baber/WOPTO huggingface dataset:
Patent ES-2296742-T3 (ES)
Title: Inhibidores de caspasa de tipo carbamato y sus usos.
Inventor: BEBBINGTON DAVID
IPC: A61K31/473
Filed: 2001-03-29
Granted: 2008-05-01
Abstract: Un compuesto de fórmula I:** ver fórmula** o una sal farmacéuticamente aceptable del mismo, en la cual: Z es oxígeno o azufre; R1 es hidrógeno, -CHN2, R, -CH2OR, -CH2SR o -CH2Y; R es un grupo alifático C1-12, arilo, aralquilo, heterociclilo o heterociclilalquilo; Y es un grupo lábil electronegativo seleccionado entre F, Cl, Br, I, arilo y grupos alquilsulfoniloxi, trifluorometanosulfoniloxi, OR'''', SR'''', -OC=O(R'''') o -OPO(R6)(R7), en los que R'''' es un grupo alifático, un grupo arilo, un grupo aralquilo, un grupo carbocíclico, un grupo alquil-carbocíclico, un grupo heterocíclico o un grupo alquil-heterocíclico; en el que R6 y R7 se seleccionan independientemente entre R'''' o OR''''; R2 es CO2H, CH2CO2H o sus ésteres o amidas o CONHSO2-(alquilo); R3 se selecciona entre H, una cadena lateral de un alfa-aminoácido natural o un grupo sustituido o sin sustituir que tiene un peso molecular hasta 140 daltones seleccionado entre un grupo alifático, arilo, aralquilo o un anillo heterocíclico o heterocicloalquilo en el que el quedicho anillo heterocíclico o de heterocicloalquilo es un sistema de anillos monocíclico o policíclico saturado o insaturado de tres a nueve miembros en el que cada anillo contiene hasta tres heteroátomos seleccionados entre O, N o S; y R4 y R5 tomados conjuntamente con el átomo de nitrógeno que interviene forman un sistema de anillos heterocíclicos mono-, bi- o tri-cíclico que tiene 1-6 heteroátomos seleccionados entre nitrógeno, oxígeno o azufre.
Patent ES-2271011-T3 (ES)
Title: Un metodo y un aparato para la recuperacion de metales.
Inventor: GRIPENBERG HENRIK
IPC: C22B7/00
Filed: 2001-05-03
Granted: 2007-04-16
Abstract: Un método para la recuperación de metales a par- tir de una materia prima consistente, esencialmente, en finos metálicos, polvos o polvo con un diámetro de partí- culas inferior a 5 milímetros, que comprende las opera- ciones siguientes: a) suministrar dicha materia prima (50) a una llama (25) de un quemador (20) de oxicombustible, b) hacer que dicha materia prima se aglomere fundiendo parcialmente la superficie de las partículas por me- dio de calor procedente de dicha llama (25), sin cambiar esencialmente su composición química, pro- porcionando por tanto un producto aglomerado (60) esencialmente metálico, y c) recuperar dicho producto aglomerado (60).
Patent ES-2311519-T3 (ES)
Inventor: DUSSAUZE JACQUES
IPC: B01D15/08
Filed: 2001-05-23
Granted: 2009-02-16
Abstract: An installation for the automatic preparation of specimens by liquid/solid extraction on a column is characterized in that the extraction device comprises, on either side of the columns (3), a valve (4) controllable to switch one column (3) to the other to actuate one column (3) adapted to ensure the extraction function when another column (3) is in a non-operating condition, each switching valve (4) being connected to a controllable common direction reversing valve (5) arranged to impose one direction of circulation on the fluid in anyone of the columns (3) of the extraction device and to ensure its return to the valve (5) to distribute the treated fluid toward a circuit selectively either for its rejection or for its analysis.
