baber/WOPTO huggingface dataset:
Patent AU-2020276702-A1 (AU)
Title: Catheter assembly
Inventor: FOMINAS ALEKSEJUS
IPC: A61M25/00
Filed: 2020-05-15
Abstract: A catheter assembly (10) may include a catheter member (200) having a proximal portion and an outer surface; an introducer (100, 300) having a lumen configured to receive the proximal portion of the catheter member; and a sleeve (160) having a compressed portion (168) housed in the lumen of the introducer, the sleeve being configured to evert over the outer surface as the catheter member is inserted through the lumen of the introducer. The proximal portion of the catheter member may be configured to push a distal portion (164) of the sleeve proximally, and the compressed portion of the sleeve may form a soft proximal tip of the catheter assembly as the catheter member exits a proximal opening of the introducer.
Patent AU-2020286189-A1 (AU)
Title: A table having a heating appliance
Inventor: RITCHIE GUY STUART
IPC: F24C15/30
Filed: 2020-12-08
Abstract: A table (1) has a tabletop (2) containing an opening (3). A heating 
appliance (10) is in the opening (3) wherein the heating appliance (10) 
extends at least beneath the tabletop (2). The tabletop opening (3) 
comprises a recess (5) in which the heating appliance (10) is received, and 
the recess (5) has at least one wall (7) below the tabletop (2). The heating 
appliance (10) has a substantially sealed chamber (13) for receiving 
combustible fuel (47) with which the heating appliance (10) is used, and the 
chamber (13) has at least one window (35, 45).  
(Fig.3)
WO 2019/043351 PCT/GB2018/000117 
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Patent AU-2020315279-A1 (AU)
Title: Device, system, and method for changing angle of incidence of a filter or filter wheel
Inventor: STEWART DAVID
IPC: G01N21/78
Filed: 2020-07-10
Abstract: This disclosure is directed to a system and method for changing an angle of incidence of a filter or filter wheel.
Patent AU-2020332268-A1 (AU)
Title: Novel peptide, compositions and method for delivery of agents into cells and tissues
Inventor: KUMAR-SINGH RAJENDRA
IPC: C07K7/08
Filed: 2020-07-02
Abstract: Cell penetrating peptides that target many cells types including cells of the retina and cornea with high efficiency are provided herein. These peptides can be used to deliver cargo molecules across a plasma membrane, without the need for chemical conjugation. Compositions and viral vectors comprising these cell-penetrating peptides are also provided. Methods of using the peptides, compositions and viruses to deliver various agents to target cells and tissues are also provided.
Patent AU-2020344154-A1 (AU)
Title: Treatment of RMS by switching therapy
Inventor: RAMANATHAN KRISHNAN
IPC: C07K16/28
Filed: 2020-09-10
Abstract: The present invention relates to the anti-CD20 monoclonal antibody ofatumumab for use in the treatment or prevention of relapsing multiple sclerosis, wherein ofatumumab is used in a patient who has been treated with a disease-modifying therapy other than ofatumumab.
Patent AU-2020367043-A1 (AU)
Title: Joint sensing
Inventor: REDDALL NICHOLAS HENRY
IPC: A61B5/107
Filed: 2020-10-15
Abstract: A method of calibrating a pair of body mounted sensors, the method comprising the steps of: (a) in a baseline position of a joint to be measured, determining a first offset between a measured joint angle and an angle between pair of sensors, one mounted on each side of the joint to be measured, so as to calibrate the sensors; (b) after at least one of the sensors has been removed and reapplied, placing the joint back into the baseline position such that the sensors are in a second configuration relative to each other; and (c) determining a second offset between the measured knee angle and an angle between the pair of sensors in the second configuration in order to recalibrate the sensors such that, in each of the first and second configurations, the same joint angle for the baseline position is reported.
Patent AU-2020368599-A1 (AU)
Title: Pressing tool and method for producing a pressing tool
Inventor: HAGEDORN THORSTEN
IPC: B30B3/00
Filed: 2020-10-12
Abstract: The invention relates to a method for producing a pressing tool (1, 51) provided for manufacturing a workpiece, which pressing tool has a pressing surface (2) having a structure consisting of elevations (4) and depressions (3). A mask (24) is applied in order to cover regions and then a metal layer (22) is applied to the regions (25) not covered by the mask (24) with the addition of mineral particles (23). This is repeated until the pressing surface (2) having the structure consisting of elevations (4) and depressions (3) is created by repeated, layer-by-layer application of masks (24) and metal layers (22) with the addition of mineral particles (23).
