baber/WOPTO huggingface dataset:
Patent DK-0487611-T3 (DK)
Inventor: PRESTON CHRISTOPHER MAURICE
IPC: A61P43/00
Filed: 1990-08-14
Granted: 1996-05-20
Abstract: A herpes simplex virus type I (HSV-1) mutant capable of establishing latent infection in the absence of in vivo viral replication in neuronal cells and of expressing an inserted therapeutic gene, which comprising: (i) a DNA sequence change in the gene coding for Vmw65 protein, such as to substantially remove the transducing properties while retaining its structural role and thereby preventing in vivo replication, the DNA sequence change being achieved by a transition or transversion alteration of 1 to 72 base pairs, an oligonucleotide insert of 3 to 72 base pairs, or a deletion of 3 to 72 base pairs, at a position between amino acids 289 and 412 of the protein; and (ii) a therapeutic gene inserted into a region of the HSV-1 genome which is non-essential for culture of the virus, and a promoter therefor able to express the therapeutic gene in neuronal cells in vivo. The preferred insertion site for the therapeutic gene (e.g. tyrosine hydroxylase gene) is within the thymidine kinase gene of HSV in 1814.
Patent DK-0444186-T3 (DK)
Inventor: KALLAND TERJE
IPC: A61K35/74
Filed: 1990-09-14
Granted: 1996-01-02
Abstract: The present invention concerns a pharmaceutical composition for treating malignancies and autoimmune diseases involving cells expressing MHC class II antigens. The composition comprises a substance making said cells targets for cytotoxic T cells. The substance may be selected from the group consisting of staphylococcal enterotoxines, toxoids, active fragments or peptides of said enterotoxins and substances having essentially the same mode of action, such as Toxic Shock Syndrome toxins (TSST-1), bacterial exoproteins, such as streptococcal exoproteins, and proteins produced by mycoplasma arthritidis, which have capacity to interact with parts of the TCR and specifically the V beta chains thereof.
Patent DK-0497996-T3 (DK)
Inventor: PRINZ ECKHARD
IPC: H01T19/04
Filed: 1991-02-02
Granted: 1994-05-16
Abstract: The apparatus for the indirect corona treatment of conducting and nonconducting materials, for example sheets of plastic, paper, metal and/or fabric or mouldings made of these materials, is used to increase the surface energy with the aid of two electrodes situated on the same side of the material to be pretreated, which moves with respect to them. Pressurised gas is fed to the discharge gap between the electrodes in order to deflect the discharge arc in a suitable manner. The appropriate electrical voltage is generated by a transformer (1). The two electrodes take the form of bare metal electrodes (12) and they form a pair of pin electrodes. There is no dielectric on either of the two electrodes. If both electrodes are live, a capacitor (13, 14) is inserted between the two electrodes and the transformer. If only one electrode (12) is live, a suitable capacitor (13) is provided for this electrode alone, while the other electrode is at earth. The purpose of the dielectric in conventional apparatuses is virtually assumed by the condenser or condensers. The gas stream provided for each electrode pair provides the appropriate deflection of the spark channel in the direction of the surface to be treated. This results in a simple and compact treatment unit which can be used universally and achieves a very good treatment result with a very simple construction (Fig. 3A). <IMAGE>
Patent DK-0456080-T3 (DK)
Inventor: ZEITSCHEK RUDOLF DIPL-ING
IPC: G08B29/02
Filed: 1991-04-29
Granted: 1997-02-17
Abstract: A method and a circuit are described for indicating different input signal states, in which a signalling device is activated or de-activated continuously or intermittently. This happens in such a way that levels (U2, U3) are provided for intermittent operation which differ from the levels for continuous activation (U4) or de-activation (U1). <IMAGE>
Patent DK-0478892-T3 (DK)
Inventor: SCHMIDT RAINER
IPC: H04R25/02
Filed: 1991-05-24
Granted: 1995-04-10
Abstract: An in-the-ear hearing aid has an otoplasty element (16) with a face plate (12) closing it off. Arranged on the face plate is a decorative element (28) which is designed in two parts. A base plate is connected mechanically, for example locked, to the face plate (12), and a cover plate (32) is connected pivotally to the base plate (30) by means of a pivot pin (34). The base plate (30) has an opening (36) in the middle area, through which access can be gained to setting means (22) and the battery compartment (20) when the cover plate (32) is pivoted to the side. <IMAGE>
Patent DK-0457702-T3 (DK)
Inventor: PFALZGRAF EMILE
IPC: B23B29/034
Filed: 1991-05-14
Granted: 1995-07-17
Abstract: The present invention relates to a boring head constituted by a body (1) provided with a radial piston (2) for reception of a boring tool (3) gripped by means of a screw (4), said piston (2) being adjustable in position by means of a micrometric screw (5), characterized in that the body (1) is provided also with a slide block (6) effecting the guidance, the orientation and an end-of-movement abutment for the piston (2) for reception of the boring tool (3) and with a balancing device (7) with independent counterweights (8 and 9).
