baber/WOPTO huggingface dataset:
Patent CA-2459156-A1 (CA)
Inventor: MCINTYRE DALE FREDERICK
IPC: H04N7/173
Filed: 2004-02-27
Abstract: A method for displaying a motion picture received as a digital data stream and having selectable scene content, by obtaining audience metrics, such as demographic data, and, based on these metrics, selecting replaceable image elements (202) from alternate frame (200) content or from selectable scenes (174a1, 174a2) to be inserted into the image display data stream (180).
Patent CA-2460391-A1 (CA)
Inventor: VARRONE ANTONIO
IPC: B60B21/06
Filed: 2002-09-27
Abstract: L'invention concerne un tampon (10) caractérisé en ce qu'il comprend un élément d'appui (12) et un élément de base. L'élément de base fait saillie d'une surface inférieure de l'élément d'appui (12). Il est proportionné de manière à être logé dans un trou d'accès de rayon (30) d'une jante de roue (34).
Patent CA-2461080-A1 (CA)
Title: Solid-state forms of n-(2-hydroxyacetyl)-5-(4-piperidyl)-4-(4-pyrimidinyl)-3-(4-chlorophenyl)pyrazole
Inventor: ALLEN KIMBERLEY C
IPC: A61P29/00
Filed: 2002-09-25
Abstract: Crystalline forms of the p38 kinase inhibitor N-(2-hydroxyacetyl)-5-(4- piperidyl)-4-(4-pyrimidinyl)-3-(4-chlorophenyl)pyrazole are provided. These crystalline forms include (a) a first anhydrous crystalline form possessing improved physical stability relative to other solid-state forms of the compound; (b) a second anhydrous crystalline form possessing unique properti es relative to other solid-state forms of the compound; (c) a third anhydrous crystalline form possessing unique properties relative to other solid-state forms of the compound; and (d) solvated crystalline forms, hydrated crystalline forms, and crystalline salt forms of the compound that are usefu l, for example, as intermediate solid-state forms in the preparation of other crystalline forms of the compound. Also provided are combinations and pharmaceutical compositions comprising at least one of these crystalline forms, processes for preparing these crystalline forms and for preparing compositions comprising these crystalline forms, and methods for the prophylaxis and/or treatment of a p38 kinase-mediated condition comprising administering to a subject a therapeutically effective amount of at least on e of these crystalline forms.
Patent CA-2461291-A1 (CA)
Title: Inhibition of exoprotein production using aromatic compositions
Inventor: SYVERSON RAE ELLEN
IPC: A61P31/04
Filed: 2002-09-09
Abstract: Absorbent and non-absorbent articles are disclosed. The articles include an effective amount of an aromatic inhibitory compound to substantially inhibit the production of exotoxins by Gram positive bacteria. The aromatic inhibitory compounds of the present invention have the general formula (I), wherein R1 is selected from the group consisting of H, (a), -OR5, -R6C(O)H, -R6OH, -R6COOH, -OR6OH, -OR6COOH, -C(O)NH2, formula (1) and NH2 and salts thereof; R5 is a monovalent saturated or unsaturated aliphatic hydrocarbyl moiety; R6 is a divalent saturated or unsaturated aliphatic hydrocarbyl moiety; R7 is a trivalent saturated or unsaturated aliphatic hydrocarbyl moiety; R8 is a monovalent substituted or unsubstituted saturated or unsaturated aliphatic hydrocarbyl moiety which may or may not be interrupted with hetero atoms; R2, R3, and R4 are independently selected from the group consisting of H, OH, COOH, and -C(O)R9; R9 is hydrogen or a monovalent saturated or unsaturated aliphatic hydrocarbyl moiety.
Patent CA-2462776-A1 (CA)
Title: Protective helmet, such as firefighter's helmet, with inner pads
Inventor: GRILLIOT WILLIAM L
IPC: A42B3/14
Filed: 2004-04-01
Abstract: In a protective helmet comprising a rigid shell having a lower periphery and a suspension system, which may have two crossed straps mounted within the rigid shell, at spaced intervals around a lower periphery of the rigid shell, an array of inflatable pads is carried by the suspension system, within the rigid shell, above the lower periphery. The inflatable pads are joined by and between two fabric sheets. If the suspension system has two crossed straps, as preferred, some of the inflatable pads are disposed directly below the crossed straps, between a central region of the rigid shell and the lower periphery, while another of the inflatable pads is disposed in the central region. The crossed straps may extend through slits in the fabric sheets. The respective pads are inflated with a suitable gas, such as air, with a suitable liquid, such as water, with a suitable foam, or with a suitable gel.