Patent AU-2020374893-A1 (AU)
Title: Methods and devices using cartridges for sequencing
Inventor: ROTHBERG JONATHAN M
IPC: C12N15/10
Filed: 2020-10-28
Abstract: Methods and devices for enriching and analyzing target molecules from a sample are provided herein. In some embodiments, methods and devices using cartridges involve enrichment of target molecules (e.g., using SCODA) and detection and analysis using sequencing. The method may employ lysing of cells, fragmentation of target in the sample preparation module and enriching the target in the module and moving the target to the sequencing module.
Patent AU-2020401357-A1 (AU)
Title: Interleukin 2 chimeric constructs
Inventor: KLATZMANN DAVID
IPC: C07K14/55
Filed: 2020-12-11
Abstract: The present invention relates to a chimeric construct, comprising i) an interleukin 2 (IL2) moiety and ii) a beta chain of the C4b-binding protein (C4BPβ) or at least one fragment or functional variant thereof that is capable of forming a dimeric protein.
Patent AU-2020404817-A1 (AU)
Title: Bispecific antibodies with alternatively matched interchain cysteines and uses thereof
Inventor: LI JACK CHONGYANG
IPC: C07K16/18
Filed: 2020-12-03
Abstract: Engineered bispecific antibodies with shifted interchain disulfide bond on one arm while maintaining the native interchain disulfide bond on the second arm are described. Also described are anti-CD47/FRα bispecific antibodies and antigen-binding fragments thereof. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases, such as cancer and/or associated complications.
Patent AU-2020414244-A1 (AU)
Title: Polypeptides comprising mutated forms of human vegf-a with rearrangements of disulfide bonds and compositions containing same
Inventor: BEQUET ROMERO MÓNICA
IPC: A61P37/06
Filed: 2020-12-21
Abstract: Polypeptides comprising functional mutants of an isoform of the human vascular endothelial growth factor A (VEGF-A), folded in a non-natural re-arrangement of disulfide bonds, where the second and fourth cysteine of the polypeptide chain of the mutants are only found forming intramolecular bonds, while the seventh and eight cysteine of the mutants are only found forming intermolecular bonds. The invention further comprises antigenic preparations containing at least one of these polypeptides, and the pharmaceutical compositions comprising said antigenic preparations and vaccine adjuvants. The antigenic preparations according to the invention are used in the manufacture of a drug for the treatment of diseases whose progress is linked to increased angiogenesis, inflammation and immunosuppression, as well as for the restoration of the immune system.
Patent AU-2020479791-A1 (AU)
Title: Preparation method and system for recombinant adeno-associated virus and recombinant bacmid
Inventor: MEI TING
IPC: C12N15/35
Filed: 2020-12-18
Abstract: Provided are a preparation method and system for a recombinant adeno-associated virus (rAAV) and a recombinant bacmid. The method comprises: first reconstructing a recombinant bacmid containing a recombinant baculovirus genome that produces essential functional elements for an rAAV, at least one of the essential functional elements being inserted into the N-terminal or C-terminal of a locus of an essential gene of the recombinant baculovirus genome; and then transfecting the obtained recombinant bacmid containing the recombinant baculovirus genome that produces the rAAV into a host cell line for culturing to prepare an rAAV. Compared with recombinant baculoviruses obtained by conventional Tn7 recombinant preparations of recombinant bacmid, the recombinant baculovirus obtained by inserting a core element containing Cap, Rep and ITR into two sides of a baculovirus essential gene has a more stable rAAV serial passage production level in a cell and has a higher rAAV yield.
Patent AU-2021201926-A1 (AU)
Title: Tibial trial system for a knee prosthesis
Inventor: WAITE II DAVID W
IPC: A61F2/46
Filed: 2021-03-26
Abstract: An orthopaedic surgical instrument system for use during a surgical procedure to 
implant an orthopaedic knee prosthesis includes a tibial base trial component adapted to be 
positioned on a surgically-prepared proximal end of a patient's tibia and an insert 
component shaped to be received in an opening defined in the tibial base trial component.  
