baber/WOPTO huggingface dataset:
Patent AU-2021100586-A4 (AU)
Title: A PD-1 Nanobody and Its Preparation Method and Application
Inventor: CHEN CHUANGFU
IPC: C12N15/85
Filed: 2021-01-29
Granted: 2021-04-15
Abstract: The invention belongs to the technical field of biomedicine, and particularly relates to a 
programmed death 1 (PD-1) nanobody and its preparation method and application. The 
use of nanobody can improve or synergistically enhance the binding ability with antigen.  
Nanobody does not have a complete antibody structure, lacking Fc end and Y-shaped 
structure. Therefore, it is difficult for antigen to be recognized after binding with 
nanobody, that is, it can easily escape the capture of immune system. The invention 
mainly includes the following technical means. Connecting the antigen with vector and 
transferring it into competent cells to extract the recombinant plasmid, which is then 
transfected into host bacteria for expression. Next, using antigen protein to immunize 
camel animals, collecting peripheral blood, and extracting total RNA of lymphocyte 
sample, which is then reverse transcribed into cDNA and amplified to obtain VHH 
library fragment. Then antibody immune library is constructed by inserting VHH library 
fragment into expression vector and transforming it into competent cells. Finally, the 
nanobody in antibody immune library is screened and the binding ability of the nanobody 
with PD-i antigen is verified.
-1/14
Synthesis and amplification of PD-1 immune antigen fragment 
After transferring the ligation solution into competent cells, 
extracting recombinant plasmids.  
Transfecting the recombinant plasmids into host bacteria to express 
the antigen 
Immunizing camel animals by the antigen protein 
Collection of peripheral blood of immunized camel animals and 
separation of lymphocytes.  
The total RNA of lymphocyte sample is extracted, and reverse 
transcribed to cDNA 
Amplification of VHH fragment and insertion of expression vector 
Construction of an antibody immune library 
Biotinylated screening of nanobody 
Verification of the binding ability of the nanobody to antigen 
Figure 1 
A flow chart of PD- nanobody construction.
Patent AU-2021102562-A4 (AU)
Title: Model Integration Method for Identification and Tracking of PM2.5 Pollution Source
Inventor: DAI XIAOYAN
IPC: G06F16/28
Filed: 2021-05-14
Granted: 2021-07-01
Abstract: The invention relates to a model integration method for identification and tracking of 
PM2.5 pollution source. The method includes the following steps: 1) Collection of historical 
data, including time series data of wind speed, wind direction and PM2.5 concentration values; 
2) Construction of bivariate polarization diagram based on the historical data; 3) According to 
the characteristics of bivariate polarization diagram, cluster analysis is used to realize the 
automatic classification and identification of PM2.5 pollution sources. After identifying PM2.5 
pollution sources, the influence factors of pollution diffusion are identified by calculating the 
contribution values of different pollution sources. Compared with existing technologies, the 
invention has the advantages of high recognition accuracy and automatic classification.
1/6 
FIGURES 
Time series data 
PM-5concentration Wind speed and direction 
Construction of bivariate polarization diagram 
Identification and grouping of sources of atmospheric 
particulate matter 
Calculation of contribution value of pollution source 
Discrimination of Influencing Factors of Pollution Diffusion 
Figure I
Patent AU-2021104668-A4 (AU)
Title: Three-dimensional mud-pressure blasting method for strengthening straight-hole comprehensive spiral deep-hole cutting in hard rock double-row and same-depth wedge-shaped blind area in railway double-track tunnel
Inventor: ZHANG XIN
IPC: F42D1/22
Filed: 2021-07-28
Granted: 2021-10-21
Abstract: Disclosed is a three-dimensional mud-pressure blasting method for strengthening 
straight-hole comprehensive spiral deep-hole cutting in hard rock double-row and 
same-depth wedge-shaped blind area in railway double-track tunnel, said method 
relates to technical field of tunnel construction, comprising steps as blasthole location, 
hole drilling, blasthole cleaning, charging and blasting, etc.; this invention realizes 
deep hole blasting, speeds up construction progress, increases economic benefits, and 
forms a benign working cycle.
