baber/WOPTO huggingface dataset:
Patent PT-1100829-E (PT)
Title: Use of basiliximab in the treatment of rheumatoid arthritis or skin diseases
Inventor: AMLOT PETER LLOYD
IPC: A61P17/08
Filed: 1999-07-26
Abstract: Use of a CD25 binding molecule which comprises at least one antigen binding site comprising at least one domain which comprises in sequence, the hypervariable regions CDR1, CDR2 and CDR3; said CDR1 having the amino acid sequence Arg-Tyr-Trp-Met-His, said CDR2 having the amino acid sequence Ala-Ile-Tyr-Pro-Gly-Asn-Ser-Asp-Thr-Ser-Tyr-Asn-Gln-Lys-Phe-Glu-Gly, and said CDR3 having the amino acid sequence Asp-Tyr-Gly-Tyr-Tyr-Phe-Asp-Phe, in the treatment of rheumatoid arthritis or inflammatory or hyperproliferative skin diseases.
Patent SG-192-G (SG)
Title: Juice-extracting mill roll
IPC: C13B10/02
Filed: 1992-01-02
Abstract: The roll 20 has a plurality of axially-extending juice channels 23 and juice inlet passages 25 extending from the surface of the roll, in this case having grooves 24, into the channels 23. Each passage 25 is in the form of an axially-extending slit in the roll body 22 and has an extension 29 projecting into the channel 23 to form a juice trap 30. Alternatively the juice trap is formed by each inlet passage intersecting the respective juice channel at a leading or lagging portion of the juice channel relative to the direction of rotation of the roll, and the opposite lagging or leading portion of the juice channel being shut off from the juice inlet passage.
Patent SG-93190-G (SG)
Title: Wire for bonding a semiconductor device
IPC: H01L23/49
Filed: 1990-11-17
Abstract: An inexpensive, very fine wire of high-purity copper is disclosed as an alternative to the fine gold wire which is currently used in the bonding of semiconductor devices. The very fine wire of high-purity copper is prepared from a copper ingot that contains 0-2 ppm of S, 0-2 ppm of Ag, 0-1 ppm of Se and 0-1 ppm of Te as incidental impurities with the total content of these and any other incidental impurities present being held at a level not exceeding 10 ppm. By subjecting it to an appropriate heat treatment, the wire acquires an elongation of 5-22%, a breaking strength of 14-33 kg/mm2, and a Vickers hardness of 38-50, the latter value being measured with respect to said high-purity copper in an ingot form. By reducing the amounts of these impurities to even lower levels, very fine wires are obtained that can be used in the bonding of a semiconductor device without abnormally shaped loops being formed or wire breakage being experienced and the characteristics of the wires can be adapted to specific conditions of use by performing an appropriate heat treatment.
Patent IE-32961-L (IE)
Title: 2-alkoxy-3, 5-dihalobenzene alkylaminoalkyl ethers
IPC: C07D295/08
Filed: 1969-02-11
Abstract: 1,251,695. Aminoalkyl ethers of 2-(alkoxy) - 3,5-dihalobenzenes. SOC. D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE. 13 Feb., 1969 [16 Feb., 1968; 10 May, 1968], No. 7933/69. HeadingC2C. Novel compounds of the Formula (I) and their acid-addition salts with a mineral or organic acid and their quaternary ammonium salts, wherein n and m each is 0, 1 or 2, R, R l and R 2 each is H or C 1-5 alkyl, R 3 is C 1-5 alkyl, or the group NR 1 R 2 represents a heterocyclic radical, and X and Y are halogens, are obtained by acetylating a monoether of pyrocatechol, then halogenating the product, de-acetylating the halogenated product and treating the dihalo-pyrocatechol monoether with an appropriate (substituted amino) alkyl chloride, and optionally forming acid or quaternary ammonium salts. Pharmaceutical compositions, useful as spasmogenie agents, contain compounds of Formula (I) above as active ingredients, and may be formulated as tablets or solutions.
