baber/WOPTO huggingface dataset:
Patent ES-543861-A0 (ES)
IPC: C12P19/14
Filed: 1985-06-04
Abstract: A process for enzymatically converting a polysaccharide to a monosaccharide or to one or more polysaccharides of lower molecular weight than the starting polysaccharide comprises contacting the polysaccharide at a pH of from 4.5 to 8.0 with an enzyme derived from Bacillus megaterium which exhibits alph-amylase activity. Preferably, the enzyme is derived from the strain of Bacillus megaterium deposited at the National Collection for Industrial Bacteria (NCIB) under the number 11568. Examples of polysaccharides which can be enzymatically converted according to this process includes starch, partial starch hydrolysates, pullulan and cyclodextrins.
Patent ES-544420-A0 (ES)
IPC: C07D401/14
Filed: 1985-06-21
Abstract: Novel racemates or optically active forms of 2-amino-4-hydroxy-3-quinoline carboxylic acid derivatives of the formula    <IMAGE>  I  wherein X is in the 5-, 6-, 7- or 8-position and is selected from the group consisting of hydrogen, halogen, alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF3-, CF3S- and CF3O-, R1 is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms, R2 is selected from the group consisting of (a) thiazolyl, 4,5-dihydrothiazolyl, pyridinyl, oxazolyl, isoxazolyl, imidazolyl, pyrimidyl and tetrazolyl, each optionally substituted with alkyl of 1 to 4 carbon atoms and (b) phenyl optionally substituted with at least one member of the group consisting of hydroxy, alkyl and alkoxy of 1 to 4 carbon atoms, CF3-, -NO2 and halogen, R3 is selected from the group consisting of 2-pyrrolidinyl of the formula   <IMAGE>  R4 is selected from the group consisting of hydrogen, an amino protective group and   <IMAGE> R'4 is selected from the group consisting of alkyl 1 to 5 carbon atoms optionally substituted with amino or protected amino, aryl and aralkyl, R5 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, aryl, aralkyl, p-hydroxy-benzyl, lH-indol-3-yl methyl of the formula   <IMAGE>  and -CH2SH, the last three being optionally protected by a blocking group and their non-toxic, pharmaceutically acceptable acid addition salts having analgesic and anti-inflammatory activity and novel intermediates.
Patent FI-851102-A0 (FI)
Inventor: SIEGEL HERBERT
IPC: C07D233/60
Filed: 1985-03-20
Abstract: N-Bicycloheptyl- and N-bicycloheptenyl-imidazoles of the formula I <IMAGE>  I  in which A, B, R1, R2 and n have the indicated meanings, and their physiologically tolerated salts, a process for the preparation of these compounds, pharmaceutical products based on these compounds, and their use as medicaments, in particular for the treatment of disturbances of the serum lipoprotein spectrum, are the subject-matter of the invention.
Patent FI-863392-A0 (FI)
Inventor: EK KURT LENNART
IPC: A23L7/157
Filed: 1986-08-22
Abstract: A process for the production of a crumb coating characterised in that a layer of liquid batter is formed on a heated surface, dried on the heated surface in such a way that it forms a coherent sheet, which sheet is detached from the heated surface, deep-fat fried, dried and finally milled to give crumbs of the desired particle size.
Patent FI-880751-A0 (FI)
Inventor: BAINES DAVID ALLAN
IPC: A01N63/10
Filed: 1988-02-17
Abstract: A repellent composition e.g. for repelling deer comprises a synthetic blend of components which are characteristic of the acid fraction obtained by a Soxhlet extraction of lion faeces followed by separation into basic, neutral and acid fractions; and felinine. The composition may comprise saturated alkanoic acids with carbon atoms in the range of 3-20; saturated aliphatic alcohols with carbon atoms in the range 14-16; various compounds containing primary or secondary amino groups and having carbon atoms in the range 3-9; a fermented egg product; a bittering agent and an adhesive agent.