Patent DK-0530060-T3 (DK)
Inventor: GRIMBERG GEORGES SERGE
IPC: A61K35/08
Filed: 1992-07-20
Granted: 1997-03-17
Abstract: The medicine comprises a neutralizing association of a sulphide with a yeast extract.
Patent DK-0575499-T3 (DK)
Inventor: WITTEVEEN GUSTAAF JAN
IPC: B05B7/10
Filed: 1992-03-19
Granted: 1996-06-03
Abstract: Device for mixing gas, liquids or pulverised solid substances with a gas flow (1), whirling (vortex) around an axis in the flow direction. The whirling gas flow is guided through a converging passage (4) and, during or after being charged with the substance, abruptly widens in cylindrical space (11), as a result of which vortex break down occurs and an exceptionally thorough mixing and/or atomizing of the substance is obtained. Application in a burner improves the combustion result, keeps the NOX-values low and prevents the flame from being blown off.
Patent DK-0643069-T3 (DK)
Inventor: TAKEUCHI TOMIO
IPC: C07H19/052
Filed: 1992-11-13
Granted: 1997-09-15
Abstract: 2'-Deoxy-2'-fluorocoformycin and 2'-deoxy-8-epi-2'-fluorocoformycin have now been synthesized by a multistage reaction via 3,5-di-O-benzoyl-2-deoxy-2-fluoro- alpha - and - beta -D-ribofuranosyl bromide. Also 2'-deoxy-2'-epi-2'-fluorocoformycin and 2'-deoxy- 8,2'-diepi-2'-fluorocoformycin have been synthesized from 3,5-di-O-benzoyl-2-deoxy-2-fluoro- alpha -D-arabinofuranosyl bromide by a multistage reaction. These four 2'-fluorocoformycin derivatives are novel compounds and have a potent enzyme inhibiting activity against adenosine deaminase. In particular, they are useful for treating acute lymphocytic leukemia in virtue of the above activity. Other novel compounds also obtained include various intermediates useful for the synthesis of the above derivatives.
Patent DK-0642486-T3 (DK)
Inventor: BURGESS LESLIE
IPC: C07B61/00
Filed: 1992-12-03
Granted: 1999-12-06
Abstract: A process for the production of a hydro(halo)fluorocarbon which comprises heating an  alpha -fluoroether in the vapor phase at elevated temperature.  alpha -fluoroethers are obtained by reacting a non-enolizable aldehyde with hydrogen fluoride to form an intermediate and reacting the intermediate with an alcohol or a halogenating agent. Novel  alpha -fluoroethers are also provided.
