baber/WOPTO huggingface dataset:
Patent CA-2575718-A1 (CA)
Title: Salts of benzimidazole derivative with amines and process for manufacturing the same
Inventor: MIZUNO MASANORI
IPC: A61K31/4439
Filed: 2005-08-05
Abstract: The invention provides (1) a process for the production of alkali metal salts of 2-[{4-(3-methoxypropoxy)-3- methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitor, antiulcer agent, and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy) -3-methylpyridin-2-yl}methylsulfinyl]-1H- benzimidazole with amines which are intermediates for the production of the alkali metal salts and a process for the production of the same. Specifically, salts represented by the general formula (.IOTA.): wherein A+ is an isopropylammonium ion, a sec-butylammonium ion, or a cyclopentylammonium ion.
Patent CA-2577648-A1 (CA)
Title: Triazolopyridine compounds useful for the treatment of inflammation
Inventor: BALDUS JOHN EDWARD
IPC: C07D471/04
Filed: 2005-08-08
Abstract: This invention is directed generally to triazolopyridine compounds that generally inhibit p38 kinase, TNF, and/or cyclooxygenase activity. Such triazolopyridine include compounds generally corresponding in structure to the following formula (I): Wherein R1, R2, R3, R4, and R5are as defined in this specification. This invention also is directed to compositions of such triazolopyridines (particularly pharmaceutical compositions), intermediates for the syntheses of such triazolopyridines, methods for making such triazolopyridines, and methods for treating (including preventing) conditions (typically pathological conditions) associated with p38 kinase activity, TNF  activity, and/or cyclooxygenase-2 activity.
Patent CA-2578213-A1 (CA)
Inventor: CARBONARI DAVID
IPC: H01Q1/36
Filed: 2005-09-22
Abstract: An antenna apparatus includes a spiral metallic pattern formed on a portion of a circuit board on a first side thereof, the spiral pattern being formed of four arms, each arm having a contact location near the center of the spiral; a plurality of pin and ground connectors attached to a second side of said circuit board and electrically connected to the ones of the spiral arms at the contact locations thereof, said pins being connected to said arms via holes in said circuit board.
Patent CA-2579657-A1 (CA)
Title: Appareil, systeme, et procede pour la gestion de puissance de transmission dans un systeme de communication sans fil
Inventor: ODIGIE ERUMUSELE OLUMUYIWA
IPC: H04B7/005
Filed: 2005-09-08
Abstract: La présente invention a trait à un appareil, un système, et un procédé pour la gestion efficace de la puissance de transmission dans un dispositif d'équipement d'utilisateur par le maintien et l'application d'un niveau de puissance autorisée en vue de déterminer un niveau de puissance de transmission suite à une transmission de puissance limitée et avant la réception d'une nouvelle commande de contrôle de puissance. Le dispositif d'équipement d'utilisateur maintient le niveau de puissance autorisée par le contrôle et le réglage du niveau de puissance autorisée en fonction de commandes de contrôle de puissance reçues. Suite à une transmission de puissance limitée où le niveau de puissance maximale est inférieur au niveau de puissance autorisée, le dispositif d'équipement d'utilisateur détermine le niveau de puissance de transmission pour la prochaine transmission en fonction du niveau de puissance autorisée. Ainsi, après la fin de la situation de limitation de puissance, le dispositif d'équipement d'utilisateur transmet au niveau de puissance optimale éliminant les inefficacités de transmission à une puissance inférieure à la puissance autorisée avant la réception de la prochaine commande de contrôle de puissance.
Patent CA-2579900-A1 (CA)
Title: Cancerous disease modifying antibodies
Inventor: YOUNG DAVID S F
IPC: C07K16/30
Filed: 2005-03-10
Abstract: The use of a cancerous disease modifying antibody (CDMAB) 10A304.7 for treating a tumour in humans and methods of isolating and producing CDMABs. The monoclonal antibody 10A304.7 (ATTC accession number PTA-5065) is cytotoxic to cancer cells, wherein cytotoxicity is mediated via antibody dependant cell mediated cythotoxicity (ADCC) and complement-dependant cytotoxicity (CDC). The monoclonal antibody 10A304.7 is useful for delaying the dicease progression of a human tumor.
