Patent SG-11201811323X-A (SG)
Title: Fluidic devices and methods of manufacturing the same
Inventor: EARNEY JOHN
IPC: G01N15/14
Filed: 2017-12-12
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111111111111111111111111111111111111111111111111111111111111111# Organization (10) International Publication Number International Bureau (43) International Publication Date ......0\" WO 2018/144138 Al 09 August 2018 (09.08.2018) WIP0 I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every BOIL 3/00 (2006.01) GO1N 15/14 (2006.01) kind of national protection available): AE, AG, AL, AM, (21) International Application Number: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, PCT/US2017/065855 CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (22) International Filing Date: HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, 12 December 2017 (12.12.2017) KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language: English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (30) Priority Data: TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. 62/452,923 31 January 2017 (31.01.2017) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant: ILLUMINA, INC. [US/US]; 5200 Illumina GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, Way, San Diego, CA 92122 (US). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: EARNEY, John, Gerhardt; 5200 Illumina TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Way, San Diego, CA 92122 (US). FULLERTON, Justin; EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 5200 Illumina Way, San Diego, CA 92122 (US). SMITH, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Kaleb; 5200 Illumina Way, San Diego, CA 92122 (US). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, _ VENKATESAN, Bala, Murali, K.; 499 Illinois Street, KM, ML, MR, NE, SN, TD, TG). Suite 210, San Francisco, CA 94158 (US). = Declarations under Rule 4.17: (74) Agent: DIERKER, Julia, Church et al.; Dierker & Ka- — as to the identity of the inventor (Rule 4.17(i)) = vanaugh, P.C., 3331 W. Big Beaver Road, Suite 109, Troy, _ as to applicant's entitlement to apply for and be granted a MI 48084 (US). patent (Rule 4.1700) = = (54) Title: FLUIDIC DEVICES AND METHODS OF MANUFACTURING THE SAME (57) : An example method includes providing a working stack having a = first substrate layer, a second substrate layer, and a radiation-absorbing material = disposed between the first and second substrate layers. The working stack includes = 104 c--100 a cavity therein having a designated liquid. A bonding interface is defined between = = = the radiation-absorbing material and at least one of the first substrate layer or the second substrate layer. The bonding interface has a film of the designated liquid. The method also includes directing radiation onto the bonding interface to form a seal. The seal separates the cavity from an outer area of the perimeter perimeter 112 0 bonding interface. The method also includes directing the radiation the outer onto = = = area of the bonding interface to secure the first and second substrate layers together. The perimeter seal impedes an ingress of bubbles from the outer area into the cavity — = as the radiation is directed onto the outer area. _ = L Il GC M Il 7r 71' FIG. 1 1-1 --.... 00 1-1 0 ei C [Continued on next page] WO 2018/144138 Al MIDEDIMOMMIONEEMOMMMOIVOMMODEVOIMI Published: — with international search report (Art. 21(3))