baber/WOPTO huggingface dataset:
Patent CA-3034905-A1 (CA)
Title: Method for producing radiopharmaceutical composition
Inventor: KIRIU Masato
IPC: A61K51/00
Filed: 2019-02-26
Abstract: A simple method for producing a clinically applicable radiopharmaceutical composition containing 1-(2,2-dihydroxymethyl-3- [18F]fluoropropyl)-2-nitroimidazole ([18F]DiFA) or a salt thereof as an active ingredient, is provided which includes a synthesis step of obtaining a crude product of [18F]DiFA from a labeling precursor compound for [18F]DiFA; and a purification step of purifying the crude product, in which the purification step includes purifying [18F]DiFA using two or more different types of reverse phase solid phase extraction cartridges.
Patent CA-3035108-A1 (CA)
Inventor: SCHUH SUSANNE
IPC: A23L33/00
Filed: 2017-09-13
Abstract: An infant formula comprising protein, carbohydrate and fat, wherein the major source of protein is potato protein.
Patent CA-3035301-A1 (CA)
Inventor: MAGUIRE MICHAEL
IPC: B05B1/14
Filed: 2017-08-31
Abstract: The current subject matter includes an adaptive electrospray device that creates consistent output when operating in atmosphere (e.g., not a vacuum). For example, the current subject matter includes an adaptive system that can monitor two current reference points (at the emitter and counter-electrode, respectively), determine a change in emitter current that will account for the parasitic losses, and adjust the emitter current accordingly. In addition, the current subject matter includes a high- throughput adaptive electrospray device having an array of emitters that rapidly switches the electrical potential of different emitters in an array on and off at a predetermined sequence that mitigates or eliminates interference from neighboring emitters. Related apparatus, systems, techniques and articles are also described.
Patent CA-3035756-A1 (CA)
Title: Revetement acoustiquement transparent
Inventor: BURY RAFAEL
IPC: C09D7/61
Filed: 2017-09-06
Abstract: Il est décrit une formulation pour un revêtement transparent sur le plan acoustique prévu pour l'utilisation sur un substrat acoustique, comme une cloison sèche perforée comprenant un liant pouvant se disperser dans l'eau et des particules de remplissage relativement grandes. La formulation se caractérise par une concentration élevée de pigment, une viscosité élevée, un degré de fluidification élevé et une capacité de séchage rapide qui lui permettent de se vaporiser en gouttelettes qui maintiennent leur individualité lorsqu'elles entrent en contact les unes avec les autres et forment ainsi une structure poreuse.
Patent CA-3035840-A1 (CA)
Title: Dispositif d'ancrage et de suspension osseux orthopedique
Inventor: SCHULZ CHRISTOPH
IPC: A61B17/04
Filed: 2017-09-11
Abstract: L'invention concerne une dispositif d'ancrage et de suspension osseux orthopédique (10, 30) avec une tête (11, 31) qui, sur sa face supérieure (12, 32), présente une ouverture (13) d'un alésage central (14) pour recevoir un dispositif d'expansion, et, adjacent à la face inférieure (15, 35) de la tête (11, 31), un manchon (16, 36) qui est réalisé sous la forme d'une cheville à expansion pour ancrer le dispositif d'ancrage et de suspension osseux dans l'os. Le dispositif d'ancrage et de suspension osseux est caractérisé en ce que la tête (11 31) présente une embase (18, 38) qui fait saillie vers l'extérieur au-delà du manchon (16, 36), l'embase présentant de préférence des trous (19) pour la fixation de sutures de fixation et, sur sa circonférence extérieure, au moins un évidement (20, 40) pour des greffons.
Patent CA-3037648-A1 (CA)
Inventor: BAUMSTARK DANIELA
IPC: G01R33/465
Filed: 2017-12-12
Abstract: The invention relates to a method for analyzing an NMR spectrum of a lipoprotein-containing sample, comprising the following steps: a) defining a spectral range to be analyzed of at least 0.5 ppm of an NMR spectrum of a lipoprotein-containing sample (16), b) fitting a first spectral function of a first individual lipid component (21) and at least one further spectral function of a further individual lipid component (22) into the whole spectral range to be analyzed, wherein the first spectral function (21) represents at least a part of an NMR spectrum of the first individual lipid component taking into account the behavior of the first lipid component in the surroundings of a lipoprotein particle of a first defined lipoprotein class or lipoprotein subclass; wherein the further spectral function (22) represents at least a part of an NMR spectrum of the further individual lipid component taking into account the behavior of the further lipid component in the surroundings of a lipoprotein particle of the same defined lipoprotein class or lipoprotein subclass; determining a concentration or an amount of the first individual lipid component and the further individual lipid component and therefrom a concentration or an amount of the first defined lipoprotein class or lipoprotein subclass in the lipoprotein-containing sample and optionally of each other defined lipoprotein class or lipoprotein subclass based on the fitting operations of step b).
