baber/WOPTO huggingface dataset:
Patent DE-69332782-T2 (DE)
Inventor: AMIDON GORDON L
IPC: A61K9/48
Filed: 1993-04-20
Granted: 2003-12-18
Abstract: A drug delivery system (10) includes a first capsule half (12) having an inner chamber (16) for containing a drug (18) therein. A plug (28) is disposed in a passageway (26) of the capsule half (12) for plugging the opening (24) thereof. The plug (28) is releasable from the passageway opening (24) upon the application of pressure from within the inner chamber (16).  A pump mechanism, reactive with the external environment of the capsule half (12), causes an increase in pressure within the inner chamber (16) and forces the plug (28) out of the passageway (26) to release the drug (18) from the inner chamber (16) and out of the passageway (26). Thusly, after initial release of drug from a second capsule half (14) releasably mounted on the first capsule half (12), the first capsule half (12) provides a second pulse of drug release at a predetermined time after initial ingestion of the capsule. The invention further provides a method of manufacturing the drug delivery system (10) and method by which the drug delivery system (10) provides the drug to a body.
Patent DE-69333885-T2 (DE)
Inventor: HORUK RICHARD
IPC: A61K38/00
Filed: 1993-11-04
Granted: 2006-09-14
Abstract: DNA isolates encoding the human C-C chemokine receptor C-C CKR-1 and methods of obtaining such DNA are provided, together with expression systems for recombinant production of C-C CKR-1 useful in therapeutic or diagnostic compositions. Additionally, a method for identifying new chemokine receptors is provided.
Patent DE-69407192-T2 (DE)
Inventor: DE BOER ERIC
IPC: C08F4/639
Filed: 1994-07-29
Granted: 1998-03-26
Abstract: Use of a heterocyclopentadienyl of the general formula    C4AR4,   wherein A is a Group 15 element and each R, which is connected to a carbon of the cyclodienide ring, can be the same or different and is chosen from hydrogen or an organic substituent (optionally containing one or more hetero-atoms),  in complex with a Group 4 or 5 metal, in a catalyst composition for the (co)oligomerisation or (co)polymerisation of olefinically unsaturated hydrocarbons, Group 4 and 5 metal complexes comprising such heterocyclopentadienyl, catalyst compositions comprising such organometal complexes and the process of (co)oligomerisation or (co)polymerisation olefinically unsaturated hydrocarbons in the presence of such catalyst compositions.
Patent DE-69409385-T2 (DE)
Inventor: VANDEMOORTELE PHILIPPE
IPC: A61F5/44
Filed: 1994-07-08
Granted: 1998-07-23
Abstract: PCT No. PCT/FR94/00857 Sec. 371 Date Jan. 5, 1996 Sec. 102(e) Date Jan. 5, 1996 PCT Filed Jul. 8, 1994 PCT Pub. No. WO95/02381 PCT Pub. Date Jan. 26, 1995An absorbent article of hygiene with a double leakproofing barrier of simple and economical manufacture includes two side flaps (11) secured together at their transverse ends and a lengthwise fold (16) pointing vertically towards the interior, to form an oblong central opening (17) about the absorbent pad (2) which constitutes a peripheral first leakproofing barrier, the two vertical folds themselves constituting a side second leakproofing barrier.
Patent DE-69419750-T2 (DE)
Inventor: WILLEY ALAN
IPC: D06L1/20
Filed: 1994-05-12
Granted: 2000-05-31
Abstract: The present invention relates to a method of cleaning fabrics in washing machines which have parts made of natural rubber using laundry detergents comprising N-acyl caprolactam bleaching activators and a source of hydrogen peroxide such that said natural rubber parts of said machines are substantially undamaged by free radical by-products of the perhydrolysis reaction between the activator and hydrogen peroxide.
Patent DE-69505097-T2 (DE)
Inventor: LAVIEVILLE JEAN-PAUL
IPC: H02M7/483
Filed: 1995-12-28
Granted: 1999-04-08
Abstract: The multilevel convertor includes capacitors (C1,C2...,Cn) for each of its cells. The capacitors have nominally charge voltages proportional to their row in the convertor. The convertor also includes devices (VMO1,VMO2...,VMOn) designed to evaluate the average voltage at the terminals of each of the capacitors (C1,C2...,Cn), and devices (VE1,VE2...,VEn) for monitoring, for each of the capacitors (C1,C2...,Cn), the eventual difference between the evaluated average charge voltage and the nominal average voltage of the capacitor, and to provide a corresponding difference signal (VEC1,VEC2...,VECn). The convertor also has correction control devices (BT,EC1,EC2...,ECn), receiving the difference signal and controlling as a consequence, a temporary coupling between two capacitors, with the aim of reducing the voltage difference.
