baber/WOPTO huggingface dataset:
Patent DE-68901667-T2 (DE)
Inventor: LAYLAND DAVID JOHN
IPC: F25J3/04
Filed: 1989-03-10
Granted: 1992-12-10
Abstract: Air from which carbon dioxide and water have been removed is subjected to fractional distillation in a first column 4 to form oxygen-nitrogen vapor and argon-enriched oxygen; argon is separated from the latter in a second column 10 operating at substantially lower pressure than the first; a portion of the nitrogen vapor is liquefied in a cycle including heat exchange with incoming air and compression to a pressure above that of the first column 4, and a portion of the liquid nitrogen is taken as product and a second portion is returned to the first column 4 as reflux. Liquid oxygen and nitrogen vapor from the first column are mixed in a liquid-vapor contact column 14, impure liquid nitrogen is withdrawn therefrom and used as reflux in the first column 4. A remixed oxygen-nitrogen stream is withdrawn from the column 14 and expanded to create refrigeration for the system.
Patent DE-68917901-T2 (DE)
Inventor: BLAIN JEFFREY WILLIAM
IPC: B66B1/04
Filed: 1989-12-21
Granted: 1995-02-16
Abstract: A hydraulic elevator system 10 having an elevator car 12 in which car velocity V and car position L are determined by detecting the quantity Q of hydraulic fluid transferred between a hydraulic cylinder and a hydraulic fluid reservoir. The car velocity V is directly proportional to Q and the car position L is directly proportional to the integral of Q. The car velocity V, or quantity Q, is compared with a desired velocity pattern, or desired flow rate pattern, PG, and the difference is a control signal C which is used to control the quantity Q. The car position L may also be used to determine the distance-to-go to a target floor, which may be used to initiate slowdown and/or to calculate all, or selected portions of, the desired pattern PG.
Patent DE-68918420-T2 (DE)
Inventor: GARREAU ROBERT
IPC: C25B3/23
Filed: 1989-12-05
Granted: 1995-05-04
Abstract: Substituted thiophenes of the general formula:  <IMAGE>  in which: R represents a hydrogen atom, a halogen atom or an aliphatic group containing from 1 to 4 carbon atoms, X represents a hydrogen atom or a fluorine atom, Y represents an at least partially fluorinated aliphatic or aromatic group, m represents an integer equal to or greater than 2, and n represents an integer such that 0</=n</=7. The invention also relates to the electrically conducting polymers containing recurring units derived from monomers chosen from the substituted thiophenes.
Patent DE-68922848-T2 (DE)
Inventor: FERREIRA NICHOLAS C
IPC: G01N29/34
Filed: 1989-02-22
Granted: 1995-09-14
Abstract: An ultrasonic sound echography technique is disclosed in which echo-masked zones of the workpiece are reduced by utilizing particular orientations of the beam of ultrasonic sound relative to formations in the workpiece. Echo-masked zones result from formations in the workpiece which reflect the ultrasonic sound waves back to the probe and therefore mask the much smaller echoes from anomalies, if any, in the workpiece. Instead of the conventional orientation of the beam, in which the scanning plane in which the beam lies is oriented perpendicularly to formations, the scanning planes are selected so as to be non-perpendicular with respect to such formations and to minimize the amount of masking echoes from the formations.
Patent DE-68923430-T2 (DE)
Inventor: FREYNE EDDY JEAN EDGARD
IPC: A61P43/00
Filed: 1989-11-28
Granted: 1996-02-15
Abstract: Novel (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives of formula <CHEM> the pharmaceutical acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein -X<1>=X<2>- is -CH=CH-, -CH=N-, or -N=CH-; R is hydrogen or C1-6alkyl; Y is hydrogen, C1-10alkyl, C3-7cycloalkyl, Ar<1>, Ar<2>-C1-6alkyl, C2-6alkenyl or C2-6alkynyl;  Z is a radical of formula <CHEM>   <CHEM> which compounds are useful for treating disorders which are characterized by an excessive proliferation and/or abnormal differentiation of epithelial tissues: pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent DE-69001848-T2 (DE)
Inventor: SASAKI YOSHIO
IPC: A61K8/00
Filed: 1990-03-30
Granted: 1993-09-16
Abstract: A skin-protective composition which comprises an acrylic copolymer which comprises     (A) 40 to 85 % by weight of an alkyl acrylate,   (B) 5 to 50 % by weight of an alkyl methacrylate, and (C) 10 to 30 % by weight of a mono-ethylenically unsaturated monomer having a carboxyl group, and a medium, which can effectively block irritative materials and be easily removed from a skin.