Patent ES-2234855-T3 (ES)
Inventor: MEIER JAMES R
IPC: B65H1/28
Filed: 2001-06-26
Granted: 2005-07-01
Abstract: A card printer has a card feed hopper assembly that will support stacks of two different size cards in hopper sections. The card feed hopper assembly is movable transversely of the printer to position the respective hopper sections to be aligned with a card feed path on the printer, and then positioned so that cards in the hopper section aligned with the card feed path will be driven into the printer. The hopper is lifted when it is moved transversely, and then lowered down to provide the card drive for cards in the hopper section that is aligned with the card feed path.
Patent ES-2250473-T3 (ES)
Inventor: MATHEA HANS
IPC: G03G15/043
Filed: 2001-08-24
Granted: 2006-04-16
Abstract: In a printer with an electrically chargeable image drum, such as a laser or a LED printer, for imprinting a medium by transferring toner to the medium, including, arranged around the image drum, a charging unit, a writing unit and a toner unit, the toner unit is disposed at a predetermined angular distance from the charging unit and a sensor is disposed at essentially the same angular distance from the charging unit to determine the charge of the image unit at the toner location for adjusting the voltage of at least one of the charging unit and the toner unit depending on the charge voltage of the image drum as determined by the sensor.
Patent ES-2284711-T3 (ES)
Inventor: COLLINS STEPHEN D
IPC: A61K31/4436
Filed: 2001-10-19
Granted: 2007-11-16
Abstract: (R)-N-[4,4-Bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid and salts thereof are effective GABA uptake inhibitory compounds and exert pharmacological effects on pain associated with diabetic neuropathy and migraine.
Patent ES-2267852-T3 (ES)
Inventor: IZUCHUKWU JOHN I
IPC: B29C48/09
Filed: 2001-11-01
Granted: 2007-03-16
Abstract: An apparatus for forming a polymeric pressure vessel has an outer tube extruder for driving a fluid polymeric material and forming the fluid polymeric material into an outer tubular member; a variable die located downstream of the outer tube extruder and constructed and arranged to alternately increase and decrease in size to thereby alternately increase and decrease the thickness of the wall of the outer tubular member; and a molding apparatus located downstream of the variable die and constructed and arranged to expand spaced-apart portions of the outer tubular member having greater wall thickness into hollow chambers to thereby form a plurality of serially interconnected hollow chambers.
Patent ES-2286162-T3 (ES)
Title: Compuesto lactama.
Inventor: KOENIG THOMAS MITCHELL
IPC: A61K31/55
Filed: 2001-11-02
Granted: 2007-12-01
Abstract: (N)-((S)-2-hidroxi-3-metil-butiril)-1-(L-alaninil)-(S)-1-amino-3-metil-2, 3, 4, 5-tetrahidro-1H-3-benzacepin-2-ona dihidrato :
Patent ES-2290206-T3 (ES)
Inventor: NAGLER NORBERT
IPC: B65D90/02
Filed: 2002-02-15
Granted: 2008-02-16
Abstract: A storage container for water-endangering liquids comprises a leakage detection and restraint system. The storage container provides a container that allows for a short-notice alarm system and that minimizes the collection volume, that is to ensure that the water-endangering liquid spreads as little as possible, as well as to reduce construction and maintenance costs. The storage container is characterized by the following features: a gutter (4) surrounding the tank (13) that is directly contiguous with the outer wall (2) of the storage container and that collects leaked liquid, at least one gutter outlet (14), at least one liquid collection container (6), and at least one detection system (12) for the water-endangering liquids. The gutter outlet (14) is adapted to guide the liquid collected in the gutter (4) to the liquid collection container (6) that is provided with the detection system (12).
Patent ES-2315330-T3 (ES)
Inventor: DWORSCHAK MANFRED
IPC: A61B17/322
Filed: 2002-07-01
Granted: 2009-04-01
Abstract: Surgical knife comprises a blade holder (12) and a blade (14) made of fiber-reinforced plastic material. Preferred Features: The plastic material is a fiber-reinforced thermoplastic. The plastic material is reinforced with glass fibers or carbon fibers. The fiber content is 25-70, preferably 40-60%. The blade is arranged in one piece on the blade holder which is arranged in one piece on a handle (24).
