140) being generally cylindrical and having a ring channel therethrough,  characterised in that  said protective ring comprises at least one concave area, extending around at least a part of the circumference of said ring body (140) and at least one opening (144b) therein.
Patent EP-2298233-B1 (EP)
Inventor: FORD STEVEN PALMER
IPC: A61F2/08
Filed: 2003-05-01
Granted: 2018-01-17
Abstract: An implantable prosthesis for repairing an abdominal wall defect is disclosed. The implantable prosthesis comprises a multi-layer soft tissue repair patch including a first mesh layer (66), a second mesh layer (68) as well as an adhesion resistant barrier layer (104), the first mesh layer located between the second mesh layer and the barrier layer; and at least one tether (24,26) extending from a side of the repair patch opposite the barrier layer, the at least one tether having a sufficient length to extend from the patch and through the abdominal wall defect when the patch is on one side of the defect, so that a portion of the at least one tether is accessible on the other side of the defect for manipulation from outside a patient's body; a support member provided on the soft tissue repair patch; and at least one tether including a repair fabric that is susceptible to tissue and muscle integration.
Patent EP-2269656-B1 (EP)
Inventor: THORPE PHILIP E
IPC: A61K47/48
Filed: 2003-07-15
Granted: 2014-08-20
Abstract: Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Patent EP-2287373-B1 (EP)
Inventor: FUJIOKA YUICHI
IPC: C01B31/02
Filed: 2003-11-27
Granted: 2012-08-22
Abstract: The present invention relates to a producing method of carbon nanofibers, comprising causing carbon nanofibers to grow on surfaces of particles, the particles having adhered thereto a catalyst component; recovering the particles with grown carbon nanofibers; separating the carbon nanofibers from the surfaces of the particles by a physical process or a chemical process, and recovering the carbon nanofibers, wherein causing the carbon nanofibers to grow is performed by a fluidizing layer reaction process in which the particles are utilized as fluidizing material in a slow fluidizing state, and the particles are violently stirred after reaction termination to separate carbon nanofibers by collision among the particles, and the carbon nanofibers are recovered.
Patent EP-2510056-B1 (EP)
Inventor: DESBOIS PHILIPPE
IPC: C08G69/26
Filed: 2010-12-07
Granted: 2013-12-04
Abstract: Semiaromatic, semicrystalline copolyamide molding compositions, comprising A) from 35 to 100% by weight of a copolyamide composed of a1) from 35 to 69% by weight of units which derive from hexamethylenediamine and from an aromatic dicarboxylic acid having from 8 to 16 carbon atoms, a2) from 31 to 65% by weight of units which derive from 3,3′-dimethyl-4,4′-diaminodicyclohexylmethane and from terephthalic acid, a3) from 0 to 30% by weight of units of a semicrystalline polyamide different from a1) and a2), B) from 0 to 65% by weight of further additives, where the total of the percentages by weight of A) and B) is 100%.
Patent EP-2354513-B1 (EP)
Inventor: SATO YOSHIKAZU
IPC: F01P3/02
Filed: 2011-01-21
Granted: 2012-03-21
Abstract: In a water-cooled four-cycle engine, an engine core (2) including a cylinder block (3), a cylinder head (4) and a first crankcase half body (8a) is formed as a unitary part cast integrally, and a water jacket (40) including a cylinder jacket (40c) and a head jacket (40h) is formed in the engine core (2). In a first side surface (2a) of the engine core (2) which is parallel with an axis (X) of a crankshaft (15), an intake port (5) and a first semi-peripheral portion (40A) of the water jacket (40) are opened and a first lid plate (46) for closing an opening portion (41) of the first semi-peripheral portion (40A) is connected. In a second side surface (2b) of the engine core (2) on a side opposite from the first side surface (2a), an exhaust port (6) and a second semi-peripheral portion (40B) of the water jacket (40) are opened and a second lid plate (47) for closing an opening portion (42) of the second opposite portion (40B) is connected.
