baber/WOPTO huggingface dataset:
Patent MX-PA03009805-A (MX)
Title: Compaction process for manufacture of sodium phenytoin dosage form.
Inventor: ASHLESH KALYANBHAI SHETH
IPC: A61K47/12
Filed: 2002-04-25
Abstract: A process for the roller compaction and manufacture of a pharmaceutical formulation comprises the steps of adding sodium phenytoin to a vessel of a blender and adding at least one excipient to the vessel. The mixture is blended and transferred to a roller compactor, where pressure is applied to the blend of sodium phenytoin and excipient. Next, the resultant compaction is milled to form a granulation, which is blended a second time and is suitable for further processing into a dosage form. Preferably, the excipients include magnesium stearate, sugar, lactose monohydrate, and talc. In an alternative embodiment, talc is added immediately prior to the granulation being blended for a second time.
Patent MX-PA04000762-A (MX)
Title: Pile weatherstripping and methods of making same.
Inventor: DAVID M LOUGHNEY
IPC: E06B7/22
Filed: 2002-05-24
Abstract: Pile weatherstripping has a pile of yarn segments (20) which are attached to a flexible plastic backing strip (1) by ultrasonic welding (21) of the pile thereto. Loops of the yarn (20) are captured in a channel (16) on one side of the backing strip. This channel is formed by extracting flanges (15) from the backing strip by a cutting tool (Fig. 8) having a pair of chiseled cutting surfaces (2a, 2b) tapering inwardly and spaced from each other. The backing strip is preferably wound on a capstan (9) in a plurality of turns so as to feed the strip past the cutting tool. The cutting tool leaves notches along the channel on the outside of the flanges. The base of the channel is unaffected by the cutting tool and presents a stress-free surface at which the yarn is welded. The notches improve the bending strip flexibility of the backing so as to facilitate insertion of the weatherstrip into a T-slot (22).
Patent MX-PA04002003-A (MX)
Title: Low visual impact monopole tower for wireless communications.
Inventor: BOB ELLIOT
IPC: H01Q3/30
Filed: 2004-03-02
Abstract: An antenna system incorporating at least two antennas circumferentially arranged with a side-by-side relationship about a monopole tower. The main beam direction of the radiation pattern emanating from each antenna may be remotely adjusted in elevation and/or azimuth. The main beam direction of the radiation pattern emanating from adjacent antennas may be varied independently. The antennas may be partitioned in one or more vertically-spaced groups each of which is arranged about a circumference of the monopole tower.
Patent MX-PA04003873-A (MX)
Title: Method and apparatus for controlling data rate in a wireless communication system.
Inventor: PAUL E BENDER
IPC: H04J13/00
Filed: 2002-10-16
Abstract: In one disclosed embodiment, communication between a mobile unit and a base station is performed at a data transfer rate selected from, for example, a finite set of HDR data transfer rates. Meanwhile, the mobile unit continually computes a moving average of the data transfer rates. The mobile unit also ascertains a supportable data rate for receiving data. The supportable data rate can be selected from a finite set of HDR data transfer rates. In order to maintain the moving average of the data transfer rate within a specified range, the mobile unit transmits maximum data rate requests or null data requests to the base station. The maximum data rates requested by the mobile unit are equal to or lower than the supportable data rate.
Patent MX-PA04004187-A (MX)
Title: Method of administering a thymosin alpha 1 peptide.
Inventor: ALFRED R RUDOLPH
IPC: A61P37/04
Filed: 2002-11-01
Abstract: A Thymosin alpha 1 (TA1) peptide is administered to a patient in need of immune stimulation so as to substantially continuously maintain an immune stimulating-effective amount of the TA1 peptide in the patient. The administration method may be by continuous infusion.
Patent MX-PA04006795-A (MX)
Title: Through-dyeing of cotton warp yarns with indigo.
Inventor: BOCK ALEXANDER
IPC: D06B3/04
Filed: 2004-07-13
Abstract: The present invention relates to a process for through-dyeing of cotton warp yarns with indigo in an indigo dyeing range, which comprises dyeing in one pass at a dyeing temperature of 30 to 90 DEG C. and an indigo concentration of 10-60 g/l.
Patent MX-PA04008945-A (MX)
Title: Multi-layer focusing method and apparatus therefor.
