baber/WOPTO huggingface dataset:
Patent CA-2432075-A1 (CA)
Inventor: BAKER MATTHEW JOHN
IPC: C07D295/08
Filed: 2001-12-14
Abstract: The present invention relates to materials for extracting nucleic acid using  charge switch methods which involve, at a first pH, bringing the sample into  contact with a material which comprises an ionisable group, wherein the material has a positive charge at said first pH, such that nucleic acid is bound to the material; and releasing the nucleic acid at a second, higher, p H at which the charge on the material is negative, neutral or less positive. T he release of the nucleic acid occurs under mild conditions and the ionisable group is provided by a biological buffer, a polyhydroxylated amine, a detergent or surfactant, a carbohydrate, a nucleic acid base, a heterocyclic  nitrogen-containing compound, a monoamine, a biological dye, or a negatively  ionisable group, the pKa of which is between about 3.0 and 7.0 and a metal oxide which is positively charged at said first pH, and optionally also at said second pH.
Patent CA-2432995-A1 (CA)
Title: Immunogenic hla-a2 supermotif-restricted peptides
Inventor: SOUTHWOOD SCOTT
IPC: G01N33/569
Filed: 2002-01-29
Abstract: Methods to design vaccines which are effective in individuals bearing A2 supertype alleles are described. Single amino acid substitution analogs of known A2-supertype binding peptides, and large peptide libraries were utiliz ed to rigorously define the peptide binding specificities of A2-supertype molecules. While each molecule was noted to have unique preferences, large overlaps in specificity were found. The presence of the hydrophobic and aliphatic residues L, I, V, M, A, T, and Q in positon 2 of peptide ligands w as commonly tolerated by A2-supertype molecules. L, I, V, M, A, and T were tolerated at the C-terminus. While examination of secondary influences on peptide binding revealed allele specific preferences, shared features could also be identified, and were utilized to define an A2-supermotif. Shared features also correlate with cross-reactivity; over 70% of the peptides that  bound A*0201 with high affinity were found to bind at least 2 other A2- supertype molecules. Finally, the coefficients for use in the development of  algorithms for the prediction of peptide binding to A2-supertype molecules a re provided.
Patent CA-2433251-A1 (CA)
Inventor: MOGIL MELVIN SHELDON
IPC: A45C13/02
Filed: 2003-06-25
Abstract: A soft-sided insulated container assembly has a first insulated portion and a second insulated portion. The first and second insulated portions are generally box - shaped and are mounted in a back-to-back arrangement, such that they share a common wall. O ne of the portions has a receptacle in the nature of a removable, non-collapsible mold ed plastic tub, or bucket, that also has a mating, removable, mufti-positional divider mounted therein. The molded plastic receptacle is substantially rigid and functions to provide a stiff internal structure within the surrounding soft-sided wall structure. The other portio n is foldable, and can be moved between a collapsed, out of use position, to a.n expanded position for use when the main receptacle is not sufficiently capacious for all objects, or when different objects are better kept at different environmental conditions. The foldable portion is provided with securing straps to keep it neatly in the folded position when not in use.</S DOAB>
Patent CA-2433331-A1 (CA)
Title: Appareil permettant de faire passer de la pate a papier dans la caisse de tete d'une machine a papier ou equivalent
Inventor: HIETANIEMI MATTI
IPC: D21F1/66
Filed: 2001-12-19
Abstract: L'invention se rapporte à un appareil permettant de faire passer de la pâte à papier dans la caisse de tête (100) d'une machine à papier ou équivalent. Ledit appareil comporte un réservoir de désaération (11) dans lequel une pompe à vide (P¿0?) ou un autre dispositif fait régner un vide. Le réservoir de désaération (11) comprend un conduit d'entrée (10) permettant son alimentation en eau pour la table plate de fabrication. Ce réservoir de désaération (11) comporte également un conduit d'évacuation (12) dont l'extrémité d'évacuation est pourvue d'un trop plein (14) destiné à l'eau pour la table plate. Le trop-plein (14) de ce conduit d'évacuation (12) est situé en-dessous du réservoir de désaération (11) et il débouche dans un espace d'air libre, et le conduit d'évacuation (12) inclut un conduit secondaire (15a¿1?) destiné à un flux qui est amené à passer dans la caisse de tête (100).
