baber/WOPTO huggingface dataset:
Patent AU-2018211351-B2 (AU)
Title: Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids
Inventor: BADIAVAS EVANGELOS V
IPC: A61P17/00
Filed: 2018-08-06
Granted: 2020-05-28
Abstract: Abstract The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supematants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.
Patent AU-2018256383-B2 (AU)
Title: Non-clogging dispensing device
Inventor: CAWTHON DUSTIN CHRISTOPHER
IPC: A61M5/19
Filed: 2018-04-18
Granted: 2023-06-01
Abstract: An assembly for mixing and dispensing a multi-component fluid includes a sheath having first and second fluid chambers, a chamber coupler, and a flexible tip. The chamber coupler forms first and second fluid channels. Additionally, the flexible tip forms a mixing chamber with a variable mixing volume and an outlet. The flexible tip is coupled to the chamber coupler near a distal end of the sheath. In the presence of an activation force, the flexible tip is forced out of the sheath and positioned in a dispensing state with a maximum mixing volume. In the absence of the activation force, the flexible tip is housed within the sheath and positioned in a non-dispensing state with a minimum mixing volume such that the outlet is substantially closed.
Patent AU-2018256494-B2 (AU)
Title: Method for the preparation of (1,2,4)-triazolo(4,3-A)pyridines
Inventor: BIO MATTHEW
IPC: C07D471/04
Filed: 2018-10-30
Granted: 2019-09-26
Abstract: Disclosed herein are methods for preparing [1,2,4]triazolo[4,3- a]pyridines, particularly ( R)-6 (1-(8-fluoro-6-(1-methyl-iH-pyrazol-4- yl)-[1,2,4]triazolo[4,3-alpyridin-3-yl)ethyl)-3-(2 methoxyethoxy)-1,6- naphthyridin-5(6H)-one, and precursors thereof, such as a method comprising reacting ( R)- N-(3-fluoro-5-(1methyl-IH-pyrazol-4-yl) pyridin-2-yl)-2-(3-(2 methoxyethoxy)-5-oxo-1,6-naphthyridin-6(5H)yl) propanehydrazide ("HYDZ"): (HYDZ) under conditions sufficient to form (R)-6-(i-(8-fluoro-6-(i-methyl- IH-pyrazol-4-yl) [1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2- methoxyethoxy)-1,6-naphthyridin-5(6H)-one ("A"): (A)
Patent AU-2018365717-B2 (AU)
Title: Magnetic field measuring element, magnetic field measuring device, and magnetic field measuring system
Inventor: TSUKAMOTO AKIRA
IPC: G01R33/035
Filed: 2018-10-29
Granted: 2021-11-04
Abstract: In order to lower a magnetic field measuring element in the height direction thereof while reducing interference, this magnetic field measuring element is characterized by comprising a Superconducting QUantum Interference Device (SQUID) magnetic sensor (1z), a SQUID magnetic sensor (1x) disposed either on a second plane which is perpendicular to a first plane including a coil surface of the SQUID magnetic sensor (1z) and which includes the center of the SQUID magnetic sensor (1z), or in the vicinity of the second plane, and a SQUID magnetic sensor (1y) disposed either on a third plane perpendicular to the first plane and the second plane, or in the vicinity of the third plane, wherein the center of the SQUID magnetic sensor (1x) is present either on a straight line which passes through the center of the SQUID magnetic sensor (1z) and is perpendicular to the first plane, or in the vicinity of said straight line, and the center of the SQUID magnetic sensor (1y) is present in a position displaced from a line joining the center of the SQUID magnetic sensor (1z) and the center of the SQUID magnetic sensor (1x).
Patent AU-2018377893-B2 (AU)
Title: Flexible laminate with improved integrated pressure-release valve
Inventor: HANSEN PETER
IPC: B32B27/08
Filed: 2018-11-22
Granted: 2023-11-30
Abstract: The present invention is related to flexible multilayer laminates having an improved integrated, one-way pressure-release valve for use in a sealed container for packing gas-producing products. The pressure-release valve is partly disconnected from the rest of the laminate, forming an inflatable outlet tube with at least one large outlet opening and lifting off from the laminate under increased pressure in the pack.The one- way pressure-release valve allows for pressure-release at low minimum opening pressure in a reliable and reproducible way.
