baber/WOPTO huggingface dataset:
Patent MX-2022009196-A (MX)
Title: A method for harq transmission.
Inventor: FU QIANG
IPC: H04L1/16
Filed: 2020-04-10
Abstract: This document generally relates to transmitting a feedback message from a first node to a second node, where the message indicates both a detection result of receiving at least a portion of a transport block, and addition information that indicates to the second node how to set one or more parameters for a subsequent transmission. In various embodiments, the message includes a value, such as an M-bit binary value that indicates both the detection result and the additional information.
Patent MX-2022009916-A (MX)
Title: Apparatus for improved transfection efficiency and/or protein expression and method of use thereof.
Inventor: J HENRY WILLIAM
IPC: A61N2/00
Filed: 2021-03-25
Abstract: A method and apparatus for improving transfection efficiency in eukaryotic cells is provided. The method includes the steps of providing a transfection mixture including an agent associated with at least one amphiphilic construct suitable for transfection. Adding the transfection mixture to one or more eukaryotic cells to form a transfection complex and allowing the transfection complex to undergo a transfection process to form one or more transfected cells. The method also includes the step of directing pulsed electromagnetic signals provided at any or any combination of a pre-determined frequency, at a pre-determined pulse rate, or at a pre-determined power, at the transfection mixture at step a) prior to creating the transfection complex, at the transfection complex in step b), at the transfection complex in step c) and/or at the transfected cell complex after step c).
Patent MX-2022010538-A (MX)
Title: Modified binding polypeptides for optimized drug conjugation.
Inventor: QIU HUAWEI
IPC: A61K47/68
Filed: 2021-02-26
Abstract: Engineered antibodies that are stable and can be conjugated to a ligand or drug at a ligand/drug to antibody ratio of above 3, making these conjugates suitable for treatment of a variety of indications, are provided. Methods of producing these engineered antibodies are also provided. In a first embodiment, the antibody comprises a first engineered reactive amino acid residue at position 274 according to the numbering of the EU index of Kabat and a second engineered reactive amino acid residue at position 339, 360, 384, 385, 422 and/ or 440. In a second embodiment, the antibody comprises a first engineered reactive amino acid residue at position 339 according to the numbering of the EU index of Kabat and a second engineered reactive amino acid residue at position 290, 360, 384, 385, 422 and/or 440. In a third embodiment, the antibody comprises a first engineered reactive amino acid residue at position 118 according to the numbering of the EU index of Kabat and a second engineered reactive amino acid residue at position 274, 339, 384, 385, 422 and/or 440. In a fourth embodiment, the antibody comprises a first engineered reactive amino acid residue at position 384 according to the numbering of the EU index of Kabat and a second engineered reactive amino acid residue at position 118, 274, 290 and/or 339. In a preferred embodiment, the engineered reactive amino acid residue is cysteine.
Patent MX-2022011576-A (MX)
Title: Nlrp3 modulators.
Inventor: HARRIS JASON
IPC: A61K31/64
Filed: 2021-03-15
Abstract: Described herein are NLRP3 modulators and methods of utilizing NLRP3 modulators in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
Patent MX-2022014163-A (MX)
Title: Il-2 fusion polypeptide compositions and methods of making and using the same.
Inventor: ZEIDAN TAREK A
IPC: A61K38/20
Filed: 2021-05-10
Abstract: Provided herein are compositions comprising polypeptides comprising a circularly permuted interleukin-2 (IL-2) fused to the extracellular portion of an IL-2RÎ± chain, and methods of making and using such compositions.
Patent MX-PA00006381-A (MX)
Title: Thermal nasal filter.
Inventor: ARTURO ENRIQUE GARCIA ARIAS
IPC: A62B23/00
Filed: 2000-06-15
Abstract: 1) A nasal filter useful for preventing and relieving airway diseases caused by triggering asthma factors and environmental contingence in large cities, which acts as a filter purifying contaminated air and as a heater by means of a regulated heat generation cell, thereby converting cold air from the exterior into regulated thermal air to the interior of the nasal mucosa by passing the air through the heating cells, thereby preventing dripping of the nose during cold weather and dryness of nasal mucus walls. The disclosure further aids to correct curved nose by means of two oval crests or accessories placed in the upper portion of the filtering caps, which are introduced in the upper inner cavernosum area of the nose and upwardly raised, thereby allowing the entrance of air flow. The purpose of the disclosure is aiding the nose to filter and purify the contaminated cold air of the cities, generating regulated heat to the interior of the nose as the trachea and bronchi are not able to maintain a constant temperature and which are sensitive to suffer disorders because of weather changes. 2) The advantage the disclosure presents is a secure filtration contained in the filtering packages of both caps located in the core of the filter of the design and structure, which are different from those existing in the market.
