baber/WOPTO huggingface dataset:
Patent DK-0717036-T3 (DK)
Inventor: HEINE HANS-GEORG DR
IPC: C07D211/82
Filed: 1995-12-04
Granted: 1999-10-11
Abstract: The use of 1-alkyl-3,5-diacyl-2,6-dimethyl-6-aryl-1,4-dihydropyridines of formula (I) is claimed in the prepn. of selective potassium channel modulating medicaments for treating CNS disorders. R1 = 6-10C aryl (opt. substd. by 1-5 of NO2, CN, halogen, CF3 and 1-6C alkylthio); R2 = 1-8C alkyl, phenyl, 1-8C alkoxy or phenoxy; R3 = 1-8C alkyl or phenyl; R4 = 1-4C alkyl. The following cpds. (I) are new: 1-(5-acetyl-4-(R')-1,2,6-trimethyl-1,4-dihydropyridin-3-yl)-ethanone; and 5-acetyl-4-(R")-1,2,6-trimethyl-1,4-dihydropyridine-3-carboxylic acid methyl ester. R' = 2,4,5-, 2,3,5- or 3,4,5-trichlorophenyl, 2,3- or 3,4-dichlorophenyl, 4-chlorophenyl or 4-fluorophenyl; R" = 4-chlorophenyl, 2,3- or 3,4-dichlorophenyl, 3- or 4-nitrophenyl, 3,4,5-trifluorophenyl, 4-fluorophenyl or 4-chloro-3-trifluoromethylphenyl. The prepn. of new and known (I) is claimed (see 'Preparation').
Patent DK-0755214-T3 (DK)
Inventor: ARNOLD HANS PETER
IPC: A47L9/04
Filed: 1995-03-27
Granted: 1999-06-07
Abstract: The invention relates to a flow channel section (S), especially for a vacuum cleaner (1), in which there is a pivot joint (18) and a diagonal intermediate section (15) is formed from an inlet channel which, once again with a further deviation, opens into an outlet channel, the cross section of the inlet channel (13) and the outlet channel (17) being elliptical, the pivot joint (18) being formed in the intermediate section (15), and the cross section of the channel being circular. In order to design a flow channel section (S), especially for a vacuum cleaner, as claimed, so that the best possible flow conditions are maintained over the greatest possible pivoting range about the pivot joint (18) and/or the air flow (L) is deflected in such a way that sharp deflection areas are avoided, with a relatively small flow channel section (S), it is proposed that the intermediate section (15) be directed along a somewhat spatially diagonal line (axis x).
Patent DK-0769144-T3 (DK)
Inventor: LA THANGUE NICHOLAS
IPC: C12Q1/04
Filed: 1995-07-03
Granted: 2000-05-08
Abstract: PCT No. PCT/GB95/01567 Sec. 371 Date Feb. 26, 1996 Sec. 102(e) Date Feb. 26, 1996 PCT Filed Jul. 3, 1995 PCT Pub. No. WO96/01425 PCT Pub. Date Jan. 18, 1996The protein DP-1, part of the DP-1/E2F-1 transcription factor complex, as well as DP-2 and DP-3 has its phosphorylation level regulated during cell cycle progression. This finding allows assays to be based on changes in phosphorylation of DP proteins, in particular for agents which may affect the phosphorylation state of DP. DP-1 has been found to have a greater affinity to DNA when in a hypophosphorylated state. Antibodies that recognize phosphorylation sites on DP-1 are also disclosed.
Patent DK-0776337-T3 (DK)
Inventor: LEE SE-JIN
IPC: C12N5/06
Filed: 1995-07-07
Granted: 2005-12-12
Abstract: Growth Differentiation Factor-11 (GDF-11) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-11 polypeptide and polynucleotide sequences.
Patent DK-0778827-T3 (DK)
Inventor: KOTTENHAHN MATTHIAS
IPC: C07D209/48
Filed: 1995-08-17
Granted: 2002-04-08
Abstract: A process for producing 2-[3(S)-amino-2-(R)-hydroxyl-4-phenyl butyl]-N-tert,butyl decahydro-(4aS,8aS)-isoquinoline-e(S)-carboxamide of the formula (I) via 3(S)-[lower alkoxy carbonyl amino, phenoxy carbonyl amino or benzyl oxycarbonyl amino]-2-hydroxy-4-phenyl butyric acid and process for producing said acid.
