baber/WOPTO huggingface dataset:
Patent AU-2018240559-A1 (AU)
Title: Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing
Inventor: KENNEDY SCOTT R
IPC: C12Q1/68
Filed: 2018-03-23
Abstract: The present technology relates generally to methods and compositions for targeted nucleic acid sequence enrichment, as well as uses of such enrichment for error-corrected nucleic acid sequencing applications. In some embodiments, highly accurate, error corrected and massively parallel sequencing of nucleic acid material is possible using a combination of uniquely labeled strands in a double-stranded nucleic acid complex in such a way that each strand can be informatically related to its complementary strand, but also distinguished from it following sequencing of each strand or an amplified product derived therefrom. In various embodiments, this information can be used for the purpose of error correction of the determined sequence.
Patent AU-2018247255-A1 (AU)
Title: Single chain fc fusion proteins
Inventor: MOUSTAKAS DEMETRI T
IPC: C07K16/30
Filed: 2018-10-10
Abstract: The present invention provides novel, single chain Fc fusion proteins having improved properties. The invention provides single chain fusions of soluble proteins fused to the Fc region of an immunoglobulin via a novel linker comprising a constant region of an immunoglobulin light chain linked to a CH 1 constant region of an immunoglobulin heavy chain. This novel linker confers favorable properties on the Fc fusion proteins of the invention such as improved bioactivity and increased half-life as compared to non-Fc fusion counterparts or as compared to prior art Fc fusion proteins. The novel Fc fusion protein scaffold as described herein may be designed to include soluble proteins of interest capable of binding or interacting with any target of interest. Preferably, the Fc fusion protein of the invention is a dimer. The dimer preferably forms via a disulfide bond between free cysteine residues in the hinge region of two monomeric Fc fusion proteins of the invention.
Patent AU-2018249920-A1 (AU)
Title: Method and system for nuclear waste storage and monitoring
Inventor: DOWNEY MARLAN
IPC: G01L19/08
Filed: 2018-03-01
Abstract: A method comprising storing nuclear waste, including identifying a subterranean storage site location having a shale rock layer. The layer has an expected fluid overpressure in a range corresponding to greater than hydrostatic pressure to less than lithostatic pressure from overlying rock layers. Storing the waste can include forming a storage borehole, with an end segment of the storage borehole located within the layer and measuring the fluid pressure in the end segment of the storage borehole. If the measured fluid pressure in the end segment of the storage borehole is in the expected fluid overpressure range, forming a monitoring borehole in the layer with an end segment of each of the monitoring boreholes being in a vicinity of the end segment of the storage borehole and storing nuclear waste in the end segment of the storage borehole. A system for storing and monitoring nuclear waste is also described.
Patent AU-2018250469-A1 (AU)
Title: A mobile adjustable stairway and method of use thereof
Inventor: NIELSEN KODEY CHARLES
IPC: E04F11/04
Filed: 2018-10-18
Abstract: (Figure 2) The present invention relates to a mobile adjustable stairway for use in gaining access to large machinery, equipment, vehicles and the like. The mobile adjustable stairway includes a base frame configured to convey the stairway along a surface; a first frame slidably mounted to the base frame and having a first flight of stairs; and a second frame slidably mounted to the base frame and having a second flight of stairs. The first and second frames are each slidably moveable relative to the base frame between a retracted position and an extended position to adjust a height of the stairway and to align the first flight of stairs and the second flight of stairs relative to one another. 120Fiue Figure 2
Patent AU-2018323955-A1 (AU)
Title: Anti-LAG-3 antibodies and uses thereof
Inventor: WANG MINGHAN
IPC: A61K39/00
Filed: 2018-08-28
Abstract: Anti-LAG-3 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancer, an inflammatory disease, an autoimmune disease, type 1 diabetes, and/or infectious diseases.