Patent AU-2019201278-B2 (AU)
Title: Method and apparatus for identifying when an idividual is in proximity to an object
Inventor: HAKINS DAVID
IPC: G08B21/02
Filed: 2019-02-22
Granted: 2020-09-10
Abstract: An apparatus for identifying when an individual is in proximity to an 
object having a length has a sensor portion having a wire loop through which electric 
current runs and creates an electromagnetic field that emanates about the wire loop.  
The wire loop extending along at least a third of the length of the object. The 
apparatus has a personal alarm device that is worn by the individual which detects 
the presence of the magnetic field emanating from the wire loop when the personal 
alarm device is in the magnetic field and produces a signal indicating the personal 
alarm device is within the magnetic field. Alternatively, the sensor portion extends 
from a contiguous boundary up to 500 meters, where the boundary has a geometry 
that is linear or meandering. A head piece for an individual's head. A method for 
identifying when an individual is in proximity to an object. A field extension 
module. A proximity device.  
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Patent AU-2019203538-B2 (AU)
Title: Methods For Harvesting Mammalian Cell Cultures
Inventor: GOUDAR CHETAN
IPC: C12N5/00
Filed: 2019-05-20
Granted: 2020-10-08
Abstract: The invention provides methods and materials for culturing mammalian cells and 
harvesting recombinant protein.
Patent AU-2019204520-B2 (AU)
Title: Treatment of pelvic organ prolapse
Inventor: IGLESIAS RAMON JOSE
IPC: A61B5/103
Filed: 2019-06-26
Granted: 2020-09-03
Abstract: The present invention relates to the diagnosis and treatment of pelvic floor prolapse. The 
diagnosis and treatment may involve the use of a multiple sensor-enabled device for vaginal 
insertion capable of providing real-time data regarding the patient's physiology, the position 
and movement of the urethra, and the muscular strength of the patient's vagina and pelvic 
floor. The methods and devices of the invention may also be useful to addressing other 
medical issues, including urinary incontinence, sexual health, and fecal incontinence, as well 
as facilitate patient home wellness activities.
Patent AU-2019206306-B2 (AU)
Title: System and methods
Inventor: FRYERS ROBERT JOHN CLAYTON
IPC: A01M1/02
Filed: 2019-01-11
Granted: 2024-01-18
Abstract: A system for detecting the presence of pests, the system comprising: at least one remote camera system, each of the at least one remote camera system comprising an image capture device coupled to a processor and a wireless transmitter, each of the at least one remote camera system having a pest detection surface and being configured to: capture one or more image of the pest detection surface; process the captured one or more image to recognise the potential presence of a target pest on the pest detection surface; and transmit data from the captured one or more image in response to recognising the potential presence of one or more target pests; and a server configured to: receive the transmitted data; process the transmitted data to verify the potential presence of the target pest on the pest detection surface; and provide an output indicating the verification.
Patent AU-2019214077-B2 (AU)
Title: Method for dividing ecological and geological environment types based on coal resource development
Inventor: LI WENPING
IPC: G06Q50/02
Filed: 2019-01-25
Granted: 2021-10-14
Abstract: A method for dividing ecological and geological environment types based on coal resource development, relating to the field of ecological and geological environmental protection, and used for solving the problem that the prior art lacks consideration of the combination of the different geological environments and ecological environments of the earth surface in mining areas before implementing coal mining activities. On the basis of investigation into materials related to the ecology, hydrology, and geology of an area, the present invention combines a fuzzy Delphi hierarchy analysis method with a weighted fuzzy C-means clustering method to determine different ecological and geological environment types. On the basis of existing ecological, hydrological, and geological materials, the present invention can quickly and effectively divide different ecological and geological environment types, and determine ecological and geological features and the sensitivity thereof to coal resource exploitation, in order to protect cherished phreatic resources in arid and semi-arid areas, and provide a scientific basis for the selection of suitable coal mining methods for the development and utilisation of coal mining resources whilst maintaining fragile ecological environments, and therefore being of great significance for water conservation and coal mining in the fragile ecological environments of the north-west of China.
