baber/WOPTO huggingface dataset:
Patent EP-0184110-A3 (EP)
IPC: C07C67/00
Filed: 1985-11-26
Abstract: Es wird ein neues Verfahren zur Herstellung von Alkyl­
thioacetamidinen der Formel (I) 
  
bereitgestellt,  
worin  
R = Alkyl  
X = Halogen  
und  
n = 0 oder 1.  
     Das neue Verfahren ist dadurch gekennzeichnet, daß 
man  
(a) Chloracetonitril der Formel (II)  
CICH₂CN (II)  
mit Ammoniumhalogeniden der Formel (III)  
NH₄X (III)  
in welcher  
X die oben angegebene Bedeutung hat,  
in Gegenwart von Katalysatoren und in Gegenwart von 
Verdünnungsmitteln bei Temperaturen zwischen -20°C und 
+30°C zu den Chloracetamidinen der Formel (IV) 
  
in welcher  
X und n die oben angegebenen Bedeutungen haben,  
umsetzt und  
(b) diese Verbindungen der Formel (IV) gegebenenfalls 
ohne Isolierung mit Alkylmercaptanen der Formel (V)  
RSH (V)  
in welcher  
R die oben angegebene Bedeutung hat,  
in Gegenwart von Säureakzeptoren und in Gegenwart von 
Verdünnungsmitteln, bei Temperaturen zwischen -20°C und 
+30°C und einem Druck zwischen 1 und 10 bar zu den 
Verbindungen der Formel (I) umsetzt.  
     Bei den Verbindungen der Formel (I) handelt es sich um 
Zwischenprodukte für die Synthese von hochwirksamen 
Insektiziden.
Patent EP-0151521-A3 (EP)
IPC: A61K8/49
Filed: 1985-01-18
Abstract: 3,3-dimethyl-1,5-dioxaspiro [5,5] undecane is useful in 
perfumery compositions. It can be made economically by 
reaction of cyclohexanone with neopentyl glycol in the 
presence of an acid, generally paratoluene sulphonic acid, 
under dehydrating conditions, generally by refluxing with a 
non-polar solvent.
Patent EP-0162725-A3 (EP)
Title: Chimeric plasmid vector
IPC: C12N15/74
Filed: 1985-05-24
Abstract: A chimeric plasmid vector contains (a) a tetracycline resistance gene region derived from the plasmid pAM alpha I of Streptococcus faecalis, (b) an ampicillin resistance gene region derived from the vector pACYC177 of Escherichia coli, (c) a DNA replication origin derived from said plasmid pAM alpha 1, (d) a DNA replication origin derived from said vector pACYC177, and (e) a polylinker region having a recognition and cleavage site for the restriction enzyme EcoRI at one terminal and a recognition and cleavage site for the restriction enzyme HindIII at the other terminal of the polylinker region, the plasmid vector having unique recognition and cleavage sites for the restriction enzymes BalI, HpaI and EcoRV, which sites are located in said tetracycline resistance gene region, and the plasmid vector having unique recognition and cleavage sites for the restriction enzymes PvuI, BglI and BanI, which sites are located in said ampicillin resistance gene region. The vector is useful for conveying a gene into a host cell, usually of a bacterium, and the host can then be employed in biosynthesis of industrial products.
Patent EP-0161982-A3 (EP)
Title: Procédé de fabrication de produits, notamment de panneaux composites, constitués au moins en partie de matériau expansé, ainsi que panneaux composites plans obtenus par la mise en oeuvre de ce procédé
IPC: B29C44/32
Filed: 1985-05-02
Abstract: a) Procédé de fabrication de produits, notamment de 
panneaux composites, constitués au moins en partie de ma­
tériau expansé, ainsi que panneaux composites plans obte­
nus par la mise en oeuvre de ce procédé;  
b) procédé, caractérisé en ce que l'on dépose le maté­
riau par coulée sous forme liquide sur la partie inférieure 
d'une feuille inférieure souple moulée en forme de U à bords 
relevés de manière à définir un canal de transfert continu;  
c) l'invention s'applique à un procédé de fabrication de 
produits constitués au moins en partie de matériau expansé.
