baber/WOPTO huggingface dataset:
Patent EA-002687-B1 (EA)
Title: Benzothiophene derivatives, use and composition thereof
Inventor: MONGE VEGA ANTONIO
IPC: C07D333/20
Filed: 1998-07-01
Abstract: 1. Benzothiophene derivative compounds of the general formula (I): where: Z is: -CO-, -CH(OR6)-, -C(NOR7)-; R1 is: H, C1-C6 alkyl, halogen, or -OR8; R2 and R3 are independently H, C1-C6 alkyl, halogen, -OR8, nitro, cyano, -NR9R10, -COR8, -CO2R8, -SO2NR9R10, -SO2R8, -SR8, -CONR9R10; R4 and R5 are the same or different and stand for: H, C1-C6 alkyl, halogen, haloalkyl, -OR8, nitro, -NR9R10, -COR8, -CO2R8, -SO2NR9R10, -SO2R8, -SR8, cyano, -CONR9R10, or R4 and R5 together form a benzene ring fused to the phenyl ring; R6 is H, C1-C6 alkyl, CO2R8, -C(O)NR9R10, naphthyl or phenyl optionally substituted by one or more substituents selected from H, haloalkyl, alkyl, halogen, C1-C6 alkoxy, methylenedioxy, nitro, cyano; R7 is H or C1-C6 alkyl; R8 is H, C1-C6 alkyl, or phenyl; R9 and R10 are independent and stand for H, C1-C6 alkyl or phenyl or R9 and R10, together with the atom of N to which they are attached, form a 5- or 6- membered ring in which there may optionally be an atom of N, O or S; or a salt or a solvate, or a geometric isomer or an optical isomer or polymorphs thereof. 2. The compounds of Claim 1, where Z is -CO-: 1-(benzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan- 1-one hydrochloride; 1-(3,5-dimethylbenzo[b]thiophen-2-yl)-3-[4-(2-methoxyphenyl)piperazin- 1-yl]propan-1-one hydrochloride; 1-(5-fluorobenzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl ]propan-1-one; 1-(5-chlorobenzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl ]propan-1-one hydrochloride; 3. The compounds of Claim 1, where Z is -CH(OR6)-: 1-(benzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan- 1-ol; 1-(benzo[b]thiophen-3-yl)-3-[4-(2-hydroxyphenyl)piperazin-1-yl]propan- 1-ol; 1-(3,5-dimethylbenzo[b]thiophen-2-yl)-3-[4-(2-methoxyphenyl)piperazin- 1-yl]propan-1-ol; 1-(3-methylbenzol[b]thiophen-2-yl)-3-[4-(2-hydroxyphenyl)piperazin-1-y l]propan-1-ol; 1-(5-chlorobenzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl ]propan-1-ol; 1-(5-fluorobenzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl ]propan-1-ol; 4. The compounds of Claim 1, where Z is -C(NOR7)-: 1-(benzo[b]thiophen-3-yl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan- 1-one oxime; 5. The use of a compound according to any one of Claims 1 to 4 for the preparation of a pharmaceutical composition for the treatment of neurological disorders. 6. The use of Claim 5, for the preparation of a pharmaceutical composition for the treatment of anxiety and/or depression. 7. A pharmaceutical composition comprising a compound according to one of Claims 1 to 4, in a therapeutically active amount for the treatment of anxiety and/or depression and an adequate amount of a carrier.
Patent EA-008302-B1 (EA)
Title: Use of antitumor indolopyrrolocarbazole derivatives and other anticancer agent in combination
Inventor: ARAKAWA HIROHARU
IPC: A61K33/243
Filed: 2002-09-30
Abstract: The present invention relates to a combination of pharmaceutical preparations which are simultaneously, separately, or successively administered in treatments for cancers. It comprises the following two separate preparations:* a pharmaceutical preparation comprising a pharmaceutically acceptable support or diluent and either at least one compound represented by the general formula [I]:wherein Rrepresents hydrogen;Rrepresents a group of formula:G represents a group of formula:wherein Rrepresents hydrogen, and Rrepresents hydroxyl; andXand Xrepresent hydroxyl bonded to the indolopyrrolocarbazole ring at the 2-position and at the 10-position, respectively,or a pharmaceutically acceptable salt of the compound and* a pharmaceutical preparation comprising in combination with a pharmaceutically acceptable support or diluent an anticancer agent selected from the group consisting of 5-fluorouracil, doxorubicin, etoposide, cisplatin, carboplatin, and campthotecin or a pharmaceutically acceptable salt thereof (wherein, if said composition contains the compound of general formula I and 5-fluorouracil, it may further contain leucovorin.).
