baber/WOPTO huggingface dataset:
Patent FI-914150-A0 (FI)
Inventor: DICKHART RAINER
IPC: C07K14/575
Filed: 1991-09-03
Abstract: A method for the purification of insulins and insulin derivatives by chromatography in aqueous buffered solvents which contain water-miscible organic solvents on lipophilically modified silica gel is described and entails the aqueous buffered solvents containing zwitterions or the pH of the solvent mixture being in the vicinity of the isoelectric point of the insulin or insulin derivative to be purified, and zwitterions being present.
Patent FI-925675-A0 (FI)
Inventor: ANTRANIKIAN GARABED
IPC: C12R1/01
Filed: 1992-12-14
Abstract: This invention is within the field of thermostable proteases. More specifically, the present invention relates to a thermostable protease from Thermobacteroides proteolyticus, to a process for the preparation of these enzymes, and to detergent compositions comprising these enzymes. The enzyme has a temperature optimum in the range of from 75 to 95 DEG  and a pH optimum in the range of from 6.5-10.0.
Patent FI-930994-A0 (FI)
Inventor: SPAHN KARL-HEINZ
IPC: E05B49/04
Filed: 1993-03-05
Abstract: The electronic lock cylinder comprises a housing (1) with a cylinder core (9) which is mounted rotatably therein and which can be blocked in the conventional way by a key (15) via mechanical tumblers (21). The lock cylinder and the key (15) are assigned electronic control circuits (45, 47) which can be inductively coupled via coupling coils (43, 49) for the transmission of coding information. The coupling coil (43) of the lock cylinder is combined, together with all electronic components present within the lock cylinder and with a mounting (51), to form a constructional unit which is attached removably to one end face of the lock cylinder. In this way, the mechanical components and the electronic components of the lock cylinder can be mounted separately from one another, and the electronic components can, if appropriate, be exchanged, without the mechanical part of the lock cylinder having to be exchanged. <IMAGE>
Patent FI-932421-A0 (FI)
Inventor: GUPTE ARUN RAJARAM
IPC: A61M13/00
Filed: 1993-05-27
Abstract: The invention relates to a propellant-free inhalation device with a supply of pulverized medical substance in a supply chamber, which has a rotatable dosing means with one or more dosing chambers to receive in one defined position the dose of the medical substance to be inhaled from the supply chamber and to discharge the dose in another position. The inhalation device further is provided with a mouthpiece for active inhalation and an air channel to distribute the dose discharged from the dosing chamber in the flow of breathing air.
Patent FI-945036-A0 (FI)
Inventor: MODENA GIOVANNA
IPC: A41B3/00
Filed: 1994-10-26
Abstract: PCT No. PCT/IT92/00107 Sec. 371 Date Oct. 6, 1994 Sec. 102(e) Date Oct. 6, 1994 PCT Filed Aug. 26, 1992 PCT Pub. No. WO93/22942 PCT Pub. Date Nov. 25, 1993A brassi+E,gra e+EE re in which each cup (1,2), connected to both an elastic band (4) and a respective shoulder strap (7,8), consists, in its lower and lateral parts, of a continuous band (3,3') made of low-stretch fabric.
Patent FI-971746-A0 (FI)
Inventor: ADAMS JULIAN
IPC: A61K38/00
Filed: 1997-04-23
Abstract: Disclosed herein are novel boronic ester and acid compounds, their synthesis and their uses.
Patent FI-973551-A0 (FI)
Inventor: ILVES ANTTI
IPC: C09K5/04
Filed: 1997-08-29
Abstract: The invention relates to a liquid for evaporative cooling, said liquid being particularly suitable to indirect evaporative cooling apparatus. The liquid comprises an aqueous solution of trimethyl glycine, preferably containing 5-35 wt. % trimethyl glycine or a derivative thereof, and 65-95 wt. % water.
