baber/WOPTO huggingface dataset:
Patent CY-1111648-T1 (CY)
Title: Πολυαρυλκαρβοξαμιδια χρησιμα ως παραγοντες μειωσης λιπιδιων
Inventor: MEERPOEL LIEVEN
IPC: C07D295/14
Filed: 2011-01-19
Abstract: Ενώσεις πολυαρυλκαρβοξαμιδίων του τύπου (Ι) είναι χρήσιμες ως παράγοντες μείωσης λιπιδίων.
Patent CY-1111693-T1 (CY)
Inventor: WATSON KEITH
IPC: C07D277/68
Filed: 2011-07-06
Abstract: This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals as well as novel intermediates useful in the preparation of the compounds of formula I.
Patent CY-1117355-T1 (CY)
Title: Μονοκλωνικα αντισωματα αντi-φερροπορτiνης 1 και χρησεις αυτων
Inventor: LEUNG DONMIENNE DOEN MUN
IPC: C07K16/28
Filed: 2016-04-12
Abstract: Παρέχονται μονοκλωνικά αντισώματα και θραύσματα αυτών που δεσμεύονται με αντιγόνο τα οποία δεσμεύονται με ανθρώπινη FPN1 και αναστέλλουν την δραστικότητα της, και τα οποία είναι αποτελεσματικά σε διατήρηση ή αύξηση της μεταφοράς σιδήρου εκτός κυττάρων θηλαστικού και/ή σε διατήρηση ή αύξηση του επιπέδου σιδήρου ορού, αριθμού δικτυοκυττάρων, αριθμού ερυθρών αιμοσφαιρίων, αιμοσφαιρίνης, και/ή αιματοκρίτη σε υποκείμενο in vivo.
Patent CY-1118370-T1 (CY)
Title: 4-(8-μεθοξυ-1-((1-μεθοξυπροπαν-2-υλ)-2(τετραϋδρο-2η-πυραν-4-υλ)-1η-ιμιδαζο[4,5-c]κινολιν-7-υλ)-3,5-διμεθυλισοξαζολιο και χρηση αυτου ως αναστολεας βρωμοπεδιο
Inventor: DEMONT EMMANUEL HUBERT
IPC: A61K31/4745
Filed: 2016-12-16
Abstract: Νέες ενώσεις κινολίνης του τύπου (I), φαρμακευτικές συνθέσεις που περιέχουν τέτοιες ενώσεις και χρήση αυτών στη θεραπεία, ως αναστολείς βρωμοπεδίου.
Patent CY-1120670-T1 (CY)
Title: Μονοκλωνικα αντισωματα εναντι του αναστολεα μονοπατιου ιστικου παραγοντα (tfpi)
Inventor: WANG ZHUOZHI
IPC: C12P21/08
Filed: 2018-07-11
Abstract: Παρέχονται απομονωμένα μονοκλωνικά αντισώματα που δεσμεύουν τον ανθρώπινο αναστολέα του μονοπατιού ιστικού παράγοντα (tissue factor pathway inhibitor, ΤFΡΙ) καθώς και τα απομονωμένα μόρια νουκλεϊνικού οξέος που κωδικοποιούν τα ως άνω αντισώματα. Παρέχονται επίσης φαρμακευτικές συνθέσεις που περιέχουν τα μονοκλωνικά αντισώματα αντι-ΤFΡΙ και μέθοδοι για τη θεραπευτική αντιμετώπιση ελλειμμάτων ή ελαττωμάτων στην πήξη με χορήγηση των αντισωμάτων. Παρέχονται επίσης και μέθοδοι για την παραγωγή των αντισωμάτων.