Patent CA-2585111-A1 (CA)
Inventor: BERRY STEPHEN
IPC: B60P7/06
Filed: 2005-10-14
Abstract: A load support for the attachment to the box of a pickup truck to assist in retaining loads carried by the truck employs cross members of adjustable length to accommodate pickup truck beds of varying widths. The ends of the cross member include structures for securing the ends to the top edges of the opposed side rails of the truck. The transversely extending load support includes upright members on its two ends for limiting sliding motion of loads supported on top of the cross bar. Various attachments for securing particular loads, such as bicycles or the like, to the cross bar may be fixed to the cross bar or removably attached to the cross bar through sleeves which surround the cross bar and may be fixed to it by set screws.
Patent CA-2586696-A1 (CA)
Inventor: VOON GERARD
IPC: B01J3/06
Filed: 2007-04-19
Abstract: The purpose of this invention is to artificially manufacture larger diamonds.     The device is a huge pressure and temperature press, pneumatic/hydraulic or/and a (definitely novel in decades in the field artificial manufacture of diamonds) large screw that tightens the pressure down in addition to the upper focused weight on the lower weighted platform coming together on to a central focal point. The screw is spun by a gigantic and very strong wheel, which in turn can be spun by several outer wheels.     It can also and perhaps have a combination of a very large Upper focused weight, whose supports are lifted/removed/retracted thus focusing entire weight down, giving the screw force downwards an extra boost (be cautious in design to make the screw threads very large and maybe loose - and industrial lubricant) on the diamond position, and combine it with the screw or hydraulic/pneumatic piston or press and screw down all at the same time. Or just the hydraulic/pneumatic press piston together.     Additionally we could use different shaped casings to focus onto the diamonds fillings. As well as different adding different colours, eg. translucent dyes/paints and sparkles - added to the diamond filling mix.
Patent CA-2587391-A1 (CA)
Title: Compositions useful to treat ocular neovascular diseases and macular degeneration
Inventor: LEONARD TODD
IPC: A23L33/15
Filed: 2005-11-16
Abstract: The present invention provides a composition that includes: (a) xanthophylls;  (b) vitamin C; (c) vitamin E; (d) zinc; and (e) copper. The present invention also provides a method of treating macular degeneration in a human, inhibiting angiogenesis in a human, preventing impairment of the vision or for improving impaired vision of a human whose eye has drusen, and/or treating a disease associated with ocular neovascularitis in a human. The methods include administering to a human in need of such treatment an effective amount of the composition of the present invention.
Patent CA-2587739-A1 (CA)
Title: Sphero cylindrical eye refraction system using fulid focus electrostatically variable lenses
Inventor: CAMPBELL CHARLES
IPC: A61N1/30
Filed: 2005-11-17
Abstract: Optical devices, systems, and methods can produce and/or measure cylindrical (as well as spherical) lens shapes throughout a range of both powers and cylindrical axes. Fluid focus lenses employ electrical potentials to vary the shape of a fluid/fluid interface between two immiscible fluids having differing indices of refractions by controlling localized angles between the interface and a surrounding container well. Spherical power, cylindrical power, and cylindrical access alignment may be varied with no moving parts (other than the fluids).
Patent CA-2589493-A1 (CA)
Title: Combination therapy comprising telmisartan and hydrochlorothiazide
Inventor: SCHUMACHER HELMUT E
IPC: A61P9/12
Filed: 2005-12-09
Abstract: A pharmaceutical composition comprising about 80 mg telmisartan and about 25 mg hydrochiorothiazide or about 160 mg telmisartan and about 50 mg hydrochlorothiazide for the treatment of hypertension in patients with an insufficient blood pressure reduction upon treatment either with an angiotensin II receptor antagonist, or a pharmaceutical composition of an angiotensin II receptor antagonist and a low dose of hydrochiorothiazide.
Patent CA-2589780-A1 (CA)
Title: Height- and angle-adjustable motion disc implant
Inventor: DINELLO ALEXANDRE
IPC: A61F2/30
Filed: 2005-11-16
Abstract: An endplate for a prosthetic intervertebral disc is disclosed wherein the height or angle of the disc can be adjusted. In one embodiment, the endplate comprises an outer plate (51) having a threaded recess (56) and a threaded inner plate (61) having an articulating surface (65). Further disclosed is an intervertebral disc comprising a first endplate with a movable wedge therein.  The wedge acts either on a second flexible endplate or to an inner plate received in a recess of the first endplate in order to adjust the height of the intervertebral disc.
Patent CA-2595298-A1 (CA)
Title: Ionic liquids derived from peracid anions
Inventor: SHOWELL MICHAEL STANFORD
IPC: C07C409/24
Filed: 2006-02-16
Abstract: A novel class of ionic liquids and methods for their preparation are disclosed. Specifically, these novel ionic liquids can be derived from peracid anions. The present invention also relates to compositions containing these novel ionic liquids and method of using the same.
