baber/WOPTO huggingface dataset:
Patent CA-2651456-A1 (CA)
Inventor: NETT JUERGEN
IPC: C12N15/63
Filed: 2007-05-18
Abstract: Methods and materials are provided for integrating heterologous nucleic acids into the genome of a cell or virus without disrupting expression of genes adjacent to the insertion site.
Patent CA-2653777-A1 (CA)
Title: 2-anilino-4-(heterocyclic)amino-pyrimidines
Inventor: HUNTER JACK A
IPC: C07D417/12
Filed: 2007-06-13
Abstract: The present invention relates to 2-arylamino-4-(heterocyclic)aminopyrimidines inhibitors which are inhibitors and therefore inhibit Protein Kinase C-alpha (PKC-a). The PKC-a inhibitors of the present invention are important for improving myocardial intracellular calcium cycling, resulting in improved myocardial contraction and relaxation performance and thereby slowing the progression of heart failure. The present invention further relates to compositions comprising said 2-arylamino-4-(heterocyclic)amino-pyrimidines and to methods for controlling, abating, or otherwise slowing the progression of heart failure.
Patent CA-2655090-A1 (CA)
Title: New supported oxidation reactants, process for their preparation and uses thereof
Inventor: CANTEL SONIA
IPC: C07K1/113
Filed: 2007-06-14
Abstract: The present invention relates to a supported oxidation reactant of formula (I): R-[Met(O)k]n-X- (I) in which: - R represents a hydrogen atom or an amine function-protecting group, -[Met(O)] represents an oxidized methionine residue of formula - k is 1 or 2 - represents a solid or soluble support used in organic synthesis, - X represents a radical derived from a function of the type amine or hydroxyl, or halogeno, capable of anchoring methionine, it being understood that this function capable of anchoring methionine can be separated from the support by means of a functionalized arm or a spacer, and - n is an integer greater than or equal to 1. The invention also relates to the use of a supported oxidation reactant of formula (I), for the formation of intramolecular disulfide bridges, in particular in peptides and/or proteins.
Patent CA-2656838-A1 (CA)
Inventor: LABRIE FERNAND
IPC: C12Q1/34
Filed: 2007-07-18
Abstract: L'invention concerne une mthode in vitro de criblage de composs candida ts pour le traitement prventif ou curatif de l'acn, comprenant la dtermin ation de la capacit d'un compos 
 moduler l'expression ou l'activit du tr ansporteur 1 membranaire du proxisome contenant un site de liaison 
 l'ATP du type 3 de la sous-famille D (ABCD3), ainsi que l'utilisation de modulateu rs de l'expression ou de l'activit de ce transporteur pour le traitement de l'acn ou des dsordres cutans associs 
 une hypersborrhe. L'invention concerne aussi des mthodes de diagnostic ou pronostic in vitro de ces patho logies.
Patent CA-2661614-A1 (CA)
Title: Wheeled mobile caddy
Inventor: THIBAULT RICHARD R
IPC: B25H3/00
Filed: 2007-08-27
Abstract: The invention is a combination mobile tool caddy and seat for performing work adapted for use by a tradesman such as an electrician, plumber, carpenter and the like. The wheeled mobile caddy includes a rigid frame having a lower and an upper support member vertically separated by upright corner members. The lower support member extends beyond the upper support member to form a platform area upon which a cylindrical vessel or bucket can be stored. The bucket is equipped with a liner having pockets for storing hand tools. Four caster wheels are appropriately attached to the lower support member so that the caddy can be wheeled from a service vehicle to a specific job site having stored therein the tradesman's tools, as well as necessary material supplies to perform daily job functions.
Patent CA-2661842-A1 (CA)
Title: Tricyclic heteroaryl compounds and their use as serine-threonine protein kinases and parp modulators
Inventor: CHUA PETER C
IPC: C07D221/22
Filed: 2007-08-31
Abstract: The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate casein kinase (CK) activity and/or poly(ADP-ribose)polymerase (PARP) activity. The invention also relates in part to methods for using such molecules. The claimed invention relates to compounds of the following formula: (see above formula)
Patent CA-2663515-A1 (CA)
Inventor: GOLINSKI MIROSLAW JERZY
IPC: C07D489/02
Filed: 2007-09-24
Abstract: Described herein are prodrugs of the opioid buprenorphine, methods of making them, formulations comprising these prodrugs, and methods of using them. One embodiment described herein relates to the transdermal administration of a buprenorphine prodrug in an abuse-resistant formulation for treating and preventing diseases and/or disorders.
