baber/WOPTO huggingface dataset:
Patent NZ-533964-A (NZ)
Title: Amidoacetonitrile derivatives
Inventor: DUCRAY PIERRE
IPC: A61P33/10
Filed: 2003-01-20
Abstract: Disclosed are compounds of formula I, wherein: R1 is H, alkyl, halo-alkyl, cyano-alkyl, alkoxymethyl or benzyl, R2, R3, R4, R5 and R6 are independently H, halo, optionally halogenated alkyl, alkenyl, alkynyl; optionally substituted alkoxy, halo-alkoxy, or cycloalkyl, or R2 and R3 are together alkylene, R7 is an optionally substituted cycloalkoxy, cycloalkylthio, or cycloalkylR9N, Ar is an optionally substituted phenyl, hetaryl, naphthyl, or quinolyl, W is O, S, S(O2) or N(R11), and the remaining substituents are defined herein. The compounds are used in the manufacture of compositions for controlling parasites in warm-blooded animals
Patent NZ-537431-A (NZ)
Title: Tyre placement apparatus
Inventor: GUNSON ROBERT JAMES
Filed: 2004-12-24
Abstract: A tyre placement and filling apparatus (10) includes a receptacle for loose material 11. Movable legs (41) are adapted so that they couple to opposing sidewalls of a tyre. There is a movable leg assembly (12) which moves the legs to expand a tyre engaged therewith, and a forcing unit (13) is operable to cause the loose material from the materials hopper (11) to transferred to, and be compacted within the tyre.
Patent NZ-538534-A (NZ)
Title: Aza-bicycloalkyl ethers and their use as alpha 7-nAChR agonist
Inventor: FEUERBACH DOMINIK
IPC: A61P25/24
Filed: 2003-09-03
Abstract: 1-aza-bicycloalkyl derivatives of formula (I) which are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists are disclosed, wherein X is CH2 or a single bond; Y is a group of formula (II, III, IV); and R is a substituted or unsubstituted C5-C10aryl or substituted or unsubstituted hetero- C5-C10aryl, N(R1)(R4), or N(R2)(CHR3R4); each of R1, R2 and R3 is independently H, C1-C4alkyl, or CF3 ; and R4 is a substituted or unsubstituted C5-C10aryl or substituted or unsubstituted hetero-C5-C10aryl. Processes for the production of these aza-bicycloalkyl derivatives, their use as pharmaceuticals and pharmaceutical compositions comprising them are also disclosed.
Patent NZ-542574-A (NZ)
Title: Use of a mixture of diacid and diamine regulated polyamide and/or copolyamide in a laser sintering layer-by-layer process for producing a three dimensional article
Inventor: MONSHEIMER SYLVIA
IPC: C08L/
Filed: 2005-09-23
Abstract: Powder, for use in layerwise processing method, with which the selective areas of the respective powdered layer are melted and solidified after cooling is disclosed, which comprises a mixture of diacid- and diamine regulated polyamide and/or copolyamide. Also disclosed is a layerwise processing method, with which selectively ranges of the respective powdered layer are melted and solidified after cooling, comprising using a mixture of diacid- and diamine regulated polyamide and/or copolyamide; and a molded article, manufactured in layerwise processing method comprising a mixture of diacid- and diamine regulated polyamide or copolyamide.
Patent NZ-544341-A (NZ)
Title: Biologically active peptide comprising tyrosyl-seryl-valine (YSV)
Inventor: WONG WAI MING
IPC: C07K5/08
Filed: 2004-06-22
Abstract: Disclosed is the tripeptide Tyrosyl-seryl-valine with its use as a pharmaceutical composition. A method is also disclosed for making a pharmaceutical composition comprising providing the tripeptide Tyrosyl-seryl-valine and mixing said tripeptide with a pharmaceutical acceptable carrier.