Patent CA-2433360-A1 (CA)
Title: Mixer with pivotable bowl
Inventor: BADER BRIAN E
IPC: A21C1/02
Filed: 2002-10-24
Abstract: A mixer system including a bowl for receiving a material to be mixed, a mixer body having a rotatable output component, and a hinge. The bowl is pivotable about the hinge relative to the mixer body such the bowl can be pivoted between a loading/unloading position and a closed position relative the mixer body. The mixer system further includes a locking mechanism located at least partially on one of the bowl or the mixer body, the locking mechanism being normally biased into a locking position. At least a portion the bowl or the mixer body interacts with the locking mechanism to move the locking mechanism toward the release position to allow the bowl to move to the closed position, the locking mechanism being movable back toward the locking position when the bowl is in the closed position to retain the bowl in the closed position.
Patent CA-2437248-A1 (CA)
Title: Jnk inhibitor
Inventor: KAWAMOTO TOMOHIRO
IPC: A61P43/00
Filed: 2002-02-01
Abstract: A c-Jun N-terminal kinase inhibitor which contains an azole compound (I) substituted by a substituted nitrogenous aromatic group (provided that the compound (I) is not any of the compounds represented by the general formula) , (A) a salt thereof, or a prodrug thereof.
Patent CA-2437647-A1 (CA)
Inventor: GORDON KEVIN JR
IPC: B29C65/00
Filed: 2003-08-19
Abstract: Systems and methods for welding of parts are described.      In one embodiment, a method for ultrasonic welding of parts by means of an ultrasonic welding device including at least a generator, a converter, and a sonotrode based on a set curve of a time-dependent welding parameter appropriate to a welding connection meeting set requirements, where the welding duration corresponding to the set curve runs between a starting time t0 and an end time t e, wherein during welding of the parts an actual curve of the time-dependent welding parameter is measured, where in the period between t0 and t e the actual curve is compared with the set curve and, depending on the existing difference, at least one process parameter affecting welding is altered such that an equalization of set curve and actual curve occurs during further welding.
Patent CA-2438518-A1 (CA)
Title: Method of treating neurological diseases
Inventor: MADEN MALCOM
IPC: A61K35/76
Filed: 2002-02-15
Abstract: The invention relates to a method for treating a condition in a subject comprising administering an effective amount of an agent to said subject wherein said agent modulates one or more component(s) of the retinoid signalling pathway.
Patent CA-2439377-A1 (CA)
Inventor: BOYLE WILLIAM B
IPC: H04N5/775
Filed: 2002-02-22
Abstract: An audio/video apparatus (1) has an input port to receive a transport stream from a source of programs. The transport stream includes program data that is encoded and that represents at least one program to be presented to a user. A  storage device (8) is coupled to the input port and is configured to record the transport stream. A decoder (10) is configured to be coupled to the storage device (8) to obtain the encoded program data of the transport stream from the storage device (8) and to decode the encoded program data. A control device (16) is coupled to the storage device (8) and the decoder (10), wherein the control device (16) controls a variable rate with which the decoder receives the program data from the storage device (8).
Patent CA-2441460-A1 (CA)
Inventor: HEMPELMANN WILLI
IPC: E05F15/611
Filed: 2002-03-21
Abstract: The invention relates to a window or door structure comprising a frame, a sash that is displaceably mounted on the frame, and fitting modules located between the frame and the sash. According to the invention, a revolving control element, which can be driven by a motor and by a handle module, is provided for controlling the sash. Said control element is engaged with at least one fitting module in the different positions of the sash with regard to the frame and controls the course of movement of the fitting modules in such a manner that a well-defined execution of the sash movements is ensured by the sequential series of control movements of the control element or of a slide, which is driven by the motor and which can be connected to the control element.
