baber/WOPTO huggingface dataset:
Patent SK-7232003-A3 (SK)
Title: Benzodiazepine derivatives as GABA A receptor modulators
Inventor: MASCIADRI RAFFAELLO
IPC: A61P43/00
Filed: 2001-11-08
Abstract: The present invention relates to compounds of formula (I), wherein R<1> is hydrogen, halogen, lower alkyl, lower alkoxy, hydroxy, cyano, trifluoromethyl, trifluoromethoxy or lower alkylthio; R<2> is -C(O)O-lower alkyl, isoxazol, 1,2,4-oxadiazol-3-yl or 1,2,4-oxadiazol-5-yl, which rings may be substituted by lower alkyl, trifluoromethyl or cycloalkyl; R<3> is hydrogen, lower alkyl, -(CH2)n-cycloalkyl, -(CH2)n-halogen, -(CH2)n-pyridin-4-yl, or -(CH2)n-phenyl, wherein the phenyl ring may be substituted by one or two substituents selected from the group consisting of lower alkoxy, halogen, -SO2CH3, phenyl, OCF3, nitro, CF3, -NR2, or is -(CH2)n-indolyl, optionally substituted by lower alkyl or lower alkoxy, or is pyrrolidinyl-5-oxo, -C(O)-NR2, -(CH2)n-OH, -(CH2)n-NR2 or -(CH2)n-benzo[1,3]dioxole; R is hydrogen or lower alkyl; and n is 0, 1, 2 or 3; and to their pharmaceutically acceptable acid addition salts. These compounds have a good affinity to the GABA A  alpha 5 receptor and they are therefore useful for the treatment of diseases, related to this receptor.
Patent SK-8072001-A3 (SK)
Title: The method of waste water treatment and the aero-selector for the realisation of this method
Inventor: KURILEC JAN
IPC: C02F3/12
Filed: 2001-06-11
Abstract: The waste water treatment is realised in such a way that the waste water after the optional removal of coarse materials and/or the waste water from the adjoined anaerobic area (17) is recycled in the activation tank (1) through the oxic and anoxic part of the activation by the means of escaping air bubbles created after the air loading into the aeration device (8). At the same time sediments are washed away from the sedimentation tank (2). By the means of the optional creation of the water jump (10) onto the slot (7) by the appropriate velocity of the recycled water and air escaping from the aeration device (8) the activation mixture is pumped into the sludge area or the anaerobic area in the case of phosphorus removal. The cleaned waste water is discharged via the collection channel (11) into recipient. The aero-selector for waste water treatment consists of cylindrical, horizontal activation tank (1) on which the sedimentation tank (2) is connected whose bottom part opens radially into the lower part of the activation tank (1) and this opening area is adapted for the sedimentation degassing. The activation tank (1) is inside equipped with the aeration device (8) for the recycling and aeration of the activation mixture and with an upper opening (5) created along the activation tank (1) in the highest point of its wall. The slot (7) created between the inner wall of the activation tank (1) and the plate-shaped part (6) can end in the opening (5). The activation tank (1) can be equipped with a sludge carrier (9) of cylindrical shape with at least one opening.
Patent SU-422134-A3 (SU)
IPC: C07C35/20
Filed: 1971-11-10
Granted: 1974-03-30
Abstract: 1344653 Alcohols and esters L GIVAUDAN & CIE SA 10 Nov 1971 [10 Nov 1970] 52176/71 Heading C2C [Also in Division A5] The invention comprises compounds of the formula where R<SP>1</SP> is H or methyl, R<SP>11</SP> is H or alkanoyl of 1-3 carbon atoms, R<SP>111</SP> is butyl, Z is -C#C-, -CH=CH- or -CH 2 -CH 2 - and n is 0-2. The compounds are prepared by .reacting together compounds of the formula and MZR<SP>1</SP> where M is an alkali metal or MgX where X is halogen, provided that M is an alkali metal only when Z is -C#C-, and alkanoylating or hydrogenating the product if desired.
