baber/WOPTO huggingface dataset:
Patent MX-153625-A (MX)
Inventor: STEWART RAY F
IPC: F16L58/00
Filed: 1982-06-11
Abstract: Methods of preventing corrosion in which current flows between the to-be-protected substrate and a distributed electrode whose electrochemically active surface provided by an element which is composed of a conductive polymer and which is at least 500 microns thick. In one embodiment, the electrode is a flexible strip comprising a highly conductive core, eg. of copper, and a conductive polymer element surrounding the core. In another embodiment, the electrode is a conductive polymer layer which conforms to the surface of the substrate but is separated from it by a layer of insulation.
Patent NZ-182810-A (NZ)
Title: Solid stable choline salicylate compositions
Inventor: SASMOR E
IPC: A61K47/12
Filed: 1976-12-06
Abstract: Novel cholinesalicylate-carboxy-lower alkyl-cellulose-metal complexes are obtained by forming an aqueous solution of a carboxy-lower alkyl-cellulose and cholinesalicylate, adding a source of a physiologically tolerated, at least doubly charged, metal ion in a quantity such that a complex is formed of the components, allowing the reaction mixture to stand until it thickens, and subsequently drying it. The novel compounds are stable, pharmaceutically active, cholinesalicylate compounds.
Patent NZ-201437-A (NZ)
Title: Piperazine derivatives of theobromine(3,7-
Inventor: FAVIER C
IPC: C07D473/10
Filed: 1982-07-30
Abstract: New compounds of the formula   <IMAGE>(I)  <IMAGE>  and the pharmaceutically acceptable acid addition salts thereof, wherein Z1 and Z2 are each independently selected from the group consisting of CH2, CHOB and C=O, wherein B is selected from the group consisting of hydrogen and alkanoyl; Y is oxygen or sulfur; n is an integer from 0-4 but cannot be zero when Z1 is CHOB; m is an integer from 0-4 but cannot be zero when Z2 is CHOB; and R1, R2 and R3 are each independently hydrogen, halogen, hydroxy, trifluoromethyl, alkyl or alkoxy; are antihistamines and are therefore useful in the treatment of respiratory diseases including asthma, hay fever, allergies and the common cold.
Patent NZ-208387-A (NZ)
Title: Manufacture of organic nitrites
Inventor: STIFF A J
IPC: C07C203/02
Filed: 1984-06-05
Abstract: The invention concerns a process for the preparation of nitric acid esters of organic hydroxy compounds by reacting an organic hydroxy compound with nitric acid in the presence of sulphuric acid and in a solvent, followed by separating off the spent acid, substantially neutralizing the residual acidity of the organic solution, and removing solvent to leave the organic nitrate. From 95% to 220% of the stoichiometric requirement of nitric acid for complete nitration is used. The mole ratio of water to sulphuric acid at the end of the reaction is from 0,2:1 to 2,5:1. From 200 to 2000 ml of solvent per mole of hydroxy group is present. Yields of at least 92% are obtained. The invention is particularly suitable for the preparation of alkyl nitrates, alkylene or polyalkylene glycol, monoalkyl ether mononitrates, alkylene or polyalkylene glycol dinitrates, diol nitrates, nitrates containing homocyclic or heterocyclic rings, or nitrates derived from polyols.
Patent NZ-224946-A (NZ)
Title: Substituted benzothiazole derivatives and pharmaceutical compositions
Inventor: SHINYA ABE
IPC: C07D277/84
Filed: 1988-06-08
Abstract: A benzothiazole compound having the formula below and pharmaceutical compositions containing it are disclosed which are effective to inhibit the production of leukotriene. The compounds can be used for the making of medicaments effective against allergy, asthma, affections of the skin, allergic rhinitis and affection of a cardiovascular system, <CHEM> in which R20 is ester or amide and -NR5R6 is amino in variety.
