baber/WOPTO huggingface dataset:
Patent RU-2366655-C2 (RU)
Inventor: NISIZAVA RENA
IPC: A61K31/4468
Filed: 2004-03-12
Granted: 2009-09-10
Abstract: FIELD: chemistry. 
     SUBSTANCE: present invention refers to the new compounds of formula (I):   whereat R 1  is -SO 2 NR 102 R 103 , -NR 101 SO 2 R 104  or -COOR 105  whereat R 101  is hydrogen atom, R 102  and R 103  each independently represents hydrogen atom or C1-4 alkyl, R 104  is C1-4 alkyl and R 105  is hydrogen atom or C1-4 alkyl ; X is bond, -CH 2 - or -O-; Y is -CH 2 -; ring A and ring B, which are same or different, each independently is benzene, pyridine, pyrazol or piperidine which can have the following substituents: C1-4 alkyl or halogen; ring D is piperidine; R 2  is   whereat the arrow shows the position of the bond with the ring D; R 51  is (1) hydrogen atom a, (2) C1-6alkyl, which can have the following substituents: (a) hydroxy, (b) methoxy, (c) cyano, (d) carboxy, (e) halogen, (f) methyl sulphonylamino, (g) C3-8cycloalkyl or phenyl, which can have the following substituents: methyl, halogen, hydroxy or methoxy, (h) thienyl, pyrazolyl, tetrahydropyranyl, thiazolyl, isooxalyl, imidazolyl, tetraazolyl, pyridyl, pyrimidinyl which can have the following substituents: methyl, trifluoromethyl or hydroxy, (3) C2-10alkenyl, (4) C2-10alkynyl, (5) phenyl which can have the following substituents: C1-4alkyl or halogen, or (6) pyridine or tetrahydropyran; R 52  is (1) hydrogen atom a, (2) C1-6alkyl which can have the following substituents: (a) hydroxy, (b) methoxy, (c) carboxy, (d) C3-8cycloalkyl, (e) phenyl or (f) oxo, (3) C3-8cycloalkyl or phenyl which can have the following substituents: C1-4alkyl, hydroxy, cyano, oxo, carbamoyl, N-methyl aminocarbonyl, carboxy, halogen, methoxy, trifluoromethoxy, methythio, methylsulphonyl, acetylamino, dimethylamino, acetyl, tetraazolyl, trifluoromethyl or methylsulphonylamino (4) C3-10cycloalkenyl, (5) adamantyl, (6) thienyl, pyrazolyl, tetrahydropyranyl, isoxaazolyl, isothiazolyl, thiadiazolyl, piperidinyl, pyridyl, pyrimidinyl, pyridazinyl, quinolyl, indolyl, benzothiazolyl, benzoisothiazolyl, benzotriazolyl, dioxaindanyl, benzodioxaindanyl which can have the following substituents: C1-4alkyl, hydroxy, oxo, halogen, azido or trifluoromethyl or (7) benzyloxy groups; and R 53  is hydrogen atom or C1-6alkyl; to its salts or its solvates. The invention refers also to the regulator CCR5, to the agent of prevention and/or treatment of HIV infection, immunological or inflammatory diseases, to the pharmaceutical composition, to the medicinal preparation, to the method of disease treatment or prevention as well as to the application of compound as in claim 1. 
     EFFECT: obtaining of new bioactive compounds possessing anti CCR5 receptor activity. 
     23 cl, 41 ex
Patent RU-2338059-C2 (RU)
Inventor: BAKANOV JURIJ IVANOVICH
IPC: E21B43/16
Filed: 2005-12-05
Granted: 2008-11-10
Abstract: FIELD: oil and gas industry. 