Patent NZ-545375-A (NZ)
Title: New therapeutic use of chondroitin sulphate
Inventor: VERGES MILANO JOSEP
IPC: A61K31/737
Filed: 2004-07-16
Abstract: Disclosed is the use of an alkaline or alkaline earth metal chondroitin sulfate, which comes from an enzymatic hydrolysis of animal cartilage, for the preparation of a medicament for the treatment or prevention of psoriasis with skin affection in a mammal.
Patent NZ-549767-A (NZ)
Title: Method for erecting a tower using a self-leveling fluid grouting material
Inventor: WOBBEN ALOYS
IPC: E02D27/42
Filed: 2005-04-04
Abstract: A method of erecting a pylon whose foundation uses a self levelling grout. It is particularly useful for a pylon of a wind power installation, which has a foundation with segment anchors, wherein connecting elements project beyond a top side of the foundation by a predetermined amount. The method has the steps of constructing an annular formwork of pre-determined width and height on the top side of the foundation (11) and filling the formwork with a fluid grouting material (16), which levels itself. When set, the grouting material (16) has an exactly levelled surface which is automatically available for use after removal of the formwork. A levelling ring (18) is placed on surface of the set grouting material (16) and the lower pylon segment (20) attached to it.
Patent NZ-554876-A (NZ)
Title: A lightweight concrete building material formulation including carboxylated butadiene styrene latex
Inventor: KEDACIC DOUGLAS
IPC: C04B14/38
Filed: 2005-10-07
Abstract: A lightweight concrete building material is disclosed. The material is formulated from a slurry prepared by mixing 6 kg of cement, 1 kg of sand, 3 litres of water and 1 litre of resin in a 20 litre bucket to form a runny paste. 54 litres of polystyrene beads and 50 ml of fibre are combined to form an even mix. The slurry is added to the even mix and mixed so that the building material has an even coating of slurry to form a cementitious mixture. The cementitious mixture is poured into a mould and allowed to set over a period of 24 hours to form a solid, and allow the solid a further period of time to air dry. The resin includes carboxylated butadiene styrene latex.
Patent NZ-556143-A (NZ)
Title: Regulation of metalloprotease cleavage of cell surface proteins
Inventor: LACKMANN MARTIN
IPC: A61K35/00
Filed: 2005-12-19
Abstract: Provided is a modified mammalian ADAM10 or ADAMl7 protease, or functional fragment thereof, having one or more non-conservative substitutions of amino acids of a substrate recognition site, thereby having a modified ability to recognize, bind and/or proteolytically cleave a substrate protein compared to a wild-type ADAM 10 or ADAM 17 protease, wherein the substrate recognition site comprises residues 573 - 579 ofADAM10 or residues 583 - 590 of ADAMI7. Further provided are corresponding nucleic acid sequences, antibodies binding the substrate recognition sites, and use of the modulators of the substrate recognition sited in the manufacture of medicaments.
Patent NZ-565032-A (NZ)
Title: An integrated mop system with pivot on sleeve on shaft to move mop head
Inventor: BERTI ENZO
Filed: 2008-01-11
Abstract: The present disclosure relates to an integrated mop system. In an embodiment, a mop includes a mop head and a shaft attached to the mop head. A handle is attached to the shaft by a pivot. An actuator member is coupled to the handle between a grip end and the pivot. Translation of the handle causes the actuator member to translate. In an embodiment, the pivot is offset from the shaft and arranged so that the shaft is located between the position where the handle is attached to the actuator member and the position where the handle is attached to the pivot. A stop may be provided to limit the translation of the handle. The actuator member is coupled a mop fiber base that supports mop fibers. The surface of the mop fibers may have a plurality of raised portions.
