baber/WOPTO huggingface dataset:
Patent DE-69514367-T2 (DE)
Inventor: IWASAWA YOSHIKAZU
IPC: C07D215/12
Filed: 1995-08-10
Granted: 2000-07-27
Abstract: The present invention relates to a compound of the formula (I): <CHEM> wherein Ar<1>, Ar<2> and Ar<3> represent an aryl group or a heteroaromatic ring group; A represents a hydrocarbon group which may be substituted; Q represents a group of the formula -(CH2)m- (m is an integer of from 1 to 6) or -(CH2)n-W-(CH2)p- (W is an oxygen atom, a sulfur atom, a vinylene group or an ethynylene group; n and p are a integer of from 0 to 3); R<1> represents a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, an aryl or heteroaromatic ring group which may be substituted; R<2>, R<7> and R<8> represent a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group or a lower alkoxy group; R<3> and R<4> represent a hydrogen atom, a halogen atom, a hydroxyl group, an amino group, a nitro group, a cyano group, a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, a lower alkyl group, a lower hydroxyalkyl group, a lower fluoroalkyl group or a lower alkoxy group; R<5> represents a lower alkyl group; and R<6> represents a hydrogen atom or a lower alkyl group, its pharmaceutically acceptable salt or ester, and an antitumor agent containing it as an active ingredient.
Patent DE-69518484-T2 (DE)
Inventor: KORBEL ANDRZEJ
IPC: B21J5/00
Filed: 1995-04-07
Granted: 2001-04-19
Abstract: PCT No. PCT/PL95/00006 Sec. 371 Date Jan. 30, 1996 Sec. 102(e) Date Jan. 30, 1996 PCT Filed Apr. 7, 1996 PCT Pub. No. WO95/32818 PCT Pub. Date Dec. 7, 1995An improvement to a method for plastic forming of a material by rolling, forging or extrusion, by using a tool to exert a force on the material to obtain a product of desired geometry. The improvement comprises inducing in the material a reversible plastic strain in the form of shear bands localized in a zone of most intense deformation by the tool, by introducing a motion of the tool additional to a tool working motion which produces the desired geometry. The additional motion is reversible and transfers motion to the material due to intimate contact between the material and the tool.
Patent DE-69518505-T2 (DE)
Inventor: PFAENDNER RUDOLF
IPC: C08L67/02
Filed: 1995-02-15
Granted: 2001-01-11
Abstract: PCT No. PCT/EP95/00541 Sec. 371 Date Aug. 28, 1996 Sec. 102(e) Date Aug. 28, 1996 PCT Filed Feb. 15, 1995 PCT Pub. No. WO95/23176 PCT Pub. Date Aug. 31, 1995A process is disclosed for increasing the molecular weight of polyesters, polyester copolymers or polyester blends, which comprises heating a polyester blended with a tetracarboxylic acid dianhydride and a sterically hindered hydroxyphenylalkylphosphonic acid ester or half-ester to above the melting point (glass transition temperature) of the polyester.
Patent DE-69524709-T2 (DE)
Inventor: BONAL DE FALGAS JOAQUIN
IPC: A61K31/275
Filed: 1995-02-06
Granted: 2002-08-08
Abstract: Products having formula (I) wherein R<2> is (C1-C4)-alkyl, (C1-C4)-acyl, CF3, Cl, Br or I; R<3> is H, (C1-C4)-alkyl, (C1-C4)-acyl, (C1-C4)-alcoxyl, CF3, F, Cl, Br, phenyl, OH, SH, NH2 or amino mono- or bisubstituted by (C1-C3)-alkyl; R<4> is (C1-C4)-alkyl, (C1-C4)-acyl, CF3, F, Cl, Br, I, carboxilo, (C1-C4)-alcoxycarbonyl, cyano, nitro or phenyl; and R<6> is H, (C1-C4)-alkyl, (C1-C4)acyl, CF3, Cl, Br or I, said products presenting, together with a low toxicity, a 5-lipoxigenase inhibiting activity much higher than that of benaprofene or ketoconazol. These characteristics make the disclosed derivates extremely useful for the preparation of drugs against leukotrien-mediated diseases, such as rheumatoid arthritis, ulcerative colitis, asthma, psoriasis and herpes. <CHEM>
Patent DE-69525366-T2 (DE)
Inventor: ROSENBAUM SUSAN
IPC: G01N33/534
Filed: 1995-10-30
Granted: 2002-11-07