Patent CA-2668875-A1 (CA)
Title: Configurations and methods for gas condensate separation from high-pressure hydrocarbon mixtures
Inventor: MAK JOHN
IPC: B01D47/00
Filed: 2007-11-06
Abstract: Contemplated configurations and methods for gas processing use a refluxed absorber that receives a liquid and a vapor hydrocarbon feed. The absorber further receives a stripping medium that is at least in part formed from a vapor portion of a stabilizer overhead and also receives a scrubbing medium that is at least in part formed from a liquid portion of the stabilizer overhead. Most preferably, the absorber overhead is maintained at a temperature near or even below the hydrate point of the feed.
Patent CA-2669147-A1 (CA)
Inventor: MENDES FLAVIA DUTRA
IPC: C22B23/00
Filed: 2007-11-12
Abstract: The process, according to the invention, comprises the following stages: (a) processing (1) of the laterite ore (O) by crushing, scrubbing, attrition, separation, and high-intensity magnetic separation; (b) Leaching (2) of the non-magnetic fraction (CN) obtained form the previous stage (a); (c) optionally, neutralization (3) of the effluent from the leaching and/or solid-liquid separation stages (4); (d) treatment of the effluents from stages (b) or (c) using an ion-exchange hybrid system (5) comprising at least one circuit for removal of impurities and at least one circuit for recovery of nickel and cobalt; (e) elution (6) of the ion-exchange resin used; (f) separation, purification, and recovery (7) of the nickel and cobalt.
Patent CA-2669278-A1 (CA)
Inventor: GOLDEN DUANE
IPC: F16D15/00
Filed: 2007-10-24
Abstract: A mechanism with an inner race, which has cams, an outer race and rollers between the cams and the outer race. The inner race has a first notch while the outer race has a second notch with a narrow portion and a wider portion. A member is disposed in the first and second notches. Positioning of the member in the first notch and the narrow portion of the second notch inhibits relative rotation between the inner and outer races and power is not transmitted between the outer race and a power transmitting member, such as a gear. Positioning of the member in the first notch and the wider portion of the second notch permits some relative rotation between the inner and outer races to cause the cams to urge the rollers outwardly so that the outer race frictionally engages the power transmitting member to facilitate transmission of rotary power therebetween.
Patent CA-2670168-A1 (CA)
Title: Amino quinazolines derivatives wuth blood platelet reducing properties
Inventor: FRANKLIN RICHARD
IPC: A61K31/517
Filed: 2007-11-19
Abstract: This invention relates to the discovery of prodrugs of 3-or 5-substituted analogues of the selective platelet lowering agent anagrelide which have reduced potential for cardiovascular side-effects and which should therefore lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to prodrugs of certain imidazoquinazoline derivatives which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting the formation of blood platelet.
Patent CA-2671867-A1 (CA)
Inventor: THOLOMIER DAMIEN
IPC: H02H7/22
Filed: 2006-12-14
Abstract: In the field of three-phase electrical power systems there is a need for an improved method and apparatus for protecting a bus which obviate the problems associated with conventional bus protection schemes. A method of protecting a bus (16) in a three-phase electrical power system comprises the steps of (a) sampling voltage values and current values of each phase of the or each power system element (14) within a predefined protection zone; (b) analysing at least one sampled voltage value of each phase of a power system element (14) within the protection zone to detect when a fault condition arises; (c) on detection of a fault condition, determining whether the fault condition has arisen because of a bus fault; and (d) electrically isolating the bus (16) from the or each power system element (14) within the protection zone when a bus fault is determined so as to clear the bus fault.
