baber/WOPTO huggingface dataset:
Patent RU-2758950-C1 (RU)
Title: Method for diagnosing hepatic pathologies in dogs using cfa-mirnas
Inventor: Khassan Akhmed Mokhammed El Sebaej Ali
IPC: C12N15/00
Filed: 2020-09-21
Granted: 2021-11-03
Abstract: FIELD: biotechnology. 
     SUBSTANCE: invention relates to the field of veterinary science and biotechnology. Proposed is a method for using circulating caninefamiliaris (cfa) microRNAs (miRNAs) produced from hepatocytes as new non-invasive diagnostic biomarkers for accurately reflecting the type of ongoing hepatic pathologies in dogs with different morphologies of extrahepatic and intrahepatic congenital portosystemic shunts (ICPS). The method is implemented by extracting the total RNA from serum samples of dogs with the confirmed presence of ICPS and various hepatic pathologies, followed by reverse transcription with subsequent amplification in RT-PCR in real time using canine-specific primers for cfa-miR-122-5p, cfa-miR-34a-5p, cfa-miR-21-5p and cfa-miR-126-5p. All analyses were applied in three repeats for each sample, and the resulting average cycle threshold (Ct) for each tested microRNA was normalised relative to the average Ct of cfa-miRNA-16 (stably expressed endogenous control) and cel-miRNA-39 (exogenous spike in the control). The relative multiple change in each tested cfa-miRNA in the groups of ICPS compared to the corresponding healthy controls was then determined using the 2 -Δ Δ Ct  method. Tests have proved that cfa-miR-122 at a threshold value of ≥1.32 to 1.45 constitutes a diagnostic tool for microvesicular steatosis. Cfa-miR-34a at a threshold value of ≥ 1.15 to 1.23 constitutes a diagnostic tool for vacuolated hepatocytes with macrovesicular steatosis, as well as lipid or pigmented granuloma. Cfa-miR-21 at a threshold value of ≥ 1.07 to 1.23 constitutes a diagnostic tool for portal and parenchymal fibrosis. Cfa-miR-126 at a threshold value of ≥ 1.14 to 1.16 constitues a diagnostic tool for changing the hepatic blood supply in the form of arteriole proliferation and duct proliferation associated therewith in dogs with ICPS.  
     EFFECT: invention provides a possibility of using the selected serum cfa-miRNAs as new non-invasive biomarkers for reflecting the histopathological and molecular events occurring in the liver in each type of shunt with high degree of sensitivity and specificity. 
     1 cl, 1 tbl
Patent RU-2748120-C1 (RU)
Title: Posture correction method
Inventor: Sokolova Natalya Nikolaevna
IPC: A61H1/00
Filed: 2020-10-09
Granted: 2021-05-19
Abstract: FIELD: orthopedics.SUBSTANCE: invention relates to orthopedics, namely to methods of posture reconstruction, and can be used to correct posture in health institutions. A preliminary photograph of the client is carried out in profile and the impact on his muscles in four stages. In the first stage, the specialist places one hand under the knee, and the other hand on the surface of the thigh, and smooths the muscles towards each other. The second stage is carried out by influencing the muscles of the back in four stages, when the specialist smooths the muscles of the client's back with repeated movements of the hand. The specialist performs the third stage of influence on the muscles of the shoulder girdle in two stages, at the first stage it smoothes the muscles in the direction of the shoulder joint, and at the second stage it smoothes the trapezius muscle. At the fourth stage of impact on the muscles of the cervical spine, the specialist places one hand under the occipital bone and raises the client's head, and with two fingers of the second hand passes along the vertebrae to the seventh vertebra, and gradually returns to the occipital bone. The specialist performs each stage of the procedure up to five times, and after the end of each session takes a photograph of the client and conducts the sessions until the posture correction process is visible, according to the photographs taken.EFFECT: provides stable posture correction due to muscle memory in a procedure limited to 3-5 sessions.1 cl, 9 dwg
Patent RU-2749343-C1 (RU)
Title: Method for removing indicator penetrating liquid from surface of glass-ceramic products using ultrasonic waves
Inventor: Minin Sergei Ivanovich
IPC: B08B3/12
Filed: 2020-10-22
Granted: 2021-06-08
Abstract: FIELD: dye capillary flaw detection.  
