baber/WOPTO huggingface dataset:
Patent NZ-211221-A (NZ)
Title: Closure: tear band connected by thin web with spaced apart stronger nibs
Inventor: STUBBS P
IPC: B65D41/48
Filed: 1985-02-25
Abstract: A container closure has a cap part which can be removed from and replaced upon an associated container as required and a tamper evident tear band 3 which has to be removed from the closure before the cap part can be initially removed from the container. The tear band 3 is connected to the skirt 2 of the cap part by a number of spaced apart relatively strong frangible nibs 6, the spaces between the nibs being each filled by a relatively weak thin web 7 of material.
Patent NZ-214570-A (NZ)
Title: Homonojirimycin glycosides and pharmaceutical compositions
Inventor: LIU P S
IPC: C07H15/26
Filed: 1985-12-16
Abstract: Homonojirimycin glycosides active as inhibitors of carbohydrate digestive enzymes are described herein. The compounds are prepared by the reaction of an appropriately protected homonojirimycin with a protected glycosyl halide followed by removal of the protecting groups.
Patent NZ-214928-A (NZ)
Title: Homo and copolymers of ethylene formed by solution polymerisation process
Inventor: ZBORIL V G
IPC: C08F2/42
Filed: 1986-01-24
Abstract: A solution polymerization process for the preparation of high molecular weight homopolymers of ethylene and copolymers of ethylene and C4 - C12 alpha-olefins comprises feeding monomer(s), coordination catalyst and inert hydrocarbon solvent to a reactor, polymerizing the monomers at a temperature of up to 320 DEG C and a pressure of less than 25 MPa, and deactivating the catalyst in the solution so obtained. The catalyst is deactivated by sequentialiy admixing therewith a minor amount of a deactivating agent followed by a solution of a salt of an alkaline earth metal or zinc and an aliphatic mono-carboxylic acid dissolved in hydrocarbon solvent. The deactivating agent is selected from carbon dioxide, carbon monoxide, dialkyl carbonate and dioxolones. The hydrocarbon solvent and other volatile matter are then separated from the resultant solution and a composition comprising said high molecular weight polymer is recovered. The amount of said deactivating agent is not more than 2.5 moles of deactivating agent per mole of halogen plus alkyl radicals in the coordination catalyst.
Patent NZ-218795-A (NZ)
Inventor: KASZTREINER E
IPC: C07D498/04
Filed: 1986-12-23
Abstract: The invention relates to novel pyrimido [5,4-b][1,4]oxazine derivatives of the formula (I), and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I)    <IMAGE>  (I)  wherein R1 stands for a C1-4 alkyl group; R2 stands for hydrogen or halogen or an azido group or an -NR5R6 group, wherein R5 represents hydrogen or a benzyl group, or a C1-4 alkyl group unsubstituted or substituted by a hydroxyl group, R6 stands for hydrogen, an amino group, a C3-6 cycloalkyl group, a straight or branched-chain C1-4 alkyl group optionally substituted by a hydroxyl, mercapto, aminocarbonyl, furyl, 2-benzo[1,4]dioxanyl, di(C1-4 alkyl)amino group or by a phenyl or phenoxy group optionally mono- or polysubstituted by halogen or C1-4 alkoxy group (s) or by a 6-membered, saturated nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C1-4 alkyl or benzyl group; further NR5R6 may also represents a 6-membered, saturated, nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C2-4 alkoxycarbonyl or C1-4 hydroxyalkyl group; R3 and R4 are the same or different and stand for hydrogen or a C1-4 alkyl group; R9 stands for hydrogen or a C1-4 alkyl group unsubstituted or monosubstituted by an oxo, cyano, aminocarbonyl, C2-5 alkoxycarbonyl, pyridiyl, morpholinocarbonyl, or phenyl group or mono- or polysubstituted by OH group(s), with the proviso that R2 is different from chlorine, 4-morpholinyl and piperidyl group when R9 stands for hydrogen; or R2 is different from chlorine and 4-morpholinyl group when R9 stands for a methyl or benzyl group. The compounds of the formula (I) are capable to increase the myocardial contractile force (the performance of the failing heart) and the coronary blood flow, thus they can therapeutically be used for the treatment of the chronic heart failure and coronary disturbances.
