baber/WOPTO huggingface dataset:
Patent DE-68923274-T2 (DE)
Inventor: GOEDEMANS WILHELMUS
IPC: A61K51/08
Filed: 1989-02-08
Granted: 1995-11-09
Abstract: The invention relates to a method of preparing a protein or a proteinaceous material labelled with a metal-radionuclide and intended for diagnostic or therapeutic application, by reacting a protein or a proteinaceous material with an agent for coupling the radionuclide to the protein or the proteinaceous material, a protein conjugate being formed, and by then complexing the radionuclide with the conjugate thus formed to a radionuclide complex. A coupling agent is used which consists at least substantially of a thio compound of the general formula Y-R-S-X, wherein X is a hydrogen atom or a suitable protective group, R is a branched or non-branched, optionally substituted hydrocarbon radical having 1-10 carbon atoms, which may be interrupted by one or more hetero atoms, and Y is at least one terminal reactive group capable of reacting with a functional group from the protein or the proteinaceous material; or a cyclic condensation product of the thio compound of formula (I) having 5-7 ring atoms, wherein X and Y together constitute a reactive group capable of reacting with a functional group from the protein or the proteinaceous material; or a water-soluble salt of this condensation product. The invention also relates to novel compounds useful as coupling agents and protein conjugates made from them. The invention further relates to the labelled protein or proteinaceous material thus obtained and to a kit for the preparation of a radiopharmaceutical composition which comprises a protein conjuguate formed by reaction of a protern or a proteinaceous material with the coupling agent mentioned hereinbefore.
Patent DE-68925798-T2 (DE)
Inventor: CLARK ALAN DOUGLAS
IPC: H03M7/30
Filed: 1989-12-08
Granted: 1996-09-19
Abstract: In a data compression system including a dynamically compiled dictionary the dictionary is updated by storing a string comprising a word and a part-word. The part-word comprises a plurality of characters from the string immediately following the word in the input stream. The system may use a Mayne single-pass data compression algorithm. In a system using the Mayne algorithm after each string is matched the corresponding index is transmitted.
Patent DE-69001125-T2 (DE)
Inventor: DELPRATO FRANCOIS
IPC: C01B39/08
Filed: 1990-08-01
Granted: 1993-10-07
Abstract: PCT No. PCT/FR90/00583 Sec. 371 Date Apr. 1, 1991 Sec. 102(e) Date Apr. 1, 1991 PCT Filed Aug. 1, 1990 PCT Pub. No. WO91/01940 PCT Pub. Date Feb. 21, 1991.Disclosed is a process for the preparation of zeolites having a gallosilicate skeleton and belonging to the structural class of faujasite in which there is first formed a precursor of the zeolite which entraps a structuring agent which is thereafter destroyed by calcining wherein the structuring agent is at least one compound belonging to the group formed by carbon-containing rings and macrocycles whose ring comprises at least 6 atoms and contains heteroatoms selected from oxygen, nitrogen and silicon.
Patent DE-69006519-T2 (DE)
Inventor: BENE PIERRE YVES
IPC: A61B19/00
Filed: 1990-01-19
Granted: 1994-08-18
Abstract: This device comprises a tubular body (2) into which open discharge nozzles (5) for an atomized product constituted by disinfection liquid and pressurized air. The air supply means of the injectors comprise an annular duct (14) extending through 360 DEG  and directly supplying the injectors (6), while the liquid supply means of the injectors comprise several stages (15,17) with the fluid vein separated in two at each stage.
Patent DE-69009493-T2 (DE)
Inventor: WAETJEN FRANK
IPC: A61P25/00
Filed: 1990-11-22
Granted: 1994-12-08
Abstract: New imidazoquinoxaline compounds having the general formula I <IMAGE> (I)  wherein  <IMAGE>  wherein R1 and R2 independently are hydrogen, straight or branched C1-6-alkyl, or C3-7-cycloalkyl; R3 is hydrogen, straight or branched C1-6-alkyl, straight or branched C2-6-alkenyl, or aralkyl or aroylalkyl which may optionally be substituted with halogen or C1-6-alkoxy; R4 and R5 independently are hydrogen, halogen, C1-6-alkyl or trifluoromethyl. The compounds are useful in psychopharmaceutical preparations as anticonvolusants, anxiolytics, hypnotics and in improving the cognitive function of the brain of mammals.
