baber/WOPTO huggingface dataset:
Patent WO-2020086871-A1 (WO)
Title: Functionalized nanoparticle formulations for oral drug delivery
Inventor: ANCHORDOQUY THOMAS
IPC: A61K9/51
Filed: 2019-10-24
Abstract: Drug delivery systems comprising binding partners conjugated to a nanoparticle encapsulating a therapeutic agent formulated for oral administration, and methods of delivering therapeutic agents across the gastrointestinal epithelium.
Patent WO-2020092637-A1 (WO)
Inventor: OHLSSON HENRIK
IPC: G06F21/57
Filed: 2019-10-30
Abstract: Provided herein are methods and systems for determining a historical state of a dynamic network. The methods may comprise continuously obtaining data associated with a system from a plurality of different data sources; constructing a full history dynamic network (FHDN) of the system using the data; and providing a state of the system for a historical time instance in response to a query of the FHDN for the historical time instance.
Patent WO-2020102298-A1 (WO)
Title: Gas spring and damper assemblies as well as suspension systems including same
Inventor: VAN AARTSEN JAN
IPC: F16F9/084
Filed: 2019-11-13
Abstract: A gas spring and damper assembly (102; AS1) includes a damper assembly (DP1) and a gas spring assembly (GS1). The gas spring assembly (GS1) is axially coextensive with the damper assembly (DP1) and includes a flexible spring member (300), a first end member assembly (500) and a second end member assembly (400). The first end member assembly (500) includes a first wall portion (556) that extends about a longitudinal axis (AX) and defines an end member chamber (502). A second wall portion (596) projects outwardly beyond an outer peripheral surface portion (559) of the first wall portion (556). The second wall portion (596) at least partially defines an intermediate chamber (586) in fluid communication with the end member chamber (502) and is dimensioned to receive an associated control device (CD1). A third wall portion (572) at least partially defines an end member passage (600) through which the end member chamber (502) can be selectively placed in fluid communication with the spring chamber (302) by way of the intermediate chamber (586) and the associated control device (CD1).
Patent WO-2020112489-A1 (WO)
Title: Autonomous vehicle having independent steering
Inventor: NEWTON DEAN
IPC: B60W30/14
Filed: 2019-11-21
Abstract: A terminal tractor includes four independently steerable wheels, each with their own dedicated drive motor and each with their own dedicated steering device. The terminal tractor includes a controller operable to provide input commands to the drive motors and to the steering devices to operate the terminal tractor. The terminal tractor also includes a fifth wheel coupling which includes a lifting mechanism capable of raising and lowering the fifth wheel coupling in a single vertical direction.
Patent WO-2020231469-A1 (WO)
Inventor: TZENG YON-HUA
IPC: C30B25/18
Filed: 2019-12-06
Abstract: A method of diamond nucleation comprises the steps of providing a substrate and forming a metal layer on the substrate, wherein the metal layer comprises a catalyst and a transitional metal, the catalyst is copper, nickel or a combination thereof, and the transitional metal is tungsten, molybdenum or a combination thereof; providing a reaction chamber and disposing the substrate in the reaction chamber; providing a gas mixture in the reaction chamber, wherein the gas mixture includes a carbon-containing gas and hydrogen gas; causing the carbon-containing gas to react and form a graphene layer on the metal layer; and causing the graphene to react with the transitional metal and the carbon-containing gas to form diamond nuclei on the metal layer at a border between the graphene layer and the metal layer. The present invention also relates to a structure formed by the aforesaid method.
Patent WO-2020142197-A1 (WO)
Inventor: THOM STEFAN
IPC: G06F21/53
Filed: 2019-12-17
Abstract: Trusted execution of a workload payload is brokered among multiple trusted execution platforms. The workload payload is received from a source computing system and includes input data, trusted execution code, and one or more trusted execution policies. At least one of the multiple trusted execution platforms is selected based on the one or more trusted execution policies. A brokered payload is generated to include executable trusted execution code and the input data. The brokered payload is communicated to the selected at least one trusted execution platform. A brokered result generated from the brokered payload by the selected at least one trusted execution platform is received. A workload result based on the brokered result is returned to the source computing platform.