Patent MX-PA01002271-A (MX)
Title: Method and apparatus to synthesize and defeat video copy protection signals.
Inventor: QUAN RONALD
IPC: G11B5/027
Filed: 1999-09-01
Abstract: A method and apparatus for defeating copy protection signals in a video signal, and also for providing copy protection signals for a video signal, is disclosed. The defeat technique generally utilizes a particular pulse position shifting, modulation, etc., of AGC, normal sync and/or pseudo sync pulses to increase the separation between the pulses. Various embodiments are disclosed including selective shifting of the relative positions of either the sync/pseudo sync or AGC pulses, trimming portions of the sync/pseudo sync and/or the AGC pulses and narrowing of either the sync/pseudo sync and/or the AGC pulses, all to provide the selective position separation between the sync/pseudo sync and AGC pulses. The copy protection technique includes various embodiments for dynamically varying the sync/pseudo sync and AGC pulse separation by applying a modulation of the above position shifting, trimming and/or narrowing techniques over selected time periods to cycle from the copy protection condition to the copy protection defeat condition, back to the copy protection condition.
Patent MX-PA01003853-A (MX)
Title: Synergistic effect of a sulfonylurea and/or non-sulfonylurea kchannel blocker, and a phosphodiesterase 3 type inhibitor.
Inventor: JANICE CATHERINE PARKER
IPC: A61K31/4015
Filed: 2001-04-11
Abstract: The present invention provides methods of treating non-insulin dependent diabetes mellitus, insulin resistance, Syndrome X, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, polycystic ovary syndrome, cataracts, hyperglycemia, or impaired glucose tolerance, the methods comprising the step of administering to a patient having or at risk of having non-insulin dependent diabetes mellitus, insulin resistance, Syndrome X, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, polycystic ovary syndrome, cataracts, hyperglycemia, or impaired glucose tolerance a synergistic amount of: 1) a sulfonylurea, a non-sulfonylurea K+ ATP channel blocker, or a sulfonylurea and a non-sulfonylurea K+ ATP channel blocker; and 2) a cAMP phosphodiesterase type 3 inhibitor. The present invention also provides kits and pharmaceutical compositions that comprise: 1) a sulfonylurea, a non-sulfonylurea K+ ATP channel blocker, or a sulfonyl urea and a non-sulfonylurea K+ ATP channel blocker; and 2) a cAMP phosphodiesterase type 3 inhibitor. The present invention also relates to kits and pharmaceutical compositions that comprise 1) a sulfonylurea, a non-sulfonylurea K+ ATP channel blocker, or a sulfonylurea and a non-sulfonylurea K+ ATP channel blocker; 2) a cAMP phosphodiesterase type 3 inhibitor; and 3) an additional compound useful for the treatment of non-insulin dependent diabetes mellitus, insulin resistance, Syndrome X, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, polycystic ovary syndrome, cataracts, hyperglycemia, or impaired glucose tolerance.
Patent MX-PA01008142-A (MX)
Title: Amide compounds and medicinal use thereof.
Inventor: USHIO HIROYUKI
IPC: A61K45/06
Filed: 2000-02-10
Abstract: The present invention relates to a compound of the formula <CHEM> wherein R<1> is substituted aryl, heteroaryl and the like, R<2> and R<3> are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.
Patent MX-PA01008948-A (MX)
Title: Paste biodegradable cockroach-pesticide.
Inventor: MA GUADALUPE SOSA RIVERA
Filed: 2001-08-17
Abstract: The present invention discloses a method for killing cockroaches, which is characterized in that it comprises home ingredients: sugar, onion, flour and grease, and boric acid as an active ingredient. Upon mixing together said ingredients a paste is formed, which results pleasant to the cockroaches, which consume said paste destroying the digestive system of the same. Said paste is used as an insect bait, killing all type of cockroaches, it further causes a chain reaction, i.e., when a cockroach consumes the paste it feels satisfied, then goes to the nest and die there; other cockroaches consume the rests of the insect and the effect continues until all the insects are killed, thereby completely protecting the room where the paste was placed. Said product has advantages such as: not being toxic, presenting a simple manner of applying the same, being 100% biodegradable, it is not necessary to move the kitchen furniture when applying the same, being an environmentally-friendly product, b eing cost-effective since customers acquire the product once a year.