Inventor: KIL-SOO JUNG
IPC: H04N21/482
Filed: 2003-01-18
Abstract: Provided are a method for efficiently navigating a plurality of contents which are reproduced in a device for reproducing interactive contents, for example, a computer, a DVD player, a PDA, or a cellular phone, by using a device having a limited number of input keys, and a method therefor. The provided multi-layer focusing method includes (a) allotting focusing layer values to contents elements to form focusing layers, (b) providing the contents elements included in any one focusing layer to a user, and (c) moving the focusing when a command to move the focusing is input from the user.
Patent MX-PA04009827-A (MX)
Title: Finger-mounted electrokinetic delivery system.
Inventor: DEROUIN JAMES O
IPC: A61N1/32
Filed: 2003-04-07
Abstract: An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device (10) shaped to conform with the shape of a portion of an individual's finger (71) from a tip thereof to a location past the first finger joint. A self-contained power source (25) is carried by the device (10) and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger (71).
Patent MX-PA04012433-A (MX)
Title: Consumer scrubbing wipe article and method of making same.
Inventor: TIMOTHY J LINDQUIST
IPC: D04H1/46
Filed: 2003-04-18
Abstract: A consumer scrubbing wipe article including a nonwoven substrate and a texture layer. The nonwoven substrate has a dry basis weight of less than about 300 g/m2, and thus promotes easy, comfortable handling by a user. The texture layer is a non-crosslinked, abrasive resin-based material that is printed onto at least one surface of the nonwoven substrate. In this regard, the texture layer covers less than an entirety of the substrate surface and extends at least 50 microns outwardly beyond the substrate surface to which it is printed. This characteristic ensures that the scrubbing wipe article has a distinct scrubbyness attribute.
Patent MX-PA05000063-A (MX)
Title: Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs.
Inventor: BRINES MICHAEL
IPC: C12N15/87
Filed: 2003-07-01
Abstract: Methods and compositions are provided for protecting or enhancing a responsive cell, tissue, organ or body part function or viability in vivo, in situ or ex vivo in mammals, including human beings, by systemic or local administration of an erythropoietin receptor activity modulator, such as an recombinant tissue protective cytokine.
Patent MX-PA05000343-A (MX)
Title: Seasoning treatment system.
Inventor: TATSUOKA MASAHIKO
IPC: A23L27/00
Filed: 2004-06-25
Abstract: A seasoning treatment system (2) capable of seasoning uniformly and providing excellent cleaning property, comprising a seasoning spray device (20) and a vertical pillow bag packaging machine (30). The seasoning spray device (20) sprays powder seasoning to be adhered to supplied intermediate products (X...X) from the end part (22b) of a second pipe (22) as a spray port. The vertical pillow bag packaging machine (30) packages seasoned products (X2...X2) to which the powder seasoning is adhered in a bag-like packaging material (Fc). The end (22b) of the second pipe (22) as the spray port is disposed to be positioned in the bag-like packaging material (Fc).
Patent MX-PA05002101-A (MX)
Title: Multi-part closure device.
Inventor: REYNOLDS GARY M
IPC: B65D33/30
Filed: 2003-05-29
Abstract: The invention relates to a multi-part closure device or clip (20) having a first and a second clip body component (22, 24). The clip has a releasable latch (26) at one end, a rigid connection (32) at an opposite end, and at least one flexible neck (30) disposed between the releasable latch (26) and the rigid connection (32). The flexible neck (30) hinges one clip body component with respect to the other clip body component while enabling the rigid connection (32) to remain stationary with respect to both clip body components (22, 24).
Patent MX-PA05002971-A (MX)
Title: Vehicle electronic key system.
Inventor: TAKESHI KONNO
IPC: B60R25/01
Filed: 2003-09-25
Abstract: A control device (14) includes means for outputting a request signal (Sr) to an electronic key (12) in response to the ON operation of a predetermined switch (start switch (70)) among a plurality of switches (winker switch, horn switch, etc.) arranged in the vicinity of a user who has sat on the driver seat of the vehicle (100B) (request signal generation means (80), a transmission circuit (46), and a transmission antenna (72)), means for detecting a response signal (Sa) from the electronic key (12) (a reception circuit (44) and response signal matching means (82)), and monitoring means (84) for outputting a lock release instruction to an actuator (64) when the response signal (Sa) shows that the request is from a regular user.
Patent MX-PA05004440-A (MX)
Title: Crystals of insulin analogues and method for the production thereof.