[GB1251695A]
Patent IE-890275-L (IE)
Title: Pharmaceutical composition for 4-aroylimidazol-2-ones
IPC: A61K31/415
Filed: 1989-01-27
Abstract: The present invention provides a liquid pharmaceutical composition comprising a) an effective amount of a 4-aroylimidazol-2-one, or a pharmaceutically acceptable salt thereof, and b) one or more pharmaceutically acceptable nonionic surfactants in an amount from about 30% to about 99% by weight of the composition, and optionally further comprises one or more pharmaceutically acceptable excipients other than nonionic surfactants in a total amount up to about 45% by weight of the composition.
[EP0326103A1]
Patent IE-820703-L (IE)
Title: Lyophilized preparation of a penicillin derivative
IPC: A61P31/04
Filed: 1982-03-25
Abstract: Preparation of a pharmaceutical parenteral dosage unit of a lyophilized penicillin derivative in which the penicillin derivative is dissolved in water to a concentration of 100-135 mg/ml, as compared to the standard concentration of 200 mg/ml. The solution is then filled into a container and lyophilized by known techniques. The product is a light, fluffy lyophilized product which upon reconstitution will go into solution rapidly and completely even at the high concentration of 400 mg/ml.
[GB2095551A]
Patent FI-810261-L (FI)
Inventor: WIDMER EUGEN
IPC: G05B9/03
Filed: 1981-01-29
Abstract: 1. A device for monitoring a wheel-revolution transmitter of a vehicle, and particularly of a rail vehicle, which device is provided with a first pulse transmitter (S1) for generating a first wheel-revolution-proportional pulse sequence and with a second pulse transmitter (S2) for generating a second wheel-revolution-proportional pulse sequence which is phase-shifted with respect to the first pulse sequence, characterized in that two first and two second, clocked memory flip-flops (Sp1, Sp2 and Sp3, Sp4 respectively) are provided, that one pulse transmitter (S1) is connected to the clock inputs (2) of the two first clocked memory flip-flops (Sp1, Sp2) and to the data inputs (1) of the two second clocked memory flip-flops (Sp3, Sp4),that the other pulse transmitter (S2) is connected to the clock inputs (2) of the two second clocked memory flip-flops (Sp3, Sp4) and to the data inputs (1) of the two first clocked memory flip-flops (Sp1, Sp2), an inverter (l1, l2) being arranged in each case in front of each one of the two clock inputs (20) of the first and second clocked memory flip-flops (Sp1, Sp2, Sp3, Sp4), and that one output (3) of in each case one of the two first and of the two second clocked memory flip-flops (Sp2 and Sp4) and the negated output (4) of in each case the other first and second clocked memory flip-flop (Sp1 nd Sp3) are connected in each case to a comparator (G1, G2).
Patent FI-822697-L (FI)
Inventor: KARDYS JOSEPH ANTHONY
IPC: C07D277/20
Filed: 1982-08-02
Abstract: A novel compound of empirical formula  C9H7N2O5SRR<1>Z (I)  produced by reacting an ester of the formula <CHEM> with an equimolar amount of an amine of the formula ZNH2 in a reaction inert organic solvent at a temperature of from about 0 to 110 DEG C wherein R is hydrogen benzyl or (C1-C3) alkyl; R<1> is benzyl or (C1-C4) alkyl and Z is benzopyronyl, alkyl substituted benzopyronyl, 2-pyridyl, alkyl substituted-2-pyridyl, 2-thiazolyl, 2-thiazolyl substituted by one or two alkyl group, or 5-alkyl-3-isoxazolyl, each alkyl having from one to four carbon atoms; and a novel process utilizing the compounds of formula (I) as intermediates for production of known anti-inflammatory agents of the formula <CHEM> u
Patent FI-850518-L (FI)
Inventor: CARDINAL JOHN ROBERT
IPC: A61K9/22
Filed: 1985-02-07
Abstract: Laminate device for the controlled and prolonged release of at least one active agent to an ambient environment comprising at least one core sheet, said core sheet or sheets comprising said agent or agents in a polymer matrix, and, in a preferred embodiment, a porosity enhancing agent in admixture with said agent; said core sheet or sheets being alternately sandwiched or interposed between coextensive inert polymeric films substantially impermeable to said environment and to said agenit or agents, said device being perforated by one or a plurality of macroholes extending through said sheets and said films. In a modification of said device the perimeter edge thereof is coated by an inert polymeric film substantially impermeable to said environment and to said agent or agents. Also included are methods for making such a device.