Patent AU-2018356947-A1 (AU)
Title: A filter for a smoking article or an aerosol generating product
Inventor: MIAH REZAUL
IPC: A24D3/06
Filed: 2018-10-23
Abstract: A filter for a smoking article or an aerosol generating product comprising a first filter section and a second filter section, the second filter section being located downstream of the first filter section; the first filter section comprising filter material and two or more capsules comprising additive, the capsules being disposed in an axial region proximal a longitudinal axis of the filter and being spaced in sequence in a direction along the axis; the second filter section comprising at least one channel located in an axial region of the second filter section proximal a longitudinal axis of the filter, to facilitate, in use, drawing of an aerosol through the axial region of the first filter section in which the capsules are disposed.
Patent AU-2018402162-A1 (AU)
Title: User terminal and radio communication method
Inventor: TAKEDA KAZUKI
IPC: H04W72/12
Filed: 2018-01-11
Abstract: The present invention improves throughput of wireless communication using a partial bandwidth in downlink (DL)/uplink (UL) communication. This user terminal has: a reception unit which receives downlink control information using, among bandwidth parts (BWPs) set within a carrier, a first BWP; and a control unit which identifies a resource for a second BWP different from the first BWP in the downlink control information via a resource allocation field (RA field) having a size set on the basis of a predetermined BWP among the multiple BWPs.
Patent AU-2019201488-A1 (AU)
Title: Cas9 variants and uses thereof
Inventor: LIU DAVID R
IPC: C07K14/315
Filed: 2019-03-05
Abstract: Some aspects of this disclosure provide compositions, methods, and kits for improving the specificity of RNA-programmable endonucleases, such as Cas9. Also provided are variants of Cas9, e.g., Cas9 dimers and fusion proteins, engineered to have improved specificity for cleaving nucleic acid targets. Also provided are compositions, methods, and kits for site specific nucleic acid modification using Cas9 fusion proteins (e.g., nuclease-inactivated Cas9 fused to a nuclease catalytic domain or a recombinase catalytic domain). Such Cas9 variants are useful in clinical and research settings involving site- specific modification of DNA, for example, genomic modifications.
Patent AU-2019204464-A1 (AU)
Title: Headgear
Inventor: BROWN KYLE GREGORY
IPC: A62B9/00
Filed: 2019-06-25
Abstract: Headgear for a respiratory interface comprising multiple separate sections of material joined to form the headgear and different levels of resilient extensibility or stretchability in at least four different parts or straps of the headgear.
Patent AU-2019210536-A1 (AU)
Title: Improved plumbing fitting and attachment
Inventor: BOLTON LUKE
IPC: E03C1/02
Filed: 2019-07-30
Abstract: The invention relates to an improved attachment means for a plumbing fitting, for 
attaching an inlet to a form, the attachment means including: a face having connecting 
means for connecting to an inlet, a base opposite the face and walls between the face 
and the base, wherein the walls define a depth between the face and base sufficient to 
accommodate a channel for receiving a fixing element; and a channel located between 
the face and base of the attachment means, said channel passing from one wall to 
another wall of the attachment means, configured to receive a fixing element to attach 
the plumbing fitting to a form. The invention also relates to a plumbing fitting comprising 
the improved attachment means.
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Fig.21
Patent AU-2019211028-A1 (AU)
Title: Medical tubes for breathing circuit
Inventor: BUSWELL MATTHEW LIAM
IPC: A61M16/08
Filed: 2019-01-24
Abstract: A breathing circuit for use in respiratory therapy includes an inspiratory tube and an expiratory tube. The inspiratory tube of the breathing circuit has a smooth bore. The expiratory tube of the breathing circuit is corrugated. Preferably, the expiratory tube is vapor permeable. Using the combination of a smooth bore inspiratory tube with a corrugated expiratory tube has the unexpected result of improving the performance of the breathing circuit and its components.