Patent NZ-221105-A (NZ)
Title: Aqueous solutions of acids or acidic salts thickened with amino derivatives
Inventor: SILVESTER R N
IPC: C11D7/08
Filed: 1987-07-17
Abstract: A thickened aqueous composition comprising at least one compound acid or acidic salt, a thickening agent which is at least one of the compounds selected from the group consisting of compounds of the formula: <CHEM> wherein R, R1 R2, R3, R4 and R5 are specified substituent groups, and optionally a strong ionic salt, the thickening agent and the acid or acidic salt being together substantially water soluble, and wherein the thickened aqueous composition has a viscosity of not less than 30 centipoise at 25 DEG C when measured with a Brookfield RVT viscometer at 50 rpm using a No. 1 spindle.
Patent NZ-226815-A (NZ)
Title: Arachidonic acid derivatives and pharmaceutical compositions
Inventor: DUCEP JEAN BERNARD
IPC: C07F7/18
Filed: 1988-11-02
Abstract: Fluorinated arachidonic derivatives are 5-lipoxygenase inhibitors which have the useful pharmacologic activity as antiallergy and anti-inflammatory agents and are useful for treating, for example, asthma, anaphylaxis, allergy, rheumatoid arthritis, and psoriasis.
Patent NZ-227291-A (NZ)
Title: Laminates containing a metal foil layer for packaging materials with a volatile component
Inventor: SCHAEFER SUZANNE E
IPC: B32B15/08
Filed: 1988-12-12
Abstract: Sheet materials and packages made therefrom, and capable of holding hard-to-hold products such as methyl salicylate and other volatile components, in one form include a foil layer (12) and a layer (14) of EVOH between foil layer (12) and the enclosed product. A carboxy-modified adhesive layer (18) is disposed between the EVOH layer (14) and the product. Additional layers (28, 30, 32, 34, 36, 38, 40) are used in the sheet material for purposes of adhesion, appearance, protection, body, and the like. A coextruded film structure comprises an EVOH layer (514), a surface layer (516), an intervening adhesive layer (518), and a fourth covering layer (519) for covering and protecting the EVOH layer (514), especially from physical abuse. Packages made from the sheet materials and coextruded film can be in the form of sachets, pouches and bags, or in the form of dispensing tubes.
Patent NZ-241029-A (NZ)
Title: Peptides with cysteine residue or dimers thereof with insulin activity and pharmaceutical compositions
Inventor: MULLNER STEFAN
IPC: A61K38/08
Filed: 1991-12-17
Abstract: Short peptides of the formula I X-Y-A-B-C-Cys-D-E (I> in which A and B are an amino acid or a covalent bond, C and D are an amino acid or a substituted amino acid, E is a modified or unmodified amino acid or a covalent bond, X is a radical or hydrogen and Y is leucine or a covalent bond, or dimers of the peptides of the formula I with cystine as dimerisation component, the stereoisomeric forms thereof where appropriate or their physiologically tolerated salts, the preparation thereof, and their use for the treatment of diabetes mellitus are described.