Patent CA-2442372-A1 (CA)
Title: Proton exchange membrane (pem) for a fuel cell
Inventor: ZHANG ZHENGMING
IPC: H01M8/00
Filed: 2003-09-24
Abstract: A new PEM and fuel cell using that PEM are disclosed. The proton electrolyte membrane (PEM) comprises a polymer matrix and an ionically conductive ceramic material adapted to create a superconductive interface, the ceramic material being uniformly dispersed throughout the matrix. The polymer matrix is selected from the group consisting of proton exchange polymers, non-proton exchange polymers, and combinations thereof. The material is selected from the group consisting of beta alumina oxides, SnO2 (nH2O), fumed silica, SiO2, fumed Al2O3, H4SiW12O2 (28H2O), tin mordenite/SnO2 composite, zirconium phosphate-phosphate/silica composite.
Patent CA-2442790-A1 (CA)
Inventor: FORTH PETER JENS
IPC: C11D3/34
Filed: 2002-05-15
Abstract: The present invention relates to a pouch composition wherein the pouch is constructed from a water-soluble film and contains a composition comprising a cyclic hydrotrope. The present invention also relates to methods of producing such a pouch composition and to methods of treatment using such a composition. In addition, the present invention relates to the use of a cyclic hydrotrope for aiding the dissolution of a water-soluble pouch.
Patent CA-2444669-A1 (CA)
Title: Procedes de criblage de composes modulant l'activite des recepteurs d'hormones
Inventor: KUSARI JYOTIRMOY
IPC: G01N33/78
Filed: 2002-04-16
Abstract: La présente invention concerne des procédés permettant d'identifier un agent efficace modulant l'activité biologique d'un récepteur nucléaire d'hormones. Selon un procédé de l'invention, on analyse un complexe contenant un récepteur isolé à la recherche d'un état de modification perturbé par comparaison avec un état de modification témoin. La présence d'un état de modification perturbé permet d'identifier un agent efficace modulant l'activité biologique du récepteur nucléaire d'hormones.
Patent CA-2444966-A1 (CA)
Inventor: SIKORA LESZEK
IPC: A24C5/35
Filed: 2002-05-23
Abstract: In order to separate streams of multi-layered stacks of rodlike elements the rodlike elements are removed from the adjoining area of a horizontal conveyo r (3) or a channel positioned at an angle (1), in which the stack of rodlike elements becomes a passive stream to the area of the channel (1) or the horizontal conveyor (3), in which the stack becomes an active stream, and th e space taken up by the removed elements is equal to the volume of the appropriate sector of a cylinder of radius (r) corresponding to with (P) of the horizontal conveyor (3) and/or width (K) of the channel (1), whereas the walls of the cylinder which are parallel to the axis of the cylinder separat e the non-parallel streams. The said elements can also be shut in a recess (13 ) of cross section corresponding to the shape of a horizontal conveyor (3'') o r a channel (1'') made within a rotary cylinder, crosswise an axis of rotation (9''), whereas the axis of rotation (9'') of the cylinder is situated in the symmetry plane of the recess (13), moreover the axis of rotation (9'') of th e cylinder is situated in the symmetry plane of the horizontal conveyor (3'') and/or a channel (1''), whereas the shutting of the elements is realised by turning the cylinder. The valve device for separating streams consists of a valve (8) shaped as a cylinder of radius (r) or a sector of a cylinder positioned in the area of crossing the horizontal conveyor (3) and the chann el (1), whereas the axis of rotation (9) of the valve (8) is the axis of the cylinder and overlaps a line of intersection of a plane of an upper wall (6) of the horizontal conveyor (3) with a plane of a side wall (2) of the channe l (1), or the line of intersection of a plane of a lower wall (7') of a horizontal conveyor (3') with a plane of side wall (2') of a channel (1'), o r the axis of rotation (9'') of the valve (8'') is situated in the symmetry plane of the channel (1'') and/or the horizontal conveyor (3'') at a distanc e equal to or slightly bigger than the cylinder radius (r'') measured from a line of intersection of a plane of a side wall (2'') of the channel (1'') wi th a plane of a wall (6'') and/or (7'') of the horizontal conveyor (3''), where as within the cylinder there is through recess (13) the shape of which corresponds to the shape of the channel (1'') and/or the horizontal conveyor (3''), whereas the axis of rotation (9'') of the valve (8'') is situated in the symmetry plane of the recess (13).