Patent EP-2441422-B1 (EP)
Inventor: OHIRO MASAYA
IPC: A61F13/15
Filed: 2002-09-10
Granted: 2013-07-31
Abstract: A process for making a disposable diaper 1 wherein a plurality of backsheets destined to face a garment the wearer puts on are successively connected one to another along respective side edges to form a first web 63. The first web 63 is continuously fed in its longitudinal direction. Tape fastener members 67 extending in the longitudinal direction are fed to the respective backsheets being contiguous one to another in the first web 63 so as to straddle respective lines A corresponding to the side edges of the respective backsheets. Each of the tape fastener members 67 has its longitudinally opposite end portions folded in a Z-shape or an inverted Z-shape. Top sections of these Z-shape and inverted Z-shape are coated on respective under surfaces with a first self-adhesive and bottom sections of these Z-shape and inverted Z-shape are coated on respective under surfaces with a second self-adhesive. The tape fastener member 67 is bonded to the first web 63 by means of the second self-adhesive. The first web 63 and the tape fastener member 67 are simultaneously cut along the line A.
Patent EP-2389248-B1 (EP)
Inventor: KOENNING LUDWIG
IPC: B02C15/00
Filed: 2011-01-18
Granted: 2012-05-30
Abstract: Die erfindungsgemäße Rollenmühle besteht im Wesentlichen aus einem Mahlteller (1), wenigstens einer mit dem Mahlteller in Abrolleingriff stehenden Mahlrolle (2, 3), einem Hauptantriebssystem zum Antreiben von Mahlrolle und/oder Mahlteller sowie einem Hilfsantrieb (60, 61, 62, 63, 64) zum Antreiben des Mahltellers. Der Hilfsantrieb umfasst wenigstens zwei Linearantriebe (61, 62, 63, 64) zum Drehen des Mahltellers und eine Steuereinrichtung (7) zur individuellen Ansteuerung der Linearantriebe im Sinne einer ununterbrochenen Drehbewegung.
Patent EP-0010387-B1 (EP)
IPC: B60N2/50
Filed: 1979-10-05
Granted: 1983-02-16
Abstract: A vehicle seat suspension, of the type comprising a seat frame (12) supported on a base frame (11) by two spaced pairs of scissor action linkage arms (13,14), has the ends of the linkage arms connected to one of the frames wholly by pivotal connections (e.g., 15,18) having freedom for displacement longitudinally of the suspension and a resilient coupling (46) connecting the one frame to one of the linkage arms to damp the transmission of vibrations between the frames in the longitudinal direction.
Patent EP-0011494-B1 (EP)
IPC: G11B19/24
Filed: 1979-11-15
Granted: 1984-04-04
Abstract: Method and apparatus for recovering information at a substantially constant rate from a rotable information storage disc (110). The information is stored on the disc (110) in a plurality of substantially circular and concentrically arranged information tracks, with a substantially uniform recording density, and it is recovered by controllably rotating the disc, relative to a transducer (128) at an angular velocity substantially inversely proportional to the radius of the corresponding track. The apparatus includes a coarse speed control potentiometer (130) for producing a measure of the radius of the particular information track from which information is being recovered, and fine speed control means (136) for comparing the relative phase angles of a periodic signal in the recovered information and a periodic reference signal and for producing a fine speed control signal proportional to the phase difference. The measure of radius and the fine speed control signal are summed together and coupled to a voltage-controlled oscillator (132) to produce a composite speed control signal, which is coupled to a servo (134) to rotate the disc (110) at a corresponding angular velocity.
Patent EP-0015906-B1 (EP)
Title: Boite pour cigares ou cigarettes
IPC: A24F15/20
Filed: 1979-08-28
Granted: 1982-06-16
Abstract: La boite pour cigares ou cigarettes possede un couvercle (3) coulissant dans le sens de la longueur du corps (1) de la boite. Pour soulever l'extremite d'un cigare ou d'une cigarette lorsque le couvercle est partiellement retire, il est prevu une piece constituee par un fil de fer en forme d'etrier (4) dont les extremites sont introduites dans la boite; les montants de cette piece sont rabattus, en fermant le couvercle, dans des encoches (6) faites dans le corps de la boite: mais, en repoussant le couvercle vers l'arriere, cette piece en forme d'etrier s'incline vers le haut.