baber/WOPTO huggingface dataset:
Patent DE-69419919-T2 (DE)
Inventor: DEAN RICHARD
IPC: C07K7/08
Filed: 1994-05-25
Granted: 2000-04-20
Abstract: This invention relates to compositions that are radiolabeled scintigraphic imaging agents, comprising a polybasic compound covalently linked to a radiolabel binding moiety and the composition further comprising a polysulfated glycan. The invention also provides methods for producing and using such compositions. Specifically, the invention relates to compositions comprised of technetium-99m (Tc-99m) labeled scintigraphic imaging agents comprising a polybasic compound having at least 5 chemical functionalities that are basic at physiological pH and a radiolabel-binding moiety, the composition further comprising a polysulfated glycan, the composition being capable of specifically binding to inflammatory sites in vivo. Methods and kits for making such compositions, and methods for using such compositions to image sites of infection and inflammation in a mammalian body, are also provided.
Patent DE-69420137-T2 (DE)
Inventor: LANDON JOHN
IPC: A61P31/04
Filed: 1994-06-03
Granted: 1999-12-23
Abstract: A method of clotting blood comprising placing blood into a container and moving said container so that the blood platelets are damaged by contacting an inner surface of the container. <IMAGE>
Patent DE-69423802-T2 (DE)
Inventor: LAVIELLE GILBERT
IPC: A61K31/415
Filed: 1994-02-02
Granted: 2000-11-09
Abstract: The invention relates to the compounds of formula (I): <IMAGE>  in which:   R1 represents a hydrogen or halogen atom, an alkyl, alkoxy, cyano or aminocarbonyl group or any one of the following groups: <IMAGE>  -(CH2)m-NH-COR6, -(CH2)m-NH-SO2-R4, <IMAGE>  -(CH2)m-NH-CO-NHR4, <IMAGE>  -(CH2)m-SO2-NH-R4, -CH=CH-SO2-NH-R4, <IMAGE>  in which:     m is equal to 1, 2 or 3,   n is equal to 0, 1 or 2,   T represents a CO or SO2, R4 or R5, which are identical or different, represent a hydrogen atom or an alkyl or phenyl group,     R2 represents a hydrogen atom or an alkyl, phenyl or acyl group, R3 represents a hydrogen atom or an alkyl (optionally substituted by a hydroxyl or phenyl group) or alkoxycarbonyl group,   -X-Y= represents -N-C=, -N-N= or else <IMAGE>  represents -O-N=, to their enantiomers, diastereoisomers and epimers and to their addition salts with a pharmaceutically acceptable acid. Medicaments.
Patent DE-69426787-T2 (DE)
Inventor: RHOADS GEOFFREY B
IPC: G10L19/00
Filed: 1994-11-16
Granted: 2001-08-30
Abstract: A method of processing audio to convey auxiliary information therewith without audible evidence of audio alteration is provided, in which the audio is represented by digital data, and the auxiliary information comprises a data string having plural bit positions, each with a "1" or "0" value. The method comprises: receiving the plural bit auxiliary data; providing noise data; processing the plural bit auxiliary data and the noise data to yield intermediate data; and summing the intermediate data with the audio data to yield encoded audio; wherein the audio is repeatedly encoded from each of plural non-overlapping excerpts of the encoded audio.
Patent DE-69503900-T2 (DE)
Inventor: PETROCELLI PASQUALINO
IPC: A61M5/32
Filed: 1995-05-08
Granted: 1999-04-15
Abstract: PCT No. PCT/EP95/01732 Sec. 371 Date Dec. 2, 1996 Sec. 102(e) Date Dec. 2, 1996 PCT Filed May 8, 1995 PCT Pub. No. WO95/30445 PCT Pub. Date Nov. 16, 1995A disposable safety syringe in which the needle is automatically retracted after use to a position inside the tubular body of the syringe. The syringe, when retracted, cannot be reused; the needle-retraction means is not accessible to the operator, is not in contact with the substance to be injected, and at the end of the injection the needle is not axially advanced.