Patent FI-980217-A0 (FI)
Inventor: HENRICSON KAJ
IPC: F28D7/10
Filed: 1998-01-30
Abstract: A method and an apparatus for heating or cooling material having poor thermal conductivity, especially medium-consistency fiber suspensions. The material is directed, substantially as a plug flow, at a velocity below 5 m/s (e.g. 0.1-1 m/s) through an apparatus formed by a flow channel provided with heat exchange surfaces. The flow of the material is throttled at a throttling point by a more than 30% reduction in the cross-sectional area of the channel. After throttling, the material is discharged from the throttling point in such a manner that another portion of the material contacts the heat exchange surfaces.
Patent AP-9801272-A0 (AP)
Title: Use of an antagonist of ppar-alpha and ppr-gamma for the treatment of syndrom X.
Inventor: SMITH STEPHEN ALISTAIR
IPC: G01N33/15
Filed: 1997-01-07
Abstract: A method for the treatment and/or prophylaxis of syndrome x in a human or non-human mammal, which method comprises the administration of an effective, non toxic and pharmaceutically effective amount of an agonist of ppar and ppar r, or a pharmaceutically acceptable derivative thereof, to a human ornon-human mammal in need of such treatment, and certain compounnd for use in such method.
Patent IL-63108-A0 (IL)
Title: Methods and compositions for preparing peptides
IPC: C07K1/02
Filed: 1981-06-16
Abstract: Solution phase methods and compositions for preparing H-ARG-X-Z-Y-TYR-R wherein X is LYS and Y is VAL or X and Y are both SAR, Z is ASP or GLU, and R is NH<sub>2</sub> or OH.
Patent IL-72863-A0 (IL)
Title: Synergistic sweetening compositions
IPC: A61K47/22
Filed: 1984-09-05
Abstract: Combination of 6-methyl-1,2,3-oxathiazin-4(3H)-one-2,2-dioxide (acesulfame) with 3-(L-aspartyl-D-alaninamido)-2,2,4,4-tetramethyhhietane masks the bitter taste of the oxathiazine and at the same time provides synergistic sweetness over a range of concentrations.
Patent IL-92463-A0 (IL)
Title: Quinoxaline compounds,their preparation and pharmaceutical compositions containing them
IPC: A61K31/495
Filed: 1989-11-27
Abstract: Heterocyclic dihydroxyquinoxaline compounds having the formula <CHEM>  wherein R<1> is hydroxy, alkoxy, aryloxy, aralkyloxy, cycloalkylalkoxy, cycloalkoxy, or acyloxy; and R<5>, R<6>, R<7> and R<8> independently are hydrogen, NO2, halogen, CN, SO2NR min R min , SO2R min , CF3, or OR min , wherein R min  is hydrogen or C1-4-alkyl. The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use. The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters, particularly the quisqualate receptors, and especially as neuroleptics.
Patent SE-8505350-A0 (SE)
Title: Anordning vid rörformig ljuddämpare
Inventor: HANSEN L F
IPC: F24F13/24
Filed: 1985-11-13
Abstract: Rorformad ljuddampare, speciellt avsedd for anvandning i ventilationskanaler, bestaende av en utvandig rorformad beballare eller kammare (1) med centralt inlopp (7) och utlopp (8), i vilken behallaren invandigt vid sin mantelyta (2) har ett ljuddampande mineralfibermaterial (11) anordnat pa ett sadant satt att det skapas en central kanal mellan inlopp och utlopp och dar mineralullsmaterialet in mot kanalen (9) ar forsett med ett av hl perforerat material (10). Ljuddampnings- materialet bestar av mineralfibrer som är anordnade radiellt i ljuddamparen och materialet har paforts en duk (13) med oppen struktur in mot kanalen (9). Duken (13) bestar foretradesvis.av icke flamspridande textilmaterial, och har Worts genom limning. Mineralfibermaterialet bestar i utgangslaget av en matta av mineralullfibrer dar fibrerna ar orienterade i en riktning tvars sidoytorna, vilken matta inlagts i kammaren pa ett sadant satt att de sammanfallande kanterna pressas mot varandra.