Patent CA-3041650-A1 (CA)
Title: 1,2,4-triazolones 4,5-annelees
Inventor: GRADL STEFAN NIKOLAUS
IPC: C07D471/04
Filed: 2017-10-25
Abstract: La présente invention concerne des composés triazolone de formule générale (I) : (I), où R1, R2, R3, R4 et R5 sont tels que définis ici, des procédés de préparation desdits composés, des composés intermédiaires utiles pour préparer lesdits composés, des compositions et combinaisons pharmaceutiques comprenant lesdits composés et l'utilisation desdits composés pour fabriquer des compositions pharmaceutiques destinées au traitement ou à la prophylaxie de maladies, en particulier de maladies hyperprolifératives et/ou inflammatoires, en monothérapie ou en association avec d'autres principes actifs.
Patent CA-3041979-A1 (CA)
Inventor: OKANO FUMIYOSHI
IPC: A61P35/00
Filed: 2017-10-27
Abstract: La présente invention concerne : un conjugué obtenu par liaison d'un anticorps, ou d'un fragment de celui-ci, qui est immunologiquement sensible à la protéine CAPRIN-1 à un facteur d'activation immunitaire; et une composition pharmaceutique pour le traitement et/ou la prévention du cancer qui est caractérisée en ce qu'elle comprend ledit conjugué en tant que composant efficace, et qui a une activité antitumorale qui est supérieure à des anticorps classiques ou des conjugués classiques d'anticorps et de facteurs d'activation immunitaire.
Patent CA-3043054-A1 (CA)
Inventor: MILROY WILLIAM
IPC: H01P5/107
Filed: 2019-05-13
Abstract: A waveguide-to-parallel-plate twist transition includes at least one waveguide-to-parallel plate twist transition element comprising an input port comprising an input waveguide portion, the input waveguide portion configured to orient an E-field of an electromagnetic wave along a first plane, and an output port comprising a multi-mode parallel plate portion, the multi-mode parallel plate portion configured to orient an E-field of an electromagnetic wave along a second plane, wherein an angle of orientation of the second plane is different from an angle of orientation of the first plane. The twist transition further includes at least one intermediate discrete twist waveguide stage coupling each input waveguide portion to the output multi-mode parallel plate portion, wherein at least one intermediate discrete twist waveguide stage is configured to orient an E-field of an electromagnetic wave along a third plane, wherein an angle of orientation of the third plane is between the angle of orientation of the first plane and the angle of orientation of the second plane
Patent CA-3043326-A1 (CA)
Title: Specialty pulp with high intrinsic viscosity
Inventor: HAMED OTHMAN A
IPC: D21C9/00
Filed: 2017-11-14
Abstract: A method for making a specialty fiber by activating pulp in an alkaline aqueous medium, then reacting it a water-soluble, multi-functional reagent able to bridge neighboring cellulose chain within a single fiber. The resultant specialty cellulose fibers have high intrinsic viscosity and may be used to make cellulose ethers, cellulose acetate, and viscose.
Patent CA-3044126-A1 (CA)
Title: Degradable polymer and method of production
Inventor: CHAPMAN GRAHAM
IPC: C08L23/02
Filed: 2017-11-21
Abstract: The present invention provides a degradable polymer composition comprising: (a) a polyolefin; (b) two or more transition metal compounds in a total amount of from 0.15 to 0.6 wt%, (c) a mono- or poly-unsaturated C14-C24 carboxylic acid, or an ester, anhydride or amide thereof, in an amount of from 0.04 to 0.08 wt%; (d) a synthetic rubber in an amount of from 0.04 to 0.2 wt%; and, optionally: (e) dry starch in an amount of from 0 to 20 wt%; and/or (f) calcium oxide in an amount of from 0 to 1 wt%; and/or (g) a phenolic antioxidant stabilizer in an amount of from 0 to 0.2 wt%; wherein the two or more transition metal compounds are selected from iron, manganese, copper, cobalt and cerium compounds and wherein the transition metals in the two or more transition metal compounds are different.