Patent CA-2445635-A1 (CA)
Title: Centrifugal pump with reverse rotation protection integrated on the impeller blade
Inventor: BRESOLIN VALERIO
IPC: F04D13/06
Filed: 2003-03-27
Abstract: In a centrifugal pump (10) for liquids comprising an impeller casing (50) inside which a centrifugal impeller (40) is rotatably mounted including a hu b (42) from which a plurality or curved blades (44) delimited by two curved edges (44a,44b) extend, from one of the curved edges (44a) of the curved blades (44) a tab (48) extends on the side of the concavity of the blades (4 4) and is folded in the opposite direction to the blade (44) with respect to a radial plane.
Patent CA-2445668-A1 (CA)
Title: Securities analysis method and system
Inventor: ROSENDORF CHARLES HILLEL
IPC: G06Q40/04
Filed: 2002-03-28
Abstract: A system for analyzing financial data comprises a computer having a communication means for obtaining one or more points of data related to a security (210); means for storing the obtained data in a memory; a means for obtaining a second point of data related to the security and a means for storing the second data point in the memory; a means for comparing the data (202) from the obtained data points with the data of an additional data point related to the security, the additional data point being randomly chosen from data points, and a display means to display the compared data. The data points between which the randomly chosen data points prior to comparing the data, which is displayed in a format such as a table, spreadsheet export file, or graph (206). The compared data can be exported to a method of analyzing financial data. Using the present invention, an individual can track a securities portfolio, monitor its performance and make investment decision based on performance.
Patent CA-2447535-A1 (CA)
Inventor: UNGAR JEFFREY E
IPC: H01S5/12
Filed: 2002-06-05
Abstract: A semiconductor laser (10) has a distributed feedback laser section (12) and an amplifier section (14). The amplifier section (14) may be tapered to lower the optical power density particularly at an output facet (18) of the laser.  The semiconductor laser (10) also includes a reflective element (24) that reflects light (17) from the distributed feedback laser section (12) to the amplifier section (14). The reflective element (24) folds the optical path (Op) of the light beam (17). Folding the optical path (Op) allows the amplifier section (14) area to be increased without enlarging the semiconductor die size. The larger amplifier section (14) will increase the output power of the laser. Likewise the reflective element (24) will allow the semiconductor die size to be reduced without decreasing the optical power of the laser.
Patent CA-2447842-A1 (CA)
Title: Method for forming coating film on plastic substrate
Inventor: MATSUNO YOSHIZUMI
IPC: B05D7/00
Filed: 2003-10-31
Abstract: The present invention provides a method for forming a coating film on a plastic substrate which comprises: (1) coating the plastic substrate with an aqueous white primer (A) having a water content of 15 to 48 wt.% to form a coating film having an L* value of 80 or more, (2) heating the coating film of the primer (A) to adjust the water content of the film to 1 to 10 wt.% and the surface electrical resistivity value of the film to less than 10 9 /square, (3) electrostatically coating the coating film of the primer (A) with a thermosetting clear colored coating composition (B), (4) electrostatically coating the uncured coating film of the coating composition (B) with a thermosetting clear coating composition (C), and (5) baking the three-layer coating film to obtain a cured multilayer coating film having an N value of 8.5 or more.
Patent CA-2450042-A1 (CA)
Title: Improved ergonomic chair
Inventor: ZILLIG ERIC M
IPC: A47C1/0355
Filed: 2002-06-14
Abstract: An ergonomic chair (10) includes a four-bag linkage arrangement wherein a lower frame member (100) is provided with a rigid front support (130) and a rigid rear support (120) with a seat member (30) pivotably connected to the front support (130). A back rest (20, 200) has an upper support pivotably connected at an upper end of the rear support (120) of the lower frame. A link member pivotably connects at a first end to a rear support (120) of the seat member and at second end to a lower support of the back rest. This novel arrangement permits tilting movement of the backrest rearwardly relative to the lower frame member causing elevation of a rear portion of the seat member, permitting the feet to remain on the floor and alleviating pressure on the user's thighs, while rotation occurs closely coincident with the pivot axis of the user's hips ad while maintaining a generally uniform gaze line.
