baber/WOPTO huggingface dataset:
Patent WO-2021163531-A1 (WO)
Title: Neuromodulation therapy with a multiple stimulation engine system
Inventor: DESHAZO DARAN
IPC: A61N1/04
Filed: 2021-02-12
Abstract: An implantable medical device (IMD) (102, 150) includes multiple stimulation engines (SEs) (402-i) for independently stimulating respective electrode sets of a lead system (106A/B, 186). A voltage multiplier (VM) (302) is configured to generate an adjustable target voltage at an output node (304). Each stimulation engine (402-i) includes first switching circuitry (452) to switchably connect an anodic node (456) of the SE (402-i) to a VM connection node (450) driven by the output node (304) and second switching circuitry (434) to switchably connect a cathodic node (458) of the SE (402-i) to a current sink circuit (422). Discharge switching circuitry (472) may be disposed between the anodic and cathodic nodes (456, 458) of each SE (402-i). A selector (408) and associated digital control logic block (404) are operative to generate control signals (405A, 405B) for independently controlling respective SEs (402-i) such that each SE may be activated to stimulate or discharge a corresponding select set of electrodes (412) independently from or in concert with remaining SEs.
Patent WO-2021178301-A1 (WO)
Inventor: NOWAK BRIAN J
IPC: B01D3/22
Filed: 2021-03-01
Abstract: Trays having increased capacity and efficiency are described. The trays have a deck, and downcomers extending through the deck. There are a plurality of bubble promoters on the deck. Each bubble promoter defines a zone on the deck, and the zone has an opening in the deck. The opening is positioned adjacent to a solid support for the tray. The bubble promoters provide areas through which vapor can passing, turning blocked areas of the tray into active areas. Mass transfer columns containing the trays are also described.
Patent WO-2021183586-A1 (WO)
Title: Handle for a personal care system
Inventor: SIEGMANN ERIC
IPC: B26B21/44
Filed: 2021-03-10
Abstract: A handle for a personal care system with a first end having a head configured to engage a shaving cartridge, a second end with a partially enclosed ring having a first arm with a first end facing a first end of a second arm to defines a gap having a width. The first and second arms define an undercut region below the gap. A lower surface extends between the partially enclosed ring and the head, wherein the lower surface and the partially enclosed ring are configured to receive a container.
Patent WO-2021202552-A1 (WO)
Title: Improved techniques for out-of-domain (ood) detection
Inventor: DUONG Thanh Long
IPC: G06F40/35
Filed: 2021-03-30
Abstract: The present disclosure relates to techniques for identifying out-of-domain utterances. One particular technique includes receiving an utterance and a target domain of a chatbot, generating a sentence embedding for the utterance, obtaining an embedding representation for each cluster of in-domain utterances associated with the target domain, predicting, using a metric learning model, a first probability that the utterance belongs to the target domain based on a similarity or difference between the sentence embedding and each embedding representation for each cluster, predicting, using an outlier detection model, a second probability that the utterance belongs to the target domain based on a determined distance or density deviation between the sentence embedding and embedding representations for neighboring clusters, evaluating the first probability and the second probability to determine a final probability, and classifying the utterance as in-domain or out-of-domain for the chatbot based on the final probability.
Patent WO-2021202874-A1 (WO)
Title: Furin inhibitors for treating coronavirus infections
Inventor: WILCOXEN KEITH
IPC: A61K31/165
Filed: 2021-04-01
Abstract: Provided herein are methods, pharmaceutical compositions, and kits for treating and/or preventing a viral infection resulting from a coronaviridae family virus in a subject in need thereof, comprising administering to the subject a compound of Formula (I), or a pharmaceutical composition comprising a compound of Formula (I). Further provided herein are methods for inhibiting the viral entry into a cell of a coronaviridae family virus (e.g., alphacoronavirus (e.g., HCoV-NL63, HCoV-229E), betacoronavirus (e.g., SARS-CoV, SARS-CoV-2, MERS-CoV, HCoV-OC43, HCoV-HKUl)) in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising a compound of Formula (I) as described herein. Also provided are pharmaceutical compositions and kits comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for use in the treatment and/or prevention of a viral infection resulting from a coronaviridae family virus in a subject in need thereof.