Patent DK-0556706-T3 (DK)
Inventor: NI FONG-MING
IPC: A45B25/18
Filed: 1993-02-10
Granted: 1996-05-20
Abstract: A method for forming a cover (85) of an umbrella including preparing several pieces of cloth (41), clamping the perimeters of the cloth (41) and pulling the cloth (41) downward against a lower mold (69) having a convex shape, heating the lower mold (69) in order to soften the cloth (41), moving an upper mold (70) downward to clamp the cloth, heating the lower mold (69) again in order to further increase the temperature of the lower mold (69) so that the cloth (41) can be hot-pressed, cooling the lower mold (69), removing the cloth (41), and cutting the perimeter of the cloth so as to form the cover (85) of the umbrella. <IMAGE>
Patent DK-0590412-T3 (DK)
Inventor: FLECKENSTEIN VOLKER DIPL-ING
IPC: H04L12/40
Filed: 1993-09-15
Granted: 1999-08-16
Abstract: Various modules of the mobile radio base station are connected to one another by a bus system via which the data are transmitted in parallel and are extended in parallel with check bits for error detection and error correction. A bus controller supplies a reference clock and other timing clocks. Transmission on the bus is carried out in the form of addressed data packets within a time slot. The bus system is constructed of individual modules to which the information data rate occurring per time interval is distributed. The modules can be placed against one another in such a manner that each module is connected to each module (star structure). In addition, control data must be transmitted to the hardware devices, for the flexible and rapid exchange of which a special control method based on a logical ring of hardware units is defined. <IMAGE>
Patent DK-0610576-T3 (DK)
Inventor: SCHOENER PETER DR
IPC: B09B3/00
Filed: 1993-12-13
Granted: 1997-10-06
Abstract: Glass and metal are recovered separately from the solid residues produced in a refuse incineration plant, in particular from slag, by melting. The melting is carried out in two zones. In the first, upper melting zone, the oxidic constituents of the residues are converted into a glass melt. In the second, lower melting zone, the metallic constituents of the residues are converted into a metal melt at elevated temperature. The two melts are isolated separately.
Patent DK-0642528-T3 (DK)
Inventor: GOSSELIN GILLES
IPC: A61K31/7042
Filed: 1993-05-24
Granted: 1997-07-21
Abstract: Compounds of formula RS-P(=O)(QR)-Nu where: R is a radical -(CH2)n-W-X; X is a radical -C(=Z) (Y) or -S-U; Z is O or S; W is O or S; Q is O or S; Y and U are an alkyl, aryl or saccharide radical which is optionally substituted with, for example, an OH, SH or NH group; n is equal to 1 to 4, preferably 1 or 2; and Nu is a radical consisting of a residue of a biologically active compound or the dephosphorylated residue of a compound which is biologically active when it bears a phosphate or phosphonate group.
Patent DK-0646164-T3 (DK)
Inventor: HUBER ALAN CARL
IPC: C11D1/94
Filed: 1993-06-01
Granted: 1997-11-03
Abstract: This invention relates to homogeneous liquid laundry detergent compositions containing polyhydroxy fatty acid amide, silicone antifoam composition, and anionic, nonionic or amphoteric surfactant. The silicone antifoam composition includes polyethylene glycol or a copolymer of polyethylene-polypropylene glycol having a solubility in water at room temperature of more than about 2 weight %.
Patent DK-0662446-T3 (DK)
Inventor: BEGEMANN DIRK
IPC: B60G9/02
Filed: 1994-04-29
Granted: 1999-08-09
Abstract: The frame has a front axle cross-bearer on which steerable wheels are fitted and also has rear wheels. The front axle cross-bearer (6) is pivotable around an axis (B) in the travel frame longitudinal direction and can be fixed in its pivot positions. The rear wheels (12) are arranged on guides (11) which are each height-adjustable. To the front axis cross-bearer is linked a double-acting hydraulic cylinder (10) which can be blocked and unblocked by valves and forms the locking device of the front axle cross-bearer. The height adjustment devices of the rear wheels comprise hydraulic cylinders (13) fixed to the frame and counter located, engaging on the guides (11).