Patent CA-2674594-A1 (CA)
Inventor: ZHOU SHUNXIN
IPC: H02P27/05
Filed: 2009-08-04
Abstract: The present invention discloses a system for realizing rotor variable frequency speed control asynchronously and simultaneously by driving multiple motors via one inverter, which consists of a motor group, a rectifier group, a chopper group, an isolator group, an amperite group, a power capacitor group, a full bridge or a half bridge, a speed feedback voltage detector group and a current feedback voltage detector group.  By employing inversion control theory, the voltage outputs by a full-bridge inverter or a half-bridge inverter is taken as an additional inverse electromotive force of each functional motor according to the rated power of the motor, and each motor is made to operate asynchronously and simultaneously by the work of each chopper, thereby the operations of a crane, lifting, luffing, revolving and walking, can be realized. During the rising of the crane, redundant electric energy will always be fed back to the motor via an inverter; and during the falling of the crane, the motor will be in electricity generating state, and the electric energy generated will be fed back to the motor via the inverter, thus energy recovery may be realized. The invention has such characteristics as simple circuit, small size, low cost, high reliability and energy saving.
Patent CA-2677035-A1 (CA)
Title: Method and apparatus for paging group handling
Inventor: WANG PETER S
IPC: H04W68/02
Filed: 2008-01-31
Abstract: A method and apparatus for paging group handling includes grouping wireless transmit/receive units (WTRUs) into a paging group. The paging group is assigned a paging occasion, and an existence of a page is indicated to the WTRUs.
Patent CA-2677740-A1 (CA)
Inventor: SATO YOSHIAKI
IPC: A63B21/065
Filed: 2007-12-26
Abstract: The efficacy and safety of compression training are enhanced. The compression training system is one involving winding around a portion of the arms or legs to be tightened, comprising constriction device (100) with a gas bag; pressure regulation unit (200) capable of regulating a compression force to the tightened portion by the constriction device (100) through air supply to or air withdrawal from the gas bag of the constriction device (100); measuring unit (300) and control unit (400). The measuring unit (300) measures a measurement object value selected from among the pulse rate, brain wave record and oxygen saturation value of the person under compression training. The control unit (400), when the measurement object value measured by the measuring unit (300) indicates due discontinuation of compression training, sends the information to the pressure regulation unit (200) and discontinues the compression training.
Patent CA-2681055-A1 (CA)
Inventor: RAPPARINI GINO
IPC: B65B43/60
Filed: 2007-09-25
Abstract: Machine for packaging in capsules, also in a vacuum and/or in a controlled atmosphere, characterized by the fact that a cylindrical wheel (G) with horizontal axis (R), peripherally provided with rows (S) of cavities (A), parallel to said axis (R) and angularly equally distanced by the step (P), preset to be interchangeably equipped with moulds (F,- F') having different formats and geometrically congruent to the format of the capsules to be used (C; C).
Patent CA-2681472-A1 (CA)
Inventor: SMITH IVAN R
IPC: B22F3/00
Filed: 2008-03-19
Abstract: A fishing lure (10) manufactured from a sintered metal powder. The metal powder may be one or more metals, one or more alloys, or any combination or mixture thereof. The lure (10) is of a weight sufficient to sink to a depth in the water and shaped such that, when urged through the water, the lure (10) moves in a substantially oscillating motion. A method of manufacturing a fishing lure (10) is also disclosed.
Patent CA-2684661-A1 (CA)
Inventor: ROUSSEAU FRANCIS
IPC: C12Q1/68
Filed: 2008-04-30
Abstract: The present invention relates to a diagnostic method of determining whether a subject, preferably an obese subject, is at risk of developing type 2 diabetes or diabetic complications, which method comprises detecting the presence of an alteration in the EEFSEC gene locus in a biological sample of said subject.
Patent CA-2687526-A1 (CA)
Inventor: HELFRICH FELIX CASPAR
IPC: B29C48/76
Filed: 2008-06-05
Abstract: The present invention provides a connecting device (100).for connecting an unhardened fibre layer (104) which is arranged on a surface section (112) of a fibre compound structure (102) to the fibre compound structure. The connecting device comprises pressure cushion (390) comprising a pressure cap (120,308) for being arranged above the surface section and a pressure tight cap mat (106) which is pressure tightly connected to a circumferential border (107) of the pressure cap, thereby forming a pressure area which is limited by the pressure cap and. by the cap mat. The connecting device further comprises a pressure inducing means (302) for inducing an overpressure which presses the cap mat against the fibre layer into the pressure area. According to a further aspect the invention provides a processing method for processing a fibre compound structure.