Patent AU-2019214536-B2 (AU)
Title: Eyewear and lenses with multiple molded lens components
Inventor: MARCO COPPA
IPC: B29D11/00
Filed: 2019-02-01
Granted: 2021-11-11
Abstract: Certain embodiments disclosed herein include lenses for eyewear with a molded wafer and a molded clear resin lens component integrated onto a surface of the molded wafer. The molded wafer can include an optical filter that enhances one or more properties of filtered light. The optical filter can be, for example, a contrast-enhancing, color-enhancing, and/or chroma-enhancing filter. The clear resin lens component can be shaped such that the lenses have optical power. In some embodiments, the molded wafer is integrated onto a surface of a polarizing wafer.
Patent AU-2019246821-B2 (AU)
Title: Anti-cd40 antibodies and uses thereof
Inventor: REIMANN KEITH A
IPC: C07K16/28
Filed: 2019-10-09
Granted: 2021-01-14
Abstract: The present invention relates to antibodies specific for a particular epitope on CD40 and 
antibodies that bind CD40 and have particular functional characteristics. The present 
invention also relates to fragments of these antibodies, uses of the antibodies for reduction 
or treatment of transplant rejection and graft-versus-host disease, and methods for making 
the antibodies.
Patent AU-2019262144-B2 (AU)
Title: RIP1 inhibitory compounds and methods for making and using the same
Inventor: MASUDA ESTEBAN
IPC: C07D413/14
Filed: 2019-05-02
Granted: 2023-11-16
Abstract: Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceutical compositions, and/or combinations may be used to treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition.
Patent AU-2019279932-B2 (AU)
Title: Portable and modular transportation unit with improved transport capabilities
Inventor: KAUSHANSKY YEFIM
IPC: A61M60/495
Filed: 2019-12-09
Granted: 2021-10-07
Abstract: A medical device, such as an intra-aortic balloon pump or carrier with an extendable wheel track and 
handle configured to be removably carried and integrated with a cart. The wheel track is configured to 
extend upon extension of the handle and to return to its original position upon retraction of the handle.
Patent AU-2019284469-B2 (AU)
Title: Sphincterotomes and methods for using sphincterotomes
Inventor: WEITZNER BARRY
IPC: A61B18/00
Filed: 2019-06-10
Granted: 2021-11-25
Abstract: Sphincterotomes and methods for making and using sphincterotomes are disclosed. An example sphincterotome may include an elongate shaft having an outer surface and a distal end region. The sphincterotome may also include a sphincterotome wire assembly having a distal end coupled to the distal end region of the elongate shaft and a body portion extending along the outer surface of the elongate shaft. The sphincterotome wire assembly may be designed to shift the distal end region of the elongate shaft between a first configuration and a curved configuration. The body portion of the sphincterotome wire assembly may include a cutting region and a non-conductive region.
Patent AU-2019301947-B2 (AU)
Title: 3-(5-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and their use in the treatment of I KAROS Family Zinc Finger 2 (IKZF2)-dependent diseases
Inventor: BECKWITH ROHAN ERIC JOHN
IPC: C07D401/14
Filed: 2019-07-08
Granted: 2021-07-22
Abstract: The present disclosure provides a compound of Formula (I'): (I') or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein R
Patent AU-2019388208-B2 (AU)
Title: Mould powder and mould coating
Inventor: GUILLEMIN FRANÇOIS
IPC: B22C3/00
Filed: 2019-11-28
Granted: 2022-11-17
Abstract: The present invention relates to a mould powder for coating cast moulds for reducing surface defects, such as pinholes, in ductile cast iron products. The mould powder comprises10 –99.5% by weight of a ferrosilicon alloy, 0.5-50% by weight of iron sulphide,and optionally1-30% by weight of CaSi, and/or 1-10% by weight of CaF
Patent AU-2020202112-B2 (AU)
Title: Nucleoside phosphoroamidate esters and derivatives thereof, use and synthesis thereof
Inventor: KOKORIS MARK STAMATIOS
IPC: C07H19/14
Filed: 2020-03-25
Granted: 2021-08-12
Abstract: Interwovn\NRPortbl\DCC\AAR\20017172_l.docx-25/03/2020 
ABSTRACT 
Phosphoramidate esters and related nucleotide analogs useful in polynucleotide sequencing 
techniques, and synthetic methods for preparing those compounds, are disclosed. These 
compounds include nucleotide phosphoramidates analogs that are modified on the alpha
phosphate to enable attachment of a variety of application-specific substituents such as tether 
molecules.