Patent DK-0654584-T3 (DK)
Inventor: FOHNLE GERHARD
IPC: F01B13/06
Filed: 1994-09-21
Granted: 1999-03-08
Abstract: The invention relates to a hydrostatic radial piston machine with two rotors (17, 18) which are mounted to allow easy rotation on a spindle and which have a plurality of radially extending holes with displacer elements (piston plus sliding block 15, 14) sliding on the inside of a cam ring (8, 9). For control of the delivery of the pressure medium, the holes are connected via control slots (21, 22) to delivery passages (high-/low-pressure 27, 28) opening at the sides of the rotors. The invention is characterised in that the two rotors (17, 18) are mounted in an easily rotatable manner on a spindle (43) installed rigidly in an intermediate plate (5), in that the intermediate plate (5) is situated between the rotors (17, 18), in that thrust washers (37, 44) which accept the axial forces caused by the pressure medium in the control slots (21, 22) of the rotors (17, 18) are mounted on the ends of the spindle (43), and in that the cam rings (8, 9) are mounted in the intermediate plate by way of a common connecting shaft (10). <IMAGE>
Patent DK-0611123-T3 (DK)
Inventor: KEYES DENIS E
IPC: A61F5/445
Filed: 1994-02-07
Granted: 2000-01-03
Abstract: The ostomy pouch 10 has a coupling member 32 that can be removed from the pouch envelope to permit flush disposal of the envelope without the coupling member. Flushability of the pouch is further enhanced by forming the pouch with converging side walls 20, 22. Thus, when the pouch 10 is deposited in a toilet bottom end first in a carrier sleeve, the pouch can flow in streamlined fashion through the passages of a toilet and any sewer pipe or septic line connected to the toilet. Depending upon the flush capacity of the toilet and the flow rate of water through the toilet and sewer line, the ostomy pouch can be deposited in the toilet without a carrier sleeve. <IMAGE>
Patent DK-0687176-T3 (DK)
Inventor: BOUSSEAU ANNE
IPC: C07D277/82
Filed: 1994-02-25
Granted: 2001-07-30
Abstract: The invention relates to the application of riluzole or the pharmaceutically acceptable salts of this compound in the treatment of neuro-AIDS.
Patent DK-0700393-T3 (DK)
Inventor: PLATZEK JOHANNES
IPC: C07D257/02
Filed: 1994-04-29
Granted: 1998-07-20
Abstract: PCT No. PCT/EP94/01377 Sec. 371 Date Mar. 19, 1996 Sec. 102(e) Date Mar. 19, 1996 PCT Filed Apr. 29, 1994 PCT Pub. No. WO94/27978 PCT Pub. Date Dec. 8, 1994The invention relates to new fluorine-containing macrocyclic metal complexes that consist of a complexing agent of formula I and at least one metal ion of an element of atomic numbers 21-29, 42, 44 or 57-83    <IMAGE>  (I)  in which n, R1, R2, R3 and A have a different meaning, agents containing these compounds, their use as NMR and x-ray diagnostic agents as well as process for the production of these compounds and agents.
Patent DK-0652968-T3 (DK)
Inventor: IMLER JEAN-LUC
IPC: C12N7/01
Filed: 1994-05-27
Granted: 2001-06-11
Abstract: New replication-defective adenoviruses are selected from: (a) those that are derived from a natural adenovirus and lack at least the coding sequences of the E1B region and/or at least part of the E4 region; (b) those that are derived from a natural adenovirus other than a human type 5 adenovirus (Ad5) and lack part of the encapsidation region; (c) those that are derived from Ad5 and lack the part of the encapsidation region corresp. to nucleotides 270-346 in the Genbank M73260 sequence; and (d) those that are derived from Ad5 and lack the part of the encapsidation region corresp. to nucleotides 184-273 in the Genbank M73260 sequence. Also claimed is a eukaryotic cell contg. an adenovirus as above. Also claimed are: (1) a complementation line comprising a cell line contg. a complementation element which comprises at least part of the E1 region of a natural adenovirus and lacks the 5' ITR sequence, the element being integrated into the genome or inserted into a vector: and (2) a process for producing a defective adenovirus as above, comprising introducing the virus into a complementation line as above, culturing the cell line, and recovering the virus from the culture supernatant.