Inventor: HARALD BERCHTOLD
IPC: A61K38/00
Filed: 2003-10-16
Abstract: The invention relates to crystals of an insulin analogue, in which asparagine (Asn) in position B3 of the B chain is replaced by a naturally occurring basic amino acid residue, and at least one amino acid residue in positions B27, B28 or B29 of the B chain is replaced by another naturally occurring neutral or acid amino acid residue. According to the invention, phenylalanine (Phe) can optionally be absent in position B1 of the B chain, and the crystals exist in space group R3 (Nr. 146) with cell axes A=81.5 ¦ ¦ 1 ¦ and C=33.3 ¦ ¦ 1 ¦. The invention also relates to the production and use of said crystals, and to a pharmaceutical composition containing these crystals.
Patent MX-PA05005558-A (MX)
Title: CHIMERIC AND HUMANIZED ANTIBODIES TO alpha5beta1 INTEGRIN THAT MODULATE ANGIOGENESIS.
Inventor: URSULA JEFFRY
IPC: C07K16/28
Filed: 2003-11-26
Abstract: The present invention provides chimeric and humanized antibodies that specifically recognize alpha5beta1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.
Patent MX-PA05006113-A (MX)
Title: Targeting single epitopes.
Inventor: SOEREN MOURITSEN
IPC: C07K14/71
Filed: 2003-12-11
Abstract: The invention relates to novel immunogenic agents that are capable of inducing specific B-cell immunity directed against one single epitope present in a self-antigen. The immunogenic agent is a chimeric binding protein that binds specifically to a first receptor, said first receptor being one that binds a second receptor present in an antigen of an animal, wherein said chimeric binding protein comprises: (a) a B-cell epitope in the form of a binding site that specifically binds the first receptor and which competes with the second receptor for binding to the first receptor, (b) a scaffold protein structure being autologous in said mammal, and (c) at least one tolerance breaking amino acid sequence, which is heterologous in said animal and which binds to an MHC Class II molecule in said animal. In preferred embodiments, the chimeric binding protein is in the form of an anti-idiotypic antibody having a tolerance-breaking aminoacid sequence introduced. The invention further relates to methods of preparing the immunogens and methods of using the immunogens in therapy. Also, the invention relates to proteins, nucleic acid fragments, recombinantly modified host cells and virus that are useful in the practice of the methods of the invention.
Patent MX-PA05007182-A (MX)
Title: Complexes of protein crystals and ionic polymers.
Inventor: KHALAF NAZER
IPC: A61K47/42
Filed: 2003-12-31
Abstract: The present invention relates to complexes of protein crystals and ionic polymers and compositions comprising such complexes. The invention further provides methods for producing these complexes and compositions. The invention further provides methods for treatment of an individual having a disease requiring or ameliorated by sustained release of protein-based therapies.
Patent MX-PA05007749-A (MX)
Title: Single mold form fryer with enhanced product control.
Inventor: DONALD JOE TATSCH
IPC: A23L5/10
Filed: 2004-01-13
Abstract: A mold form fryer utilizing a top conveyor that transports snack pieces through a constant velocity oil stream without the need of a bottom mating mold or conveyor. Herein, the form fryer is provided with a top conveyor disposed above a fryer oil pan positioned longitudinally through the fryer. Uncooked snack pieces are provided to the fryer oil pan by a bottom entrance conveyor. Snack pieces, once in oil within the fryer, meet with molding surfaces on the top conveyor. At the exit portion of the fryer, a bottom exit conveyor receives the cooked snack pieces from the top conveyor. As no continuous bottom conveyor is utilized, the fryer oil pan may be provided with a reduced volume segment situated between the bottom entrance and exit conveyors. Additionally, the molding surfaces may be selected to produce uniformly shaped snack pieces that are either convexly or concavely shaped when viewed upon the bottom exit conveyor.
Patent MX-PA05011053-A (MX)
Title: Perform for foamed sheet product and foamed product manufactured therefrom.
Inventor: SCHRAM HENDRIK LEENDERT
IPC: C22C1/08
Filed: 2004-04-16
Abstract: Preform of a foamable laminate sheet comprising a core between two metal skin plates, said core comprising a foaming agent and a foamable metal, characterised in that the foamable metal comprises at least one foamable metal sheet and wherein the foaming agent is applied on at least one side of at least one foamable metal sheet.
