baber/WOPTO huggingface dataset:
Patent NZ-560962-A (NZ)
Title: Methods of making pharmacokinetically improved compounds using sarcosine functional residues or groups and pharmaceutical compositions comprising said compounds
Inventor: CAMPBELL STEWART
IPC: A61K31/53
Filed: 2006-02-21
Abstract: A method for modulating the pharmacokinetic properties of a compound, in particular Vardenafil. The method comprises attaching a functional group, which is a sarcosine residue or sarcosine derivative, to the active compound by (a) replacing a nonessential residue or (b) substituting a nonessential residue of the compound with the functional group. The pharmacokinetic property can be increased solubility, lower IC50 or reduced non-specific protein binding.
Patent NZ-564803-A (NZ)
Title: Fabricating a metal beam
Inventor: WINDOW JOHN
IPC: E04C3/40
Filed: 2006-06-05
Abstract: A method of fabricating a metal beam for use as a structural building member in building construction, the metal beam comprising two face plates of sheet metal held mutually spaced apart by a reinforcing web 6 extending perpendicularly to each of the face plates and secured thereto by welding or by brazing, characterised in that, each face plate is formed with a row of slots 5 which together follow a line of engagement between the face plate and the supporting web 6, the reinforcing web 6 is formed along each longitudinal edge with an array of edge projections 8 sized and spaced apart to engage with the rows of slots 5 to locate the reinforcing web 6 along the line of engagement with each face plate as defined by the rows of slots 5, at least some of the edge projections 8 are sized to pass completely through the slots 5 with which they engage, to emerge on the opposite side of the respective face plates where they are bent so as temporarily to retain the supporting web 6 located along the line of engagement defined by the rows of slots 5, while thus temporarily retained, each face plate is welded or brazed to the supporting web 6 along the line of engagement there between, and on completion of the welding or brazing, all edge projections 8 of the supporting web 6 which pass completely through the face plates to stand proud on the other side are removed by grinding, to finish flush with the outer faces of the respective face plates.
Patent NZ-565960-A (NZ)
Title: Controlled release pharmaceutical compositions for acid labile drugs
Inventor: SHLIEOUT GEORGE
IPC: A61K38/46
Filed: 2006-08-15
Abstract: Disclosed is an enteric coating comprising a) at least one film-forming agent selected from the group consisting of cellulose acetate phthalate, hydroxypropyl methylcellulose acetate succinate, hydroxypropyl methylcellulose phthalate, methacrylic acid-ethyl methacrylate-copolymer, and mixtures of said film-forming agents; b) a plasticizer which is a mixture of cetyl alcohol and triethyl citrate; which are collectively present in an amount of greater than 3 percent by weight relative to the film forming agent and wherein the weight to weight ratio of cetyl alcohol to triethyl citrate is from 0.05: 1 to 1.1; and c) dimethicone as an anti-sticking agent in an amount of 1.5 to 3 percent by weight relative.
Patent NZ-569112-A (NZ)
Title: Supply chain management software for tracking carbon credits and emissions
Inventor: MACKINNON MARK DANIEL
IPC: G06Q10/00
Filed: 2008-06-13
Abstract: The system for producing carbon neutral wool products includes input means for accessing input data; and processing means for processing the input data to generate output data. The input data includes: (i) wool specification data representing specifications of wool lots produced by a plurality of farms; (ii) product specification data representing specifications of a wool product to be produced from the wool lots; (iii) greenhouse gas store data representing unallocated greenhouse gas storage of the farms; (iv) life cycle emissions data representing greenhouse gas emissions generated by a post-farm life cycle of the product; and (v) farm emissions data representing greenhouse gas emissions generated by production of the wool lots by each of the farms. The output data includes farm product data represents amounts of the wool lots to be supplied by the farms to produce the product and one or more corresponding amounts of the unallocated greenhouse gas storage to be allocated such that the total amount of greenhouse emissions generated by a life cycle of the product does not exceed the total amount of greenhouse gas storage provided by allocating the corresponding amounts of the unallocated greenhouse gas storage, so that the wool product is carbon neutral.
Patent NZ-570228-A (NZ)
Title: Thermoplastic belt connector comprising two leafs, each leaf having a flat side and at least two knuckles
Inventor: DEGROOT MICHAEL
IPC: B65G15/32
Filed: 2007-01-31
Abstract: A toothed belt connector (10) for connecting two ends (14, 16) of a belt segment (12) is disclosed. The connector (10) has two leaves (20, 22) that are adapted to be connected to each other by knuckles (28, 30) along one or more teeth (39). Each knuckle (28, 30) has at least one hole (42) extending through tooth portions so that when the holes (42) are in registry, a pin (32) can be extended through the holes (42) to connect the leaves (20, 22) at the teeth (39). The leaves (20, 22) can be adjoined to the ends (14, 16) of a belt (12) to make the belt (12) endless. The tip end of each knuckle (28, 30) can be beveled or it can have a stepped finger that fits into a cut-out on the opposite leaf to keep the end of the knuckle (28, 30) from protruding as the belt (12) wraps around a sprocket.
