baber/WOPTO huggingface dataset:
Patent EP-2015758-B1 (EP)
Inventor: BHANOT SANJAY
IPC: C12N15/113
Filed: 2007-05-07
Granted: 2014-04-02
Abstract: The present disclosure describes short antisense compounds, including such compounds comprising chemically-modified high-affinity monomers 8-16 monomers in length. Certain such short antisense compound are useful for the reduction of target nucleic acids and/or proteins in cells, tissues, and animals with increased potency and improved therapeutic index. Thus, provided herein are short antisense compounds comprising high-affinity nucleotide modifications useful for reducing a target RNA  in vivo.  Such short antisense compounds are effective at lower doses than previously described antisense compounds, allowing for a reduction in toxicity and cost of treatment. In addition, the described short antisense compounds have greater potential for oral dosing.
Patent EP-2097385-B1 (EP)
Inventor: BUNGARD CHRISTOPHER J
IPC: A61K31/416
Filed: 2007-10-23
Granted: 2012-08-01
Abstract: The present invention is directed to 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives of formula I (I) as glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.
Patent EP-2082019-B1 (EP)
Title: Solution de nettoyage de graffitis comprenant un concentré aqueux et une solution aqueuse diluée
Inventor: DECKER JAMES
IPC: C11D3/20
Filed: 2007-10-01
Granted: 2012-05-23
Abstract: La présente invention concerne une solution de nettoyage concentrée non aqueuse ayant une longue durée de conservation comportant un ester et un tensioactif anhydre. L'ester est le principe actif pour dissoudre un graffiti, de la graisse et d'autres contaminants. L'ester peut être un ou un mélange de glutarate de diméthyle, succinate de diméthyle, adipate de diméthyle, lactate d'éthyle, et un ester de méthyle extrait de l'huile de soja. Le tensioactif anhydre est, de préférence, un éthoxylate d'alcool. L'ester dans la solution concentrée ne se dégrade pas en un acide et alcool aussi longtemps que la solution n'est pas mélangée avec de l'eau. Cela permet le transport et le stockage du concentré tout en préservant son efficacité. Le concentré peut être dilué avec de l'eau immédiatement avant son utilisation. La dilution avant utilisation rend la solution de nettoyage de graffitis moins cher et empêche l'endommagement de surfaces sensibles mais ne permet pas un temps suffisant pour la dégradation de l'ester.
Patent EP-2092442-B1 (EP)
Inventor: BERNHARD BENJAMIN K D
IPC: G06F11/20
Filed: 2007-11-08
Granted: 2012-01-11
Abstract: A cluster recovery process is implemented across a set of distributed archives, where each individual archive is a storage cluster of preferably symmetric nodes. Each node of a cluster typically executes an instance of an application that provides object-based storage of fixed content data and associated metadata. According to the storage method, an association or “link” between a first cluster and a second cluster is first established to facilitate replication. The first cluster is sometimes referred to as a “primary” whereas the “second” cluster is sometimes referred to as a “replica.” Once the link is made, the first cluster's fixed content data and metadata are then replicated from the first cluster to the second cluster, preferably in a continuous manner. Upon a failure of the first cluster, however, a failover operation occurs, and clients of the first cluster are redirected to the second cluster. Upon repair or replacement of the first cluster (a “restore”), the repaired or replaced first cluster resumes authority for servicing the clients of the first cluster. This restore operation preferably occurs in two stages: a “fast recovery” stage that involves preferably “bulk” transfer of the first cluster metadata, following by a “fail back” stage that involves the transfer of the fixed content data. Upon receipt of the metadata from the second cluster, the repaired or replaced first cluster resumes authority for the clients irrespective of whether the fail back stage has completed or even begun.
Patent EP-2124686-B1 (EP)
Inventor: CHAMEROY ERIC
IPC: A47J27/08
Filed: 2007-12-26
Granted: 2010-08-25
Abstract: The appliance (1) has a flexible cover (3) movably fixed to a bowl (2) between a closed position, in which the bowl and the cover form a sealed cooking chamber, and an open position in which the cover allows communication of interior of the chamber with exterior. A control unit (5) controls movement of the cover between the closed and open positions, and has a force transmitting piece (5A) pivotably mounted along an axis (Y-Y'), where the cover is suspended to the piece in a hooking zone (P). An adjusting unit (23) varies a distance (D) separating the zone from the axis.
