baber/WOPTO huggingface dataset:
Patent NZ-503782-A (NZ)
Title: Cyclic amine derivatives and chemokine receptor antagonists that are effective in treating disease caused by infiltration of the tissue by blood leukocytes
Inventor: SUDOH MASAKI
IPC: A61K31/433
Filed: 1998-11-17
Abstract: Described are compounds represented by the general formula (I) wherein R1 is a phenyl group, a C3-C8 cycloalkyl group, or an aromatic heterocyclic group having 1-3 heteroatoms, and R2 is a hydrogen atom, a C1-C6 alkyl group, a C2-C7 alkoxycarbonyl group, a hydroxy group, or a phenyl group in which the C1-C6 alkyl or phenyl group may be substituted with one of more of a halogen atom, a hydroxy group, a C1-C6 alkyl group, or a C1-C6 alkoxy group, and R3 is hydrogen atom or a C1-C6 alkyl group optionally substituted with one or two phenyl groups each of which may be substituted with one or more of a halogen atom, a hydroxy group, a C1-C6 alkyl group, or a C1-C6 alkoxy group, and R4 and R5 are the same of different from each other and are a hydrogen atom, a hydroxy group, a phenyl group or a C1-C6 alkyl group, and R6 is a phenyl group, a C3-C8 cycloalkyl group, a C3-C8 cycloalkenyl group, a benzyl group, or an aromatic heterocyclic group having 1-3 heteroatoms selected from the group consisting of an oxygen atom, a sulphur atom, a nitrogen atom, or a combination thereof, and j represents an integer of 0-2, and k represents an integer of 0-2, and m represents an integer of 2-4, and n represents 0 or 1, and p represents 0 or 1, and q represents 0 or 1, and G is a group represented by -CO-, SO2-, -CO-O-, -NR7-CO-, -CONR7-, -NH-CO-NH-, -NH-CS-NH-, -NR7-SO2-, -SO2-NR7-, -NH-CO-O-, or -O-CO-NH-, wherein R7 is a hydrogen atom or a C1-C6 alkyl group, or R7 taken together with R5 represents C2-C5 alkylene group. These compounds inhibit the action of chemokines such as MIP-1 alpha and/or MCP-1 on target cells, they may be useful as a therapeutic drug and/or preventative drug in diseases where blood monocytes and lymphocytes infiltrate into tissues, such as atherosclerosis and rheumatoid arthritis.
Patent NZ-506318-A (NZ)
Title: Methacrylic resin board used for producing bathtubs and basins
Inventor: MIZUMOTO TOMOHIRO
IPC: C08L51/00
Filed: 2000-08-14
Abstract: Methacrylic resin board is provided for producing sanitary articles such as a bathtub and a washing bowl, having an elongation at break of from 700% to 1000% and a creep index greater than 1x106 Pa. The resin board comprises 5 to 35 parts by weight of a methyl methacrylate based polymer having a viscosity average molecular weight of 50 000 to 300 000, 65 to 95 parts by weight of a methyl methacrylate based monomer, 0.1 to 0.5 part by weight of a polyfunctional monomer copolymerisable with the methyl methacrylate based monomer, and 0.01 to 0.3 part by weight of a chain transfer agent having an alkyl mercaptan content of greater than 80% by weight.  The molar ratio of the alkyl mercaptan contained in the chain transfer agent to the polyfunctional monomer is 1.5 to 3.5.
Patent NZ-508833-A (NZ)
Title: Levosimendan is used to treating pulmonary hypertension
Inventor: LEHTONEN LASSE
IPC: A61P9/12
Filed: 1999-06-18
Abstract: Levosimendan, or (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]-propanedinitrile is used to treat pulmonary hypertension.
Patent NZ-508842-A (NZ)
Title: Novel form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same
Inventor: FRANC BRUNO
IPC: A61P25/00
Filed: 1999-06-10
Abstract: Crystalline Irbestan Form A having a structure such that the ratio of length/width is between 1:1 and 10:1, processes for its preparation, and pharmaceutical compositions containing it are disclosed. Irbestan is of formula (I). Known crystals of this material are needle-shaped, but the new crystalline structure preferably has a length/width ratio of 1:1 to 5:1. This new form is prepared by either of the following methods: (1) a suspension of crystalline (I) Form A is submitted to at least one period of sonification, and at least one of temperature oscillation, conducted simultaneously or sequentially. Preferably the heating phase in the temperature oscillation is effected so that 15 - 25% of the crystals dissolve after about 60 minutes. The cooling phase is preferably carried out at -5 to +20 deg C; (2) Needles of (I) are dissolved in an alcohol, the solution is cooled to a temperature at which, at the given concentration the solution enters a metastable state, and this is then seeded with crystals of the new Form A. The resulting crystalline suspension is mechanically sheared, the mixture is re-heated to dissolve the fine particles, and the suspension cooled to 5 - 20 deg C and filtered.
