baber/WOPTO huggingface dataset:
Patent CA-2559488-A1 (CA)
Title: Method of producing aminophenol compounds
Inventor: KIYOKAWA HIROSHI
IPC: C07D295/08
Filed: 2005-03-25
Abstract: The present invention provides an industrially advantageous method of producing aminophenol compounds represented by the formula (1) by a simple and easy procedure at a high yield and a high purity. The present invention provides a method of producing an aminophenol compound represented by the formula (1): (wherein each of R1 and R2, which may be the same or different, is a hydrogen atom, a substituted or unsubstituted lower alkyl group or the like; R1 and R2, taken together with the adjacent nitrogen atom, may form a 5-or 6-membered heterocycle with or without other intervening heteroatoms; the heterocycle may be substituted by 1 to 3 substituents selected from the group consisting of a hydroxyl group, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted aryloxy group and the like; and the hydroxyl group in the formula (1) is substituted on the 2- or 4-position to the amino group on the phenyl ring), which comprises allowing a cyclohexanedione compound represented by the formula (2) to react with an amine compound represented by the formula (3) (wherein R1 and R2 are as defined above), under a neutral or basic condition.
Patent CA-2560478-A1 (CA)
Inventor: ERDMAN EDWARD
IPC: A61F13/56
Filed: 2006-09-20
Abstract: The use of a drawstring-like design for the elastomeric member in an absorbent article is disclosed. The elastomeric member is attached to the longitudinal axis of the article near its center and covers the back portion of the article forming ear-like structures that have fasteners attached to them so as to fix them to the front portion of the article.
Patent CA-2564855-A1 (CA)
Inventor: MILLER RICHARD L
IPC: A61K39/00
Filed: 2005-04-28
Abstract: The present invention provides pharmaceutical combinations that include an IRM compound formulated for mucosal administration and an antigen formulated for mucosal administration. Additionally, the invention provides methods for immunizing a subject. Generally, the methods include administering an antigen to a mucosal surface of the subject in an amount effective, in combination with an IRM compound, to generate an immune response against the antigen; and administering an IRM compound to a mucosal surface of the subject in an amount effective, in combination with the antigen, to generate an immune response against the antigen.</SDOAB >
Patent CA-2564945-A1 (CA)
Title: Graphic-arts laser imaging with reduced-length laser cavities and improved performance
Inventor: SOUSA JOHN GARY
IPC: B41N3/00
Filed: 2005-05-03
Abstract: Cavity lasers exhibit a relatively high beam quality (e.g., M2<1.25) despite a relatively small cavity length (e.g., 50- 53 mm) for a high (e.g., >= 10 watt) output power device. This enables the construction of physically smaller laser and optical assemblies without sacrificing performance. Reduction of optical photonic interference, which can impair imaging performance, is also facilitated. Laser and optical assemblies may utilize an aperture (154) defined within an optical barrier element (156) to reduce the divergence of the light beam emanating from a diode-pumping laser (112).
Patent CA-2566622-A1 (CA)
Inventor: TAPUSKA DAVID
IPC: H04Q7/32
Filed: 2006-10-25
Abstract: Un dispositif et une méthode pour modifier un contenu de données pour servir sur un appareil électronique portatif. Ce contenu comprend i) un ensemble de fichiers d'images, chacun comportant des donnes graphiques pour la génération d'une image associée; ii) des instructions- machine comprenant des références à l'ensemble de fichiers d'images, permettant aux images en question d'être affichées sur un écran. Plusieurs fichiers d'images sont sélectionnés du contenu et peuvent être combinés de façon à former un seul fichier d'images, fichier qui sera plus petit que la somme des fichiers des images choisies. Les fichiers d'images sont combinés en un seul fichier d'images fusionné. Les instructions-machine sont modifiées pour accepter le fichier d'images fusionné.
Patent CA-2567821-A1 (CA)
Title: Quinazolinone derivatives useful as vanilloid antagonists
Inventor: RITCHIE TIMOTHY JOHN
IPC: C07D239/91
Filed: 2005-06-08
Abstract: The present invention relates to the use of a quinazolinone compound of the formula (I) (see formula I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid antagonist.
