baber/WOPTO huggingface dataset:
Patent DE-69534383-T2 (DE)
Inventor: ALMSTEDT ANNELIE
IPC: A61K38/37
Filed: 1995-11-14
Granted: 2006-05-24
Abstract: PCT No. PCT/SE95/01351 Sec. 371 Date May 30, 1997 Sec. 102(e) Date May 30, 1997 PCT Filed Nov. 14, 1995 PCT Pub. No. WO96/15150 PCT Pub. Date May 23, 1996A process for reducing degradation of recombinant coagulation factor VIII caused by metal-dependent proteases requiring Zn2+ for activity or containing Zn2+ as an integral part of their structure comprises adding an inhibitor of Zn2+ dependent proteases to a recombinant factor VIII solution. The recombinant factor VIII solution is obtained after harvesting a conditioned medium from a cell culture used for producing the recombinant coagulation factor VIII. The inhibitor is selected from complexing agents with a stronger affinity for the Zn2+ ion of the protease than for the ion or ions stabilizing the factor VIII molecule, and compounds structurally related to the natural substrate of the protease and containing an electronegative moiety.
Patent DE-69602692-T2 (DE)
Inventor: NAKANE IZUMI
IPC: C08L57/00
Filed: 1996-08-07
Granted: 1999-09-30
Abstract: A resin composition comprising a polyolefin resin, a pigment and a copolymer resin obtainable from a monomer having an  alpha , beta -unsaturated double bond and a dibasic acid having an unsaturated double bond or an anhydride thereof is useful for preparing a molded article, such as a water-supply pipe. Dot-like projections and small-diameter blisters are not formed on the surface of the molded article when the surface is brought into contact with chlorine-containing water.
Patent DE-69605831-T2 (DE)
Inventor: VAN ERDEN DONALD
IPC: B65B9/20
Filed: 1996-02-22
Granted: 2000-06-29
Abstract: The present invention relates to a zipper for a reclosable bag or package comprising a male zipper profile (44) and a female zipper profile (46); said male zipper profile (44) having a male interlocking member (48), a web (56) extending laterally therefrom; and said female zipper profile (46) having a female interlocking member (52) adapted for snapping engagement with said male interlocking member (48), a web (56) extending laterally therefrom in the same direction as that in which said web extends from said male interlocking member, wherein a zipper guiding rail (62) extends from behind and in a direction opposite to at least one of said male and female interlocking members (48,52) on said male and female zipper profiles (44, 46). <IMAGE>
Patent DE-69622327-T2 (DE)
Inventor: MAILLET JEROME
IPC: C08L95/00
Filed: 1996-01-30
Granted: 2003-02-27
Abstract: PCT No. PCT/FR96/00159 Sec. 371 Date Dec. 13, 1996 Sec. 102(e) Date Dec. 13, 1996 PCT Filed Jan. 20, 1996 PCT Pub. No. WO96/23840 PCT Pub. Date Aug. 8, 1996The invention relates to improved bitumen compositions including: (A) 100 parts of bitumen (B) 0.1 to 10 parts of a copolymer of an alpha-olefin, of an unsaturated epoxide and of an ester of unsaturated carboxylic acid (C) 0.1 to 10 parts of a copolymer of an alpha-olefin and of an ester of unsaturated carboxylic acid, (D) 0 to 10 parts of a thermoplastic elastomer (E) 0 to 10 parts of a polymer which is reactive with (B) (F) 0 to 10 parts of an ethylene/vinyl acetate copolymer. These bitumens are stable when stored and resist rutting.