Patent NZ-510812-A (NZ)
Title: Novel peptides
Inventor: SHARPE IAIN ANDREW
IPC: A61P25/04
Filed: 1999-10-01
Abstract: This invention relates to an isolated, synthetic or recombinant rho -conotoxin peptide having selective alpha 1- adrenoceptor antagonist activity, nucleic acid molecules encoding all or part of such peptides, antibodies to such peptides and uses and methods of treatment involving them.
Patent NZ-511027-A (NZ)
Title: Quality sorting of fruit by passing light through the fruit
Inventor: KENNEDY HAMISH ALEXANDER NIGEL
IPC: G01N21/41
Filed: 1999-09-07
Abstract: A method and apparatus for sorting products includes a flexible concertina-like shield (3) sealingly engaging a portion of the surface of the product (2) at one end to receive electromagnetic radiation transmitted through the product, at the other end of the shield electromagnetic radiation receiving means (4) is positioned and a control means to selectively position the shielding means at or about the product selected (fig 3).
Patent NZ-511148-A (NZ)
Title: Bone alignment system having variable orientation bone anchors
Inventor: CARSON WILLIAM L
IPC: A61B17/70
Filed: 1999-10-07
Abstract: A bone alignment assembly (20) is disclosed having bone anchor subassemblies (26) for securing to both bones (32), and a bone position retainer (24), wherein the bone position retainer (24) includes a longitudinal member (24a) for maintaining a desired alignment of the bones (32) when the bone anchor assemblies (20) are secured to the bone position retainer (24). Each of the bone anchor subassemblies (26) includes a shaft (36), and one or more pairs of components (e.g., washers (68, 94)) wherein the components of each pair have mating spherical concave (72), and convex (68) surfaces that can mate together in a plurality of angular positions. When the shaft (36) extends through each of the pairs of mating components (68, 94), and also through a passageway (28) of the bone position retainer (24) that is sandwiched between the two pairs of mating components (68, 94), the shaft (38) can be secured at any one of a plurality of orientations relative to the bone position retainer (24)
Patent NZ-512558-A (NZ)
Title: Apparatus for the alignment and depositing of elongate particles such as wood chips, wood fibers or the like parallel to a continuously moved support
Inventor: IREDI HANS-JOACHIM
IPC: B65G47/14
Filed: 1998-04-20
Abstract: An apparatus for the alignment and depositing of elongate particles containing lignocellulose and/or cellulose such as wood chips, wood fibres or the like provided with a binder, to form a mat for the subsequent manufacture of boards comprising a metering hopper (1), a unit      (2,3) for the transfer of the particles onto an orientation unit (4) which is arranged above a continuously moving support (10).  The spacing between the orientation unit (4) and the continuously moving support (10) lies higher than the upper side of the mat to be formed.  The orientation unit (4) has a plurality of separation rolls (5), which extend over the width of the moving support (10), a first group rotating clockwise and the other group counterclockwise.  The particles fall onto compartmented rolls (7) arranged beneath the separation rolls (5) and are rotationally driven opposite to the direction of the moving support (10).
Patent NZ-516664-A (NZ)
Title: Formulations and compositions for interleukin-11
Inventor: WARNE NICHOLAS W
IPC: A61K9/19
Filed: 2000-07-14
Abstract: Interleukin 11 ("IL-11") is a pleiotropic cytokine that stimulates a variety of hematopoietic and immune functions, such as primitive lymphohematopoietic progenitor cells and other hematopoietic growth factors, which stimulate the proliferation and maturation of megakaryocytes.  Different compositions and methods for obtaining concentrated preparations of IL-11 and formulations of IL-11 suitable for storage and administration are disclosed.
Patent NZ-520409-A (NZ)
Title: Bin structures and their formation
Inventor: HEWITT WALLACE NORMAN
IPC: B65D5/32
Filed: 2002-07-25
Abstract: In combination, four bin wall panels, two being of at least substantially identical dimensions and two others being of different at least substantially identical dimensions but which panels, when associated with each other, end region against end region, is capable of defining a bin wall assembly of rectangular or square plan and are capable of being held in such association by multiple hook in loop type engagements.