Patent SU-1109074-A3 (SU)
Title: Формирователь адресных токов дл блоков пам ти
Inventor: KSIONZHEK YANUSH
IPC: H03K17/04
Filed: 1975-09-25
Granted: 1984-08-15
Abstract: ФОРМИРОВАТЕЛЬ АДРЕСНЫХ ТОКОВ  ДЛЯ БЛОКОВ ПАМЯТИ, содержащий  входной трансформатор, один конец  первичной обмотки которого подключен  ко входу формировател , другой  через  резистор к одному источнику питани , первый конец вторичной обмотки  входного трансформатора через разв зывающий  диод подключен к базе ключевого  транзистора и к одному концу  согласующего резистора, второй конец  вторичной обмотки входного трансформатора  соединен с эмиттером ключевого  транзистора и другим концом согласующего  резистора, коллектор ключевого  транзистора соединен с другим источником  питани , отличающийс    тем, что, с целью повышени   быстродействи  формировател , он содержит  управл ющий транзистор, а  входной трансформатор - дополнительi  ную вторичную обмотку, один конец  которой соединен с базой управл ющеСО  го транзистора, а другой - с его  эмиттером и одним концом вторичной  обмотки входного трансформатора, коллектор  управл ющего транзистора подключен  к базе ключевого транзистора. о  4:
Patent SU-786853-A3 (SU)
Inventor: NAGATSU TOSIKHARU
IPC: C12Q1/37
Filed: 1976-10-29
Granted: 1980-12-07
Abstract: 1518207 Determination of a prolyldipeptidylaminopeptidase AJINOMOTO Co. Inc. 29 Oct 1976 [30 Oct 1975 ] 45200/76 Heading G1B [Also in Divisions C2 and C3] A diagnostic reagent comprises a compound of Formula wherein X is an amino acid radical, YNH is the residue of YNH 2  wherein YNH 2  is selected from p-nitroaniline, p-phenylazoaniline, 4-phenylazo-1- naphthylamine; or an acid salt thereof, which compound may be porous. X is preferably the radical of an amino acid of up to 15 carbon atoms, most preferably selected from glycine, L-alanine, L-glutamic acid, L-aspartic acid, L-lysine and L-arginine, and the acid in the acid salt is preferably p-taluenesulphonic acid, hydrochloric acid or hydrobromic acid. A method of measurement of the activity of X-prolyldipeptidylaminopeptidase comprises contacting a compound of Formula X-Pro-NHY or an acid salt thereof with said X-prolyldipeptidylaminopeptidase in an aqueous medium at a pH of 6 to 9, preferably at 30‹C to 45‹C, and assaying the liberated YNH 2 . The process may be adapted to detect disease in a mammal (including homosapiens) by measurement of the YNH 2  liberated obtained by contacting serum which contains X-prolyldipeptidylaminopeptidase with a compound of Formula X-Pro-NHY, or an acid salt thereof, in an aqueous medium at 30‹C to 45‹C and at pH of 7À5 to 8À9. In the Examples, human serum and/or purified human submaxillary enzyme is assayed with glycylh-proline p-nitroanilide, L-hysyl-L-proline p-nitroanilide, L-alanyl-L-proline p-nitroaniline, L-glutamyl-L-proline p-nitroanilide, L-aspartyl-L- proline p-nitroanilide, glycyl-L-proline p-phenylazoanilide tosylate, glycyl-L-proline -nitroamilide tosylate. The liberated p-nitroaniline and p-phenylazoaniline are assayed spectrophatometrically.
Patent SU-710520-A3 (SU)
Inventor: GOLZER LEOPOLD
IPC: C08J9/02
Filed: 1977-07-29
Granted: 1980-01-15
Abstract: An aqueous solution of water-soluble amino resin precondensates is condensed with organic isocyanates, firstly amines and/or organometallic compounds being added to the organic isocyanate, and simultaneously, but separately from one another, a solution of the amino resin precondensate and acidic curing catalysts then being added to the mixture. Foaming inevitably occurs during this operation. The process enables the preparation of, in particular, lightweight foams without the use of particular foaming (blowing) agents. Three different catalyst groups act in concert, with no mutual inhibition. An appropriate choice of the amino resin component, the water content, the amount of polyisocyanate and the combination of the acidic, basic or organometallic catalysts makes it possible to produce, in an economical manner and in a single step and a short production time, foams having good fire and insulation properties which cure tack-free without further thermal aftertreatment.