Patent NZ-225599-A (NZ)
Title: Antibody-enzyme conjugates and combinations with prodrugs for the treatment of tumour cells
Inventor: SENTER PETER D
IPC: C12N9/84
Filed: 1988-07-28
Abstract: This invention relates to anthracycline prodrugs allowing the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and the additional administration of the prodrug that is converted at the tumor site, in the presence of the antibody-bound enzyme, to an active cytotoxic drug. The present invention also relates to a method for preparing these prodrugs. According to one embodiment of the invention, an antibody-enzyme conjugate containing the enzyme, penicillin V amidase ("PVA"), has been used in conjunction with a novel prodrug, N-(p-hydroxyphenoxyacetyl)adriamycin to effect killing of tumor cells. The products of this invention provide for enhanced selective killing of tumor cells and are thus useful in the treatment of cancers and other tumors.
Patent NZ-233886-A (NZ)
Title: Method of preparing polymer sequences (e.g. peptides) involving activators to remove protecting groups, apparatus therefor and substrates with 10 3 or more different ligands
Inventor: PIRRUNG MICHAEL C
IPC: C12Q1/68
Filed: 1990-05-31
Abstract: A detection apparatus for determining a fluorescence pattern on a substrate and capable of discriminating an area exhibiting fluorescence of less than about 2.5x10<4>  mu m<2>, said apparatus comprising a light source for directing light at the substrate, means for detecting fluoresced light from the substrate, and means for determining the location of the fluorescent light.
Patent NZ-240871-A (NZ)
Title: Fungicides containing substituted 1,2,4-triazole-1-propane nitrile
Inventor: LEIGHTLEY LIAM EDWARD
IPC: D06M13/348
Filed: 1991-12-05
Abstract: Specific triazoles discovered to be useful as fungicides are:   1.  alpha -n-butyl - alpha -phenyl-1H-1,2,4-triazole-1-propanenitrile     2.  alpha , alpha -diphenyl-1H-1,2,4-triazole-1-propanenitrile 3.  alpha -benzyl- alpha -phenyl-1H-1,2,4-triazole-1-propanenitrile   4.  alpha -n-butyl- alpha -2-methoxyphenyl-1H-1,2,4-triazole-1-propanenitrile 5.  alpha -n-butyl- alpha -4-fluorophenyl-1H-1,2,4-triazole-1-propanenitrile 6.  alpha -phenyl- alpha -(2-phenylethyl)-1H-1,2,4-triazole-1-propanenitrile 7.  alpha -(4-fluorophenyl)- alpha -n-propyl-1H-1,2,4-triazole-1-propanenitrile 8.  alpha - [2-(4-chlorophenyl)ethyl]- alpha -phenyl-1H-1,2,4-triazole-1- propanenitrile 9.  alpha -n-butyl- alpha -4-chlorophenyl-1H-1,2,4-triazole-1-propanenitrile   The materials which the fungicidal triazoles are capable of protecting include, for example, wood, fabric, leather, coatings, and caulks. Especially when wood is being protected from attack by fungi we prefer compositions comprising the triazole(s) and a quaternary ammonium compound
Patent NZ-244124-A (NZ)
Title: Dna sequence encoding synthetic trna and methods of preparing trna cys (aaa), trna ser (aaa) trna ala (aaa)
Inventor: HARDESTY BOYD
IPC: C07H21/04
Filed: 1992-08-28
Abstract: Synthetic tRNAs are produced from tRNACys(AAA), tRNASer(AAA), tRNAeAla(AAA), and tRNAiAla(AAA) genes. Polyuridylic acid-dependent syntheses of polypeptides were carried out in vitro on E. coli ribosomes using the synthetic tRNAs.
Patent NZ-247974-A (NZ)
Title: Imidazole-substituted cyclohexane derivatives; pharmaceutical compositions
Inventor: MULLER ULRICH E
IPC: C07D233/68
Filed: 1993-06-24
Abstract: Imidazolyl-substituted cyclohexane derivatives are prepared by reaction of corresponding cyclohexane derivatives with substituted imidazoles and subsequent variation of the substituents. The imidazolyl-substituted cyclohexane derivatives can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
Patent NZ-250933-A (NZ)
Title: The octapeptide amide angiopeptin, pharmaceutical compositions and preparation
Inventor: FAUCHERE JEAN-LUC
IPC: A61K38/00
Filed: 1994-02-21
Abstract: The invention relates to the derivatives of formula (I): <IMAGE>  in which R1, R2, X1 and X2 are defined as in the description. Medicaments.