Patent CA-2464366-A1 (CA)
Title: A method for identification and development of therapeutic agents
Inventor: MALLAL SIMON
IPC: C07K14/16
Filed: 2002-10-23
Abstract: The present invention relates generally to the field of identification and determination of bioactive amino acid sequences. In particular, the present invention provides method(s) for determining the influence of variation in host genes on selection of microorganisms with particular amino acid variant s for the purpose of therapeutic drug or vaccine design or individualisation o f such treatment. The invention also provides methods for identifying HLA alle le- specific microorganism sequence polymorphisms that result from HLA restricti on of antigen-specific cellular immune responses. It also provides diagnostic a nd therapeutic methodologies that may be used to measure or treat infection by a microorganism or to prevent infection by the microorganism.
Patent CA-2465119-A1 (CA)
Title: Jante composite de bicyclette a surfaces de freinage sans joint
Inventor: POERTNER JOSHUA R
IPC: B60B5/02
Filed: 2002-11-27
Abstract: L'invention porte sur une jante de bicyclette de plastique renforcée de fibres (FRP) comportant un corps de FRP (12) et un anneau métallique (14) recevant le pneu. Le corps (12) présente une première (20), et une deuxième (22) surface latérale, une surface annulaire (41) extérieure de bord, et une surface annulaire (24) intérieure de bord percée d'au moins deux ouvertures (38) permettant de recevoir et fixer au moins deux rayons (34) au corps (12). L'anneau métallique (14), qui est lié au corps (12) et placé radialement à l'extérieur du corps (12), présente deux surfaces de freinage (52 et 54) sensiblement parallèles et continues.
Patent CA-2465396-A1 (CA)
Inventor: WU XIAOLIN
IPC: C12Q1/68
Filed: 2004-04-20
Abstract: High-throughput methods for mapping integration sites resulting from one or more integrations, such as infection by a retrovirus, are disclosed. The disclosed methods require no selection for specific phenotypes such as antibiotic resistance, and thereby may avoid selection bias. Moreover, the linker-based amplification is simple and rapid, and by using a frequently cutting restriction enzyme, the amplicons are small, which significantly decreases possible amplification and cloning biases.
Patent CA-2465516-A1 (CA)
Title: Reliability metric for a signal parameter estimate
Inventor: STEIN JEREMY M
IPC: H04W64/00
Filed: 2002-11-01
Abstract: A method of producing a reliability metric for a parameter estimate derived from a signal using correlation analysis is described. The method begins by obtaining an indication of whether a non line of sight signal condition is present or likely. Responsive to one or both of these indications, the method derives a reliability metric for the parameter estimate. In one embodiment, the parameter estimate is an estimate of time of arrival (TOA) of the signal, and the reliability metric is root mean square error (RMSE) of the time of arrival estimate. This embodiment obtains an indication of whether a non line of sight signal condition is present or likely based on a measure of the strength of the correlation function at the peak thereof. The measure of the strength of the correlation function at the peak thereof may be energy per chip divided by total received power (Ec/I0) or may simply be the raw energy of the correlation function at the peak. The RMSE metric which is computed in this embodiment varies inversely with the peak strength of the correlation function.
Patent CA-2468115-A1 (CA)
Inventor: OGLE DAVID MARK
IPC: H04L12/24
Filed: 2000-06-02
Abstract: A method, system, and computer program product for enabling messaging systems to use alternative message delivery mechanisms. In existing instant messaging systems, messages cannot be delivered to an intended recipient unless the recipient is currently logged on to an instant messaging system. According to the present invention, users may register one or more alternative message delivery mechanisms (such as pagers, cell phones, etc.) through which they are available as an alternative to an instant messaging system. Constraints may optionally be added to these registered alternatives, such as specifying a limitation on days of the week and/or hours of the day when a particular alternative may be used. Providing that an alternative messaging mechanism is registered, and any constraints for this alternative are satisfied, in the first preferred embodiment the extended IMS will select a suitable alternative and deliver the message. In a second and third preferred embodiment, the sender of the "instant" message will be informed of the available alternative(s). The sender may then choose to have his message delivered even though the intended receiver is not currently logged on to an instant messaging system. Fourth and fifth embodiments enable a message to be delivered to a recipient using a registered mechanism (that may include an IMS), and provide for determining availability of a selected user. Using these techniques, the real-time awareness of potential message receivers in instant messaging systems is extended.
