baber/WOPTO huggingface dataset:
Patent AU-2019297391-A1 (AU)
Title: Oligonucleotides for modulating Tau expression
Inventor: HAGEDORN PETER
IPC: C12N15/113
Filed: 2019-07-03
Abstract: The present invention relates to antisense oligonucleotides that are capable of modulating expression of Tau in a target cell. The oligonucleotides hybridize to MAPT mRNA. The present invention further relates to conjugates of the oligonucleotide and pharmaceutical compositions and methods for treatment of Tauopathies, Alzheimzer's disease, fronto-temporal dementia (FTD), FTDP-17, progressive supranuclear palsy (PSP), chronic traumatic encephalopathy (CTE), corticobasal ganglionic degeneration (CBD), epilepsy, Dravet syndrome, depression, seizure disorders and movement disorders.
Patent AU-2019318543-A1 (AU)
Title: Transglutaminase 2 (TG2) inhibitors
Inventor: CAMPBELL DAVID
IPC: A61K38/05
Filed: 2019-08-09
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit transglutaminase 2 (TG2). Also described herein are methods for using such TG2 inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from TG2 inhibition.
Patent AU-2019323942-A1 (AU)
Title: Devices and methods for ablating biological tissue
Inventor: MORRIS DAVID
IPC: A61B18/00
Filed: 2019-08-20
Abstract: Disclosed herein is a tissue ablation device comprising a sheath and a probe. The sheath is positionable within body tissue and comprises a distal end, a proximal end and a lumen extending therebetween. The probe comprises an elongate portion configured to be slidably received in the lumen, the elongate portion housing an electrode that is deployable from a distal end of the probe's elongate portion into a substantially planar deployed configuration when the distal end of the elongate portion is located at or beyond the distal end of the sheath. An angle of deployment of the electrode from the distal end of the probe (and hence into the body tissue, in use) is selectable by orientating the probe with respect to the sheath.
Patent AU-2019382828-A1 (AU)
Title: Novel applications of hop acids
Inventor: BEDDIE DAVID
IPC: C12C7/28
Filed: 2019-11-19
Abstract: The present invention relates to novel applications of hop acids and formulations using hop acids. More specifically, the present invention relates to formulations comprising hop acids to stabilise or emulsify hop oils or other essential oils in aqueous media. We describe an aqueous emulsifiable composition comprising 0.01-5.00 wt% of at least one essential oil and 0.005-10.0 wt% of at least one hop acid, the balance being water. We also describe a method of stabilising or emulsifying an essential oil or mixture of essential oils. The method comprises mixing the essential oil or mixture of essential oils with at least one hop acid to form an essential oil and hop acid mixture and mixing the essential oil and hop acid mixture with water. We further describe the use, as an emulsifier, of a composition comprising at least one hop acid and beverages obtainable with the composition.
Patent AU-2019398202-A1 (AU)
Title: Multigene construct for immune-modulatory protein expression and methods of use
Inventor: CANTON DAVID A
IPC: A61K48/00
Filed: 2019-12-11
Abstract: Provided are expression vector constructs encoding IL-12 p35 and IL-12 p40 proteins where each protein or component thereof can be expressed utilizing appropriate promoters and/or translation modifiers. Also provided are methods of use for the expression vectors.
Patent AU-2019399137-A1 (AU)
Title: A receiving enclosure
Inventor: PEADY SETH
IPC: A47G29/14
Filed: 2019-12-12
Abstract: A receiving enclosure for receiving goods, the receiving enclosure having one or more doors movable between an open position and a closed position, and a locking device adapted to releasably secure the one or more doors in the closed position.
Patent AU-2020200968-A1 (AU)
Title: Method and cut guide for biplanar wedge osteotomy
Inventor: AWTREY MATTHEW GEORGE
IPC: A61B17/15
Filed: 2020-02-11
Abstract: A wedge osteotomy method inserts a first wire into a first bone of the foot, distal from tissue to be removed. A second wire is inserted into a second bone, so the tissue to be removed is distal from the second wire. A cut guide is pivoted about the first wire, until a first axis of the cut guide is parallel with a longitudinal axis of the first metatarsal. The cut guide has a slot 0 perpendicular to the first axis for guiding a cutter to cut bone, while the first axis is aligned with the longitudinal axis of the first metatarsal. The cut guide is then pivoted about the second wire, until the first axis is aligned with the longitudinal axis of the talus, and bone is cut through the slot, to form a second planar cut into or through bone material.