Patent NZ-256796-A (NZ)
Title: Estrene steroid-containing medicament for nasal administration
Inventor: BERLINER DAVID L
IPC: A61K31/56
Filed: 1993-09-28
Abstract: The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human semiochemical, e.g. an Estrene steroid, or a pharmaceutical composition containing an Estrene steroid, such that the ligand semiochemical binds to a specific neuroepithelial receptor. The steroid is preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. Other embodiments of the invention include pharmaceutical compositions containing the steroids.
Patent NZ-314194-A (NZ)
Title: Papermaker's fabric comprising machine-direction yarns interwoven with cross-machine yarns
Inventor: JOSEF MICHAEL J
IPC: D21F7/08
Filed: 1997-02-05
Abstract: A papermaker's fabric includes a system of machine-direction (MD) yarns interwoven with a system of cross-machine direction (CD) yarns. The MD yarns are pairs of a first MD yarn and a second MD yarn. The first and second MD yarns are of a substantially rectangular cross section having identical width and thickness. The first and second MD yarns of each pair weave side-by-side as a single yarn with the CD yarns through the fabric. The CD yarns are of circular cross section. The fabric has a permeability to air less than 150 cubic feet per minute per square foot at 0.5 inch H2O-pressure. <IMAGE>
Patent NZ-332335-A (NZ)
Title: Self-closing liquid distribution valve retainable in open position
Inventor: ERB RENE
IPC: F16K21/04
Filed: 1997-03-25
Abstract: PCT No. PCT/FR97/00529 Sec. 371 Date Sep. 23, 1998 Sec. 102(e) Date Sep. 23, 1998 PCT Filed Mar. 25, 1997 PCT Pub. No. WO97/35802 PCT Pub. Date Oct. 2, 1997A self-closing liquid distribution valve, particularly for esculent liquids, essentially consisting of a body (1) for mounting the valve in the opening of a container, and a liquid release plunger (2) engaging a resilient sealing membrane (3) secured to the body (1). The valve is provided with elements (4',4'') for retaining the plunger (2) in the open position.
Patent NZ-333376-A (NZ)
Title: Haemophilus adherence and penetration proteins and vaccines therefrom
IPC: A61K39/02
Filed: 1995-08-16
Abstract: The specification describes the use a haemophilus adhesion and penetration protein in a vaccine.
Patent NZ-334166-A (NZ)
Title: Airline seat, seat, back and leg rest reclinable to form flat sleeping surface
Inventor: DRYBURGH IAN
IPC: B60N2/90
Filed: 1995-12-11
Abstract: A seating unit (1) comprises a fixed housing (10) containing a primary seat with a reclinable back arranged to recline in such a manner that it remains within the housing. The seating unit is suitable for a aircraft cabin and may further comprise a leg-rest arranged to cooperate with the seating portion to form part of a substantially flat surface when the back is reclined in a substantially horizontal position. The seating unit may further comprise a secondary seat (3) positioned to face the primary seat, the secondary seat having a seating portion positioned to cooperate with the leg-rest of the primary seat to form a portion of the substantially flat surface when the back of the primary seat is reclined in the substantially horizontal position. Privacy between seats and use of available space within an aircraft cabin may be optimised by arranging at least some of the seats in an echelon.
Patent NZ-335650-A (NZ)
Title: Method for controlling insects by using a microemulsion comprising hydrocarbon solvent, surfactant and water
Inventor: HAGARTY JOHN D
IPC: A01N25/30
Filed: 1997-12-18
Abstract: Microemulsion insecticides that do not contain conventional actives kill insects by an oil/surfactant combination that when applied to the surface of a crawling insect cause it to flip over onto its back.  The microemulsion includes 20% to 60% by weight of a hydrocarbon solvent, 1% to 20% by weight of a surfactant, and at least 10% by weight of water.  The conventional actives that are not included in the microemulsion are insecticidally active synthetic pyrethroids, pyrethrum, organophosphates, carbamates, chlorinated hydrocarbons, and heterocyclics.