Patent DE-69003880-T2 (DE)
Inventor: ROBACHE PATRICK
IPC: B29C51/30
Filed: 1990-06-13
Granted: 1994-04-07
Abstract: This device is intended for the manufacture of packaging trays (1) two opposite parallel walls of which are inclined in relation to a plane perpendicular to the plane of closing of the walls. The two moulding or shaping pieces (12, 13) provided in this device are supported by mobile supports (14, 15) which are capable of ensuring their displacement along an axis (Z-Z') parallel to the inclined walls of these pieces, which correspond to the inclined walls of the packaging tray (1) to be made. This axis of displacement is thus inclined in the same manner in relation to a plane perpendicular to the plane of closing of this mould, which makes it possible to use simple moulding pieces constituted by an external female piece (12) and an internal stamp (13). The present invention also relates to a packaging plant incorporating such a manufacturing device (8), the latter being followed by a station (17) capable of ensuring the welding of a closure film (18) on the rim (3) of each of the trays (1). 
<??>The packagings made by means of this device and this plant can be used for packaging various products, in particular food products. 
<IMAGE>
Patent DE-69006872-T2 (DE)
Inventor: JAMES CLAUDE
IPC: A61K31/44
Filed: 1990-03-16
Granted: 1994-06-30
Abstract: New derivatives of formula (I) in which R1=H, halogen, alkyl, alkyloxy, CF3, NH2, alkylamino, dialkylamino, OH, CH, phenyl or phenoxy, Ar=phenyl, naphthyl, pyridyl, quinolyl, isoquinolyl, thienyl, thieno[2,3-b]thienyl or thieno[3,2-b]thienyl (these groups optionally substituted with halogen, alkyl, alkyloxy, CF3, NH2, alkylamino, dialkylamino, OH or CN), p=0, 1 or 2, and A-either Z=valency bond and R2=H B-or Z=valency bond and R2=pyridyl, quinuclidinyl, 3-pyrrolidinyl, 3- or 4-piperidyl (these groups optionally being substituted with alkyl, hydroxyalkyl, phenyl or phenylalkyl) C-or Z=alkylene radical (1 to 4C) and R2=2-, 3- or 4-pyridyl, 3-quinuclidinyl, 2- or 3-pyrrolidinyl, 2-, 3- or 4-piperidyl (optionally substituted with alkyl, hydroxyalkyl, phenyl or phenylalkyl) or R2=CON(R3)(R4) where a) either R3 and R4 form a piperazine optionally substituted with alkyl, hydroxyalkyl, pyridyl, phenyl or phenylalkyl, b) or R3=H, alkyl, phenyl or phenylalkyl, or (CH2)nN(R5) (R6) where 1<n<4 and R5 and R6=H, alkyl, phenyl, phenylalkyl, or R5 and R6 form a morpholine, thiomorpholine, pyrrolidine, piperidine or piperazine ring, (optionally substituted with alkyl, hydroxyalkyl, pyridyl, phenyl, phenylalkyl or phenylcarbonyl), and R4=(CH2)nN(R5)(R6) defined as above, D- or Z=alkylene (1 to 4C) and R2=N(R3) (R4) or N(R5)R6) where R3, R4, R5 and R6 are defined as above in C b), on the understanding that the alkyls contain 1 to 4C in a straight or branched chain and that the invention relates to the racemates, the enantiomers and mixtures thereof, the diastereoisomers, pure or mixed, and the E and Z isomers, as well as to the salts of these products.   <IMAGE> (I)
Patent DE-69007873-T2 (DE)
Inventor: SUDRON SERGE
IPC: G05B19/29
Filed: 1990-06-21
Granted: 1994-11-17
Abstract: Device for control of a winding element capable of moving between two extreme positions and driven by a motor (9) equipped with a position coder (10) and comprising means of control of the motor constituted essentially by a linear coder (6) with a cursor (11) and by a logic processing unit (2) recording the position of the cursor. The device additionally comprises two calibration contacts (13, 14) and two adjustment contacts (7, 8) making it possible to memorise two extreme positions of the winding element. The calibration contacts (13, 14) are arranged in such a way that they are actuated by the cursor (11) when the latter is at one or other of the extremities of its travel. This device eliminates the risks of error and of non-execution of a command. <IMAGE>
Patent DE-69011789-T2 (DE)
Inventor: HANSEN HANS J
IPC: A61K51/12
Filed: 1990-09-18
Granted: 1994-12-15
Abstract: A rapid and quantitative method for producing a sterile, injectable solution of Tc-99m-labeled monovalent antibody fragment comprises the step of mixing a sterile solution containing a monovalent antibody fragment having at least one free sulfhydryl group, stannous chloride and excess tartrate, at mildly acidic pH, or a sucrose-stabilized lyophilizate of such solution, with a sterile solution of Tc-99m-pertechnetate, whereby substantially quantitative labeling of the antibody fragment with Tc-99m is effected in about 5 minutes at ambient temperature, the resultant sterile solution of Tc-99m-labeled monovalent antibody fragment being suitable for immediate injection into a patient for radioimmunodetection.