Patent MX-PA05011858-A (MX)
Title: Therapeutic agents comprising an anti-angiogenic agent in combination with an src-inhibitor and their therapeutic use.
Inventor: CURWEN JON OWEN
IPC: A61K31/517
Filed: 2004-05-04
Abstract: The invention relates to the use of an anti-angiogenic agent in combination with an inhibitor of the Src family of non-receptor tyrosine kinases in the manufacture of a medicament for use in the substantially normotensive treatment in a warm-blooded mammal such as a human being of a disease state associated with angiogenesis, the Src kinase inhibitor being administered in an amount effective to counteract substantially the hypertension induced by the anti-angiogenic agent.
Patent MX-PA05013184-A (MX)
Title: Information processing device, information recording medium, information processing method, and computer program.
Inventor: UEDA KENJIRO
IPC: G09C1/00
Filed: 2005-12-06
Abstract: Scrambling of a content is improved, and false use of a content is excluded. Scramble rules different in contents are applied for content scrambling. For example, when shuffling is applied, various shuffle forms are defined as scramble rules. When an exclusive-OR operation is applied, the value used as exclusive- OR is defined as a scramble rule. When rotation is carried out, the amount of shift is defined as a scramble rule. When 32 shuffle elements are used for shuffling, 32! different shuffle forms. i. scramble rules can he defined. The value used as exclusive-OR and the amount of rotation shift can be set to various values, and many scramble rules can be set..
Patent MX-PA06000330-A (MX)
Title: System and method for query refinement.
Inventor: WATSON ERIC B
IPC: G06F17/30
Filed: 2006-01-09
Abstract: A method and system are provided for automatically enhancing initial search results produced by a search engine in response to a multi-word user query. The method may include implementing a result evaluation mechanism within the search engine for evaluating adequacy of the initial search results. The method may additionally include formulating at least one alternative query, such as a sub-query, if the initial search results are deemed inadequate by the result evaluation mechanism. The method may additionally include displaying result information including the initial search results and a listing of any formulated alternative queries.
Patent MX-PA06003897-A (MX)
Title: Method for processing a material and packing container for carrying out this method.
Inventor: BURKARD FRITZ
IPC: B65D75/58
Filed: 2004-10-07
Abstract: A method for processing a material, which is stored in a flexible packing container (1), comprises the following steps: At least one material or material mixture is fed to a first material or material mixture already located inside the packing container (1) via a filling opening (4) situated on the packing container (1); the filling opening (4) is closed (5); the materials inside the packing container are mixed; a portion of the packing container is detached, and; the material mixture is processed via the resulting opening in the packing container.
Patent MX-PA06006060-A (MX)
Title: Accessory identification algorithm for system connector.
Inventor: OHLGREN HAKAN
IPC: H04M1/72409
Filed: 2004-11-29
Abstract: Method for identifying an accessory attached to a connector of an electronic device, comprising the steps of generating a voltage pulse in said device on a pin of said connector; measuring the voltage on said pin, as affected by a load in said accessory; comparing the measured voltage with predetermined voltage criteria; and performing identification of said accessory dependent on said comparison. The method is suitable for detecting and identifying different types of accessories, for which different types of identification processes are used.
Patent MY-101586-A (MY)
Title: Method of and apparatus for sorting slide fasteners.
