baber/WOPTO huggingface dataset:
Patent AU-555980-B2 (AU)
Title: Tri substituted melamines
Inventor: REGNIER GILBERT
IPC: C07D251/70
Filed: 1983-04-20
Granted: 1986-10-16
Abstract: N,N'-substituted polymethylene diamines of the formula:   <IMAGE> in which: A is a hydrocarbon radical from C3 to C5 in a straight or branched chain optionally containing one and two double bonds and possibly substituted by one or more hydroxy radicals; X is CH or nitrogen; n is an integer from 2 to 6; R1 is hydrogen, or alkyl from C1 to C5; R2 is hydrogen, alkyl from C1 to C5, cycloalkyl from C5 to C7, or phenyl optionally substituted by one or more fluorine or chlorine, and B is: phenyl, naphthyl, benzofuranyl, benzothionyl, benzodioxolyl, benzodioxanyl, benzodioxinyl,  DELTA 3-chromenyl, thiochromenyl or chromanyl, each of them optionally substituted by fluorine, chlorine, alkyl or alkoxy from C1 to C5, or methylene-dioxy, or a radical of the formula:    <IMAGE>   in which R3, R4 and R5 which may be the same or different, each represent hydrogen or phenyl optionally substituted by fluorine or chlorine. These compounds and physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of all kinds of tissular hypoxia.
Patent AU-618951-B2 (AU)
Title: Purification of nucleic acids and hybrids thereof by polycationic solid supports
Inventor: ARNOLD LYLE JOHN JR
IPC: C12Q1/6834
Filed: 1988-03-02
Granted: 1992-01-16
Abstract: Described herein is the use of polycationic solid supports in the purification of nucleic acids from solutions containing contaminants. The nucleic acids non-covalently bind to the support without signficant binding of contaminants permitting their separation from the contaminants. The bound nucleic acids can be recovered from the support. Also described is the use of the supports as a means to separate polynucleotides and hybrids thereof with a nucleotide probe from unhybridized probe. Assays for target nucleotide sequences are described which employ this separation procedure.
Patent AU-757466-B2 (AU)
Title: Network for providing switched broadband multipoint/multimedia intercommunication
Inventor: GOLDEN MICHAEL E
IPC: H04L12/56
Filed: 1998-11-10
Granted: 2003-02-20
Abstract: The present invention provides broadband multimedia communication over the standard circuit-switched public switched telephone network infrastructure (PSTN) and other physical or virtual circuit-switched infrastructures while simultaneously and transparently interoperating with the public Internet packet-switched infrastructure to effectively merge the capabilities of the two types of infrastructures into a seamless capability that can bring the benefits of using both types of existing switching infrastructures to large groups of users under the control of the same common and simple interface tools such as web browsers. The invention enables users to establish both packet-switched connections for sending or receiving content for which low-latency and unpredictable response times are not a problem (i.e. text, small graphics, e-mail, small file transfers); and circuit-switched connections for sending or receiving content that benefits from streaming data at fixed data rates, without contention for bandwidth from other users during a communication session, (i.e. video, voice, complex graphics and animations, or large file transfers). The broadband network of the present invention thus mates the convenience of point-and-click on-demand Internet-type packet-switched connectivity with the continuity of a circuit-switch connection, and bundles B channels, or controls connections on virtual circuit switches such as ATM or RSVP for the required bandwidth on-demand for video conferencing and other high-bandwidth applications.
