baber/WOPTO huggingface dataset:
Patent WO-2022182954-A1 (WO)
Inventor: POTTER HUNTINGTON
IPC: A61K38/17
Filed: 2022-02-25
Abstract: Des modes de réalisation de la présente invention concernent de nouvelles méthodes de traitement d'une ou de plusieurs entités pathologiques du diabète de Type 2. Dans certains modes de réalisation, des méthodes concernent la réduction du risque de développement, la prévention et/ou le traitement d'une entité pathologique du diabète de Type 2 ou d'une autre affection ayant un composant d'entité pathologique par l'administration à un sujet qui en a besoin d'un facteur de stimulation de colonies de granulocytes-macrophages (GM-CSF) ou d'une molécule produite par recombinaison ou d'un fragment associé, ou d'un analogue associé. Dans d'autres modes de réalisation, des méthodes concernent la diminution du dépôt d'amyloïde des îlots pancréatiques chez un sujet par l'administration au sujet, de GM-CSF ou d'une molécule produite par recombinaison ou d'un fragment associé, ou d'un analogue associé, le sujet ayant un dépôt d'amyloïde des îlots pancréatiques.
Patent WO-2022204070-A1 (WO)
Title: Methods of determining potency of a therapeutic cell composition
Inventor: HAIG NEIL
IPC: G01N33/50
Filed: 2022-03-21
Abstract: The present disclosure relates to methods of determining potency of a therapeutic cell compositions in connection with cell therapy. The cells of the therapeutic cell composition can express recombinant receptors such as chimeric receptors, e.g., chimeric antigen receptors (CARs) or other transgenic receptors such as T cell receptors (TCRs). The methods provide an assay for identifying the potency, including relative potency, of a therapeutic cell composition.
Patent WO-2022217068-A1 (WO)
Title: Methods of treatment for leukemia
Inventor: SOWADSKI JANUSZ
IPC: A61P35/02
Filed: 2022-04-08
Abstract: Provided herein are methods of use a cyclin dependent kinase (CDK) inhibitor for the treatment of leukemia. The CDK inhibitor described herein include NU6027. The methods described herein include methods of treatment of drug-resistant leukemia, such as leukemia presenting ABL1 mutations and chronic myelogenous leukemia (CML) comprising the administration of NU6027.
Patent WO-2022226010-A1 (WO)
Title: Molybdenum(0) precursors for deposition of molybdenum films
Inventor: BARIK CHANDAN KR
IPC: C07F11/00
Filed: 2022-04-20
Abstract: Molybdenum(0) and coordination complexes are described. Methods for depositing molybdenum-containing films on a substrate are described. The substrate is exposed to a molybdenum precursor and a reactant to form the molybdenum-containing film (e.g., elemental molybdenum, molybdenum oxide, molybdenum carbide, molybdenum silicide, molybdenum disulfide, molybdenum nitride). The exposures can be sequential or simultaneous.
Patent WO-2022226252-A1 (WO)
Title: Hydrophilic poly(thioketal) urethane scaffolds and methods of use thereof
Inventor: DUVALL CRAIG L
IPC: A61L27/18
Filed: 2022-04-21
Abstract: The presently-disclosed subject matter includes hydrophilic thioketal polymers and scaffolds formed therefrom.
Patent WO-2022232399-A1 (WO)
Inventor: FLEURY SEAN P
IPC: A61B17/12
Filed: 2022-04-28
Abstract: L'invention concerne un dispositif implantable capable de réguler l'écoulement de matériau à travers un passage corporel. Le dispositif implantable peut comprendre au moins un élément de retenue ayant une surface incurvée pour résister à la migration du dispositif implantable par rapport au passage corporel. Le dispositif implantable peut être pourvu de caractéristiques fournissant un effet d'amortissement par rapport au tissu au niveau duquel le dispositif implantable est implanté. La longueur du dispositif implantable et/ou la configuration d'au moins un élément de retenue sur le dispositif implantable sont ajustables. Un élément de retrait peut être fourni pour faciliter le retrait du dispositif implantable.
Patent WO-2022245890-A1 (WO)
Inventor: GILDEA THOMAS
IPC: A61F2/04
Filed: 2022-05-18
Abstract: A bronchial stent includes a first branch configured to widen, open, and/or mechanically support a first airway; an obstructive portion that, when the stent is deployed in the first airway, obstructs a second airway, the second airway forming a branching connection with the first airway; and a feature proximal to the obstructive portion, the feature configured to facilitate opening of the obstructive portion.