Patent EP-0172778-A3 (EP)
Title: Perfectionnements aux mécanismes de chasse de w.c. du type à clapet à billes
IPC: E03D1/36
Filed: 1985-02-28
Abstract: Mécanisme de chasse d'eau de W.C. du type à clapet à 
billes caracpar le fait que les billes (29) et (30) sont de densité 
supérieure à un, que le clapet (13) entre en action en fin de 
course d'ouverture de la bonde, selon deux modes de 
réalisation, à savoir :  
a) Celui dans lequel le déplacement de la tige (7) d'un 
distributeur (6) s'effectue dans le prolongement de l'ouver­
ture manuelle de la bonde (2)  
b) Celui dans lequel le soulèvement de la bonde (22) est 
piloté par l'action d'un vérin hydraulique (23), que dans le 
but de supprimer la perception du bruit par le double 
enfermement de celui-ci, le mécanisme est logé à l'intérieur 
d'une enveloppe (39) est le même placé dans le réservoir 
normal (40) du W.C., que cette enveloppe (39) enmagasine 
l'eau de la chasse qui se vidange directement dans la cuvette 
par l'intermédiaire d'un conduit (43) de forme tronçonique, 
que des tiges associées à des vis agissant comme des 
étrésillons assurent la fixation rapide du mécanisme dans 
l'enveloppe (39) et de celle-ci dans le réservoir (40).
Patent EP-0180567-A3 (EP)
Title: Method for separating polypeptides
IPC: C07K1/14
Filed: 1985-10-28
Abstract: A method of separating a first polypeptide fraction from a second polypeptide fraction of a mixed solution is disclosed. A predetermined charged polymer is admixed with the mixed solution preferably in the presence of a neutral polymer. The charged polymer interacts with the first fraction to form a precipitate. The neutral polymer enhances the effectiveness of the charged polymer in precipitating the first fraction. By proper selection of the polymer combination the desired polypeptide fraction can be precipitated from solution leaving the other polypeptide fraction in solution or vice versa.
Patent EP-0203546-A3 (EP)
IPC: B62L1/16
Filed: 1986-05-23
Abstract: Die Erfindung betrifft eine Felgenbremse für Zweiräder 
und insbesondere Fahrräder, welche zwei drehbar gelager­
te Bremsarme mit je einem einen Bremsklotz tragenden 
Bremsschenkel sowie je einem sich diesem gegenüber in 
entgegengesetzter Richtung erstreckenden Betätigungs­
schenke und Mittel zur Betätigung dieser Bremsarme 
aufweist.  
     Bei der neuen Felgenbremse ist vorgesehen, dass ei­
ner der Bremsarme (erster Bremsarm) frei drehbar um ei­
nen Drehpunkt an dem Vorderradgabelkopf oder dem Rah­
menhinterbau gelagert ist, dass der andere Bremsarm 
(zweiter Bremsarm) mit Abstand von dem Drehpunkt des 
ersten Bremsarmes eine drehbare Lagerung um einen 
Drehpunkt an dessen Betätigungsschenkel hat und dass die 
von den Betätigungsmitteln ausgeübte Betätigungskraft an 
dem Betätigungsschenkel des zweiten Bremsarms angreift. 
Hierdurch wird vor allem erreicht, dass die neue Felgen­
bremse für Zweiräder mit allen Reifengrössen mit dem glei­
chen Hebelverhältnis gebaut werden kann, ohne dass sie 
seitlich zu ausladend wird.
Patent EP-0224268-A3 (EP)
IPC: C08J5/20
Filed: 1986-11-27
Abstract: The surface characteristics of dispersed 
particles such as vinyl resins are changed through the 
use of an anode electrolyte in an electrofilter. 
Accordingly, the properties of intermediate and final 
products made from these resins such as plastisols and 
fused films or coatings can be favorably changed. 
Properties which are altered include plastisol 
viscosity, film clarity, and foamability.
Patent EP-0194900-A3 (EP)
IPC: G01J5/02
Filed: 1986-03-17
Abstract: A pyroelectric ceramic having the composition:- 
  
where ⊘ is U (uranium) or Mn (manganese) and in which α is 
a number substantially within the range 0.01 to 0.10; x is a 
number substantially within the range 0.10 to 0.25; y is a 
number substantially within the range 0 to 0.4; z is a number 
substantially within the range 0 to 0.05 and δ is a number 
substantially within the range 0 to 0.06. Methods of fabricat­
ing the pyroelectric ceramic are also described.