The insert component has a base plate and a central post extending upwardly from a 
superior surface of the base plate. A superior surface of the central post has a ramp surface 
defined therein, with the ramp surface inclining superiorly in the anterior-to-posterior 
direction.  
21/04/is2775RR nci 7R
Patent AU-2021204448-A1 (AU)
Title: Systems and methods of applying pragmatics principles for interaction with visual analytics
Inventor: SETLUR VIDYA R
IPC: G06F40/20
Filed: 2021-06-29
Abstract: A method uses natural language processing for visual analysis of a dataset by a 
computer. The computer displays a data visualization based on a dataset retrieved from a 
database using a first set of one or more database queries. The computer receives user input 
(e.g., keyboard or voice) to specify a natural language command related to the displayed data 
visualization. Based on the displayed data visualization, the computer extracts one or more 
independent analytic phrases from the natural language command. The computer further 
computes a set of one or more conversation centers associated with the natural language 
command based on the set of one or more analytic phrases. The computer then computes a 
set of analytical functions associated with the set of one or more conversation centers, 
thereby creating a set of one or more functional phrases. The device then updates the data 
visualization based on the set of one or more functional phrases.
Patent AU-2021209165-A1 (AU)
Title: Systems and computer-implemented methods for generating pseudo random numbers
Inventor: SHORTEN ROBERT BEDE
IPC: G06F17/17
Filed: 2021-07-26
Abstract: Described embodiments relate to systems and method for conditioning, de-biasing 
and/or whitening raw entropy data or for hashing data. The method comprises receiving 
data; determining at least a first algebraic number from the data; calculating at least one 
solution to one or more transcendental equations using the at least the first algebraic 
number as an input parameter value, wherein the one or more transcendental equations 
comprise a transcendental function that is capable of generating transcendental number 
outputs from algebraic number inputs; determining one or more sequences of pseudo 
random numbers based on the at least one solution; and determining an output based on 
the one or more sequences of pseudo random numbers. For example, the data may be 
received from a raw entropy source and comprise raw entropy to be transformed.  
Alternatively, the data may be data to be hashed and the output may comprise a hash of 
the data.
Patent AU-2021221741-A1 (AU)
Title: Permanent formwork for staircase construction
Inventor: BURNSIDE MALCOLM IAN
IPC: E04F11/09
Filed: 2021-08-25
Abstract: A permanent formwork structure 1 includes a pair of spaced apart elongate stringers 2,3 
having opposing inner faces 4,5 and which extends longitudinally between an upper end 7 
configured to attach to an upper landing and a lower end 6 configured to attach to a lower 
landing. The stringers 2,3 extend transversely a predetermined waist distance 12 between the 
lower and upper edges 9,10. A soffit 15 is disposed between the lower edges 9 of the 
stringers 2,3 which extends from or adjacent the lower end 6 of the stringers to, or adjacent 
to, the upper end 7. The structure 1 further includes a plurality of risers 20 longitudinally 
spaced apart between upper 7 and lower 6 ends of the stringers 2,3. The risers are disposed 
intermediate the inner faces 4,5 of the stringers where the risers 20 include a flange 22 at each 
side that extends a predetermined distance perpendicularly away from the flange inner face.  
The riser flanges 22 are configured to be disposed adjacent inner faces 4, 5 of the stringers 
2,3 such that the flanges 22 each include at least a pair of fastener apertures 25 configured to 
be disposed adjacent corresponding fastener apertures 26 in the stringers 2,3 for receiving a 
fastener 19 therethrough and securing the risers 20 to the stringers 2,3.
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Patent AU-2021224056-A1 (AU)
Title: Energy storage plant and process
Inventor: SPADACINI CLAUDIO
IPC: F01K25/08
Filed: 2021-02-15
Abstract: An energy storage plant (1 ) comprises a casing (5) for the storage of a working fluid different from atmospheric air, in gaseous phase and in pressure equilibrium with the atmosphere; a tank (9) for the storage of said working fluid in liquid or super- critical phase with a temperature close to the critical temperature; wherein said critical temperature is close to the ambient temperature. The plant (1 ) is configured to perform a closed cyclic thermodynamic transformation (CTT), first in one direction in a charge configuration and then in an opposite direction in a discharge configuration, between said casing (5) and said tank (9); wherein in the charge configuration the plant (1) stores heat and pressure and in the discharge configuration generates mechanical energy to drive a driven machine.
Patent AU-2021229312-A1 (AU)
Title: Signal connector system
Inventor: HACK HARVEY PAUL
IPC: H01R13/6464
Filed: 2021-02-02
Abstract: One example includes a signal connector system. The system includes a first connector comprising a first housing and first contacts formed from a self-passivating transition metal and configured to conduct an AC signal. The system also includes a second connector comprising a second housing and second contacts formed from the self-passivating transition metal and configured to electrically couple to a respective one of the first contacts to conduct the AC signal. The first and second housings can be coupled to enclose the signal connector and to create at least one fluid-filled channel between each of the electrically-connected first and second contact pairs in response to fastening the first and second connectors while submerged in a respective fluid to provide a resistive path in the at least one fluid-filled channel for providing signal isolation between each of the electrically-connected first and second contact pairs.
Patent AU-2021231880-A1 (AU)
Title: IRF modulator-expressing oncolytic viruses for treating cancer
Inventor: SARKAR SAUMENDRA N
IPC: A61K39/00
Filed: 2021-03-05
Abstract: The present disclosure provides oncolytic viruses expressing a modulator of interferon regulatory factors (IRFs), and compositions comprising thereof. The present disclosure further provides methods of using said oncolytic viruses and compositions for treating cancer, and for improving a subject's responsiveness to an immunomodulatory agent (e.g, an immune checkpoint inhibitor).
Patent AU-2021233835-A1 (AU)
Title: Modular electronic brake system
Inventor: BOULIVAN GUILLAUME
IPC: B60T13/14
Filed: 2021-03-10
Abstract: A brake system to couple between brakes and actuators provides a modular format that allows a plurality of braking modules (12, 14, 16, 18) to be coupled together at interfaces and coupled to other modules to handle a variety of different braking scenarios. Each braking module (12, 14, 16, 18) includes a housing (54, 56) forming a manifold for the delivery of fluid to the interfaces (90) of the modules for exchange between the modules. The braking modules (12, 14, 16, 18) include a hydraulic valve (68) coupled with a pressurized fluid source for delivering fluid to implement a braking function. The modules (12, 14, 16, 18) also include an electro-hydraulic valve (50, 52) configured for receiving electrical input signals and configured for delivering fluid from the pressurized fluid source to the hydraulic valve (68) at an actuation pressure that is proportional to the system pressure based on the levels of the received electrical input signals. Module interfaces (90) are positioned on respective sides of the housings (54, 56) for coupling the braking modules (12, 14, 16, 18) together and include a repeated pattern of apertures (100) for aligning between the braking modules (12, 14, 16, 18). The aligned apertures (100) are configured for passing fluid at the system pressure and fluid at the tank pressure between the plurality of braking modules (12, 14, 16, 18).
Patent AU-2021233949-A1 (AU)
Title: SWMM and EFDC coupling model-based regulation and storage project environmental effect assessment method and device
Inventor: XIA RUI
IPC: G06Q10/06
Filed: 2021-03-10
Abstract: Disclosed in the present invention are an SWMM and EFDC coupling model-based regulation and storage project environmental effect assessment method and device. Said method comprises: acquiring first geographic data for characterizing a pipe network runoff of a research area, second geographic data for characterizing pipe network parameters of the research area, third geographic data for characterizing a river distribution of the research area, and fourth geographic data for characterizing hydrodynamic water quality of a river of the research area; constructing a first SWMM and EFDC coupling model according to the described data, so as to obtain first output data for characterizing the water quality and the water volume before the implementation of a regulation and storage project; acquiring the position, scale, catchment area data, and project investment data of the regulation and storage project; adjusting an SWMM model according to the position, scale and catchment area data of the regulation and storage project; constructing a second SWMM and EFDC coupling model according to the adjusted SWMM model, so as to obtain second output data for characterizing the water quality and water volume after the implementation of the regulation and storage project; and assessing the environmental effect of the regulation and storage project according to the first output data, the second output data and the project investment data.