Patent DK-0793656-T3 (DK)
Inventor: JOLIDON SYNESE
IPC: A61P31/04
Filed: 1995-11-13
Granted: 2003-07-21
Abstract: PCT No. PCT/EP95/04451 Sec. 371 Date May 21, 1997 Sec. 102(e) Date May 21, 1997 PCT Filed Nov. 13, 1995 PCT Pub. No. WO96/16046 PCT Pub. Date May 30, 1996Compounds of the formula:    <IMAGE>  I  in which R1 is lower alkoxy, R2 is bromine or lower alkoxy, and R3 is aryl, heteroaryl or a group -Q-R30, wherein Q is ethylene, vinylene or ethynylene and R30 is aryl, heteroaryl, lower alkoxycarbonyl or carbamoyl; hydrolyzable esters of carboxylic acids of formula I; and pharmaceutically acceptable salts of these compounds are useful for treating infectious diseases.
Patent DK-0781896-T3 (DK)
Inventor: TROJAHN WERNER
IPC: F01D15/06
Filed: 1996-12-23
Granted: 2001-09-03
Abstract: The turbine wheel has a disc wheel body (1) with a central bearing mounting opening (2) with concentric inlet openings (3) at the periphery on one disc side (3), and driving air channels (5) from the disc body each opening into an outlet (14). The outlet openings (14) are at the peripheral surface (7) of the wheel disc. The drive air channels have an axial inflow section (6) and an outflow section (8) in the wheel disc body towards the circumference surface.
Patent DK-0809652-T3 (DK)
Inventor: PFLAUM ZLATKO
IPC: C07K1/14
Filed: 1996-02-06
Granted: 2003-12-08
Abstract: PCT No. PCT/SI96/00003 Sec. 371 Date Jul. 28, 1997 Sec. 102(e) Date Jul. 28, 1997 PCT Filed Feb. 6, 1996 PCT Pub. No. WO96/24615 PCT Pub. Date Aug. 15, 1996The present invention discloses a new process for the purification of vancomycin hydrochloride by combining preparative chromatography on a silica gel column and the precipitation with ethanol from a salt-water-ethanolic solution without intermediary filtering, whereby the chromatographic purity of the product is improved. The chromatography is carried out on a column containing a silica gel stationary phase and an alkaline water-methanolic mobile phase at defined pH, mobile phase flow and temperature as well as the amount and concentration of vancomycin hydrochloride. The process is distinguished by the yield and chromatographic purity of the obtained product of about 93% area. Vancomycin hydrochloride purified according to the present invention is useful for peroral as well as parenteral administration since the portion of impurities it contains is for one third smaller than in hitherto available product.
Patent DK-0828758-T3 (DK)
Inventor: IBEA MICHEL
IPC: C07K19/00
Filed: 1996-05-22
Granted: 2002-01-07
Abstract: The present invention relates to chimeric fatty body-pro-GRF analogs with increased biological potency, their application as anabolic agents and in the diagnosis and treatment of growth hormone deficiencies. The chimeric fatty body-pro-GRF analogs include an hydrophobic moiety (tail), and can be prepared, either by anchoring one or several hydrophobic tails to the GRF, or by substituting one or several amino-acids by a pseudomicellar residue in the chemical synthesis of GRF. The GRF analogs of the present invention are biodegradable, non-immunogenic and exhibit an improved anabolic potency with a reduced dosage and prolonged activity.
Patent DK-0830379-T3 (DK)
Inventor: CHIU CHUNG-WAI
IPC: A23L29/20
Filed: 1996-05-16
Granted: 2003-11-24
Abstract: Described is a food containing a starch or flour which has been prepared by a process, which comprises the steps of pregelatinizing a starch or flour using a process which disrupts the granular structure, and thermally inhibiting the starch or flour by dehydrating, thermally or non-thermally, the starch or flour to anhydrous or substantially anhydrous and heat treating the dehydrated starch or flour for a time and at a temperature sufficient to thermally inhibit the starch or flour.