Patent NZ-565110-A (NZ)
Title: Compounds for the treatment of multi-drug resistant bacterial infections
Inventor: BREAULT GLORIA
IPC: C07D401/06
Filed: 2006-06-16
Abstract: Disclosed is a piperidine derivative formula (I), where Z is CH, NH, N, or O, and the other substituents are as defined in the specification. The specification also discloses more general compounds of the formula L-U1-M-U2-R, where each group is as defined in the specification. Also disclosed is a process for synthesizing the above compounds, and the use of the compounds as antibacterial agents, such as to treat bacterial infection.
Patent NZ-570538-A (NZ)
Title: Intravenous antiviral treatments
Inventor: BABU YARLAGADDA SUDHAKARA
IPC: A61K31/196
Filed: 2007-02-12
Abstract: Disclosed is the use of an effective ant-viral amount of a compound of formula Ia, wherein the substituents are defined in the specification, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for treating an influenza infection in a human by a single intravenous administration.
Patent NZ-574140-A (NZ)
Title: Protease screening methods and proteases identified thereby
Inventor: MADISON EDWIN L
IPC: C12N9/64
Filed: 2007-07-05
Abstract: Provided is a method for identifying or selecting a protease or catalytically active portion thereof that cleaves a cleavage sequence in a protein target substrate, comprising: a) contacting a collection comprising a plurality of mutant proteases and/or catalytically active portions of mutant proteases with a protease trap polypeptide, wherein: the protease trap polypeptide comprises a reactive site containing a cleavage sequence for the protein target substrate; whereby upon cleavage of amino acids in the reactive site by a protease or catalytically active portion thereof, the protease trap polypeptide forms a covalent bond with the protease or catalytically active portion thereof to form a complex; contacting is effected under conditions for cleavage of amino acids in the cleavage sequence included in the reactive site in the protease trap polypeptide by a protease or a catalytically active portion thereof in the collection; and upon cleavage of amino acids included in the reactive site of the protease trap polypeptide by a protease in the collection, the protease trap polypeptide forms stable complexes containing the protease trap polypeptide covalently linked to the protease or catalytically active portion thereof; and b) separating the complexed proteases from uncomplexed members of the collection; and c) identifying or selecting a protease or catalytically active portion thereof in a complex, to identify or select a protease or catalytically active portion thereof that cleaves the cleavage sequence in the protease trap polypeptide, thereby identifying or selecting a protease or catalytically active portion thereof that cleaves the protein target substrate. Further provided are combinations of mutant proteases and protease trap polypeptides for practising the invention.
Patent NZ-577786-A (NZ)
Title: AXMI-027, a delta-endotoxin genes and methods for its use
Inventor: CAROZZI NADINE
IPC: A01N63/50
Filed: 2006-04-03
Abstract: Disclosed are isolated nucleic acid and polypeptide sequences of delta-endotoxin AXMI-027. Also disclosed are vectors, host cells and transformed seeds comprising the nucleic acid sequence. The delta-endotoxin is a pesticidal agent particularly useful against Lepidoptera, Heteroptera and Coleoptera.
Patent NZ-577798-A (NZ)
Title: 5-cyano-4- (pyrrolo [2, 3b] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors
Inventor: MORTIMORE MICHAEL
IPC: A61P9/00
Filed: 2007-12-21
Abstract: Disclosed is a 5-CYANO-4- (PYRROLO [2, 3B] PYRIDINE-3-YL) -PYRIMIDINE and derivatives that are useful as protein kinase inhibitors.
Patent NZ-578334-A (NZ)
Title: Mask frame connected to face cushion via intervening clip
Inventor: WORBOYS DAVID JOHN
IPC: A61M16/06
Filed: 2008-04-16
Abstract: A mask assembly includes a frame 90, a cushion adapted to form a seal with the patient's face, and an intervening clip 70 that connects the cushion to the frame. The clip includes three clip portions 72, 74, 76 to engage corresponding portions 92 of the frame and a flange 78 extending around the perimeter and having three cut outs 80 adjacent the clip portions. The flange 78 engages within a retaining recess 96 of the cushion and the three cut outs interlock with a respective solid section 98 provided within the retaining recess 96.
