baber/WOPTO huggingface dataset:
Patent WO-9835684-A2 (WO)
Title: Methodes de detection d'un virus semblable a l'herpesvirus associe au sarcome de kaposi
Inventor: BERENSON JAMES R
IPC: A61K39/245
Filed: 1998-02-12
Abstract: La présente invention concerne des méthodes de détection et d'identification de séquences d'acides nucléiques ou de protéines spécifiques à un virus semblable à l'herpèsvirus associé au sarcome de Kaposi (KSHV) dans des échantillons biologiques prélevés sur des patients chez qui on a diagnostiqué un myélome multiple (MM) ou une gammapathie monoclonale de signification non déterminée (MGUS). On détecte les séquences d'acide nucléique spécifiques de KHSV chez ces patients par amplification en chaîne par polymérase (PCR) ou amplification en chaîne par polymérase à transcription inverse (RT-PCR) pour amplifier des séquences spécifiquement virales endogènes des tissus/cellules de ces patients. La présente invention concerne également plusieurs méthodes de traitement prophylactique et/ou thérapeutique de ces patients atteints de MM ou MGUS. Un traitement potentiel selon la présente invention comprend, de manière non exhaustive: (1) l'utilisation d'acides nucléiques inhibiteurs (INAs), tels que des oligonucléotides 'antisens' pour inhiber plusieurs processus viraux (comme par exemple une réplication de l'ADN, une transcription d'ARN messager et/ou une traduction de protéine); (2) l'utilisation d'anticorps polyclonaux ou monoclonaux spécifiquement viraux, ou de leurs fragments ou dérivés biologiquement actifs, dont la liaison peut servir à inhiber une infection virale initiale, des processus réplicatifs/de synthèse protéique, ou à 'fournir' des agents antiviraux conjugués à une partie de l'immunoglobuline; (3) l'utilisation d'agents chimiothérapeutiques antiviraux systémiques inhibant une infection virale ou des processus réplicatifs/de synthèse protéique; et/ou (4) l'utilisation d'un vaccin spécifique de KHSV inoculé à des individus pour éliciter une réponse immunitaire prophylactique ou thérapeutique par utilisation de séquences d'acides nucléiques ou de protéines recombinées spécifiques de KHSV pour éliciter une (des) réponse(s) immunitaire(s).
Patent WO-9953085-A2 (WO)
Title: Regulation selective de la production d'adenovirus
Inventor: HEARING PATRICK
IPC: C12N5/10
Filed: 1999-04-15
Abstract: La présente invention concerne des vecteurs d'adénovirus et leur utilisation dans des systèmes d'apport d'ADN. Ces vecteurs ont été conçus pour présenter une capacité améliorée à porter un ADN étranger et un potentiel minimisé de production de virus de réplication. Ces vecteurs contiennent par ailleurs une ou plusieurs copies d'une séquence d'encapsidation minimale, afin de diriger l'encapsidation virale. Ces vecteurs contiennent éventuellement un ou plusieurs sites de liaison de répresseurs, de sorte que la production de virions peut être sélectivement inhibée. L'invention concerne également des systèmes de répression spécifiques, comprenant les répresseurs COUP-TF et lac. L'invention concerne enfin un complexe cellulaire, ci-après dénommé complexe P, fonctionnant de manière positive dans l'encapsidation et la production virales.
Patent AT-512101-A2 (AT)
Title: Messeinrichtung zur glukosemessung
IPC: A61B5/00
Filed: 2011-10-31
Abstract: Die Erfindung betrifft eine Messeinrichtung zur Glukosemessung, umfassend einen Glukosesensor (1) zur Bestimmung des Glukosegehalts in einer Lösung oder Flüssigkeit, insbesondere in Blut, sowie zur Wiedergabe des gemessenen Glukosegehalts in Form eines elektrischen Signals mit codiert dargestellten Messdaten, eine NFC-Antenne (2), eine der NFC-Antenne (2) nachgeschaltete Energieentnahmeeinheit (3), die die NFC-Antenne (2) derart ansteuert, dass die NFC-Antenne (2) bei Vorliegen von elektromagnetischen Wellen in einem vorgegebenen Frequenzbereich Energie aus dem die NFC-Antenne (2) umgebenden Feld entnimmt, und wobei die NFC-Antenne (2) dem Glukosesensor (1) vorgeschaltet ist und diesen mit elektrischer Energie versorgt sowie eine Kommunikationseinheit (4), die von der Energieentnahmeeinheit (3) mit Energie versorgt ist, wobei der Kommunikationseinheit (4) die vom Glukosesensor (1) ermittelten Messdaten zugeführt sind und die Kommunikationseinheit (4) der NFC-Antenne (2) ein die Messdaten enthaltendes Signal aufprägt.