     SUBSTANCE: invention refers to oil and gas industry, particularly to methods of development of multibed oil deposits. Method includes selection of objects for operation, boring of producing and pressure wells for selected objects, pumping of displacement agent into pressure wells and oil withdrawal from producing wells. According to the invention operational objects -well cells- are selected assuming development of all beds of geological cross-section. Then the value of output of a cell of wells is determined and a version of integration of beds into selected operational object of development is established. At that complete separation of beds into independent objects, integration of all beds into one object of development and integration of part of beds are considered. For each of considered version the value of output is determined on base of different analytic formulas. After that the optimal version of separation of beds into independent object of development is chosen on criterion of facilitating maximum value of cell output of the well and minimal development duration at successive bringing of objects into development from bottom-up. 
     EFFECT: facilitating maximum oil extraction at minimal costs of capital investments and current costs. 
     2 cl, 1 tbl
Patent RU-2304547-C2 (RU)
Inventor: SMETANNIKOV VALERIJ IL ICH
IPC: B64D1/08
Filed: 2003-06-25
Granted: 2007-08-20
Abstract: FIELD: devices for arrangement of cargoes in aircraft and landing them. 
     SUBSTANCE: proposed device is provided with unit for increase of volume of pallet accumulator reservoir, unit for locking the pallets before landing position in form of elastic rod located along aircraft longitudinal axis. Joint of one end of this rod is located in front section of cargo compartment and joint of other end is located behind bend of rod in front of landing position in rear section of cargo compartment. Rod is provided with freely moving rings used for connecting it with pallets. 
     EFFECT: ease of locking the pallets. 
     5 cl, 12 dwg
Patent RU-2343026-C2 (RU)
Inventor: TARTAKOVSKIJ IGOR KONSTANTINOVICH
IPC: B21B19/04
Filed: 2006-01-10
Granted: 2009-01-10
Abstract: FIELD: technological processes. 
     SUBSTANCE: tube-rolling plant contains heating furnace, helical primary mill, helical piercing mill and transmitting devices. Problem is solved by the fact that axis of helical primary mill is installed at an angle to axis of helical piercing mill, at that transmitting devices from heating furnace to primary mill and from primary mill to piercing mill, installed at the right angle to roller table that connects heating furnace with piercing mill, are equipped with rotary tables, turn angle of which is equal to angle of primary mill axis location to axis of piercing mill. 
     EFFECT: expansion of technological resources of tube-rolling plant with provision of high-quality cartridges. 
     1 dwg
Patent RU-2315635-C2 (RU)
IPC: A61M21/00
Filed: 2006-02-27
Granted: 2008-01-27
Abstract: FIELD: medicine. 
     SUBSTANCE: method involves asking patient to listen to phonograms. Musical compositions rhythm and tempo are digitally expressed as the number of accented sounds or strikes per 1 min of musical composition playback. Patient listens to sounds representing heart work on the background of the musical composition playback and tries to integrate heart beat rhythm into the melody tempo he is listening to. Tachycardia and arrhythmia being available, musical rhythm therapy is started under condition that musical composition playback index corresponds to initial patient heart beat rate and continued to arrhythmia reduction moment. Then, the musical composition playback index is reduced by 4 units every following musical composition and the sessions are continued to the moment normal heart beat rate values are reached. Bradycardia and arrhythmia being available, musical rhythm therapy is started under condition that that musical composition playback index corresponds to initial patient heart beat rate and continues to arrhythmia reduction moment. Then, the musical composition playback index is increased by 4 units every following musical composition and the sessions are continued to the moment normal heart beat rate values are reached. Extrasystolia under normal heart beat rate being the case, therapy session is started when musical composition playback index corresponds to initial patient heart beat rate and continued to extrasystolia reduction moment. Musical composition tempos increasing heart beat rate are selected for bradycardia patients. Tachycardia patients are treated with musical composition tempos reducing heart beat rate. 
     EFFECT: enhanced effectiveness in normalizing heart beat rate and arterial blood pressure; enhanced effectiveness in treating patients having contraindications against commonly applied drug therapy; enabled cardiovascular system self-control at home.