Patent NZ-578479-A (NZ)
Title: Wave energy convertor with a submerged platform tethered to the sea bed with double acting pump operated by a buoyant and weighted float
Inventor: SMITH ALVIN
IPC: F03B13/18
Filed: 2007-11-13
Abstract: A double acting water pump mounted on a submerged column platform the water flow driving an energy generator, the platform is supported by a fixed structure on, or can be tethered via chain, rope or cable to a weight or anchored to, the water body bed. A submerged collar float surrounds the underwater platform with buoyancy greater than the weight of the overall energy convertor to maintain a taut tether. The pump contains a double acting reciprocating piston with valves, bearings and scaper seals. The piston shaft is connected or coupled to a surface float that contain compressed air controlled flood and drain valves to deactivate and re-activate the apparatus when wave and tide conditions are suitable. The surface float moves up with the waves due to buoyancy and down due to the mass of the float to pump water through the pump
Patent NZ-579376-A (NZ)
Title: Collapsible salad spinner in which basket and bowl collapse by folding along at least one living hinge
Inventor: CURTIN HEATHER
IPC: A47J43/24
Filed: 2009-08-28
Abstract: A salad spinner used to dry salad leaves, herbs or other similar food items is disclosed. The spinner comprises a bowl (30) and a basket (20) nested within it. Both bowl (30) and basket (20) collapse along a living hinge manufactured as part of each of their side walls.
Patent NZ-582407-A (NZ)
Title: Detection method for detecting presence of oestrus in a milking animal
Inventor: WILSON ALLAN WALTER
IPC: A01K29/00
Filed: 2010-12-21
Abstract: Disclosed is a method for detecting if oestrus is imminent or present in a milking animal. The method includes the steps of defining a processing area which encompasses two or more independent heat outputs including a portion of the rear of the milking animal, measuring an indicator of heat output from that area, and using the measurement obtained to determine if an oestrus condition is imminent or present.
Patent NZ-584949-A (NZ)
Title: Adjustable sphincter exerciser
Inventor: HUNG CHIEN-HSIUNG
IPC: A61H19/00
Filed: 2010-04-28
Abstract: An adjustable sphincter exerciser (Kegel Exerciser) that comprises a flexible tubular member 10 with a flange 11 above a base. The base contains a vibrating device 50 and a battery. The vibrating device is actuated by a pressure switch in the flexible tubular member 10. The flexible tubular member has a removable sleeve 20.
Patent NZ-589839-A (NZ)
Title: Azacarboline derivatives, preparation thereof, and therapeutic use thereof as kinase inhibitors
Inventor: ARENDT CHRISTOPHER
IPC: C07D471/14
Filed: 2009-06-11
Abstract: Disclosed herein are alpha-aza-beta-carboline derivatives of formula (I), defined by 1,7-diazacarbazole, 8-aza-beta-carboline or 9H-pyrrolo[2,3-b:5,4-c']dipyridine derivatives. Additionally disclosed are methods of preparation thereof, including key coupling reactions, such as Suzuki and Stille reactions, and cyclisation reactions, such as Buchwald-Hartwig and copper-catalysed cyclisations. Additionally disclosed is the use thereof in the treatment of cancer, chemotherapy, specifically relating to Pim kinase deregulation/inhibition.
Patent NZ-593224-A (NZ)
Title: Gene expression markers (fap) for colorectal cancer prognosis
Inventor: COWENS WAYNE
IPC: C12Q1/68
Filed: 2007-01-11
Abstract: Disclosed is a method of predicting clinical outcome for a human subject following surgical resection of colorectal cancer, the method comprising: a.) Determining a normalised level of RNA transcript of FAP, or an expression product thereof, in a biological sample comprising cancer cells obtained from said human subject; and b.) Predicting the likelihood of a positive clinical outcome for said human subject by comparing said normalised level to gene expression data obtained from colorectal cancer reference samples derived from patients with colorectal cancer, wherein increased normalised level of an RNA transcript of FAP, or an expression product thereof, is negatively correlated with an increased likelihood of a positive clinical outcome.