Patent DK-0837871-T3 (DK)
Inventor: SCHMIDT HELMUT
IPC: C12Q1/68
Filed: 1996-06-06
Granted: 2003-08-25
Abstract: New prods. are (a) magnetic particles with an external glass surface that is nonporous or has pores with a dia. below 10 nm and (b) ferromagnetic particles with a glass surface.
Patent DK-0881162-T3 (DK)
Inventor: SCHMITZ HEINZ JUERGEN
IPC: B65D77/20
Filed: 1997-04-22
Granted: 1999-09-27
Abstract: The cover foil (3) is sealed to the edge of the dish (1) which is made mainly from natural particles, fibres or starch. The connecting strength between the foil and surface particles is greater than the connecting strength between the surface particles and the rest of the dish material. The cover foil comprises a lower melting material on the dish side than on the side remote from the dish. The pressure used when sealing is so great that the surface of the dish material undergoing sealing is smoothed out.
Patent DK-0932592-T3 (DK)
Inventor: AHARON MEIR EYAL
IPC: C07C51/48
Filed: 1997-10-02
Granted: 2002-09-02
Abstract: The invention provides a process for the recovery of lactic acid and products thereof from an aqueous solution containing free lactic acid and at least one lactate salt at a total concentration of at least 5%, the process comprising the steps of: extracting at least 70% of the free lactic acid from the aqueous solution by contacting the solution with a basic extractant, to form a lactic acid-containing extract and a lactic acid-depleted, lactate salt-containing aqueous solution; separating the lactic acid-containing extract from the depleted aqueous solution; and stripping the extracted lactic acid from the extract by methods known per se, to form a solution of lactic acid and a stripped extractant.
Patent DK-0904067-T3 (DK)
Inventor: HOECK ULLA
IPC: A61K31/485
Filed: 1997-03-21
Granted: 2005-03-14
Abstract: The present invention is drawn to a device for the transdermal administration of dextromethorphan, (+)-3-methoxy-17-methyl-9a,13a,14a-morphanin, and salts, prodrugs and metabolites thereof, together with a pharmaceutically acceptable carrier, to a human being or animal in need thereof, to achieve an antitussive effect. The present invention is further drawn to a method of achieving an antitussive effect in a human being or animal which comprises transdermally administering dextromethorphan, (+)-3-methoxy-17-methyl-9a,13a,14a-morphanin, and salts, prodrugs and metabolites thereof, together with a pharmaceutically acceptable carrier.
Patent DK-0973408-T3 (DK)
Inventor: BEER RICHARD
IPC: A23G9/32
Filed: 1997-07-23
Granted: 2002-03-11
Abstract: The invention relates to a method for the production of ice cream containing soft and/or pasty chip-shaped added ingredients, such as fruit or chocolate. The invention also relates to the ice cream products obtained by this method.
Patent DK-0938486-T3 (DK)
Inventor: TRAXLER PETER
IPC: A61K31/519
Filed: 1997-08-21
Granted: 2008-07-07
Abstract: There are described 7H-pyrrolo[2,3-d]pyrimidine derivatives of the formula Iin which the substituents are as defined in claim 1.These compounds inhibit the tyrosine kinase activity of the receptor for the epidermal growth factor (EGF) and c-erbB2 kinase and can be used as anti-tumor agents.
Patent DK-0944332-T3 (DK)
Inventor: KUERZINGER HUBERT
IPC: A23K50/80
Filed: 1997-12-03
Granted: 2004-03-22
Abstract: Novel flake feeds are described, especially for aquatic animals, such as fish, shrimps and invertebrates, characterized in that the flakes have a uniform form, a variable thickness and a water content of from 1 to 30%, as well as a process for the production thereof.