Patent RU-2371195-C2 (RU)
Title: Method of virus infection treatment
Inventor: SMIT GOVARD DZH
IPC: A61P31/12
Filed: 2004-08-03
Granted: 2009-10-27
Abstract: FIELD: medicine. ^ SUBSTANCE: invention claims method of virus infection treatment in case of main tissue damage and main virus replication point located in liver (versions), relevant kit and combination. Method involves combined injection of therapeutically effective amount of interferon and riboflavin, with riboflavin administered in slow-release composition in daily dosage under 400 mg to maintain clinically effective ribavirin level in portal vein blood stream and in lower amount than required to reach clinically effective level in peripheral circulation. Method maintains clinically effective interferon level in portal system blood stream, yet it is lower than in peripheral circulation, and therefore maintains systemic interferon effect on the whole organism and selective ribavirin action in liver. Kit and combination can include andioxidiser or other membrane-stabilising medium. ^ EFFECT: stable virological effect for patient, reduced side effects. ^ 30 cl, 2 ex
Patent RU-2361644-C2 (RU)
Title: Способ разделения твердой и жидкой фаз
Inventor: UILSAK RICHARD A
IPC: C07C7/00
Filed: 2004-08-04
Granted: 2009-07-20
Abstract: Настоящее изобретение относится к способам отделения жидкости от твердых частиц в шламе. Способ отделения твердых частиц от жидкостей осуществляют в зоне фильтрации, состоящей из зоны повышенной концентрации и зоны пониженной концентрации, отделенных фильтром. Способ включает этапы направления шлама, содержащего жидкость и твердое тело, в зону повышенной концентрации, направления вытесняющей текучей среды в зону повышенной концентрации в противоположном направлении потоку шлама и прохождения, по крайней мере, части жидкости через фильтр в зону фильтрации с образованием фильтрата. При этом вытесняющая текучая среда нерастворима в компонентах шлама и в качестве вытесняющей текучей среды используется либо жидкость, либо газ. Шлам включает продукт кристаллизации, например, параксилол. Способ осуществляют в фильтрационной колонне, которая включает полый цилиндр и, по крайней мере, одну фильтрационную трубу. Труба расположена внутри цилиндра и вытянута в осевом направлении. Труба включает присоединенный к ней фильтр, который образует прямое соединение между внутренней частью трубы и внутренней частью полого цилиндра. Способ позволяет эффективно отделять твердые продукты от шлама, предусматривает возможность изменения чистоты твердого продукта, позволяет снизить капитальные затраты на оборудование и его обслуживание. 4 н. и 40 з.п. ф-лы, 1 табл., 2 ил.
Patent RU-2330012-C2 (RU)
Title: Method of obtaining aryl ethers
Inventor: TSEBULA MATEUSH
IPC: C07C217/62
Filed: 2005-02-08
Granted: 2008-07-27
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to the method of obtaining the compound of the formula (IV)  , which includes the epoxidation of the compound of the formula (I)   the agent of oxidation in the presence of optically active compound with the formation of the compound of formula (II)  , adding the gent to break the reaction, in order to extinguish any surplus oxidising agent present, where the agents for breaking the reaction are tri(C 1 -C 6 )alkylphosphite; without the isolation of the compound of the formula (II), the interaction of the reaction mixture, which includes the compound of the formula (III)   in the presence of the base and the cleaning of the compound of the formula (IV) by crystallisation. The invention also relates to the method of obtaining the compound of the formula (IX)  , which includes the reaction of the compound of formula (IV) with a silylation agent with the formation of a compound of the formula (V)  ; the reaction of the compound of formula (V) with the silylation agent of the formula R'SO 2 X, where R' represents the remainder of sulfonic acid (C 1 -C 6 ) alkyl and the X represents the detached group, with the obtaining of the compound of formula (VII)  ; the substitution of the sulphonyloxy-group with the obtaining of the compound of the formula (VIII)   and reaction of the compound of the formula (VIII) with ammonia or a compound of ammonia obtaining a compound of the formula (IX). The invention also relates to the intermediate compounds (V) and (VI)   The compound of the formula (IX) can be used for obtaining a biologically active material - (S, S) - reboxetin.    . In the given structural formulas pit independently are equal to 0 or a whole number from 1 up to 5; each of the groups R and R 1 , which can be identical or different, represents C 1 -C 6  alkoxy or C 1 -C 6  alkyl; P represents the protective group; R' represents the remainder of sulfonic acid (C 1 -C 6 ) alkyl. 