Patent NZ-571174-A (NZ)
Title: Anti-TAT226 antibodies and immunoconjugates
Inventor: LIANG WEI-CHING
IPC: C12N15/13
Filed: 2007-03-16
Abstract: Disclosed is a monoclonal antibody that binds to Tumor-associated Antigenic Target no. 226 (TAT226), wherein the antibody comprises (I) an HVR-H1 comprising the amino acid sequence of SEQ ID NO:4; (2) an HVR-H2 comprising the amino acid sequence of SEQ ID NO:5; (3) an HVR-H3 comprising an amino acid sequence that conforms to the consensus sequence of SEQ ID NO: 12; (4) an HVR-L1 comprising the amino acid sequence of SEQ ID NO:12; (5) an HVR-L2 comprising the amino acid sequence of SEQ ID NO:13; and (6) an HVR-L3 comprising an amino acid sequence that conforms to the consensus sequence of SEQ ID NO:19. Further disclosed is a monoclonal antibody that binds to TAT226 , wherein the antibody comprises a heavy chain variable domain having at least 95% sequence identity to an amino acid sequence selected from SEQ ID NO:21-25 and a light chain variable domain having at least 95% sequence identity to an amino acid sequence selected from SEQ ID NO:26-31, and wherein said antibody that binds TAT226 has a dissociation constant (KD) of <10 nM.
Patent NZ-573015-A (NZ)
Title: Triazolopyrazine compounds useful for the treatment of degenerative & inflammatory diseases
Inventor: ANDREWS MARTIN JAMES INGLIS
IPC: A61K31/4985
Filed: 2007-05-30
Abstract: Disclosed is a triazolopyrazine derivative of formula (III), or a salt, solvate, prodrug, stereroisomer, isotopic variant or tautomer thereof, wherein the substituents are as defined in the specification. Also disclosed is the use of the above compound to treat a condition characterized by ECM degradation, diseases involving inflammation, or rheumatoid arthritis.
Patent NZ-573544-A (NZ)
Title: Pyrrolotriazine compounds as kinase inhibitors
Inventor: FINK BRIAN E
IPC: A61K31/53
Filed: 2004-12-23
Abstract: Disclosed is the use of one or more compounds of formula III wherein X is -NH-; n is 1 or 2 and wherein the rest of the substituents are disclosed within the specification, in the preparation of a medicament for treating a proliferative disease, a medicament for treating diseases associated with signal transduction pathways operating through growth factor receptors or a medicament for modulating receptor tyrosine kinase activity. (62) Divided Out of 548070
Patent NZ-580965-A (NZ)
Title: Liquid control valve with actuator, typically float arm that moves combined bleed and vent element to open valve, and with inlet pressure seating diaphragm to close valve
Inventor: CRICHTON DAVID GORDON ARTHUR
IPC: F16K7/12
Filed: 2009-11-05
Abstract: A pressurised liquid control valve device has a body assembly 1, 5 containing a flexible member 7 which divides an internal chamber 6 into a liquid flow section and a liquid bleed section. The area of the flexible member 7 presented to the bleed 5 section is substantially larger than that presented to the flow section. An inlet 2 and an outlet 3 both join with the flow section but are separated from one another therein by a port 4 closed and sealed by the flexible member 7. A bleed passage 11 joins the inlet 2 to the bleed section which is also vented, vent 11a. A combined bleed passage valve and vent valve element 15 is mounted in the bleed passage 11 and is connected to an actuation member 14 adapted to be operable by an outside influence to operate the valve device. In an opening mode the vent 11a is open and the bleed passage 11 closed enabling an opening spring 10 to displace the flexible member 7 away from the port 4. In a valve device closed mode the vent 11a is closed and the bleed passage 11 opened to introduce pressure at the inlet 2 to the bleed section and so cause the flexible member 7 to seal onto the port 4. A liquid flow restriction 18 is provided in the inlet 2 between the valve seat 4 and the inlet to the bleed passage 11.
Patent NZ-582417-A (NZ)
Title: Device for automatically dispensing a loop of a continuous web of material and withdrawing it after use.