Patent NZ-594672-A (NZ)
Title: Process for the preparation of fischer - tropsch catalysts and their use
Inventor: TERORDE ROBERT JOHAN ANDREAS MARIA
IPC: B01J23/89
Filed: 2010-02-23
Abstract: Disclosed is a process for preparing a catalyst and catalyst precursor suitable for facilitating Fischer-Tropsch reactions, which comprises the steps: impregnating a particulate catalyst support with an organic cobalt or nickel compound in a carrier liquid, to form an impregnated intermediate and calcining the impregnated intermediate at a calcination temperature which is not above 400 degrees C, to obtain a calcined intermediate; and thereafter impregnating the calcined intermediate from the first preparation step, with an inorganic cobalt or nickel salt in a carrier liquid, to obtain an impregnated support, and calcining the impregnated support, to obtain the catalyst precursor, wherein none of the inorganic cobalt or nickel salt used in step 2 is present during step 1. Also disclosed is a hydrocarbon synthesis process which comprises contacting hydrogen with carbon monoxide at a temperature above 100 degrees C and a pressure of at least 10 bar over the catalyst to produce hydrocarbons and, optionally, oxygenates of hydrocarbons. Further disclosed is a hydrogenation process which comprises contacting hydrogen and an organic compound over the catalyst to hydrogenate the organic compound.
Patent NZ-595691-A (NZ)
Title: Drug delivery composition
Inventor: RUDDY STEPHEN B
IPC: A61K9/50
Filed: 2010-04-08
Abstract: Disclosed is a composition comprising: a semipermeable coating; particles of a medicament having an effective average particle size of less than or about 2 um (micrometres) and a surface stabilizer adsorbed on the surface of the medicament particles; and a solubilizing agent. Semi-permeable coatings can be selected from the group consisting of a controlled-porosity microporous coating, a water swellable coating. Surface stabilizer is selected from the group consisting of hydroxypropyl methylcellulose (HPMC), dioctyl sodium sulfosuccinate (DOSS), sodium lauryl sulfate (SLS), hydroxypropyl cellulose, polyvinylpyrrolidone, sodium deoxycholate, block copolymers based on ethylene oxide and propylene oxide, copolymers of vinylpyrrolidone and vinyl acetate, lecithin, polyoxyethylene sorbitan fatty acid esters, albumin, lysozyme, gelatin, macrogol 15 hydroxystearate, tyloxapol, and polyethoxylated castor oil.
Patent NZ-603606-A (NZ)
Title: Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups
Inventor: RUDOLPH ALEXANDER CHARLES
IPC: C07H21/00
Filed: 2011-05-27
Abstract: Disclosed is an oligomer comprising a backbone, a 3’ terminus, and a 5’ terminus, the backbone comprising a sequence of morpholine ring structures joined by intersubunit linkages, the morpholino ring structures having a 5’ end and a 3’ end according to the following structure (i), or a salt, tautomer or stereoisomer thereof, wherein B is, at each occurrence, independently a base-pairing moiety, the intersubunit linkages joining the 3’-end of one morpholino ring structure to the 5’- end of an adjacent morpholino ring structure, wherein the intersubunit linkages have the general structure (I), and wherein for at least one of the intersubunit linkages (I), W is, at each occurrence, independently S or O; X is, at each occurrence, independently -NR8R9 or -OR3; and Y is, at each occurrence, independently O or -NR10, R8 is, at each occurrence, independently hydrogen or an optionally substituted C2-C12 saturated or unsaturated hydrocarbon chain radical; R9 is at each occurrence, independently hydrogen, an optionally substituted saturated or unsaturated hydrocarbon chain radical, -Rb-Rc or optionally substituted aryl; R3 is, at each occurrence, independently hydrogen or an optionally substituted saturated or unsaturated hydrocarbon chain radical; R10 is, at each occurrence, independently hydrogen, an optionally substituted saturated or unsaturated hydrocarbon chain radical or -LNR4R5R7, wherein R8 and R9 may join to form a 5-18 membered, optionally substituted, mono or bicyclic heterocycle, or R8, R9 or R3 may join with R10 to form a 5-7 membered, optionally substituted, heterocycle; provided that i) R8 and R9 join to form a 5-18 membered, optionally substituted, mono or bicyclic heterocycle; or ii) R8, R9 or R3 join with R10 to form a 5-7 membered, optionally substituted, heterocycle. The disclosed oligonucleotide analogues are intended to have antisense or antigene performance, including having affinity for DNA and RNA without compromising sequence selectivity; having desirable pharmacokinetics and tissue distribution; and for improved cellular delivery and reliable and controllable in vivo distribution.