Patent FI-883670-A0 (FI)
Inventor: FUKAZAWA KAZUO
IPC: H03K5/00
Filed: 1988-08-05
Abstract: A television receiver includes a phase-locked loop (PLL) (226-232) which generates a clock signal (CLK) having a frequency of N times the line frequency and being phase-locked to the horizontal line synchronizing signal (HSYNC). The clock signal produced by this PLL has a frequency which tends to jitter between N+1 and N-1 times the line frequency. To compensate for this jittering in the frequency of the clock signal, phase alignment circuitry (236) is coupled to the PLL to align the phase of the clock signal to the horizontal drive signal (HD) produced by the PLL on the occurrence of each horizontal drive pulse. The PLL may also include a delay element (234) which delays the horizontal drive signal applied to the phase comparator of the PLL. This delay element effectively advances the phase of the horizontal drive signal and the line-locked clock signal with respect to the horizontal sync signal to compensate for signal processing delays imparted in the generation of the horizontal drive signal and the clock signal.
Patent FI-895077-A0 (FI)
Inventor: GOEBEL ROLAND
IPC: A61K6/884
Filed: 1989-10-25
Abstract: Dental metal/synthetic resin composite articles which adhere strongly, are resilient and stable to moisture can be prepared from dental alloys and synthetic resins when an adhesion-promoter layer which displays a concentration gradient and is composed of silicon dioxide and metal oxide, especially chromium oxide, is arranged between them.
Patent FI-905268-A0 (FI)
Inventor: JAERVENKYLAE JONI
IPC: F16L9/128
Filed: 1990-10-25
Abstract: The invention concerns a method of manufacturing a pipe section (1), at least a part of the outer surface of which is ribbed, by extruding plastic or another thermoplastic material and a pipe section (1) manufactured in this manner as well as a joint between two pipe sections. To provide a thin-walled pipe section (1) the material is extruded into a mould by using as extrusion point the mould point corresponding to a rib (15) situated in the middle area of the pipe section (1). <IMAGE>
Patent FI-911000-A0 (FI)
Inventor: MOELLER ANDERS
IPC: A61B6/00
Filed: 1991-02-28
Abstract: PCT No. PCT/SE89/00478 Sec. 371 Date Feb. 28, 1991 Sec. 102(e) Date Feb. 28, 1991 PCT Filed Sep. 8, 1989 PCT Pub. No. WO90/02972 PCT Pub. Date Mar. 22, 1990.Arrangement for supporting and positioning X-ray cassettes (13) in the required position in radiography of patients confined to bed. The arrangement comprises at least one holder (10) and a lifting means (30). The holder (10) may be of different design, and in one preferred embodiment it comprises a base member (11) and a cassette support (12) extending upwardly therefrom, the base member (11) being supported by the bedstead bottom (15), and the X-ray cassette (13) being fixable standing on edge between the base member (11) and the cassette support (12). The lifting means (30) is adapted to be inserted between the bedstead bottom (15) and the mattress (14) in order to raise the latter, so that the X-ray cassette (13) is insertable in the space thus formed.
Patent FI-924779-A0 (FI)
Inventor: SCHLEYERBACH RUDOLF
IPC: C07C255/21
Filed: 1992-10-21
Abstract: The use of N-phenyl-2-cyano-3-hydroxycrotonamide derivatives of the formula I <IMAGE> where R<1> is hydrogen atom or (C1-C4)-alkyl, R<2> is CN, CX3, WCX3, W(CH2)nCX3, NO2, (CH2)nCX3, halogen, in which X is halogen, W is oxygen or sulphur atom and n is an integer from 1 to 3, R<3> is (C1-C4)-alkyl, (C3-C6)-cycloalkyl, CN or -CO-R<4> in which R<4> is (C1-C4)-alkyl or (C3-C6)-cycloalkyl, and/or the physiologically tolerated salts thereof, for the treatment of rheumatic disorders, autoimmune diseases and of rejection reactions against the transplanted organ in an organ recipient, is described.