     SUBSTANCE: invention relates to the field of non-destructive testing of products made of non-porous (P <2%) glass-ceramic materials, namely, dye capillary flaw detection for surface discontinuities and serves to exclude excessive thermal loads on fragile products, reduce labor and energy costs during testing. A method is proposed for removing an indicator penetrating liquid from the surface of glass-ceramic products using ultrasonic waves in order to increase the efficiency of removing penetrant into washing solutions heated to + 40-60°C, initially acidic and then alkaline, an ultrasonic wave is introduced from scattering ultrasonic transducers with a frequency of 38-42 kHz and a power of 6 kW, while the total time of ultrasonic cleaning is from 1 to 3 hours, in the process of ultrasonic cleaning, glass-ceramic products rotate. 
     EFFECT: invention improves efficiency of removing the penetrant from the surface of glass-ceramic products after color capillary flaw detection without heat treatment (burning out). 
     1 cl, 2 dwg
Patent RU-2768834-C1 (RU)
Title: Coatings for textured 3d printed substrates
Inventor: KRAUT NADINE D
IPC: C08J7/046
Filed: 2019-04-09
Granted: 2022-03-24
Abstract: FIELD: 3D printing.SUBSTANCE: invention relates to a coated product. The coated product includes a product with a surface containing a set of low-profile elements. At the same time, the set of low-profile elements has surface roughness from 10 mcm to 200 mcm. In this case, the surface also contains a set of topographic elements with an average height that is more than 4 times greater than the average height of low-profile elements, and a coating system covering the surface. At the same time, the coating system contains one or more coating layers. In this case, the coated surface has surface roughness of less than 10 mcm, and the coating system has an average thickness between low-profile elements of ±50% of the surface roughness of the set of low-profile elements.EFFECT: visual hiding of low-profile surface elements and giving optical properties to high-profile surface elements.40 cl, 28 dwg, 3 tbl, 6 ex
Patent RU-2753533-C1 (RU)
Title: Method for modifying sulfate lignin
Inventor: Garkotin Anton Iurevich
IPC: C07G1/00
Filed: 2020-12-02
Granted: 2021-08-17
Abstract: FIELD: sulfate lignin modifying. 
     SUBSTANCE: invention relates to methods for modifying sulfate lignin. A method is proposed for modifying sulfate lignin by preliminary synthesis of acetyl nitrate from concentrated nitric acid and acetic anhydride to obtain a solution of acetyl nitrate in acetic acid, preparing a dioxane solution of sulfate lignin, mixing the resulting solutions and holding the reaction mixture with stirring, followed by isolation of modified sulfate lignin. 
     EFFECT: invention improves efficiency of obtaining nitro derivatives of acetylated sulfate lignin. 
     3 cl, 1 tbl, 10 ex
Patent RU-2760568-C1 (RU)
Title: Starter-generator with stator winding with different conductor cross-sections
Inventor: Ismagilov Fliur Rashitovich
IPC: H02P6/20
Filed: 2021-03-25
Granted: 2021-11-29
Abstract: FIELD: electrical engineering.SUBSTANCE: invention relates to electrical engineering and can be used in starter-generator systems for electric vehicles. The starter generator contains a stator winding of several parts, at least one part of the stator winding has a conductor cross-section that is different from the cross-section of another part of the stator winding. Parts of the stator winding with different conductor cross-sections are separated by taps, open when operating in the starter mode with the possibility of current flowing through the entire stator winding and closed when operating in generator mode with the formation of a neutral, with the possibility of current flowing along a part of the stator winding with conductors of a larger cross-section.EFFECT: reduction of heating of the stator winding due to the implementation of a part of the winding from a wire of a larger cross-section.1 cl, 1 dwg
Patent RU-2764439-C1 (RU)
Title: Method for obtaining an extract from quinoa grains enriched with phytoecdysteroids
Inventor: ZORIN SERGEJ NIKOLAEVICH
IPC: A61K131/00
Filed: 2021-04-09
Granted: 2022-01-17
Abstract: FIELD: biotechnology.  