Patent EP-0213911-A3 (EP)
Title: Compatible wide screen television system
IPC: H04N7/00
Filed: 1986-08-26
Abstract: A wide aspect ratio television system includes memories (40,42,44) for storing and recovering a video input signal in response to read and write clock pulses, respectively. Write clock pulses are deleted (410, Figure 4) to compress edge regions of a wide aspect ratio input signal and read clock pulses are deleted (Figure 8) to restore the signal to its original aspect ratio. The pattern of deleted pulses is preferably altered (404) on a line-by-line basis to reduce visible artifacts of signal decimation. In dual mode receivers which may include provisions for controlling edge blanking or effecting edge interpolation, the pattern of deleted clock pulses may be selected as a function of the type of received signals.
Patent EP-0230728-A3 (EP)
Title: Photolithography
IPC: G03F7/20
Filed: 1986-11-20
Abstract: Metal tellurium is vaporized under the atmosphere of oxygen gas and/or inert gas formed into a plasma by a high frequency power to thereby form a tellurium oxide (TeOx, 0 </= X </= 2) layer (9). The tellurium oxide layer formed in accordance with the present method is stabilized, and a suboxide having a high sensitivity which has been considered to be unsuitable as an optical recording medium due to the lack of stability can be utilized. High frequency power, gas pressure and vaporization speed of metal tellurium can be varied to thereby vary the value X of TeOx from 0 to 2. When the TeOx films whose value X thicknesswise is different are formed continuously within one and the same vessel and the vaporization speed is made to zero, oxidization of a film surface may be carried out. Thereby, the TeO2 film (10) may be formed on the surface, and an optical recording medium may be obtained which is extremely stable and has excellent adhesive properties between the substrates and between the layers.
Patent EP-0198803-A3 (EP)
IPC: G01N27/447
Filed: 1986-04-11
Abstract: A machine for performing blood electrophoresis with an 
automatic cycle of operations comprises a support (3) carry­
ing a washing vessel (5), a sample-holder (6) and a treatment 
vessel (8) all adjacent one another and aligned in a row, 
there being provided a carriage (20), movable on the support 
(3) and carrying a sampling comb (21) which, upon displace­
ment of the carriage (20) can be selectively introduced into 
the washing vessel, the sample-holder or the treatment ves­
sel, a microprocessor is provided to control the sequence of 
movements and dwell times of the comb (21) in order to per­
form the analysis operations in a repeatable manner.
Patent EP-0249751-A3 (EP)
IPC: B41N3/08
Filed: 1987-05-18
Abstract: Die Erfindung betrifft ein Feuchtmittelkonzentrat bestehend 
aus 
   a) 2,0 bis 28,0 Gew.-% eines wasserlöslichen, filmbildenden 
hydrophilen Kolloids,    b) 5,0 bis 25,0 Gew.-% eines wasserlöslichen oder mit Wasser 
mischbaren Glykols mit 2 bis 6 C-Atomen,    c) 0,5 bis 15,0 Gew.-% 2-Ethyl-1,3-hexandiol,    d) 0,02 bis 15,0 Gew.-% eines pH-Stabilisierungs-/Puffersystems, 
bestehend aus einer Mischung aus einer organischen Säure 
und einem wasserlöslichen Alkalimetallsalz einer organischen Säure 
und/oder Phosphorsäure,    e) 5,0 bis 32,0 Gew.-% eines wasserlöslichen Metall-nitrats 
und    f) 35 bis 65 Gew.-% Wasser.
Patent EP-0251315-A3 (EP)
Title: Naphthalene derivatives, process for their preparation and pharmaceutical compositions containing the same
IPC: C07C323/00
Filed: 1987-07-01
Abstract: Naphthalene derivative of the formula: <CHEM> wherein Ring A is a substituted or unsubstituted benzene ring; each of R<1> and R<2> is a group of the formula: -OR<5>, -NHR<5> or <CHEM> ; or either one of R<1> and R<2> is a lower alkoxy group and other one is a group of the formula: -OR<5>, -NHR<5> or <CHEM> ; each of R<3> and R<4> is a lower alkoxy group, or one of R<3> and R<4> is a lower alkoxy group and the other is a hydrogen atom; R<5> is a substituted alkyl group, a heterocyclic group, a cycloalkyl group, an alkyl group of at least 5 carbon atoms or alkenyl group; and each of R<6> and R<7> is hydrogen atom or a lower alkyl group and salts thereof are disclosed. Said naphthalene derivative (I) and its salts have excellent hypolipidemic activity and are useful for treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.