     EFFECT: obtaining aril ethers. 
     14 cl, 5 ex
Patent RU-2336859-C2 (RU)
Inventor: KONTOROVICH MIKHAIL BORISOVICH
IPC: A61H31/02
Filed: 2006-10-18
Granted: 2008-10-27
Abstract: FIELD: medicine. 
     SUBSTANCE: invention relates to medicine and can be made used of in anesthesiology and critical care medicine, in particular for provision of biomechanics monitoring of breath and gas mixture composition in the process of jet pulmonary ventilation. Parameters of breath mechanism and the gas mixture composition are measured together with estimated result in accordance with physiologic norms. Respiratory support is also implemented, as well as a pause during 3-6 seconds, the beginning of which is chosen in arbitrary respiratory cycle simalteneousle with termination of the inhale phase and the beginning of the exhale phase 0.1-0.2 seconds prior the pause termination the measurement of alveolar pressure and carbonic acid and oxygen content are implemented. The ventilation is implemented with the frequency of 60-300 cycles a minute and turbulent current with the speed above 5 m/second. 
     EFFECT: provision of respiratory support parameters control registration. 
     5 dwg
Patent RU-2380227-C2 (RU)
Title: Армирование полимерных изделий при помощи ориентированных полос
Inventor: DEKHENNAU KLOD
IPC: B29C48/21
Filed: 2005-04-26
Granted: 2010-01-27
Abstract: Способ изготовления многослойного полимерного изделия, представляющего собой полый полимерный элемент и включающего, по крайней мере, один армирующий слой, состоящий из ориентированного полимера, и, по крайней мере, один основной слой полимера, находящийся в непосредственном контакте с, по крайней мере, частью армирующего слоя, в котором полимер основного слоя совместим с ориентированным полимером армирующего слоя и имеет такую же температуру плавления. Способ включает следующие шаги: (а) нанесение основного слоя полимера в виде струи расплавленного полимера на, по крайней мере, часть поверхности армирующего слоя и (в) отверждение расплавленного полимера на поверхности армирующего слоя путем быстрого охлаждения, при этом армирующий слой накладывают путем навивки упрочненной полимерной ленты, состоящей из ориентированного полимера, вокруг полого полимерного элемента, а основной слой полимера накладывается поверх армирующего слоя. Технический результат, который обеспечивается при использовании способа по изобретению, заключается в исключении значительного нарушения волокнистой структуры внутри ориентированного полимера за счет приведения в непосредственный контакт твердого слоя ориентированного полимера с потоком расплавленного полимера, если последний подвергается быстрому охлаждению. 5 з.п. ф-лы.
Patent RU-2353720-C2 (RU)
Inventor: LEVAKOVA NATALIJA MARKOVNA
IPC: D03D15/217
Filed: 2007-05-24
Granted: 2009-04-27
Abstract: FIELD: textiles; paper. 
     SUBSTANCE: proposed fibre is meant for use as decorative-upholstery material for interior of public buildings, institutions and transport. The decorative fibre with low inflammability Decor M is made from fireproofed polyester threads or yarn and contains a combustible component, chosen from a group of cotton, viscose, linen fibre or their mixture. The ratio of the incombustible and combustible components in the fabric equals 20:80- 80:20 respectively, and the surface density of the fibre is 160-350 g/m 2 . The fabric is also impregnated with an aqueous solution of an ammonium salt of phosphonic acid with concentration 100-120 g/l. 
     EFFECT: designing an optimum structure of the fibre, providing for combining high fireproof properties, reduced static characteristics, peeling property, shrinking property, improved hygroscopic property and resistance to contamination. 