Patent ES-2253515-T3 (ES)
Inventor: BONACCINI DOMENICO
IPC: H01S3/30
Filed: 2002-03-07
Granted: 2006-06-01
Abstract: A fibre laser comprises a fibre light guide (3) having an active medium, a laser as pumping source (1) and a first pair of Bragg gratings (6, 8) forming a first resonator (4). The first pair of Bragg gratings (6, 8) resonates the pump laser (1) and there is provided a second pair of Bragg gratings (7, 9) resonating at the output wavelength of the fibre laser. <IMAGE>
Patent ES-2225772-T3 (ES)
Inventor: CHRISTENSEN JOHN
IPC: A61L29/10
Filed: 2002-02-12
Granted: 2005-03-16
Abstract: An implant and a process of modifying an implant surface, which implant is in particular a hip implant, a tooth implant, a bone screw, fixation pin or a fixation nail (pin-fixation), comprising a metallic base body, which implant has a surface modified by a material containing a tissue-friendly metal, such as tantalum or niobium, for the formation of a surface modification where at least the tissue-friendly metal is alloyed with the surface and constitutes a uniform, diffusion-tight outer zone on the body, which outer zone has a higher ductility than the metallic base body in order to obtain a tissue-friendly implant with increased fatigue strength.
Patent ES-2272711-T3 (ES)
Inventor: SULLIVAN ALICE C
IPC: C07F7/28
Filed: 2002-01-09
Granted: 2007-05-01
Abstract: The invention relates to new compounds of the formula, wherein R and R1 are each independently hydrogen, a linear or branched C1-40 alkyl, C2-40 alkenyl or C2-40 alkynyl group, an aryl or C1-40 alkylaryl group or an optionally complex metal ion Mn+/n wherein n is an integer from 1 to 8; the free valences of the silicate oxygen atoms are saturated by one or more of: silicon atoms of other groups of the formula, hydrogen, a linear or branched C1-12 alkyl group or by cross-linking bridge members R3qM1(OR2)mOk/2 or Al(OR2)3-pOp/2 or R3 Al(OR−)2-1 O1/2; wherein M1 is Si or Ti; R2 is linear or branched C1-12 alkyl group; and R3 is alinear or branched C1-6 alkyl group; k is an integer from 1 to 4 and q and m are integers from 0 to 2; such that M+k+q=4; and p is an integer from 1 to 3; and r is an integer from 1 to 2; or other known oxo metal bridging systems; x, y and z are integers such that the radio of x:y+z, varies from 0.00001 to 100,000 with the fragments [O3/2SiCH(CH2PO(OR)(OR1))CH2CH2SiO3/2]x and [O3/2SiCH2CH2PO(OR)(OR1)]y always present whilst the integer z varies from 0 to 200y. The compounds are useful as catalysts for a wide variety of reactions and have the advantages that they can be prepared in a one-pot reaction and functional group losding can be tailored to be at a required level. In addition, the compounds have high chemical and thermal stability, fixed and rigid structures, are insoluble in organic solvents, high resistance to ageing, and can easily be purified and reused.
Patent ES-2291473-T3 (ES)
Inventor: ITO SHUZO
IPC: C21B13/10
Filed: 2002-06-13
Granted: 2008-03-01
Abstract: In producing a granular metal, a raw material containing a metal oxide and a carbonaceous reducing agent is heated to reduce the metal oxide in the raw material, and the formed metal is further molten by heating and then is coagulated while separating it from the slag by-produced. The raw material further comprises a coagulation accelerator for the by-produced slug. Allows the production of a granular metal having a high metal purity which has a large scale granule diameter, resulting in excellent transportability and handleability, in high yield with good productivity.
