baber/WOPTO huggingface dataset:
Patent CA-2483253-A1 (CA)
Inventor: TSUCHIMORI NOBORU
IPC: A61K31/445
Filed: 2003-04-23
Abstract: It is intended to provide preventives/remedies for graft versus host disease and/or rejection in organ or bone marrow transplantation, rheumatoid arthritis, autoimmune diseases, allergic diseases, ischemic cerebral cell injury, myocardial infarction, chronic nephritis and arteriosclerosis. The above object can be achieved by preventives/remedies for graft versus host disease and/or rejection in organ or bone marrow transplantation, rheumatoid arthritis, autoimmune diseases, allergic diseases, ischemic cerebral cell injury, myocardial infarction, chronic nephritis and arteriosclerosis characterized by containing a specific compound having CCR (CC chemokine receptor) antagonism.
Patent CA-2483257-A1 (CA)
Inventor: EBERHARDT CAROL E
IPC: A61F2/24
Filed: 2003-03-13
Abstract: L'invention concerne un procédé et un appareil destiné à limiter l'extension longitudinale au cours de la fixation d'une racine aortique prélevée comprenant des valvules et le produit qu'elle produit. L'appareil comprend un bouchon d'amenée introduit dans la section d'amenée de la racine aortique et un tube ouvert ou une canule s'étendant à travers les valvules vers un bouchon de sortie introduit dans la section de sortie de la racine aortique. Les ouvertures ménagées dans le tube sont situées sur les deux côtés de la valvule et le tube est couplé à une entrée de fluide de préférence situé sur le bouchon de sortie. Le bouchon de sortie peut être coulissé par rapport au tube et comprend un mécanisme de couplage notamment une vis sans tête destinée à fixer la position du bouchon de sortie par rapport au tube et au bouchon d'amenée. Après assemblage de la racine aortique à l'appareil, l'entrée de fluide est couplée à une source possédant une pression définie et la racine est gonflée. Le bouchon de sortie est ensuite fixé par rapport au tube en vue de définir une élongation maximale de la racine, puis un fixateur est ensuite introduit dans la racine via le tube muni d'ouvertures.
Patent CA-2484362-A1 (CA)
Title: Interactive multi-sensory reading system electronic teaching/learning device
Inventor: ERNST STEPHEN M
IPC: G09B5/00
Filed: 2003-05-30
Abstract: An electronic learning/teaching device (100) operates with and without a printed sheet element (20) having an arrangement of selectable content by means of a user responsive sensor array (142) beneath a surface (130) configured to receive the element. The sensor array is formed by cross-points of two sets of crossing conductive lines (246, 248), one set being driven sequentially with a radio frequency square wave and the other set being sampled sequentially though a high impedance amplifier connection with an asynchronous detection circuit. Where more than one cross-point location is user activated, algorithms (Fig. 12) are used to identify one cross-point sensor location as the user activated selection.
Patent CA-2486771-A1 (CA)
Inventor: PROFFITT SONDRA DENICE
IPC: F24C7/02
Filed: 2004-11-04
Abstract: A microwave delivery system for a cooking appliance includes a toroidal waveguide, a launching zone and a waveguide cover. The launching zone includes opposing top, bottom and side walls that form a pathway for a microwave energy field to travel from a magnetron through the waveguide and into a cooking chamber. In accordance with one aspect of the overall invention, the bottom wall of the launching zone is aligned with a bottom surface of the waveguide to establish a direct conducting surface for the microwave energy field. The waveguide cover shields a hollow interior portion of the waveguide from cooking byproducts generated in the cooking chamber during a cooking process.      The waveguide cover is preferably constituted by a metallic conductor having a finish that enhances the microwave energy field distribution in the cooking chamber.
Patent CA-2488302-A1 (CA)
Inventor: HACHE JEAN-MICHEL
IPC: E21B47/06
Filed: 2004-11-23
Abstract: An apparatus and method useful for acquiring information from a subsurface formation penetrated by a wellbore contemplate the use of a tubular body adapted for connection within a drill string disposed in the wellbore. The tubular body is equipped with one or more protuberances (e.g., ribs) defining an expanded axial portion. A probe is carried by the tubular body at or near a first location within the expanded axial portion of the body where the cross-sectional area of the expanded axial portion is a minimum. The probe is movable between retracted and extended positions. In another aspect, the inventive apparatus may further include a cover releasably-secured about the probe for protecting the probe while drilling. In a further aspect, the inventive apparatus may include a shearable backup support carried by the tubular body azimuthally opposite the probe permitting release of the apparatus from the wellbore in the event of a failure. In yet another aspect, the probe is at least partially carried within a debris-clearing channel formed in a protruding portion of the tubular body to promote fee movement of the probe within the wellbore.