Patent CA-2688140-A1 (CA)
Inventor: GUNZEL EDWARD
IPC: D04H3/14
Filed: 2008-05-22
Abstract: Laminates suitable for constructing waterproof and breathable articles such as protective clothing which are both comfortable and exhibit enhanced resistance to fire are described. Particularly, flame resistant laminate constructions are described comprising a meltable textile as the outermost layer laminated to an intermediate protective layer comprising a waterproof film laminated to an innermost fabric layer comprising a thermally stable textile. Laminate constructions of the present invention exhibit breathability on the order of at least 1000 MVTR, a water entry pressure of at least 0.5 psi and have a horizontal flame break open time of at least 10 seconds.
Patent CA-2688704-A1 (CA)
Title: Sealing method and apparatus
Inventor: EDEN ROBERT D
IPC: E21B33/13
Filed: 2009-12-15
Abstract: According to the present invention there is provided an apparatus for forming a plug in a passageway, the apparatus comprising a carrier which in use is lowered into the passageway, the carrier comprising an elongate body of a material resistant to creep which supports first and second spaced apart portions that are a sliding fit in the passageway; a body of material supported on the carrier, said material having a melting point which is higher than the temperature within the passageway and which expands as it solidifies; and a removable heater operative to melt the body of material such that melted material fills a space defined between the first and second portions.
Patent CA-2690112-A1 (CA)
Title: Method of joining a conference call
Inventor: LOGAN ADRIAN
IPC: H04M1/72469
Filed: 2010-01-14
Abstract: In a computer-implemented method of joining a user to a conference call event an interface associated with a time management software application is displayed. The interface displays information relating to the conference call event including a date for a conference call which is subject of the conference call event and a start time of the conference call. While displaying the interface, a menu offering one or more options is displayed; these one or more options include an option to join the conference call. When an indication of a selection of the option to join the conference call is received, information associated with the conference call is located; this information includes a telephone number for a conference call bridge. A connection with the conference call bridge using the telephone number is initiated.
Patent CA-2690959-A1 (CA)
Inventor: KUHNKE JOACHIM
IPC: A61K31/56
Filed: 2008-06-04
Abstract: The 17.beta.-cyano-19-nor-androst-4-ene deriva-tives of the present invention have gestagenic activity. They have the general chemical formula (1), in which Z is selected from the group comprising O, two hydrogen atoms, NOR and NNHSO2R, wherein R is hydrogen or C1-C4 alkyl, R4 is hydro-gen or halogen and in addition either: R6a, R6b together form methylene or 1,2 ethanediyl or R6a is hydrogen and R6b is se-lected from the group comprising hydrogen, methyl and hy-droxymethylene, and R7 is selected from the group compris-ing hydrogen, C1-C4 alkyl, C2-C3 alkenyl and cyclopropyl, or:  R6a is hydrogen and R6b and R7 together form methylene, or are omitted, whereby a double bond is formed between C6 and C7, R9 and R10 are hydrogen, or are omitted, whereby a double bond is formed between C9 and C10, R15 and R16 are hydro-gen or together form methylene, R17 is selected from the group comprising hydrogen, C1-C4 alkyl and aIIyI, at least one of the substituents R4, R6a, R6b, R7, R15, R16 and R17 not being hydro-gen, or R6b and R7 being omitted, whereby a double bond is formed between C6 and C7. The derivatives also comprise the solvates, hydrates, stereoisomers, diastereomers, enantiomers and salts of the aforementioned substances.
Patent CA-2691232-A1 (CA)
Inventor: PIANO CHANTHASENG
IPC: B01D46/00
Filed: 2010-01-27
Abstract: A filter cover for attachment to a register or duct terminal in HVAC applications which allows for simple enhancement of air filtration in the forced air environment. A selected filter media is dimensionally sized to correspond to the outer dimension of the register, and includes adhesive or another removable attachment which allows for its attachment along substantially all of its edges to the register. When the filter media is expended, the cover can be replaced. The method of use of the product is also outlined.
