baber/WOPTO huggingface dataset:
Patent EP-3233916-A2 (EP)
Title: Anticorps anti-acth humanisés et leur utilisation
Inventor: FELDHAUS ANDREW L
IPC: C07K16/42
Filed: 2015-12-18
Abstract: La présente invention concerne des anticorps et leurs fragments qui ont une spécificité de liaison à ACTH. Des modes de réalisation de l'invention concernent des fragments de liaison d'anticorps tels que décrits dans la description, comprenant les séquences des polypeptides V H , V L  et/ou CDR tels que décrits dans la description, et les polynucléotides les codant. L'invention concerne également des anticorps anti-ACTH et leurs fragments de liaison conjugués à au moins une fraction fonctionnelle ou détectable. L'invention concerne également des procédés d'élaboration desdits anticorps anti-ACTH et de leurs fragments de liaison. Des modes de réalisation de l'invention concernent aussi l'utilisation d'anticorps anti-ACTH et de leurs fragments de liaison à des fins de diagnostic, d'évaluation, de prévention et de traitement de maladies et troubles associés à ACTH, tels que l'hyperplasie surrénale congénitale (CAH), le déficit isolé en glucocorticoïdes (FGD), la maladie de Cushing, le syndrome de Cushing, la maladie de Parkinson, l'obésité, le diabète, les troubles du sommeil, la dépression, les troubles de l'anxiété, le cancer, l'atrophie musculaire, l'hypertension, l'hyperinsulinisme, les dysfonctionnements cognitifs, la maladie d'Alzheimer, la galactorrhée, les états liés au stress, les troubles cardiaques, le syndrome métabolique, l'hyperaldostéronisme, le syndrome de Conn et l'hyperaldostéronisme familiale.
Patent EP-3089048-A2 (EP)
Inventor: TAGUCHI AKINORI
IPC: G06F3/01
Filed: 2016-04-26
Abstract: A conversion device includes an input unit configured to input position information of a user's line of sight on a screen; an acquiring unit configured to acquire a character string included in a predetermined range from a position indicated by the position information, among character strings displayed on the screen; and a display control unit configured to display a list of character strings corresponding to readings including an input character as conversion candidates of the input character, among stored character strings, the list being displayed in response to the input character being input by the user. The display control unit increases a priority in a display order in the list for a character string that matches any of the acquired character strings, such that the priority is higher than that of a case where the character string does not match any of the character strings acquired by the acquiring unit.
Patent EP-3168078-A2 (EP)
Inventor: KOTANI HIROYUKI
IPC: B60L11/18
Filed: 2016-11-10
Abstract: A contactless power transmission system C is provided for supplying power contactlessly from a power transmission apparatus A to a power reception apparatus B. The power transmission apparatus A includes a high-frequency power source device 1 for outputting a constant high-frequency current, and power transmission units 21, 22, 23 having serial resonance circuits. The power reception apparatus B includes power reception units 31, 32, 33 having parallel resonance circuits. A power transmission coil Lt1, Lt2, Lt3 of the power transmission unit 21, 22, 23 and a power reception coil Lr1, Lr2, Lr3 of the power reception unit 31, 32, 33 are magnetically coupled. The power transmission units 21, 22, 23 are connected in series, while the power reception units 31, 32, 33 are connected in parallel. Power is transmitted from the power transmission unit 21, 22, 23 to the power reception unit 31, 32, 33 by magnetic field resonance.
Patent EP-3328207-A2 (EP)
Inventor: VAN ESBROECK MAURICE EDUARDUS THEODORUS
IPC: B26D7/06
Filed: 2016-07-12
Abstract: Cette invention concerne un dispositif de séparation de bréchet permettant de séparer un bréchet d'une carcasse de volaille, comprenant : - un couteau principal à bréchet comprenant :- une partie de coupe avant comprenant une pointe centrale avant, un bord de coupe avant gauche et droit qui divergent à partir de ladite pointe centrale avant, - une partie de coupe de branche de bréchet, comprenant un bord de coupe de branche gauche et droit, un point d'intersection d'une extension du bord de coupe de branche gauche et d'une extension du bord de coupe de branche droit étant disposé sur une ligne centrale parallèle à la direction de coupe à travers la pointe centrale avant, et le bord de coupe avant gauche et droit étant disposés à l'avant du bord de coupe de branche gauche et droit respectivement, vu dans la direction de coupe et vers l'extérieur par rapport à ladite ligne d'extension imaginaire à partir du bord de coupe de branche gauche et droit, respectivement.