Patent AU-2019222929-A1 (AU)
Title: Prosthetic heart valve
Inventor: LEVI TAMIR
IPC: A61M29/02
Filed: 2019-08-30
Abstract: PROSTHETIC HEART VALVE A balloon-expandable prosthetic aortic heart valve (10) with a radially collapsed state and radially expanded state, the prosthetic aortic heart valve (10) comprising: a balloon expandable frame (12) comprising a material selected from a group comprising stainless steel and a cobalt-chromium alloy, the frame comprising: an inflow row of openings (36) at an inflow end portion of the frame (12); an outflow row of openings (40) at an outflow end portion of the frame (12); and at least one intermediate row of openings (38) between the inflow row of openings (36) and outflow row of openings (40); wherein the inflow row of openings (36) is formed by a circumferentially extending lower row of angled struts arranged end-to-end and a circumferentially extending first intermediate row of angled struts arranged end-to-end, the lower and first intermediate rows of angled struts interconnected by a plurality of substantially straight, axially extending struts; and wherein the outflow row of openings (40) is formed by a circumferentially extending upper row of angled struts arranged end-to-end and a circumferentially extending second intermediate row of angled struts arranged end-to-end, the upper and second intermediate rows of angled struts interconnected by a plurality of axially extending struts and a plurality of angularly spaced, axially extending commissure window frame portions, wherein each axially extending strut and each commissure window frame portion of the outflow row of openings (40) extends from a location defined by the convergence of the lower ends of two angled struts of the upper row of angled struts to another location defined by the convergence of the upper ends of two angled struts of the second intermediate row of angled struts.
Patent AU-2019230458-A1 (AU)
Title: A high sensitivity and selectivity real-time spectrum analyser
Inventor: SNITKOVSKY VYACHESLAV
IPC: G01R23/16
Filed: 2019-03-07
Abstract: There is provided herein a spectrum analyser and a method of operation thereof which is able to receive and analyse interference signals in a way that is substantially immune to sporadic interferences, allowing for more accurate detection of the interferences of the surrounding electromagnetic environment and therefore the more accurate setting of communication equipment operational parameters accordingly including receiving frequency and selectivity. In embodiments, the present spectrum analyser is able to detect three or more sources of powerful interference.
Patent AU-2019232852-A1 (AU)
Title: Rock drilling machine, rig and method for reinforcing rock surfaces
Inventor: MÄNTTÄRI MAUNU
IPC: E21B7/00
Filed: 2019-09-19
Abstract: Abstract A rock drilling machine, rock drilling rig and method of reinforcing rock surfaces by means of grouting material. The grouting ma terial (13) is fed through the rock drilling machine (6) to a drilling tool (7) connected to the rock drilling machine. The rock drill ing machine comprises a flushing feed path, which is utilized in the feeding of the grouting material. (Figure 3) Reinforcing rock surface Drilling drill holes Injecting grouting material through drilling machine and tool Feeding via basic flushing system or part of it Inserting rock bolt or leaving self-drilling rock bolt inside drill hole Tightening inserted rock bolt after grouting material is hardened Flushing grouting feed means and basic flushing system
Patent AU-2019256523-A1 (AU)
Title: Curative
Inventor: AMSTUTZ AARON KENNETH
IPC: B32B25/10
Filed: 2019-04-18
Abstract: A curative for epoxidized plant-based oils and epoxidized natural rubber is created from the reaction between a naturally occurring polyfunctional acid and an epoxidized plant-based oil is disclosed. The curative may be used to produce porosity-free castable resins and vulcanize rubber formulations based on epoxidized natural rubber. Materials made from disclosed materials may be advantageously used as leather substitutes.
Patent AU-2019265111-A1 (AU)
Title: Method for performing single-cell analysis and device therefor
Inventor: HOSOKAWA MASAHITO
IPC: C12N15/10
Filed: 2019-04-26
Abstract: The present invention provides a genome library production method in which cell lysis and genome amplification are performed using a simple operation. More particularly, the present invention provides a method that is for amplifying polynucleotides in cells and that comprises: a step for using a sample containing two or more cells or cell-like structures, and encapsulating the cells or cell-like structures into droplets, one for each droplet; a step for gelling the droplets to generate gel capsules; a step for performing lysis of the cells or cell-like structures by immersing the gel capsules in one or more types of reagents for lysis so as to cause the polynucleotides in the cells to be eluted in the gel capsules and to be kept in the gel capsules in a state where substances binding to the polynucleotides are removed; and a step for bringing the polynucleotides into contact with a reagent for amplification to amplify the polynucleotides in the gel capsules.