Patent DE-69012248-T2 (DE)
Inventor: RICHARDSON MICHAEL M
IPC: B41J3/36
Filed: 1990-07-16
Granted: 1995-05-11
Abstract: A thermal printing device (10) and tape supply cartridge (11) therefor includes a printing mechanism having a printhead (24) incorporated within the machine and a separate printing platen embodied within the cartridge (11). An alignment mechanism (25) is also provided for insuring printing alignment between the cartridge embodied platen and the printhead (24). The cartridge (11) also includes a mechanism (35) for laminating a film of protective material over the printed tape and a fully incorporated, manually operated tape cut-off mechanism (36). <IMAGE>
Patent DE-69024020-T2 (DE)
Inventor: HOFMANN ALAN
IPC: A61P1/16
Filed: 1990-04-24
Granted: 1996-04-25
Abstract: A method and apparatus are disclosed for treating a patient having cholesterol calculi which involves infusing into the biliary tract of said patient a C5-C6 ester, ether or ketone having a boiling point in the range of 80 DEG -140 DEG  C or a mixture thereof in an amount and at a flow rate effective to at least partially dissolve said calculi rapidly. The invention also encompasses dissolving cholesterol calculi by exposing such calculi to contact with effective quantities of those solvent compounds. The apparatus includes a high flow rate catheter pumping system for infusing a gallstone dissolution solvent into the gallbladder of a patient and aspirating the gallstone dissolution solvent from the gallbladder, and a unit measure container of the solvent. The preferred esters, ethers and ketones are n-propyl acetate, isopropyl acetate, ethyl propionate, ethyl isobutyrate, cyclopentanone, 3-pentanone and methyl t-amyl ether. Contact flow rates are sufficiently high to insure fluid turbulence in the biliary tract region surrounding the calculi.
Patent DE-69027865-T2 (DE)
Inventor: MILJANICH GEORGE
IPC: C07K14/705
Filed: 1990-11-21
Granted: 1997-01-02
Abstract: A method of reducing neuronal damage related to an ischemic condition in a human patient, such as stroke-induced damage, by administration of a binding/inhibitory omega-conotoxin peptide.
Patent DE-69030131-T2 (DE)
Inventor: BARRY THOMAS GERARD
IPC: C12Q1/689
Filed: 1990-04-18
Granted: 1997-07-17
Abstract: A method for generating DNA probes specific for an organism and capable of distinguishing in a non-empirical manner between species. The method comprises amplifying, using a pair of oligonucleotide primers, a variable region of the genome of a number of phylogenetically related organisms to, or of a number of organisms suspected of being present in a given sample containing, said organism to be identified and having said variable region in its genome, at least one of said primers corresponding to a DNA sequence known or suspected of being conserved in said organisms, determining the sequence of the amplified region, selecting said sequence or a portion thereof to generate said probe specific for said organism to be identified by comparison with said other amplified regions and defining the hybridization conditions required to obtain a specific signal based on the precise nucleotide sequence of the selected probe. Specific probes are disclosed for a variety of species including Aeromonas hydrophila, Aeromonas salmonicida, Clostridium difficile, Mycobacterium bovis, Mycobacterium tuberculosis and Salmonella typhimurium.
Patent DE-69106701-T2 (DE)
Inventor: LACOSTE FRANCOIS
IPC: F16C11/10
Filed: 1991-04-05
Granted: 1995-07-13
Abstract: A positioning device for positioning an instrument in three dimensions, the device comprising at least one arm which is essentially rigid having a first end and a second end, the second end being hinged relative to a support stand via at least one hinge axis, and said instrument being mounted on a support which is connected to the second end of the arm via at least one hinge axis, wherein said instrument comprises an exploration probe and said support for the instrument comprises a device for motion in translation enabling the instrument comprising the exploration probe to be moved in translation relative to the second end of the arm, making it possible to perform exploration for each of the translation positions. The invention enables the instrument at the end of the positioning device to be moved in translation, thereby providing a maximum amount of freedom for positioning the instrument in three dimensions and facilitating locating operations, particularly in the context of transrectal echographic location, this being particularly useful for therapeutic treatment of the prostate.