Patent EA-008679-B1 (EA)
Title: Personal identification and contact location and timing
Inventor: ARNOUSE MICHAEL
IPC: G06F21/62
Filed: 2003-12-30
Abstract: A universal lightweight, easily carried memory identification card (8) records information and controls access to this information. The memory card includes a file system of electronic files on the card, which are automatically detected and recognized by selected authorized readers. The file system is organized so that stored electronic files appear in separate and distinct encrypted compartments in the card, so that only authorized preselected readers have access to particular compartments. Biometric identifying information (4) is imprinted in the card, so that no data can be transferred unless there is a biometric match between a reader and a person assigned to the card and who possesses the card. The separate compartments of the memory card may include a compartment containing medical, administrative or financial information relating to the assigned user of the card, wherein the information is accessed only by a preselected memory card reader having the unique pin code assigned to the compartment having the medical information. The memory identification card can also have a single chip Global Positioning System (GPS) to identify where the card is being used.
Patent EA-009855-B1 (EA)
Title: Bimetallic thermostat with printed circuit interposed between a sensitive thermostatic element and a relay
Inventor: SARTOR ADRIANA
IPC: H01H37/06
Filed: 2005-04-11
Abstract: A bimetallic thermostat with exchange contact is described comprising an external support covering (1) and an internal device (2) made up of a pierced base (3) provided with a packing (4) and with electric contacts (5, 15, 25, 35) with the outside, of a relay (8) electrically connected with said base (3) and of 'a sensitive thermostatic element (9) electrically connected with said relay (8). Said thermostat comprises in addition a printed circuit (7) interposed between the sensing element (9) and the relay (8).
Patent EA-014940-B1 (EA)
Title: Condensed imidazolo derivatives for the inhibition of aldosterone synthase and aromatase
Inventor: KSANDER GARY MICHAEL
IPC: C07D471/04
Filed: 2006-08-23
Abstract: The present invention provides a compound of formula (I):Said compound is inhibitor of aldosterone synthase and aromatase, and thus can be employed for the treatment of a disorder or disease mediated by aldosterone synthase or aromatase. Accordingly, the compound of formula I can be used in treatment of hypokalemia, hypertension, congestive heart failure, atrial fibrillation, renal failure, in particular, chronic renal failure, restenosis, atherosclerosis, syndrome X, obesity, nephropathy, post-myocardial infarction, coronary heart diseases, inflammation, increased formation of collagen, fibrosis such as cardiac or myocardiac fibrosis and remodeling following hypertension and endothelial dysfunction, gynecomastia, osteoporosis, prostate cancer, endometriosis, uterine fibroids, dysfunctional uterine bleeding, endometrial hyperplasia, polycystic ovarian disease, infertility, fibrocystic breast disease, breast cancer and fibrocystic mastopathy. Finally, the present invention also provides a pharmaceutical composition.
Patent EA-025600-B1 (EA)
Title: Process for carbonylation of ethylenically unsaturated compounds, catalyst system and bidentate ligand
Inventor: EASTHAM GRAHAM RONALD
IPC: B01J31/24
Filed: 2006-11-08
Abstract: A process for the carbonylation of ethylenically unsaturated compounds including vinyl esters and a process for the production of 3-hydroxy propanoate esters or acids. The process comprises reacting said compound with carbon monoxide in the presence of a source of hydroxyl groups and of a catalyst system. The catalyst system is obtainable by combining: (a) a metal of Group 8, 9 or 10, and (b) a bidentate ligand of general formula (I)where X, X, Q, A, R, B, Q, Xand Xare as defined in the claims.