Patent FI-941285-A0 (FI)
Inventor: LIN LEU-FEN H
IPC: C07K1/22
Filed: 1994-03-18
Abstract: A novel neurotrophic factor referred to as glial derived neurotrophic factor (GDNF) has been identified and isolated from serum free growth conditioned medium of B49 glioblastoma cells. Rat and human genes encoding GDNF have been cloned and sequenced. A gene enconding GDNF has been subcloned into a vector, and the vector has been used to transform a host cell in order to produce biologically active GDNF in a recombinant DNA process. <IMAGE>
Patent FI-951505-A0 (FI)
Inventor: KOIZUMI NAOYUKI
IPC: C07J73/00
Filed: 1995-03-29
Abstract: A 7-substituted oxa- or azasteroid compound represented by general formula (I), which has an excellent aromatase-inhibiting effect and is useful for preventing or treating diseases caused by estrogens, such as breast cancer, uterine cancer and prostatomegaly. This compound has an oxygen or nitrogen atom as the heteroatom at the position A of the ring D and the 7-position (substituent R<1>) of the skeleton is substituted by -S-R<2> (wherein R<2> represents hydrogen, lower alkyl which may be substituted by hydroxy, amino or lower alkoxycarbonyl, lower alkenyl, aralkyl, aryl which may be substituted by halogen, amino, di(lower alkyl)amino, lower alkoxy or lower alkyl, acyl, or lower alkoxycarbonyl), - S(O)m-R<3> (wherein R<3> represents lower alkyl; and m represents 1 or 2), or aralkyl.
Patent FI-954446-A0 (FI)
Inventor: NYRHILAE OLLI JUHANI
IPC: B21D26/055
Filed: 1995-09-20
Abstract: This invention relates to a method and an apparatus for forming details by means of superplastic forming the foil or plate being heated to a suitable temperature and being simultaneously exposed to a fluid pressure so that the material is slowly deformed to a predetermined shape. The heating and hence the deformation of the foil or plate takes place locally by guiding a laser beam (17) over the surface of the foil or plate (12). <IMAGE>
Patent FI-956124-A0 (FI)
Inventor: GOBLE NIGEL MARK
IPC: A61B17/32
Filed: 1995-12-19
Abstract: An electrosurgical cutting device comprises an instrument body (10), and first and second cutting blades (12,14) at least one of which is pivotally mounted on the body to execute a scissor action with respect to the other blade. Electrical supply conductors (24) associated with the body (10) supply an electrosurgical voltage to the first and second blades (12,14). The first blade (12) is a composite blade comprising a conductive outer electrode (12A), an inner conductive layer (12C) and, sandwiched between the outer electrode and the inner layer, an insulating layer (12B). The supply conductors (24) are connected respectively to the outer electrode (12A) and to the inner layer (12C). <IMAGE>
Patent AP-9901631-A0 (AP)
Title: Reverse hydroxamate derivatives as metalloprotease inhibitors.
Inventor: ANDERSEN MARC W
IPC: A61P3/10
Filed: 1998-02-24
Abstract: A family of compounds having general structural formula (i)wherein w is a reverse hydroxamic acid group (a); r5 is hydrogen or lower alkyl; r6 is (b); where z1 is heteroarylen; preferably: r1 is methyl, ethyl, isopropyl, n-propyl or 3,3,3-trifluoro-n-propyl; r2 is isobutyl or sec-butyl; r3 is hydrogen; r4 is tert-butyl, sec-butyl, 1-methoxy-1-ethyl or 2-(2-pyridylcarbonylamino)-1-ethyl; r5 is hydrogen; and r6 is 2-thiazolyl or 2-pyridyl. Such compounds show potent inhibition of mmp's, cell-free tnf convertase enzyme and tnf release from cells, and in some cases inhibit tnf convertase and tnf release from cells in preference to matrix metalloprotease.
