baber/WOPTO huggingface dataset:
Patent RU-2692604-C1 (RU)
Inventor: KOLPAKOV SERGEJ ANATOLEVICH
IPC: C12N7/00
Filed: 2018-08-15
Granted: 2019-06-25
Abstract: Изобретение относится к области биотехнологии. Изобретение представляет собой способ адаптации ротавируса человека группы А к росту на перевиваемых культурах клеток животных, заключающийся в том, что адаптацию и последующее культивирование ротавируса человека группы А проводят путем последовательных пассажей на смешанной культуре, состоящей из эпителиоидного и фибробластного типов клеток в соотношении 1:1; в качестве клеток эпителиоидного ряда используют перевиваемую культуру клеток почки эмбриона свиньи (СПЭВ), фибробластного типа - перевиваемую культуру фибробластов крысы (ФК), выращенные раздельно на среде 199; полученный монослой клеток обоих типов снимают со стекла смесью раствора Версена и 0,25% раствора трипсина в соотношении 5:1, разводят средой 199 в 4 раза, смешивают при соотношении культур клеток 1:1, добавляют 10% прогретой сыворотки крупного рогатого скота, выдерживают в термостате при +37°С в течение 2 суток; отмывают 3-кратно монослой смеси клеток от ростовой среды раствором Хенкса, добавляют 0,5 мл обработанной раствором трипсина (20 мкг/мл) 10% фекальной суспензии, содержащей ротавирус человека, и контактируют в течение 10 мин; добавляют поддерживающую среду 199 без сыворотки до первоначального объема и выдерживают в термостате при +37°С в течение 10 суток; замораживают при -18-20°С в течение 5 ч с последующим оттаиванием при 37°С, повторяя процедуру трижды; последующие пассажи проводят по той же схеме, используя инокулят предыдущего пассажа. Изобретение позволяет получить стабильно растущие на перевиваемых культурах клеток штаммы ротавируса человека группы А с концентрацией вирусных частиц не менее чем 1⋅10в 1 мл. культуральной жидкости, имеющие типичную морфологию ротавирусных частиц и двунитевую сегментированную РНК. 1 табл., 3 ил.
Patent RU-2698409-C1 (RU)
Inventor: Melnik Sergej Vladislavovich
IPC: G01C21/00
Filed: 2018-09-06
Granted: 2019-08-26
Abstract: FIELD: signaling devices. 
     SUBSTANCE: invention relates to the field of signaling devices, namely devices, which signal the location of the moving object with transmission of signals to the central station, and can be used for monitoring movement of vehicles and cargo, passengers and service personnel of vehicles, personnel of enterprises, as well as persons whose movement is subject to control. To achieve the result, the system comprises a central server of the complex, at least one user workstation, at least one complex reference node, at least two spatially spaced high-frequency wireless readers, at least one low-frequency radiator, as well as radio tags. 
     EFFECT: technical result achieved when implementing the developed system consists in enabling fast search of moving objects, as well as movable property on the territory of hazardous production facilities and classified facilities using active radio frequency identification systems. 
     3 cl
Patent RU-2706349-C1 (RU)
Title: Active part cooled by fluid medium, electric machine and drive system
Inventor: BURGHARD MATTHIAS JOHANNES
IPC: H02K3/24
Filed: 2017-01-24
Granted: 2019-11-18
Abstract: FIELD: electrical equipment. 
     SUBSTANCE: invention relates to the electrical equipment. Active part of the machine is made in the form of a hollow cylinder having axially extending grooves, at least one electric conductor that is located in the corresponding groove and consists of several partial conductors. Main insulation is located between the conductor and the groove. Besides, the insulation surrounds the partial conductor. Cooling channel is located between main insulation and insulation of partial conductor. Main insulation covers the greater part of the bottom and two walls of the groove. In the groove, at least two electric conductors are located one above the other in radial direction. There is a shell of conductor that surrounds it in plane perpendicular to axial direction. At that, both the groove in the zone of the lower electric conductor and the shell of the lower electric conductor are narrowed towards the groove bottom so that the bottom conductor shell is fixed with geometrical closure in the groove bottom direction, and between the bottom of the groove and said shell there remains the first axially passing hollow space for the first inlet channel. 
     EFFECT: higher reliability. 
