baber/WOPTO huggingface dataset:
Patent AU-2004212067-B2 (AU)
Title: [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride polymorph
Inventor: BUBENDORF ANDRE GERARD
IPC: C07D239/94
Filed: 2004-02-11
Granted: 2009-03-19
Abstract: The invention is concerned with a novel polymorph of [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride. This polymorph exhibits superior properties compared to the previously known forms of [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride. The [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride is an inhibitor of tyrosine kinase enzymes, and are useful in the treatment of cancer. Also disclosed are methods of making and using the novel polymorph, as well as pharmaceutical compositions containing the novel polymorph.
Patent AU-2005222782-B2 (AU)
Title: Methods of refolding mammalian glycosyltransferases
Inventor: SARIBAS SAMI
IPC: C12N15/00
Filed: 2005-02-04
Granted: 2010-06-17
Abstract: The present invention provides methods of refolding mammalian glycosyltransferases that have been produced in bacterial cells, including glycosyltransferase mutants that have enhanced ability to be refolded, and methods to use such refolded glycosyltransferases. The invention also provides methods of refolding more than one glycosyltransferase in a single vessel, methods to use such refolded glycosyltransferases, and reaction mixtures comprising the refolded glycosyltransferases.
Patent AU-2005235315-B2 (AU)
Title: Removable vena cava filter with anchoring feature for reduced trauma
Inventor: MOLGAARD-NIELSEN ARNE
IPC: A61F2/01
Filed: 2005-04-18
Granted: 2010-09-09
Abstract: The present invention involves a removable filter for capturing thrombi in a blood vessel. The filter comprises a plurality of struts having first ends attached together along a longitudinal axis of the filter. Each strut has a body member extending from the first end along the longitudinal axis to an anchoring hook defining a strut axis. Each strut is configured to move along a strut path relative to the longitudinal axis between an expanded state for engaging with the blood vessel and a collapsed state for filter delivery or retrieval. Each anchoring hook has an angle of up to about 90 degrees relative to the strut axis.
Patent AU-2005315503-B2 (AU)
Title: Stabilised 99mTc compositions
Inventor: MARTINUSSEN GRETHE KARIN
IPC: A61K103/10
Filed: 2005-10-14
Granted: 2011-06-02
Abstract: The present invention relates to stabilised 99mTc radiopharmaceutical compositions of the ligand tetrofosmin, which include an ascorbic acid or ascorbate radioprotectant, in the absence of an antimicrobial preservative. The invention also provides lyophilised kits suitable for the bulk preparation of multiple unit patient doses of 99mTc-tetrofosmin metal complexes. Also disclosed are unit doses of 99mTc-tetrofosmin, together with processes for preparing such unit doses from the lyophilised bulk vial.
Patent AU-2006275105-B2 (AU)
Title: Shin guard
Inventor: SCHEFFER HARALD
IPC: A41D13/015
Filed: 2006-07-17
Granted: 2012-07-19
Abstract: The invention relates to a shin guard, in particular for footballers, having a stiff shield element (3) arranged in front of the shin, and having means of fastening the shield element (3) on the lower leg (1). According to the invention, the fastening means have a strapping device (2) running around the lower leg (1), and the shield element (3) is connected to the strapping device (2) over much of its inner surface (18), which is directed towards the shin.
Patent AU-2006275412-B2 (AU)
Title: Cartons with dispensing features
Inventor: BRADFORD PAUL
IPC: B65D71/36
Filed: 2006-08-01
Granted: 2010-08-12
Abstract: Cartons have dispensers that allow ease of access to articles accommodated within the cartons. A carton has a back panel, a top panel, a front panel, a bottom panel, a first end panel, a second end panel, and a dispenser/stand pattern disposed in the top panel and the front panel and defining a dispenser/stand. The carton is capable of being placed in a dispensing configuration in which the dispenser/stand provides a dispenser opening and supports the carton in an inclined position. The dispenser/stand is connected to the front panel when the dispenser/stand supports the carton in an inclined position.
Patent AU-2006306521-B2 (AU)
Title: The induction of indoleamine 2,3-dioxygenase in dendritic cells by TLR ligands and uses thereof
Inventor: DAVID MUNN
IPC: A61K31/381
Filed: 2006-10-20
Granted: 2011-12-22
Abstract: The induction of indoleamine 2,3-dioxygenase (IDO) in an IDO-competent subset of dendritic cells by TLR ligands, including TLR9 ligands, and various uses thereof are presented.