Patent DK-0917874-T3 (DK)
Inventor: CINCOTTA ANTHONY
IPC: A61K38/22
Filed: 1991-01-07
Granted: 2008-07-28
Abstract: A process for the long term modification and regulation of lipid metabolism -- generally to reduce obesity, insulin resistance, and hyperinsulinemia or hyperglycemia, or both (these are the hallmarks of noninsulin dependent, or Type II diabetes) -- by administration (i.e., by feed or injection into the bloodstream) to a vertebrate, animal or human, of a dopamine agonist, e.g., bromocriptine. Administration of the bromocriptine is made over a limited period at a time of day dependent on the normal circadian rhythm of fat and lean members of a similar species. Decreases in body fat deposits result by treatment of an obese species on a daily timed sequence based on circadian rhythms of the peak prolactin, or peak prolactin and peak glucocorticosteroid, blood level established for lean members of a similar species. Insulin resistance, and hyperinsulinemia and hyperglycemia, or both, can also be controlled in humans on a long term basis by treatment corresponding to that of the treatment for obesity. The short term daily injections reset hormonal timing in the neural centers of the brain to produce long term effects.
Patent DK-0964677-T3 (DK)
Inventor: GOLDENHEIM PAUL D
IPC: A61K31/485
Filed: 1998-02-24
Granted: 2006-12-11
Abstract: A sustained release formulation of buprenorphine is new. The composition comprises a transdermal delivery device which provides a first order release of buprenorphine over a 3-day dosing interval so that a maximum plasma concentration of 20 10 1052 pg/ml is obtained. the device then provides zero order kinetics over at least 2 more days.
Patent DK-0992041-T3 (DK)
Inventor: GROSS LAURENCE HERBERT
IPC: C08L23/08
Filed: 1998-06-19
Granted: 2006-01-16
Abstract: A composition comprising: (i) a homopolymer of ethylene made by a high pressure process, and, based on 100 parts by weight of component (i), (ii) about 2 to about 15 parts by weight of a copolymer of ethylene and an acrylic acid ester or methacrylic acid ester, said ester being present in the copolymer in an amount of about 10 to about 30 percent by weight based on the weight of the copolymer; and (iii) about 0.03 to about 0.3 part by weight of a polyethylene glycol having a molecular weight in the range of about 1000 to about 100,000.
Patent DK-0996615-T3 (DK)
Inventor: RODRIGUEZ GUSTAVO A
IPC: A23K1/18
Filed: 1998-07-17
Granted: 2003-01-20
Abstract: A method of isomerizing lutein to yield a mixture of epimers of zeaxanthin includes the following steps: mixing a lutein-containing extract in a glycol solution to obtain a mixture, treating the mixture with alkali to obtain an alkali-containing mixture, reacting the alkali-containing mixture in the presence of heat for a duration consistent with achieving a desired level of isomerization of lutein to zeaxanthin.
Patent DK-1000035-T3 (DK)
Inventor: FLOCKERZI DIETER
IPC: A61P1/00
Filed: 1998-07-18
Granted: 2003-03-17
Abstract: PCT No. PCT/EP98/04478 Sec. 371 Date Jan. 24, 2000 Sec. 102(e) Date Jan. 24, 2000 PCT Filed Jul. 18, 1998 PCT Pub. No. WO99/05113 PCT Pub. Date Feb. 4, 1999The invention relates to compounds of formula (I): wherein R1, R2, R3, R31, R4, R5, R51 and R6 are as defined in the specification. The compounds are phosphodiesterase inhibitors. Also disclosed are pharmaceutical compositions and methods of use of the compounds.
Patent DK-1040097-T3 (DK)
Inventor: CARROLL WILLIAM A
IPC: C07D495/04
Filed: 1998-12-16
Granted: 2004-08-02
Abstract: Compounds having the formula  are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
Patent DK-0933136-T3 (DK)
Inventor: HUMPERT JUERGEN
IPC: B05B1/16
Filed: 1999-01-21
Granted: 2004-05-03
Abstract: The tap is turned on and off using a lever (4) pivotably mounted in the fitting casing (1) and joined at one end to a valve member (20) for a switch valve (2), this member being positioned upstream from the tap nozzle (51). A region (40) of the lever outside the fitting casing acts as the handle, the cross-section dimensions of the casing and handle being chosen to allow them to be grasped by one hand.