Patent IE-881025-L (IE)
Title: Road manhole
IPC: E02D29/14
Filed: 1988-04-06
Abstract: A manhole assembly includes a circular cover 4 seated in a frame 1 and removably hinged thereto by a T-shaped lug 16 extending radially from the cover and lying within a matingly configured receptacle 5 defined in an upper edge of the frame. Lips 9 overhang opposite interior ends of the deepened receptacle trough 7 to restrain the pivot shaft 18 of the lug against vertical removal with the cover closed, in which position the lug has no contact with the receptacle surfaces to avoid clanking noise upon the passage of a vehicle.
[US4840514A]
Patent IE-36605-L (IE)
Title: Lightweight building element
IPC: E04C2/20
Filed: 1972-07-26
Abstract: 1396426 Laminates F HAARBURGER 18 July 1972 [3 Aug 1971] 33435/72 Heading B5N [Also in Division E1] A lightweight building element comprises a sealed envelope 10 of a high tensile dimensionally stable flexible material 11, 12 comprising a textile web of synthetic plastics yarn coated on both sides with elastomer and/or plastomer and/or duromer plastics and a filling 14 of synthetic foam. In the embodiment shown, the element has a rectangular shape 15 made of metal or wood or synthetic plastics material, the frame having a U-shaped cross-section and being provided with clamps 16 between which the outer envelope 10 is clamped and held in the frame 15 along the edges 13. The element may be made by welding the sheets 11, 13 along their edges and pumping foam-forming components into the resultant envelope. In a preferred embodiment, the material of the envelope may incorporate steel wires. The elements can be combined to build as illustrated in Fig. 2 (not shown), inner and outer walls of light construction, the elements being joined by light replaceable joining elements.
[GB1396426A]
Patent IE-811139-L (IE)
Title: Imidazo-rifamycin derivatives
IPC: C07D498/22
Filed: 1981-05-21
Abstract: New rifamicyn derivatives of the following general formula <IMAGE> I wherein: A may be the structure <IMAGE> -x- is a chemical bond or nil; R is hydrogen or acetyl R1 and R2 independently represent hydrogen, (C1-4) alkyl, benzyloxy, mono- and di-(C1-3)alkylamino- (C1-4)alkyl, (C1-3)alkoxy- (C1-4)alkyl, hydroxymethyl, hydroxy-(C2-4)-alkyl, nitro or R1 and R2 taken together with two consecutive carbon atoms of the pyridine nucleus form a benzene ring optionally substituted by one or two methyl or ethyl groups; R3 is a hydrogen atom or nil; with the proviso that, when A is A1, -x- is nil and R3 is a hydrogen atom; with the further proviso that, when A is A2, -x- is a chemical bond and R3 is nil. The compounds possess antibacterial utility.
[US4341785A]
Patent IE-35645-L (IE)
Title: New sulphonic acid esters, their preparation and their¹medicinal use
IPC: C07D241/04
Filed: 1971-09-16
Abstract: 1342538 1,4 - Bis - (sulphonyloxy - propionyl)-piperazines BAYER AG 16 Sept 1971 [18 Sept 1970] 43210/71 Heading C2C Novel compounds I where A and A<SP>1</SP> are H or aliphatic groups, X and Y are H, halogen, CN, MeSO 2 , -SCN, -OCN, -NCO or -N 3 and Z is halogen, CN, MeSO 2 , -SCN, -OCN, -NCO or -N 3 are made by reacting (X)(Y)(Z)CSO 3 .M with an appropriate 1,4-bis-(3-iodopropionyl)-piperazine (M is an equivalent of a mono- or di-valent cation which forms a sparingly soluble iodide). Pharmaceutical preparations exhibiting, in particular, cytostatic action and useful in combating lymphatic leukaemia contain (I) as active ingredient. Administration may be, e.g. orally or parenterally.