     21 cl, 13 dwg
Patent RU-2695950-C1 (RU)
Title: Ultrasonic inspection method of metal products defectiveness
Inventor: Bolotina Irina Olegovna
IPC: G01N29/04
Filed: 2018-12-14
Granted: 2019-07-29
Abstract: FIELD: physics. 
     SUBSTANCE: use: for flaw detection of complex shaped metal products. Summary of invention consists in the fact that with method for ultrasonic inspection of defectiveness of metal articles involves measurement of a two-dimensional surface profile of an article using an electric probe, selecting three reference points on distinct angles of the control article. Coordinates of said points are recorded and position of control item in space is determined. An optical 3D-scanner is used to project a regular grid of the scanner on a control product, fix it and form a computer form of the control item in form of 3D model of the control product and store it. Roughness of the article is measured using a profilometer. All measured values are recorded. Based on all obtained data, step and trajectory of ultrasonic sensor movement along control article surface are set. As a binder in an ultrasonic transducer, a matching layer and an elastic immersion layer are successively arranged in front of the ultrasonic piezoelectric transducer and selected based on the obtained roughness value. To select material of matching layer its specific acoustic resistance is determined. Thickness of matching layer is determined by formula. Using an ultrasonic sensor, tightly pressing the immersion material to the control article, ultrasonic signals are measured at preset points of the trajectory on the surface of the inspection item through each step of moving the ultrasonic sensor, recording the time of passage of transmitted and reflected ultrasonic signals in the volume of the control article, amplifying these signals and composite A- and C-images are formed, on the basis of which a three-dimensional image of the defect is created and visualized, the defect is determined from the value and position of its position in the control item. 
     EFFECT: technical result is possibility of ultrasonic inspection of metal products with complex shape. 
     1 cl, 9 dwg
Patent RU-2705720-C1 (RU)
Inventor: ANTSEV GEORGIJ VLADIMIROVICH
IPC: B63B19/14
Filed: 2018-12-21
Granted: 2019-11-11
Abstract: Изобретение относится к области судостроения, в частности к оборудованию судов шахтами больших размеров с водонепроницаемыми закрытиями со стороны днища. Днищевое закрытие шахты судна содержит балластируемую крышку в виде пустотелого понтона, служащую для перекрытия проема шахты. Крышка одной стороной прикреплена к днищу судна с помощью выступающего за плоскость днища шарнира, обеспечивающего плотное прилегание крышки к комингсу шахты при закрытии и к днищу судна при открытии шахты. Крышка разделена на две отдельные балластируемые емкости диагональной переборкой, расположенной в плоскости подвеса при вертикальном положении крышки. Открытие и закрытие шахты происходит из исходного вертикального положения забалластированной крышки, свободно висящей на шарнире. При продувке той или иной емкости крышка из вертикального положения поворачивается в сторону продутой емкости, и при последующем продувании воздухом другой емкости обеспечивается быстрый и однозначный переход крышки под действием сил плавучести в требуемое положение - в положение «открыто» или «закрыто». Положению «открыто» соответствует положение крышки, прижатой к обшивке днища по другую сторону от шахты относительно шарнира под действием сил плавучести. Положению «закрыто» соответствует положение крышки, прижатой к комингсу шахты также под действием сил плавучести. Достигается улучшение эксплуатационных характеристик заявляемого устройства в части надежности и безопасности в условиях волнения моря. 3 з.п. ф-лы, 2 ил.
Patent RU-2695975-C1 (RU)
Title: Method for effective rescue of victims in case of fire and during smoke-down
Inventor: ZHUKOV SERGEJ VLADIMIROVICH
IPC: A62B3/00
Filed: 2018-12-27
Granted: 2019-07-29
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to medicine, namely to medicine of catastrophes. Method comprises placing in building wall cabinets with self-contained marking devices and completing brigades of search and rescue units by search devices, wherein the marking device has a pulse oximeter connected to the radio signal supply unit, wherein there are several pre-selected radio signal versions, which indicate sufficient saturation with capillary blood oxygen, reduced saturation with capillary blood oxygen, wherein the marking device is automatically disconnected 30 minutes after the pulse recording is stopped in the person wearing the marking device, the search device has a screen on which the floor plan of the building is reflected with colour markings of the operating marking devices depending on the type of their signal, and the order of search and evacuation of personnel affected by rescue units is carried out depending on the level of oxygen saturation of capillary blood of each victim, marked on the search device. 
     EFFECT: invention can be used to increase efficiency of rescue operations in fire or smoke fires. 
