baber/WOPTO huggingface dataset:
Patent AU-2019264674-A1 (AU)
Title: Attachment arrangement
Inventor: GRIBBIN PAUL
IPC: H01R4/60
Filed: 2019-11-15
Abstract: ATTACHMENT ARRANGEMENT 
The invention relates to an attachment arrangement (1000) adapted for electrical attachment 
to a conductive member (2000). The attachment arrangement (1000) comprises a frame (100) 
adapted for electrical connection with the conductive member (3000). The frame (100) 
includes at least one connector (102) for electrical connection of an electrical cable to the 
frame and at least one attachment member (104) attached to the frame (100) and adapted to 
receive a first end (5000) of an flexible elongate member (3000) for attachment to the at least 
one attachment member (104) in use and at least one take up spool (106) rotateably mounted 
to the frame and adapted to securely receive a second end (6000) of the flexible elongate 
member (3000) in use. The at least one take up spool (106) is further adapted to receive a 
tool to aid in a rotation of the take up spool (106) in use and a one way device (108) associated 
with the take up spool (106) to restrict its rotation to one direction.
1/4 
1000 
108 100 106 
a108 
Fig. la 102 Fig. 1c 120 100 
106 120104 
106 104 102 
104 - 100 110 
- 0114 
107 101110 
Fig. lb 104 Fig. 1d 108 
112
Patent AU-2019269713-A1 (AU)
Title: System and method for tracking resection planes
Inventor: MITRA RIDDHIT
IPC: A61B17/15
Filed: 2019-05-20
Abstract: A system for tracking resection planes during a surgical procedure includes a cutting block and a position tracker. The cutting block is configured to be mounted on an anterior surface of a bone during the surgical procedure. The cutting block comprises at least one slot configured to position a resection tool during the surgical procedure. The position tracker is configured to be directly attached to the cutting block after the cutting block is mounted on the anterior surface to allow positional tracking of the cutting block by a tracking device during the surgical procedure.
Patent AU-2019316802-A1 (AU)
Title: Method for obtaining a brass billet with reduced lead content and the billet thus obtained
Inventor: GNUTTI GABRIELE
IPC: C22F1/08
Filed: 2019-08-05
Abstract: A method for obtaining a brass billet with a reduced lead content provides for machining a finished or semi-finished product made of traditional brass by chip removal and obtaining traditional brass chips, and performing a fragmentation treatment on said traditional brass chips to obtain traditional brass fragments; performing a lead removal treatment on said traditional brass fragments to obtain brass fragments with a reduced lead content; melting in a furnace a charge comprising said brass fragments with a reduced lead content; obtaining a billet by direct or inverted extrusion of the molten product.
Patent AU-2019335203-A1 (AU)
Title: Methods of treating mycobacterial infections using tetracycline compounds
Inventor: CYNAMON MICHAEL HENRY
IPC: A61K31/5377
Filed: 2019-09-03
Abstract: The present invention provides methods of treating mycobacterial infections or mycobacterial diseases by administering a tetracycline compound, e.g., omadacycline, or a pharmaceutically acceptable salt thereof.
Patent AU-2019348135-A1 (AU)
Title: Fused tetracyclic compounds and uses thereof in medicine
Inventor: HUANG JIANZHOU
IPC: A61P31/20
Filed: 2019-09-27
Abstract: There is provided a fused tetracyclic compound and application thereof in medicine, especially as a medicament for the treatment and/or prevention of hepatitis B. In particular, there is provided a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, wherein each variable is as defined in the specification. There is provided the use of a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof in medicine, especially as a medicament for the treatment and/or prevention of hepatitis B.
Patent AU-2019368318-A1 (AU)
Title: Methods, devices, and systems for physiological parameter analysis
Inventor: XU YONGJIN
IPC: G01N33/72
Filed: 2019-10-25
Abstract: A method of calculating at least one physiological parameter using a reticulocyte production index (RPI) value including: measuring a plurality of first glucose levels over a first time period; measuring a first glycated hemoglobin (HbA1c) level corresponding to an end of the first time period; measuring the RPI value; calculating a red blood cell elimination constant (kage) based on the RPI value; and calculating the at least one physiological parameter selected from the group consisting of: a red blood cell glycation rate constant (kgly), a red blood cell generation rate constant (kgen), and an apparent glycation constant (K), based on (1) the plurality of first glucose levels, (2) the first HbA1c level, and (3) the kage. Further, one or more related analyses (e.g., personalized-target glucose range, personalized-target average glucose, cHbA1c, and the like) can be estimated and/or adjusted based on the at least one physiological parameter.
