baber/WOPTO huggingface dataset:
Patent CA-3126574-A1 (CA)
Title: Cd44 targeted multi-arm conjugate
Inventor: YUAN JIANDONG
IPC: A61K47/64
Filed: 2020-02-17
Abstract: Disclosed is a class of multi-branched drug conjugates capable of specifically targeting CD44. The class of compounds specifically binds to CD44, and may target tumor cells and tissues having high expression of CD44, so that the concentration of the conjugate in a target tissue is high, the clinical treatment effect thereof is improved, and toxicity is reduced. The compound of the present invention is suitable for treating all tumors having high expression of CD44, comprising but not limited to gastric cancer, pancreatic cancer, small cell lung cancer, colon cancer, breast cancer, lung adenocarcinoma, liver cancer, nasopharyngeal carcinoma, malignant glioma, lymphoma, renal carcinoma, ovarian cancer, head and neck cancer, squamous cell carcinoma, and the like.
Patent CA-3128682-A1 (CA)
Title: Oil filter assembly
Inventor: KELLY ANDREW SETZ
IPC: F01M11/03
Filed: 2021-08-20
Abstract: A cast metallic adaptor for a filtering and cooling assembly that eliminates the needs for inserts or plugs and provides for direct threading of associated components to the adaptor. This construction also provides an enclosed flow path with a common axis for improved durability against burst pressure, heat and age degradation, and conditions related to cycling.
Patent CA-3128690-A1 (CA)
Inventor: CIRTWILL JOSEPH
IPC: F02C7/22
Filed: 2021-08-20
Abstract: A method of purging fuel injectors of a gas turbine engine, the fuel injectors fluidly connected to a fuel manifold and having primary and secondary fuel passages fluidly connectable to the fuel manifold, the method includes: selectively fluidly disconnecting one or more of the primary and secondary fuel passages from the fuel manifold; and purging the one or more of the primary and secondary fuel passages by injecting a purging fluid into the one or more of the primary and secondary fuel passages while bypassing the fuel manifold. A fuel injector having two fuel passages, a flow divider valve, and a purging valve is disclosed.
Patent CA-3129229-A1 (CA)
Title: Chimeric cytokine receptors
Inventor: JENSEN MICHAEL C
IPC: C12N15/86
Filed: 2020-02-06
Abstract: Some embodiments of the methods and compositions provided herein relate to chimeric cytokine receptors. In some embodiments, a chimeric cytokine receptor can include an IL-7 tethered to an extracellular IL-7 receptor domain, and an intracellular IL-21 receptor domain linked to the extracellular IL-7 receptor domain. In some embodiments, a T cell containing a chimeric cytokine receptor can be readily activated and/or expanded in the absence of an exogenous cytokine.
Patent CA-3134628-A1 (CA)
Inventor: VOERMAN PAUL
IPC: A24F40/40
Filed: 2020-03-25
Abstract: An electronic cigarette (1) is provided with a power supply portion 3 having a heater (25) and a replaceable cartridge having a liquid store (9). The power supply portion (3) has a fluid transfer element (19, 21) with an elongated shape comprising a first wicking part (21) extending outwardly from the power supply portion (3) as a free end, and a second wicking part (19) configured to deliver liquid to the heater (25) for vaporization. The power supply portion (3) has a seating configured to fixedly attach to the second wicking part (19). The first wicking (part 21) is configured to extend into the liquid store 9 when the power supply portion (3) is connected to the cartridge (5). The replaceable cartridge (5) is removably coupled to the power supply portion (3) such that the first wicking part (21) can be engaged and disengaged from the liquid store (9) and, when disengaged, the fluid transfer element (19,21) is a part of the power supply portion (3).
Patent CA-3136056-A1 (CA)
Inventor: SUDRY YAKIR
IPC: G06F30/15
Filed: 2020-04-02
Abstract: A method for generating a flow model that represents a building plan for constructing a building site, the method comprising: acquire assignment parameters for each of a plurality of objects represented in a building information model (BIM) of the building site; for each of the plurality of objects, assigning the object to one or more of a plurality of construction action elements (CAEs) that represents a construction task based on the assignment parameters of the object; and arranging the plurality of CAEs in an ordered sequence to a generate the flow model. A method for discerning progress of a building project for a building site, based on at least one image captured at the building site associated with the flow model.
