baber/WOPTO huggingface dataset:
Patent CA-2536256-C (CA)
Inventor: BORSI LAURA
IPC: A61K51/10
Filed: 2004-09-01
Granted: 2013-02-26
Abstract: A specific binding member that binds human ED-B, wherein the specific binding member is labelled with an isotope selected from the group consisting of 76Br, 77Br, 123I, 124I, 131I and 211At and comprises an antigen-binding site that comprises an antibody VH domain and an antibody VL domain, wherein the antibody VH domain is selected from the group consisting of the L19 VH domain, and a VH domain comprising a VH CDR1, a VH CDR2 and a VH CDR3, wherein the VH  CDR3 is the L19 VH CDR3 of SEQ ID NO. 3, the VH CDR1 is optionally L19 VH CDR1 of SEQ ID NO. 1, and the VH CDR2 is optionally L19 VH CDR2 of SEQ ID NO. 2;  and wherein the antibody VL domain is optionally selected from the group consisting of the L19 VL domain, and a VL domain comprising a VL CDR1, a VL  CDR2 and a VL CDR3, wherein the VL CDR3 is the L19 VL CDR3 of SEQ ID NO. 6, the VL CDR1 is optionally L19 VL CDR1 of SEQ ID NO. 4, and the VL CDR2 is optionally L19 VL CDR2 of SEQ ID NO. 5; the L19 VH domain and L19 VL domain sequences being disclosed in Pini et al. (1998) J. Biol. Chem. 273: 21769-21776; wherein the specific binding member comprises a mini-immunoglobulin comprising said antibody VH domain and antibody VL domain fused to eS2-CH4 and dimerized or comprises a whole IgG1 antibody molecule; also methods and uses employing such a specific binding member.
Patent CA-2538806-C (CA)
Title: Annular acoustic panel
Inventor: HARRISON GEOFFREY E
IPC: B64D29/00
Filed: 2004-10-14
Granted: 2008-12-09
Abstract: An aircraft engine assembly (10) is provided that is adapted to reduce noise produced by an engine (14) included in the engine assembly. The engine assembly (10) includes a nacelle (26) having an inlet section (34) and a main section (38) that is houses the engine (14) and fan assembly (18) associated with the engine. The inlet section (34) is coupled to the main section (38) at a main bulkhead (42) junction between the inlet section (34) and the main section (38) . A one piece annular acoustic panel (46) is located within a recess in an internal wall (54) of the nacelle (26) . The annular acoustic panel (46) extends from a forward portion of the inlet section (34) to a forward portion of the main section (38) such that the bulkhead (42) is covered by the annular acoustic panel (46).
Patent CA-2539668-C (CA)
Title: Steerable drilling system
Inventor: SMITH DAVID L
IPC: E21B21/10
Filed: 2006-03-14
Granted: 2012-08-14
Abstract: A steerable drilling system comprises a bias unit 10, the bias unit 10 having at least one actuator 14 operable by pressurised drilling fluid or mud, in use, and a separator 20 arranged to remove particulate matter from the supply of pressurised drilling fluid or mud to the or each actuator 14, the separator 20 comprising a hydrocyclone 20.
Patent CA-2548488-C (CA)
Inventor: SMITH R STEWART
IPC: A01N63/20
Filed: 2004-12-23
Granted: 2016-12-13
Abstract: Methods and compositions for enhancing plant characteristics of leguminous and non-leguminous crops include combination treatments with at least one fungicide, insecticide, or combination thereof, and one or more plant inducers, such as nod factors. Optionally, an inoculant composition may be used with the invention to enhance nodulation and nitrogen fixation with legumes.
Patent CA-2550789-C (CA)
Inventor: KRISTENSEN ANNA CECILIE JENTOFT
IPC: C12N9/10
Filed: 2004-12-23
Granted: 2015-02-10
Abstract: The present invention relates to a method of reducing and/or removing diglyceride from an edible oil, comprising a) admixing an edible oil with an acyl acceptor substrate and a fatty-acid CoA independent diglyceride: glycerol acyltransferase, wherein the fatty-acid CoA independent diglyceride: glycerol acyltransferase is characterized as an enzyme which in an edible oil is capable of transferring an acyl group from a diglyceride to glycerol.  Preferably, the diglyceride: glycerol acyltransferase comprises the amino acid sequence motif GDSX, wherein X is one or more of the following amino acid residues L, A, V, I, F, Y, H, Q, T, N, M or S. Furthermore the present invention relates to the use of a fatty-acid CoA independent diglyceride:  glycerol acyltransferase characterized as an enzyme which in an edible oil is capable of transferring an acyl group from a diglyceride to glycerol, in the manufacture of an edible oil, for reducing and/or removing (preferably selectively reducing and/or removing) diglyceride from said edible oil, and to the use of said enzyme in the manufacture of a foodstuff comprising an edible oil for improving the crystallization properties of said foodstuff.