[GB1342538A]
Patent IE-32402-L (IE)
Title: Draining cheese curds to form cheese
IPC: A01J25/11
Filed: 1968-10-01
Abstract: 1,203,670. Cheese curds. H. KOOPMANS. 3 Oct., 1968 [4 Oct., 1967], No. 46972/68. Heading A2B. A method of draining cheese curds to form cheese comprises the steps of providing a vessel having at least one vertical perforated pipe disposed therein, and a venting duct filling the vessel with whey so as to vent any air present, supplying the contents of a cheese vat or and container into the pipe or pipes such that the curds are deposited therein, the whey being expelled via the perforations and flowing through the venting duct so that no air can enter, draining the remaining whey through an outlet duct, and removing the drained curd from the pipe or pipes by opening the lower end thereof to allow the curd to sink out and into an associated mould provided therebelow. The curds may be compressed in the pipe after removal of whey from the vessel by a piston.
[GB1203670A]
Patent IE-791210-L (IE)
Title: OCTAHYDRO-2H-PYRROLO (3,4-g) QUINOLINES
IPC: C07D471/04
Filed: 1979-08-08
Abstract: Octahydro-2H-pyrrolo[3,4-g]quinolines, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinsonism, are described herein. These novel compounds are prepared by reacting a 2-alkylcarbonyloctahydro-2H-pyrrolo[3,4-g]quinoline with base.
[EP0013788A1]
Patent IE-39713-L (IE)
Title: Defogging rear window for motor vehicles
IPC: H05B3/84
Filed: 1974-06-18
Abstract: A defogging and defrosting rear window pane for motor vehicles has a plurality of spaced heating elements embedded therein. A relatively short metallic collector having a circular segment configuration is provided in each peripheral side of the window pane at opposite margins thereof. The central heating element extends between the collectors in a rectilinear path. Additional heating elements above and below the central element have a rectilinear central portion parallel to the central element and are connected to the collectors by end portions converging on the respective collectors. The respective collectors have an appendix extending outwardly beyond the window weatherstripping to serve as a terminal for connection to a power source.
[US3995142A]
Patent IE-34676-L (IE)
Title: BENZIMIDAZO [2, 1-b] QUINAZOLINE DERIVATIVES AS¹IMMUNOSUPPRESSANTS
IPC: C07D235/24
Filed: 1970-11-02
Abstract: Benzimidazo [2,1-b]quinazolin- 12(6H)ones, immunosuppressives and agents for treatment of auto-immune diseases, are prepared via (1) reacting a 2-chlorobenzimidazole with an anthranilic acid or ester; (2) reacting a 2-aminobenzimidazole with an anthranilic acid or ester in the presence of trifluoroacetic acid or (3) reacting a 2-methylmercaptobenzimidazole with an anthraniloyl halide hydrohalide.
[US3669969A]
Patent IE-34714-L (IE)
Title: Morpholine derivatives.
IPC: C07D265/32
Filed: 1970-11-10
Abstract: 1295447 Compositions comprising morpholine derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 9 Nov 1970 [17 Nov 1969] 56086/69 Addition to 1138405 Heading A5B [Also in Division C2] Pharmaceutical compositions useful in the treatment of anxiety and neurotic states and for the treatment or prophylaxis of depressive illness comprise, in admixture with a suitable diluent as carrier, a compound I in which R<SP>1</SP> is H, alkyl, alkenyl, or cycloalkyl; R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> are H or alkyl, at least one being alkyl; or R<SP>2</SP> and R<SP>3</SP> together with the two adjacent carbon atoms form a cycloalkane ring and R<SP>4</SP> is H or alkyl; and X is an optionally substituted aryl radical. The compositions may be administered orally or parenterally. Other ingredients present may include neuroleptic agents, other sedatives and tranquillisers, anticonvulsants, #-adrenergic blocking agents, anti-Parkinson drugs, other antidepressants and monoamine oxidase inhibitors.