Patent SU-1138029-A3 (SU)
Title: Способ получени 5-замещенных 1,2-дигидро-3 @ -пирроло- @ 1,2 @ -пиррол-1-карбоновых кислот
Inventor: KHORN ALBERT R VAN
IPC: C07D487/04
Filed: 1978-07-24
Granted: 1985-01-30
Abstract: СПОСОБ ПОЛУЧЕНИЯ 5-ЗАМЕЩЕННЫХ  1,2-ДИГИДРО-ЗН-ПИРРОЛО-
Patent SU-1166669-A3 (SU)
Inventor: DZHONSON OLIVER VENDELL
IPC: F15B11/00
Filed: 1979-02-05
Granted: 1985-07-07
Abstract: A fluid controller is disclosed of the type including a primary valve member, and a follow-up valve member. The controller includes a load signal port and a load signal chamber. Fluid is communicated from the inlet port to the load signal chamber, and the valve members define a neutral orifice communicating between the load signal chamber and the return port when the valving is in neutral. The valving defines operating orifices communicating fluid from the load signal chamber to the main fluid path, downstream of the main flow control orifice, when the valving is shifted away from neutral. The operating orifices have a smaller orifice area when the valving approaches maximum deflection. The result is a substantially higher differential operating pressure, and a higher flow rate than would otherwise be possible at that particular valve deflection.
Patent SU-984410-A3 (SU)
Inventor: VIDRA ILDIKO
IPC: C07C309/73
Filed: 1979-05-11
Granted: 1982-12-23
Abstract: Xylitol derivatives of the general formula   <IMAGE> wherein R<1> and R<5> are the same and represent halogen, tosyloxy or mesyloxy, in which case  R<2> and R<4> represent hydroxy or  R<1> and R<2> as well as R<4> and R<5> together form oxygen bridges,  R<3>, whatever the values of R<1>, R<2>, R<4> and R<5>, is hydrogen, alkanoyl, aralkanoyl or aroyl, exhibit cytostatic activity. They can be prepared from xylitol by standard methods. The compounds can be formulated for pharmaceutical use in conventional manner.
Patent SU-1609444-A3 (SU)
Inventor: YAMAGUTI YASUMASA
IPC: C12R1/365
Filed: 1980-05-05
Granted: 1990-11-23
Abstract: A process for the continuous production of acrylamide or methacrylamide from acrylonitrile or methacrylonitrile by use of a microorganism capable of promoting the hydration of acrylonitrile or methacrylonitrile into the corresponding amide. Said process comprising immobilizing the microorganism or enzyme extracted therefrom, continuously bringing the acrylonitrile or methacrylonitrile into contact with the immobilized microorganism or enzyme in at least one reactor containing an aqueous medium at a pH pf 6 to 10 to cause the hydration reaction, and recycling a part of the reacted solution to dilute the unreacted acrylonitrile or methacrylonitrile and water therewith.
Patent SU-1347866-A3 (SU)
Inventor: BERNARD GEORG AUGUSTINUS PAULI
IPC: A23J7/00
Filed: 1984-03-16
Granted: 1987-10-23
Abstract: The present process for removing impurities from a triglyceride oil includes admixing a hydrolyzed phosphatide and water with the oil, separating the oil into an oil portion and a sludge portion and separating the sludge portion into an aqueous phase and an oil phase. The presence of the hydrolyzed phosphatides can aid the two separation steps. Recovery of oil from the sludge is thus possible.
Patent SU-1582971-A3 (SU)
Inventor: MANSER JOSEF
IPC: A23L7/109
Filed: 1986-08-22
Granted: 1990-07-30
Abstract: A process for the production of dough products whereby the soft products which emerge from a pressing head are fed through differentially-heated climatic zones until dry, and are cooled and/or stabilized in respect of their shape on completion of the drying process. The dough products are heated in an initial climatic zone to a temperature of 80 to 100<o>C accompanied by at least slight drying, and then exposed for about 30 seconds to 20 minutes to freshly-depressurized superheated steam. Finally, the dough product is dried in a controlled drying climate. Furthermore, a description is given of the dough products which can be thus obtained and a particularly well-suited device for the implementation of this process. The device comprises a drier, steam oven, a second drier and means for controlling the climatic conditions.
