baber/WOPTO huggingface dataset:
Patent CA-2924534-C (CA)
Title: Piercing member for container access device
Inventor: IVOSEVIC MILAN
IPC: A61J1/20
Filed: 2014-09-22
Granted: 2018-08-14
Abstract: A device for transferring fluids includes a piercing member having a distal end and a proximal end and defines a longitudinal fluid channel. An opening is positioned at the distal end of the piercing member with the opening in fluid communication with the longitudinal fluid channel. Further, a sleeve having a proximal end and a distal end includes an extended position where the sleeve surrounds the piercing member and a retracted position where the sleeve is retracted from the distal end of the piercing member. The sleeve defines an opening at the distal end of the sleeve with a gap defined between the retractable sleeve and the piercing member.
Patent CA-2926068-C (CA)
Title: Apparatus for generating electrical pulses and methods of using the same
Inventor: BEEBE STEPHEN J
IPC: A61N1/32
Filed: 2004-07-19
Granted: 2022-05-03
Abstract: A rnethod and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields ("nspErs"). The method includes circuitry for delivery of an agent into a cell via known methods followed by the application of nanosecond pulse electric fields to said cell in order to facilitate entry of the agent into the nucleus of the cell. In a preferred embodiment, the present invention is directed to a method of enhancing gene expression in a cell comprising the application of nanosecond pulse electric fields to said cell. An apparatus for generating long and short pulses according to the present invention is also provided. The apparatus includes a pulse generator capable of producing a first pulse having a long duration and low voltage amplitude and a second pulse having a short duration and high voltage amplitude.   A method and apparatus are prwded for der...tiring an agent into e cell through the application of nanosecond puise electric fields CnsPEF 'VI The method includes circuitry for flowery of an agent into a cis' vta known methods followed by the. application of nanoseoond pulse electric fields to said cell in order to tactitale entry ot the agent into the nucleus of the cetl in a preferred emoodiment the present invenbon is directed to a method of enhancing gene expression in a call comprising the application of nanosecond pulse electric yields to sard cetl An apparatus for generating long and short Pulsee &Coon:Mg to the present invention aiso pro.aded The apparatus includes a pulse generator capable of producing a first pulse having a long duration and low '.,ollage amplitude and a second pulse having a short tluteeliOn and high voltage amplitude
Patent CA-2927032-C (CA)
Title: Ameliorations et agencements pour valve de regulation de flux
Inventor: VARGAS FONSECA LUIZ HENRIQUE
IPC: F16K15/14
Filed: 2013-10-18
Granted: 2021-02-16
Abstract: La présente invention concerne des améliorations apportées à des valves du type "cartwheel", ainsi que des agencements respectifs incorporant lesdites valves, lesquelles comprennent une pièce de matériau élastomère sous la forme d'une roue, qui est fixée par l'anneau extérieur à l'enveloppe de la valve. L'invention comprend une prise centrale reliée par des tiges à l'anneau extérieur et normalement, lors d'une utilisation dans des enveloppes à deux voies seulement (entrée et sortie), ladite valve consiste en une valve unidirectionnelle. Lors d'une utilisation dans une enveloppe à trois voies ou plus, ladite valve peut assurer une fermeture étanche et le passage d'un flux de fluide des deux côtés de la valve, en alternance, selon le choix de conception de circulation des fluides.
Patent CA-2929708-C (CA)
Title: Analytique concernant des soins de patient
Inventor: STEINHAUER TOM
IPC: G16H20/17
Filed: 2014-12-05
Granted: 2023-08-15
Abstract: L'invention concerne un procédé, un système et un support lisible par ordinateur pour déterminer la conformité à des protocoles de soins de patient. Le système comprend une pompe à perfusion fournissant des informations de perfusion concernant un ou plusieurs médicaments administrés à un patient, ledit médicament comprenant des sédatifs et des analgésiques, et un processeur couplé pour pouvoir communiquer avec la pompe à perfusion et configuré pour déterminer des informations concernant ledit médicament qui est administré au patient sur la base des informations de perfusion par détermination d'un seuil de base pour ledit médicaments qui est administré au patient en fonction de la dose réelle dudit médicament administré au patient avant un instant courant, par détermination d'une quantité de dose dudit médicament actuellement en train d'être administré au patient et par comparaison du dosage dudit médicament actuellement en train d'être administré au seuil de base afin de déterminer un écart par rapport au seuil de base.