Patent IL-62202-A0 (IL)
Title: Preparation of esters of alkanoic acids by rearrangement of alpha-haloketals
IPC: C07D317/16
Filed: 1981-02-23
Abstract: Process for preparing esters of alkanoic acids via rearrangement of alpha-haloketals in the presence of a Lewis acid.The reaction is preferably carried out in the presence of catalytic amounts of a Lewis acid and of a diluent at a temperature in the range from about 0° to the reflux temperature of the diluent.The esters thus obtained are useful as intermediate products for preparing drugs.The process involves the preparation of new alpha-haloketals.
Patent IL-69512-A0 (IL)
Title: Process for producing substituted asymmetric ureas
IPC: C07C273/16
Filed: 1983-08-17
Abstract: A process is disclosed for producing substituted asymmetric ureas, starting from dialkylcarbonates, aromatic amines and aliphatic amines, by a two-step procedure and in the presence of a catalyst selected from among the Lewis' acids and the alkoxides or the hydroxides of alkali metals or alkaline earth metals.
Patent IL-73605-A0 (IL)
Title: Preparation and purification of hyaluronic acid and sterile compositions containing it
IPC: C12P19/26
Filed: 1984-11-23
Abstract: Hyaluronic acid having controlled molecular weight and substantially free of protein and nucleic acids can be prepared from a hyaluronidase-negative or hyaluronidase inhibited microbiological source. Product may be used as replacement fluid in mammals.
Patent IL-76013-A0 (IL)
Title: Herpes virus specific immunological materials and methods
IPC: C07K1/16
Filed: 1985-08-06
Abstract: Disclosed are antibody substances displaying unique, multi-specific immunoreactivities with respect to glycoprotein D of Herpes Simplex Virus types 1 and 2 (HSV gD-1 and gD-2) and structurally related compounds. Illustratively, an IgG Type 2 monoclonal antibody material produced by mouse-mouse hybridoma cell line A.T.C.C. No. HB8606 is capable of in vitro neutralization of HSV-1 and HSV-2 infectivity and of specific immunological reactivity and reversible immunobinding with naturally-occurring and recombinant gD-1 and gD-2 in both native and denatured conformations as well as with proteinaceous materials (produced, e.g., by proteolytic digestion of naturally-occurring materials, by recombinant methods, or by polymerization of amino acids) which comprise a primary structural conformation substantially duplicating part or all of that which is predicted to be extant at residues 266 through 287 of gD-1 and gD-2 [i.e., PELA(or V)PEDPEDSAL-LEDPVtor A)GTVA(or S)]. Disclosed also are novel procedures for detection, quantification and isolation by affinity purification of gD-1, gD-2 and structurally related compounds.
Patent IL-80976-A0 (IL)
Title: 4-thienyl-dihydropyridines,their preparation and pharmaceutical compositions containing them
IPC: C07D491/048
Filed: 1986-12-15
Abstract: Blood sugar levels are reduced by administration of novel 4-thienyl-dihydropyridines of the formula   <IMAGE>   in which R1 represents 1 or 2 halogen atoms, or represents straight-chain, branched or cyclic alkyl with up to 8 carbon atoms, R2 represents a straight-chain, branched or cyclic, saturated or unsaturated hydrocarbon radical which has up to 15 carbon atoms, is optionally interrupted by one or two oxygen atoms, -N-phenyl or -SOn-(n=0, 1 or 2) and is optionally substituted by halogen, phenyl, hydroxyl, cyano, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, pyridyl, piperidino, N-phenylpiperazino, N-methylpiperazino, morpholino or N-benzyl-N-benzyl-N-methyl-amino, R3 represents hydrogen, or represents straight-chain, branched or cyclic alkyl which has up to 6 carbon atoms and is optionally substituted by halogen, hydroxyl, amino or amino-C1-C6-alkoxy, or represents cyano or formyl and R4 represents hydrogen or a straight-chain, branched or cyclic alkyl radical which has up to 10 carbon atoms, is optionally interrupted by one or two oxygen atoms in the chain and is optionally substituted by halogen, cyano, hydroxyl, phenyl, carboxyl, C1-C6-alkoxycarbonyl, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, formyl, piperidino, morpholino or thiomorpholino, or physiologically acceptable salts thereof.