Patent CH-699414-A2 (CH)
Title: Ground-level light signaling device, particularly for rail-bound transport routes, has light source and optical system for signal aspect visualization in far area and near area
Inventor: ECKL ROLF
IPC: B61L5/18
Filed: 2009-08-06
Abstract: The ground-level light signaling device (LS) has a light source and an optical system for signal aspect visualization in a far area (FB) and a near area (NB). The optical system has a control element in an aperture segment of the light flow for deflection of a partial light flow in the near area. A light outlet disk is provided, which has a gray filter for phantom light reduction.
Patent CH-699314-A2 (CH)
Title: Kabelführung an einem Tisch.
Inventor: BRAEUNING EGON
IPC: A47B21/06
Filed: 2008-08-15
Abstract: Die Kabelführung an einem Tisch (1), welcher eine von einem Untergestell (10, 11, 12) getragene Tischplatte (13) aufweist, die eine Tischplattenoberseite (131) als Arbeitsfläche und eine Tischplattenunterseite (132) besitzt, umfasst einen Steckdosenblock (2), an den Elektrokabel (9) für die Stromversorgung und/oder Informationstechnik herangeführt sind und der Anschlüsse (20) zum Einstecken von Elektrokabeln (9) für die Stromentnahme und/oder Verbindung mit Geräten der Informationstechnik hat. Am Steckdosenblock (2) sind Andockmittel (25, 28, 29; 7, 74) angeordnet, die ein lösbares Anhängen des Steckdosenblocks (2) am Untergestell (10, 11, 12) oder an einem Basisteil (4) erlauben, welches benachbart zu einer in der Tischplatte (13) vorgesehenen Ausnehmung (133) angeordnet ist. Bei einer ersten Ausführungsform der Kabelführung umfassen die Andockmittel (25, 28, 29) für den Steckdosenblock (2) einen Halter (25) zur Aufnahme des Steckdosenblocks (2) und Befestigungselemente (28, 29) zur lösbaren Verbindung des Halters (25) mit dem Untergestell (10, 11, 12). Hierbei ist der Halter (25) mit Rastorganen (251) versehen, die an Komplementärkonturen am Steckdosenblock (2) angreifen, wodurch der Halter (25) und der Steckdosenblock (2) lösbar miteinander verbunden sind. Bei einer zweiten Ausführungsform der Kabelführung umfassen die Andockmittel (7, 74) für den Steckdosenblock (2) mit diesem verbundene Lager (7) und daran angeordnete Befestigungselemente (74, 76). Hierbei ist das Basisteil (4) als ein die Ausnehmung (133) an der Tischplattenunterseite (132) umrandender Rahmen (4) gestaltet, und das Basisteil (4) besitzt Gegenkonturen (43), die mit den Befestigungselementen (74, 76) der Lager (7) zusammenwirken.
Patent CH-699574-A2 (CH)
Title: Mobile diesel generator for use in e.g. road traffic to supply electrical energy to tank container, has diesel tank installed in container, where container is transported as permanent International Organization for Standardization container
Inventor: SAABEL IRMHILD
IPC: B61C5/00
Filed: 2008-09-24
Abstract: The generator has a diesel tank installed in a container. The container is transported as a permanent International Organization for Standardizationcontainer. The diesel tank is connected with the diesel generator. Container wagons are equipped with electrical lines and connections, so that the wagons comprise an electrical line network. The diesel generator is provided in the container wagons, where the generator is connected to the electrical line network. An independent claim is also included for a train comprising a wagon series consisting of container wagons with a diesel generator.