Patent CA-2551493-C (CA)
Inventor: LEVERD ELIE
IPC: A61P35/00
Filed: 2004-12-17
Granted: 2012-12-04
Abstract: The invention relates to a pharmaceutical composition of vinflunine in the form of a stable sterile aqueous solution of a water-soluble salt of vinflunine with a pH of between 3 and 4. The invention also relates to the method of preparing said composition and to the use thereof as a parenterally-administered medicament for the treatment of cancer.
Patent CA-2556632-C (CA)
Title: Egf receptor epitope peptides and uses thereof
Inventor: JOHNS TERRANCE GRANT
IPC: G01N33/566
Filed: 2005-02-18
Granted: 2016-10-11
Abstract: The present invention relates generally to growth factor receptor epitope peptides, particularly EGF family receptor epitope peptides. The invention also relates to the use of the receptor peptides in generating antibodies which have anti-tumor or anti-cancer activity or in stimulating an immunological response. The invention further relates to antibodies specifically directed against the receptor peptides. Methods for generating an immune response and for treatment of tumors and cancer are also provided.
Patent CA-2557157-C (CA)
Title: Bulkhead socket for a co-axial plug and socket connector
Inventor: ROSENBERGER BERND
IPC: H01R13/646
Filed: 2005-05-11
Granted: 2009-09-01
Abstract: The invention relates to a housing coupler (100) for a coaxial plug-in connector, particularly of the N-type, comprising a cylindrical housing (10), which forms an outer conductor and which has a coaxial cable-side end (12) and a plug-side end (14). The arrangement is characterized in that a groove (34) is formed on an inner wall of the housing (10) next to the plug-side end (14) while extending in an annular manner and forming a detent edge (30).
Patent CA-2558602-C (CA)
Title: Forward scanning imaging optical fiber probe
Inventor: YANG CHANGHUEI
IPC: A61B1/07
Filed: 2005-03-22
Granted: 2012-09-11
Abstract: Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as to image a conical scan volume when light is provided by the source. Reflected light from a sample under investigation is collected by the fiber and analyzed by an imaging system.  Such probes may be very compact, e.g., having a diameter 1 mm or less, and are advantageous for use in minimally invasive surgical procedures.
Patent CA-2560753-C (CA)
Inventor: MAKAROV ALEXANDER ALEKSEEVICH
IPC: H01J49/04
Filed: 2005-03-29
Granted: 2013-08-06
Abstract: The present invention relates to a method and apparatus for ion fragmentation by electron capture. The present invention provides a method of generating fragment ions by electron capture, comprising; directing ions to be fragmented into a fragmentation chamber of a mass spectrometer into a fragmentation chamber of a mass spectrometer arrangement; trapping at least some of the ions to be fragmented in at least one direction of the fragmentation chamber by using a magnetic field, the ions being trapped within a volume V; generating an electron beam using an electron source located away from the volume V;  irradiating the trapped ions in the volume V with the electrons generated by the electron source in the presence of the said magnetic field, so as to cause dissociation; and ejecting the resultant fragment ions from the fragmentation chamber for subsequent analysis at a different location away from the fragmentation chamber.
Patent CA-2566481-C (CA)
Inventor: HOCQUAUX MICHEL
IPC: A23L1/305
Filed: 2005-05-10
Granted: 2013-12-03
Abstract: The invention relates to a peptide of formula W-DPhe-Arg- Z (I) and to a conjugate thereof of a formula A-W-DPhe-Arg-Z (II), wherein A is a radical corresponding to a monocarboxylic acid of general formula HOOC-R (III), wherein R is an linear or branched possibly substituted by a hydroxy group aliphatic C1-C24 radical which can comprise one or several unsaturations, preferably from 1 to 6 unsaturations, a lipoic acid or the reduced form thereof, a dihydrolipoic acid, N-lipoyl-lysine or a phenylbutyric acid, W is His, Ala-His, Ala-Ala-His, Nle-Ala-His, DTrp-Ala-His, Nle-Trp-His, Lys, Ala-Lys, Nle-Ala-Lys, Orn, Ala-Orn, Nle-Ala-Orn, Ala, Nle-Ala-Ala, Arg, Ala-Arg, Nle-Ala-Arg, Nle-Ala-DTrp or a bond in case of compounds of formula (II), Z is NH2, OH and OR, wherein R is a linear or branched aliphatic C1-C24 radical, TrpNH2, NapNH2, TpiNH2, TicNH2, AlaNH2i TrpOH, NapOH, TpiOH, TicOH, AlaOH, PheNH2, or PheOH, exempting a peptidic conjugate for which A is a radical corresponding to an acetic acid, W is Nle-Ala-His and Z is TrpNH2 in the form of enantiomers or diastereoisomer and the mixtures thereof including racemic mixtures. The use of the inventive compounds for cosmetically fighting against canities is also disclosed.