Patent NZ-246515-A (NZ)
Title: Animal transporter; upper portions of side walls constrain sideways movement of animals upper body and the lower wall portions diverge from side wall upper portions
Inventor: CHATTERTON JOHN
IPC: B60P3/04
Filed: 1993-01-07
Abstract: PCT No. PCT/AU93/00008 Sec. 371 Date Oct. 13, 1994 Sec. 102(e) Date Oct. 13, 1994 PCT Filed Jan. 7, 1993 PCT Pub. No. WO93/13959 PCT Pub. Date Jul. 22, 1993.A transportable animal enclosure assembly including opposed longitudinal sidewall assemblies each having a respective upper portion adapted to constrain sideways movement of the upper body portion of an animal being transported and a base wall extending between and laterally beyond the upper portions and being accessible to the animal transported. One or both sidewall assemblies preferably include a lower portion that slopes inwardly from the base wall to the upper portion. The transportable animal enclosure preferably includes adjustable rear support for supporting the rump of the animal and an adjustable chest restrainer for restraining the animal against the rear support.
Patent NZ-314517-A (NZ)
Title: 1-substituted phenyl-4,5-dihydro-3H-2,3-benzodiazepine derivatives and pharmaceutical compositions thereof
Inventor: LING ISTWAN DR
IPC: A61P21/02
Filed: 1997-04-03
Abstract: A compound of formula I or an isomer or an acid addition salt thereof is claimed wherein: R1 and R2 are independently hydrogen, halo, alkyl, alkoxy, nitro, trifluoromethyl or -NR8R9; R3 is alkyl, cycloalkyl or -CO-R13; R4 and R5 are independently hydrogen or alkyl; R6 and R7 are independently hydrogen, chloro or bromo and R8, R9 and R13 are as defined in the specification provided that if R6 and R7 are H then the other is different from H. A pharmaceutical composition containing a compound of formula I useful for the treatment of acute or chronic neurodegenerative diseases is claimed.
Patent NZ-333000-A (NZ)
Title: Isoindole and condensed ring pyrrole compounds and pharmaceutical compositions containing them
Inventor: DE NANTEUIL GUILLAUME
IPC: C07D401/04
Filed: 1998-11-25
Abstract: The disclosure provides compounds of formula (I) wherein R represents a hydrogen atom, a linear or branched (C1-C6)-alkyl group optionally substituted with one or more, identical or different groups selected from hydroxy, linear or branched (C1-C6)-alkoxy, carboxy and linear or branched (C1-C6)-alkoxycarbonyl groups, an amino group optionally substituted with one or two, identical or different groups selected from linear or branched (C1-C6)-alkyl, linear or branched (C1-C6)-alkoxycarbonyl, linear or branched aryl-(C1-C6)-alkoxycarbonyl, linear or branched (C1-C6)-alkylsulphonyl and arylsulphonyl, or a linear or branched (C1-C6)-acyl group; R1 & R2 which may be identical or different, each represent independently an aryl, heteroaryl or (C3-C7)-cycloalkyl group, each being optionally substituted as described in the claims; A, together with the atoms in common with the pyrrole moiety, a saturated or unsaturated, monocyclic or bicyclic (C3-C12)-cycloalkyl group (provided that the cycloalkyl group is not aromatic), a saturated heterocycle have from 5 to 7 ring members and containing 1 or 2 nitrogen atoms, or a 7-oxabicyclo[2.2.1]heptane radical, each being optionally substituted as described in the claims.