Patent AU-660308-B2 (AU)
Title: Amino acid derivatives
Inventor: MARTIN JOSEPH ARMSTRONG
IPC: C07C271/22
Filed: 1992-05-04
Granted: 1995-06-22
Abstract: Compounds of the formula <CHEM> wherein R<1> represents alkoxycarbonyl, aralkoxycarbonyl, alkanoyl, aralkanoyl, heterocyclylcarbonyl or a group of the formula <CHEM> R<2> represents alkyl, cycloalkylalkyl or aralkyl; R<3> represents hydrogen and R<4> represents hydroxy or R<3> and R<4> together represent oxo; R<5> represents alkoxycarbonyl or alkylcarbamoyl; R<6> and R<7> together represent trimethylene or tetramethylene optionally substituted by alkyl or on adjacent carbon atoms by tetramethylene; R<8> represents alkoxycarbonyl, aralkoxycarbonyl, alkanoyl, aroyl, aralkanoyl or heterocyclylcarbonyl; and R<9> represents alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, cyanoalkyl, carbamoylalkyl, alkylthioalkyl, alkoxyalkyl or alkoxycarbonylalkyl, and pharmaceutically acceptable acid addition salts of those compounds of formula I which are basic, inhibit aspartyl proteases of viral origin and can be used in the form of medicaments for the prophylaxis or treatment of viral infections. They can be manufactured according to generally known methods.
Patent AU-607771-B2 (AU)
Title: Improvements in and relating to fermentation
Inventor: KLAPWIJK PIETER MARIE
IPC: C12N1/04
Filed: 1988-06-07
Granted: 1991-03-14
Abstract: A supported bacterial composition having a water activity of at most 0.2 comprises an inert subdivided support, eg. flour, and aqueous suspension of viable microflora. The composition has improved ambient stability and is usable in fermentation. The composition may contain an accelerant, eg. sucrose.
Patent AU-625150-B2 (AU)
Title: Transdermal therapeutically effective pharmaceutical dressing and device for applying it
Inventor: BURGHART KURT
IPC: A61K9/70
Filed: 1988-05-27
Granted: 1992-07-02
Abstract: A transdermal therapeutically effective pharmaceutical dressing is composed of a film-forming polymer which contains the active ingredient, a liquid polymer matrix which forms a flexible film on hardening, the active ingredient, a solvent which controls the release of the active ingredient and in which the active ingredient is at least partially soluble, a solvent for the matrix which evaporates on the skin, and a propellant. The dressing is contained in a device for metered spraying on to a predetermined surface.
Patent AU-771580-B2 (AU)
Title: Cancer cell vaccine
Inventor: XU MINZHEN
IPC: C12N15/09
Filed: 1999-11-24
Granted: 2004-03-25
Abstract: Disclosed is a specific regulator of Ii protein expression or immunoregulatory function. Specifically disclosed are several forms of the specific regulator of Ii, including those which function through the formation of a duplex molecule with an RNA molecule encoding mammalian Ii protein to inhibit Ii protein synthesis at the translation level. This class includes copolymers comprised of nucleotide bases which hybridize specifically to the RNA molecule encoding mammalian Ii protein, and also expressible reverse gene constructs. In other aspects, the disclosure relates to MHC class II-positive antigen presenting cells containing a specific regulator of Ii expression. Such cells are useful, for example, in the display of autodeterminant peptides in association with MHC class II proteins. Compositions of the invention find application in methods for treating diseases, for example malignancies and autoimmune disorders, in a patient by enhancing immunological attack on undesired cells. An additional application is the isolation of autodeterminant peptides from a cell.
Patent AU-718361-B2 (AU)
Title: Camptothecin derivatives and the use thereof as antitumor agents
Inventor: MERLINI LUCIO
IPC: A61K31/47
Filed: 1997-02-19
Granted: 2000-04-13
Abstract: PCT No. PCT/EP97/00786 Sec. 371 Date Aug. 20, 1998 Sec. 102(e) Date Aug. 20, 1998 PCT Filed Feb. 19, 1997 PCT Pub. No. WO97/31003 PCT Pub. Date Aug. 28, 199720S-Camptothecin derivatives in which the 7-position bears as a substituent -CN, -CH(CN)R4, -CH=C(CN)R4, -C(=NOH)NH2, -C(=NH)NH2, -CH=C(NO2)R4, -CH(CN)R5, -CH(CH2NO2)R5, tetrazol-5-yl, 4,5-dihydrooxazol-2-yl, or 1,2,4-oxadiazolin-3-yl-5-one. These compounds are active as topoisomerase I inhibitors, and can be used as antitumor drugs.
