baber/WOPTO huggingface dataset:
Patent NZ-599824-A (NZ)
Title: Gna11 mutations in melanoma
Inventor: BASTIAN BORIS C
IPC: C12Q1/68
Filed: 2010-10-29
Abstract: Disclosed is a method of detecting a GNA11-dependent melanocytic neoplasm cell in a biological sample from a patient, wherein the sample comprises melanocytic cells, the method comprising: detecting the presence or absence of an activating sequence mutation in a GNA11 gene in the biological sample, thereby detecting the presence of the GNA11 dependent melanocytic neoplasm cell in the biological sample if the activation mutation is present. Further disclosed is a method of monitoring progression of a melanoma in a patient subject to a therapy, the method comprising detecting a change in the number of melanoma cells having an activating mutation in a GNA11 gene in a biological sample from the patient, wherein a change in the number of cells having the activating mutation is indicative of the response of the patient to the therapy. Further disclosed is the use of a GNA11 antagonist in the manufacture of a medicament for inhibiting proliferation of melanoma cells that have an activating mutation in a GNA11 gene in a patient that has a melanoma that has been determined to have an activating mutation in the GNA11 gene, the method comprising contacting a GNA11 antagonist with melanoma cells that have an activating mutation in GNA11. Further disclosed is a method of identifying a melanoma patient who is a candidate for treatment with a GNA11 inhibitor, the method comprising detecting the presence or absence of an activating mutation in a GNA11 gene in a biological sample from a melanoma present in the patient, wherein the presence of the activating mutation is indicative of a melanoma patient who is a candidate for treatment with a GNA11 inhibitor.
Patent NZ-601156-A (NZ)
Title: Electronic locking system with wireless update and cascade lock control
Inventor: BOWEN MARK
IPC: H04W12/06
Filed: 2011-01-19
Abstract: Disclosed is an interlinked cascade wireless access control system. The interlinked cascade wireless access control system includes a central wireless access system (101) and a remote wireless access system (102) which includes a plurality of remote access controllers located at access points. A wireless network (103) connects the central wireless access system (101) to the remote wireless access system (102). An individual access point contains a first remote access controller (107) representing a first level of security and at least one additional remote access controller representing a second level of security. The first remote access controller (107) must be disengaged by a first credential before the at least one additional remote access controller can be disengaged. The at least one additional remote access controller will not be disengaged unless a second credential presented to the at least one additional remote access controller belongs to an identical user as the first credential.
Patent NZ-601634-A (NZ)
Title: Location-aware emergency broadcast receiver
Inventor: ROBSON STEPHEN JAMES
IPC: H04W4/90
Filed: 2011-05-05
Abstract: 601634 Disclosed is an emergency broadcast receiver (200). The receiver (200) is comprised of an alert device (280), a tuner (240), a signal decoder (270), a location device (211) and an embedded controller (202). The tuner (240) is adapted to demodulate a baseband signal from a radio frequency signal. The signal decoder (270) is adapted to extract digital data from the demodulated baseband signal. The location device (211) is adapted to provide location data representing a location of the emergency broadcast receiver (200). The embedded controller (202) is adapted to determine periodically whether the extracted digital data represents a valid data stream and detect a trigger signal in the valid data stream. The controller (202) is also adapted to determine whether location information encoded in the detected trigger signal corresponds with the location data and activate, based on the second determination, the alert device (280).
Patent NZ-612788-A (NZ)
Title: Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
Inventor: ANDERSON ERIC
IPC: C07D487/04
Filed: 2011-12-19
Abstract: Provided are pyrazolyl and pyrimidinyl tricyclic or tetracyclic enones of general formulas (I), (Ia), (II) and (VII) where the variables are as described in the specification. Further provided are bicyclic enones of the general formula (VIII) where the variables are as described in the specification. The compounds are antiflammatory and/or antioxidant agents.