Patent DE-69624045-T2 (DE)
Inventor: WILLIAMS DAVID
IPC: A47B13/00
Filed: 1996-07-10
Granted: 2003-02-06
Abstract: A mounting mechanism (5) comprising: a first catch (15A) movable between an engaged position in which the first catch (15A) is engagable with a furniture part (2) to retain the furniture part (2) and a release position in which the first catch (15A) is releasable from the furniture part (2); a second catch (15) moveable between an engaged position in which the second catch (15) is engagable with another furniture part or the same furniture part (2) to retain that furniture part and a release position in which the second catch (15) is releasable from that furniture part (2); and a locking mechanism (22) to lock the second catch (15) being lockable in the release position. <IMAGE>
Patent DE-69624437-T2 (DE)
Inventor: KONNO YASUO
IPC: C07F9/6512
Filed: 1996-04-12
Granted: 2003-08-07
Abstract: Described are a 4,6-diarylpyrimidine derivative represented by the following formula (1): <CHEM> wherein R represents a heterocyclic ring which may be substituted by one to four lower alkyl groups or an amino group and Ar represents a phenyl, naphthyl or aromatic heterocyclic group which may have one to four substituents, and a salt thereof; a preparation process therefor; and a pharmaceutical containing it as an effective ingredient. It has excellent neovascular inhibitory action and is useful as a therapeutic agent for solid cancer, rheumatism, diabetic retinopathy or psoriasis.
Patent DE-69625819-T2 (DE)
Inventor: RICE PETER
IPC: A61P21/00
Filed: 1996-09-16
Granted: 2003-11-06
Abstract: The invention provides the use of a 5-HT3 receptor antagonist or a pharmaceutically acceptable derivative thereof for use in the treatment of dyskinesia.
Patent DE-69626687-T2 (DE)
Inventor: FRANKE ERIK
IPC: D06Q1/12
Filed: 1996-12-16
Granted: 2004-01-15
Abstract: A transfer capable of applying one- or multi-colored patterns to textiles under heat and pressure comprises a carrier sheet ( 1 ) having a non-binding surface which carries (a) a one- or multi-colored pattern ( 5 ) printed on the carrier sheet using a digitally controlled color printer; (b) a transparent ( 6 ) or white-pigmented ( 7 ) elastomer layer of a polymer having a high plasticizing point printed configuratively on the pattern ( 5 ); and (c) a heat-activatable thermoplastic polymeric glue layer ( 8 ) printed configuratively on the transparent ( 6 ) or white-pigmented ( 7 ) elastomer layer or a heat-activatable hot melt granulate sprinkled on the elastomer layer while said layer was still wet. An even better encapsulation of the colored pattern is obtained when the carrier sheet has printed thereon a first transparent elastomer layer of a polymer having a high plasticizing point, and the pattern is printed on this elastomer layer using a digitally controlled color printer. Additional strength is obtained when both a transparent elastomer layer and a white-pigmented elastomer layer are printed on top of the colored pattern.
Patent DE-69634776-T2 (DE)
Inventor: WECHTER J
IPC: A61P3/02
Filed: 1996-03-13
Granted: 2006-05-11
Abstract: A composition for use in preventing colorectal cancer and other neoplastic diseases includes an enantiomerically stable R-NSAID or a pharmaceutically acceptable salt thereof in an amount effective to elicit a chemoprotective effect. The composition is substantially free of the S-enantiomer of the R-NSAID. Therapeutic use of the composition is accompanied by reduced adverse side effects.
Patent DE-69710879-T2 (DE)
Inventor: SALIN-DROUIN DOMINIQUE
IPC: A61K47/32
Filed: 1997-04-04
Granted: 2002-11-14
Abstract: PCT No. PCT/FR97/00612 Sec. 371 Date Sep. 28, 1998 Sec. 102(e) Date Sep. 28, 1998 PCT Filed Apr. 4, 1997 PCT Pub. No. WO97/37642 PCT Pub. Date Oct. 16, 1997A medicament consisting of a biological medium-soluble capsule containing a micronised progesterone suspended in oil is disclosed, characterised in that the capsule also contains estradiol enclosed in microspheres, also suspended in oil, and which consist of one or more polymers that do not dissolve in oil but that dissolve in a biological medium.