Patent AU-2019391097-A1 (AU)
Title: CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
Inventor: SIDDIQUI-JAIN ADAM
IPC: A61K31/675
Filed: 2019-12-04
Abstract: A crystalline form and/or polymorph of a compound having the following structure (I), including tautomeric and zwitterionic forms thereof, are provided: Methods associated with preparation and use of the polymorphs, and pharmaceutical compositions comprising the same are also provided. Also provided are methods for preparing a compound having formula (I), or a salt, tautomer or zwitterionic form thereof.
Patent AU-2019392928-A1 (AU)
Title: Oligonucleotide compositions and methods thereof
Inventor: ZHANG JASON JINGXIN
IPC: C12N15/113
Filed: 2019-12-06
Abstract: Among other things, the present disclosure provides designed DMD oligonucleotides, compositions, and methods of use thereof. In some embodiments, the present disclosure provides technologies useful for repairing mutant DMD transcripts by skipping exon 51, so that the transcript can be translated into an internally truncated but at least partially functional Dystrophin protein variant. In some embodiments, the present disclosure provides technologies useful for modulating DMD transcript splicing. In some embodiments, provided technologies can alter splicing of a dystrophin (DMD) DMD transcript. In some embodiments, the present disclosure provides methods for treating diseases, such as muscular dystrophy, including but not limited to Duchenne muscular dystrophy, Becker's muscular dystrophy, etc.
Patent AU-2020201283-A1 (AU)
Title: Dental surgery method and device
Inventor: CASTLE CAMERON GLENN
IPC: A61C1/08
Filed: 2020-02-21
Abstract: A device for detaching a tooth root. The device comprises: a lead screw having a threaded point for screwing into the tooth root, and a threaded shaft; a pivoting member including a bore through which the lead screw passes, the lead screw being retractable through the bore by rotational engagement of a threaded member with the threaded shaft of the lead screw; and a platform for supporting the pivoting member such that the lead screw is able to pivot relative to the platform, The lead screw includes a locking surface for preventing rotation of the lead screw during rotational engagement of the threaded member with the threaded shaft. co CD CD C)
Patent AU-2020201855-A1 (AU)
Title: Progressive cavity pump and methods for using the same
Inventor: COTE BRENNON LEIGH
IPC: E21B43/00
Filed: 2020-03-13
Abstract: A device is provided for pumping fluid from a wellbore up to surface. The device includes a 
stator unit, a rotor unit run within the stator unit on a rod string, the rotor unit and the stator 
unit engaging with one another to form an annular space therebetween for passage of fluid. An 
5 upstream check valve on the rod string uphole of the rotor unit is moveable from an open 
position in which fluid is passable through the annular space, and a closed position in which 
fluid passage through the annular space is prevented. A hollow rod section extends through 
the rod string in fluid communication with the annular space both downstream and upstream 
of the upstream check valve, for entry of fluid into a downhole end of the hollow rod section, 
0 passage of fluid upstream therefrom and exit of fluids from an uphole end of the hollow rod 
section, back into the annular space. A method is further provided for pumping fluid from a 
wellbore after shutdown.  
12354878-1 10869951-1 11
4 
-13 
1A 
Figure 
1B 
2 A 
A 10 
Figure 
1A 
12 
6 
7 
Figure 1
Patent AU-2020205923-A1 (AU)
Title: Internal cyclic sulphiamidine amide-aryl amide compound and use thereof for treating hepatitis B
Inventor: WANG ZHE
IPC: A61K31/407
Filed: 2020-01-10
Abstract: The invention relates to an internal cyclic sulphiamidine amide-aryl amide compound and a use thereof for treating hepatitis B. Specifically, disclosed is a compound that may act as an HBV replication inhibitor and that has a structure represented by chemical formula (L), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt, a hydrate or a solvent thereof. See the description for detailed definitions of each group. The present invention also relates to a pharmaceutical composition containing the compound and a use thereof for treating hepatitis B.