Patent CY-1122412-T1 (CY)
Title: Ομοιοπολικα διασωματα καi χρησεις αυτων
Inventor: JOHNSON LESLIE S
IPC: C07K16/28
Filed: 2019-04-30
Abstract: Η παρούσα εφεύρεση αφορά σε μόρια διασωμάτων και χρήσεις αυτών για τη θεραπευτική αντιμετώπιση ποικίλων νόσων και διαταραχών, συμπεριλαμβανομένων των ανοσολογικών διαταραχών, των μολυσματικών νόσων, της τοξίκωσης και του καρκίνου. Τα μόρια διασωμάτων της εφεύρεσης περιλαμβάνουν δύο πολυπεπτιδικές αλύσους που σχετίζονται μεταξύ τους, ώστε να σχηματίσουν τουλάχιστον δύο θέσεις δέσμευσης επίτοπων, που δύνανται να αναγνωρίζουν τον ίδιο ή διαφορετικούς επίτοπους στα ίδια ή σε διαφορετικά αντιγόνα. Επιπροσθέτως, τα αντιγόνα δύνανται να προέρχονται από τα ίδια ή από διαφορετικά μόρια. Οι μεμονωμένες πολυπεπτιδικές άλυσοι του μορίου του διασώματος δύνανται να δεσμεύονται ομοιοπολικώς μέσω ομοιοπολικών δεσμών μη πεπτιδικού δεσμού, όπως είναι ενδεικτικά η δισουλφιδική δέσμευση των υπολειμμάτων κυστέίνης που ευρίσκονται εντός κάθε πολυπεπτιδικής αλύσου. Σε συγκεκριμένες υλοποιήσεις, τα μόρια διασωμάτων της παρούσας εφεύρεσης περιλαμβάνουν περαιτέρω μία περιοχή Fc, η οποία επιτρέπει την ομοιάζουσα με αντίσωμα λειτουργικότητα να κατασκευαστεί εντός του μορίου.
Patent CY-1123529-T1 (CY)
Title: Ανακυκλωση οικιακων αποβλητων υλικων
Inventor: HALL PHILIP
IPC: B09B3/00
Filed: 2020-06-09
Abstract: Μια διεργασία και μια συσκευή ανακύκλωσης αστικών οικιακών αποβλήτων περιλαμβάνει την υποβολή του απόβλητου σε υδρατμό (12) στους 150 °C - 200 °C σε πίεση πάνω από την ατμοσφαιρική η οποία όμως θα είναι λιγότερο από το διπλάσιο της ατμοσφαιρικής πίεσης. Μετά από την κατεργασία με υδρατμό, το υλικό που προκύπτει διαχωρίζεται (Ε) σε συστατικά μέρη και η βιομάζα και/ή τα πλαστικά υποβάλλονται σε περαιτέρω κατεργασία (G, Η). Κατά προτίμηση η περαιτέρω κατεργασία παράγει βιοαιθανόλη από τη βιομάζα και ντίζελ από τα πλαστικά. Ως εναλλακτική λύση, ένα μέρος ή ολόκληρη η βιομάζα ενδέχεται να αεριοποιηθεί με σκοπό την παραγωγή υδρογόνου, το οποίο ενδέχεται με τη σειρά του να τροφοδοτηθεί σε μια κυψέλη καυσίμου για να παραχθεί ηλεκτρική ισχύς.
Patent GR-940300057-T1 (GR)
Title: Deodorisation device, by catalytic destruction of organic compounds in air to be purified.
Inventor: AUVRAY PHILIPPE
IPC: B01D53/86
Filed: 1994-08-31
Abstract: The invention relates to a device for purifying air, in particular by deodorizing, by catalytic breakdown of the organic species present in the air to be purified, including:   - a tubular element (1) containing an air-permeable block (3) which is interposed in the air stream inside the tubular element,   - means (82) for heating this block, and - fan means (5) for causing a forced flow of the air in the tube and through the block.   <IMAGE>
Patent HR-P20090323-T1 (HR)
Title: Cooking vessel with handle
Inventor: BECK HANS-JUERGEN
IPC: A47J45/08
Filed: 2009-06-02
Abstract: A cooking vessel has a handle, in particular for a pot or a pan, wherein the grip region of said handle is composed of metal. In this case, the handle has at least one first substantially metal fixing section for being fixed to the cooking vessel, a transition section and a substantially metal grip section. The transition section has a reduced metal cross section compared to the adjacent sections, wherein said transition section respectively comprises either a metal section, which is integrally connected to the adjacent sections, and a ceramic piece, or comprises only a ceramic piece, and the ceramic pieces are connected to the adjacent adjoining metal sections in an interlocking manner. The result of this is a reduction in thermal conductivity in the grip region without reducing the stability of the handle.
