baber/WOPTO huggingface dataset:
Patent MX-2020013051-A (MX)
Title: Simplified method for the adsorption of active principles on the surface of functionalized nanoparticles.
Inventor: TREVIÑO MARTÍNEZ MARÍA ESTHER
IPC: A61K9/51
Filed: 2020-12-01
Abstract: The present invention relates to a simplified method to achieve the adsorption of active ingredients on the surface of functionalized nanoparticles, performed at low temperatures to avoid thermal degradation of the active ingredient. The said method consists of a) preparing a solution of the active principle in an organic solvent with low solubility in water, b) preparing an aqueous dispersion with the functionalized nanoparticles, c) putting the two liquids in a container, and d) shaking it to disperse one liquid in the other, generating a contact area between the phases (interfacial area), allowing the transfer of the active ingredient from the organic phase to the aqueous phase. Also, it involves e) continuing with the agitation until reaching equilibrium in the distribution of the active ingredient between the two solutions, f) stopping stirring and leaving the container at rest for the separation of the organic and the aqueous phase, g) recovering the aqueous phase containing the nanoparticles, absorbing the active ingredient molecules, h) recovering the organic phase, adding more active ingredient for using it again in another loading operation.
Patent MX-2020013491-A (MX)
Title: Hot press-formed item manufacturing method, press-formed item, die, and die set.
Inventor: SUZUKI TOSHIYA
IPC: B21D24/04
Filed: 2019-07-03
Abstract: A hot press-formed item manufacturing method wherein a die 11 has, in the entire region adjacent to a die shoulder section 11B within a steel plate contact surface 11A, a hard layer 11C having a hardness Hv_Die of HV1000 to 1800 and a skewness (Rsk) of -5.0 to 1.2 as measured in a direction from the outside of a die hole 11D toward the inside, said steel plate contact surface 11A being a surface to the outside of the die hole 11D and contacting a galvanannealed steel sheet 10 prior to the same being subjected to hot press-forming.
Patent MX-2021000623-A (MX)
Title: Thermal insulating composition based on fumed silica granulates, processes for its preparation and uses thereof.
Inventor: NUMRICH UWE
IPC: C04B111/28
Filed: 2019-07-08
Abstract: Thermal insulating composition based on silica granulates The present invention relates to: - a thermal insulating composition, containing 5 to 60 % by weight of a hydrophobized granular material comprising fumed silica and at least one IR-opacifier, and 40 to 95 % by weight of an inorganic and/ or an organic binder, whereby the hydrophobized granular material has a content of free hydroxyl groups of no greater than 0.12 mmol/g as determined by the reaction with lithium aluminium hydride. - the use of this composition for thermal and/or acoustic insulation of walls, roofs, houses, industrial plants, parts of industrial apparatuses, pipelines. - two alternative processes for producing a thermal insulating composition, comprising the following steps: a) mixing a hydrophilic fumed silica with at least one IR-opacifier; b) densifying the mixture obtained in step a) to give a hydrophilic granular material; c-1) subjecting the hydrophilic granular material produced in step b) to thermal treatment at a temperature of 200 to 1200Â°C; OR c-2) treating the hydrophilic granular material produced in step b) with ammonia; d) hydrophobizing the hydrophilic granular material subjected to thermal or chemical treatment in step c) with a hydrophobizing agent to obtain a hydrophobized granular material; e) mixing the hydrophobized granular material produced in step d) with an inorganic and/or an organic binder.
Patent MX-2021000665-A (MX)
Title: Composition comprising glycyrrhin and cosmetic and pharmaceutical uses thereof.
Inventor: SANSÒ MARCO ALDO
IPC: A61K8/00
Filed: 2019-07-15
Abstract: The invention discloses a composition comprising glycyrrhizin, hyaluronic acid or a salt or a derivative thereof, and a viscosizing agent. The composition therefore finds advantageous application in all those cosmetic and therapeutic indications in which glycyrrhizin is used, since the composition according to the invention significantly improves the bioavailability thereof.
Patent MX-2021001326-A (MX)
Title: Structure for assembling apparatus.
