baber/WOPTO huggingface dataset:
Patent IS-6138-A (IS)
Inventor: BOYLE FRANCIS THOMAS
IPC: A61P43/00
Filed: 2001-10-30
Abstract: 1. A compound of formula (I) <CHEM> or a pharmaceutically acceptable salt thereof. wherein: n is 0-1; X and Y are independently selected from -NH-, -O-, -S-, or -NR<8>- where R<8> is alkyl of 1-6 carbon atoms and X may additionally comprise a CH2 group; R<7> is a group (CH2)mR<9> where m is 0,or an integer of from 1-3 and R<9> is a substituted aryl group, an optionally substituted cycloalkyl ring of up to 10 carbon atoms, or an optionally substituted heterocyclic ring or an N-oxide of any nitrogen containing ring; R<6> is a divalent cycloalkyl of 3 to 7 carbon atoms, which may be optionally further substituted with one or more alkyl of 1 to 6 carbon atom groups; or is a divalent pyridinyl, pyimidinyl, or phenyl ring; wherein the pyridinyl, pyrimidinyl, or phenyl ring may be optionally further substituted with one or more specified groups; R1, R2, R3 and R4 are each independently selected from hydrogen or various specified organic groups. <??>Compounds are useful as pharmaceuticals for the inhibition of MEK activity.
Patent JP-S5493545-A (JP)
Title: Cargo gear
Inventor: NISHIOKA ISHIO
IPC: B66C23/60
Filed: 1978-01-05
Abstract: PURPOSE: To improve workability, by mounting a topping bracket to a top portion of a derrick post so that the bracket be turning driven at a fixed angle, and by connecting the bracket to a nose of a derrick boom by an upper grasping rope.  
     CONSTITUTION: A projection 18 of a topping bracket 16 is fitted to an upper notch portion 19 of a derrick post 1, and turned within a limited range. When unloading a freight 20 on a quay 22, the freight 20 hung to a lifting rope 5 is lifted by means of a winch 13 under a condition that a swing rope 8 is hung to a block 14a, and the swing rope 8 is paid out. Consequently, since distance between a nose of a derrick boom 3 and an eyebolt 17 of the topping bracket 16 is constantly held by an upper grasping rope 10, the boom 3 is turned in the clockwise direction by the tension of the grasping rope 10 while being downward tilted, the paying-out of the swing rope 8 is stopped when the nose of the boom 3 is moved to a fixed location of the quay 22, and the lifting rope 5 is paid out. 
     COPYRIGHT: (C)1979,JPO&Japio
Patent JP-H10196590-A (JP)
Title: Blower in air conditioner etc.
Inventor: KIDA TAKUMI
IPC: F24F1/00
Filed: 1997-01-06
Abstract: PROBLEM TO BE SOLVED: To suppress both blowing noises from a blower and fluid noises generated from a fan guard in a blower adopted to an air conditioner or the like by suppressing large peel-off of air flow at a negative pressure surface of a vane, and also suppressing a speed increase of a discharged air flow. SOLUTION: A sectional shape of a vane 12 at its same diameter cylindrical section on the hub side 12c is rounded on the side of a front edge 12a to form a wing-like shape. A sectional area of the vane 12 at its same diameter cylindrical section on the outer peripheral side is evenly thin. It is thus possible to prevent large peel-off of air inflow from the front edge 12a, and increase of discharged air velocity from a discharge side 12b of the vane 12. It is also possible to suppress turbulance of discharged air flow when it passes a linear nember of a tan guard. It is possible to suppress both blowing noises due to peel-off on the negative pressure surface side of the vane 12 and fluid noises generated from the fan guard.
Patent CH-541146-A (CH)
Title: Sliver testing unit - with slit channel and press indicator
Inventor: ERNST FELIX
IPC: G01B13/20
Filed: 1972-01-24
Abstract: The passage of the sliver through the slit induces a compression effect between the entry and exit points, which expels air trapped between the fibres in the sliver. This air develops a press. which can be registered through a drilling in the testing unit. The volume of air displaced represents fibres density, the fluctuations in press. showing 'dead points' so that the press. indication can be converted to a correction signal for further sliver processing equipment to compensate for variations in sliver structure and quality.