Patent EP-0253319-A3 (EP)
IPC: C07B61/00
Filed: 1987-07-09
Abstract: This invention relates to novel processes for the manufac­
ture of spiro-linked pyrrolidine-2,5-diones of formula; 
  
which have a potent inhibitory activity on aldose reductase and 
are useful for reduction and prevention of chronic diabetic com­
plications.  
     The invented processes are useful as improved and convenient 
method for a large scale manufacture.
Patent EP-0256314-A3 (EP)
IPC: G01N21/3504
Filed: 1987-07-15
Abstract: Man überträgt Licht über eine optische Faser zu einer Meßzelle, 
die das zu untersuchende Gas enthält, läßt es durch die Meßzelle 
hindurchtreten, überträgt das austretende Licht über eine op­
tische Faser zu einer Meßeinrichtung und vergleicht es dort mit 
einem Referenzlicht. Bekannt ist, hierbei die Absorption von 
Licht bei einer für Methangas charakteristischen Absorptionswel­
lenlänge auszunutzen. Die Aufgabe lautet nun, die Gaskonzentra­
tion nach einem anderen Prinzip zu bestimmen. Die Lösung besteht 
im wesentlichen darin, daß man die Veränderung der optischen 
Dichte des Gasgemisches in einer Meßküvette aus einem Vergleich 
mit der beim Zeeman-Effekt auftretenden Schwebungsfrequenz des 
Lichtes ermittelt. Dazu wird der Resonator eines Lasers axial 
von einem Magnetfeld durchsetzt, womit er zwei polarisierte 
Lichtstrahlen gering unterschiedlicher Frequenz aussendet, die 
sich zu einer Schwebung überlagern, deren Frequenz man über 
Fotodioden mißt. Man trennt die beiden Frequenzen voneinander, 
führt die eine durch die Meßküvette und die andere durch eine 
Referenzküvette, überlagert beide wieder, zählt die Frequenz der 
Meßschwebung hoch und vergleicht diese mit der Frequenz der 
Referenzschwebung am Ausgang des Lasers.
Patent EP-0261430-A3 (EP)
IPC: C08K3/36
Filed: 1987-08-26
Abstract: A biaxially oriented polyester film formed from 
an intimate mixture comprising (1) an aromatic polyester, 
and (2) 0.01 to 4 % by weight, based on the aromatic 
polyester, of spherical fine particles of silica having 
(a) an average particle diameter of 0.05 to 4 µm, (b) a 
particle diameter ratio, defined by the ratio of maximum 
diameter to minimum diameter, of from 1.0 to 1.2, and (c) 
a relative standard deviation (σ) of particle size, of 
up to 0.5. A biaxially oriented polyester film formed 
from an intimate mixture comprising (1) an aromatic 
polyester, (2) 0.005 to 3 % by weight, based on the 
aromatic polyester, of spherical fine particles of silica 
having the same properties as the above-mentioned (a), 
(b) and (c), and (3) 0.005 to 3 % by weight, based on the 
aromatic polyester, of inert fine particles having an 
average particle diameter of 0.01 to 3 µm and not exceed­
ing the average particle diameter of the spherical fine 
particles of silica. The biaxially oriented films are 
useful for a magnetic recording medium.
Patent EP-0264743-A3 (EP)
IPC: C10G1/00
Filed: 1987-10-09
Abstract: The description concerns a process for the preparation 
of a synthetic fuel derived from coal, consisting of 
mixtures of asphaltenic hydrocarbons and oils, the said 
process comprising pretreatment of the coal whereby the 
coal is caused to react in an aqueous suspension with 
carbon monoxide in the presence of a hydroxide or al­
kali metal carbonates (preferably sodium or potassium) at 
a temperature of between 350 and 430°C, preferably between 
370 and 400°C, the reaction time being between 5 and 
60 minutes, preferably between 5 and 30 minutes, with 
as necessary separation out of any derivatives obtained 
in this manner from coal that has not reacted and of 
the minerals contained in the coal itself, and with catalytic 
hydrogenation with hydrogen and if necessary with a solvent 
that is a donor of hydrogen,in the presence of a catalyst 
that is in itself already known.