Patent DE-69711677-T2 (DE)
Inventor: BARRON H
IPC: B29B11/16
Filed: 1997-11-13
Granted: 2002-07-18
Abstract: An improvement in the preparation of fiber preforms in which binder and fibers are dispersed to contact on vacuum-supplied screens is disclosed, comprising particularly (a) selecting a particulate binder material which is solid at 25 DEG  C; (b) heating the binder material, during initial contact with the fibers, to a viscosity and for a time which is the same as or proportional to 1,000 centipoise for one second; and (c) dispersing the binder material and the fibers such that the preform exhibits a variation in the ratio of fibers and binder which correlates to a coefficient of variation which is less than or equal to about 5 percent. The resulting preform shows superior compaction and uniformity of constitution even when it is prepared in sections or in asymmetric configurations. A wide variety of binders can be used, including thermoplastic and thermoset polymers, glasses, ceramics, metals, and the like, and the binder can also be selected from multi-component systems which are reactive with one another, such as epoxy-based systems, and/or reactive with a resin impregnant which may be subsequently introduced. In an alternative embodiment the preforms can be heated and pressed to make final composite articles, with or without direct application of a molding resin.
Patent DE-69712764-T2 (DE)
Inventor: LAMING RICHARD IAN
IPC: H04B10/18
Filed: 1997-08-04
Granted: 2003-01-02
Abstract: A method of fabricating an optical waveguide grating having a plurality of grating lines of refractive index variation comprises the steps of: (i) repeatedly exposing a spatially periodic writing light pattern onto a photosensitive optical waveguide: and (ii) moving the writing light pattern and/or the waveguide between successive exposures of the writing light pattern, so that each of at least a majority of the grating lines is generated by at least two exposures to different respective regions of the writing light pattern.
Patent DE-69808615-T2 (DE)
Inventor: KOPELMAN AVI
IPC: G06T19/20
Filed: 1998-05-19
Granted: 2003-09-11
Abstract: In a computer system that includes a Central Processing Unit and an associated input device, storage device and display device, a method for displaying on the display device a virtual three-dimensional (3D) dental model at desired preset views, for orthodontic use. The virtual 3D dental model is stored on the storage device and is indicative of a 3D structure of an individual's dental arches. The method includes the steps of providing a graphic user interface (GUI) that includes a graphic representation of the dental model and a plurality of graphic symbols each representative of a desired pre-set view of the dental model from a desired direction. Selecting through the input device graphic symbol from among the plurality of graphic symbols. Moving the dental model to a pre-set view which corresponds to the graphic symbol, whilst retaining the model in zoom.
Patent DE-69813016-T2 (DE)
Inventor: BUSCHERINI ROBERTO
IPC: B65B11/04
Filed: 1998-12-04
Granted: 2004-03-11
Abstract: In wrapping palletized loads with stretchable film having an elastic memory, when the wrapping is about completed, a distancing device is placed close to the wrapped load on which the last wrapping turn rests, so that a pocket is formed in the turn. The carriage of the wrapping machine is stopped in a predetermined angular position and the film tail is aligned and placed in a main clamp and a secondary clamp. Subsequently, a cutting device cuts the film between the two clamps, and the main clamp holding the leading end coming from the wrapping machine carriage moves backward at rest. The other clamp holding the tail end is introduced into the pocket and then opens and is drawn out from the pocket together with the distancing device , so that the wrapping tail gets caught and blocked by friction in the last turn which shrinks flat.
Patent DE-69815898-T2 (DE)
Inventor: BOWMAN DWAYNE
IPC: G06Q30/08
Filed: 1998-12-18
Granted: 2003-12-18
Abstract: The present invention provides a software facility for identifying the items most relevant to a current query based on items selected in connection with similar queries. In preferred embodiments of the invention, the facility receives a query specifying one or more query terms. In response, the facility generates a query result identifying a plurality of items that satisfy the query. The facility then produces a ranking value for at least a portion of the items identified in the query result by combining the relative frequencies with which users selected that item from the query results generated from queries specifying each of the terms specified by the query. The facility identifies as most relevant those items having the highest ranking values.