Patent CA-2568019-A1 (CA)
Inventor: BASTIAN FRANK O
IPC: A61K39/38
Filed: 2005-05-23
Abstract: Provided is a novel method for detecting Transmissible Spongiform encephalopathies (TSE). The method comprises: selecting a sera sample from a subject to determine whether the subject has transmissible spongiform encephalopathy; and detecting antibodies that immune react with Spiroplasma proteins in the sample. The method detects antibodies in the individual sera samples that react with recombinant Spiroplasma-specific Hsp60 by standard ELISA methodology. This method provides for rapid detection of TSE by determination of presence of antibodies in test sera showing associated Spiroplasma infection that has become consistent with presence of TSE. The method provides a mechanism to detect presence of TSE without invasive techniques currently needed to make diagnosis using brain tissues for prion detection. This method provides means of detection of TSE in the live patient without need for using necropsy tissues. This method provides the first method discovered that detects antibodies against TSE infection-specific proteins in sera or cerebrospinal fluid samples.
Patent CA-2569927-A1 (CA)
Inventor: EHRHART GILLES
IPC: H01L41/39
Filed: 2005-06-16
Abstract: The invention concerns a method for preparing a material based on piezoelectric ceramic oxide(s) comprising the following steps: a) wet deposition on at least one surface of a substrate of a layer of a dispersion comprising a piezoelectric ceramic oxide powder and a piezoelectric ceramic oxide precursor sol-gel solution identical to or different from the piezoelectric oxide constituting the powder; b) repeating a) once or several times, so as to obtain a stack of at least two layers; c) heat-treating said layers so as to transform them into corresponding ceramics; d) wet-shrink impregnation of the stack obtained at c) with a sol-gel solution identical to the one used in step a); e) optionally repeating step d) once or several times; f) heat-treating said stack, so as to transform the sol-gel impregnating the stack into the corresponding piezoelectric ceramics.
Patent CA-2572027-A1 (CA)
Title: Improvements relating to secure telecommunications
Inventor: BARR ROBERT
IPC: G06F21/44
Filed: 2005-06-28
Abstract: A method of carrying out a secure peer-to-peer data communication, such as an e-mail communication, between a first remote party computer and a second remote party computer over a data communications medium is described. The method comprises: receiving the address details and current status of a connection to the data communications medium of each remote party computer;  creating the data communication at the first remote party computer; checking the current connection status of the second remote party computer; and sending the data communication from the first remote party computer directly to the second remote party computer without any storage of the data communication en route, only when the connection status of the second remote party computer indicates that it is currently connected to the data communication medium.
Patent CA-2573043-A1 (CA)
Title: Method of removing a fugitive pattern from a mold
Inventor: REDEMSKE JOHN A
IPC: B29C33/76
Filed: 2005-07-22
Abstract: A method is provided for removing a fugitive pattern, such as wax or other meltable pattern material, residing inside of a refractory mold by discharging condensable vapor such as steam inside the mold to contact and melt the pattern while an exterior of the mold is subjected to a non-condensing gas atmosphere such as air outside of the mold wherein the condensable vapor inside the mold and the atmosphere outside of the mold are at substantially the same pressure. Condensable vapor is condensed inside the mold where the vapor has contacted the pattern while the exterior of the mold remains free of condenate. The condensed vapor and melted pattern material are drained out of the mold. The condensed vapor can be discharged initially inside a hollow sprue of a fugitive pattern assembly to melt the sprue and then inside the mold to melt the patterns of the pattern assembly. The method allows the removal of fugitive pattern materials from molds of any thickness and reduces the cracking of the mold during pattern removal.
Patent CA-2575830-A1 (CA)
Title: Rage fusion proteins and methods of use
Inventor: MJALLI ADNAN M M
IPC: A61K38/17
Filed: 2005-08-03
Abstract: Disclosed are RAGE fusion proteins comprising RAGE polypeptide sequences linked to a second, non-RAGE polypeptide. The RAGE fusion protein may utilize a RAGE polypeptide domain comprising a RAGE ligand binding site and an interdomain linker directly linked to an immunoglobulin CH2 domain. Such fusion proteins may provide specific, high affinity binding to RAGE ligands.  Also disclosed is the use of the RAGE fusion proteins as therapeutics for RAGE-mediated pathologies.
