baber/WOPTO huggingface dataset:
Patent EA-007432-B1 (EA)
Title: Method of manufacturing an amorphous form of the hemi-calcium salt of (3r, 5r) 7-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid (atorvastatin)
Inventor: RADL STANISLAV
IPC: C07D207/32
Filed: 2003-01-30
Abstract: A method of manufacturing an amorphous form of the hemi-calcium salt of (3R, 5R) 7-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid of formula (I), in which (3R, 5R) 7-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid or its salt with a cation Mwherein Mis either a cation of an alkali metal or an ammonium cation of formula RNHwherein R is lower C-Calkyl, n may reach values ranging between 0 and 3, is, without isolating the intermediate in the form of the hemi-calcium salt or of another salt, acid or lactone, converted, in a solution, by the treatment with the calcium salt or calcium hydroxide, or a calcium C-Calcoholate, to the hemi-calcium salt, and the latter is precipitated with a C-Chydrocarbon or dialkylether of formula ROR, wherein each of Rand Ris a C-Calkyl group. The starting acid or its salt is prepared starting from (3R, 5R) tert-butyl (6-{2-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]dioxane-4-yl)-acetate of formula II.
Patent EA-006224-B1 (EA)
Title: Ergonomic controls in a surgical lighting system
Inventor: JESURUN DAVID
IPC: F21V21/40
Filed: 2003-02-05
Abstract: A lighting system (10) suited to use in an operating theater includes one or more lightheads, each having a housing (28) and a bezel (50) extending therefrom. A light source (38) is disposed within the housing. A handle (36) extends below the bezel and is rotatable relative thereto. A lighting control input means (60), associated with the bezel allows adjustment of the intensity of light emitted by the light source. A sterile cover (54) can be placed over both the handle and the bevel, allowing the input means to be manipulated by pressure on the cover with the thumb of the operator's hand, while simultaneously grasping the handle in the palm and fingers.
Patent EA-007304-B1 (EA)
Title: Carbon black sampling for particle surface area measurement using laser-induced incandescence and reactor process control based thereon
Inventor: STAGG BARRY JAMES
IPC: G01N21/63
Filed: 2003-07-18
Abstract: Method for in-situ sampling and measuring particulate (e.g., carbon black) fineness in a process stream, such as in a carbon black reactor, comprising (a) sampling particles in-situ from a process stream, (b) adjusting the sample to conditions suitable for 1,11, (c) measuring the fineness using LII, and (d) correlating the LII fineness measurement with actual particle fineness. Method for in-situ sampling a particle-containing stream and measuring particle fineness using laserinduced incandescence (LII) comprising (a) sampling particles in-situ, (b) adjusting the sample to conditions suitable for LII, (c) measuring the adjusted sample using LII, and (d) correlating the LII measurements with actual particle fineness. Also included is a method of sampling and controlling a process based on the real-time, on-line, in-situ methods for sampling and measuring particles. Sampling can comprise drawing a sidestream from a source of the particles. Adjusting the sample to conditions suitable for LII can comprise diluting the sample or bringing the temperature of the sample to ambient conditions. Correlating may comprise using a correlation function determined by comparing LII measurements and laboratory fineness measurements for particle samples drawn at the same time.
Patent EA-008283-B1 (EA)
Title: Integrated process for making acetic acid and methanol
Inventor: THIEBAUT DANIEL MARCEL
IPC: C07C29/151
Filed: 2003-05-20
Abstract: The present invention provides a plant and a process that produces both methanol and acetic acid under substantially stoichiometric conditions, wherein an unadjusted syngas having an R ratio less than 2.0 is provided. All or part of the unadjusted syngas is supplied to a separator unit to recover CO, CO and hydrogen. At least a portion of any one or combination of the recovered CO, CO and hydrogen is added to any remaining syngas not so treated or alternatively combines in the absence of any remaining unadjusted syngas to yield an adjusted syngas with an R ratio of 2.0 to 2.9 which is used to produce methanol. Any recovered COnot used to adjust the R ratio of the unadjusted syngas can be supplied to the reformer to enhance CO production. At least a portion of the recovered CO is reacted in the acetic acid reactor with at least a portion of the produced methanol to produce acetic acid or an acetic acid precursor by a conventional process.