Patent AU-730018-B2 (AU)
Title: Manufacture of paper
Inventor: GREENWOOD GRAHAM
IPC: D21H27/10
Filed: 1997-03-11
Granted: 2001-02-22
Abstract: Starch is added to the thinstock in a papermaking process in the form of a coagulated slurry containing undissolved starch particles, cationic polymeric flocculant and anionic microparticulate network agglomeration aid, such as bentonite. The flocculant and agglomeration aid interact to give network flocculation in which the starch particles are trapped. Improved retention of the starch in the resulting paper is achieved.
Patent AU-699483-B2 (AU)
Title: Sulphonamide derivatives as aspartyl protease inhibitors
Inventor: TUNG ROGER DENNIS
IPC: C07D263/22
Filed: 1995-02-24
Granted: 1998-12-03
Abstract: PCT No. PCT/US95/02420 Sec. 371 Date Apr. 1, 1996 Sec. 102(e) Date Apr. 1, 1996 PCT Filed Feb. 24, 1995 PCT Pub. No. WO95/24385 PCT Pub. Date Sep. 14, 1995This invention provides a novel class of sulfonamide compounds of formula I which are aspartyl protease inhibitors: This invention also provides pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also provides methods for inhibition aspartyl protease activity and methods for treating viral infections using the compounds and compositions of this invention.
Patent AU-699007-B2 (AU)
Title: Peptide fragments of microbial stress proteins and pharmaceutical composition made thereof for the treatment and prevention of inflammatory diseases
Inventor: ANDERTON STEPHEN MARK
IPC: A61K38/08
Filed: 1995-03-21
Granted: 1998-11-19
Abstract: Peptides are provided which are useful for protection against or treatment of an inflammatory disease, including autoimmune diseases, such as diabetes, arthritic diseases, atherosclerosis, multiple sclerosis, myasthenia gravis, or inflammatory responses due to tumour or transplant rejection. The peptides contain a part of the aminoacid sequence of a microbial protein having a conserved mammalian stress protein homologue, wherein the overall aminoacid sequence identity between the microbial and the mammalian homologues is at least 25 %, and the sequence identity between the microbial and the mammalian homologues of an area of at least 75 consecutive aminoacids is at least 30 %, said part comprising at least 5 aminoacids which are in the same relative position as the same aminoacids in a T cell epitope of said stress protein, which epitope contains at least 4 consecutive aminoacids which are identical with the corresponding mammalian stress protein aminoacids. Nucleotide sequences, expression systems, antibodies and pharmaceutical and diagnostic compositions derived from these peptides are provided as well.
Patent AU-595769-B2 (AU)
Title: Clip for flanges of forms in formworks
Inventor: MERKEL JOSEF
IPC: E04G17/04
Filed: 1988-07-28
Granted: 1990-04-05
Abstract: A clip for abutting marginal flanges of forms for formworks which are used for the pouring of concrete has a cylindrical housing for two slidable arcuate clamping elements at opposite sides of a radially extending recess for the flanges. A wedge is movable between those end portions of the clamping elements which are remote from the recess to urge the elements against the exposed sides of the flanges. The wedge can be slidably coupled to the clamping elements so that it can urge the elements against or disengage the elements from the flanges in the recess.
Patent AU-679359-B2 (AU)
Title: Electronic-monetary system
Inventor: ROSEN SHOLOM S
IPC: G06F19/00
Filed: 1995-05-18
Granted: 1997-06-26
Abstract: An improved monetary system using electronic media to exchange economic value securely and reliably. The invention provides a complete monetary system having electronic money that is interchangeable with conventional paper money comprising (1) issuing banks or financial institutions that are coupled to a money generator device for generating and issuing to subscribing customers electronic currency backed by demand deposits electronic credit authorizations; (2) correspondent banks that accept and distribute the electronic money; (3) a plurality of transaction devices that are used by subscribers for storing electronic money, for performing money transactions with the on-line systems of the participating banks or for exchanging electronic money with other like transaction devices; (4) automated teller devices, associated with the issuing and correspondent banks, for process handling and interfacing the transaction devices to the issuing and correspondent banks, and for interfacing between the issuing and correspondent banks themselves; and (5) a clearing bank for balancing the electronic money accounts of the different issuing banks (6).