Patent EP-3207955-A2 (EP)
Inventor: HARDING WESTON F
IPC: A61M39/26
Filed: 2007-11-01
Abstract: A vascular access device may include a body, housing, neck, and a septum with a substantially non-gaseous cross section. A method of operating a septum of a vascular access device may include providing a vascular access device in an external environment and actuating the septum without transferring a substantial amount of gas from within the device to the external environment of the device.
Patent EP-3545580-A2 (EP)
Inventor: GUARR THOMAS
IPC: H01M10/052
Filed: 2017-11-21
Abstract: L'invention concerne une cellule électrochimique rechargeable qui comprend: une électrode positive présentant un potentiel rechargé, une électrode négative et un électrolyte porteur de charge. La cellule électrochimique rechargeable comprend en outre un matériau actif de la structure suivante. (I)
Patent EP-3603813-A2 (EP)
Inventor: TOLOSA GONZÁLEZ EMILIANO GABRIEL
IPC: B04B11/04
Filed: 2018-03-28
Abstract: Fluid centrifuge and method for centrifuging a fluid with a centrifuge: the fluid centrifuge comprising: a frame, a rotor rotatably mounted about an axis of rotation, on the frame, and a cover for protecting the frame and the rotor, wherein the rotor comprises a unique holder intended to receive a cartridge with a fluid to be centrifuged, and the cover comprises an opening adapted to the size of the holder to allow insertion and removal of a cartridge; the application further comprises a method for centrifuging a fluid with a centrifuge, comprising: providing a fluid in a holder of a rotor of the centrifuge; subjecting the fluid to a predetermined centrifugation cycle; sensing the position of the holder relative to a centrifuge frame and stopping the rotor so that the holder is positioned in correspondence with an opening of the centrifuge.
Patent EP-3607058-A2 (EP)
Inventor: SANTAMARIA PEDRO
IPC: C07K14/725
Filed: 2018-04-05
Abstract: L'invention concerne une cellule isolée comprenant un récepteur de lymphocytes T recombiné (TCR) et un rapporteur dépendant de la voie du TCR, le récepteur de lymphocytes T recombiné étant spécifique pour un antigène pertinent pour une maladie lié à une molécule du CMH. L'invention concerne également des procédés d'utilisation de la cellule isolée comme dosage pour déterminer la fonction ou la puissance d'un complexe peptidique majeur d'histocompatibilité (pCMH)) couplé à une nanoparticule (pCMH-NP) qui peut être utilisé en tant que médicament pour le traitement d'une maladie auto-immune ou d'un cancer.
Patent EP-3609481-A2 (EP)
Inventor: DURING MATTHEW
IPC: A61K31/135
Filed: 2018-04-12
Abstract: Methods of treating developmental encephalopathies by administering compositions including ketamine, norketamine, or other derivatives of ketamine, or a pharmaceutically acceptable salt of any of the foregoing, are provided. The methods and compositions may be used to treat conditions such as Dravet syndrome.
Patent EP-3683244-A2 (EP)
Inventor: LEE MI SO
IPC: C08F2/50
Filed: 2018-09-20
Abstract: A solvent free-type photocurable resin composition for a polarizing plate protective layer includes an acryl-based prepolymer comprising a (meth)acrylate-based monomer as a polymerization unit; and an isocyanate-based crosslinking agent, wherein the acryl-based prepolymer is in a partially polymerized state, and viscosity at 25°C is greater than or equal to 50 cPs and less than or equal to 300 cPs. A polarizing plate including the solvent free-type photocurable resin composition, and an image display device including the polarizing plate is also provided.
Patent EP-3543684-A2 (EP)
Inventor: OSAKABE TAKESHI
IPC: G01N23/20
Filed: 2019-02-01
Abstract: An X-ray diffraction apparatus includes: an X-ray source 110; a first incident path letting the generated X-ray beam pass therethrough; a second incident path letting the generated X-ray beam be reflected by a multilayer film mirror and letting the reflected X-ray beam pass therethrough in parallel with the X-ray beam having passed through the first incident path; a movement mechanism moving the X-ray source 110, the first incident path, and the second incident path while preserving respective relative positions thereof; an incident slit 160 letting an X-ray beam to be incident on a sample S pass therethrough; and a sample support stage 165 supporting the sample S at a position fixed relative to the incident slit 160.