Patent AU-2020210195-A1 (AU)
Title: Flexible electrical isolation device
Inventor: WABNEGGER DAVID KARL
IPC: H02G15/24
Filed: 2020-07-29
Abstract: An electrical isolator includes a flexible non-electrically conductive membrane and an 
inelastic flexible dielectric member journalled in the membrane and extending from 
the first end of the membrane to the second end of the membrane. First and second 
5 coupling members are anchored to the ends of the dielectric member. The ends of 
the membrane are mated in sealed engagement with the coupling members so that 
the coupling members fluidically seal the ends of the membrane and fluidically seal 
the dielectric member within the membrane. The membrane is filled with a dielectric 
fluid so as to displace any air in the membrane and the dielectric member. The 
0 coupling members are adapted to couple to objects at opposite ends of the electrical 
isolator.
WO 2015/143402 PCT/US2015/021876 
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Patent AU-2020213296-A1 (AU)
Title: IL-2Rbeta-selective agonists in combination with an anti-CTLA-4 antibody or an anti-PD-1 antibody
Inventor: ADDEPALLI MURALI KRISHNA
IPC: A61K39/395
Filed: 2020-08-04
Abstract: The invention relates to (among other things) method of 
administering to a patient suffering from a cancer, the 
5 method comprising the steps of: (a) an IL-2Rf-activating 
amount of a long acting, IL-2Rf-selective agonist; and (b) 
a CTLA-4 pathway-inhibiting amount of an anti-CTLA-4 
antibody or a PD-1 pathway-inhibiting amount of an anti
PD-1 antibody.  
W:\NRPortbl\GHMatters\MICHELES\13180196_1.docx7/07/20
Patent AU-2020216127-A1 (AU)
Title: Cell populations with improved production and therapeutic characteristics
Inventor: WARD ANTHONY
IPC: C12N5/0783
Filed: 2020-01-28
Abstract: The present invention is directed to improved methods of preparing cells and compositions for therapeutic uses.
Patent AU-2020222903-A1 (AU)
Title: Tie switch restoration
Inventor: QUINLAN MICHAEL
IPC: G05F1/66
Filed: 2020-02-11
Abstract: A control system and method for a group of interconnected feeders which enables fault location, isolation and service restoration without requiring each switch to have topology knowledge of devices in adjacent feeders. The method defines, for each switch, connectivity and X/Y directional information about its neighboring switches and propagates this information throughout each feeder. A leader device is also determined for each feeder. Information about topology of adjacent feeders is not needed by all devices. Only normally-open tie switches which define a boundary between two adjacent feeders have knowledge of the devices in both feeders. Switches which open during fault isolation automatically find open tie switches in a direction opposite the fault, and request service restoration downstream of the fault by providing power from an adjacent feeder. Leader devices ensure an overload condition is not created before initiating opening and closing operations of switches downstream of the fault.
Patent AU-2020226498-A1 (AU)
Title: Methods for producing autologous T cells useful to treat cancers and compositions thereof
Inventor: LANGER TIMOTHY J
IPC: A61P35/00
Filed: 2020-02-18
Abstract: Provided herein are methods for manufacturing T cells. In certain embodiments, methods for manufacturing T cells which express a novel group of cell surface receptors that recognize peptides on the surface of a target cell are provided. Also provided herein are populations of T cells produced by methods described herein and pharmaceutical compositions thereof.
Patent AU-2020241411-A1 (AU)
Title: CD28 T cell cultures, compositions, and methods of using thereof
Inventor: ALPERT AMIR
IPC: C12N5/0783
Filed: 2020-03-19
Abstract: A method for producing T cells with improved efficacy for adoptive immunotherapy includes obtaining a population of CD8+ T cells from a patient or a donor, determining a % of CD28+ CD8+ T cells in the obtained population, activating the determined population with anti-CD3 antibody and anti-CD28 antibody, provided that the determined population comprises at least 50% of CD28+ CD8+ T cells, or activating the determined population with anti~CD3 antibody in the absence of anti-CD28 antibody, provided that the determined population comprises less than 50% of CD28+ CD8+ T cells, transducing the activated population with a viral vector, and expanding the transduced population, in which the transducing and the expanding are carried out in the presence of at least one cytokine.