Patent CA-2579924-A1 (CA)
Inventor: RODERT JOERGEN
IPC: B25D9/18
Filed: 2005-09-28
Abstract: Percussion device including a machine housing (l),' a forwards and backwards movable percussion piston (2) in the machine housing, and a reciprocatingly movable valve body (6) in the machine housing, said percussion piston (2) being arranged to , subject a tool (3)' to impacts, and said percussion piston including a first (4) and a- second (5) driving surface intended to be subjected .to pressure in order to drive the percussion piston (2). forwards and backwards, said valve body . ~ ~ (6) including a first end surface (12) and a second end surface (1.3), wherein the pressurizing of the first -end' surface (12) tends to drive the valve body in a first direction- and pressurizing of the second end surface (13) . tends to drive the .valve body in a second direction, whereby the valve body (6) is- arranged, over a channel (7) arranged i the machine housing, to connect at least the second (5) of th driving surfaces alternately to a pressure source (8) or to low pressure (9) , wherein the second end surface (13) , by the percussion .piston (2), is alternately connectable to the pressure source (8) or, over a valve device (11) for creating a counter-pressure, to the low pressure (8) .
Patent CA-2580102-A1 (CA)
Inventor: SCHEIDT WILBUR DOUGLAS
IPC: B23K26/38
Filed: 2007-03-01
Abstract: A system (210, 510, 610) which broadly comprises: (a) a plurality of sensors (222, 226, 522, 526, 532, 654) for monitoring one or more relevant laser drilling process parameters other than only breakthrough (262, 372, 728) during operation of a laser drill (105); and (b) optionally a controller (246) that uses the one or more monitored laser drilling process control parameters to control a laser drill during operation (105) thereof. Also disclosed is a method which broadly comprises the following steps: (a) providing a plurality of sensors (222, 226, 522, 526, 532, 654) capable of monitoring one or more relevant laser drilling process parameters other than only breakthrough (262, 372, 728) during a laser drilling operation (105); (b) monitoring with the plurality of sensors (222, 226, 522, 526, 532, 654) one or more relevant laser drilling process parameters other than only breakthrough (262, 372, 728) during the laser drilling operation (105); and (c) optionally using the one or more monitored laser drilling process parameters to control (246) the laser drilling operation (105).
Patent CA-2581519-A1 (CA)
Title: Blind signal separation using a combination of correlated and uncorrelated antenna elements
Inventor: GOLDBERG STEVEN J
IPC: G10L21/028
Filed: 2005-09-23
Abstract: A communications device for separating source signals provided by M signal sources includes an antenna array comprising N antenna elements for receiving at least N different summations of the M source signals, with N and M being greater than 1. The N antenna elements include at least one antenna element for receiving at least one of the N different summations of the M source signals, and at least two correlated antenna elements for receiving at least two of the N different summations of the M source signals. The at least two correlated antenna elements are uncorrelated with the at least one antenna element. A receiver is connected to the antenna array. A blind signal separation processor is connected to the receiver for forming a mixing matrix comprising the at least N different summations of the M source signals, and for separating desired source signals from the mixing matrix. The mixing matrix has a rank equal up to at least N.
Patent CA-2584583-A1 (CA)
Title: Lyophilized liposome formulations and method
Inventor: ZHANG YUANPENG
IPC: A61K9/19
Filed: 2005-10-28
Abstract: Formulations and methods for preparing a lyophilized composition comprising liposomes comprised of an unsaturated lipid and a hydrophobic drug associated with the liposome, and a cryoprotectant in a solution at a selected concentration. The phase transition temperature of the lipid is greater than the freezing point of the solution at the selected concentration. Preferably the lipid is palmitoyl-oleoylphosphatidylcholine and the cryoprotectant is sucrose.
Patent CA-2585785-A1 (CA)
Inventor: MEHTA ATUL
IPC: B65D65/46
Filed: 2005-10-28
Abstract: A method for packaging plastic material using a film to surround the material, and more particularly to a method for packaging hot melt adhesives, the resulting package formed thereby, and the film composition used therein. The method is preferably a coextrusion process for packaging a pressure sensitive hot melt adhesive by extruding a hot melt adhesive through a die orifice, and coextruding a wax-based polymeric film to surround the hot melt adhesive. The coated adhesive may then be formed into individual packaged units having a finite size and shape. The polymeric film comprises a composition having at least 25% by weight of a wax material, an enthalpy of fusion of at least about 100 J/g, and an elongation value at break of at least about 100%. Any type of hot melt adhesive formulation can be packaged or surrounded by the polymeric film in the process. Also, the specific enthalpy of fusion desired and/or elongation value at break desired for the polymeric film can be obtained by blending an appropriate amount of partially crystalline ethylene-based polymer together with a thermoplastic elastomeric block copolymer and/or an ethylene based or propylene-based elastomer.