Inventor: GORRES KATHLEEN
IPC: B65H20/00
Filed: 2008-05-16
Abstract: A device is disclosed for dispensing predetermined segment lengths of a continuous web of material. The device comprises a base member (12) adapted for mounting on a suitable surface and a front housing (16) adapted to be connected to the base member (12) to form an enclosure. The enclosure comprises a lower compartment to receive processed segment lengths of the web, an upper compartment extending forward of the lower compartment to receive a supply of the web (34) and an unobstructed opening (46) formed in the bottom of the front housing. A web material feeding means (26) is positioned in the upper compartment to feed the web of material from the supply (34) over the front edge causing the web of material to cascade down past the lower compartment and out through the opening to form depending loop (44) of unprocessed web material. A web material take-up means (28) is mounted in the lower compartment for retracting processed web material into the housing and can retract the depending loop (44) of web material completely inside the housing (16) and away from the open bottom of the housing (46). Separate individual feeding motor and take-up motor means are operatively connected to the feeding means (26) and the take-up means (28). A sensing means is provided for detecting a requirement for feeding of said web of material out and determining when to initiate a take-up operation for retracting the depending loop (44) and a control means is provided for operating the motors in response to output from the sensing means. In operation a segment of the continuous web material is dispensed from within the housing for use and is thereafter entirely withdrawn into the housing (16) through the opening (44).
Patent NZ-582874-A (NZ)
Title: Methods for treating anxiety
Inventor: DONELLO JOHN E
IPC: A61K31/40
Filed: 2008-07-08
Abstract: Disclosed is the use of a compound of formula (I) in the manufacture of a medicament for treating anxiety wherein X is CH2 or CH2-CH2, A is aryl or heteroaryl having 0, 1, 2, or 3 atoms selected from the group consisting of N, S, and O, wherein A has 0, 1, 2, or 3 substituents independently selected from the group consisting of 0 to 8 carbon atoms, from 0 to 3 oxygen atoms, from 0 to 3 halogen atoms, from 0 to 2 nitrogen atoms, from 0 to 2 sulfur sulphur atoms, and from 0 to 24 hydrogen atoms. Anxiety disorders include generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, a phobic disorder, acute stress disorder, post-traumatic stress disorder, or mixed anxiety-depression. A is preferably pyridinyl, thienyl, furyl, quinolinyl, methylphenyl, or biphenyl
Patent NZ-588003-A (NZ)
Title: Process for the preparation of synthesis gas, ii
Inventor: DOORN SIEBOLT
IPC: C10J3/00
Filed: 2009-03-10
Abstract: Disclosed is a process for the production of synthesis gas, which involves the steps of a) preparing a vapour phase mixture comprising steam and at least one hydrocarbon or oxygenated hydrocarbon by atomizing of the at least one hydrocarbon or oxygenated hydrocarbon through a nozzle such that the at least one hydrocarbon or oxygenated hydrocarbon is present as droplets with a droplet size of less than 500 pm and the time to complete evaporation does not exceed 0.5 seconds, said at least one hydrocarbon or oxygenated hydrocarbon having an atmospheric boiling point in the range of -50 to 370 degrees C, said vapour phase having a H2O/C molar ratio of at least 2, and b) catalytic conversion of the vapour phase mixture into synthesis gas in a reformer. Also disclosed is the syngas produced by the process. Synthesis gas, also known as syngas, is a mixture of hydrogen and carbon monoxide and very often carbon dioxide.
Patent NZ-591100-A (NZ)
Title: Soluble canola protein isolate production
Inventor: SCHWEIZER MARTIN
IPC: A23J1/14
Filed: 2009-07-10
Abstract: A method of producing a canola protein isolate that has a canola protein content of 90 wt% (N x 6.5) d.b. and contain both the albumin and globulin protein fractions. The canola protein isolates are soluble and transparent in an acidic aqueous environment. The canola protein isolate is soluble in a beverage having a pH of 2.5 to 5 in phytic acid and can be used for human consumption, pet foods and aquaculture.
Patent NZ-595479-A (NZ)
Title: Faecal markers
Inventor: LEE MICHAEL
IPC: A22B5/00
Filed: 2010-03-09
Abstract: IP No. 595479 The disclosure relates to methods for analyzing an animal carcass, meat obtained therefrom, or product produced by or obtained from an animal for the presence or absence of fecal matter. The methods comprise analyzing an animal carcass, meat obtained therefrom, or product produced by or obtained from the animal for the presence or absence of a detectable marker, the presence of the detectable marker being indicative of the presence of fecal matter and the absence of the detectable marker being indicative of the absence of fecal matter, wherein the animal carcass, meat obtained therefrom, or product produced by or obtained from the animal has been obtained from an animal fed a composition comprising a supplement of the detectable marker and/or a precursor thereof. Wherein the detectable marker comprises a porphyrin ring or salt thereof. Wherein detection of the marker is used to identify and remove any faecal matter. Also described are compositions for feeding to an animal and for use in the methods.