Patent FI-20001616-A0 (FI)
Inventor: SALMELA ARTTU
IPC: F23C15/00
Filed: 2000-07-06
Abstract: The invention concerns equipment and a method for enhancing the combustion event and heat transfer in a heating boiler. According to the invention, the space above the major combustion zone in the combustion space of the heating boiler is equipped with sound sources, which are used to generate an acoustic field to enhance the combustion event and to achieve more complete combustion.
Patent FI-20115267-A0 (FI)
Inventor: HONKANEN JARNO
IPC: B65G/
Filed: 2011-03-18
Abstract: The objective of the invention is to create an overhead robot system that reduces the movements of the system's gripper when it is desired to pick up an individual object from the middle of a stack of objects. The number of movements is reduced as the gripper can be driven to above the desired stack of objects and does not need to be subsequently moved to another location above the warehouse area in order to pick up and move a single object. The invention comprises a separate arrangement for moving a single picked-up object to the edge of the warehouse area. The gripper can move more quickly to the next object to be picked up.
Patent IL-106504-A0 (IL)
Title: Chlorination process
IPC: C07C19/08
Filed: 1993-07-28
Abstract: A process for the preparation of 1,1,1-trichlorotrifluoroethane in which 1-chloro-2,2,2-trifluoroethane is subjected to chlorination by bringing the 1-chloro-2,2,2-trifluoroethane into contact with chlorine within a reaction vessel characterized in that the process is conducted in the liquid phase in the presence of a chemical free radical initiator under a pressure of from 1 to 20 bar and at a temperature within the range 50 DEG  to 120 DEG  C., and the product is separated from the reaction mixture by fractional distillation.
Patent IL-116394-A0 (IL)
Title: Method for producing containers such as bottles or the like with film of thermoplastic synthetic material and apparatus for carrying out the method
IPC: B29C49/64
Filed: 1995-12-14
Abstract: A method for producing containers, such as bottles or the like, with a film made of thermoplastic synthetic material, and to an apparatus for performing the method. The process comprises: a step for thermally bonding two strips (3a, 3b) of film made of thermoplastic synthetic material that face one another, so as to form, between the two strips of film, pouches (12) that are open at a longitudinal edge of the strips of film; and a thermoforming step, during which a segment of the two strips (3a, 3b) of film, in which the pouches (12) are formed, is inserted in a forming mold (21a, 21b) that is provided with molding cavities (22) located at the pouches (12), and a pressurized fluid is injected into the pouches (12) through their open side to form them, by plastic inflation, inside the molding cavities (22). The thermal bonding of the two strips (3a, 3b) of film that form the pouches (12) is correlated to the dimensions of the molding cavities (22), so that the thermal bonding line, which delimits the pouches (12), lies inside the corresponding molding cavity (22) at a preset distance from the walls of the molding cavity (22) when the strips of film are inserted in the forming mold (21a, 21b). The thermoforming step is followed by a step for blanking at least the portions of the strips of film that protrude from the base and from the lateral surface of the contour of the containers (30) that are thermoformed at the pouches (12). <IMAGE>
Patent IL-117083-A0 (IL)
Title: Pyridine and pyridazine derivatives processes for the production thereof and pharmaceutical agents containing these compounds
IPC: A61K31/4427
Filed: 1996-02-08
Abstract: PCT No. PCT/EP96/00523 Sec. 371 Date Aug. 11, 1997 Sec. 102(e) Date Aug. 11, 1997 PCT Filed Feb. 8, 1996 PCT Pub. No. WO96/24586 PCT Pub. Date Aug. 15, 1996Compounds of Formula I    <IMAGE>  (I)  in which the variables are defined herein, processes for the production thereof as well as pharmaceutical agents containing these compounds for the treatment of diseases which are the result of thromboembolytic events.