Patent CH-711733-A2 (CH)
Title: Trainingsvorrichtung für chirurgische Eingriffe, insbesondere für offene chirurgische und interventionelle vaskuläre Eingriffe.
Inventor: Anton Meile
IPC: G09B23/28
Filed: 2015-11-06
Abstract: Die Erfindung bezieht sich auf eine Trainingsvorrichtung (20) für chirurgische Eingriffe, insbesondere für offene chirurgische und interventionelle vaskuläre Eingriffe, welche ein Gehäuse (1), eine Versorgungseinheit für Flüssigkeit mit einer elektrisch betreibbaren Tauchpumpe (11) und Flüssigkeitsleitungen, eine elektrische Energieversorgung (12) und eine Plattform (9), auf der ein Präparat fixierbar ist, umfasst. Das Gehäuse (1) weist wenigstens zwei voneinander getrennte Kammern (6, 7, 8) für die Versorgungseinheit für die Flüssigkeit, die Pumpe (11) und die Flüssigkeitsleitungen, für die Energieversorgung (12), für die Instrumente und Hilfseinrichtungen zur chirurgischen Bearbeitung des Präparats und optional für das Präparat auf.
Patent CO-6270255-A2 (CO)
Title: Proceso e intermediarios para preparar inhibidores de integrasas
Inventor: DOWDY ERIC D
IPC: C07C41/30
Filed: 2010-04-05
Abstract: La invencion provee procesos sintéticos e intermediarios sintéticos que se pueden utilizar para preparar compuestos de 4-oxoquinolona que tienen propiedades ·tiles de inhibicion de integrasas. 1.- Un método para preparar un compuesto de formula 10 o una sal del mismo, en el que un compuesto de formula 4 o una sal del mismo es preparado y convertido en un compuesto de formula 10, caracterizado porque el compuesto de formula 4 es preparado a partir de un compuesto de formula 15 o una sal del mismo, mediante los pasos de reemplazar el atomo de bromo con un grupo carboxilo, y reemplazar el grupo hidroxilo con un atomo de hidrogeno. 2.- Un método de la reivindicacion 1, en donde el compuesto de formula 4 o una sal del mismo se prepara mediante metalacion del compuesto de formula 15 o una sal del mismo y tratandolo con dioxido de carbono para dar el compuesto de formula 3: o una sal del mismo, y convirtiendo el compuesto de formula 3 para dar el compuesto de formula 4.
Patent CO-6321192-A2 (CO)
Title: Moduladores de diamino-piridina pirimidina y piridazina del receptor h4 de histamina
Inventor: CAI HUI
IPC: A01N43/58
Filed: 2010-12-13
Abstract: Compuestos de diamino-piridina, pirimidina y piridazina que se pueden usar como moduladores del receptor H4, y en composiciones farmacéuticas y métodos para el tratamiento de estados de enfermedad, trastornos, y afecciones mediadas por la actividad del receptor H4, tales como alergia, asma, enfermedades autoinmunes, y prurito.