Patent CA-2491864-A1 (CA)
Title: Super humanized antibodies
Inventor: FOOTE JEFFERSON
IPC: G06F19/00
Filed: 2002-07-12
Abstract: Disclosed herein are methods for humanizing antibodies based on selecting variable region framework sequences from human antibody genes by comparing canonical CDR structure types for CDR sequences of the variable region of a non-human antibody to canonical CDR structure types for corresponding CDRs from a library of human antibody sequences, preferably germline antibody gen e segments. Human antibody variable regions having similar canonical CDR structure types to the non-human CDRs form a subset of member human antibody sequences from which to select human framework sequences. The subset members may be further ranked by amino acid similarity between the human and the non - human CDR sequences. Top ranking human sequences are selected to provide the framework sequences for constructing a chimeric antibody that functionally replaces human CDR sequences with the non- human CDR counterparts using the selected subset member human frameworks, thereby providing a humanized antibody of high affinity and low immunogenicity without need for comparing framework sequences between the non-human and human antibodies. Chimeric antibodies made according to the method are also disclosed.
Patent CA-2493344-A1 (CA)
Title: Titanium-zirconium catalyst compositions and use thereof
Inventor: ENG JOHN H
IPC: B01J31/02
Filed: 2003-07-23
Abstract: A catalyst composition prepared from (a) titanium tetrahydrocarbyloxide, (b) zirconium tetrahydrocarbyloxide, and (c) tetraalkyl ammonium hydroxide, wherein the molar ratio of Zr:Ti is from about 0.02:1 to about 5:1 and the molar ratio of TAAH:(Ti+Zr) is from about 0.05:1 to about 2:1.
Patent CA-2493805-A1 (CA)
Title: Interconnection system
Inventor: BENHAM JOHN E
IPC: H01R13/646
Filed: 2003-07-23
Abstract: An interconnection system includes spacers (5010,5040), arranged adjacent each other in a row, the spacers having printed circuit board (5020) disposed therebetween. Electrically conductive contacts are disposed within cells in a pair of interposers (5080, 5081) so as to have one end making electrical contact with one of the printed circuit boards and another end extending through its respective cell in its interposer.
Patent CA-2494506-A1 (CA)
Title: Development of muscle mass in a mammal
Inventor: SUMMERS DAVID P
IPC: A61K31/4439
Filed: 2003-08-02
Abstract: In a method of developing muscle mass in a mammal, nicotine or nicotine acetylcholine receptor agonist (nAChR) is administered in combination with exercise to stimulate, recruit and mobilize muscle cells to a specific muscle mass.
Patent CA-2494538-A1 (CA)
Inventor: WALLACE BRUCE
IPC: C12Q1/68
Filed: 2003-07-25
Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms usi ng a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
Patent CA-2496079-A1 (CA)
Inventor: MONTAGNINO JOE C
IPC: B29L7/00
Filed: 2005-02-04
Abstract: A method of making a composite microporous membrane includes the steps of: coating a nonporous precursor film with a polymer composition, and then stretching the coated nonporous precursor.      Stretching includes a first stretching conducted at a first temperature and a first stretching rate and a second stretching conducted at a second temperature and a second stretching rate.    The first stretching rate and the second stretching rate are different.
Patent CA-2497673-A1 (CA)
Inventor: CARLSEN JENS
IPC: F16B15/08
Filed: 2003-10-02
Abstract: Cette invention se rapporte à un outil servant à la fabrication de clous à tête désaxée, un tel clou comprenant une tige et une tête, dont le centre est désaxé par rapport au centre de la tige. Cet outil fait partie d'un ensemble d'au moins deux outils agissant conjointement sur une ébauche de clou. Cet outil comprend un côté avant pourvu d'une ouverture réceptrice et un côté supérieur à utiliser lors de la formation de la tête. Cette ouverture réceptrice a une forme conçue pour produire une impression dans l'ébauche et pour fixer l'ébauche pendant la formation de la tête sur l'ébauche. Cette invention concerne en outre l'utilisation de cet outil. De tels clous avec têtes désaxées sont utilisés dans des cloueuses automatiques, dans lesquelles une bande de clous est utilisée pour des éjections multiples de clous, avant le rechargement de la cloueuse avec une nouvelle bande de clous. Les aspects nouveaux et inventifs de cet outil selon cette invention consistent en ce que l'ouverture réceptrice comporte une section saillante près du côté supérieur destinée à former dans la tige du clou une impression, placée adjacente à la tête et essentiellement à un côté, qui est opposé à la direction dans laquelle la tête est désaxée, et en ce que cette section saillante comporte au moins une surface essentiellement plate ou convexe destinée à former au moins une section essentiellement plate ou concave sur le clou, cette section plate ou convexe étant située essentiellement parallèle à l'axe longitudinal de l'ouverture réceptrice. Ainsi, on confère au clou une grande résistance dans la zone de transition entre la tige et la tête.
