baber/WOPTO huggingface dataset:
Patent CA-2439188-A1 (CA)
Title: Mhc-i-restricted presentation of hiv-1 virion antigens without viral replication. application to the stimulation of ctl and vaccination in vivo; analysis of vaccinating composition in vitro
Inventor: HEARD JEAN-MICHEL
IPC: A01N63/00
Filed: 2002-02-26
Abstract: Dendritic cells and macrophages can process extracellular antigens for presentation by MHC-I molecules. HIV-1 epitopes derived from incoming virion s are presented through the exogenous MHC-I pathway in primary human dendritic cells, and to a lower extent in macrophages, leading to cytotoxic T lymphocy te activation in the absence of viral protein neosynthesis. Exogenous antigen presentation required adequate virus-receptor interactions and fusion of vir al and cellular membranes. These results provide new insights about how anti-HI V cytotoxic T lymphocytes can be activated and are useful for anti-HIV vaccine design.
Patent CA-2440443-A1 (CA)
Title: Computer-based strategy for peptide and protein conformational ensemble enumeration and ligand affinity analysis
Inventor: FOX ROBERT O
IPC: C40B30/04
Filed: 2002-03-12
Abstract: The present invention provides a method to generate and analyse ensembles of peptide and protein conformers and predict the affinity of a given conformation of the peptide or protein for a target protein.
Patent CA-2441357-A1 (CA)
Title: Agent for the prevention and treatment of sexually transmitted diseases-i
Inventor: O'KEEFE DAVID FRANCIS
IPC: C08G83/00
Filed: 2002-03-28
Abstract: Use of a polylysine, polyamidoamine or polypropylenimine dendrimer having naphthyl disulphonate terminal groups as a topically applied agent in prophylaxis or treatment of sexually transmitted diseases.
Patent CA-2443665-A1 (CA)
Inventor: CHEYER ADAM
IPC: G06Q30/00
Filed: 2002-04-08
Abstract: A system and method for implementing an open services market platform in a public or private electronic marketplace. The open services market platform (100) includes a layered architecture that accelerates the development and customization of applications in a given marketplace and accommodates integration between multiple marketplaces and /or business partners. The open sevices market platform includes a collaboration layer and a service coordination layer (104). The collaboration layer (102) facilitates multi-party collaboration and provides tools that permit business partners to define relationships among various programming interfaces. The service coordination layer enables business logic to be rapidly customized to meet an organization's evolving needs and facilitates in the selection of an optimal trading partner for a given task. Therefore, electronic marketplaces built with the open services market platform are easily developed and customized to meet the evolving needs of participants within the marketplace.
Patent CA-2443816-A1 (CA)
Inventor: DEWINTER RONNY
IPC: B65D65/46
Filed: 2002-03-05
Abstract: Cette invention concerne un emballage fermé à fibres de renfort (2) composé d'un matériau dégradable en fibres solides. Les fibres de renfort (3) se présentent sous une forme lâche et sont intégrées à l'emballage (2) dans une disposition où elles sont sensiblement parallèles les unes aux autres. L'invention concerne en outre un colis en chapelet (1) constitué de plusieurs emballages fermés (2).
Patent CA-2445608-A1 (CA)
Inventor: GEORGER WILLIAM ANTHONY
IPC: A61F13/534
Filed: 2002-03-04
Abstract: Cette invention se rapporte à un article absorbant tel qu'une mince serviette pour incontinent ou un protège-slip, qui possède un noyau absorbant formé de multiples couches de matériau mélangé pour servir de protection contre les pertes d'urine involontaires. Cette invention décrit également un procédé de formation de cet article absorbant. Cet article absorbant comprend une doublure coté corps perméable aux liquides, une feuille écran imperméable aux liquides et un premier et un second absorbant placés entre la doublure et la feuille écran. Le premier absorbant est constitué par un matériau stabilisé contenant un superabsorbant et il possède un poids de base prédéterminé. Le second absorbant est également constitué par un matériau stabilisé contenant un superabsorbant. Le second absorbant est placé sous le premier absorbant et il possède un poids de base qui est au moins égal au poids de base du premier absorbant.