Patent DE-69816016-T2 (DE)
Inventor: MERINO LOPEZ JOSE
IPC: B29L30/00
Filed: 1998-12-11
Granted: 2004-04-22
Abstract: The mold employs an insert with two types of section, one forming a support, another keying with it. When positioned on a section of the tire mold, the support projects from it. When located for molding, each key is assembled in its support. The mold is closed and the tread is molded. The keys are then extracted from the support(s). Finally, mold sections are retracted to the open position to extract the support(s). Independent claims are included for: the tire tread, made as described; the mold used, and the mold insert (10). Each key (16, 17) part-delimits an opening (20-23) of the insert. Each can be moved in a direction other than that of mold (11) opening or closing. The arrangement allows removal of the insert from the mold, without damaging the molding produced. Other preferred features of the insert are detailed. Preferred features: In the method, each key to be freed from its support in the molding insert, is moved in a direction differing from that of opening/closing of the mold section carrying the insert.
Patent DE-69827215-T2 (DE)
Inventor: ALLEGRI PRIMO
IPC: B01D29/64
Filed: 1998-09-30
Granted: 2006-02-16
Abstract: The invention falls within the sector of static filtration plants for liquids. A plurality of frames (4), each of which contains filtering walls (5), is fixed to the inside walls of a tank (1). The liquid to be clarified, which is present in a plurality of sectors (10) of the internal volume of the tank (1), crosses the said filtering walls, passing, clarified, into a plurality of sectors (9) which are intercalated with the former, each of said sectors (9) being in the form of a closed compartment. <IMAGE>
Patent DE-69834130-T2 (DE)
Inventor: DAUVRIN THIERRY
IPC: C12R1/865
Filed: 1998-10-23
Granted: 2006-12-21
Abstract: The present invention is related to an isolated and purified nucleotidic sequence from microbial origin, encoding an epoxide hydrolase, the vector comprising said nucleotidic sequence, the recombinant host cell transformed by said nucleotidic sequence and the epoxide hydrolase amino acid sequence encoded by said nucleotidic sequence and/or expressed by said recombinant host cell. <IMAGE>
Patent DE-69902720-T2 (DE)
Inventor: GUEST PHILIP JOHN
IPC: B60T8/86
Filed: 1999-06-11
Granted: 2003-04-30
Abstract: An automatic brake control system for a vehicle in which the brakes 16, 17 are controlled by a control unit 22 to limit vehicle speed when descending a hill is provided with an input from a sensor on the gear selector 28. The control unit has a vehicle speed characteristic associated with each gear, the characteristics relating vehicle speed as controlled by the brake system to position of the accelerator pedal, and having a different minimum speed for each gear. <IMAGE>
Patent DE-69905793-T2 (DE)
Inventor: FOUACHE CATHERINE
IPC: C07H3/04
Filed: 1999-05-10
Granted: 2004-03-18
Abstract: The crystallization of maltulose (4-O- alpha -D-glucopyranosyl-D-fructose) monohydrate comprises cooling of the supersaturated maltulose solution. The crystallization of maltulose monohydrate comprises: (1) preparing an aqueous solution containing maltulose (65 wt. %); (2) concentrating the aqueous solution to obtain a solid content of more than 50 wt. % and a supersaturation degree lower than 1; (3) cooling the solution to obtain a supersaturation degree greater than 1; (4) crystallizing maltulose in the solution while cooling at controlled speed and stirring; and (5) separating, collecting and drying the crystals of maltulose monohydrate.