DRAWINGS 
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F3 F3F1 25 
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M~ 0 0T s 
F4 F1 FW1F2 2 BT3 Z32 
F0 0 0 0 0 00 02 Z2 F70 M F6B F67 F65 F64 Z33 
z1 
FIG.1 
1 
45 0 
(F) 
(F) 
(F) 
(T) 
(T) 
(BT) 
(T) 
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FIG.2 
1
Patent AU-2021105651-A4 (AU)
Title: A Paring Tool for Cinnamon Tree
Inventor: YANG BAOJIAN
IPC: B27L1/00
Filed: 2021-08-17
Granted: 2021-10-14
Abstract: of Descriptions 
The invention discloses a paring tool for cinnamon tree, which comprises: A positioning 
mechanism, which is used to position the cinnamon tree and drive the cinnamon tree to rotate; a 
paring mechanism, which comprises a first driving device, a second driving device and a paring 
tool, the first driving device drives the paring tool to move along the direction of Y, and the second 
driving device drives the paring tool to move along the direction of X. The fixed mechanism 
clamps the trunk, and then the first driving device drives the paring tool to approach the trunk 
along the direction of Y, so that the paring tool just butts with the trunk, and then the fixed 
mechanism drives the trunk to rotate, meanwhile, the second driving device drives the paring tool 
to move along the direction of X, so that the paring tool can pare off the bark along the shaft of the 
trunk, so as to realize automatic paring, reduce labor intensity and improve efficiency.
1/2 
221 235 231 
232 222 224 211 
233 42 
22 3--- 212 
111 
112 121 
Y 
x 
Fig.1 
224
243
242 -
241 211 212 
Fig.2
Patent AU-2021107290-A4 (AU)
Title: Lift-Up Door Drive System
Inventor: TREWARN JEREMY
IPC: E05D13/00
Filed: 2021-08-25
Granted: 2021-12-09
Abstract: A motorization trolley which when used in the operation of a counterweight plus electric 
drive lift-up door system allows both the counterweight and drive motor to be connected to 
the door panel at a single point.
10 
Figure 2 
1k 
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0k 
Ck 
0k
Patent AU-2022100109-A4 (AU)
Title: Materials and methods for increasing the tocopherol content in seed oil
Inventor: ANDRE CARL
IPC: C12N15/82
Filed: 2022-08-17
Granted: 2023-02-02
Abstract: MATERIALS AND METHODS FOR INCREASING THE TOCOPHEROL CONTENT IN SEED OIL 
5 The present invention relates generally to the field of molecular biology and concerns increasing 
the tocopherol content of a plant relative to a control plant, comprising expressing in a plant at 
least one polynucleotide encoding a delta-12-desaturase, at least one polynucleotide encoding a 
delta-6-desaturase, at least one polynucleotide encoding a delta-6-elongase, and at least one 
polynucleotide encoding a delta-5-desaturase. The present invention also relates to methods for 
0 the manufacture of oil, fatty acid- or lipids-containing compositions, and to such oils and lipids as 
such.  
18945905_1 (GHMatters) P43640AU02
Patent WO-2010081203-A4 (WO)
Title: Appareil à des fins de serrage sur les dents inférieures ou supérieures, et activateur comportant un tel appareil
Inventor: NELISSEN FRANS JOSEF
IPC: A61F5/56
Filed: 2010-01-08
Abstract: L'invention concerne un appareil qui peut être placé par serrage sur une mâchoire inférieure ou supérieure, en particulier sur les molaires et/ou prémolaires de celle-ci, se composant sensiblement de : - au moins un corps façonné buccal coté gauche et un corps façonné buccal coté droit se trouvant du côté buccal ; - un ou plusieurs éléments de raccordement entre le corps façonné buccal côté gauche et le corps façonné buccal coté droit, le corps façonné buccal coté gauche et le corps façonné buccal côté droit s'étendant de manière respective au moins le long des molaires et/ou prémolaires et/ou canines coté gauche et côté droit ; et lesdits un ou plusieurs éléments de raccordement étant adaptés pour pousser les corps façonnés côté gauche et côté droit dans les zones de contre-dépouille des molaires et/ou prémolaires et/ou canines.
