baber/WOPTO huggingface dataset:
Patent DK-2046787-T3 (DK)
Inventor: ALLEN DAVID GEORGE
IPC: A61K31/437
Filed: 2007-07-31
Granted: 2011-07-18
Abstract: The invention provides N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo [3,4-b]pyridin-5-yl]methyl}-4-({8-[(2-hydroxyethyl) (methyl)amino]octanoyl}amino)benzamide, whose formula is or a salt thereof, such as the monohydrochloride salt thereof. The invention also provides the use of the compound or salt as inhibitors of phosphodiesterase type IV (PDE4) and/or for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, or rhinitis (e.g. allergic and/or non-allergic rhinitis).
Patent DK-2084529-T3 (DK)
Inventor: HIDALGO ISMAEL J
IPC: C12N15/113
Filed: 2007-11-09
Granted: 2011-02-07
Abstract: Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided.
Patent DK-2068918-T3 (DK)
Inventor: REED STEVEN G
IPC: A61K39/39
Filed: 2007-09-26
Granted: 2012-07-30
Abstract: Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogenous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.
Patent DK-2080454-T3 (DK)
Inventor: OZANNE MATTHIEU
IPC: A47J31/36
Filed: 2008-01-18
Granted: 2010-11-22
Abstract: A beverage machine comprising a device (10) designed for brewing a beverage on the basis of ingredients contained in a capsule (2), the beverage device (10) comprising means (63, 51) for retaining the capsule (2) in a defined position, first opening means (38) for opening a hot water inlet into the capsule while the capsule is retained in the defined position, second opening means (37) for opening a beverage outlet (41 b) from the capsule while the capsule is retained in the defined position, is  characterized in that  the first opening means (38) comprises at least one opening (114, 118) which is directed downwards to the lowermost part of the capsule while the capsule is retained in the defined position.
Patent DK-2299878-T3 (DK)
Inventor: BAMBI PIERO
IPC: A47J31/00
Filed: 2008-04-30
Granted: 2012-03-05
Abstract: An espresso coffee machine comprises a boiler and a pump for feeding hot water under pressure to one or more brew groups (1), each of which comprises a receptacle (24) for infusing a predetermined dose of ground coffee, a hot water feed pipe (38) and an outlet pipe (40). Manual operating means (30, 50) are provided at the inlet of each brew group for selectively putting the coffee powder receptacle (24) in communication with the water feed pipe (38), with the outlet pipe 40 or with both the pipes in order to preinfuse the coffee powder.
Patent DK-2133100-T3 (DK)
Inventor: SKEIKY YASIR
IPC: C07K19/00
Filed: 2001-06-20
Granted: 2012-01-23
Abstract: The present invention relates to compositions and fusion proteins containing at least two  Mycobacterium  sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.
Patent DK-0386694-T3 (DK)
Inventor: HOLZKNECHT WILFRIED
IPC: A23K1/00
Filed: 1990-03-06
Granted: 1993-08-02
Abstract: Foods which are not suitable, or are no longer suitable, for consumption have to be separated from their packaging in order to be usable as animal feed. 
<??>This is achieved by subjecting the foods with the packaging to preliminary comminution by crushing, and shaping the comminuted product to an extrudate, slicing the extrudate and subsequently separating the foods from the remains of the packaging by pressing the food through a sieve, the apparatus for carrying out the process being provided with a double screw (12) for comminution, a rotating multiple bladed knife (2) and a sieve press (3). 
<??>The area of application is the food industry. 
<IMAGE>
Patent DK-0426309-T3 (DK)
Inventor: GILL MICHAEL JOHN
IPC: G01F1/66
Filed: 1990-10-08
Granted: 1995-12-27
Abstract: A measurement system for measuring the time for a signal to pass between two transducers TDR1,2 to allow fluid speed or flow to be determined in a gas meter for example. Each transducer can transmit or receive signals. The system is controlled by a microcontroller 31 and a signal with a phase change acts as a marker which is transmitted from transmitter 21 via matching stage 22,23 from one transducer and is received by the other. On receipt via the matching stage and amplifier 24 it is sampled by capacitor array 25 and detected in detector 29. Amplitude information from array 25 is made available to the microcontroller to compute time of signal travel and hence flow rates.
Patent DK-0409685-T3 (DK)
Inventor: LAFORET JEAN
IPC: F24C15/32
Filed: 1990-06-29
Granted: 1993-02-22
Abstract: A furnace operating with steam and/or gas for cooking foodstuffs and comprising an enclosure containing on the one hand a gas burner connected to a system for supplying a mixture of gas and of combustion air under pressure which is mounted in the upper portion of the enclosure in an inverted downwards directed position and on the other hand a turbine for stirring the heated atmosphere within the enclosure.