Patent EP-3563849-A2 (EP)
Inventor: ELMALEH DAVID R
IPC: C07H17/00
Filed: 2013-10-22
Abstract: The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising co-administering a therapeutically effective amount of a first compound, and a therapeutically effective amount of a second compound. In certain embodiments, the first compound or the second compound inhibits AB peptide polymerization; is an anti-inflammatory; improves cognitive function, mood, or social behavior; is associated with Tau or alpha-synuclein; or regulates amyloid peptide washout.
Patent EP-3656873-A2 (EP)
Inventor: MANDELL JEFFREY G
IPC: C12Q1/6844
Filed: 2017-05-10
Abstract: A method for enriching or amplifying a target nucleic acid including providing a system having a guide nucleic acid, and a Cas or Argonaute protein or a variant thereof. The guide nucleic acid contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid, and contacting the target nucleic acid with the system to form a complex.
Patent EP-3826609-A2 (EP)
Title: Expanding structured dosage form
Inventor: BLAESI ARON H
IPC: A61K9/28
Filed: 2019-02-21
Abstract: In this specification, a pharmaceutical dosage form comprising a three-dimensional structural framework of thin, solid elements surrounded by interconnected void space is disclosed. The elements comprise at least a drug, a water-absorptive, polymeric excipient, and a hydrophilic surface composition, so that upon immersion in a dissolution fluid the three-dimensional structural framework transitions from solid to viscous and expands in all dimensions. The disclosed dosage form enables better control of drug concentration in the blood stream, and improved therapeutic outcomes, among other advantages.
Patent EP-3793502-A2 (EP)
Inventor: ROBLIN FRANCOIS
IPC: A61G7/10
Filed: 2019-05-17
Abstract: Lève-patient destiné à lever et à abaisser un patient. Un câble ou une corde peut être utilisé en tant qu'élément de levage. La bobine enroule l'élément de levage sur des enroulements adjacents successifs. L'opérateur soulève le patient en poussant vers le haut la barre de transport, le patient ou l'élément de levage, et abaisse le patient en poussant vers le bas de tels éléments. Le lève-patient comprend un chargement et un déchargement automatiques pour effectuer une transition dans le lit ou hors du lit.
Patent EP-3902820-A2 (EP)
Inventor: GALLANT STUART
IPC: C07K14/535
Filed: 2019-12-27
Abstract: The invention provides for methods and processes for producing, isolating, and purifying modified proteins. In particular, the invention provides for the production, isolation and purification of PEGylated recombinant methionyl human granulocyte colony stimulating factor used for therapeutic purposes.
Patent EP-3847032-A2 (EP)
Inventor: CONTRACTOR MUSLIM
IPC: C09D11/101
Filed: 2019-09-04
Abstract: A method of forming an image on a substrate that includes applying a radiation curable analog ink composition by an analog printing method onto a surface of the substrate to form a coated substrate, applying a radiation curable inkjet ink composition by a digital printing method onto the coated substrate while the radiation curable analog ink composition is still wet to form a hybrid coated substrate, and exposing to electron beam radiation. A method of forming an image on a substrate that includes applying a radiation curable inkjet ink composition by a digital printing method onto a surface of the substrate to form a coated substrate, applying a radiation curable analog ink composition by an analog printing method onto the coated substrate while the radiation curable inkjet ink composition is still wet to form a hybrid coated substrate, and exposing to electron beam radiation.
Patent EP-3901332-A2 (EP)
Inventor: KWON MOON-JAE
IPC: C25D5/36
Filed: 2019-12-18
Abstract: The present invention relates to a zinc-nickel-alloy-electroplated steel sheet comprising a base steel sheet, and a zinc-nickel-plated layer which is located on at least one surface of the base steel sheet and which has a hairline pattern formed thereon, wherein the surface roughness of the surface of the base steel sheet, which forms an interface with the zinc-nickel-plated layer, is 0.7-1.0 µm on the basis of the average roughness (Ra) of the center line. According to the present invention, provided are: a zinc-nickel-electroplated steel sheet, which has a beautiful surface appearance after hairline processing, has better price competitiveness than a conventional stainless steel or a vinyl-coated steel, and can ensure high productivity in a coil polishing line; and a manufacturing method therefor.
