baber/WOPTO huggingface dataset:
Patent WO-2019204721-A1 (WO)
Title: Chromatography column qualification in manufacturing methods for produring anti-tnf antibody compositions
Inventor: RANDOLPH PAUL
IPC: A61K38/00
Filed: 2019-04-19
Abstract: The present disclosure is directed to a method of operating a chromatography column in methods of manufacture for producing anti-TNF antibodies, e.g., the anti-TNFa antibody SIMPONI® (golimumab), and specific pharmaceutical compositions of the antibody. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is determined based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. The height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value. If during routine column monitoring, an adverse trend in HETP is observed or the control limits are exceeded, the eluate product quality, column process performance, and/or impurity removal data should be evaluated to ensure product quality for the identified batch. Should any of the product quality or column performance fail the criteria set, appropriate corrective action, such as conditioning, repacking or replacing the column, and qualification should be performed prior to release for further use.
Patent WO-2019217665-A1 (WO)
Title: Iron-acquisition receptor peptide administration for vaccination against pseudomonas aeruginosa
Inventor: BARBIER MARIETTE
IPC: A61K39/02
Filed: 2019-05-09
Abstract: A vaccine composition including an outer membrane protein of  P. aeruginosa , wherein the outer membrane protein is an iron acquisition receptor protein and a method of preventing a  P. 
 aeruginosa  infection involving administering the vaccine composition.
Patent WO-2019241492-A1 (WO)
Inventor: EMMERT JOHN T
IPC: G06Q10/04
Filed: 2019-06-13
Abstract: L'invention concerne des systèmes et des procédés pour obtenir un modèle empirique d'une atmosphère planétaire en fonction des variables indépendantes dans une formulation paramétrique. Des modes de réalisation de la présente invention peuvent représenter la température et des densités d'espèces individuelles de l'atmosphère planétaire dans la formulation, peuvent effectuer de manière robuste et efficace les calculs nécessaires pour évaluer cette formulation et pour estimer les paramètres de la formulation, et peuvent ainsi obtenir le modèle empirique de l'atmosphère planétaire.
Patent WO-2020005681-A1 (WO)
Title: A crystalline transition metal molybdotungstate
Inventor: MILLER STUART R
IPC: C01G39/06
Filed: 2019-06-20
Abstract: A hydroprocessing catalyst has been developed. The catalyst is a crystalline transition metal molybdotungstate material. The hydroprocessing using the crystalline ammonia transition metal molybdotungstate material may include hydrodenitrification, hydrodesulfurization, hydrodemetallation, hydrodesilication, hydrodearomatization, hydroisomerization, hydrotreating, hydrofining, and hydrocracking.
Patent WO-2020005838-A1 (WO)
Title: Hybrid closed-loop multiple-input multiple-output and transparent diversity schemes
Inventor: HUANG YI
IPC: H04B7/0456
Filed: 2019-06-24
Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) having partially coherent antennas may be configured for simultaneous transmissions on groups of antennas. To achieve the benefits of simultaneous transmissions using groups of antenna that are partially coherent, without having the transmissions affect each other, the UE may apply a hybrid closed-loop multiple-input multiple-output (MIMO) scheme among each antenna in the antenna groups where phase coherence can be maintained. Following the hybrid closed-loop MIMO scheme, the UE may apply a transparent diversity scheme across each antenna of the groups. Alternatively, the UE may first apply the transparent diversity scheme and next apply the hybrid closed-loop MIMO scheme. By applying a hybrid closed-loop MIMO scheme, and a transparent diversity scheme, the UE may fully realize its resources and contribute to an improved spatial diversity for a MIMO system.
Patent WO-2020006185-A1 (WO)
Title: Amplifier with integrated gain slope equalizer
Inventor: MIEHLE KONRAD
IPC: H03F1/56
Filed: 2019-06-27
Abstract: The present disclosure describes systems and devices for gain slope equalization in a radio frequency (RF) amplifier (200). The RF amplifier (200) may include an input stage (210) for receiving an RF signal. In conjunction with the input stage (210), the RF amplifier (200) may incorporate an amplification stage (215) to amplify the RF signal. Coupled with the amplification stage (215) may be a transformer (220) including a first winding to receive the amplified RF signal, a second winding providing an RF output signal, and a resonator including a third winding that is coupled to the first and second windings. The resonator may be coupled to a circuit network which may be tuned to affect the resonance frequency and the gain slope of the RF output signal.