Patent CA-2498051-A1 (CA)
Inventor: BARFACKER LARS
IPC: C07D417/04
Filed: 2003-08-28
Abstract: L'invention concerne des nouveaux dérivés hétérocycliques, des procédés de préparation de ceux-ci et l'utilisation desdits dérivés dans des médicaments, notamment pour le traitement de maladies obstructives respiratoires, du syndrome coronarien aigu, de l'infarctus aigu du myocarde et du développement d'une insuffisance cardiaque.
Patent CA-2498064-A1 (CA)
Inventor: GIACOMELLO MAURO ANTONIO
IPC: G06Q20/10
Filed: 2003-08-13
Abstract: A data processing system comprises at least one resource manager (RM) for managing changes to respective system resources in accordance to a commit/backout protocol, and a resource manager coordinator (RMC) for coordinating the commit/backout activities of the at least one resource manager. A process resource manager (ERM) is provided, coordinated by the resource manager coordinator according to the commit/backout protocol, for managing the execution of non-~compliant processes not complying with the commit/backout protocol. The process resource manager automatically determines, upon receipt of a backout request, a sequence of compensation actions to be performed to backout actions performed during the execution of the secondary non~-compliant processes, and managing the execution of said compensation actions.
Patent CA-2498862-A1 (CA)
Title: Apparatus and process for mining of minerals
Inventor: POTTS ALAN
IPC: E21C41/24
Filed: 2002-12-20
Abstract: Apparatus for transporting mineral from a point of mining to a remote location, the apparatus including a mobile mineral breaker rig (MBR) having a mineral outlet, the rig including a fluid inlet pipe for receiving conveying fluid, a mineral inlet for introducing mineral from said mineral outlet into said fluid pipe and a fluid outlet pipe for conveying said fluid mixed with mineral received from said mineral outlet, an extensible pipeline assembly (EPA) connected at one end to said inlet and outlet pipes and being adapted for connection at its opposite end to one end of a static pipeline communicating with said remote location, said extensible pipeline assembly being expandable to enable said mobile rig to move away from said one end of the static pipeline whilst maintaining fluid communication therewith, said extensible pipeline assembly comprising a series of elongate pipe assemblies (90a, 90b, 90c) which are articulated at adjacent ends to one another in a zig-zag manner via an articulated joint, each elongate pipe assembly including two lengths of pipe which are arranged side-by-side and secured together such that one length of pipe defines an upper pipe and the other length of pipe defines a lower pipe, the articulated joint between each end of adjacent elongate pipe assemblies including an upper rotary joint (107) which connects adjacent ends of the upper pipes of adjacent pipe assemblies and a lower rotary joint (106) which connects adjacent ends of the lower pipes of adjacent pipe assemblies, the axis of rotation of the upper and lower rotary joints of each articulated joint being co-axial.
Patent CA-2501128-A1 (CA)
Inventor: POOLE ROBERT N
IPC: G11B23/03
Filed: 2003-09-16
Abstract: La présente invention concerne un couvercle protecteur (10) conçu pour protéger la face de lecture d'un disque optique (40), lequel couvercle comporte un cadre circonférentiel (14) conçu pour recevoir et entrer en contact avec le disque optique (40) et un écran protecteur (12). Le cadre (14) comprend une paroi terminale continue (24), une base annulaire (20) s'étendant radialement vers l'intérieur à partir d'un bord inférieur (22) de la paroi terminale (24), et une pluralité de languettes (26) espacées les unes des autres et s'étendant radialement vers l'intérieur à partir d'un bord supérieur (28) de la paroi terminale (24) pour entrer en contact avec une surface supérieure (45) d'un disque optique (40). L'écran protecteur (12) est transparent et possède un bord interne (17) définissant une ouverture centrale (18), un bord externe (16) et une surface annulaire généralement plane s'étendant entre le bord externe (16) et le bord interne (17). L'écran protecteur (12) est porté par la base annulaire (20) conçu pour recevoir et recouvrir la face de lecture (46) du disque optique (40).