Patent CA-2586623-A1 (CA)
Inventor: DEHNHARDT CHRISTOPH
IPC: A61P3/04
Filed: 2005-11-04
Abstract: Methods for synthesizing tetrahydroquinoline-containing compounds of formula (II) are provided, along with synthetic intermediates and products associated with such methods.
Patent CA-2587979-A1 (CA)
Inventor: FUENTES RICARDO
IPC: C12Q1/68
Filed: 2005-11-21
Abstract: Genes, SNP markers and haplotypes of susceptibility or predisposition to hypertension (HT) are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for HT using polymorphisms in the HT risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of HT. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of HT.
Patent CA-2588993-A1 (CA)
Inventor: TOMAZI KEITH G
IPC: C07C209/84
Filed: 2005-11-02
Abstract: L'invention porte sur la séparation économique d'hydrochlorure de benzphétamine et de méthamphétamine par extraction liquide. Elle concerne aussi un procédé d'extraction utilisant un solvant organique convenable et de l'eau présentant un pH compris entre 6 et 8 environ, permettant d'extraire parfaitement de la méthamphétamine par dissolution dans la phase aqueuse alors que la benzphétamine se dissout dans la phase organique. La séparation simple des deux phases entraîne la séparation des deux amines.
Patent CA-2592066-A1 (CA)
Title: Dihydronepetalactams and n-substituted derivatives thereof
Inventor: LIAUW ANN Y
IPC: A01N65/00
Filed: 2005-12-29
Abstract: Dihydronepetalactams and N-substituted derivatives thereof are prepared by alkylation of metallated lactams. Dihydronepetalactams and N-substituted derivatives thereof have utility as insect repellents.
Patent CA-2592574-A1 (CA)
Title: Facilitated cellular reconstitution of organs and tissues
Inventor: DIAMOND PAUL
IPC: A61M1/10
Filed: 2005-12-29
Abstract: One aspect of the invention provides improved methods for the production of at least substantially cellularly human solid organs and solid tissues in non-human mammalian hosts. Related aspects of the invention provide:  transplantation-based methods for obtaining organ and/or tissue-specific gene expression and/or phenotypes with respect to selected cell types and/or at least substantially all cell types of a solid organ or tissue; methods for cellularly reconstituting solid organs and tissues with replacement cells, such as human cells, with respect to selected cell types and/or at least substantially all cell types of an organ or tissue; modified non-human mammals for cellularly reconstituting solid organs and tissues with replacement cells;  and the cellularly reconstituted solid organs and tissues. The production of human organs and tissues according to the invention overcomes the limitations associated with xenotransplantation of animal organs and tissues to humans.
Patent CA-2593119-A1 (CA)
Title: Timing belt tensioner
Inventor: FRANKOWSKI MAREK
IPC: F16H7/12
Filed: 2006-01-18
Abstract: A tensioner for tensioning a flexible drive means includes a pulley mounted on a tensioner arm that can be rotated about a pivot shaft mounted to the tensioner by a spring. The pulley axis is spaced from the tensioner arm axis with respect to the pivot shaft and the spacing of these axes results in the pulley moving through an eccentric towards or away from the belt when the tensioner arm is rotated.  A  stop limits the range of movement of the tensioner arm between a desired range of movement defined by a free arm stop and a backstop. The position of the stop is adjustable. The angular range of tensioner arm movement is adjustable from a position for installation of the tensioner to a position for operation of the tensioner. Optionally, movement of the stop from the installation position to the nominal operating position also compensates the spring.