Patent CA-3045304-A1 (CA)
Inventor: NASLUND BRIAN BRENT
IPC: G01M3/26
Filed: 2019-06-05
Abstract: A device for use in a leak check test of an air data system includes a device body, an opening extending into the device body with the opening being configured to allow a probe to be at least partially inserted into the opening, and walls surrounding the opening with the walls being situated to seal a port in the probe such that air is prevented from flowing into or out of the port while the probe is inserted into the opening. A method of performing a leak check test includes covering the port with the device to seal the port, heating air within a gas path in the air data system, measuring the change in pressure of the air resulting from an increase in temperature of the air, and determining whether the air data system is sealed depending on the change in pressure of the air.
Patent CA-3046680-A1 (CA)
Inventor: ROTHBERG JONATHAN M
IPC: C12Q1/6806
Filed: 2017-12-19
Abstract: Procédés de chargement d'une molécule à étudier dans un puits d'échantillons. Selon certains aspects, l'invention concerne des procédés de chargement d'une molécule à étudier dans un puits d'échantillons impliquant le chargement d'une molécule à étudier dans un puits d'échantillons en présence d'un agent de rassemblement et/ou d'un agent de condensation. Selon certains aspects, l'invention concerne des procédés de chargement d'un modèle de séquençage dans un puits d'échantillons.
Patent CA-3047674-A1 (CA)
Inventor: RAMO VIRPI
IPC: C10M101/02
Filed: 2017-12-21
Abstract: The invention provides a hydraulic fluid composition comprising a hydrocarbon component comprising more than 5 wt% of naphthenic oil and up to 95 wt% of renewable or recycled isoparaffinic oil, based on the total weight of the composition. The hydraulic fluid composition is useful as an arctic hydraulic fluid composition, shock absorber or automatic transmission fluid.
Patent CA-3048836-A1 (CA)
Title: Procede et systeme de recuperation de metal au moyen d'un separateur helicoidal
Inventor: VALERIO THOMAS A
IPC: B03B5/52
Filed: 2017-11-14
Abstract: L'invention concerne un procédé et des systèmes de récupération de métaux à partir d'un matériau contenant du métal. Certains modes de réalisation du procédé selon l'invention comprennent au moins une des trois étapes suivantes : (1) dimensionnement, (2) séparation au moyen du séparateur hélicoïdal et (3) collecte. Un système selon l'invention peut exécuter ces étapes.
Patent CA-3048865-A1 (CA)
Inventor: CHEN ZHENGUANG
IPC: G01J5/02
Filed: 2019-07-09
Abstract: A temperature measuring method capable of switching calculation based on displacement detection comprises a temperature measuring instrument and a displacement detecting unit for detecting a change of position of the temperature measuring instrument. When the displacement detecting unit feeds back that the temperature measuring instrument is under an inactive state, a point calculation formula is used to calculate and obtain a body temperature value. When the displacement detecting unit feeds back that the temperature measuring instrument is under an active state, a scanning calculation formula is used to calculate and obtain the body temperature value. Therefore, a more precise body temperature value is obtained. Meanwhile, the temperature measuring operation is facilitated to be simple and easy. The operation requirement of temperature measuring is reduced and the practicality is high.
Patent CA-3049428-A1 (CA)
Inventor: SLUSHER BARBARA
IPC: C07D487/04
Filed: 2018-01-05
Abstract: Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) and their use for treating neurodegenerative diseases, such as, neurodegenerative diseases associated with high levels of ceramide, including, but not limited to Alzheimer's disease (AD), HIV-associated neurocognitive disorder (HAND), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS), and, in other aspects, for treating cancer, are provided.
Patent CA-3049912-A1 (CA)
Title: Modulators of estrogen receptor proteolysis and associated methods of use
Inventor: QIAN YIMIN
IPC: A61P35/00
Filed: 2018-01-26
Abstract: The present disclosure relates to bifunctional compounds, which find utility as modulators of estrogen receptor (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a cereblon, Von Hippel-Lindau ligase-binding moiety, Inhibitors of Apotosis Proteins, or mouse double-minute homolog 2 ligand, which binds to the respective E3 ubiquitin ligase, and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.
