baber/WOPTO huggingface dataset:
Patent EA-018298-B1 (EA)
Title: Two-section gas turbine locomotive
Inventor: RUDENKO VLADIMIR FEDOROVICH
IPC: B61C5/00
Filed: 2012-08-17
Abstract: The invention relates to design of locomotives using cryogenic gas fuel, in particular, liquefied natural gas. A gas turbine locomotive consists of two sections, each comprising a frame with a body, an operator cab, and bogies with wheels pairs provided with drive motors. The first section houses a gas turbine engine, a gas equipment assembly with a gas receiver and an automatic control board, an electrical equipment unit with a high-voltage chamber driving traction engines and an auxiliary equipment. The second section of the gas turbine locomotive comprises a front and rear compartments of the body between them a frame esplanade is arranged. The front section accommodates a control cab and the control system equipment, wherein the rear section houses a cryogenic equipment and the high-voltage chamber driving a traction motors of the second section. A removable tank for storing cryogenic fuel, in particular, liquefied natural gas, as big as a standard container, is accommodated in the center of the section on the esplanade. The removable tank is fixed on the esplanade by means of standard container supports, the supports are equipped with special weight measuring device to control the amount of fuel therein. The invention permits to achieve the following technical results: excluding anchoring a gas turbine locomotive to specific sites of natural gas liquefaction due to the use of removable tanks which can be filled in natural gas liquefaction filling stations and transport thereof directly to gas turbine locomotives operation areas; shortening downtime of a locomotive by changing removable tanks; enhancing the accuracy of fuel consumption.
Patent EA-029300-B1 (EA)
Title: Antibody which binds membrane-bound human carcinoembryonic antigen, production and use thereof
Inventor: HOFER THOMAS U
IPC: C07K16/30
Filed: 2012-02-29
Abstract: The application discloses an antibody with a heavy chain variable region comprising CDR1 SEQ ID NO: 1, CDR2 SEQ ID NO: 13 and also CDR3 selected from the group consisting of SEQ ID NO: 217, SEQ ID NO: 218, SEQ ID NO: 220, SEQ ID NO: 221, SEQ ID NO: 222 and SEQ ID NO: 223; a light chain variable region comprising CDR1 SEQ ID NO: 39, CDR2 SEQ ID NO: 49 and also CDR3 SEQ ID NO: 56. Furthermore, it describes an antibody wherein a heavy chain variable region comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 233, SEQ ID NO: 234, SEQ ID NO: 235, SEQ ID NO: 239, SEQ ID NO: 241, SEQ ID NO: 242, SEQ ID NO: 243 and SEQ ID NO: 247, and a light chain variable region comprises an amino acid sequence SEQ ID NO: 209. These antibodies bind membrane-bound human carcinoembryonic antigen (CEA) and have better therapeutic activity. Furthermore, the objects of the present invention are a polynucleotide, a vector, a cell provided for producing these antibodies and also methods of using the same and the use thereof.
Patent EA-029231-B1 (EA)
Title: Spacing point lock device of special track parts on a sleeper
Inventor: BARRESI FRANCESCO
IPC: E01B9/38
Filed: 2013-12-10
Abstract: The invention is related to a device for railway point locking comprising a plate and a structure including a spacing point lock (VCC), the structure being mounted on a sleeper through the plate, wherein the plate provides rigidity in a range of 180 to 200 kN/mm, and the structure has a base that can be fixed on the sleeper through the plate by means of a clamping device that passes through the plate and serves for provision of a definite preload on the plate. The invention is related also to a method for replacement of the plate at the place of the system operation.
Patent EA-030249-B1 (EA)
Title: 2,4-substituted pyrimidinediamines for use in discoid lupus
Inventor: MAGILAVY DANIEL
IPC: A61P17/00
Filed: 2012-03-09
Abstract: The present invention relates to a method of treating discoid lupus erythematosus, comprising topically administering to a subject having discoid lupus erythematosus but not having systemic lupus erythematosus an effective amount of a compound of formula I and/or IIor a pharmaceutically acceptable salt form thereof.
