baber/WOPTO huggingface dataset:
Patent FI-854050-A0 (FI)
Inventor: BANNWARTH WILHELM
IPC: C07K1/00
Filed: 1985-10-17
Abstract: 1. Claims for the Contracting States : BE, GB, NL, AT An apparatus for perfoming chemical reaction sequences, characterized by a first number n of reaction discs (1) which are superposed in the form of a stack and are individually displaceable relative to one another, means for defining the displacement in a second number m of identical steps, m continuous bores (11, 14) disposed in the discs at the step distances from one another, one of the bores being widened out per disc to form a reaction chamber (14), means for retaining a support material in the reaction chamber on the flow of a reagent there-through. 1. Claims for the Contracting States : DE, FR, IT, CH, LI, SE An apparatus for performing chemical reaction sequences having a first number n of reaction discs (1) which are superposed in the form of a stack and are individually displaceable relative to one another, means for defining the displacement in a second number m of identical steps, m continuous bores (11, 14) disposed in the discs at the step distances from one another, one of the bores being widened out per disc to form a reaction chamber (14), means for retaining a support material in the reaction chamber on the flow of a reagent therethrough, characterized in that the undersides of the reaction discs have grooves extending concentrically to the bores and containing O-rings.
Patent FI-873324-A0 (FI)
Inventor: KOSSATZ GERT
IPC: C04B41/63
Filed: 1987-07-30
Abstract: Reinforced gypsum boards are produced from gypsum (semi-hydrate), if appropriate reinforcing materials, preferably cellulose particles, polyisocyanates being admixed during the manufacture of gypsum boards and/or being applied to the surface of the gypsum boards. 
<??>The invention also relates to polyurea-modified reinforced gypsum boards of gypsum (semi-hydrate), if appropriate reinforcing materials, preferably cellulose particles, and polyisocyanates, having improved strength, water resistance and flexural strength of the gypsum boards.
Patent FI-874852-A0 (FI)
Inventor: LAM DOMINIC MAN-KIT
IPC: A61K47/48
Filed: 1987-11-03
Abstract: Novel methods and compositions are provided for preventing secondary cataracts. A cytotoxic agent is employed which is instilled into the anterior chamber of the eye to inhibit proliferation of remnant epithelial cells after extracapsular cataract extraction. Desirably a non-cytotoxic agent cross-reactive with the cytotoxic agent is instilled prior to instillation of the cytotoxic agent. The agents can be provided as kits.
Patent FI-883605-A0 (FI)
Inventor: MANNING JAMES H
IPC: D21F11/00
Filed: 1988-08-01
Abstract: A nonwoven fibrous web is disclosed having high wet tensile strength when packed in a preservative liquid load, yet which breaks up under mild agitation conditions in a wet environment such as by the flushing action of a toilet. The wiper includes a nonwoven web made of a special blend of cellulosic fibers held together only by friction and naturally occurring hydrogen bonding. No binder is necessary to hold together the fibers. Derivatization of the fibers is not necessary for their breakapartability. The nonwoven fibrous web is produced by subjecting a wet-laid web of cellulosic fibers to hydroentanglement and drying the web without addition of a bonding agent.
Patent FI-884140-A0 (FI)
Inventor: PLESTER GEORGE
IPC: B07C5/34
Filed: 1988-09-08
Abstract: Methods of discriminating between contaminated and uncontaminated containers prior to washing is disclosed characterized by the testing of the residue of the container to determine if the residue is residue of the original product packed in the container. If the residue is not sufficiently similar to the original product, the container is rejected as contaminated.
Patent FI-890758-A0 (FI)
Inventor: RAESAENEN JARKKO
IPC: G01J3/20
Filed: 1989-02-16
Abstract: An IR-spectrometric analysing procedure, the measuring absorbance and reference absorbance being detected simultaneously from an IR light beam conducted to pass through the sample and diffracted to a spectrum. An IR spectrometer comprising a light source (1), a sample cuvette (5), a diffraction member (6), detectors (7) and a calculating means (9) for determining the content values of the sample corresponding to the measuring absorbance, the detectors (7) having been arranged to detect the measuring absorbance and the reference absorbance simultaneously from the beam that has passed through the sample and been diffracted to a spectrum.