Patent NZ-523987-A (NZ)
Title: Indole, azaindole and indazole derivatives having VEGF inhibiting activity
Inventor: HENNEQUIN LAURENT FRANCOIS AND
IPC: A61P9/10
Filed: 2001-08-08
Abstract: Indole, azaindole and indazole derivative compounds of the formula (Ib) which are useful for the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals are disclosed, wherein the variables shown in formula (Ib) are as defined in the specification. These compounds of formula (Ib) and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, which makes them suitable for use in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent NZ-529341-A (NZ)
Title: A biomedical cermet comprising metal phase and a ceramic phase for bone implants
Inventor: YING DANYANG
Filed: 2004-05-04
Abstract: The present invention relates to ceramic metal composites and to processes for the production thereof. More particularly but not exclusively it relates to metal-ceramic composites of biocompatible metals and bioactive ceramics.
Patent NZ-530489-A (NZ)
Title: A heating appliance
Inventor: ALDRIDGE WAYNE KENNETH
IPC: F24D18/00
Filed: 2002-12-18
Abstract: A heating appliance comprising first and second burners, a supply of air, a splitter valve for splitting the supply of air into a stream feeding the first burner and a stream feeding the second burner, means for feeding combustible fuel to mix with the air and a controller for controlling the combustible fuel flow and the proportion of the air fed to each burner depending on the appliance requirements; characterised in that the splitter valve is a single valve positioned upstream of the two burners.
Patent NZ-532288-A (NZ)
Title: 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as PDE-4 inhibitors for the treatment of neurological syndromes
Inventor: LIU RUIPING
IPC: A61P9/10
Filed: 2002-10-16
Abstract: A compound of formula I is described to be used in the manufacture of a medicament for enhancing cognition. X is O; R1 is alkyl having 1 to 8 carbon atoms wherein optionally one or more -CH2CH2- groups are replaced in each case by -CH=CH- or -C=C- groups, alkyl having 1 to 8 carbon atoms (optionally substituted), cycloalkyl having 3 to 8 carbon atoms (optionally substituted), a heterocyclic group, which is saturated, partially saturated or fully unsaturated, having 5 to 10 ring atoms in which at least 1 ring atom is a N, O or S atom (optionally substituted), aryl having 6 to 14 carbon atoms (optionally substituted), arylalkyl having 8 to 16 carbon atoms (optionally substituted), a partially unsaturated carbocyclic group having 5 to 14 carbon atoms (optionally substituted), arylalkenyl having 8 to 16 carbon atoms, wherein the alkenyl portion has up to 5 carbon atoms (optionally substituted), a heterocyclic-alkyl group, which is saturated, partially saturated or fully unsaturated, having 5 to 10 ring atoms in which at least 1 ring atom is an N, O or S atom (optionally substituted), or cycloalkylalkyl having 4 to 16 carbon atoms (optionally substituted); R2 is alkyl having 1 to 4 carbon atoms, which is unsubstituted or substituted one or more times by halogen; and R3 is alkyl having 1 to 8 carbon atoms which is substituted one or more times by halogen, oxo, or combinations thereof wherein optionally one or more -CH2CH2- groups are replaced in each case by -CH=CH- or -C=C- groups, cycloalkyl having 3 to 8 carbon atoms (optionally substituted), arylalkyl having 7 to 16 carbon atoms (optionally substituted), heterocyclic-alkyl group, which is saturated, partially saturated or fully unsaturated, having 5 to 10 ring atoms in which at least 1 ring atom is an N, O or S atom (optionally substituted).
Patent NZ-533179-A (NZ)
Title: Hydroxycucurbituril derivatives, their preparation methods and uses
Inventor: KIM KIMOON
IPC: A61K8/72
Filed: 2002-11-26
Abstract: Provided are hydroxycucurbituril derivatives, their preparation methods and uses. The hydroxycucurbituril derivative is easy to further functionalize with enhanced solubility in common solvents, thereby providing wider applications. Provided are hydroxycucurbituril derivatives, their preparation methods and uses. The hydroxycucurbituril derivative is easy to further functionalize with enhanced solubility in common solvents, thereby providing wider applications.