Patent CR-10091-A (CR)
Title: Compuestos orgánicos
Inventor: EHARA TAKERU
IPC: A61K31/445
Filed: 2008-06-19
Abstract: La invención se refiere a compuestos de piperidina 3,5- sustituida, a estos compuestos para utilizarse en el diagnóstico y en el tratamiento terapéutico de un animal de sangre caliente, en especial para el tratamiento de una enfermedad (=trastorno) que dependa de la actividad de la renina; al uso de un compuesto de esta clase para la preparación de una formulación farmacéutica para el tratamiento de una enfermedad que dependa de la actividad de la renina.
Patent CR-10656-A (CR)
Title: Proteinas de union a interleuquina-13
Inventor: WU CHENGBIN
IPC: C07H21/00
Filed: 2009-03-06
Abstract: Proteinas de union a IL-13. Especificamente, la invencion se relaciona con anticuerpos que son quimericos, con injertos de CDR y anticuerpos humanizados. Los anticuerpos preferidos tienen gran afinidad por la hIL-13 y neutralizan la actividad de la hIIL-13 in vitro e in vivo. Un anticuerpo de la invencion puede ser un anticuerpo de longitud completa o una porcion de union al antigeno del mismo.
Patent DK-38789-A (DK)
Inventor: NIEDERMEYER UWE
IPC: C07C255/36
Filed: 1989-01-27
Abstract: The enzymatic reaction of aliphatic, aromatic or heteroaromatic aldehydes or ketones with hydrocyanic acid to give the corresponding (R)-cyanohydrins or (S)-cyanohydrins is carried out in aqueous medium in the presence of (R)-oxynitrilase (4.1.2.10) or oxynitrilase (4.1.2.11) under conditions which are sufficiently acid and at temperatures such that the chemical competing reaction and the racemisation are negligible compared with the enzymatic synthesis. The process is preferably carried out at pH values </= 4.5 and, in particular, at reaction temperatures between -5 DEG C and +50 DEG C. The reaction is preferably carried out continuously, especially in an enzyme membrane reactor. The reaction of aromatic aldehydes to give the corresponding optically active cyanohydrins is of particular interest.
Patent DK-86682-A (DK)
Inventor: KRISTENSEN NIELS
IPC: F23K/
Filed: 1982-02-26
Abstract: An apparatus for stoking of straw into a furnace has a feeding channel 3 for straw bales. Below the feeding channel 3, a back-and-forth movable cutting slide 2 for cutting off slices of straw and moving same into a straw conveying channel 1 is situated, said conveying channel being connectable with said furnace. The cutting face 2 is situated with its direction of movement crosswise to the straw conveying channel 1 and is connected to a sideways opening 8 in same. The apparatus further comprises a conveying piston 47 being movable back-and- forth in the conveying channel 1 along the sideways opening. The straw portion transferred to the straw conveying channel 1 and conveyed therein may be imparted a cross section shape being suited for combustion and being independent of the dimensions of the cutting slide. <IMAGE>
Patent DK-89590-A (DK)
Inventor: STREICHER MANFRED
IPC: F04B43/00
Filed: 1990-04-10
Abstract: A hose pump has a housing 10 with a pressure connection 14 and a suction connection 12. A first hose 22 is connected to the pressure connection and the suction connection and rests against the inner wall 24 of the housing 10. Squeezing members 26 can be moved along the hose 22 such that the hose can be squeezed by each squeezing member in the direction from the suction connection 12 towards the pressure connection 14. By virtue of the fact that this hose pump is characterized by at least one elastically deformable second hose 32, one end 44 of which ends in the interior 46 of the housing 10, and the other end 50 of which ends outside of the housing 10, and which is provided in the interior 46 of the housing in such a manner that, by moving at least two additional squeezing members 26 which can be moved on and along this hose, it can be compressed in the direction from its one end 44 to its other end 50, the negative pressure in the interior of the housing 10 necessary for the redistension of the hose is brought about. <IMAGE>