Patent SU-1637665-A3 (SU)
Inventor: LAMERAN ZHAN-MISHEL
IPC: C01F7/47
Filed: 1987-10-22
Granted: 1991-03-23
Abstract: 1. A method of recovering the gallium contained in an aqueous solution of highly alkaline sodium aluminate by exchange of chemical species between a stationary phase consisting of a microporous adsorbent resin impregnated with a 7-alkenyl 8-hydroxy quinoline charge and the aqueous phase of sodium aluminate characterised by the fact that prior to impregnation the dry resin has a specific surface area, measured by the BET method, which is at least equal to 450 sq.m/g of resin, a pore volume at least equal to 1500 cu.mm/g of resin, a mean pore diameter of between 8.0 and 50.0 nm with at least 80% of this volume consisting of pores of a diameter comprised between 4.0 and 500.0 nm, an expansion rate in an aqueous medium not exceeding 20%, and in that it is impregnated with 7-alkyl or alkenyl 8-hydroxy in a proportion of 250 to 350 g per litre of dry resin.
Patent SU-1715205-A3 (SU)
Inventor: NIK FRANSUA
IPC: A61K31/585
Filed: 1987-11-24
Granted: 1992-02-23
Abstract: Products having the formula (I) wherein R1 is an aryl or aralkyl, R2 is a hydrocarbonated radical (1-18 carbon atoms), the dotted lines indicate an optional bond, the cycles A, B and C represent (II), (III), (IV), (V), (VI); R' and R'' are H, alkyl (1-4 carbon atoms), Re is H, alkyl (1-6 carbon atoms), acyl, and their salts, their preparation, their application as medicaments, the pharmaceutical compositions containing them and intermediaries.
Patent SU-1813309-A3 (SU)
Title: Electrode unit of plasma generator to heat water steam
Inventor: LUKASHOV V P
IPC: H05B7/22
Filed: 1991-01-14
Granted: 1995-03-27
Abstract: FIELD: plasma equipment. SUBSTANCE: electrode unit has hollow cylindrical electrode with ring cooling space in its wall and two cylindrical parts coupled to branch pipes of inlet and outlet of water steam. Relation of length and butt part of electrode is chosen equal to 1.3-1.5. EFFECT: simplified design, enhanced operational efficiency. 1 dwg
Patent WO-0042544-A3 (WO)
Title: Extraction d'informations de sites web concernant des vendeurs
Inventor: JOHNSON ERIC W W
IPC: G06Q30/00
Filed: 2000-01-18
Abstract: L'invention concerne une base de données ainsi que des procédés et des outils de création, d'entretien et de mise à jour de la base de données pour stocker des informations concernant des vendeurs, ces informations étant utiles dans des marchés facilités par des technologies. Les informations concernant les vendeurs, stockées dans la base de données, permettent de compiler automatiquement des listes de vendeurs qui présentent une proximité géographique arbitraire par rapport à un client, d'offrir un produit ou un service voulu par le client, et de répondre à diverses préférences de client. Les outils de création et de mise à jour de la base de données permettent d'extraire des informations provenant de diverses sources d'information, tels des sites Web d'Internet, d'améliorer et de mettre à jour la base de données en continu.
Patent WO-0115618-A3 (WO)
Title: Pontage vasculaire non occlusif et instruments a cet effet
Inventor: HSU THOMAS H S
IPC: A61F2/06
Filed: 2000-08-31
Abstract: La présente invention concerne des moyens de pontage vasculaire non occlusif pouvant être mis en oeuvre en chirurgie ouverte ou en laparoscopie. L'invention concerne plus particulièrement un procédé de pontage vasculaire consistant en l'implantation d'une endoprothèse chez le patient, sans occlure le vaisseau du patient, ou l'un au moins du vaisseau sanguin donneur ou récepteur selon l'intervention. On fixe aux endroits voulus par ses deux extrémités le nouveau segment, puis on découpe une ou deux pièces dans la paroi vasculaire, mais on les retient par des dispositifs de prise de paroi vasculaire faisant également partie de l'invention. La section se fait au moyen d'un laser excimère, d'un scalpel circulaire, d'un perforateur aortique ou de tout autre dispositif convenant. Il ne reste plus qu'à enlever les pièces au moyen des dispositifs de prise.