Inventor: BUSUIOC CONSTANTIN S
IPC: B62D21/00
Filed: 2021-02-02
Abstract: A structure for assembling a vehicle having an axis of elongation, a frame rail and a cross member extending from the frame rail comprises a conduit extending along the axis of elongation of the vehicle. A conveyor is disposed in the conduit. At least one coupling attaches the conduit with at least one of the frame rail and the cross member.
Patent MX-2021001971-A (MX)
Title: Methods for manufacturing plant messenger packs.
Inventor: MARTIN BARRY ANDREW
IPC: A01G31/06
Filed: 2019-08-24
Abstract: Disclosed herein are methods, and related bioreactors, for manufacturing plant messenger packs (PMPs), which can be formulated for use in a variety of agricultural and therapeutic methods.
Patent MX-2021002590-A (MX)
Title: Methods of using a phenoxypropylamine compound to treat pain.
Inventor: NOEL NADINE
IPC: A61K31/454
Filed: 2019-09-04
Abstract: The present disclosure relates to methods of treating pain, fibromyalgia, neuropathy, chemotherapy-induced pain, promoting an antihyperalgesic effect, and reducing sensitivity to pain, in a subject in need of such treatment comprising the administration of a therapeutically effective amount of Compound I, or a pharmaceutically acceptable salt, solvate, or prodrug thereof.
Patent MX-2021004280-A (MX)
Title: Pyrazole derivatives as h4 antagonist compounds.
Inventor: BROWN GILES ALBERT
IPC: C07D487/04
Filed: 2019-10-21
Abstract: The disclosures herein relate to novel compounds of formula (1): and salts thereof, wherein A; X;n; R<sup>1</sup> and R<sup>2 </sup>are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with H4 receptors.
Patent MX-2021004291-A (MX)
Title: Treatment of metastatic pancreatic adenocarcinoma.
Inventor: SORANI ELLA
IPC: A61K35/18
Filed: 2019-10-17
Abstract: A method of treating metastatic pancreatic adenocarcinoma in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of each of a peptide set forth in SEQ ID NO: 1, an anti PD-1 and a chemotherapy, thereby treating the metastatic pancreatic adenocarcinoma.
Patent MX-2021006179-A (MX)
Title: Pet foods comprising gravy topping comprising methylcellulose and methods of making such pet foods.
Inventor: WATELAIN ANNIE
IPC: A23K20/163
Filed: 2019-12-20
Abstract: A multi-layered pet food can contain a first edible composition that is a gravy comprising methylcellulose; and a second edible composition having a flat upper surface against which the gravy is positioned. A method of preparing a multi-layered pet food can include: preparing a first edible composition that is a gravy at a first temperature, the gravy comprising methylcellulose; filling the gravy into a container; heating the gravy in the container to a second temperature to jellify the gravy; and filling a second edible composition into and on top of the first layer. The multi-layered pet food can be administered to a pet such as a companion animal.
Patent MX-2021007190-A (MX)
Title: Tree-based transform unit (tu) partition for video coding.
Inventor: KARCZEWICZ MARTA
IPC: H04N19/176
Filed: 2019-12-17
Abstract: A video decoder may receive, in a bitstream that comprises an encoded representation of video data, information indicating whether a residual block is partitioned and information indicating a partition tree type for the residual block based on the residual block being partitioned, wherein the residual block is indicative of a difference between a current block and a prediction block. The video decoder may determine, based on the received information that the residual block is partitioned and the partition tree type for the residual block, a plurality of residual sub-blocks into which the residual block is partitioned according to the partition tree type. The video decoder may produce the residual data for the current block based at least in part on the residual block being partitioned according to the partition tree type into the plurality of residual sub-blocks and may decode the current block using the residual data.
Patent MX-2021007948-A (MX)
Title: Inhibitors of fibroblast activation protein.
Inventor: BERNALES SEBASTIAN
IPC: A61K31/275
Filed: 2020-01-03
Abstract: Compounds and compositions for modulating fibroblast activation protein (FAP) are described. The compounds and compositions may find use as therapeutic agents for the treatment of diseases, including hyperproliferative diseases.
Patent MX-2021008066-A (MX)
Title: Steel plate and manufacturing method thereof.