Patent NZ-596250-A (NZ)
Title: Shellfish farming systems and methods
Inventor: SEATON MARK HAMISH
IPC: A01K80/00
Filed: 2011-11-07
Abstract: A shellfish farming system comprising a plurality of anchor points fixed to the sea floor, wherein an anchor line is slideably movable through bell shaped mouths attached to the anchors. A growing line arrangement is attached at connection points along the anchor line, wherein the growing line arrangement is floated upwards by attached buoyancy means. A growing line arrangement comprises growing lines on which the shellfish are cultivated. The anchor lines are free to slide through the bell shaped mouths attached to the anchor points which allows a harvesting boat to pull sections of the growing line to the surface for harvesting. A method of harvesting shellfish from the shellfish farming system is also included.
Patent NZ-596306-A (NZ)
Title: Winding device
Inventor: REIJERSEN-VAN BUUREN WILLEM JACOBUS
IPC: A01F15/07
Filed: 2010-05-07
Abstract: 596306 Disclosed is a winding device (14) for enveloping or packaging agricultural harvest bales (15). The device comprises a winding base (10) for receiving and for rotating the pressed harvest bale (15) and a guiding frame (13) for at least one winding material carrier (11, 12) for wrapping the bale (15) located on the winding base (10) with a web-shaped winding material (22, 23). The height of the guiding frame (13) can be adjusted in order to set the center (20) of the winding material (22, 23) at the height of the center (16) of the harvest bale (15) to be wrapped. To adapt the winding devices (14) guiding frame (13) to bales (15) of different bale diameters, the guiding frame (13) can be pivoted about a horizontal axis (26) located in parallel to the rotational axis (16) of the harvest bale.
Patent NZ-600477-A (NZ)
Title: Insulin analogues with chlorinated amino acids
Inventor: WEISS MICHAEL
IPC: C12N15/17
Filed: 2010-12-13
Abstract: Disclosed is an insulin analogue comprising a B-chain polypeptide incorporating a chlorinated phenylalanine located at position B24 wherein the chlorinated phenylalanine is para-monochloro-phenylalanine. Also disclosed is the use of an insulin analogue or a physiologically acceptable salt thereof for the preparation of a pharmaceutical composition formulated for administration to a patient for lowering of the blood sugar level of the patient, wherein said composition contains a physiologically effective amount of said insulin analogue or a physiologically acceptable salt thereof, wherein the insulin analogue or a physiologically acceptable salt thereof contains a B-chain polypeptide incorporating a chlorinated phenylalanine at position B24 wherein the chlorinated phenylalanine is para-monochloro-phenylalanine.
Patent NZ-602163-A (NZ)
Title: Crystalline forms of a 2-thiazolyl- 4-quinolinyl-oxy derivative, a potent hepatitis c viral inhibitor
Inventor: BERKENBUSCH THILO
IPC: A61K31/4709
Filed: 2009-09-14
Abstract: Disclosed is a crystalline form of quinolone thiazole pyrrolidine carboxamide of formula (I). Also disclosed is the use of the crystalline form in the manufacture of a medicament for treating hepatitis C virus infection in a mammal. Further disclosed is X-ray powder diffraction pattern comprising peaks at 4.8, 6.8, 9.6, 13.6, 17.3, 19.8 and 24.5 degrees 20 (plus or minus 0.2 degrees 2 theta) when measured using CuK alpha radiation.
Patent NZ-602662-A (NZ)
Title: Water dispersion type sex pheromone sustained release preparation
Inventor: YAMASHITA MIYOSHI
IPC: A01P19/00
Filed: 2012-09-26
Abstract: ABSTRACT - 602662 Disclosed herein is a water dispersion type sex pheromone sustained release preparation suitable for aerial spray over large-area agricultural fields or vast forests, which comprises at least: (i) an insect sex pheromone substance which is enclosed in a ring of an inclusion cyclodextrin, the inclusion cyclodextrin which encloses the insect sex pheromone substance, (ii) a non-inclusion cyclodextrin which does not enclose the insect sex pheromone substance, (iii) a water-soluble polymer, and (iv) water, wherein said insect sex pheromone substance is at least one insect sex pheromone substance selected from the group consisting of acetates, esters, aldehydes, alcohols, ketones, epoxides and hydrocarbons, each having 4 to 23 carbon atoms in total inclusive of the carbon number of unctional groups, and said water-soluble polymer is selected from the group consisting of polyvinyl alcohols, polyethylene glycols, polyvinyl pyrrolidones, sodium polyacrylates, polyacrylamides, carboxyvinyl polymers, polysaccharide-based natural polymers, microorganism polysaccharide-based natural polymers, animal-based proteins, a cellulose derivative and a starch derivative, and wherein said inclusion cyclodextrin and said non-inclusion cyclodextrin may be of the same or different types and are selected from the group consisting of α-cyclodextrin, β-cyclodextrin and (-cyclodextrin.