Patent AU-657980-B2 (AU)
Title: Transporting element of a reciprocable scraper for moving sludge in settling basins and similar objects at water purification plants
Inventor: ZICKERT KLAUS DIETER
IPC: E03F5/10
Filed: 1992-07-30
Granted: 1995-03-30
Abstract: The present invention relates to a transporting element (8) of a reciprocable scraper for the movement of sludge in settling basins (1) and similar objects at water purification plants, whereby the transporting element (8) consists of a body, which in cross-section shows a downwardly facing surface (9), a substantially oblique, convex surface (10), and a substantially vertical concave surface (11), whereby the concave surface (11) is directed in the forwarding, transporting direction. <IMAGE>
Patent AU-653054-B2 (AU)
Title: Preparation of sulphate poly aluminium chloride solution
Inventor: HAAKE GERHARD
IPC: C01F7/786
Filed: 1992-06-24
Granted: 1994-09-15
Abstract: In prepn.of basic poly-Al chloride solns. (I) contg. sulphate, (a) substances contg. Al are decomposed with HCl, (b) insol. residue is filtered off, (c) the soln. is evaporated, (d) AlCl3.6H2O is recovered by crystallisation from the soln., (e) the AlCl3.6H2O is converted to a solid, basic Al chloride by thermal decomposition at 150-200 deg. C, (f) the solid, basic Al chloride is dissolved in aq. H2SO4, with formation of Al(OH)xCly(SO4)z, and (g) the basic Al chloride-sulphate soln. is heated at 40-70 deg. C for 1-3 hours. The Al-contg. substance is pref. a waste prod. The soln. is pref. evaporated to 30 wt.% AlCl3 content. The AlCl3.6H2O pref. has particle dia. 250-450 microns and 3-10 wt.% residual moisture. The basicity, OH:Al = 1.35-2.25:1. Heating is in a vortex layer. The basic Al chloride is pref. dissolved in water before soln. in H2SO4. Dissolution in water or in aq. H2SO4 is at 40-70 deg. C, to a soln. contg. 3-10 (5-7.5) wt.% Al. After heating, the basic Al chloride-sulphate soln. pref. has OH:Al = 1.05-1.95:1, and 1-6 (2-4) wt.% sulphate content, and is then filtered.
Patent AU-693552-B2 (AU)
Title: Calcium free subtilisin mutants
Inventor: BRYAN PHILIP N
IPC: C12P21/02
Filed: 1995-04-28
Granted: 1998-07-02
Abstract: Novel calcium free subtilisin mutants are taught, in particular subtilisins which have been mutated to eliminate amino acids 75-83 and which retain enzymatic activity and stability. Recombinant methods for producing same and recombinant DNA encoding for such subtilisin mutants are also provided.
Patent AU-652076-B2 (AU)
Title: Novel amidinonaphthyl furancarboxylate derivatives and acid addition salts thereof
Inventor: NAKAYAMA TOYOO
IPC: A61P37/00
Filed: 1992-09-28
Granted: 1994-08-11
Abstract: Amidinonapththyl furancarboxylate derivatives of the formula I <CHEM>  wherein A is a single bond or A denotes     a) a phenyl group, a cyclopentyl group or a cyclohexyl group; b) an alkenylphenyl group, an alkylphenyl group, a phenylalkenyl group or a phenylalkyl group wherein alkyl is C1 to C7 alkyl and alkenyl is C1 to C7 alkenyl; c) a C1 to C18 alkyl or C1 to C7 alkenyl group, which may be substituted by one or two substituents selected from C1 to C5 alkyl groups and guanidino groups, wherein an alkyl substituent together with the carbon atom to which it is attached, may form a cycloalkyl ring having from 3 to 6 carbon atoms, or a C1 to C5 alkyl may itself be substituted by a cycloalkyl ring; or d) -(CH2)n-NH-CO-(CH2)n<'>- wherein n and n', which may be the same or different, each represent an integer from 1 to 4; and R denotes a hydroxyl group; a C1 to C7 alkoxy group which may be mono- or di-substituted by C1 to C5 alkyl; a phenyl-C1-C4alkoxy group; -OAl(OH)2; an amino group; <CHEM> and pharmaceutically acceptable acid addition salts thereof are useful as pharmaceuticals.