Patent WO-2009044008-A4 (WO)
Title: Dispositif de recuperation du mouvement de la mer pour le transformer en energie electricque
Inventor: MORCILLO ELEZ JOSE
IPC: F03B13/18
Filed: 2008-07-24
Abstract: L'invention est constituée d'une structure (2) dans laquelle est posé un piston flotteur (19), par le fait du mouvement de la mer il va glisser de bas en haut et transmettre sont mouvement à travers d'une bielle (3) sur les volants d'inertie (9), pour être transformé en mouvement rotatif sur les boites d'engrenages (7), lesquelles sont reliés aux générateurs (6) qui le transforment en courant.
Patent WO-2019030637-A4 (WO)
Title: Device for the separation and hbyridisation of renewable energies
Inventor: STECLEBOUT THIERRY
IPC: F24D3/08
Filed: 2018-08-05
Abstract: The invention relates to a device for the hydraulic separation and hybridisation of renewable energies for the purpose of heating buildings. The invention relates to a solar thermal system, the performance of which is amplified by a hydraulic device for separating the primary circuit in order to form the secondary circuit, to which the heating capacity of a renewable electricity production system is added. The hydraulic separator device consists of two separator vessels (8) and (9) connected to one another. A controlled stop valve (V17) is inserted on one of the two connectors. An electrical heat resistor (R12) is integrated into the first vessel (8), providing freeze protection for the heat transfer fluid which can be then be clear water. An electrical heat resistor (R13) is integrated into the second vessel (9), providing the additional energy necessary for the domestic hot water production and heating system.
Patent WO-2009113093-A4 (WO)
Title: Composition herbicide
Inventor: SHORFF VIKRAM RAJNIKANT
IPC: A01N25/26
Filed: 2009-01-21
Abstract: La présente invention a trait à une composition herbicide comprenant un premier ingrédient actif, du clodinafop-propargyl, et un second ingrédient actif, du metsulfuron méthyle, le metsulfuron méthyle étant présent sous forme de particules sur lesquelles est diposé un revêtement sensiblement homogène ou un matériau inerte hydrophobe. La présente invention a également trait à des processus permettant de préparer ladite composition herbicide.
Patent WO-2012091592-A4 (WO)
Title: Ballon gonflable pour des activités de football et de loisirs
Inventor: RUA MARIA HELENA NEVES PEREIRA RAMALHO
IPC: A63B41/08
Filed: 2011-12-16
Abstract: L'invention concerne un ballon gonflable (1) pour des activités de football et de loisirs. L'invention est basée sur un nouveau modèle géométrique. L'invention considère l'utilisation de surfaces courbes pliables non roulées - des surfaces cylindriques - pour créer des structures tridimensionnelles sphériques - des dômes et des géoïdes - pour remplacer les structures actuelles qui utilisent des figures géométriques planes telles que l'icosaèdre tronqué. Il s'agit d'une configuration correspondant à un ballon (1) ayant 12 faces ou panneaux (2), 24 arêtes (3) et 14 sommets, six sont du type (A) et huit sont du type '(B), ceci tirant parti de la courbure des solides pour reproduire une figure sphérique gauchie et de plus des moules ne sont pas nécessaires pour les réaliser. L'avantage est que l'invention peut être réalisée en se basant sur le développement des surfaces.