Patent AU-2019282735-A1 (AU)
Title: Beverage ingredient pod
Inventor: ANDERSON KEYONNA
IPC: B65D51/00
Filed: 2019-06-06
Abstract: A beverage ingredient pod for releasing beverage ingredients into a bottle to create a mixed beverage includes a liquid-ingredient chamber, a solid-ingredient chamber, a frangible membrane between and separating the liquid-ingredient chamber and the solid-ingredient chamber, and a rigid piercer that extends to a point toward the frangible membrane. Upon a force applied to the beverage ingredient pod, a portion of the pod collapses and drives the rigid piercer through the frangible membrane. This mixes contents of the liquid-ingredient chamber with contents of the solid-ingredient chamber and releases the mixed contents from the beverage ingredient pod into a bottle below that is filled with a liquid, creating a mixed beverage.
Patent AU-2019293409-A1 (AU)
Title: Abnormality sensing device and abnormality sensing method
Inventor: IZUMI MASAMI
IPC: G06F21/55
Filed: 2019-06-24
Abstract: An abnormality sensing device (30) is provided with: a learning unit (31) that uses a communication log during normal operation of a communication apparatus (10) as learning data to generate a sensing model; and an abnormality sensing unit (32) that uses the generated sensing model to sense an abnormality of the communication apparatus (10). The abnormality sensing device (30) is provided with: a data acquisition unit (330) that acquires a communication log (second communication log) which occurred a predetermined length of time later than a first communication log; and a determination unit (334) that, if there is differential information between the learning data (first communication log) of the current sensing model and the second communication log, commands re-learning using the second communication log, when a number of additional pieces of information (information on additional flow) or number of deleted pieces of information (information on deleted flow) included in the differential information meets a predetermined assessment criterion.
Patent AU-2019300838-A1 (AU)
Title: Engineered pantothenate kinase variant enzymes
Inventor: BORRA-GARSKE MARGIE TABUGA
IPC: C12N9/88
Filed: 2019-07-02
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
Patent AU-2019311583-A1 (AU)
Title: Data warehousing system and process
Inventor: SEARLE RUSSELL
IPC: G06F16/00
Filed: 2019-07-25
Abstract: A data warehouse system including a plurality of input event queues that receive a plurality of data messages with message types, including one of the input event queues for each message type; a plurality of input transform operators that transform payload data in the data messages into raw data records, including one of the input transform operators and at least one of the raw data records for each message type; a raw data storage system that stores the raw data messages; a plurality of output transform operators that transform the raw data records into business or operational data records based on output rules defining output requirements; and a business data storage system that stores the business data records for generating outputs associated with the output requirements.
Patent AU-2019341638-A1 (AU)
Title: Signal processing
Inventor: MARIANI STEFANO
IPC: G01N29/36
Filed: 2019-06-19
Abstract: A method of processing a signal is disclosed. The method comprises receiving a signal obtained from measuring a structure under a given set of environmental and/or operational conditions, the signal comprising a set of amplitude values which depend on position in the signal and adjusting the amplitude value each of at least two of the amplitude values independently according to the position of the amplitude value in the signal and according to the given environmental and/or operational conditions.