Abstract: The present invention relates to a method for determining whether a compound is capable of binding to a BMP receptor kinase protein complex, the method comprising introducing a sample comprising the compound to the BMP receptor kinase protein complex and allowing the compound to bind to the BMP receptor kinase protein complex, wherein the BMP receptor kinase protein complex is comprised of a BMP type I receptor kinase protein and the BMP receptor kinase protein BRK-3. The invention further relates to a method for determining the concentration of a BMP receptor ligand in a clinical sample, the met-hod comprising introducing the sample comprising the ligand to a BMP receptor kinase protein complex and allowing the ligand to bind to the BMP receptor kinase protein complex, wherein the BMP receptor kinase protein complex is comprised of a BMP type I receptor kinase protein and BMP receptor kinase protein BRK-3. The invention further relates to a host cell co-transfected with an expression vector comprising a DNA sequence that codes for the BMP receptor kinase protein BRK-3 and an expression vector comprising a DNA sequence that codes for a BMP type I receptor kinase protein. The invention further relates to a host cell co-transfected with an expression vector comprising a DNA sequence that codes for a soluble or incomplete BMP type I receptor kinase protein and a soluble or incomplete BMP receptor kinsase protein BRK-3. The invention further relates to a method for determining whether a test compound produces a signal upon binding to a BMP receptor protein complex.
Patent DE-69535147-T2 (DE)
Inventor: SEED BRIAN
IPC: C12N15/33
Filed: 1995-09-08
Granted: 2007-07-05
Abstract: The invention features a synthetic gene encoding a protein normally expressed in mammalian cells wherein at least one non-preferred or less preferred codon in the natural gene encoding the mammalian protein has been replaced by a preferred codon encoding the same amino acid.
Patent DE-69601135-T2 (DE)
Inventor: ZAKAI AVI ZAKAI AVI
IPC: B60K15/035
Filed: 1996-01-09
Granted: 1999-05-20
Abstract: A roll over vent valve comprising: a housing (1) having a fluid inlet and a fluid outlet, the latter comprising a substantially elongated slit-like outlet aperture (6) of the housing bounded by a valve seating (5a). There is furthermore provided a float member (15) located in the housing and axially displaceable within the housing between the inlet and the outlet; an elongated flexible closure membrane strip (23) anchored at one end thereof to an end of the float member adjacent the outlet and at a portion thereof offset with respect to the outlet; spring biassing means (27) located within the housing and bearing on the float member so as to spring bias it in the direction of the outlet; whereby the spring biassing together with buoyancy forces acting on the float member tend to press the membrane strip into sealing engagement with the outlet aperture whilst gravity forces acting on the float member tend to displace the float member away from the outlet so as to progressively detach the strip from sealing engagement with the outlet. <IMAGE>
Patent DE-69606999-T2 (DE)
Inventor: BRAMMER JOHN
IPC: G06T5/00
Filed: 1996-06-07
Granted: 2000-10-05
Abstract: The invention provides an apparatus and method for obtaining an image by performing a logistic discriminant analysis on machine readable data derived from an imager, such that estimates of a logistic regression co-efficient are obtained. The logistic regression coefficient is used to estimate the probability of whether a pixel (or voxel) is of a first class type or second class type. It has been found that errors in categorising some types of data from some images do not fall into normal ("Gaussian") error groups, which was previously thought to be the case. Using the present invention, an improved categorisation of image data (especially at region boundaries) is obtained. The invention has applications in all types of image enhancement including, for example, satellite and aerial photography.