Patent CA-2468257-A1 (CA)
Title: White reference calibration in a dual digitizer
Inventor: BATCHELDER LEE
IPC: H04N1/04
Filed: 2002-11-26
Abstract: A dual digitizer (100) for digitizing both transparent and reflective data mediums is provided where light from the reflective illuminator (130) reflects off the transparent illuminator when the transparent illuminator (110) is off to provide a white reference signal for use in calibrating the dual digitizer.  A method of calibrating a dual digitizer for reflective scans includes:  digitizing a transparent data medium; calibrating the dual digitizer to establish a white reference signal, the calibrating step including generating a light beam, reflecting a first portion of the light beam off a transparent illuminator, and utilizing the first portion of said light beam to establish the white reference signal; and digitizing a reflective data medium. The dual digitizer may be used in medical applications to digitize a transparent data medium such as an X-ray film.
Patent CA-2471490-A1 (CA)
Title: Herbal composition for treating various disorders including psoriasis, a process for preparation thereof and method for treatment of such disorders
Inventor: SARAF DINESH BALAKRISHNA
IPC: A61P11/06
Filed: 2003-01-10
Abstract: The invention provides a novel herbal composition containing the extracts of the leaves and/or stem of Argemone mexicana plant, optionally containing the extracts of the fruits of Cuminum cyminum, which exhibits useful in vitro, in vivo and interesting immunological and pharmacological activities; a process for preparation thereof; and a method of treatment of psoriasis and related immunological and biological disorders by administration of the said novel herbal composition. The useful in vitro, in vivo and interesting immunological and pharmacological activities exhibited by the extracts and fractions of the leaves and/or stem of Argemone mexicana plant include immunosuppression, lymphoproliferation inhibition, cytokine modulation such as IL-2 inhibition, IFNgamma inhibition, IL-10 induction, keratinocyte proliferation inhibition, keratolytic activity, endothelial cell proliferation inhibition, inhibition of cell adhesion molecule expression such as ICAM-1, NEST inhibition, and enzymes inhibition such as p60src Tyrosine kinase, which are known to be involved in anti-psoriatic activity. The novel herbal composition(s) is useful in the treatment of various disorders, such as psoriasis including plaque psoriasis, gutatte psoriasis, pustular psoriasis and psoriasis of the nails; dermatitis and scleroderma; eczema; inflammatory disorders and other autoimmune diseases like psoriatic arthritis, rheumatoid arthritis, Crohn's disease, multiple sclerosis, irritable bowel disease, ankylosing spondilitis, systemic lupus erythremetosus and Sjogren's syndrome; allergies like asthma and chronic obstructive pulmonary disease and is safe, well-tolerated, non-toxic, with minimal and reversible adverse reactions or side effects, and most importantly, with minimal relapse or recurrence of the disease following completion of a treatment regimen. The invention also describes the presence of phosphodiesterase (III, IV and V) inhibition and 5-Lipoxygenase inhibition in the aqueous, ethanolic or aqueous-ethanolic extracts of fruits of Cuminum cyminum plant.
Patent CA-2474091-A1 (CA)
Inventor: KIMURA NAOKI
IPC: C12Q1/68
Filed: 2003-01-31
Abstract: Selon l'invention, un acide nucléique est fixé sur un support constitué de résine synthétique (du polycarbonate, du polyméthyle méthacrylate, un copolymère acrylonitrile-butadiène-styrène, du polyéthylène, du polyéthylène téréphthalate, du polyphénol, du polystyrène, du polyacrylonitrile, du chlorure de polyvinyle ou de l'aramide). Le procédé selon l'invention consiste à déposer sur ledit support une solution formée à partir dudit acide nucléique; à sécher ladite solution; puis à irradier le support au moyen de rayons UV présentant une composante de longueur d'onde de 280 nm, de préférence à une dose supérieure ou égale à 100 mJ/cm?2¿.
Patent CA-2474512-A1 (CA)
Inventor: SWEET LAUREL
IPC: A61P37/02
Filed: 2003-03-21
Abstract: The present invention relates to a method for preparing pseudo islets. In addition, the invention is also directed to methods of treating diabetes and diabetes-related disorders by administering compounds identified by the methods described herein.
Patent CA-2478400-A1 (CA)
Inventor: IFERGAN THIERRY
IPC: G02C9/02
Filed: 2003-03-24
Abstract: Eyeglasses comprise a primary frame and an auxiliary frame detachably secured to the primary frame by interaction of magnetic members on the frames. The frames and magnetic members are configured to maintain the frames in a first orientation in which the auxiliary frame overlies the primary frame and a second orientation in which the auxiliary frame is disposed above and away from the optical axis of lenses carried in the primary frame.