Patent FI-915780-A0 (FI)
Inventor: KUIJPERS WILHELMUS HENRICUS AR
IPC: C07H21/04
Filed: 1991-12-09
Abstract: The invention relates to novel labelled modified oligonucleotides useful for gene therapy, a conjugate of a targeting moiety, such as an antibody and a modified oligonucleotide complementary to the labelled oligonucleotide, the combination of both being useful in therapy of viral infections, tumours and (auto) immunodiseases. Also disclosed are pharmaceutical formalations comprising the various compounds.
Patent FI-923085-A0 (FI)
Inventor: WRIGHT ANDREW FIRMAN
IPC: A61K47/48
Filed: 1992-07-03
Abstract: Conjugates useful for treating gastrointestinal tumours such as colorectal tumours comprises an antibody such as C242 antibody and a toxin such as ricin A. The antibody and toxin may be coupled by a linker. Pharmaceutical compositions containing the conjugates and processes for their preparation are also inculded as well as methods of treating gastrointestinal tumours.
Patent FI-945762-A0 (FI)
Inventor: KAWASHIMA YOICHI
IPC: C07D417/06
Filed: 1994-12-08
Abstract: This invention relates to the compounds of the formula [I] which are useful for the treatment of cataracts, and the synthetic intermediates of the formula [II], <CHEM>  wherein   R<1>   is hydroxy which can be protected by a protective group; R<2>   is lower alkyl; R<3>   is hydrogen, lower alkyl, hydroxy, which can be protected by a protective group, or lower alkoxy, and the said lower alkyl can be substituted by hydroxy, which can be protected by a protective group, amino or lower alkylamino; R<4>   is tetrazolyl, phosphonyl or lower alkyl ester thereof, or sulfonyl or lower alkyl ester thereof, and A   is alkylene.
Patent FI-955658-A0 (FI)
Inventor: VAN DEN BRINK JOHANNES MAARTEN
IPC: C12N15/53
Filed: 1995-11-24
Abstract: PCT No. PCT/NL94/00135 Sec. 371 Date Nov. 28, 1995 Sec. 102(e) Date Nov. 28, 1995 PCT Filed Jun. 10, 1994 PCT Pub. No. WO94/29453 PCT Pub. Date Dec. 22, 1994Disclosed is a new gene which codes for a NADPH cytochrome P450 oxidoreductase from filamentous fungi. Also disclosed are a recombinant DNA molecule which comprises at least a part of that gene, an RNA molecule derived therefrom and a new polypeptide (or protein), as well as at least one host cell transformed with such recombinant DNA molecule. Particularly suitable host cells are those originating from a filamentous fungus. With the polypeptides (proteins) and the host cells according to the invention, new processes for enzymatic conversions can be performed. In particular, enzymatic conversions by means of monooxygenases, more particularly by means of enzymes from the cytochrome P450 superfamily are improved with the invention.
Patent FI-962642-A0 (FI)
Inventor: MELLER WOLFGANG
IPC: G01R25/04
Filed: 1996-06-26
Abstract: PCT No. PCT/DE94/01380 Sec. 371 Date Jun. 3, 1996 Sec. 102(e) Date Jun. 3, 1996 PCT Filed Nov. 23, 1994 PCT Pub. No. WO95/18384 PCT Pub. Date Jul. 6, 1995The digital phase detector detects a phase shift between a comparison clock pulse signal (VT) and a reference clock pulse signal (RT). It includes logic gates (STO,STA) for generating start and stop pulses from respective successive pulses of the comparison and reference clock pulse signals (RT,VT). A counter (ZG,Z) counts the pulses of a counter clock pulse signal (ZT) of a higher frequency in a time window between the start signal and the subsequent stop signal. The counter value of the counter is a measure of the phase shift between the comparison and reference clock pulse signals (VT,RT). Quantization errors in the phase shift signal are considerably reduced by providing a logical gate (VZ) for determining the sign of the phase shift and a device ( mu P) for adding a constant, advantageously 0.5, to the counter value. The phase detector of the invention makes possible phase control loops providing precise pulse tracking, since it makes available a regulating signal, even with the smallest phase shifts between the comparison and reference clock pulse signals.