Patent ES-2566561-T3 (ES)
Title: Producción in vivo de ARN pequeños de interferencia que median el silenciamiento génico
Inventor: ZAMORE PHILLIP
IPC: C12N5/00
Filed: 2002-07-12
Granted: 2016-04-13
Abstract: Un método no terapéutico de inducción de interferencia de ácido ribonucleico (ARNi) de un gen objetivo en una célula, utilizando un molécula de ácido nucleico aislado que comprende una secuencia reguladora operativamente enlazada a una secuencia de ácido nucleico que codifica un precursor de ácido ribonucleico (ARN) manipulado genéticamente, en donde el precursor comprende (i) una primera porción de tallo que comprende una secuencia de 18 a 30 nucleótidos que es totalmente complementaria a una secuencia de un ARN mensajero (ARNm) del gen objetivo; (ii) una segunda porción de tallo que comprende una secuencia de 18 a 30 nucleótidos que es suficientemente complementaria a la primera parte de tallo para hibridar con la primera porción de tallo para formar un tallo dúplex; y (iii) una porción de bucle de 4 a 20 nucleótidos que conecta las dos porciones de tallo.
Patent ES-2351436-T3 (ES)
Inventor: JOHNSTONE CRAIG
IPC: A61K31/407
Filed: 2002-07-19
Granted: 2011-02-04
Abstract: The invention relates to thiophene carboxamides of formula (I), wherein A, R1, R2, R3, n and X are as defined in the specification, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.
Patent ES-2302827-T3 (ES)
Inventor: TANGHOJ ALLAN
IPC: A61M25/16
Filed: 2002-06-28
Granted: 2008-08-01
Abstract: The present invention is a catheter assembly allowing for non-contaminated insertion of a catheter into a urinarycanal. The assembly includes a package for the catheter and an applicator to be used for guiding the catheter into the urinary canal without touching the catheter by holding the catheter via walls of the applicator. The assembly further comprises clamping means for pressing the walls of the applicator into engagement with the catheter. The present invention further relates to an applicator with integrated clamping means to be used with the assembly.
Patent ES-2254753-T3 (ES)
Inventor: BAREZZANI GUALTIERO
IPC: H01R4/40
Filed: 2002-11-11
Granted: 2006-06-16
Abstract: A connector for joining together opposed ends of two sections of wire of a catenary comprises a body having two parts 1,2 arranged to be clamped together with the opposed ends of the sections between them, the underside of the body being formed to provide a surface 20 which extends between the undersides of the wire sections to provide a continuous, smooth transition between them. The surface 20 may extend from one end thereof which is flush with the underside of one of the wire sections, at an inclination to the underside of the other section, or the surface may have two longitudinal sections 20a,20b extending in opposite directions from an intermediate part 20c of the surface each at an inclination to the underside of a respective wire section.
Patent ES-2276967-T3 (ES)
Inventor: LARSEN ALLAN R
IPC: E05B83/10
Filed: 2002-12-10
Granted: 2007-07-01
Abstract: A locking arrangement serving for locking a door hinged on a casing on e.g. a container by a combination or key lock. The locking arrangement comprises a rotatable closing rod for keeping the door closed by engaging the casing in a closed position; a fitting having a U-shaped part encompassing at least a length of the closing rod; two flushing locking holes made with one hole in each of the opposite walls of the U-shaped part; a transverse hole made in the closing rod and flushing with the locking holes in the closed position; and a bolt having a first section provided with a head, and a second section displaceably mounted in the lock between a locked inner position and an unlocked outer position; whereby the locking arrangement is locked when the bolt is extending through the transverse hole and the locking holes in locked inner position. The first section of the bolt is a separate part for detachably being assembled to its second section, whereby the locking arrangement continuously can function with a bolt head acting as seal without risk of the locking mechanism of the lock thereby being damaged or ruined by impurities or moisture.
Patent ES-2282514-T3 (ES)
Title: Piperidin-2,6-dionas sustituidas de forma heterociclica en la posicion3.