[GB1295447A]
Patent IE-38282-L (IE)
Title: Pyrotechnic composition
IPC: B60R21/26
Filed: 1973-09-25
Abstract: A gas-generating pyrotechnic composition comprises:
[US3912561A]
Patent IE-821757-L (IE)
Title: Packages for enclosing semiconductor elements
IPC: H01L23/12
Filed: 1982-07-22
Abstract: PURPOSE:To prevent handling-caused insulator breakdown in a semiconductor without using an insulating coating by a method wherein the middle portion of a package side wherein the end faces of wirings are exposed is formed into a recess enclosed by the edges of the package side. CONSTITUTION:The end faces of plating wirings 30 belonging in the package layers, connecting an inner pattern 24a to terminal pins 16, are exposed on a side of a semiconductor element package 20. The middle portion of said side of the semiconductor element package 20 is caused to form a recess inside both edges 20a and 20b, whereinto the plating leads 30 collect together.
[JP58016552A]
Patent IE-781882-L (IE)
Title: Silvering concentrates.
IPC: C09K15/06
Filed: 1978-09-18
Abstract: Potentially explosive mixtures which can form as a result of accidental contact between a concentrated aqueous solution of ammoniacal silver salt and a concentrated solution of a strong alkali are inhibited in an improved multi-part system for electroless deposition of silver on an activated surface by simultaneous admixture of the diluted parts thereupon. Accordingly, an improved method for inhibiting formation of explosive conditions and compounds in a mixture formed by contacting concentrated aqueous ammoniacal silver salt and a concentrated solution of alkali is provided, whereby an effective amount of an explosion inhibitor is provided either in combination with the ammoniacal silver salt, in which case sufficient extraneous ammonium ions are provided to stabilize the explosion inhibitor, or in the strong alkali, or a portion of the explosion inhibitor is provided in each of said ammoniacal silver salt and strong alkali. Conventional reducers for ammoniacal silver salt can be utilized together with said explosion inhibitor.
[US4192686A]
Patent IE-40040-L (IE)
Title: Dimethyl terephthalate
IPC: C07C69/82
Filed: 1974-10-01
Abstract: Disclosed is an improvement in the cooxidation process for making dimethyl terphthalate (DMT). In the cooxidation process an oxidate comprising monomethyl terephthalate and p-toluic acid is esterified with methanol to form a reaction mixture comprising DMT and methyl p-toluate, methyl p-toluate is separated from the reaction mixture, and p-xylene and said methyl p-toluate are cooxidized in the liquid phase with molecular oxygen to form more oxidate, which is esterified, etc. The improvement comprises separating p-toluic acid from part of the oxidate prior to esterifying the oxidate, and cooxidizing separated p-toluic acid with said p-xylene and said methyl p-toluate. This improvement results in a lesser quantity of oxidate subjected to esterification, and a reduction in the quantity of methyl p-toluate cooxidized with p-xylene.
[US3956362A]
Patent IE-43775-L (IE)
Title: Metered dispensing of liquids
IPC: B67B7/48
Filed: 1976-10-06
Abstract: A container for metered dispensing of liquid. The container in an inverted orientation is connected at its withdrawal and venting aperture to an electromagnetically actuated metering valve, wherein the metering valve has a movable valve element. Within the inverted container there is a cup-shaped vessel having a tear-off cover which simultaneously forms the closure of the container and has its rim sealingly connected to the rim of the withdrawal and venting aperture.