Patent FI-963995-A0 (FI)
Inventor: HEERES JAN
IPC: C07D401/14
Filed: 1996-10-04
Abstract: PCT No. PCT/EP95/01184 Sec. 371 Date Sep. 20, 1996 Sec. 102(e) Date Sep. 20, 1996 PCT Filed Mar. 29, 1995 PCT Pub. No. WO95/27704 PCT Pub. Date Oct. 19, 1995The invention is concerned with the compounds having the formula    <IMAGE>  (I)    <IMAGE>   the pharmaceutically acceptable acid addition salts and the stereochemically isomeric form thereof, wherein X and Y are CH or N; R1, R2 and R3 are hydrogen or C1-4alkyl; R4 and R5 are hydrogen, halo, C1-4alkyl, C1-4alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R6 is C1-6alkyl, hydroxyC1-6alkyl, C1-4alkyloxyC1-6alkyl, phenyl or phenylC1-4alkyl; Z is C=O or CHOH; and IMAGE>  (a-3)   <IMAGE>  (a-4)   <IMAGE>  (a-5)   <IMAGE>  (a-6)   <IMAGE>  (a-7)  compositions comprising said compounds, processes for preparing the same and the use of these compounds for treating Helicobacter related diseases.
Patent FI-964669-A0 (FI)
Inventor: CHEN CHENG Y
IPC: C07D403/06
Filed: 1996-11-22
Abstract: A new process is described for the synthesis of the triazolyl tryptamine:   <IMAGE>   and related compounds. The process involves a palladium-catalyzed ring closure between a substituted ortho-iodoaniline and a protected 1-alkynol. The process is carded out at high temperature, e.g. 100 DEG  C., in a dry inert solvent, e.g., DMF and in the presence of a proton acceptor, e.g., Na2CO3 or a trialkylamine. The triazolyl tryptamine, as well as acid addition salts thereof, is a 5 HT1D receptor agonist having anti-migraine properties.
Patent IL-72523-A0 (IL)
Title: Condensed seven-membered ring compounds and their production and use
IPC: C07D211/34
Filed: 1984-07-27
Abstract: Novel condensed, seven-membered ring compounds of the formula 
<CHEM>
 [wherein R<1> and R<2> are independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or both jointly form tri- or tetramethylene; R<3> is hydrogen, optionally substituted lower alkyl or optionally substituted aralkyl; R<4> is hydrogen, optionally substituted alkyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl; Y is a carboxyl group which may be esterified or amidated; m is 1 or 2] and salts thereof. 
<??>These compounds and salts thereof exhibit inhibitory activity on angiotensin converting enzyme and so forth, and are of value as an agent for diagnosis, prevention and treatment of circulatory diseases (e.g. hypertension, cardiopathy, cerebral apoplexy).
Patent IL-86480-A0 (IL)
Title: Recombinant dna coding for human proapolipoprotein a-i,expression vectors containing it and cells transformed by said expression vector
IPC: C12N5/10
Filed: 1988-05-24
Abstract: The present invention provides recombinant DNA sequences comprising a sequence which codes for human proapolipoprotein A-I wherein part of the natural coding sequence has been replaced by a DNA fragment coding for the same amino acids but consisting of a different nucleotide sequence such as to reduce or prevent formation of hairpins, cloning and expression vectors containing these DNA sequences, cell cultures or microorganisms transformed with these expression vectors and processes using the same for the production of proapolipoprotein A-I.