Patent CH-688501-A5 (CH)
Title: Joint between wooden furniture components e.g. high-level bunk bed
Inventor: KROPF MARTIN
IPC: A47C19/00
Filed: 1995-01-24
Abstract: The joint comprises a metal plate (19) held by screws (17,18) in slots (16) in both furniture components. The plate can be angled at the butting faces of the components (2,3,7) and the screws can have countersink or counterbore heads. The plate can have a connecting line between halves of different shapes at the butt-joint. The plate can be steel and roughly 4 mm thick, and it can have a roughened surface. Where a vertical post with inserted metal bush is fitted over a drawer, a metal plate with drilling can be inserted in a slot in the post, with the bush fitting in the drilling. The plate bears at right angles against the drawer, and a further metal plate with screws clamps two wooden components against the drawer, these butting against the post.
Patent CH-640252-A5 (CH)
Title: Curable mixture for the preparation of reinforced, elastomeric, epoxy resin-based plastics
Inventor: SCHMID ROLF DR
IPC: C08G59/26
Filed: 1979-01-16
Abstract: The mixture contains, as reinforcing agent, needle-shaped crystals of the product of the reaction of aluminium oxide or hydroxide and acetic acid, propionic acid or benzoic acid. These improve certain mechanical properties of the elastomeric polymers obtained by curing the epoxy resin/curing agent mixtures, without the elastomeric properties being lost.
Patent CH-578849-A5 (CH)
Title: Portable table with folding legs and struts - leg hinges have split bearings provided with clamping nuts
IPC: A47B3/08
Filed: 1975-01-20
Abstract: The table top has a stiffening board (2) fixed to its undersurface near the edge of its longer sides. A split bearing forms a shaft which forms a hinge pin for the pair of legs (3). When the legs are in the vertical position, the nut (15) is tightened on the bolt (15) to close the gap (13) of the split bearing and to eliminate any play in the hinge. The leg pair (3) is also supported by the pair of struts (5) which are fixed by the hinges (17) to the undersurface of the table and by the bolt (19) and nut (21) to the cross beam of the leg pair (3).
Patent CH-661679-A5 (CH)
Inventor: GABEL JEAN PAUL
IPC: B25B9/02
Filed: 1985-02-20
Abstract: The tweezers (1) have a rigid closing ring (9) sliding without friction between the back end (5) of the tweezers, where the two legs of the tweezers are joined together, and the front (4) of the tweezers, where the tips (3) of the tweezers are located. Beyond the length over which it slides without friction, the ring (9) can slide further forward, overcoming friction and closing the tips (3) of the tweezers. It can also slide backwards beyond the frictionless length, until it either encounters a stop or experiences friction.
Patent CH-669951-A5 (CH)
Title: Producing semiconductor strontium titanate particles
Inventor: GONZALEZ CARLOS-OLIVER
IPC: H01B3/12
Filed: 1986-04-03
Abstract: Sr, Ti and dopant metal sources are mixed, where at least one of corresp. organic alkoxides are involved in the mixt. The alkoxide is transformed into gel using the sol.-gel technique. The mixt. is dried and fired in H2, CO or inert gas atmos. Then, the reduced powders are pulverised into the semiconductor SrTiO3 particles having a desired particle size. The high dielectric ceramics are produced as: (a) the semiconductor SrTiO3 particles are mixed with (Nb)SrTiO3 particles which work to lower sintering temp. and to promote insulating grain boundary formation; (b) the mixt is press-moulded; (c) then the mouldings are fired at 1000-13000 deg.C in N2, H2/N2 or CO/CO2 atmos.
Patent CH-664474-A5 (CH)
Title: Spiked running shoe for competition use - has wedge insert above heel for good starting position and overall design to optimise running action
Inventor: PINA GIUSEPPE
IPC: A43C15/16
Filed: 1985-04-26
Abstract: The spiked running shoe for track events incorporates a wedge shaped insert (3) above the heel, so that the sole (2) of the foot slopes downwards from the rear.  This supports the foot in the most favourable position when it is resting on a starting block at the beginning of a race. The design is also most favourable for foot movements during running, enabling fast speeds to be achieved.  The spikes (5,6) are designed to reduce the amount of soil loosened due to the running action. Under the tip of the toe are grooves to improve the grip.  The single spike (5') under the tip of the toe has a rounded front face and the single spike (6') at the rear has a rounded rear face.  The other front spikes (5) have backwardly sloping rear faces.  The other two rear spikes (6) have forwardly sloping front faces. The material of the toe is very flexible. ADVANTAGE - Improved foot action for high running speeds.