Patent CA-2482838-A1 (CA)
Inventor: SATO NOBUAKI
IPC: A61K31/4162
Filed: 2003-05-29
Abstract: A novel compound having excellent JNK inhibitory activity. It is a compound represented by the following general formula or a salt thereof. (I) In the formula, R1 represents -(CO)h-(NRa)j-(CRb=CRc)k-Ar (wherein Ra, Rb, and Rc each independently represents hydrogen, halogeno, hydroxy, optionally substituted C1-6 alkyl, etc.); Cy means a 5- or 6-membered aromatic heterocycle; and V's each independently means -L-X-Y ~wherein L means a sing le bond, optionally substituted C1-6 alkylene, etc.; X means a single bond, -A- (wherein A represents NR2, O, CO, S, SO, or SO2), etc.; and Y means hydrogen , halogeno, nitro, etc.~.
Patent CA-2483421-A1 (CA)
Title: Yo-yo comportant un systeme actif d'engagement de filin en forme d'etoile rayonnante
Inventor: VAN DAN ELZEN HANS W
IPC: A63H1/30
Filed: 2003-09-08
Abstract: La présente invention a trait à un yo-yo utilisant un système actif d'engagement de filin en forme d'étoile rayonnante disposé dans un ou dans les deux éléments latéraux du yo-yo (2). Le système utilise un réseau de forme d'étoile rayonnante de nervures d'engagement mobiles (58) faisant face au filin (6) et situés à proximité de la structure d'essieu du yo-yo (4). Chaque nervure est indépendamment mobile et est situé à l'extrémité d'un doigt flexible (64) qui permet à la nervure d'être déplacée par le filin en une direction sensiblement parallèle à l'axe de rotation du yo-yo.
Patent CA-2484155-A1 (CA)
Inventor: MERTENS KOENRAAD
IPC: A61P7/04
Filed: 2003-04-28
Abstract: The present invention concerns the use of peptides derived from and antibodi es generated against Factor VIII and the inhibition of Factor VIII interaction with LRP. Furthermore, the present invention concerns a method to inhibit LR P interaction with Factor VIII as well as a method to decrease Factor VIII degradation and/or prolong Factor VIII half-life in a biological fluid and/or a method to treat patients suffering from a blood coagulation disorder, especially Haemophilia A. The present invention also concerns a pharmaceutic al composition useful for the decrease of Factor VIII degradation in a biologic al fluid, the inhibition of Factor VIII interaction with LRP, and/or the prolongation of Factor Vlll half-life in a biological fluid for treatment of a blood coagulation disorder, especially Haemophilia A.
Patent CA-2485851-A1 (CA)
Title: System for molding corrugated pipe
Inventor: CYPHERT DAVID L
IPC: B29C47/08
Filed: 2004-10-25
Abstract: Carriage assembly mounted molds are paired along a production system axis at a receiving region. Each carriage assembly is configured with an axially inwardly depending threaded connector nut configured to engage a translational screw moving the mold sets in registry about an extrusion die to establish a dynamic forming tunnel. Each mold of a mold set is configured having an internal mold cavity with mold crests spaced apart to define a sequence of vacuum support regions. A sequence of annular insert components are positioned over the vacuum support regions to form mold cavities and to define vacuum cavities.
Patent CA-2486619-A1 (CA)
Title: Methodes et produits permettant de traiter des etats inflammatoires
Inventor: SCARISBRICK ISOBEL A
IPC: C12Q1/68
Filed: 2003-05-21
Abstract: Cette invention a trait à des méthodes ainsi qu'à des nécessaires permettant de traiter des états inflammatoires, lesquelles méthodes reposent sur la modulation de l'activité de la kallikréine 6 protéase.
Patent CA-2486889-A1 (CA)
Inventor: ZIELINSKI KEITH T
IPC: C09D7/65
Filed: 2003-06-12
Abstract: A coating composition having polyvinyl chloride extender particles with an average particle size in a range from about 5 to about 150 microns, wherein the coating composition is free of plasticizers, and the particles remain as discrete particles in the film after the coating is allowed to cure or air dry.
Patent CA-2487189-A1 (CA)
Inventor: SHARMA ABHISHEK
IPC: H04L12/56
Filed: 2003-06-11
Abstract: A system and methods are shown for providing packet data serving node (PDSN) load balancing and fault tolerance. One exemplary method includes providing an access node (280) with a plurality of packet data serving nodes (218A, 220) and at least one system manager (222), receiving from a radio node (206) on a first packet data serving node (218) a registration request, determining that the first packet data serving node (218A) is unable to serve the registration request, and sending a packet data serving node selection request from the first packet serving node (218A) to the system manager (222), determining a second packet data serving node (220) to serve the registration request and providing an address of the second packet data serving node (220) to the first packet data serving node (218A), and sending a registration reply message from the first packet data serving node (218A)to the radio node (206), where the registration reply message includes the address of the second packet data serving node (220).