Patent IL-93218-A0 (IL)
Title: High salt content rapid disinfection solution for contact lenses
IPC: C11D3/20
Filed: 1990-01-30
Abstract: A disinfection solution, primarily for use in conjunction with contact lenses is disclosed comprising an amount of a pharmaceutically acceptable ionic salt which is equivalent in ionic strength to at least 5 % w/v sodium chloride, at least one of a C2-6alkanol and a C3-8alkylene glycol, a pharmaceutically acceptable surfactant, optionally a buffer and a viscosity enhancing agent, and water.
Patent IL-97506-A0 (IL)
Title: Flush-mount sink assembly method
IPC: B24B9/00
Filed: 1991-03-11
Abstract: The flush-fit mounting of an accessory such as a sink or bowl in a surface of hard material such as granite or marble can be achieved by a method comprising the steps of: forming an opening in the mounting surface for seating the accessory within the perimeter of the edges of said opening; supporting, in proximity to said opening, a guide means having the contour of a mounting edge of said accessory, cutting, using cutting means movable in relation to said guide means, said edges of said opening to provide therein a bevelled edge suitable for mounting said accessory edge therein in flush-fit fashion; and adjusting said cutting means in relation to said guide means as necessary, during said cutting step, so as to maintain said cutting means sharp while maintaining uniformity of said bevelled edge over said perimeter of said opening. <IMAGE>
Patent IL-99540-A0 (IL)
Title: Sulfonamide fibrinogen receptor antagonists and pharmaceutical compositions containing them
IPC: C07D211/22
Filed: 1991-09-20
Abstract: Sulphonamido-phenylalkanoic acid derivs. of formula (I), and their salts, are new. In (I), R1 = Het1 opt. substd. NR6R7, R6R7NC- (=NR6)- R6R7NC(=NR6)NH-, R6C(=NR7)NR7- or a gp. (a) or (b); Het1 = a 4-8 member heterocyclic ring contg. 1-4 heteroatoms from N, O, S; R6, R7 = H, 0-10C alkyl or cycloalkyl, both opt. substd. Het2 = 1-4C alkanoylamino, 1-6C alkoxycarbonyl, 0-6C alkylamino; 1-10C alkylsulphonylamino, 4-10C aralkylsulphonylamino, 4-10C aralkyl, 1-10 1-10C alkaryl, 1-10C alkylthio 4-10C aralkylthio, 1-10C alkylsulphinyl, 4-10C aralkylsulphinyl, 1-10C alkylsulphonyl, 4-10C aralkylsulphonyl, aminosulphonyl, 1-10C alkylaminosulphonyl, 4-10C aralkylsulphonylamino, oxo, thio, or 1- or 2-ethenyl or 3- propenyl, all opt. substd.; "alkyl" = from alkane, alkene or alkyne; alkoxy = O-alkyl; aralkyl and alkaryl contain alkyl as defined above and aryl defined below; Het2 = a 5 or 6 membered satd. heterocyclic ring contg. 1-4 heteroatoms from N, O, S; aryl = a mono- or poly-cyclic ring system of 5- and 6-membered aromatic rings contg. 0-4 heteroatoms from N, O, S; R2, R3 = H, aryl, or 0-10C alkyl or cycloalkyl both opt. substd.; R4 = aryl, 1-10C alkyl or cycloalkyl, 4-1UC aralkyl, 1-10C alkoxyalkyl, 1-10C alkaryl, 1-10C alkylthioalkyl, 1-10C alkoxythioalkyl, 1-10C alkylamino, 4-10C aralkylamino, 1-10C alkanoylamino, 4-10C aralkanoylamino, 1-10C alkanoyl, 4-10C aralkanoyl, or 1-10C carboxyalkyl opt. substd. R5 = Het1, COR8, or CSR8; R8 = e.g. OH, 1-10C alkyloxy, 1-10C alkaryloxy, etc. X. Y, Z are opt. substits. and = NR6, O, S, SO, CO, CS CH(OH), SO2, CR6=CR7, CC, Het1, (opt. substd. at any atom with R6), aryl, CONR6, NR6CO, NR6SO2, or SO2NR6; m = 0-10; n = 0-10; and p = 0-3.