Patent WO-2022246192-A1 (WO)
Title: Low-cost miniaturized vertical coaxial cable to pcb transition for use in ultra-dense base station antennas
Inventor: VAKIL VANKAR
IPC: H01R103/00
Filed: 2022-05-20
Abstract: Disclosed is a vertical RF launch mechanism for installing an RF cable onto an antenna PCB. The mechanism includes a cutout formed in the PCB whereby the cutout has interlocking tabs and an inner conductor receptacle formed in one interior edge. Installed on this interior edge is a vertical clip that has two tabs and a cylindrical outer conductor receptacle. The design of the cutout and the clip allows an RF cable to be installed so that it is vertically mounted to the PCB, provides a high-quality coupling for both the inner and outer conductors of the RF cables. It enables the soldering for both the inner and outer conductors to be done from the same side of the PCB. It also provides for a smaller cutout relative to conventional RF PCB launches, enabling a higher density placement of RF cable launches on a given PCB, providing for ultra-dense antenna designs.
Patent WO-2022271673-A1 (WO)
Inventor: PIUCCI VINCENT
IPC: A61M16/00
Filed: 2022-06-21
Abstract: Embodiments of the innovation relate to a ventilator, comprising: a positive displacement pump having a drive motor and configured to output a predetermined volume of inspiratory gas for each rotation of an output shaft of the drive motor; at least one pressure sensor configured to measure inspiratory pressure; and a control unit having a controller comprising a memory and a processor, the control unit disposed in electrical communication with the drive motor and with the at least one pressure sensor. The controller is configured to: receive at least one of an operation signal and a pressure sensor signal, and transmit a drive motor control signal to the drive motor to adjust at least one of a rotational speed of the output shaft and a number of rotations of the output shaft based upon the at least one of the operation signal and the pressure sensor signal.
Patent WO-2023278700-A1 (WO)
Title: Compositions and methods for styling hair
Inventor: SHAH VIBHA K
IPC: A61K8/34
Filed: 2022-06-30
Abstract: The disclosure relates to compositions comprising (a) at least one polyphenol; (b) at least one film former; (c) at least one emulsifier; (d) at least one fatty compound; and (e) at least one solvent. Optionally, the compositions may further comprise at least one oil, at least one humectant, and/or at least one fatty acid. The compositions can be used for styling hair, for example temporarily straightening the hair and/or for reducing frizz of hair. The disclosure also relates to methods of using the compositions to style hair, straighten hair, and/or reduce frizz of hair.
Patent WO-2022272184-A1 (WO)
Inventor: BANERJEE ARIJIT
IPC: G11C11/412
Filed: 2022-07-08
Abstract: An apparatus and method for providing efficient floor planning, power, and performance tradeoffs of memory accesses. Adjacent bit cells in a column of an array use a split read port such that the bit cells do not share a read bit line while sharing a write bit line. The adjacent bit cells include asymmetrical read access circuits that convey data stored by latch circuitry of a corresponding bit cell to a corresponding read bit line. The layout of adjacent bit cells provides a number of contacted gate pitches per bit cell that is less than a sum of the maximum number of metal gates in layout of each of the adjacent bit cells divided by the number of adjacent bit cells.
Patent WO-2023004049-A1 (WO)
Inventor: CHANG WEN-HSUAN
IPC: C12N15/113
Filed: 2022-07-21
Abstract: La présente invention concerne des oligonucléotides antisens d'exon cryptique UNCI 3 A (ASO), des compositions pharmaceutiques les contenant, et des procédés de traitement, d'inhibition, de suppression et de prévention de maladies neurologiques à l'aide de ceux-ci.
Patent WO-2024025528-A1 (WO)
Title: Plateforme de négociation intégrant un teneur de marché automatisé et un livre de commandes
Inventor: LARIMER DANIEL J
IPC: G06Q40/04
Filed: 2022-07-27
Abstract: Des modes de réalisation concernent une plateforme de négociation avec une infrastructure informatique distribuée. Un système et un procédé de négociation d'actifs numériques qui impliquent l'intégration d'un livre de commandes hybride, d'un moteur de mise en correspondance, d'un gestionnaire de marché automatisé et d'un service de prêt de marge sûre.
Patent WO-2023028105-A1 (WO)
Inventor: HIPSLEY ANNMARIE
IPC: G16H80/00
Filed: 2022-08-24
Abstract: L'invention concerne un système pour un assistant à distance intégré virtuel. Dans certains modes de réalisation, le système réalise des opérations consistant à recevoir une entrée pour une intervention chirurgicale. Les opérations comprennent en outre la détermination d'une première rétroaction pour la procédure chirurgicale. Les opérations comprennent en outre la réception, en réponse à la première rétroaction, d'une entrée d'utilisateur. Les opérations comprennent en outre la réception d'une seconde rétroaction à partir d'un appareil laser. Les opérations comprennent en outre la réalisation d'une vérification de l'oculométrie pour un utilisateur. Les opérations comprennent en outre l'affichage d'un affichage graphique d'un assistant virtuel. Des systèmes, procédés et articles manufacturés associés sont également décrits.