Patent AU-616006-B2 (AU)
Title: Method and system for compressing and decompressing digital color video statistically encoded data
Inventor: MUSIC JOHN
IPC: H04N7/32
Filed: 1989-03-23
Granted: 1991-10-17
Abstract: The method and system for compressing and decompressing digital color video data utilizes a plurality of digitized signals representing combinations of run lengths and compressed color component codes, and a look up table of the digitally compressed color codes. The digitally compressed color component codes are decoded according to the look up table to form a table of the three digital color components for each run length, and the run lengths and corresponding color components are stored in an array in a buffer memory to represent the scan lines in a video picture frame.
Patent AU-711468-B2 (AU)
Title: Compositions and methods for protein structural determinations
Inventor: BROWN JONATHAN MILES
IPC: C12P13/04
Filed: 1997-08-28
Granted: 1999-10-14
Abstract: A method for determining three-dimensional structural information of a protein involves producing the protein in a form substantially labeled with <13>C or <15>N or both or substantially labeled with <15>N and <13>C and partially labeled with <2>H and subjecting the protein to nuclear magnetic resonance spectroscopic analysis. The isotopically labeled protein is produced by a method which involves producing a substantially labeled microbial protein hydrolysate, subjecting the protein hydrolysate to cation exchange chromatography to produce a partially purified labeled amino acid mixture, subjecting the partially purified labeled amino acid mixture to anion exchange chromatography to produce a purified labeled amino acid mixture and supplementing the purified labeled amino acid mixture with isotopically labeled cysteine and optionally with isotopically labeled glutamine and asparagine.
Patent AU-721499-B2 (AU)
Title: Method for the deburring of items, particularly items of metal, and use of the method
Inventor: HUNDEBOL KELD OTTING
IPC: B24B9/00
Filed: 1997-08-05
Granted: 2000-07-06
Abstract: PCT No. PCT/DK97/00326 Sec. 371 Date Mar. 23, 1998 Sec. 102(e) Date Mar. 23, 1998 PCT Filed Aug. 5, 1997 PCT Pub. No. WO98/05472 PCT Pub. Date Feb. 12, 1998The invention is a method for deburring items, especially metal items which have sharp edges or burrs resulting from punching, clipping, molding or other machine operations. The items are fed under a deburring tool which sweeps the surface of the items, the deburring tool having a number of deburring rollers, each secured to an individual rotatable spindle axle which extends radially outward from a drive. The deburring rollers rotate around the spindle axles while all the spindle axles are also being turned around a turning axle which extends at a right angle to the spindle axles. The deburring rollers are also moved in a reciprocating manner in a direction transverse to the feeding direction. The method is of particular use in the deburring of ribs for aircraft wines and other similar items.
Patent AU-577352-B2 (AU)
Title: Acrylic polymers containing ethylenic non-ionic surfactant comonomers
Inventor: HAAS RAIMUND
IPC: C10M173/02
Filed: 1985-02-08
Granted: 1988-09-22
Abstract: Aqueous functional fluids, in particular hydraulic and metal-working fluids, containing a copolymer which is prepared by emulsion or solution copolymerization, initiated by free radicals, of unsaturated, copolymerizable monomers, the copolymers being built up from: (a) 1-60% by weight of ethylenically unsaturated carboxylic acids, (b) 0.5-30% by weight of a surface-active unsaturated ester, (c) 30-85% by weight of methacrylic acid esters or acrylic acid esters of aliphatic (C1-C18)-alcohols, (d) 0-40% by weight of other ethylenically unsaturated comonomers, (e) 0-3% by weight of polyethylenically unsaturated compounds, and (f) 0-5% by weight of molecular weight regulators, and, if appropriate, the free acid groups of the copolymers subsequently having been partly or completely neutralized by addition of bases, and converted into water-soluble or colloidally water-dispersible copolymer salts.
