baber/WOPTO huggingface dataset:
Patent DE-69531603-D1 (DE)
Inventor: MC DONALD A
IPC: A61P29/00
Filed: 1995-10-16
Granted: 2003-10-02
Abstract: In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds may act as agonists, partial agonists, antagonists or allosteric modulators of acetylcholine receptors, and are useful for a variety of therapeutic applications, such as the treatment of Alzheimer's disease and other disorders involving memory loss and/or dementia (including AIDS dementia); disorders of attention and focus (such as attention deficit disorder); disorders of extrapyramidal motor function such as Parkinson's disease, Huntington's disease, Gilles de la Tourette syndrome and tardive dyskinesia; mood and emotional disorders such as depression, panic, anxiety and psychosis; substance abuse including withdrawal syndromes and substitution therapy; neuroendocrine disorders and dysregulation of food intake, including bulimia and anorexia; disorders of nociception and control of pain; autonomic disorders including dysfunction of gastrointestinal motility and function such as inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, gastric acid secretion and ulcers; pheochromocytoma; cardiovascular dysfunction including hypertension and cardia arrhythmias, comedication in surgical procedures, and the like.
Patent DE-69532921-D1 (DE)
Inventor: BENJAMIN NIGEL
IPC: A61K33/14
Filed: 1995-02-17
Granted: 2004-05-27
Abstract: The invention relates to the use of acidified nitrite as an antimicrobial agent and describes a dosage form for use in the treatment of bacterial, viral or fungal conditions. The dosage form may be in any pharmaceutically acceptable carrier means and comprises an acidifying agent adapted to reduce the pH at the environment. Amongst the many potential applications for the invention, the inventive composition has been shown to be particularly effective as an animal feed supplement, and as an agent for sterilising objects. Compositions and methods of use for these applications are described.
Patent DE-69604781-D1 (DE)
Inventor: MUELLER ACHIM
IPC: B29C39/02
Filed: 1996-01-22
Granted: 1999-11-25
Abstract: PCT No. PCT/EP96/00244 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Jan. 22, 1996 PCT Pub. No. WO96/23648 PCT Pub. Date Aug. 8, 1996For the fast and rational manufacture of moulded articles, specifically contact lenses, that are partly colored or have regions of different colors, by the casting process, measured amounts of two or more crosslinkable materials of different colors are introduced into the casting mould in the uncrosslinked stated unmixed and, after closing the casting mould, are crosslinked together. By suitably controlling the introduction of the different crosslinkable materials with regard to location and/or time the merging of the colors and the transitions between the colors in the contact lens are influenced in a controlled manner.
Patent DE-69606707-D1 (DE)
Inventor: LIGHT R
IPC: C07K1/14
Filed: 1996-06-05
Granted: 2000-03-23
Abstract: A method for separating unmodified hemoglobin from cross-linked hemoglobin in a hemoglobin solution. The method involves contacting the hemoglobin solution with a least one dissociating agent to form a dissociation solution wherein unmodified tetrameric hemoglobin is dissociated to form hemoglobin dimers. The hemoglobin dimers are then separated from the dissociation solution, while retaining the cross-linked hemoglobin in the dissociation solution.
Patent DE-69608701-D1 (DE)
Inventor: CALVERLEY JOHN
IPC: A61K31/00
Filed: 1996-12-02
Granted: 2000-07-06
Abstract: PCT No. PCT/DK96/00502 Sec. 371 Date Jan. 8, 1998 Sec. 102(e) Date Jan. 8, 1998 PCT Filed Dec. 2, 1996 PCT Pub. No. WO97/20811 PCT Pub. Date Jun. 12, 1997The present invention relates to compounds of formula (I) in which formula X is hydrogen or hydroxy; R1 and R2 stand for methyl or ethyl, or, when taken together with the carbon atom bearing the group X, can form a C3-C5 carbocyclic ring; Q is either a single bond or a C1-C8 hydrocarbylene in which one of any methylene groups not directly bonded to the carbonyl group may optionally be replaced by an oxygen atom (or methyl by hydroxy); Y is either a single bond or C1-C8 hydrocarbylene; and derivatives of (I) in which one or more of the hydroxy groups are masked as groups which can be reconverted to hydroxy groups in vivo. The compounds show anti-inflammatory and immunomodulating effects as well as strong activity in inducing differentiation and inhibiting undesirable proliferation of certain cells.