Patent IL-142824-A0 (IL)
Title: Lipoic acid derivatives and their use in treatment of disease
IPC: A61K31/265
Filed: 1999-10-26
Abstract: The invention provides a method of inhibiting proliferation of diseased cells by contacting the diseased cells with an effective amount of a reagent that inhibits PDC specifically in said diseased cells.
Patent IL-145457-A0 (IL)
Title: Hydrophilic macromolecular compounds
IPC: C08F216/06
Filed: 2000-03-16
Abstract: The invention relates to macromolecular hydrophilic photocrosslinkers having polymeric backbones of substituted ethylene groups carrying photoactive groups. The photocrosslinkers are capable of producing, when being exposed to light of determined wavelengths above 305 nm, radicals which are retained on the macromolecular photocrosslinkers and reacting so as to accomplish a crosslinked network structure. The invention further relates to the preparation of photocrosslinkers, their use in different aqueous systems and their utility in production of medical devices including ophthalmic lenses.
Patent IL-150698-A0 (IL)
Title: Processes for preparing clarithromycin polymorphs
IPC: A61K31/7048
Filed: 2000-12-15
Abstract: The present invention relates to processes for converting clarithromycin Form I to clarithromycin Form II, which include slurrying clarithromycin the Form I in water. The present invention also relates to processes for the preparation of clarithromycin Form II by converting erythromycin A to clarithromycin and thereafter converting clarithromycin Form I to clarithromycin Form II by slurrying.
Patent IL-155319-A0 (IL)
Title: An azide method and composition for controlling deleterious organisms
IPC: A01N25/02
Filed: 2001-10-09
Abstract: Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising an azide and an azide stabilizer. The azide can be selected from the group consisting of sodium azide and potassium azide or a combination of the two. The composition provides an effective pesticide, without causing significant harm to the environment. The composition may be applied to soil to control a population of a deleterious organism.
Patent IL-176532-A0 (IL)
Title: A process and capsule for preparing beverages
IPC: B65D81/00
Filed: 2006-06-25
Abstract: A single serve capsule (1) for the preparation of hot beverages such as coffee, cappuccino, tea or the like from soluble or ground preparations, having an outlet lid portion (1 b) located on a dispensing wall (F) in order to form a dispensing opening (11) after a liquid has been introduced into the capsule, as well as means for changing the area of said dispensing opening during the dispensing step of the beverage.
Patent IL-178400-A0 (IL)
Title: Compounds for proteasome enzyme inhibition
IPC: C07K5/087
Filed: 2006-09-28
Abstract: Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.
Patent IL-185101-A0 (IL)
Title: Poly-epitope peptide derived from thymidylate synthase having immunological and anti-tumour activity
IPC: A61P35/00
Filed: 2007-08-07
Abstract: The present invention concerns a peptide having anti-tumour activity and its related pharmaceutical compositions. In particular, the invention concerns a peptide with anti-tumour preventive and therapeutic activity, also in combination with other known anti-tumour compounds such as, for example, 5-fluorouracil.
Patent IL-193544-A0 (IL)
Title: Sprung anti-backing-off device
Filed: 2008-08-19
Abstract: The invention relates to a mechanical sprung anti-backoff device, capable of fixedly immobilizing or releasing a manual control handwheel (4) and a motor acting on one and the same rotation shaft, comprising a cylindrical spring (7, 16), a cylinder (9, 17) mounted so as to rotate on the rotation shaft, the spring being able to rotate with the cylinder, turns of the spring being in contact with a surface of the cylinder and its ends being capable of coming into contact with the handwheel. The ends of the spring (7, 16) are curved inward or outward, the handwheel (4) may act on the curve of one or other of the ends of the spring (7, 16), and the rotation of the spring (7, 16) is limited by a stop acting against one or other of the ends of the spring. Application can be to manual control and motorized control valves, for example on fluid pipes.