Patent SI-1462442-T1 (SI)
Title: Crystals of bicalutamide and process for their production
Inventor: SHINTAKU TETSUYA
IPC: A61K31/00
Filed: 2002-12-13
Abstract: The present invention relates to a crystal of bicalutamide having a defined form, as well as economical and industrially practical production methods of bicalutamide and a crystal thereof, which are superior in environmental benignity and safety. <??>Accordingly, the present invention provides a production method of bicalutamide represented by the formula (I): <CHEM> which includes at least a step of reacting a compound represented by the formula (3): <CHEM> with an oxidizing agent, a production method of a crystal of bicalutamide, as well as a crystal form of bicalutamide as defined by X-ray diffraction (XRD) or solid <13>C NMR measurement. <IMAGE>
Patent SI-1749524-T1 (SI)
Title: Inflammation-inhibiting compounds
Inventor: LUGER DR THOMAS
IPC: A23L33/18
Filed: 2002-02-08
Abstract: Use of lysine derivatives (I), or their acceptable salts for treatment and/or prevention of inflammatory diseases. Use of lysine derivatives of formula (I), or their acceptable salts, for treatment and/or prevention of inflammatory diseases. X : hydroxy, amino, alkoxy, Pro or Pro-Thr (I) may be N-acylated and/or C-amidated or -esterified. An independent claim is also included for in vitro preparation of cells that can impart tolerance to an antigen (Ag) by treating antigen-presenting cells (APC) with alpha-melanocyte stimulating hormone (aMSH), or its biologically active fragments or derivatives, and with Ag, in either order or simultaneously. [Image] ACTIVITY : Antiinflammatory; Antiallergic; Immunosuppressive; Antifibrotic; Dermatological; Antipsoriatic; Antiasthmatic; Antiulcer. Mice were sensitized to the hapten DNFB, then (after 7 days) the same hapten was applied to the ear, and after a further 24 hr the swelling of the ear was measured. The mean value was 7 (mmX10 -2>), but only 1 when the mice had been injected, intraperitoneally, with an unspecified dose of Lys-Pro-Thr, 2 hr before sensitization. The treated animals did not respond to a second sensitization/challenge, showing that tolerance had been induced. MECHANISM OF ACTION : (I) inhibits activation of the NF-kappaB transcription factor by cytokines or lipopolysaccharide; Reduces expression of costimulatory molecules from dendritic cells and increases production of interleukin-10 from monocytes. (I) may bind to the beta -adrenergic and type 1 interleukin-1 receptors, possibly also to other receptors.
Patent SI-1380531-T1 (SI)
Title: Elevator landing door
Inventor: BORNECK ROLF
IPC: B66B13/30
Filed: 2003-05-14
Abstract: The sliding door at an elevator shaft has two panels (2,3) suspended from upper running trolleys (4,5) to ride in lower guides. On the opening/closing movements, the panels slide in the same direction but on paths of different lengths in an overlapping action. The running trolley (4) for the panel with an accelerated movement on a closing action is at the end of a fixed draw cable (8), which is around deflection rollers (9,10) fitted to the trailing panel. The deflection rollers are of different diameters, and rotate around vertical axes (11,11'). The ends of the cable are offset in parallel, secured to the trailing end of the running trolley in the closing direction so that, on a closing movement, the shorter end of the cable is around the deflection roller (10) with the smaller diameter.
Patent SI-1479363-T1 (SI)
Title: Application of cosmetics in the skin
Inventor: MILLET OSWALD
IPC: A61F13/00
Filed: 2003-09-25
Abstract: The method for active introduction of moisturizing and/or cosmetic substances into the skin of a human being consists of bringing the skin in contact with such substances, applying compression bandages, and setting the tissues joined to the skin in vibration. Independent claims are also included for (a) an application of a compression bandage for implementation of the proposed method (b) a compression bandage with an outer, substantially liquid-tight cover (c) an apparatus for implementation of the proposed method.
Patent SI-1711518-T1 (SI)
Title: Chimpanzee adenovirus vaccine carriers
Inventor: CIRILLO AGOSTINO
IPC: C12N15/00
Filed: 2005-01-18
Abstract: The present invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses and methods for generating recombinant adenoviruses in human E1-expressing cell lines. The invention also provides compositions and methods suitable for use for the delivery and expression of transgenes encoding immunogens against which a boosted immune response is desired. The invention further provides methods of generating clinical grade vector stocks suitable for use in humans. In a particular embodiment the invention contemplates the use of vectors comprising transgenes which encode tumor associated antigens in vaccines and pharmaceutical compositions for the prevention and treatment of cancer.
