baber/WOPTO huggingface dataset:
Patent MX-2021002057-A (MX)
Title: CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITY.
Inventor: SHORT JAY M
IPC: A61K39/00
Filed: 2019-08-20
Abstract: A method of producing a conditionally active polypeptide from a parent polypeptide, which comprises steps of: (i) evolving the parent polypeptide by introducing mutations into the parent polypeptide to produce mutant polypeptides that have a pI the same as or lower than a pI of the parent polypeptide; (ii) subjecting the mutant polypeptides to a first assay under a normal physiological condition to measure the activity of the mutant polypeptides under the normal physiological condition and a second assay under an aberrant condition to measure the activity of the mutant polypeptides under the aberrant condition, wherein the normal physiological condition and the aberrant condition are the same condition but having different values; and (iii) selecting the conditionally active polypeptide from the mutant polypeptides which exhibits an increased activity in the second assay compared to the same activity in the first assay. Conditionally active polypeptides and uses are also provided.
Patent MX-2021003066-A (MX)
Title: Improving return signal detection in a light ranging and detection system with pulse encoding.
Inventor: HALL DAVID
IPC: G01S17/88
Filed: 2019-08-14
Abstract: Described herein are systems and methods for improving detection of a return signal in a light ranging and detection system (LiDAR). The method includes the following steps at the LiDAR system: encoding and transmitting a sequence of pulses based on a user signature. Then, receiving a multi-return signal based on a reflection off objects of the sequences of pulses. The multi-return signal may be decoded based on the user signature, and then authenticated the via a correlation calculation. The user signature may determine an amplitude of a first pulse in the sequence of pulses, an amplitude of a second pulse of the sequence of pulses, and an interval between the first pulse and the second pulse. A bit representation of the user signature is orthogonal to a bit representation of another user signature of another LiDAR system. The user signature may be dynamically adjusted by the LiDAR system.
Patent MX-2021003089-A (MX)
Title: Immunotherapy with a*01 restricted peptides and combination of peptides against cancers and related methods.
Inventor: WEINSCHENK TONI
IPC: C07K7/06
Filed: 2019-09-18
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo andtransfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Patent MX-2021003340-A (MX)
Title: Partition wall.
Inventor: ICHINO YUSUKE
IPC: E04B2/74
Filed: 2019-07-04
Abstract: Provided is a partition wall which uses as small as possible as number of fire resistant cover materials, thereby making the partition wall easily workable, and in which the leakage of hot air from lateral joints are effectively prevented to make the partition wall highly fire resistant. A partition wall 100 has: a plurality of intermediate columns 10; and a pair of walls sandwiching the plurality of intermediate columns 10 and having a first wall 30A and a second wall 30B, which are formed by vertically and horizontally arranging a plurality of plasterboards 20. Each of the first wall 30A and the second wall 30B is a single-layer wall comprising a plurality of plasterboards 20. The first wall 30A and the second wall 30B have longitudinal joints 60 and lateral joints 70, and the intermediate columns 10 are present on the rear surfaces of the longitudinal joints 60. Joint base materials 40 which have a T-shaped lateral cross-sectional shape, have rear surface pieces 41, have protrusion pieces 42 protruding in the thickness direction of plasterboards 20, and have flame shielding properties are provided at the lateral joints 70. The plasterboards 20, the joint base materials 40, and the intermediate columns 10 are not fastened by common screws 50.
Patent MX-2021004255-A (MX)
Title: Aerosol provision device.
Inventor: WRIGHT JEREMY
IPC: A24F40/10
Filed: 2019-10-16
Abstract: An electronic aerosol provision device, the device comprising a housing for receipt of an aerosol generating component, the housing comprising an air inlet and an aerosol outlet, wherein the device is configured to induce a reduction in the temperature of an aerosol when exiting the air inlet.
Patent MX-2021004853-A (MX)
Title: Non-dairy cheese composition and process for preparation thereof.
Inventor: RAY JOYDEEP
IPC: A23C20/02
Filed: 2019-10-31
Abstract: The present invention relates to a non-dairy cheese composition comprising dietary fiber; non- animal protein, calcium and lipid, wherein the composition is devoid of additives, and wherein the composition has a moisture content of more than 45 wt% and less than 60 wt%. The invention also relates to a method preparing such compositions and uses thereof.