Patent CA-3138678-A1 (CA)
Title: Communication devices and systems
Inventor: APRO ATTILA
IPC: H04B1/40
Filed: 2019-05-01
Abstract: An adaptive radio frequency module including a switching circuit to switch receipt of a voltage, an assembly including the adaptive RF module, a system comprising a base unit with one or more radio frequency modules, and a method of operation of the system are provide.
Patent CA-3144315-A1 (CA)
Title: System and method for automated detection of clinical outcome measures
Inventor: ARMITAGE OLIVER
IPC: G16H50/30
Filed: 2020-06-26
Abstract: Systems, apparatus, and method(s) are provided for automatically detecting and/or estimating one or more clinical biomarker(s) of a subject. Sensor data is received from one or more sensor(s) associated with the subject. The sensor data is processed using a first set of machine learning (ML) model(s) configured to extract portions of sensor data relevant for estimating one or more clinical biomarker(s) of the subject. The extracted portions of sensor data from sensors associated with the subject are processed to determine one or more clinical biomarkers. The processing of the received extracted portions of sensor data includes using a second set of ML model(s) configured to estimate the one or more clinical biomarker(s) of the subject. The portions of sensor data may comprise the first set of ML model(s) being configured to extract segments of sensor data and classify the segments of sensor data based on one or more clinical biomarker components for use in the estimation of one or more clinical biomarkers of interest. The second set of ML model(s) are configured to estimate the one or more clinical biomarker(s) of the subject based on the extracted and classified segments of sensor data.
Patent CA-3145750-A1 (CA)
Title: Agent de durcissement et procede
Inventor: AMSTUTZ AARON KENNETH
IPC: B32B5/02
Filed: 2020-07-01
Abstract: La présente invention se rapporte à un matériau thermodurci contenant des esters de ^-hydroxy, ledit matériau thermodurci étant soumis à un processus mécano-chimique pour régénérer un époxyde et une fonctionnalité d'acide carboxylique. Un agent de durcissement pour des huiles végétales époxydées et du caoutchouc naturel époxydé est créé à partir de la réaction entre un acide polyfonctionnel d'origine naturelle et une huile végétale époxydée. L'agent de durcissement peut être utilisé pour produire des résines moulables exemptes de porosité et vulcaniser des formulations de caoutchouc à base de caoutchouc naturel époxydé. Les matériaux fabriqués à partir des matériaux décrits peuvent être avantageusement utilisés en tant que substituts de cuir.
Patent CA-3146204-A1 (CA)
Inventor: ROSA JOSE GUILLERMO
IPC: A61Q19/02
Filed: 2020-06-23
Abstract: Topical cosmetic compositions containing a 4-substituted resorcinol derivative along with N-acetyl methionine exhibit improved storage stability and oxidative stability. A method of stabilizing 4-ethyl resorcinol or 4-hexyl resorcinol in a composition comprising a cosmetically acceptable vehicle by adding to the composition Acetyl Methionine in an amount sufficient to stabilize said 4-ethyl resorcinol or 4-hexyl resorcinol. Use of the N-Acetyl Methionine and stabilized 4-substituted resorcinol derivatives in the manufacture of a topical cosmetic composition.
Patent CA-3146961-A1 (CA)
Title: Apparatus for controlling parking in a parking stall
Inventor: NARDIN ALBERTO
IPC: H04N7/18
Filed: 2022-01-28
Abstract: An apparatus is provided for controlling parking in a parking stall including a camera to take images of a vehicle entering the parking stall, a proximity or ultrasonic sensor arranged to detect entry of the vehicle into the parking stall and a device for broadcasting an audible message to the driver. The device communicates with a web site associated with a plurality of stalls each having an associated control apparatus where the web site contains and provides data to a customer relating to any one or more of the associated stalls where authorized use can be purchased.