Inventor: YOZO OKADA
IPC: B07C5/04
Filed: 1987-07-21
Abstract: SLIDE FASTENERS (F) ARE FED LONGITUDINALLY ONE AT A TIME ALONG A PATH BY AT LEAST ONE STREAM OF AIR FLOWING ALONG THE PATH, AND THEN INTRODUCED INTO A CLEARANCE OR GATE WHICH IS NARROW ENOUGH TO PREVENT THE PASSAGE OF SLIDERS (S) SO THAT WHEN THE SLIDE FASTENERS (F) HAVE RESPECTIVE SLIDERS (S), THEY ARE STOPPED AT THE GATE WHILE WHEN THE SLIDE FASTENER S(F) HAVE NO SLIDERS (S), THEY ARE ALLOW TO PASS THROUGH THE GATE AND FURTHER ADVANCED BY THE STREAM OF AIR.THUS THE SLIDE FASTENERS (F) ARE AUTOMATICALLY SORTED OR SEPARATED INTO TWO GROUPS ACCORDING TO THE EXISTENCE OF THE SLIDERS (S). THEREAFTER, THE STREAM OF AIR IS INTERRUPTED WHEREUPON THE SLIDER FASTENERS (F) STOPPED AT THE GATE ARE ALLOWED TO FALL FROM THE PATH INTO A CONTAINER (44) DISPOSED BELOW THE GATE. THE SLIDE FASTENERS THUS FALLEN ARE DISPOSED IN THE CONTAINER (44) IN JUXTAPOSITION. (FIG. 1)
Patent MY-103098-A (MY)
Title: Improvements in the manufacture of pneumatic tyres
Inventor: ANTHONY GERALD GOODFELLOW
IPC: B29D30/20
Filed: 1988-06-10
Abstract: TYRE BUILDING APPARATUS IN WHICH A FORMER (20, 35) IS MOUNTED ON A FIRST ROTATABLE TURRET (10, 12), AND A COMPONENT CARRIER (30, 51) OF TUBULAR FORM IS MOUNTED ON A SECOND ROTATABLE TURRET ADJACENT THE FIRST TURRET. THE FORMER AND THE COMPONENT CARRIER ARE ARRANGED TO BE RELATIVELY MOVABLE AT A TURRET STATION TO ENABLE THE FORMER TO BE SURROUNDED BY THE COMPONENT CARRIER SO AS TO PERMIT TRANSFER OF A TYRE BUILDING COMPONENT BETWEEN THE FORMER AND THE CONPONENT CARRIER. (FIG)
Patent MY-103537-A (MY)
Title: Treatment of cardiac arrhythmias.
Inventor: DR MICHAEL JOHN DAVEY
IPC: A61P9/06
Filed: 1988-07-12
Abstract: 4-AMINO-6, 7-DIMETHOXY-2- [6, 7-DIMETHOXY-1, 2, 3, 4-TETRAHYDROISOQUINOL-2- Y1] QUINOLINE, IN ADDITION TO ITS ACTION AS A HYPERTENSIVE AGENT, ALSO HAS UTILITY IN THE TREATMENT OF CARDIAC ARRHYTHMIAS AT MUCH LOWER DOSE LEVELS.
Patent MY-103397-A (MY)
Title: Expansion joint for roads and bridges
Inventor: TAIZO MATSUKAMI
IPC: E01C11/10
Filed: 1988-09-20
Abstract: A COVER MEMBER SPANS AN EXPANSION JOINT GAP DEFINED BETWEEN TWO ADJACENT SPACED APART SIDE SECTIONS OF PAVEMENT LAYERS OVERLAID UPON SUBGRADES OF THE ROADS AND BRIDGES. THEN, AN ELASTOMERIC LAYER EXCELLENT IN DEFORMABILITY IS OVERLAID UPON EXPOSED UPPER SURFACES OF THE SUBGRADES AND AN UPPER SURFACE OF THE COVER MEMBER. AFTER THAT, A VISCO-ELASTIC COMPOSITE MATERIAL LAYER COMPOSED OF AGGREGATES AND BINDERS IS SO FILLED IN THE EXPANSION JOINT GAP ON SAID COVER MEMBER AS TO BE FLUSH WITH THE TRACK SURFACE OF THE ROADS AND BRIDGES. (FIG. 1)
Patent MY-104682-A (MY)
Title: Line pressure regulator.