Patent CH-682299-A5 (CH)
Inventor: KOHLRUSS GREGOR
IPC: D06M101/08
Filed: 1990-11-08
Abstract: The invention concerns a disposable duster consisting of a piece of a dry natural fibre fabric consisting of a light to white coloured soft open-pored paper as the absorbent cellulose material with less than 10 % filler which is impregnated with wax which is biodegradable and is hard enough to prevent the erosion of the natural fibre fabric. The wax should be a natural one of vegetable or animal origin, preferably a carnauba or beeswax, or a synthetic or chemically modified wax, preferably a paraffin, an oxidised polyethylene wax or a hydrated jojoba oil.
Patent CH-668886-A5 (CH)
Title: Prodn. of cheese and cream cheese - by skimming milk re:structuring cream under pressure, adding to milk and curdling with lactic acid bacteria
Inventor: VISZLAI BELA DR
IPC: A23C9/15
Filed: 1988-07-12
Abstract: In prodn. of cream cheese and cheese prods., (a) milk is skimmed, (b) the cream, with 12-25% fat content, is subjected to colloidal/chemical restructuring at 50-80 bar, pasteurised at 86-90 deg.C, and cooled, (c) the fat content of the basic milk is adjusted by addn. of the cream, (d) lactic acid bacteria are added, and the prod. is curdled, disintegrated, heated,  sepd., shaped and/or seasoned, and (e) the prod. is packed. ADVANTAGE - The quality of milk prods. obtd. from whey is improved, and less whey occurs as a by-prod.; the fat content of the whey is zero (compared with 0.2 vols.% in known processes), and the total protein content is 22-25% lower. The vat milk is not skimmed during curdling, and the fat distribution is homogeneous. The dry matter content is raised by about 50%, and about 15% less basic material is needed to produce 100 kg of semi-fat cream cheese. The prods. have a fuller taste and aroma, and cream cheese has better keeping qualities.
Patent CH-670241-A5 (CH)
Inventor: WEBER HEINZ
IPC: A47B53/02
Filed: 1986-07-11
Abstract: The storage rack (1) has, fastened in its chassis (9), sliding elements (15) which are situated between running rollers (5). The sliding element (15) is a plastic or metal body composed of a basic body (16) and two sliding bodies (19, 20). The sliding bodies (19, 20) engage over a conveying rail (6) and form, together with the lateral faces (26) of the conveying rail (6) the lateral guide of the chassis. In comparison with known embodiments, this lateral guide is simpler, maintenance-free and has a longer life. <IMAGE>
Patent CH-680725-A5 (CH)
Title: Plastics foil security closure for bottles - includes capsule with dye to indicate if tampering has taken place
Inventor: MODEL PETER L
IPC: B65D41/62
Filed: 1991-09-30
Abstract: The plastics foil (5) is shrink-fitted onto the container neck (1). The upper horizontal surface of the foil is transparent and the security capsule (8) is welded on the inside of this surface in the centre to extend over the entire opening area of the container. Between the plastics foil and security capsule is an air space (11) containing the substance which changes colour should the security capsule be broken. The neck opening of the container is preferably closed by a breathable cork (4) and the plastics foil can have one or more ventilation holes (9) inside the cover area of the capsule. USE - To guard against the contamination of wines, medicines, etc.