Patent EP-0268950-A3 (EP)
IPC: A61K8/58
Filed: 1987-11-13
Abstract: Die vorliegende Erfindung betrifft eine hautpflegende 
bzw. hautschützende Zusammensetzung mit einem Gehalt an 
hochviskosen Polydimethylsiloxanen, die gegebenenfalls 
end- und/oder mittelständige OH-, Vinyl-, Phenyl- oder 
Alkylgruppen mit 2 bis 6 C-Atomen aufweisen, mit einer 
Viskosität von 10⁶ bis 5.10⁷ mPa.s und leicht flüchtigen 
oder zyklischen Siloxanen.
Patent EP-0254461-A3 (EP)
IPC: C07C239/00
Filed: 1987-07-13
Abstract: A method of combatting plant nematodes which com­
prises applying to the soil or the plant, an effective amount of 
a compound of general formula I 
  
wherein  
Ar, X, R₁, R₂, R₄ and R₆ have the meanings given in the des­
cription, is described. Some of the compounds also form part 
of the invention.
Patent EP-0261871-A3 (EP)
IPC: C10G3/00
Filed: 1987-09-16
Abstract: A two step process for the production of high octane products 
for motor gasoline from C₃ to C₆ alkenes comprises (a) reacting the 
C₃ to C₆ alkenes with water in a molar ratio of alkene to water of 
at least 3:1 over an acid hydration catalyst to form oligomers of 
the alkenes, ethers and optionally alcohols and (b) reacting C₃ to 
C₆ alkenes remaining from step (a) with isobutane in a second step 
to form alkylate. The feed to the process can be a C₃/C₄ stream 
from a cat. cracker or steam cracker. In one embodiment the feed 
contains isobutane and the process of step (a) is controlled so as 
to give a molar ratio of isobutane to alkenes in the product from 
step (a) suitable as a feed for the akylation without the necessity 
of adding isobutane.
Patent EP-0267727-A3 (EP)
Title: Gas resonance device
IPC: F25B9/00
Filed: 1987-11-03
Abstract: A thermally driven gas resonance device comprises a resonance tube (3) which expands in cross-section along its length from one end to the other, a heat source (2) located at the one end of the resonance tube, and means (2, 4) to trigger oscillations in a gas in the resonance tube. The heat source (2) is preferably a pulsed heat source having a pulse repetition frequency corresponding to a resonant frequency of the gas resonance tube (3). The mechanical energy produced in the oscillating gas in the gas resonance device may be used to operate a pressure swing gas separator by including a bed (16) of molecular sieve material in the other end of the resonance tube (3). Alternatively, the mechanical energy may be used to drive a heat pump (19). In this case a heat sink (21) is located at the other end of the resonance tube (3), a regenerator (20) is also located adjacent the other end, and means (8) on the side of the regenerator (20) towards the heat source (2) effect heat exchange between the gas in the resonance tube (3) and a source of low grade heat.
Patent EP-0272099-A3 (EP)
IPC: B41M5/337
Filed: 1987-12-15
Abstract: A recording material contains in a color forming layer 
a colorless electron donating dye precursor (e.g. a fluoran), 
an electron-accepting developer (e.g. a phenol) and 0.1 
- 15 g/m² of a compound of formula (I) and/or (II)  
Ar₁XC n H 2n YC m H 2m ZAr₂      (I)  
wherein Ar₁ and Ar₂ each represents an aromatic ring which 
may contain an O or S atom: X represents -O-, -S- and 
Y is -O-, -S- or -CO₂- when Z is -CO-; or X is -O- and 
Y is -CO₂-, -SO₂- or -SO-, when Z is -O-; and  n  and  m  each 
is an integer of from 1 to 6.  
Ar₁XC n H 2n YC m H 2m YC n H 2n XAr₂      (II)  
wherein Ar₁, Ar₂,  n  and  m  are as above; X is -S- or -O-; 
and Y is -CO₂-.  
     The ratio of compound (I) or (II) to electron-acceptor 
is 1:10 to 1:0.1; the compounds may have 16-28 C atoms 
and melt at 70-190°C.  
     The material can be heat-sensitive, for use in a 
facsimile machine, to give good color images.
