baber/WOPTO huggingface dataset:
Patent AU-2016205284-A1 (AU)
Title: Microfluidic cell culture of patient-derived tumor cell spheroids
Inventor: BARBIE DAVID
IPC: C12M3/00
Filed: 2016-01-07
Abstract: Provided herein are methods for culturing patient-derived tumor cell spheroids in a three-dimensional microfluidic device. The method comprises mincing primary tumor sample in a medium supplemented with serum; treating the minced primary tumor sample with a composition comprising an enzyme; collecting tumor spheroids having a diameter of 10 μηι to 500 μιη from the enzyme treated sample; suspending the tumor spheroids in biocompatible gel; and culturing the tumor spheroids in a three dimensional microfluidic device. Methods for identifying an agent for treating cancer and microfluidic devices that allow for the simultaneous exposure of the cultured patient-derived primary tumor cell spheroids to a treatment of choice and to control treatment are also provided.
Patent AU-2016210607-A1 (AU)
Title: Optimization of microgrid energy use and distribution
Inventor: OZOG MICHAEL T
IPC: G06Q50/00
Filed: 2016-08-01
Abstract: An energy distribution may include a server and one or more databases. The system may communicate with an energy provider to receive energy provider data, at least one information collector to receive information collector data such as individualized energy usage data, customer preferences, and customer or location characteristics, and the one or more databases for receiving data for optimization. The system may calculate a cost of service or avoided cost using at least one of the individualized energy usage data and a system generation cost at a nearest bus. The system may also forecast individualized demand by end-use, individualized demand by location, energy prices, or energy costs. The system may optimize energy distribution, energy use, cost of service, or avoided cost using the forecasted individualized demand by end-use, the forecasted individualized demand by location, the forecasted energy prices, and the forecasted energy costs. WO 2010/083334 PCT/US2010/021074 Buildings with Home Area Network Buildings with Whole House (HAN) Systems Smart Meters 143 147, HSmart Meter or Alternative f 141 Meter Vendor Server T _145 Data Data 1. Real or near-real time end-use usage data Real or near-real time 2. Customer willingness to be interrupted, bids whole facility usage data 127 3. Customer preferences 4. Customer demographics 5. Desired Bill Level 101 Real or near-real Grid time Locational Fourth Party Vendors Marginal Price (LMP) 49 Communication 137 135 Server Real or near-real Utility Distribution system time generation 129 characteristics; Commodity Cost Characteristics Calculate real or Distributed/Renewable 121 near-real time end- Generation (139use specific Cost 153 Required system 103 of Servi e (Cal ) Real or near-real reductions, objectives time battery level 155 157 /'159 Communication Complex Event Utlt and Customer Engine Processor WeI b Pras131 104 Forecasting System13 isrbtdSoae Statistical forecast in real or near-real time. Databases Real-time and forecasted weather conditions 107 .- -- -- - - - - - - - - 1105 17 L Real or Near-Real Time Optimizations Demand Response Mi.crogrid Optimization 111 113Y 115 Optlimization Peak Demand Micro sp tch Bill Trg t Renewal iGiatieration9 Results expressed in real or near-real time data, for application number 2010204729, is current as of 2015-11-16 23:00 AEST
Patent AU-2016224833-A1 (AU)
Title: Patient incontinence and lifting pad
Inventor: SOLOMON CHARLEEN SUZANNE
IPC: A47G9/04
Filed: 2016-04-25
Abstract: A patient incontinence and lifting pad is an apparatus utilized to absorb urine excreted by a bedridden patient as well as to facilitate turning and lifting the patient. The apparatus includes a bed pad on which the patient is able to lie as well as an attached first securing strap and a second securing strap used to anchor the bed pad to a hospital bed railing or similar structure. An elongated band of the first securing strap and the second securing strap may be attached to itself in order to anchor the bed pad. An absorbent incontinence pad insert for absorbing urine is inserted within a slot on the bed pad and may be removable/replaceable. The absorbent incontinence pad insert may be held in place within the slot by a peripheral hook fastener strip.
Patent AU-2016243988-A1 (AU)
Title: Techniques for optimizing bitrates and resolutions during encoding
Inventor: AARON ANNE
IPC: H04N21/234
Filed: 2016-03-10
Abstract: In one embodiment of the present invention, an encoding bitrate ladder selector tailors bitrate ladders to the complexity of source data. Upon receiving source data, a complexity analyzer configures an encoder to repeatedly encode the source data-setting a constant quantization parameter to a different value for each encode. The complexity analyzer processes the encoding results to determine an equation that relates a visual quality metric to an encoding bitrate. The bucketing unit solves this equation to estimate a bucketing bitrate at a predetermined value of the visual quality metric. Based on the bucketing bitrate, the bucketing unit assigns the source data to a complexity bucket having an associated, predetermined bitrate ladder. Advantageously, sagaciously selecting the bitrate ladder enables encoding that optimally reflects tradeoffs between quality and resources (e.g., storage and bandwidth) across a variety of source data types instead of a single, "typical" source data type.
Patent AU-2016247219-A1 (AU)
Title: Animal model expressing luciferase under control of the myelin basic protein promoter (MBP-luci) and use of the model for bioluminescence in vivo imaging
Inventor: CAO JAMES
IPC: C12N15/85
Filed: 2016-10-21
Abstract: A Myelin Basic Protein-luciferase bioimaging noninvasive model to visualize and quantify demyelination and remyelination events in the CNS at transcriptional level in vivo is provided. Luciferase-expressing transgenic animals were generated with myelin basic protein (MBP) promoter coupled to firefly luciferase reporter. The MBP-luci bioimaging model provides a means to monitor myelination status and the efficacy of a remyelination modulating test compound. An advantage of bioimaging is that a subject in a longitudinal study can serve as its own control. The same subject can be tracked over a demyelination and remyelination process continuously over a period of at least 10 weeks. This model enables normalization of individual animal imaging response and provides quality data with considerably reduced variance. In addition, because cohorts of animals need not be sacrificed at different time points, reduction in the number necessary for a compound efficacy study is possible.
Patent AU-2016250442-A1 (AU)
Title: Process of an apparatus for notification of financial documents and the like.
Inventor: BLAIR ANDREW
IPC: G06Q40/00
Filed: 2016-10-28
Abstract: A payee (300A) sends a financia document (335) such as an invoice to a payer (JA) via a payment adviser service (2001, 3001), The payer (1A) sends a financial document (45) such as an advice of payment to the payment adviser service (2001, 3001) and instructions for payment (80) to a payment clearance system (100), The payment clearance system sends to the payee (300A) information on where to access the finandal document (45.) by including it in the payee's bank statements(1)
Patent AU-2016267400-A1 (AU)
Title: Catheter system and method of ablating a tissue
Inventor: PRATTEN PETER
IPC: A61B1/313
Filed: 2016-05-25
Abstract: A catheter system for ablating a tissue portion of a body and visualising the ablation in real time, the system comprising a means for generating an optical imaging beam, a catheter including a catheter tip assembly comprising an array of first optical fibres for carrying the optical imaging beam and an ablating means, wherein the catheter tip assembly is adapted to direct said beam onto the tissue portion and capture a reflected portion of the optical imaging beam from the tissue portion. The system further includes a first switching means for switching the optical imaging beam between a plurality of the first optical fibres in the array and a means for processing the reflected portion of the optical imaging beam to account for variations in length between the first optical fibres.
Patent AU-2016279993-A1 (AU)
Title: Robotic surgical system torque transduction sensing
Inventor: KOPP BROCK
IPC: G01R19/00
Filed: 2016-06-15
Abstract: A method of verifying torque measurements of a reaction torque transducer of an instrument drive unit includes a controller receiving a verification signal, generating an acceptable range of torques, receiving a torque signal, comparing the torque signal to the acceptable range of torques, and stopping a motor if the torque applied by the motor is outside of the acceptable range of torques. The verification signal is indicative of the current drawn by the motor and the torque signal is indicative of torque applied by the motor.
Patent AU-2016283500-A1 (AU)
Title: Dry-cast lightweight veneer block, system, and method
Inventor: BROWNING LEONARD
IPC: E04F13/14
Filed: 2016-01-29
Abstract: Described are dry cast lightweight veneer blocks and a system and method of installing lightweight veneer blocks. The courses can be assembled without mortar between the courses. As an example, sides of the veneer blocks have areas that recede from an imaginary plane between adjacent veneer blocks to give a deep texturing and a shadow effect between veneer blocks. The installation system and method include a substrate, an air barrier applied to the substrate, a plurality of veneer blocks, and an adhesive applied between the plurality of veneer blocks and the air barrier.
Patent AU-2016303662-A1 (AU)
Title: Bacteria engineered to treat disorders involving propionate catabolism
Inventor: FALB DEAN
IPC: A61K35/74
Filed: 2016-07-29
Abstract: The present disclosure provides engineered bacterial cells comprising a heterologous gene encoding a propionate catabolism enzyme. In another aspect, the engineered bacterial cells further comprise at least one heterologous gene encoding a transporter of propionate or a kill switch. The disclosure further provides pharmaceutical compositions comprising the engineered bacteria, and methods for treating disorders involving the catabolism of propionate, such as Propionic Acidemia and Methylmalonic Acidemia, using the pharmaceutical compositions.
Patent AU-2016315858-A1 (AU)
Title: Power tool, battery pack, and combination, and method of controlling the same
Inventor: REED BRETT
IPC: H01M50/296
Filed: 2016-09-02
Abstract: A battery pack, power tool, and power tool combination. The battery pack includes one or more battery cells, a first terminal electrically connected to the one or more battery cells, a high current power supply terminal, a power switch electrically connected between the one or more battery cells and the high current power supply terminal, and a low current power supply terminal electrically connected to the one or more battery cells. The first terminal and low current power supply terminal are operable to provide a substantially continuous low current to the power tool during a normal operating state of the battery pack. The battery pack also includes a controller operable to control the power switch to provide high current power through the high current power supply terminal in response to a call for power from the power tool.
Patent AU-2016324352-A1 (AU)
Title: Intermodal container corner fitting connector
Inventor: MCKENZIE COLIN
IPC: B65D90/00
Filed: 2016-09-16
Abstract: A demountable connector assembly (10') for engaging an intermodal container corner fitting (4') including an elongate slot. The assembly includes a threaded shaft (12') having an attachment (14') for attaching a lifting line to lifting machinery; a lug (16') for conventionally engaging in the slot of the fitting; and a locking member (24'). The lug and locking member include respective alignment formations (20', 32') configured to impede relative rotation. The connector configured for rigid clamping engagement of the corner fitting between the lug and the locking member, by means of the shaft and threaded connections.
Patent AU-2016339652-A1 (AU)
Title: Temperature controlled water and oil filtering deep fryer
Inventor: SEAN TAM KIM SENG
IPC: A47J37/12
Filed: 2016-10-17
Abstract: The present invention provides a deep fryer that has both oil (101) and water (102) layer in contact with each other to enable fried impurities to sink to the water (102) layer. The fried impurities are filtered out using a mesh filter (131) and the water is pumped back into the water layer (102) after filtration. The temperature is fixed at a default setting, 180°C. The thermocouple will be automatically cut off when there is a drastic increase in the temperature of (oil 101) and water (102) layer. Alarm systems notify the user when the deep fryer is not working correctly. The whole fryer shuts down if there is a fault in the (pump 132) or temperature.
Patent AU-2016346892-A1 (AU)
Title: Synchronization protocol for multi-premises hosting of digital content items
Inventor: KOORAPATI NIPUNN
IPC: G06F17/30
Filed: 2016-10-11
Abstract: A synchronization protocol for multi-premises hosting of digital content items. In one embodiment, for example, a method comprises the operations of: detecting creation or modification of a content item; determining a content item namespace to which the content item belongs; obtaining a plurality of identifiers of a plurality of block servers to which the content item namespace is assigned; making a selection of one of the plurality of block servers as a target block server; and uploading any content item blocks of the content item to the target block server that are not already stored at the target block server.