Patent AU-2020230291-B2 (AU)
Title: Source color volume information messaging
Inventor: CHEN TAO
IPC: H04N19/186
Filed: 2020-09-10
Granted: 2022-09-01
Abstract: Methods in a decoder to extract source color volume information of an input bitstream from 
an SEI message are described. A method executed on a processor comprises: receiving an 
SEI message comprising one or more source color SEI parameters, the one or more source 
color SEI parameters comprising color primary component parameters and luminance value 
parameters; for a color primary component c, extracting x and y chromaticity coordinates 
from the color primary component parameters, wherein the x and y chromaticity coordinates 
define, respectively, normalized x and y chromaticity coordinates of the color primary 
component c of the input bitstream; and extracting one or more of a minimum, a maximum, 
and an average luminance value from the luminance value parameters, wherein the minimum, 
the maximum, and the average luminance values are for an active region of one or more 
decoded pictures in the input bitstream.
Patent AU-2020256502-B2 (AU)
Title: Cryopreservation solution without DMSO, preparation method therefor and application thereof
Inventor: YAN JIE
IPC: A01N1/02
Filed: 2020-03-02
Granted: 2023-08-17
Abstract: Disclosed by the present invention is a cryopreservation liquid without DMSO. On the basis of a volume of every 100 mL, the cryopreservation solution contains 0.01-50.0 g of bionic ice control materials, 5.0-30 mL of polyols, 1-30 g of water-soluble sugar, and 0-30 mL of serum, the rest being a buffer solution. The bionic ice control materials are selected from PVA and/or amino acid bionic ice control materials. The cryopreservation solution according to the present invention and a freezing balancing solution do not contain DMSO. When being used for the cryopreservation of mouse oocytes and embryos, the described solution may achieve the same or an even higher cell and tissue survival rate and functional expression stability as or than a commercial cryopreservation solution (containing 15% DMSO), and has high preservation efficiency. The cryopreservation solution without DMSO or serum further solves the problems wherein parasitic biological contaminants may be introduced and stability is poor due to the commercial cryopreservation solution currently commonly used in clinical practice containing serum. The cryopreservation solution according to the present invention has a simple composition, a convenient source of raw materials and is low-cost, and may be widely applied in the cryopreservation of various types of cells.
Patent AU-2020294177-B2 (AU)
Title: Automatic print bleed correction systems and methods
Inventor: SEETO MICHELLE MUNN WAI
IPC: G06F3/12
Filed: 2020-12-22
Granted: 2024-02-01
Abstract: Described herein is a computer implemented method. The method comprises selecting a 
plurality of elements on a design page and, for each selected element, determining a 
plurality of edge bleed pairs, each edge bleed pair including a particular edge and a 
particular bleed of the design page. Each edge bleed pair is processed to determine 
whether the selected element should be resized, the determination being based on the 
position of the particular edge relative to the particular bleed. If the determination is that 
the element should be resized, the method involves resizing the selected element so that 
the element covers a greater portion of the particular bleed than was originally covered 
by the element.
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158 
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Patent AU-2020306672-B2 (AU)
Title: Mammalian cell lines with SIRT-1 gene knockout
Inventor: AUSLAENDER SIMON
IPC: C12N15/85
Filed: 2020-06-24
Granted: 2023-08-24
Abstract: Herein is reported a method for generating a recombinant mammalian cell expressing a heterologous polypeptide and a method for producing a heterologous polypeptide using said recombinant mammalian cell, wherein in the recombinant cell the expression of the endogenous SIRT-1 gene has been reduced. It has been found that the knockout of the sirtuin-1 gene (SIRT-1) in mammalian cells, e.g. such as CHO cells, improves recombinant productivity and reduces lactate production by the cells. Additionally, it has been found that the viability decline at the end of a fed-batch fermentation is reduced.