Patent CO-6761401-A2 (CO)
Title: Dispositivo de preparación para crear una bebida de café y método para crear una bebida de café por medio de un dispositivo de preparación
Inventor: REYHANLOO SHAHRYAR
IPC: A47J31/46
Filed: 2013-07-15
Abstract: El dispositivo de preparación (10) para crear una bebida de café tiene una unidad de preparación (11) que tiene una cámara de preparación (12) para preparar café, una unidad de crema (21) para crear una crema que tiene una cámara de crema (200) conectada a la cámara de preparación (11) por medio de un pasaje de café 214) y que tiene un pistón de válvula (201) para abrir y/o cerrar el pasaje de café (214), cuyo pistón de válvula se puede mover en la cámara de crema (200) con relación al pasaje de café (214), y una abertura de salida (31) para bebida de café particular, en donde la unidad de crema (21) se conecta a la abertura de salida (31) por medio de un conducto de salida (30) de tal manera que, con el fin de crear la bebida de café particular, el café preparado en la unidad de preparación (11) durante un proceso de preparación pueda fluir a través del pasaje de café (214) y la cámara de crema y alcanza la abertura de salida (31) . El pistón de válvula (201) se puede mover de tal manera que el pistón de válvula se pueda poner en una pluralidad de diferentes posiciones de movimiento específicas con relación al pasaje de café (214), en donde diferentes procesos de preparación consecutivos para crear diferentes bebidas de café se pueden llevar a cabo de tal manera que, para uno de los procesos de preparación particulares, el pistón de válvula (201) asume una posición de movimiento específica diferente de la posición de movimiento específica para un proceso de preparación diferente, y en donde la unidad de crema (21) se diseña de tal manera que el café preparado durante el proceso de preparación particular se pueda hacer girar mediante intensidad diferente dependiendo de la posición de movimiento específica particular del pistón de válvula (201).
Patent EP-1026710-A2 (EP)
Inventor: BOGNER ALBERT DIPL-ING
IPC: H01H1/42
Filed: 2000-01-26
Abstract: The switch has a contact blade (1), a fixed contact and an arc-quenching device. The contact blade has a contact surface (8) is formed by a contact head (10) which is considerably thicker than a shaft (7). The contact head includes a tip (11) made of a material that is resistant to high temperatures as it is subjected to heat due to arcing when switching.
Patent EP-1028098-A2 (EP)
Inventor: HANZAWA SHIGERU
IPC: C23C2/00
Filed: 2000-02-08
Abstract: Provided are SiC-C/C composite materials which have such
characteristics as a suitable kinetic coefficient of friction,
a corrosion resistance in strongly oxidizing and corrosive
environment, a creep resistance, and a spalling resistance, a
high hardness, and are hardly oxidized or abraded even when
exposed to high temperatures with keeping the excellent impact
resistance and light weight of the C/C composites. Furthermore,
molten metal pumps are provided from which components do not
dissolve into the molten metal even when used in molten metal
and have sufficient thermal impact resistance and oxidation
resistance. 
     The SiC-C/C composite materials can be produced by
a method comprising a step of heating a C/C composite and
metallic silicon at high temperatures under reduced pressure
with flowing an inert gas to grow silicon carbide and
simultaneously filling metallic silicon into the remaining
pores, a step of increasing the furnace inner pressure to about
1 atm. with or without cooling the furnace and further raising
the furnace inner temperature to diffuse the produced silicon
carbide or metallic silicon used for filling the pores into the
C/C composite comprising carbon fibers and carbon component
other than the carbon fibers from the matrix to react with these
carbons, and at least the portions of the molten metal pumps
contacting with molten metal are made of the SiC-C/C composite
materials.
Patent EP-1046642-A2 (EP)
Inventor: BINGEL CARSTEN DR
IPC: C07F7/08
Filed: 2000-04-17
Abstract: Processes for the production silyl bridged fluorenyl-cyclopentadienyl-metallocene compounds uses a mixture of an aromatic or aliphatic hydrocarbon and an alpha,beta-dialkoxy-alkane or aromatic compound. A process for the production of compounds of formula (1) comprises: (A) deprotonation of a compound of formula (2) with a base, (B) reaction of the deprotonated compound with a compound of formula (3) to form a compound of formula (4), (C) reaction of the compound of formula (4) with M<+>Cp<-> to form a compound of formula (5) and (D) reaction of the compound of formula (5) with a base and addition of LCl4. R<1>R<2>SiCl2 (3) R<1>, R<2> = 1-20 C hydrocarbon; R<3>-R<10> = H, halogen or 1-20C hydrocarbon; R<11>-R<14> = H or 1-20C hydrocarbon; L = zirconium, hafnium or titanium; M = Li, Na, K, MgCl or MgBr; and Cp = cyclopentadienyl,. optionally substituted Step (A) is carried out in a mixture of an aromatic and/or aliphatic hydrocarbon and an  alpha , beta -dialkoxy-alkane or  alpha , beta -dialkoxyaromatic. An alkane is added after the deprotonation step and prior to step (B). Step (D) is carried out an aromatic and/or aliphatic hydrocarbon and a polar, aprotic solvent, with the exception of diethylether.