Patent AU-2006325754-B2 (AU)
Title: Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIa inhibitors
Inventor: SMITH II LEON M
IPC: C07D471/18
Filed: 2006-12-13
Granted: 2012-04-12
Abstract: The present invention provides compounds of Formula (I): Formula (I) or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L, M and R are as defined herein. The compounds of Formula (I) are selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
Patent AU-2006328208-B2 (AU)
Title: Personal seated resting support
Inventor: BLACKWOOD HAMILTON GORDON
IPC: A47C16/00
Filed: 2006-12-19
Granted: 2011-10-06
Abstract: The present invention relates to a resting support (10) for supporting portions of a resting person (1) in a forwards leaning seated position, and to a method of using such a support. The resting support (10) comprises at least one supporting section (9, 35) including a main supporting section (9) for supporting directly said seated resting person's upper torso (3) and head (9), and means for positioning and supporting said section(s) (9, 35) above the lap (6) of said person (1) including at least two legs (21 , 22) that extend downwardly from one or more of said sections (9, 35), wherein: - the main supporting section (9) in use extends at an upwards sloping angle (27) from a lower region (28) for supporting said person's upper torso (3) towards an upper region for supporting said person's head (2); - said at least two legs include at least one rear leg (22) proximate said lower region (28) and at least one forwards leg (21) proximate said upper region, the rear leg(s) (22) being adapted for engaging with a seat (25) on which said person (1) is seated and the front leg(s) (21) being adapted for engaging with a floor (24) beneath said seat (25), said at least two legs (21 , 22) being movable relative to said sections (9, 35) to enable the section(s) to fold flat with said legs when not in use.
Patent AU-2006336816-B2 (AU)
Title: Strip of hot rolled micro-alloyed steel for obtaining finished pieces by cold pressing and shearing
Inventor: GIOVANNI ARVEDI
IPC: C22C38/00
Filed: 2006-01-26
Granted: 2011-09-15
Abstract: A micro-alloyed low carbon steel strip is obtained by hot rolling at temperature of the pre-strip never lower than 900°C and shows such metallurgical and geometrical features, as well as relating to planarity and deformability, to render the same suitable to obtain structures of low weight and good mechanical resistance, thus being able for use in replacement of cold rolled strips for the production of finished stamped or cut pieces. Said steel strip, having thickness > 0.7 mm, has a ratio yield load/breaking load > 70%, a fine grain structure better than grade 10 of ASTM E 112 standard in a percentage higher than 90% of the whole structure and a ratio between breaking limit under strain and yield point σFp/RPo.2> 90%.
Patent AU-2007263391-B2 (AU)
Title: 3 -amino-imidazo[1, 2-A]pyridine derivatives as SGLT inhibitors
Inventor: CEZANNE BERTRAM
IPC: A61K31/437
Filed: 2007-05-25
Granted: 2012-05-17
Abstract: Disclosed are novel compounds of formula (I), wherein X, Y, R, R', R, R, R, R, R, R, R, R, R, R, and n have the meanings indicated in claim 1. Said novel compounds are suitable as antidiabetics.
Patent AU-2007267843-B2 (AU)
Title: Method for treating proliferative disorders associated with protooncogene products
Inventor: KEVIN FOLEY
IPC: A61K31/4188
Filed: 2007-05-25
Granted: 2011-10-13
Abstract: The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating Bcr-Abl, FLT-3, EGFR, c-Kit, B-raf, and NPM-ALK associated cancers, in a subject in need thereof.