Patent CA-2446629-A1 (CA)
Inventor: BUTLER MYRON C
IPC: H04M3/30
Filed: 2003-10-24
Abstract: A loop responder enables a telephone technician to use a test device to automatically and accurately validate the performance of a telephone subscriber loop from the originating equipment to the subscriber demarcation point without any human assistance at the central office. The directory number for the subscriber loop under test is automatically identified and stored without any human intervention such that a No Test Trunk can be automatically used and test results can be automatically associated with the respective line record information. Data is collected and then transmitted in suitable manner and stored in non-volatile memory for collection by and/or transmission to a central host processing system.  Particular aspects of the aforementioned collection and storage processes relate to the transmission of the data packets via several input/output (I/O) ports. Either modem or DTMF communication can occur over the same pair of tip and ring wires.
Patent CA-2448526-A1 (CA)
Inventor: JACOBS JEFFREY
IPC: C07D403/12
Filed: 2002-06-14
Abstract: La présente invention concerne le N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl ou hétéroaryl)-azacyclo ¿4-7? alcanes ou thiazacyclo ¿4-7? alcanes ou imidazacyclo ¿4-7 ?alcanes¿ ?présentant des propriétés intéressantes, par exemple dans le traitement ou la prévention de troubles susceptibles d'être traités par des inhibiteurs de la peptidyle déformylase tel que le traitement d'infections bactériennes.
Patent CA-2448900-A1 (CA)
Inventor: MORRIS EDWARD JOSEPH
IPC: A61B17/00
Filed: 2002-06-07
Abstract: The present invention relates to an apparatus and a method for sealing a puncture in a tubular tissue structure or the wall of a body cavity. More specifically, the present invention is directed to an apparatus and method for sealing a puncture site in the wall of a tubular tissue structure, or in the wall of a body cavity with submucosal tissue or another extracellular or matrix-derived tissue capable of remodeling endogenous connective tissue in vivo. The submucosal tissue or another extracellular or matrix-derived tissue is inserted into the puncture site as a sheet (Fig. 1:18) on an introducer element such as a needle (Fig. 1, 17), a cannula (Fig. 1:44), a guide wire (not shown), an introducer element adapted for dialysis (Fig. 1:10), an introducer element adapted for catherization (Fig. 1:10), a trocar (Fig.  1:16), or any other introducer element (Fig. 1:17) used to access the lumen of a tubular tissue structure or used to access a body cavity (Fig. 10A:78).
Patent CA-2449809-A1 (CA)
Inventor: RYAN SHANNON
IPC: G06Q30/02
Filed: 2002-05-16
Abstract: There is provided a method of displaying analytics about a website And its contents resident on a server computer. The method comprises the steps of: (a) causing a browser program to be opened on the server computer with a first display frame and a second display frame immediately adjacent said first display frame, wherein the first display frame comprises a page of the website; (b) marking the page displayed in the first display frame with a first identifier and creating an interface call to a report server; (c) retrieving a report file corresponding to the first identifier from the report server; (d) displaying the analytics in the report file in the second display frame; (e) after a pre-determined period of time, comparing the page displayed in the first display frame with the first identifier; and (f) if different, repeating the method from step (b) for the page displayed in the first display frame; or (g) if the same, resetting for a second of the pre-determined period of time and repeating the method from step (e).
Patent CA-2450407-A1 (CA)
Inventor: FLEISCHMAN SIDNEY D
IPC: A61F2/06
Filed: 2002-07-01
Abstract: Distal anastomosis devices and associated methodology are described herein. Connector (2) and connector components as well as tools associated therewith are disclosed. The connectors (2) are preferably adapted to produce an end-t o- side anastomosis at a graft/coronary artery junction. A fitting (10) alone, or a fitting (10) in combination with a collar (12) may be used as a connector (2). Each fitting (10) may be deployed by deflecting its shape to provide clearance for a rear segment (18) that rotates about adjoining hinge section (s) (28) so to fit the connector within an aperture formed in a host vessel. Upon return to a substantially relaxed position, a rear segment (18) anchors the interfacing with the host vessel/coronary artery. The collar (12) may include features complimentary to those of a fitting (10) and provisions for strain relief and securing the graft vessel.
Patent CA-2450683-A1 (CA)
Inventor: GERMAIN LUCIE
IPC: C12N5/08
Filed: 2002-07-16
Abstract: The tissue-engineered heart valve of the present invention is comprised of elements, such as leaflets, formed from self-supporting human engineered tissue. Such self-supporting tissue is comprised of living biological cells and extracellular matrix without the presence of nonviable scaffolding structures. Thus, the tissue-engineered heart valve of the present invention consists of totally living human tissue which could theoretically function like a native biological structure with the potential to grow, to repair and to remodel.