Patent DE-69013713-T2 (DE)
Inventor: PRITCHARD ADRIAN MARCUS
IPC: G09F15/00
Filed: 1990-01-08
Granted: 1995-04-06
Abstract: A display panel assembly comprising at least two frames (10) each having uprights (12) on opposite sides thereof, the uprights of adjacent frames having pivotal interconnections (16) to enable the frames to be variably angled relative to one another. The frames (10) also have top and bottom cross members (14), the uprights and cross members each having a pair of projecting ribs defining a panel receiving slot around the inside edge of the frame in the median plane of the frame, and the cross members also having lips (54) which define top and bottom panel receiving slots on both sides of the median plane.
Patent DE-69017723-T2 (DE)
Inventor: JANSSEN ROBERT A
IPC: G02C7/04
Filed: 1990-01-04
Granted: 1995-08-03
Abstract: Process for treating hydrophobic polymer surfaces to form hydroxyl moieties thereon comprises ozonating the surface of said hydrophobic polymer to form hydroperoxy groups thereon, and then irradiating said ozonated surface with ultraviolet light or exposing to heat to convert the hydroperoxy groups to hydroxyl moieties in the presence of a hydrogen donor. Such hydroxylated surfaces possess hydrophilic properties and can undergo the chemical reactions characteristic for hydroxyl groups. Polymers so modified are useful in biomedical devices, semipermeable membranes, films, fibers and especially contact lenses.
Patent DE-69028387-T2 (DE)
Inventor: MAITRE BRUNO PIERRE
IPC: B60C11/03
Filed: 1990-12-18
Granted: 1997-03-20
Abstract: A tire tread of elastomeric material formed into ground engaging elements (1) is provided with sipes (2) in said elements. The sipes are in the form of incisions. A first incision portion(s) extends inwardly from the tread surface and then splits into at least two incision portions (3,4) which continue to extend away from the tread surface while at the same time diverging apart from one another.
Patent DE-69029335-T2 (DE)
Inventor: SEXTON MICHAEL DAVID
IPC: C10L1/183
Filed: 1990-03-01
Granted: 1997-04-03
Abstract: Sediment and colour formation in distillate fuels are reduced by the addition of a quaternary ammonium compound comprising a cation in which the ratio of carbon atoms to quaternary nitrogen atoms is not more than 10:1 and an anion which is derived from an acid which is a carboxylic acid, carboxylic acid anhydride, phenol, sulphurized phenol or sulphonic acid.
Patent DE-69102277-T2 (DE)
Inventor: FRUCHART DANIEL
IPC: H01F1/057
Filed: 1991-06-28
Granted: 1994-09-15
Abstract: A method for improving the magnetic properties of a polyphase product having permanent-magnet-like properties at room temperature, acting as a precursor and having been processed by hydridizing crackling at a low pressure and a low temperature to obtain an intermediate hydride in powdered form. According to the method, the intermediate hydride in powdered form undergoes, after hydridizing, a first partially dehydridizing heat treatment in a vacuum and at a low temperature below its segregation temperature, and the non-segregated product thereby obtained undergoes a second, subsequent intense dehydridizing heat treatment in a vacuum and at a temperature of around 600 C.