Patent DE-69508390-T2 (DE)
Inventor: RANDALL CATHERINE
IPC: A61F13/15
Filed: 1995-04-10
Granted: 1999-08-26
Abstract: An absorbent article, such as a sanitary napkin, having flaps and zones of differential extensibility for relieving the stresses that develop in the flaps when the flaps are folded down along the edges of crotch of the wearer's undergarments is provided.
Patent DE-69512158-T2 (DE)
Inventor: NICOLAS JACQUES
IPC: F42B12/20
Filed: 1995-07-07
Granted: 2000-01-20
Abstract: An explosive projectile (1) of medium calibre, which comprises a generator explosive body (2) in which are distributed an explosive and/or incendiary charge (7) initiated by means of a primer (4). The device also comprises an intermediate charge (9) situated between the primer (4) and explosive charge (7) consisting of a mixt. of an explosive and a prim. pyrotechnic compsn. consisting of the association of at least one oxidant and one reducing agent. <IMAGE>
Patent DE-69512940-T2 (DE)
Inventor: ANDO AKEMI
IPC: A61K31/42
Filed: 1995-06-07
Granted: 2000-02-17
Abstract: PCT No. PCT/JP95/01127 Sec. 371 Date Nov. 5, 1997 Sec. 102(e) Date Nov. 5, 1997 PCT Filed Jun. 7, 1995 PCT Pub. No. WO96/40659 PCT Pub. Date Dec. 19, 1996Described herein are N-hydroxyurea compounds having the ability to inhibit the 5-lipoxygenase enzyme and having formula (I) and the pharmaceutically acceptable salts thereof. The variables are described herein. These compounds are useful in the treatment or alleviation of inflammatory diseases, allergy and cardiovascular diseases in mammals and as the active ingredient in pharmaceutical compositions for treating such conditions.    <IMAGE>  (I)
Patent DE-69513381-T2 (DE)
Inventor: HECK RICHARD
IPC: B07C5/34
Filed: 1995-09-06
Granted: 2000-06-15
Abstract: The topographic surface features of a translucent object, such as a citrus fruit with a peel, are scanned and evaluated to permit the classification thereof according to its surface features. In the case of citrus fruit, the coarseness or pebbliness, puff and crease, ridge and valley, cuts, punctures, scrapes and splits, clear rot or sour rot of the peel is optically identified through digital analysis of the pixel scans and sorted based upon the peel surface quality. The object is classified by separating the scanned image of the fruit from the background image and removing the background image. A statistical evaluation of the image of the object as a whole, including both hemispheres of the object, is made to determine if there is any surface feature variation which might qualify as a defect or be a suitable basis upon which a classification judgment can be made. If there is, the object image is subject to high frequency or low pass filtering and thresholding of the pixel intensities to derive a refined image. The refined image is then tabulated or organized into neighborhoods contiguous to sharp transitions or gradual transitions to identify specific areas defined as blobs which, when compared against a given minimum area, shape requirement and/or width can be identified as one of the surface imperfections sought.
Patent DE-69527867-T2 (DE)
Inventor: PATARIN JACQUES
IPC: G06Q20/40
Filed: 1995-03-09
Granted: 2003-02-13
Abstract: The system uses an electronic card (1), a central computer (4) and a sales point terminal (8). The electronic card (1) carries a card number (Ns) and an authentication value (VA). The central computer (4) has processing circuits (5) and memory (6) containing a cryptographic disymmetric algorithm (F) and secret key (Ks). The sales point terminal (8) contains processing circuits (9) and a memory (10) which stores an inverse algorithm (G) and public key (Kp). The authentification value (VA) is intially found by the central computer and placed on the card and in subsequent transactions the card number (Ns) and user information (I) are checked by the sales terminal using the inverse algorithm and public key (Kp).
Patent DE-69532894-T2 (DE)
Inventor: SPICER DARCY V
IPC: A61P15/18
Filed: 1995-11-21
Granted: 2004-09-02
Abstract: Compositions and methods for use in treating benign gynecological disorders, wherein an effective amount of an antiprogestational agent Äe.g., progesterone (progestin, progestogen, gestagen) antagonist or progesterone synthesis inhibitorÜ administered over a first period of time is combined with an effective amount of a progestogen for a second period of time. The antiprogestational agent is selected from single agents or mixture thereof. The progestogen is selected from single agents or mixtures of natural or synthetic progestogens. The formulations are effective as contraceptive agents and for treatment of benign gynecological disorders including uterine fibroids, premestrual syndrome, dysfunctional uterine bleeding, polycystic ovarian syndrome and endometriosis.