Patent MX-2021005058-A (MX)
Title: Winch for a vehicle having damage protection.
Inventor: KUKULA GLEN L
IPC: B66D1/46
Filed: 2019-10-30
Abstract: A winch and method for operating the winch includes a winch body having a first drum support (720), a second drum support (722) and a drum (205) rotatably coupled to the first drum support and the second drum support. The winch further comprises a plurality of gears (610) coupled to the second drum support and the drum. A motor (204) is coupled to the drum through the plurality of gears A motor cover (726) is coupled to the first drum support. A gear cover (730) is coupled to the second drum support and houses the plurality of gears therein. A supplemental cover (740, 740A, 740B) covers at least a portion of the motor cover or a portion of the gear cover or both.
Patent MX-2021006067-A (MX)
Title: Logic circuitry.
Inventor: LINN SCOTT A
IPC: G06F21/44
Filed: 2019-04-05
Abstract: A logic circuitry package for a replaceable print apparatus component comprises an interface to communicate with a print apparatus logic circuit, and at least one logic circuit. The logic circuit may be configured to identify, from a command stream received from the print apparatus, parameters including a class parameter, and/or identify, from the command stream, a read request, and output, via the interface, a count value in response to a read request, the count value based on identified received parameters.
Patent MX-2021006412-A (MX)
Title: Methods for treating cancer in models harboring esr1 mutations.
Inventor: BIHANI TEERU
IPC: A61K31/137
Filed: 2019-12-06
Abstract: Disclosed herein are methods of treating a drug resistant estrogen receptor alphaÂ¬ positive cancer in a subject having a mutant estrogen receptor alpha, the method comprising administering to the subject a therapeutically effective amount of elacestrant, or a pharmaceutically acceptable salt or solvate thereof, wherein the mutant estrogen receptor alpha comprises one or more mutations selected from the group consisting of D538G, Y537X<sub>1</sub>, L536X<sub>2</sub>, P535H, V534E, S463P, V392I, E380Q and combinations thereof, wherein: Xi is S, N, or C; and X<sub>2</sub> is R or Q. In some embodiments, the drug resistant estrogen receptor alpha-positive cancer is selected from the group consisting of breast cancer, uterine cancer, ovarian cancer, and pituitary cancer.
Patent MX-2021006619-A (MX)
Title: Tyrosine kinase inhibitors, compositions and methods there of.
Inventor: CHEN JIE
IPC: A61K31/519
Filed: 2019-12-06
Abstract: The present invention relates to compounds of Formula (I), methods of using the compounds as Trk inhibitors, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections. (I).
Patent MX-2021007267-A (MX)
Title: Agent for improving heat resistance or salt tolerance of plants.
Inventor: KIM JONGMYONG
IPC: A01N37/02
Filed: 2019-12-20
Abstract: The present invention provides an agent for improving the heat resistance or salt tolerance of plants, the agent containing acetic acid or a salt thereof or a solvate of the same.
Patent MX-2021008997-A (MX)
Title: Data packets comprising random numbers for controlling fluid dispensing devices.
Inventor: NESS ERIK D
IPC: B41J2/175
Filed: 2019-02-06
Abstract: In some examples, a fluid dispensing device includes a reservoir containing a fluid, fluidic actuators, and an interface to receive a data packet comprising information to control activation of the fluidic actuators, the data packet comprising a random number generated by a random number generator.
Patent MX-2021009320-A (MX)
Title: Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests.
Inventor: FLASINSKI STANISLAW
IPC: C07K14/325
Filed: 2017-04-12
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
Patent MX-2021011598-A (MX)
Title: Use of mir101 or mir128 in the treatment of seizure disorders.