Patent DE-69515683-T2 (DE)
Inventor: EDERYD STEFAN
IPC: C04B41/88
Filed: 1995-12-27
Granted: 2000-07-06
Abstract: PCT No. PCT/SE95/01586 Sec. 371 Date Sep. 18, 1997 Sec. 102(e) Date Sep. 18, 1997 PCT Filed Dec. 27, 1995 PCT Pub. No. WO96/21051 PCT Pub. Date Jul. 11, 1996There is disclosed a method of coating cemented carbide inserts at least partly with a layer of at least one iron group metal. When inserts coated with such a layer are brazed to a tool holder, a joint with improved strength is obtained. According to the present method, one or more metal salts of at least one iron group metal containing organic groups are dissolved and complex bound in at least one polar solvent with at least one complex former comprising functional groups in the form of OH or NR3 (R=H or alkyl). A soluble carbon source is added to the solution which is subsequently at least partly applied to the cemented carbide inserts by dipping, spraying or painting. The inserts are dried and heat treated in an inert and/or reducing atmosphere. As a result, cemented carbide inserts are obtained at least partly coated with a layer of an iron group metal.
Patent DE-69522949-T2 (DE)
Inventor: ELFGREN ANDERS
IPC: A01B1/06
Filed: 1995-10-13
Granted: 2002-04-25
Abstract: A ground cultivating tool for being connected to a brush saw has the shape of a body (2) which is formed in one piece of sheet-metal, which body comprises on one hand a flat, circular basic part (9) with an aperture (13) for the connection to the brush saw, and on the other hand a cup-shaped part (10) protruding from the periphery of the basic part (9), in which cup-shaped part are provided three countersinks (11) which delimit a corresponding number of equidistantly separated working teeth (12, 12', 12''). The contour or delimiting edge of the individual countersink is on one hand arched as observed towards the envelope surface of the cup part, and on the other hand substantially rectilinear as observed in a planar projection perpendicularly to the plane of the basic part.
Patent DE-69528168-T2 (DE)
Inventor: THIVOLET CHARLES
IPC: A61P3/10
Filed: 1995-06-22
Granted: 2003-01-09
Abstract: IGF-I or an analogue thereof is administered to delay the clinical onset of diabetes, to reduce the occurrence of beta cell destruction in a subject having a high risk of developing diabetes, to provide a regulating effect on spleen T cells in a subject having a high risk of developing diabetes, or to reduce the likelihood of the occurrence of clinical diabetes in a subject having a high risk of developing diabetes.
Patent DE-69531170-T2 (DE)
Inventor: MEIKLE SCOTT
IPC: C23C16/46
Filed: 1995-11-30
Granted: 2004-05-06
Abstract: A non-planar storage capacitor comprises a non-planar first capacitor electrode (40), a dielectric layer (45) and a second capacitor electrode (50) formed by a tungsten nitride layer overlying the dielectric layer. Preferably the tungsten nitride layer comprises silicon. <IMAGE>
Patent DE-69532852-T2 (DE)
Inventor: BRADFUTE G
IPC: B32B27/32
Filed: 1995-05-19
Granted: 2005-04-28
Abstract: Film and sheet materials, and articles made therefrom, such as bags, pouches, trays, etc., comprise one or more layers of a thermoplastic, homogeneous alpha-olefin/vinyl aromatic copolymer, preferably an ethylene/styrene copolymer. The alpha-olefin/vinyl aromatic copolymer has properties which can can provide a desired performance characteristics such as impact resistance, printability, RF sealability, free shrink, optics, as well as many others. The homogeneous alpha-olefin-vinyl aromatic copolymer may be present in a mono-layer film, either alone or in a blend, or may be included in one or more layers of a multilayer film. Also included is a multilayer thermoformable article comprising a web having a film of such alpha-olefin/vinyl aromatic copolymers thereto. Finally, also included is an RF-sealable film comprising such copolymers.