Patent DE-69907212-T2 (DE)
Inventor: GUITONEAU EDWARD
IPC: F16L21/06
Filed: 1999-08-19
Granted: 2004-03-04
Abstract: Two pipe sections (1-4, 31, 32) of a high-pressure line each comprise a fluid-tight inner jacket (9) made of a thermoplastic material and a reinforced outer jacket (10). The innner jackets are attached to one another by means of a fluid-tight weld (5-8, 33) and the outer jackets are each connected to one another by means of a connecting sleeve (16, 17, 25, 26). The connecting sleeve comprises shells which have serrations (15, 27) on the inside, as well as clamping means (13, 14, 28-31) for clamping the shells on the pipe sections in such a way that the internal serrations (18, 27) are made to interact with the outer jackets of the pipe sections.
Patent DE-69907821-T2 (DE)
Inventor: JARVINEN JOUKO
IPC: C03B27/044
Filed: 1999-07-22
Granted: 2004-02-26
Abstract: A machine (10) particularly for curving and tempering glass plates, comprising, on a supporting footing (11) with a motorized roller table for conveying the plates (14) being treated, an articulated retractable roller conveyor (12) whose sides (13) are perpendicular to an advancement direction of the plates (14) being treated, each side being formed by a catenary which is constituted by series of plate-like elements which mutually mesh by means of corresponding cogged ends and is associated with lifting actuators (16) at its ends (15), the retractable roller conveyor (12) supporting first nozzles (25) which are rigidly coupled thereto and are connected to a forced air supply system and being associated with translatory motion actuators (17) for the plates conveyed thereon, a liftable structure (26) being arranged above the retractable roller conveyor (12), being articulated complementarily to the roller conveyor and supporting second nozzles (27) which are connected to the forced air supply system. <IMAGE>
Patent DE-69919841-T2 (DE)
Inventor: SCOTT R
IPC: A61N1/30
Filed: 1999-01-28
Granted: 2005-09-22
Abstract: The present invention relates generally to improved cathodes (24) for use in an electrotransport device (10) for transdermally or transmucosally delivering a beneficial agent (e.g., a drug) to, or extracting a body analyte (e.g., glucose) from, the body surface of a patient. Most particularly, the present invention relates to a cathodic electrode (24) in the form of a silver halide foil which can be made, e.g., by forging particulate silver chloride. The cathode (24) does not absorb agent (e.g., drug), eliminates the need for binders, solvents and processing aids during the manufacturing process, and increases dimensional freedom of design.
Patent DE-69928226-T2 (DE)
Inventor: LULY R
IPC: A61K31/451
Filed: 1999-01-21
Granted: 2006-07-13
Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by the following structural formula:and physiologically acceptable salts thereof.
Patent HU-E026429-T2 (HU)
Title: 2-(2,4,5-substituted-anilino) pyrimidine derivatives as egfr modulators useful for treating cancer
Inventor: BUTTERWORTH SAM
IPC: A61P35/00
Filed: 2012-07-25
Abstract: The present invention relates to certain 2-(2,4,5-substituted-anilino)pyrimidine compounds and pharmaceutically acceptable salts thereof which may be useful in the treatment or prevention of a disease or medical condition mediated through certain mutated forms of epidermal growth factor receptor (for example the L858R activating mutant, the Exon19 deletion activating mutant and the T790M resistance mutant). Such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers. The invention also relates to pharmaceutical compositions comprising said compounds and salts thereof, especially useful polymorphic forms of these compounds and salts, intermediates useful in the manufacture of said compounds and to methods of treatment of diseases mediated by various different forms of EGFR using said compounds and salts thereof.
Patent TR-200000266-T2 (TR)
Title: Antimetastaz maddeler olarak faydalı oligo-tiofenler, bunların ve bunları ihtiva eden farmasötik bileşimlerin hazırlanması.