Patent WO-2020146309-A1 (WO)
Title: Machine électrique à aimants permanents intérieurs à structure de pont effilé
Inventor: LEE SEONG
IPC: H02K1/27
Filed: 2020-01-07
Abstract: L'invention concerne une machine électrique (20) comprenant un rotor (24) comportant des aimants permanents intérieurs (40, 42). Chaque pôle de rotor (32) comprend au moins une fente d'aimant central (36) dotée d'un aimant permanent (40) disposé en son sein et des première et seconde fentes d'aimant externe (38) comportant chacune un aimant permanent (42) disposé en leur sein. Les pôles de rotor définissent individuellement une ligne centrale radiale (34). Les première et seconde fentes d'aimant externe (38) sont positionnées sur des côtés circonférentiels opposés de la ligne centrale radiale et sont au moins partiellement positionnées à une plus grande distance radiale de l'axe central 28 que d'un bord radialement le plus à l'extérieur (44) de ladite fente d'aimant centrale (36). Les première et seconde fentes d'aimant externe (38) définissent individuellement un pont de matériau effilé (66) disposé entre la fente d'aimant externe (38) et un périmètre radialement externe (64) du noyau de rotor (30). Chacun des ponts de matériau effilé définit une épaisseur radiale variable (68) dont l'épaisseur radiale variable diminue à mesure qu'augmente la distance circonférentielle à partir de la ligne centrale radiale (34) du pôle.
Patent WO-2020146435-A1 (WO)
Title: Compositions and methods for detecting cardiotoxicity
Inventor: WEST MICHAEL
IPC: A61P35/00
Filed: 2020-01-07
Abstract: A method of screening a composition for cardiotoxicity comprising contacting the composition with cardiomyocytes that have increased fatty acid oxidation and/or diminished glucose oxidation. The cardiomyocytes are preferably prepared by overexpression of  COX7A1 . The cardiomyocytes are preferably provided in a micropattemed co-culture to provide a mature functional hPSC-CM cardiotoxicity model.
Patent WO-2020163325-A1 (WO)
Inventor: BAMDAD CYNTHIA
IPC: A01K67/027
Filed: 2020-02-04
Abstract: La présente invention concerne des anticorps anti-NME et leur utilisation dans le traitement ou la prévention de maladies. La présente invention concerne une méthode de traitement ou de prévention du cancer chez un sujet, qui consiste à administrer au sujet un anticorps dirigé contre un membre de la famille NME. Selon l'invention, la famille NME peut être la famille NME7.
Patent WO-2020163529-A1 (WO)
Title: Targeting cd24-siglec interactions for the treatment and prevention of nonalcoholic steatohepatitis
Inventor: LIU YANG
IPC: C07K19/00
Filed: 2020-02-05
Abstract: Provided herein are methods and compositions for the prevention and treatment of nonalcoholic steatohepatitis (NASH) by targeting the CD24-Siglec axis.
Patent WO-2020185564-A1 (WO)
Title: Systems and methods for hydro-based electric power generation
Inventor: BLODGETT LYNN
IPC: F03B7/00
Filed: 2020-03-06
Abstract: A hydrodynamic power generation assembly (10) and method of use therefor for generating electrical power from the combination of kinetic energy, hydrostatic energy, and turbulent energy of water. The power generation assembly (10) comprises a water accelerator assembly (40a, 40b) comprising a support structure (15) which is at least partially buoyant and a baffle panel member (or an array of baffle panel members) having an opening, inter-panel spacing, or flow passageway around the baffle panel(s). A hydropower converter (55) is supported from, by, or on the support structure (15) and is operatively coupled to a generator. The hydropower converter (55) is positioned behind baffle assembly (40a, 40b). Water flowing through or around the baffle assembly has an increased velocity relative the ambient current and therefore is capable of generating more power relative to the ambient water where power generation assembly is deployed. Particular types of hydropower converters suitable for use with the invention are turbines and water wheels.
Patent WO-2020185848-A1 (WO)
Title: Nozzle arrangement for applying fluids, and method for producing a main body of such a nozzle arrangement
Inventor: PAHL ANDREAS
IPC: B05C5/00
Filed: 2020-03-11
Abstract: The invention relates to a nozzle arrangement (1) for applying fluids, in particular thermoplastic adhesives, to a substrate, wherein the nozzle arrangement (1) has a main body (2) which is able to be connected, preferably exchangeably, to a mounting region of a distributor and which has an end-side side surface (3), wherein, in or on the end-side side surface (3) of the main body (2), there is provided at least one first outlet nozzle (4) for the fluid to be applied to the substrate, wherein, in the main body (2), there is formed a first fluid channel system (5), via which the at least one first outlet nozzle (4) is connected in terms of flow to a first fluid connector, which is provided in the main body (2) of the nozzle arrangement (1), wherein the nozzle arrangement (1) is a monolithic component produced by an additive production method.
