baber/WOPTO huggingface dataset:
Patent DE-112019000371-B4 (DE)
Title: Verfahren zum Screening psychoaktiver Substanzen unter Verwendung eines NMR-Spektrometers, welches einen Permanentmagneten aufweist
Inventor: WILLIAMSON DAVID
IPC: G01N24/08
Filed: 2019-01-10
Granted: 2023-05-11
Abstract: Verfahren zum Screening einer Probe aufweisend eine Testverbindung auf psychoaktive Substanzen, wobei das Verfahren ein Bereitstellen eines Auftisch-NMR-Spektrometers mit einem Permanentmagneten mit einer magnetischen Feldstärke von 0,5 Tesla bis 2,5 Tesla und ein Ausführen eines Computerprogramms zur Durchführung nachfolgender Schritte aufweist:(a) Erhalten eines NMR-Spektrums der Probe unter Verwendung des Auftisch-NMR-Spektrometers, und Erzeugen eines Messspektrumsatzes unter Verwendung des NMR-Spektrums, wobei der Messspektrumsatz aus einem oder mehreren verschobenen Spektren besteht, wobei jedes verschobene Spektrum mit einem NMR-Spektrum bei einer unterschiedlichen Frequenzverschiebung korrespondiert;(b) Vergleichen des Messspektrumsatzes mit einem oder mehreren Referenzspektren, wobei sich jedes Referenzspektrum auf eine psychoaktive Substanz bezieht und mittels einer magnetischen Feldstärke von 0,5 Tesla bis 2,5 Tesla erfasst wurde; und(c) Kategorisieren der Testverbindung in eine Klasse psychoaktiver Substanzen basierend auf dem Vergleich.
Patent DD-217251-B5 (DD)
Inventor: MEMMINGER GUSTAV
IPC: D04B15/50
Filed: 1983-09-05
Abstract: To permit pull-off of elastomeric yarn from a spool, without subjecting the yarn to tension, the spool (6) with the yarn (17) wound thereon is placed on a pair of horizontally extending support-and-drive rollers (3) which are driven at pull-off speed by a belt drive (7, 8, 10) from the textile machine via a right-angled drive (FIG. 3) from a drive pulley (11). The drive is reversible. The yarn is fed by frictional engagement of the yarn portion being pulled off the spool with a portion of the circumference of the driven support-and-drive rollers (3) and, if the weight of the spool is not sufficient to provide for suitable frictional engagement, the surfaces of the rollers can have knurling or a rubber coating thereon; they may be spring-loaded or weighted. Additional drive can be obtained by looping an endless belt (24) about the rollers, and seating the spool (6) in a concave depression formed by the belt as the spool is positioned between the support-and-drive rollers. The holder has a standard U-clamp to fit on the yarn supply holder ring of a circular knitting machine.
Patent CZ-280864-B6 (CZ)
Inventor: KREITMEIER LEONHARD DR
IPC: H04R9/06
Filed: 1992-05-15
Abstract: Pro oddělení oblasti s hlubokými tóny od  oblasti se střední výškou tónů v reproduktorové  skříni osazené střednětónovým reproduktorem  (10) a hloubkovým reproduktorem je  střednětónový reproduktor (10) opatřen plně  uzavřenou reproduktorovou klecí (14) a jeho  vnitřní prostor (25) mezi membránou (15) a  reproduktorovou klecí (14) je spojen s výstupním  prostorem (26), do kterého má být vyzařován  akustický tlak střednětónového reproduktoru  (10), průtokovými kanálky (24), vytvořenými v  obvodovém okraji (17) reproduktorové klece (14).  Spojením vnitřního prostoru (25) prostřednictvím  průtokových kanálků (24) s výstupním prostorem  (26) se podstatně snižují vlastní rezonance  střednětónového reproduktoru (10) s plně  uzavřenou reproduktorovou klecí (14).ŕ
Patent CS-276949-B6 (CS)
Inventor: HUDEK LUBOMIR ING
IPC: B65G49/06
Filed: 1990-07-18
Abstract: Zakladaó /1/ zařízení sestává ze základového rámu /2/ s pevným středovým sloupkem /3/, na němž je suvně uchycena základová zdvihová deska /4/ s mechanismem /5/ otáčení otočného nosiče /6/. Na otočném nosiči /6/ jsou připevněna vzájemně na sebe kolmá, mimoběžná a výsuvná vkládací a vyjímací ramena /7,8/ nesoucí vkládací a vyjímací kleštiny /9,10/ s čely /31/. Vzájemné předáváni skleněných trubic /11/ a hotových skleněných výrobků /12/ zajištují tato výsuvná ramena /7,8/ s kleštinami /9,10/ prostřednictvím mechanismu /5/ otáčení a zdvihového pohybu základové zdvihové desky /4/ po pevném středovém sloupku /3/. Pro tyto účely je umístění upínacího mechanismu /13/ upínacího sklíčidla /20/, podávaciho dopravníku /26/ a odebiraciho dopravníku /33/ na základovém rámu /2/ zařízeni.