Patent NZ-333957-A (NZ)
Title: Compounds able to displace tritiated cis-N-cyclohexyl-N-ethyl[3-(3-chloro-4-cyclohexyphenyl)-allyl]amine
Inventor: BRELIERE JEAN-CLAUDE
IPC: C07D211/52
Filed: 1997-07-28
Abstract: The use of compounds (formulae I-VII) capable of displacing tritiated cis-N-cyclohexyl-N-ethyl [3-(3-chloro-4-cyclohexylphenyl)-allyl] amine from its receptors for the preparation of medicaments intended to diseases resulting from cell proliferation. Wherein; Formula (I) R1 represents a hydrogen atom or a halogen atom; R2 represents a cyclohexyl; R3 represents a cycloalkyl containing from 3 to 6 carbon atoms; R4 represents a hydrogen atom, C1-6alkyl or C3-6cycloalkyl; A represents -CO-CH2, -CH(Cl)-CH2, -CH(OH)-CH2, -CH=CH, -CºC-; Formula (II) R1a represents hydrogen or a halogen; R2a is a cyclohexyl group Aa is -CO-CH2, -CH(OH)-CH2, -CH=CH-, -CºC-; Formula  (III) R1b represents a hydrogen atom or a halogen atom; R2b represents a cyclohexyl; R3b represents a hydrogen atom or C1-3alkyl group; R4b represents C1-3alkyl group which may be identical or different to the alkyl group in R3b; R3b and R4b represents considered together may form a 5- or 7-membered heterocyclic group chosen from piperidino, morpholino and pyrrolidino; Ab represents -CH2CH2- or -CH=CH- group; Formula (IV) Ar represents a substituted or unsubstituted phenyl or napthyl; n represents an integer 1-4; RB represents an alkyl group, RB or RC forms a bridge -CH2)p-, -CH= bridge; RA represents a hydroxyl or alkoxy group; RD represents a hydrogen atom; X and Y each represents two hydrogen atoms or RD; Formula (V) Ar2 and Ar3 are identical or different represents a phenyl group, napthyl or phenyl group substituted 1-3 groups; X' and Y' represents two hydrogen atoms or an oxo group; RE represents C1-6alkyl group; Formula (V) R3c is H or C1-3alkyl; R1c and R2c are H, OH, C1-3alkyl, C1-3alkoxy, halogen or cyano; V1 and V2 form a double bond linked to the oxygen atom, a hydroxyimino radical N-OH or ethylenedioxy chain -OCH2CH2O-; Ad represents a valency bond, an oxygen atom, a methylene group or an ethylene; m' is 0 to 2; n' is 1 to 5; Formula (VII) m" and n" is 1 or 2, Cy is CC3-7cycloalkyl; Ar4 is aryl, a heteroaryl; Formula (VIII) L and L' is independently hydrogen and the other is hydrogen, F, Cl or nitro or both L and L' are Cl atom; Z is as disclosed.
Patent NZ-335912-A (NZ)
Title: Implement for milking cows comprising milk units arranged in a carousel and a robot arm for automatic connection of teat cups to a cow
Inventor: VAN DEN BERG KAREL
IPC: A01J5/017
Filed: 1997-07-01
Abstract: An implement comprising milk units 1 and a robot arm construction 3, for the automatic connection of teat cups 25 to the teats of a cow, is claimed.  The milk units are arranged in a carousel.  At least one rail 5 extends in a circle about the carousel, or thereabove, and along which the robot arm construction is movable.
Patent NZ-501606-A (NZ)
Title: Valve and oscillator for producing a pressure waveform
Inventor: HAYEK ZAMIR
IPC: A61H31/02
Filed: 1998-05-06
Abstract: A valve for controlling gas flow to ventilator or physiotherapy apparatus, has a body having first and second inlet ports and an outlet port. A shutter plate is rotatable with respect to said body and adapted selectively to interconnect said inlet ports to said outlet port. Said shutter plate is operable on rotation in a single sense to connect alternately said first inlet port to said outlet port and said second inlet port to said outlet port.
Patent NZ-501768-A (NZ)
Title: Synthetic antibiotics, method for selecting them and use as a fungicide
Inventor: EDWARDS DAVID L
IPC: G01N33/53
Filed: 1998-06-09
Abstract: A method for selecting antibiotic compositions comprising creating a synthetic peptide combinatorial library, contacting a battery of fungal cells with aliquots of the peptide combinatorial library, each of which aliquots represents an equimolar mixture of peptides in which at least two C-terminal amino acid residues are known, measuring the growth of the battery of fungal cells as compared to untreated control cells and determining which of the aliquots most reduces the growth of fungal cells overall in the battery of fungal cells.