Patent EA-027930-B1 (EA)
Title: Method for producing a polymer layer with concealed polarization images
Inventor: BOBOREKO ALEXANDER GEORGIEVICH
IPC: G02B1/08
Filed: 2015-06-16
Abstract: The invention is related to the field of protection of documents and securities against forgery, in particular, to the field of producing, on a rolled substrate, a polymer layer with concealed polarization images that can be used as protective marks on various documents, securities, currency notes and similar documents and products. The method according to the invention includes the following steps: a solution of a polymer in an organic solvent with addition of abrasive particles is prepared; the polymer solution with abrasive particles is applied to a substrate and dried to produce an optically isotropic polymer layer including abrasive micro-particles; optically anisotropic areas containing symbols and spaces are produced on said polymer layer by a thermomechanical impact; for this purpose, a single-row block of micro-heating elements is set above the polymer layer, a continuous contact is provided between the micro-heating elements and the polymer layer, and a load is applied to the block of micro-heating elements so that the static linear load of the micro-heating elements on the polymer layer is 2-3 N/cm over the entire width of the substrate; the substrate of the micro-heating elements is started to move and simultaneously a voltage pulse train is applied to the micro-heating elements in accordance with a preset program of formation of symbols and spaces, duration of the first pulse being 2-3 times shorter than duration of the next pulse.
Patent EA-028208-B1 (EA)
Title: System for autonomous power supply to railroad freight cars and/or flat wagons from a wheel pair axle
Inventor: BUROV VALERY VALERIEVICH
IPC: B61D43/00
Filed: 2013-10-09
Abstract: The invention is directed to provision of autonomous power supply without drive power limitation, to extending the service life of the drive and the generator bearings, and to higher repairability of the structure. Said technical result is attained by provision of a system comprising an undercar generator mounted on a rigid frame connected to the car frame and/or a flat wagon frame on one side and to a wheel pair axle on the other side, and a drive that links the wheel pair axle to the generator shaft, wherein the drive comprises a double transmission system consisting of a gear transmission and a belt transmission. The gear transmission includes a detachable drive gear and a driven gear, the belt transmission includes a drive pulley and a driven pulley connected with a drive belt. The drive gear is mounted on a hollow divided shaft, the driven gear is provided with a disengaging mechanism and is mounted on an end of an intermediate shaft fixed on a rigid frame, the drive pulley of the belt transmission is mounted on the other end of the intermediate shaft, and the driven pulley is mounted on the generator shaft.
Patent EA-029682-B1 (EA)
Title: Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound
Inventor: DAHMEN PETER
IPC: A01N45/02
Filed: 2012-04-18
Abstract: The present invention relates to active compound combinations, in particular within a fungicide composition comprising (A) an N-cyclopropyl-N-[substituted-benzyl]-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide or a thiocarboxamide compound derivative and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively or eradicatively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and also to the treated seed.
Patent EA-037971-B1 (EA)
Title: Alkyl tin compound
Inventor: MIYAKE NOBUHISA
IPC: C07F7/22
Filed: 2014-09-22
Abstract: The invention relates to an alkyl tin compound chosen from compounds of general formulaorwherein a plurality of R each independently represents a branched alkyl or cyclic group-substituted alkyl group, and a plurality of OR' each independently represents a C2-8 alkoxy group, the branched alkyl group being a C5-18 alkyl group branched at at least one carbon atom of the first to third carbon atoms counting from the tin atom, and the cyclic group-substituted alkyl group being an alkyl group represented by formula (12), (13) or (14)wherein ring A represents a C3-16 alicyclic hydrocarbon group or a C6-16 aromatic hydrocarbon group. The invention also relates to a catalyst composition comprising said alkyl tin compound and to a catalyst based on said alkyl tin compound for a process for producing a carbonic acid ester from carbon dioxide and an alcohol, as well as to a process for producing a carbonic acid ester using said alkyl tin compound.
Patent EA-036902-B1 (EA)
Title: Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors
Inventor: KORMAN ALAN J
IPC: C07K16/28
Filed: 2014-09-18
Abstract: Provided are methods for clinical treatment of tumors (e.g., advanced solid tumors) using an anti-LAG-3 antibody in combination with an anti-PD-1 antibody.
Patent EA-030222-B1 (EA)
Title: MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIa INHIBITORS
Inventor: CORTE JAMES R
IPC: C07D487/08
Filed: 2015-01-30
Abstract: The present invention relates to compounds of Formula (I)or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. The present invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
Patent EA-036757-B1 (EA)
Title: Pharmaceutical compositions for combination therapy
Inventor: PRUZANSKI MARK
IPC: C07J43/00
Filed: 2016-04-06
Abstract: The present invention relates to a pharmaceutical composition comprising a combination of an FXR agonist and at least one additional therapeutic agent that lowers the glucose level in the blood, stimulates insulin secretion, and/or increases insulin sensitivity. The present invention relates to use of the pharmaceutical composition for the treatment or prevention of a FXR mediated disease or condition, such as NAFLD and NASH, a disease or condition related to an elevated level of glucose in the blood, decreased secretion of insulin, and/or decreased insulin sensitivity such as hyperglycemia, diabetes, obesity, and insulin resistance, or for lowering the glucose level in the blood, stimulating insulin secretion, and/or increasing insulin sensitivity.