Patent EP-1997510-B1 (EP)
Inventor: SOEHNGEN MARIOLA
IPC: A61K38/46
Filed: 2002-10-31
Granted: 2012-02-29
Abstract: Use of a plasminogen activating factor (A) for treatment of stroke, where the activity of (A) is increased by more than 650 fold in presence of fibrin, is new. Independent claims are also included for the following: (1) tissue plasminogen activator (tPA) having an autolysis loop that includes His420, Asn421, Ala422 and Cys423; (2) urokinase having an autolysis loop that includes Val420, Thr421, Asp422 and Ser423; and (3) pharmaceutical composition containing (A) and at least one other medically active agent, or their salts. ACTIVITY : Cerebroprotective. No biological data is given. MECHANISM OF ACTION : None given.
Patent EP-2145986-B1 (EP)
Inventor: MIDDEKE HERMANN-JOSEF
IPC: C25D5/14
Filed: 2008-07-15
Granted: 2010-03-24
Abstract: To electroplate a metal layer which has silica particles dispersed therein, a solution and a method for electrochemically depositing a metal on a substrate are provided, wherein the solution contains ions of the metal to be deposited and silica particles, wherein at least one silicon containing organic moiety is provided to said silica particles , said silicon containing organic moiety comprising at least one functional group selected from the group comprising amino, quaternized ammonium, quaternized phosphonium and quaternized arsonium which imparts the silica particles a positive electric charge while being in contact with the solution.
Patent EP-2159524-B1 (EP)
Inventor: AOKI HIROSHI
IPC: F25D27/00
Filed: 2008-08-27
Granted: 2010-12-01
Abstract: The present invention refers to a refrigerator. The refrigerator comprises a heat-insulating main body having openings in a front side, as well as a divider creating a first storage compartment and a second storage compartment, by dividing inside of the heat-insulating main body into the first storage compartment and the second storage compartment arranged side by side. It is further provided a lighting unit which is embedded in a part of an internal side wall close to at least one of the openings of the first and second storage compartments, the lighting unit having a light-emitting diode as a light source. A base is provided on the part of the internal side wall in which the lighting unit is embedded, wherein the base includes a board which is fixed to the base to hold the light-emitting diode of the lighting unit.
Patent EP-2044836-B1 (EP)
Inventor: KOOPMANS WIEGER JAN
IPC: A22C13/00
Filed: 2008-10-02
Granted: 2011-06-08
Abstract: The invention relates to a method for coating a cheese, wherein an aqueous coating composition is applied to a surface of the cheese, said coating composition comprising a mixture of 70-98 parts by weight of a polymer A and 2-30 parts by weight of a polymer B, based on the total weight of the mixture, wherein polymer A has a glass transition temperature T g (A) of 25°C or less and wherein polymer B has a glass transition temperature T g (B) greater than 25°C, and wherein polymer A and polymer B are prepared by polymerization of a monomer or a monomer mixture, wherein the monomer is selected from the group consisting of a vinylic ester of an aliphatic saturated monocarboxylic acid having a chain length of C 1 -C 18 , a diester of an alkanol having a chain length of C 1 -C 18  and a monoethylenically unsaturated C 2 -C 12  dicarboxylic acid, an acrylic ester of an alkanol having a chain length of C 1 -C 18 , a methacrylic ester of an alkanol having a chain length of C 1 -C 18 , and an alpha-olefin having a chain length of C 2 -C 18 . 
Preferably the cheese is dried after that coating is applied.
Patent EP-2053035-B1 (EP)
Inventor: GILBEAU PATRICK
IPC: C07C29/62
Filed: 2004-11-18
Granted: 2011-03-16
Abstract: Process for producing dichloropropanol according to which glycerol is subjected to a reaction in a liquid reaction medium with a chlorinating agent comprising hydrogen chloride, wherein a continuous or periodic withdrawal of a fraction (I) comprising at least water, dichloropropanol and hydrogen chloride is carried out, wherein said fraction (I) is introduced into a distillation step, wherein a fraction (II) containing at least water and hydrogen chloride in an amount of less than 10 % by weight of hydrogen chloride and of at least 1 mg of hydrogen chloride/kg, is separated from said distillation step, and wherein said fraction (II) is recycled to the distillation step.
Patent EP-1975995-B1 (EP)
Inventor: MARION FRANCOIS
IPC: H01L23/498
Filed: 2008-03-20
Granted: 2011-06-15
Abstract: The method involves depositing a useful solder ball (6) e.g. indium, on a wettability zone (7) of an electronic component (1). Another wettability zone (8) of an electronic chip (2) is set in contact with the ball. A quantity of brazing material (11) is deposited on the component and in contact with a conductor track (4), where the material forms a sacrificial stud (10) in series, on the track, between a gold lead (5) and welding/hybridization stud. The contact surface of the brazing material is greater than that of the ball constituting the welding/hybridization stud.