Patent WO-2021211856-A1 (WO)
Title: Sec performance enhancing conditioning and storage solvents containing low levels of buffer and salt
Inventor: IRANETA PAMELA C
IPC: B01D15/20
Filed: 2021-04-15
Abstract: This disclosure pertains to performance enhancing conditioning and storage solvents containing low levels of buffer and salt for reproducible and improved size exclusion chromatography (SEC). In some embodiments, the present disclosure pertains to storage solvents for protein-based size exclusion chromatography that comprise water, a water-miscible organic solvent, a phosphate salt, and a neutral salt. In some embodiments, the present disclosure pertains to columns for protein-based size exclusion chromatography that comprise porous particles and such a storage solvent.
Patent WO-2021222861-A1 (WO)
Title: Anticorps spécifiques à abcb5 et leurs utilisations
Inventor: FRANK MARKUS H
IPC: C07K16/28
Filed: 2021-04-30
Abstract: L'invention porte sur des anticorps anti-ABCB5 possédant des activités de liaison et biologiques supérieures par rapport, par exemple, à des anticorps anti-ABCB5 disponibles dans le commerce et sur des compositions pharmaceutiques les comprenant. L'invention concerne également des applications thérapeutiques et de diagnostic de tels anticorps anti-ABCB5.
Patent WO-2021226060-A1 (WO)
Title: Formulations of hyaluronic acid and amniotic or gestational fluid, and uses of the same
Inventor: BERRY ROBERT
IPC: A61P19/04
Filed: 2021-05-04
Abstract: Methods of preparing a mixture of human amniotic fluid (and/or tissue or fluid of the placental/gestational area) and high molecular weight hyaluronic acid are described. The mixtures are amenable for long-term storage (e.g., at room temperature or with cryopreservation) with minimal loss of biological function. The mixtures are stable at room temperature. The formulations are useful for treating, for example, joint injuries, osteoarthritis, eye injuries, and cosmetic conditions.
Patent WO-2021236405-A1 (WO)
Inventor: LIM YEON-HEE
IPC: C07D487/04
Filed: 2021-05-13
Abstract: Invented are compounds of formula I and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are DGAT2 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, type-2 diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cognitive decline, dementia, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions, comprising administering a compound of Formula I to a patient in need thereof.
Patent WO-2021236461-A1 (WO)
Inventor: FERRONI PAOLO
IPC: C23C24/00
Filed: 2021-05-14
Abstract: Est divulgué un procédé de fabrication de tubes de gainage indépendants à structures multicouches. Selon le procédé, un substrat formant mandrin cylindrique et définissant un espace intérieur cylindrique creux est fourni. Un premier métal en poudre de pulvérisation à froid est sélectionné. Le substrat formant mandrin cylindrique est mis en rotation et le premier métal en poudre de pulvérisation à froid est appliqué sur une surface externe du substrat formant mandrin cylindrique pour former une première couche. Le substrat formant mandrin cylindrique est retiré.
Patent WO-2021252227-A1 (WO)
Title: Systems and methods for compression and encryption of data
Inventor: MCELVEEN CHRISTOPHER A
IPC: H04L29/06
Filed: 2021-06-01
Abstract: Systems and methods for compression and encryption of data are described herein. A method includes creating a plurality of hash table keys by applying a bit mask to an encryption key, applying a hashing function to the encryption key, creating a hash table using the hashing function, the hash table including the plurality of hash table keys and index values, the index values each identifying a location of data in the hash table connected to one of the plurality of hash table keys, receiving input data, and encoding the input data to generate encoded data, the encoding including both compression and encryption of the input data using the encryption key and the hash table.
Patent WO-2021262446-A1 (WO)
Inventor: TEHRANI SAM JAFARIAN
IPC: C23C16/455
Filed: 2021-06-10
Abstract: In some examples, an automated tilting system is provided for adjusting an orientation of a component in a substrate processing chamber. The automated tilting system comprises at least one tilt adjustment motor arranged to cooperate with the component and be connected to a portion of the component by a coupling. The coupling is configured such that automated rotational motion by the at least one tilt adjustment motor imparts corresponding axial movement, relative to the at least one tilt adjustment motor or a datum structure, to the connected portion of the component to adjust the orientation of the component in the processing chamber.