Patent WO-2023069439-A1 (WO)
Title: Bathtub toy and methods of using the same
Inventor: WESTERHAUS MARY
IPC: A47K5/08
Filed: 2022-10-18
Abstract: A bathtub toy apparatus comprises a housing having a space therein for a fizzing bath bomb sphere, puck, or other shape. The housing comprises an entrance aperture configured to allow entry of water into the housing. Embodiments of the present invention further provide an exit aperture for expelling fizz generated by the fizzing bath bomb sphere or puck. Other embodiments incorporate transparent or translucent panels therein for viewing the fizz generated by the fizzing bath bomb sphere or puck. Methods of using the same are further provided.
Patent WO-2023069688-A1 (WO)
Title: Uplink timing adjusment in high speed deployments
Inventor: BOLOTIN ILYA
IPC: H04W72/04
Filed: 2022-10-21
Abstract: An apparatus and system of uplink timing adjustment for frequency range 2 (FR2) communication with remote radio heads (RRHs) in a unidirectional high speed train (HST) deployment are described. A one-shot uplink timing adjustment is applied when a first value is greater than a second value. The first value is a difference between an end of a first transmission from a neighboring RRH and an end of reception of the first transmission at the UE less a difference between an end of a second transmission from a serving RRH and an end of reception of the second transmission at the UE. The second value is a predetermined gradual timing adjustment set by a 3GPP specification, the predetermined adjustment plus a timing error limit, the predetermined adjustment plus twice a downlink error, or a multiple of the predetermined adjustment. The one-shot uplink timing adjustment is twice the first value.
Patent WO-2023076197-A1 (WO)
Title: Circuit et procédé de polarisation d'un amplificateur
Inventor: KOPPASSERY GIRISH
IPC: H03F1/22
Filed: 2022-10-25
Abstract: La présente divulgation concerne un circuit amplificateur (300) qui comprend un cœur d'amplificateur (360) ayant un transistor cascode (372) et un transistor de gain (374), un circuit de polarisation (310) couplé au cœur d'amplificateur (360), le circuit de polarisation (310) comprenant : une première source de courant (312), une deuxième source de courant (328), un amplificateur opérationnel de transconductance (338), une paire de transistors cascode de polarisation ayant un transistor cascode de polarisation (342) et un transistor de gain de polarisation (346), et un circuit de réplique (355) couplé à la première source de courant (312) et à la deuxième source de courant (328).
Patent WO-2023081287-A1 (WO)
Title: Clamp with movement management
Inventor: SMITH ROBIN
IPC: B25B5/06
Filed: 2022-11-03
Abstract: A clamp includes a bar having top and bottom surfaces, a fixed jaw fixed to the bar, and a movable assembly movable along the bar. The movable assembly includes a movable jaw, an actuator that incrementally moves the movable assembly to apply a clamp force to a clamp load, a release lever to disengage the movable assembly to release a clamp force and permit free sliding of the movable assembly along the bar. The movable assembly may support a bearing surface formed of a low-friction material, positioned to prevent the movable assembly from binding to the bar when a clamp load is released. The release lever may be movable between a position engaging the bar, a position where the release lever disengages the bar, and another position engaging the bar, the third position being opposite the first position with the second position therebetween.
Patent WO-2023107270-A1 (WO)
Inventor: AGARWAL PRAVEEN
IPC: C08G18/80
Filed: 2022-11-21
Abstract: The present invention provides blocked isocyanate prepolymers comprising, in copolymerized form, one or more C8 to C24 hydrocarbyl group-containing phenol blocking agents, such as a cardanol, and one or more monohydric alcohols having a normal boiling point of 110 °C or higher, such as an alkoxypoly(alkylene glycol), for example, a methoxy poly(ethylene glycol). The blocked isocyanate prepolymers exhibit a surprisingly improved storage stability. In addition, the present invention provides methods of making the blocked isocyanate prepolymers comprising reacting a polyol with a molar excess of a polyisocyanate, blocking the resulting prepolymer and then adding the monohydric alcohol under conditions to react the prepolymer and the monohydric alcohol, such as at a temperature of from 60 to 100 °C.