Patent MX-PA01010965-A (MX)
Title: Antimicrobial treatment for swimwear.
Inventor: ROGER BRADSHAW QUINCY III
IPC: A61L15/46
Filed: 2001-10-26
Abstract: An absorbent swimwear garment having an antimicrobial agent based on hydantoin chemistry for the purpose of eliminating or reducing the level of bacteria in swim water. During initial product use, the absorbent swimwear garment is able to contain urine and bowel movements, similar to ordinary diapers and training pants. When the swimwear garment is submersed in swim water, particularly chlorinated or brominated water, the antimicrobial agent is stabilized and is thereby able to eliminate E. coli and other fecal bacteria from the swim water.
Patent MX-PA02004450-A (MX)
Title: Additive concentrate.
Inventor: DAVID ROY KENDALL
IPC: C10L1/222
Filed: 2000-11-03
Abstract: Additive ConcentrateThe invention provides an additive concentrate which comprises an oil soluble hydrocarbyl poly(oxyalkylene) aminocarbamate having a number average molecular weight (Mn) in the range 600 to 10,000 having at least one basic nitrogen atom wherein said hydrocarbyl group contains 1 30 carbon atoms, and an oil soluble hydrocarbyl amine of formula R NH2, wherein R represents a group R or a group R CH2 , wherein R represents a hydrocarbyl group having a number average molecular weight (Mn) in the range 750 to 6,000; a gasoline composition containing such additive concentrate; and its preparation; and a method of operating a spark ignition engine using such gasoline composition.
Patent MX-PA02005275-A (MX)
Title: A pyrrolidineacetamide derivative alone or in combination for treatment of cns disorders.
Inventor: LAMBERTY YVES
IPC: A61K31/197
Filed: 2000-11-27
Abstract: A use of (S) ( ) agr; ethyl 2 oxo 1 pyrrolidineacetamide for the manufacture of a medicament for treatment of particular diseases and new pharmaceutical compositions comprising (S) ( ) agr; ethyl 2 oxo 1 pyrrolidineacetamide.
Patent MX-PA02007543-A (MX)
Title: Novel biarylcarboxamides.
Inventor: PHILLIPS EIFION
IPC: A61P25/16
Filed: 2001-02-15
Abstract: A compound of formula (I), wherein A represents (II), (III), (IV) or (V), D represents oxygen or sulfur; E represents a single bond, oxygen, sulfur, or NR10; R represents hydrogen or methyl; Ar1 represents a 5 or 6 membered aromatic or heteroaromatic ring containing zero to three nitrogen atoms, zero or one oxygen atom, and zero or one sulfur atom; Ar2 represents a 5 or 6 membered aromatic or heteroaromatic ring containing zero to three nitrogen atoms, zero or one oxygen atom, and zero or one sulfur atom or; an 8 , 9 or 10 membered fused aromatic or heteroaromatic ring system containing zero to three nitrogen atoms, zero to one oxygen atom, and zero to one sulfur atom; the aromatic rings Ar1 and Ar2 are optionally substituted with one or three substituents selected from: halogen, C1 4alkyl, C2 4alkenyl, C2 4alkynyl, CN, NO2, NR1R2, CH2NR1R2, OR3, CH2OR3, CO2R4, CF3; R1, R2 and R3 are independently C1 4alkyl, aryl, heteroaryl, C(O)R5, C(O)NHR6, C(O)R7, SO2R8 or R1 and R2 may together be (CH2)jG(CH2)k where G is oxygen, sulfur, NR9, or a bond; j is 2 to 4; k is 0 to 2; R4, R5, R6, R7, R8, R9, and R10 are independently C1 4alkyl, aryl, or heteroaryl; or an enantiomer thereof and pharmaceutically acceptable salts thereof; with the provisos that: (1) if D represents oxygen, E represents a single bond, and A represents (II) and either Ar1 or Ar2 represents a pyrazole ring, then all optional substituents on the pyrazole ring shall be hydrogen; and (2) if Ar1 represents a pyridine ring, Ar2 represents an aryl ring, and A represents (II), then all optional substituents on the pyridine ring shall be hydrogen; and (3) formula (I) does not represent (a); processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
Patent MX-PA02007823-A (MX)
Title: Male impotence prosthesis apparatus with wireless energy supply.