Patent RO-131139-A0 (RO)
Title: Helical wind turbine
Inventor: RUSU CONSTANTIN
IPC: F03D9/11
Filed: 2015-12-14
Abstract: The invention relates to a wind turbine with vertical axle, with helical profile, meant to fit out wind power stations of low, medium and high power located in urban areas, and also in areas where the placement of turbines with horizontal axle is forbidden, such as the routes of migratory birds. According to the invention, the turbine consists of a quasi-cylindrical body, horizontally limited, at its top and bottom, by two identical flat covers in the shape of a four-pointed star, with curvilinear sides, in a non-symmetrical S-like shape, the covers being mounted on a vertical axle, and vertically limited, by four identical spatial surfaces resulting from the vertical translation of the star-like cover plane simultaneously with the horizontal rotation thereof, so as to result in a rotation of 90° between the top and bottom covers.
Patent RO-134882-A0 (RO)
Title: Phytotherapeutic composition for preventing and treating diabetes mellitus and process for preparing the same
Inventor: PUSTA DANA-LIANA
IPC: A61K36/46
Filed: 2020-10-19
Abstract: The invention relates to a phytopharmaceutical composition for the prevention and treatment of diabetes mellitus and to a process for preparing it. According to the invention, the composition consists, in mass percentage, of 44% natural concentrate of blueberries (Vaccinium myrtillus L), in powder form, 3% natural concentrate of sea buckthorn fruits (Hippophae rhamnoides L), 50% fillers such as dextrose, starch, lactose and gelatin and 3% anti-caking agents such as talcum and magnesium stearate. The claimed process consists in the steps of processing the blueberries by pressing and filtering, preserving the liquid part with dextrose in equal parts, and drying the solid part for 48...60 h, up to a humidity of 10...12%, preserving the chopped sea buckthorn fruits by mixing with dextrose in equal parts, proportional mixing of the liquid part of the blueberries with the solid part of preserved blueberry and sea buckthorn fruits, crushing and granulating the concentrate with fillers, followed by drying and granulation, in the presence of anti-caking agents, resulting in a natural concentrate in the form of tablets of 1.00 g with hypoglycaemic action, with effects of regeneration of pancreatic β cells and with effects in ocular and renal changes induced by diabetes.
Patent RO-135475-A0 (RO)
Title: Process for producing eco-sustainable masonry blocks named "caloriblock", with high thermal performance, for constructions, made by recycling wooden material
Inventor: ENŢUC IOANA-SORINA
IPC: E04B2/02
Filed: 2021-09-03
Abstract: The invention relates to a process for producing eco-sustainable masonry blocks with high thermal performance for constructions, named "caloriblock" made by recycling wooden material, which ensures the extrusion of elements by means of gravitational force, without the need to use special equipment for ensuring the pressure of the material at the top (19), the material being passed through a series of metal moulds (1), these being the ones that will generate the desired geometric shape, and, in order to eliminate formworks, the material must have an appropriate consistency, the recipe containing wood chips with a maximum size of 25 mm, cement with a weight equal to that of the wooden material and water, in a percentage of 15...19% of the amount of cement.
Patent MA-22343-A1 (MA)
Inventor: J R ANDRE
IPC: A23G3/00
Filed: 1991-11-15
Abstract: The present invention relates to marzipan-like compositions comprising psyllium fiber and almond paste, and the use of these compositions as laxatives and/or for cholesterol reduction benefits. The compositions are a convenient, portable, highly palatable, and well tolerated dosage form for administering psyllium fiber.