Patent CA-2450740-A1 (CA)
Inventor: WEBER ANN E
IPC: A61P15/16
Filed: 2002-07-05
Abstract: The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV  enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Patent CA-2451458-A1 (CA)
Title: Synthetic material sheet for stabilising coverings
Inventor: STROPPIANA FERNANDO
IPC: B32B27/12
Filed: 2003-11-28
Abstract: The present invention relates to a flexible sheet (1) having a composite structure for stabilizing coatings, comprising a first layer (2) of fibre material and a second layer (5) of fibre material impregnated by a first and a second impregnating material, respectively, and a body layer (3) set between said first layer and said second layer according to a general sandwich structure, where the body layer consists of a third material. The first and the second impregnating materials and the third material constituting the body layer are polymeric materials presenting a substantial affinity, so that the flexible sheet has a physically heterogeneous and chemically homogeneous structure.
Patent CA-2451807-A1 (CA)
Inventor: IMRAN MIR A
IPC: A61N1/372
Filed: 2002-06-20
Abstract: A capsule tracking system (160) is provided for tracking a capsule's (110) location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule (110). The method of use is also set forth.
Patent CA-2452952-A1 (CA)
Title: Compositions and medical devices utilizing bioabsorbable polymeric waxes
Inventor: NATHAN ARUNA
IPC: A61K9/16
Filed: 2003-12-12
Abstract: The present invention is directed to medical devices, pharmaceutical or agricultural compositions, and seeds, each containing a synthetic, bioabsorbable, biocompatible polymeric wax that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the polymeric wax having a melting point less than about 70 DEG C, as determined by differential scanning calorimetry.
Patent CA-2454761-A1 (CA)
Title: Secure method and system for handling and distributing digital media
Inventor: CHOW STANLEY T
IPC: G06F21/10
Filed: 2002-07-26
Abstract: A great deal of intellectual property is currenttly handled digitally, in th e from of audible, visual, or audio-visual files or data streams. With today's powerful electronic equipment and communication networks such as the interne t, this digital content can be reproduced flawlessly and distributed without control. While attemps have been made to protect such digital content, none of the existing protection techniques have been successful. The invention provides a system and method of protecting digital content by integrating th e digital content with an executable software package such as a digital media player, executing some sort of protection mechanism (such as password, watermark or encryption protection), and then encoding the software into a tamper-resistant form. In this way, the digital content can be used by initiating theexecutable software it was encoded with, but the content itsel f cannot be accessed, nor can the protection mechanism be cracked.
Patent CA-2456979-A1 (CA)
Inventor: JIANG CAI-ZHONG
IPC: C12N15/82
Filed: 2002-08-09
Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
Patent CA-2457011-A1 (CA)
Title: Treatment of glial tumors with glutamate antagonists
Inventor: NEDERGAARD MAIKEN
IPC: A61K31/4747
Filed: 2002-08-20
Abstract: The present invention relates to a method of treating glial tumors in a subject, which includes providing a glutamate antagonist or a NMDA receptor antagonist and administering the glutamate antagonist or NMDA receptor antagonist to a subject with a glial tumor of the brain or spinal cord under conditions effective to treat the glial tumor.
Patent CA-2457146-A1 (CA)
Inventor: YE TING TINA
IPC: A61L29/08
Filed: 2002-08-05
Abstract: The present invention relates generally to intravascular catheters for performing medical procedures. An intravascular catheter is disclosed comprising a multi-layered shaft having a shapable distal end. The shaft may comprise an inner liner; a second layer disposed over the inner liner, the second layer having a proximal segment and a distal segment corresponding to the shapable portion of the shaft; a third layer disposed over the second layer; and a fourth layer disposed over the third layer.
Patent CA-2457444-A1 (CA)
Inventor: HERREMANS ARNOLDUS H J
IPC: A61P25/14
Filed: 2002-09-17
Abstract: L'invention concerne un groupe de nouveaux dérivés de 1H-imidazole, des procédés de préparations desdits composés, et des préparations pharmaceutiques contenant au moins un desdits composés en tant que composant actif. Lesdits dérivés de 1H-imidazole sont des agonistes, des agonistes partiels ou des antagonistes puissants du récepteur cannabinoïde CB1, utiles pour le traitement de troubles psychiatriques et neurologiques ainsi que d'autres maladies impliquant la neurotransmission cannabinoïde. Les composés de l'invention sont représentés par la formule générale (1), dans laquelle R et R¿1?-R¿4? possèdent les significations données dans la description