Patent DE-69627211-T2 (DE)
Inventor: KRISTENSEN AXEL
IPC: B66F9/18
Filed: 1996-10-09
Granted: 2004-03-25
Abstract: PCT No. PCT/NO96/00235 Sec. 371 Date Mar. 31, 1998 Sec. 102(e) Date Mar. 31, 1998 PCT Filed Oct. 9, 1996 PCT Pub. No. WO97/13718 PCT Pub. Date Apr. 17, 1997A vacuum based lifter device is provided for displacement of an article. At least one suction plate or suction cup is designed for connection to and disconnection from a vacuum source. The suction plate or suction cup is secured to equipment in order to be able to move it together with or relative to the article which is to be displaced. The device has a pallet-like structure into which fork members mounted on a fork-lift truck can be inserted. Parts of the structure define a vacuum chamber, a vacuum source having an electrically driven vacuum pump provided on the pallet-like structure and pneumatically connected to the vacuum chamber, and a mechanically or electrically controllable stop and release valve. The release valve is pneumatically coupled between the vacuum chamber and the suction plate or suction cup.
Patent DE-69635081-T2 (DE)
Inventor: CERNY RADIM
IPC: C12P21/02
Filed: 1996-06-26
Granted: 2006-06-01
Abstract: The invention relates to novel nucleic acid fragments encoding polypeptides which are capable of mediating contact between enamel and cell surface. The invention also relates to expression vectors containing the nucleic acid fragments according to the invention for production of the protein, organisms containing said expression vector, methods for producing the polypeptide, compositions comprising the polypeptides, antibodies or antibody fragments recognizing the polypeptides, and methods for treating various hard tissue diseases or disorders.
Patent DE-69702227-T2 (DE)
Inventor: ZAKIKHANI MOHSEN
IPC: C08G59/40
Filed: 1997-04-25
Granted: 2000-12-21
Abstract: A polymer composition including phosphorus substituents which comprises:   (a) a phosphono - substituted carboxylic acid or an ester of such acid; and   (b) a mono- or polyfunctional entity polymerisable with (a).   Substances suitable for use as (a) are aliphatic or aromatic phosphono-substituted dicarboxylic acids or esters thereof. Substances suitable for use as (b) are polyhydric alcohols, aliphatic mononuclear or polynuclear aromatic polycarboxylic acids or esters or anhydrides thereof. Also suitable for use as (b) are aliphatic or aromatic polyamines and aliphatic or aromatic polyisocyanates or poly-epoxides.
Patent DE-69703143-T2 (DE)
Inventor: KOIKE HIROKI
IPC: C07D471/04
Filed: 1997-08-08
Granted: 2001-03-22
Abstract: This invention provides a compound of the formula: <CHEM>  and its pharmaceutically acceptable salts, wherein Ar<1> is selected from groups of the following formulae: <CHEM>  wherein,     R<1> and R<2> are independently hydrogen or C1-C6 alkyl;   W is (CH2)n wherein n is from 1 to 3, or -CH=CH-;   X is C1-C6 alkoxy or halo C1-C6 alkoxy; and   Ar<2> is phenyl optionally substituted by halogen atom.   These compounds are useful in the treatment of a gastrointestinal disorder, a central nervous system (CNS) disorder, an inflammatory disease, emesis, urinary incontinence, pain, migraine, sunburn, angiogenesis, diseases, disorders and adverse conditions caused by Helicobacter pylori, or the like in a mammalian subject, especially humans.