Patent SI-1826153-T1 (SI)
Title: Container way
Inventor: GRILLI SILVIO
IPC: B61B13/00
Filed: 2006-01-30
Abstract: The method involves building a transport system over a long distance and driving the containers on rotating drive units so that remote delivery of the containers is possible over a regional scale. The containers can be moved by guide rollers fixed on the transport system. Independent claim describes transport system with elongated frame, several rotatable drive units fixed parallel to one another crosswise on the frame and each having a drive wheel for the container wherein remote delivery of the containers is possible over a regional scale. A maintenance track can be provided centrally between two or four tracks.
Patent SI-2019782-T1 (SI)
Title: Packaging machine using heat sealable film
Inventor: SAMBUGARO ALESSANDRA
IPC: B65B9/00
Filed: 2007-05-18
Abstract: The invention is a packaging machine using heat sealable film, of the type suitable for packaging the product (P) with a heat sealable film or net (S), through the use of heat sealing rollers that make the longitudinal edge of the wrap, of cut-and-sew blades that make the two transverse edges of said wrap and of a forming tunnel that shapes said film unwound from a reel. This machine is characterized in that the above-mentioned devices and their operating accessories are all applied to and supported by a single structure, in such a way as to form a working unit in a single piece which is connected with the pin to a support, integral with a fixed base and capable of rotating angularly on a vertical plane.
Patent SI-2585622-T1 (SI)
Title: Arc deposition source having a defined electric field
Inventor: KRASSNITZER SIEGFRIED
IPC: C23C14/00
Filed: 2011-06-03
Abstract: The invention relates to an arc deposition device, comprising a cathode, an anode, as well as a voltage source for putting the anode at positive potential relative to the cathode. The device also comprises magnetic elements, which cause a magnetic field over the cathode surface, wherein the anode is arranged in the vicinity of the cathode in such a way that the magnetic field lines exiting from the cathode surface hit the anode.
Patent DE-3687058-T2 (DE)
Inventor: RESNICK BRUCE M
IPC: G03C1/06
Filed: 1986-09-26
Granted: 1993-03-25
Abstract: Disclosed are novel compounds of the formula: wherein:X=-NR₅R₆, or -OR₇;R₁ and R₂ are independently hydrogen, substituted or unsubstituted alkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, alkylaminoalkyl or arylalkyl having up to 18 carbons; cyclo­alkyl; phenyl or naphthyl; alkylphenyl, cyanophenyl, halophenyl or alkoxyphenyl substituents.R₃ is hydrogen, benzyl, alkoxybenzyl, halobenzyl or alkylbenzyl, provided that if neither R₁ nor R₂ is hydrogen, then R₃ is hydrogen.R₄ is a divalent aromatic group which is substitu­ted or unsubstituted.R₅, R₆, and R₇ are independently hydrogen, alkyl, hydroxyalkyl, haloalkyl, alkoxyalkyl, alkylaminoalkyl, acyl­aminoalkyl, aminoalkyl or phenylalkyl having up to 12 carbons; a cycloalkyl substituent; phenyl or naphthyl; an alkylphenyl, cyanophenyl, halophenyl or alkoxyphenyl substituent.Furthermore, either R₁ and R₃ or R₁ and R₂ can be linked to form a heterocyclic ring system containing 3-10 atoms.Additionally, R₅ and R₆ can be linked to form a heterocyclic ring system containing 3-10 atoms.Y is an oxygen or sulfur atom. If Y is sulfur then n=1, if Y is oxygen then n=0 or 1. These compounds are useful as high-quality dot promoting agents in negative-working photographic systems.Disclosed as well are radiation-sensitive compositions and elements containing such dot promoting agents in combination with silver halide grains. These exposed compositions and elements when processed in a developer containing a dihydroxybenzene developing agent, a substituted benzotriazole, a sulfite preservative and an amine compound provide a method for the production of halftone dots possessing high image quality.