Patent CA-2933017-C (CA)
Inventor: ITO SABURO
IPC: G01N35/02
Filed: 2013-12-12
Granted: 2019-05-21
Abstract: A subject moving device includes: a base; a head section provided with vertically movable rods and moving along a prescribed movement path above the base; a first container section which stores a subject of movement; a second container section which receives the subject of movement; a tip stocking section which holds a plurality of tips in a state where the plurality of tips are attachable to the rods, the tips being attachable to and detachable from the rods and being configured to suction the subject of movement and discharge the suctioned subject of movement in accordance with vertical movements of the rods; a tip discarding section which collects the tips having finished the suction and the discharge of the subject of movement and having been detached from the rods; and a control section which controls the vertical movements of the rods and the movement operations of the head section.
Patent CA-2934915-C (CA)
Title: Aide auditive inserable dans le conduit auditif et systeme d'aide auditive
Inventor: DALHOFF ERNST
IPC: H04R25/00
Filed: 2014-12-18
Granted: 2021-08-31
Abstract: La présente invention concerne une aide auditive (26) qui peut être insérée dans le conduit auditif (12) d'un patient et qui comprend un actionneur (31) provoquant une stimulation mécanique de la membrane (14) du tympan. Ledit actionneur (31) comprend une surface interne (32) associée à la membrane (14) du tympan et une surface externe (42) associée au conduit auditif (12) et est conçu comme actionneur sous forme de disque plan dont la déformation stimule la membrane (14) du tympan. Sur l'actionneur (31) et à une certaine distance de la surface externe (42) est disposé un disque obturateur (43) qui limite avec la surface externe (42) une cavité (48) de préférence en forme de lentille.
Patent CA-2936898-C (CA)
Title: Surface de connexion d'une unite structurelle et methode de fabrication associee
Inventor: RICCOBENE THOMAS S
IPC: E04C1/00
Filed: 2016-07-22
Granted: 2019-03-12
Abstract: Une surface de connexion placée sur une face dune unité structurelle comprend un premier segment ayant un profil de surface tridimensionnel comprenant une pluralité de surfaces extérieures positives sétendant vers lextérieur le long dune direction normale depuis un plan et une pluralité de surfaces extérieures négatives sétendant vers lintérieur le long de la direction normale depuis le plan, dans laquelle au moins deux de la pluralité des surfaces extérieures positives sont séparées lune de lautre le long des directions verticales et horizontales et au moins deux de la pluralité des surfaces extérieures négatives sont séparées lune de lautre le long des directions verticales et horizontales. Un second segment est opposé au premier segment par rapport à un axe, dans lequel le second segment est une réflexion importante du premier segment à travers laxe, mais inversé le long de la direction normale.
Patent CA-2937999-C (CA)
Inventor: NAWATA HIDEKAZU
IPC: B60L50/16
Filed: 2015-01-26
Granted: 2018-02-20
Abstract: A hybrid vehicle includes an engine, a rotary electric machine, a filter and an ECU The engine includes an exhaust passage The rotary electric machine is a driving source of the vehicle The filter traps particulate matter flowing through the exhaust passage The ECU is configured to control the hybrid vehicle in any one of a plurality of control modes The plurality of control modes include a first control mode (CD) and a second control mode (CS) The number of opportunities for the engine to operate when the control mode is the second control mode (CS) is larger than the number of opportunities for the engine to operate when the control mode is the first control mode (CD) The ECU is configured to, when the filter is regenerated (S106), control the hybrid vehicle m the second control mode (CD)
Patent CA-2941634-C (CA)
Title: Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders
Inventor: MCCURDY CHRISTOPHER R
IPC: A61K31/497
Filed: 2015-03-03
Granted: 2023-04-18
Abstract: Described herein is a non-therapeutic method of detecting increased S1R  density at the site of nerve injury arising from neuropathic pain comprising S1R-PET imaging a tissue with an imaging agent to determine a non-invasive biomarker of nerve injury and inflammation wherein the imaging agent comprises at least one S1R selective radioligand selected from the general formula III':    wherein Ri is a radical of an optionally substituted piperazine, tetrahydropyridine, azepane or an tetrahydroisoquinoline in which the optional substituents are on the aromatic moiety or isoindoline-1,3-dione; R2,4,5 are each independently any one or combinations of hydrogen, cyano, nitro, acyl, alkyl, amido, azido, isothiocyanate, isocyanate, optionally substituted anilino, halogens, ethers, sulfonamides, thioacyl, nitro, aromatic, heterocyclic, olefinic, acetylene, deuterium, or tritium; Z is 0; "n" is 1 to 5 carbons; the moiety bridging Ri and N is a substituted alkylene; and X is tritium or Ci-C4 radiohaloalkyl; and stereoisomers, or pharmaceutically acceptable salts thereof.