Patent DE-69612666-T2 (DE)
Inventor: WILF ITZHAK
IPC: H04N5/272
Filed: 1996-09-09
Granted: 2002-05-29
Abstract: Apparatus for automatic electronic replacement of a billboard in a video image including an automatic camera orientation measurement apparatus including motion measurement means operative to measure the Field of View (FOV) of the TV camera relative to a known reference position. <IMAGE>
Patent DE-69618125-T2 (DE)
Inventor: MARTIN WALLACE ANTHONY
IPC: B29C33/06
Filed: 1996-09-27
Granted: 2002-06-13
Abstract: The power insert (706) includes an annular flat surface surrounding the convex surface, defining at the junction therebetween a discontinuity of curvature, which imparts a sharp edge to the mold half formed thereby. The power insert may be constructed of pure steel, or alternatively, it may be made of brass, copper chromium, or cobalt-nickel alloyed martensitic steel. The power insert may be coated with a surface layer of nickel phosphor or silicone oxide, or chrome nitride. These layers may be turned to their proper thicknesses and dimensions by diamond cutters, and they may be thermally hardened. <IMAGE>
Patent DE-69620900-T2 (DE)
Inventor: SMALLEY E
IPC: D04H1/4242
Filed: 1996-09-06
Granted: 2003-07-24
Abstract: This invention provides a method of making single-wall carbon nanotubes by laser vaporizing a mixture of carbon and one or more Group VIII transition metals. Single-wall carbon nanotubes preferentially form in the vapor and the one or more Group VIII transition metals catalyzed growth of the single-wall carbon nanotubes. In one embodiment of the invention, one or more single-wall carbon nanotubes are fixed in a high temperature zone so that the one or more Group VIII transition metals catalyze further growth of the single-wall carbon nanotube that is maintained in the high temperature zone. In another embodiment, two separate laser pulses are utilized with the second pulse timed to be absorbed by the vapor created by the first pulse.
Patent DE-69624393-T2 (DE)
Inventor: ZAGARA MAURIZIO
IPC: A61M60/859
Filed: 1996-02-20
Granted: 2003-07-10
Abstract: A pumping device such as a cardiac assistance device comprises, inside a shell (12), a plate (22) which can cyclically squeeze a pumping bag (20) and an actuator for driving the plate (22). The actuator comprises a motor (24), preferably of the brushless type, with a rotor (28) located in a central position so as to drive a screw (106) which converts the rotary movement of the motor (24) into a reciprocating movement of the plate (22). The screw (106) is constructed in the form of a telescopic screw, preferably a ball-bearing screw. <IMAGE>
Patent DE-69633664-T2 (DE)
Inventor: KING MARY-CLAIRE
IPC: C07K14/82
Filed: 1996-04-19
Granted: 2006-02-23
Abstract: Specific BRCA1 mutations, PCR primers and hybridization probes are used in nucleic acid-based methods for diagnostic of inheritable breast cancer susceptibility. Additionally, binding agents, such as antibodies, specific for peptides encoded by the subject BRCA1 mutants are used to identify expression products of diagnostic mutations/rare alleles in patient derived fluid or tissue samples. Compositions with high binding affinity for transcription or translation products of the disclosed BRCA1 mutations and alleles are used in therapeutic intervention. Such products include anti-sense nucleic acids, peptides encoded by the subject nucleic acids, and binding agents such as antibodies, specific for such peptides.
Patent DE-69633936-T2 (DE)
Inventor: SUVANEN JYRI
IPC: H04Q7/32
Filed: 1996-06-07
Granted: 2005-11-10
Abstract: PCT No. PCT/FI96/00340 Sec. 371 Date Dec. 8, 1997 Sec. 102(e) Date Dec. 8, 1997 PCT Filed Jun. 7, 1996 PCT Pub. No. WO96/42142 PCT Pub. Date Dec. 27, 1996A method and device for eliminating acoustic echo in a digital mobile communications system, which system includes a mobile station and a fixed mobile network in which speech signal transmission occurs on a radio path in an uplink direction from the mobile station to the fixed mobile network, and in a downlink direction from the fixed mobile network to the mobile station, and in which a speech coding method is employed on the radio path. Acoustic echo is eliminated by: eliminating acoustic echo, in signals transmitted in the uplink direction, of signals transmitted in the downlink direction, by means of an echo canceller in the mobile station, and in the fixed mobile network, eliminating acoustic residual echo, in signals transmitted in the uplink direction, of signals transmitted in the downlink direction as follows: monitoring voice activity in signals transmitted in the downlink direction; monitoring whether a double-talk situation is present or not; replacing signals transmitted in the uplink direction with noise after a predetermined delay when detecting voice activity in signals transmitted in the downlink direction; terminating the replacing of signals transmitted in the uplink direction with noise after a predetermined delay when detecting the end of voice activity in signals transmitted in the downlink direction; and preventing signals transmitted in the uplink direction from being replaced with noise when a double-talk situation is detected.