Patent AU-2016347631-A1 (AU)
Title: Methods and systems for analyzing tissue quality using mid-infrared spectroscopy
Inventor: CHAFIN DAVID
IPC: G01N21/35
Filed: 2016-10-28
Abstract: A method of evaluating the quality state (such as a fixation status) of a cellular sample is provided. A MIR spectrum (220) of the sample is obtained, and a classification (211) or quantification (231) algorithm is applied to the MIR spectrum to identify features (221) indicative of the quality state and/or to classify the sample. The quality state may then be used to determine whether the sample is appropriate for an analytical method and/or whether remedial processing (such as further fixation) is appropriate.
Patent AU-2016384267-A1 (AU)
Title: Orvepitant for the treatment of chronic cough
Inventor: TROWER MIKE
IPC: A61K9/20
Filed: 2016-12-27
Abstract: This invention relates to the new use of the compound 2-(R)-(4-Fluoro-2-methyl-phenyl)-4- (S)-((8aS)-6-oxo-hexahydro-pyrrolo[1,2-a]-pyrazin-2-yl)-piperidine-1-carboxylic acid [1-(R)-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methylamideor pharmaceutically acceptable salts thereof and pharmaceutical compositions containing it for the treatment of chronic cough, particularly chronic cough due or associated with interstitial lung diseases (IDLs), including idiopathic pulmonary fibrosis (IPF), with lung tumours or with chronic obstructive pulmonary disease (COPD).
Patent AU-2016385130-A1 (AU)
Title: Method of fluid exchange and separation apparatus
Inventor: AURET DEREK
IPC: F28D11/06
Filed: 2016-12-24
Abstract: The invention relates to a method of fluid exchange using a separation apparatus, in controlled fluid communication with an inlet and an outlet. Opening of the inlet enables fluid communication with the separation apparatus, exchange of fluid (a "first fluid exchange") of a first volume of fluid, sealing/closing preventing further fluid communication. Opening of the outlet to be in fluid communication with the separation apparatus enables exchange of fluid (a "second fluid exchange") through the open outlet of a second volume of fluid. In the method, the outgoing volume of fluid and the incoming volume of fluid in each exchange are substantially similar and there is substantially no loss of pressure by virtue of the exchange. The invention also relates to a separation apparatus, including a separation chamber and a control system.
Patent AU-2016392719-A1 (AU)
Title: Therapeutic nanoparticles having EGFR ligands and methods of making and using same
Inventor: ZALE STEPHEN E
IPC: A61K49/08
Filed: 2016-08-19
Abstract: Provided herein in part is a therapeutic nanoparticle that includes a biocompatible polymer; a polymer -EGFR ligand conjugate, wherein the EGFR ligand is covalently bound directly or through a chemical linker to the polymer, and a therapeutic agent.
Patent AU-2016402338-A1 (AU)
Title: Combinational compositions and methods of use thereof
Inventor: LUCEY MICHAEL
IPC: A61K31/40
Filed: 2016-04-14
Abstract: Disclosed are compositions and methods for the treatment of a disease or disorder comprising i) at least one fatty acid, and ii) at least one cholesterol lowering compound. Compositions and methods of the disclosure reduce total cholesterol and maintain total cholesterol homeostasis.
Patent AU-2017200738-A1 (AU)
Title: Cooking apparatus
Inventor: SAMARTGIS JIM
IPC: A47J37/06
Filed: 2017-02-03
Abstract: Abstract A cooking apparatus for the cooking of bacon in a microwave oven, the apparatus including a base member and a lid which is removably co-operable therewith, wherein: the base member including a bottom and a peripheral side wall extending upwardly therefrom, the bottom of the base member having an inside cooking surface being of an arcuate shape when viewed in end elevation such that the cooking surface is higher at a centre portion of the arcuate shape than at an end portion, such that liquids can run from the centre portion to the end portion , the cooking surface of the base member further including a plurality of spaced-apart ribs extending substantially transversely thereof; and wherein the lid includes a top and a peripheral side wall extending therefrom, wherein the lid, when viewed in end elevation, curves from the top to the peripheral side wall.
Patent AU-2017202210-A1 (AU)
Title: Autoinjector system
Inventor: SLATE JOHN B
IPC: A61M5/20
Filed: 2017-04-04
Abstract: An injector for injecting a medicament into a patient includes a surface for removably mounting a removable cassette thereon, and a motor driven link having a first end engageable with a portion of the removable cassette when the removable cassette is mounted on the surface. The removable cassette has disposed therein a sleeve holding a syringe containing the medicament. The link is for moving the sleeve from a first position to a second position.