Patent CZ-279249-B6 (CZ)
Title: Securing of pins
Inventor: HAISMAN JAROSLAV
IPC: F16B1/00
Filed: 1989-06-15
Abstract: In the head (4) of the body (5) of the box there is a hollow securing bolt (1), running through whose continuous longitudinal hole and its coaxial cross hole in the securing pin (3) is a dowel (2).<IMAGE>
Patent CZ-298612-B6 (CZ)
Title: Inhibitor of endothelium cell proliferation and the use thereof
Inventor: CAO YIHAI
IPC: C12N15/09
Filed: 1996-12-13
Abstract: The present invention relates to a method of in vitro inhibiting endothelial cell proliferation, comprising administering to an endothelial cell an effective amount of a protein having an amino acid sequence encoding a Kringle 5 peptide of a plasminogen molecule, further to the use of such protein for preparing a medicament, corresponding pharmaceutical composition.
Patent CZ-297254-B6 (CZ)
Title: Resonant multi-mode radiator element and panel-form loudspeaker
Inventor: HERON KENNETH HARRY
IPC: H04R1/00
Filed: 1997-12-08
Abstract: In order to overcome acoustic distortion caused by local resonance in panel core cells, a resonant multi-mode radiator element is developed for a panel form loudspeaker with a functional upper frequency limit fimax. The element has two skins and a cellular based core, the skins have a thickness h, a Young's modulus E a Poisson's ratio of V and a material density rho, and the core has a cell size licell characterized in that the cell size licell is less than (I).
Patent CZ-299793-B6 (CZ)
Title: Aqueous suspension of mineral materials and its use
Inventor: BLUM RENU VINZENZ
IPC: C09K23/00
Filed: 1998-07-16
Abstract: Aqueous suspension of mineral materials contains copolymer as dispersion agent and/or to help crush the materials. The copolymer consists of: (a) at least one ethylenically unsaturated monomer with carboxylic group selected from monoacids e.g. (meth)acrylic, (iso)crotonic, and cinnamic; diacids e.g. fumaric and maleic; acid anhydrides such as maleic anhydride; and diacid hemiesters such as 1-4c monoesters of maleic acid; (b) optionally at least one unsaturated monomer with a sulphonic group e.g. sodium methallylsulphonate or styrene sulphonic acid; or a phosphoric group e.g. propylene glycol (meth)acrylate phosphate; (c) optionally at least one unsaturated monomer without a carboxylic group e.g.; (meth)acrylic esters, (meth)acrylonitrile, styrene, (meth)acrylamide; and (d) at least one unsaturated oxyalkyl monomer with terminal hydrophobic chain of general formula R-((CHi2-CH(Ri1)-O)m-CHi2-CHi2-O)in-(CHi2-CH(Ri2)ip)iq-R'. In the formula, m, n, p <= 100; q is number such that 0 <= q x (n + m + p) <= 100; Ri1, Ri2 = H, methyl, or ethyl; R = polymerizable unsaturated radical belonging to group of esters including (meth)acrylic, crotonic and vinylphthalic, as well as unsaturated urethanes such as (meth)acrylurethane, or allylurethane; and R' = hydrophobic radical such as tristyrylphenyl,, or 8-30C alkyl, aryl, alkylaryl, arylalkyl, or, when R = urethane, 8C dialkyl, or, better, when R = unsaturated polymerizable radical, >= 22C dialkyl amine; total of a + b + c + d = 100 pts. The suspension has specific viscosity no greater than 25. Also claimed is the use of the suspension in paper industry, in particular as sizing agent for paper.
