baber/WOPTO huggingface dataset:
Patent EA-002383-B1 (EA)
Title: Fungicidal mixture
Inventor: SCHELBERGER KLAUS
IPC: A01N43/40
Filed: 1998-05-20
Abstract: 1. A compound of formula (I):   wherein R31 and R32 can individually be OCH3; OC2H5; SCH3; SC2H5; R31 and R32 can be also connected to form OCH2CH2O; O(CH2)3O; S(CH2)2S; S(O)(CH2)2S; S(O)(CH2)2S(O); S(O)2(CH2)2S(O); S(O)2(CH2)2S(O)2; S(CH2)2O; S(O)(CH2)2O; S(O)2(CH2)2O; O(CH2)[CH(CH2OH)]O; O(CH2)[C(CH2OH)(CH2OH)]O; OCH(COOCH3)CH(COOCH3)O; OCH(COOC2H5)CH(COOC2H5)O; OCH2C(COOCH3)(COOCH3)CH2O; OCH2C(COOC2H5)(COOC2H5)CH2O; OCH2CH(CH3)O; SCH2CH2NH; OCH2CH(CH2CH2OH)O or OCH2C(CH2OH)2CH2O; O(CH2)CH(CH2SCH3)O; O(CH2)CH(CH2SOCH3)O; R4 is S(O)nR26; R26 is CH3 or CH2CH3; Z is C-R16; R13 and R15 are H; R12 is halogen; R16 is H or halogen; R14 is CF3, OCF3; SF5; and R33 is CH3; R5 is NH2, alkylamino , wherein alkyl can be substituted with NO2, halogen, CN, alkoxycarbonyl, OH, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl or carbamoyl, or R5 is a radical, having the formula   wherein R4, R12, R13, R14, R15, Z and R33 are identical, correspondingly, R4, R12, R13, R14, R15, Z and R33 in the formula (I) above; or insecticide active salt thereof. 2. The compound of Claim 1, wherein R14 is SF5 or OCF3. 3. The insecticide composition, comprising the compound of formula (I) or insecticide acceptable salt thereof according to Claim 1, and insecticide acceptable carrier. 4. The insecticide composition according to Claim 3, comprising 0,05 to 95% by weight of a compound of formula (I). 5. A method of controlling pests at a locus which comprises applying to the locus a compound of formula (I) or a pesticidally acceptable salt thereof as defined in Claim 1, or a composition as defined in Claim 3. 6. A process for the preparation of a compound as claimed in Claim 1, said process comprising reacting a compound having the formula   wherein R4, R5, R12, R13, R14, R15, Z and R33, are as defined in Claim 1 and R34 is oxygen or sulfur, with a compound of formula (III), selected from the group: HOCH3; HOC2H5; HSCH3; HSC2H5; HOCH2CH2OH; HO(CH2)3OH; HS(CH2)2SH; HS(CH2)2OH; HO(CH2)[CH(CH2OH)]OH; HO(CH2)[C(CH2OH)(CH2OH)]OH; HOCH(COOCH3)CH(COOCH3)OH; HOCH(COOC2H5)CH(COOC2H5)OH; HOCH2C(COOCH3)(COOCH3)CH2OH; HOCH2C(COOC2H5)(COOC2H5)CH2OH; HOCH2CH(CH3)OH; HSCH2CH2NH2; HOCH2CH(CH2CH2OH)OH; HOCH2C(CH2OH)2CH2OH; HO(CH2)CH(CH2SCH3)OH or HO(CH2)CH(CH2SOCH3)OH.
Patent EA-005116-B1 (EA)
Title: A NOVEL CRYSTALLINE FORM OF 6-HUDROXY-3-(4-[2-PIPERIDIN-1-YL)ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE HYDROCHLORIDE
Inventor: LUKE WAYNE DOUGLAS
IPC: C07D333/64
Filed: 2001-10-18
Abstract: 1. A non-solvated, anhydrous crystal form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]-phenoxy)-2-(4methoxyphenyl)benzo[b]thiophene hydrochloride having an X-ray diffraction pattern which comprises at least one of the following peaks: 7.3+-0.2, 15.5+-0.2, 15.9+-0.2, and 17.6+-0.2 in 2theta when obtained from a copper radiation source (CuKalpha; λ(1.54056A). 2. The crystalline compound according to Claim 1 wherein said X-ray diffraction pattern further comprises at least one of the following peaks: 17.9+-0.2, 18.2+-0.2, 18.9+-0.2, and 21.5+-0.2 in 2theta. 3. A pharmaceutical formulation comprising the crystalline compound of Claim 1 and one or more pharmaceutical carriers, diluents, or excipients. 4. A process for preparing a compound of Claim 1 which comprises crystallizing 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride from a crystallization solvent selected from the group consisting of: methanol or aqueous methanol, ethanol or isopropanol; and subsequently drying the resulting solid to a constant weight. 5. The process according to Claim 4 wherein the ratio of water to methanol (v:v) is between 20% and 5%. 6. The process according to Claim 5 where the ratio is 15%. 7. The compound of Claim 1 for inhibiting osteoporosis. 8. The use of a compound of Claim 1 for the manufacture of a medicament for inhibiting osteoporosis.