Patent NZ-610091-A (NZ)
Title: Antibodies
Inventor: TERRETT JONATHAN ALEXANDER
IPC: G01N33/574
Filed: 2011-10-19
Abstract: Disclosed is an isolated antibody that binds Cadherin-17 (CDH 17), comprising: (a) a heavy chain comprising an amino acid sequence with at least 85% sequence identity to SEQ ID NO: 27; and (b) a light chain comprising an amino acid sequence with at least 85% sequence identity to SEQ ID NO: 31; wherein the sequences are as defined in the specification. Also disclosed is the use of the antibody for treating cancer.
Patent NZ-613381-A (NZ)
Title: Back support
Inventor: GILBERT CHRISTOPHER EDWARD
IPC: A47C16/00
Filed: 2012-02-05
Abstract: A portable back support for a user which supports the back while seated and in particular, a combined lumbar and thoracic back support. The support has a generally convex lumbar support region (1) comprising a lateral support wing (3) positioned on either side of the lumbar support region (1) to provide lateral centralising support to each side and provide integral strength to the lumbar support so as to maintain equal shape in the lumbar support region (1). The lumbar support region (1) merges at right angles to a generally convex thoracic support region (2). A replaceable thoracic insert (8) is inserted in a support slot in the thoracic support region (2), and a replaceable lumbar insert (6) is inserted in a support slot in the lumbar support region (1). Each insert (6, 8) is independently deformable to provide a plurality of incremental adjustments to provide a range of support required by a user.
Patent NZ-619657-A (NZ)
Title: Creping methods using ph-modified creping adhesive compositions
Inventor: SULLIVAN PATRICK
IPC: D21H23/60
Filed: 2012-07-26
Abstract: Disclosed herein is a method for manufacturing a creped fiber web comprising providing a rotating cylindrical dryer surface, providing a creping adhesive composition or coating package having a pH boosted at least 0.5 pH units relative to its original base formulation pH in the range of from about 4.5 to about 9 by the addition of a pH modifier such as sodium hydroxide in order to chemically set a crosslinkable polymer component at least in part before applying the creping adhesive composition to the rotating cylindrical dryer surface to provide an adhesive dryer surface on which a fiber web can be transferred, dried, and creped.
Patent NZ-627936-A (NZ)
Title: Plant growth assembly
Inventor: JOHN KENDALL
IPC: A01G9/00
Filed: 2014-07-28
Abstract: Disclosed is a plant growth assembly and method to allow intensive growth of plants or vegetative organisms in earth or soil from seeds, stems, roots or plants. The assembly comprises a container portion, a dispersion portion and a support portion. The container or pot to grow the plants in comprises a top section that contains earth and the plants, and a bottom section for water or liquid fertilizer storage. The top section is above the bottom section and are joined together or separate items. The container portion joins with the dispersion portion that waters or irrigates plants using spray nozzles growing within a plant growth ring within the top section, the dispersion portion comprising an irrigation portion and/or a base portion, the dispersion portion at the centre of the support portion, the support portion encompassing the dispersion portion to support plants. The radially spaced plants around the periphery of the top section grow at an angle rather than vertically while being supported by the stakes or frame.
Patent NZ-628527-A (NZ)
Title: 2-substituted cephem compounds
Inventor: LIAO XIANGMIN
IPC: C07D505/24
Filed: 2013-10-29
Abstract: Disclosed are 2-substituted cephem compounds of formula (I), wherein the substituents are as defined in the specification. The compounds have a wide antimicrobial spectrum, in particular exhibit potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. An example of a compound of formula (I) is: (4S, 6R, 7R)-7- ((Z)-2- (2-aminothiazol-4-yl )-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-3-((4-((6,7-dihydroxy-4-oxo-1,4-dihydroquinoline-3-carboxamido)methyl)-1-azabicyclo[2.2.1]heptan-1-ium-1-yl)methyl)-4-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate