baber/WOPTO huggingface dataset:
Patent IL-111580-A0 (IL)
Title: Melatonin derivatives for use in treating sleep disorders
IPC: C07D209/14
Filed: 1994-11-10
Abstract: The present invention provides a method of treating sleep disorders using various melatonin analogs. The invention further provides pharmaceutical formulations suitable for use in such method.
Patent IL-115242-A0 (IL)
Title: Recombinant mersacidin and a method for production
IPC: C12N15/09
Filed: 1995-09-11
Abstract: The present invention refers in particular to the structural gene sequence of the peptide antibiotic mersacidin. Sequencing revealed that premersacidin consists of an unusually long 48 amino acid leader sequence and a 20 amino acid propeptide part which is modified during biosynthesis to the mature lantibiotic. <MATH>
Patent IL-124604-A0 (IL)
Title: Crossbar/hub arrangement for multimedia network
IPC: H04L12/28
Filed: 1996-11-21
Abstract: A home network architecture has an internal digital network interconnecting devices in the home. Entertainment services are introduced into the network through network interface units that are coupled to an external network and to internal network. The network interface units are selectively directly connected by a direct circuit crossbar to set-top electronics so that video data, for example, may be directly provided from a network interface unit to the set-top electronics without jitter. A passive hub, which does not have packet routing capability, is then used to provide signal regeneration and re-transmission of other data over the network.
Patent IL-135047-A0 (IL)
Title: Container lid and implement
IPC: B65D85/72
Filed: 1998-09-18
Abstract: A lid (2) for a container (1) which lid comprises: a cover portion (5) adapted to extend over the container (1); an implement (3) adapted for use with contents (27) of the container, and a hinge (4, 6) connecting the cover portion (5) to the implement (3), wherein the implement is adapted to be rotated about the hinge (4, 6) into a storage position in which the implement lies against the cover portion. The cover portion may also be provided with an anti-tamper device or a tamper resistant or tamper proof arrangement.
Patent IL-135911-A0 (IL)
Title: Dna 19355 polypeptide, a tumor necrosis factor homolog
IPC: A61P35/00
Filed: 1998-11-18
Abstract: A tumor necrosis factor homolog, identified as DNA19355, is provided. DNA19355 polypeptide has apoptotic activity in mammalian cancer cells and may be involved in proinflammatory responses. Nucleic acid molecules encoding DNA19355, chimeric molecules and antibodies to DNA19355 are also provided.
Patent IL-137868-A0 (IL)
Title: Oligonucleotide mediated nucleic acid recombination
IPC: C12P21/02
Filed: 2000-01-18
Abstract: The invention provides a method of recombining a plurality of parental nucleic acids, comprising:hybridizing a library of oligonucleotides, synthesized to correspond to a plurality of parental nucleic acids, to at least one template nucleic acid;extending the hybridized library of oligonucleotides with a polymerase; and,ligating the resulting extended oligonucleotides with a ligase, thereby producing a recombinant nucleic acid.
Patent IL-144881-A0 (IL)
Title: The use of a brightener pigment in detergents or cleansers
IPC: C11D3/42
Filed: 2000-03-21
Abstract: The use of a brightener pigment comprising (a) a water-insoluble urea-formaldehyde resin and (b) a water-soluble fluorescent whitening agent. The brightener pigments are used for the purpose of improving the appearance of detergents, of compounds thereof, and of individual raw materials. The fluorescent whitening agent does not contact the goods being washed. Depending on the final use, the brightener pigment is subjected to a surface treatment.
Patent IL-154077-A0 (IL)
Title: New amidino derivatives and their use as thrombin inhibitors
IPC: C07D401/12
Filed: 2001-08-13
Abstract: There is provided compounds of formula I, wherein Y and R<1> have meanings given in the description, and pharmaceutically acceptable derivatives (including prodrugs) thereof, which compounds and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
Patent IL-158088-A0 (IL)
Title: Remedies for inflammatory bowel diseases
IPC: A61P43/00
Filed: 2002-02-18
Abstract: Antibodies against AILIM (also called ICOS and 8F4). were found to significantly suppress the onset of inflammatory bowel diseases (especially Crohn's disease and colitis (ulcerative colitis and such)), and exhibit a significant therapeutic effect against inflammatory bowel diseases.
Patent IL-166499-A0 (IL)
Title: Polymers of polyphenylene type process for preparing them membranes and fuel cell device comprising these membranes
IPC: B01D71/82
Filed: 2005-01-25
Abstract: Polymers with phenylene units, at least one of which has a lateral phenylene group substituted with a group or perfluorinated chain carrying a sulfonic acid, phosphonic acid or carboxylic acid group.  Polymers with phenylene units of formula (I) and (II), where at least one of which has a lateral phenylene group substituted with a group or perfluorinated chain carrying a sulfonic acid, phosphonic acid or carboxylic acid group. R1, R2, R3  =  H, halogen, alkyl, aryl, perfluoroalkyl or perfluoroaryl;  E  =  a single bond, -CO-, -P(O)- or -SO2-;  W1  =  arylene or perfluoroarylene;  A  =  -O-, -S-, -NH- or -NR9-;  R9  =  alkyl;  W2  =  aryl (substituted with F, -OSO2-aryl or -SO-aryl), or perfluoroaryl;  R4-R8  =  (a) H, halogen, OH, or -M(R10)3, (b) -P(O)(OR11)2, (c) aryl, aryloxy, -SO2-aryl, or alkyl-aryl, perfluoroalkyl or perfluoroalkylaryl (the last three optionally with in-chain O, N and/or S atom(s)), (d) perfluoroaryl or perfluoroaryloxy (optionally substituted with -SO3H, -PO3H2 or -COOH), or (e) an -SO3H, -PO3H2 or -COOH group, with the proviso that at least one of these groups is selected from -SO3H, -PO3H2, -COOH, perfluoroalkyl, perfluoroalkylaryl (optionally with in-chain O, N and/or S), perfluoroaryl and perfluoroaryloxy (optionally substituted as above), and that the acid groups may be in the form of their alkali metal salts; R9, R10  =  alkyl; and M  =  Si, Ge or Sn. Independent claims are also included for the following: (1) Method for the production of these polymers by reacting a base polymer comprising repeat units (II) with compound(s) of formula Ar-A2 (III); (2) Membranes containing sulfonated polymers as above; and (3) Fuel cells containing these membranes.  Ar  =  a phenyl group substituted with groups R4-R8 as above; and A2  =  OH, SH, NH2 or -NHR9, said group being capable of the nucleophilic substitution of a group attached to W2, i.e. F, -OSO2-aryl or -S(O)-aryl.
Patent IL-169368-A0 (IL)
Title: Cyclization process for substituted benzothiazole derivatives
IPC: C07D417/12
Filed: 2005-06-23
Abstract: The present invention relates to a process for preparation of amino substituted benzothiazole derivatives of formula I wherein R<SUP>1</SUP>, R<SUP>2 </SUP>and R<SUP>3 </SUP>are independently from each other hydrogen, lower alkyl, lower alkoxy or halogen; R<SUP>4 </SUP>is hydrogen, lower alkyl, lower alkyloxy, halogen, or is a five or six membered non aromatic heterocyclyl group, unsubstituted or substituted by lower alkyl or an oxo-group, or is -NR<SUP>5</SUP>R<SUP>6</SUP>, wherein R<SUP>5 </SUP>and R<SUP>5 </SUP>are independently from each other hydrogen, lower alkyl, -C(O)-lower alkyl, -(CH<SUB>2</SUB>)<SUB>n</SUB>O-lower alkyl or benzyl, opionally substituted by lower alkyl, or is an five or six membered heteroaryl group; R<SUP>1 </SUP>and R<SUP>2 </SUP>or R<SUP>2 </SUP>and R<SUP>3 </SUP>may form together with the corresponding carbon atoms a ring containing -O-CH<SUB>2</SUB>-O- or -CH-CH-CH-CH-; R is hydrogen or -C(O)R'; R' is a five or six membered non aromatic heterocyclyl group, five or six membered heteroaryl group or is aryl, which rings may be substituted by the groups, selected from lower alkyl, halogen-lower alkyl, lower alkoxy, cyano, nitro, -C(O)H, -C(O)OH or by pyrrolidin-1-yl-methyl; n is 1 to 4; or a pharmaceutically acceptable salt thereof, wherein the cyclization is carried out by the treatment of a compound of formula with sulphoxide/HBr/solvent to give the desired products of formula I for R is hydrogen (formula IA) or for R is -C(O)R' (formula IB)
Patent IL-172770-A0 (IL)
Title: Non sticky gum base for chewing gum
IPC: A23G4/00
Filed: 2005-12-22
Abstract: The present invention relates to a gum base formulation without polyvinyl acetate suitable for the production of a chewing gum with good sensory properties and good flavour release in combination with anti-adhesive properties in respect of teeth, dentures and the like typical of formulations containing polyvinyl acetate.
Patent IL-182881-A0 (IL)
Title: Methods for preventing and/or extinguishing fires background of the disclosure
Filed: 2007-04-30
Abstract: In the prevention of the spread of fires and for directly fighting fires, a cross­linked, water-swellable additive polymer in a vegetable oil dispersion is added to firefighting water. The additive has the properties of absorbing large quantities of water, high viscosity for adherence to vertical and horizontal surfaces, and retention of sufficient fluidity to be educted in standard firefighting equipment. The method of adding this additive to the firefighting water by eduction, pumping, or batch addition to the source water is also disclosed.
Patent IL-186396-A0 (IL)
Title: Portable air-purifying system utilizing enclosed filters
Filed: 2007-10-07
Abstract: A powered air-purifying respirator that includes an enclosure, defining a single contiguous enclosed interior, an inlet duct, including an inlet and a distribution portion, that guides ambient air to the interior of the enclosure, a plurality of filter canisters disposed within the interior of the enclosure, and a blower that forces air through the at least one inlet, into the interior of the enclosure and through the plurality of filter canisters to produce filtered air suitable for breathing. A valve controls the flow of ambient air through the inlet duct. A fluid dam, disposed in an air path between the inlet and the filter canisters prevents liquids from reaching the filter canisters. The enclosure is reinforced and is adapted to provide protection for the filter canister from flame and heat while the filter canister is in use. A recirculation valve recycles previously-filtered air back into the enclosure.
Patent IL-190040-A0 (IL)
Title: Method for the production of 5-fluoro-1,3-dialkyl-1h-pyrazol-4-carbonyl fluorides
Filed: 2008-03-10
Abstract: The present invention relates to a novel process for preparing known 5-fluoro-1,3-dialkyl-1H-pyrazole-4-carbonyl fluorides which can be used as starting materials for active fungicidal ingredients by a halex reaction.
Patent IL-191797-A0 (IL)
Title: Combination of azd2171 and pemetrexed
Filed: 2008-05-28
Abstract: The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of AZD2171 in combination with pemetrexed; to a pharmaceutical composition comprising AZD2171 and pemetrexed; to a combination product comprising AZD2171 and pemetrexed for use in a method of treatment of a human or animal body by therapy; to a kit comprising AZD2171 and pemetrexed; to the use of AZD2171 and pemetrexed in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.
Patent IL-217211-A0 (IL)
Title: Compounds for proteasome enzyme inhibition
IPC: C07K5/08
Filed: 2011-12-26
Abstract: Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.
Patent RO-130063-A0 (RO)
Title: Production and utilization of modern ovotransferrin ()
Inventor: PĂTRAŞCU IONEL VICTOR
IPC: C07K14/79
Filed: 2014-08-28
Abstract: The invention relates to a method for producing the ovotransferrin OTF-M specific for a target antigen, with applications in medicine. According to the invention, the method consists in the immunisation of the laying hens with an antigen consisting of a mixture of bacterial strains resistant to antibiotics, isolation of the white from the eggs produced by the immunised hens, followed by diluting it in a ratio of 1:1 with deionized water, adjusting the pH to 5, settling in two stages with ammonium sulphate and citric acid, followed by dialysis and lyophilisation.
Patent RO-131770-A0 (RO)
Title: Magnetite nanoparticles stabilized with (n-phosphonomethyl) imidodiacetic acid and doped with ions of rare earths
Inventor: NAN ALEXANDRINA EMILIA
IPC: A61K49/06
Filed: 2016-09-27
Abstract: The invention relates to magnetic nanoparticles stabilized with (N-phosphonomethyl) imidodiacetic acid and doped with ions of rare earths, characterized in that they have high values of the saturation magnetization, ranging between 68.5...71 emu/g, and, in their structure, they comprise ions of rare earths, in chelated form, from 0.5...3%, in mass percentage.
Patent RO-131950-A0 (RO)
Title: Collagen dressings enriched with polyphenols and polysaccharides, with regenerative effect in wound healing
Inventor: OPRIŢA ELENA IULIA
IPC: A61K35/32
Filed: 2016-11-03
Abstract: The invention relates to a composite dressing for treating skin diseases and to a process for preparing the same. According to the invention, the dressing consists of 40...70% collagen gel type I having an average molecular weight of 300...350 kDa, 10...30% chondroitin sulphate having an average molecular weight of 10...30 kDa, 10...25% hydroalcoholic extract of wormwood (Artemisia absinthium) containing 5...60 mg/ml polyphenols, 1...10 mg/ml polysaccharides and 0.05...1% riboflavin. The process, as claimed by the invention, consists in mixing 70...90 parts of composition consisting of a viscous solution of collagen type I and aqueous solution of chondroitin sulphate, with 30...10 parts of composition consisting of hydroalcoholic wormwood extract, at the ambient temperature, for 20...60 min, the mixture being then reticulated with 5...10 parts of riboflavin and conditioned as a biocompatible dressing.
Patent RO-132308-A0 (RO)
Title: Liquid dispenser
Inventor: CURCAN VASILE
IPC: B65D83/00
Filed: 2017-07-26
Abstract: The invention relates to a liquid dispenser which may use various types of common closed containers as a dispenser tank. According to the invention, the dispenser consists of a valve-type subassembly consisting of a membrane (1), an upper cover (2) provided with air passage orifices, a body (3) and a lower cover (4), provided with a nozzle for connecting it to the atmospherical environment, by means of a tube (9) and a nozzle (8), the entire subassembly, on which the support (5) is mounted, being introduced into the container (10), it is turned upside down, and upon the opening of the valve (7), under the effect of the vacuum created within the container (10), a membrane (1) allows the dislocated volume of liquid to be replaced with air, the liquid being thereby able to flow further on.
Patent RO-137543-A0 (RO)
Title: Fodder preparation for cows, intended for improving milk quality and quantity
Inventor: ŞTEF LAVINIA
IPC: A23K10/30
Filed: 2023-02-06
Abstract: The invention relates to a fodder preparation meant for dairy cows, in order to improve the milk quality and quantity. According to the invention, the fodder preparation is a homogeneous mixture of the following components expressed as weight percentage: 40...60% rapeseed grit, 20...40% sunflower grit, 20...40% wheat bran, 4...12 % protected vegetable fat; 4...6% calcium carbonate, 2...4% mono calcium phosphate, 2...4% sodium bicarbonate, 2...4% CLA, 0.4...0.8% active fodder yeast and 0.8...2% vitamin-mineral premix, an amount of 2.5 kg of this fodder preparation being incorporated in a ratio of 25...35% in the structure of a concentrate mixture meant for dairy cows, to lead to a milk yield increase of up to 25% and at the same time to a milk quality improvement materialized in the change of the amount of unsaturated fatty acids and the profile thereof.
Patent AP-2001002336-A0 (AP)
Title: A combination of a chamber and a piston, a pump, a motor, a shock absorber and a transducer incorporating the combination.
Inventor: VAN DER BLOM NICOLAAS
IPC: F04B53/14
Filed: 2000-04-25
Abstract: A combination of a piston and a chamber, wherein the chamber defines an elongate chamber having a longitudinal axis, the chamber having, at a first longitudinal position thereof, a first cross-sectional area thereof and, at a second longitudinal position thereof, a second cross-sectional area, the second cross-sectional area being 95 or less of the first cross-sectional area, the change in cross-sectional of the chamber being at least substancially continuous between the first and second longitudinal positions, the piston being adapted to adapt itself to the cross-section of the chamber when moving from the first to the second longitudinal position of the chamber. The piston may comprise an umbrella-like support structure or a fibre enforced deformable container coprising a foam or a fluid. The combination may be used in a pump, alinear actuator, a motor, or a shock absorber
Patent IE-900007-A1 (IE)
Title: Method and apparatus for preparing thermoplastic foam
IPC: C08L25/04
Filed: 1990-01-02
Abstract: Thermoplastic foam is prepared by a continuous process comprising melt mixing thermoplastic resin; pressurizing the resin melt; introducing blowing agent; cooling and depressurizing the resultant gel; and either foaming and forming the gel to form a solid foam or forming the gel to form a foamable composition. The process temperature is maintained substantially independently of the flow rate of the resin melt and gel at below that at which substantial depredation of the resin gel occurs. The process has particular application to rubber-modified polystyrene or rubbermodified polyethylene resin foam compositions containing a fire retardant.
Patent IE-900078-A1 (IE)
Title: Process and composition for the purification of amphotericin B
Inventor: MICHEL GERD W
IPC: C07H17/08
Filed: 1990-01-09
Abstract: A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.
Patent MW-5787-A1 (MW)
Title: Banking envelope
IPC: B65D27/04
Filed: 1987-07-31
Abstract: An envelope suitable for use in automatic teller machines is composed of two separate sheets of material forming a rectangular front panel l0 and a rectangular back panel 20 respectively. The front panel l0 and back panel 20 are adhesively secured along three marginal edges l2,l3,l4 and a closure flap l5 extends from the front panel l0 along its unsecured edge ll. The surface of the closure flap facing the back panel carries an adhesive substance l6 whereby the closure flap may be folded along the said unsecured edge ll over the back panel 20 and secured thereto to close and seal the envelope. The material of one of the panels is a translucent paper receptive to conventional printing processes and adapted to permit visual inspection of the envelope contents when the envelope is sealed.
Patent MA-26956-A1 (MA)
Title: Pyrimidine-2,4,6,triones inhibitrices de metalloproteinases.
Inventor: NOE MARK CARL
IPC: C07D417/12
Filed: 2003-04-21
Abstract: DEPOSANT Société dite : PFIZER PRODUCTS INC. REVENDICATIONS DE PRIORITES US 26 Octobre 2000 60/243,314 Pyrimidine-2,4,6-triones inhibitrices de métalloprotéinases La présente invention concerne des pyrimidine-2, 4, 6-triones inhibitrices de métalloprotéinases, de formule (I) dans laquelle X, Y, A, B et R1 répondent aux définitions figurant dans la description, et des compositions pharmaceutiques et méthodes de traitement de l'inflammation, du cancer et d'autres affections.
Patent MA-27756-A1 (MA)
Title: Derives heterocycliques renfermant de l'azote et medicaments contenant ces derives comme principe actif
Inventor: RENA NISHIZAWA
IPC: A61P29/00
Filed: 2005-10-03
Abstract: ABSTRACT Un composé représenté par la formule générale (I) suivante, l'un de ses sels ou ses solvates, ou l'un de ses promédicaments : (dont chaque symbole est défini dans la description.) Les composes représentés par la formule générale (I) sont utiles pour la prévention et ou le traitement de diverses maladies inflammatoires (asthme, néphrite, névropathie, hépatite, arthrite, polyarthrite rhumatoïde, rhinite, conjonctivite, colite ulcéreuse, etc.), maladies immunologiques (maladies autoimmunes, rejet d'organe transplanté, immunosuppression, psoriasis, sclérose en plaques, etc.), l'infection avec le virus immunodéficitaire humain (syndrome immunodéficitaire acquis etc.), maladies allergiques (dermatite atopique, urticaire, aspergillose bronchopulmonaire allergique, gastroentérite éosinophilique allergique, etc.), dommages ischémiques de ré-perfusion, syndrome de détresse respiratoire aigue, infection bactérienne s'accompagnant d'un choc, diabète, de métastase cancéreuse et ainsi de suite.
Patent MA-38981-A1 (MA)
Title: Caisse pour argent de poche planifie et depenses maitrisees
Inventor: ZOUINE ABDESLAM
IPC: E05B43/00
Filed: 2016-04-19
Abstract: Le rythme de la vie économique actuelle est difficile à suivre, on dépense tout ce qu'on gagne et parfois plus sans que ce soit utile. Dans le but de maintenir un niveau moyen des consommations mensuelles en se fixant un planning précis des utilités, je propose un moyen technique pour appliquer et maintenir cette idée. Ce moyen est destiné aux adultes qui cherchent à organiser leur vie économique; sous forme de cube de 200mm de coté, il renferme une série de ls tubes de 30 mm de diamètre fixées sur deux disques guidés en rotation. Chaque tube contient la somme estimée suffisante pour une journée par l'utilisateur. Elle peut être composée de billets, de pièces ou des deux ensemble. Une minuterie 24 heures, autorise le mécanisme à tourner d'un pas chaque 24 ou 12 heures (selon le choix) et par conséquent la charge du tube correspondant passe dans la caisse. D'autre part, un autre problème sérieux se pose aux parents dont l'âge des enfants nécessite de l'argent de poche journalier; on n'est pas prêt chaque matin à répondre à leurs besoins soit par oubli soit par insuffisance de liquide soit par autre raison. Pour cette catégorie, une caisse pour un ou pour deux enfants ensemble, est composée de cube en acier, en plastic ou en bois avec tube en acier de 30 mm de diamètre servant de magasin de pièces de monnaie. Selon le réglage ,24 ou 12 heures un disque se met en rotation pour alimenter la ou les deux caisses et s'arrêter pour attendre la nouvelle autorisation.
Patent MA-39128-A1 (MA)
Title: Composition pesticide
Inventor: ABREY ALEXANDER JOHN
IPC: A01N65/00
Filed: 2016-06-20
Abstract: L'invention concerne une composition pesticide contenant un stimulant alimentaire pour insectes et une quantité efficace de pesticides d'un ou plusieurs terpènes.