Patent EA-006451-B1 (EA)
Title: Method for preparing fibres contained in a pulp suspension
Inventor: DOELLE KLAUS
IPC: D21H19/38
Filed: 2003-02-03
Abstract: The invention relates to a method for preparing fibres contained in a pulp suspension, comprising the following steps: provision of the fibres in the form of a suspension with a predeterminable solid concentration; loading of the fibres with a precipitation product; grinding of the fibres loaded with the precipitation product to produce precipitation product particles with maximum dimensions ranging between approximately 0.05 and 5 mkm. The invention is characterised in that crystalline precipitation product particles are produced and said production of the latter takes place in an online process directly in the stock preparation line.
Patent EA-007217-B1 (EA)
Title: Casein derived peptides and uses thereof in therapy
Inventor: SIDELMAN ZVI
IPC: A61K38/08
Filed: 2001-03-01
Abstract: The present invention relates to use peptide preparation caseincydine derived from native casein for manufacturing a pharmaceutical composition for inducing hematopoiesis, capable of stimulating autologous bone marrow or peripheral blood stem cell transplantation (ASCT) or allogeneic bone marrow transplantation (BMT) in a myeloablated recipient and for preventing or treating disorders of lipidic metabolism, diabetes and viral-related infection.
Patent EA-009902-B1 (EA)
Title: Androgen receptor modulators
Inventor: HU LAIN-YEN
IPC: A61P5/28
Filed: 2005-01-31
Abstract: The present invention is directed to a new class of 4-oxo-benzonitriles, their use as androgen modulators, and to their use in the treatment of alopecia.
Patent EA-011951-B1 (EA)
Title: Anti-epcam immunoglobulins
Inventor: PETERS MALTE
IPC: A61K39/395
Filed: 2005-02-09
Abstract: The invention relates inter alia to a method of treating tumorous disease in a human patient by administering to the patient a human immunoglobulin specifically binding to the human EpCAM antigen, the immunoglobulin exhibiting a serum half-life of at least 15 days, the method comprising the step of administering the immunoglobulin no more frequently than once every week, preferably no more frequently than once every two weeks.
Patent EA-016625-B1 (EA)
Title: Management of breakthrough bleeding in extended hormonal contraceptive regimens
Inventor: SACHSE ANDREAS
IPC: A61K31/567
Filed: 2005-04-29
Abstract: The present invention relates to a method for female hormonal contraception which comprises the monophasic continuous administration of a hormonal contraceptive useful to manage bleeding problems. Wherein a oral contraceptive comprises 20 mg of ethinyl estradiol and 3 mg of drospirenone administered daily for a first period which is 24 days and then said oral contraceptive is administered daily for a second period which is maximum 96 days during which (a) the female initiates a break in said administration of 3 to 6 days or (b) if said break is not initiated during said maximum 96 days, the female initiated a break which is 3-6 days at the end of the period which is 96 days (1). After said break administration of said oral contraceptive is continued with the administration/break in accordance with the above-described procedure.
Patent EA-013518-B1 (EA)
Title: Crystalline polymorphic forms of monosodium n-[8-(2-hydroxybenzoyl)amino]caprylate
Inventor: LEVCHIK HALINA
IPC: C07C235/60
Filed: 2005-05-06
Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate ("SNAC"), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
Patent EA-011555-B1 (EA)
Title: A process for the preparation of [1,4,5]-oxadiazepine derivatives
Inventor: FABER DOMINIQUE
IPC: C07D273/06
Filed: 2005-10-25
Abstract: A process for the preparation of [1,4,5]-oxidiazepine derivatives by reaction of 4,5-diacyl-[1,4,5]-oxidiazepines with a base.