Patent DE-69534351-T2 (DE)
Inventor: MELKI JUDITH
IPC: C12Q1/6883
Filed: 1995-10-19
Granted: 2006-06-08
Abstract: The present invention relates to the discovery of a survival motor-neuron gene or SMN gene which is a chromosome 5-SMA (Spinal Muscular Atrophy) determining gene. The present invention further relates to the nucleotide sequence encoding the SMN gene and corresponding amino acid sequence, a vector containing the gene encoding the SMN protein or a DNA sequence corresponding to the gene and transformant strains containing the SMN gene or a DNA sequence corresponding to the gene. The present invention also relates to means and methods for detecting motor neuron diseases having symptoms of muscular weakness with or without sensory changes such as amytrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), primary lateral sclerosis (PLS) and the like.
Patent DE-69606677-T2 (DE)
Inventor: KAY DAVID PAUL
IPC: A61K31/275
Filed: 1996-10-01
Granted: 2000-08-17
Abstract: Trifluoromethyl -sulphonyl or -sulphinyl phenyl 2-cyano-3-hydroxy propenamide derivs. of formula (I) and their salts are new. R1 = cyclopropyl or CH2CH=CH2; R2 = S(O)n(CF2)xCF3; n = 1 or 2; x = 0 or 1; R3 = H or 1-3C alkyl, m = 0 or 1. Also claimed are the intermediates of formula (IV).
Patent DE-69606800-T2 (DE)
Inventor: KHARE GYANESH P
IPC: C01F7/02
Filed: 1996-06-05
Granted: 2000-06-29
Abstract: A process to produce a particulate composition that comprises zinc aluminate is provided. This process comprises: (a) contacting a zinc component, an alumina component, and a dispersant component, to form a mixture; and then (b) spray drying said mixture to form said particulate composition.
Patent DE-69612486-T2 (DE)
Inventor: MUCKENFUHS RAY
IPC: A47K10/42
Filed: 1996-02-20
Granted: 2001-09-27
Abstract: A tissue package comprising a dispensing package and tissues. The dispensing package has a dispensing opening. The dispensing opening has a large aperture and an arcuately shaped smaller aperture which are spaced apart and connected by an isthmic connection. Tissues may be easily withdrawn by the user through the large aperture, and fed through the isthmic connection to small aperture. Thereafter, the tissues may be dispensed through the small aperture in a pop-up mode.
Patent DE-69617948-T2 (DE)
Inventor: GROTE MICHEL
IPC: C07C227/04
Filed: 1996-05-13
Granted: 2002-06-13
Abstract: A method of making (+/-)-3-(aminomethyl)-5-methylhexanoic acid that comprises condensing isovaleraldehyde with to form primarily reacting the with a cyanide source to form decarboxylating the to form hydrolyzing the with an alkali or alkaline earth metal hydroxide to form an alkali or alkaline earth metal carboxylate salt; and hydrogenating the alkali or alkaline earth metal carboxylate salt to form (+/-)-3-(aminomethyl)-5-methylhexanoic acid, wherein R1 and R2 are the same or different and are hydrogen, C1-C6 alkyl, aryl, benzyl, or C3-C6 cycloalkyl. The present invention also provides a method of making (+/-)-3-(aminomethyl)-5-methylhexanoic acid that comprises condensing isovaleraldehyde with to form primarily reacting the with a cyanide source to form decarboxylating the to form an alkali or alkaline earth metal carboxylate salt; and hydrogenating the alkali or alkaline earth metal carboxylate salt to form (+/-)-3-(aminomethyl)-5-methylhexanoic acid.
Patent DE-69628026-T2 (DE)
Inventor: MARKVARDSEN PETER
IPC: C12N9/00
Filed: 1996-09-04
Granted: 2004-04-08
Abstract: The invention relates to a method of identifying enzymes suitable for use in detergents, especially the selection of specific enzyme variants among a large number of such variants created through random mutagenesis. The method comprises that enzyme variants to be selected are in a mixture of enzyme variants which are each displayed on the surface of cells or phage particles, and (i) introducing the mixture into a detergent composition under conditions that will have a negative impact on the activity of or inactivate most of said enzyme variants, (ii) reacting said mixture with a catcher molecule that will bind specifically only to enzyme variants that exhibit the property sought for, (iii) separating said complex from the remaining parts of said mixture, (iv) dissociate said complex to isolate such cell(s) or phage(s) that displayed said enzyme variant without the catcher molecule, (v) introducing said phage into a host wherein it will multiply, or (va)cultivating said cell under conditions conducive to its multiplication, (vi) isolating a DNA molecule coding for said enzyme variant from the genome of said cell or phage, and (vii) determining the sequence of said DNA molecule. The invention further relates to specific materials used in said method, the enzymes selected by use of the method, and to detergent compositions comprising aid enzymes.