Patent NZ-501912-A (NZ)
Title: Synthetic metal-substituted bacteriochlorophyll derivatives and use for killing viruses and microorganisms
Inventor: SCHERZ AVIGDOR
IPC: C07D487/22
Filed: 1996-11-24
Abstract: A process for the preparation of a synthetic metallated bacteriochlorophyll of the formula:  [M]-Bchl  wherein, Bchl represents the residue of a demetallated natural or synthetic bacteriochlorophyll carrying at position 173 an ester group -COOR1 wherein R1 is a C1-C25 hydrocarbyl residue, M represents a metal with an ionic radius smaller than that of Cd (r@95pm), said metal M being selected from the group consisting of a divalent metal selected from the group consisting of pd, Co, Ni, Cu, Zn and Mn, a trivalent metal selected from the group comprising Sn and Pt, which process comprises; (i) reacting a bacteriopheophytin corresponding to said BChl dissolved in dimethyl formamide with dehydrated Cd acetate in Ar atmosphere and recovering the [Cd]-BChl complex from the reaction mixture by chromatography under reducing conditions; (ii) reacting the [Cd]-BChl complex produced in step (i) dissolved in dry acetone with an appropriate dehydrated metal M salt selected from metal M chloride, acetate and acetyl-acetonate in Ar atmosphere; and (iii) recovering the desired metallated [M]-BChl from the reaction mixture. Also described is the use of compounds of formulae I, II and III in the manufacture of medicaments for use in photodynamic therapy, for diagnosis of tumors and for killing cells or infectious agents comprising bacteria and viruses.
Patent NZ-507263-A (NZ)
Title: Coin payout device
Inventor: NAKAJIMA KENJI
IPC: G07D3/14
Filed: 2000-09-29
Abstract: A coin payout device comprises: a) a coin tube for storing stacked coins; b) a payout slide arranged on bottom of the coin tube so as to be capable of moving in a reciprocating fashion and formed with a coin holding hole, for holding, in a coin storage position, a lowermost coin of the coins stacked in the coin tube in the coin holding hole and for paying out the lowermost coin in the coin holding hole by moving the lowermost coin to a coin payout position; and c) a coin support means made of a resilient material and arranged in such a way that one end is pivotably supported on a side wall of the coin tube and another end is positioned in a lowermost part of the coin tube, the coin support means including an engagement portion formed so as to project from a part of the another end and a coin support component for supporting the lowermost coin, the coin support component being formed at another part of the another end so as to be bent into an L shape at an inner side from a tip end of the engagement portion and to project into an opening in the lowermost part of the coin tube; wherein a gap is provided between at least a part of the payout slide and the lowermost part of coin tube, the coin support component of the coin support means being able to move into the gap, whereby when the payout slide is in the coin storage position, the coin payout slide pushes out the engagement portion so that the coin support component is moved away from the bottom opening of the coin tube and when the payout slide is in the coin payout position, the coin support component is made to project into the bottom opening of the coin tube.
Patent NZ-509618-A (NZ)
Title: A patch-in-a-bottle that provides a fluid composition, which is applied to a surface and subsequently dries to form a covering, such as a patch
Inventor: BRANDT PATRICIA J ANDOLINO
IPC: A61K9/70
Filed: 1999-07-20
Abstract: Described is a "patch in a bottle" technology in which a  fluid  composition, e.g., an aerosol  spray,  is  applied onto  a  surface  as  a  fluid, but then  dries  to  form  a covering element, such as a patch, having a tack free  outer surface  covering an underlying adhesive that  helps  adhere the  patch to the substrate.  The fluid compositions have  a unique  chemical  formulation  that  allows  such  composite patches   to   form  in  situ.   Specifically,   the   fluid compositions  include  a  tacky  component,   such   as   an adhesive, and a film-forming, non-tacky component.  The non- tacky  and  tacky components are selected to  be  immiscible with  each  other  so  that  the  components  undergo  phase separation as the fluid composition dries.