Patent NZ-535912-A (NZ)
Title: Pressurised liquid control valve
Inventor: CRICHTON DAVID GORDON ARTHUR
Filed: 2004-10-14
Abstract: A pressurised liquid control valve 1 comprises a biasing means to bias the valve to a closed mode and an opening means to open the valve the valve to an open mode. An operating weight element 7, which has marginally less than neutral buoyancy, is connected to the opening means by a depending element 8 such that the valve 1 is opened when the full weight of the operating weight causes an opening moment of force. (61) Addition to 535912
Patent NZ-539511-A (NZ)
Title: Dough composition and method of baking yeast-fermented frozen bread products
Inventor: COOPER JOHN
Filed: 2002-10-18
Abstract: Disclosed is a dough composition suitable for baking into yeast-fermented bread products, after freezing, with reduced post freezing fermentation, comprising flour, and the following additional composition components, with percentages based on the weight of the flour contained in the composition: salt 1.8 - 2.3 %, leavening agent 2.5 - 4.5 %, emulsifier 0.01 - 0.5 %, sweetener 0.3 - 2.0 %, L-Cysteine 0.001 - 0.01 %, gluten 0.5 - 4.0 %, oxidant 0.01 - 0.5 %, enzymes 0.01 - 0.5 %, water 50 - 65 % and gum 0.01 - 0.5 %. Also disclosed is a method of making a yeast-fermented bread product from a dough comprising yeast, flour, salt and water, the method comprising blending and mixing the dough; shaping the dough; and allowing the dough to pre-proof for less tban 30 minutes at 26.7 deg C to 37.8 deg C (80 deg F to 100 deg F) and at a relative humidity of at least 70% before freezing the dough; freezing the dough; partially defrosting the dough for a maximum of 60 minutes, with reduced post freezer fermentation prior to bake off, and then baking the partially defrosted dough in a single baking cycle, at a single temperature, leaving the bread product with at least 50% water for increased shelf life, excellent flavor, volume and open internal cell structure.
Patent NZ-545438-A (NZ)
Title: Poxvirus vector encoding prostate specific antigens for treatment of prostate cancer
Inventor: BROWN MICHAEL PAUL
IPC: C07K16/30
Filed: 2004-08-20
Abstract: Provided is a genetic vaccine construct comprising an avipox virus vector which incorporates and, on administration to a subject, expresses in a cell of said subject, a sequence of nucleotides encoding a xenogeneic prostate specific polypeptide or a derivative or analogue thereof, wherein said avipox virus vector does not productively infect said subject. Further provided is a similar construct additionally containing a sequence encoding an immunostimulatory polypeptide. The prostate specific polypeptide can be prostatic acid phosphatase or a derivative or analogue thereof. Also provided are corresponding antibodies and nucleic acid probes and use of the constructs in the manufacture of medicaments.
Patent NZ-545648-A (NZ)
Title: Concentrate for providing essential minerals to animals
Inventor: BELL ALAN RICHARD
Filed: 2006-03-02
Abstract: A stable liquid concentrate for delivering a plurality of essential minerals to an animal, wherein at least one of said essential minerals is iodine, said concentrate comprising the essential minerals in concentrations sufficient that a single dose of the concentrate comprises at least part of the daily requirement of each mineral for the animal. The concentrate additionally comprising at least one essential mineral, wherein the additional essential mineral may be selected from the group consisting of copper, cobalt, zinc and selenium.
Patent NZ-546722-A (NZ)
Title: Fungicidal active combinations spiroxamine, prothioconazole and tebuconazole
Inventor: MAULER-MACHNIK ASTRID
IPC: A01N43/30
Filed: 2004-10-19
Abstract: The disclosure relates to a combination of active substances comprising 8-tert-butyl-1,4-dioxaspiro[4.5]decan-2-ylmethyl(ethyl)(propyl)amine (Spiroxamine), and prothioconazole and tebuconazole. This active combination and which is particularly suitable for combating phytopathogenic fungi.
Patent NZ-548214-A (NZ)
Title: Energy absorbing system using a net that connected through frangible tensioners to raising arms
Inventor: GELFAND MATTHEW A
IPC: E01F13/12
Filed: 2004-11-29
Abstract: An energy absorbing system is disclosed. In use it is able to arrest an errant car (30) and prevent it straying into the path of a train or other obstacle. The energy absorbing system includes a first (300) and second anchor (300), located on opposite sides of a roadway (10). A net (500) is mechanically coupled to each of the anchors (300), spanning the roadway (10). A raising/lowering arm (400) is also arranged on each side of the roadway (10). From each arm (400), an upper and a lower frangible tensioner (450) connects to an upper and a lower portion of the net (500), respectively. During an impact event the frangible tensioners (450) decoupled from the net (50) if a predetermined force is exceeded.