Patent GB-968171-A (GB)
Title: Improvements in or relating to polyamides
IPC: C08G69/26
Filed: 1963-01-02
Abstract: A linear polyamide is made by reacting a diamine of the formula H2N.R1.NH2 (where R1\h is a dimeric fat radical), or a mixture thereof with another diamine with either tere- or iso-phthalic acid (or a nuclear substituted derivative or an amide-forming derivative thereof) or an aliphatic or cycloaliphatic dicarboxylic acid having from 2 to 20 carbon atoms (or an amide-forming derivative thereof). The preferred method of preparation is by interfacial polymerization. The dimer diamines are derived from dimerised fatty acids. The examples disclose the preparation of polyamides from dimer diamines and: (1) terephthaloyl chloride; (2) isophthaloyl chloride; (3) hexamethylene diamine and terephthaloyl chloride; (4) piperazine and terephthaloyl chloride; (5) m-xylene diamine and tere-phthaloyl chloride; (6) ethylene diamine and tere-phthaloyl chloride; (7) hydrazine and tere-phthaloyl chloride; (8) N:N-g -amino-n-propyl decylamine and tere-phthaloyl chloride; (9) hexamethylene diamine and adipic acid; (10) to (14) hexamethylene diamine and adipoyl chloride; (15) to (21) hexamethylene diamine and sebacoyl chloride; (22), (23), (28) and (29) adipic acid; (24) sebacic acid; (25) and (27) dimethyl-1:4-cyclohexane carboxylate; (26) suberic acid; (30) and (32) 1:4-cyclohexane dicarboxylic acid and (31) diethyl oxalate.ALSO:In examples A to C solutions in toluene of polyamides derived from dimer diamine and (1) terephthaloyl chloride, (4) piperazine and terephthaloyl chloride, and (8) N : N-g -amino-n-propyl decylamine and terephthaloyl chloride are drawn on tin plate by a doctor blade, the resultant films being baked at 300 DEG F. for 30 minutes.
Patent GB-948852-A (GB)
Title: Improvements in or relating to travelling wave parametric amplifiers
IPC: H03F7/04
Filed: 1962-01-03
Abstract: 948,852. Parametric amplifiers. TELEFUNKEN PATENTVERWERTUNGS G.m.b.H. Jan. 3, 1962 [Jan. 4, 1961], No. 320/62. Heading H3B. A travelling wave parametric amplifier comprises a waveguide 1, twin conductors 2 and a number of sets of four capacitance diodes D. Each set is arranged in a plane transverse to the direction of propagation of the wave. The four diodes of a set are poled to form a ring circuit. The waveguide 1, the twin conductors 2 and the coaxial combination of the conductors 2 in the guide 1 provide three channels for the pump signal and idler waves. The twin conductors 2 may be strip conductors and the waveguide 1 may be a pair of parallel strips.
Patent GB-1020045-A (GB)
Title: Improvements in plate heat exchangers
IPC: F28F3/10
Filed: 1964-01-03
Abstract: 1,020,045. Plate - type heat exchangers. ALFA-LAVAL A.B. Jan. 3, 1964 [Jan. 11, 1963], No. 332/64. Heading F4S. A heat-exchanger comprises adjacent heatexchange plates 1, 6, 7, 8 pressed against each other to form a pack. Sealing strips 4, 5 are placed in corresponding opposed recesses which are stamped in the plates. As shown in Fig. 2, the recesses are arranged face-to-face and in front of each other so that the depth of each recess needs to be only about half the thickness of the sealing strip. Bracing projections 19, 20 &c. are stamped in the recesses and further bracing projections 21, 22 &c. are stamped in the heat-exchange surfaces 18. Said projections rest against corresponding complementary projections of neighbouring plates and afford resistance to warping. Owing to this rigidity, it is said to be possible to use wider sealing strips than hitherto, leading to an increased durability of the sealing strips and an improved sealing power. The invention relates not only to an open plate heat-exchanger, as described above and as shown, but also to closed heat exchangers where each interspace between two plates is surrounded by a sealing strip so that the pack of plates forms a series of closed chambers for the respective heat exchange media.