Patent AU-PR056300-A0 (AU)
Title: Edge coated ophthalmic lens
IPC: G02B1/10
Filed: 2000-09-29
Abstract: The disclosure relates to the provision of a lens having front and back optical surfaces bound by a peripheral edge, wherein the peripheral edge is coated with an edge coating that strongly bonds to the edge but that only weakly bonds to the optical surface, and wherein the edge coating is durable. A method of coating and a composition are also disclosed. The composition is preferably selected from a limited group of UV curable acrylates.
Patent AU-PR071200-A0 (AU)
Title: Safety headgear
IPC: A42B3/14
Filed: 2000-10-12
Abstract: The present specification protective headgear including a unitary shell (1) having a bell shape with a non-uniform thickness, the shell being of sufficient size to enclose at least an upper part of the wearer's skull, the shell having an upper crown portion (6) with a central crown area (2) and a surrounding outer crown area (3), the shell further including a depending circumferential wall which has an upper wall area (4) adjacent to the outer crown area (2) and a lower wall area (5), the lower wall area (5) having a wall thickness generally greater than the wall thickness of said upper wall area (4), and the central crown area (2) having a wall thickness generally greater than the wall thickness of said outer crown area (3), the headgear further including a support system (9) attached to the lower wall area(s) of the shell (1) in a manner whereby no less than 5 mm space is maintained between the wearer's skull and an inside surface of the shell (1).
Patent FI-20021069-A0 (FI)
Inventor: PAEAERNI HANNU
IPC: H04R31/00
Filed: 2002-06-04
Abstract: This publication discloses an acoustically active element formed in a multi-layer circuit-board structure ( 20, 22, 24, 25 ), a method for manufacturing it, and a multi-layer circuit-board structure. The acoustically active element includes an internal chamber ( 21 ) and a membrane ( 18 ) or beam arranged in connection with the internal chamber ( 21 ), which acts as a vibrating element and is connected electrically to external circuits, in order to produce or measure an acoustic effect. According to the invention, the resonance chamber ( 21 ) is formed inside the multi-layer circuit-board structure ( 20, 22, 24, 25 ), in connection with the process of manufacturing the circuit board.
Patent IL-104403-A0 (IL)
Title: Spirally wound tampon with overwrap
IPC: A61F13/20
Filed: 1993-01-15
Abstract: A tampon is provided which includes an absorbent material (12) wound in a spiral configuration, the outermost winding (18) of the spiral having a liquid permeable overwrap material (10) disposed thereon, a portion of said overwrap being folded over the edge (18) of the spiral which corresponds to the withdrawal end of the tampon and adhered (seal 16) to the inside surface (13) of said outermost winding. <IMAGE>
Patent IL-110069-A0 (IL)
Title: Isolated dna sequence which can serve as terminator region in a chimeric gene capable of being used for the transformation of plants
IPC: A01H5/00
Filed: 1994-06-20
Abstract: 1) Chimeric gene for plant transformation. 2) It comprises at least, in the direction of transcription, a promoter region, a transgene and a termination region, characterised in that the termination region consists of at least one termination region of a plant histone gene which permits the expression of the protein in the regions of rapid growth. 3) Production of transgenic plants.
Patent IL-116122-A0 (IL)
Title: Intermediates to heterocyclic-cyclic amine derivatives
Inventor: VILLALOBOS ANABELLA
IPC: A61K31/495
Filed: 1992-03-22
Abstract: Compounds of formula (I) wherein R<1>, R<2>, R<7>, R<8>, X, Y, M and L are defined as below. The compounds of formula (I) are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.