Patent NZ-549198-A (NZ)
Title: Fungal cell wall degrading lysozyme for use as an inhibitor of dental biofilms
Inventor: WU WENPING
IPC: A23K1/165
Filed: 2005-02-16
Abstract: Disclosed is an isolated fungal enzyme having lysozyme activity. Further disclosed is a fungal polypeptide having lysozyme activity and belonging to the GH25 family, wherein the enzyme is selected from the group consisting of (a) a polypeptide comprising an amino acid sequence, which has at least 80% identity with amino acids 1 to 233 of SEQ ID NO:2; (b) a polypeptide comprising an amino acid sequence, which has at least 80% identity with the polypeptide encoded by the lysozyme encoding part of the nucleotide sequence inserted into a plasmid present in strain DSM16084; (c) a polypeptide which is encoded by a nucleotide sequence which hybridizes under high stringency conditions with a polynucleotide probe consisting of the complementary strand of nucleotides 84 to 782 of SEQ ID NO:1; or (d) a fragment of (a), (b) or (c) that has lysozyme activity. Further disclosed is the use of such peptides in the manufacture of a dental composition for inhibiting bio-film formation in a subject.
Patent NZ-556479-A (NZ)
Title: System for producing sterilised aseptic food products by OHMIC heating with post-addition of salted water
Inventor: DOCK GUILLAUME
IPC: A23L23/00
Filed: 2007-07-12
Abstract: Sterilizing a food composition formed from a heterogeneous mixture of at least one liquid phase and solid particles involves preparing a concentrated liquid/particles phase with a reduced amount of salt, a sterilization involving a phase of ohmic heating and a phase of holding the concentrated phase, cooling the sterile concentrated phase and packaging. The concentrated phase is mixed after the heating phase with an aqueous phase comprising sterile salted water for formulation of the heterogeneous mixture of at least one liquid phase and solid particles.; An independent claim is included for an installation for sterilizing the food composition comprising a mixer supplied with a salted sterile aqueous phase and a concentrated liquid/particles phase with a reduced amount of salt, and a sterilizer of the concentrated phase including at least one ohmic heating tube (6a, 6b) and at least one holding tube (8) and a cooling system.
Patent NZ-564127-A (NZ)
Title: Drug delivery systems using dispersions of active powders in cocoa butter or equivalents
Inventor: KANNAR DAVID
IPC: A23G1/30
Filed: 2006-06-02
Abstract: Disclosed is a drug delivery system for a bioactive powder comprising the bioactive powder and a lipid selected from the group consisting of cocoa butter, cocoa butter equivalents, other lipids having a sharp melting curve in the range from 30 to 37 degrees C and which melt in the range from 35 to 37 degrees C, and mixtures thereof, wherein the bioactive powder is dispersed into the lipid and the bioactive powder is substantially evenly dispersed throughout the delivery system, and wherein the drug delivery system is not for use as a suppository.
Patent NZ-567884-A (NZ)
Title: Performing rendering operations to form intermediate data of images, processing the inermediate data, and then performing additional rendering
Inventor: ANDERSON JOHN
IPC: G09G5/00
Filed: 2006-11-22
Abstract: Disclosed is a computer-implemented method for determining high-quality sampling data from low-quality sampling data. The method includes: performing rendering on a number of images of a scene to form intermediate data, the operation in response to scene descriptor data; processing the intermediate data to form a model; determining a higher quality of intermediate data in response to the model; and performing an additional rendering operation to form a further number of images, in response to the higher quality data. At least two images in the initial number of images represent different descriptions of the same scene.
Patent NZ-569790-A (NZ)
Title: Polymorphisms in growth hormone receptor ghrelin, leptin, neuropeptide Y and uncoupling protein 2 genes and their associations with measures of performance and carcass merit in beef cattle
Inventor: MOORE STEPHEN
IPC: G16H70/60
Filed: 2007-01-16
Abstract: Provided is a method for identifying a bovine animal having a higher average daily gain (ADG), a higher final weight (FW), a higher dry matter intake (DMI), a higher metabolic mid-weight (MMW), a higher slaughter weight (SW), a higher loin muscle area (LMA), a higher ultrasound loin muscle area (ULMA), and a higher feed conversion ratio (FeR) as compared to a general population of bovine animals, comprising the steps of: (a) obtaining a biological sample from said bovine animal, wherein the sample comprises nucleic acids comprising the bovine growth hormone receptor (GHR) gene; (b) detecting in said nucleic acids the presence of a single nucleotide polymorphism (SNP) in the GHR gene, wherein the SNP is a G in both alleles of the GHR gene at position corresponding to position 300 of SEQ ID NO:1; and (c) correlating the G in both alleles of the GRR gene to higher FW, DMI, MMW, SW, LMA, ULMA, and FeR, thereby identifying said bovine animal.