Patent NZ-625405-A (NZ)
Title: Power generation apparatus using wave energy conversion by gravity
Inventor: CHEN SHIH-HSIUNG
IPC: E02B9/08
Filed: 2014-05-22
Abstract: A power generation apparatus (1) using wave energy conversion by gravity is disclosed. The apparatus includes a sealed body (10), a rotor (20) , a gear box (30), a power generation motor (40) and a pontoon (50). The rotor, disposed in the sealed body, includes an eccentric disk (21), a plurality of rollers (22) and a rotating shaft (23) penetrating through the eccentric disk. The center of gravity of the eccentric disk is disposed with an offset to that of the sealed body. The gear box (30) is driven by the rotating shaft wich drives the generator to generate electric power. The pontoon allows the apparatus to ride the waves which cause the orientation of the apparatus to change with respect to gravity, thus causing the rotor to turn due to the center of gravity offset.
Patent NZ-625516-A (NZ)
Title: Derivatives of betulin
Inventor: HATCHER MARK ANDREW
IPC: C07J63/00
Filed: 2012-12-14
Abstract: Disclosed herein are derivatives of betulin, or a pharmaceutically acceptable salt thereof. Also disclosed are methods for the synthesis of a wide variety of derivatives of betulin and also their use in the treatment or prevention of HIV.
Patent NZ-625845-A (NZ)
Title: Emergency bearing mechanism
Inventor: PRIMUS GÜNTHER
IPC: F16C19/55
Filed: 2013-09-09
Abstract: A bearing unit for a shaft 2 carrying a pulley of a cable car, where the bearing unit includes at least one first bearing 8, at least one second bearing 9, and at least one support device. The bearing unit is configured to be arranged within a bearing frame, and an inner ring 10 of at least one first bearing 8 is connected with the shaft 2. An outer ring 11 of the first bearing 8 is connected with an inner ring 13 of a second bearing 9 and arranged in the bearing frame via this second bearing. The second bearing 9 is arranged radially outside of the first bearing 8. The inner ring 13 of the second bearing 9 in case of a defect in the first bearing 8, is supported by the shaft 2 by means of at least one support device
Patent NZ-626946-A (NZ)
Title: Methods and compositions for reducing the environmental impact of animal waste
Inventor: ANDERSON DAVID M
Filed: 2013-02-07
Abstract: Disclosed is a composition comprising alkaline phosphatase for use in increasing phosphorus digestion in an animal, wherein said alkaline phosphatase is of SEQ ID NO: 1, or an alkaline phosphatase having at least 95% sequence identity to SEQ ID NO: 1, wherein SEQ ID NO: 1 is disclosed within the specification. Also disclosed is a method for reducing the environmental impact of animal waste, comprising administering to a non-human animal an effective amount of an enzyme that reduces the amount of one or more detrimental compounds present in or released from animal waste, wherein said enzyme is alkaline phosphatase of SEQ ID NO: 1, or an alkaline phosphatase having at least 95% sequence identity to SEQ ID NO: 1.
Patent NZ-703894-A (NZ)
Title: Substituted aliphanes and metallocenes useful for treating hcv infections
Inventor: WILES JASON ALLAN
IPC: C07F17/00
Filed: 2012-05-29
Abstract: The disclosure relates to substituted aliphanes and metallocenes, of the formula shown in the abstract figure useful as antiviral agents. Certain substituted aliphanes and metallocenes disclosed herein are potent and/ or selective inhibitors of viral replication, particularly Hepatitis C virus replication. Pharmaceutical compositions/ and combinations containing one or more substituted aliphanes and metallocenes and a pharmaceutically acceptable carrier are also provided by this disclosure. Their use for treating viral infections, including Hepatitis C viral infections are provided by the disclosure.
Patent NZ-706729-A (NZ)
Title: 5-phenoxy-3h-pyrimidin-4-one derivatives and their use as hiv reverse transcriptase inhibitors
Inventor: ARRINGTON Kenneth
IPC: A61P31/18
Filed: 2013-10-07
Abstract: Compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein R1, R2, RE, L, M and Z are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
Patent NZ-712376-A (NZ)
Title: Systems, devices, and methods for processing wrapped product
Inventor: RYAN DOUGLAS TASMA
IPC: B67B7/46
Filed: 2015-09-16
Abstract: The present disclosure relates to a method of removing a wrapper from a product, and a wrapper removal system for achieving same. The method includes identifying a product type of the product, and selecting a cutting profile from a plurality of cutting profiles based on the product type. A manipulator is controlled to move a cutting device in accordance with the selected cutting profile to cut the wrapper.