Patent AU-2007281018-B2 (AU)
Title: Corneal and epithelial remodelling
Inventor: CONRAD FABIAN
IPC: A61B3/10
Filed: 2007-07-31
Granted: 2013-01-24
Abstract: This invention relates to methods of shaping the anterior surface of the eye for controlling the progression of refractive error of the eye, in particular, myopia. The method employs the fitting of orthokeratology lenses having a precisely shaped posterior surface adapted to accurately shape the peripheral region of the eye. The method includes the steps of assessing central and peripheral refractive error parameters for the eye, determining the optimal anterior surface profile for the eye, including at both the optical centre of the cornea and at a selected optical periphery of the cornea, which would result in a desired refractive correction to achieve good vision for the eye and the desired peripheral refraction (curvature of field) for the eye for controlling progression of myopia. Accurate measurement of the shape of the pre-treated eye is important, thereby enabling a corresponding lens profile to be designed or selected so that the treatment process achieves a post-treatment peripheral profile which optimally focuses peripheral rays anteriorly of the retina, thereby controlling the progression of myopia. The invention extends to a lens manufactured so as to optimally treat the peripheral region of the eye.
Patent AU-2007290935-B2 (AU)
Title: Container for holding a stack of premoistened wipes
Inventor: MCDONALD DUANE LYLE
IPC: B65D83/08
Filed: 2007-07-13
Granted: 2013-03-21
Abstract: A container particularly well suited to hold premoistened wipes is described. The container can be formed primarily from a flat polymeric sheet, with a top including a lid for giving access to the interior of the container. In one embodiment, for instance, the container can be formed and loaded with a stack of wipes all in a single process. Further, the flat polymeric sheet used to form the container can be printed with various graphics during formation of the container so as to apply any suitable graphics to the container. Through the process of the present disclosure, containers can be formed having a sleek and compact design.
Patent AU-2007298506-B2 (AU)
Title: RNA interference mediated inhibition of Aurorakinase B and its combinations as anticancer therapy
Inventor: MURALI KRISHNA ADDEPALLI
IPC: A61K31/7088
Filed: 2007-06-21
Granted: 2012-04-05
Abstract: This invention relates to the use of short nucleic acid molecules that modulate Aurora-B kinase (AurkB) expression. The invention includes compounds, compositions and methods useful for the modulation of expression and activity of genes involved in the AurkB pathway. In one embodiment, the present invention provides short nucleic acid molecules, such as siRNA, which can be used in treating, preventing, or inhibiting cancer, and any other proliferative disease, trait or condition, which respond to a reduction in AurkB expression in a cell or tissue. Such short nucleic acid molecules can be used alone or in combination with other treatments or therapies, including short nucleic acid molecules that modulate expression of EGFR.
Patent AU-2007317846-B2 (AU)
Title: Combined air pulsator and movable pedestal
Inventor: LARSON MICHAEL W
IPC: A61H9/00
Filed: 2007-11-07
Granted: 2013-04-18
Abstract: A portable human body pulsating apparatus (10) has an air pulse generator (1 1) mounted on a pedestal (29) having wheels (38) to facilitate movement of the apparatus (10) on a surface. The pedestal (29) has an upright piston and cylinder assembly (31) operable to adjust the elevation of the air pulse generator (11).
Patent AU-2007334348-B2 (AU)
Title: Chromogenic medium for the detection and identification of vancomycin resistant enterococci and method therefor
Inventor: KIRCHER SUSAN
IPC: G01N33/569
Filed: 2007-12-18
Granted: 2013-05-30
Abstract: A microbe-specific medium, containing specific chromogenic substrates, for the detection of vancomycin- resistant enterococci in a biological sample, whereby both the detection and identification of vancomycin-resistant enterococci at the species level is achieved utilizing one sample and one test.
Patent AU-2007341274-B2 (AU)
Title: Use of 10-[(3R)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine for the preparation of a drug having a selective inhibition of muscarinic M1, M2 and M3 receptors
Inventor: PRZYBYLSKI CHRISTOPHE
IPC: A61K31/5415
Filed: 2007-12-26
Granted: 2012-09-20
Abstract: The present invention relates to the use of 10-[(3R)-1- azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine as well as its pharmaceutically acceptable salts for the preparation of a drug having the particularity of treating or preventing urinary incontinence, by local and/or oral route.
Patent AU-2007351374-B2 (AU)
Title: Mesh pouches for implantable medical devices
Inventor: TIMOTHY SHARI
IPC: A61B19/00
Filed: 2007-11-06
Granted: 2012-11-08
Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The pouches of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use, and, optionally, include one or more drugs in the polymer matrix of the coating to provide prophylactic effects and/or alleviate side effects or complications associated with the surgery or implantation of the CRM or other implantable medical device.