Patent CA-2579136-C (CA)
Title: Screen and screen element
Inventor: GROENVALL LARS
IPC: B07B1/46
Filed: 2005-09-09
Granted: 2013-01-22
Abstract: A screen element (2) of a screen (1) has longitudinal sides adapted to be arranged in a longitudinal direction of a screen frame (4) and transverse sides adapted to be arranged in a transverse direction of the screen frame (4) . The transverse sides of the screen element (2) are provided with at least one projection (6) and/or at least one recess (7) for locking engagement, in a direction transversely to the plane of the screen element (2), with a corresponding projection (6) and/or recess (7) on neighbouring screen elements arranged in the screen frame (4) . A screen (1) with a screen element (2) arranged in a screen frame (4) is also disclosed.
Patent CA-2582339-C (CA)
Inventor: OMORI YASUHIRO
IPC: A61P13/08
Filed: 2005-10-04
Granted: 2014-04-22
Abstract: An agent for the prevention and/or treatment of urine collection disorders associated with lower urinary tract obstructive disease, characterized by containing an indoline derivative represented by the following general formula (I): (see formula I) wherein R represents optionally substituted aliphatic acyl optionally having an unsaturated bond, hydroxyalkyl, aliphatic acyloxyalkyl, lower alkoxy, carboxy, lower alkoxycarbonyl, aryl(lower alkoxy)carbonyl, carbamoyl, (mono- or dialkyl)carbonyl or cyano(lower alkyl), optionally halogenated aromatic acyl, furoyl, or pyridylcarbonyl; R1 represents cyano or carbamoyl; and R2 represents lower alkyl optionally having a halogen atom, cyano group, or aryl group, or a pharmaceutically acceptable salt of the derivative. The derivative and salt are usable as an agent for the prevention and/or treatment of urine collection disorders associated with lower urinary tract obstructive disease.
Patent CA-2588081-C (CA)
Title: Method and system to monitor and control devices utilizing wireless media
Inventor: STATON WELTEN HOUSTON
IPC: H04M11/00
Filed: 2005-10-20
Granted: 2016-01-19
Abstract: A method and system of selectively communicating with one or more devices within pre-defined geographical zones is disclosed. A plurality of geographical zones is defined, each zone being defined by latitude and longitude attributes. A plurality of devices is associated with each geographical zone with which a portable device can communicate, the portable device having data representative of the plurality of geographical zones. The portable device also has a ground positioning unit receiver to obtain geographical coordinates of the portable device. If the portable device determines that its location is within one of the plurality of geographical zones, the portable device communicates with the devices in associated with the geographical zone.
Patent CA-2595439-C (CA)
Inventor: KEARNEY PHILIP F III
IPC: H04W88/16
Filed: 2006-01-06
Granted: 2017-05-02
Abstract: Disclosed herein is a system for enhancing the security of wireless networks. In one aspect, a wireless access point that functions as a bridge between two networks is provided. The wireless access point is configured to establish separate associations for itself and each device connected to it. This provides for enhanced security in that each device connected to the wireless access point may be separately authenticated and in that separate encryption tunnels are established for each device connected to the wireless access point.
Patent CA-2601703-C (CA)
Title: Improvements relating to mass spectrometry
Inventor: MAKAROV ALEXANDER ALEKSEEVICH
IPC: G01N27/623
Filed: 2006-03-29
Granted: 2012-05-15
Abstract: This invention relates to a mass spectrometer including a reaction cell and to a method of using such a mass spectrometer. In particular, although not exclusively, this invention relates to a tandem mass spectrometer and to tandem mass spectrometry. The invention provides a method of mass spectrometry using a mass spectrometer having a longitudinal axis, comprising guiding ions to travel along the longitudinal axis of the mass spectrometer in a forwards direction to pass through an intermediate ion store and then to enter a reaction cell, to process the ions within the reaction cell, to eject the processed ions to travel back along the longitudinal axis to enter the intermediate ion store once more, and to eject one or more pulses of the processed ions in an off-axis direction to a mass analyser.