Patent IL-119627-A0 (IL)
Title: Controlled-release pharmaceutical preparations
IPC: A61K31/43
Filed: 1996-11-17
Abstract: The present invention relates to a pharmaceutical controlled-release oral drug delivery system comprising as active ingredient at least one beta-lactam antibiotic agent, having a specific absorption site in the small intestine in combination with a polymeric matrix, optionally further containing additional pharmaceutically acceptable constituents, wherein at least 50% of the beta-lactam antibiotic agent are released from the matrix within from about 3 to about 4 hours from oral administration and the reminder of the pharmaceutical agent is released at a controlled rate. The drug delivery system according to the invention optionally further comprises a beta-lactamase inhibitor, preferably in combination with amoxicillin and/or amoxicillin trihydrate as the active ingredient. The polymeric matrix of the pharmaceutical controlled-release oral drug delivery system of the invention my be of hydrophilic and/or hydrophobic nature and the delivery system may further comprise pharmaceutically acceptable additive. The pharmaceutical controlled-release oral drug delivery system of the invention is preferably in dosage unit form.
Patent IL-121541-A0 (IL)
Title: Oxazoline derivatives and processes for the preparation of same
IPC: C07D417/04
Filed: 1997-08-13
Abstract: Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain-bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided.
Patent IL-132703-A0 (IL)
Title: Method and apparatus for monitoring the progress of labor
IPC: A61B8/02
Filed: 1998-05-04
Abstract: A method of monitoring the progress of labor in a mother during childbirth, by attaching a position sensor to a predetermined point on the mother's pelvic bones; monitoring the location of the position sensor in three- dimensional space relative to a reference; and monitoring the location of the fetal presenting part with respect to the predetermined point on the mother's pelvic bones. The location of the fetal presenting part may be indicated by a similar position sensor, or by imaging. Other conditions, such as effacement, cervical dilatation, and cervical position may also be monitored in a similar manner.
Patent IL-134373-A0 (IL)
Title: Macrolides with antitumor activity
IPC: C07D493/20
Filed: 1998-08-04
Abstract: The compound referred to herein as IB-962 12, having structure (I) can be obtained by cultivating the strain of Micromonospora sp. ES25-008, available under the accession number CECT-3333, and can be hydrolyzed to give IB-96212B having structure (II). The sugar substituent which is L-rhodinose, can its elf be derivatized or the sugar can be replaced, in either case, giving further derivatives of IB-96212 having a group other than L-rhodinose at the position of the sugar.
Patent IL-137406-A0 (IL)
Title: Universal signal distribution system
IPC: H04H20/78
Filed: 1999-01-18
Abstract: The present industrial invention concerns a system for the distribution in a condominium and/or community environment of a plurality of television signals, and/or audio signals, and/or digital audio and/or video signals transmitted with different standards. According to the invention, one or more digital signals can be received by a single user of the system by means of a frequency conversion into a predetermined channel, which can be accessed by said user only. Moreover, the digital signal being present in said channel always has the same modulation and can be selected by said user through control means which send a control signal to selection means.
Patent IL-139611-A0 (IL)
Title: Presence detector and its application
IPC: G08B13/196
Filed: 2000-11-10
Abstract: A presence detector has a passive infrared sensor (2) that activates a CMOS (Complementary Metal Oxide Silicon) visible light active pixel imaging sensor (1) with combined or separate ambient light measurement (4) and a combined sensor signal processor (3) with separate imaging of part images to control room lighting (5), air conditioning, ventilation and heating (6).
Patent IL-141201-A0 (IL)
Title: Valve assembly
IPC: F16K31/08
Filed: 1999-10-01
Abstract: A valve assembly includes a valve body and, located therein, a valve member which can be moved between a first position, in which the valve is in a first operational mode, and a second position, in which the valve is in a second operational mode. The valve member has a rare earth magnet which, when the valve member is in either one of the two operational modes, causes the valve member to be magnetically biased against movement toward the other operational mode. The valve is provided with a device for generating a magnetic field sufficient for overcoming the magnetic bias in the first or second operational mode, so as to cause the valve member to move to the other of the operational modes.