Inventor: DURING MATTHEW
IPC: C12N15/63
Filed: 2020-07-13
Abstract: Methods of treating a seizure disorder in a patient in need thereof are provided which include delivering to the patient an effective amount of a composition that increases the level of microRNA-101 molecules in brain cells of the patient. Methods of treating a seizure disorder in a patient in need thereof are provided which include delivering to the patient an effective amount of a composition that increases the level of microRNA-128 molecules in brain cells of the patient. Methods of treating a seizure disorder in a patient in need thereof are provided which include administering a vector encoding microRNA-101, pri-miR101 or pre-miR101 to the patient. Methods of treating a seizure disorder in a patient in need thereof are provided which include administering a vector encoding microRNA-128, pri-miR128 or pre-miR128 to the patient. In embodiments, increased levels of microRNA-101 and/or microRNA-128 cause improvement in one or more symptoms of the seizure disorder.
Patent MX-2021011659-A (MX)
Title: Systems, devices, and methods for driving a wheel of a bicycle.
Inventor: RAY SOMNATH
IPC: B62M6/75
Filed: 2020-03-25
Abstract: A clamping mechanism is provided, the clamping mechanism have two clamps, a tensioning conduit corresponding to each of the clamps, and an actuator for simultaneously tensioning the two clamps by way of the tensioning conduits. Each clamp has a bracing element and a gripping segment, and when the clamps are tensioned along the tensioning conduit, the gripping segment of each clamp is drawn towards the corresponding bracing element. Also provided is a bicycle drive assembly, the assembly has two clamps for fixing to a bicycle, a drive mechanism for driving a bicycle wheel, and two elongate supports extending from the drive mechanism to corresponding clamps. When applied to a bicycle, a wheel of the bicycle passes partially between the elongate supports.
Patent MX-2022000390-A (MX)
Title: Macrocyclic spirocycle derivatives as mcl-1 inhibitors.
Inventor: DIELS GASTON STANISLAS MARCELLA
IPC: A61P35/00
Filed: 2020-07-07
Abstract: The present invention relates to pharmaceutical agents of formula (I) useful for therapy and/or prophylaxis in a subject, pharmaceutical composition comprising such compounds, and their use as MCL-1 inhibitors, useful for treating diseases such as cancer.
Patent MX-2022001586-A (MX)
Title: A coated structure with a monitoring system, a monitoring system, and a method for monitoring a condition of a coated structure.
Inventor: BARGALLO JOSEP PALASI
IPC: G01N17/02
Filed: 2020-08-12
Abstract: A coated structure with a monitoring system, the structure comprising a base having a base surface, a coating joined to the base surface in a base interface and extending in a thickness direction to an outer coating surface, a sensor comprising at least one electrode embedded in the coating, an I/O device configured to generate an input signal in the sensor and to read an output signal from the sensor, a data logger configured to log the output signal from the I/O device, and a computer unit configured to use the logged signal from the data logger. To provide improved information related to the condition of the structure or coating, the computer unit is configured to determine at least two separate indexes, each index related to a property of the coating or the structure.
Patent MX-2022005860-A (MX)
Title: Customizable communications platform.
Inventor: LEE DAVID
IPC: G06F15/16
Filed: 2020-11-13
Abstract: In an example method, a communications platform generates a plurality of logical structures. The communication platform receives, from a first user, first content to be shared within a first logical structure of the plurality of logical structures. The communications platform determines one or more second users associated with the first logical structure, and transmits contents of the first logical structure including the first content to the one or more second users.
Patent MX-2022007194-A (MX)
Title: Oral care compositions.
Inventor: DUBOVOY VIKTOR
IPC: A61Q11/00
Filed: 2020-07-13
Abstract: Described herein are complexes comprising a cationic antibacterial agent and a metal salt; oral care compositions comprising same; along with methods of making and using these complexes and compositions.
Patent MX-2022007326-A (MX)
Title: Oral delivery systems based on in situ forming protein/polysaccharide coacervates.
Inventor: CAILLARD ROMAIN
IPC: A61K47/42
Filed: 2020-12-16
Abstract: An oral delivery system based on in situ forming protein/polysaccharide coacervates is described herein. The system comprises an active ingredient dispersed in a dry, homogenous powder mixture of a protein powder and a polysaccharide powder, which is able to form a protein/polysaccharides complex coacervate in situ upon immersion in gastric fluid, thereby conferring gastric protection and/or modified-release to the active ingredient. Varying the ratio of protein powder to polysaccharide powder in the oral delivery system varies the level of gastric protection and/or rate of release to the active ingredient. The ability of the system described herein to be based on natural and/or naturally-derived biopolymers provides commercial advantages in terms of regulatory approval and/or growing consumer demand for such products.