Patent CA-2602028-C (CA)
Inventor: TANHA JAMSHID
IPC: C40B40/10
Filed: 2006-03-24
Granted: 2015-01-13
Abstract: Polypeptides with desirable biophysical properties such as solubility, stability, high expression, monomericity, binding specificity or non-aggregation, including monomeric human VHs and VLs, are identified using a high throughput method for screening polypeptides, comprising the steps of obtaining a phage display library, allowing infection of a bacterial lawn by the library phage, and identifying phage which form larger than average plaques on the bacterial lawn. Sequences of monomeric human VHs and VLs are identified, which may be useful for immunotherapy or as diagnostic agents.  Multimer complexes of human VHs and VLs are also identified. The VHs and VLs identified may be used to create further libraries for identifying additional polypeptides. Further, the VHs and VLs may be subjected to DNA shuffling to select for improved biophysical properties.
Patent CA-2603117-C (CA)
Inventor: PRATT F DALE
IPC: E21B47/18
Filed: 2004-04-06
Granted: 2013-07-02
Abstract: An improved energy efficient intelligent pulser driver used for generating a mud pulse in a MWD (measurement while drilling) application. In the pulser driver, a direct current (DC) powered control circuit activates a three-phase DC brushless reversible rotary electric motor that operates a servo-valve, opening of which causes the operation of a main valve to reduce flow area and cause a pressure spike in the mud column. Closing the servo--valve similarly operates the main valve and increases the flow area causing an end to the pressure spike. The servo-valve is powered both in opening and closing operations by a reversible rotary electric motor, which in combination with the mechanical advantage provided by a ball-screw and threaded rod in a rotary-to-linear motion converter, provides sufficient force to overcome the resistance of the type of dynamic seal required for isolating the actuator's drive components from the ambient mud.
Patent CA-2604908-C (CA)
Inventor: CHRISTY PAUL G
IPC: B01D21/04
Filed: 2006-04-06
Granted: 2013-06-18
Abstract: A method and apparatus is provided for conveying lime slurry, removing and controlling the amount of grit, and feeding lime slurry, wherein the lime slurry moves through a recirculation loop, and wherein gravity removal of grit from the lime slurry takes place. A stilling well is provided, inside or outside the slurry tank, either fixed in cross-sectional area or adjustable, but wherein the cross-sectional area of the stilling tank can be selected or adjusted to alter the flow velocity of slurry therethrough and the residence time of slurry therethrough, as slurry is delivered through the stilling well via a suction line located therein, whereby grit can be separated via gravity from slurry in the slurry tank prior to withdrawal of slurry through the stilling well.
Patent CA-2610957-C (CA)
Inventor: PASTUSEK PAUL E
IPC: E21B12/02
Filed: 2006-06-07
Granted: 2011-04-05
Abstract: L'invention se rapporte à des outils de forage et à des procédés permettant d'échantillonner des données de capteurs se rapportant à l'état de l'outil de forage. Elle concerne en particulier un outil de forage (200) destiné au forage d'une formation souterraine, qui se compose d'un trépan et d'une tige (210). La tige présente en outre un passage traversant couvrant un diamètre interne donné de la tige, conçu pour recevoir un module d'analyse de données. Le module d'analyse de données comprend une pluralité de capteurs (340), une mémoire (330) et un processeur (320). Le processeur est conçu pour exécuter des instructions d'ordinateur afin de permettre la collecte de données des capteurs, par échantillonnage de la pluralité de capteurs, analyse des données des capteurs afin de mettre au point un indice de gravité, comparaison des données des capteurs avec au moins un seuil adaptatif, et modification du mode d'échantillonnage des données en fonction de cette comparaison. L'invention concerne également un procédé consistant à collecter les données des capteurs par échantillonnage d'une pluralité de paramètres physiques associés à l'état de l'outil de forage dans divers modes d'échantillonnage, et par transfert entre les différents modes d'échantillonnage.