Patent WO-0107965-A3 (WO)
Title: Systeme de mesure de la lumiere en avant du film pour cameras electroniques
Inventor: WHALEN MATTHEW S
IPC: G03B7/099
Filed: 2000-07-26
Abstract: Cette invention concerne un système imageur électronique prévu pour recevoir une pellicule photographique, qui coopère avec un système de mesure de la lumière en avant du film (OTF). Le système imageur comprend une combinaison de couches anti-réflexion, de couches à réflectance diffuse et de couches d'absorption de la lumière qui règlent la réflexion du système imageur et donc limitent une réfelxion qui provoquerait une fausse lecture de la part du système imageur. Les couches sont appliqués sur l'ensemble détecteur d'image et autres composants dotés de propriétés réfléchissantes élevées. L'agencement géométrique et les combinaisons des traitements qui modifient la réflexion peuvent être adaptés à la géométrie particulière du système de mesure en avant du film au même titre que la disposition du détecteur et des composants électroniques dans le système imageur électronique.
Patent WO-0140476-A3 (WO)
Inventor: BULLA LEE A JR
IPC: A01N63/50
Filed: 2000-10-25
Abstract: A composition and method for killing fire ants is disclosed that includes the purified and activated Cry toxin from a novel strain of Bacillus thuringiensis, wherein the water soluble, partially purified, activated toxin is provided along with an attractant to kill the imported fire and using a biodegradable, environmentally sound glycoprotein without a need for toxic chemicals.
Patent WO-0166310-A3 (WO)
Title: Outil utile pour enlever des vis abimees
Inventor: BERGAMO PETER J
IPC: B25B23/00
Filed: 2001-02-23
Abstract: L'outil selon la présente invention est installé dans un foret tournant en sens horaire inverse. L'outil comprend un axe et une extrémité pointue ayant une pointe de 140° environ. L'outil comporte plusieurs surfaces de raclage qui se font face dans le sens horaire inverse à l'intérieur d'un évidement longitudinal formé dans l'extrémité pointue. Chaque surface de raclage comporte un bord de raclage formé à un angle de 70° environ par rapport à l'axe. Derrière les surfaces de raclage, la surface extérieure de l'extrémité pointue s'incurve vers le bas dans une surface en dépouille en direction d'un bord orienté vers l'arrière situé à proximité immédiate d'un autre évidement longitudinal.
Patent WO-0162198-A3 (WO)
Title: Air fluidized bladders for a bed
Inventor: SOLTANI SOHRAB
IPC: A47C20/04
Filed: 2001-02-23
Abstract: A preferred embodiment mattress (1010) for a bed is provided to support a patient. The mattress (1010) includes a plurality of air fluidized bladders (1022). Each bladder (1022) includes a fluidized zone (1028) having fluidizable material positioned therein. Each bladder (1028) further includes at least one diffuser (1036, 1038) configured to provide air to the fluidized zone (1028) to fluidize the material.
Patent WO-0168017-A3 (WO)
Title: Ameliorations apportees au stockage et a la distribution de produits pharmaceutiques multi-dose sans agents de conservation
Inventor: BOYLES JAMES V C
IPC: A61F9/00
Filed: 2001-03-09
Abstract: L'invention concerne un appareil de distribution de produits pharmaceutiques multi-dose sans agents de conservation, comprenant un contenant flexible composé d'un stratifié sous forme de film, destiné à contenir et à conserver une formulation médicamenteuse stérile. Un embout situé à l'intérieur du contenant et en communication fluidique avec ce dernier permet d'obtenir une distribution au goutte-à-goutte de la formulation depuis le contenant flexible. Cet embout comprend une interface composée de parties internes et externes de l'embout qui est normalement scellé. La partie externe de l'embout est suffisamment flexible pour permettre son allongement et le passage de la formulation sèche à l'aide d'un piston destiné à extraire des volumes sélectionnés de la formulation du contenant.