Patent DE-69617030-D1 (DE)
Inventor: GUSTAFSSON STIG
IPC: A23G3/12
Filed: 1996-08-20
Granted: 2001-12-20
Abstract: PCT No. PCT/SE96/01027 Sec. 371 Date May 11, 1998 Sec. 102(e) Date May 11, 1998 PCT Filed Aug. 20, 1996 PCT Pub. No. WO97/10162 PCT Pub. Date Mar. 20, 1997Method for marking an object where the object is placed in a package whereby a pattern in said package is caused to make a marking in said object. Objects being marked with the above method. The invention is especially useful for marking solid or semi-solid formulations of drugs, candy and food-stuff. Specifically the invention is useful to mark nicotine-containing chewing gums. Other solid or semi-solid objects can equally well be marked using the present invention.
Patent DE-69621254-D1 (DE)
Inventor: BERGKVIST ROLF
IPC: A23L7/104
Filed: 1996-10-07
Granted: 2002-06-20
Abstract: PCT No. PCT/SE96/01266 Sec. 371 Date Apr. 6, 1998 Sec. 102(e) Date Apr. 6, 1998 PCT Filed Oct. 7, 1996 PCT Pub. No. WO97/12525 PCT Pub. Date Apr. 10, 1997A process for the preparation of nutritionally valuable products from cereals by means of an enzymatic degradation of the starch present in the cereals is provided. Gelatinization and degradation of the starch to soluble dextrines and their continued degradation to more simple oligosaccharides is carried out in a single step. Additionally, a plant for carrying out the process is provided.
Patent DE-69625167-D1 (DE)
Inventor: HARRISON ROBERT G
IPC: H04N5/445
Filed: 1996-07-18
Granted: 2003-01-16
Abstract: Systems (34) which have an integrated unit that allows both television signals and information retrieved from an onboard information storage device (32) to be presented in a visual, audio or video/audio learn-while-doing form via output devices such as television screens and audio speakers. The operating mode - television or stored information retrieval and display - is selected by the user. The user is coached through steps leading to retrieval and presentation of the wanted information if the information retrieval mode is selected. To this end, the data storage devices are encoded with data corresponding to: (a) information for coaching a user in accomplishing one or more steps of a specified task in learn-then-perform way, and (b) an instruction set which enables the user access to access the information on a user-selected step of the task. Methods for providing the encoded data storage devices and for employing those devices in the operation of the systems are also described. A novel remote control (36) allows the system user to choose the mode of operation and to navigate the steps needed to reach the wanted information from a location convenient to the user.
Patent DE-69628153-D1 (DE)
Inventor: TAYLOR LESLI A
IPC: A61K33/14
Filed: 1996-03-12
Granted: 2003-06-18
Abstract: A method for the topical treatment of skin affected with acne, rosacea, or a combination thereof. Sodium chloride in a substantially pure form is topically applied to the affected skin by gently gliding the sodium chloride over the affected skin in a manner insufficient to cause abrasion and debridement of the affected skin. A solid block of about 98% to about 100% by weight sodium chloride free of a carrier and/or free of other topical acne-treatment medicaments and/or free of other topical rosacea-treatment medicaments should be used. The applied sodium chloride is left on the skin. Preferably, the affected skin is pre-moistened with water from shaving, bathing, splashing water on the skin, and the like prior to gliding the sodium chloride thereon.
Patent DE-69710757-D1 (DE)
Inventor: PAILLARD BRUNO
IPC: A61K31/165
Filed: 1997-08-26
Granted: 2002-04-04
Abstract: The invention concerns a pharmaceutical composition with prolonged release, for oral administration of a single daily dose of 60 to 140 mg of Milnacipran, having a multi-particulate form containing a plurality of microgranules each comprising an active microsphere containing a saccharose and/or starch nucleus of a size between 200 and 2000 mum and containing 150 to 1000 mum of Milnacipran and a binding agent, each microgranule being coated with a film having a base of at least one polymer insoluble in water but permeable to physiological liquids, of a thickness between 20 and 100 mum, the said pharmaceutical composition enabling an in vitro release corresponding to the following pattern: between 10 and 55% of the dose released in 2 hours, between 40 and 75% of the dose released in 4 hours, between 70 and 90% of the dose released in 8 hours, between 80 and 100% of the dose released in 12 hours.