Patent WO-2022011315-A1 (WO)
Title: Ion current droop compensation
Inventor: BOWMAN CHRISTOPHER
IPC: H02M1/34
Filed: 2021-07-09
Abstract: In some embodiments, a high voltage power supply is disclosed that provides a plurality of high voltage pulses without any voltage droop between two subsequent pulses. In some embodiments, a high voltage power supply is disclosed that provides a waveform of voltage versus time having a plurality of high voltage pulses having a voltage greater than 1 kV and with a substantially flat portion between pulse. In some embodiments, a high voltage power supply is disclosed that includes a snubber with a snubber resistor having a resistance of about 7.5 mΩ - 1.25 Ω; and a snubber capacitor having a capacitance of about 2 μF - 35 μF.
Patent WO-2022031440-A1 (WO)
Title: Drug-specific pharmacokinetic assay for il-15 superagonist
Inventor: TANAKA SHIHO
IPC: G01N33/50
Filed: 2021-07-21
Abstract: Provided herein, are methods and compositions for detecting heteromeric protein complexes in biological samples. The methods and compositions allow for capturing and detecting the protein complex with substantially the same antibody, while avoiding detection of native proteins.
Patent WO-2022026517-A1 (WO)
Title: Pet food
Inventor: GARRETSON LISA
IPC: A23K40/30
Filed: 2021-07-28
Abstract: A pet food is described that has a veneer on a surface that is low in sugar, low in moisture, transport stable, and has a smooth appearance at room temperature. A veneer includes a non-fat solids content of about 40% to about 60% by weight of the veneer, and a fat composition in an amount of 35% to 60% by weight of the veneer.
Patent WO-2022026571-A1 (WO)
Inventor: SMITH JAMES A
IPC: E21B34/14
Filed: 2021-07-28
Abstract: A slurry outlet system including a top sub, a closure sleeve movable relative to the top sub between a closed position and an open position, a seal mounted on one or the other of the top sub or the closure sleeve, a protector sleeve disposed to cover the seal until displaced by one or the other of the top sub or the closure sleeve that does not include the seal during movement to the closed position. A method for pressure sealingly closing a slurry outlet system including bringing a closure sleeve into proximity with a top sub of the slurry outlet system, displacing a protector sleeve, with the closure sleeve, off a seal disposed about the closure sleeve and simultaneously making sealing contact between the top sub and the seal.
Patent WO-2022026792-A1 (WO)
Inventor: LI ZHI
IPC: H04N21/466
Filed: 2021-07-30
Abstract: In various embodiments, a data optimization application mitigates scoring inaccuracies in subjective quality experiments. In operation, the data optimization application generates a model that includes a first set of individual scores and a first set of parameters. The first set of parameters includes a first subjective score set and a first set of subjective factor sets. The data optimization application performs one or more optimization operations on the first set of parameters to generate a second set of parameters. The second set of parameters includes a second subjective score set and a second set of subjective factor sets, wherein the second subjective score set compensates for at least a first subjective factor set included in the second set of subjective factor sets. The data optimization application also computes a participant evaluation report based on at least a second subjective factor setsincluded in the second set of subjective factor sets.
Patent WO-2022035693-A1 (WO)
Inventor: KRISHNAN SHANKAR
IPC: H04W24/10
Filed: 2021-08-06
Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may measure quality of experience (QoE) metrics and transmit a QoE report that is formatted to be readable by a base station, such that a base station may receive the QoE report and independently perform adjustments associated with the service being utilized by the UE. A UE may receive a configuration message that includes a first configuration for reporting QoE measurements to a base station and a second configuration for reporting QoE measurements to a QoE server. The UE may measure one or more QoE metrics in accordance with the configuration message, and generate a first report for the base station based on the QoE measurements and the first configuration. Upon generating the report, the UE may transmit the first report to the base station in accordance with the first configuration.