     SUBSTANCE: invention relates to biotechnology, namely to a method for obtaining an extract from quinoa grains. The method for obtaining an extract from quinoa grains includes grinding and sieving the grains through a sieve with a pore size of 0.35 mm, then 2-stage extraction: at the first stage, the crushed grains are extracted with 500 ml of 20-60% ethyl alcohol solution and at a ratio of 1:20 g/ml, respectively, at room temperature for 1 hour, clarified by centrifugation for 30 minutes on a BEKMAN J-6B centrifuge at 4000 rpm and the supernatant is selected, at the second stage the resulting precipitate is extracted with 250 ml of 20-60% solution of ethyl alcohol under similar conditions, at a ratio of 1:10 g/ml, respectively, at room temperature for 45-60 minutes, followed by centrifugation, the supernatant is selected and combined with the one obtained at the first stage, ultrafiltration is carried out through a membrane with a pore size of 10 kD, with the collection of a low-molecular fraction, which is then subjected to reverse osmotic concentration, followed by removal of ethanol under vacuum on a rotary evaporator, passing this concentrate through a column with a hydrophobic sorbent, washing the sorbent with water and subsequent desorption of phytoecdysteroids, flavonoids and polyphenols with 70-75% ethyl alcohol, removal of ethanol from the alcohol flush under vacuum on a rotary evaporator and lyophilic drying.  
     EFFECT: method makes it possible to obtain an extract (concentrate) from quinoa grains enriched with phytoecdysteroids (mostly 20-hydroxyecdysone) and flavonoids.  
     1 cl, 3 ex
Patent RU-2763761-C1 (RU)
Title: Hepatoprotective humic agent
Inventor: MILOV NIKOLAJ IVANOVICH
IPC: A61K35/10
Filed: 2021-04-13
Granted: 2022-01-10
Abstract: FIELD: pharmaceutical industry.  
     SUBSTANCE: invention relates to the pharmaceutical industry, namely to a drug with hepatoprotective activity. The agent with hepatoprotective activity is a colloidal solution containing water, humic substances representing humic and fulvic acids and their salts, hydroquinone and chrysin, and the size of colloidal particles is in the range from 30 nm to 10 microns, the mass of humic substances is from 1 to 20 wt. % hydroquinone is contained in an amount not exceeding 3 wt. % of the mass of humic substances, and chrysin in an amount not exceeding 2 wt. % of the mass of humic substances.  
     EFFECT: humic agent described above contains a wide range of humic substances and has no chemical impurities, it is effective as a hepatoprotective agent.  
     1 cl, 2 tbl, 3 ex
Patent RU-2758009-C1 (RU)
Title: Film fastening machine
Inventor: ZHALYBIN OLEG NIKOLAEVICH
IPC: A01G9/14
Filed: 2021-04-15
Granted: 2021-10-25
Abstract: FIELD: agriculture. 
     SUBSTANCE: invention relates to agriculture, in particular greenhouses. The machine contains a frame with a rotating axis for a roll of film, as well as rollers for laying a film and a jamming element. An annular groove is made on the outer surface of the rollers. Each roller for placing the jamming element has a coil of the jamming element. The machine is equipped with pressure wheels located under the surface of the roller support. These wheels can move in and out of the roller bearing surface. 
     EFFECT: use of the invention will improve the reliability of fixing the film. 
     5 cl, 13 dwg
Patent RU-2761969-C1 (RU)
Title: Multi-phase rectifier
Inventor: SHUVAEV YURIJ NIKOLAEVICH
IPC: H02M7/08
Filed: 2021-04-19
Granted: 2021-12-14
Abstract: FIELD: electrical engineering. 
     SUBSTANCE: invention relates to the field of electrical engineering, in particular, converter technology, and can be used in the design of secondary power supplies for electrical and electronic equipment for various purposes. A polyphase rectifier with several independent filter chokes contains n simple rectifiers and n filter chokes, the number of which is either a multiple of two or three, connected to the parallel-connected output capacitor and the total load through the main and compensating windings of its own choke. The number of turns of the windings are equal to each other. The end of the main winding of each choke is connected to the end of the compensating winding of the choke connected to the output of another simple rectifier, i.e. the main and compensating windings are turned on in the opposite direction, and the beginning of the compensating windings of all chokes are connected to the load. 