Patent GB-468072-A (GB)
Title: Improvements in or relating to adjusting means for brakes
IPC: F16D65/48
Filed: 1936-01-04
Abstract: 468,072. Adjusting brakes. CLENCH, E. C. S., and AUTOMOTIVE PRODUCTS CO., Ltd. Jan. 4, 1936, No. 388. [Class 103 (i)] Relates to adjustable stop devices for determining brake shoe clearance such as described in Specification 400,645 in which the stop is frictionally coupled to the backing plate, the stop being set by moving it to apply the brake and permitting it to return to an extent determined by play or lost-motion provided in the coupling means and consists in providing an arrangement whereby a number of shoes are simultaneously adjusted by a common actuating member. In Figs. 1, 2 a stop for the brake shoes 12, 13 comprises a double cam 19, the parts of which are respectively engaged by a pin 17 on shoe 12 and a projection 21 on a link 22 connected to pin 18 on shoe 13. The cam is secured to a spindle 20 which has a lost-motion connection with a sleeve 26 by means of a cross-bar 25 extending through a slot in the sleeve. The sleeve is frictionally held to the back plate 10 by a flange 29 and a washer subject to the pressure of a spring 32. To adjust the shoe clearance the spindle 20 is turned by the bar 25 until the shoes engage the drum ; if the clearance is excessive the lostmotion between the spindle and sleeve is taken up and the sleeve is turned and upon release of the bar, the shoes and the cam are returned by the release spring 14 to the extent allowed by the lost-motion. The sleeve passes through a slot in the back plate 10 to permit centring of the shoes when the adjustment is made. In a modification, the spindle 20 passes through and is frictionally coupled to a plate 26, Fig. 5, which is capable of limited rotational and lateral movement with respect to the back plate 10 permitted by bolts 40, 41 passing through slots in the plate. The clearance of the bolts in the plate determines the clearance of the shoes. In a modification of this construction, Figs. 6, 7, the spindle 20 is normally positively locked to the plate 26 by spring-pressed balls 52, 53 disposed between a part 44 on the spindle and a boss 43 on the plate. A lever 45 freely mounted on the spindle has lower and upper projections 49, which respectively engage the balls and pass through slots in a washer 46 fixed to the spindle. Movement of the lever thus disengages the balls and turns the spindle which through a friction coupling provided by a spring 48 rocks the plate 26 to the extent permitted by the bolts 39, 40. The bar 25 may be replaced by a lever connected to the spindle 20 through a free-wheel device and returned by a spring. Simultaneous adjustment of the brakes of a vehicle may be effected from a remote position by wires &c, connected to the levers,
Patent GB-950412-A (GB)
Title: Improvements relating to coated sheets
IPC: G03F7/021
Filed: 1963-01-03
Abstract: A thin layer of polyvinyl alcohol is rendered insoluble in water by heating it to a temperature of incipient dehydration to effect at least partial cross-linking.  In one example a hydrophilic coating on a base of paper or a foil of metal or plastic material comprises 100 parts by weight of titanium dioxide, 40 parts by weight of polyvinyl alcohol, 3 parts by weight of "Tergitol" (Registered Trade Mark) and 1.5 parts by weight of tributyl phosphate, together with water to make the solids content 21%.  The coating is dried and heated to above 175 DEG C. to insolubilise the polyvinyl alcohol.  At least 98% hydrolysed polyvinyl alcohol is preferably used.  A barrier coat between a paper base and the hydrophilic coating may comprise 100 parts by weight of Rhoplea, 80 parts by weight of polystyrene, 80 parts by weight of a clay slip, 2.5 parts by weight of sulphonated tallow, and 1.5 parts by weight of ammonia water, water being provided to make the solids content about 30%.  Specification 936,569 is referred to.ALSO:A hydrophilic coating on a base of paper, metal foil, or plastic material such as cellulose acetate, and suitable for imaging to form a lithographic printing plate, comprises 100 parts by weight of titanium dioxide, 40 parts by weight of polyvinyl alcohol, 3 parts by weight of "Tergitol" (Registered Trade Mark), and 1,5 parts by weight of tributyl phosphate, together with water to make the solids content 21%.  The coating is dried p  and heated to above 175  DEG C. to render the polyvinyl alcohol insoluble in water.  At least 98% hydrolyzed polyvinyl alcohol is preferably used.  In the case of a paper base it may be coated on both sides initially with cloy bound by starch or casein.  A barrier coat comprising 160 parts by weight of Rhoplex, 80 parts by weight polystyrene, 80 parts by weight of a cloy slip, 2,5 parts by weight of sulphonated tallow, and 1,5 parts by weight of ammonia water, water being provided to make the solids content about 30%.  Specification 936,569 is referred to.