Patent CA-2616908-C (CA)
Title: Support jack
Inventor: SEIDEL GUENTER
IPC: B60S9/08
Filed: 2006-07-20
Granted: 2013-12-03
Abstract: A support jack for supporting semitrailers, with a vertically telescopically displaceable supporting device (2) having an outer sleeve (20) and an inner sleeve (10), is described. The spindle nut (30) has first means (31) and second means (35) for positive releasable connection to the sleeves (10, 20).  The first means (31) interact with means (11) of the inner sleeve (10) for fixing the spindle nut (30) in the direction of the longitudinal axis of the support jack. The second means (35) interact with means (21) of the outer sleeve (20) for fixing the spindle nut (30) in the rotation direction of the longitudinal axis. A method of assembling a support jack is also described, in which the spindle nut is connected releasably to the inner sleeve at least by means of one translatory and one rotary joining movement or at least by means of two translatory joining movements.
Patent CA-2618999-C (CA)
Inventor: VOKEY DAVID E
IPC: G01M3/16
Filed: 2008-01-28
Granted: 2009-03-17
Abstract: A defect in a roof membrane is detected by applying a DC voltage between the roof deck and a perimeter conductor and using a detection probe pair to provide a signal indicative of the differences in voltage detected by the pair of probes so as to allow the operator to locate the defect by moving the probes to different locations. The probes are mounted on a rigid common frame such that the probe pair has a fixed separation and the frame includes a handle portion which allows ready manipulation of the frame carrying the probes by the operator. The receiver provides an audible signal emitter to the operator and includes a calibration circuit arranged to automatically maintain, despite changes in voltage applied between the roof deck and the peripheral conductor, a"0" set calibration point so as to indicate at the calibration point when zero difference in voltage is detected.
Patent CA-2621246-C (CA)
Inventor: OYOBE HICHIROSAI
IPC: H02J7/00
Filed: 2006-09-20
Granted: 2011-06-07
Abstract: When it is determined that an electric storage is to be charged from a commercial power source, a controller sets a control target of a voltage VH of a power line to be controlled by a boost converter, based on a voltage Vac of the commercial power source. Specifically, the controller sets the control target of the voltage VH to a level approximately equal to the crest value of voltage Vac. Then, the controller outputs an input permission command to a relay circuit, and controls inverters to execute charging of the electric storage.
Patent CA-2625052-C (CA)
Inventor: SABOE DENNIS
IPC: B01J19/30
Filed: 2008-03-10
Granted: 2018-08-14
Abstract: In one aspect of the invention there is provided a gas scrubbing system for removing contaminants from a flow of fluid, comprising a container having an interior volume, an inlet for receiving the flow of fluid and an outlet for dispensing the stream of fluid, a treatment liquid, a porous medium positioned in the interior volume, between the inlet and outlet, said porous medium providing a high surface area to facilitate chemical interactions between the fluid flow and the treatment liquid and means to apply the treatment liquid onto the porous medium. A contact cell aspect of the porous medium and a method aspect are also provided.
Patent CA-2629311-C (CA)
Inventor: CHAPPELL MARK DONALD
IPC: A61K31/41
Filed: 2006-11-21
Granted: 2014-05-06
Abstract: The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
Patent CA-2632142-C (CA)
Inventor: YAMANAKA SHINYA
IPC: A61P3/10
Filed: 2006-12-06
Granted: 2013-08-06
Abstract: There is provided a nuclear reprogramming factor for a somatic cell, which comprises a gene product of each of the following three kinds of genes: an Oct family gene, a Klf family gene, and a Myc family gene, as a means for inducing reprogramming of a differentiated cell to conveniently and highly reproducibly establish an induced pluripotent stem cell having pluripotency and growth ability similar to those of ES cells without using embryo or ES cell.
Patent CA-2632226-C (CA)
Title: Decorative effect coating compositions and methods of making and applying same
Inventor: NEGRI ROBERT H
IPC: C09D5/29
Filed: 2006-10-14
Granted: 2012-04-10
Abstract: The disclosure is generally related to a coating composition, and more particularly to a decorative effect coating composition capable of producing a multicolored and/or multishaded appearance in a single application. The multicolor effect arises through multiple tinting colorants that are substantially immiscible and which separate into separate layers upon application. The color difference between the two layers should be at least about 0.25 delta E units. Additional decorative effects may be applied through shearing the surface with a putty knife or other instrument while the coating composition is still in the liquid or simi-liquid state.
Patent CA-2633872-C (CA)
Inventor: KEENEY FRANKLIN N
IPC: A01N43/40
Filed: 2006-11-17
Granted: 2014-04-01
Abstract: Triclopyr butoxyethyl ester compositions with a dearomatized aliphatic solvent or a vegetable oil ester as a carrier provide enhanced control of woody vegetation in foliar applications.