Patent DK-0434581-T3 (DK)
Inventor: BART GILLES
IPC: G01N35/00
Filed: 1990-12-18
Granted: 1995-07-17
Abstract: Dissolution cell for solids which comprises: 
 
  - a receptacle (1) which has 
  - a conical zone (6) carrying means of entry for liquid (9) and containing a packing (10) for distributing the liquid, 
  - a first (7) and a second (8) cylindrical zone, the first zone (7) being of a cross-section smaller than that of the second zone (8), the zones being joined by a shoulder (11), 
  -the conical zone (6) and the first cylindrical zone (7) forming the dissolution chamber (24), 
  - a plug (2) comprising means for exit (15) of the solution, 
  - means of filtration (3) held between the plug (2) and the shoulder (11) and placed in the path of the solution between the dissolution chamber (24) and the means for exit (15) of the solution. 
 
<??>The cell and the apparatus incorporating it are used for the study of the kinetics of dissolution of pharmaceutical products. 
<IMAGE>
Patent DK-0497525-T3 (DK)
Inventor: KNISKERN PETER J
IPC: C07K14/41
Filed: 1992-01-27
Granted: 1998-10-26
Abstract: A novel conjugate vaccine comprising partially hydrolyzed, highly purified, capsular polysaccharide (Ps) from Streptococcus pneumoniae bacteria (pneumococci, Pn) linked to an immunogenic carrier protein, is produced by a new process. The conjugate is useful in the prevention of pneumococcal infections. Vaccines comprising a mixture of from one to ten different pneumococcal polysaccharideimmunogenic protein (Pn-Ps-PRO) conjugates induce broadly protective recipient immune responses against the cognate pathogens from which the polysaccharide components are derived. Young children and infants younger than 2 years old, normally unable to mount a protective immune response to the Pn-Ps alone, exhibit protective immune responses upon vaccination with these Pn-Ps-PRO conjugates.
Patent DK-0506420-T3 (DK)
Inventor: SMALL LAURA
IPC: A61F2/44
Filed: 1992-03-26
Granted: 1999-03-01
Abstract: A surgical spinal fixation system (10) includes a bone bolt (11) having first end portions (13) that are adapted to be surgically implanted into a patient's spine (S) at first and second spaced apart positions and a central portion (15) of the bone bolt (11) defining a load transfer surface, the bone bolt (11) having a second upper threaded sections (14) for threadably receiving a nut (31) at a shaped, countersunk interface (32). As an alternate embodiment, a bone screw (45) provides an upper enlarged head (48) with a lower coarsely threaded (47) shank (46). A plate (17) having upper (17A) and lower (17B) surfaces and outer opposed edges is provided with an elongated slot (20) for accommodating a selected bone bolt (11) or bone screw (45). The plate edges carry fine adjustments (27,28) extending between the upper (17A) and lower (17B) surfaces of the plate (17) and a load transfer washer (35) interfaces the plate (17) and the selected bone bolt (11) or bone screw (45) for distributing load (and reducing stress) from the bone bolt (11) (or screw (45)) to the plate (17).
Patent DK-0534707-T3 (DK)
Inventor: HOLTON ROBERT A
IPC: C07F7/18
Filed: 1992-09-22
Granted: 1997-06-09
Abstract: A taxane derivative of the formula <CHEM>  wherein     R<5> is phenyl or substituted phenyl,     R<7> is CH<7>O-, or CH<7>CH<6>O-,     Z is -OT<5>,     T<5> is hydrogen, hydroxyl protecting group, or -COT<6>, T<6> is H, C<5>-C1/4  alkyl, C<5>-C1/4  alkenyl, C<5>-C1/4  alkynyl or monocylic aryl,     Ac is acetyl, and E<5> and E<6> are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Patent DK-0544496-T3 (DK)
Inventor: SCATES MARK O
IPC: C07C51/47
Filed: 1992-11-24
Granted: 1996-07-01
Abstract: A method is provided for removing iodide compounds, particularly alkyl iodide compounds, from iodine-containing liquids, particularly carboxylic acids and anhydrides manufactured by the carbonylation of alcohols, ethers, esters, and the like in the presence of a rhodium catalyst and an alkali metal or alkaline earth metal salt, particularly a lithium salt, wherein the carboxylic acid or anhydride is contacted with a silver or mercury salt coordinated to a polymeric resin containing functional groups having the capability to quaternize with or form ionic salts with the alkyl halides.