Patent CA-2501534-A1 (CA)
Title: Dihydropyridine compounds having simultaneous ability to block l-type calcium channels and to inhibit phosphodiesterase type 3 activity
Inventor: HAMILTON GREGORY S
IPC: C07D487/04
Filed: 2003-10-07
Abstract: The present invention provides compounds that possess inhibitory activity against PDE-3 and L-type calcium channels. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine.
Patent CA-2502953-A1 (CA)
Title: Wood cement board and method for the manufacturing thereof
Inventor: ENDO KOICHIRO
IPC: C04B28/00
Filed: 2005-03-31
Abstract: The object of the present invention is to provide a light weight wood cement board having high strength and sufficient toughness. To attain the object, the present invention provides a wood cement board made of a cured raw material mixture of cementitious inorganic powder (C), a material containing silica (S), bundled wood fiber, and mica, wherein the weight ratio of said cementitious inorganic powder and said material containing silica is set to be in the range of between 40 : 60 and 50 : 50. The bundled wood fiber has a bulky shape, and gives good toughness to said wood cement board, with the mica improving its dimensional stability. In a case where the C/S is set to be in the range of 40:60 and 50:50, the curing of said board proceeds smoothly, leaving little unreacted material remaining in the board.
Patent CA-2503952-A1 (CA)
Inventor: KLEIN JOHANN
IPC: C08K5/521
Filed: 2003-11-12
Abstract: The invention relates to a prepolymer containing at least one group of general formula (I) -X-A-Si(Z)n(OR)3-n (I), and optionally at least one group of general formula (II) -N(R1)-C(O)-Y-R2 (II), wherein R1 represents H or a linear or branched, saturated or unsaturated alkyl radical comprising between 1 and 18 C atoms; the radical R2 respectively represents a linear or branched, saturated or unsaturated alkyl radical comprising between 1 and 44 C atoms or a radical of general formula (III) R3-(O)-CHR4-CHR4)n- (III) wherein R3 represents a linear or branched, saturated or unsaturated alkylene radical comprising between 1 and 44 C atoms, and the radicals R4 independently represent H or a linear or branched alkyl radical comprising between 1 and 4 C  atoms; n represents a number between 1 and 1000; and Y represents O, S or NR2, R2 having the cited designation. The total number of functional groups I and II in the prepolymers amounts to more than 2. The invention also relates to compositions containing such prepolymers, to methods for the production thereof, and to the use of the same.
Patent CA-2504240-A1 (CA)
Title: Artificial fireplace
Inventor: ROSSEROT JEAN PIERRE
IPC: F21S10/04
Filed: 2005-04-14
Abstract: An artificial fireplace for simulating flaming logs has a housing containing a solid state light source, a rotating flame simulation assembly, a viewing screen, and a simulated fuel source. The solid state light source preferably comprises light emitting diodes (LEDs) affixed to a printed circuit board. The light produced by the LEDs reflects off of the rotating flame simulation assembly and an image of a flame is transmitted onto the viewing screen. This design creates a realistic, randomly-flickering flame image above the simulated fuel source. Optional features include a dimmer assembly to adjust the intensity of the image and a second light source to simulate smoldering embers within the simulated fuel source. This design eliminates the problems associated with using a light bulb for a light source by instead using LEDs with a longer life span which emit less undesirable heat and consume less electricity.
Patent CA-2504682-A1 (CA)
Title: Utilisation d'equol dans le traitement de maladies d'origine androgenique
Inventor: LEPHART EDWIN DOUGLAS
IPC: A61K31/35
Filed: 2003-10-29
Abstract: L'invention concerne de l'équol (7-hydroxy-3(4'hydroxyphényl)-chromane), la métabolite principale de la daidzéine phytoestrogène, se liant et bloquant de façon spécifique l'action hormonale de 5.alpha.-dihydrotestostérone (DHT) in vitro et in vivo. L'équol peut se lier à de la DHT libre circulante et la séquestrer du récepteur d'androgène, modifiant ainsi les réponses hormonales physiologiques et de croissance régulées par les androgènes. Ces données proposent un nouveau modèle d'explication des propriétés biologiques de l'équol. La signification de la capacité de l'équol à se lier et à séquestrer de façon spécifique la DHT du récepteur androgène possède d'importantes ramifications dans la santé et la maladie et peut indiquer une utilisation étendue et importante de l'équol dans le traitement et la prévention de pathologies d'origine androgénique. Ainsi, l'équol peut se lier de façon spécifique à la DHT et prévenir les actions biologiques de la DHT dans des traitements physiologiques et pathophysiologiques.