Patent AU-2020242318-A1 (AU)
Title: Cancer treatment comprising naltrexone and a cannabinoid
Inventor: LIU WAI
IPC: A61K31/352
Filed: 2020-03-13
Abstract: The present invention is based on the finding that the inhibition of the proliferation of cancer cells by cannabinoids is brought about more effectively by combined treatment with low dose naltrexone (LDN) or 6-β-naltrexone (6BN), a metabolite of naltrexone. There is provided a pharmaceutical composition comprising naltrexone or a metabolite thereof or an analogue thereof, for use in the treatment of cancer within a subject, wherein a therapeutically effective amount of the naltrexone or metabolite thereof or analogue of either is to be administered to the subject in a first treatment phase, wherein after the first treatment phase the subject is to be administered a therapeutically effective amount of a cannabinoid in a second treatment phase, and wherein the subject is to be administered a chemotherapeutic agent before, during or following the treatment.
Patent AU-2020242565-A1 (AU)
Title: Lubricant dispenser
Inventor: EISENBACHER EGON
IPC: F16N11/08
Filed: 2020-02-13
Abstract: The invention relates to a lubricant dispenser comprising a storage container (1) filled with lubricant and a pump (2) which is connected to or can be connected to the storage container (1) and by means of which the lubricant can be pumped out of the storage container (1). The pump has a pump housing (3) with an inlet opening (4) and an outlet opening (5), a piston (6) which is movably guided in the pump housing (3) in a linear manner, and a drive (7) which acts on the piston (6). The pump housing (3) of the pump (2) is connected to or can be connected to the storage container (1), and the piston (6) can be raised or lowered cyclically by the drive (7) in order to pump a lubricant from the inlet opening (4) to the outlet opening (5). The lubricant dispenser is characterized in that the piston (6) is designed in a stepped manner with an upper piston surface (10) which delimits an upper displacement chamber (8) and a lower piston surface (11) which delimits a lower displacement chamber (9) and is reduced compared to the upper piston surface (10). The upper displacement chamber (8) adjoins the inlet opening (4) via a first valve (13), and the first valve (13) is loaded or can be loaded into a closed base position. A through-opening (12a, 12b) which connects the upper displacement chamber (8) to the lower displacement chamber (9) with the interposition of a second valve (14) is arranged in or on the piston (6), and the lower displacement chamber (9) transitions into the outlet opening (5) via an outlet channel (16). When the piston (6) is lowered as the result of a negative pressure in the upper displacement chamber (8), the first valve opens (for example against a spring force), and lubricant is suctioned out of the storage container into the upper displacement chamber (8), but the second valve (14) closes and lubricant is pushed out of the lower displacement chamber (9) into the outlet channel (16). When the piston (6) is raised, the first valve (13) closes, but the second valve (14) opens in the piston (6), and lubricant both flows from the upper displacement chamber (8) into the lower displacement chamber (9) and is pushed from the lower displacement chamber (9) into the outlet channel (16).
Patent AU-2020253356-A1 (AU)
Title: Immunotherapeutic compositions and use thereof
Inventor: JONES DOUGLAS
IPC: C07K14/54
Filed: 2020-03-30
Abstract: Combination therapties for the treatment of cancer comprising an immunostimulatory fusion molecules that include an immune cell targeting moiety and a cytokine molecule; and an immune cell loaded with protein nanogels that include a reversibly crosslinked cytokine molecule and a polymer, pharmaceutical and formulations thereof, and methods of using and making the same, are disclosed.
Patent AU-2020261207-A1 (AU)
Title: Monoclonal antibody that specifically binds to GITR
Inventor: ULITIN ANDREI BORISOVICH
IPC: C12P21/08
Filed: 2020-04-23
Abstract: The present invention relates to the field of biotechnology, and particularly to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to monoclonal antibodies that bind specifically to GITR. The invention also relates to a nucleic acid that codes for said antibody or for an antigen-binding fragment thereof, an expression vector, a method for producing the antibody, and the use of said antibody for treating diseases or disorders associated with GITR.