Patent DK-0567704-T3 (DK)
Inventor: WOLF MICHAEL L
IPC: A61B17/08
Filed: 1992-12-11
Granted: 1997-08-25
Abstract: The present invention provides a wound dressing (10) in the form of a gauze or similar absorbent material (12) having dehydrated hydrogel material (14) impregnated therein for absorbing wound exudate. The present wound dressing (10) is capable of absorbing large amounts of wound exudate without inhibiting the healing of the wound to which it is contacted since it does not adhere to such a wound. <IMAGE>
Patent DK-0617575-T3 (DK)
Inventor: SPARKES ALEC GRAHAM
IPC: A01G7/00
Filed: 1992-12-18
Granted: 1997-09-01
Abstract: PCT No. PCT/GB92/02356 Sec. 371 Date Sep. 29, 1994 Sec. 102(e) Date Sep. 29, 1994 PCT Filed Dec. 18, 1992 PCT Pub. No. WO93/12644 PCT Pub. Date Jul. 8, 1993.The present invention relates to the propagation and growing of plants, and particularly concerns an apparatus for growing large numbers of plants in a small area, with optimized use of available and artificial light, and to reduce the effect of plants competing for light.
Patent DK-0634970-T3 (DK)
Inventor: HERTEL CHRISTOPHER J
IPC: B29C45/00
Filed: 1993-03-26
Granted: 1998-02-02
Abstract: A substantially microcrack- and blister-free composite can be made by drying an addition-type polyimide molding compound under suitable conditions to remove excess moisture. The molding compound includes a mixture of a polyimide resin and a plurality of carbon reinforcing fibers less than 3 mm long. The molding compound is placed into a heated material reservoir and transferred to a heated molding tool with a heated transfer ram. The ram establishes a molding pressure in a mold cavity in the molding tool sufficient to cure the molding compound into the desired composite. The molding compound is transferred to the mold cavity such that the molding compound is heated to a molding temperature at a rate of at least about 85 degrees C./min. The molding pressure and temperature are maintained in the mold cavity for a time sufficient to cure the molding compound into the desired composite. The composite is cooled and then heated to a suitable post-cure temperature at a rate sufficient to permit residual volatiles in the composite to diffuse out of the composite. The composite is held at the post-cure temperature for a sufficient time and then cooled. The invention also includes an article made by this method and a vented molding tool used in the method.
Patent DK-0608721-T3 (DK)
Inventor: GOET RICHARD CLAAS
IPC: B01D35/143
Filed: 1994-01-14
Granted: 1997-06-02
Abstract: A filtration apparatus with exchangeable filters for hygienic filtration of contaminated fluids. A tubular filter housing (1) has a central bore (2) as a receiving chamber for a filter cartridge. O-shaped rings (5,6) are mounted at the ends and in the centre of the wall of the receiving chamber, and these prevent fluid from leaking around the filter. The filter housing has a fluid entrance opening (7), and, diametrically opposite to it, an exit (8) lying lower. A filter cartridge has a filter element (11) and two end caps (13 and 14). The rear end cap (13) has an annular opening (16) which is in connection with the filter chamber (12) within the filter element. In an assembled state, the fluid entrance (7) is in connection with the annular opening (16) in the filter chamber. Contaminated fluid is sucked in through entrance (7) and it proceeds through the filter to fluid exit (8). The replacement of the filter takes places by pressing in a new filter cartridge at the top of the filter housing, which causes the soiled filter to be pressed out at the underside without this needing to be contacted by hand. <IMAGE>
Patent DK-0618242-T3 (DK)
Inventor: GERCHSHEIM HERBERT WOLTER DIPL
IPC: C07F7/18
Filed: 1994-03-02
Granted: 1998-10-26
Abstract: The invention relates to self-curing systems based on polymerisable and hydrolytically condensable or condensed silicon compounds. The systems according to the invention comprise one or more components containing initiator and/or activator systems, where at least one component of the system contains a silicon compound of the formula I and/or precondensates derived therefrom and/or condensates derived therefrom. <IMAGE>   The invention furthermore relates to activators in the form of silane-bonded, tertiary amines of the formula IX or X <IMAGE>
Patent DK-0643974-T3 (DK)
Inventor: SIMON MARKUS M DR
IPC: C12P21/08
Filed: 1990-09-18
Granted: 1999-09-06
Abstract: Production of active vaccine against Lyme disease comprises (i) culturing E. coli cells that have been transformed with the sequence encoding the 31 kD OspA antigen of Borrelia burgdorferi; (ii) recovering the antigen as an unfused protein and (iii) optionally formulating it with usual carriers, fillers and auxiliaries.