Patent CZ-290512-B6 (CZ)
Title: Method for setting internal combustion engine idle run and apparatus for making the same
Inventor: NUSSER CLAUS DIETER ING
IPC: F02D41/08
Filed: 1995-09-18
Abstract: Disclosed is a method for setting internal combustion engine idle run where at hot the idling speed increases. The method is characterized by determining operation state of a hot internal combustion engine in dependence on both the engine speed and engine load. The apparatus for making the method comprises means for determining operation state of a hot internal combustion engine in dependence on at least engine speed and engine load.
Patent CZ-297892-B6 (CZ)
Title: Yarn take-off nozzle
Inventor: SCHLOEMER BERT
IPC: D01H4/40
Filed: 1998-08-26
Abstract: In the present invention, there is disclosed a yarn take-off nozzle of a rotor spinning apparatus having a spiral surface structure (30), where in the contact region with the thread (26) it has an additional notch structure consisting of notches (34). The notches (34) are placed at the funnel-shaped entry into the yarn take-off channel (21) and after the spiral surface structure (30) in the direction of the thread (26) take-off.
Patent CZ-283866-B6 (CZ)
Title: Set for welding plastic made pipe systems
Inventor: LIPUS PAVEL ING
IPC: B23K37/00
Filed: 1994-11-08
Abstract: The set for welding plastic pipe systems contains a frame (1) with fixed grips (2), on which a conduit (4) is formed, parallel to the longitudinal axis (21) of the fixed grips (2), fitted with a sliding moving grip (5), which is interconnected with the drive sections of a linear motion mechanism (6). The given drive section is fitted axially and adjustably and interconnected with the drive, control apparatus and measurement apparatus (7) for measurement of the reaction (R) of welding forces (F).<IMAGE>
Patent CZ-292549-B6 (CZ)
Title: Process for preparing HIV protease inhibitor
Inventor: ASKIN DAVID
IPC: C07D401/06
Filed: 1996-03-11
Abstract: The invented process for preparing HIV protease inhibitor i.e. the compound J is characterized by the following steps: heating for at least one hour a mixture of one equivalent of (S)-4-(3-picolyl)-2-tert-butyl carboxamide piperazine of the general formula 1 with about one equivalent of the compound of the general formula 2 at a temperature range between about 25 to about 150 degC, whereby said mixture optionally containing suitable solvent; deblocking by treatment with strong acid the protecting group from the obtained compound of the general formula 3 and; neutralizing the mixture, to give the desired product.
Patent CZ-290129-B6 (CZ)
Title: Hydraulic pump
Inventor: BRUNNER RUDOLF
IPC: F04B1/0413
Filed: 1998-09-21
Abstract: In the present invention there is disclosed a hydraulic pump (P) comprising at least one axial piston element of the pump (P), which piston (11) is oriented toward an eccentric (E) of a driving shaft (2), and an eccentric sliding bearing  (G) that is formed by a bearing bush (B) secured in a bearing ring (R), and which is arranged between the eccentric (E) and the bearing ring (R), which is rotatably mounted on the eccentric (E). The bearing bush (B) and the bearing ring (R) are provided with pressed out a locally engaging stop elements (A1, A2) securing the bearing bush (B) in the bearing ring (R) in both rotary and axial directions.
Patent CZ-292255-B6 (CZ)
Title: Substituted 1-phenylpyrazole-3-carboxamides, process of their preparation, intermediates for such preparation and pharmaceutical composition in which the carboxamides are comprised
Inventor: LABEEUW BERNARD
IPC: C07D231/12
Filed: 1996-04-11
Abstract: The present invention relates to novel substituted 1-phenylpyrazole-3-carboxamides of the general formula  Ia, which exhibits affinity to neurotensin receptors, further process of their preparation, intermediates for such preparation and pharmaceutical compositions in which the carboxamides are comprised as active substance.