     1 cl
Patent RU-2714488-C1 (RU)
Title: Method and device for measuring deviation of a process channel of a nuclear reactor
Inventor: Gurin Denis Aleksandrovich
IPC: G01B5/20
Filed: 2019-01-15
Granted: 2020-02-18
Abstract: FIELD: nuclear physics and equipment. 
     SUBSTANCE: group of inventions relates to means of checking and monitoring process channel pipes in nuclear installations in operation. Method of measuring deviation of process channel of channel nuclear reactor with installed fuel assembly consists in placing flexible rod element equipped with deformation sensors in hole of central tube of fuel assembly, with subsequent registration of bending of flexible rod element. Deformation transducer used is rod arranged offset from center of flexible rod element. Registration of flexible rod element is carried out by measurement of value of longitudinal movement of free end of bar fixed on one side. There is also a device for measuring. 
     EFFECT: group of inventions enables to determine the fact of bending, its shape with high sensitivity and at different height of process channel without the need to unload channel from fuel assembly. 
     11 cl, 3 dwg
Patent RU-2721480-C1 (RU)
Inventor: Prokhorovich Vladimir Evgenevich
IPC: G01N29/26
Filed: 2019-03-05
Granted: 2020-05-19
Abstract: FIELD: methods and devices for metal processing. 
     SUBSTANCE: invention can be used for quality control of welded joints. Essence of the invention consists in the fact that the automated system for monitoring the quality of welded joints comprises clamps for its attachment to the controlled article, a scanning head, mechanism for displacement of a detonation head, a system for supply of contact liquid, which includes a container with contact liquid, a pump and a tube, remote flaw detection equipment, and equipment for powering, controlling, processing and recording information, connected to a distortive head, a pump and electric motors of movement mechanism by electric cables, wherein it is equipped with a cylindrical housing with a sealing ring on the end surface, in the upper part of the cylindrical surface of the housing a ventilation hole is made, in the upper and lower parts of the cylindrical surface of the housing there are installed sensors of contact liquid presence, mechanism of distortion head movement is made in form of shaft passing in axial hole of flat part of housing through sliding bearing with magneto-liquid seal, from outer side of housing shaft is rigidly connected to reduction gear, and electric motor, which controls reduction gear, is made reversible and comprises a turning angle sensor, on the housing inner side on the shaft a lever is mounted, on the end of which a detective head is fixed in the form of a separate-combined piezoelectric transducer with an elongated acoustic screen, connected by electric cable passing through hollow channels of lever and shaft with remote flaw detection equipment and power supply equipment, control, processing and recording of information, the following components are arranged in series on the shaft: shaft thickening, resilient element and sliding bearing, on which with the possibility of rotation and movement in axial direction there is a plug with magneto-liquid seal, plug is made in form of rigid shaped disc with elastic sealing ring along its perimeter, on end of shaft on plug side locking nut is made, tube for supply of contact liquid connects pump with lower part of housing, pump is additionally made with possibility of pumping contact liquid from container with contact liquid into housing and back. 
     EFFECT: technical result is increased reliability and efficiency of circular weld seams control. 
     1 cl, 1 dwg
Patent RU-2691374-C1 (RU)
Inventor: BOKERIYA LEONID ANTONOVICH
IPC: A61B17/00
Filed: 2019-03-21
Granted: 2019-06-11
Abstract: Изобретение относится к медицине, а именно кардиохирургии. Выполняют мобилизацию легочной артерии с последующим пересечением посередине легочного ствола и формированием проксимального конца легочного ствола, расположенного ближе к клапану легочной артерии, и дистального конца, расположенного ближе к участку бифуркации. Иссекают фрагмент задней стенки левого предсердия в виде площадки с впадающими в нее устьями правых и левых легочных вен. Посредством сосудистых протезов соединяют проксимальный конец легочного ствола с площадкой задней стенки левого предсердия с устьями легочных вен, дистальный конец легочного ствола - со стенкой левого предсердия. Способ позволяет создать условия для адекватной газообменной функции легких при хирургическом лечении пациентов с выраженными анатомическими изменениями легочных артерий. 2 ил., 1 табл., 3 пр.