Patent EP-3838183-A2 (EP)
Inventor: SHELTON IV FREDERICK E
IPC: A61B17/072
Filed: 2020-12-18
Abstract: A staple cartridge for use with a surgical instrument is disclosed. The staple cartridge comprises a cartridge body comprising a tissue-supporting surface, a staple cavity defined within the cartridge body, a staple removably positioned in the staple cavity, and a staple driver movably positioned within the staple cavity, wherein the staple driver is configured to support the staple. The staple cartridge further comprises a wedge sled translatable between a proximal end and a distal end of the staple cartridge, wherein the wedge sled is configured to move the staple driver from an unfired position to a fired position during a staple firing stroke, and a driver retention member configured to retain the staple driver in a retention position that allows for the wedge sled to be retracted after the staple firing stroke.
Patent EP-3956477-A2 (EP)
Inventor: DOR YUVAL
IPC: C12Q1/6886
Filed: 2020-04-16
Abstract: Methods of detecting DNA from a cancerous cell comprising receiving measurements of DNA methylation in at least one genomic region are provided. Arrays comprising at least 10 methylation specific oligonucleotides, wherein the methylation specific oligonucleotides are each reverse complementary to a genomic region are also provided.
Patent EP-4066410-A2 (EP)
Inventor: LUO JIANGHONG
IPC: H04J11/00
Filed: 2020-11-10
Abstract: Methods, systems, and devices for wireless communications are described. The described techniques provide for a first IAB node determining an adjustment to at least one parameter corresponding to a cell coverage of the first IAB node based at least in part on a geographic proximity of a cell relative to the first IAB node. For example, the first IAB node may determine to adjust the parameters based reference signal measurements, signal quality measurements (e.g., received from child nodes or user equipments (UEs)), etc. In another example, the first IAB node may receive an instruction from a central unit (CU) of the IAB network to adjust the at least one parameter. The first access node may transmit an indication of the adjustment to the at least one parameter. For example, the first access node may signal the adjustments to the CU, child IAB nodes, UEs and/or, other IAB nodes.
Patent EP-4027797-A2 (EP)
Inventor: GHANDI PERUMAL
IPC: C07K14/47
Filed: 2020-09-10
Abstract: La présente invention concerne de manière générale un composant lipidique qui comprend un sous-ensemble de lipides de lait et qui peut conférer à une composition un attribut conféré par du lait produit par un mammifère ou une graisse de lait. La présente invention concerne en outre des procédés de production d'un tel composant lipidique. La présente invention concerne en outre des compositions qui comprennent un tel composant lipidique, et leurs procédés de production.
Patent EP-4082562-A2 (EP)
Inventor: BEQUET ROMERO MÓNICA
IPC: A61P37/06
Filed: 2020-12-21
Abstract: Polypeptides comprising functional mutants of an isoform of the human vascular endothelial growth factor A (VEGF-A) folded in a non-natural re-arrangement, where the second and fourth cysteine of the mutant's polypeptide chain is only forming intramolecular bridges, while the seventh and eight are only part of intermolecular bonds. The invention further comprises antigenic preparations containing at least one of these polypeptides, and the pharmaceutical compositions comprising such antigenic preparations and vaccine adjuvants. The antigenic preparations according to the invention are used in the manufacturing of a drug, for the treatment of diseases related to the increment of angiogenesis, inflammation, and immunosuppression, as well as for the restoration of the immune system.
Patent EP-4035920-A2 (EP)
Title: Power split all-wheel drive system
Inventor: AULIN HANS
IPC: B60K17/356
Filed: 2021-09-23
Abstract: The present disclosure refers to an all-wheel drive system (10) for a vehicle (12), comprising:- an electrical motor (24) being connected to a first axle (26) of a planetary gear set (28) arranged at an output side (30) of a vehicle gearbox (32), and- a second axle (34) of the planetary gear set (28) being connected or connectable to the gearbox output shaft (36) or to ground (G) by a coupling (I),- while a third axle (38) of the planetary gear set (28) is connected or connectable to the front axle (14) of the associated vehicle (12); and further to an all-wheel drive system (10) for a vehicle (12), comprising:- a differential (56) arranged between a vehicle gearbox (32) and a front (14) and rear axle (16) of an associated vehicle (12),- a first planetary gear set (28) having a planetary gear set output (58) being connected to one of the differential outputs (60), and- a second planetary gear set (62) having a planetary gear set output (64) being connected to the other one of the differential outputs (68), whereinsaid first (28) and second planetary gear set (62) are sharing a common ring wheel (44), and an electrical motor (24) is electively connectable to one of the planetary gear sets (28) or to a gearbox output shaft (36) by means of a coupling (I).