Patent EA-037221-B1 (EA)
Title: Method and system for energy-efficient control of rolling stock using the adhesion factor in the electrical braking mode
Inventor: ZHEBRAK LEONID MIKHAILOVICH
IPC: B60W40/06
Filed: 2018-02-14
Abstract: The invention relates to a method for energy-efficient control of rolling stock using the adhesion factor in the electrical braking mode. The technical result is minimizing energy consumption for trains and shunting operations, and slide prevention. The method comprises the following steps: obtaining rolling stock specifications including: the adhesion factor for the electrical braking mode, a priori vector of the relationship between the adhesion factor for the electrical braking mode and speed, the speed, rolling stock weight, electrical braking force, slide presence indicator, route data (including the initial point and destination point), track layout and profile; calculating the adhesion factor for the electrical braking mode based on the data obtained; checking the accuracy of the adhesion factor for the electrical braking mode; developing an optimal control plan for the remaining portion of the route using the rolling stock specifications and the adhesion factor for the electrical braking mode; implementation of the optimal control using the developed optimal control plan.
Patent EA-039884-B1 (EA)
Title: Method for producing emulsion cosmetic concentrate of water/oil type from sea buckthorn fruits
Inventor: TAGIEV SARKHOSH ABULFAZ OGLY
IPC: A61K47/44
Filed: 2020-01-07
Abstract: The invention relates to perfumery and cosmetic industry, in particular, to a technology for producing cosmetic cream concentrates based on natural, biologically active components contained in sea buckthorn fruits, specifically, for producing emulsion creams of oil/water types. The objective of this invention is to create a method for producing cream concentrates from sea buckthorn fruit with a smaller number of technological steps and shorter time spent on their performance, using an economically beneficial raw materials. The method of producing cosmetic cream concentrate of sea buckthorn is as follows. At the first stage, the fruits of sea buckthorn are cleaned, washed to remove impurities and passed through a juicer to get juice. The obtained juice is filtered. To prepare emulsions from the juice, 400 ml of juice is placed into a beaker of 2 l by volume, 800 ml of refined olive oil is added and, while stirring continuously, the temperature of the mass is brought to 80C. After that, 130-133 g of emulsifier T-2 is added to the mass and stirred until the emulsifier is completely dissolved in the system (10-15 min). The mixing process is carried out until the mass reaches room temperature. Thereby, as a result of emulsification, an emulsion concentrate of the water/oil type is produced. The resulting emulsion has a yellowish-gray color and smells of sea buckthorn fruits.
Patent ES-2180395-B1 (ES)
Title: Tapon-grifo para garrafas y similares.
Inventor: OCHOA LABURU ALBERTO
IPC: B65D47/24
Filed: 2000-10-30
Granted: 2004-04-01
Abstract: Tapón-grifo para garrafas y similares. El tapón es aplicable a cuellos o golletes de envases tipo botella o bidón de plástico, comprendiendo un vertedor (1) y un cuerpo de tapón (4) propiamente dicho, en donde el vertedor (1) se acopla a presión sobre la parte interna del gollete (2) del envase y presenta una prolongación superior (5-6) dotada de un resalte (7) complementario de otro resalte (8) previsto en la parte superior de ese gollete (2) del envase, para determinar un medio de anclaje mutuo entre vertedor (1) y gollete (2) para impedir el desacoplamiento involuntario del citado vertedor (1). El cuerpo del tapón (4), además de la torre de vertido convencional (14), se complementa con una tapa (9) vinculada al mismo a través de un abisagramiento (10), tapa (9) que está dotada de un obturador formado por un cuello concéntrico e interno (11) dotado de un resalte (12) complementario de otro resalte (13) previsto en la torre de vertido (14), para constituir un medio de obturación entre ambas partes en la posición de cierre para la tapa (9).