Patent AU-688164-B2 (AU)
Title: Metalloproteinase inhibitors
Inventor: BECKETT RAYMOND PAUL
IPC: C07C237/22
Filed: 1995-11-27
Granted: 1998-03-05
Abstract: PCT No. PCT/GB95/02770 Sec. 371 Date May 21, 1997 Sec. 102(e) Date May 21, 1997 PCT Filed Nov. 27, 1995 PCT Pub. No. WO96/16931 PCT Pub. Date Jun. 6, 1996Compounds of general formula (I), principally characterized in that R4 is a polyether group, are water soluble matrix metalloproteinase inhibitors.    <IMAGE>  (I)
Patent AU-684409-B2 (AU)
Title: Chemiluminescent dialkyl-substituted 1,2-dioxetane compounds, methods of synthesis and use
Inventor: SCHAAP ARTHUR PAUL
IPC: C07C69/78
Filed: 1995-11-02
Granted: 1997-12-11
Abstract: A chemiluminescent assay method and compositions are described which use a dialkyl-substituted dioxetane which is deprotected to trigger a chemiluminescent reaction. Chemiluminescent 1,2-dioxetane compounds substituted on the dioxetane ring with two nonspirofused alkyl groups which can be triggered by a reagent to generate light are disclosed. Dialkyl-substituted dioxetanes are useful for the detection of triggering agents including enzymes. The enzyme may be present alone or linked to a member of a specific binding pair in an immunoassay, DNA probe assay or other assay where the enzyme is bound to a reporter molecule.
Patent AU-781302-B2 (AU)
Title: Camptothecin analogs and methods of preparation thereof
Inventor: CURRAN DENNIS P
IPC: C07D491/044
Filed: 2000-04-07
Granted: 2005-05-12
Abstract: A compound having the formula in racemic form, enantiomerically enriched form or enantiomerically pure form, and pharmaceutically acceptable salts thereof.
Patent AU-701050-B2 (AU)
Title: Heat and moisture exchanger
Inventor: NILSON BILLY
IPC: A61M16/16
Filed: 1995-11-30
Granted: 1999-01-21
Abstract: PCT No. PCT/SE95/01444 Sec. 371 Date May 29, 1997 Sec. 102(e) Date May 29, 1997 PCT Filed Nov. 30, 1995 PCT Pub. No. WO96/16689 PCT Pub. Date Jun. 6, 1996A moisture-heat exchange arrangement which is intended for connection to a patient to humidify and heat the air inhaled by the patient, wherein the arrangement includes a moisture-heat exchanger unit (5) and a humidifier means (11, 12) that connects with the unit (5) to increase the humidity of the inhalation air. The humidifying means includes a casing (3) which is connected with the moisture-heat exchanger unit (5) and which has a first opening (9) that communicates with the moisture-heat exchanger unit and an opposing opening (6) that communicates with the patient. The inner surface of the casing has provided thereon a water-absorbing and/or water-vapour permeable material (11) which delivers moisture to the air inhaled by the patient.
Patent AU-693986-B2 (AU)
Title: Epoxy-functional polyethers
Inventor: ELMORE JIMMY D
IPC: C08G59/16
Filed: 1995-12-20
Granted: 1998-07-09
Abstract: A novel epoxy-functional polyether composition is produced by reacting (a) a carboxylic acid having formula formula (VI), wherein R<1> is a C1-C15 alkyl, aryl or alkylaryl and X and Y are independently a hydrogen, methyl or ethyl group with the provision that if X is methyl or ethyl, Y is hydrogen or if Y is methyl or ethyl, X is hydrogen and n + m is a real number from 4 to 450 and (b) an epoxy resin having a functionality of at least 1.5 epoxide group per molecule.