Patent DE-3781491-T2 (DE)
Inventor: STERMAN SAUL
IPC: G02C7/02
Filed: 1987-09-15
Granted: 1993-03-04
Abstract: A method of tinting soft contact lenses (L) uses at least one transfer-pad printer (2) including a suitable ink of the desired tint, and at least one printing block (6) carrying an iris pattern. The contact lenses are attached to lens mounts (14), preferably by being shrunk onto curved heads (18) of the mounts, and are then aligned, in turn, with the pad (4) of the transfer-pad printer (2). For each lens, the printing block (6) is inked, the pad is caused to pick up the iris pattern from the inked block, and the pad is then caused to make contact with the mounted lens, thereby transferring the iris pattern as picked up from the block to the mounted contact lens. Apparatus for carrying out the method is also described.
Patent DE-3786688-T2 (DE)
Inventor: BROWN III FRED ALBERT C O COMA
IPC: H02H7/085
Filed: 1987-01-16
Granted: 1993-11-11
Abstract: A brushless DC fan (10) with a winding supply circuit (49) having an internal voltage regulator (53) can afford current limiting and thermal protection and provide various desired fan speeds without alteration of the basic fan circuit, the windings, or other manufacturing items. A voltage setting circuit element (63) can set fan speed externally and can be used to establish various fan speeds. An internal voltage establishing circuit element (58) sets the maximum speed. The regulator replaces the fan's protective thermistor to shut down the voltage to the windings (47) when locked rotor occurs. Bringing out a lead (21) for the purpose of connecting a speed controlling resistor, thermistor, or active programming means to the internal circuitry enables the fan's end user to alter operation as needed.
Patent DE-3881051-T2 (DE)
Inventor: LINDMARK GUNNAR
IPC: F16K17/34
Filed: 1988-03-10
Granted: 1993-12-23
Abstract: A pressure drop hose valve comprises a valve body (1) having an inlet (4) and an outlet (5) as well as a throughflow passageway (6) which connects the inlet and the outlet and in which a valve cone (7) is axially movable. The portion of the valve cone (7) facing the outlet (5) is formed with a seat surface (10) for cooperation with a seat (9) provided in the passage of the valve body and normally located at a distance from said valve cone seat surface (10). A spring (13) strives to displace the valve cone (7) towards the inlet (4), the seat surface of the valve cone and the valve seat of the body being designed such that the valve cone, during its displacement towards the outlet (5) after activation of the valve following a pressure drop in the hose, is constantly held or wedged in the seat.
Patent DE-3884888-T2 (DE)
Inventor: MORINAGA AKIO
IPC: C08L23/16
Filed: 1988-08-12
Granted: 1994-04-28
Abstract: A dispersion of fine particles of an ethylene polymer or ethylene polymer composition dispersed in a hydrocarbon solvent, wherein the ethylene polymer or ethylene polymer composition has an acid value of 0.3 to 75 mg-KOH/g as a whole and a crystallinity of at least 45% as determined by the X-ray diffractometry and has an average dispersed particle size of 0.3 to 20 um and a concentration of 15 to 60% by weight may be used as an additive to oily printing inks.
Patent DE-3887686-T2 (DE)
Inventor: NIKITENKO VYACHESLAV IVANOVICH
IPC: C12R1/125
Filed: 1988-11-04
Granted: 1994-08-18
Abstract: A bacterial preparation for the prophylaxis and treatment of inflammatory processes and allergic diseases consists of the cells of at least one microorganism capable of penetrating from the gastroenteric tract to the lesion focus, maintaining its own viability and producing antibiotics, proteolytic ferments, immunomodulators, and comprises from 5 to 1x10<9> of living cells of the microorganism in 1 mg of the preparation.
Patent TR-199801127-T2 (TR)
Inventor: HAAS CHARLES LEE
IPC: C07D231/44
Filed: 1996-12-19
Abstract: Bu bulus X'in klor veya brom oldugu; Y'nin trifluorometil veya trifluorometoksi ve R1'in hidrojen, metil veya etil oldugu ve açik formüllü (I)'de gösterilen 1-arilpirazol'ler ve bunlarin pestisit olarak kullanimi ile ilgilidir.
Patent TR-199901038-T2 (TR)
Inventor: PETRI MARCO
IPC: C11D3/39
Filed: 1997-11-06
Abstract: Bu bulus, 8'in yukarisinda bir pH degerine sahip olan ve bir peroksijen agartici, kök temizleyici madde, kenetleme maddesi ve pH tamponu içeren, dengeli, sivi, sulu bilesimlere iliskindir.