Patent NZ-713226-A (NZ)
Title: Vertical axis water/wind turbine motor using flight feather opening/closing wing system
Inventor: TAMATSU YOSHIJI
IPC: F03D3/06
Filed: 2014-05-24
Abstract: [Problem] A combined water/wind turbine provided with a drag type in order to enhance the startability of a lift type has a problem that resistance to the rotation force of the combined water/wind turbine is produced when the limit of the high-speed rotation capability of the drag type is reached or exceeded, and causes performance to become lower than the capability during high-speed rotation of the lift type alone. [Solution] In order to enhance the startability of a vertical axis combined water/wind turbine motor composed of a drag type and a lift type, starting performance is improved by releasing convex surface resistance produced by a drag-type blade going against a fluid, and increasing rotation torque by reduction in resistance, during rotation at high speed higher than or equal to the speed of the fluid, which is the characteristic of a lift-type blade, all wing surfaces of the drag type are naturally brought into an open state by the lift-type blade rotation speed to thereby maintain lift-type high-speed rotation efficiency performance by reducing resistance at the center of the vertical axis combined water/wind turbine motor in a wide range of fluid speed area, and danger when the fluid speed increases is avoided by producing a fully open state by rolling in flight feathers of a drag-type wing surface configuration, by decreasing the entire volume by folding wing surfaces to the rotation shaft side, or by decreasing the entire structure and reducing resistance by eliminating passive surfaces by decreasing the wing area by drawing flight feathers of the wing surface toward the rotation center.
Patent NZ-715280-A (NZ)
Title: Rna-guided transcriptional regulation
Inventor: CHURCH GEORGE M
IPC: C07H21/02
Filed: 2014-06-04
Abstract: Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more guide RNAs complementary to DNA, wherein the one or more guide RNAs comprise a tracrRNA and crRNA and wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more guide RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more guide RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more guide RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid.
Patent NZ-717409-A (NZ)
Title: Synergistic liposomal formulation for the treatment of cancer
Inventor: ALI NAHID
IPC: A61K9/127
Filed: 2014-09-18
Abstract: The present disclosure relates to the synergistic liposomal formulation comprising, phophatidylcholine, stearylamine and anticancer drugs for the treatment of cancer. The PC:SA cationic liposome encapsulated camptothecin (CPT) and doxorubicin (DOX) formulations show enhanced synergistic anti-cancer effect and provide improved therapeutic index as compared to either the liposome or drug alone. The present disclosure also relates to the use of Cationic liposomal preparation of phosphatidylcholine:stearylamine (PC:SA) showing anticancer effect. The SA-bearing liposome and drug entrapped in the liposome are effective against cancer both in vitro and in vivo, without causing any adverse effect on host.
Patent NZ-718744-A (NZ)
Title: Salt and crystal forms of plk-4 inhibitor
Inventor: PAULS HEINZ W
IPC: A61P35/00
Filed: 2014-10-17
Abstract: Fumarate and maleate salts of compound (I), a PLK-4 inhibitor, are disclosed wherein the molar ratio is 1:1. These salts form crystalline solids which are suitable for pharmaceutical development and preparing pharmaceutical compositions. These fumarate and maleate crystalline forms have good oral bioavailability. Particular single crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are disclosed along with the use of the fumarate and maleate salts of compound (I) for the treatment of cancers.
Patent NZ-726326-A (NZ)
Title: Wheel hub arrangement
Inventor: WEIGAND WERNER
IPC: F16C33/80
Filed: 2015-03-31
Abstract: The present invention relates to a wheel cover and to a wheel hub arrangement comprising a wheel cover. The wheel cover can be fixed in a recess in the hub in such a way that the wheel cover delimits an outer region with respect to an inner region of the hub. A gap is formed between the hub and the wheel cover. A seal element is arranged in the gap. The seal element has a main body and a sealing lip. The sealing lip projects from the main body and faces the outer region. The wheel cover provides improved protection of a wheel hub from liquids or dirt particles impinging at high speed.