Patent DE-69715817-D1 (DE)
Inventor: CARTER KEVIN
IPC: A61F2/44
Filed: 1997-01-16
Granted: 2002-10-31
Abstract: PCT No. PCT/US97/00630 Sec. 371 Date Jul. 16, 1998 Sec. 102(e) Date Jul. 16, 1998 PCT Filed Jan. 16, 1997 PCT Pub. No. WO97/25945 PCT Pub. Date Jul. 24, 1997A dowel (300) is provided by obtaining a plug from the shaft (diaphysis) of various long bones. The dowel (300) has an intra-medullary canal (30) which can be packed with any of a variety of osteogenic materials. The dowel (300) has a cortical surface (10) into which an instrument attachment hole (15) may be machined and onto which an alignment mark (16) may be inscribed for proper orientation of the intra-medullary canal (30) or a driver slot (56) which may be used to assist in further machining of the bone dowel (300). The dowel (300) ha a chamfered insertion end and has improved biomechanical and vertebral fusion induction properties as compared to standard dowels known in the art. A threaded (31) or grooved (32) dowel (300) and an apparatus (400) for efficient production thereof are also provided.
Patent DE-69716259-D1 (DE)
Inventor: ZACHARY E
IPC: F02C7/30
Filed: 1997-05-02
Granted: 2002-11-14
Abstract: The net output of an industrial gas turbine (101) including an axial-flow multistage compressor (103) having an inlet (102) for acquiring a working fluid comprising air, is augmented using a process comprising the step of providing, to the working fluid acquired by the axial-flow compressor (103), droplets of a liquid which possesses a high latent of vaporization to reduce the temperature increase of the working fluid caused by compression and to thereby achieve an increase in the net output of the gas turbine (101) as measured against the net output of the gas turbine (101) under comparable conditions but without said liquid being provided. The droplets are provided by droplet-addition means (201) located a sufficient distance away from the compressor inlet (102) whereby, in the event of any element of said means breaks away and is carried with the inlet air towards the compressor inlet, that element is gravitationally pulled to a lower surface (136) of an inlet duct (133) to the compressor inlet (102) before the air reaches said inlet (102).
Patent DE-69717490-D1 (DE)
Inventor: ASPE DANIEL
IPC: G01N33/533
Filed: 1997-12-12
Granted: 2003-01-09
Abstract: The invention concerns a method for obtaining a fluorescent conjugate between a carrier molecule having at least an amino, hydroxy, carboxy and/or sulphydryl group and a fluorophore reagent having at least a functional group capable of reacting with said amino, hydroxy, carboxy and/or sulphydryl group(s), which consists in bringing said molecule and said fluorophore reagent in the presence of an aqueous solution of a water-soluble macrocycle. The invention also concerns the conjugates obtained by this method and their use.
Patent DE-69717815-D1 (DE)
Inventor: HOWARD NORMAN
IPC: A23C/
Filed: 1997-05-30
Granted: 2003-01-23
Abstract: Disclosed is an acidic composition for human consumption, comprising creatine. In particular the composition is conveniently an isotonic drink for storage at 4 DEG  C., or is a dry stable powder which may be stored at ambient temperature.
Patent DE-69718390-D1 (DE)
Inventor: MASHIMA HIROSHI
IPC: B01D19/04
Filed: 1997-02-27
Granted: 2003-02-20
Abstract: In a water recycle painting system wherein a water paint is spray painted on an object to be painted in a painting booth, and wherein over sprayed paint captured in booth circulating water is condensed and recovered to be mixed with the water paint for reuse, a method for suppressing foams in booth circulating water for effectively suppressing foams in booth circulating water generated when spray painting water paint to thereby maintain a good working environment, the method being characterized in that the booth circulating water includes a silicone antifoamer (A) and a hydrophilic high-boiler (B).   <IMAGE>
Patent DE-69720811-D1 (DE)
Inventor: RAMASAMY KANDASAMY
IPC: C07H19/044
Filed: 1997-10-15
Granted: 2003-05-15
Abstract: Novel monocyclic L-Nucleoside compounds have the general formula  Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in terms of mechanism, embodiments of the novel compounds show immunomodulatory activity, and are expected to be useful in modulating the cytokine pattern, including modulation of Th1 and Th2 response.
Patent DE-69725020-D1 (DE)
Inventor: MERINGDAL FRODE
IPC: G01L9/04
Filed: 1997-02-20
Granted: 2003-10-23
Abstract: PCT No. PCT/NO97/00053 Sec. 371 Date Aug. 26, 1998 Sec. 102(e) Date Aug. 26, 1998 PCT Filed Feb. 20, 1997 PCT Pub. No. WO97/32190 PCT Pub. Date Sep. 4, 1997A pressure sensor for measuring high pressures, the sensor being adapted to act externally on a measuring element, the measuring element having a central cavity and being composed of two parts which are sealingly joined in order to form the cavity, and comprising sensor means for measuring the mechanical stress condition of the measuring element. The two parts of the measuring element are manufactured in planar technology form silicium or quartz and have a substantially larger length than lateral dimensions, the cavity being oriented in a longitudinal direction, and the sensor means being piezo-resistive elements lying adjacent to the external or internal surface of the measuring element.