Patent EA-017989-B1 (EA)
Title: Vehicle and method for improving its performance
Inventor: MISHUTA DMITRIJ VIKTOROVICH
IPC: B60K6/10
Filed: 2009-11-30
Abstract: The invention relates to transport engineering. Object of the invention is to provide a high performance vehicle. Vehicle (1) includes (Fig. 1) the motor (2) connected to the chassis (3) of the vehicle (1) through the transfer devices (4-7). The system (4) of engagement of the flywheel masses includes sealed enclosure filled with fluid - magnetic fluid. The flywheel is inside a sealed enclosure. Engine driven member (2) is equipped with a sensor (22) electrically connected to the system (24-25) applying an electric signal, which is connected with the fluid through the sealed enclosure and driven member (14) of the motor. Method of improving the performance in such vehicle is to use the power of the flywheel masses during the start and braking of the vehicle (1) through the system (4) of engagement of the flywheel masses, and the energy of the flywheel masses is also used in the intervals between the start and braking of the vehicle. Such reduction efforts due to the increase of the torque of the motor (2) determined by the continuously variable speed of its output member (14) during the start, running and stoppage increases the efficiency, reliability and stability of the crank mechanism (11-14) of the motor (2), as well as transmission elements (5-7) of the transmission of the transport means (1). This ensures longer service life of the vehicle, reducing fuel consumption and improvement of its ecological characteristics.
Patent EA-019600-B1 (EA)
Title: Control valve assembly of an compressed-air brake for a rail vehicle
Inventor: CZYPIONKA SIMON
IPC: B60T15/18
Filed: 2010-09-20
Abstract: The invention relates to a control valve assembly for operating at least one associated brake cylinder (17) of a pneumatic brake of a rail vehicle, comprising a valve support (1) which is fixed on a vehicle frame in proximity to the brake cylinder (17) such that it is accessible from the outside and comprises several pipe connections (11a, 11b, 11c) for distributing the compressed air. According to the invention, at least one pipe part and a main part are detachably fixed to said valve support via flange surfaces (6a, 6b) associated to each part, both flange surfaces (6a, 6b) of the valve support (1) being disposed adjacent and at an angle to one another.
Patent EA-017386-B1 (EA)
Title: Tetrasubstituted pyridazine hedgehog pathway antagonists
Inventor: BASTIAN JOLIE ANNE
IPC: A61K31/501
Filed: 2009-11-05
Abstract: The present invention provides novel tetrasubstituted pyridine hedgehog pathway antagonists useful in the treatment of cancer.
Patent EA-023920-B1 (EA)
Title: Powder inhaler
Inventor: KAEMPER MARKUS
IPC: A61M15/00
Filed: 2010-09-30
Abstract: The invention relates to an inhaler for inhaling powdery pharmaceuticals from capsules, comprising a bottom part (6), a plate (3) received in the bottom part (6), a mounting (18) introduced in the bottom part (6), a mouthpiece (2) that can be latched to the bottom part (6) on the plate (3), a cover (1) that covers the mouthpiece (2) in a closed position, and an actuating member (7, 10), which can be set in motion from a position of rest and in the process cooperates with at least one needle (8, 11) that can pierce the mounting (18), said needle being located in a needle holder of the inner actuating member (10). To improve the operability of the inhaler according to the invention an exchange tube (22) can be inserted in the mounting (18) through the mouthpiece (2), the tube forming a discharge channel and comprising a capsule chamber (21) with the capsule contained therein and being releasably secured in its position of use in the inhaler and extending through the mouthpiece (2).
Patent EA-019418-B1 (EA)
Title: Heating device for a device for transporting a fluid containing a hydrocarbon
Inventor: BIGEX THIBAUD
IPC: F16L53/38
Filed: 2011-03-22
Abstract: The invention relates to a heating device (20) for a device (10) for transporting a fluid containing a hydrocarbon, said heating device comprising a rigid structure (22) extending between two lateral walls (22a, 22b), forming a space (23) between the lateral walls (22a, 22b), a flexible membrane (21) comprising heating means and extending into the space (23) in order to define, in said space (23), an inner cavity (23a) and an outer cavity (23b) at least partially surrounding the transport device (10), and pumping means (24) designed to supply a fluid to the inner cavity (23a), remove said fluid therefrom, or keep said fluid therein, in order to bring the membrane (21) into contact with the transport device (10) so as to heat same.
Patent EA-022191-B1 (EA)
Title: Method for producing gas-filled triple glazing
Inventor: RIPOCHE XAVIER
IPC: E06B3/677
Filed: 2011-01-31
Abstract: The invention relates to a method for producing gas-filled triple glazing, said method comprising a pre-assembly step during which three glass sheets (1, 2, 3) are positioned next to each other, at least one of said glass sheets (1, 2, 3) being provided with a spacer (4, 5, 4') and each glass sheet (1, 2, 3) being inclined at an angle (α, β) of between 0 and 10° in relation to the adjacent glass sheet in such a way as to form two cavities (8, 9), each cavity (8, 9) being between two adjacent glass sheets; a step of filling the two cavities by injecting gas into said two cavities (8, 9) at the same time, by means of nozzles; and a step of pressing glass sheets (1, 2, 3) against each other in order to seal the triple glazing. The invention enables triple glazing to be produced rapidly.