Patent NZ-336994-A (NZ)
Title: Method for producing regular porous cellulose pearls with particle size 2 and 50 micrometers
Inventor: BEYER CHRISTINE
IPC: C08J3/16
Filed: 1998-12-09
Abstract: Process for producing regular porous pearl cellulose with a particle size in the range from 2 to 1000 mm, wherein (a) a cellulose having a degree of polymerisation in the range from 150 to 2000 is dissolved in a solvent to form a solution of 0.5 to 25% by mass cellulose, (b) the cellulose solution is finely divided and dispersed in a dispersant which is immiscible with the solution and has a viscosity in the range from 10 to 80000 mPa.s, (c) the dispersed solution particles by precipitating with a liquid precipitating agent miscible with the solvent (1) after cooling the dispersion to below the melting temperature of the cellulose solution from the dispersant or (2) directly in the dispersion, and (d) the pearl particles are separated from the liquid mixture of solvent,  precipitating agent and possibly dispersant.
Patent NZ-507692-A (NZ)
Title: Retroamide chain benzofuran and benzothiophene compounds substituted by amides or carbamates for use in melatonergic system disorders
Inventor: DELAGRANGE PHILIPPE
IPC: A61K31/55
Filed: 1999-05-10
Abstract: A compound of the general formula R-A-R' for use in the treatment of seasonal affective disorder, sleep disorder, cardiovascular pathologies, insomnia and fatigue resulting from jet-lag, appetite disorders and obesity. Wherein; A represents a ring system of Formula (II), (III) or (IV); R represents a group of formula (V), (VI), (VII) or (VIII); and R' represents a group of Formula (IX), wherein R5 represents a group of Formula X.
Patent NZ-509178-A (NZ)
Title: Compositions and methods for therapy and diagnosis of prostate cancer
Inventor: MITCHAM JENNIFER LYNN
IPC: A61P35/00
Filed: 1999-07-14
Abstract: An isolated polypeptide comprising at least an immunogenic portion of a prostate tumor protein, or a functional variant thereof, wherein the tumor protein comprises the amino acid sequence recited in SEQ ID NO: 337 or an amino acid sequence that is encoded by a polynucleotide sequence selected from the group consisting of: (a) a polynucleotide sequence that encodes the sequence recited in SEQ ID NO: 337; (b) sequences that hybridize to (a) under highly stringent conditions; and (c) complements of any of the sequence of (a) or (b), the use thereof in the preparation of vaccines; the use thereof in the preparation of T cells specific for a prostate tumor protein; the use thereof in treating tumors.
Patent NZ-511760-A (NZ)
Title: Methods for the production of TcR gamma delta T cells
Inventor: BELL DAVID NICHOLSON
IPC: C12N5/02
Filed: 1999-11-04
Abstract: The method for obtaining and expanding TcRgd+ T cells in culture is described. The method involves: 1) culturing cells from a sample containing TcRgd+ T cells or precursors thereof in a first culture medium comprising a T cell mitogen and at least two cytokines and 2) culturing the cells obtained in step 1) in a second culture medium comprising at least two cytokines. Preferably, the method comprises 1) culturing the cells in a first culture medium comprising (a) a T cell mitogen, (b) interleukin-2 and (c) interleukin-4; and 2) culturing the cells obtained in step 1) in a second culture medium comprising (i) interleukin-2 and (ii) interleukin-4 to obtain TcRgd+ T cells. The medium used to culture the TcRgd+ T cells in step 1) may alternatively be a conditioned medium prepared by stimulating umbilical cord blood cells with a T cell mitogen. The TcRgd+ T cells obtained by the method can be used in a variety of experimental, therapeutic and commercial applications.