Patent EA-015447-B1 (EA)
Title: Process for fabricating a set of accessories for heat-hydro-insulated pipeline
Inventor: ENTHONI KOSTA
IPC: B29C44/24
Filed: 2008-06-18
Abstract: The invention relates to machine building, in particular to a complex for fabricating a set of accessories for use in heat-hydro-insulated pipeline for transporting liquids in heating mains, in particular to systems of hot and cold-water supply. According to the invention the proposed complex comprises interconnected technological posts, forming at least two technological lines for fabricating a set of pipe-enclosures, bare pipes for fittings and couplings, Z and Π-shaped elements of pipelines, bridges, bends and branches and blanks for couplings and heat-hydro-insulated stop valves, a post for assembling a structure pipe in a pipe and a post for pouring heat-insulating mixture to be hardened. The inventive result is aimed at providing a uniform universal complex combining technological posts forming a common process of accessories fabrication for a heat-hydro-insulated pipeline, enhancing technological simplicity and efficiency of accessories fabrication due to fabricating thereof using the proposed universal complex comprising posts easily adapted to each definite accessory, the complex uses a universal equipment including a system of starting the technological lines. The invention provides reduction of heat losses due to better heat-insulation parameters, a structure assembly pipe in pipe using said complex, improving joint operation of a working pipe, heat insulation and hydro insulation resulting in accessories' operation reliability and also to a partial combination of functions of the technological posts providing them with an additional functions ensuring a high quality of hydro insulation made from low-pressure polyethylene.
Patent EA-014709-B1 (EA)
Title: A process for the manufacture of carbon disulphide
Inventor: MESTERS CAROLUS MATTHIAS ANNA MARIA
IPC: E21B43/16
Filed: 2007-05-14
Abstract: The invention provides a process for the manufacture of carbon disulphide comprising supplying a molecular oxygen-containing gas and a feedstock comprising a hydrocarbonaceous compound to a reaction zone containing a liquid elemental sulphur phase and reacting, in the liquid sulphur phase, at a temperature in the range of from 300 to 750°C, the hydrocarbonaceous compound with elemental sulphur to form carbon disulphide and hydrogen sulphide and oxidising at least part of the hydrogen sulphide formed to elemental sulphur and water. The invention further provides the use of a liquid stream comprising carbon disulphide, hydrogen sulphide and carbonyl sulphide obtainable such process for enhanced oil recovery.
Patent EA-016841-B1 (EA)
Title: A proppant and method for making same
Inventor: SMITH RUSSELL J
IPC: C04B38/00
Filed: 2007-07-09
Abstract: The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.
Patent EA-016688-B1 (EA)
Title: Method for surgical treatment of anal rectal fistula
Inventor: MUSAEV KHALEDDIN NOURUZ OGLY
IPC: A61B17/00
Filed: 2009-04-09
Abstract: The invention relates to medicine, in particular, to a method of hydropreparation of pararectal cellulose, and namely to surgery of anal rectal fistula and can be used in treating patients with anal rectal fistola of different aetiology. The essence of the invention is characterized in that the proposed method provides to use 1% of dioxidine in combination with 5% of novocaine in ratio 1:1 under local anesthetization by washing wounded surface in pararectal cellulose and preparation thereof, and parallel therein a low-intensive infra-red laser irradiation is performed.
Patent EA-018796-B1 (EA)
Title: Process for preparing 2-(2-pyridinylmethylsulfinyl)-1h-benzimidazoles
Inventor: ISKRA JERNEI
IPC: C07D401/12
Filed: 2008-08-29
Abstract: The present invention relates to a process for preparing 2-(2-pyridinylmethylsulfinyl)-1H-benzimidazoles by oxidizing a thioether precursor in the presence of trifluoroethanol.
Patent EA-019788-B1 (EA)
Title: Forage harvester with a conditioning unit movable between an operating position and a non operating position
Inventor: ENGEL MANFRED
IPC: A01D43/08
Filed: 2011-03-01
Abstract: A self-propelled forage harvester (10) is provided having a frame (12), a chopping drum (22), an accelerator (24) arranged downstream of the chopping drum (22) and a channel (48) between the chopping drum (22) and the accelerator (24). The channel (48) has a section (42) in which a conditioning unit (50) or a hollow shell (44) can be selectively inserted. The conditioning unit (50) and the hollow shell (44) are jointly supported on a pivot arm (62) pivotable by way of a displacement drive about a pivot axis running horizontally and transverse to the forward direction. The pivot arm (62) is movable between an operating position of the conditioning unit (50), in which the conditioning unit (50) is in the section (42), and a non-operating position of the conditioning unit (50), in which the shell (44) is in the section (42). The conditioning unit is mounted on the pivot arm rotatably about the pivot arm (62), about a second axis (66) parallel to the first pivot axis (64) and mounted on the pivot arm (62). The conditioning unit (50) cooperates with the frame (12) by way of a positive guide (70), so that the conditioning unit (50) rotates about second axis (66) in the same direction as the pivot arm (62) which rotates about the first pivot axis (64).