Patent CA-3149568-A1 (CA)
Title: Uav airways systems and apparatus
Inventor: SYRACUSE STEVEN J
IPC: H02J7/00
Filed: 2020-08-26
Abstract: UAV airways system generally are disclosed. Such UAV airway systems may comprise UAV cargo transportation systems and UAV surveillance and monitoring systems. Such systems preferably overlay and are commensurate with a system of high-voltage power transmission lines of high-voltage transmission system, and electric field actuated (EFA) generators preferably are utilized in UAVs that travel along the transmission lines, in UAV charging stations located along the transmission lines, or in both. Each EFA generator represents a power supply and comprises first and second electrodes separated and electrically insulated from each other for enabling a differential in voltage at the first and second electrodes resulting from a differential in electric field strength experienced by the first and second electrodes arising from the power transmission lines of the high-voltage transmission system.
Patent CA-3155039-A1 (CA)
Title: Systeme de stockage cryogenique avec capteurs pour mesurer un ou plusieurs parametres a l'interieur de celui-ci
Inventor: GUPTA AMIT
IPC: A01N1/02
Filed: 2020-10-28
Abstract: Un système pour stocker des récipients d'échantillon dans un environnement à température régulée comprend au moins un premier capteur de température positionné pour détecter une température dans une première région de l'environnement à température régulée à l'intérieur du réservoir de stockage cryogénique et au moins un premier capteur de niveau positionné pour détecter un niveau d'un milieu cryogénique dans l'environnement à température régulée à l'intérieur du réservoir de stockage cryogénique. Un procédé de stockage de récipients d'échantillon dans un environnement à température régulée comprend la surveillance d'un ou plusieurs paramètres à l'intérieur de l'environnement à température régulée pour empêcher l'exposition d'échantillons biologiques dans les récipients d'échantillon à des paramètres qui mettent en danger la viabilité des échantillons biologiques.
Patent CA-3155830-A1 (CA)
Title: Sprial deployed isolation tool
Inventor: ZHENG WEI
IPC: E21B33/129
Filed: 2022-04-20
Abstract: A spiral deployed isolation tool includes a central pipe having an outer surface in a conical shape and an axial through hole, and an anchoring sealing structure. The anchoring sealing structure is matched and sleeved on the outer surface of the central pipe. The anchoring sealing structure has a first sealing section and an anchoring section. The first sealing section is located at a larger end of the central pipe. The anchoring section includes a plurality of slips, the first sealing section includes a plurality of first spiral sealing rings. The plurality of slips correspond to the plurality of first spiral sealing rings one by one to respectively form an integal structure. The plurality of slips are uniformly expanded in a radial direction, thereby achieving uniform circumferential distribution of slips, so that the slips are evenly anchored on an inner wall of the whole wellbore.
Patent CA-3155854-A1 (CA)
Inventor: MALYSHEVA VALERIYA
IPC: C12Q1/68
Filed: 2020-10-05
Abstract: La présente invention concerne un procédé d'identification de segments d'acide nucléique interagissant avec un segment d'acide nucléique cible ou des segments ainsi que des kits pour la mise en uvre du procédé. L'invention concerne également un procédé d'identification d'un ou de plusieurs segments d'acide nucléique d'interaction qui indiquent un état pathologique particulier.
Patent CA-3155944-A1 (CA)
Inventor: BERNATCHEZ GABRIEL
IPC: B62D55/07
Filed: 2022-04-13
Abstract: A method of transitioning an electric snowmobile from a drive state to a reverse state comprising receiving at a controller a reverse request from a user interface of the electric snowmobile. Upon receipt of the reverse request, the controller transitions the electric snowmobile from a drive state to a reverse state when a speed signal associated with the electric snowmobile is below a predetermined speed threshold and transitions the electric snowmobile from a drive state to a reverse requested state when a speed signal associated with the electric snowmobile is above a predetermined speed threshold. In the reverse state, the controller drives the electric snowmobile in a reverse direction based on a throttle signal and in the reverse requested state, the controller does not drive operation of the electric snowmobile based on the throttle signal.
Patent CA-3157096-A1 (CA)
Inventor: LIU KAISHEN
IPC: E21B43/267
Filed: 2021-04-02
Abstract: The present application relates to a fracturing system, a control system of the fracturing system and a method for controlling the fracturing system in wellsite operation, wherein, the control system comprises: a fracturing control device configured to acquire a target fracturing pressure of a fracturing unit, perform closed-loop control on the fracturing unit by taking the target fracturing pressure as a control target, and set a target sand blending pressure for the sand blending unit; a sand blending control device configured to perform closed-loop control on the sand blending unit by taking the target sand blending pressure as a control target.