Patent EA-025227-B1 (EA)
Title: Pane and method for production thereof
Inventor: REUL BERNHARD
IPC: H05B3/84
Filed: 2011-02-15
Abstract: The present invention relates to a pane with an electrical connection element, comprising a substrate made of glass (1) with a first coefficient of thermal expansion, an electrically conductive structure (2) with a layer thickness of from 5 to 40 μm on a region of the substrate (1), a connection element (3) with a second coefficient of thermal expansion, wherein the difference between the first and second coefficients of thermal expansion is ≥5×10/°C, a layer of soldering compound (4), which electrically connects the connection element (3) to subregions of the electrically conductive structure (2), wherein the soldering compound (4), which exceeds a layer thickness t of 50 μm, emerges from the interspace between the connection element (3) and the electrically conductive structure (2) with an exit width b<1 mm, in relation to the contact face of the connection element (3).
Patent EA-026198-B1 (EA)
Title: Multipurpose gel for vaginal dryness with direct and delayed effect
Inventor: BARTORELLI ALBERTO
IPC: A61P15/02
Filed: 2011-12-02
Abstract: The present invention relates to topical vaginal compositions in gel form containing immune mediators, growth factors, chemotactic factors and antibacterial/antiviral factors extracted from bovine colostrum, and optionally other ingredients with complementary activity.
Patent EA-025256-B1 (EA)
Title: Composition useful for the treatment of lipid metabolism disorders
Inventor: KOVERECH ALEARDO
IPC: A23L33/15
Filed: 2012-04-24
Abstract: The present invention relates to a composition useful for the treatment of lipid metabolism disorders, comprising one or more of the following active ingredients: (a) extract of rice fermented with Monascus purpureus, (b) at least one omega-3 fatty acid, (c) L-carnitine or a salt thereof; and one or more of the following active ingredients: (d) at least one policosanol or a natural extract containing policosanols; (e) resveratrol or a natural extract containing resveratrol; (f) Coenzyme Q10; and (g) at least one vitamin.
Patent EA-031332-B1 (EA)
Title: Композиция для лечения свища
Filed: 2012-10-03
Abstract: Изобретение относится к способу лечению свища, включающему стадию ректального введения субъекту, нуждающемуся в этом, фармацевтически эффективного количества дозы сухих частиц, состоящих из активированного угля, где указанные частицы доставляют в прямую кишку субъекта с использованием движущей текучей среды.
Patent EA-028051-B1 (EA)
Title: Sealing device, in particular for a shaft inserted transversely in a vessel of fluids under pressure or granular material in movement
Inventor: DELLA NEGRA ANGELICO
IPC: F16J15/18
Filed: 2013-07-19
Abstract: A sealing device for a vessel (12) to achieve a fluid-tight seal in an aperture (14) made in the lateral wall (18) of said vessel (12), into which aperture (14) a shaft (11) is inserted. The sealing device comprises first sealing means (24) disposed in contact with the shaft (11) in the zone of said aperture (14), and second sealing means, comprising a containing body (22) and a flexible connection element (43). The first sealing means (24) comprise a plurality of sealing rings (25), disposed coaxial to the shaft (11) and in contact with the latter, and a containing tube (32) to contain the sealing rings (25). The lateral wall (18) of the vessel (12) comprises an interface flange (17). A closing flange (37) is connected to the interface flange (17) and to a flanged end (23) of the containing body (22) by means of attachment means (47, 48) and is positioned in contact with the containing tube (32) and with the flexible connection element (43) to keep the first sealing means (24) in a determinate axial position with respect to the shaft (11).
Patent EA-032621-B1 (EA)
Title: Indazolecarboxamides, processes for their preparation, pharmaceutical preparations comprising them and their use for producing medicaments
Inventor: BOTHE ULRICH
IPC: A61K31/4439
Filed: 2014-12-16
Abstract: The present invention relates to novel 6-substituted indazoles of formula (I) having a carboxamide side chain, to processes for their preparation, to their use for the treatment and/or prophylaxis of IRAK4-mediated diseases, in particular for the treatment and/or prophylaxis of tumor disorders, dermatological disorders, gynaecological disorders, cardiovascular disorders, pulmonary disorders, ophthalmological disorders, neurological disorders, metabolic disorders, inflammatory disorders, autoimmune disorders and pain.