Inventor: FORSELL PETER
IPC: A61F5/00
Filed: 2001-02-14
Abstract: A male impotence prosthesis apparatus comprises an operable penile prosthesis (4) implanted in an impotent patient s corpus cavernosum to provide flaccid or erect states of the patient s penis. An energy transmission device (10) for wireless transmission of energy from outside the patient s body to inside the patient s body is provided for use in connection with the operation of the penile prosthesis.
Patent MX-PA02009354-A (MX)
Title: THIEPINO [3,2 b.
Inventor: HENRY JAMES R
IPC: A61P37/08
Filed: 2001-03-08
Abstract: This invention provides novel thiepino[3,2 b]dihydropyridines of the formulae (I, II, V). These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstriction activity. Thus, this invention also provides pharmaceutical compositions, as well as methods, for preventing and treating disorders such as hypersensitivity, allergy, asthma, bronchospasm, dysmenorrhea, esophageal spasm, glaucoma, premature labor, urinary tract disorders, gastrointestinal motility disorders and cardiovascular disorders.
Patent MX-PA02010877-A (MX)
Title: Coated natural leather having low deformation.
Inventor: MENDOZA YERY A
IPC: C14C11/00
Filed: 2001-05-02
Abstract: Coated natural leather, prepared from natural leather having polyurethane coated on its flesh side and having an improved (decreased) measure of deformation, is provided.
Patent MX-PA02011514-A (MX)
Title: The use of plant extracts in a cosmetic composition to protect keratinous fibers.
Inventor: FADEEVA NATALYA
IPC: A61K8/60
Filed: 2001-05-21
Abstract: The present invention provides a method of protecting keratinous fiber from extrinsic damage, e.g., protein loss caused by exposure to heat, chemicals, etc. comprising the application of a composition comprising at least one plant extract. The present invention also contemplates a method of improving combability and or a method of improving curl formation of keratinous fibers. In another embodiment, the present invention is drawn to a composition for the treatment of protection of keratinous fiber comprising willowherb extract.
Patent MX-PA03001182-A (MX)
Title: Use of lipase inhibitors.
Inventor: LENGSFELD HANS
IPC: A61P43/00
Filed: 2001-07-28
Abstract: The present invention relates to the use of lipase inhibitors, for example orlistat, for the manufacture of medicaments for treating, reducing or preventing functional dyspepsia, for example, satiety intensity of the stomach, nausea, inflammation after ingestion of moderate or abundant meals. , especially foods that contain fat or that are rich in fat, and medications thus manufactured
Patent MX-PA03005462-A (MX)
Title: Therapeutic combination of amlodipine and benazepril.
Inventor: WILLIAM LIONEL DALEY
IPC: A61K31/4422
Filed: 2000-12-18
Abstract: The present invention especially relates to the use of a combination comprising  (1) an ACEI selected from the group consisting of benazepril, benazeprilat, and pharmaceutically acceptable salts thereof, and  (2) amlodipine or pharmaceutically acceptable salt thereof,  
for the manufacture a medicament for the treatment or prevention or delay of progression of a condition selected from the group consisting of hypertension, congestive heart failure, angina, myocardial infarction, artherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, blood pressure-related cerebrovasular disease, stroke, pulmonary disease or pulmonary hypertension and headache; 
wherein  (i) the amount of amlodipine or a pharmaceutically acceptable salt thereof corresponds to 6 mg to 40 mg of the free base and  (ii) the amount of the ACE inhibitor or a pharmaceutically thereof corresponds to 20 mg to 160 mg of benazepril hydrochloride.
Patent MX-PA03009107-A (MX)
Title: System for generating pseudorandom sequences.
Inventor: HEPLER EDWARD L
IPC: H04J13/00
Filed: 2002-04-05
Abstract: A pseudorandom code generator comprising a code generator configured to generate a series of 2 M  M-bit wide binary codes starting from a lowest bit to a highest bit; an index code selector configured to select an M-bit wide binary index code corresponding to an index number of a pseudorandom code among a set of pseudorandom codes; a logical operator configured to perform a logical operation between each code generated by the code generator and the index code selected by the index code selector in order to generate a 2 M -bit wide pseudorandom code; and a code reverser configured to reverse an order of bits generated by the code generator from a least significant bit to a most significant bit.