Patent WO-0168861-A3 (WO)
Inventor: JARDETZKY THEODORE S
IPC: C12N15/13
Filed: 2001-03-15
Abstract: The present invention includes three-dimensional models of antibodies, such as Fc-Cε3/Cε4 regions of IgE antibodies, as well as methods to produce such models. The present invention also includes muteins having increased stabiltiy and/or antibody receptor binding activity, as well as methods to produce such muteins, preferably using information derived from three-dimensional models of the present invention. Also included are nucleic acid sequences encoding muteins of the present invention and use of those sequences to produce such muteins. Also included is the use of themodel to identify compounds that inhibit the binding of an antibody receptor protein to an antibody. The present invention also includes uses of such muteins and inhibitory compounds, for example, in methods to diagnose and protect animals from allergy and othter abnormal immune responses.
Patent WO-0175077-A3 (WO)
Inventor: FALLON ROBERT D
IPC: C12P13/00
Filed: 2001-03-30
Abstract: Cette invention concerne des souches microbiennes recombinantes qui expriment une enzyme nitrilase et qui conviennent bien comme biocatalyseurs pour l'hydrolyse de substrats renfermant des nitriles. Les cellules recombinantes sont transformées au moyen d'un gène étranger isolé de Acidovorax facilis 72W codant pour une enzyme nitrilase thermostable qui, en conditions de réaction douces, catalyse l'hydrolyse, en acides carboxyliques, de substrats renfermant des nitriles. L'invention porte sur la séquence nucléotidique du gène de nitrilase et la séquence d'acides aminés qui en est résulte et qui est codée par ledit gène.
Patent WO-0189767-A3 (WO)
Inventor: VANELL JAMES F
IPC: B24B37/04
Filed: 2001-04-06
Abstract: A method of manufacturing a semiconductor component includes forming a first layer over a semiconductor substrate, providing a mixture comprised of a first component and a second component, optically detecting a concentration of the first component in the mixture, and applying the mixture to the first layer. A chemical-mechanical polishing (CMP) system (100) for use in the method includes a vessel (110) having a first input port (111), a CMP slurry output port (113), and a CMP slurry sensing port (114). The CMP system also includes a refractometer (150) adjacent to the CMP slurry sensing port.
Patent WO-0187993-A3 (WO)
Title: Composes alkoxy polymeres accouples a une chaine, a viscosite modulee
Inventor: HOGAN TERRENCE E
IPC: C08F8/42
Filed: 2001-05-10
Abstract: Cette invention concerne des composés alkoxy polymères accouplés à une chaîne s'utilisant comme composante élastomère dans des compositions élastomères vulcanisables concernant de la silice, du noir de fumée, ou un mélange de ces deux substances. L'invention porte en particulier sur des polymères à polymérisation anionique dont les extrémités vivantes de chaîne polymère sont fonctionnalisées avec des groupes alkoxy et qui sont reliés les uns aux autres par un atome de métal ou de non métal. Les composés alkoxy polymères présentent une viscosité initiale élevée qui facilite leur manipulation avant compoundage, une viscosité stable pendant le stockage et une viscosité réduite garantissant une meilleure dispersion de la charge et plus grande efficacité au mélange. Cette invention concerne également un pneumatique dont une composante au moins est produite à partir de la compositions élastomère vulcanisable selon l'invention.
Patent WO-0204352-A3 (WO)
Title: Synthese mecanochimique de dioxyde de manganese lithifie
Inventor: CHRISTIAN PAUL A
IPC: H01M6/16
Filed: 2001-07-05
Abstract: L'invention porte sur un procédé amélioré de préparation de dioxyde de manganèse lithifié présentant une structure cristalline stabilisée de type η-MnO2 consistant à soumettre un mélange essentiellement sec de dioxyde de manganèse et d'un sel de lithium à un traitement mécanique en présence d'un milieu de mélange. Le procédé mécanique d'activation favorise l'échange partiel des ions protons présents dans le réseau cristallin du dioxyde de manganèse et à la surface des particules dudit dioxyde, par des cations de lithium. Le produit intermédiaire ainsi formé est chauffé pour obtenir dioxyde de manganèse lithifié de structure cristalline de type η-MnO2 facilement incorporable à la cathode d'une cellule électrochimique primaire au lithium.