Patent RU-2704788-C1 (RU)
Title: Method for predicting left ventricular myocardial mass index in workers of chemical production depending on systolic blood pressure and low density lipoprotein concentration
Inventor: Gimaeva Zulfiya Fidaievna
IPC: G01N33/48
Filed: 2019-04-19
Granted: 2019-10-30
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to medicine, namely to cardiology and occupational diseases, and can be used for prediction of left ventricular myocardial hypertrophy. Age (Age), systolic arterial pressure (SAP), waist circumference (WC) and concentration of low density lipoproteins (LDLP) in blood serum are determined. Obtained anamnestic data and the survey results are inserted into the developed mathematical model. 
     EFFECT: method enables higher accuracy and reliability of the prediction by evaluating the complex of the most significant indicators. 
     1 cl, 1 dwg, 3 tbl, 3 ex
Patent RU-2700565-C1 (RU)
Title: Method for determining predisposition to developing obesity in children in conditions of excessive contamination with aluminum
Inventor: DOLGIKH OLEG VLADIMIROVICH
IPC: G01N33/58
Filed: 2019-06-06
Granted: 2019-09-19
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to medicine, particularly to paediatrics and endocrinology, and aims at determining predisposition to developing obesity in children in conditions of excessive contamination with aluminum. Blood and urine samples are taken in a child. Urine sample is used to determine content of aluminum, and blood serum – IgG level to aluminum. DNA of buccal epithelium is extracted. On the detecting amplifier using polymerase chain reaction in real time genotyping of MTNR1B (rs 10830963) and SIRT1 (rs 7069102) gene polymorphism is carried out. At simultaneous detection of the following diagnostic criteria: presence of variant homozygous or heterozygous genotypes of gene MTNR1B (rs 10830963) and gene SIRT1 (rs 7069102) under condition of simultaneous excess of aluminum concentration in urine by more than 2 times compared to reference level of aluminum content in urine, as well as when the physiological norm of IgG level to aluminum is exceeded in comparison with the upper limit, a conclusion is made on the child's propensity to develop obesity in conditions of excessive contamination with aluminum. 
     EFFECT: invention provides reliable assessment of aluminum effect on predisposition of manifestations of endocrine disorders in the form of obesity. 
     1 cl, 2 tbl, 2 ex
Patent RU-2721406-C1 (RU)
Title: Medicinal complex for treating type 2 diabetes and diabetic dyslipidemia
Inventor: PARK KI SOOK
IPC: A61K31/519
Filed: 2017-11-15
Granted: 2020-05-19
Abstract: FIELD: medicine; pharmaceuticals.SUBSTANCE: invention refers to medicine and pharmacy. Disclosed is a combined medicinal preparation for treating type 2 diabetes and dyslipidemia in diabetic patients, comprising a peptidase IV inhibitor gemigliptin or its salt, an inhibitor of HMG-CoA reductase, rosuvastatin or its salt and an excipient of calcium hydrophosphate dihydrate.EFFECT: technical result: invention provides effective control of blood sugar levels and reduced risk factors of cardiovascular diseases; wherein calcium hydrophosphate dihydrate (trade name DI-TAB, Innophos) plays the role of stabilizer of both active ingredients, gemigliptin (unstable under alkaline conditions) and rosuvastatin (stable in alkaline conditions and unstable in acidic conditions, therefore in usual dosage forms a strong base is often used as its excipient).11 cl, 2 dwg, 28 tbl
Patent RU-2713400-C1 (RU)
Title: Method of producing 5r-[(benzyloxy)amino]piperidine-2s-carboxylate and oxalates thereof
Inventor: WANG BAOLIN
IPC: C07D211/60
Filed: 2018-03-02
Granted: 2020-02-05
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to methods of producing 5R-[(benzyloxy)amino]piperidine-2S-carboxylate and its oxalate, where L-glutamic acid or sodium salt of L-glutamic acid as a starting material is reacted with monochloroacetic acid under alkaline conditions by a substitution reaction to obtain N-carboxymethyl-L-glutamic acid (compound III), then compound III is reacted with an alcohol in the presence of an acid reagent through an esterification reaction to obtain a diester of N-alkoxycarbonylmethyl-L-glutamic acid (compound IV), under action of a strong base, compound IV is subjected to intramolecular condensation to form a ring, hydrolysis with decarboxylation and esterification to obtain piperidin-5-one-2S-carboxylate (compound V), compound V is condensed with a hydrochloride salt of benzyloxyamine in the presence of an alkali to obtain 5-[(benzyloxy)imino]piperidine-2S-carboxylate (compound VI), compound VI is subjected to reduction and chiral separation to obtain 5R-[(benzyloxy)amino]piperidine-2S-carboxylate (IIb) oxalate, which is then neutralized to obtain 5R-[(benzyloxy)amino] piperidine-2S-carboxylate (IIa). Obtained 5R-[(benzyloxy)amino]piperidine-2S-carboxylate (IIa) or oxalate 5R-[(benzyloxy)amino]piperidine-2S-carboxylate (IIb) is used to obtain avibactam (I). 