Patent NZ-514334-A (NZ)
Title: Antimicrobial acid center cleaner for use on organic or food soil
Inventor: HERDT BRANDON L
IPC: C11D7/26
Filed: 2000-03-09
Abstract: A low foaming acid cleaner composition is disclosed which comprises:  (a) about 1 to 80 wt % of phosphoric acid;  (b) about 0.1 to 40 wt % of an organic carboxylic acid;  (c) about 0.1 to 40 wt % of a solvent comprising a hydrocarbon ether or a hydrocarbon alcohol;  (d) about 0.1 to 40 wt % of a sequestrant;  and (e) about 0.1 to 40 wt % of an ether amine composition comprising the formula: [R1-O-R2]n-N[R]3-n wherein: R is -H, -R1 or -R2-NH2, R1 is a C1-24 alkyl group, R2 is a C1-6 alkylene group and n is 1 or 2;  and (f) about 0.1 to 80 wt% water;  wherein the composition has a pH of 1 to 5 and can remove either carbohydrate or proteinaceous soil from hard surfaces. These compositions are suitable to remove carbohydrate and proteinaceous soils from beverage manufacturing locations such as soils arising in the manufacture of malt beverages, fruit juices, dairy products and such like industries.
Patent NZ-515235-A (NZ)
Title: Pharmaceutical complex
Inventor: BILLOTTE ANNE
IPC: A61K47/48
Filed: 2000-06-02
Abstract: A complex of eletriptan and a cyclodextrin derivative of formula (I), whereinR1a-g, R2a-g and R3a-g each independently represent OH or O(CH2)4SO3H.  Also described are pharmaceutical compositions containing this complex, a process for its preparation and its use in the manufacture of medicaments for the treatment or prevention of migraines or a disease for which a 5HT1B/1D receptor agonist is indicated.
Patent NZ-515793-A (NZ)
Title: Three step method for imparting shrink-resistance on animal fibers involving at two step oxidation then reduction cleavage of the cystine disulfide bond
Inventor: ICHIMURA HISASHI
IPC: D06M11/50
Filed: 2001-11-28
Abstract: Disclosed is an animal fiber with scales, such as wool, mohair, alpaca, cashmere, llama, vicuna or angora, with reduced shrinkage.  Such fibers have a degree of oxidization of a --S-S- bond in an epidermal cell of the animal fiber of not less than 0.1 of relative absorbance in an absorption band of -SO3H group and/or not less than 0.8 of relative absorbance in an absorption band of -S-S)3Na group with an absorbance of an absorption band corresponding to amide I set to 1 in a reflection FT-IR measuring method, they show shrink proofing of an area shrinkage rate of not more than 8% in three hours aqueous washing when measures as a felting shrinkage rate in conformity with Wool Mark Test Method 31, and have pilling resistance of not lower than third class in JIS L-1076.6.1A method.  In addition, they retain the original water repellency of the natural animal fiber. Such fibers are made by a method comprising primary oxidation of the -S-S- bond into lower order oxidized state, further oxidation of the -S-S- bond into a di, tri, or tetra-oxidized state, then reduction cleavage of the di, tri, or tetra-oxidized -S-S- bond.
Patent NZ-515956-A (NZ)
Title: Transgenic animals as models for neurodegenerative disease
Inventor: GEERTS HUGO ALFONS GABRIEL
IPC: C12N15/09
Filed: 2000-06-30
Abstract: The application describes a nucleic acid knockin-knockout vector comprising: *A nucleic acid sequence encoding a human Tau protein; *A sequence capable of directing expression of said human Tau protein in the nervous system of a non-human animal; *A targeting sequence comprising a nucleotide sequence exhibiting a sufficient degree of homology with the sequence encoding the equivalent Tau protein in the animal or in the flanking sequences to facilitate integration of the vector via homologous recombination. Several methodologies involving making a transgenic non-human animal using the above vector are also disclosed.
Patent NZ-518566-A (NZ)
Title: Hydroxamic acid derivative as inhibitor of the formation of soluble human CD23
Inventor: FALLER ANDREW
IPC: A61K31/16
Filed: 2000-10-25
Abstract: Compounds of formula (I) wherein, R is isopropyl, n is 0, R1 is naphthylmethyl, R2 is t-butyl and R3 is methyl. The compounds are used in the manufacture of medicaments for the treatment of disorders mediated by s-CD23.