Patent NZ-737216-A (NZ)
Title: Emulsifiable concentrate comprising a phenoxy-alkanoic acid herbicide
Inventor: PANAYI ARISTOS
IPC: A01N25/30
Filed: 2016-05-06
Abstract: The invention relates to emulsifiable concentrate compositions of phenoxyalkanoic acid herbicides in the acid form. The acid form while providing advantages in efficacy is water insoluble and difficult to formulate as a stable emulsifiable concentrate. While attempts have been made to formulate phenoxyalkanoic acid herbicides as emulsifiable concentrates in amide solvents the compositions show a propensity for forming crystalline deposits on storage or poor emulsion stability on dilution. The invention provides the formulation of phenoxyalkanoic acid herbicides as the acid in an emulsifiable concentrate containing an amide solvent and a selected amine or mixture.
Patent NZ-741405-A (NZ)
Title: A bag-in-box system for use in dispensing a pumpable product
Inventor: KENNEDY THOMAS
IPC: B65D77/06
Filed: 2014-02-10
Abstract: A bag-in-box system for use in dispensing a pumpable product includes a carton, a flexible thermoplastic pouch disposed in the carton, a spout joined to the pouch, a spout closure, and a pumpable product disposed in the pouch, the flexible thermoplastic pouch including an outer wall including a coextruded film having a polyethylene layer, a tie layer, and a polyamide layer, and a discrete inner wall including an ethylene polymer or copolymer, or a composition like that of the outer wall, the outer wall sealed to the inner wall at the perimeter of the pouch. Optionally, a discrete intermediate wall can be disposed between the outer wall and inner discrete wall of the pouch. The system can further include a pump operatively connected to the pouch and carton to dispense the pumpable product from the pouch. The system provides an alternative to current systems for dispensing pumpable products that often suffer from one of two problems: the occurrence of pin-holes due to flex-cracking in metallized pouch materials, and the use of coextruded multilayer barrier films in pouch construction that lack sufficient toughness in terms of burst strength.
Patent NZ-743895-A (NZ)
Title: Use of treating elements to facilitate flow in vessels
Inventor: HAM PETER
IPC: F15D1/00
Filed: 2017-02-10
Abstract: A method for facilitating the distribution of the flow of one or more streams within a bed vessel is provided. In the prior art, many bed vessels face challenges associated with sustaining effective and efficient utilization of bed vessel internals including effective and efficient stream flow distribution across and throughout the beds of solid processing material elements installed in the bed vessels. Inadequate stream flow distribution leads to coalescence of small stream rivulets into larger streams resulting in stream flow channeling which can result in bypassing portions of the bed vessel processing internals. In the present invention, disposed within the bed vessel are internal materials and structures including multiple operating zones. One type of operating zone can be a processing zone composed of one or more beds of solid processing material. Another type of operating zone can be a treating zone. Treating zones can facilitate the distribution of the one or more streams fed to processing zones. The distribution can facilitate contact between the feed streams and the processing materials contained in the processing zones, thereby attempting to address one or more problems mentioned above.
Patent NZ-748704-A (NZ)
Title: Fishing rod ruler
Inventor: SIMIC MICHELLE
IPC: A01K87/00
Filed: 2017-04-26
Abstract: Disclosed is an incorporated ruler on a fishing rod by a temporary application of markings added by a tapering elongated flexible substrate and to finish coated by a layer of resin or lacquer, mitigates the effect of delamination because of flexion and stress as in the case of a sticker. A fishing rod with a tapering incorporated ruler, the tapering incorporated ruler having length markings provided by a substrate having an elongate flexible body with a number of length markings to provide markings onto the fishing rod, wherein the elongate flexible body is only temporarily applied to the fishing rod whilst the markings are provided onto the fishing rod, and the tapering incorporated ruler is provided beneath at least one finishing layer of resin or lacquer used to finish the fishing rod over at least the tapering incorporated ruler.