Patent WO-2021080644-A1 (WO)
Inventor: ANDERSON MILTON
IPC: F04B27/18
Filed: 2020-04-22
Abstract: A variable stroke high pressure pump is disclosed. The pump uses a wobble plate design with dynamically variable tilt to provide continuous adjustment of pump stroke length and output. Dynamically variable tilt is accomplished using a linearly actuated tilt thruster rotationally coupled to the drive shaft to maintain a selected tilt of the wobble plate through the rotation of the wobble plate.
Patent WO-2020219865-A1 (WO)
Inventor: WALKER MATTHEW
IPC: G06T5/50
Filed: 2020-04-24
Abstract: A system and method for tracking the movement of a recording device to form a composite image is provided. The system has a user device with a sensor array capturing motion data and velocity vector data of the recording device when the recording device is in motion, an attachment member for coupling the user device to the motion capturing device, and a server with program modules. The program modules described are a calibration module for calibrating a position of the user device relative to a position of a lens of the recording device, a recorder module for receiving the motion data and velocity vector data from the sensor array; and a conversion module for combining the position of the user device relative to the lens of the recording device, and the motion data and velocity vector data and transforming the data into a file that is usable by a compositing suite, a three-dimensional application, or both.
Patent WO-2020227322-A1 (WO)
Title: Esteramine compositions
Inventor: FAUNCE JAMES A
IPC: C11C3/08
Filed: 2020-05-05
Abstract: Compositions comprising at least one esteramine active are disclosed in which the esteramine provides conditioning, softening, and/or cleaning properties. The compositions are useful for hair care, as well as in other applications, such as cleaning compositions, fabric softening compositions, and skin care compositions. Also disclosed are esteramine compositions that comprise a synergistic mixture of at least one esteramine and mono- and di-glycerides that provides better wet and dry combing than either the esteramine or mono- and di-glycerides alone. The synergistic mixture comprises about 50% to about 90% by weight esteramines and about 10% to about 50% by weight mono- and diglycerides.
Patent WO-2021006948-A1 (WO)
Title: Fiber optic noise mitigation for distributed acoustic sensing
Inventor: WILLIS MARK ELLIOTT
IPC: E21B47/002
Filed: 2020-05-13
Abstract: To mitigate zigzag noise and increase the quality of data provided from DAS VSP in wells with significant vertical sections, zigzag noise characteristics are identified and quantified. The zigzag noise properties can be extracted from an analysis of an autocorrelation of DAS VSP traces. The zigzag noise has a characteristic time period or repeat time delay that is the time period for the noise to propagate along the wireline through a zone of the wellbore with poor acoustic coupling between the fiber optic cable and formation. This period can be identified from analysis of the autocorrelation referred to herein as a crosswise lag summation function. The crosswise lag summation function identifies groups of DAS data traces containing zigzag noise and outputs zigzag noise periodicity for each group of traces. Once it has been identified, the zigzag noise can be removed from the VSP data and improve formation evaluation.
Patent WO-2021101589-A1 (WO)
Inventor: COULOMBE GREGORY KENNETH
IPC: G06F40/30
Filed: 2020-05-21
Abstract: Aspects of the present disclosure provide techniques for intent matching. Embodiments include receiving input of text by a user via a user interface. Embodiments include determining weights for portions of the text based on a plurality of keywords. Embodiment include generating an embedding of the text. Embodiments include determining an intent of the text by weighting, based on the weights, word mover's distances from the embedding of the text to a known embedding of known text associated with the intent in order to determine a similarity measure between the text and the known text. Embodiments include providing content to the user via the user interface based on the intent.
Patent WO-2020243104-A1 (WO)
Title: Systems and methods for treating incontinence
Inventor: RONDONI JOHN
IPC: A61N1/36
Filed: 2020-05-26
Abstract: A system and/or method to treat incontinence of a patient includes a stimulation element implanted to stimulate one or more target sites to activate an external sphincter or other mechanism of continence of the patient, such as the external urethral sphincter and/or the external anal sphincter.