Inventor: KAWATA HIROYUKI
IPC: C22C38/00
Filed: 2020-01-07
Abstract: This steel plate has a prescribed chemical composition: the metal composition of the surface layer region, which is the area from the surface to the position 20 µm from said surface in the plate thickness direction, comprises ferrite and a second phase with a 1.0-15.0% volume fraction; the metal composition of the inner region, which is the area from the position over 20 µm from the surface in the plate thickness direction to the position 1/4 of the plate thickness from the surface in the plate thickness direction, comprises ferrite and a second phase with a 5.0-25.0% volume fraction; and the second phase volume fraction in the surface layer region is smaller than the second phase volume fraction in the inner region, wherein, in the surface layer region, the average grain size of the second phase is 0.5-4.0 µm, and aggregate structures are included in which the intensity ratio XODF{001}/{111} of the {001} orientation and the {111} orientation of the ferrite is 0.70-2.50.
Patent MX-2021008340-A (MX)
Title: Image prediction method, device, apparatus and system and storage medium.
Inventor: ZHANG LIAN
IPC: H04N19/107
Filed: 2020-01-08
Abstract: Disclosed are an image prediction method, device, apparatus and system as well as a storage medium. The method comprises the following steps: obtaining a division mode of a current node (401), the current node being an image block of a coding tree unit in a current image; according to the division mode and size of the current node, determining whether the current node satisfies a first condition (402); and when the current node is determined to satisfy the first condition, performing intra-frame prediction on all coding blocks belonging to the current node, so as to obtain prediction values of all coding blocks belonging to the current node (403). The described method performs intra-frame prediction on all encoding blocks of the current node, thereby realizing parallel processing of all encoding blocks of the current node, improving the processing performance of image prediction, and increasing the processing speed of encoding and decoding.
Patent MX-2021009756-A (MX)
Title: Systems and methods for ultralow field relaxation dispersion.
Inventor: DE MATOS GOMES MULLER FRANCIS
IPC: G01R33/385
Filed: 2020-02-14
Abstract: A system of field cycled magnetic resonance system and a method of operating a field cycled magnetic resonance system are described. In accordance with various embodiments, the disclosed system includes a static field magnet, wherein the magnet is configured to provide a low static external magnetic field to a given field of view, a radio frequency coil, and a field cycling magnet. In accordance with various embodiments, the method includes providing a static field magnet configured to image a tissue sample within a given field of view, applying a low static external magnetic field to the given field of view, providing a radio frequency coil configured to produce cycling radio frequency field, providing a field cycling magnet, altering the low static external magnetic field within the given field of view, and collecting images from the system.
Patent MX-2021011275-A (MX)
Title: Saponin-based vaccine adjuvants.
Inventor: WANG PENGFEI
IPC: A61K47/28
Filed: 2020-03-17
Abstract: A number of MS- and natural-saponin-based vaccine adjuvant candidates have been prepared. The MS derivatives were prepared by incorporating a terminal-functionalized side chain into the C3 glucuronic acid unit of the natural saponins MS I and II through amide formation reaction; and the QS analogs were prepared via multi-step organic synthesis. These unnatural saponins showed significantly different immunostimulant activity profiles, suggesting that the structure of side chain, triterpenoid core, and oligosaccharide domain together orchestrate each saponin's characteristic potentiation of immune responses.
Patent MX-2021012290-A (MX)
Title: Pesticidally active diazine-amide compounds.
Inventor: PITTERNA THOMAS
IPC: C07D403/04
Filed: 2020-04-07
Abstract: Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides.
Patent MX-2021014644-A (MX)
Title: Automated biomass-based perfusion control in the manufacturing of biologics.
Inventor: KHURSHID MADIHA
IPC: C12M1/00
Filed: 2020-06-15
Abstract: The present invention provides an adapted perfusion or continuous perfusion manufacturing process comprising an automated biomass-based controlled perfusion rate which ensures a more efficient process. Hence, a process according to the present invention is more manufacturing friendly and operational friendly. Also provided are an apparatus to perform such a process and a biologic produced by such a process. The process comprises a first control loop for measuring and regulating medium level in the bioreactor and a second control loop for measuring and regulating the biomass in the bioreactor, comprising a permittivity probe or a Raman probe. First and second control loops are integrated using an integration unit.
Patent MX-2021014985-A (MX)
Title: Sliding laminated glazing with internal side overhang.