Patent EA-031083-B1 (EA)
Title: Plant growth regulating compounds
Inventor: LACHIA MATHILDE DENISE
IPC: C07D409/14
Filed: 2015-02-24
Abstract: The present invention relates to novel heterocyclic derivatives of Formula (I)wherein the radicals W, W, R, R, X, X, Y, Y, Xand Xare defined in the claims, to processes for preparing them, to plant growth regulator and seed germination promoting compositions comprising them and to methods of using them for controlling the growth of plants and/or promoting the germination of seeds.
Patent EA-037387-B1 (EA)
Title: Laminate for application on a support plate and method for producing same
Inventor: SCHIEGL WALTER
IPC: B32B29/06
Filed: 2015-03-25
Abstract: Provided is a laminate for application on a support plate, the laminate comprising a resin-impregnated decorative layer and at least one resin-impregnated core layer, wherein the decorative layer and the at least one core layer are pressed together under high pressure and heat by a press; a thickness of a stack of the decorative layer and the at least one core layer after pressing is less than 2 mm; the decorative layer and the at least one core layer has a width of more than 1,800 mm; a surface of a layer arranged opposite to the decorative layer is provided with an embossed structure; the embossed structure corresponds in regard to depth and geometry to a structure produced by grinding; the geometry of the embossed structure corresponds to a grinding groove structure; the depth of the embossed structure has a mean roughness of less than 20 m, in particular less than 10 m.
Patent EA-034344-B1 (EA)
Title: Segmented molding core system of an injection mold, and method of injection molding hollow articles formed thereby
Inventor: HAIMOFF EFRAIM
IPC: B29C45/26
Filed: 2015-08-27
Abstract: The molding core system (260) is provided to manufacture molded hollow articles (100) with bulges containing multiple components configured with the ability of manipulation between its first molding position in which the said system is fully deployed and the second position in which the said system is made with ability of radial contraction and axial retraction into the second extracting position. The said system comprises an axially displaceable core feeding pin (280) and at least one of the radially displaceable core segments (270) extending around the core feeding pin (280). The outer surface of the core segments (270) in deployed configuration of the specified system essentially corresponds to the inner surface (S) of a molded hollow article (100). Core segments (270) contain the first group of dynamic segment elements (270A, 270B, 270C and 270D) and the second group of dynamic segment elements (270A', 270B', 270C' and 270D'), which all essentially protrude around the core feeding pin (280). The specified first group of elements of dynamic segments is made capable of radial movement towards the central axis X of the specified system, and the specified second group of elements of dynamic segments is made capable of radial movement towards the central axis X of the specified system, and additional axial movement in the direction opposite to that of retraction of the core feeding pin (280). A mold and a method of injection molding of substantially hollow articles having at least one opening that is substantially narrower than the widest part of article are also provided. The method is realized using the proposed molding core system.
Patent EA-032654-B1 (EA)
Title: [1,2,4]TRIAZOLO[4,3-b]PYRIDAZINES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES
Inventor: BRADBURY ROBERT HUGH
IPC: A61P35/00
Filed: 2015-07-24
Abstract: The present invention relates to compounds of Formula (I)or pharmaceutically-acceptable salts thereof, wherein R, Rand n have any of the meanings defined herein before in the description; processes for their preparation, pharmaceutical compositions containing them and their use as anti-proliferative and/or cell-killing agents.
Patent EA-034758-B1 (EA)
Title: New crosslinked polymer composition, structured layer and cable
Inventor: SMEDBERG ANNIKA
IPC: C08F210/18
Filed: 2015-08-19
Abstract: The present invention relates to a crosslinked polymer composition comprising a crosslinked polyolefin and decomposition product(s) of peroxides, wherein the polymer composition comprises, prior to crosslinking, a polyolefin and peroxide which is in an amount of less than 35 mmol -O-O-/kg polymer composition, characterized in that a non-degassed and 1 mm thick plaque sample of the crosslinked polymer composition that has been in a direct contact with a semiconductive composition comprising polymer and carbon black for 24 h at 70°C, after separation from the semiconductive composition, has an electrical DC-conductivity of 150 fS/m or less, at 70°C and 30 kV/mm mean electric field, wherein the electrical DC-conductivity is measured in accordance with "DC conductivity method", as described under "Determination methods", and said polymer composition comprises 2,4-diphenyl-4-methyl-1-pentene in an amount of less than 0.05 wt.% or comprises no 2,4-diphenyl-4-methyl-1-pentene. The invention also relates to a layered structure, cable, e.g. a power cable, and a process for producing a cable.