     EFFECT: use of an inexpensive and readily available starting material which is characterized by high selectivity and is environmentally friendly and environmentally friendly during the production process. 
     10 cl, 3 dwg, 17 ex
Patent RU-2719656-C1 (RU)
Title: Способ прогнозирования развития ранней анемии недоношенных тяжелой степени, требующей проведения гемотрансфузии
Inventor: Kuzmenko Galina Nikolaevna
IPC: A61B5/00
Filed: 2019-07-09
Granted: 2020-04-21
Abstract: Изобретение относится к медицине, а именно к неонатологии, педиатрии и гематологии, и может использоваться для прогнозирования развития в первый месяц жизни у глубоконедоношенных детей, родившихся с массой тела менее 1500 г, ранней анемии недоношенных тяжелой степени, требующей проведения гемотрансфузии. В периферической венозной крови на 3-5 день жизни определяют содержание белка-3, связывающего инсулиноподобный фактор роста, измеряют вес ребенка при рождении и вычисляют прогностический индекс D по оригинальной расчетной формуле. При D более 0 прогнозируют развитие в первый месяц жизни ранней анемии недоношенных тяжелой степени, требующей проведения гемотрансфузии, а при D менее 0 прогнозируют отсутствие развития ранней анемии недоношенных тяжелой степени, требующей проведения гемотрансфузии. Способ позволяет среди глубоконедоношенных новорожденных с массой тела менее 1500 г выделить группу риска по развитию в первый месяц жизни ранней анемии недоношенных тяжелой степени, требующей проведения гемотрансфузии, и своевременно проводить профилактические мероприятия, что улучшит показатели здоровья и качества жизни этих детей. 1 табл., 2 пр.
Patent RU-2720350-C1 (RU)
Title: Способ производства термообработанного стального листа
Inventor: BONNET FREDERIC
IPC: C21D9/573
Filed: 2017-12-20
Granted: 2020-04-29
Abstract: Изобретение относится к способу производства термообработанного стального листа, имеющего на линии термообработки химический состав стали и микроструктуру m, содержащую от 0 до 100% по меньшей мере одной фазы, выбранной из феррита, мартенсита, бейнита, перлита, цементита и аустенита. Способ включает: А) подготовительный этап, включающий: 1) субэтап выбора, на котором сравнивают химический состав и микроструктуру mс перечнем предварительно определенных продуктов; 2) субэтап расчета, на котором производят расчет по меньшей мере двух тепловых режимов TP, каждый из которых TPсоответствует микроструктуре m, полученной в конце TP, при этом расчет производят, исходя из выбранного продукта на этапе А.1) и TРи m, для получения m; 3) субэтап выбора, на котором выбирают один тепловой режим TPдля получения микроструктуры m, при этом режим TPвыбирают из TPи выбирают так, чтобы микроструктура mбыла получена в максимальной степени близкой к m; В) этап термообработки, на котором на стальном листе реализуется режим TP. Изобретение позволяет обеспечить индивидуальную термообработку каждого стального листа, которая сопровождается коротким промежутком времени расчета. 17 з.п. ф-лы, 5 ил.
Patent RU-2719294-C1 (RU)
Inventor: BALDEMAIR ROBERT
IPC: H04L5/26
Filed: 2017-12-20
Granted: 2020-04-17
Abstract: FIELD: physics.SUBSTANCE: invention relates to a method for use in a wireless device in a wireless communication system for transmitting uplink control information (UCI). Method comprises obtaining UCI containing a number of UCI-bits, converting UCI-bits into a set of modulation symbols, obtaining a configuration of resources, wherein the resource configuration is at least indicative of one or more allocated resources available for transmitting modulation symbols, converting modulation symbols to a resource configuration, wherein the resource configuration further indicates dedicated subcarriers contained in one or more allocated resources, and transmission of modulation symbols using the allocated subcarriers.EFFECT: technical result consists in reduction of number of PUCCH-formats associated with various users.16 cl, 15 dwg