     EFFECT: reducing the volume and weight of various multiphase rectifiers with several independent filter chokes by reducing the volume and weight of a set of chokes by eliminating a non-magnetic gap in their magnetic circuit and introducing a compensating winding. 
     3 cl, 6 dwg
Patent RU-2766292-C1 (RU)
Inventor: Belozerova Natalya Sergeevna
IPC: A61P31/14
Filed: 2021-08-05
Granted: 2022-03-14
Abstract: Изобретение относится к биотехнологии. Описана фармацевтическая композиция, предназначенная для индукции специфического иммунного ответа против вируса острого респираторного синдрома SARS-CoV-2, содержащая нуклеокапсидный белок SARS-CoV-2. Вакцина имеет следующий состав на 1 мл: нуклеокапсидный белок NSARS-CoV-2, имеющий аминокислотную последовательность SEQIDNO: 1 20-100 мкг; сквалан  15-40 мг; α-токоферол 5-15 мг; полисорбат 80  1-10 мг; натрий фосфорно-кислый двузамещенный  0,1-2,0 мг; калий фосфорнокислый однозамещенный  0,01-0,25 мг; калия хлорид  0,01-0,2 мг; натрия хлорид  0,1-8,5 мг; вода для инъекций  до 1 мл. Также представлен способ получения указанной композиции, который включает: обеспечение нуклеокапсидного белка NSARS-CoV-2, имеющего аминокислотную последовательность SEQ ID NO: 1, в количестве от 20 до 100 мкг/мл; растворение белка в водном растворителе и доведение содержания белка N в растворе до требуемой концентрации; приготовление водного раствора адъюванта; смешение водного раствора, содержащего белок N, и водного раствора адъюванта; гомогенизация полученной смеси до получения однородного по цвету раствора; регулирование полученной композиции рН до 7,2-7,6. Изобретение позволяет получить стабильную композицию, способную при ее введении в организм вызвать иммунный ответ и индуцировать специфический иммунный ответ против SARS-CoV-2. 3 н. и 7 з.п. ф-лы, 3 ил., 8 табл., 7 пр.
Patent RU-2770961-C1 (RU)
Inventor: Shcherbak Yurij Ivanovich
IPC: G01N3/18
Filed: 2021-09-14
Granted: 2022-04-25
Abstract: FIELD: objects testing.SUBSTANCE: invention relates to the field of testing objects for the combined effects of external factors. The test method consists in the simultaneous impact on the test object (TO), placed in a climatic chamber, mechanical and thermal loads. Prior to installation in the climatic chamber, the TO is installed through heat-insulating plates between the base and the adapter plate of the technological device, containing the base connected by guides to the adapter and top plates, packs of sequentially assembled Belleville springs placed between the plates on the guides, clamping nuts mounted on the guides above the top plate. The TO in the technological fixture is loaded on a press machine along the TO axis to a predetermined compressive force, the stress-strain state of the TO is fixed by screwing nuts on the guides of the TO, then the TO in the production jigs is placed in a climatic chamber and the temperature is applied to the TO.EFFECT: approximation of test modes to real operating conditions with the provision of temperature effects on the TO at a temperature difference and a given compressive force.1 cl, 3 dwg
Patent DE-2114696-C2 (DE)
Title: Thrust bearing assembly with two bearings - has distance rings and races of identical height, with race bearing surfaces extending over partial height sections
IPC: F16C19/30
Filed: 1971-03-26
Granted: 1982-08-19
Abstract: The axial bearing assembly comprises several ball or roller bearings, one behind the other. Each has an inner and an outer race of triangular cross-section. The outer and inner races are spaced from each other in the axial direction by intermediate rings. All distance rings (4,5) and all races (1,2) have the same height in the axial direction, where the rings bear against the races. The cylindrical seat faces (6,7) of the latter in the housing and on the shaft extend for only part of their axial height. All races and rings are highly prestressed in the axial direction.PS.