Patent MA-24904-A1 (MA)
Title: Procede de preparation d'intermediaires pesticides
Inventor: ANCEL JEAN-ERICK
IPC: C07C253/30
Filed: 1999-04-20
Abstract: L'INVENTION CONCERNE UN PROCÉDÉ DE PRÉPARATION DE COMPOSÉS DE FORMULE (1)  :DANS LAQUELLE R1,  R2  ET  W SONT TELS QUE DÉFINIS DANS LA DESCRIPTION
Patent MA-27518-A1 (MA)
Title: Nouveau procede de synthese et nouvelle forme cristalline de l'agomelatine ainsi que les compositions pharmaceutiques qui la contiennent
Inventor: GONZALEZ BLANCO ISAAC
IPC: A61P25/16
Filed: 2005-02-11
Abstract: NOUVEAU PROCEDE DE SYNTHESE ET NOUVELLE FORME CRISTALLINE DE L'AGOMELATINE AINSI QUE LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT Procédé de synthèse industrielle et forme cristalline II du composé de formule (I) Médicaments
Patent MA-38827-A1 (MA)
Title: Combinaison d'un inhibiteur de mek et d'un inhibiteur d'erk pour l'utilisation dans le traitement de maladies hyperprolifératives
Inventor: BELVIN MARCIA
IPC: A61P35/00
Filed: 2014-09-04
Abstract: L'invention concerne des combinaisons comprenant un inhibiteur de mek (comme gdc-0973 ou gdc-0623) ou d'un sel pharmaceutiquement acceptable de celui-ci et d'un inhibiteur d'erk (comme gdc-0994). Les combinaisons sont particulièrement utiles pour traiter des troubles hyperprolifératifs, tels que le cancer.
Patent MA-39088-A1 (MA)
Title: Compositions et procédés pour moduler des récepteurs farnesoïde x
Inventor: MOLTENI VALENTINA
IPC: C07D491/052
Filed: 2014-11-04
Abstract: L'invention concerne des composés de formule i, un stéréoisomère, un énantiomère, un sel pharmaceutiquement acceptable ou un acide aminé conjugué de celui-ci, des variables telles que définies dans la description, et leurs compositions pharmaceutiques, qui sont utiles en tant que modulateurs de l'activité de récepteurs farnesoïde x (fxr).
Patent MA-42359-A1 (MA)
Title: Appareils et procédés de production de couches à effet optique comprenant des particules de pigment magnétiques ou magnétisables non sphériques orientées
Inventor: DESPLAND CLAUDE-ALAIN
IPC: B42D25/00
Filed: 2016-09-07
Abstract: La présente invention concerne le domaine des assemblages magnétiques et des procédés permettant de produire des couches à effet optique (oel) comprenant des particules de pigment magnétiques ou magnétisables non sphériques orientées magnétiquement sur un substrat. En particulier, la présente invention concerne des assemblages magnétiques et des procédés permettant de produire lesdites oel en tant que moyen anti-contrefaçon sur des documents de sécurité ou des articles de sécurité ou à des fins décorative
Patent MA-47221-A1 (MA)
Title: Anticorps monoclonal à pd-l1
Inventor: ANDREI BORISOVICH
IPC: C12N15/13
Filed: 2018-04-11
Abstract: L'invention concerne le domaine de la biotechnologie et propose des anticorps qui se lient spécifiquement à pd-l1. L'invention concerne des adn qui codent pour lesdits anticorps, qui correspondent aux vecteurs d'expression, et des procédés de production ainsi que des méthodes de traitement utilisant ces anticorps.
Patent UY-24699-A1 (UY)
Title: Derivados de n- bencilazolio
Inventor: ICHIHARA SHIGEYASU
IPC: A01N43/647
Filed: 1997-09-08
Abstract: Los derivados del n-bencilazolio, de fórmula general (i), en donde q es el resto de un compuesto azolico de formula ii que posee actividad antifúngica; z es nitrógeno o metino; r1 y r2 son cada uno independientemente entre sí, un átomo de hidrógeno o un grupo -oy(en el cual y es un grupo facilmente hidrolizable en condiciones fisiológicas); r3 y r4 son cada uno independientemente entre si, un átomo de hidrógeno o halógeno, alquilo inferior, alcoxilo inferior, alquiltio inferior, (alquilcarbonilo inferior) tiometilo, carboxilo o metoxicarbonilo; y x es un anión farmacéuticamente aceptable, así como las sales