Patent DE-69715048-T2 (DE)
Inventor: SELTMAN JOACHIM W
IPC: D21B1/02
Filed: 1997-01-31
Granted: 2003-04-17
Abstract: A method and an arrangement for obtaining wood in which the tracheids have less ability to bind to each other. The end surface of the wood is irradiated with pulsed laser light of such strength, and with such a number of pulses, that lignin-related cellulose and hemicellulose bonds break up along the light-conducting middle lamella to a depth which is sufficient to ensure that reduction of the wood (to paper pulp) via mechanical processes can be done more quickly, more gently and with greater efficiency.
Patent DE-69724656-T2 (DE)
Inventor: VAN DE MOORTELE IVO
IPC: B01J49/80
Filed: 1997-07-29
Granted: 2004-07-01
Abstract: A water treatment device wherein the water during treating is brought into contact with a treatment medium (29), whereby this treatment medium (29), either by means of a regeneration medium (42) or not, is regenerated regularly and whereby, a regulator (59) is used which is provided, with a hydraulically driven first monitoring mechanism (24) with which the water consumption can be controlled and the start of the regeneration cycle can be ordered, and with a hydraulically driven second monitoring mechanism (25) with which the regeneration cycle is controlled and characterized in that both monitoring mechanisms (24-25) are driven by means of the same volumeter (23).
Patent DE-69725308-T2 (DE)
Inventor: VAN OORT MICHIEL
IPC: A61K9/00
Filed: 1997-03-25
Granted: 2004-08-05
Abstract: A process for dispersing medicament from an inhalator device which contains medicament particles. The process involves (i) providing an inhalator which contains at least one dose of medicament particles comprising spherical hollow particulates of respirable particle size suitable for deposition in a human being's lungs, and (ii) removing the spherical hollow particulates from the inhalator.
Patent DE-69729736-T2 (DE)
Inventor: GARIN LIONEL
IPC: G01S1/00
Filed: 1997-09-19
Granted: 2005-07-21
Abstract: A receiver of a radio frequency signal having a pseudo-random noise (PRN) code modulated on a carrier, and techniques of processing such a signal that are especially adapted for ranging applications. Such an application is in a global positioning system (GPS or GLONASS) receiver. Both of the receiver DLL code and PLL carrier loops include a loop component that senses an error in its main loop caused by the presence of a multipath signal. The main loop is continuously adjusted by this sensed error, thereby causing the loop to track more precisely and minimize the effect of the multipath signal. The result is a more accurate range measurement.
Patent DE-69732855-T2 (DE)
Inventor: DEMERS ROBERT
IPC: B01J19/00
Filed: 1997-10-10
Granted: 2006-04-13
Abstract: The present invention provides a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions. The distribution system can comprise an alpha reservoir and a beta reservoir, a first set of parallel and adjacent first and second feeder channels and a second set of parallel and adjacent third and fourth feeder channels which are offset from the first and second feeder channels, wherein (a) the first and third feeder channels are connected to the alpha reservoir via a first connector channel that is situated above or below the second and fourth feeder channels and are independent of the beta reservoir and (b) the second and fourth feeder channels are connected to the beta reservoir via a second connector channel that is situated above or below the first and third feeder channels and are independent of the alpha reservoir. The distribution system is preferably a microscale distribution system. Various particular mechanisms for controlling flow into a liquid distribution system are described.
Patent DE-69736083-T2 (DE)
Inventor: WALDREP CLIFFORD J
IPC: A61K9/72
Filed: 1997-07-02
Granted: 2006-12-28
Abstract: The present invention provides a high dose pharmaceutical liposome aerosol composition comprising about 12-30 mg/ml of a pharmaceutical compound, and about 130-375 mg of a phospholipid/ml starting reservoir concentration. Specifically, the present invention is drawn to anti-inflammatory glucocorticoids, immunosuppressive compounds, anti-fungal compounds, antibiotic compounds, anti-viral compounds, and anti-cancer compounds delivered via a high dose liposome aerosol composition in a phospholipid. More specifically, the invention provides a high dose cyclosporin A liposome aerosol composition comprising up to about 30 mg/ml cyclosporin A in up to about 225 mg of a phospholipid/ml starting reservoir concentration. Also provided is a high dose budesonide-liposome aerosol composition comprising up to about 15 mg/ml budesonide in up to about 225 mg of a phospholipid/ml starting reservoir concentration.