Patent IL-81043-A0 (IL)
Title: Heterocyclic phenyl ethers,processes for the preparation thereof and herbicidal agents containing same
IPC: C07D213/69
Filed: 1986-12-19
Abstract: Compounds of the formula   <IMAGE> I   in which R1 denotes haloalkyl, haloalkenyl or haloalkynyl, (R2)n denotes H or up to 3 halogens, A denotes N or N->0, R3 denotes H or alkyl, and Z denotes, inter alia, a carboxyl group or a functional derivative thereof, are valuable herbicides and growth regulators.
Patent IL-83626-A0 (IL)
Title: New macrolide antibiotic,a microbiological process for its preparation,and pharmaceutical compositions containing same
IPC: C12R1/465
Filed: 1987-08-24
Abstract: The macrolide antibiotic is swalpamycin and is prepared using a Streptomyces species and is used as medicament for the treatment of infections caused by bacteria, mycoplasmas and actinomycetes.
Patent IL-85876-A0 (IL)
Title: Human manganese superoxide dismutase dna;its expression;method of recovering human manganese superoxide dismutase;human manganese superoxide dismutase analogs or human manganese superoxide dismutase mutants;uses;compositions;and methods of treatment
IPC: A61P11/00
Filed: 1988-03-25
Abstract: There are disclosed a human manganese superoxide dismutase analog in which at least one of the human manganese superoxide dismutase polypeptides differs from naturally-occurring human manganese superoxide dismutase polypeptide by the absence of lysine at the N-terminus, and a human manganese superoxide dismutase analog in which at least one of the human manganese superoxide dismutase polypeptides differs from naturally-occurring human manganese superoxide dismutase polypeptide by the absence of both lysine and histidine at the N-terminus, pharmaceutical compositions comprising same in an amount effective to alleviate the undesirable symptoms associated with the generation of oxygen free radicals and a pharmaceutically acceptable carrier, as well as their use for the production of a pharmaceutical composition for alleviating the symtoms in a subject suffering from a disorder selected from synovial inflammation, arthritis and lung fibrosis.
Patent IL-87724-A0 (IL)
Title: Ophthalmic compositions,their preparation and use
IPC: A61K9/00
Filed: 1988-09-09
Abstract: Stable, clear, antimicrobially effective, ophthalmic formulations include an ophthalmologically effective amount of a drug, especially a -COOH group-containing drug or a NSAID, and a preservative system formed of a quaternary ammonium preservative and a nonionic surfactant, all in an aqueous vehicle. These formulations are useful for treating diseases that are either caused by, associated with or accompanied by inflammatory processes, including, among others, glaucoma, cystoid macular edema, uveitis, diabetic retinopathy, and conjunctivitis, or any trauma caused by eye surgery or eye injury.
Patent AU-PP691498-A0 (AU)
Title: Improved sail craft
IPC: B63H9/06
Filed: 1998-11-02
Abstract: A sailing craft including a single hydrofoil assembly, an aerofoil assembly, and a hull assembly with a rigid beam interconnecting the hydrofoil assembly, the aerofoil assembly, and the hull assembly. The hull is separate and displaced from the hydrofoil assembly and is, in use, supported above the water by the rigid beam. The hydrofoil assembly, the aerofoil assembly, and the hull assembly are preferably interconnected such that the hydrofoil assembly and the aerofoil assembly are disposed at opposite ends of the rigid beam and the hull is connected to the beam therebetween.