Patent WO-2022047140-A1 (WO)
Title: Coring method and apparatus
Inventor: ZAINALABEDIN KHALID
IPC: E21B25/00
Filed: 2021-08-27
Abstract: A system includes a bottom hole assembly and a core sampling tool. The bottom hole assembly includes a housing and a drill bit coupled to the housing. The core sampling tool includes a first compartment positioned within the housing, the first compartment including a motor; a second compartment positioned within the housing and radially spaced apart from the first compartment, the second compartment including a coring bit; and a flexible drilling shaft extending between and coupled to the motor and the coring bit.
Patent WO-2022051244-A1 (WO)
Inventor: BAUDOT CHARLES
IPC: H01L31/0232
Filed: 2021-08-31
Abstract: A silicon-on-insulator (SOI) substrate includes a silicon dioxide layer and a silicon layer. A detection region receives a detected optical mode coupled to an incident optical mode defined by an optical waveguide in the silicon layer. The detection region consists essentially of an intrinsic semiconductor material with a spacing structure surrounding at least a portion of the detection region, which comprises p-type, n-type doped semiconductor regions adjacent to first, second portions, respectively, of the detection region. A dielectric layer is deposited over at least a portion of the spacing structure. The silicon layer is located between the dielectric layer and the silicon dioxide layer. First, second metal contact structures are formed within trenches in the dielectric layer electrically coupling to the p-type, n-type doped semiconductor regions, respectively, without contacting any of the intrinsic semiconductor material of the detection region.
Patent WO-2022066571-A1 (WO)
Inventor: HSIEH PEI-YING
IPC: A61M39/10
Filed: 2021-09-20
Abstract: A cannula for a vial adapter, having a pressure equalization device, includes a body having a first end, a second end positioned opposite the first end, and a sidewall extending between the first end and the second end. The body defines a central passageway extending from the first end to the second end of the body, with the body defining an opening extending through the sidewall of the body. The opening is in fluid communication with the central passageway. The second end of the body is closed.
Patent WO-2022072676-A1 (WO)
Title: Sump pump system and methods for removing synthetic ester-based fluids from an emulsion
Inventor: GANNON WILLIAM J
IPC: B01D17/04
Filed: 2021-09-30
Abstract: A polishing filter apparatus employed within a sump pump system for removing mineral oils, natural ester, and synthetic ester-based fluids from an emulsion is provided. The polishing filter apparatus is connected to a sump pump barrier via a polishing filter inlet conduit. Further conduit structures are disposed within the polishing filter apparatus, which lead into a polishing filter cartridge. The polishing filter removes excess synthetic ester-based fluids from a water/oil emulsion fluid flowing therethrough and releases a resultant filtered fluid. The polishing filter cartridge contains a filtration media with a hydrophilic composition for the capture of synthetic ester-based fluid having a surface tension dissimilar to water, and the hydrophilic composition of the media has a surface energy greater than or equal to 35 dynes per centimeter.
Patent WO-2022076847-A1 (WO)
Title: Procédés, systèmes et dispositifs de traitement de données de séquence
Inventor: ASKOVICH PETER
IPC: G16B30/00
Filed: 2021-10-08
Abstract: Des modes de réalisation de la présente divulgation concernent des systèmes, des appareils, des dispositifs et des procédés de traitement de données de séquençage permettant de déterminer l'identité de fragments d'ADN à partir d'une pluralité de lectures contenues dans un fichier de données de séquençage.
Patent WO-2022082094-A1 (WO)
Title: Système de réfrigération co2 avec régulation externe du liquide de refroidissement
Inventor: MARTIN J SCOTT
IPC: F25B1/10
Filed: 2021-10-18
Abstract: Système de refroidissement comprenant un sous-système de refroidissement et un sous-système de liquide de refroidissement. Le sous-système de refroidissement est conçu pour faire circuler un liquide de refroidissement entre un évaporateur (12, 22) contenant un liquide de refroidissement absorbant la chaleur et un refroidisseur/condenseur de gaz (2) contenant un liquide de refroidissement rejetant la chaleur pour refroidir un espace à température régulée. Le sous-système de refroidissement comprend un échangeur de chaleur (62) couplé au sous-système de refroidissement à une sortie du refroidisseur/condenseur de gaz et conçu pour transférer la chaleur du liquide de refroidissement sortant du refroidisseur/condenseur de gaz à un liquide de refroidissement externe lorsque le liquide de refroidissement externe s'écoule à travers l'échangeur de chaleur, une vanne de commande (64), et un dispositif de commande (50) conçu pour actionner la vanne de commande afin de commander un écoulement d'au moins l'un du liquide de refroidissement ou du liquide de refroidissement externe à travers l'échangeur de chaleur en fonction d'une température du liquide de refroidissement externe par rapport à une température du liquide de refroidissement sortant du refroidisseur/condenseur de gaz.