Patent EP-2118156-B1 (EP)
Inventor: HERRERA TABOADA LIDCAY
IPC: C08F8/44
Filed: 2008-02-06
Granted: 2010-11-03
Abstract: The present invention relates to processes for preparing a phosphorus-containing polymer, comprising the steps of (i) copolymerizing at least (a) monoethylenically unsaturated dicarboxylic anhydrides having from 4 to 6 carbon atoms with (b) olefins of the formula CH<SUB>2</SUB>=C(R<SUP>1</SUP>)R<SUP>2</SUP> where R<SUP>1</SUP> is H or CH<SUB>3</SUB> and R<SUP>2</SUP> is H, CH<SUB>3</SUB>, C<SUB>2</SUB>H<SUB>5</SUB> or phenyl, and (c) phosphorus-containing ethene derivatives of the formula CH<SUB>2</SUB>=CHX where X is a phosphoric acid radical, a phosphonic acid radical, a phosphorous acid radical or a corresponding salt or corresponding ester; (ii) at least partly ring-opening the remaining anhydride groups. The invention further relates to phosphorus-containing polymers obtainable from this process and to processes for preventing Ba/Sr scale with the aid of the polymer.
Patent EP-2166611-B1 (EP)
Inventor: KATO RYOICHI
IPC: H01M10/052
Filed: 2008-04-18
Granted: 2013-12-25
Abstract: The present invention provides a nonaqueous electrolyte mainly comprising a nonaqueous solvent and an electrolyte dissolved therein, wherein the nonaqueous electrolyte comprises at least one compound selected from the group consisting of saturated chain hydrocarbons, saturated cyclic hydrocarbons, aromatic compounds having a halogen atom, and ethers having a fluorine atom, and further comprises a monofluorophosphate and/or a difluorophosphate.
Patent EP-2173242-B1 (EP)
Inventor: TARASSENKO LIONEL
IPC: A61B5/08
Filed: 2008-06-13
Granted: 2011-05-04
Abstract: An example method and apparatus for measuring the breathing rate from the photoplethysmogram signal (PPG) uses auto-regressive modelling of the signal. The PPG signal is windowed in overlapping windows of typically 30 seconds' length, overlapping by 25 seconds, to obtain discrete sections of the signal and each section is low-pass filtered, downsampled and detrended and then AR modelled using an all-pole auto-regressive (AR) model. The AR model allows identification of the dominant frequencies in the signal and the pole corresponding to the breathing rate is identified by considering its magnitude and the breathing rate it represents. Each 30 second window gives a breathing rate estimate and use of successive windows displaced by 5 seconds results in a breathing rate estimate every 5 seconds. The time series of breathing rate estimates can be Kalman filtered to reject measurements which have a large change in magnitude or represent a large change in breathing rate. The measurements may also be fused with measurements from another sensor.
Patent EP-2195385-B1 (EP)
Title: Composition de copolymère polycarbonate-poly(ester-éther), procédé de fabrication et objets fabriqués à partir de celle-ci
Inventor: VOLLENBERG PETER
IPC: C08L67/02
Filed: 2008-09-12
Granted: 2012-08-01
Abstract: L'invention concerne une composition comprenant de 5 à 95 % en poids d'un polycarbonate et de 5 à 95 % en poids d'un copolymère de poly(ester-éther), par rapport au poids total de la composition. Le copolymère de poly(ester-éther) comprend des unités dérivées de l'acide téréphtalique ou d'un équivalent chimique de celui-ci, des unités dérivées de butanediol ou d'un équivalent chimique de celui-ci, et 23 à 70 % en poids d'unités dérivées de poly(oxytétraméthylène)glycol ou d'un équivalent chimique de celui-ci, par rapport au poids du copolymère. La composition comprend également de 0,001 à 0,5 % en poids d'un désactiveur. La composition présente une dureté Shore D dans la plage de 45 à 75 ; et une ductilité lors de l'essai de choc Izod sur barreau à basse température d'au moins 80 % à -40 °C, mesurée selon la norme ASTM D256.
Patent EP-2207431-B1 (EP)
Title: Procédé de préparation de produits à base de thé et produits obtenus au moyen de ce procédé
Inventor: COLLIVER STEVEN PETER
IPC: A23F3/16
Filed: 2008-10-30
Granted: 2011-03-30
Abstract: L'invention concerne un procédé consistant à obtenir du thé frais riche en tiges et à exprimer un jus à partir de ce thé frais de façon à produire un résidu de tiges et un jus de thé comprenant un mélange de composés de thé.