Patent CA-2945918-C (CA)
Title: Method for producing nickel powder having low carbon concentration and low sulfur concentration
Inventor: OZAKI YOSHITOMO
IPC: B22F9/26
Filed: 2015-04-13
Granted: 2020-07-21
Abstract: Provided is a production method for reducing the content grades of sulfur and carbon, which are impurities contaminating a nickel powder, for the purpose of improving the quality of a nickel powder produced employing a complexing reduction process. A method for producing a nickel powder having a low carbon concentration and a low sulfur concentration, said method being characterized by comprising: carrying out a complexing treatment, wherein the complexing treatment comprises adding a complexing agent to an aqueous nickel sulfate solution to produce a solution containing nickel complex ions; blowing a hydrogen gas into the solution containing nickel complex ions while maintaining the solution at a liquid temperature of 150 to 250ºC in a pressure container to achieve hydrogen reduction, thereby producing a nickel powder; washing the nickel powder with water; and roasting the washed product under a nitrogen/hydrogen mixed gas atmosphere.
Patent CA-2946329-C (CA)
Title: Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies
Inventor: TAZI JAMAL
IPC: A61K31/166
Filed: 2009-01-12
Granted: 2020-09-01
Abstract: The present invention relates to a compound of one of the formulas I to XXI; a pharmaceutical composition comprising at least one such compound; and the use of at least one such compound in preparing a drug to treat, in a subject, a genetic disease resulting from at least one splicing anomaly.
Patent CA-2946795-C (CA)
Inventor: GOETSCH LILIANE
IPC: A61P35/00
Filed: 2015-04-27
Granted: 2021-03-30
Abstract: The present invention relates to an antibody, in particular a monoclonal antibody, capable of binding to IGF-1R, as well as the amino and nucleic acid sequences coding for said antibody. From one aspect, the invention relates to an antibody, or an antigen binding fragment thereof, capable of binding to IGF-1R and, by inducing internalization of IGF-1R, being internalized into the cell. The invention also comprises the use of said antibody as an addressing product or vehicle in conjugation with other anti-cancer compounds such as toxins, radio-elements or drugs, and the use of same for the treatment of certain cancers.
Patent CA-2955636-C (CA)
Title: Separation a capacite elevee de mineraux de minerai grossier a partir de dechets mineraux
Inventor: BAMBER ANDREW SHERLIKER
IPC: B07C5/34
Filed: 2015-07-21
Granted: 2022-08-09
Abstract: L'invention concerne des systèmes et des procédés de distribution de matériau minier à un réseau multimodal de différents types de capteurs et de classification et de tri du matériau minier sur la base des données collectées à partir du réseau multimodal de capteurs. Les réseaux de différents capteurs détectent le matériau minier et collectent des données qui sont ensuite utilisées ensemble pour identifier la composition du matériau et déterminer si le matériau doit être accepté ou rejeté à mesure qu'il passe par l'extrémité terminale du système de manipulation de matériau. Des organes de dérivation sont positionnés au niveau de l'extrémité terminale du système de manipulation de matériau et sont positionnés dans l'une ou l'autre d'une position d'acceptation ou de rejet sur la base des données recueillies et traitées pour identifier la composition du matériau minier.
Patent CA-2957022-C (CA)
Title: Extended range single-joint elevator
Inventor: ANGELLE JEREMY RICHARD
IPC: E21B19/06
Filed: 2015-08-04
Granted: 2020-10-27
Abstract: An elevator to manipulate a tubular segment includes an elevator body with a bore formed therethrough having an axis therein, the elevator body including a plurality of openings extending from an outer surface of the elevator body to the bore of the elevator body, and a base member coupled to a bottom surface of the elevator body, the base member having a guide portion that directs the tubular segment into the bore of the elevator body. The elevator also includes a plurality of slip assemblies disposed inside the plurality of openings and coupled to the elevator body, each of the plurality of slip assemblies including an actuator body coupled to the elevator body, a slip, the slip including an engagement surface disposed orthogonal to the axis of the bore of the elevator body that engages the tubular segment.