Inventor: BUSCHMANN HELMUT HEINRICH
IPC: A61P35/00
Filed: 2002-12-18
Granted: 2007-10-16
Abstract: Piperidin-2, 6-dionas sustituidas de forma heterocíclica en la posición 3 de fórmula general I donde R1 y R2 iguales o diferentes, significan H, Br, Cl, F, CF3, OH, NO2, NH2, N(CH3)2, alquilo(C1-3), alcoxi(C1-3), fenilo, o forman juntos un anillo bencénico condensado, estando los anillos sustituidos, en caso dado, con R1 y/o R2 y teniendo R1 y R2 los significados arriba definidos; R3 significa H, un grupo metilo o, si hay un enlace simple C-N, representa OH, alcoxi(C1-3) o un grupo [O(CO)alquilo(C1-3)], o junto con el átomo de C representa un grupo carbonilo; R4 significa H, F, CF3 o alquilo(C1-3); R5 representa H, un grupo CH2-OH o un grupo CH2-NR6R7, donde R6 y R7 son iguales o diferentes y significan un grupo alquilo de 1 a 6 átomos de C (de cadena lineal o ramificado) o junto con el átomo de N representan un anillo pirrolidina, piperidina, hexametilenimina o morfolina; n es igual a 0 ó 1;
Patent ES-2240852-T3 (ES)
Inventor: BAKER DAVID SCOTT
IPC: C07C41/03
Filed: 2002-11-19
Granted: 2005-10-16
Abstract: A process for the epoxidation of an olefin, which process comprises reacting a feed comprising the olefin, oxygen and a reaction modifier in the presence of a highly selective silver-based catalyst at a reaction temperature T, and with the reaction modifier being present in a relative quantity Q which is the ratio of an effective molar quantity of active species of the reaction modifier present in the feed to an effective molar quantity of hydrocarbons present in the feed, and which process comprises the steps of: operating at a first operating phase wherein the value of T is T1 and the value of Q is Q1, and subsequently operating at a second operating phase at a reaction temperature which is different from the reaction temperature employed in the first operating phase, such that the value of T is T2 and the value of Q is Q2, whereby Q2 is determined by calculation and Q2 is defined by the formula Q2 = Q1 + B (T2 - T1), wherein B denotes a constant factor which is greater than 0; a reaction system suitable for performing the process for the epoxidation of an olefin; a computer program product which comprises a computer readable program recorded on a computer readable medium, suitable for instructing a data processing system of a computer system to execute calculations for the process for the epoxidation of an olefin; and a computer system which comprises the computer program product and a data processing system.
Patent ES-2268182-T3 (ES)
Inventor: BLUMBERG RICHARD S
IPC: A01N63/00
Filed: 1996-01-17
Granted: 2007-03-16
Abstract: Methods and products for modulating an immune response are provided. Pharmaceutical preparations contain a conjugate of an antigen and an FcRn binding partner. The conjugates are administered to mammals in effective amounts to modulate the immune system by stimulating the immune response against the antigen or tolerizing the immune system to the antigen. The antigen may be characteristic of a pathogen, of an autoimmune disease, of an allergen or of a tumor.
Patent ES-2276991-T3 (ES)
Inventor: HERWIG JURGEN
IPC: C07C5/05
Filed: 2003-03-08
Granted: 2007-07-01
Abstract: A method for the production of cyclododecene (CDEN) by selective gas-phase hydrogenation of cyclododecatriene (CDT) and/or cyclododecadiene (CDD) involves using a solid-bed reactor in which the bed number (Bo) is more than 100 (Bo = product of average flow rate and length of flow tube divided by axial diffusion coefficient).
Patent ES-2266712-T3 (ES)
Title: Modulo de airbag.
Inventor: HELMSTETTER MATTHIAS
IPC: B60R21/20
Filed: 2003-12-18
Granted: 2007-03-01
Abstract: Módulo de airbag para un sistema de retención de ocupantes de vehículos, donde el módulo del airbag (10) lleva un soporte de generador de gas (14) con un fondo (16) y una pared periférica (18), así como una tapa de recubrimiento (24) con una pared lateral (30) que se extiende desde una pared anterior (26) de la tapa de recubrimiento (24), y donde en el borde de la pared lateral (30) alejado de la pared anterior (26) están conformados unos ganchos de retención (32), caracterizado porque los ganchos de retención (32) encajan en los correspondientes orificios de retención (34) en el fondo (16) del soporte del generador de gas (14), y porque en el fondo (16) están conformados unos elementos elásticos (36) que en el estado montado del módulo del airbag (10) mantienen en posición los ganchos de retención (32).