Patent DE-69106482-T2 (DE)
Inventor: VERHEYEN WILLY
IPC: B65D5/54
Filed: 1991-10-21
Granted: 1995-07-06
Abstract: Reclosable easy-opening box (1) comprising two opposite longitudinal lateral faces (3,5) and two opposite transverse lateral faces (7,9) binding both said longitudinal faces (3,5) the transverse faces (7,9) bearing each via a folding line (28,30,48, 50) a transverse bottom flap (27, 29) and a transverse cover flap (47,49) the width of which substantially corresponds to the width of the corresponding transverse face (7,9), the longitudinal faces (3,5) bearing each via a folding line (24,26,44,46) a longitudinal bottom flap (23,25) and longitudinal cover flap (43,45) the width of which substantially corresponds to the width of the corresponding longitudinal face (3,5), at least one cover flap, called overlapping flap, being designed to overlap at least another flap(s) when the box (1) is closed, wherein at least the overlapping flap (43) or flaps (43,45) is/are equipped with at least one partially precut line (41,42;61,62,71,72), that is interrupted by a sinusoidal section of partially precute line, at least the area of the overlapping flap (43) or flaps (43,45) defined by the said partially precut line (41,42;61,62,71,72) and the side edges being assembled with underlying flap(s) (45;47,49) under prestress. <IMAGE>
Patent DE-69109970-T2 (DE)
Inventor: THUNBERG JON C
IPC: C07C227/16
Filed: 1991-08-15
Granted: 1995-09-21
Abstract: A process of preparing iron chelates of amino and hydroxy carboxylic acids, comprising reacting an oxide of iron with an amino or hydroxy carboxylic acid and a base in the presence of ferrous ion or metallic iron as a catalyst. Additional base is added to the resulting chelant and oxidation may be carried out to convert any ferrous ion to ferric.
Patent DE-69110524-T2 (DE)
Inventor: HOGG CLIVE LAURENCE
IPC: G02B6/44
Filed: 1991-04-09
Granted: 1995-11-30
Abstract: In a simple and inexpensive method of manufacturing a composite electric and optical cable incorporating a flexible tube having a flexible optical waveguide 6 loosely housed in the bore of the tube, the flexible electric cable 10, without a flexible optical guide loosely housed in the bore of the flexible tube 5, is wound around the hub of a cable drum 14 in such a way that each end of the wound cable is exposed and accessible. The flexible optical guide 6 is then accommodated in the bore of the flexible tube 5 of the wound cable 10 by introducing a leading end of the optical guide into the end of the bore of the flexible tube at one exposed end 11 of the wound cable and by propelling the optical guide along the bore of the wound cable by fluid drag of a gaseous medium which is passed through the bore in the desired direction of advance at such a pressure that the optical guide is carried along the bore until the optical guide is loosely housed in and throughout the length of the bore of the flexible tube of the wound cable. <IMAGE>
Patent DE-69121499-T2 (DE)
Inventor: SCHMIDHAUSER ALBERT
IPC: A61H7/00
Filed: 1991-09-20
Granted: 1997-03-27
Abstract: This scalp massaging device consists of a helmet (1) equipped with three first fixed points of contact (5) with the scalp of the user which are situated near the top of the helmet. It moreover comprises three second points of contact (8), one in the frontal zone of the helmet and the others in the parieto-temporal zones of the latter, these second points of contact comprising means (17, 18) making it possible to apply it to the scalp with a specific and adjustable pressure. Finally, the helmet moreover has an eccentric (26) driven in rotation by a motor. 
<IMAGE>
Patent DE-69124614-T2 (DE)
Inventor: AR-FU LAM PETER
IPC: A47G25/20
Filed: 1991-12-23
Granted: 1997-07-10
Abstract: A clothes hanger in which each hanger arm is adjustable in length by means of an extender arm (6) mounted for and operated by a mechanical system so that the extender arms (6) move simultaneously either inward or outward by the same distance. The mechanical system may be hand operated or driven by an electric motor (16). <IMAGE>
Patent DE-69132141-T2 (DE)
Inventor: CHENARD LEO
IPC: C07D413/06
Filed: 1991-03-04
Granted: 2000-09-21
Abstract: PCT No. PCT/US91/01470 Sec. 371 Date Nov. 6, 1992 Sec. 102(e) Date Nov. 6, 1992 PCT Filed Mar. 4, 1991 PCT Pub. No. WO91/17156 PCT Pub. Date Nov. 14, 1991.5-(1-Hydroxy-2-piperidinopropyl)-2(1H,3H)-indolone derivatives and analogs; pharmaceutical compositions thereof; methods of treating CNS disorders therewith; and intermediates useful in the preparation of said compounds.