Patent DE-69111386-T2 (DE)
Inventor: BIDNEY DENNIS
IPC: A01H1/00
Filed: 1991-11-11
Granted: 1996-01-04
Abstract: Bacteria of the species Agrobacterium are applied to particles which are used in a typical particle gun in a manner which retains their viability after the dry-down process involved in microparticle bombardment. When plant materials are bombarded with particles coated with the bacteria, high rates of stable transformation are achieved.
Patent DE-69117641-T2 (DE)
Inventor: PAGANI GIORGIO
IPC: C07C273/04
Filed: 1991-09-25
Granted: 1996-10-02
Abstract: A process is described for the industrial synthesis of urea, making the ammonia (NH3) and the carbon dioxide (CO2) react, in at least one reaction space, at high pressures and temperatures and recycling at least in part the unreacted products obtained in a recycle section, characterized by: a) a synthesis reaction between reactants of high purity; and b) a synthesis reaction between less pure reactants, substantially recycled by the so-called recycle section. The corresponding new plant includes a reactor (R1) of high yield ("once through"), a reactor (R2) of lower yield and a section of recovery and recycle. The application of the process to preexisting plants requires the simple addition of a reactor of high yield and of pumping devices. <IMAGE>
Patent DE-69131295-T2 (DE)
Inventor: GLUCHOWSKI CHARLES
IPC: A61K31/535
Filed: 1991-09-10
Granted: 2000-01-27
Abstract: Compounds having  alpha  adrenergic activity and useful for the treatment of glaucoma, renal and gastrointestinal disorders and vasoconstictors have the formula  <IMAGE>  where R1 is independently H, or lower alkyl or 1 to 6 carbons; R2 is independently H, or lower alkyl of 1 to 6 carbons or the two R2 symbols jointly represent a carbonyl oxygen; R3 is H, lower alkyl of one to 6 carbons, O, OH and OR7 where R7 is lower alkyl of 1 to 6 carbons, or R3 is COH or COR8 where R8 is lower alkyl of 1 to 6 carbons; R4 and R5 independently is H, Br, Cl, or lower alkyl of 1 to 6 carbons, lower alkenyl or lower alkynyl with the proviso that when the R2 groups symbolize a carbonyl oxygen then R4 and R5 both cannot be hydrogen; R6 is hydrogen, Br, Cl, or lower alkyl of 1 to 6 carbons, lower alkenyl or lower alkynyl, and the R5 and the (2-imidazoline-2-yl)amino substituents are connected mutually exclusively to the 6 and 7 positions of the 1,4-benzoxazine nucleus.
Patent DE-69132662-T2 (DE)
Inventor: ZELIN P
IPC: G01N27/28
Filed: 1991-07-19
Granted: 2002-05-23
Abstract: A reusable test unit is disclosed for testing the functionality of a portable blood analyzer, and particularly the interface between the high-impedance electrochemical sensors and the instrument. Signals are generated to simulate amperometric, conductimetric, and potentiometric sensors. Circuitry permits detection and discrimination between failures from damaged CMOS amplifiers and failures from leakage currents in contaminated connectors. The test unit may be configured to be insertable into the instrument to fit mechanically in the same fashion as a disposable sensor device. A scheme for three-dimensional routing of guard lines on a circuit board is disclosed for guarding against coupling between closely space traces and connector pads.
Patent DE-69203845-T2 (DE)
Inventor: GRAS TREVINO JOSE MARIA
IPC: H02M3/335
Filed: 1992-12-05
Granted: 1996-04-04
Abstract: Applicable to non-resonant switched mode power supplies with voltage regulation by means of pulse width modulation. Its objective is to achieve a reduction in the amplification in the value of input capacitance (Miller effect) at the instants of switching of the MOSFET rectifier transistors, and to prevent the appearance of a shortcircuit in the main power supply unit at such instants. The first of these objectives is achieved by having the switching of the MOSFET rectifier transistors take place at a value of drain-source voltage equivalent to the cathode to anode voltage drop of a conducting diode (approximately zero volts). The second objective is achieved assuring that change of state from cutoff to conduction, or vice versa, of the MOSFET rectifier transistors never occurs simultaneously with the change of state of the other switches in the converter. <IMAGE>
Patent DE-69207748-T2 (DE)
Inventor: KOLJONEN KARI
IPC: A22C25/16
Filed: 1992-01-15
Granted: 1996-08-22
Abstract: Fish bones (9) are removed from fish (8) by means of a device which includes a housing (3) which accommodates a rotatable roller (1). The roller (1) is provided with bone-engagement means (2) which pass across an opening (4) in the housing (3) as the roller rotates. Mounted at that end of the opening (4) to which the engagement means (2) move during rotation of the roller (1) is a counter-pressure device (6) and a gap is defined between the counter-pressure device (6), at the free edge (7) thereof adjacent the opening (4), and the engagement means (2). Fish bones (9) partially enter the gap and are clamped or pinched between the free edge (7) and the bone-engagement means (2), so as to be drawn from the flesh of the fish (8) as the roller (1) rotates, while the fish flesh (8) from which bone is withdrawn is held in place by that side of the counter-pressure device (6) which faces towards the flesh (8).