Patent EP-4075025-A2 (EP)
Inventor: TRIMMER GARETH
IPC: F16H57/02
Filed: 2022-04-11
Abstract: An axle assembly for a working machine is provided. The axle assembly has an axle housing comprising a central portion housing a gear, wherein the gear is configured to rotate about an axis and is configured to be partially disposed in a lubricant reservoir, and at least one arm portion extending from the central portion, the arm portion housing at least one driveshaft. The axle assembly further comprising a conduit assembly configured to direct lubricant from the central portion to the arm portion, the conduit assembly comprising a lubricant catcher having an inlet disposed in an interior volume of the central portion.
Patent EP-4090137-A2 (EP)
Inventor: FLACHENECKER CLAUS
IPC: H05G1/06
Filed: 2022-04-22
Abstract: The electron beam (B) is typically dynamically steered after its generation on the path to the target. The steering is performed by one or more source coils (132S, 132N). These coils produce the magnetic field outside the vacuum vessel allowing air/water/oil cooling to remove undesired heat. The magnetic field is then picked up inside the vacuum vessel with pole pieces and guided towards the region where the magnetic field is needed to steer the electron beam.
Patent EP-4086159-A2 (EP)
Inventor: ALLEN CHRISTOPHER K
IPC: B63B35/44
Filed: 2022-05-05
Abstract: A motion absorbing system and method for a structure includes the coupling of a container to a structure. The container has a liquid disposed therein wherein a ullage is defined above a surface of the liquid. An elastic element is positioned in the liquid. The elastic element has a natural frequency tuned to damp motion of the liquid.
Patent EP-4151487-A2 (EP)
Inventor: YU NING
IPC: B60W30/18
Filed: 2022-12-20
Abstract: A method and an apparatus for controlling lane changing, an electronic device and a storage medium. The implementation solution includes: predicting (S410) a target pose of a vehicle changed to a second lane based on a current pose of the vehicle on a first lane in response to a trigger of changing the vehicle from the first lane to the second lane; and determining (S420) a lane changing preparation pose of the vehicle on the first lane based on the target pose and at least one parameter of the vehicle.
Patent EP-4301847-A2 (EP)
Title: Stroma-free nk cell differentiation from human pluripotent stem cells
Inventor: JING RAN
IPC: C12N5/0783
Filed: 2022-03-04
Abstract: The technology described herein is directed to stromal-free methods of NK cell differentiation. Also described herein are cells differentiated using stromal-free methods and compositions comprising such cells. In some embodiments, the cells can be genetically modified. In some embodiments, the cells or compositions comprising said cells can be administered to a patient to treat cancer or as a cellular replacement therapy to treat a condition.
Patent EP-4253205-A2 (EP)
Inventor: KOIZUMI EICHI
IPC: B62D55/12
Filed: 2021-01-26
Abstract: A crawler type traveling body (10) includes a drive wheel (13), an in-wheel motor (14) incorporated in the drive wheel (13), a plurality of rotating wheels (15a, 15b) disposed below the drive wheel, a crawler (11), and a tensioner (25). The crawler (11) is wound around the drive wheel (13) and the rotating wheels (15a, 15b) and configured to be rotated by the drive wheel (13). The tensioner (25) is coupled to a drive shaft (141) of the in-wheel motor (14) and configured to press the drive wheel (13) against the crawler (11) and apply tension to the crawler (11).
Patent EP-4246668-A2 (EP)
Title: Battery cell assembly and battery module including same
Inventor: YOO TAK KYUNG
IPC: H01M10/658
Filed: 2023-03-13
Abstract: A battery cell assembly includes a first battery cell, a second battery cell disposed to face the first battery cell, a protective member disposed between the first battery cell and the second battery cell, and a support member coupled to at least one side of the protective member and supporting the protective member. The protective member includes a heat insulating member preventing heat propagation between the first battery cell and the second battery cell.
Patent EP-4236021-A2 (EP)
Inventor: Sur Rajesh
IPC: H02J7/04
Filed: 2018-09-18
Abstract: An intelligent charger for an aerosol delivery device includes a housing, first and second connectors connected to the housing, and a power management integrated circuit (PMIC). The first connector is configured to engage a control body of the aerosol delivery device. The second connector is configured to engage a power supply, which is connected with and controllable to provide power to recharge a power source of the control body when the first connector is engaged with the control body and the second connector is engaged with the power supply. The PMIC is configured to obtain measurements of a temperature of the power source, compare the temperature to a predetermined range of temperatures, and control the power provided by the power supply to maintain the temperature within the predetermined range of temperatures during recharge.