Patent DE-60000073-T2 (DE)
Inventor: MEKOUAR KHALID
IPC: C07D491/22
Filed: 2000-05-25
Granted: 2002-08-01
Abstract: The invention concerns the preparation of nothapodytine or camptothecin derivatives which consists in causing 4-ethyl 2methyl hepta-2,4-dienoic acid act on a 3-aminomethyl 2-bromo quinoline derivative (III) wherein R1 and R2 are H or R1 is a halogen atom or alkyl, R2 is a O-CO-X radical as defined for the camptothecin derivatives; or R1 and R2 are defined for the known camptothecin derivatives or represent protected radicals or radicals easily convertible into the radicals R1 and R2, to obtain the quinoline derivative (IV); adding to the resulting quinoline derivative (2-methoxy carbonyl vinyl) tributyltin in the presence of a complex of palladium and triphenylarsin to obtain the quinoline derivative (V); cyclizing the resulting quinoline derivative to obtain the tetracyclic derivative (VI); then in subjecting said derivative to an ozonolysis followed by treatment with dimethyl sulphide to obtain the tetracyclic derivative (VII); saponification followed by decarboxylation in oxidising conditions of the resulting tetracyclic derivative to obtain the nothopodytine derivative (VIII); then optionally transforming the resulting derivative into a camptothecin derivative or into a mappicine derivative.
Patent DE-60001433-T2 (DE)
Inventor: BERG-SCHULTZ KATJA
IPC: C07C45/00
Filed: 2000-03-20
Granted: 2003-10-30
Abstract: The present invention relates to new alpha,beta-unsaturated ketones of formula I. The new compounds exhibit an intense, very long lasting green galbanum-type odor with fruity undertones. Compositions containing these novel compounds are also provided.
Patent DE-60001509-T2 (DE)
Inventor: KAPAAN JAN
IPC: B60W30/18
Filed: 2000-08-25
Granted: 2003-09-04
Abstract: A continuously variable transmission system comprises a continuously variable transmission having two pulley sets each with two discs defining a V-shaped groove, drive means-for varying the width of said groove and a belt extending between said-pulley sets in the grooves thereof, as well as a forward-reverse control connected to the shaft of one of the pulley sets and a clutch connected to said forward-reverse control, said pulley sets, forward-reverse control and clutch each being provided with a respective actuator. The actuators of the forward-reverse control and of the clutch are of an electromechanical type.
Patent DE-60002015-T2 (DE)
Inventor: HAMILTON JOHN V
IPC: A61L27/16
Filed: 2000-07-28
Granted: 2003-11-27
Abstract: Wear resistance and oxidation resistance of polymer material or a polymer component for bioimplantation are improved by packaging a polymer object in a sealed gas impermeable package substantially free of oxygen, irradiating the package with penetrating radiation to an extent sufficient to effect a desired substantial level of cross-linking within the polymer, and warming the packaged object while maintaining an elevated hydrostatic pressure to cause gases released during irradiation to recombine, stabilizing the material against subsequent oxidative change. The pressure stabilization terminates active sites, substantially eliminating free radicals. When applied to finished parts, the process simultaneously hardens and sterilizes the parts without degrading mechanical properties or dimensions. When applied to bulk material or unfinished parts, the part may be subsequent machined or otherwise finished, and sterilized by any conventional means. The procedure achieves high levels of cross linking without increasing susceptibility to aging or chemical degradation.  <IMAGE>
Patent DE-60012710-T2 (DE)
Inventor: JOHNSON MARTIN STANLEY
IPC: B67D1/14
Filed: 2000-03-17
Granted: 2005-01-13
Abstract: The present invention is a flow rate control valve through which a liquid flows and from which the liquid is dispensed. The flow rate of the liquid is sensed and that information is sent to a microprocessor based control. The control operates a drive of the control valve so as to vary the resultant rate at which the liquid is dispensed therefrom. The drive operates a piston closure member that extends closely within a cylindrical passageway. The passageway has an inlet end and an outlet end and the drive operates the closure member in the passageway to a plurality of positions from a first position at the inlet end and a second position at the outlet end. The wall of the passageway defines at least one groove having a transverse cross-section that increases in area in a downstream direction from the passageway inlet to the passageway outlet or in an upstream direction from the passageway outlet to the passageway inlet, whereby movement of the closure between the first position and the second position varies the flow rate of the liquid through the control valve as a function of the cross-sectional area of the groove.