Patent AU-2019351406-A1 (AU)
Title: Method for generating screenshot, control method, and electronic device
Inventor: Zhou Shanru
IPC: H04M1/72469
Filed: 2019-09-25
Abstract: Embodiments of the present application relate to the field of electronic devices. Disclosed are a method for generating a screenshot, a control method, and an electronic device, for use in solving the problem of poor intelligence of human-machine interaction due to a limited amount of information included in the screenshot. The solution is applied to an electronic device comprising a display screen and a camera. The display screen is provided with a through hole, and the camera is embedded inside the through hole; the electronic device displays, on the display screen, a primary screen comprising the icon of a first application; receiving an operation on the icon of the first application by a user; in response to the operation, displaying, on the display screen, the interface of the first application; receiving a screenshot operation by the user; in response to the screenshot operation, drawing the screenshot of the interface of the first application, and automatically adding the icon corresponding to the first application to the position in the screenshot of the interface of the first application corresponding to the through hole; and displaying a screenshot including the icon corresponding to the first application.
Patent AU-2019379604-A1 (AU)
Title: Als treatment using induced regulatory T (iTREG) cells
Inventor: FOWLER DANIEL HARDING
IPC: A61K35/17
Filed: 2019-11-15
Abstract: The present disclosure provides methods for treating ALS using pentostatin and cyclophosphamide treatment followed by TREG and/or TREG/Th2 hybrid cells from dedifferentiated T cells. The present disclosure further provides methods for producing TREG and TREG/Th2 hybrid cells from de-differentiated T cells, said TREG and TREG/Th2 hybrid cells, populations thereof and compositions thereof. Methods for producing de-differentiated T cells, said de-differentiated T cells, populations thereof and compositions thereof are also provided.
Patent AU-2019394564-A1 (AU)
Title: A drilling string, threaded coupling, and rod adaptor for rotary drilling
Inventor: SURYADEVARA MANOJ KUMAR
IPC: E21B17/042
Filed: 2019-11-06
Abstract: A drill string (400) for rotary drilling of underground mining machines including a first elongate drill string member (100) and a second elongate drill string member (100). The first member has a main section (101) and a male end (102), the second member has a main section (101) and a female end (103). The male (102) and female (103) ends have respective threads to provide a thread coupling (401) between the male (102) and female (103) ends, the thread coupling enables the male end (102) to be secured inside the female end (103) such that the male and female ends overlap axially, wherein a thread lead (L2) of the respective threads of the male and the female ends is greater than a diameter (DM, DFI) of the male end (102) and the female end (103).
Patent AU-2019396352-A1 (AU)
Title: System and process for conducting in-field operations
Inventor: CLARKE RODNEY K
IPC: E02F9/00
Filed: 2019-12-09
Abstract: A handling apparatus for conducting in-field operations such as removing and/or installing wear parts on earth working equipment along a controlled path. The apparatus can include a crane, a joint having three axes of articulation and a tool.
Patent AU-2019397033-A1 (AU)
Title: Chimeric antigen receptors and CAR-T cells and methods of use
Inventor: BELK JONATHAN
IPC: A61K39/00
Filed: 2019-12-11
Abstract: Provided is a chimeric antigen receptor (CAR) or a T cell receptor (TCR) comprising one or more of the antigen binding motifs disclosed herein. Aspects of the disclosure relate to a polynucleotide encoding a chimeric antigen receptor (CAR) or a T cell receptor (TCR) comprising one or more of the antigen binding motifs. Provided are antibodies and antigen binding systems that comprise a binding motif that binds CD20 and optionally a binding motif that binds CD 19, and methods of producing and using the same. Antibodies and antigen binding systems of the present disclosure comprise CARs that comprise an anti-CD20 binding motif and an anti-CD 19 binding motif. Provided are compositions, such as antibodies and CARs that are or comprise an anti-CD20/anti-CDl9 antigen binding system of the present disclosure, and cell therapies comprising the same, are useful, e.g., in the treatment of cancer.
Patent WO-2020220086-A1 (WO)
Inventor: SCOBLE JUDITH
IPC: G01N21/76
Filed: 2020-04-30
Abstract: The present invention relates to methods for detecting analytes in a sample. The methods may also be used to determine the amount of analyte in the sample. The present invention also relates to antibody or antibody-like molecules and labelled antigens for use in these methods.