Patent MX-2022007637-A (MX)
Title: Handling loss or removal of devices in a mesh network.
Inventor: KNODE GALEN EDGAR
IPC: H04W24/04
Filed: 2020-12-18
Abstract: A load control system may include control devices configured to communicate via a network. The network may include router devices for enabling communication of messages throughout the network. A control device may operate as a router device in the network. The control device may receive advertisement messages from a leader device in the network. When the leader device fails to communicate advertisement messages within a predefined period of time to other control devices that are operating as router devices in the network, one or more router devices may be identified as backup-leader devices to take over operation as the leader device in the network. When a control device that has the role of a leader device or router device is intentionally deactivated, the control device may perform a deactivation process that is specific to the role of the control device on the network.
Patent MX-2022007663-A (MX)
Title: Thienyloxazolones and analogues.
Inventor: KNOBLOCH THOMAS
IPC: C07D413/04
Filed: 2020-12-17
Abstract: The present disclosure relates to substituted thiophene carboxamides derivatives, their use for controlling phytopathogenic microorganisms and compositions comprising thereof.
Patent MX-2022008086-A (MX)
Title: Preparation and/or formulation of proteins cross-linked with polysaccharides.
Inventor: SOMMER-KNUDSEN JENS
IPC: A61L27/24
Filed: 2013-05-22
Abstract: Therapeutic compositions and/or formulations are provided, comprising: at least one cross- linked protein matrix, wherein the at least one cross-linked protein matrix comprises at least one protein residue and at least one saccharide-containing residue, and methods of producing the same. The cross-linked protein matrix may be derived from cross-linking a full length or substantially full length protein, such as tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin, and/or derivatives or combinations thereof, with a saccharide containing cross-linking agent, such as a polysaccharide cross-linking agent derived from, for example, hyaluronic acid or a cellulose derivative. The therapeutic compositions may be administered topically or by injection. The present disclosure also provides methods, systems, and/or kits for the preparation and/or formulation of the compositions disclosed herein.
Patent MX-2022009610-A (MX)
Title: Composite panel edge treatments and joints and cargo body having same.
Inventor: FENTON GARY L
IPC: B62D65/02
Filed: 2015-06-04
Abstract: A cargo body includes sidewalls constructed of pairs of panels secured together at respective joints. Each panel is an assembled panel having a core, an interior skin, and an exterior skin. In some cases, each joint is formed to include overlapping edge portions of first and second ones of the adjacent pair of panels. Each of the overlapping edge portions has a thickness less than 20 percent of a total panel thickness of the corresponding one of the adjacent pair of panels such that the joint formed thereby defines a recess between co-facing edge portions of the first and second ones of the adjacent pair of panels. A profile insert defining a longitudinal channel is positioned in the recess defined by the overlapping edge portions at each joint. Each joint is secured by fixedly attaching the profile insert to the overlapping edge portions.
Patent MX-2022010327-A (MX)
Title: Tasquinimod or a pharmaceutically acceptable salt thereof for use in combination therapy.
Inventor: GABRILOVICH DMITRY
IPC: A61K31/454
Filed: 2021-03-03
Abstract: A combination comprising tasquinimod, or a pharmaceutically acceptable salt thereof, and at least one further compound selected from a proteasome inhibitor, an immunomodulatory imide, and an antibody, for use as a in the treatment of multiple myeloma. A kit comprising tasquinimod and a package insert with instructions for using tasquinimod in combination with at least one further compound selected from a proteasome inhibitor, an immunomodulatory imide, and an antibody, to treat multiple myeloma in an individual. Tasquinimod for use in the treatment of multiple myeloma, in combination with a further compound selected from a proteasome inhibitor, an immunomodulatory imide, and an antibody.