Patent WO-2020010238-A1 (WO)
Title: Laser processing hydrogel materials
Inventor: HILL KIMBERLY
IPC: A61F13/02
Filed: 2019-07-03
Abstract: A method of forming one or more perforations, holes, or capillaries in a hydrogel material, hydrocolloid material, hydrogel adhesive or silicone adhesive comprising directing a focal point of a laser beam to a surface of the material or adhesive at one or more locations to form one or more perforations, holes, or capillaries having a selected diameter. The perforated hydrogel material or adhesive can be used in wound care dressings, wearable sensors, or devices intended to contact living tissue. The perforated material or adhesive may also be provided in contact with an exudate holding mechanism such as an open cell foam material to further increase the exudate absorbance of the hydrogel or hydrocolloid wound care dressing.
Patent WO-2020014234-A1 (WO)
Title: Material phase with electrical lead
Inventor: NICHOLAS NOLAN W
IPC: B01D15/36
Filed: 2019-07-09
Abstract: A chromatograph is provided for identifying components of a mixture. Components are identified by different rates of adsorption and/or desorption with a material phase. In one embodiment, an electrical lead is connected to the material phase for supplying an electrical charge to the material phase. The electrical charge alters the rate of adsorption/desorption of the components with the material phase. In another embodiment, the material phase is disposed between two conductors with electrical leads connected to each of the conductors. A charge differential between the two conductors alters the rate of adsorption and/or desorption of components with the material phase.
Patent WO-2020018460-A1 (WO)
Title: Ceiling tiles
Inventor: KAUMP DONALD
IPC: F21S2/00
Filed: 2019-07-15
Abstract: A ceiling structure includes a suspended framework having a plurality of main runners and a plurality of cross runners interconnected to define an array of tile receiving openings, each of the plurality of main runners and the plurality of cross runners including a tile mating surface facing downward to define a mounting frame at each respective tile receiving opening, and a plurality of ceiling tiles positioned within the array of tile receiving openings, each of the plurality of ceiling tiles having a main body. The main body of the ceiling tile includes a base having a periphery, a plurality of magnets positioned at the periphery and sized and shaped to magnetically couple the ceiling tile within a respective one of the tile receiving openings, and a plurality of baffles coupled to the base, each baffle being spaced apart from the other. Related methods, systems, and ceiling tiles are also provided.
Patent WO-2020028136-A1 (WO)
Title: Three-dimensional lattice structures containing operating material, compositions comprising the same, and compositions and methods for making the same
Inventor: BROWN JAMES F
IPC: C09D183/12
Filed: 2019-07-25
Abstract: Chemical structures that define cells in which operating material can be held, as well as compositions that contain such chemical structures and operating material, compositions for use in making such compositions, and methods for making all of the above. Compositions for use in making such chemical structures, comprising nuclear moiety precursor compounds and elongated moiety precursor compounds. Lattice structures comprising nuclear moieties (analogous to nodes) and elongated moieties (analogous to connectors extending between nodes). Articles comprising one or more of such compositions. Also, a structure that comprises a lattice structure/operating material region (comprising at least a first lattice structure (comprising a plurality of nuclear moieties and a plurality of elongated moieties) and at least a first operating material) and at least a first additional region.
Patent WO-2020023897-A1 (WO)
Title: Stabilized compositions comprising leuco compounds
Inventor: QIN HAIHU
IPC: C08K5/00
Filed: 2019-07-26
Abstract: A composition comprising: (a) a leuco composition; and (b) a stabilizing amount of an antioxidant composition. The antioxidant composition comprises at least one sterically hindered phenol and at least one substituted diarylamine, and the mole ratio of the hindered phenol to the substituted diarylamine is greater than 1:1. In another embodiment, a composition comprises (a) a leuco composition and (b) an antioxidant composition.; and optionally (c) a solvent composition. The combined mass of the leuco compounds and antioxidants present in the composition is 10% or more of the total mass of the composition, and (b) the molar ratio of antioxidants present in the composition to leuco compounds present in the composition is greater than 1:1.