Patent EA-018400-B1 (EA)
Title: Device for secondary production reservoir exposing with mechanical treatment
Inventor: KUZYAEV ELMIR SATTAROVICH
IPC: E21B43/11
Filed: 2011-04-01
Abstract: The invention relates to gas and oil producing industry, in particular to devices used for secondary production reservoir exposing with mechanical treatment thereof. A device for secondary production reservoir exposing with mechanical treatment thereof comprises a body with a drive arranged therein for rotating and feeding a drilling means embodied as a frame with a flexible working member, a longitudinal guiding groove is made in the frame, the frame has a drive sprocket, the drilling means is kinematically connected to the drive, the body is provided with a mechanism for fixing to the borehole wall, wherein the drilling means is hinge fixed on the body, with a hydrosystem additionally arranged therein comprising a pump, a hydraulic cylinder with a spring-loaded rod, an overpressure valve and a capacity for oil, the pump is kinematically coupled with the drive and connected to the a hydraulic cylinder with a spring-loaded rod, which, via the overpressure valve is connected to the oil capacity, and the hydraulic cylinder rod is adapted to move in the frame groove. Rotation of the driving sprocket for moving the flexible working member and turn of the drilling means are carried out through a hydraulic drive or an electric drive, while a mechanism for fixing to the borehole wall is embodied as a hydraulic cylinder with a rod and a return spring. The inventive result is aimed at enhancing reliability due to the use of hydraulically controllable feed to a frame turn, providing safe removal of the drilling means from a borehole.
Patent EA-023194-B1 (EA)
Title: Variants of glucoamylase
Inventor: DEGN PETER EDVARD
IPC: C13K1/06
Filed: 2010-08-18
Abstract: The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
Patent EA-031192-B1 (EA)
Title: Method and system for iterative production process control
Inventor: HERBST HARALD
IPC: G05B17/02
Filed: 2011-06-21
Abstract: The present invention relates to a method for controlling and optimizing a production process of at least one of a material and a product formed out of the compound material. Thereby a production control unit is provided with three different parameter groups, namely redefined indicating parameters, nominal parameters and correcting parameters, wherein the indicating and nominal parameters may be selected out of a group comprising process parameters, material recipe parameters and product property parameters. The correcting parameters may be selected out of the group comprising process parameters and recipe parameters. As reference values, nominal parameters are provided to the production control unit. During a first production cycle at least one indicating parameter is measured and the measured values are provided to the unit. If the values deviate to much from the nominal parameters, the unit afterwards sets at least one correcting parameter on basis of the indicating parameter and on basis of the nominal parameter, thereby concerning any interaction between different parameters due to changes of any parameter.
Patent EA-022045-B1 (EA)
Title: Process for conversion of synthesis gas to higher hydrocarbons (variants)
Inventor: GAMLIN TIMOTHY DOUGLAS
IPC: C10G2/00
Filed: 2012-02-06
Abstract: A process for the conversion of synthesis gas to higher hydrocarbons by contacting a gaseous stream comprising synthesis gas with a particulate Fischer-Tropsch catalyst, said process being carried out in a tubular reactor having an inlet and an outlet, said outlet being located downstream of the inlet, said reactor comprising one or more tubes having located therein one or more carriers for said particulate catalyst and cooling medium in contact with said tubes; wherein said catalyst carrier comprises: an annular container for holding catalyst in use, said container having a perforated inner wall defining a tube, a perforated outer wall, a top surface closing the annular container and a bottom surface closing the annular container; a surface closing the bottom of said tube formed by the inner wall of the annular container; a skirt extending upwardly from the perforated outer wall of the annular container from a position at or near the bottom surface of said container to a position below the location of a seal; and a seal located at or near the top surface and extending from the container by a distance which extends beyond an outer surface of the skirt; said process comprising: (a) introducing the gaseous reactants through the inlet; (b) passing said reactants downwardly through said at least one tube to the upper surface of the, or the first catalyst carrier where they pass into the passage defined by the inner perforated wall of the container before passing radially through the catalyst bed towards the perforated outer wall; (c) allowing reaction to occur as the synthesis gas contacts the catalyst; (d) passing unreacted reactant and product out of the container though the perforated outer wall and then upwardly between the inner surface of the skirt and the outer wall of the annular container until they reach the seal where they are directed over the end of the skirt and caused to flow downwardly between the outer surface of the skirt and the inner surface of the reactor tube where heat transfer takes place; (e) repeating steps (b) to (d) at any subsequent catalyst carrier; and (f) removing product from the outlet.