Patent CA-2492492-A1 (CA)
Inventor: MARTIN MURRAY D
IPC: G07B17/00
Filed: 2003-07-18
Abstract: A closed loop postage metering system includes networked meters that provide mailers and/or recipients the capability to request additional or modified services during processing of a mail piece by a carrier. The networked meter allows the Post to charge the mailer, or even the recipient for these services or to provide them with a refund or credit. The services can include changing the processing of the mail piece. Further, the closed loop postage metering system enables more precise methods of paying for services when multiple carriers handle a mail piece. A special case of such multiple carriers handling is the handling of international mail.
Patent CA-2493645-A1 (CA)
Inventor: HABER BERND
IPC: A23L1/30
Filed: 2003-07-15
Abstract: L'invention concerne des agents hypocholestérolémiants constitués de fibres alimentaires et d'au moins un principe actif hypocholestérolémiant. L'invention concerne également un procédé pour la production de tels agents hypocholestérolémiants, ainsi que leur utilisation.
Patent CA-2494014-A1 (CA)
Title: Monocyclic derivatives as matrix metalloproteinase inhibitors
Inventor: PICARD JOSEPH ARMAND
IPC: A61P9/00
Filed: 2003-08-03
Abstract: This invention provides compounds defined by Formula (I) or a pharmaceutically acceptable salt thereof, wherein R', Q, D, V', m, and R2 are as defined in the specification. The invention also provides pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, as defined in the specification, together with a pharmaceutically acceptable carrier, diluent, or excipient. The invention also provides methods of inhibiting an MMP-13 enzyme in an animal, comprising administering to the animal a compound of Formula (I), or a pharmaceutically acceptable salt thereof. The invention also provides methods of treating a disease mediated by an MMP-13 enzyme in a patient, comprising administering to the patient a compound of Formula (I), or a pharmaceutically acceptable salt thereof, either alone or in a pharmaceutical composition. The invention also provides methods of treating diseases such as heart disease, multiple sclerosis, osteo- and rheumatoid arthritis, arthritis other than osteo- or rheumatoid arthritis, cardiac insufficiency, inflammatory bowel disease, heart failure, age-related macular degeneration, chronic obstructive pulmonary disease, asthma, periodontal diseases, psoriasis, atherosclerosis, and osteoporosis in a patient, comprising administering to the patient a compound of Formula (I), or a pharmaceutically acceptable salt thereof, either alone or in a pharmaceutical composition. The invention also provides combinations, comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, together with another pharmaceutically active component as described in the specification.
Patent CA-2495732-A1 (CA)
Inventor: HOUSTON DONALD J
IPC: C06B31/28
Filed: 2005-02-01
Abstract: A pumpable watergel explosive composition comprises 10 to 40 wt %, based on the total weight of the pumpable explosive composition, of a continuous liquid phase comprising a solvent, a solubilized chemical sensitizer and a gelling agent and 60 to 90 wt %, based on the total weight of the pumpable explosive composition, of a discontinuous solid phase comprising particulate oxidizer salt particles having interstitial spaces between the salt particles.  The watergel explosive composition has a density of 1.05 - 1.4 g/cc and, a shear thinning rheology such that, when subjected to an external force, the explosive composition has a viscosity sufficiently low to render the watergel explosive composition pumpable. The combination of density and low water content provides energy numbers normally associated with more expensive aluminized formulations.
Patent CA-2495967-A1 (CA)
Title: Nouveau procede de synthese et nouvelle forme cristalline de l'agomelatine ainsi que les compositions pharmaceutiques qui la contiennent
Inventor: SOUVIE JEAN-CLAUDE
IPC: A61P25/16
Filed: 2005-02-03
Abstract: Procédé de synthèse industrielle et forme cristalline II du composé de formu le (I) (voir formule I)
Patent CA-2496362-A1 (CA)
Title: Analogues of vitamin d
Inventor: JOMARD ANDRE
IPC: A61K8/67
Filed: 2003-08-25
Abstract: The invention relates, as new and useful industrial products, to biaromatic compounds, which are analogues of vitamin D, of general formula (I): Q,A~R 2 R4 R~ R 4 T~B OH (I) HO and to their method of preparation and to their use in pharmaceutical compositions intended for use in human or veterinary medicine , or alternatively in cosmetic compositions.