Patent SK-281961-B6 (SK)
Inventor: BUYSCH HANS-JOSEF
IPC: B01J23/46
Filed: 1997-08-20
Abstract: Riešenie sa týka spôsobu výroby karbazolu dehydrogenáciou zlúčenín vzorcov (I), (II) a (III), prípadne aminačnou dehydrogenáciou zlúčenín vzorcov (IV), (IVa), (V), (VI), (VII), (VIII), (IX) a (X) za prítomnosti irídiových katalyzátorov alebo irídium obsahujúcich katalyzátorov na nosičoch pri teplote v rozmedzí 300 °C až 600 °C za prítomnosti vodíka.ŕ
Patent SK-284317-B6 (SK)
Title: Semisolid pharmaceutical formulation containing dexketoprofen trometamol
Inventor: MAULEON CASELLAS DAVID
IPC: A61P29/00
Filed: 1998-06-04
Abstract: The present invention relates to a process for the preparation of a semisolid pharmaceutical formulation (gel or cream) containing dexketoprofen trometamol and different amines as neutralizing agents, for the topical treatment of inflammatory processes in humans. The pharmaceutical formulations object of the present invention show advantages deriving from their high storage stability without noticeable changes in the appearance of the product in time, as well as from their lower allergenic and photoallergenic activities.
Patent SK-278577-B6 (SK)
Title: Use of 6-(2-(4-(bis(4-fluorophenyl)methylene)-1- -piperidinyl)ethyl)-7-methyl-5h-thiazolo£3,2-a|pyrimidin-5-one
Inventor: MEERT THEO FRANS
IPC: A61P25/30
Filed: 1991-06-11
Abstract: This patent describes a utilisation of 6-(2-4-(bis(4- -fluorophenyl)methylene-1-piperidinyl)ethyl)-7-methyl-5H- -thiazolo£3,2-a|pyrimidin-5-one with a general formula (I) or the additive salts with acid, suitable from pharmaceutical point of view, being able to lower, suppress or overcome the dependence of the habituate drugs and to damp the symptoms related to the interruption of using drugs or any other symptoms closed to the abstention of using drugs.
Patent SK-282056-B6 (SK)
Title: Method of improving the organoleptic qualities of meat from non-castrated male domestic animals
Inventor: DUFOUR RAYMOND
IPC: C07K16/00
Filed: 1992-02-26
Abstract: The process for improving the organoleptic qualities, in particular the odour, savour and tenderness, of meat from non-castrated male domestic animals comprises, shortly before slaughtering the animal concerned, the suppression of the action of androgenic and nonandrogenic steriods by active or passive anti-LHRH immunoneutralisation while maintaining, and up to slaughtering, the advantages linked to the male characteristics of the animal. The vaccines comprise, as peptide, natural LHRH or a peptide of formula Trp - Ser - Tyr - Gly - Leu - Arg - Pro - Gly - NH2, coupled to an immunogenic carrier protein.
Patent CZ-305837-B6 (CZ)
Title: (3{alpha}, 5{beta},20S)-3-Nitrooxy-pregnane-20-carboxylic acid
Inventor: DRAŠAR PAVEL
IPC: C07J75/00
Filed: 2015-02-25
Abstract: In the present invention, there is disclosed (3{alpha}, 5{beta},20S)-3-nitrooxy-pregnane-20-carboxylic acid of the general formula 1.
Patent CZ-307514-B6 (CZ)
Title: A holder of a brush of an electric machine
Inventor: VESELKA FRANTIŠEK
IPC: H02K13/02
Filed: 2015-12-01
Abstract: The invention relates to a holder of a brush of an electric machine which is in the shape of a cylinder provided with helical winding and the inner space of the cylinder is provided with partitions. The winding has a cross-section of an n-angle shape, where n is 3 to 12, or it has a circular cross-section. The partitions of the inner space are preferably in the form of a hyperboloid.
Patent CZ-307652-B6 (CZ)
Title: Způsob biodegradace farmaceuticky aktivních látek na bázi sulfonamidů v odpadní nebo v povrchové vodě, směsný celobuněčný katalyzátor
Inventor: FILIŠTEIN VÁCLAV
IPC: C02F101/38
Filed: 2017-12-21
Abstract: Biodegradace farmaceuticky aktivních látek na bázi sulfonamidů, zejména sulfamethoxazolu a/nebo sulfathiazolu, v odpadní vodě v čistírnách odpadních vod nebo v povrchové vodě probíhá použitím směsi bakteriálních kmenů, které se do odpadní vody přidají ve formě metabolicky aktivní směsné kultury bakteriálních kmenůsp. asp. v poměru kmenů v rozmezí 1:4 až 4:1 v množství 0,01 až 20 hmotnostních % vlhké hmotnosti v živném médiu. Tato kombinace bakteriálních kmenů poskytuje schopnost účinně biodegradovat rozpuštěné perzistentní polutanty na bázi sulfonamidů, jejichž přítomnost v odpadní vodě způsobuje trvalé následky pro životní prostředí.