Patent ES-2173806-B1 (ES)
Title: Dispositivo para evitar el golpe de ariete en instalaciones de bombeo de agua
Inventor: IBANEZ GARCIA EDUARDO
IPC: F16L55/045
Filed: 2000-11-28
Granted: 2003-10-16
Abstract: Dispositivo para evitar el golpe de ariete en instalaciones de bombeo de agua cuyo dispositivo se constituye de una placa dotada de perforaciones para el alojamiento de válvulas coplanares que efectúan el cierre y eliminan el golpe de ariete que crea la fuerza viva que se origina en el retroceso de la columna de agua y cuya placa queda retenida entre dos cuerpos tubulares relacionados con bridas, mientras que en los extremos los dos cuerpos presentan bridas de fijación del dispositivo de conducción de agua encontrándose dichos cuerpos relacionados por una conducción lateral regulada con una llave o válvula de paso, y cuya conducción sirve para el vaciado de la tubería de impulsión y cebado de la bomba o bombas correspondientes.
Patent ES-2172461-B1 (ES)
Title: Nuevos ligandos de gd (iii) con estructuras bi-y bis-azolica.
Inventor: BALLESTEROS GARCIA PALOMA
IPC: C07D231/12
Filed: 2001-01-25
Granted: 2003-09-16
Abstract: 1. Un compuesto de Fórmula General A **Figura01** donde los radicales R{sub,1}, R{sub,2}, R{sub,3} y R{sub,4}, tienen los valores conocidos universalmente en la formulación de la química orgánica; que se puede emplear para la preparación de quelatos útiles como agentes de contraste en el diagnóstico por imagen. 2. El compuesto de la Reivindicación 1, en donde X en la Fórmula A es (CH{sub,2}){sub,n}. 3. El compuesto de la Reivindicación 2, en donde n es 0. 4. El compuesto de la Reivindicación 2, en donde n es 1. 5. El compuesto de la Reivindicación 1, en donde X en la Fórmula A es CH{sub,2}OCH{sub,2}. 6. El compuesto de la Reivindicación 1, en donde X en la Fórmula A es CH{sub,2}NHCH{sub,2}. 7. Un procedimiento para la obtención del compuesto de Fórmula general A, de la Reivindicación 1, que se caracteriza porque se hace reaccionar un biazol con 1,2- dibromoetano en presencia de BTBA e hidróxido de sodio, para obtener su correspondiente derivado alquilado, que posteriormente se hace reaccionar con iminodiacetato de metilo, sintetizando el correspondiente derivado metilado que a su vez reacciona con hidróxido sódico en presencia de agua, para conseguir la sal sódica deseada. 8. Un procedimiento para la obtención del compuesto de Fórmula general A, de la Reivindicación 1, que se caracteriza porque se hace reaccionar dos moléculas de 1- cloroetil-3,5-dimetilprazol con paraformaldehido en medio ácido calentándose a continuación la mezcla de reacción, en presencia de ácido clorhídrico, para obtener el correspondiente bispirazol, el cual, a su vez, se hace reaccionar con iminodiacetato de metilo para obtener el correspondiente compuesto intermediario metilado, cuya hidrólisis en medio básico da la sal sódica deseada. 9. Los complejos de los compuestos de la Reivindicación 1 con metales de transición y lantánidos. 10. Los complejos de la Reivindicación 9, en donde el metal a complejar es el Gadolinio. 11. Los complejos de la Reivindicación 9, en donde el metal a complejar es el Disprosio. 12. La utilización clínica, de los compuestos de la Reivindicación 1 y sus correspondientes complejos, en el diagnóstico por imagen.
Patent ES-2255336-B1 (ES)
Title: Sistema de puertas pivotantes correderas.
Inventor: ARGUINENA URRUTIA LUIS JESUS
IPC: E06B3/48
Filed: 2002-11-12
Granted: 2007-04-16
Abstract: Sistema de puertas pivotantes correderas, según el cual las puertas (1) de aplicación se disponen en montaje guiado respecto de un carril superior (2) y un carril inferior (3), mediante respectivas sujeciones (4 y 5) provistas con bisagras para el montaje pivotante de la puerta (1) correspondiente, comprendiendo la sujeción superior (4) un carro que establece montaje guiado de rodadura en apoyo vertical y horizontal respecto del carril (2), mientras que la sujeción inferior (5) establece un encaje de conducción por rodadura mediante inserción vertical respecto del carril (3).
Patent ES-2226566-B1 (ES)
Title: Sistema de limpieza de filtros electrostaticos.
Inventor: HERNANDO ALCAIN JESUS
IPC: B03C3/80
Filed: 2003-06-02
Granted: 2006-04-01
Abstract: Sistema de limpieza de filtros electrostáticos, constituidos por una o más baterías (1, 2 y 3) de electrodos planos. El sistema incluye la inyección en el filtro de aire a presión, en forma de chorros dirigidos hacia los electrodos (4-5). El aire inyectado se distribuye a través de conducciones (10) que discurren próximas y paralelas a los electrodos (4 y 5) y disponen de difusores o boquillas (11) de salida, dirigidos hacia dichos electrodos.