Patent DE-69200389-T2 (DE)
Inventor: GUILLAUMET GERALD
IPC: C07D335/06
Filed: 1992-06-30
Granted: 1995-04-27
Abstract: Process for the preparation of enantiomers of general formula (I): <IMAGE>  where Z, R1, R2, R3 and n are defined in the description. The derivatives obtained according to the invention are useful as medicaments.
Patent DE-69204940-T2 (DE)
Inventor: KANE ROBERT C
IPC: H01J9/02
Filed: 1992-08-10
Granted: 1996-05-15
Abstract: A field emission electron emitter employing a coating of diamond material (406) disposed on a surface of a layer of conductive/semiconductive material (407) is constructed by a method including the steps of implanting carbon ions (404) at a surface of a selectively shaped substrate (401) to function as nucleation sites for the diamond formation. A conductive layer (407) is deposited over the diamond (406) and the substrate (401) is removed to leave an electron emitter with a diamond coating. <IMAGE>
Patent DE-69206108-T2 (DE)
Inventor: VANDER HEYDEN WILLIAM H
IPC: G01F1/32
Filed: 1992-12-16
Granted: 1996-04-18
Abstract: A vortex flowmeter has an elongated vortex generator in the flow passage of a body and transverse to the direction of flow. A first wing is located in the flow passage downstream of the generator and a second wing is located downstream from the first wing. A sensor is associated with each wing to provide a signal responsive to movement of the wing, and the signals are combined to have external noise components of the signals cancel each other. <IMAGE>
Patent DE-69209923-T2 (DE)
Inventor: NAKANISHI TAKASUKE
IPC: A61C1/08
Filed: 1992-08-11
Granted: 1996-09-19
Abstract: A cartridge type dental handpiece (10) contains a handpiece main body (11), a head housing (12) provided at a distal end of the handpiece main body (10), and a cartridge (13) detachably adapted within the head housing (12). The cartridge (13) has a cartridge casing (26) and a rotatable sleeve (23) rotatably mounted within the cartridge casing (26) and adapted for detachably holding a dental burr (15). The dental handpiece (10) further contains a fluid passage (17, 18, 20, 21) defined between an inner surface of the head housing (12) and an outer surface of the cartridge casing (26) when the cartridge (13) is mounted within the head housing (12), a fluid spraying port (22) formed in a lower surface of the cartridge casing (26) in communication with the fluid passage (17, 18, 20, 21) for spraying the fluid from the fluid passage (17, 18, 20, 21) onto a tooth being treated, and a communication port (31, 32) for supplying the fluid from a fluid supply duct (29, 30) within the handpiece main body (11) into the fluid supply passage (17, 18, 20, 21). <IMAGE>
Patent DE-69214043-T2 (DE)
Inventor: MAGGIONI ROBERTO
IPC: B65G27/34
Filed: 1992-07-20
Granted: 1997-04-17
Abstract: The multiple-channel vibrating feeding table includes a table (1) provided with a plurality of mutually adjacent troughs which define the channels for conveying loose parts, motor elements (10,17,18) for vibrating the table, and elements (20-22,25-27) for connecting each of the troughs to the motor elements, the connecting elements being individually actuatable in order to vibrate only selected trough or troughs. <IMAGE>
Patent DE-69214205-T2 (DE)
Inventor: WAETJEN FRANK
IPC: A61K31/40
Filed: 1992-07-07
Granted: 1997-02-06
Abstract: A compound having the formula <CHEM>  wherein  R<1> is C1-6-alkyl which may be branched or cyclic;  R<2> is C1-6-alkyl which may be branched or cyclic; or wherein R<1> and R<2> together represent -(CH2)n-, wherein n is 3, 4, 5. and a method of treating disorders of a mammal, including a human, responsive to the blockade of glutamic and aspartic acid receptors, with the same.