Patent AU-2008200674-B2 (AU)
Title: Open Showcase with Light Emitting Diodes
Inventor: SHIBUSAWA SAKUMI
IPC: A47F3/00
Filed: 2008-02-13
Granted: 2012-12-13
Abstract: OPEN SHOWCASE There is disclosed an open showcase provided with a light device capable of simplifying a maintenance operation and improving a cooling efficiency in a display 5 chamber. In the open showcase (1), a display chamber (11) is formed in an insulating wall (2) to display commodities in the display chamber (11) while cooling the commodities, the showcase includes a reflective plate (45) which extends externally from a front surface opening (12) of the display chamber (11), and LED lights (40) attached to the reflective plate (45), and the inside of the display chamber (11) is illuminated with 1o light emitted from the LED lights (40). 40 45 114 13 832B 16 32 - 2 35--- 31 1934--'
Patent AU-2008249440-B2 (AU)
Title: Leakproof container
Inventor: DALEY TODD
IPC: B65D25/34
Filed: 2008-11-27
Granted: 2016-02-18
Abstract: \OPMThiNP$CM\30470 AU ampleAkpma fls .d IF2e0S A carton formed from a blank 1 of foldable material such as corrugated board, the carton comprising a base 2, side walls 3, 4 and end walls 5, 6 connected to the base along fold lines, leakproof gusset means 7 to 10 connecting the side walls and end walls along 5 fold lines, each end wall or side wall having a first flap 19, 20 joined to the end wall or side wall along at least one fold line, a second flap 23 to 26 joined to the first flap and to the adjacent leakproof gusset means along fold lines 28 of such a configuration that folding of the gusset means towards the end wall or side wall causes folding of the first flap about its fold line(s) to facilitate completion of folding of the flaps and gusset means with respect 10 to the end wall or side wall. 'ER9 l n n u w Lr \ --- -- - ---- ---- cc tJD
Patent AU-2008286678-B2 (AU)
Title: Fin plug assembly and method of installation
Inventor: DURANTE MICHAEL
IPC: B63B35/79
Filed: 2008-08-05
Granted: 2014-08-28
Abstract: A fin plug assembly, for a surfcraft, including: a fin plug including a substantially flat upper portion having an external perimeter and top and bottom surfaces, at least one fin cavity for receiving a base element of a surfcraft fin extending inwardly from at least one opening in the top surface, a base portion extending from said bottom surface and surrounding said at least one fin cavity; and a high density foam body having an upper surface, a lower surface, a fin plug cavity extending from said upper surface to said lower surface, and a continuous side wall extending about said foam body and between said upper surface and said lower surface; wherein the base portion of the fin plug is located within said fin plug cavity and said fin plug is firmly affixed to said high density foam body.
Patent AU-2008286769-B2 (AU)
Title: Flapper gas lift valve
Inventor: MESSICK TYSON
IPC: E21B43/00
Filed: 2008-08-15
Granted: 2014-12-11
Abstract: A gas lift valve has a flow restrictor, a valve part on one side of the flow restrictor, a flow deflector and a tubular member on another side of the flow restrictor, and a flapper valve on the side of the flow restrictor where the tubular member is located, the flapper valve being adjacent to the tubular member. When fluid flows into the gas lift valve at sufficient pressure, the valve part opens, the fluid flows through the flow restrictor and acts on the flow diverter thereby moving the tubular member and opening the flapper valve. The tubular member extends though the opening the flapper valve covered.