Patent DE-69719796-T2 (DE)
Inventor: LAW JOHN
IPC: D01F2/00
Filed: 1997-12-09
Granted: 2004-03-18
Abstract: A method of manufacture of a nonwoven cellulose fabric is disclosed. The fabric is made from fibers formed by extrusion of a solution of cellulose through a spinning jet. The extruded fiber is attenuated with a high velocity gas flow, and the attenuated fiber is collected on a surface (such as the curved surface of a rotating drum) on which the fiber web is subsequently coagulated. Apparatus for carrying out the method is also disclosed. The method and apparatus permit the manufacture of a nonwoven lyocell fabric web in which fibers are bonded together without the use of a binder.
Patent DE-69728438-T2 (DE)
Inventor: SCHUMAIER DANIEL R
IPC: H04R25/00
Filed: 1997-05-08
Granted: 2004-12-09
Abstract: A dryer appliance for demoisturizing a moisture sensitive item such as an electronic hearing aid, tooth brush, or the like, having a housing with a removable closure cap or door for providing a substantially sealed chamber and access thereto, a desiccant component mounted in the chamber, wall means substantially dividing the chamber into first and second regions, a support in the chamber for supporting at least one item within the first region, one or more passages interconnecting the first and second regions for providing a gas flow circulation path therethrough, gas moving and heater means mounted in the chamber, the circulation path of air in the chamber being such as to bring the air into recirculating contact with the gas moving and heater means and the item for a prescribed period of time to demoisturize the item.
Patent DE-69805784-T2 (DE)
Inventor: DERIFIELD M
IPC: F25D3/14
Filed: 1998-03-25
Granted: 2003-02-20
Abstract: An improved shipping container including an insulated body having a cavity for holding a product being shipped, and having one or more cavities for holding coolant in a predetermined relationship to the product. The container also includes an insulated cover adapted to sealably engage an open end of the insulated body after a product and coolant are received therein. The cover includes one or more blocks or prongs extending therefrom that are adapted to slidably engage the coolant cavities and/or the product cavity to substantially minimize air spaces in the cavities and/or seal them. The insulated body and cover preferably are formed from injection molded polyurethane, wrapped in a plastic film and inserted into a cardboard shipping carton.
Patent DE-69829107-T2 (DE)
Inventor: GARD MICHAEL
IPC: E21B47/09
Filed: 1998-12-29
Granted: 2005-12-29
Abstract: A system and method use magnetic field sensing to detect underground objects for strike avoidance. The system detects magnetic field components for both passive distortions in the magnetic field indicative of a ferromagnetic object and active magnetic fields that are impressed on an object by a signal generator. A detection module has a magnetic sensor assembly that detects the magnetic field components. The magnetic field component data is transferred through a multiplexer to an analog/digital converter to a processor. Pitch angle data from a pitch sensor and roll angle data from a roll sensor also may be transferred to the processor. The data is processed by the processor to determine the orientation of the detection module with respect to the object. The detection module may be installed in an underground boring tool or a trenching assembly. <IMAGE>
Patent DE-69832103-T2 (DE)
Inventor: ASHIDA MASANOBU
IPC: C04B41/00
Filed: 1998-11-17
Granted: 2006-05-24
Abstract: A method of electrochemical treatment of prestressed concrete which comprises supplying a direct current between a steel embedded in the prestressed concrete as a cathode and an anode on the surface or inside of the concrete at a voltage higher than the hydrogen evolution potential, wherein an effective tensile force acting on the PC steel tendon embedded in the concrete is not greater than 80% of the tensile strength of the PC steel tendon, and a method of electrochemical treatment of prestressed concrete which comprises supplying a direct current between a steel tendon embedded in the prestressed concrete as a cathode and an anode on the surface or inside of the concrete at a voltage higher than the hydrogen evolution potential, wherein the voltage is adjusted to less than the hydrogen evolution potential at least once during electrochemical treatment, and then electrochemical treatment is resumed at a voltage not lower than the hydrogen evolution potential.
Patent DE-69836341-T2 (DE)
Inventor: BRIGGS E
IPC: A23L35/00
Filed: 1998-09-25
Granted: 2007-05-31
Abstract: Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are not reverting and contain no foreign DNA and no introduced antibiotic resistance genes.