Patent CA-2596299-A1 (CA)
Inventor: PRPICH ROBERT M
IPC: B42C3/00
Filed: 2007-08-03
Abstract: A method of constructing an origami-style booklet from a unitary blank of sheet material. The blank of sheet material is divided into eight equal rectangles.  The blank of sheet material is then cut widthwise along one of three notional boundary lines separating two of the rectangles, from one of opposed side edges to a notional centerline.  The blank of sheet material is then lengthwise along the notional centerline starting one rectangle in from a top edge to one rectangle in from a bottom edge. The blank of sheet material is then folded lengthwise in accordian fashion about the three boundary lines and widthwise along the notional centerline until the rectangles are in face to face relation forming a booklet consisting of a front cover, a back cover and eight interior writing surfaces.
Patent CA-2598143-A1 (CA)
Title: Diamond bit steel body cutter pocket protection
Inventor: LOCKSTEDT ALAN W
IPC: B23P15/32
Filed: 2007-08-20
Abstract: A drill bit that includes a steel bit body having at least one blade thereon, at least one cutter pocket disposed on the at least one blade; at least one cutter disposed in the at least one cutter pocket; at least one recess formed in at least a portion of the surface of the at least one cutter pocket, wherein the recess is adjacent a leading face of the at least one blade; and an erosion resistant material in the at least one recess is disclosed.
Patent CA-2599033-A1 (CA)
Title: Method for determining chemical pulp kappa number with visible-near infrared spectrometry
Inventor: BETTS STEPHEN P A
IPC: D21C9/02
Filed: 2006-02-28
Abstract: A method for the determination of cellulosic-fibre properties, such as, residual lignin content of chemical pulp, with the aid of a spectroscopic technique obtained over a range covering the visible and the near-infrared regions of the electromagnetic spectrum, comprising the steps of obtaining a sample from the process line, minimally removing some excess water, exposing the fibres in the sample to a large beam light source, optionally moving the sample at a constant speed, and acquiring the spectral data over a pre-determined length of time, and correlating the spectrum to a previously determined calibration so as to determine the Kappa number. Alternatively, as an arrangement for process control, the instant invention includes the mounting of the excitation light source and fibre-optic probe along the various locations of the kraft cooking and bleaching process, such as 1) at the drum brownstock washers and 2) throughout the bleach plant deckers, located just before the doctored blade, the probe being connected to a fast scanning spectrometer, via fibre optic cables, with a computer sequencing spectral acquisition and correlating the spectrum against a predetermined calibration, and logging the results.
Patent CA-2599182-A1 (CA)
Title: Regulators of protein misfolding and aggregation and methods of using the same
Inventor: CALDWELL GUY A
IPC: A61K31/00
Filed: 2006-02-27
Abstract: Polynucleotide molecules and the proteins encoded by the molecules, diagnostic and treatment methods for neurological disorders characterized by protein aggregation are provided. Genes are described herein that affect the misfolding of, and subsequent aggregation of, aggregation-prone proteins such as alpha-synuclein and have implications for the diagnosis and treatment of neurological diseases related to protein aggregation such as Parkinson's disease. Knockdown of expression of the genes described herein using RNAi results in alpha-synuclein protein aggregation in a C. elegans model of protein aggregation. Dopaminergic neuroprotection after exposure to the neurotoxin 6-OHDA or overexpression of alpha-synuclein may also be provided by overexpression of proteins. Knowledge of genes relating to protein misfolding and aggregation provides powerful means to develop diagnostic screening methods, mutation analysis and drug design information for the development of novel therapeutic and neuroprotective compounds to treat neurodegenerative diseases such as Parkinson's disease.
Patent CA-2599974-A1 (CA)
Title: Pyridine-2-carboxamide derivatives as mglur5 antagonists
Inventor: KOLCZEWSKI SABINE
IPC: C07D417/14
Filed: 2006-02-23
Abstract: The invention relates to compounds of formula (I) wherein R1 to R3 are as defined in the description and claims, to processes for their preparation, pharmaceutical compositions containing them, and uses thereof for the preparation of medicaments useful for treating CNS disorders.