Patent EP-2209848-B1 (EP)
Inventor: KLIESCH HOLGER
IPC: C08J7/043
Filed: 2008-11-05
Granted: 2011-09-28
Abstract: Die Erfindung betrifft eine Polyesterfolie, umfassend mindestens eine Basisschicht (B) und mindestens eine antimikrobiell wirksame Beschichtung, wobei diese antimikrobielle Beschichtung a) ein Ammoniumsilan der folgenden allgemeinen Formel (I) enthält: wobei R1 und R2 jeweils gleich oder verschieden sind und unabhängig voneinander Wasserstoff- oder C1-C8-Alkylreste sind, die geradkettig oder- im Falle der C3-C8-Alkylreste - verzweigt sein können, bevorzugt sind R1 und R2 gleich und bedeuten -CH3; in wässrigen Dispersionen bedeuten ein, zwei oder alle R1-Reste Wasserstoff; n größer als 0 und kleiner als 10 ist, bevorzugt 2 - 5 und besonders bevorzugt 3; m größer als 0 und kleiner als 30 ist, bevorzugt 6 - 25 und besonders bevorzugt 15 - 20 und ganz besonders bevorzugt 17; X' Chlorid, Sulfat oder Nitrat ist; und b) die Beschichtung eine Dicke von kleiner 1 μm, bevorzugt kleiner 0,3 μm und besonders bevorzugt kleiner 0,15 μm, aufweist.
Patent EP-2216790-B1 (EP)
Inventor: HIGUCHI TAKAYUKI
IPC: H01B1/00
Filed: 2008-11-21
Granted: 2012-07-11
Abstract: Disclosed is an electrically conductive paste which enables to reduce the level of void growth in a conducting pathway formed in a joint part produced after curing the electrically conductive paste in the implementation of an electronic component on a circuit board by using the electrically conductive paste, and which contains a reduced amount of a viscosity-adjusting/thixotropy-imparting additive. Two Sn-containing low-melting-point alloy particles having different melting points and different average particle diameters are selected as electrically conductive filler components to be used in an electrically conductive paste, and the two alloy particles are mixed at a predetermined ratio for use.
Patent EP-2112103-B1 (EP)
Inventor: BAUER HELMUTH
IPC: B65G69/18
Filed: 2009-04-03
Granted: 2011-06-08
Abstract: The method involves connecting a dosing outlet (3) of a dosing unit (1) to a receiving inlet (12) of a container (10), and opening the outlet and the inlet. A bulk product is transported from the unit into the container, where the outlet is arranged at the unit by elastic joining elements (13) to prevent transfer of forces between the outlet and inlet and between the inlet and the container. The outlet and the inlet are arranged relative to the unit and/or the container such that the elements prevent transfer of forces during transport of the product from the unit to the container. An independent claim is also included for a device for providing contamination-free transport of pourable bulk product.
Patent EP-2098905-B1 (EP)
Inventor: YAMAGUCHI MASAO
IPC: F21V5/00
Filed: 2009-03-04
Granted: 2011-01-12
Abstract: Light flux control member (5) has back face (12) provided with first recess portion (14) and ventilation grooves (19A,19B). Output light of light emitting element (4) arranged as to correspond to first recess portion (14) enters into light flux control member (5) via recess portion (14) and ventilation grooves (19A,19B), being emitted from light control emission face (6) of light flux control member (5) after inner-propagation. Refraction of incident light to second recesses portion (15) formed in ventilation grooves (19A,19B) hardly generate inner-propagation light which has travelling directions near to a direction of reference optical axis (L). This avoids emission from light control emission face (6) from providing a ring-like bright part. In addition, heat emitted from light emitting element (4) can be released at a high efficiency because a space in first recess portion (14) communicates with the outside of light flux control member (5) via the ventilation grooves (19A,19B).
Patent EP-2116524-B1 (EP)
Inventor: STRELCHENOK OLEG
IPC: A61P31/00
Filed: 2002-03-05
Granted: 2012-10-03
Abstract: This invention relates to the synthesis of sodium salts of retinoyls derivatives, capable of potentiating the efficacy of therapeutically active compounds, for example cytotoxic compounds used in the treatment of cancer. These compounds have been shown to increase the pharmacological activity of a conventional paclitaxel formulation and to make it possible to manufacture a new formulation of paclitaxel, exhibiting improved solubility, improved storage properties, and increased therapeutic efficacy as shown in the enclosed examples.