Patent EA-009101-B1 (EA)
Title: Probing method for a multi-station network
Inventor: LARSEN JAMES DAVID
IPC: H04L12/28
Filed: 2004-12-14
Abstract: The invention relates to a method of operating a communication network, the network comprising a plurality of stations which are able to transmit data to and receive data from one another. The method comprises defining a first probing channel for the transmission of probe signals to other stations. Other stations which receive the first probe signals from a probing station indicate to the probing station their availability as destination or intermediate stations. A neighbor table comprising details of these other available stations is maintained at each station. Also, second probe signals are sent and received from stations in the neighbor table and a gradient table comprising data related to the cost of communicating with each neighbor station is maintained at each station, thereby to allow each station to select a predetermined number of intermediate stations for onward transmission of data from an originating station to a destination station at minimum cost.
Patent EA-013468-B1 (EA)
Title: Immunostimulatory single-stranded ribonucleic acid with phosphodiester backbone
Inventor: BAUER STEFAN
IPC: C12N15/00
Filed: 2006-09-15
Abstract: Immunostimulatory single-stranded oligoribonucleotides (ssORN) with phosphodiester backbones induce TLR7-independent and MyD88-dependent immune activation. These immunostimulatory ssORN are useful to induce a ThI -like immune response in a subject, to induce an antigen-specific immune response in a subject, and to treat a subject having a cancer, an infectious disease, an allergic condition, or asthma.
Patent EA-013490-B1 (EA)
Title: Intraoral instrument for ensuring close fit of dentures
Inventor: NABIEV NURZHAN SADYKHOZHAEVICH
IPC: A61C13/38
Filed: 2008-03-13
Abstract: The invention relates to medicine, namely to orthopaedic dentistry and can be used in technological stages of manufacturing dentures, in implantology at the stages of implantation of the implants and placing the abutments. The task of the invention is creating very simple, cheap and easy to use intraoral instrument enabling easily, simply and accurately to determine the direction of the introduction way of the denture both at the preparatory stage and during dissection of the bearing teeth. The intraoral instrument for ensuring close fit of the dentures contains a chamber made of the transparent material in the form of a sphere or a truncated sphere and filled with liquid to form an air bubble 0.1-2 mm in diameter. In the particular case of the instrument implementation, for example when dealing with the upper jaw of a patient in a sitting position, when the air bubble may be out of the view, the instrument may contain a steel ball inside the chamber filled with liquid.
Patent EA-013298-B1 (EA)
Title: Method for inputting and searching information about an object in a remote database
Inventor: BREDIKHIN ALEXANDER YURIEVICH
IPC: G06Q30/02
Filed: 2007-06-04
Abstract: The inventive method consists in transmitting the object identifier-containing message from a mobile telecommunications terminal to a server by means of the network of a global mobile communication system via a cellular communication operator or by means of the Internet network. At least one word is used in the form of the object identifier-containing message transmitted from the mobile telecommunications terminal. The search of the object identifier in the server database consists in comparing the word with domain names by said server. While the user of the mobile telecommunications terminal determines the domain name, the server transmits the telephone number of a subscriber thereto. The mobile telecommunications terminal initiates communication for said telephone number by providing a voice connection with the telephone number of the subscriber. The method makes it possible to extend functional capabilities, to accelerate search, to reduce the amount of transmissible information and to reduce the loading of the telecommunications network and facilities thereof
Patent EA-016683-B1 (EA)
Title: Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and methods for its production
Inventor: JUNG GERD
IPC: A61K9/50
Filed: 2007-07-05
Abstract: A pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine, on the basis of active ingredient carriers provided with at least one active ingredient which are provided with an inner layer for controlling the active ingredient release and a covering layer, arranged thereon, that is resistant to gastric juices, and is characterized in that the inner layer is constructed from at least two diffusion layers whose permeability for the diffusing active ingredient decreases from the inside to the outside, and a method for its production are described.
Patent EA-017004-B1 (EA)
Title: Pyridizinone derivatives
Inventor: HUDKINS ROBERT L
IPC: C07D403/04
Filed: 2007-07-25
Abstract: The present invention provides compounds of formula (I*)their use as Hinhibitors, processes for their preparation, and pharmaceutical compositions thereof.