Patent CA-2600821-A1 (CA)
Inventor: KRITZIK MARCIE R
IPC: G01N33/53
Filed: 1999-12-13
Abstract: The invention provides animal models, where the ectopic expression of KGF, EGF, or both is under the control of a pancreas-specific promoter, e.g., the insulin promoter. The expression of KGF in the ins-KGF pancreatic inslets of Langerhans results in enlarged islets, with substantial proliferation of duct cells within the islet mass, and the presence of albumin and alpha-fetoprotein-producing hepatocytes in the islets of the ins-KGF  pancreata. The compositions and methods disclosed are useful for identifying and isolating pancreatic stem/progenitor cells, including a common stem/progenitor to liver cells and pancreatic cells.
Patent CA-2600822-A1 (CA)
Title: Method for preventing cardiovascular diseases
Inventor: KLEIN THOMAS
IPC: A61K31/415
Filed: 2006-03-14
Abstract: The invention relates to a method for selecting COX-2 selectice NSAIDs which have a salutary thera- peutic profile. The invention further relates to the use of these selected COX-2 selectice NSAIDs in the treatment of certain diseases. The invention yet further relates to combinations comprising COX-2 selective NSAIDs and the use of these combinations.
Patent CA-2601194-A1 (CA)
Inventor: OH SEUNGMIN
IPC: G06F1/20
Filed: 2007-09-07
Abstract: This invention provides a computer case that can be filled with non-conductive oil with high heat capacity for the purpose of cooling computer parts without cooling fans. All computer parts excepting hard drive and optical drive with moving parts are submerged in oil in a completely sealed case provided in this invention. Hard drive and optical drive are installed on the exterior of main unit, one of three major component parts of the case. Advantageously, hard drive is installed on specially designed hard drive holder in the form of a heat sink, one side of which is in direct contact with the oil in the sealed case, which cools the heat produced by the hard drive. The opposite side of a heat sink installed on the bottom of the case, which protrudes into the case and comes in direct contact with the oil, cools the temperature of the oil naturally by absorbing and dissipating heat. The addition of low-noise cooling fan installed in the centre of the heat sink speeds up the cooling process.
Patent CA-2602825-A1 (CA)
Title: Handheld device for retrieving and analyzing data from an electronic monitoring device
Inventor: ROBERTS WILLIAM PEYTON
IPC: G01D9/00
Filed: 2006-03-28
Abstract: The invention is a handheld device that is adapted for wireless communication with an electronic monitoring device, and includes a control unit and dedicated operating system configured to analyze data retrieved from a data logger and determine if the electronic monitoring device has been exposed to an environmental condition exceeding a predetermined threshold. In some embodiments, the handheld device may be configured to generate a sensory output if the data indicates that the predetermined threshold may have been exceeded. The handheld device may also have an associated memory component configured to store the retrieved data. In some embodiments, the reader may also be configured to calculate the remaining shelf-life of an item that is in a monitoring relationship with the electronic monitoring device.
Patent CA-2604853-A1 (CA)
Inventor: NELSON BABACK
IPC: G09F23/00
Filed: 2007-09-28
Abstract: Presented is a package of tissue rolls, the package including two package sides, a package bottom, a package back, and a package top; a package front in a generally vertical orientation, the package front spaced apart from and generally parallel to the package back, wherein the package front and the package back are coupled to and generally orthogonal to the package bottom, the package front including a primary package logo having a logo axis; and a plurality of tissue rolls, each tissue roll having a roll height, a roll diameter, and a longitudinal axis, wherein each of the longitudinal axes are generally horizontal when the logo axis is generally vertical.
Patent CA-2606023-A1 (CA)
Title: Method to transform bulk material
Inventor: REEVES ROBERT A
IPC: B02C19/00
Filed: 2006-04-28
Abstract: The invention provides low-cost, non-thermal methods to transform and beneficiate bulk materials, including low rank coals such as peat, lignite, brown coal, subbituminous coal, other carbonaceous solids or derived feedstock. High pressure compaction and comminution processes are linked to transform the solid materials by eliminating interstitial, capillary, pores, or other voids that are present in the materials and that may contain liquid, air or gases that are detrimental to the quality and performance of the bulk materials, thereby benefÊciating the bulk products to provide premium feedstock for industrial or commercial uses, such as electric power generation, gasification, liquefaction, and carbon activation. The handling characteristics, dust mitigation aspects and combustion emissions of the products may also be improved.