Patent ES-2261882-T3 (ES)
Title: Aparato de formacion de imagenes y procedimiento de tratamiento de impresion.
Inventor: OHISHI TSUTOMU
IPC: H04N1/32
Filed: 2003-09-12
Granted: 2006-11-16
Abstract: Un aparato de formación de imágenes (100) que comprende: una parte que facilita información (302) que funciona como un servidor web, facilitando la parte que facilita información a un terminal cliente, datos de pantalla que se van a visualizar como una pantalla web por medio de un navegador web del terminal cliente, usándose los datos de pantalla para seleccionar uno o más aparatos de formación de imágenes entre una pluralidad de aparatos de formación de imágenes conectados a una red, y una parte de petición de impresión (301) para distribuir datos de impresión y una petición de impresión a uno o más aparatos de formación de imágenes seleccionados en la pantalla web.
Patent ES-2237741-T3 (ES)
Title: Valvula para recipiente presurizado y recipiente asi equipado.
Inventor: YQUEL JEAN-PIERRE
IPC: B65D83/14
Filed: 2003-08-28
Granted: 2005-08-01
Abstract: Válvula para recipiente presurizado que comprende: - un orificio (21; 44; 55; 65) configurado para ser atravesado por un fluido a distribuir, - un obturador (30) móvil bajo la acción de la gravedad entre una posición de obturación tomada cuando la válvula tiene una orientación predeterminada, posición de obturación en la cual el obturador obtura sensiblemente dicho orificio, y una posición de distribución en la cual el obturador libera dicho orificio, caracterizada porque comprende un absorbedor (32) situado corriente abajo del obturador con respecto al sentido de circulación del fluido, apropiado para absorber por lo menos un gas propulsor contenido en el fluido y para liberarlo por lo menos parcialmente cuando la presión en la proximidad del absorbedor resulta suficientemente baja.
Patent ES-2535974-T3 (ES)
Title: Generador de aerosol para la formulación de fármacos
Inventor: NICHOLS WALTER A
IPC: A61M15/00
Filed: 2003-01-15
Granted: 2015-05-19
Abstract: Un generador de aerosol (101) que comprende: una boquilla (105) que tiene una salida a través de la cual se puede suministrar aerosol a un usuario del generador de aerosol; un paso de aire (110a) a través del cual se puede suministrar aire a un interior de la boquilla (105); un sensor (138) para detectar una caída de presión en el interior de la boquilla (105); y un alojamiento (103), caracterizado porque comprende: un pasaje capilar (102) dispuesto dentro del alojamiento (103); un calentador dispuesto dentro del alojamiento (103); un depósito (118) dispuesto dentro del alojamiento (103); una cámara de dosificación (122) dispuesta dentro del alojamiento (103), en el que a la cámara de dosificación se le puede suministrar fluido desde el depósito (118) por medio de un primer paso de flujo (100a) y al pasaje capilar (102) se le puede suministrar fluido desde la cámara de dosificación (122) por medio de un segundo paso de flujo (100b); una fuente de alimentación (140) adaptada para suministrar energía eléctrica al calentador; una primera válvula (120) adaptada para abrir y cerrar el primer paso de flujo (100a); una segunda válvula (124) adaptada para abrir y cerrar el segundo paso de flujo (100b); una tercera válvula (130) adaptada para abrir y cerrar el paso de aire (110a); y un motor (134) y un árbol de levas (132), el árbol de levas incluye una pluralidad de lóbulos del árbol de levas (132b, d, e) asociados en forma operativa con las válvulas primera (120), segunda (124) y tercera (130), los lóbulos del árbol de levas se pueden operar para cerrar la primera válvula (120) y abrir las válvulas segunda (124) y tercera (130) durante un ciclo de suministro de aerosol en el que se suministra fluido al pasaje capilar (102).