Patent DE-69228997-T2 (DE)
Inventor: VADAS MATHEW
IPC: C07K14/54
Filed: 1992-10-07
Granted: 1999-08-26
Abstract: PCT No. PCT/AU92/00535 Sec. 371 Date Jun. 20, 1994 Sec. 102(e) Date Jun. 20, 1994 PCT Filed Oct. 7, 1992 PCT Pub. No. WO93/07171 PCT Pub. Date Apr. 15, 1993This invention relates to human IL-3 variants. The human IL-3 variants are used in pharmaceutical compositions, in methods for modulating proliferation, differentiation or functional activation of cells expressing the IL-3 receptor, and in methods of treatment.
Patent DE-69231415-T2 (DE)
Inventor: OSHLACK BENJAMIN
IPC: A61K9/22
Filed: 1992-04-15
Granted: 2001-03-29
Abstract: A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and relative humidity elevated to a suitable level above ambient conditions until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity. <IMAGE>
Patent DE-69232418-T2 (DE)
Inventor: DEAN T
IPC: C07F13/00
Filed: 1992-11-19
Granted: 2002-10-31
Abstract: This invention relates to therapeutic reagents and peptides, including radiotherapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labeled radiodiagnostic agents. Specifically, the invention relates to cyclic peptide derivatives and analogs of somatostatin, and embodiments of such peptides radiolabeled with a radioisotope, as well as methods and kits for making, radiolabeling and using such peptides for radiodiagnostic and radiotherapeutic purposes. The invention specifically relates to cyclic peptide derivatives and analogues of somatostatin radiolabeled with technetium-99m and uses thereof as scintigraphic imaging agents. The invention also specifically relates to cyclic peptide derivatives and analogues of somatostatin radiolabeled with cytotoxic radioisotopes such as rhenium-186 (186Re) and rhenium-188 (188Re) for use as radiotherapeutic agents. Methods and kits for making, radiolabeling and using such peptides diagnostically and therapeutically in a mammalian body are also provided.
Patent DE-69308332-T2 (DE)
Inventor: ROBLES GUILLERMO
IPC: G11B23/26
Filed: 1993-11-24
Granted: 1997-08-14
Abstract: A new generation magnetic tape cartridge of the type having a leader block is provided along with a new generation leader block pin so as to prevent interlocking with respect to prior art leader blocks and leader block pins. The magnetic tape cartridge is a generally rectangular container which has four corners. One of the corners of the container is beveled and is provided with a well to receive the new generation leader block in a nested position. The new generation leader block has a notch which has top, bottom and middle portions. A cross section of the middle portion of the notch is smaller than the cross section of the bottom portion of the notch, and the cross section of the top portion of the notch is smaller than the cross section of the middle portion of the notch. The cross section of the bottom portion of the notch is defined by a circular arc of more than 180 DEG  for receiving and capturing a new generation leader block pin. The top portion of the notch in the block is fashioned to confine the new generation leader block pin to a predetermined amount of lateral movement. The configurations of the notch of the new generation leader block and the new generation leader block pin are fashioned to prevent interlock with prior art reader blocks and leader block pins.
Patent DE-69309958-T2 (DE)
Inventor: HARDY ROBERT
IPC: C07C57/30
Filed: 1993-11-30
Granted: 1997-07-24
Abstract: PCT No. PCT/EP93/03376 Sec. 371 Date Jun. 21, 1995 Sec. 102(e) Date Jun. 21, 1995 PCT Filed Nov. 30, 1993 PCT Pub. No. WO94/12460 PCT Pub. Date Jun. 9, 1994A process for the production of a product which is enriched in a desired enantiomer of a phenylpropionic acid selected from ibuprofen and flurbiprofen, or their pharmaceutically acceptable salts, which comprises a resolution stage, a recrystallization stage, an optional liberation stage, and an optional salt preparation stage. A substantially racemic mixture of the phenylpropionic acid is contacted with an enantiomer of  alpha -methylbenzylamine, in specific ratios, to produce the enantiomerically enriched product.