Patent CA-2594746-A1 (CA)
Inventor: DYSON JAMES
IPC: A47L9/04
Filed: 2005-12-28
Abstract: The invention provides a cleaner head (100) for a cleaning appliance (10; 50) comprising a housing (102) having an upper surface (104) and an underneath surface (106) in which at least one suction opening (108) is arranged, the underneath surface (106) having opposing side edges (106a, 106b), each side edge (106a, 106b) comprising a first part (106c, 106d) which lies adjacent the suction opening or openings (108) and forms a sharply-defined edge with the upper surface (104) and a second part (106e, 106f) which is located rearwardly of the suction opening or openings (108). The second part (106e, 106f) of each of the side edges (106a, 106b) of the underneath surface (106) is upwardly curved. This arrangement is advantageously used in vacuum cleaners or other cleaning appliances in which a ball-type support allows an increased level of steerability involving lateral movement of the cleaner head (100) across the surface to be cleaned. The upwardly curved side edges (106e, 106f) of the underneath surface (106) of the cleaner head (100) reduce the amount of effort required to achieve the steering by presenting a smoothly curved surface to the carpet or other floor covering. At the same time, the first part (106c, 106d) of each side edge (106a, 106b) can be placed close to a wall or skirting board so that good edge cleaning is maintained.
Patent CA-2595275-A1 (CA)
Inventor: PEARCE DAVID
IPC: C22B3/22
Filed: 2007-08-22
Abstract: This invention relates to an improved electrochemical process for winning-platinum group and incidental precious metals from ore. The process utilizes a peroxide leach in combination with electricity to produce higher valency metals and comprises the following steps: combining ground ore a solution comprising water with a selected amount of H2O2 and an anion source to form a slurry, applying a direct current while allowing the metal in the ore to leach into the solution for a selected period of time;  filtering and clarifying the leached slurry to obtain a pregnant solution, and treating the pregnant solution to yield metal, metal salts or both.
Patent CA-2596686-A1 (CA)
Title: Preventive or therapeutic agent for herpesvirus-related disease
Inventor: SUZUKI HIROSHI
IPC: A61K31/4245
Filed: 2006-02-01
Abstract: [PROBLEMS] To provide a medicine, particularly a pharmaceutical composition useful for preventing or treating a variety of diseases caused by infection of a virus of the Herpesviridae family. [MEANS FOR SOLVING PROBLEMS] The present invention relates to an anti-herpesvirus agent characterized by combining a helicase-primase inhibitor with a polymerase inhibitor. By combining the helicase-primase inhibitor with the polymerase inhibitor having different action mechanisms, the anti-herpesvirus agent of the present invention achieves a dramatically superior anti-herpesvirus action compared with conventional administration of a polymerase inhibitor alone. Therefore, it is particularly effective in a case in which a sufficient therapeutic effect cannot be achieved only with a polymerase inhibitor. Further, the doses of both agents can be kept low, therefore it is also possible to perform treatment by lowering the effect of an adverse reaction to be concerned.
Patent CA-2597101-A1 (CA)
Inventor: VELA HERNANDEZ JOSE MIGUEL
IPC: A61K31/465
Filed: 2006-02-10
Abstract: The present invention refers to the use of a sodium channel blocker such as tetrodotoxin or saxitoxin, their analogues and derivatives, their physiologically acceptable salts, as well as their possible combination with nicotine in medicinal products for human and/or animal therapeutics for the treatment of nicotine dependency.
Patent CA-2597240-A1 (CA)
Title: Michael addition product and schiff's base aromachemicals
Inventor: TURIN LUCA
IPC: A23L27/20
Filed: 2006-01-20
Abstract: A pro-odorant or pro-flavorant having the formula (I): wherein R1 is H, an aliphatic group or an aromatic group, R2 is an aliphatic group or an aromatic group, provided that the total number of carbon atoms in the groups R1 and R2 is 10 or more; R3, R4 and R6 are each independently hydrogen or organic moieties which together with C(O)R5 render a compound of formula R5C(O)R6C=CR3R4 a material having odorant or flavourant characteristics and R5 is hydrogen or an organic moiety; or having the formula (II): R8R9C=NR10 wherein R10 is an aliphatic group or an aromatic group having at least 10 carbon atoms; R8 and R9 are each independently hydrogen or organic moieties which together with C=O render a compound of formula R8R9C=O a material having odorant or flavourant characteristics, provided that only one of R8 and R9 is hydrogen; or having the formula (III): wherein R1 is H, an aliphatic group or an aromatic group, R2 is an aliphatic group or an aromatic group, provided that the total number of carbon atoms in the groups R1 and R2 is 10 or more; Z  is CH2 or O, n is 0 or 1, such that the ring is a 5 or 6 membered ring, R11 is alkyl or alkenyl having up to 10 carbon atoms so as to render a compound of formula (IV): a material having odorant or flavorant characteristics is described. Methods for producing these compounds and their use as flavours and fragrances is also described.