Patent WO-2023129359-A1 (WO)
Inventor: TYAGI VIPIN
IPC: C25D17/10
Filed: 2022-12-10
Abstract: Disclosed herein is an electrolyzer comprising a horizontal cathode located below a suspended anode for purposes of performing electrolysis on metal-bearing mixtures or solutions. The horizontal cathode may comprise the bottom surface of a compartment for containing a mixture or solution of metal components, electrolyte, and/or supplemental chemicals. The horizontal anode may engage the upper surface of the mixture or solution in the compartment. A removal mechanism for facilitating removal of the end-products of the mixture or solution from the compartment (and the surface of the horizontal cathode) through the gate may also be employed. These implementations may be used in recycling of lead acid batteries (LABs) without any need for smelting, and also may be applied to a variety of different electrolytical operations.
Patent WO-2023114286-A1 (WO)
Inventor: KACIK MARK
IPC: F16L17/03
Filed: 2022-12-14
Abstract: L'invention concerne un appareil à tuyau pouvant comprendre un dispositif de couplage avec un joint d'étanchéité entourant un axe central. Le joint d'étanchéité comprend en outre une première poche circonférentielle au moins partiellement définie par une première et une seconde bride circonférentielle. Un dispositif de guidage de fluide positionné au moins partiellement à l'intérieur de la première poche circonférentielle comprend une pluralité de segments qui sont agencés radialement de manière à entourer l'axe central. Le dispositif de guidage de fluide définit au moins partiellement un trajet de fluide. Les procédés peuvent comprendre l'utilisation du dispositif de couplage pour coupler une première partie d'extrémité d'un premier segment de tuyau à une seconde partie d'extrémité d'un second segment de tuyau. Les procédés d'utilisation de l'appareil à tuyau peuvent comprendre le passage d'un fluide à travers le trajet de fluide pour refroidir le joint d'étanchéité.
Patent WO-2023122131-A1 (WO)
Inventor: MA LIANG
IPC: G01S13/86
Filed: 2022-12-21
Abstract: L'invention concerne un système de surveillance par caméra comprenant un premier ensemble de remplacement de miroir comportant un boîtier supportant une caméra orientée vers l'arrière (20a) et un capteur de distance orienté vers l'arrière (50), un dispositif de commande en communication avec l'ensemble de remplacement de miroir, le dispositif de commande comportant un processeur et une mémoire, la mémoire stockant des instructions pour identifier au moins un objet dans un flux d'images provenant de la caméra et pour déterminer une position angulaire de l'objet à l'aide d'une analyse d'images, et pour identifier une distance entre le ou les objets et l'ensemble de remplacement de miroir à l'aide du capteur de distance ; et la fusion de la distance et de la position angulaire de l'objet en un seul ensemble de données, et un écran (18a) connecté au dispositif de commande et configuré pour afficher une vue de remplacement du miroir comprenant au moins une partie du flux d'images.
Patent WO-2022192861-A1 (WO)
Title: Methods and systems for operational surveillance of a physical asset using smart event detection
Inventor: RUSSENES CARSTEN FALCK
IPC: G06F16/906
Filed: 2022-03-08
Abstract: Methods and systems are provided for monitoring a physical asset, which includes receiving or collecting time-series data related to operation or status of the physical asset; identifying a time period when the physical asset is experiencing a change in operational state; extracting time-series data corresponding to the time period as event data; generating label data that classifies or characterizes the event data as pertaining to a particular type of event; saving the event data and the corresponding label data in a data repository; and using the event data and label data stored in the data repository to train or update a machine learning system to detect the occurrence of events that are similar to the event types of the labeled event data stored in the data repository from time-series data generated by the physical asset or by another physical asset that operates in a similar manner to the physical asset.
Patent WO-2022261632-A1 (WO)
Title: Bone biopsy device and related methods
Inventor: RAGSDALE CLARK
IPC: A61B10/02
Filed: 2022-06-07
Abstract: Devices and methods used to obtain core tissue samples are disclosed. The devices may be configured to drill into cortical bone and saw a hole into a bone lesion and/or bone marrow while obtaining the core tissue sample. The devices can include a motor and a clutch configured to rotate a trocar having a tip configured for drilling and an outer coax cannula having a trephine tip configured for sawing. The core tissue sample may be received within an inner cannula as an intermediate cannula cuts a hole in the bone lesion and/or bone marrow. The devices can include a spacer.
Patent WO-2023283580-A1 (WO)
Title: In situ catalyst deposition and utilization
Inventor: DAUGHERTY MARK
IPC: C25B15/00
Filed: 2022-07-06
Abstract: Disclosed herein is an electrolyte comprising OH - and a hydrogen evolution electrocatalyst, an oxygen evolution electrocatalyst, a bifunctional hydrogen/oxygen evolution electrocatalyst, or any combination thereof for use in in situ deposition or utilization. Also disclosed is a separator electrode assembly, upon which the electrocatalyst will be deposited to maintain a high reactor efficiency.