Patent CZ-309243-B6 (CZ)
Title: Picking up seedlings and tree sprouts for mechanized planting
Inventor: STRAŠÁK ST MILAN
IPC: A01G23/04
Filed: 2020-12-16
Abstract: A tree (and) pick-up (1) comprising a frame (2) for connection in front of or behind the vehicle, which comprises a control mechanism (3) which consists of a fixed part (4) and a rotating part (5). Rollers (A) are arranged between the fixed part (4) and the rotating part (5). Both parts (4), (5) are open at the front and the rotating part (5) comprises a central cylinder (25) and on the rotating parts (5) they can pivot opposite each other via the inner hinges (12) and outer hinges (13) on the pins of hemispherical spades (11) have interlocking teeth (22)at the bottom. At the upper edge of the spade (11) facing the frame (2), the spades (11) have lever protrusions (26), at the ends of which the anchors (15) of the piston rods (10) of the vertical cylinders (9) mounted in the anchors (14) are made on rotating parts (5). Driving devices (B) are arranged between the fixed part (4) and the movable part (5).
Patent CZ-302888-B6 (CZ)
Title: Pharmaceutical composition for oral administration comprising rivastigmine and use of rivastigmine
Inventor: OGORKA JOERG
IPC: A61K47/38
Filed: 1999-10-01
Abstract: The present invention relates to a pharmaceutical composition for peroral administration comprising rivastigmine and having the following release characteristics in water: time (minutes) amount (percentage): 30, 1 to 40; 60, 10 to 60; 120, 40 to 80; 180, 60 to 90; 240, 65 to 95; 300, 70 to 99; 360, 75 to 99; 420 more than 80. The invention also relates to the use of rivastigmine in the manufacture of a medicament for the treatment of patients with mild to moderately severe dementia of the Alzheimer's type.
Patent CZ-292686-B6 (CZ)
Title: Measuring method of basophile activation after stimulation with allergen for determining allergy to the allergen and corresponding kit therefor
Inventor: HAVRANOVA MARIE ING
IPC: G01N33/53
Filed: 2001-09-17
Abstract: The invented method for measuring basophile activation after stimulation with allergen for determining allergy to this allergen is characterized in that a blood sample, in which interleukin-3 has been added in an amount of 0.05 to 5?ng/ml, based on the sample volume, and a corresponding diluted allergen in an amount of 0.5 to 100 units/ml, is incubated for a period of 15 to 45 minutes at a temperature corresponding to a physiological medium, whereupon a labeled antibody anti-CD63 and a labeled antibody against a basophile surface sign are added therein at a temperature ranging from 0 to +10 degC and both in the amount of 3 to 30 microliter /100 microliter of blood, the sample is stirred and incubated for a period of 15 to 30 minutes in an ice bath. Subsequently the sample is subjected to lyophilization and then to flow cytometry. The present invention also relates to a kit for determining allergy to allergens, whereby the kit comprises per 100 tests 1 ng to 1 microgram interleukin-3, 200 ml buffer, 0.3 to 3 ml of labeled antibody anti-CD63 and 0.3 to 3 ml of labeled antibody against basophile surface sign, 4.33 microgram of N-formyl-L-methionyl-L-leucyl-L-phenyl alanine and optionally other vehicles.
Patent CZ-305120-B6 (CZ)
Title: Process for preparing collagen sponge
Inventor: SCHAUFLER ALFRED
IPC: C08J9/30
Filed: 2002-01-25
Abstract: In the present invention, there is disclosed a process for preparing collagen sponge, said preparation process comprising the following steps of: preparation of a collagenous gel; mixing air into the collagenous gel to obtain collagenous foam; drying the collagenous foam in order to obtain a dry block of a collagen sponge of a three-dimensional structure with arranged chambers, which are separated and substantially completely surrounded by wall of the collagenous material; and separation of parts of the sponge with a chamber diameter greater than 0.75 mm and less than 4 mm or with average diameter of 3 mm at the most from the collagen sponge block.