Patent AU-2008296170-B2 (AU)
Title: Photostabilizing silicone fluids
Inventor: PAVLOVIC ANNA
IPC: C08L83/08
Filed: 2008-09-05
Granted: 2013-08-29
Abstract: A silicone fluid comprising a chromophore-substituted polyorganosiloxane having a formula (2) wherein x is an integer in the range of 60 to 2000, \ is an integer in the range of 5 to 100, a ratio \ y is in a range of about 10 1 to about 20 1, and X is a photostabilizing chromophore
Patent AU-2008314722-B2 (AU)
Title: Curable liquids and inks for toys and food packaging applications
Inventor: CLAES ROLAND
IPC: C09D11/00
Filed: 2008-10-16
Granted: 2011-06-09
Abstract: A free radical curable liquid for inkjet printing of food packaging materials comprising no initiator or otherwise one or more initiators selected from the group consisting of non-polymeric di- or multifunctional initiators, oligomeric initiators, polymeric initiators and polymerizable initiators; 
wherein the polymerizable composition of said liquid consists essentially of: 
a) 25 - 100 wt% of one or more polymerizable compounds A having at least one acrylate group G1 and at least one second ethylenically unsaturated polymerizable functional group G2 different from the group G1; 
b) 0 - 55 wt% of one or more polymerizable compounds B selected from the group consisting of monofunctional acrylates and difunctional acrylates; and 
c) 0 - 55 wt% of one or more polymerizable compounds C selected from the group consisting of trifunctional acrylates, tetrafunctional acrylates, pentafunctional acrylates and hexafunctional acrylates, with the proviso that if the weight percentage of compounds B > 24 wt%, then the weight percentage of compounds C > 1 wt%;  
and wherein all weight percentages of A, B and C are based upon the total weight of the polymerizable composition; 
with the proviso that at least one polymerizable compound B or C is present in the polymerizable composition if the free radical curable liquid contains no initiator; 
wherein the polymerizable compound A has a copolymerization ratio of   
with r 1  and r 2  representing the copolymerization parameters of methyl-G1 respectively methyl-G2 determined according to the method of Kelen-Tudos.
Patent AU-2008317354-B2 (AU)
Title: Methods and compositions for targeted integration
Inventor: HOLMES MICHAEL C
IPC: C12N15/867
Filed: 2008-10-23
Granted: 2014-04-10
Abstract: Disclosed herein are methods and compositions for targeted integration of one or more copies of a sequence of interest using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain and integrase defective lentiviral donor constructs.
Patent AU-2008337976-B2 (AU)
Title: Nontoxic polysiloxane material for producing biologically resorbable and/or bioactive articles containing polysiloxane material, its production and use
Inventor: EHRIG ANJA
IPC: C03B7/00
Filed: 2008-12-09
Granted: 2014-05-08
Abstract: The invention relates to a nontoxic polysiloxane material and matured polysiloxane material which has been formed using one or more different polysiloxane materials. Such a matured polysiloxane material can according to the invention be, for example, spun to produce biologically resorbable and/or bioactive fibres and then be processed further to form nonwovens.
Patent AU-2008343813-B2 (AU)
Title: Inhibitors of PI3 kinase
Inventor: LIU LONGBIN
IPC: C07D487/04
Filed: 2008-12-18
Granted: 2012-04-12
Abstract: The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof, that inhibit phosphoinositide 3-kinase; Formula (I) methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds.
Patent AU-2009204802-B2 (AU)
Title: Process to provide a particulate solid material to a pressurised reactor
Inventor: PIETER DER PLOEG GOVERT GERARDUS VAN
IPC: C10J1/207
Filed: 2009-01-15
Granted: 2011-11-24
Abstract: The invention is directed to a process to provide a particulate solid carbonaceous material to a pressurised gasification reactor by performing the following steps, (a)transporting the solid material from a first lower pressure zone to a higher pressure zone using a bulk materials pump comprising a housing having a flow path for the solid feedstock between an inlet fluidly connected to the first lower pressure zone and an outlet of said housing fluidly connected to the higher pressure zone, wherein said flow path in said housing is further defined by a space between two rotatable drive disks spaced from each other and wherein a materials scraper is present between said drive disks at the outlet to route the cake of solid materials as being transported between said drive disks to a transport conduit, which transport conduit fluidly connects the outlet of said housing and a burner as present in the gasification reactor, and (b)injecting a gaseous stream into the cake of solid materials at the point where the cake of solid materials is discharged from the housing and enters the transport conduit, and (c)transporting the solid material and the gaseous stream in a transport conduit to the burner.
Patent AU-2009209155-B2 (AU)
Title: Ophthalmic lenses for correction of aberration and processes for production of the lenses
Inventor: COLLINS MICHAEL
IPC: G02C7/04
Filed: 2009-01-29
Granted: 2013-11-14
Abstract: The invention provides a lens useful in correction of low and high order ocular wavefront aberrations order aberrations, and methods for designing and producing the lens, in which excessive variations in lens thickness are minimized.