Patent NZ-509977-A (NZ)
Title: A two-piece capsule for receiving pharmaceutical preparations for powder inhalers
Inventor: ECKERT JOSEF
IPC: A61K9/72
Filed: 1999-08-03
Abstract: A capsule for pharmaceutical preparations for powder inhalers consisting of a capsule body and a capsule cap, which both consist of the same material and which can be attached to one another so as to form a stable, enclosed hollow space of defined volume, wherein the capsule material is a water-insoluble, hydrophobic synthetic material.
Patent NZ-517404-A (NZ)
Title: Benzopyran derivative
Inventor: TANIKAWA KEIZO
IPC: C07D405/12
Filed: 2000-09-14
Abstract: Benzopyran derivative of formula (I) wherein, R1 and R2 represent each independently a hydrogen atom, a (substituted) C1-6 alkyl group or a (substituted) phenyl group,R3 represents a hydroxyl group or C1-6 alkylcarbonyloxy group, R4 represents a hydrogen atom, or R3 and R4 together form a bond, m represents an integer of 0-4, n represents an integer of 0-4, Y is absent, or represents CR11R12 in which R11 and R12 represent each independently a hydrogen atom or a C1-6 alkyl group, R5 represents an aryl group or a (substituted)heteroaryl group,R6 represents a hydrogen atom or a C1-6 alkyl group,R7 represents a hydrogen atom or a C1-6 alkyl group, X is absent, or represents C=O or SO2, R8 represents a hydrogen atom, a (substituted)C1-6 alkyl group or C3-6  cycloalkyl group, and R9 represents a nitro group, etc., or a pharmaceutically acceptable salt thereof. And this also relates an antiarrhythmic agent having the prolongation effect on the functional refractory period comprising said compound or a pharmaceutically acceptable salt thereof as an active ingredient.
Patent NZ-520377-A (NZ)
Title: New benzo[b]pyrano[3,2-h]acridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: KOCH MICHEL
IPC: C07D491/052
Filed: 2002-07-24
Abstract: Disclosed are compounds of formula (I), for which the substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of cancer.
Patent NZ-520472-A (NZ)
Title: Ruminant MHC class I-like Fc receptors
Inventor: HAMMARSTROM LENNART
IPC: C07K14/705
Filed: 2001-02-02
Abstract: A method of producing colostrums or milk with enhanced levels of immunoglobulins or proteins fused to immunoglobulin g -chains or FcRn interacting parts thereof, comprising the steps of transferring an immunoglobulin G (IgG) transporting ruminant Fc receptor (FcRn) a-chain DNA molecule through transient or persistent transgenesis into the corresponding ruminant animal for overexpression of the protein expressed by the ruminant FcRn a-chain DNA molecule, optionally at concomitant upregulation of the expression of the corresponding b2- microglobulin gene, to increase the number of functional receptors in the udder, thereby enhancing the transport of immunoglobulins and/or proteins fused to immunoglobulin g -chains or FcRn interacting parts thereof from, or through, the udder into the colostrums or milk.
Patent NZ-525087-A (NZ)
Title: Sale method and system employing product price varying dependent upon valid date of product
Inventor: TAK SEUNG-HO
IPC: G06Q10/00
Filed: 2001-09-27
Abstract: A system for determining a product price based on how much time has passed since a product was manufactured comprises: a product code reading means (530) which reads the product information about a predetermined product and time information on when the predetermined product was manufactured by identifying a product code (510) attached to the predetermined product; a storing means which stores different discount rates for each product depending on how much time has passed since its corresponding product was manufactured and a price determining means (520) which calculates an elapsed time, which is the time that has passed since the predetermined product was manufactured based on the manufacturing information and determines the price of the predetermined product using an appropriate discount rate corresponding to the elapsed time from among the discount rates for the predetermined product stored in the storing means. The system can also have a server which transmits the different discount rates for each of the products, depending on how much time has passed since its corresponding product was manufactured, to the price determining means connected thereto over a communication network.