Patent AU-2020201502-A1 (AU)
Title: Stabilizer compositions and methods for using same for protecting organic materials from UV light and thermal degradation
Inventor: ENG J MON HEI
IPC: C08K5/3475
Filed: 2020-02-28
Abstract: Stabilizer compositions having a stabilizing amount of at least one co-active agent; and a stabilizing amount of any one or more ultraviolet light absorber chosen from an ortho hydroxyphenyl triazine, an ortho-hydroxy benzophenone, or an ortho-hydroxyphenyl benzotriazole, optionally in combination with a stabilizing amount of a hindered amine light stabilizer, are provided herein, along with masterbatch concentrates containing same, and processes for using same for stabilizing organic materials to protect against light and thermal degradation due to exposure to UV irradiation.
Patent AU-2020202961-A1 (AU)
Title: Negative pressure wound closure device
Inventor: DUNN RAYMOND M
IPC: A61B17/03
Filed: 2020-05-04
Abstract: NEGATIVE PRESSURE WOUND CLOSURE DEVICE The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Preferred embodiments can utilize tissue grasping elements to apply a wound closing force to the tissue. ]
Patent AU-2020204812-A1 (AU)
Title: Pallet module, assortment of pallet modules, and pallet assembly built of the same
Inventor: REALI MATTHEW
IPC: B65D19/24
Filed: 2020-01-06
Abstract: Pallet module (10) configured to allow formation of a nested pallet assembly of at least two similar pallet modules, the pallet module comprising a main structural body (100) exhibiting a generally quadrilateral peripheral border (100A) with first to fourth lateral sides (101-104), first and second lateral flanges (110, 120) extending outwardly from the peripheral border along the first and second lateral sides (101, 102), the first and second lateral flanges being configured to cooperate with first and second lateral grooves (130, 140) extending inwardly from the peripheral border along the third and fourth lateral sides (103, 104) of another similar pallet module to form the nested pallet assembly, a foot structure (90) disposed on a lower side (100C) of the main structural body, and first and second toggle latch components (51,52) arranged in the vicinity of the first and second lateral sides, respectively, configured to cooperate and releasably interlock with third and fourth toggle latch components (53, 54) arranged in the vicinity of the third and fourth lateral sides, respectively, of another similar pallet module of the nested pallet assembly.
Patent AU-2020209539-A1 (AU)
Title: Needleless access connector facilitating instrument delivery to a catheter assembly
Inventor: BURKHOLZ JONATHAN KARL
IPC: A61M39/10
Filed: 2020-01-10
Abstract: A needleless access connector may include a body, which may include a proximal end configured to couple to an instrument delivery device and a distal end configured to couple to a peripheral intravenous catheter assembly. The needleless access connector may also include an accordion valve disposed within the body between the proximal end and the distal end. The accordion valve may include an accordion portion. In response to compression of the accordion portion and opening of the accordion valve, a straight pathway extending through the proximal end and the distal end may be exposed such that an instrument of the instrument delivery device may move distally from the proximal end to the distal end through the straight pathway without bending.
Patent AU-2020215673-A1 (AU)
Title: Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors
Inventor: HUANG TAISHENG
IPC: C07D471/04
Filed: 2020-01-28
Abstract: This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which modulate the activity of adenosine receptors, such as subtypes A2A and A2B receptors, and are useful in the treatment of diseases related to the activity of adenosine receptors including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.