     2 cl, 1 tbl
Patent RU-2387595-C2 (RU)
Inventor: ROZHKOV ALEKSEJ ALEKSANDROVICH
IPC: B66B19/02
Filed: 2008-03-04
Granted: 2010-04-27
Abstract: FIELD: transport. 
     SUBSTANCE: when the method is implemented cage position is fixed on the first guides by catchers and counterweight position is fixed relative to the second guides. End connections of at least one old tracking cable on counterweight beam and on the cage are dismantled. End connections of at least one new cable on the counterweight beam and the cage are mounted. Counterweight is fixed relative to the second guides by the first old tracking cable on traction sheave of lever hoist while dismantling connection with cage of one end of this old cable and mounting its connection on the same cable fixed on counterweight beam. After that connection of one end of the second old tracking cable on the cage and connection of the other end of this old tracking cable with counterweight beam is dismantled and the second old tracking cable is connected with corresponding end of the new cable to replace this old tracking cable. 
     EFFECT: improvement of operational comfort for electricians and decrease in labour consumption. 
     5 cl, 8 dwg
Patent RU-2412902-C2 (RU)
Inventor: KVARATSKHELI JURIJ KONSTANTINOVICH
IPC: C01B33/04
Filed: 2008-03-21
Granted: 2011-02-27
Abstract: FIELD: process engineering. 
     SUBSTANCE: invention may be used in production of semiconductors, microelectronics and solar power engineering. Proposed method comprises interaction of calcium hydride with gaseous silicon tetra fluoride in eutectic melt of lithium and potassium chlorides at 360-390°C and purification of monosilane on granulated sodium fluoride, zeolite and carbon. Proposed device comprises thermal reactor 19 with melt 12 of potassium and lithium chlorides, appliances for feeding gaseous silicon tetra fluoride into melt 1 and withdrawing monosilane from reaction zone 11. To maintain concentration of calcium chloride in melt 12 at saturation level, tight thermal tank 18 with calcium hydride is arranged above reactor 19. Said tank is provided with branch pipe that terminates in reticulate vessel 13. Boundary between said vessel and branch pipe is located below melt level 12 in reactor 19. To maintain the level of melt 12 in reactor 19, tight thermal tank 17 with melt is arranged above the reactor. Said tank is furnished with branch pipe with its lower end lowered in tank 18 to preset level. To discharge calcium fluoride, reactor bottom is provided with settling device 20 that incorporates two valves or gates interconnected so that on opening top valve, bottom valve is closed, and visa versa. 
     EFFECT: efficient process. 
     5 cl, 2 dwg
Patent RU-2388450-C2 (RU)
Inventor: FURIN VLADIMIR FEDOROVICH
IPC: A61H15/00
Filed: 2008-04-07
Granted: 2010-05-10
Abstract: FIELD: medicine. 
     SUBSTANCE: claimed group of inventions relates to sporting and medical equipment, in particular to devices for health-improving, prophylactic, as well as stimulating massage. Massage head consists of disk, on which placed are work elements, and disk is rigidly connected with handle with diametre from 30 to 50 mm and with length equal to disk diametre for performing massage by reciprocating rotary movements of head. According to second version of implementation massage head consists of disk, on which fastened are work elements, is placed on axis of device for massage with reciprocating rotary movements for performing massage. 
     EFFECT: ensuring deep massage of muscular tissues, tension and pressing of skin, possibility to perform massage through clothes, as well as treatment of osteochondrosis. 