Patent AU-2017202289-A1 (AU)
Title: Methods and compositions for cns delivery of arylsulfatase a
Inventor: SALAMAT-MILLER NAZILA
IPC: A61K38/46
Filed: 2017-04-06
Abstract: The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an arylsulfatase A (ASA) protein, salt, and a polysorbate surfactant for the treatment of Metachromatic Leukodystrophy Disease.
Patent AU-2017203338-A1 (AU)
Title: Adjustable lap strap system
Inventor: CARINE DAVID SHAUN
IPC: B60R22/00
Filed: 2017-05-18
Abstract: The object to provide a child safety seat with which the user is able to restrain and fasten a child in a child safety seat in a optimal way is solved by the child safety seat with the five point harness accord 5 ing to the invention comprises a two tongue buckle, whereby the two tongue buckle comprises guiding means through which webbing is guided and the webbing comprises stopping means to allow a prede termined length of webbing to run through the guiding means and retracting means operatively con nected to at least one part of the webbing.
Patent AU-2017204083-A1 (AU)
Title: Controlled non-classified filling device and method
Inventor: PY DANIEL
IPC: B65B3/00
Filed: 2017-06-16
Abstract: An injection member penetrates an elastic septum of a device defining a sealed, empty, sterile chamber in fluid communication with the septum. During penetrating, an annular interface is formed between the septum and the injection member extending axially between a penetration point on an interior surface of the septum in fluid communication with the sterile chamber, and an exterior surface of the septum engaging the injection member. The injection member is de-contaminated by (i) friction between the septum and injection member at the annular interface, and (ii) elongation of the septum at the annular interface. A substance is introduced through the injection member and into the sterile chamber of the device, the injection member is then withdrawn from the septum, the septum reseals itself at the resulting penetration aperture, and the chamber is maintained sterile throughout the foregoing steps. FIG. 4 for publication co C"2 Lo Lo CI,2 q ":r coClQ--CO o,2 C112 CI%2 CO LO C11.2
Patent AU-2017204162-A1 (AU)
Title: Compositions and methods for stabilization of active agents
Inventor: KAPLAN DAVID L
IPC: A61K35/76
Filed: 2017-06-20
Abstract: The invention relates to storage-stable compositions comprising a silk fibroin matrix and an active agent distributed therein, wherein the active agent retains at least about 30% of its original bioactivity when the composition is subjected to at least one state-changing cycle, and/or is maintained for a period of time under a specified condition. In some embodiments the active agent is a vaccine, the state-changing cycle is a freeze-thaw cycle, the period of time for maintaining the active agent is at least about 24 hours, and the specified condition can be an environmental condition under which an active agent is stored and/or transported. The invention also relates to kits and delivery devices, e.g., useful in biomedical fields, utilising the above-mentioned compositions.
Patent AU-2017210617-A1 (AU)
Title: Methods and kits for detecting an infectious agent
Inventor: ZHANG AIGUO
IPC: C12Q1/70
Filed: 2017-08-04
Abstract: Abstract The present invention provides methods and kits for determining the presence, absence, or level of an infectious agent in a sample. Specifically, the present invention provides methods and kits for detecting or quantifying certain target polynucleotides of the infectious agent. In certain embodiments, the present invention provides for such detection without the need for amplification (e.g., replication) of the target molecule and/or without the need for labor intensive purification procedures. In certain embodiments, the present invention provides positive control and housekeeping gene for normalization and quantatively detection of the copy numbers of infectious agent in a sample. In these or other embodiments, the invention allows for such detection with the desired sensitivity and/or specificity, even where the polynucleotide is present in the sample at low copy number.
Patent AU-2017223606-A1 (AU)
Title: Sustained release buprenorphine microspheres (SRBM) and methods of use thereof
Inventor: VASISHT NIRAJ
IPC: A61K9/00
Filed: 2017-02-23
Abstract: The present invention is directed to a sustained release buprenorphine microsphere (SRBM) formulation capable of delivering buprenorphine, a metabolite, or a prodrug thereof for a duration of about 7 days to about 6 months.