Patent AU-2020223747-A1 (AU)
Title: Bell mouth, air supply assembly including the bell mouth, and air supply control system using the bell mouth
Inventor: PARK JUN KYU
IPC: F23L1/00
Filed: 2020-08-28
Abstract: A bell mouth includes an upstream body including an 
upstream-side opening formed to allow air introduced from an air 
supply duct to pass through and an upstream measurement portion 
5 connected with a differential-pressure acquisition device that 
uses pressure of the air in the upstream-side opening, in which 
the air supply duct guides the air into a water-heating device 
from the outside, a differential-pressure generation part that 
is located downstream of the upstream body with respect to a flow 
10 direction of the air and that has a structure that reduces the 
pressure of the air passing through the differential-pressure 
generation part, and a downstream body including a downstream
side opening formed to allow the air passing through the 
differential-pressure generation part to pass through and a 
15 downstream measurement portion connected with the differential
pressure acquisition device that obtains a difference between the 
pressure of the air passing through the downstream-side opening 
and facing toward a blower of the water-heating device and the 
pressure of the air in the upstream-side opening.
3/12 
21 
33 
12 Upper 
32 Lower 
31 10 D1 
30 
FIG.3
Patent AU-2020232853-A1 (AU)
Title: Self-neutralizing amino acid based cationic compositions
Inventor: BURGO ROCCO V
IPC: A61K31/198
Filed: 2020-03-09
Abstract: The invention described herein includes a self-neutralizing amino acid-based cationic composition that contains an amino acid-based cationic ester, a nonionic amphiphile, and an anhydrous buffering agent. In an embodiment, the composition, when dispersed or dissolved in an aqueous solvent, provides a resultant solution/dispersion having a pH of greater than about 4. The amino acid-based cationic ester may be a reaction product of (i) an amino acid having a non-polar side chain, and an amine group that has been neutralized with an acid; with (ii) a long chain fatty alcohol. Also included within the scope of the invention are methods of preparing a self-neutralizing amino acid-based cationic composition, such method including combining an amino acid-based cationic ester, a nonionic amphiphile and an anhydrous buffering agent. The resulting composition is in an anhydrous solid form. Formulations containing the amino acid-based cationic ester and/or a composition that includes it, are also disclosed.
Patent AU-2020259405-A1 (AU)
Title: Methods of treating renal cancer with an anti- PSMA/CD3 antibody
Inventor: MCDEVITT THERESA
IPC: C07K16/28
Filed: 2020-04-17
Abstract: Bispecific monoclonal antibodies and methods for treating cancer are set forth herein.
Patent AU-2020260398-A1 (AU)
Title: Common light chain mouse
Inventor: MCWHIRTER JOHN
IPC: C12N15/85
Filed: 2020-10-27
Abstract: A genetically modified mouse is provided, wherein the mouse is incapable of rearranging 
and expressing an endogenous mouse immunoglobulin light chain variable sequence, wherein 
the mouse expresses only one or two human light chain variable domains encoded by human 
immunoglobulin sequences operably linked to the mouse kappa (K) constant gene at the 
endogenous mouse K locus, wherein the mouse expresses a reverse chimeric antibody having 
a light chain variable domain derived from one of only two human light chain variable region 
gene segments and a mouse K constant domain, and a human heavy chain variable domain 
and a mouse heavy chain constant domain, from an endogenous mouse heavy chain locus.  
Bispecific epitope-binding proteins that are fully human are provided, comprising two different 
heavy chains that associate with an identical light chain that comprises a variable domain 
derived from one of two different human light chain variable region gene segments.
Patent AU-2020270498-A1 (AU)
Title: System, method, and interfaces for work product management
Inventor: JARVIS JAMES JOHN
IPC: G06Q10/10
Filed: 2020-11-18
Abstract: A method includes receiving an initial electronic file where the initial electronic file is 
associated with a work product. The method further includes resolving, automatically, 
an electronic file content type associated with the initial electronic file and executing, 
automatically, at least one subscription program associated with the electronic file 
content type of the initial electronic file. The method further includes retrieving an 
enhanced electronic file based on a matter security level. The enhanced electronic file 
is associated with an indication of completion of the at least one subscription 
program. Another embodiment includes extracting a set of metadata from the initial 
electronic file and storing the set of metadata from the initial electronic file in a 
memory. Yet another embodiment includes populating, automatically, at least one 
field within a field-oriented electronic file from the set of metadata.
Patent AU-2020284406-A1 (AU)
Title: Composition for the protection and repair of the blood brain barrier
Inventor: BARRITAULT DENIS
IPC: A61K31/721
Filed: 2020-04-30
Abstract: The present invention relates to a pharmaceutical composition for its application as a medicament, in particular for use in the protection of the blood brain barrier and/or the repair and/or the restoration of the blood brain barrier. The present invention finds an application in particular in the therapeutic, pharmaceutical and veterinary fields.