Patent EA-017231-B1 (EA)
Title: Separating device (variants) and method for using the same
Inventor: BOELE HENDRIK ARIE
IPC: B01D45/14
Filed: 2008-07-03
Abstract: The invention is directed to a plate type rotational separator for separating one or more components from a feed stream. The plate type rotational separator of the invention comprises plates that are able to spread out during cleaning. Different embodiments of the separator are also provided. The invention also relates to a method for separator operation.
Patent EA-018103-B1 (EA)
Title: Formwork for prismatic columns
Inventor: SANCHEZ RENASCO JESUS
IPC: E04G13/02
Filed: 2008-11-20
Abstract: Based on the conventional structure of formwork comprising an externally cylindrical tubular core (1), which, within, defines a prismatic housing (2), with a leaktight lining (3), said core being housed inside a surround (4) provided with hinging regions so that the formwork can be folded up when stored or transported, the features of the invention focus on the fact that the inner surround extends, with respect to the upper and also the lower end wall of the formwork, in the form of as many fins (6) as faces have been provided for the column or pillar, between which, when the formwork is assembled, an annular, laminar body (7), obtained from cardboard, plastic, wood or another material of suitable stiffness, externally encloses same, the internal dimensions whereof will be adapted to the dimensions of said column,; and the thickness or external dimensions whereof will be sufficient to constitute a formwork-stabilizing element, for which purpose provision has been made for said fins (6) to be able to fold and to attach to the surface of the annular body (7).
Patent EA-018053-B1 (EA)
Title: A method for the preparation of dabigatran
Inventor: JIRMAN JOSEF
IPC: C07D213/74
Filed: 2009-03-10
Abstract: A method for the manufacture of dabigatran of formula VIII, in which the product of a reaction of 4-ethylamino-3-nitrobenzoic acid chloride with ethyl-3-(pyridin-2-ylamino)propanoate, is converted to the hydrochloride using a hydrogen chloride solution producing the compound of formula III-HCl, in which the nitro group is reduced by means of a reaction with sodium dithionite, and the resulting compound of formula IV is subjected to a reaction with [(4-cyanophenyl)amino] acetic acid and oxalic acid, the product of this reaction VI-oxal is then subjected to hydrolysis and a reaction with ammonium carbonate to produce the intermediate of formula VII-HCl, which is then converted to dabigatran by means of a reaction with hexyl chloroformate.
Patent EA-020579-B1 (EA)
Title: Methods for treating reperfusion tissue injuries
Inventor: GUDKOV ANDREI V
IPC: A61K45/00
Filed: 2009-07-31
Abstract: The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin.
Patent EA-019852-B1 (EA)
Title: Pneumatic object provided with gas-tight layer comprising two thermoplastic elastomers
Inventor: LESAGE PIERRE
IPC: B32B25/04
Filed: 2009-11-30
Abstract: The present invention relates to a pneumatic object provided with an inflation gas-tight elastomer layer and comprises at least 50 pce of a block copolymer, comprising polystyrene and polyisobutylene, particularly of a SIBS, as the first thermoplastic styrene elastomer; at least 50 pce of an unsaturated thermoplastic styrene, particularly of a SIS, as the second thermoplastic styrene elastomer; and optionally an extension oil, particularly polybutene, preferably at a level of 5 to 100 pce. Said elastomer gas-tight seal layer has excellent sealing properties and a hysteresis that is comparatively lower than butyl rubber layers. The pneumatic object of the invention is in particular an inner tube or a tire for a vehicle.
Patent EA-022756-B1 (EA)
Title: Crystalline forms of eltrombopag and use thereof
Inventor: LEKSIC EDISLAV
IPC: C07D231/46
Filed: 2010-04-01
Abstract: The present invention relates to crystalline eltrombopag Forms I, III, V, XVI, the use of said crystalline forms for preparing eltrombopag ethanolamine salt, a process for preparing eltrombopag ethanolamine salt, a pharmaceutical composition for treating conditions leading to thrombocytopenia, the use of said crystalline forms as a pharmaceutical composition for treating conditions leading to thrombocytopenia, the use of said polymorph forms for the manufacture of a medicament for treating conditions leading to thrombocytopenia.