Patent CZ-301203-B6 (CZ)
Title: Medicament for prevention or treatment of neurodegenerative disorders
Inventor: PLATA-SALAMAN CARLOS R
IPC: A61P21/00
Filed: 2002-02-21
Abstract: In the present invention, there is disclosed the use of a carbamate compound of the general formula I or II, where X represents a phenyl group being substituted with one to five halogen atoms selected from fluorine, chlorine, bromine and iodine; and Ri1, Ri2, Ri3, Ri4, Ri5 and Ri6 each independently represents a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms, which can be optionally substituted with a phenyl group, whereas this phenyl group is optionally substituted with substituents independently selected from the group consisting of halogen, alkyl groups having 1 to 4 carbon atoms, alkoxy groups containing 1 to 4 carbon atoms, amino groups, nitro groups and cyano groups; in a therapeutically effective amount for the preparation of a medicament for prevention or treatment of neurodegenerative diseases.
Patent BR-PI0214137-B8 (BR)
Title: anticorpo monoclonal humano ou porção de ligação a antígeno do mesmo que se liga especificamente ao cd40 humano e o ativa, linhagem celular de hibridoma isolado, composição farmacêutica compreendendo os mesmos, uso dos mesmos na fabricação de um medicamento e método de fabricação dos referidos anticorpos ou porção de ligação a antígeno do mesmo
Inventor: JOSE CORVALAN
IPC: C12N5/09
Filed: 2002-11-08
Abstract: anticorpos para o cd40, composição farmacêutica compreendendo os mesmos, uso dos mesmos na fabricação de um medicamento, linhagem de célula isolada, molécula de ácido nucléico isolada, vetor compreendendo a mesma, célula hospedeira e método de fabricação dos referidos anticorpos. a presente invenção refere-se a anticorpos e porções de ligação a antígeno dos mesmos que se ligam especificamente ao cd40, de preferência cd40 humano e que funcionam como agonistas do cd40. a invenção também refere-se a anticorpos anti-cd40 humanos e porções de ligação a antígeno dos mesmos. a invenção também refere-se a anticorpos que são quiméricos, biespecíficos, derivatizados, anticorpos com cadeia simples ou porções de proteínas de fusão. a invenção também refere-se a imunoglobulinas de cadeia pesada e leve isoladas derivadas de anticorpos anti-cd40 humanos e moléculas de ácido nucléico que codificam tais imunoglobulinas. a presente invenção também refere-se a métodos de fabricação de anticorpos anti-cd40 humanos, composições compreendendo esses anticorpos e métodos de uso dos anticorpos e composições para diagnóstico e tratamento. a invenção também proporciona métodos de terapia genética usando moléculas de ácido nucléico que codificam as moléculas de imunoglobulina de cadeia pesada e/ou leve que compreendem os anticorpos anti-cd40 humanos. a invenção também refere-se a animais transgênicos compreendendo as moléculas de ácido nucléico da presente invenção.
Patent EP-1411956-B8 (EP)
Inventor: ZOPPETTI GIORGIO
IPC: A61P37/04
Filed: 2002-07-26
Granted: 2005-10-05
Abstract: The present invention relates to the use of N,O oversulfated K5 derivatives having a degree of sulfation higher than 3.2 or of their pharmaceutically acceptable salts for the preparation of pharmaceutical compositions for treating the infection and the consequent HIV/ADS disease.
Patent EP-1440120-B8 (EP)
Inventor: EICHENAUER HERBERT
IPC: C08L77/00
Filed: 2002-09-04
Granted: 2009-06-17
Abstract: A thermoplastic molding composition having an improved profile of properties is disclosed. The composition contains A) a graft rubber that is a product of free-radical emulsion polymerization of vinyl monomers in the presence of rubber a) that is present in latex form and having a glass transition temperature below 0° C., using at least one peroxydisulfate compound as an initiator, and B) a graft rubber that is a product of free-radical emulsion polymerization of vinyl monomers in the presence of at least one rubber b) that is present in latex form and having a glass transition temperature below 0° C., using at least one redox system as an initiator, and C) at least one graft polymer, that is a product of solution, bulk or suspension polymerization of a grafted phase that contains a member selected from the group consisting of styrene and acrylonitrile in a weight ratio of 90:10 to 50:50 therebetween, in the presence of a rubber, and wherein the weight ratio of introduced graft monomers to introduced rubber is 50:50 to 97:3.