Patent WO-2020243726-A1 (WO)
Inventor: SHAHVIRDI DIZAJ YEKAN TAHA
IPC: H01Q13/08
Filed: 2020-06-01
Abstract: Examples disclosed herein relate to reflectarray antenna for enhanced wireless applications. The reflectarray antenna has a ground conductive plane, a dielectric substrate coupled to the ground conductive plane, and a patterned conductive plane coupled to the dielectric substrate and comprising an array of cells to generate an antenna gain. In some aspects, each cell in the array of cells includes a reflector element with a predetermined custom configuration and configured to receive a radio frequency (RE) signal and to generate an RE return beam at a predetermined direction. Other examples disclosed herein relate to a portable reflectarray and a method of fabricating a reflectarray antenna.
Patent WO-2021055051-A1 (WO)
Title: Minimization function for friction solving
Inventor: MITROVIC PETAR
IPC: G06T13/20
Filed: 2020-06-18
Abstract: A physics engine executed on a processor to simulate real-time rigid body dynamics of a simulated physical system with a minimizing function between initial velocities and intermediate solver velocities is provided. The physics engine may be configured to iteratively loop through a collision detection phase, an iterative solving phase, updating phase, and display phase. The physics engine may be configured to store initial velocities for colliding pairs of bodies. The physics engine may be further configured to determine intermediate solver velocities for the colliding pairs of bodies based on accumulated results of constraint solving for each pair of bodies. The physics engine may be further configured to calculate friction velocities for that colliding pair of bodies based on the stored initial velocities and the intermediate solver velocities using a minimization function, and apply a friction force or impulse based on the calculated friction velocities.
Patent WO-2020263787-A1 (WO)
Title: Network security system and method for preemptively identifying or remediating security vulnerabilities
Inventor: SIDDIQ IRSLAN
IPC: G06F21/55
Filed: 2020-06-23
Abstract: A system, a method, and a computer program for analyzing network security data from diverse data sources to predict and remediate a vulnerability at a node in a computer network, comprising receiving network security data from a plurality of data sources, extracting feature vectors from the received network security data, applying a machine learning model to the extracted feature vectors to generate a weighted vulnerability value, predicting a computing resource vulnerability at a node in the computer network based on the weighted vulnerability value, and transmitting the predicted computing resource vulnerability to a computing device which is configured to remediate the predicted computing resource vulnerability.
Patent WO-2020264301-A1 (WO)
Inventor: ROSS MATTHEW
IPC: A61C7/18
Filed: 2020-06-26
Abstract: Devices and methods for intermaxillary fixation are disclosed. Devices comprise a plurality of dental bands, positioned around a tooth or teeth, a dental clamp affixed to an external face of the dental band, and at least one attachment for connecting two or more dental bands and providing fixation of the maxilla/mandible complex. The intermaxillary fixation devices can be easily applied to a tooth or a plurality of teeth, and do not require attachment to the gums and/or penetration into bone.
Patent WO-2021007122-A1 (WO)
Title: Unified harq id for multiple frequency channels
Inventor: ZHOU YAN
IPC: H04L1/18
Filed: 2020-07-03
Abstract: In one aspect, a method of wireless communication includes transmitting, by a wireless communication device, a negative acknowledgement message (NACK) for a first Physical Downlink Shared Channel (PDSCH) via a first frequency band; and receiving, by the wireless communication device, a second PDSCH via a second frequency band, wherein the first frequency band is different from the second frequency band. Other aspects and features are also claimed and described.
Patent WO-2021034506-A1 (WO)
Title: Reformer assembly
Inventor: SCHOLEY IAN KENNETH
IPC: B21D22/20
Filed: 2020-08-06
Abstract: A base reformer assembly (100), and/or a base reformer roller die unit (130), includes a generally toroid chuck (132), a roller die (134), and a roller die unit actuating assembly (250). The roller die (134) is movably disposed within the chuck (132). The roller die unit actuating assembly (250) is structured to actuate the roller die (134). The roller die unit actuating assembly (250) is operatively coupled to the roller die (134). Further, all elements of the roller die unit actuating assembly (250).
Patent WO-2021112927-A1 (WO)
Title: Compositions de protéines anti-vegf et procédés de production associés
Inventor: TUSTIAN ANDREW
IPC: C07K1/18
Filed: 2020-08-18
Abstract: La présente divulgation concerne des compositions comprenant des protéines anti-VEGF et des procédés de production de telles compositions.