Patent CH-685427-A5 (CH)
Inventor: DUBS JAKOB ULRICH
IPC: A63F9/08
Filed: 1991-11-15
Abstract: The ring, which is suitable as a toy, but can also for example be worn around an arm or finger, consists of a first part-ring (1a) and a second part-ring (1b) which are connected to each other to be rotatable about a first axis (2a) of rotation, forming a common diameter, and a third part-ring (1c) which is connected to the second part-ring (1b) to be rotatable about a second axis (2b) of rotation enclosing a right-angle with the first axis (2a) of rotation. From a basic position, in which the part-rings (1a, 1b, 1c) lie in the same plane and part-rings rotatably connected to each other (1a, 1b; 1b, 1c) contact each other laterally between the intersections (3a, 3b; 3c, 3d) about the respective axis (2a; 2b) of rotation at which they cross each other, touch each other laterally at fitting surfaces (4) parallel to the plane of the ring, and together form a complete, convex cross-section of a shape which is identical over the entire circumference of the ring, the ring can be folded open to form a three-dimensional configuration, the angles of rotation being limited by stops (5a, 5b). <IMAGE>
Patent CH-681214-A5 (CH)
Title: Assembly of metallic parts
Inventor: MELLERET PAUL
IPC: B23K1/18
Filed: 1989-10-18
Abstract: Two metallic parts are assembled by (a) forming a conical surface (11) with protrusions (12) on one (10) of the parts; (b) forming a smooth complementary conical surface (21) on the other part (20); (c) applying a brazing film (16) onto one (11) of the surfaces; (d) heating the parts (10, 20) to the brazing film melting temp.; and (e) force fitting the two parts together.
Patent CH-679312-A5 (CH)
Inventor: NAZMY MOHAMED DR
IPC: C22C30/00
Filed: 1989-11-03
Abstract: Oxidation- and corrosion-resistant high-temperature alloy based on an intermetallic compound of the chromium silicide type, having the following composition:     Si = 23 - 27 atom %,   Mo = 5 - 20 atom %,   W = 1 - 3 atom %,   B = 0 - 1 atom %,   Cr remainder   The alloy has at least 90% by volume, based on the totality of intermetallic phases, of Cr3Si and Mo3Si. <IMAGE>
Patent CH-609853-A5 (CH)
Title: Device for heating up the contents of a drinking vessel
Inventor: HAUPT ADOLF
IPC: B60N3/10
Filed: 1975-05-07
Abstract: A device for heating up the contents of a drinking vessel has a heating pot (4) which can be connected to an electrical power source. A handle (6) which, when set down, serves at the same time as support against tipping over is connected to the heating pot. A connection sleeve (10), fastened in an articulated manner and directed away from the handle, is intended to be able to connect the appliance to a plug socket or a contact socket inside a car. <IMAGE>
Patent CH-560937-A5 (CH)
Title: Mail postal code system - uses machine readable symbols each formed by sixteen segments
IPC: G06V30/224
Filed: 1971-04-02
Abstract: The sixteen segments by which each symbol is defined are printed on the front of an envelope in a chosen position, and the symbol is denoted by marking the lines around selected segments, so that a postal code can be defined by a series of such symbols. The symbols are scanned by a reading head, having 16 photocells, each corresponding in position to one of the 16 segments, so that the presence or absence of the marked lines of the segments allows the symbol to be obtained. The segments may be formed by the sides of a square and by its diagonals and dissection lines, or by the circumference and diagonals of a circle.
Patent CH-586987-A5 (CH)
Title: Temp. control in furnace for magnesium treated cast iron - switching electrical heating rods cyclically in equally distributed groups depending on actual and desired values
IPC: H05B3/00
Filed: 1975-04-18
Abstract: A thermostat control loop connects up only one heating element or one group of element at a time for a short period depending on a comparison of actual and desired preset temp. A thermocouple produces a signal which is compared with that set by a desired value setter. If too high, a control unit cuts out the main contactor for the heating rod elements. If too low, a desired value generator is activated and its output is compared in a comparator with that of another thermocouple. This combines a uniform temp.distribution with a controlled heating-up and min. fluctuations of a set temp. The energy requirement is a min. and the mains supply is loaded symmetrically. The life of the heating rods is increased and no expensive variable voltage transformers are required.