Patent WO-2020028749-A1 (WO)
Title: Methods and compositions for alphavirus vaccine
Inventor: FROLOVA ELENA I
IPC: G01N33/569
Filed: 2019-08-02
Abstract: The present invention provides an attenuated Old World alphavirus particle and methods of making same and using same as a vaccine and in gene therapy and immunotherapy methods.
Patent WO-2020041000-A1 (WO)
Title: Power controller for aircraft receptacles
Inventor: YILMAZ ARDA
IPC: H02J7/00
Filed: 2019-08-07
Abstract: A system for allocating power includes a plurality of receptacles and a power delivery controller communicatively coupled to the plurality of receptacles. The power delivery controller is to: detect a new connection to a first receptacle of the plurality of receptacles; receive a request from the first receptacle which would exceed an amount of uncommitted available power; request a device attached to a second receptacle of the plurality of receptacles reduce an amount of power being received from the second receptacle; and in response to detecting a reduction of power to the second receptacle, provide power to the first receptacle as indicated in the request.
Patent WO-2020112189-A1 (WO)
Title: Computer architecture for artificial image generation using auto-encoder
Inventor: KIM PETER
IPC: G06V10/774
Filed: 2019-08-23
Abstract: A computer architecture for artificial image generation is disclosed. According to some aspects, a computing machine receives a voxel model of a first set of objects different from a target object. The target object is to be recognized using an image recognizer. The computing machine generates, based on the voxel model, a set of TSB (target shadow background-mask) images of the first set of objects. The computing machine receives, at an auto-encoder, a set of real images of the first set of objects. The computing machine generates, using the auto-encoder, one or more artificial images of the target object based on the set of TSB images. The auto-encoder learns differences between the target object and the first set of objects. The computing machine provides, as output, the generated one or more artificial images of the target object.
Patent WO-2021040682-A1 (WO)
Title: Combination back rest and body board
Inventor: RAVAZ RADBEH
IPC: B63B35/79
Filed: 2019-08-24
Abstract: A combination back rest and body board includes a rigid, planar body board having an upper surface, a lower surface, a first side edge, a second side edge, a rounded first end and a pointed second end. The pointed second end facilitates inserting the body board into a ground surface when used as a back rest. The body board may be planar, have a concave upper surface, a convex lower surface or it may have both curved surfaces. The body board includes first and second strap attaching openings for use with an adjustable carrying strap. The body board includes first and second notches along the side edges shaped to accommodate the carrying straps of a back pack. The body board is marked with a depth indicator spaced from the pointed second end to indicate sufficient depth to insert the second end into a ground surface for secure back rest use.
Patent WO-2020051187-A1 (WO)
Inventor: NEWBURY KARSTEN
IPC: G06Q30/06
Filed: 2019-09-04
Abstract: La présente invention concerne un système de production de vêtements, qui comprend un environnement de développement virtuel et qui est configuré pour : recevoir et stocker, dans une base de données du système, des informations de corps concernant un utilisateur; établir des mesures pour l'utilisateur sur la base des informations de corps; afficher, sur un dispositif d'affichage connecté à l'environnement de développement virtuel, une représentation virtuelle de l'utilisateur à l'aide des mesures établies; personnaliser un ou plusieurs vêtements pour l'utilisateur sur la base des mesures établies; afficher, sur le dispositif d'affichage, une représentation virtuelle du ou des vêtements personnalisés sur la représentation virtuelle de l'utilisateur; recevoir et stocker dans la base de données des informations de personnification à partir de l'utilisateur regardant le ou les vêtements personnalisés; et modifier le ou les vêtements personnalisés et la représentation virtuelle de ceux-ci sur la base des informations de personnification reçues aux fins de leur fabrication.