Patent DE-69800804-T2 (DE)
Inventor: MAULEON CASELLAS DAVID
IPC: A61K47/32
Filed: 1998-06-04
Granted: 2001-09-13
Abstract: The present invention relates to a process for the preparation of a semisolid pharmaceutical formulation (gel or cream) containing dexketoprofen trometamol and different amines as neutralizing agents, for the topical treatment of inflammatory processes in humans. The pharmaceutical formulations object of the present invention show advantages deriving from their high storage stability without noticeable changes in the appearance of the product in time, as well as from their lower allergenic and photoallergenic activities.
Patent DE-69810430-T2 (DE)
Inventor: LODGE ANTHONY-PROMOTION CONSUL
IPC: B44F1/10
Filed: 1998-06-17
Granted: 2003-09-25
Abstract: A method of decorating an article such as tableware comprises mixing a thermochromic ink with a transparent lacquer, applying the mixture on to part or all of the surface of an article, once the mixture is set, applying a second layer of dishwasher proof transparent lacquer. The proportion of ink in the mixture may be 5-25%. A decoration can be provided on the article beneath the mixture so that it is visible when the thermochromic ink is at least translucent.
Patent DE-69810785-T2 (DE)
Inventor: DERBYSHIRE E
IPC: G01N23/227
Filed: 1998-02-03
Granted: 2003-10-23
Abstract: A detection device for analyzing charged particles. The charged particle analyzer comprises a source of charged particles and a charged particle detector spaced from the source and immersed within the source in an ionizable gas. The detector comprises at least one pair of electrodes, characterized in that the electrodes of the pair are spaced apart by a distance that is substantialy less than the spacing between the source and detector. The electrodes of the pair are maintained at different potentials, and the source is maintained at a potential different from the potentials of the electrodes. The potentials are selected such that charged particles emitted by the source are attracted from the source toward each of the pair of electrodes and such that charged particles adjacent the detector are accelerated to energies sufficient to ionize the gas.
Patent DE-69810799-T2 (DE)
Inventor: HARVEY ROBERT ALAN
IPC: B41J2/055
Filed: 1998-10-09
Granted: 2003-10-23
Abstract: A piezoelectric printhead or other droplet deposition apparatus has parallel liquid containing channels defined by a base and displaceable walls, and covered by a cover number. The channels each have at least one nozzle for ejecting droplets. Each nozzle may be disposed in the base, the cover then having two ink supply parts spaced lengthwise of each channel on opposite sides of the nozzle. Alternatively two longitudinally spaced nozzles may be provided in the base of each channel. The cover may have a conductive track corrected to wall-displacing electrodes, the points of connection being outside the channels. <IMAGE>
Patent DE-69810906-T2 (DE)
Inventor: MORETTI PIERO
IPC: A61K31/135
Filed: 1998-01-28
Granted: 2003-11-13
Abstract: S(-)-amino-6-fluoro-7-methoxytetraline, a process for its preparation and pharmaceutical compositions containing same, active in preventing and treating septic shock, are disclosed.