Patent DE-3041340-C2 (DE)
IPC: B22D17/14
Filed: 1980-11-03
Granted: 1987-06-25
Abstract: A diecasting process for producing cast pieces for metals or their alloys by means of a horizontal cold chamber diecasting machine. The diecasting machine includes a diecasting mold held under a vacuum, a fill chamber coupled to the diecasting mold, a holding furnace containing metal melt, a suction pipe partially immersed in the holding furnace and coupled to the fill chamber, means for transporting metal melt from the holding furnace through the suction pipe into the fill chamber under a vacuum, and means for moving the metal melt from the fill chamber into the diecasting mold. During the dosaging phase when the fill chamber is filled with metal melt, gases and lubricant vapors are developed upon entry of the melt into the fill chamber. The process includes the steps of maintaining the vacuum in the fill chamber during the dosaging phase until the gases and lubricant vapors so developed have been substantially extracted and maintaining the vacuum in the fill chamber to its maximum extent until the diecasting mold is completely filled with the metal melt.
Patent DE-3106945-C2 (DE)
Title: Verfahren zur Herstellung von Estern der Acrylsäure oder Methacrylsäure
IPC: C07C67/39
Filed: 1981-02-25
Granted: 1983-07-07
Abstract: Gegenstand der Erfindung ist die Herstellung von Acrylsäure- oder Methacrylsäureestern durch Oxidation von Propylen bzw. Isobutylen in der Flüssigphase in Gegenwart eines geradkettigen niederen Alkohols und von molekularem Sauerstoff nach einem Verfahren, das dadurch gekennzeichnet ist, daß man die Reaktion in Gegenwart von  1) einem Katalysator, der aus Palladium und wenigstens einem Metall aus der aus Blei, Wismut, Thallium, Tellur und Quecksilber bestehenden Gruppe, vorzugsweise einer intermetallischen Verbindung von Palladium und dem genannten Metall besteht,  2) wenigstens einer Verbindung aus der aus Mineralsäuren, Heteropolysäuren, Salzen von Heteropolysäuren, Molybdänsäuren und organischen Sulfonsäuren bestehenden Gruppe, vorzugsweise von Heteropolysäuren oder ihren Salzen, und  3) gegebenenfalls wenigstens einer Verbindung aus der aus Alkalimetallverbindungen und Erdalkalimetallverbindungen bestehenden Gruppe durchführt. Bei diesem Verfahren ist die Aktivität hoch, auch wenn die Reaktion bei niedrigen Temperaturen durchgeführt wird; die Nebenproduktmenge ist gering, und der gewünschte Ester kann mit hoher Selektivität gebildet werden.
Patent DE-3112894-C2 (DE)
Title: Sende- und Empfangseinheit für in Fernsprechvermittlungsanlagen, insbesondere in kleinen Nebenstellenanlagen zu übertragende binäre Steuerdatensignale
IPC: H04Q1/39
Filed: 1981-03-31
Granted: 1985-06-27
Abstract: In sogenannten kleinen Fernsprechnebenstellenanlagen werden zwischen einer zentralen Einrichtung (ZE) und den mit ihr verbundenen Endeinrichtungen (Fernsprechapparate (T1-Tn) wechselseitig binäre Datensignale übertragen. Zur Übertragung von Einstellinformationen für an den Endeinrichtungen vorhandenen optischen und/oder akustischen An zei ge elemente (A) werden als Binärwerte unipolare Impulse ausgesendet, die sich sowohl in ihrer Impulsamplitude als auch in ihrer Zeitdauer unterscheiden. Für die in der Gegenrichtung zu übertragenden Informationen (Tastenbetätigung) dienen als Binärwerte ein bipolarer Impuls und ein dem Ruhepotential der Leitung entsprechender impulsloser Zu stand. Die Übertragungsleitung ist beidseitig mit einem Sende-Empfangsübertragen (Uz, Ut) abgeschlossen, der zu sätzlich zur leitungsseitigen Wicklung (Wz3, Wt3) eine Sende- (Wz2, Wt2) und eine Empfangswicklung (Wz1, Wt1) aufweist. Zur Erzeugung der als Binärzeichen in der einen Übertragungsrichtung verwendeten unipolaren Impulse ist durch eine entsprechende Steuereinheit (STz) jeweils ein elektronischer Schalter (T1 bzw. T2), von denen der eine (T1) unmittelbar und der andere (T2) über einen Vorwiderstand (R8) mit der ihrerseits an die Versorgungsspannung angeschalteten Sendewicklung (Wz2) in Reihe liegt, wirksam schließbar. Zur Erzeugung eines bipolaren Impulses sind zwei elektronische Schalter (T3, T4) mit der Sendewicklung in der Weise ge koppelt, daß durch das nacheinander vorgenommene kurzzeitige ..