Patent CA-3158521-A1 (CA)
Title: Crystalline forms of c-c chemokine receptor type 4 antagonist and uses thereof
Inventor: ARNOLD DAVID J
IPC: A61K31/4985
Filed: 2020-11-13
Abstract: Crystalline forms of a C-C chemokine receptor type 4 (CCR4) antagonist, oral dosage forms of same and methods of using and preparing same, are provided.
Patent CA-3160201-A1 (CA)
Title: Compositions particulaires de tissu placentaire et methodes d'utilisation
Inventor: PAVESIO ALESSANDRA
IPC: A61K35/50
Filed: 2020-11-13
Abstract: L'invention concerne des compositions contenant des particules de tissu placentaire déshydratées, des méthodes de fabrication des compositions et des méthodes de traitement de divers troubles musculo-squelettiques et d'autres affections à l'aide de telles compositions, y compris l'arthrose (OA), la discopathie dégénérative, la tendinite, la fasciite plantaire et la douleur associée à celle-ci.
Patent CA-3162734-A1 (CA)
Title: End effector for gripping and spinning pipes
Inventor: LINDBLOM ANDREAS JOHAN
IPC: E21B19/16
Filed: 2022-06-15
Abstract: There is disclosed an end effector for gripping and spinning a pipe, the end effector com-prising: - a head portion including a first connection interface for connecting the end effector to a robotic arm, - a pair of jaws rotatably connected to the head portion between an open position and a gripping position; - a spinner for spinning a pipe held by the pair of jaws in the gripping position around a spinning axis generally corresponding to a longitudinal centre axis of the pipe, wherein the first connection interface has a normal which is substantially parallel to the spinning axis. There is also disclosed a robot including an end effector as well a robot assembly and a drilling installation including such as robot.
Patent CA-3165479-A1 (CA)
Title: Combinations
Inventor: SAMATAR AHMED ABDI
IPC: A61K31/437
Filed: 2020-12-16
Abstract: Disclosed herein are combinations of compounds for treating a disease or condition, such as cancer. A combination of compounds for treating a disease or condition can include a SERD inhibitor and a WEE1 inhibitor, along with pharmaceutically acceptable salts of any of the foregoing.
Patent CA-3166666-A1 (CA)
Title: Systems and methods for normalizing and aggregating point balances to a common basis
Inventor: HENNESSY MATTHEW
IPC: G06Q30/0226
Filed: 2022-06-30
Abstract: An example system includes an e-commerce platform to support e-commerce for a plurality of merchants; a loyalty rewards system to; track, for each merchant, customer accounts and associated loyalty rewards points for each respective customer account; a hub system to: track, for a hub account, a set of associated customer accounts, each associated customer account corresponding to one of the merchants; retrieve the associated loyalty rewards points for each respective customer account in the set of associated customer accounts; select a common basis; convert, for each respective customer account in the set, the associated loyalty rewards points to a nominal value in the common basis for each respective customer account; aggregate the nominal values of the respective customer accounts in the set; and output the aggregated nominal values to a client device associated with the hub account,
Patent CA-3167205-A1 (CA)
Title: Human milk oligosaccharides to promote growth of beneficial bacteria
Inventor: BUCK RACHAEL
IPC: A23L33/00
Filed: 2011-12-22
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, and children for improving gastrointestinal function and tolerance, as well as the growth of beneficial bacteria. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed.
Patent CA-3169018-A1 (CA)
Inventor: DLUBAK CHARLOTTE
IPC: A61K38/16
Filed: 2021-02-26
Abstract: L'invention concerne une composition comprenant des protéines de légumineuses texturées par voie sèche, son procédé de production ainsi que son utilisation.