Patent DE-69820464-T2 (DE)
Inventor: KOURTIS HRAKLIS
IPC: A61B17/64
Filed: 1998-11-23
Granted: 2004-10-07
Abstract: The invention belongs to the field of Orthopedic Surgery, Traumatology and Distraction Osteogenesis and consists of a telescopic unit used in an external fixation system, as well as of an external fixation system with telescopic units and has a wide range of applications in all therapeutic surgical practices which today use systems of external fixation. The telescopic mechanism carried by each unit of the system, in combination with the way the telescopic units are attached to the rod of the system, allow for each held pin the choice of five degrees of free spatial movement and, indeed, separately and independently of the rest of the held pins. Furthermore, it offers a wide range of choices to the user, with regard to the number of the telescopic units and the combination of the components he will choose to place on the rod, in order to achieve the best, in his opinion, stabilisation of the bone to be restored, while, for the same reason, he may incorporate in the system a second rod with the same wide range of choice, number of telescopic units and combination of components he will choose to place, which he will attach to the first rod. <IMAGE>
Patent DE-69828284-T2 (DE)
Inventor: OKA HIROKO
IPC: C07D471/04
Filed: 1998-06-30
Granted: 2005-12-08
Abstract: A novel naphthyridine compound represented by the general formula (1): <CHEM> wherein R<1>, R<2> and R<3> are independently a hydrogen atom, a lower alkyl group or the like, or R<1> and R<2>, or R<2> and R<3>, when taken together, form a cyclic group; each of X and Y is a methylene or ethylene group; Z is a phenyl group, a substituted phenyl group or the like; A is a hydrogen atom, a lower alkyl group or the like; and G is an acyl group, shows antagonism for tachykinin receptors and is useful as a prophylactic or therapeutic agent for diseases for which the tachykinin receptors are considered to be responsible. A specific example of such a compound is 2-Ä(-)-4-(N-benzoyl-N-methyl)amino-3-(3,4-dichlorophenyl)butylÜ-10-ace tylamino-1,2,3,4-tetrahydro-benzoÄbÜÄ1,6Ünaphthyridine.
Patent DE-69829198-T2 (DE)
Inventor: LASKEY ALFRED
IPC: G01N33/15
Filed: 1998-10-21
Granted: 2006-01-12
Abstract: Methods tor determining cell growth abnormalities, particularly cancerous or pre-cancerous cells, are described in which polypeptides involved in the preinitiation complex of DNA replication are detected. Target polypeptides include CDC6, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Typically antibodies detecting these proteins are used in screening assays on tissue sections or smears. The detection of RNA encoding these proteins is also described. The application is particularly concerned with cervical neoplasia's but also describes screening for growth abnormalities of breast, colon, lung, bladder, skin, larynx, oesophagus, bronchus, lymph nodes and urinary tract tissue.
Patent DE-69833394-T2 (DE)
Inventor: MILOSLAVSKY ALEC
IPC: H04Q3/66
Filed: 1998-09-09
Granted: 2006-10-12
Abstract: An Internet Protocol Network Telephony call-routing system is disclosed comprising a routing-processor (223) adapted for receiving and forwarding calls and a router (342) associated with the routing processor (223) and having different selectable routing protocols associated with different levels of system condition or performance. A system monitor (352) determines system condition and performance, including system degradation and cause of degradation. The router (342) selects a routing protocol based on a change in system condition or performance to a new level, according to the appropriate protocols associated with the new level of system condition or performance, and on a basis of relative insusceptibility to the causes of system degradation. <IMAGE>
Patent DE-69835967-T2 (DE)
Inventor: MATKOVICH VLADO IVAN
IPC: A61M39/02
Filed: 1998-05-08
Granted: 2007-09-20
Abstract: A connector assembly and a fluid system or device comprises a connector assembly which includes first and second fittings, each fitting having an aperture, and a stem disposed in the aperture of the first fitting. In various embodiments of the invention, the connector assembly may further comprise a socket cooperatively arranged with one of the first and second fittings, at least one resilient sealing member, a sealing layer joined to the socket or covering the resilient sealing member, and/or a deformable locking device. A method for making a connection includes mating a first fitting having an aperture and a second fitting having an aperture without fluid within the first and second fittings, establishing a fluid flowpath through the first and second fittings by advancing a stem having a head through the aperture of the first fitting into the aperture of the second fitting, and establishing fluid flow through the first and second fittings by opening a fluid blocking mechanism.