Patent AU-2020267167-A1 (AU)
Title: Trampoline frame and trampoline with the trampoline frame hereof
Inventor: WANG YONGQI
IPC: A63B5/11
Filed: 2020-06-30
Abstract: A trampoline frame formed by multiple frame pipes connected in turns, 
the adjacent two frame pipes are connected by a frame connector, which is a 
T-shaped pipe composed of a horizontal pipe and a vertical pipe; the outer diameter 
of the horizontal pipe is smaller than the inner diameter of the frame pipe; two ends 
of the horizontal pipe are inserted into the adjacent two frame pipes respectively so 
as to form a closed trampoline frame; the top surface and the bottom surface of the 
frame pipe are provided with upper frame holes and lower frame holes respectively, 
and said upper frame holes and said lower frame holes are staggered in pairs; the 
top surface and the bottom surface of the horizontal pipe are provided with upper 
insert holes and lower insert holes respectively, the upper insert holes and the lower 
insert holes are staggered in pairs.  
1
Patent AU-2020281922-A1 (AU)
Title: Conductive circuit
Inventor: LAY GRAHAM
IPC: A61N1/36
Filed: 2020-05-28
Abstract: In general terms, the invention provides a circuit for delivering an electromagnetic signal to a human or animal body via contact with the skin of the body. The circuit comprises a plurality of printed layers provided on a base. The plurality of printed layers includes a first printed layer, and a second printed layer having a portion that overlays the first printed layer and a portion that overhangs the first printed layer. Optionally the portion that overhangs the first printed layer contacts the base or another of the printed layers of the plurality of printed layers.
Patent AU-2020294642-A1 (AU)
Title: Indazole derivative, preparation method therefor, and pharmaceutical application thereof
Inventor: FAN XING
IPC: C07D401/14
Filed: 2020-06-18
Abstract: An indazole derivative, a preparation method therefor, and a pharmaceutical application thereof. In particular, the present invention relates to an indazole derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition comprising the derivative, and a use of the derivative as an estrogen receptor modulator in the prevention and/or treatment of an estrogen receptor mediated or dependent disease or condition, the disease being particularly preferably breast cancer. The definition of each substituent in the general formula (I) is the same as that in the description.
Patent AU-2020294852-A1 (AU)
Title: System and method for preparing a catheter before use
Inventor: VISSER JOHANNES
IPC: A61M60/174
Filed: 2020-06-15
Abstract: A system and method are disclosed in the field of preparing a catheter (1) for use in a patient, in particular a catheter (1) of an intravascular blood pump (10), more specifically for properly purging and de-airing the catheter (1). The catheter (1) comprises an elongate tubular portion (11) and a connected device (230). The elongate tubular portion (11) is configured to be inserted into a patient's blood vessel and defines a lumen (12). The connected device (230) is connected to the elongate tubular portion (11) and has a cavity (13), which may accommodate a drive unit (4) of the blood pump (10), and which is in fluid communication with the lumen (12) of the elongate tubular portion (11). In order to securely de-air the system (100), a sensor (15), such as an accelerometer, for detecting an orientation of the connected device (230) is provided, and a user may be guided to correct the orientation of the connected device (230) for proper purging.
Patent AU-2020297401-A1 (AU)
Title: Pump assembly and container having content discharge function
Inventor: ZHU WEI
IPC: B65D47/34
Filed: 2020-06-09
Abstract: Provided are a pump assembly (90) and a container (900) having a content (800) discharge function; the pump assembly (90) comprises a pump body (1) and a pressure rod (2); the pump body (1) comprises an inner housing (12); the inner housing (12) has an inner housing top wall (120), a first inner housing side wall (121), and a second inner housing side wall (122); the outer wall of the first inner housing side wall (121), the inner wall of the second inner housing side wall (122), and the inner housing top wall (120) define a first cavity (1a) having a first opening (1b); a first air cavity (12a) of the first cavity (1a) is a sealed cavity collectively defined by a piston part (21), the inner housing top wall (120), the outer wall of the first inner housing side wall (121), and the inner wall of the second inner housing side wall (122). The container (900) having the content (800) discharge function comprises the pump assembly (90).