Patent DE-69635583-T2 (DE)
Inventor: ARTHUN NILS
IPC: C12M1/26
Filed: 1996-10-18
Granted: 2006-08-10
Abstract: PCT No. PCT/SE96/01325 Sec. 371 Date May 4, 1998 Sec. 102(e) Date May 4, 1998 PCT Filed Oct. 18, 1996 PCT Pub. No. WO97/16715 PCT Pub. Date May 9, 1997The invention concerns a device for introduction and/or withdrawal of a medium into/form an apertured container, and it comprises at least one transfer (1) for transferring medium to or from the container, and at leant one seal. The seal is incorporated as a sealingly mounted part of the transfer member (1) and the transfer member (1) is by means of a fastening device (3), via the seal, sealingly secured to the container of a fastening device (3), via the seal, sealingly secured to the container aperture during use and them forms a closed system together with the container. The transfer member (1) is removable for replacement thereof after use and the seal has a sealable channel to interconnect the transfer member (1) and the container interior during use.
Patent DE-69637097-T2 (DE)
Inventor: MOLDT PETER
IPC: A61P25/28
Filed: 1996-10-11
Granted: 2007-09-20
Abstract: PCT No. PCT/EP96/04449 Sec. 371 Date May 18, 1998 Sec. 102(e) Date May 18, 1998 PCT Filed Oct. 11, 1996 PCT Pub. No. WO97/13770 PCT Pub. Date Apr. 17, 1997A compound having the formula, or any of its enantiomers or any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or 2-hydroxyethyl; and R4 is phenyl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl; 3,4-methylenedioxyphenyl; benzyl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl; heteroaryl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl; or naphthyl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl. The compounds possess valuable pharmaceutical properties as monoamine neurotransmitter re-uptake inhibitors.
Patent DE-69711328-T2 (DE)
Inventor: CLERC DENIS
IPC: B05D1/18
Filed: 1997-10-13
Granted: 2002-09-19
Abstract: The method involves applying, for example, a resin product to a continuously moving steel strip (7) so it receives a coating from pick-up (4) and applicator (5) rollers. A current is generated in the liquid in front of the coating zone to drive any air bubbles to the surface so they burst. The coating apparatus consists of a bath (2) for the coating liquid (3) which is fed continuously down a sloping surface (1), while the current is created by a roller (8) which is partially immersed in the liquid and turns in the same direction as the pick-up roller and at a speed which is between 5 and 15 per cent of that of the steel strip.
Patent DE-69712789-T2 (DE)
Inventor: GIESE O
IPC: A43B5/16
Filed: 1997-06-27
Granted: 2002-11-28
Abstract: A boot having a shoe shaped shell member and a cuff member having a section overlapping the shell member. The cuff and shell members are pivotally connected together for pivoting movement in response to pivoting of the individual's leg relative to the individual's foot. An elastomeric material is disposed between said shell member to pivotally connect the two members together.
Patent DE-69715983-T2 (DE)
Inventor: SOREL ALAIN
IPC: B26F1/02
Filed: 1997-07-11
Granted: 2003-08-14
Abstract: The stamping machine has a lower matrix stamping section (86) which is fixed on a moving chassis. Up to 24 stamping sections can be placed on the body. There is an upper tool support (50) for a stamping tool (62). A fixed holder (60) supports the stamping tool. The upper section positions the tool with respect to the support section and commands vertical movement of the tool in the support.
Patent DE-69726132-T2 (DE)
Inventor: BERNADINI RONALD
IPC: G07D7/00
Filed: 1997-02-05
Granted: 2004-07-22
Abstract: Method and apparatus for validating banknotes. In some countries, genuine banknotes are provided with a security thread embedded in the banknote, but partially exposes at regularly spaced regions along its length by windows. The windows have a width greater that the security strip itself. The increased transmissivity of the banknote in the infrared region is utilized to detect the presence of such windows to validate the banknote. If the required variation in transmissivity is not detected, the banknote can be rejected as a countefeit.