Patent EA-021933-B1 (EA)
Title: Ski transportation device by a user
Inventor: ESTRUGO MARI SABINA FRANCISCA
IPC: A63C11/02
Filed: 2011-02-25
Abstract: The device for ski transportation by a user comprises a supporting element for a ski that is placed beside the outer side of a ski boot, the supporting element having a movable part formed by a rotatable body and a fixed part on which the movable part is coupled rotatingly, while the rotatable body includes a receptacle for receiving the rear end section of the ski. It is characterized in that the receptacle of the rotatable body is delimited by an elastic frontal retaining and support rim (7) for the ski and adjustable runners (8) that can be adapted to the width of the ski (6).
Patent EA-026714-B1 (EA)
Title: Catalyst precursor and catalyst for the high-temperature (co)polymerization of alpha-olefins
Inventor: MASI FRANCESCO
IPC: C08F10/02
Filed: 2011-12-20
Abstract: A precursor for the formation of catalysts for the (co)polymerization of α-olefins, comprising titanium, magnesium, at least one metal selected from hafnium and zirconium, aluminum and chlorine, obtained with a process comprising treatment with a siloxane compound. Said solid precursor, used in combination with a suitable co-catalyst in high-temperature (co)polymerization processes of α-olefins, shows an improved productivity, a high incorporation of co-monomers in the copolymerization of ethylene and an increased thermal stability with respect to the systems so far in use.
Patent EA-029025-B1 (EA)
Title: Analogs of glucagon exhibiting gip receptor activity
Inventor: DIMARCHI RICHARD D
IPC: C07K14/435
Filed: 2013-06-18
Abstract: Provided herein are glucagon analogs which exhibit potent activity at the GIP receptor, and, as such are contemplated for use in treating diabetes and obesity. In exemplary embodiments, the glucagon analog of the present disclosures exhibit an ECat the GIP receptor which is within the nanomolar or picomolar range.
Patent EA-032703-B1 (EA)
Title: Method of treating wood objects, wood objects treated by the method and a mixture for use in the method
Inventor: SOKKA KASPERI
IPC: B27D1/04
Filed: 2013-12-23
Abstract: Provided are a method of protecting a wood object against the effects caused by, for example, fire or micro-organisms or insects, a wood object which is treated with this method, the treatment mixture and the use of the mixture. According to the present method, the wood object is treated with an active substance, which acts to protect against the unwanted effects of fire and/or micro-organisms or insects. According to the present invention, the active substance is mixed into an agent that increases the hydrophobicity of wood, and the mixture thus generated is applied onto the surface of the wood object at a temperature at which the agent that increases the hydrophobicity is in fluid form, and a coating film is generated onto the treated wood object, after which, finally, hot-pressing is carried out. In the way described, it is possible to migrate the active substance deep into the wood and make it remain there, in which case the washing out of the substance by rainwater is prevented or at least significantly delayed.
Patent EA-028443-B1 (EA)
Title: Pharmaceutical composition containing hyaluronic acid for use in the treatment of black disk disease
Inventor: GIORDAN NICOLA
IPC: A61L27/52
Filed: 2014-04-23
Abstract: The present invention describes and claims pharmaceutical compositions in gel form for use in the treatment of intervertebral disc degeneration, in particular the forms of dehydration and emptying of the nucleus pulposus known as "black disc disease". These compositions comprise a hyaluronic acid derivative which forms hydrogels with precise rheological characteristics that make it ideal for filling the nucleus pulposus.
Patent EA-030084-B1 (EA)
Title: Pneumatic atomizer (variants)
Inventor: MAL'TSEV LEONID IVANOVICH
IPC: F23D11/00
Filed: 2014-02-17
Abstract: Proposed is a variant of a pneumatic atomizer comprising a housing (1) with an internal annular gas chamber (3) and a pipe (2) for supplying a compressed gas thereto, a liquid supply pipe (4) disposed along the axis of the housing and transitioning into a diffuser (5), and an annular slotted gas nozzle (7) formed by an annular attachment (6) and the housing (1) of the atomizer at the outlet from the internal annular chamber (3). The annular slotted gas nozzle is mounted at the face of the diffuser (5) and has a conical shape with a taper angle of from 60 to 150 degrees, the internal annular gas chamber (3) of the atomizer is additionally provided with two nozzles (8) mounted opposite one another, wherein the axes of the nozzles intersect or cross such that the angle between the axis of each nozzle (8) and the axis of symmetry of the pneumatic atomizer is from 30 to 90 degrees, and the total area of the exit cross-section of the nozzles (8) is 0.3-1 of the area of the exit cross-section of the annular slotted gas nozzle (7). In a second variant of the pneumatic atomizer, the annular slotted gas nozzle (7) is mounted at the face of the diffuser (5) and has a conical shape with a taper angle of from 60 to 150 degrees, and the exit cross-section has a variable area around the perimeter of the ring. The design of the atomizers provides dispersivity in the atomization of liquids and suspensions without rapid wear on the equipment, and provides the possibility of adjusting the sizes and shape of a gas droplet jet.