Patent DE-69733433-D1 (DE)
Inventor: SADOWSKI L
IPC: A61M5/30
Filed: 1997-03-28
Granted: 2005-07-07
Abstract: An injector nozzle which has a body defining a chamber. A portion of the body has an orifice which communicates with the chamber for allowing fluid to enter into or exit from the chamber. The nozzle body includes at least one depression which is configured and dimensioned to cooperatively engage a tab member of an associated component for coupling thereto. The depression is also configured and dimensioned to positively lock the body to the associated component. The body portion which contains the depression is spaced proximally from the orifice. Also, an adapter for coupling the nozzle to a fluid container. The adapter includes a tubular member having first and second ends and a wall therebetween. The wall includes a passageway therethrough with the first end being dimensioned and configured to cooperatively engage the nozzle. The orifice of the nozzle generally aligns with the wall passageway for fluid communication therebetween. The second end of the adapter is configured and dimensioned to cooperatively engage a fluid container. These devices can be used in combination to provide a system for filling an injector with medicament.
Patent DE-69736550-D1 (DE)
Inventor: OCALI OGAN
IPC: G01R33/54
Filed: 1997-04-18
Granted: 2006-10-05
Abstract: The invention provides a method for magnetic resonance imaging and spectroscopic analysis of a specimen which includes positioning the specimen within a main magnetic field and introducing an antenna having a loopless antenna portion in close proximity to the specimen. Radio frequency pulses are provided to the region of interest to excite magnetic resonance signals, gradient magnetic pulses are applied to the region of interest with the antenna receiving magnetic resonance signals and emitting responsive output signals. A processor processes the responsive output signals to provide image information for display in a desired manner. The method in a preferred form involves employing a flexible antenna. The method in another preferred form involves employing an impedance matching circuit electrically interposed between the loopless antenna and the processor to enhance radio frequency power transfer and magnetic resonance signal-to-noise ratio from the loopless antenna to the processor. The method may be used on a wide variety of specimens and in a preferred use is introduced into small blood vessels of a patient to facilitate determination of atherosclerotic plaque. Medical intervention procedures, such as plaque removal, may be employed generally simultaneously with the imaging of the present invention. Corresponding apparatus and magnetic resonance antenna assembly are provided.
Patent DE-69739325-D1 (DE)
Inventor: BLUBAUGH ELMO A
IPC: G01N27/333
Filed: 1997-12-17
Granted: 2009-05-07
Abstract: A sensor that is capable of accurately measuring glucose and other analytes in low oxygen environments is provided. The sensor employs an enzyme-containing membrane comprising a semi-interpenetrating polymer network which is infiltrated by an enzyme. The enzyme-containing membrane increases oxygen transport to the enzyme such that oxygen is not a limiting factor in the oxidation taking place at the enzyme.
Patent DE-69803580-D1 (DE)
Inventor: STOCCHI GABRIELE
IPC: B67C3/26
Filed: 1998-05-26
Granted: 2002-03-14
Abstract: A process for filling containers simultaneously with their sterilization, including also the evacuation of the aeriform content of the containers that is exhausted directly to the outside without flowing back in the general tank containing the filling process fluids.
Patent DE-69808025-D1 (DE)
Inventor: SHIMIZU TAKAYOSHI
IPC: F02B77/08
Filed: 1998-12-07
Granted: 2002-10-24
Abstract: A corrosion resistant sintered body having excellent ductility is provided by sintering, at a temperature of not less than about 1050°C to less than about 1300°C, powders which are composed by adding a metal compound of B to and mixing with powders of ferrite stainless steel containing: C ≤ 0.1 wt%, Si ≤ 3.0 wt%, Mn ≤ 0.30 wt%, Ni ≤ 2.0 wt%, 11 wt% ≤ Cr ≤ 22 wt%, Mo ≤ 3.0 wt%, the rest being substantially Fe. The amount of B in the mixed powders is between more than about 0.03 wt% and less than about 0.2 wt% based on the weight of the powder.
Patent DE-69812091-D1 (DE)
Inventor: TROMBETTA ANTONIO
IPC: A61F13/15
Filed: 1998-05-29
Granted: 2003-04-17
Abstract: The present invention provides an absorbent composite web comprising a primary material having a top surface, a bottom surface, and a plurality of apertures extending from the top surface to the bottom surface. Furthermore, a secondary material is positioned adjacent to the primary material bottom surface. The secondary material extends into the plurality of apertures in the primary material.