Patent EA-023333-B1 (EA)
Title: Lock and key with double code pattern
Inventor: WIDEN BO
IPC: E05B27/10
Filed: 2011-09-21
Abstract: The invention relates to a lock and key combination including a cylinder lock with a rotatable key plug having a key slot for receiving a flat key blade (100) on a key, and at least two side locking tumblers (201a, 201b; 301, 302; 401, 402) which are guided in associated chambers in the key plug and have transverse fingers (211a, 211b; 311, 312; 411, 412a, 412b) projecting into the key slot. There is a code pattern (110) in a side recess (115, 118) of the key blade comprising at least two separate code surfaces formed on at least one side surface (101) of the key, including a primary code surface (131-135; 141'; 151) located in an external portion of the side recess and adjoining said one side surface (101), and a secondary code surface (141-145; 142'; 152) being defined in a groove forming a deeper portion of the side recess. The primary and secondary code surfaces engage with first and second fingers (211b, 311, 411 and 211a, 312, 412a) on associated side locking tumblers. Master key systems can be designed by using such locks and keys.
Patent EA-029840-B1 (EA)
Title: Improved expandable vinyl aromatic polymers
Inventor: URBANCZYK LAETITIA
IPC: C08J9/16
Filed: 2013-12-19
Abstract: The present invention is related to a composition comprising particles of an expandable vinyl aromatic polymer and platelet needle coke particles with a polymodal particle size distribution. The foams obtained from said expandable polymers prove a reduced thermal conductivity at a reduced foam density.
Patent EA-030130-B1 (EA)
Title: Compositions containing chondroitin sulphate and nattokinase for improving the bioavailability of chondroitin sulphate
Inventor: MIRAGLIA NICCOLO
IPC: C12P13/12
Filed: 2014-01-23
Abstract: The present invention describes combinations comprising chondroitin sulphate (CS) and nattokinase for the treatment and prevention of osteoarthritis and correlated acute and chronic inflammatory processes, or as nutraceutical compositions for the maintenance of musculoskeletal well-being in humans and animals. The characteristic of said combinations is that they increase the intestinal absorption of CS when administered orally. The effect of said combinations is exerted on a wide range of molecular weights of CS, including CS samples with very low molecular weights which already possess greater bioavailability than samples with a higher molecular weight. The effect is exerted on CS samples of any origin.
Patent EA-028994-B1 (EA)
Title: MINIATURE OPTICAL CELL BASED ON LIGHT-EMITTING DIODES OF 1600-5000 nm SPECTRAL RANGE
Inventor: ASTAKHOVA ANASTASIA PAVLOVNA
IPC: G01N21/3504
Filed: 2015-12-18
Abstract: The present invention is related generally to devices for measuring concentrations of gases in a medium being analyzed, in particular, to miniature optical cells for sensors of chemical substances. Proposed is a device measuring concentrations of gases in a medium being analyzed, comprising a casing that contains at least one LED emitter, a photodiode, an electronic unit designed for controlling at least one LED emitter, a photodiode preamplifier board connected to the electronic unit, and flat mirrors, wherein the casing has holes for analysed medium inlet, at least one LED emitter provides emission in a spectral range of 1600-5000 nm, the photodiode is spectrally matched to at least one LED emitter, and the flat mirrors are arranged so as to be capable of repeatedly changing the at least one LED emitter emission path and direction to the photodiode, the at least one LED emitter being mounted in the casing so that its position can be changed to adjust the length of the emission path from at least one LED emitter to the photodiode.
Patent EA-033271-B1 (EA)
Title: Sowing machine with multifunctional roller
Inventor: BERENDSEN MARK
IPC: A01C5/06
Filed: 2014-10-15
Abstract: Fertiliser drills and seed drills (13) mounted so as to swivel on drill arms (40) are arranged on the frame (6) of a pneumatic single-corn sowing machine, viewed in the direction of travel. A working implement designed as a roller (15) is located therebetween in order to reconsolidate the soil turned by the fertiliser drill (12), to precompress the soil between the working implement (14) and the seed drill (13), and to provide a depth guide for the single-corn sowing machine.