Patent WO-2022087390-A1 (WO)
Inventor: AKL NAEEM
IPC: H04W40/22
Filed: 2021-10-22
Abstract: Procédé et appareil pour réécrire des en-têtes BAP dans des réseaux IAB. L'appareil reçoit, en provenance d'une seconde station de base, une configuration de routage indiquant un mappage entre un premier ID de routage et un second ID de routage. L'appareil reçoit un paquet avec un en-tête de paquet indiquant le premier ID de routage. L'appareil détermine le second ID de routage sur la base de la configuration de routage mettant en correspondance le premier ID de routage dans l'en-tête de paquet avec le second ID de routage. L'appareil modifie, sur la base d'une détermination du second ID de routage, l'en-tête de paquet pour remplacer le premier ID de routage avec le second ID de routage. L'appareil transmet le paquet sur la base du second ID de routage.
Patent WO-2022125859-A1 (WO)
Inventor: MCDOWELL SEAN M
IPC: A61F5/01
Filed: 2021-12-10
Abstract: Instrument de massage comprenant un corps rigide ayant un premier pic et un second pic, le premier pic et le second pic étant situés approximativement le long d'une ligne centrale du corps rigide et un espacement existant entre le premier pic et le second pic. Une hauteur du premier pic peut être différente d'une hauteur du second pic. Une structure de support inférieure peut être disposée sous le corps rigide, façonnée pour fournir une surface de repos stable au corps rigide, et conçue pour recevoir une ou plusieurs pattes de support extensibles dans une position rétractée. Une pluralité de creux peu profonds peuvent former la surface du corps rigide. La ou les pattes de support extensibles peuvent être fixées à une partie de la structure de support inférieure, tel qu'au niveau d'un point d'articulation et conçues pour se rétracter sous le corps rigide.
Patent WO-2022132668-A1 (WO)
Title: Spatial averaging method for coherent distributed sensing
Inventor: HU JUNQIANG
IPC: G01D5/353
Filed: 2021-12-13
Abstract: Aspects of the present disclosure describe systems, methods and structures for coherent distributed sensing that employs a moving average method among locations along a sensing fiber employing a user configured number of taps that involves location grouping and a groups internal phase alignment followed by an inter-group phase alignment and combining. Our method employs two steps of rotation to achieve the alignment: intra-group rotation and inter-group rotation to align the phase of all participating sensing fiber locations
Patent WO-2022133262-A1 (WO)
Inventor: KLEINBERG ANDREW
IPC: G01N30/02
Filed: 2021-12-17
Abstract: L'invention concerne des procédés d'identification d'une ou de plusieurs liaisons disulfure non natives dans une biomolécule (e.g, un anticorps) Selon un mode de réalisation représentatif, un procédé comprenant l'exécution d'une digestion de la biomolécule dans des conditions non réductrices pour fournir un échantillon comprenant une pluralité de fragments de biomolécule, la mise en contact de l'échantillon avec une colonne de séparation, l'application d'un premier gradient de phase mobile comprenant de l'acide trifluoroacétique (TFA) et d'un additif de petite molécule à la colonne de séparation, l'application d'un second gradient de phase mobile comprenant du TFA dans de l'acétonitrile (ACN) et d'un additif de petite molécule à la colonne de séparation, la réalisation d'une procédure de réduction partielle sur l'échantillon élué, l'application des composants d'échantillon élués partiellement réduits à un spectromètre de masse, et la réalisation d'une analyse par spectrométrie de masse sur les composants d'échantillon élués partiellement réduits pour identifier ladite une ou lesdites liaison(s) disulfure non natives dans la biomolécule.