Patent DK-0720026-T3 (DK)
Inventor: ONO MIYOKO
IPC: G01N24/10
Filed: 1995-12-28
Granted: 2000-09-18
Abstract: Quantitative determination and evaluation of the flavor stability of fermented alcoholic beverages are performed by measuring the changes of the amounts of spin adduct from the formation behavior of active oxygen with passage of time using an ESR apparatus and either determining the value on the time axis of the inflection point of changes of the amounts of spin adduct (defined as the active oxygen formation lag time) or determining the amount of spin adduct after a predetermined time has elapsed after the start of measurement (defined as the active oxygen formation activity). The longer the active oxygen formation lag time or the lower the active oxygen formation activity, the greater the oxygen resistance of the fermented alcoholic beverage, thus making it possible to evaluate that fermented alcoholic beverage as having good flavor stability. In addition, if the formation behavior of active oxygen of semi-finished products in the production process is measured in the same manner, the quality of flavor stability when that semi-finished product has become a finished product can be predicted and evaluated.
Patent DK-0739107-T3 (DK)
Inventor: SCHWENK JOERG DR RER NAT
IPC: H04L9/30
Filed: 1996-01-18
Granted: 2000-11-06
Abstract: The method is based on the difficulty of factorising large numbers, natural numbers. A public key is used to encode a data set and to form a secret key, known only to each user (B). The user (A) encodes the data so that the data is accessible only to the user (B), with the aid of the secret key. The data set m, a set of numbers, is encoded by the aid of a number n, the product of two large prime numbers p + q and the set m is split up into blocks, m1, m2,...mk, with numbers smaller than n.
Patent DK-0846181-T3 (DK)
Inventor: SPIELHOFER PIUS
IPC: A01N65/00
Filed: 1996-08-09
Granted: 2005-07-04
Abstract: The present invention relates, in general, to a methodology for the generation of nonsegmented negative-strand RNA viruses (Pringle, 1991) from cloned deoxyribonucleic acid (cDNA). Such rescued viruses are suitable for use as vaccines, or alternatively, as plasmids in somatic gene therapy applications. The invention also relates to cDNA molecules suitable as tools in this methodology and to helper cell lines allowing the direct rescue of such viruses. Measles virus (MV) is used as a model for other representatives of the Mononegavirales, in particular the family Paramyxoviridae. <IMAGE>
Patent DK-0850278-T3 (DK)
Inventor: HARVEY C TUNG
IPC: C09J7/02
Filed: 1996-08-12
Granted: 2000-07-10
Abstract: A deformable label comprising a printable film facestock having at least one layer containing incompatible polymers. The printable film facestock exhibits significantly reduced die-face buildup during extrusion of the printable film facestock when compared to the die-face buildup exhibited by film facestock of the prior art. The present invention provides for monolayer film facestock containing incompatible polymers and colorants. The present invention also allows printable film facestock to be produced in a more cost-effective manner.
Patent DK-0803626-T3 (DK)
Inventor: ERIKSSON MATS JOHAN
IPC: E06B3/44
Filed: 1997-04-04
Granted: 2000-11-06
Abstract: The door is raised vertically by a drum (14), driven by an electric motor, which activates operating links fastened to the door. The motor is coupled to an intermediate plate (34), which has a predetermined rotational play, on the drum fixed support (20). A pawl (36), mounted near the drum and coupled to the intermediate plate, pivots into a predetermined position to engage a stop (28) when the intermediate piece is rotated consecutively consequent to a failure of the door retainer. The fixed support forms a bearing for the shaft (16) to which the drum is fixed. The intermediate plate, which is located in an axial extension of the shaft, has rectangular holes (38) in which guide bolts (40) are engaged. A spring (48) between the fixed support and intermediate piece assists the latter into a stable position when the pawl is distanced from the stop.