Patent DE-69220455-T2 (DE)
Inventor: MARKUS PAUL HENRY
IPC: A23L27/20
Filed: 1992-11-05
Granted: 1997-11-27
Abstract: A process for the preparation of phenylaldehydes, in particular vanillin by converting compounds having the formula <CHEM>  wherein  R1 = H, OH, OCH3 and C1-4 alkyl,  R3 = H, OH, OCH3 and C1-4 alkyl, and  R2 = H, C1-6 alkyl, -CH2OH, -COOH, -OCH3 and -CH20-R4, wherein  R4 = benzoyl or C1-4 alkanoyl or  R2 = -CO-CH2-CO-; the last radical combining two structures having formula I or its tautomeric isomers in the presence of the enzyme lipoxidase (EC 1.13.11.12) (also called lipoxygenase) into the phenylaldehyde compounds having the formula <CHEM> wherein R1 and R3 have the meanings indicated above. i
Patent DE-69223807-T2 (DE)
Inventor: FISCHER DANIEL
IPC: F01N3/20
Filed: 1992-03-17
Granted: 1998-07-23
Abstract: An auxiliary catalytic converter (11) for treating exhaust gas pollutants from an internal combustion engine during warm-up comprises a housing (13) which defines an exhaust gas receiving chamber (15), an exhaust gas inlet (17) in one end of the housing and an exhaust gas outlet (19) at the other end of the housing, a hollow catalyst structure (23) having discrete channels or pores secured in the chamber spaced from the walls of the housing and aligned axially providing a passage (25) between the outer surface of the catalyst structure and the wall and an axial channel (27) in communication with the gas inlet and gas outlet, and valve means (41) adapted to be opened and closed in response to a predetermined condition, the valve means when in a closed position restraining exhaust gas flow in the axial channel causing the gas to flow radially through the catalyst structure into the passage and when in an open position permitting essentially unimpeded flow of gas from the gas inlet through the axial channel to the gas outlet.
Patent DE-69301360-T2 (DE)
Inventor: YAMAMOTO NORIKO
IPC: C07D417/04
Filed: 1993-02-25
Granted: 1996-07-11
Abstract: A neuroprotecting drug comprises as an essential active ingredient ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]pyrrol-1-yl acetate, which is useful with high safety for the prophylaxis and treatment of brain dysfunction induced by hypoxia due to the distrubance of cerebral circulation such as cerebral hemorrhage or cerebral infarction in human being.
Patent DE-69307739-T2 (DE)
Inventor: HOLMGREN BERTIL
IPC: B65D55/02
Filed: 1993-03-23
Granted: 1997-05-28
Abstract: PCT No. PCT/SE93/00241 Sec. 371 Date Sep. 22, 1994 Sec. 102(e) Date Sep. 22, 1994 PCT Filed Mar. 23, 1993 PCT Pub. No. WO93/19268 PCT Pub. Date Sep. 30, 1993Safety device to be mounted on a parallelepipedic box comprises a frame (10) constructed to encircle the box and having an insert opening (11) for the box and a blocking element (13) displaceably and pivotably mounted to the frame, the blocking element being adjustable between a blocking position and an off position to prevent in the blocking position the box inserted into the frame from being withdrawn from the frame. A spring blade (22) clamped at one end thereof in the blocking element extends in the displacement path of the blocking element to engage at the other, free end thereof behind a shoulder (25) on the frame and thus to prevent displacement of the blocking element in the blocking position, wherein positive engagement is established between the blocking element and the frame in order to prevent the blocking element from pivoting. The spring blade can be actuated by external assembly in order to release the blocking element for adjustment to the off position by displacement or pivotal movement and thus allowing the box to be withdrawn from the frame through the insert opening.