Inventor: WESSBERG HENRIK
IPC: B32B3/02
Filed: 2020-06-03
Abstract: The invention relates to a vehicle glazing (1), comprising a glass pane (2) comprising at least one external glass sheet (3), an internal glass sheet (5), as well as an adhesive material sheet (4), the glass pane (2) having an upper edge (25), a lower edge (26), a first side edge (23) and a second side edge (24); the external glass sheet (3) and the internal glass sheet (5) are each a glass sheet that has been thermally toughened or semi-toughened, the rim of the internal glass sheet (5) being located beyond the rim of the adhesive material sheet (4) and the rim of the external glass sheet (3) only on at least one portion, even all, of the length of the first side edge (23) and/or on at least one portion, even all, of the length of the second side edge (24) of the glass pane (2).
Patent MX-2022002014-A (MX)
Title: Aluminum metal matrix composite sheaths for wire electrodes.
Inventor: BUNDY JOSEPH
IPC: B23K35/36
Filed: 2020-08-28
Abstract: The present disclosure relates to tubular welding electrodes that have a metallic sheath surrounding a granular core, wherein the metallic sheath comprises a metal matrix composite (MMC) that includes a ceramic material and aluminum or an aluminum alloy. The ceramic material may be in the form of microparticles or nanoparticles. The present disclosure also relates to method for making such tubular welding electrodes.
Patent MX-2022002458-A (MX)
Title: Method of isolating circulating nucleosomes.
Inventor: ECCLESTON MARK EDWARD
IPC: G01N33/574
Filed: 2020-08-27
Abstract: The invention relates to methods for separating circulating cell free nucleosomes comprising linker DNA from a biological fluid sample, in particular nucleosomes of disease origin. Such methods allow for improved analysis of genetic and epigenetic markers associated with nucleosomes of disease origin.
Patent MX-2022002852-A (MX)
Title: Biomarkers and treatments of alzheimer's disease and mild cognitive impairment.
Inventor: ZILKA NORBERT
IPC: A61K38/04
Filed: 2020-09-08
Abstract: The disclosure provides immunogenic peptides, compositions, means, and methods for treating Alzheimer's disease or mild cognitive impairment. The disclosure turther provides means and methods for diagnosing patients, selecting patients for treatment, and/or evaluating the efficacy of treatment for Alzheimer's disease or mild cognitive impairment.
Patent MX-2022005850-A (MX)
Title: Modified immunoglobulins for targeting amyloid deposits.
Inventor: WALL JONATHAN S
IPC: C07K16/18
Filed: 2020-11-13
Abstract: Provided herein are modified immunoglobulins comprising an amyloid reactive peptide joined to an antibody, as well as humanized antibodies that bind to human amyloid fibrils and antibody-peptide fusion proteins. Also provided herein are methods of treating amyloid-based diseases by administering a modified immunoglobulin, humanized antibody, or antibody-peptide fusion protein.Provided herein are modified immunoglobulins comprising an amyloid reactive peptide joined to an antibody, as well as humanized antibodies that bind to human amyloid fibrils and antibody-peptide fusion proteins. Also provided herein are methods of treating amyloid-based diseases by administering a modified immunoglobulin, humanized antibody, or antibody-peptide fusion protein. In one aspect, the present disclosure relates to compounds and compositions capable of inhibiting TACC3. In another aspect, the present disclosure relates to methods of treating TACC3 mediated diseases and disorders.
Patent MX-2022006380-A (MX)
Title: Method and system for detection of extraintestinal e. coli strains pathogenic to poultry.
Inventor: STANCZYK MALGORZATA
IPC: C12Q1/689
Filed: 2020-11-26
Abstract: A rapid method has been disclosed that allows for the unequivocal identification of extraintestinal E. <i>coli</i> strains pathogenic for poultry using a new combination of genes amplified in a multiplex PCR diagnostic method.
Patent MX-2022006507-A (MX)
Title: Angiopoietin-like 3 (angptl3) irna compositions and methods of use thereof.
Inventor: FITZGERALD KEVIN
IPC: C12N15/113
Filed: 2017-10-11
Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting epression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.
Patent MX-2022006957-A (MX)
Title: Machine tools and methods of operation thereof.