Patent WO-2023086699-A1 (WO)
Title: Report de sps harq-ack avec des priorités différentes
Inventor: HUANG YI
IPC: H04L1/18
Filed: 2022-09-16
Abstract: La présente divulgation concerne des systèmes, des procédés et un appareil, incluant des programmes informatiques codés sur des supports de stockage informatiques pour résoudre des collisions entre des transmissions en liaison montante reportées sur la base de la priorité. Un équipement utilisateur (UE) reçoit une première configuration de planification semi-persistante (SPS) incluant une indication de ressources pour un rapport d'accusé de réception (ACK) en tant qu'informations de commande de liaison montante (UCI), la première configuration de SPS indiquant un premier niveau de priorité. L'UE reçoit une seconde signalisation indiquant un second niveau de priorité pour une seconde transmission, le second niveau de priorité étant supérieur au premier niveau de priorité. L'UE reporte une première transmission d'UCI selon la première configuration de SPS pendant un ou plusieurs créneaux de liaison descendante vers un premier créneau apte à la liaison montante. La première transmission d'UCI dans le premier créneau apte à la liaison montante entre en collision avec la seconde transmission. L'UE transmet la seconde transmission dans le premier créneau apte à la liaison montante sur la base du second niveau de priorité qui est supérieur au premier niveau de priorité.
Patent WO-2023049883-A1 (WO)
Title: Systems or devices and methods for managing thermocouple service life
Inventor: YOUEL NATHAN
IPC: G01K1/08
Filed: 2022-09-26
Abstract: The present disclosure is directed to a thermocouple management device for monitoring a preset service life of at least one thermocouple and methods of use. The device may include: a housing; at least one terminal disposed on the housing configured to receive, from at least one thermocouple, a temperature measurement of a material; at least one interface component disposed on the housing configured to receive and adjust a time period associated with the preset service life of the at least one thermocouple; at least one indicator disposed on the housing; and a timing component disposed within the housing, wherein the timing component is configured to: instantiate a timer upon installation of the at least one thermocouple; and upon expiration of the timer, trip at least one relay to disable the at least one thermocouple.
Patent WO-2023081720-A1 (WO)
Inventor: STUART IAIN
IPC: A61K31/437
Filed: 2022-11-02
Abstract: La présente invention concerne des procédés de traitement, de soulagement, ou de prophylaxie d'une maladie ou d'un trouble inflammatoire et/ou auto-immun ou d'une maladie ou d'un trouble lié à celui-ci (par exemple, de lésions, de maladies et de troubles pigementaires ou liés à la pigmentation, de maladies et de troubles articulaires ou liés aux articulations, de maladies ou de troubles respiratoires ou associés aux voies respiratoires ; et les maladies et troubles de fibrose ou associés à la fibrose) à l'aide d'inhibiteurs de BET doux.
Patent WO-2023091919-A1 (WO)
Inventor: WANG CHAO
IPC: C08G18/28
Filed: 2022-11-16
Abstract: L'invention concerne une composition adhésive thermofusible réactive comprenant le produit de réaction de 5 % en poids à 40 % en poids d'un premier polyester polyol comprenant le produit de réaction d'un monomère d'acide dicarboxylique, d'un tétra-alkylcyclobutane diol et éventuellement d'un ou de plusieurs monomères supplémentaires, de 10 % en poids à 80 % en poids d'un polyol durable et un diisocyanate.
Patent WO-2023092123-A1 (WO)
Title: Hyperspectral imaging of moving microscopic sample elements
Inventor: BEACH JAMES MELVIN
IPC: G01J3/32
Filed: 2022-11-21
Abstract: Various examples are provided related to hyperspectral imaging of moving microscopic sample elements. In one example, a method for hyperspectral imaging includes acquiring a series of optical images and corresponding hyperspectral data of a sample; compiling a movie comprising a series of frames each including one of the series of optical images and a slit line indicating a location of a slit for acquisition of the hyperspectral data; identifying a frame comprising an element of the sample located on the slit line; and analyzing the hyperspectral data corresponding to the optical image in the identified frame. Each optical image and its corresponding hyperspectral data are acquired simultaneously and identified by a time stamp or sequence number. The analysis can generate hyperspectral information about the element. In another example, a system for hyperspectral imaging includes a hyperspectral imaging device; an optical imaging device; and a computing device.