Patent EP-0281975-A3 (EP)
IPC: D06M13/463
Filed: 1988-03-05
Abstract: Die zur Behandlung von Textilien nach dem Waschen vor­
gesehenen Weichspülmittel enthalten als Wirkstoff eine 
Kombination von Carbonsäuren und Aminen und/oder quar­
tären Ammoniumverbindungen mit einem langen Alkyl- ­
oder Alkenylrest. Diese Wirkstoff-Kombination ist 
leicht und preiswert verfügbar und verleiht den behan­
delten Textilien einen weichen vollen Griff.
Patent EP-0315013-A3 (EP)
IPC: A61F13/15
Filed: 1988-10-24
Abstract: Bei einer Hygiene-Artikel (10) 
mit einer Innenlage (12) aus einem feuchtigkeitsdurch­
lässigen Material, einer Polsterlage (14) 
aus einem Feuchtigkeit aufnehmenden, 
saugfähigen material und einer Außenlage (18) 
besteht die feuchtigkeitsundurch­
lässige Außenlage (18) aus einem Vliesstoff, 
der auf einer Seite mit einer dün­
nen Schicht aus einem thermoplastischen, 
hochpolymeren Werkstoff, insbeson­
dere einem Hotmelt auf der Basis von Polyethylen, EVA oder ATP, versehen 
ist.  
     Zur Herstellung eines solchen Hygiene-Artikels 
werden gleichzeitig die Innenlage (12) 
aus dem feuchtigkeitsdurchlässigen Material und die Vliesstoff-­
Bahn, die auf einer Seite mit dem thermoplastischen, hochpolymeren Werk­
stoff beschichtet ist, aud die zentrale Polsterlage aufkaschiert.
Patent EP-0300521-A3 (EP)
Title: Method and apparatus for ptp pocket formation
IPC: B29C51/14
Filed: 1988-06-16
Abstract: A method for PTP Pocket forming on a sheet (10) which 
requires a delicate care for handling is disclosed. Combination 
of local and discriminative preparative heating of the pocket-regions 
of freshly unrolled sheet (10) while leaving the rest of the 
sheet in a cooled state in a lattice structure, preliminary 
expanding said regions up to about 70% of the volume of the 
recesses of the female die (32) by pressing heated plugs (50) to the 
region and supplying compressed-air to the expanded region 
enabled the method. Details of the temperature control on 
various steps of the method and an apparatus suitable for 
embodying the method as well as a mean for attaining a vertually 
complete thermal equibrium over the preparative heting station 
are also disclosed.
Patent EP-0304123-A3 (EP)
IPC: B41M5/41
Filed: 1988-08-12
Abstract: A thermal transfer medium which has a heat meltable or heat-­
sublimable ink layer on one side of a stretched polyamide film which 
mainly consists of polytetramethyleneadipamide and has a melting point 
of at least 270◊C. The film shows good heat resistance and non-­
sticking properties.
Patent EP-0276166-A3 (EP)
IPC: C07K14/59
Filed: 1988-01-22
Abstract: A hormone composition for producing superovulation 
in cattle. The composition has a particular ratio of 
follicle stimulating hormone (FSH) and luteinizing hormone 
(LH) which produces an optimum superovulation response in 
cattle. The composition can be produced from animal 
pituitary glands or by recombinant DNA procedures.
Patent EP-0294937-A3 (EP)
Title: Novel cinnamoylamide derivatives
IPC: A61K31/16
Filed: 1988-05-06
Abstract: A cinnamoylamide derivative of the general formula: <CHEM>  [wherein,   (i) R<1>, R<2> and R<3>, which may be the same or different, each represents a halogen atom, a straight-chain or branched-chain alkoxy group of from 1 to 7 carbon atom(s), a straight-chain or branched-chain alkyl group of from 1 to 7 carbon atom(s) or a nitro group, and one of R<4> and R<5> represents a methyl group and the other represents a hydrogen atom, or (ii) one of R<1>, R<2> and R<3> represents 4-isobutyl, 4-butyl, 4-propyl, 4-butoxy or 4-sec-butyl, and the other two each represent a hydrogen atom, R<4> represents a methyl group and R<5> represents a hydrogen atom] and non-toxic salts thereof possess inhibitory activity on 5 alpha -reductase, indicative of utility for treating and/or preventing alopecia, acne or prostatic hypertropy. E