Patent CA-2957445-C (CA)
Title: System and method for connectivity mapping
Inventor: DYER KELLY NOEL
IPC: G06T7/11
Filed: 2014-10-17
Granted: 2017-10-31
Abstract: A processing system for and a method of segmenting a physiological image is provided. Once the physiological image is received, extrinsic data defining extrinsic regions is further received. Additionally, intrinsic data defining at least one intrinsic region, each intrinsic region corresponding to one extrinsic region is received. A primary modification is performed, where a shape and size of at least one extrinsic region having a corresponding intrinsic region is modified based on a shape and size of the corresponding intrinsic region, to form a modified extrinsic data. The physiological image is segmented into segmented regions based on the modified extrinsic data, each segmented region which has a corresponding intrinsic region representing a primary modification based on the corresponding intrinsic region.
Patent CA-2958228-C (CA)
Inventor: BRUCE IAN
IPC: G02B1/04
Filed: 2015-12-04
Granted: 2017-07-04
Abstract: A method for manufacturing a silicone hydrogel contact lens is described that comprises curing a polymerizable composition comprising at least one siloxane monomer and at least one hydrophilic vinyl-containing monomer in a contact lens mold comprising a molding surface having a coating comprising a hydrophilic polymer. The hydrophilic coating is not solubilized by the polymerizable composition during the curing step. The resulting polymeric lens body is removed from the mold, washed to remove any of the hydrophilic polymer that may have transferred from the mold surface to the lens during the curing or lens removal process, and packaged to provide a silicone hydrogel contact lens having a contact angle that is lower than what it would otherwise be had the lens been cured in the same contact lens mold lacking the hydrophilic coating.
Patent CA-2959916-C (CA)
Inventor: SHARMA SRIRAM
IPC: H04W8/18
Filed: 2017-03-03
Granted: 2019-07-02
Abstract: Une plate-forme de gestion sans frais (TFMP) comprend des méthodes et des systèmes pour ladministration des numéros, la gestion des clients, les services de gestion des appels, les services de SMS et le registre de texte, ainsi quun registre de services intelligents. Le TFMP peut permettre aux utilisateurs de recevoir, via une interface Web, une demande dactivation dun utilisateur, la demande comprenant au moins une référence de modèle denregistrement client et une indication du moment où un numéro de télécommunication sans frais associé à la demande doit être activé. La demande peut inclure au moins une donnée dadresse IP associée au numéro de télécommunication sans frais. Une interface utilisateur peut permettre dactiver un numéro sans frais et les utilisateurs peuvent accéder au TFMP pour créer et accéder à des modèles existants de modèles de routage dappels sans frais et utiliser un moteur darborescence de routage pour créer des arborescences de routage dappels personnalisées pour les numéros sans frais dintérêt pour lutilisateur.
Patent CA-2961972-C (CA)
Title: Osteointegrative composition for medical implants
Inventor: DIRKS ANTONIUS JOHANNES
IPC: A61L24/04
Filed: 2015-09-28
Granted: 2022-11-22
Abstract: The invention is directed to a composition, to a coating prepared from said composition, to an implant comprising a substrate that is coated with said coating, to a method for preparing an implant with said coating, and to a method for improving the bone apposition of an implant. The composition of the invention comprises (A) a compound comprising two or more epoxy groups; (B) an amine comprising one or more selected from a primary amine group and a secondary amine group; and (C) one or more compounds selected from general formula (1), (2), (3), and (4) wherein R1 is a group comprising a primary amine group, a secondary amine group, a carboxyl group, and/or a thiol group, and wherein the sum of the number of epoxy groups in component (A) and the number of primary amine groups in component (B) is equal to three or greater.
Patent CA-2969515-C (CA)
Inventor: AITKEN WILLIAM A H
IPC: E21B43/00
Filed: 2015-11-03
Granted: 2020-09-29
Abstract: An embodiment of a method of performing an energy industry operation includes: deploying a carrier in an earth formation, the carrier including a downhole component configured to perform the operation; performing the operation according to operational parameters; measuring a condition, the condition including at least one of a surface condition and a downhole condition, and generating measurement data representing the measured condition; tuning a simulation model of the operation based on the measurement data, the model being a mathematical model configured to estimate the condition based on the selected operational parameters; selecting a hypothetical adjustment to one or more selected operational parameters; applying the hypothetical adjustment to the simulation model to generate predicted conditions of the operation; and based on the predicted conditions representing an improvement to the operation, adjusting operational parameters according to the hypothetical adjustment.