Patent CA-3052406-A1 (CA)
Title: Pulley structure and method for manufacturing pulley structure
Inventor: SHIMAMURA HAYATO
IPC: F16C33/20
Filed: 2018-03-28
Abstract: The present invention provides a pulley structure (10) provided with: a tubular outer rotating body (2) having a belt (B) looped thereon; an inner rotating body (3) which is disposed radially inside the outer rotating body (2) and which is rotatable relative to the outer rotating body (2); and a torsional coil spring (4) which is arranged in a spring accommodating space (8) formed between the outer rotating body (2) and the inner rotating body (3). At least in a state in which the pulley structure (10) has not been operated even once, a grease (200) containing an antirust agent is applied to an opposing surface (34) of the inner rotating body 3 opposing an inner peripheral surface (42) of the torsional coil spring (4).
Patent CA-3052512-A1 (CA)
Title: Door lock and handle assembly
Inventor: MORSTATT SCOTT
IPC: E05B9/04
Filed: 2018-03-30
Abstract: A door handle assembly that allows for easy removal and switching of handles is disclosed. Such an arrangement may provide the flexibility to change handle orientation and interchange handles based on a user's circumstances or preferences such as when a door handle is configured as a lever having a curved shape. Further, the door handle may be configured as a door lock having a keypad access control. The face of the keypad accessible from outside the door may include auxiliary battery terminals to provide the user with easy accessibility for providing temporary power to the door lock with an auxiliary battery should the installed batteries housed within the door lock fail to provide sufficient power.
Patent CA-3052597-A1 (CA)
Inventor: CHIU HSIEN-HSIANG
IPC: G06F15/00
Filed: 2015-05-29
Abstract: In a virtual, three-dimensional working space a gesture sensing input device is operative to translate hand gestures of a user into commands for operating a computer or various machines.  The input device tracks the user and recognizes the user's hand gestures by correlating the gestures with defined "puzzle-cell" positions established in virtual working space zones, the "puzzle-cell" positions being mapped for converting the hand gestures into computer commands.  In the virtual working space, a mouse zone, keyboard zone, and hand sign language zone are defined. The working space is further defined by virtual, layered control zones whereby a plane in which a zone lies may be used to determine whether an actuation has occurred by the crossing of a boundary.
Patent CA-3055264-A1 (CA)
Title: Appareil de traitement transcutane par gaz
Inventor: BERTA ZSOLT ZOLTAN
IPC: A61H33/00
Filed: 2018-01-24
Abstract: L'appareil selon l'invention est conçu pour un traitement transcutané par gaz. L'appareil (10) comprend une enceinte à paroi rigide (20) et ayant une ouverture supérieure et au moins un panneau pouvant être ouvert, un siège (25) est disposé à l'intérieur de l'enceinte (20), et l'enceinte (20) comprend au moins une unité de mesure de concentration de gaz (29a), et l'enceinte (20) comprend encore une entrée de gaz (30) pour alimenter le gaz de traitement et une sortie de gaz (31) pour décharger le gaz de traitement; une unité d'alimentation en gaz (40) couplée à l'entrée de gaz (30) de l'enceinte (20) par l'intermédiaire d'un tuyau (41 ) et à travers une vanne (42) commandable interposée; et un réservoir de gaz (50) raccordé à l'unité d'alimentation en gaz (40). L'appareil comprend aussi une unité de ventilation (60) raccordé à la sortie de gaz (31) de l'enceinte (20) par l'intermédiaire d'une vanne (63) commandable interposée, ladite unité de ventilation (60) étant couplée par l'intermédiaire d'un autre tuyau (62) à un espace (70) séparée hermétiquement de la pièce contenant l'enceinte (20), et ladite unité de ventilation (60) étant conçue de telle sorte qu'elle peut évacuer le volume entier du gaz de traitement depuis l'espace intérieur de l'enceinte (20) dans au plus 5 secondes. L'appareil comprend en outre une unité de commande (80) pour recevoir les signaux de l'unité de mesure de concentration de gaz (29a) et pour commander le fonctionnement des vannes (42, 63) et ladite unité de ventilation (60) sur la base d'au moins les signaux de l'unité de mesure de concentration de gaz (29a).
Patent CA-3056267-A1 (CA)
Inventor: YANG NING
IPC: H04W24/08
Filed: 2017-03-23
Abstract: Disclosed in the present application are a switching method, a network device and a terminal device, the method comprising: a first network device obtains a measurement result for a link, the link comprising a link between the first network device and a first terminal device as well as a link between the first network device and a second terminal device; and the first network device determines a first switching scheme for the first terminal device and/or a second switching scheme for the second terminal device according to the measurement result. Thus, it is possible to enable a relay terminal device and a remote terminal device to continue carrying out effective relay transmission therebetween after the relay terminal device and remote terminal device carry out cell switching.