Patent MX-PA00006408-A (MX)
Inventor: HIMMELMAN GUNILLA
IPC: A61F13/15
Filed: 2000-06-28
Abstract: An absorbent article, such as a diaper, sanitary napkin, incontinence protector, wound dressing, bed protector, etc., comprising an absorbent structure, the structure containing a superabsorbent material in combination with hydrophilic fibers and wherein the material superabsorbent has a renewable and / or biodegradable raw material content of at least 20% by weight, calculated on the dry weight of the superabsorbent material, characterized in that the superabsorbent material has a phase angle d = 8 [deg.] defined as the phase shift between the deformation and effort measured in reologic measurements
Patent MX-PA00009318-A (MX)
Title: Winder for a thin metal strip.
Inventor: LADDA DIETER
IPC: B21C47/06
Filed: 1999-03-20
Abstract: The invention relates to a winder for a thin metal strip (1) comprising a winder mandrel (2), a feeding element (3) for tangentially feeding the metal strip (1) to the winder mandrel (2), and at least six pressure rollers (7) with pressure roller axles (8) for guiding the metal strip (1) around the winder mandrel (2). The pressure rollers (7) are arranged around the winder mandrel (2), are lodged in the tightening elements (4), and can be tightened against the winder mandrel (2) by means of tightening drives (6).
Patent MX-PA01001997-A (MX)
Title: Manufacture of pocketed compound nested coil springs.
Inventor: WELLS THOMAS J
IPC: B68G9/00
Filed: 1999-08-24
Abstract: A system and method for manufacturing pocketed compound nested coil springs (10) includes inserting a compressed, preferably pocketed, smaller coil spring (18) into a horizontally oriented larger coil spring (24) either prior to compressing and inserting the outer coil spring (24) into pocket material (58) or after (Fig. 3) the larger coil spring (24) has been pocketed thereby requiring the first spring (18) to be inserted into and through an opening (84) in the pocket material.
Patent MX-PA01002639-A (MX)
Title: Sink roll blade apparatus used in continuous molten metal plating apparatus and method for preventing occurrence of dents.
Inventor: SACHIHIRO LIDA
IPC: C23C2/00
Filed: 2001-03-13
Abstract: An apparatus installed in a molten metal plating line includes a blade pressed against a roll dipped in a molten metal plating bath, in which a metal strip travels. The apparatus removes substances deposited on a surface of the roll. The apparatus also includes an arm for supporting the blade, and a screw member disposed above the plating bath so as to traverse it and moving along an axis of the roll in the bath for removing substances deposited on the roll in the molten metal plating bath. Floats and/or weights are mounted on the arm so as to adjust a press force of the blade applied to the roll in the molten metal plating bath. A method for preventing the occurrence of dents on a molten-metal-plated steel strip using the apparatus is also disclosed.
Patent MX-PA01006452-A (MX)
Title: Dynamic control of image enhancement.
Inventor: JEFFREY OWEN ALLENDER
IPC: H04N5/45
Filed: 2001-06-22
Abstract: A method for controlling video peaking in a video display apparatus operable to display first (Ymain) and second image (Ypip) signal simultaneously. The method comprises the steps of combining the first (Ymain) and second image (Ypip) signals to form a simultaneous display signal (301); and independently controlling the video peaking in accordance with each of the first (Ymain) and second (Ypip) images combined to form the simultaneous display signal (301).
Patent MX-PA01007018-A (MX)
Title: Methods for treating ovarian cancer, poly(phosphoester) compositions, and biodegradable articles for same.
Inventor: DANG WENBIN
IPC: A61K9/14
Filed: 1999-12-23
Abstract: Biodegradable polymer compositions suitable for intraperitoneal administration to treat a mammalian subject having ovarian cancer are described. The composition comprising: (a) at least one antineoplastic agent and (b) a biodegradable phosphoester polymer wherein the polymer composition provides extended release of the antineoplastic agent into the peritoneum of the subject; wherein the polymer composition increases the median survival rate from the cancer by at least about 10%, as compared with the median survival rate obtained by administration of a composition comprising the same dosage of the antineoplastic agent without the biodegradable polymer. Solid articles and methods for treating ovarian cancer are also described.