Patent EP-1055808-A2 (EP)
Inventor: AKAMATSU SHUNJI
IPC: G01N27/409
Filed: 2000-04-13
Abstract: The invention positions an exhaust gas sensor in such a manner that a protective
cover is not required, collisions and water bursts due to flying stones are avoided as
much as possible, where maintenance work is straightforward, and where available
space is effectively utilized. 
     To achieve this, an exhaust gas sensor 29 is fitted to an upper side wall of an
exhaust pipe 26 at a position forward from a right projection 14a of a crank case 14
and facing out from a right side surface 15a of a cylinder block 15.
Patent EP-1081355-A2 (EP)
Inventor: ZAREMBA DIETER
IPC: F02B67/00
Filed: 2000-08-03
Abstract: The support (7) is connected to a casing (6), e.g. the crankcase of the engine and holds several additional units. The support is formed to guide cooling fluid from a cylinder casing (4,5) to a cooler for the cooling fluid. Sections of the support preferably run between the cylinder casings and have connection sockets (10,11) for pipelines formed as inputs (14,15) for the cooling fluid.
Patent EP-1094107-A2 (EP)
Inventor: NAGASE KAZUO
IPC: C12N15/09
Filed: 2000-10-10
Abstract: A microorganism belonging to the genus Methylobacillus
having aspartokinase activity and/or dihydrodipicolinate
synthase activity wherein the aspatokinase and the
dihydrodipicolinate syntase activity are substantially
insensitive to feedback inhibition by L-lysine.
Patent EP-1095657-A2 (EP)
Inventor: COHEN IRUN R
IPC: A61K31/70
Filed: 1993-11-09
Abstract: Substances comprising a N-sulfated or N-acetylated or non-sulfated N-acetylated
4-deoxy-4-en-iduronoglucosamine in substantially purified form,
including compositions containing same and their uses are disclosed for the
regulation of cytokine activity in a host. For instance, the secretion of Tumor
Necrosis Factor Alpha (TNF-α) can be either inhibited or augmented selectively by
administration to the host of effective amounts of substances or their compositions
comprising specific oligosaccharides in substantially purified form. Thus, the present
invention also relates to pharmaceutical compositions and their use for the prevention
and/or treatment of pathological processes involving the induction of active cytokine
secretion, such as TNF-α. The invention also relates to the initiation of a desirable
immune system-related response by the host to the presence of activators, including
pathogens. The substances and pharmaceutical compositions of the present invention
may be administered daily, at very low effective doses, typically below 0.1 mg/kg
human, or at intervals of up to about 5-8 days, preferably once a week.
Patent EP-1120994-A2 (EP)
Inventor: BACHMANN WOLFGANG DR
IPC: H04R7/06
Filed: 2000-11-16
Abstract: The flat loudspeaker arrangement comprises several loudspeakers arranged seamlessly. Each loudspeaker comprising a driver (18) for oscillation generation, sound disk (13) and support stand (14), works on multi-resonance flexible shaft principle.
Patent EP-1107367-A2 (EP)
Inventor: CHEN WENZONG
IPC: H01R12/71
Filed: 2000-11-29
Abstract: A system is disclosed for mounting a connecting device (36) to a
substrate (32) with relative floating movement therebetween. The system includes a
connector housing (46). A fastening nut (60) is captured by the housing with relative
floating movement therebetween. The nut includes a shank portion (60a) extending
toward the substrate through an opening (66b) in a wall portion (67) of the housing. The
shank portion (60a) of the nut (60) is longer than the thickness (D) of the wall portion
(67) of the housing. A fastener (62) is engaged with the substrate (32) and is operatively
associated with the fastening nut (60) for tightening the nut against the substrate, leaving
the connector housing (46) with floating movement relative to the substrate (32).