Patent MX-PA04002935-A (MX)
Title: Composting apparatus and method.
Inventor: BRIAN GITT
IPC: C05F9/02
Filed: 2002-09-25
Abstract: Composting apparatuses and composting methods are disclosed. In one embodiment, a composting apparatus includes a housing (60) and a plurality of composting drawers (10) in the housing. The plurality of composting drawers (10) is in a stacked relationship when in the housing, and each drawer includes a bottom region having a plurality of apertures. A plurality of receiving structures (30) is in the housing, and the receiving structures are respectively disposed under the plurality of composting drawers to receive composted material.
Patent MX-PA04003876-A (MX)
Title: Medicament dispenser.
Inventor: HIROTSUGU YASUDA
IPC: A61M15/00
Filed: 2002-10-23
Abstract: A dispenser for dispensing a medicament comprising a canister for housing the medicament and a fluid propellant therefor and a drug-dispensing valve wherein one or more of the internal surfaces of the canister and/or valve comprises a fluorinated coating prepared from plasma polymerisation of one or more fluorinated monomers selected from the group consisting of CH2FCF3 and C3F6 is disclosed. Such a coating provides a highly fluorinated coating which prevents adhesion of drug particles to the internal surfaces of the canister and/or valve.
Patent MX-PA04004205-A (MX)
Title: Method for applying or repairing thermal barrier coatings.
Inventor: CRAIG DOUGLAS YOUNG
IPC: C23C4/00
Filed: 2004-04-30
Abstract: A method applying a thermal barrier coating to a metal substrate, or for repairing a thermal barrier coating previously applied by physical vapor deposition to an underlying aluminide diffusion coating that overlays the metal substrate. The aluminide diffusion coating is treated to make it more receptive to adherence of a plasma spray-applied overlay alloy bond coat layer. An overlay alloy bond coat material is then plasma sprayed on the treated aluminide diffusion coating to form an overlay alloy bond coat layer. A ceramic thermal barrier coating material is plasma sprayed on the overlay alloy bond coat layer to form the thermal barrier coating. In the repair embodiment of this method, the physical vapor deposition-applied thermal barrier coating is initially removed from the underlying aluminide diffusion coating.
Patent MX-PA04005185-A (MX)
Title: Condensed camptothecins as antitumor agents.
Inventor: SATOSHI NIIZUMA
IPC: A61K31/5377
Filed: 2002-11-25
Abstract: The present invention relates to hexacyclic compound of the formula [1], wherein Z, R1, R2, R3 and R4 are as defined in the description and claims and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of cell proliferative disorders.
Patent MX-PA04005245-A (MX)
Title: Package and method for storing and dispensing wet wipes in a pop-up format.
Inventor: MEI-CHIUNG HUANG
IPC: A47K10/32
Filed: 2002-06-13
Abstract: The invention relates to a package (10) and method for storing and dispensing wet wipes in a pop-up format. A group of wet wipes (40) are positioned in a container base (20) between the container base and a pop-up style dispensing partition (24), each wipe in the group of wet wipes having a first visibility index. The container top (22) has a second visibility index and the pop-up style dispensing partition has a third visibility index and the first visibility index is different than the third visibility index such that when the container top (22) is closed the wipe from the group of wet wipes is visibly indicated at the container top as being in-position or not-in-position for pop-up dispensing as soon as the container top (22) is next opened.
Patent MX-PA04007907-A (MX)
Title: Slotted tube with reversible usage for heat exchangers.
Inventor: NICOLAS AVANAN
IPC: F25B39/00
Filed: 2003-03-10
Abstract: The invention relates to metallic slotted tubes (1) having an outer diameter De. The inventive tubes are slotted internally by N helical ribs (2) having an apex angle alpha, height H, base width LN and helix angle beta, said consecutive ribs being separated by means of a slot (3) comprising a flat base of width LR, with a pitch P which is equal to LR + LN. Said tubes are characterised in that: a) De is between 4 and 20 mm, b) the number N of ribs is between 46 and 98, c) the height H of said ribs is between 0.18 mm and 0.4 mm, d) the apex angle alpha is such that 15[masculine ordinal] <= alpha < 30 DEG , and e) the helix angle beta is between 18 DEG and 35 DEG . Said tubes can be used to obtain simultaneously a high heat exchange coefficient in evaporation and condensation and a low pressure drop.