Patent DE-19821613-A1 (DE)
Title: Transgenic sulfonylurea-tolerant sugar beet useful in crop protection
Inventor: STUEBLER HERMANN
IPC: A01H5/12
Filed: 1998-05-14
Abstract: Transgenic sugar beet (including seeds, propagative material and cells) which is tolerant to sulfonylurea herbicides is new. The sugar beet is tolerant to sulfonylureas A1)-A18:  A1) compounds (I) or their salts;  A2) compounds (II) or their salts;  A3) compounds (III), their N-oxides or salts;  A4) amidosulfuron;  A5) ethoxysulfuron;  A6) triasulfuron;  A7) metsulfuron;  A8) tribenuron; A9) flupyrsulfuron;  A10) nicosulfuron;  A11) rimsulfuron;  A12) primisulfuron;  A13) prosulfuron;  A14) sulfosulfuron;  A15) oxasulfuron;  A16) ethametsulfuron;  A17) imazosulfuron;  A18) compounds (IV).  Q  = O; S; or NR<4>;  Y  = CH or N;  R  = H; alkyl optionally substituted with halo, alkoxy, thioalkyl, CN, alkoxycarbonyl or alkenyl; alkenyl; alkynyl; cycloalkyl optionally substituted with alkyl, alkoxy, alkylthio or halo; cycloalkenyl; phenyl-alkyl optionally ring-substituted with 12 groups; or a group of formula (a)-(j):  X  = O; S; SO; or SO2; R<1> = H or alkyl;  R<2> = H; halo; or alkyl or alkoxy optionally substituted with halo or alkoxy;  R<3>  = H; halo; alkyl, alkoxy or alkylthio optionally substitut ed with halo, alkoxy or alkylthio; NR<5>R<6>; cycloalkyl; alkenyl; alkynyl; alkenyloxy; or alkynyloxy;  R<4>  = H; alkyl; or alkoxy;  R<5> and R<6>  = H; alkyl; alkenyl; haloalkyl; or alkoxy; R<1>a   = CO-Qa-R8;  R<2>a and R3a  = H or alkyl; R<4>a = H; alkyl; OH; or alkoxy;  R<5>a  = alkylsulfonyl; CHO; alkyl-CO optionally substituted with halo; alkoxy-oxalyl; cycloalkyl-CO; -C(W)-T-R<9>; -C(W)-NR<10>R<11>; or -C(W)-N(R<12>)2;  W and T  = O or S;  R<9>  = H or alkyl optionally substituted with halo, alkoxy, alkylthio, alkoxy-CO or alkyl-CO;  R<10> and R<11>  = H; alkyl optionally substituted with halo; alkenyl; or alkynyl (at least 1 of R<10> and R<11> is H);  N(R<12>)2 forms a 5-6 membered heterocycle optionally containing a further N or O, S, SO or SO2 and optionally substituted with alkyl or oxo; Qa = O; S; or NR13;  R6a = H; alkyl; alkoxy; or halo; R8 = alkyl optionally substituted with halo; alkenyl; or alkynyl; A = group of formula (k): Xa = halo; Me; Et; OMe; OEt; OCF2H; CF3; or OCH2CF3; and Ya = Me; Et; or OMe or OEt optionally substituted with halo; or Xa = Me; Et; or OMe or OEt optionally substituted with halo; and Ya = halo; Me; Et; OMe; OEt; OCF2H; CF3; or OCH2CF3; Z = CH or N; R7 = H or Me; R13 = H; alkyl optionally substituted with halo; alkenyl; or alkynyl; R1 = H; halo; alkyl optionally substituted with halo; alkoxy; or alkylthio;  R2 = H or Me; R3 = Me or OMe; A1 = -NR4R5; R4 = H; alkyl optionally substituted with halo, alkoxy, alkenyloxy, alkynyloxy or alkylthio; R5 = H; alkyl optionally substituted with halo, alkoxy, alkenyloxy, alkynyloxy or alkylthio; or C(O)R6; R6 = H; alkyl or cycloalkyl optionally substituted with halo or alkoxy; alkenyl optionally substituted with halo; phenyl, benzyl or naphthyl optionally substituted with 15 groups; or OR7; R7 = alkyl optionally substituted with halo, alkoxy, cycloalkyl, CN, COOR19 or CONR26R27; alkenyl or alkynyl (each optionally substituted with halo);  oxetan-3-yl; cycloalkyl optionally substituted with halo, alkyl or alkoxy; or phenyl, benzyl or naphthyl optionally substituted with 14 groups; R8 = H; alkyl; alkenyl; alkynyl; or oxetan-3-yl; R9-R12, R16, R17, R20, R21 and R23-R27 = H; alkyl; alkenyl; or alkynyl; or R10 and R20 = -C(O)-X5-alkyl or -C(O)-alkyl (each optionally substituted with halo); or R10 and R11 or R12 and R13 or R16 and R17 or R20 and R21 or R23 and R24 or R25 and R9 or R26 and R27 together form alkylene optionally partly interrupted with O or NR14; R14 = H; alkyl; alkenyl; or alkynyl; R15 and R29 = alkyl or haloalkyl; R18 and R30 = alkyl substituted with COOR28; R19, R22 and R28 = H or alkyl; X1 and X3 = S; SO; or SO2; X2 and X4 = O or S; X5 = O or NR14.  The full definitions are given in the DEFINITIONS (Full Definitions) Field. Independent claims are also included for: a) the preparation of the transgenic sulfonylurea-tolerant sugar beet; and b) the control of undesired plant growth in transgenic sulfonylurea-tolerant sugar beet crops by applying to the beet (including seeds and propagative material) or to their cultivation area a sulfonylurea A1)-A18) alone or as a herbicide.