Patent NZ-753015-A (NZ)
Title: Battery pack, electrical device using battery pack, and electrical device system
Inventor: HANAWA HIROYUKI
IPC: H02J7/36
Filed: 2017-10-27
Abstract: In an upper cell unit 2146 and a lower cell unit 2147 comprising five battery cells, positive electrode terminals (2162, 2172) are set apart and aligned vertically, and negative electrode terminals (2167, 2177) are set apart and aligned vertically. When an electrical device body is rated at 36V, device-side terminals are in contact only at the upper terminals 2162, 2167, and short circuiting of the lower terminals 2172, 2177 is effected using a short bar 2059. When the electrical device body is rated at 18V, the upper and lower terminals (2162 and 2172, 2167 and 2177) are simultaneously made to contact the device-side terminals, and the upper cell unit 2146 and the lower cell unit 2147 assume a parallel connected state. Thus, it is possible to automatically switch the output voltage when a battery pack is mounted according to the difference in terminal shape on the electrical device body side.
Patent NZ-760459-A (NZ)
Title: Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy
Inventor: CHANDRARATNA ROSHANTHA A
IPC: A61K39/395
Filed: 2018-07-12
Abstract: Disclosed herein are methods for treating cancer comprising administering CAR-modified immune cells and at least one Retinoic Acid Receptor (RAR active agent), wherein the RAR active agent is the RARy agonist of formula (IV).
Patent NZ-763020-A (NZ)
Title: Illumination system for light projection
Inventor: SYVOKIN VIKTOR
IPC: G02B11/04
Filed: 2017-12-18
Abstract: A system for delivering light from a light source to a digital micro-mirror device. The system includes one or more lens groups. At least one lens of the system is laterally displaced, so that its optical axis is not centered on the chief ray of the system. In some systems, the light delivery system may be designed to generate an oversized illumination patch that overfills the digital micro-mirror device considerably more than required by just manufacturing and assembly tolerances, so that the uniformity of illumination over the digital micro-mirror device is acceptable in spite of the imperfect rectangularity of the illumination patch or blurring at its edges, the regions affected by these imperfections falling off of the edges of the digital micro-mirror device. To solve this issue the system includes one or more lens groups. At least one lens within a first lens group is laterally displaced, so that its optical axis is not centered on the chief ray of the system.
Patent NZ-766902-A (NZ)
Title: Flame resistant fabrics for protection against molten metal splash
Inventor: ADAMS DOMINIQUE JANAY
IPC: A41D31/08
Filed: 2019-02-08
Abstract: Embodiments of the present invention relate to flame resistant fabrics that provide protection against molten metal splash but that have improved comfort at a lower cost by predominantly locating the protective molten metal shedding fibers on the front face of the fabric. Concentrating the protective fibers predominantly on the front face of the fabric still provides good protection against molten metal adherence and allows for more comfortable (and less expensive) fibers to be used on the back face of the fabric positioned next to the wearer. In this way, overall protection of the fabric is maintained while improving comfort. Embodiments of such fabrics may also achieve NFPA 70E PPE Category 2 protection (>8 cal/cm2arc rating whether ATPV or EBT).
Patent PT-101841-A (PT)
Title: Electronic sphincter
IPC: A61F2/48
Filed: 1996-03-01
Abstract: This is a small electronic apparatus which is inserted in the urinary sphincter and which remains there until it is removed. The aim of this apparatus is to replace the urinary sphincter when this no longer functions properly, which is the case of incontinence patients, of deformed sphincters and of neurogenic bladders. The apparatus has a cylindrical format which is similar to that of a normal (non-curved) "algália" point. The apparatus is hollow inside, as if it were a small tube, and in the middle of this interior it has a valve connected to an electronic mechanism (motor) which makes it possible to open and close the valve by remote control. The valve also has at its outer ends a special format or an air sack (consistent with the model), which allows the apparatus to be installed in the urinary sphincter and for it not to come out. The apparatus opens and closes on an indication given via the remote control, allowing the person to empty the bladder. <IMAGE>