Patent CA-2451763-A1 (CA)
Title: Process for the recovery of a polyol from an aqueous solution
Inventor: JACKSON JAMES E
IPC: C07C29/88
Filed: 2001-07-19
Abstract: A process for the separation of a polyol or multiple polyols in admixture with other organic compounds, usually those produced with the polyol, is described.  THe process uses a distillation in a column (11) of a cyclic acetal from an aqueous solution which acetal is formed in a reation mixture of the polyol and an aldehyde or ketone. The polyols, such as ethylene glycol and propylene glycol, are staple articles of commerce with many uses.
Patent CA-2452836-A1 (CA)
Title: Meningococcus adhesins nada, app and orf 40
Inventor: COMANDUCCI MAURIZIO
IPC: A61P31/04
Filed: 2002-07-26
Abstract: NadA, App and ORF40 function as adhesins in N.meningitidis. Adhesion can be modulated by targeting these three proteins. NadA allelic variants are disclosed. Autoproteolytic cleavage of App is disclosed, as is removal of the activity by mutagenesis. App is processed and secreted into culture medium when expressed in E.coli. Mature App proteins are disclosed. Knockout mutants are disclosed. Vesicles from non-Neisserial hosts with heterologous adhesin expression are disclosed.
Patent CA-2453418-A1 (CA)
Title: Variolin derivatives and their use as antitumor agents
Inventor: CUEVAS CARMEN
IPC: C07D213/64
Filed: 2002-07-11
Abstract: Variolin derivatives of formula (5) are provided:    (see formula 5) wherein the substituent groups defined by X2, R1, R2, R3, R6, R7 and R12 are each independently selected from the group consisting of H, OH, OR', SH, SR', SOR', SO2R', NO2, NH2, NHR', N(R')2, NHCOR', NHSO2R', CN, halogen, =O, C(=O)H, C(=O)R', CO2H, CO2R', carboxyalkyl, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic;   wherein each of the R' groups is independently selected from the group consisting of H, OH, SH, NO2, NH2, CN, halogen, =O, C(=O)H, C(=O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, aralkyl and heteroaromatic; wherein the pairs of groups R1 and R2, R2 and R3, R3 and R12, R12 and R6, or R6 and R7 may be joined into a carbocyclic or heterocyclic ring system.
Patent CA-2453742-A1 (CA)
Title: Nail clipper for pets with curved blade pieces
Inventor: KUZUU MASAYUKI
IPC: A01K13/00
Filed: 2003-12-19
Abstract: A nail clipper for pets has a scissors structure provided with cutting surfaces formed by curved blade pieces. The curved blade pieces are created by dividing a spherical or elliptical body into quarter pieces having a hollow interior and formed with curved cutting edges. The blade pieces are hinged to opposite ends of a holding piece and moved by pivoting parts coupled to the ends of operating parts of the scissors structure. By operating the scissors structure, the curved blade pieces open and come together to cut the pet's nail, producing smooth nail edges cut in a curved shape with a single cutting action.
Patent CA-2454235-A1 (CA)
Title: Method and apparatus to control delivery of high-voltage and anti-tachy pacing therapy in an implantable medical device
Inventor: PADMANABHAN VASANT
IPC: A61N1/365
Filed: 2002-07-25
Abstract: A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP  therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP during Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP  before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the ATP  therapy is delivered prior to charging of the high-voltage capacitor.  According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP  therapy.
Patent CA-2454615-A1 (CA)
Title: Implant, arrangement comprising an implant, and method for inserting said implant in bone tissue
Inventor: WENDEL MATS
IPC: A61C8/00
Filed: 2002-08-14
Abstract: The present invention relates to a screw implant (1) for insertion into a bore hole (50) arranged in bone tissue, said implant having a cancellous portion (3), and a cortical portion (2) having an axial length such that, when installed in the bore hole (50), the engagement of said cortical portion (2) with the bone tissue will generally be confined to the cortical bone tissue layer (52). Said cortical portion (2) presents an outer surface which is threaded for accomplishing said engagement, and has an outer design such that, when being screwed into said bore hole under action of a screwing torque, said cortical portion (2) acts so as to increase the compression of the cortical bone tissue only, in essentially radial directions of the implant, resulting is a distinct increase of the screwing torque needed for screwing the implant (1). Said increase is usable as an indication that the implant (1) is in place or nearly in place in the bore hole. The invention also relates to an arrangement comprising an implant and a bore hole, and a method for insertion of an implant into a bore hole.