     22 cl, 6 dwg
Patent RU-2395222-C2 (RU)
Title: Обувь
Inventor: KARANDONIS DZHON FOTIS
IPC: A43B11/00
Filed: 2005-11-21
Granted: 2010-07-27
Abstract: Заявленная группа изобретений относится к конструкции ботинка, способу надевания ботинка на ногу человека за счет особенностей конструкции ботинка по изобретению и способу снятия ботинка с ноги человека. Ботинок (1) имеет носочную часть (2) и пяточную часть (3), которая может полностью или частично отсоединяться от носочной части (2). Ботинок с по существу гибким верхом и по существу твердой подошвой содержит носочную часть, включающую переднюю часть подошвы и переднюю часть верха, пяточную часть (3), включающую заднюю часть подошвы и заднюю часть верха. При этом пяточная часть (3) может по меньшей мере частично отсоединяться от носочной части и поворачиваться относительно нее, позволяя вставлять стопу в носочную часть (2). Он имеет также разъединяемое крепежное средство (4) для соединения пяточной части с носочной частью с возможностью их отсоединения друг от друга и цельную стельку, которая прикреплена к носочной части с возможностью наложения на переднюю и заднюю части подошвы ботинка. Когда пяточная часть (3) по меньшей мере частично отсоединена от носочной части (2), ботинок можно легко надеть на ногу человека, которому не нужно сгибать стопу или прилагать усилие для надевания или снятия ботинка. В вариантах с частичным отсоединением пяточной части (3) ее можно повернуть относительно носочной части (2) вбок или вниз. Разъединяемое крепежное средство (4) может представлять собой молнию, Веклро (Velcro™) или другое средство. Технический результат, который будет достигаться при использовании обуви по изобретению, заключается в возможности частичного отделения разных частей обуви одну от другой, при этом обувь можно будет удобнее надевать и снимать без необходимости поворачивать стопу ноги и прилагать к ней усилие или давление. 3 н. и 5 з.п. ф-лы, 16 ил.
Patent RU-2414633-C2 (RU)
Inventor: VOL CHENKO ALEKSANDR IVANOVICH
IPC: F16D65/813
Filed: 2009-01-16
Granted: 2011-03-20
Abstract: FIELD: machine building. 
     SUBSTANCE: combined brake consists of lifting shaft and of inductor. A drum of a hoist with brake pulleys brake belts with friction straps are mounted on the lifting shaft. The inductor has teeth with different poles, a stator with an exciting coil and cooling system, and also mechanical and electrical drives. The rotor of the inductor brake corresponds to a pulley, the projection of which is magnet-insulated by means of padding from a flange of the drum. Rectangular teeth are arranged on internal surface of the pulley along ends of its perimetre with a gap between rows. The rows of the teeth function as poles of different polarity. The stator of the inductor brake is made as a square coil of excitation is cross section. It is positioned in the gap between the rows of the teeth and below ends of their heads. Also, axis of the coil is perpendicular to axis of rotor rotation. The coil is encased into a cooling jacket mounted on a stationary cylinder circular lug of the flange resting on a setting foot. 
     EFFECT: increased braking moment and its automatic control due to conductor brake facilitating shoe brake unloading and stable operation of its friction units. 
     2 cl, 3 dwg
Patent RU-2450804-C2 (RU)
Title: КОМБИНИРОВАННОЕ ФАРМАЦЕВТИЧЕСКОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО С КОНТРОЛИРУЕМЫМ ВЫСВОБОЖДЕНИЕМ, СОДЕРЖАЩЕЕ ДИГИДРОПИРИДИНОВЫЕ БЛОКАТОРЫ КАЛЬЦИЕВЫХ КАНАЛОВ И ИНГИБИТОРЫ HMG-CоА-РЕДУКТАЗЫ
Inventor: KIM SUNG VUK
IPC: A61K9/22
Filed: 2007-08-24
Granted: 2012-05-20
Abstract: Изобретение относится к медицине и может быть использовано для лечения больных с гипертензией и нарушением липидного обмена. Применяют комбинированное лекарственное средство, включающее дигидропиридин, блокатор кальциевых каналов, и статин, гиполипидемическое средство. Лекарственное средство получают таким образом, что скорость высвобождения указанных выше ингредиентов друг относительно друга может контролироваться. Способ позволяет повысить эффективность и комплаентность лечения, предотвратить антагонистические и побочные эффекты сочетанной терапии. 26 з.п.ф-лы., 12 табл., 10 ил., 19 пр.