Inventor: KENNETH JOHN DAVEY
IPC: G05D16/10
Filed: 1989-12-09
Abstract: AN IN-LINE PRESSURE REGULATOR FOR REGULATING FLUID FLOW COMPRISING A HOUSING HAVING AN INLET AND AN OUTLET, SAID HOUSING PROVIDING A FIRST CHAMBER OPEN TO THE INLET AND HAVING A FIRST PORT OPEN TO A SECOND CHAMBER, A SECOND PORT OPENING TO THE SECOND CHAMBER, THE SECOND CHAMBER HAVING A THIRD PORT OPENING TO THE OUTLET, A SUPPORT ELEMENT MOVABLY RECEIVED WITHIN THE FIRST AND SECOND CHAMBERS AND ACCOMMODATING A SET OF THREE VALVE MEMBERS WHEREIN A VALVE MEMBER IS ASSOCIATED WITH EACH PORT; THE SUPPORT ELEMENT BEING MOVABLE WITHIN THE FIRST CHAMBER TO VARY THE EXTENT OF ENGAGEMENT OF THE VALVE MEMBERS WITH THE FIRST AND SECOND PORTS, SAID SUPPORT ELEMENT BEING BIASED TO AN END POSITION AT WHICH THE FIRST AND SECOND PORTS ARE OPEN, AND THE THIRD PORT IS CLOSED, SAID SUPPORT ELEMENT SUPPORTING A PRESSURE SURFACE IN THE SECONDARY CHAMBER WHEREBY THE FORCE EXERTED BY FLUID PRESSURE IN THE SECONDARY CHAMBER ON THE SUPPORT ELEMENT COUNTERACTS THE BIASING FORCE APPLIED THERETO TO MOVE THE SUPPORT ELEMENT FROM ITS POSITION TO A REGULATING POSITION WHERE THE FIRST AND SECOND VALVES ARE MOVED PROXIMATE THE FIRST AND SECOND PORTS TO VARY THE DEGREE OF OPENING OF THE PORTS IN ACCORDANCE WITH THE FLUID PRESSURE APPLIED AT THE INLET WHEREBY THE FLUID FLOW REMAINS SUBSTANTIALLY CONSTANT OVER A RANGE OF INLET PRESSURES. (FIG. 5)
Patent MY-107171-A (MY)
Title: Photographic processing apparatus
Inventor: GLOVER EDWARD CHARLES TIMOTHY SAMUEL
IPC: G03D5/00
Filed: 1991-12-09
Abstract: IT IS KNOWN TO APPLY PROCESSING SOLUTION TO PHOTOGRAPHIC MATERIAL USING A HIGH SPEED MOVING SURFACE. HIGH SPEED ROTATING DRUMS HAVE BEEN USED TO TRANSFER PROCESSING SOLUTION FROM A RESERVOIR TO THE MATERIAL. HORIZONTAL BELTS ARE ALSO KNOWN. HOWEVER, SUCH ARRANGEMENTS REQUIRE LARGE VOLUMES OF PROCESSING SOLUTION IN ORDER TO OPERATE EFFECTIVELY. DESCRIBED HEREIN IS A PROCESSOR ( 1) COMPRISING A VERTICALLY MOUNTED HIGH SPEED BELT (10) WHICH BOTH TRANSFERS PROCESSING SOLUTION (26) FROM A RESERVOIR (20) ONTO PHOTOGRAPHIC PAPER BEING PROCESSED,AND PROVIDES AGITATION AT THE PAPER SURFACE. TWO TRANSPORT BELTS (30,32)ARE PROVIDED, ONE ON EITHER SIDE OF THE BELT (10) TO ASSIST IN THE TRANSPORT OF PAPER THROUGH THE APPRATUS. AN ARRANGEMENT ACCORDING TO THE INVENTION HAS THE ADVANTAGES THAT ONLY LOW VOLUMES OF PROCESSING SOLUTION ARE REQUIRED, GOOD SURFACE AGITATION IS PROVIDED, AND IT CAN BE FITTED INTO CONVENTIONAL PHOTOGRAPHIC PROCESSING APPARATUS. (FIGURE 1)
Patent MY-110365-A (MY)
Title: Process for the preparation of a ziegler-natta type catalyst
Inventor: BERARDI ALAIN
IPC: C08F110/02
Filed: 1993-10-26
Abstract: THE PRESENT INVENTION RELATES TO A PROCESS FOR THE PREPARATION OF A ZIEGLER - NATTA TYPE CATALYST HAVING A GRANULAR SUPPORT. THE PROCESS COMPRISES CONTACTING THE GRANULAR SUPPORT WITH (A) AN ORGANOSILICON COMPOUND, (B) A DIALKYLMAGNESIUM AND OPTIONALLY A TRIALKYLALUMINIUM COMPOUND, (C) A MONOCHLORO - ORGANIC COMPOUND, AND (D) WITH AT LEAST ONE TETRAVALENT TITANIUM COMPOUND. ACCORDING TO THE INVENTION THE ORGANOSILICON COMPOUND CAN BE A SILANE SUCH AS DIETHOXYDIMETHYLSILANE, METHYLTRIMETHOXYSILANE, METHYTRIETHOXYSILANE OR TETRAETHOXYSILANE. IT CAN ALSO BE A DISILAZANE SUCH AS HEXAMETHYLDISILAZANE.@