Patent AU-2021239772-A1 (AU)
Title: Pharmaceutical composition for cancer treatment comprising fusion protein including IL-2 protein and CD80 protein and anticancer drug
Inventor: JANG MYUNG HO
IPC: A61K38/17
Filed: 2021-03-18
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising a fusion protein including an IL-2 protein and a CD80 protein and an anticancer drug as active ingredients. A fusion protein including a CD80 fragment, immunoglobulin Fc, and an IL-2 variant, which is one embodiment of the present invention, can activate immune cells such as natural killer cells, and at the same time, can control the immune cell regulatory activity of regulatory T cells. In addition, when an anticancer drug is administered in combination with the fusion protein, cancer can be effectively suppressed. Accordingly, the pharmaceutical composition comprising the fusion protein including the IL-2 protein and the CD80 protein and the anticancer drug as active ingredients increases immune activity in the body and thus can be effectively used not only for cancer but also for infectious diseases, and is highly industrially applicable.
Patent AU-2021256799-A1 (AU)
Title: Anti-OX40 antibody and uses thereof
Inventor: YANG YIZHEN
IPC: A61P35/00
Filed: 2021-04-16
Abstract: Provided are an anti-OX40 antibody or antigen-binding fragment thereof, a preparation method thereof and the use for treating OX40-related diseases or conditions.
Patent AU-2021260953-A1 (AU)
Title: Method and system for using sensor data from rehabilitation or exercise equipment to treat patients via telemedicine
Inventor: MASON STEVEN
IPC: G16H20/00
Filed: 2021-04-22
Abstract: A method includes receiving treatment data pertaining to a user who uses a treatment device to perform a treatment plan. The treatment data includes at least one of characteristics of the user, measurement information pertaining to the user while the user uses the treatment device, characteristics of the treatment device, and the treatment plan. The method also includes generating treatment information using the treatment data and storing, for access at a computing device of a healthcare provider, the treatment information. The method also includes communicating with an interface, at the computing device of the healthcare provider, wherein the interface is configured to receive treatment plan input and modifying the treatment plan in response to receiving treatment plan input including at least one modification to the treatment plan.
Patent AU-2021264010-A1 (AU)
Title: Compounds and methods for modulating ATXN1
Inventor: ZHOU KEMING
IPC: A61P25/28
Filed: 2021-04-30
Abstract: Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of ATXN1 RNA in a cell or subject, and in certain instances reducing the amount of ATXN1 in a cell or subject. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom or hallmark of a neurodegenerative disease. Such symptoms and hallmarks include gait and limb ataxia, cognitive impairments, difficulty with speaking and swallowing, atrophy of the cerebellum and brainstem in magnetic resonance imaging (MRI), neurochemical abnormalities in the cerebellum and brainstem detected via magnetic resonance spectroscopy (MRS), and death within 10-15 years of symptom onset. Such neurodegenerative diseases include Spinocerebellar ataxia type 1.
Patent AU-2021269408-A1 (AU)
Title: Agricultural sprayer with real-time, on-machine target sensor
Inventor: HUMPAL RICHARD A
IPC: A01M7/00
Filed: 2021-11-18
Abstract: AGRICULTURAL SPRAYER WITH REAL-TIME, 
ON-MACHINE TARGET SENSOR 
ABSTRACT 
An agricultural applicator, that applies material to an agricultural field, includes an 
on-board, real-time image sensor that senses targets for the material to be applied. A controller 
controls applicators, such as nozzles or other applicators, to apply the material to the sensed targets 
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Patent AU-2021273179-A1 (AU)
Title: Downhole isolation valves with pressure relief
Inventor: NOSKE JOE
IPC: E21B34/08
Filed: 2021-05-11
Abstract: The present disclosure generally relates to a flapper valve including a pressure relief assembly. The pressure relief assembly is operable to activate when a pressure differential across the flapper approaches or exceeds a design pressure of the flapper.
Patent AU-2021285759-A1 (AU)
Title: Capillary-based pressure threshold sensor for liquids and methods and apparatuses using same
Inventor: BEGUIN STEVE
IPC: B60R21/01
Filed: 2021-05-25
Abstract: Capillary-based pressure threshold sensors are provided for liquids that exploit the properties of hydrophobic, superhydrophobic, oleophobic and amphiphobic porous membranes to detect when fluid passes through the membrane in the event of the pressure across the membrane rising above the breakthrough pressure of a fluid. Example implementations are provided of different configurations for a capillary-based pressure threshold sensor, and of how a capillary-based pressure threshold sensor is used in a medication delivery device or other fluid delivery devices to detect occlusion or other fluid flow condition.