Patent DE-69326386-T2 (DE)
Inventor: WALSER ARMIN
IPC: C07D487/04
Filed: 1993-06-09
Granted: 2000-06-15
Abstract: The present invention is directed to imidazo[1,5-a] [1,4]benzodiazepine-3-carboxamide compounds of the formula: <CHEM> wherein R is hydrogen, CH3CH2-, CH2=CHCH2-, (CH3)2CH-, CH3CH2CH2-, or   <CHEM> or a pharmaceutically acceptable salt thereof. These compounds and their pharmaceutically acceptable salts possess anti-anxiety and anti-epileptic activity.
Patent DE-69330546-T2 (DE)
Inventor: MERKSTEIJN JACOBUS L VON
IPC: B21D53/00
Filed: 1993-11-30
Granted: 2002-05-08
Abstract: The invention relates to metal rod (1) with a substantially round cross section comprising at least six rows (16,17) of ribs (11) arranged in the surface spread over the periphery, the surface of which is preferably provided with six rows of ribs (11) and the ribs (11) of at least one row are optionally arranged obliquely in the surface relative to the rod direction, wherein the ribs of adjoining rows of ribs are optionally oriented in herringbone form. <IMAGE>
Patent DE-69409913-T2 (DE)
Inventor: CULLINAN GEORGE JOSEPH
IPC: A61K31/40
Filed: 1994-10-13
Granted: 1998-09-24
Abstract: Methods of inhibiting smooth muscle cell proliferation and restinosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula <CHEM>  or <CHEM>     wherein R1 and R3 are independently hydrogen, -CH3, <CHEM>  or <CHEM>  wherein Ar is optionally substituted phenyl;     R2 is <CHEM>  and R4 is hydrogen or -OR1, and pharmaceutically acceptable salts and solvates thereof. Also provided is a method for inhibiting restinosis.
Patent DE-69418176-T2 (DE)
Inventor: UCHIDA HIROSHI
IPC: B28B1/29
Filed: 1994-08-31
Granted: 1999-09-09
Abstract: A method of manufacturing a pattern-carrying molded product (5), comprising the steps of supplying a predetermined amount of dry powder material (2) onto the portion of a reference surface (7) which corresponds to a pattern (6) to be formed; forming by using an angle-of-repose forming member the powder material, which is thus supplied, into a layer of powder material with a side surface having an inclined surface (8) of an angle of repose corresponding to a pattern to be formed; supplying a predetermined amount of adifferent dry powder material (3) onto the remaining portion of the reference surface; and solidifying the resultant product unitarily as it is or with a lining layer (4) laminated. <IMAGE>
Patent DE-69503129-T2 (DE)
Inventor: HAWKINS MARY
IPC: C07H19/167
Filed: 1995-04-25
Granted: 1999-02-18
Abstract: The invention provides novel pteridine nucleotides which are highly fluorescent under physiological conditions and which may be used in the chemical synthesis of fluorescent oligonucleotidcs. The invention further provides for fluorescent oligonucleotides comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures.
Patent DE-69511739-T2 (DE)
Inventor: WALCH MARTIN
IPC: A01D34/66
Filed: 1995-01-27
Granted: 2000-04-27
Abstract: The mower consists of a cutter bar (2) supporting cutting elements (7) which rotate about vertical axes (15) by use of shafts (11) with ends rotating in the cutter-bar housing (4) and a supporting structure (3) with a lengthwise member (28) and a leg (29). The lengthwise member and leg are joined by a connector (35) with elements (36) permitting the rotation and lengthwise movement during assembly of a horizontal axle (37) which lies parallel to a plane containing the axes (15) of the cutting elements (7). The connector also has an immobiliser (38) to lock the horizontal axle (37). The lengthwise member (28) has a cover (39), with the leg situated between its side panels and connected to them by a pivot.