Patent EP-1123753-A2 (EP)
Inventor: MACDOUGALL JAMES EDWARD
IPC: C08L53/00
Filed: 2000-12-06
Abstract: A process provides a ceramic film, such as a mesoporous silica film, on a
substrate, such as a silicon wafer. The process includes preparing a film-forming fluid
containing a ceramic precursor, a catalyst, a surfactant and a solvent, depositing the
film-forming fluid on the substrate, and removing the solvent from the film-forming fluid
on the substrate to produce the ceramic film on the substrate. The ceramic film has a
dielectric constant below 2.3, a halide content of less than 1 ppm and a metal content of
less than 500 ppm, making it useful for current and future microelectronics applications.
Patent EP-1084687-A2 (EP)
Inventor: SOSALLA PAULA MARY
IPC: A61F5/44
Filed: 1995-07-14
Abstract: A distinctive absorbent article has a front waistband portion
(12), a back waistband portion (14) and an intermediate portion
(6) which interconnects the front and back waistband portions.
The article comprises a backsheet layer (30), and an absorbent
retention portion (48) superposed on the backsheet layer. A
liquid permeable topsheet layer (28) is superposed on the
retention portion and connected to sandwich the retention
portion between the topsheet and the backsheet layers. At least
one elasticized side panel is connected to a lateral end region
of said back waistband portion of said article. Said side panel
is constructed for interconnecting with said article about a
wearer's body to thereby form an assembled bridge flap.
Patent EP-1031423-A2 (EP)
Inventor: CHATTERJEE DILIP K
IPC: B41J2/16
Filed: 2000-02-11
Abstract: A method for injection molding fine particulate ceramic
ferroelectric materials to form an article such as ink jet printhead includes the
steps of spray drying fine particulate ceramic ferroelectric material to form
agglomerate material; mixing the spray dried fine particulate ceramic ferroelectric
agglomerate material with a binder system including materials selected from the
group consisting of wax having wax components of different molecular weight,
magnesium-X silicate, agaroid gel forming material, and agaroid gel forming
material mixed with magnesium-X silicate to form a compounded material;
injecting the compounded material at a selected pressure into a mold to form a
green article; debinding or drying the green article; sintering the debinded or dried
green article to form the final molded article; poling the final molded article to
align the electrical dipoles within the piezoelectric material; forming a coating of
conductive material over the top and bottom surfaces of the final molded article
and then cutting grooves through conductive coating into the top surface in the
valleys of the final molded article to form a channel member; and providing an
orifice plate over top surface of the channel member and a substrate over the
bottom surface of the channel member.
Patent EP-1091243-A2 (EP)
Inventor: SOLOMON JEFFREY A
IPC: G03B17/04
Filed: 2000-09-25
Abstract: A camera frame assembly or other apparatus has a flash unit having
a self-oscillating charging circuit. The camera frame assembly is used with a
filmstrip and a battery. The camera frame assembly has a film scrolling chamber
and a battery compartment joined to the film scrolling chamber. The flash unit is
joined to the chamber, in the camera frame assembly. The flash unit has near and
far battery contacts coupled to the circuit. The contacts define an active battery
station within the compartment configured to receive the battery in electrical
series with the circuit via the contacts. At least one of the battery contacts is
biased inwardly to restrain the battery within the active battery station. A battery
grip is disposed in the compartment exterior to the near battery contact. The
battery grip defines a standby battery station that is spaced from the near contact
sufficiently to isolate the standby battery station from the circuit. At least one of
the far battery contact and the battery grip is biased inwardly to restrain the battery
within the standby battery station.
Patent EP-1035514-A2 (EP)
Inventor: GAWLER DAVID ANTHONY
IPC: G07B17/00
Filed: 2000-02-14
Abstract: A method of accounting for postage charges in respect of
batches of mail items is disclosed. The method includes
storing an accumulated aggregate value (41) of postage
dispensed in applying postage charges to mail items and
storing an accumulated pending value (42) of postage
dispensed in applying postage charges to mail items of a
batch of mail items which has not been completed. In
response to completion of the batch of mail items, the
accumulated pending value (42) is decremented by a value
of postage relating to the completed batch of mail items.