Inventor: TUCKER MATTHEW
IPC: B23Q1/48
Filed: 2020-12-08
Abstract: A machine tool comprises first and second rotary machine axes (10,16) which are parallel and mounted on a base in fixed locations relative to the base, a linear machine axis (8) which is carried by the first rotary machine axis, and a rotary positioning mechanism (30) which is carried by the linear machine axis, wherein the rotary positioning mechanism provides rotation about a support rotational reference axis (32) that is parallel to the first and second rotary machine axes. A further machine tool includes a linear positioning mechanism (40) which is carried by the linear machine axis that provides linear movement parallel to the linear machine axis. The rotary and/or linear positioning mechanisms enable the workzone of the machine tool to be extended and/or reconfigured.
Patent MX-2022007202-A (MX)
Title: Cytokine-based bioactivatable drugs and methods of uses thereof.
Inventor: LI YUE-SHENG
IPC: A61K47/68
Filed: 2020-12-11
Abstract: The present disclosure provides a cytokine-based bioactivatable drug construct ("VitoKine") platform that aims to reduce systemic mechanism-based toxicities and lead to broader therapeutic utility for proteins and cytokines such as IL-15 and IL-2 for the treatment of cancer, autoimmune diseases, inflammatory diseases, viral infection, transplantation and various other disorders. The novel VitoKine constructs of the present invention comprise: 1) a tissue or disease site targeting moiety D1 domain ("D1"), 2) a bioactivatable moiety D2 domain ("D2"), and a concealing moiety D3 domain ("D3"). Importantly, because the "active moiety" of the VitoKine construct will remain inert until activated locally by proteases that are upregulated in diseased tissues, this will limit binding of the active moiety to the receptors or to the targets in the peripheral or on the cell-surface of non-diseased cells and tissue to prevent over-activation of the pathway and reduce undesirable "on-target" "off tissue" toxicities. Additionally, the inertness of the VitoKine active moiety prior to protease activation will significantly decrease the potential antigen or target sink, and thus, prolong the <i>in vivo</i> half-life and result in improved biodistribution, bioavailability and therapeutic efficacy.
Patent MX-2022008502-A (MX)
Title: Video decoding method and apparatus for obtaining quantization parameter, and video encoding method and apparatus for transmitting quantization parameter.
Inventor: PARK MINWOO
IPC: H04N19/124
Filed: 2021-01-08
Abstract: Provided is a video decoding method according to an embodiment provided in the present disclosure, the video decoding method comprising: obtaining, from a picture parameter set, a QP initial value and picture header QP difference value information to be applied to a current picture; when the picture header QP difference value information indicates that QP difference value information is present in a picture header of the current picture, obtaining, from the picture header, a first QP difference value for the current picture; determining a QP for a coding unit included in the current picture by using the QP initial value and the first QP difference value; obtaining transformation coefficients of the coding unit by performing inverse quantization on the coding unit by using the QP; and reconstructing the coding unit by using the transformation coefficients.
Patent MX-2022009731-A (MX)
Title: Self-cleaning plastics coating device.
Inventor: BAI MINGQUAN
IPC: B05C11/10
Filed: 2021-01-20
Abstract: The invention relates to a device for coating an object. The device comprises a static mixer having: a first inlet opening for a first plastics component; and a second inlet opening for a second plastics component; and a mixer outlet for a component mixture comprising both components. The device also comprises: a first connection for a reservoir for the first component, which is connected to the first inlet opening via a first supply line; and a second connection for a reservoir for the second component, which is connected to the second inlet opening by a second supply line. The device comprises two applicators (39, 40), specifically an applicator (39) and a further applicator (40) for the component mixture (8), and the plastics coating device (1) comprises a shuttle valve (32) which is designed to selectively connect the mixer outlet (5) of the mixer (2) to the applicator (39) or the further applicator (40).
Patent MX-PA00009567-A (MX)
Title: Application of phytase in feed having low content of phytate
Inventor: KIES ARIE KARST
IPC: A23K50/60
Filed: 2000-09-29
Abstract: The present invention relates to the use of the phytase enzyme in feeds having a low phytate content. The invention describes methods for feeding using a diet low in phytates supplemented with a phytase. Feeding an animal with a diet low in phytates comprises a substantial improvement of the animal's mineral state which results in improved zootechnical results with an improved growth rate and an improved feed conversion ratio. The invention also describes a feed, for animals, with low phytate content, which is supplemented with a phytase, as well as methods for the preparation of this feed.