Patent WO-2021046190-A1 (WO)
Title: Cystathionine beta-synthase enzyme therapy for treatment of elevated homocysteine levels
Inventor: SELLOS-MOURA MARCIA
IPC: A61K38/51
Filed: 2020-09-03
Abstract: The present disclosure provides methods for treating homocystinuria or elevated homocysteine levels in subjects, including methods of improving cognitive function and ameliorating skeletal fragility, and methods of stratifying patient populations to determine disease progression or severity and/or to determine treatment regimens. In some embodiments, the methods of improving cognitive function in a subject having elevated total plasma homocysteine (tHcy) levels further comprise providing a cognitive or behavioral intervention.
Patent WO-2021046443-A1 (WO)
Inventor: DHANASEKHARAN KUMAR
IPC: C12M1/00
Filed: 2020-09-04
Abstract: L'invention concerne des procédés de production, de capture et de purification continues d'agents biologiques tels que des protéines recombinantes. Des compositions pharmaceutiques contenant de tels agents biologiques, ainsi que des méthodes de traitement et des utilisations desdits agents biologiques sont en outre décrites.
Patent WO-2021046560-A1 (WO)
Title: Aircraft fuselage configurations for avoiding tail strike while allowing long payloads
Inventor: REWERTS SCOTT
IPC: B64C1/14
Filed: 2020-09-08
Abstract: A fixed-wing cargo aircraft having a kinked fuselage to extend the useable length of a continuous interior cargo bay while still meeting a tailstrike requirement is disclosed, The fuselage defines a continuous interior cargo bay along a majority of its length and a pitch axis about which the cargo aircraft rotates during takeoff while still on the ground. The fuselage includes a forward portion defining longitudinal-lateral plane of the cargo aircraft an aft portion extending aft from the pitch axis to the aft end and containing an aft region of the continuous interior cargo bay that extends along a majority of a length of the aft portion. The aft portion has a centerline extending above the forward upper surface of the aircraft.
Patent WO-2021067827-A1 (WO)
Inventor: O'BOYLE BRENDAN
IPC: A61K31/437
Filed: 2020-10-02
Abstract: The present disclosure provides compounds, such as compounds of Formula I, and compositions that are MCL1 inhibitors.
Patent WO-2021080833-A1 (WO)
Title: Dynamically changing a fiducial marker for iot device identification
Inventor: AMADIO LOUIS
IPC: G06K19/06
Filed: 2020-10-15
Abstract: The techniques described herein enable a head-mounted display device to use a fiducial marker to identify an Internet of Things (IoT) device. The head-mounted display device can use the identifier to establish a network connection with the IoT device. For example, the identifier can include an Internet Protocol (IP) address, a Bluetooth address, a cloud IoT identifier (e.g., AZURE hub IoT identifier), or another type of an identifier. By using an electronic paper display, the IoT device can dynamically generate and display a new fiducial marker when a new identifier is assigned to the IoT device or is generated by the IoT device. Consequently, the head-mounted display device can detect the fiducial marker and extract the identifier for the IoT device from the fiducial marker so that the identifier can be used to establish a network connection with the IoT device.
Patent WO-2021086681-A1 (WO)
Inventor: WOOD CHARLES E
IPC: A61B18/00
Filed: 2020-10-20
Abstract: A reusable cable connecting a surgical device to a therapy generator can include a memory device to track the surgical devices that have been used with the cable. When the cable is coupled to the therapy generator, a control circuit in the therapy generator can interrogate the cable and read data stored in the memory device of the cable, where the data represents a number of surgical devices previously coupled to the cable.
Patent WO-2021087248-A1 (WO)
Inventor: RABUKA DAVID
IPC: C07D405/12
Filed: 2020-10-30
Abstract: La présente invention concerne des structures conjuguées anticorps anti-CD37-maytansine. L'invention concerne également des méthodes de production de ces conjugués, ainsi que des méthodes d'utilisation de ceux-ci.
Patent WO-2021097101-A1 (WO)
Title: Systems and methods for synthesis of zsm-22 zeolite
Inventor: AL-SHAFEI EMAD
IPC: B01J19/12
Filed: 2020-11-12
Abstract: Systems and methods for production of consistently- sized ZSM-22 zeolite catalyst crystals, a method including preparing an aluminate solution; preparing a silica solution; mixing the aluminate solution and the silica solution to form a zeolite-forming solution; heating the zeolite solution with microwave irradiation in a first, a second, a third, and a fourth distinct isothermal stage to produce the consistently- sized ZSM-22 zeolite catalyst crystals within a pre-selected crystal size range using a non-ionic surfactant.