Patent DK-0714596-T3 (DK)
Inventor: FAHLBUSCH KLAUS
IPC: A61D7/00
Filed: 1994-11-25
Granted: 1998-09-21
Abstract: The animal feeding system allows the animal feed mixed with a medicament soln. to be pumped to each of the feeding stations (11) via a ring line (5, 105), with overall control of all functions of the feeding system by the central control device (16) in accordance with a selected feeding programme. The mixed feed and the medicament soln. are supplied to each feed point via separate ring lines, with individually controlled feed pumps (7, 107) and feed and return valves (9, 19; 109, 110).
Patent DK-0620254-T3 (DK)
Inventor: CHOPIN THIERRY
IPC: C09D7/62
Filed: 1994-04-08
Granted: 1996-09-23
Abstract: Novel compositions based on coloured rare-earth sulphides of core-shell type, which are characterised in that they include (i) a support based on at least one rare-earth sesquisulphide of formula M2S3 in which M denotes at least one element taken from the group consisting of the lanthanides of atomic number between 57 and 71 inclusive, preferably cerium, and yttrium, the said support additionally containing at least one alkali metal and/or alkaline-earth metal element, preferably sodium, at least a part of which, and preferably all of which, is included in the crystal lattice of the said sesquisulphide, and (ii) a layer based on at least one transparent oxide, preferably silica, deposited at the surface of the said support and coating the latter. The invention also relates to a process for obtaining these compositions, which consists (i) in bringing the support and a precursor of the desired transparent oxide into contact, (ii) in precipitating, according to a number of possible methods (hydrolysis, basic precipitation or other), the transparent oxide and, finally, (iii) in separating the composite obtained from its reaction mixture.   Finally, it relates to the use of the said compositions for colouring various materials, in particular plastics.
Patent DK-0669919-T3 (DK)
Inventor: BOSMANS JEAN-PAUL RENE MARIE A
IPC: A61P25/28
Filed: 1993-11-15
Granted: 1999-09-13
Abstract: PCT No. PCT/EP93/03206 Sec. 371 Date Jun. 16, 1995 Sec. 102(e) Date Jun. 16, 1995 PCT Filed Nov. 15, 1993 PCT Pub. No. WO94/12494 PCT Pub. Date Jun. 9, 1994Method of treating 5-HT3-mediated disorders, which comprises systemic administration of an effective amount of a compound of formula (I)    <IMAGE>  (I)  the pharmaceutically acceptable acid addition salt forms and the stereochemically isomeric forms thereof, wherein R1 and R2 represent hydrogen, or R1 and R2 taken together form a bivalent radical of formula -CH=CH-CH=CH- (a), -CH=C(Cl)-CH=CH- (b) or -CH=CH-C(Cl)=CH- (c); n represents 2, 3 or 4; R3 represents hydrogen or methoxy; m represents 1 or 2; R4 represents hydrogen, amino or C1-3-alkylcarbonylamino; and R5 represents hydrogen or halo; novel compounds; compositions; processes for preparing novel compounds and intermediates.
Patent DK-0741556-T3 (DK)
Inventor: HARRIS DALE C
IPC: A61J1/20
Filed: 1994-03-14
Granted: 1999-11-15
Abstract: A cartridge assembly for holding a lyophilized product, forming a disposable portion of a pen injector includes a cylindrical glass cartridge adapted to receive the product, a closure cap, a cartridge case, and a plunger mechanism. The closure cap is adapted to retain an elastomeric disc seal during lyophilization and includes diametrically opposed ledges. The closure cap and seal are adapted to cover a neck portion of the ampule, the neck portion having on its end a radially extending circumferential flange. The ledges of the closure cap and the flange of the neck portion allow the closure cap to remain open during lyophilization, oxygen purge and nitrogen overlay. An oval-shaped indentation formed on the inside of the closure cap aids in snapping the closure cap about the flange without crimping to retain the closure cap underneath the flange. Reconstitution of the lyophilized drug is accomplished without foaming by use of an obliquely angled connector which causes the diluent to indirectly impinge on the drug. The injection pen and cartridge assembly cooperate such that the length of travel of the plunger rod during retraction is less than the axial length of a recess in the rod tip.