Patent EA-031862-B1 (EA)
Inventor: PACH JOHN DAVID
IPC: C07C1/04
Filed: 2014-12-16
Abstract: Описан способ для загрузки емкости осецентробежного потока, содержащей слой катализатора в виде частиц, имеющий часть радиального потока и часть осевого потока, поддерживаемую и находящуюся в сообщении по текучей среде с частью радиального потока, путем (i) помещения первого материала катализатора в часть радиального потока и (ii) помещения материала второго катализатора в часть осевого потока, причем материал второго катализатора имеет более мелкие частицы, чем материал первого катализатора. Настоящее изобретение дополнительно предлагает емкость, загруженную материалами первого и второго катализатора.
Patent EA-036078-B1 (EA)
Title: Brake beam reinforcement system for 18-9996 model freight car truck
Inventor: ISENOV SHARIP MASHRABOVICH
IPC: B61H13/34
Filed: 2018-11-12
Abstract: The brake beam reinforcement system for 18-9996 type freight car truck relates to railway transport, in particular, to freight car truck rigging brake beams. The system consists of a string, bracing, beam, bracket, shoe, polymer journal sleeve of the brake beam. The beam and the string are connected together with a welded bracket. For beam flange thickness reinforcement, a 15-mm thick channel is used with a cover plate inside it and a 10 mm thick embedded piece across the channel, as a result the shoe attachment beam is 25 mm thick. To prevent any increase in the distance between the brake beam ends and the shoe centers, the string is replaced by a 36 mm diameter round steel bar. The essence of invention is characterized by the technical result: a bracket is added to the beam and string attachment design to prevent loading of stationary shoes and their further weakening in riveting points; beam flange thickness is increased up to 25 mm in shoe attachment points; 36 mm round steel bar is used instead of a string to prevent any increase in the distance between the brake beam ends and the shoe centers of one brake beam, said round steel bar being bent according to the brake beam shape.
Patent EA-038453-B1 (EA)
Title: 6-6 fused bicyclic heteroaryl compounds and their use as lats inhibitors
Inventor: BEHNKE DIRK
IPC: C12N5/079
Filed: 2018-04-26
Abstract: The invention relates to 6-6 fused bicyclic heteroaryl compounds or pharmaceutically acceptable salts thereof. The invention further relates to a pharmaceutical composition comprising the above compounds.
Patent ES-2190298-B1 (ES)
Inventor: AIZPURUA ZENDOIA INAKI XABIER
IPC: B21D5/04
Filed: 2000-01-31
Granted: 2004-10-16
Abstract: Columns (2) support horizontal beam (1) that extends over whole length of folding machine. Stem (17.2) of series of actuators (17) is connected to beam using first elbow joint (17.3). Body of actuators (17.1) is attached to pressure trolley (16) using second elbow joint (17.4). When actuators are retracted, jaws (4, 5) are in contact with each other. When actuators are opening out, and because stem is attached to horizontal beam, center of articulation axis (17.3) has to stay at same height, and body of actuators can only travel in ascending direction, so as to tilt pressure trolley in same direction until trolley reaches its upper position, where jaws are separated from each other.
Patent ES-2183697-B1 (ES)
Title: Llenadora automatica de envases.
Inventor: MORA CALLEJA SANTIAGO
IPC: B67C3/02
Filed: 2000-11-21
Granted: 2004-06-16
Abstract: Llenadora automática de envases. Un espadín (1) tubular, gobernador por un encoder (7) dispone de un accionamiento (4), respecto del eje de la boca del recipiente (2), en recorrido variable y con una barra axial (3) telescópica, desplazable por su interior, con accionamiento (5) y con una pieza discoidal oblicua (3.l), antagonista de la boca del espadín (1.1), de cierre o de dispensa del producto, además de un sensor de contacto (6) que actúa sobre los medios de accionamiento (4) y (5) y que arranca la cinta transportadora de avance de otro recipiente (2).