Patent CA-2504742-A1 (CA)
Title: Process for synthesis bis-aryl diamidoxime compounds
Inventor: TIDWELL RICHARD R
IPC: C07D307/02
Filed: 2003-11-25
Abstract: Bis-aryl diamidoxime compounds, such as 2,5-bis [4-hydroxy and 4-O- alkylamidinophenyl] furans, can be prepared from 2,5-bis tri-alkylstannanes via a one step palladium-catalyzed cross reaction. Bis-aryl diamidoxime compounds, such as 2,5-bis [4-hydroxy and 4-0-alkylamidinophenyl] furans, ar e useful as therapeutic compounds. The disclosed process is scalable, simpler, more economic and more feasible than other presently known methods of preparing 2,5-bis [4-hydroxy and 4-O-alkylamidinophenyl] furans and other bi s- aryl diamidoxime compounds.
Patent CA-2506815-A1 (CA)
Title: Power transmission system of vehicle
Inventor: CHONAN MITSUGI
IPC: F16H63/00
Filed: 2005-05-09
Abstract: The power transmission system for the vehicle of the present invention comprises a transmission having an input shaft and an output shaft, the input shaft being operatively connected to an engine, a counter shaft provided in parallel with the output shaft of the transmission, a forward gear train provided between the output shaft of the transmission and the counter shaft and a final reduction gear train provided between the counter shaft and an axle, the axle being operatively connected to the driving wheel . The forward gear train includes a gear having a diskportion mounted on the shaft and a circular gear portion fitted on an external circumference of the disk portion.
Patent CA-2507109-A1 (CA)
Title: Method of synthesis of 3d silicon colloidal photonic crystals by micromolding in inverse silica opal (miso)
Inventor: TETREAULT NICOLAS
IPC: C30B33/00
Filed: 2004-01-09
Abstract: A new type of synthetic silicon colloidal photonic colloidal crystal is described presenting a different topology than previously synthesised high refractive index contrast colloidal photonic crystals. It has been built using a new synthesis process based upon micromolding in inverse silica opals (MISO), where the micromold has a structure of interconnected air cavities in a silica matrix. By chemical vapour deposition of disilane within this micromold, a continuous and uniform silicon layer of controlled thickness is formed, which coats the walls of the silica matrix. Later, by dissolution of the starting silica micromold it is possible to oA new type of synthetic silicon colloidal photonic colloidal crystal is described presenting a different topology than previously synthesised high refractive index contrast colloidal photonic crystals. It has been built using a new synthesis process based upon micromolding in inverse silica opals (MISO), where the micromold has a structure of interconnected air cavities in a silica matrix. By chemical vapour deposition of disilane within this micromold, a continuous and uniform silicon layer of controlled thickness is formed, which coats the walls of the silica matrix. Later, by dissolution of the starting silica micromold it is possible to obtain a face centered cubic silicon colloidal photonic crystal with a topology never observed before and which presents a full photonic band gap, as indicated by theoretical photonic band structure calculations making them useful as optical components of envisioned all-optical microphotonic crystal devices, circuits, chips and computers.
Patent CA-2508147-A1 (CA)
Title: 2-nh-heteroarylimidazoles with antibacterial activity
Inventor: JARVEST RICHARD
IPC: C07D495/04
Filed: 2003-12-05
Abstract: 2-NH-Heteroarylimidazoles are inhibitors of bacterial methionyl tRNA synthetase and are of use in treating bacterial infections.
Patent CA-2508838-A1 (CA)
Inventor: BUHR WILM
IPC: C07D413/04
Filed: 2003-12-11
Abstract: L'invention a trait à des benzimidazoles substitués en position 6, représentés par la formule (I). Dans ladite formule, X représente O (oxygène) ou NH, et Y représente soit -CH¿2?-Ar, Ar étant un résidu aromatique mono ou bicyclique, ou Y représente le groupe représenté par la formule (gp), dans laquelle Z représente -CHR8- ou -CHR8-CHR9-. Les composés selon l'invention présentent une activité inhibitrice de la sécrétion gastrique, et des propriétés de protection gastrique et intestinale remarquables.