Patent GB-1402201-A (GB)
Title: Forging presses
IPC: B21J9/18
Filed: 1973-01-03
Abstract: 1402201 Forging presses KOMBINAT UMFORMTECHNIK ERFURT VEB 3 Jan 1973 403/73 Heading B3H  An eccentric operated forging press has its slide 2 driven by a double legged connecting rod 11 joined to an eccentric bushing 3 in the slide, which bushing is used to effect adjustment of the tool position relative to the bottom tool without changing the slide stroke. The bushing is mounted on a bolt (12), Fig. 2 (not shown), through the legs of the connecting rod 11 and held in a transverse recess in the slide 2 by a yoke 4. The yoke is biased against the bushing by double-arm levers 5 of which the outer ends are pivoted to pistons 13 of slide balancing cylinders 6. The eccentric bushing is rotated by a worm shaft 9 in engagement with a wormwheel segment 8. The adjustment is effected when the yoke is released from its tight engagement with the bushing by the unloading of the balancing cylinders 6.
Patent GB-346663-A (GB)
IPC: G07F13/02
Filed: 1930-01-06
Abstract: 346,663. Coin-freed liquid-dispensing apparatus. KONIECZNY, J., 18, Derfflingerstrasse, and KAPPIS, L., 10, Schoneberger Ufer, both in Berlin. Jan. 6, 1930, No. 474. Convention date, Jan. 7, 1929. [Class 27.] Time-controlled apparatus; coin action, weight.-An electrically-operated c o i n - freed device for delivering petrol comprises an electric pump 12 the circuit of which is closed, after the insertion of a coin, for a period determined by clockwork during which petrol is pumped from a storage tank through pipes 23, 24 to a container 25 provided with a delivery pipe 26, tap 27 and hose 28. A coin, inserted through a shoot 1, tilts a spring-actuated plate 2 carrying a contact arm 6. The contacts 6, 19 are closed to energize an electromagnet 10 which attracts a pivoted lever 14, 15 thereby breaking contacts 16, 17 in the electromagnet circuit and closing contacts 13, 21 in the electric pump circuit. The lever 14, 15 through a contact lever also winds up a clockwork, which, as it runs down, returns a lever to its starting position, this lever restoring the lever 14, 15 to its initial position to stop the pump. The coin after tilting the plate 2 drops to a container 4.
Patent GB-346772-A (GB)
Title: Improvements in machines for filling and weighing bags and the like
IPC: B65B1/18
Filed: 1930-01-07
Abstract: 346,772. Automatic-feed weighers. SOC. D'ETUDES D'ENSACHAGE ET DE MANUTENTION, 24, Rue Bugeaud, Lyons, France. Jan. 7, 1930, No. 639. Convention date, Jan. 7, 1929. [Class 143.] A machine for filling and weighing bags, particularly those of the valve type, comprises, a hopper a with agitators b, c, d, forwarding the material to the outlet e. A bag f is placed on the outlet e and is held by a support 2 on a weigh-beam 3 balanced by a weight 4. The beam is pivoted at 5 and carries a cam 6 upon which a roller 8 on an arm 9 is caused to run by a 'counterweight 7. When the bag is in position a pedal g is depressed and lowers a rod h, rotating' a plate j about its axis k so that an opening l therein registers with the outlet e. The plate is temporarily held in this position by the engagement of catches x, w. The movement of a rod also opens a valve p and engages the drive with the agitating means. As soon as the weight of material in the bag rocks the beam the cam 6 is moved so as to allow the arm 9 and shaft 20 to rock. This causes a roller 11 to strike a lever 13 and withdraw the catch x so that the outlet e, and the valve p, are closed; and the drive is disconnected.