Patent CA-2454870-A1 (CA)
Inventor: FANDELLA SERGIO
IPC: B65G17/40
Filed: 2003-12-30
Abstract: A conveyance chain comprising a plurality of links that are identical and longitudinally associable in succession with a similar one, each link having a head that protrudes at the front of a body supporting a contact plate, to the rear of which two wings protrude, a transverse pivot, made monolithically with the pair of wings and accommodated detachably, in a complementarily shaped slot formed in the head of an adjacent link arranged at the rear, and a bush, arranged by interlocking coupling.
Patent CA-2456427-A1 (CA)
Inventor: CAMARILLO DAVID W
IPC: G06F17/30
Filed: 2004-01-29
Abstract: In an information assistance system, database records are searched for search results that are exact matches or potential matches with the search request. Matches are identified based upon a confidence measure that is generated for each search result. The confidence measure relates to the likelihood that a responsive record contains the information desired by a user. Each search result of an information assistance search output is then sorted and displayed based upon the relative confidence measure of each search result, from, for example, highest confidence measure to lowest. In accordance with an aspect of the invention, a maximum limit and/or minimum limit may be instituted to control the search output. For example, the search output may not be revealed or displayed if the number of search results does not meet the maximum/minimum limit requirement.
Patent CA-2456640-A1 (CA)
Inventor: KOK RONALDUS JOANNES CORNELIS
IPC: B29C45/17
Filed: 2002-08-09
Abstract: This invention provides an arrangement for moving an item from a first station to a transfer tube (50) comprising a transfer tube (50), a transfer arm (26, 28) for placement of the item on the transfer tube, and alignment means for aligning the item with the transfer tube.
Patent CA-2458559-A1 (CA)
Title: Gene d'un nouvel antigene specifique de corynebacterium diphteriae
Inventor: IWAKI MASAAKI
IPC: C12N1/15
Filed: 2002-02-27
Abstract: L'invention concerne un antigène spécifique de Corynebacterium diphteriae servant à développer des vaccins assurant une protection/prophylaxie contre une infection de type diphtérie. L'invention se rapporte en outre à un gène codant pour les protéines (a) ou (b) suivantes : (a) est une protéine comportant la séquence d'acides aminés représentée par SEQ ID NO:1 MFRRSLASLA AVAVISGVVV APANAVTVTV NNMTCTIKLT PEETNFIPLS SPVMLTKEKA AFLKNQYGET QLSALDAEIK KKEKELTELE PNAAGREMLT SELKEKKKRF TANKKFSDAL DACIAGENYD SSKPNGPKDP NGPKKPGDSD QSGGSEKPNG PKDPGGSEKP NDPKHPEVER ALPSTNGAVI GAIVAVLGIL AAAPVIKSI LRALLP, et (b) est une protéine comprenant une séquence d'acides aminés dérivée de la protéine (a) par délétion, substitution, ou addition d'un ou plusieurs acides aminés et présente une activité antigénique dirigée contre Corynebacterium diphteriae.
Patent CA-2461167-A1 (CA)
Title: Integrated barrier and fluid supply for a hospital bed
Inventor: CALDWELL STEVEN
IPC: A61G7/057
Filed: 2002-10-01
Abstract: A patient support apparatus (10) including a barrier (30) coupled to a frame (20). The barrier (30) includes an interior region (128) containing a fluid supply (144). A related method is provided for converting a patient support apparatus (10) to include a fluid filled patient support surface (38).</SDOA B>
Patent CA-2464024-A1 (CA)
Title: Paire de vehicules-jouets maitre et esclave
Inventor: BAUMGARTNER CHRIS T
IPC: A63H30/04
Filed: 2002-10-30
Abstract: La présente invention concerne une combinaison de véhicules-jouets comprenant un véhicule-jouet maître (10, 110) et un véhicule-jouet esclave (20, 120). Le véhicule-jouet maître comprend un émetteur (15, 115) configuré pour émettre un signal de poursuite infrarouge. Le véhicule-jouet esclave comprend au moins un premier et un second récepteur d'infrarouges directionnel (21-24, 174-177) configurés pour recevoir le signal de poursuite du véhicule-jouet maître en provenance de différentes directions autour du véhicule-jouet esclave, et est configuré pour suivre et/ou éviter le véhicule-jouet maître, qui est commandé à distance selon le mode habituel.