Patent ES-2294869-B1 (ES)
Title: Perfeccionamientos en la fabricacion y montaje de paneles aislantes para cubiertas y fachadas.
Inventor: USON SOBREVIELA FRANCISCO JAV
IPC: B32B37/00
Filed: 2004-03-17
Granted: 2009-02-01
Abstract: Perfeccionamientos en la fabricación y montaje de paneles aislantes para cubiertas y fachadas, de utilidad para el cubrimiento y aislamiento de cubiertas, fachadas y cerramientos de construcciones en general, estando basado en unas chapas metálicas perfiladas en frío entre las que queda dispuesto un material aislante, basándose los perfeccionamientos en el procedimiento de fabricación de paneles de cubierta (1) y fachada (2) aislantes, en posibilitar una aplicación alterna del pegamento sobre la pareja de chapas (3) metálicas, una alimentación de sucesivas placas (7) unitarias de lana de roca y una aplicación de calor en un horno (8) en el proceso de pegado y secado de las placas (7) de lana de roca a la pareja de chapas (3) metálicas entre las que quedan dispuestas, disponiendo el montaje de los paneles de cubierta (1) y fachada (2) aislantes de unos medios de ocultación de la tornillería de anclaje.
Patent ES-2254003-B1 (ES)
Title: Estacion de lijado para una lijadora de banda.
Inventor: WEBER GEORG
IPC: B24B21/06
Filed: 2004-08-20
Granted: 2007-07-16
Abstract: En una estación de lijado para una lijadora de banda, con por lo menos una banda abrasiva continua (14) conducida sobre rodillos de reenvío (16) y una banda de láminas de presión (18) que discurre por el interior de aquélla, para apretar la banda abrasiva (14) contra la pieza (12), la dirección de avance de la banda de láminas de presión (18) está orientada transversalmente respecto a la dirección de avance de la banda abrasiva (14).
Patent ES-2289927-B1 (ES)
Title: Sustrato enzimatico que comprende un compuesto indoxilico y una fuente de plata.
Inventor: COSTA GARCIA AGUSTIN
IPC: C07D209/36
Filed: 2006-05-17
Granted: 2008-12-16
Abstract: Sustrato enzimático que comprende un compuesto indoxílico y una fuente de plata. Sustrato enzimático basado en la combinación de un compuesto indoxílico y una fuente de plata para su uso en la determinación de actividad enzimática. Este sustrato está dirigido a la sensibilización de ensayos enzimáticos, donde el propio enzima sea el analito de interés o donde la actividad enzimática esté relacionada con la concentración del analito de interés. El enzima actúa inicialmente sobre el compuesto indoxílico generando una nueva especie (indoxilo) que se oxida y dimeriza para formar una molécula de la familia del índigo, en este paso de reacción la oxidación va acompañada de una reducción de iones plata (Ag+) a plata metálica (Ago). El uso de la disolución de plata acelera la formación del producto de la familia del índigo. La formación simultánea de dos productos insolubles, uno de la familia del índigo y otro la plata metálica, es especialmente útil en la sensibilización de ensayos histoquímicos,inmunoensayos y ensayos de hibridación de hebras de ADN.
Patent ES-2349224-B1 (ES)
Title: Sistema de monitorizacion para cama hospitalaria.
Inventor: MORENO FUENTES JOSE MANUEL
IPC: A61B5/00
Filed: 2008-02-05
Granted: 2011-11-11
Abstract: Sistema de monitorización para cama
hospitalaria, del tipo de los que comprenden un mueble distribuidor
(1) en la cabecera de la cama hospitalaria de un paciente,
encontrándose en el interior de dicho mueble distribuidor (1) un
concentrador (2) con múltiples conexiones de comunicación serie (5),
las cuales están empotradas en la superficie de dicho mueble
distribuidor (1), y asociado al concentrador (2) al menos un
dispositivo de comunicación inalámbrica local y un dispositivo de
red Ethernet (6) para la conexión de los dispositivos sensores (3)
de constantes vitales del paciente monitorizado, encontrándose dicho
concentrador (2) también asociado a un dispositivo de comunicación
global a distancia, ya sea inalámbrico o por cable. El sistema
comprende unos medios de intercomunicación por vídeo y/o audio
asociados al concentrador (2). El concentrador (2) comprende una
memoria de (13) registro programable de una identificación del
paciente.