Patent EP-2259792-B1 (EP)
Inventor: DEUBZER HEDWIG ELISABETH
IPC: A61P35/00
Filed: 2009-02-04
Granted: 2011-10-05
Abstract: The present invention is concerned with the therapy of neuroblastoma and related diseases. Specifically, the present invention relates to a method for treating or preventing neuroblastoma comprising administering to a subject a therapeutically effective amount of bone morphogenetic protein 4 (BMP4). Preferably, said BMP4 is applied together with chemotherapy and/or radiation therapy.
Patent EP-2291611-B1 (EP)
Inventor: TRUM JEROEN
IPC: G01C21/32
Filed: 2009-06-24
Granted: 2018-06-06
Abstract: This invention relates to a navigation device (200) comprising a processor (210); and a store (230) containing map data, wherein the map data comprises a temporally-variable feature and the processor (210) is arranged, in a route planning process, to determine a status of the temporally-variable feature according to temporal information.
Patent EP-2334853-B1 (EP)
Inventor: KOLBE AXEL
IPC: D01F2/02
Filed: 2009-08-25
Granted: 2013-12-18
Abstract: The invention relates to cellulosic moldings having very finely distributed zinc pigments after the dry-wet extrusion method. Cellulosic moldings formed in accordance with the inventive methods, compared to unmodified cellulose fibers, have a high degree of whiteness combined with greatly increased UV light absorption and a wash-resistant bactericidal effect, while at the same time having unrestricted textile processability. The cellulosic functional moldings produced according to the invention are particularly suited for use in textiles for clothing, technical textiles, recreation, medicine, and cosmetics.
Patent EP-2323874-B1 (EP)
Inventor: KRALIK MARTIN
IPC: B60R25/0215
Filed: 2009-08-11
Granted: 2012-06-06
Abstract: The invention relates to a locking device (10) for locking a functionally essential component (11) of a vehicle with a movable locking element (13) which can assume at least two positions, specifically a locked position (Ia) in which the locking element (13) is operatively connected to the component (11) and locks the component (11), and an unlocked position (Ib) in which the locking element (13) is not operatively connected to the component (11), and an energy accumulator (15) which is mechanically operatively connected at least partially with the locking element (13) and which is charged when the locking element (13) changes from the unlocked position (Ib) into the locked position (Ia) and discharges this energy for adjusting the locking element (13) when there is a reverse change from the locked position (Ia) into the unlocked position (Ib), wherein the energy accumulator (15) is charged by means of a first activation element (17). The invention provides that a second activation element (18) is provided which, when the locking element (13) changes from the locked position (Ia) into the unlocked position (Ib), assists the energy accumulator (15) only in a special case if the locking element (13) is trapped and the energy of the energy accumulator (13) is not sufficient to move the locking element (13) out of the locked position (Ia).
Patent EP-2303251-B1 (EP)
Title: Nouvelle combinaison pour une utilisation dans le traitement de troubles inflammatoires
Inventor: RAUD JOHAN
IPC: A61P37/00
Filed: 2009-04-03
Granted: 2012-05-16
Abstract: L'invention porte sur des produits de combinaison comprenant (a) du pémirolast, ou un sel ou solvate pharmaceutiquement acceptable de celui-ci; et (b) un composé qui inhibe la formation et/ou l'action de l'angiotensine II, ou un sel ou solvate pharmaceutiquement acceptable de celui-ci. De tels produits de combinaison trouvent une utilité particulière dans l'athérosclérose et des états apparentés.
Patent EP-2328866-B1 (EP)
Inventor: MEIJER LAURENT
IPC: A61P25/00
Filed: 2009-07-21
Granted: 2012-02-29
Abstract: Indirubin derivatives of formula I   
wherein 
R represents -(A) n - R 1  or -CO-N(R 2 ,R 3 ) with 
¢ A being C1-C5 alkylene group, optionally substituted by one or several A 1  radical, A 1  being an halogen Br, OH, OR 4  or NH 2 , R 4  being C1-C5 alkyl; 
¢ R 1  being halogen, OH, N(R 2 , R 3 ); R 2  and R 3 , identical or different, being C1-C5 alkyl, optionally substituted by A 1  such as above defined, or R 2  and R 3  are part of a cycle with 5 or 6 elements optionally comprising another heteroatom such as O or N; 
¢ n = 1-5.  It also relates to the biological application thereof.