Patent DE-3116830-C2 (DE)
Title: Abdeckvorrichtung für offene Behälter beliebiger Füllungen
IPC: E04H4/10
Filed: 1981-04-28
Granted: 1984-10-31
Abstract: Abdeckvorrichtung für offene Behälter beliebiger Füllung, welche im Behälterbau, der Galvanik oder auf dem Gebiet des Umweltschutzes sowie im Schwimmbadbau und Vorratsbehälterbau eingesetzt wird, um mittels Mehrschichtfolien und anderem Material Ausdünstung, Verdampfung, Auskühlung bzw. Erwärmung und Verschmutzung des Behälterinhaltes zu vermeiden. Damit keine unpraktischen Erhöhungen um den abzudeckenden Behälter entstehen, wird die Abdeckvorrichtung an oder hinter einer Behälterseite versenkt stationiert. Diese Abdeckvorrichtung besteht aus einem bodengleichen Deckel, an dessen Unterseite mittels zwei seitlichen Lagerschildern eine freitragende Wickelwelle montiert ist. Der Deckel wird hydraulisch, pneumatisch oder mittels Zahnstange und ähnlichem einseitig zum Behälter geöffnet, damit das auf der Wickelwelle aufgerollte flexible Abdeckmaterial, ausgehend über dem Höhenniveau des Behälterinhaltes und des Behälterrandes, auf den Behälter bzw. von ihm gezogen werden kann. Wesentlich ist dabei, daß der Deckel und die Wickelwelle eine Einheit bilden und mit dem Öffnen des Deckels die Welle mit dem aufgerollten Abdeckmaterial das entsprechende Höhenniveau erreicht. Bisher wurden solche Abdeckvorrichtungen so angeordnet, daß im Umfeld des Behälters Stufen und je nach Größe des Behälters eine Beeinträchtigung der Sicht auf den Behälterinhalt bestand. So wurde die freie Einsicht in ein Schwimmbecken, im öffentlichen Bereich von den Unfallverhütern vorgeschrieben, nicht mehr .......
Patent DE-3118263-C2 (DE)
Title: Türbetätigungseinrichtung
IPC: E05F15/50
Filed: 1981-05-08
Granted: 1986-04-30
Abstract: Es wird eine Türbetätigungseinrichtung vorgeschlagen, die mit einem Türventil (9) zum druckluftbetätigten Hin- und Herbewegen einer Tür (1) sowie mit einem Notventil (17) versehen ist, mit dem beide Arbeitskammern (5 und 6) des die Tür (1) bewegenden Arbeitszylinders (4) drucklos gemacht werden können, um die Tür (1) von Hand zu betätigen. Das Notventil (1) hat zwei Verriegelungen (20/21, 33/34), von denen die eine (20/21) mechanisch und die andere (33/34) elektromagnetisch betätigbar ist. Damit wird erreicht, daß zwar eine Umschaltung von Kraftbetrieb auf Handbetrieb in jeder Betriebslage der Tür bewirkbar ist, umgekehrt aber eine Umschaltung von Handbetrieb auf Kraftbetrieb nur möglich ist, wenn erst die mechanische Verriegelung (20/21) gelöst und dann durch Betätigen des Türventils (17) durch den Fahrer ein Stromkreis zum Aufheben der elektromagnetischen Verriegelung (33/34) geschlossen wird. Ein Einklemmen im Türbereich durch Betätigen des Nothahns (17) von außen durch die offene Tür (1) hindurch ist damit ausgeschlossen.