Inventor: DOMENICO ROBERTO DI
IPC: A61K31/405
Filed: 1998-07-28
Abstract: Mevcut bulus istege bagli olarak dogal veya sentetik aminoasitlere baglanan oligotiofenlere iliskin bir bulustur. Bu bilesiklerin uPA-uPAR antagonist etkinlige sahip olduklari ve antitümör ve/veya antimetastaz özellikli maddeler olarak kullanilabildikleri bulunmustur.
Patent TR-200200146-T2 (TR)
Inventor: YEAGER JAMES L
IPC: A61K47/18
Filed: 1999-05-13
Abstract: A topical composition of a semi-solid consistency suitable is provided for transdermal application of prostaglandin E1. The composition comprises prostaglandin E1, a penetration enhancer, a polysaccharide gum, a lipophilic compound, and an acidic buffer system. The penetration enhancer is an alkyl-2-(N,N-disubstituted amino)-alkanoate ester, an (N,N-disubstituted amino)-alkanol alkanoate, or a mixture of these. The lipophilic compound may be an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, or a mixture of these. The composition includes a buffer system capable of providing a buffered pH value for said composition in the range of about 3 to about 7.4.
Patent TR-200201423-T2 (TR)
Title: Birleştirilmiş bir iyon değişimi ve kristalizasyon prosesi ile iki alkali metal tuzunun üretimi.
Inventor: MATHIESEN FLEMMING
IPC: C01B25/30
Filed: 2000-12-01
Abstract: Bu bulus, iyon degisimi ve kristalizasyon asamalarini kapsayan, ayni proseste  potasyum nitrat ve fosfat gibi bir alkali metal nitrat ve fosfat üretimine yönelik bir proses ile ilgilidir. Üretilen tuzlar özellikle gübrelerin sik sik sulama yöntemleri ile uygulandigi bahçecilikte gübre olarak faydalidir. Bu bulusun önerdigi proses asagidaki birim islemleri kapsamaktadir: eritme, iyon degisimi, nötürlestirme, kati maddelerin ayrilmasi, konsantrasyon ve kristalizasyon.
Patent DE-602004001451-T2 (DE)
Inventor: MARCHESE PAOLO
IPC: F04D29/44
Filed: 2004-05-18
Granted: 2007-02-08
Abstract: There is described an automotive compressor (1) having a casing (8) defining an intake section (11) for a fluid for compression, and a delivery section (15) for delivering the compressed fluid; an impeller (3) movable angularly inside the casing (8) to increase the pressure of the fluid; and distributing means (22) carried by the intake section (11) of the casing (8) to conduct the fluid for compression to the impeller (3); the casing (8) and the distributing means (22) being defined by separate members connected releasably to each other. <IMAGE>
Patent DE-602004002615-T2 (DE)
Inventor: LANNI THOMAS W
IPC: H02M1/00
Filed: 2004-05-07
Granted: 2007-08-16
Abstract: A cradle casing has a DC/DC adapter to receive DC power from a DC power source and generate a first DC power signal. A sleeve accepts an AC/DC adapter, and guides movement of the AC/DC adapter when the AC/DC adapter is inserted into the cradle casing. The AC/DC adapter is capable of receiving AC power from an AC power source and generating a second DC power signal. A circuit receives at least one of the first DC power signal and the second DC power signal and outputs a third DC power signal. <IMAGE>
Patent DE-602004004564-T2 (DE)
Inventor: HURWICZ MAXIM DANIEL
IPC: G10G7/00
Filed: 2004-04-01
Granted: 2007-10-25
Abstract: An electronic tuner (2) for tuning a musical instrument has a tuner housing (4) in which an electronic circuitry for tuning the instrument is situated, and a multi-positional and multi-functional bracket (6) which is reciprocatingly slidable and pivotally mounted on the tuner housing (4). The bracket (6) is positionable in a closed position, where it rests closely against the tuner housing (4), as a stand, where it supports the electronic tuner (2) in an upright or a slightly angled position, and in a position where the electronic tuner may be suspended from the musical instrument being tuned. <IMAGE>