Patent AU-2021204268-B2 (AU)
Title: Seating arrangement
Inventor: LUDWIG JAMES NOLAN
IPC: A47C3/025
Filed: 2021-06-23
Granted: 2023-02-02
Abstract: OF THE DISCLOSURE 
A seating arrangement includes an upwardly-extending back arrangement 
movable between an upright and reclined positions, and a seat arrangement that 
includes a first link member extending horizontally and having forward and rearward 
portions, a second link member spaced from the first link member, a third link member 
coupled to the first and second link members and substantially flexible along a majority 
of a length thereof, and a fourth link member operably coupled to the first and second 
link members, the fourth link member being substantially rigid along a majority of a 
length thereof, wherein the link members cooperate to form a linkage arrangement, and 
wherein the seat arrangement moves in a rearward direction as the back arrangement is 
moved between the upright position and the reclined position.
Patent AU-2021213039-B2 (AU)
Title: Jump starting device with enhanced (Turbo) boost mode
Inventor: NOOK JONATHAN LEWIS
IPC: H02J7/04
Filed: 2021-01-04
Granted: 2023-04-27
Abstract: Provided is a jump starting device for boosting a depleted or discharged battery having a positive terminal and negative terminal, including a battery device including multiple battery cells connected together in series, a positive battery connector for connecting the positive terminal of the battery device to the positive terminal of the depleted or discharge battery, a negative battery connector for connecting the negative terminal of the battery device battery to the negative terminal of the depleted or discharged battery, and electronics in circuit with the battery device, positive battery connector, and negative battery connector, the electronic configured for selectively connecting at least one or more battery cells of the battery device to the depleted or discharge battery in a normal boost mode or in an enhanced boost mode.
Patent AU-2021241470-B2 (AU)
Title: Combination therapy with a mutant IDH inhibitor and a Bcl-2 inhibitor
Inventor: BROOKS NATHAN ARTHUR
IPC: A61K31/5395
Filed: 2021-03-22
Granted: 2023-12-14
Abstract: The present invention relates to combination therapy with a mutant IDH inhibitor of Formula (I) and a Bcl-2 inhibitor, for the treatment of cancer.
Patent AU-2021282515-B2 (AU)
Title: Stabilizing features in a wear member assembly
Inventor: BILAL MOHAMAD
IPC: E02F9/28
Filed: 2021-12-09
Granted: 2024-02-01
Abstract: A wear member assembly may include a nose attachable to a bucket lip. The 
nose may include a rear portion having a first set of substantially planar surfaces 
including a first, second, and third subset of surfaces. The third subset of surfaces 
may be angled and positioned between the first subset of surfaces and the second 
subset of surfaces. The nose may also include a forward portion positioned forwardly 
adjacent to the rear portion, the forward portion having a second set of substantially 
planar surfaces including a fourth, fifth, and sixth subset of surfaces. The sixth set of 
surfaces may be angled and positioned between the first subset of surfaces and the 
second subset of surfaces. The wear member assembly may also include a wear 
member having a cavity comprising rear and forward bearing surfaces corresponding 
to the third and sixth subset of surfaces.
Patent AU-2021354279-B2 (AU)
Title: Cylindrical battery cell, battery, electric device, manufacturing method, and manufacturing system
Inventor: WU KAI
IPC: H01M50/533
Filed: 2021-08-18
Granted: 2023-10-12
Abstract: Embodiments of the present application relate to a cylindrical battery cell, a battery, an electric device, a manufacturing method, and a manufacturing system. The cylindrical battery cell comprises: a housing having openings; and electrode assemblies provided in the housing. Each electrode assembly comprises a diaphragm and a tab; in the axial direction of the electrode assembly, the tab is located at one end of the electrode assembly and extends towards the opening; the tab comprises a first portion and a second portion; the second portion surrounds the periphery of the first portion; the diaphragm wraps the second portion to isolate the second portion from the housing, wherein in the axial direction, the first portion exceeds the second portion and the diaphragm, and the second portion does not exceed the diaphragm. The battery cell of the present application aims at solving the technical problem of short circuit of the battery cell.
Patent AU-2022215189-B2 (AU)
Title: New forms of pyrido[1,2-a]pyrimidin-4-one derivatives, its formulation and its process of making
Inventor: MEIER ROLAND
IPC: C07D519/00
Filed: 2022-08-09
Granted: 2023-11-09
Abstract: The present invention relates to a process for preparation of 7-(4,7-diazaspiro[2,5]octan-7-yl)-2-(2,8
dimethylimidazo[1,2-b]pyridazine-6-yl)pyrido[1,2-a]pyrimidin-4-one useful as pharmaceutically 
active compounds