Patent FI-20030169-A0 (FI)
Inventor: LINDFORS ANTTI
IPC: G01N1/02
Filed: 2003-02-04
Abstract: The invention relates to an apparatus for the continuous measurement of the quality of water in a waterway, water area or the like. The apparatus comprises a water inlet pipe fitting (2) for leading the water to be measured into the apparatus by means of a measurement line (50), at least one measuring sensor (8, 10) for making measurements of the water led into the apparatus, data management means (22, 24) for displaying and/or storing and/or processing the measured data, and a water outlet pipe fitting (14) for discharging the water passed through the measurement line (50) out of the apparatus. The apparatus is characterized in that it further comprises a bubble removal chamber (6) installed in the measurement line (50) before the measuring sensors (8, 10) for removal of air and/or gas bubbles contained by the water led into the measurement line (50). <IMAGE>
Patent IL-129616-A0 (IL)
Title: Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
IPC: C07D311/58
Filed: 1997-10-28
Abstract: The present invention relates to therapeutically active compounds of formula (I), a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
Patent IL-132669-A0 (IL)
Title: Multivalent vaccine composition with mixed carrier
IPC: A61P31/00
Filed: 1998-05-14
Abstract: The invention concerns a pharmaceutical composition for treating or preventing a certain number of infections caused by pathogenic agents such as bacteria, comprising as immunogen, one or several polyosides derived from one or several pathogenic agents. The polyosides are in the form of conjugates, coupled with a carrier protein. The composition contains at least two types of conjugates, each being at least characterised by a different protein carrier.
Patent IL-135254-A0 (IL)
Title: Magnetically shielded container
IPC: G01R33/28
Filed: 1998-09-24
Abstract: A gas storage cell containing a nuclear spin polarized gas in a gas storage space surrounded by a cell wall made of an uncoated material having a surface substantially free of paramagnetic substances which is in contact with the gas storage space and a method for removing the nuclear spin polarized gas from the gas storage cell.
Patent IL-149957-A0 (IL)
Title: Mobile phone with interactive printer
IPC: H04N19/60
Filed: 2000-11-27
Abstract: A print medium configured to be printed on by a pagewidth printhead in a print direction. The print medium includes: a laminar substrate defining first and second opposite faces; a data track containing first information encoded in accordance with a linear encoding scheme, the data track extending in a linear read direction across a portion of the first face of the print medium, the read direction being oriented at between 45 and 135 degrees with respect to the print direction; and a plurality of contiguous tags tiled across the laminar substrate. Each of the tags identifies second information and a two-dimensional coordinate position on the laminar substrate. Each of the tags is encoded in accordance with a second encoding scheme distinct from the linear encoding scheme. The information is indicative of the second information.
Patent IL-150276-A0 (IL)
Title: Indole derivatives as mcp-1 receptor antagonists
IPC: A61K31/404
Filed: 2001-01-09
Abstract: A compound of Formula I, wherein: R<SUP>1 </SUP>is hydrogen, halo, methyl, ethyl or methoxy; R<SUP>2 </SUP>is hydrogen, halo, methyl, ethyl or methoxy; R<SUP>3 </SUP>is a halo group, lower alkyl, lower alkenyl, lower alkynyl, alkoxy, trifluoromethyl, nitro, cyano, trifluoromethoxy, C(O)R<SUP>7</SUP>, or S(O)<SUB>n</SUB>R<SUP>7 </SUP>where n is 0, 1 or 2 and R<SUP>7 </SUP>is an alkyl group; R<SUP>4 </SUP>is a halo, trifluoromethyl, methylthio, methoxy, trifluoromethoxy or lower alkyl, lower alkenyl or lower alkynyl or COR<SUP>8 </SUP>where R<SUP>8 </SUP>is lower alkyl; R<SUP>6 </SUP>is hydrogen, halo, lower alkyl, lower alkenyl, lower alkynyl or COR<SUP>9 </SUP>where R<SUP>9 </SUP>is lower alkyl; provided that when R<SUP>1 </SUP>is hydrogen, halo or methoxy, R<SUP>2 </SUP>is hydrogen, halo, methyl, ethyl or methoxy, R<SUP>5 </SUP>and R<SUP>6 </SUP>are both hydrogen, and one of R<SUP>3 </SUP>or R<SUP>4 </SUP>is not halo or trifluoromethyl; or a pharmaceutically acceptable salt or prodrug thereof. These compounds have useful activity for the treatment of inflammatory disease, specifically in antagonizing an MCP-1 mediated effect in a warm-blooded animal such as a human being.