Patent CA-3170965-A1 (CA)
Inventor: Shi xiao qi
IPC: G06N3/04
Filed: 2022-08-23
Abstract: Systems, devices, and methods for automated generation of resource task requests are disclosed. A reinforcement learning neural network having an output layer with a plurality of policy heads is maintained. At least one reward is provided to the reinforcement learning neural network, the at least one reward corresponding to at least one prior resource task request generated based on outputs of the reinforcement learning neural network. State data are provided to the reinforcement learning neural network, the state data reflective of a current state of an environment in which resource task requests are made. A plurality of outputs is obtained, each from a corresponding policy head, the plurality of outputs including a first output defining a quantity of a resource and a second output defining a cost of the resource. A resource task request signal is generated based on the plurality of outputs from the plurality of policy heads. _ =
Patent CA-3176623-A1 (CA)
Inventor: TAFUNI DOMENICO
IPC: F15C3/02
Filed: 2022-09-27
Abstract: A valve (200) for controlling the flow of hydraulic fluid to a hydraulic motor (214) is disclosed. The valve (200) includes a sleeve (209) and a spool (212). The sleeve (209) includes a first fluid flow port (201) for receiving hydraulic fluid from the supply line (223); a second fluid flow port (202) for supplying hydraulic fluid to a second valve (213); a third fluid flow port (203) for receiving hydraulic fluid from a first control line (220a); a fourth fluid flow port (204) for receiving hydraulic fluid from a second control line (220b); and a fifth fluid flow port (205) in fluid communication with the return line (224). The valve (200) is arranged to be actuated to move the spool (212) between a first position and a second position. When the spool (212) is in the second position, the fifth fluid flow port (205) is in fluid communication with the second, third and fourth fluid flow ports (202, 203, 204) and the first fluid flow port (201) is closed by the spool (212).
Patent CA-3176938-A1 (CA)
Inventor: CUNE CASTELLANA JORDI
IPC: C12N1/20
Filed: 2014-08-07
Abstract: The invention provides a Bifidobacterium longum strain deposited in the Spanish Type Culture Collection under the accession number CECT 7894, said strain is useful in the amelioration of excessive crying in infants. A bacterial composition comprising this Bifidobacterium longum strain and a pharmaceutically acceptable carrier can be in the form of a food supplement, a medicament, an infant formula, an edible product or a food product. Particularly, the composition is in the form of an infant food supplement in the form of oily suspension.
Patent CA-3178415-A1 (CA)
Title: Salt and crystal forms of 4-amino-5-(6-(4-methylpiperazin-1-yl)-1h-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7h)-one
Inventor: BRAY MARK R
IPC: C07D495/04
Filed: 2021-05-10
Abstract: A novel salt form of Compound (I) represented by the following structural formula, and its corresponding pharmaceutical compositions, are disclosed. (I), Particular single crystalline forms of 1:1 Compound (I) tartrate salt are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms are also disclosed. The present disclosure also provides methods of treating cancer in a subject.
Patent CA-3182173-A1 (CA)
Inventor: SCHEUERELL ALEX R
IPC: B60G7/00
Filed: 2022-11-21
Abstract: A utility vehicle includes a rear suspension assembly which has a trailing arm generally extending longitudinally. The trailing arm includes a joint along a longitudinal length of the trailing arm. Also, the rear suspension assembly includes an upper radius rod extending in a generally lateral direction relative to a centerline of the vehicle.  Additionally, the rear suspension assembly includes a lower radius rod extending in a generally lateral direction relative to the centerline of the vehicle. The rear suspension assembly further includes a suspension member configured to control toe of the at least one rear ground-engaging member.
Patent CA-3182443-A1 (CA)
Inventor: IVARSSON LARS
IPC: E05B77/44
Filed: 2021-06-14
Abstract: L'invention concerne un dispositif de verrouillage destiné à verrouiller une roue d'un véhicule, comprenant un module principal apte à être fixé à une jante de la roue et conçu pour recouvrir des écrous ou des boulons qui fixent la roue au véhicule, un boulon central tubulaire ayant une surface externe filetée et conçu pour adapter un cylindre de verrouillage, le boulon central tubulaire étant en outre apte à être relié au module principal par l'intermédiaire d'un manchon d'insert ; et au moins un élément fileté assemblé de manière permanente à l'intérieur d'un alésage central ou derrière la jante ; le boulon central tubulaire étant conçu pour être fixé par filetage au ou aux éléments filetés pour fixer le dispositif de verrouillage sur la roue, et le cylindre de verrouillage étant conçu pour être agencé dans un état de verrouillage et dans un état ouvert.