Patent DK-0985421-T3 (DK)
Inventor: BENNETT CYNTHIA A
IPC: A61M5/168
Filed: 1997-01-23
Granted: 2003-12-01
Abstract: The present invention provides an infusion pump having a main body portion. The main body portion includes a display area for displaying user interface information. At least one pump module is provided which is removably secured to the main body portion and adapted to receive an IV tube. The pump module includes means for applying pumping action to the IV tube. A microprocessor is contained in the main body portion for generating user interface information on the display area. The infusion pump also comprises means for sensing tube restrictions and included in the user interface information is a graphical representation of the degree to which the tube is restricted. <IMAGE>
Patent DK-1126846-T3 (DK)
Inventor: CARLSSON MARIA
IPC: A61P25/22
Filed: 1999-10-29
Granted: 2003-09-29
Abstract: Use of a nicotine receptor agonist or a pharmaceutically acceptable salt thereof for the production of a pharmaceutical preparation for the treatment of obsessive compulsive disorder is disclosed, as well as a method for treatment of a patient suffering from obsessive compulsive disorder, comprising the administration of a nicotine receptor agonist or a pharmaceutically acceptable salt thereof, in an amount effective in alleviating, reducing or abolishing one or several of the symptoms of obsessive compulsive disorder.
Patent ES-2231060-T3 (ES)
Inventor: SCHULZ HARTMUT DR-ING
IPC: D21H11/22
Filed: 2000-03-11
Granted: 2005-05-16
Abstract: The raw lamination paper is composed of cellulose fibers and filling materials from a paper mass of a cellulose mixture containing an unmodified and a cationic modified cellulose.  The modified cellulose has a cation charge of 20-300 mmol/kg. The cellulose fibers are modified with a quaternary ammonium compound with a glycidyl function. The cationic modified cellulose forms at least 5 wt% of the cellulose mixture, using a short fiber cellulose for modification. The paper mass contains a wet strength agent in a vol. of 0.3-2.0 wt% of the cellulose. The filling material is titanium oxide, calcium carbonate, kaolin, talcum or a mixture of them.
Patent ES-2234476-T3 (ES)
Inventor: KUNTZE CHRISTOPH
IPC: C22C38/06
Filed: 2000-05-08
Granted: 2005-07-01
Abstract: A hot rolled armor plate is made of a low carbon, low alloy steel containing carbonitride-forming vanadium as precipitation hardening element. A novel hot rolled armor plate consists of a steel of composition (by wt.) 0.15-0.20% C, 0.10-0.50% Si, 0.70-1.70% Mn, less than 0.02% P, less than 0.005% S, less than 0.01% N, 0.009-0.10% Al, 0.50-1.00% Cr, 0.20-0.70% Mo, 1.00-2.50% Ni, 0.05-0.25% V, balan Fe and impurities. An Independent claim is also included for production of the above armor plate by hot rolling, double austenitizing at 880-980 degrees C, quenching and tempering at 150-550 degrees C.
Patent ES-2193913-T3 (ES)
Inventor: MASIP JOSEP-MARIA
IPC: A47J43/08
Filed: 2000-07-28
Granted: 2003-11-16
Abstract: The invention is directed to an electric powered hand mixer for processing food materials, which is provided with switching arrangements adjustably disposed on a housing (2) and featuring different settings for activation of a continuous-on mode and a pulse mode. Provision is made for tool mounts for holding various tools including, for example, a mixing or kneading tool (3) or a puréeing wand. A lock release element (14) is provided for ejecting a tool held in one of the tool mounts. Provision is made for two switching devices (10, 12) one of which is associated with the activation of the continuous-on mode and one with the activation of the pulse mode. The two switching devices (10, 12) and the lock release element (14) are mechanically coupled to each other so that only one of the two switching devices (10, 12) is actuatable at a time.
Patent ES-2214234-T3 (ES)
Inventor: JAQUEMONT ERIC
IPC: F02N15/02
Filed: 2000-09-21
Granted: 2004-09-16
Abstract: The circumferential region(3) of the flywheel(1) in radial section has a form which corresponds to an enclosed re-entrant right angle which has a circumferential face(10) for attachment of the ring gear(2) on the flywheel and radial face(11) for the contact between the ring gear and flywheel. The inner circumferential face(12) of the ring gear in radial section has a complementary form which corresponds to a projecting right angle and mates with the circumferential face of the flywheel and which has a radial face(14) mating with that of the flywheel. During engine start the ring gear slightly deforms on account of the spacing of the mating faces, and the radial face of the ring gear can slightly slide along the radial face of the flywheel. An Independent claim is included for a flywheel which has a facility for lubricating the radial faces of every tooth on the ring gear.