Patent CA-3057462-A1 (CA)
Title: Alternative two column hru design with rich reflux
Inventor: EMBRY DALE L
IPC: B01D53/14
Filed: 2018-03-20
Abstract: The invention relates to a system, method and apparatus for removing heavies from natural gas. Natural gas and an external rich reflux gas feed are processed in a single column refluxed absorber. A bottoms stream is routed to a first heat exchanger and then to a stabilizer column where an overhead stream from the stabilizer column is routed through a condenser for partial separation into an overhead stream. A rich solvent may be introduced to the stabilizer column. The overhead stream is routed through a condenser for partial separation into a stabilizer reflux and a second overhead stream lights. The second overhead stream lights is routed to a heat exchanger and then routed to a partial condenser where the stream is separated into a heavies rich reflux stream, a distillate stream and heavies treated natural gas stream. The rich reflux is routed through a heat exchanger and the rich reflux is pumped to the single column refluxed absorber to be introduced into the single column refluxed absorber as the external rich reflux gas feed.
Patent CA-3058117-A1 (CA)
Title: Anticorps se liant specifiquement a la region n-terminale de la lysyl-arnt synthetase exposee sur une membrane cellulaire
Inventor: KIM SUNGHOON
IPC: A61K39/395
Filed: 2018-03-27
Abstract: La présente invention concerne un anticorps se liant spécifiquement à une région N-terminale de la lysyl-ARNt synthétase qui est exposée sur la membrane cellulaire et son utilisation et, plus particulièrement, un anticorps ayant une certaine région de détermination complémentaire (CDR) stipulée dans la description et se liant spécifiquement à un épitope comprenant la séquence de SEQ ID NO : 97 dans dans une région N-terminale de la lysyl-ARNt synthétase (KRS) ou son fragment, une utilisation de l'anticorps ou de son fragment dans la suppression des métastases et le diagnostic du cancer et une composition pharmaceutique pour la prévention ou le traitement d'une maladie liée à la migration des cellules immunitaires. Une affinité de liaison spécifique bien supérieure à une région N-terminale KRS exposée sur la membrane cellulaire, l'anticorps ou ses fragments selon la présente invention sont efficaces pour le diagnostic du cancer, ont des effets anticancéreux et d'inhibition de métastases et peuvent être très utiles pour prévenir ou traiter une maladie liée à la migration des cellules immunitaires.
Patent CA-3060493-A1 (CA)
Inventor: HEMBROUGH TODD
IPC: G01N27/00
Filed: 2019-10-29
Abstract: Methods are provided for detecting and quantifying the DLL1, DLL3, JAG1, JAG2, Notch1, Notch 2, Notch 3, Notch 4, and/or DLL4 proteins in biological samples, such as a formalin fixed paraffin embedded tissue samples, using mass spectrometry. Additionally, methods are provided for treating cancer based upon the level of the DLL1, DLL3, JAG1, JAG2, Notch1, Notch 2, Notch 3, Notch 4, and/or DLL4 proteins in the biological samples.
Patent CA-3060818-A1 (CA)
Inventor: MUNARO RAFAEL
IPC: B65F1/00
Filed: 2019-11-01
Abstract: A reusable, multi-purpose collection bin for waste collection, particularly at special events requiring waste collection such as concerts, festivals, sporting events, and any other outdoor or indoor event where trash collection is desired. The bin easily contracts simply by pulling upward on the top panels through the grasping holes on the top of the bin.
Patent CA-3061148-A1 (CA)
Title: Bong enclosure device
Inventor: GARCIA MASSIMO
IPC: A24F1/02
Filed: 2019-11-08
Abstract: ABSTRACT An invention comprising of a two-piece system that creates an air-tight enclosure within either entry point of a tobacco or marijuana bong. The device eliminates the ability to detect any residual effects that are involved with any prior consumption of tobacco or marijuana such as the scent associated with burning. As well, the air-tight enclosure provides an optimal storage for the stagnant water that otherwise would have to be emptied between uses. Alleviating the need to empty the bong allows for optimal travel without the worry of leakage of fluids when the bong enclosure device is in use. CA 3061148 2019-11-08
Patent CA-3062950-A1 (CA)
Title: Magnetic eyeglasses attachments comprising decorative elements and/or functional elements including lenses
Inventor: JIN JING
IPC: G02C9/00
Filed: 2018-03-21
Abstract: Magnetic eyeglasses attachments, the magnetic eyeglasses attachments comprise decorative elements and/or functional elements including lenses.