Patent WO-2020072233-A1 (WO)
Title: Drug delivery device
Inventor: ARGERSINGER ANDREW
IPC: A61M5/14
Filed: 2019-09-24
Abstract: An infusion pump which may include a control unit and a pump engine may be used to facilitate administration of medicinal fluids to a patient. A control unit may include a motor, a controller, a housing, and a motor coupling, where the motor coupling includes two protruding motor coupling tabs extending in a direction parallel to an output shaft of the motor. A pump engine may include a housing, a rotor disposed in the housing, and a pump coupling, where the pump coupling includes at least two protruding pump coupling tabs extending in a direction parallel to an input shaft of the rotor. The controller may be configured to change an operational mode of the infusion pump, where when the infusion pump is in a positioning mode, the controller activates the motor to move the output shaft to a predetermined angular position.
Patent WO-2021061113-A1 (WO)
Title: Card retainers
Inventor: MA XIANG
IPC: H05K7/14
Filed: 2019-09-25
Abstract: In an example, a card retainer may include a pivot mount, a bracket, and a latch hook. The bracket may be movable or pivotable between a released position and a locked position. The bracket may include a bracket pivot, a locking portion, and a cantilevered latch. The locking portion may engage with an expansion card. Further, the cantilevered latch may engage with the latch hook to retain the bracket in the locked position.
Patent WO-2020159584-A1 (WO)
Inventor: OUYANG TIANMEI
IPC: A61B5/145
Filed: 2019-09-25
Abstract: Les taux de créatinine peuvent être surveillés en tant que mesure de la fonction rénale. De manière classique, des tests sanguins et/ou d'urine sont utilisés à cet effet. Des capteurs d'analyte capables de surveiller la créatinine in vivo peuvent comprendre : une queue de capteur comprenant au moins une première électrode de travail, une zone active sensible à la créatinine disposée sur une surface de la première électrode de travail, une première membrane qui est perméable à la créatinine et recouvre la zone active sensible à la créatinine, et un désoxygénant situé sur la queue de capteur à proximité de la zone active sensible à la créatinine. La zone active sensible à la créatinine comprend un premier agent de transfert d'électrons, un premier polymère et un système d'enzymes comprenant de multiples enzymes, en particulier la créatinine amidohydrolase, la créatine amidohydrolase et la sarcosine oxydase, qui sont capables d'agir conjointement pour faciliter la détection de créatinine. Une enzyme oxydase peut servir de désoxygénant, en particulier la glucose oxydase lors de la détection de créatinine dans des liquides contenant également du glucose.
Patent WO-2020069045-A1 (WO)
Title: Digital amplification for protein detection
Inventor: CHIU DANIEL T
IPC: C12Q1/68
Filed: 2019-09-25
Abstract: The present disclosure provides a method of measuring the quantity of analyte molecules. In some aspects, the method comprises compartmentalizing a sample with binding molecules conjugated to synthetic nucleic acid molecules such that the interaction of the binding molecules with the analyte molecules brings the nucleic acid molecules into proximity. Proximity triggers reactions that result in an optical signal, such as fluorescence, in analyte-containing compartments which can be counted to determine the quantity of analyte present.
Patent WO-2020072459-A1 (WO)
Inventor: CRISP ROBERT J
IPC: C12Q1/68
Filed: 2019-10-01
Abstract: L'invention concerne des procédés, des récipients d'échantillons et des instruments permettant de déterminer la résistance aux antibiotiques d'une bactérie.
Patent WO-2020076647-A1 (WO)
Inventor: NAMMI SAIRAMESH
IPC: H04L27/26
Filed: 2019-10-04
Abstract: The described technology is generally directed towards having a transmitter in a wireless network generate and map reference signal sequences (e.g., for demodulation or other reference signal usage) so that the reference signal sequences are non-repetitive in a resource block. Avoiding repetition of the reference signal sequences reduces the peak-to-average power ratio in orthogonal frequency-division multiplexing (OFDM) systems. In one aspect, a transmitter device generates different reference signal sequences to avoid repetition of resource signal sequences, and maps the different reference signal sequences to appropriate (different) resource elements of a resource block. In one implementation, the different reference signal sequences can be based on different indexes of antenna ports. In an alternative implementation, the different reference signal sequences can be based on different code division multiplexing groups.