Patent AU-2020294284-A1 (AU)
Title: Hand-held surface cleaning device
Inventor: TONDERYS DANIEL
IPC: A47L5/24
Filed: 2020-12-23
Abstract: A hand-held surface cleaning device comprising a handle portion at a first end of the device 
configured to receive at least one battery; a nozzle at a second end of the device defining a nozzle 
dirty air inlet; a motor section adjacent the handle portion comprising a motor configured to be 
powered by the at least one battery for generating suction and drawing air into the nozzle dirty 
air inlet; a removable dust cup adjacent the motor section comprising a collection area and a door, 
the dust cup being coupled to the nozzle and in fluid communication with the nozzle dirty air 
inlet for receiving debris through the nozzle dirty air inlet and storing the debris in the collection 
area, the door being disposed at a first end of the dust cup and having a closed position for 
retaining the debris in the collection area and an open position for emptying the debris from the 
collection area, the device having a substantially continuous width from the motor section to the 
second end of the device; and a filter configured to be disposed in the dust cup, the filter being 
removable from an opening at a second end of the dust cup when the dust cup is removed from 
the device.
Patent AU-2020325014-A1 (AU)
Title: Compositions and methods for chromosome rearrangement
Inventor: ARMSTRONG CHARLES LESTER
IPC: C12N15/63
Filed: 2020-08-04
Abstract: Methods and compositions for evaluating the efficiency of chromosomal rearrangement are provided. In some examples, systems comprising a first DNA molecule comprising the N- terminal portion of a first split reporter coding sequence linked to the C-terminal portion of a second split reporter coding sequence via a first intron, and a second DNA molecule comprising the N-terminal portion of said second split reporter coding sequence linked to the C-terminal portion of said first split reporter coding sequence via a second intron. The introns comprise at least one target site recognized by a genome editing reagent, such as a recombinase or endonuclease, such that recombination results in expression of the first or second reporter coding sequence following splicing of the introns.
Patent AU-2020325957-A1 (AU)
Title: Fluorine-containing polymer for metal-clad laminated sheet, composition for metal-clad laminated sheet, curable composition, metal-clad laminated sheet and printed substrate
Inventor: ISHIKAWA TAKUJI
IPC: B32B15/082
Filed: 2020-08-06
Abstract: To provide a fluorine-containing polymer for a metal-clad laminated sheet that is highly compatible with an epoxy resin. A fluorine-containing polymer for a metal-clad laminated sheet, said fluorine-containing polymer comprising a polymerization unit derived from a fluorine-containing vinyl monomer and a polymerization unit derived from a vinyl ester monomer (excluding the aforesaid fluorine-containing vinyl monomer), characterized in that the ratio of the total amount of a polymerization unit derived from a hydroxyl group-containing monomer and a polymerization unit derived from a carboxyl group-containing monomer is 1 mol% or less relative to the whole polymerization units.
Patent AU-2020346818-A1 (AU)
Title: An immunotherapeutic for prostate cancer treatment
Inventor: MILLER KEITH DOUGLAS
IPC: C12N15/62
Filed: 2020-09-10
Abstract: The present disclosure describes a GnRH therapeutic for neutralizing GnRH levels in subjects which can reduce testosterone levels to attenuate or eliminate prostate cancer cell growth and/or metastasis. The therapeutic is produced synthetically. The GnRH therapeutic includes a hapten carrier (hC) comprising a monomeric peptide (MP), synthesized separately from the GnRH peptide, and following self-assembly of the hC, GnRH is covalently coupled to form a GnRH-hC conjugate which can serve as a therapeutic. The MP includes heptad repeats following a specific pattern. The hC can include a GnRH peptide attached to a monomeric peptide prior to self-assembly to form a therapeutic. Optionally, the GnRH-hC conjugate further includes one or more T-cell epitopes at the N- and/or C-terminus of the one or more amphipathic alpha-helices. The present disclosure also describes compositions including immunogenic compositions including the therapeutics described herein.