Patent ES-2333771-T3 (ES)
Title: Disposicion para la recepcion de un soporte de datos dentro de un dispositivo de datos que comprende un soporte pivotante.
Inventor: BATTY RAOUL
IPC: B60R25/04
Filed: 2000-10-05
Granted: 2010-03-01
Abstract: Disposición (10), destinada a equipar a un vehículo automóvil, para el intercambio de datos entre un soporte de datos rígido (12), o semi-rígido, que contiene datos representativos de un usuario autorizado, y un dispositivo de intercambio de datos, comprendiendo la disposición una caja (14) en la cual el soporte de datos (12) se introduce manualmente en un alojamiento (16) en un soporte articulado (18) de dicha caja (14) donde ocupa una posición activa determinada, estando dicho soporte articulado (18) montado pivotante con respecto al cuerpo de la caja (14) alrededor de un eje (A1) dispuesto en un primer extremo longitudinal (36) del soporte articulado (18), entre una posición abierta de introducción o de extracción, en la cual un extremo abierto (36) es accesible, y una posición cerrada en la cual el extremo abierto está obturado por una porción de pared fija (86) enfrentada al cuerpo de la caja (14), caracterizada por el hecho de que dicha caja (14) comprende medios de control de abertura y de acerrojamiento en posición cerrada de dicho soporte articulado del tipo "push-push", es decir del tipo según el cual una primera presión sobre una parte del soporte articulado (18) permite cerrarlo, haciéndolo pivotar alrededor de su eje de articulación, hacía dicha posición cerrada en la cual es retenido y acerrojado, y según el cual, partiendo de dicha posición cerrada, una segunda presión, de nuevo en el sentido del cierre, permite el desacerrojamiento del soporte articulado (18) y su abertura.
Patent ES-2194709-T3 (ES)
Title: Procedimiento para preparar carbamatos de tetrahidrotiopiran-o-fluorados.
Inventor: GAGE JAMES R
IPC: A61P31/04
Filed: 2000-01-31
Granted: 2003-12-01
Abstract: Un compuesto de fórmula (IV) en la que Réster se selecciona de entre: (I) alquilo C1-C10 opcionalmente sustituido con fenilo o grupos alcoxi 1 a 3 C1-C3; (II) alquenilo C2-C5 opcionalmente sustituido con fenilo o cicloalquilo C3-C7; (III) fenilo opcionalmente sustituido con 1 a 3 C1-C3 grupos alquilo; o (IV) naftilo opcionalmente sustituido con 1 a 3 C1-C3 grupos alquilo.
Patent ES-2244427-T3 (ES)
Title: Metodo para neutralizar y/o regenerar baños de acido y planta que lleva a cabo este metodo.
Inventor: GARCIA FERNANDO H
IPC: C01B7/04
Filed: 2000-02-10
Granted: 2005-12-16
Abstract: Método para neutralizar y/o regenerar baños de ácido, que comprende las etapas de: - preparar una disolución de ácido con una concentración molar por litro de iones [H+] fijada entre 4 y 8, partiendo de un baño de ácido, comprendiendo dicho baño de ácido al menos un ácido elegido de entre HCl, H2SO4, H3PO4, HNO3; - proporcionar un óxido metálico elegido de entre los óxidos metálicos que pueden formar con los aniones contenidos en dichos baños de ácido al menos una de las siguientes oxisales: oxicloruro u oxisulfato u oxifosfato u oxinitrato del catión de dicho óxido metálico, siendo la masa de dicho óxido metálico al menos suficiente para hacer que los iones [H+] de dicha disolución reaccionen por completo; - neutralizar dicha disolución añadiéndole dicho óxido metálico, obteniéndose así una mezcla que contiene al menos una de dichas oxisales.