Patent CA-2464854-A1 (CA)
Title: Medical device having releasable retainer
Inventor: CAIZZA RICHARD J
IPC: A61M5/34
Filed: 2004-04-23
Abstract: A medical device having a releasable retaining includes needle cannula connected to a hub having an open proximal end with a frusto-conically shaped cavity therein. The cavity is part of a passageway through the hub which is in fluid communication with the lumen of the needle cannula. A retaining element is releasably connected to the hub. The hub includes an aperture and at least one protuberance projecting into the aperture for engaging the frusto-conically shaped tip of a fluid delivery device. The protuberance is shaped to offer less resistance to hub movement in a direction of engagement than in a direction of disengagement with the tip. The retaining element is connected to the hub so that when the hub is engaged to the tip, the force required to disengage the retaining clement from the tip is greater than the force required to disengage the retaining element from the hub.
Patent CA-2465876-A1 (CA)
Title: System and method for propagating data
Inventor: OVERTURF JOHN D
IPC: H04L29/08
Filed: 2004-04-30
Abstract: A system and method for propagating data commutates data from different data sources into a data stream based on a commutation format. The data is received and decommutated to replicate the data. The commutation format can be changed for prioritizing different data from the data sources.
Patent CA-2467067-A1 (CA)
Inventor: MAKOFKA DOUGLAS S
IPC: H04N21/472
Filed: 2002-11-14
Abstract: A method for distributing a content object over a network system is disclosed.  In one step, a request is detected for the content object associated with one of a plurality of content providers (Fig.1A/108, 112) coupled to a network (122) that uses a first transport protocol. A node of the network (Fig.2A/208-3) receives the content object from the one of the plurality of content providers (108, 112). The content object is buffered at a point distant from the one of the plurality of content providers and the content receiver (Fig.2A/206-4). The content object is transported between the node and a content receiver with a second transport protocol. The first transport protocol is different from the second transport protocol.
Patent CA-2468465-A1 (CA)
Title: Centrifugal turbine for breathing-aid devices
Inventor: LIEGEOIS PASCAL
IPC: F04D17/06
Filed: 2002-11-08
Abstract: The invention concerns an electric turbine (1) comprising a turbine rotor (4, 7), a turbine stator (2, 3), an electric motor member (5, 6) for driving the rotor (4, 7) in rotation relative to the stator (2, 3), and having the following features: the turbine stator (2, 3) comprises a stator body defining a compression chamber (12); the turbine rotor (4, 7) includes a plurality of blades (26, 27) integral with a shaft (4) mounted coaxially rotating in the body (2, 3) of the turbine stator; the electric motor member (5, 6) comprises a toroidal motor stator (6) housed in a motor housing (16, 23) of the turbine stator (2, 3), at the center of the toroidal compression chamber (12) and a motor rotor (5) mounted on the shaft (4) of the turbine rotor, axially opposite the motor stator (6).
Patent CA-2470488-A1 (CA)
Title: Chair back for a chair
Inventor: HARLEY ALEXANDER
IPC: A47C7/42
Filed: 2004-06-07
Abstract: A chair back for a chair that includes a support frame portion having a defined shape and is adapted to attach to a chair base member. The chair back for a chair may also include a tensioning frame portion having a defined shape and a removable elastomeric support sleeve having an opening adapted to receive the defined shape of the support frame portion and the defined shape of the tensioning frame portion. The removable elastomeric support sleeve may be slid first over the support frame portion so as to conform the removable elastomeric support sleeve to the defined shape of the support frame portion. The removable elastomeric support sleeve may then be slid second over the tensioning frame portion thereby conforming the elastomeric support sleeve to the defined shape of the tensioning frame portion. The support frame portion may be adapted to receive and secure the tensioning frame portion, so that the force of connecting the tensioning portion to the support frame portion locks the defined shape of the support frame portion and the defined shape of the tensioning frame portion to one another along with the removable elastomeric support sleeve and therefore forms the chair back.