[US4109829A]
Patent IE-42057-L (IE)
Title: Ó-(ureido or thioureido) benzyl or cyclohexadienyl methyl¹penicillins
IPC: C07D499/68
Filed: 1975-10-24
Abstract: Penicillins of the formula <IMAGE> wherein X is O or S; Y is H or alkyl; Z is <IMAGE> R1 is H or OH; and R2 and R3 each are H or wherein X is O or S; Y is H or alkyl; R2 and R3 each are H or taken together with the carbons to which they are attached form an aromatic six-membered carbocyclic or N-heterocyclic ring and alkyl, alkoxy, dialkylamino or halogen derivatives thereof are active against Gram-positive and Gram-negative bacteria.
[US4031230A]
Patent IE-792360-L (IE)
Title: 1,3,4-thiadiazoles
IPC: A01N43/82
Filed: 1979-12-07
Abstract: 1,3,4-thiadiazole-2-carboxylic acid derivatives of the formula <IMAGE> I wherein R is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkinyl or C3-C6-cycloalkyl, R1 is C1-C6-alkoxycarbonyl, aminocarbonyl, C1-C8-alkylaminocarbonyl, C3-C6-cycloalkylaminocarbonyl, di-C1-C8-alkylaminocarbonyl, cyclohexylmethylaminocarbonyl, alkoxyalkylaminocarbonyl, morpholinocarbonyl, pyrrolidinocarbonyl, piperidinocarbonyl or cyano, and n is 0.1 or 2.
[US4279907A]
Patent NO-821436-L (NO)
Inventor: GROT WALTHER GUSTAV
IPC: C25B13/08
Filed: 1982-04-30
Abstract: A process is provided for making a liquid composition of a perfluorinated polymer having sulfonic acid or sulfonate groups in a liquid medium by contacting the polymer with a mixture of 25 to 100% by weight of water and 0 to 75% by weight of a second liquid component such as a lower alcohol, e.g., propanol or methanol, at a temperature of at least 180 DEG  C. (at least 240 DEG  C. when about 90% to 100% water is used), in a closed system. The liquid composition made by this process, or modified liquid products prepared therefrom, are used in coating various substrates, in casting films, and in repairing perfluorinated ion exchange films and membranes. The process is also useful in recovering perfluorinated polymer having sulfonic acid or sulfonate groups from scrap and used articles made of such polymer or containing such polymer as a component part thereof.
Patent NO-822156-L (NO)
Inventor: MEYER FRITZ
IPC: H04B3/36
Filed: 1982-06-25
Abstract: 1. A regenerator for digital signals with quantized feedback to restore signal components which are suppressed in the transmission of the digital signals, with a decision device (E) which can contain a time decision device in addition to an amplitude decision device, and whose amplification cut-off frequency corresponds approximately to the highest signal frequency, and with a connection from the decision device output to a first adder circuit (S1) which precedes the decision device in the signal path, in particular for multi-stage digital signals, characterised in that the output of the decision device (E) is connected to the first input of a second adder circuit (S2) whose second input is connected to the output of a delay stage (VS) with a delay time which corresponds approximately to the signal transit time through the decision device (E), and with a phase rotation of 180 degrees, and that the input of the delay stage (VS) is connected in parallel with the input of the first adder circuit (S1) for the signals which are to be regenerated.
Patent NO-872304-L (NO)
Inventor: TAYBL CHRISTA
IPC: H02B1/06
Filed: 1987-06-02
Abstract: The invention relates to a casing, particularly a junction box casing (1) for telecommunications engineering, consisting of a box-shaped base (24), a cover (9) to close this, and a packing ring (14). According to the invention, upper and lower guide elements (2, 25) are provided, each of which consist of a pin (8, 13) on the inner sides of the side walls (27) of the cover (9) and of a pin guide (36, 37) on the outer walls (26) of the base (24). The pin guides (36, 37) are inclined at an acute angle to the base surface (28) of the base (24) and are directed toward the rear wall (30) of the base (24).