Patent CA-2691736-A1 (CA)
Title: Combination of 6-(3-chloro-2-fluorobenzyl)-1-[(2s)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid and lopinavir for the treatment of a viral infection in a human
Inventor: KEARNEY BRIAN P
IPC: A61K38/06
Filed: 2008-06-26
Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by coadministering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with lopinavir or a pharmaceutically acceptable salt thereof.
Patent CA-2692570-A1 (CA)
Inventor: SURGULADZE BESIKI
IPC: A61B17/00
Filed: 2010-03-05
Abstract: A method of diagnosis and treatment of malignant tumours by the steps locating an area containing of lymph systems including lymph nodes and lymph ducts draining the area around a tumour, injecting a magnetic particles containing marker compound in and around the tumour, the compound migrating into the lymph system and lymph nodes draining the area around said tumour; making images of such area, by methods such as X-ray, Ultrasound and the like and identifying locations of lymph nodes, conducting biopsies of lymph nodes responding to the marker compound to determine the tumour status of such lymph nodes, and operating to remove both the malignant tumour and tumour-invaded lymph nodes, and subsequently subjecting the area around said tumour and containing any remaining said lymph nodes and ducts to an hyperthermal treatment by an oscillating electromagnetic field thereby inducing heat in said magnetic particles containing marker compound, to break down any potentially remaining tumour cells in the said remained micro lymph nodes in that area. Also disclosed is a marker compound for the marking , detecting, and possible subsequent treatment of the lymph system draining the tumour area.
Patent CA-2692657-A1 (CA)
Inventor: CETTI JONATHAN ROBERT
IPC: A61K8/03
Filed: 2008-07-25
Abstract: The present invention relates to a personal care article that comprises a single chamber package and a liquid personal care product. The package comprises a dispensing orifice, a first zone proximate to the dispensing orifice and a second zone distal to the dispensing orifice. The liquid personal care product comprises a first personal care composition substantially disposed within the first zone and the second personal care composition substantially disposed within the second zone. The first composition comprises a first fragrance character and the second composition comprises a second fragrance character; wherein the first fragrance character is distinct from the second fragrance character.
Patent CA-2693029-A1 (CA)
Inventor: SKRIPKIN SERGEY
IPC: G01V1/30
Filed: 2010-02-16
Abstract: Embodiments of automated structural interpretation are described. In some embodiments, a method includes identifying one or more object points belonging to an object to be tracked; tracking a trajectory of the one or more object points, including: calculating a plurality of etalons around at least one of the one or more object points using one or more different angular parameters; selecting one or more candidate points for evaluation; extracting one or more samples from around the one or more candidate points; and evaluating a next trajectory location of the one or more object points based at least partially on the one or more samples and one or more of the plurality of etalons.
Patent CA-2693663-A1 (CA)
Inventor: FISCHER STEPHAN
IPC: A61K47/48
Filed: 2008-07-18
Abstract: The current invention is related to a conjugate comprising two or more antifusogenic peptides and an anti-CD4 antibody (mAb CD4) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said anti-CD4 antibody and to the pharmaceutical use of said conjugate.
Patent CA-2695148-A1 (CA)
Inventor: CHEN SHOUJUN
IPC: A01N43/78
Filed: 2008-07-31
Abstract: The invention relates to compounds that are useful as immunosuppressive agents and for treating and preventing Inflammatory conditions, allergic disorders, and immune disorders.
Patent CA-2695746-A1 (CA)
Inventor: BEAUPRE RICHARD ALFRED
IPC: B32B18/00
Filed: 2010-03-04
Abstract: A substrate (12) for power electronics (100) mounted thereon, comprises a middle ceramic layer (120) having a lower surface (124) and an upper surface (123), an upper metal layer (121) attached to the upper surface (124) of the middle ceramic layer (120), and a lower metal layer (122) attached to the lower surface (124) of the middle ceramic layer (120). The lower metal layer (122) has a plurality of millichannels (125, 126) configured to deliver a coolant for cooling the power electronics (100), wherein the millichannels (125, 126) are formed on the lower metal layer (122) prior to attachment to the lower surface (124) of the middle ceramic layer (120).  Methods for making a cooling device and an apparatus (10) are also presented.