Patent NZ-519694-A (NZ)
Title: Electronic lock where using a signal from the key and having an anti tamper mechanism
Inventor: DAVIS PAUL
IPC: E05B15/00
Filed: 2001-01-17
Abstract: An electronic locking system (10) comprises a cylinder (14) housed within and rotatable with respect to a shell (16). At least one of the key (18) and the cylinder (14) is capable of generating a signal. An electrically powered locking mechanism is housed within the cylinder (14) and includes a lock member (12) movable between an open position and a locked position. The lock member (12) in the locked position interferes with the rotation of the cylinder (14) with respect to the shell. The cylinder (14) further includes an interfering member (90), movable between an interfering and non- interfering position, which resists movement of the locking member (12) when it is in the interfering position. In addition, an anti-tamper mechanism selectively resists movement of the lock member in response to longitudinal movement of the cylinder.
Patent NZ-524853-A (NZ)
Title: Induction of exon skipping in eukaryotic cells
Inventor: VAN OMMEN GARRIT-JAN BOUDEWIJN
IPC: C12N15/09
Filed: 2001-09-21
Abstract: A method for directing splicing of a pre-mRNA in a cell capable of performing splicing operation comprising contacting said pre-mRNA in the cell with an agent capable of specifically inhibiting an exon inclusion signal of at least one exon in the pre-mRNA, said method further comprising allowing splicing and translation of the pre-mRNA wherein the translation results in a mutant of normal dystrophin protein and wherein said exon inclusion signal is present in exon number 2, 8, 43, 44, 45, 46, 50, 5, 52 or 53; a method for decreasing the production of aberrant protein in a cell comprising the method of directing splicing; a method for determining whether a nucleic acid comprising complementarity to part of an exon is capable of specifically inhibiting an exon inclusion signal; a nucleic acid capable of specifically inhibiting an exon inclusion signal; a nucleic acid delivery vehicle; and a non-human animal provided with said nucleic acid.
Patent NZ-526704-A (NZ)
Title: Albumin, heat-denatured, so that it can be a fat replacement with reduced risk of coagulation and/or hydrolysis
Inventor: CAMPBELL LYDIA JOHANNA
IPC: A23L33/20
Filed: 2001-12-19
Abstract: Described is a method for the manufacture of a fat replacement material suitable for use in the manufacture of food products. The method comprises the steps of: a) providing a substantially homogeneous aqueous fluid containing albumin and at least one stabilizer selected from a sugar and salt; b) subjecting the fluid to a controlled heat treatment at a temperature and for a period of time not less and not greater than that sufficient for obtaining from 50 to 100% denaturation of the albumin; and c) spray drying of the heat treated fluid. Also provided is a fat replacement material comprising a spray dried powder comprising an intimate admixture of 1 part by weight of from 50% to 100% denatured albumin, and from 3 to 100 parts by weight of at least one stabilizer selected from a sugar and a salt
Patent NZ-528628-A (NZ)
Title: Periphyton filtration pre- and post-treatment system and method
Inventor: JENSEN KYLE R
IPC: C02F3/32
Filed: 2002-04-19
Abstract: Periphyton filtration is a known method for performing bioremediation of polluted water. The present system (10) cmprises adding a strong oxidizer, such as ozone from an ozone generator (18) to the influent, and in some cases to the effluent to make organically bound nutrients available to a target culture in a periphyton bed (24) or to aquatic plants to reduce the population of undesirable microinvertebrates and to make organically bound nutrients available to the periphyton. A pesticide (P) may be added to control insect populations.
Patent NZ-530348-A (NZ)
Title: Fungicidal composition and use of this composition for controlling plant diseases
Inventor: GARNIER ALAIN JOSEPH JEAN FLOR
IPC: A01N43/54
Filed: 2002-07-24
Abstract: A fungicidal composition comprising at least fungicidal compound of the family anilinopyrimidines and imazalil.