Patent DK-0904064-T3 (DK)
Inventor: PERRY ELIZABETH ANNE
IPC: A61K9/48
Filed: 1997-04-28
Granted: 2001-12-17
Abstract: A pharmaceutical composition comprising: a hydrophobic drug, a digestible oil selected from triglycerides or propylene glycol esters of medium chain length (C8-C12) and/or long chain length (C13-C22) fatty acids; and propylene glycol monolaurate, a lipophilic surfactant which comprises a glyceride of a C5 to C10 fatty acid and a hydrophilic surfactant which is a polyoxyethylene hydrogenated castor oil, wherein the digestible oil is present in an amount on the range from 3.0 to 12.0 % by weight of the composition and the weight ratio of hydrophilic surfactant to lipophilic surfactant is in the range 1:1.5 to 1:2.5. Suitable hydrophobic drugs includes sex hormones such as progesterone, oestradiol and testosterone.
Patent DK-0922870-T3 (DK)
Inventor: CLAUS WOLFGANG DIPL-ING
IPC: G01M13/04
Filed: 1998-11-03
Granted: 2004-09-06
Abstract: A device for measuring wear in large roller bearings that have two bearing rings (1 & 2) with space accommodating the rollers (3) between them. The device has an indicator that indicates a prescribed deflection between the rings and a probe (9) that is accommodated in an opening (10) in the outer bearing ring (2) with the end (11) of the probe able to come into contact with one of the surfaces of the inner bearing ring (1). The object is a device that will provide accurate and reliable indications of bearing wear even after years of use, that will be simple in design, and that cannot be damaged or destroyed by outside forces. The inner bearing ring accordingly has a groove (12) facing the probe, and the end of the probe extends into the groove. The surfaces of the groove are as far from the end of the probe as the maximal permissible depth of the wear on the bearing.
Patent DK-0884308-T3 (DK)
Inventor: V D VELDE J P
IPC: A61P35/00
Filed: 1998-04-28
Granted: 2003-07-21
Abstract: The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I <CHEM>  wherein:   R has the epi-configuration or the normal configuration and represents straight or branched C1-6-alkyl, C2-6-alkenyl, C3-6-cycloalkyl, or an aromatic group optionally substituted with halogen, C1-3-alkyl or alkoxy, Z is a saturated or unsaturated straight hydrocarbon group or oxahydrocarbon group containing 3-6 C-atoms which may be substituted with OH, F, alkyl (C1-3) or cycloalkyl (C3-5),   R1 is hydrogen or an hydroxy protecting group,   R2 is hydrogen or hydroxy, and A and B represent hydrogen or methyl, or together form the methylene group, to the new compounds having this formula and to new intermediates obtainable according to this process.
Patent DK-1004369-T3 (DK)
Inventor: VANDEN BRANDE PIERRE
IPC: B21B45/00
Filed: 1998-11-26
Granted: 2004-09-27
Abstract: Sealing chamber comprises enclosure (1) containing at least three successive rollers (2a, 2b, 2c) in strip movement direction. First and third rollers are located on one side of passage between rollers, and second roller is situated on opposite side. Sealed zone is formed between strip and first and third rollers and connected to pump. Devices are provided for regulating strip pressure on rollers. Devices are provided for regulating the distance between at least two successive rollers (2a) and (2b) or (2b) and (2c), and for tensioning the strip (3) so that the strip (3) can recover the difference in pressure existing between two consecutive zones. Sealing elements (4) are provided between the wall of the enclosure (1) and the rollers (2a, 2b, 2c). The strip is especially a steel strip.