Patent AU-2020349600-A1 (AU)
Title: Detection of nutrient deficiency in plants
Inventor: TOPOROV ALEXANDER
IPC: G06T7/90
Filed: 2020-09-17
Abstract: A casing (6) for use in a system for estimating a deficiency of a nutrient in a leaf (100) from a plant, and a system and method using such a casing (6). The casing (6) comprises an upper cover (8) adapted to receive an imaging device including a camera (3) and a light source, wherein the upper cover (8) comprises at least one opening (9) to allow the camera (3) and light source to access an interior of the casing (6), a bottom plate (12) having a surface (13) facing the interior of the casing (6), which surface (13) is provided with a pattern including areas having a predefined color, and a side wall (7), wherein, in use, a leaf (100) is placed on the surface (13) and an image (200) is acquired of the leaf (100), whereby the areas allow color calibration of an acquired image.
Patent AU-2020358142-A1 (AU)
Title: Key generation for use in secured communication
Inventor: LO HOI-KWONG
IPC: H04L9/30
Filed: 2020-09-30
Abstract: Systems and methods for key generation for secure communication between a first user computing device and a second user computing device without requiring direct communication during key generation. The method using a plurality of privacy providers and a first private table and a second private table. The method including: performing by the second user computing device: receiving indexes each associated with a value in the second private table, each index received from the respective privacy provider sharing those values, each index associated with a value that matches an indexed value in the first private table received by the respective privacy provider from the first user computing device; and generating a common key for the secure communication by combining the indexed values of the second private table.
Patent AU-2020362426-A1 (AU)
Title: Automatic landing system for vertical takeoff/landing aircraft, vertical takeoff/landing aircraft, and control method for landing of vertical takeoff/landing aircraft
Inventor: KOJIMA TORU
IPC: B64C29/00
Filed: 2020-09-01
Abstract: The purpose of the present invention is to accurately land a vertical takeoff/landing aircraft on a target landing point. This automatic landing system is provided with: an imaging device mounted on a vertical takeoff/landing aircraft; a relative-position acquiring unit that performs image processing on an image, of a marker provided to a landing target point, captured by the imaging device, and that acquires a relative position between the vertical takeoff/landing aircraft and the landing target point; a relative-altitude acquiring unit for acquiring a relative altitude between the vertical takeoff/landing aircraft and the landing target point; and a control unit for controlling the vertical takeoff/landing aircraft in a plurality of control modes so that the relative position becomes zero, wherein the control modes include a hovering mode and a landing mode. In the hovering mode, the relative altitude of the vertical takeoff/landing aircraft is lowered to a predetermined relative altitude when the relative position is within a first threshold value. The transition to the landing mode takes place upon satisfaction of predetermined conditions including a condition in which the relative position is within a predetermined threshold value which is less than the first threshold value. In the landing mode, the relative altitude of the vertical takeoff/landing aircraft is further lowered so as to make a landing on the landing target point.
Patent AU-2020368656-A1 (AU)
Title: Vaccine product
Inventor: LABOVITIADI OLGA
IPC: A61K9/00
Filed: 2020-10-16
Abstract: The present invention provides a vaccine product comprising a container, wherein the container comprises an internal surface, the internal surface comprising either (i) silicon dioxide, (ii) a polymeric material, or (iii) a surface treated with ethylene oxide; and a vaccine composition within the container in contact with the internal surface, wherein the vaccine composition comprises virus particles.
Patent AU-2020386104-A1 (AU)
Title: Digging apparatus with safety mechanism
Inventor: CHUNG KOON FOR
IPC: B23B45/02
Filed: 2020-10-15
Abstract: Provided herein is an electric powered digging apparatus comprising: a powerhead, the power head comprises a motor and a gearbox; a handle frame, the powerhead is mounted onto the handle frame; and a drill bit, the drill bit is driven by the motor to rotate around a longitudinal axis, the electric power digging apparatus further comprises: a first safety mechanism, wherein the first safety mechanism reduces torque output to the drill bit when the powerhead spins around the longitudinal axis for an angle larger than a first threshold, and a second safety mechanism, wherein the second safety mechanism reduces torque output to the drill bit when the powerhead spins around the longitudinal drive axis at an angular speed larger than a second threshold