Patent GB-929435-A (GB)
Title: Improvements in or relating to polypropylene
IPC: C08K5/13
Filed: 1960-01-07
Abstract: Polypropylene is stabilized with a composition comprising (a) a hundred phenol selected from 2, 4, 6 - trialkyl phenols, and phenols of the formula, <FORM:0929435/IV(a)/1> where B is a radical selected from the group consisting of <FORM:0929435/IV(a)/2> and <FORM:0929435/IV(a)/3> wherein n is 0 to 8, one A on each ring is a hydroxyl group and the other is R1, X is selected from R and hydroxyl, R is a 1-16 hydrocarbon radical, and R1 is R or hydrogen, and (b) a thio compound selected from (1) metal dialkyl dithiocarbamates of the general formula <FORM:0929435/IV(a)/4> where M is a Group IIa metal and R1 and R2 are hydrocarbon radicals of 1 to 6 carbon atoms, (2) trialkyl trithiophosphites, (3) thioethers of carboxylic acid esters of the formula, <FORM:0929435/IV(a)/5> where r is a hydrocarbon radical, and n is an integer from 1 to 6, and (4) thioethers of the formula R-S-R, where R is a hydrocarbon radical. Components (a) and (b) are each present in the composition in an amount of 0,005 to 2 parts by weight.  The composition may also include an epoxy resin such as one made by the condensation of a bisphenol and epichlorohydrin. TThe Specification mentions a large number of suitable ingredients for the composition.  Compositions exemplified are (1) two ingredient systems consisting of 2,21-methylene-bis-(4-ethyl-6-t-butyl phenol) and zinc dibutyl dithiocarbamate, or dilauryl thiodipropionate, or dihexadecyl sulphide, 4,41\-methylene-bis-(2,6-di-t-butyl-phenol and dilauryl thiodipropionate, bis(2-hydroxy-3-t-butyl-5-methylphenylmethyl) durene and dilauryl thiodipropionate, or trilauryl trithiophosphite, 2-6-bis(2-hydroxy-3-t-butyl-5-methyl benzyl) 4,methyl phenol, and dilauryl thiodipropionate, 2,6-and zinc dibutyl di-thiocarbamate, or dilauryl thiodipropionate, or trilauryl trithiophosphite, or dihexadecyl sulphide, (2) three ingredient systems consisting of 2,21-methylene-bis(4-ethyl-6-t-butyl phenol) zinc dibutyl thiocarbamate, and calcium stearate or barium-cadmium laurate, 2,6-di-t-butyl-p-cresol, calcium stearate and dilauryl thiodipropionate or zinc dibutyl dithio carbamate, 4,41-methylene-bis(2,6-di-t-butyl phenol, dilauryl thiodipropionate, and calcium stearate or barium-cadmium laurate, 2,6-bis(2-hydroxy-3-t-butyl-5-methyl benzyl)-4-methyl phenol, trilauryl trithio phosphite, and butyl epoxy stearate, bis(2-hydroxy-3-t-butyl-5-methyl phenyl methyl) durene, dilauryl thiodipropionate, and calcium stearate, and (3) four ingredient systems consisting of 2,21-methylene-bis-(4-ethyl-6-t-butyl phenol) or 4,41-methylene-bis(2,6-di-t-butyl phenol, calcium stearate, an epoxy resin, and dilauryl thiodi-propionate or dihexadecyl sulphide, and 2,6-di-t-butyl-p-cresol, dihexadecyl sulphide, calcium stearate, and an epoxy resin.  Polypropylene stabilized with the above compositions is stated to be resistant to heat degradation for periods in excess of 400 hours at 280 DEG F.