Patent NZ-611108-A (NZ)
Title: Methods of treating fgf21-associated disorders
Inventor: BOETTCHER BRIAN R
IPC: C07K14/50
Filed: 2011-11-17
Abstract: Disclosed is a polypeptide variant having a sequence selected from the group of the sequences defined in Table 1 of the specification. Also disclosed is the use of the polypeptides in the manufacture of a medicament for treating one or more of FGF21-associated disorders in a patient.
Patent NZ-629394-A (NZ)
Title: Synthetic brassica-derived chloroplast transit peptides
Inventor: ROBINSON ANDREW E
IPC: C12N15/82
Filed: 2013-02-01
Abstract: Disclosed is an isolated, recombinant or synthetic nucleic acid molecule comprising: a synthetic Brassica-derived nucleotide sequence that encodes a peptide comprising a contiguous amino acid sequence of a first Brassica chloroplast transit peptide, the peptide further comprising a contiguous amino acid sequence of a second chloroplast transit peptide.
Patent NZ-631006-A (NZ)
Title: Improvements to amphibious vehicles, their methods of manufacture, and use
Inventor: ROBERT BUTLER GOWER
IPC: B60F3/00
Filed: 2014-09-12
Abstract: An amphibious vehicle (100) including a wheel assembly (200, 400). The wheel assembly comprises at least one wheel and a drive motor. The wheel is rotatably mounted and the drive motor is coupled to the at least one wheel and configured to rotate a wheel. The drive motor can be positioned inside a sealed cavity within a housing. The cavity can be pressurised to prevent ingress of water. The wheel assembly can be capable of retracting to within the hull, and a cover can lie over top of the wheel in it’s retracted position. The drive motor is located adjacent to or within the hub of the wheel at the distal end of the leg.
Patent NZ-703217-A (NZ)
Title: Novel cyclic depsipeptide derivatives and harmful organism control agents comprising the same
Inventor: MITOMI MASAAKI
IPC: C07K11/02
Filed: 2013-06-13
Abstract: An aim of the present invention is to provide a novel cyclic depsipeptide derivative and a pest control agent comprising the same. According to the present invention, a compound represented by formula (1) or a stereoisomer thereof, a pest control agent comprising the same, and a production method thereof are provided.
Patent NZ-710726-A (NZ)
Title: Methods of treating autoimmune, respiratory and inflammatory disorders by inhalation of roflumilast n-oxide
Inventor: VAKKALANKA SWAROOP KUMAR
IPC: A61K9/16
Filed: 2014-01-28
Abstract: The present disclosure relates to pharmaceutical compositions useful for (and to a method of) treating autoimmune, respiratory and/or inflammatory diseases and conditions. The method involves administering to a subject in need thereof roflumilast N-oxide by inhalation. The present disclosure particularly relates to the treatment of asthma and chronic obstructive pulmonary disease (COPD) by administering roflumilast N-oxide by inhalation.