Patent DE-69814145-D1 (DE)
Inventor: FABIAN MASSIMILIANO
IPC: A23F5/16
Filed: 1998-10-24
Granted: 2003-06-05
Abstract: Green coffee is introduced into a container where it is subjected to continuous mixing in temperature continuous mixing in temperature ranging between environment and values close to 120° C. and water vapor is introduced into said container until the single beans of coffee have become porous and permeable; micotoxins are removed by extraction with a solvent in an acid environment obtained with a given acid or with a buffer solution with a given acid pH.
Patent DE-69815724-D1 (DE)
Inventor: TANAKA HIDEKAZU
IPC: A61K8/00
Filed: 1998-12-22
Granted: 2003-07-24
Abstract: Directed to a transparent skin care compostion comprising: (a) two or more surfactants selected from the group consisting of polyoxyethylene sorbit tetraalkyl ester, polyoxyethylene castor oil ester and/or polyoxyethylene hydrogenated castor oil ester, polyoxyethylene alkyl phosphate or salts, and mixtures thereof; (b) an oil compound, (c) a polyhydric alcohol, and (d) water. The oil compound in the composition is substantially solubilized in the transparent skin care composition.
Patent DE-69839614-D1 (DE)
Inventor: HOTANI SETSUO
IPC: B24D13/08
Filed: 1998-09-30
Granted: 2008-07-24
Abstract: Disclosed are a brush roll and brush elements thereof which are useful for grinding, polishing cleaning or otherwise treating steel sheets, plates or strips. The brush roll and the brush element have in common the following feature. A brush element U comprises an assembly of annular disks 2 joined together as arranged side by side in the direction of width thereof and each having polishing bristles or cleaning yarns 1 implanted in an outer periphery thereof to provide an assembly of such brush elements U as fitted around a shaft 3 and arranged side by side longitudinally of the shaft 3, the brush element U being engageable with the shaft 3 by keyways 5 formed in both a peripheral surface of the shaft 3 and an inner peripheral surface of the brush element U and equidistantly spaced apart circumferentially of the peripheral surfaces and by sunk keys 4 fitting in the respective keyways 5, the sunk keys 4 and the keyways 5 being each so profiled in cross section that the sunk key 4 is prevented from slipping out of the keyway 5a in the brush element U radially of the brush element U, the sunk keys 4 having a length not larger than the length of the brush element U, each of the sunk keys 4 being expandable or contractable widthwise thereof and tightly engageable in the keyway 5 when expanded and disengageable therefrom when contracted, the sunk key 4 being prevented from slipping out of the keyway 5 in the brush element U longitudinally of the keyway by retaining means C when fitted as contracted in the keyway 5. <IMAGE>
Patent DE-69901809-D1 (DE)
Inventor: VAN VUGT ADRIAAN
IPC: G01C21/00
Filed: 1999-03-13
Granted: 2002-07-18
Abstract: The navigation system according to the invention includes a receiver for the reception of a traffic message about one of the road segments in the database of the system. The traffic message includes an event and a location indicating the directly affected road segment. After reception, the system defines a number of road segments as being additionally affected by the traffic event. Subsequently when using road segments from the database, the system treats the directly affected road segment and the additionally affected road segments as being affected by the traffic event, thus taking into account an area of influence around the traffic event.
Patent DE-69904263-D1 (DE)
Inventor: BONAITI MARCO
IPC: F16B45/02
Filed: 1999-07-05
Granted: 2003-01-16
Abstract: A connector with snap closure comprises a pair of levers (3, 3') elastically stressed, each lever (3, 3') having a formed end (8, 8') for performing the closure for the connector (1), and the other formed end (9, 9'; 10, 10') for providing a snap element and an element for manual control of opening of the connector (1). <IMAGE>
Patent DE-69904743-D1 (DE)
Inventor: DRURY PAUL RAYMOND
IPC: B41J2/175
Filed: 1999-10-22
Granted: 2003-02-06
Abstract: Droplet deposition apparatus comprises a fluid chamber comprising an actuator actuable by electrical signals to effect ejection of droplets from the fluid chamber, a drive circuit for supplying the electrical signals; and a conduit for supplying droplet fluid to said fluid chamber, the drive circuit being in substantial thermal contact with the conduit so as to transfer a substantial part of the heat generated in the drive circuit to the droplet fluid.