Patent CA-2971844-C (CA)
Inventor: THOMPSON MATTHEW
IPC: A61F5/24
Filed: 2015-01-16
Granted: 2022-05-31
Abstract: La présente invention concerne des systèmes et des procédés de correction de déformation rachidienne qui surmontent les limites actuelles en utilisant une orthèse de torse dynamique à plusieurs segments (100) permettant le mouvement lorsqu'elle est portée. Dans les modes de réalisation de la présente invention, on utilise une série de segments accouplés élastiquement (102) qui se conforment à la circonférence du torse d'un patient. Des mécanismes d'accouplement élastique réglables (201) sont utilisés pour créer et modifier des forces et des moments qui sont appliqués au torse par le biais des segments (102). Ces mécanismes d'accouplement élastique (201) permettent en outre à chaque segment circonférentiel (102) de se déplacer par rapport aux autres segments, conférant ainsi une capacité dynamique à l'appareil orthopédique.
Patent CA-2972315-C (CA)
Title: Transporter systems, assemblies and associated methods for transporting tissue samples
Inventor: CRUM NATHAN
IPC: B01L3/00
Filed: 2016-01-26
Granted: 2021-09-14
Abstract: A tissue sample that has been removed from a subject can be evaluated. A transporter system for carrying a tissue sample includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process. A portable transporter system adapted to carry a tissue sample contacting a fixative, can include: a transport container including: a holding chamber; and a fixative; and a container lid including: a cassette holder operable to be coupled to the standard histology cassette and including a first seal; and a cassette receiver operable to be releasably coupled to said transport container and including a second seal, where the cassette holder and cassette receiver are operable to be attachably coupled to one another upon insertion of a standard histology cassette coupled to the cassette holder into the cassette receiver.
Patent CA-2975803-C (CA)
Inventor: MOHANTY AMAR K
IPC: C08L23/02
Filed: 2017-08-10
Granted: 2023-06-20
Abstract: Des polyoléfines renforcées et des méthodes utilisées pour produire ces polyoléfines renforcées en présence dun agent de remplissage biologique sont décrites. Ces matériaux peuvent substituer des polyoléfines thermoplastiques traditionnelles connues sous le nom de TPO ou de TPO à charge minérale. Des compositions en exemple comprennent une phase fondée sur des élastomères dalpha-oléfine et lutilisation dagents de remplissage biologiques. Lagent de remplissage biologique à utiliser peut être un matériau riche en carbone élémentaire. Lutilisation dadditifs est dusage normal pour ces compositions, car elles peuvent être liées à des promoteurs dadhésion, des absorbeurs UV, des stabilisants UV, des antioxydants, etc. Ces compositions offrent une faible densité remarquable par rapport aux compositions de TPO traditionnelles avec lajout de rendement de valeur biologique.
Patent CA-2980718-C (CA)
Inventor: CHIEN DAVID Y
IPC: G01N33/567
Filed: 2015-06-22
Granted: 2021-06-01
Abstract: Modified hepatitis C virus polypeptides are described. The polypeptides include the HCV NS4a domain and modified NS3 domain. The polypeptides retain conformational epitopes. HCV immunoassays including the polypeptides are also described.
Patent CA-3000214-C (CA)
Inventor: BIGI MARINUS A
IPC: C07F9/6574
Filed: 2016-09-07
Granted: 2023-08-29
Abstract: La présente invention concerne des procédés de production des compositions organophosporées ayant une faible teneur en acide ainsi que des procédés de retraitement de compositions organophosphorées partiellement dégradées qui contiennent des niveaux élevés d'acide phosphoreux. Dans un mode de réalisation, un procédé comprend : (a) la réception d'un composé organophosphite solide qui a été recristallisé ou trituré, le composé organophosphite solide comprenant de l'acide phosphoreux ; (b) la dissolution du composé organophosphite solide dans un solvant organique ; (c) le traitement de la solution avec un adsorbant faiblement basique ; et (d) la collecte de la solution d'organophosphite traitée, la teneur en acide de l'organophosphite après l'étape (d) étant de 30 ppm ou moins.