Patent CA-2606284-A1 (CA)
Title: Biocompatible polymers and co-polymers, and uses thereof
Inventor: HITZ HANS
IPC: A23L29/00
Filed: 2006-05-22
Abstract: The invention relates to highly biocompatible or biophilic un-cross-linked or cross-linked polymers comprising one or more side-chain active acrylic amino acids of formula (I). The invention further concerns various highly biocompatible, cross-linked co-polymers comprising one or more monomers of formula (I), and one or more other polymerizable monomers. Uses of such polymers and co-polymers for the production of contact lenses, intraocular lenses, implants, wound healing slabs, additives for food and cosmetics, conductive plastics, spinnable fibers, and the like are disclosed.
Patent CA-2606471-A1 (CA)
Title: Benzisoxazole piperidine compounds and methods of use thereof
Inventor: EDGAR DALE M
IPC: C07D413/04
Filed: 2006-04-26
Abstract: The invention includes benzisoxazole piperidine compositions and methods of using them for modulating sleep.
Patent CA-2606969-A1 (CA)
Inventor: LAURYSSEN GARY PIERRE
IPC: A61F2/12
Filed: 2006-04-28
Abstract: The invention comprises a soft tissue support (1) in the form of a biocompatible resilient layer with a predetermined shape and means to secure the support subcutaneously. The support may be a generally L-shaped or U-shaped and be manufactured from a biocompatible resilient mesh.
Patent CA-2610378-A1 (CA)
Title: Method for producing a metallic component comprising adjoining portions having differing material properties
Inventor: BEENKEN HEIKO
IPC: C21D9/46
Filed: 2006-05-24
Abstract: The invention relates to a method for producing a metallic component (B), whereby adjacent regions (Z1, Z2, Z3) having different material properties can be produced on the metallic component (B) in a simple manner. According to said method, a sheet metal element (E) heated to a forming temperature is shaped in a form tool (1) into an end component (B). The form tool (1) comprises a tempering device for regulating the temperature of at least one of the sections (5,7,16) thereof that comes into contact with the sheet metal element (E) during the forming process. The forming speed is controlled in such a way that the component regions with the desired increased hardness come into contact with the cooled form tool faster than adjacent regions with the desired reduced hardness. The invention is especially suitable for shaping sheet metal elements of different thicknesses that are interconnected with a material fit (tailored blanks).
Patent CA-2611680-A1 (CA)
Inventor: BAUMANN CHRISTIAN ANDREW
IPC: A61K31/506
Filed: 2006-06-07
Abstract: The invention is directed to a method of inhibiting FLT3 tyrosine kinase activity or expression or reducing FLT3 kinase activity or expression in a cell or a subject comprising the administration of a farnesyl transferase inhibitor and a FLT3 kinase inhibitor selected from thienopyrimidine and thienopyridine compounds Formula I' and Formula II': where R1, R3, B, Z, Q, p, q and X are as defined herein. Included within the present invention is both prophylactic and therapeutic methods for treating a subject at risk of (or susceptible to) developing a cell proliferative disorder or a disorder related to FLT3.
Patent CA-2612910-A1 (CA)
Title: Procede de fabrication de plis courriers et machine mettant en oeuvre ledit procede
Inventor: FREYBURGER HUBERT
IPC: B43M3/04
Filed: 2006-07-24
Abstract: La présente invention concerne un procédé de fabrication de plis courriers personnalises et uniques, offrant une solution complète, intégrant la fabrication des enveloppes à celle des documents à mettre sous pli, permettant de travailler à des vitesses élevées, de garantir l'intégrité et la confidentialité des plis et de réduire leur coût global unitaire. La machine de fabrication (1) de plis courriers (100) comporte notamment un dispositif d'impression (2) agencé pour imprimer sur une même laize de papier (10) les documents (13) à mettre sous pli et les enveloppes (14) destinées à contenir les documents (13), l'un à la suite de l'autre dans l'ordre de la mise sous pli, chaque enveloppe étant précédée ou suivie du ou des documents qu'elle doit contenir, un dispositif de coupe longitudinale (3) agencé pour mettre lesdits documents (13) à la bonne largeur et pour former les rabats (16) des enveloppes (14), un dispositif de coupe transversale (4) agencé pour séparer les documents (13) et les enveloppes (14) en les mettant à la bonne longueur, un dispositif d'assemblage (7, 8) des documents (13) avec l'enveloppe (14) qui leur correspond, un dispositif de collage et de pliage (9) pour fermer le pli courrier (100) obtenu et une unité centrale de commande qui pilote au moins les dispositifs de coupe en fonction du nombre et du format des documents et de l'enveloppe des plis courriers à fabriquer. Application : Courriers en nombre tels que routage, transactionnel, hybride, etc.