Patent DK-0648107-T3 (DK)
Inventor: PARADOT FRANCE
IPC: A61K8/34
Filed: 1994-05-06
Granted: 1999-06-21
Abstract: Composition for enhancing hair growth or stopping hair loss, containing, in a hydroalcohol or aqueous medium comprising water and an alkylene glycol or polyalkylene glycol liquid at room temperature: a) at least 0.03 to 0.3 weight percent of fructose; b) at least 0.002 to 0.05 weight percent of glucose; c) at least 0.03 to 0.2 weight percent of one or more cereal spheroproteins or their hydrolysates; d) at least 0.03 to 1 weight percent of a sodium or potassium salt.
Patent DK-0705265-T3 (DK)
Inventor: CAVALLA DAVID
IPC: A61K31/52
Filed: 1994-06-21
Granted: 2000-03-13
Abstract: Novel purine derivatives and their isoguanine and dithioxanthine precursor compounds are disclosed. These compounds have bronchial and tracheal relaxation and/or anti-inflammatory activity. The invention is also related to processes for their preparation, to pharmaceutical compositions containing them and to their medical use. In certain preferred embodiments, the invention relates to 3-substituted and 3,8-disubstituted 6-amino purine derivatives.
Patent DK-0707570-T3 (DK)
Inventor: SARGENT BRUCE JEREMY
IPC: A61P21/00
Filed: 1994-06-10
Granted: 1998-10-07
Abstract: PCT No. PCT/EP94/01926 Sec. 371 Date Dec. 21, 1995 Sec. 102(e) Date Dec. 21, 1995 PCT Filed Jun. 10, 1994 PCT Pub. No. WO95/00489 PCT Pub. Date Jan. 5, 1995Tetrahydroisoquinoline compounds of formula I    <IMAGE>  I  and pharmaceutically acceptable salts thereof, in which: R1 represents one or more substituents selected from H, halo, hydroxy, alkyl (optionally substituted by hydroxy), alkoxy, alkylthio, alkylsulphinyl, alkyl-sulphonyl, nitro, cyano, polyhaloalkyl, polyhaloalkoxy, phenyl (optionally substituted by one or more of halo, alkyl or alkoxy), or R1 is optionally alkylated carbamoyl; R2 represents a saturated or unsaturated aliphatic group optionally substituted by hydroxy or alkoxy; E represents an alkylene chain optionally substituted by one or more alkyl groups; and G represents (a) optionally substituted saturated or unsaturated alicyclic group containing 3 to 8 carbon atoms, or (b) optionally substituted saturated or unsaturated aliphatic chain containing 1 to 12 carbon atoms, or (c) optionally substituted 5 or 6 membered heterocyclic ring containing one or more N or O atoms or SOn groups in which n is 0, 1 or 2; and O-acylated derivatives thereof which provide lipophilic esters have utility in analgesia or in the treatment of psychoses (e.g. schizophrenia), Parkinson's disease, Lesch-Nyan syndrome, attention deficit disorder or cognitive impairment or in the relief of drug dependence or tardive dyskinesia.
Patent DK-0711586-T3 (DK)
Inventor: NIELSEN KENNETH ANDREW
IPC: B01J37/02
Filed: 1995-11-13
Granted: 2000-12-27
Abstract: This invention relates to methods for spraying liquid compositions containing volatile solvent by using compressed fluids, such as carbon dioxide or ethane, to form solid particulates, coating powders, and catalyst materials, which can be produced with narrow particle size distributions and can be sprayed at higher solids levels, in ambient air or with heated air applied to just the spray instead of a spray chamber. Novel catalyst supports can be produced having a beneficial morphology such as for olefin catalysis. Drier water-borne coatings can be applied to substrates by using compressed fluids to spray water-borne coating compositions having conventional water levels, thereby reducing runs and sags and shortening dry times.
Patent DK-0722963-T3 (DK)
Inventor: SCHNEIDER VOLKER DR
IPC: C08G18/40
Filed: 1996-01-11
Granted: 2000-08-28
Abstract: The prodn. of aq. binders (I) for aq. coating materials comprises reacting a mixt. of (A) 9.9-85 wt.% OH- and acid-functional poly(meth)acrylate component, and (B) 14.9-90 wt.% OH-functional, fatty acid-modified polyester component, with (C) 0.1-20 wt.% of a di-isocyanate component contg. at least one di-isocyanate with a mol. wt. of 140-318, to form a urethane and then dissolving and/or dispersing the prod. in water with simultaneous or prior neutralisation of at least some of the COOH gps. Also claimed are aq. binders (I) obtd. by this process.