Patent WO-2020101905-A1 (WO)
Inventor: VAN WIJK RUDOLF JOHANNES
IPC: H01F27/28
Filed: 2019-10-31
Abstract: According to one embodiment, a cooled transformer including: a laminated core comprising a first core extension and a second core extension; a first inner coil circumferentially wrapped around the first core extension; a first outer coil circumferentially wrapped around the first core extension; the first outer coil being located radially outward from the first inner coil; a second inner coil circumferentially wrapped around the second core extension; a second outer coil circumferentially wrapped around the second core extension; the second outer coil being located radially outward from the second inner coil; and at least one cooling plate interposed between the first inner coil and the first outer coil.
Patent WO-2020102002-A1 (WO)
Title: Oral hygiene tool
Inventor: LADVA SURESH KURJI
IPC: A61C17/00
Filed: 2019-11-07
Abstract: A oral hygiene tool (10) has a tongue scraper (34) and a toothbrush (28). The tongue scraper (34) includes an elongate connector body (22), a scraper blade (36) being on a first end (40) transverse to the elongate connector body (22). A slide control mechanism (44) extends from a second end (42) of the elongate connector body (22). An interlocking structure (54) has a laterally extending ridge (60). The toothbrush (28) includes an elongate toothbrush body (22) that has a plurality of brushes (28) and a bore (48) that extends into a distal end (26) of the elongate toothbrush body (22). A slot (56) extends longitudinally along part of the elongate toothbrush body (22) into the bore (48), while first and second lateral grooves (58 a & 58b) extend laterally into the slot (56). The interlocking structure (54) is adapted to be slidably inserted into the bore (48) of the elongate toothbrush body (22) such that the interlocking structure (54) is pushed outwardly into the slot (56) of the elongate toothbrush body (22).
Patent WO-2020102791-A1 (WO)
Inventor: KAPRE SUBHASH V
IPC: A61K39/145
Filed: 2019-11-18
Abstract: Cette invention concerne un système de plate-forme intégrée commandé par un matériel et un logiciel pour une fabrication locale juste-à-temps. Le matériel du système peut comprendre un système de fermentation, un système à flux transversal, un système de formulation jetable, un système de remplissage-finition robotique, et un système de test de contrôle de qualité et de libération.
Patent WO-2020117711-A1 (WO)
Inventor: VED AMBER
IPC: G06F21/62
Filed: 2019-12-02
Abstract: The disclosed computer-implemented method for controlling access to information stored in an information retention system may include (1) receiving, at a computing device, metadata associated with an object type of respective objects, where at least two of the respective objects are in different domains, (2) determining, from the metadata, the respective object types of at least two objects, (3) forming a hierarchy of the at least two objects based on relative features of the respective object types, and (4) performing a security action comprising (A) receiving at least one access rule controlling access by at least one user to the at least two objects and (B) storing, in at least one storage device in the information retention system, the at least one access rule, the hierarchy of the objects, and the at least two objects. Various other methods, systems, and computer-readable media are also disclosed.
Patent WO-2020123936-A1 (WO)
Inventor: JARJOUR JORDAN
IPC: C07K19/00
Filed: 2019-12-13
Abstract: La présente invention concerne des compositions améliorées pour des thérapies adoptives avec des lymphocytes T ciblant EGFR ou EGRFvIII pour le traitement, la prévention ou l'amélioration d'au moins un symptôme d'un cancer, d'une maladie infectieuse, d'une maladie auto-immune, d'une maladie inflammatoire et d'une immunodéficience, ou d'un état associé à celle-ci. La présente invention concerne des compositions améliorées pour des thérapies adoptives avec des lymphocytes T ciblant EGFR ou EGRFvIII pour le traitement, la prévention ou l'amélioration d'au moins un symptôme d'un cancer, d'une maladie infectieuse, d'une maladie auto-immune, d'une maladie inflammatoire et d'une immunodéficience, ou d'un état associé à celle-ci.