Patent DE-69733821-T2 (DE)
Inventor: SAVAGE R
IPC: G01N33/483
Filed: 1997-05-06
Granted: 2006-04-20
Abstract: The present invention is a sensor cartridge into which sensors are installed. The sensor cartridge allows the sensors to be easily and reliably installed into a blood analyzer. The sensor assembly has an electrical connector mounted on the rear side of the assembly. A plurality of inner walls within the housing locate a pump tube assembly and right angle fluid coupling within the housing. An opening in the housing receives a first boss which extends from the blood analyzer. A capture/release arm has an opening through which the first boss protrudes. The arm is resiliently held in place such that an inner edge of the opening is captured within a ring-like groove in the boss that extends from the blood analyzer when the cartridge is installed in the blood analyzer. A portion of the arm extends beyond the housing to allow an operator to press the arm and thus release the edge of the arm from the groove in the boss. Electrical contacts of the connector on the rear side of the sensor assembly are aligned to mating electrical contacts of the blood analyzer as the sensor assembly is being installed by alignment of the boss which extends from the blood analyzer to mate with the boss which extends from the housing, and alignment of two male fluid connectors. Accordingly, the electrical contacts of the sensor assembly will be in close alignment with the electrical contacts of the blood analyzer as the contacts approach one another.
Patent DE-69800210-T2 (DE)
Inventor: SALSARULO ODETTE
IPC: A61K9/16
Filed: 1998-10-06
Granted: 2001-03-15
Abstract: Compositions containing anhydrous lactulose in an anhydrous coating material comprising pharmaceutically pure paraffin hydrocarbons having a melting point of 37 plus or minus 4 degrees C. Independent claims are also included for: (1) an anhydrous laxative medicament, without water for oral administration comprising the above composition; and (2) a process for the preparation of the anhydrous laxative medicament containing a lactulose base comprising, to be ingested without water by the patients, with a mixture of pure pharmaceutically acceptable paraffin hydrocarbons as above.
Patent DE-69807424-T2 (DE)
Inventor: YAMADA KOHZABUROH
IPC: G03C1/06
Filed: 1998-11-24
Granted: 2003-04-03
Abstract: A thermographic recording element having an image forming layer contains an organic silver salt, a reducing agent, an optional photosensitive silver halide, and a specific nucleating agent. The element has high Dmax, high sensitivity, satisfactory contrast, low fog, and minimal dependency of photographic properties on developing temperature.
Patent DE-69812794-T2 (DE)
Inventor: LA ROSA GIACOMO
IPC: B60T7/06
Filed: 1998-07-21
Granted: 2004-02-12
Abstract: The object of this invention is a locking device for the brake pedal (10) of a vehicle to the pressure rod (15) of the power brake, of the type in which the pressure rod forms a spheric end (14) and the pedal bears a substantially spheric end (13) and quick-mount elastic means are provided (20a,20b) ensuring the release-type fastening of the spheric end (14) to the pedal (10) in a spheric joint type configuration. The elastic means (20a,20b) are part of an interchangeable insert (17) equipped with means (18a,18b) for quick interchangeable locking to the pedal, insert (17) is an open-ring shaped insert, with a longitudinal opening (21) allowing pressure rod release in a direction perpendicular to the pressure rod axis. <IMAGE>
Patent DE-69815533-T2 (DE)
Inventor: DOBRIN CHRISTOPHER
IPC: A61F5/44
Filed: 1998-02-27
Granted: 2004-05-13
Abstract: A disposable absorbent article having a breathable laminate backsheet. The absorbent article has a front waist region, a rear waist region, a crotch region positioned between the front waist region and the rear waist region, a pair of opposed side edges, a first end edge and a second end edge. The absorbent article includes an absorbent core having a pair of opposing longitudinal edges, a garment-facing side and a body-facing side, and a breathable laminate backsheet disposed adjacent to the garment-facing side of the absorbent core. The breathable laminate backsheet has an inner layer and an outer layer joined to one another. The inner layer is positioned between the absorbent core and the outer layer. The outer layer is relatively vapor pervious. The inner layer is substantially liquid, vapor and air impermeable. The inner layer is longitudinally coterminous with the absorbent article and of a smaller transverse width than the front waist region, the rear waist region, and the crotch region so as to form a breathable zone which is longitudinally coterminous with the absorbent article and adjacent to each of the side edges.
Patent DE-69818189-T2 (DE)
Inventor: KUDER JAMES E
IPC: B32B7/12
Filed: 1998-10-14
Granted: 2004-06-03
Abstract: Multilayer films that include a thermotropic liquid crystalline polymer film layer and a poly(ethylene terephthalate) or polycarbonate film layer are bound together using a hot melt adhesive, Which may be either (1) a blend of poly( alpha -olefins) that includes isotactic polypropylene, a polymer of a second lower poly( alpha -olefin), and a small amount of a higher poly( alpha -olefin); or (2) a polyamide-based hot melt adhesive.