Patent DE-69837327-T2 (DE)
Inventor: HEIKENS GERARD
IPC: F04B43/02
Filed: 1998-10-14
Granted: 2007-11-22
Abstract: A safety valve (25) has a diaphragm (34) separating the larger pressure chamber (41) from the valve body liquid chamber (31). When the diaphragm pump is in an inoperative condition, the valve rod (32) is slid toward the liquid chamber (31) to close the liquid flow-in port (29a), and, when the diaphragm pump is operated to generate negative pressure in the liquid chamber (31), the valve rod (32) is slid toward the liquid balance chamber (41) to open the liquid flow-in port (29a). Accordingly, a safety valve apparatus for an air pressure operable diaphragm pump is provided in such a manner that liquid such as medical liquid is prevented from flowing toward the diaphragm pump to contaminate a surrounding environment if the diaphragm pump is damaged, and a service life of the diaphragm pump can be improved. <IMAGE>
Patent DE-69838922-T2 (DE)
Inventor: KAEWELL JOHN D JR
IPC: H04B1/707
Filed: 1998-03-04
Granted: 2008-12-18
Abstract: A communication system where the data rate of a given transmission has been encoded by a transmitter and is then used to adjust a plurality of convolutional decoders sharing common memory. The system uses common processing resources to provide up to four discrete channels having multi-rate convolutional error correction decoding resulting in a reduced silicon area and low power operation. The system is capable of supporting data communication at 8 kbps up to 64 kbps for high rate ISDN communication in receivers of both base station and consumer unit locations.
Patent DE-69900605-T2 (DE)
Inventor: MONGRENIER JEAN-CLAUDE
IPC: A61J1/10
Filed: 1999-04-13
Granted: 2002-08-14
Abstract: Assembly including a container and a device provided for computerized monitoring of a contents of the container. The device has a flexible support and one of an electronic chip and a memory card affixed to the flexible support. The flexible support comprises a printed circuit and an antenna capable of communicating with a computerized system. The antenna is one of integrated with the flexible support and attached to the flexible support. A protective compartment is provided containing a sample of the contents of the container. The flexible support is coupled to the sample. The protective compartment is removably attached to the container so as to be recouped for the purpose of one of examination or filing.
Patent DE-69902183-T2 (DE)
Inventor: BURLEY COLIN
IPC: F16L55/165
Filed: 1999-09-13
Granted: 2003-02-27
Abstract: A method of lining a pipeline (3) uses a thermoplastic liner pipe (1) which incorporates a crosslinking agent. The method comprises deforming the round liner pipe (1) into a geometrical shape having a substantially smaller overall dimension, inserting the deformed liner pipe (1) into the existing pipe (3), and reforming theliner pipe (1) to a round shape. Finally, the liner pipe (1) is expanded on to the internal surface of the existing pipe (3), and crosslinked.
Patent DE-69903645-T2 (DE)
Inventor: BORTLIK KARLHEINZ
IPC: A23L5/44
Filed: 1999-11-23
Granted: 2003-03-13
Abstract: The invention concerns a process for the extraction of lycopene from a product taken in the group consisting of tomato, tomato pomace, pink grapefruit, watermelon, guava and papaya, wherein said process comprises the following steps :   removing the impurities and water from the product by subjecting the product to at least one washing with boiling ethanol, said ethanol having a water content from 20 to 30 %, extracting the purified product by subjecting said product to at least one extraction with boiling ethanol having an alcohol content of at least 92 %, recovering the ethanol solution and cooling said solution to a temperature around the room temperature to obtain lycopene crystals and filtrating said solution to recover the lycopene crystals.ne
Patent DE-69905720-T2 (DE)
Inventor: BERGLUND ROLF
IPC: B01J39/04
Filed: 1999-06-16
Granted: 2004-01-15
Abstract: A process for separation of a compound from a solution by cation exchange. One characterizing feature is that cation exchanger used carries a number of ligands X-Y(Z)n and requires an elevated ionic strength for elution a bound compound compared to standard cation exchangers. In the ligand a) X is -O-, -S(R1)- or -N(R1)(R2)-; b) Y may be: 1) a 5 or 6 membered cyclic structure containing dou ble bonds, preferably an aromatic group, or 2) an alicyclic C5-C6 group or an aliphatic, straight or branched, C1-C3 group with the possibility that the chain joining X with Z may be interrupted by 1 or 2 ether oxygen or thioether sulphur atoms and with the proviso that X is not -O- or -S-; c) Z is cation exchanging group with a negative total charge or a protonated form thereof; and d) n is an integer > 0. The method is further characterized in that the binding is taking place at a pH at which the ligand has a net charge.