baber/WOPTO huggingface dataset:
Patent NZ-586759-A (NZ)
Title: Aqueous-alcoholic, single-phase transcutaneous pharmaceutical compositions containing a steroid hormone
Inventor: LEVERD ELIE
IPC: A61K31/56
Filed: 2008-12-04
Abstract: The disclosure relates to a transcutaneous pharmaceutical composition of monophasic hydroalcoholic type comprising: more than 30% of one or more short chain (C1-C4) alcohols, a steroidal hormone (such as testosterone), at least one fatty acid ester and propylene glycol as a penetration agent, wherein the concentration of said fatty acid ester and propylene glycol as penetration agent with a concentration of from 0.5% to 10% (m/m) of the composition, and an apolar solvent (such as N,N-di-ethyl-m-toluamide, commonly referred as DEET) soluble in the hydroalcoholic phase.
Patent NZ-591223-A (NZ)
Title: Viscosity reduction via highly propogating ultrasonic energy
Inventor: BATES DARREN M
IPC: A23L5/30
Filed: 2009-07-29
Abstract: 591223 Disclosed is a method for reducing the viscosity of a product by applying highly propagating ultrasonic energy to said product, the method comprising: contacting at least a portion of said product with an highly propagating ultrasonic energy emitting assembly; and emitting highly propagating ultrasonic energy from the assembly into the product thereby reducing the viscosity of the product; Also disclosed is an apparatus for reducing the viscosity of a product.
Patent NZ-593778-A (NZ)
Title: Method for selectively deploying an assessment instrument to a selected subset of a plurality of recipients
Inventor: YASKIN DAIVD
IPC: G06Q10/00
Filed: 2006-04-12
Abstract: A method for selectively deploying an assessment instrument to a selected subset of a plurality of recipients is disclosed. In this method a first input defining the assessment instrument is received and second input defining criteria is received by a computer. The criteria relates to a plurality of identifying attributes associated, respectively, with each of the plurality of recipients. The selected subset based on those of the plurality of recipients having associated identifying attributes matching the criteria is identified and the assessment instrument is deployed to the selected subset. Also disclosed is a method for selectively deploying an assessment instrument to a selected subset of a plurality of recipients of an institution comprising receiving, by a computer, first input defining a criteria, the criteria related to a plurality of identifying attributes associated, respectively, with each of the plurality of recipients; forwarding the first input to a first separate computer-based system of the institution; in response, receiving identification of members of the selected subset; and deploying the assessment instrument to the selected subset.
Patent NZ-598887-A (NZ)
Title: A method for preparing a multi-block copolymer
Inventor: BREITENKAMP
IPC: C08F283/06
Filed: 2006-01-04
Abstract: ABSTRACT - 598887 Disclosed is a hybrid block copolymer comprising a poly(amino acid) portion of formula (II) wherein the poly(amino acid) portion contains multiple amino acids, wherein the variables are as defined in the specification. The disclosure also relates to a method for preparing a multi-block copolymer of formula (II), wherein said method comprises the steps of: (a) providing a compound of formula (I); (b) polymerizing a first cyclic amino acid monomer onto the amine salt terminal end of formula (I), wherein said first cyclic amino acid monomer comprises Rx; and (c) optionally polymerizing a second cyclic amino acid monomer, comprising Ry, onto the living polymer end, wherein said second cyclic amino acid monomer is different from said first cyclic amino acid monomer.
Patent NZ-599006-A (NZ)
Title: Fluoro-substituted 3,5-dicyano-4-(1h-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof
Inventor: VAKALOPOULOS ALEXANDROS
IPC: A61K31/416
Filed: 2010-10-01
Abstract: Disclosed herein is a compound of formula (I) wherein is R1 hydrogen, fluoro, methyl or ethyl, R2 is methyl, difluoromethyl or trifluoromethyl, R3 is hydrogen or fluoro, R4 is hydrogen, methyl or ethyl, and is hydrogen or methyl; a salt thereof of the formula (I-A) wherein Q+ is an alkali metal cation or a quaternary ammonium cation; a process for the preparation thereof and the use thereof in the treatment of cancer. The process is characterised in that an indazolyl aldehyde of formula (II) is reacted with a ketonitrile of formula (II) in the presence of an acid, acid/base combination and/or dehydrating agent to give a compound of formula (IV) which is then condensed either with an enaminonitrile of formula (V) in the presence of a base to give a compound of formula (I-C) or dihydropyridine salt formation by treatment with an agent of formula (VIII) to yield the 1,4-dihydropyridinide salt of formula (I-A). Exemplary compounds include: rac-2-Methyl-4-(3-methyl-1H-indazol-5-yl)-6-(trifluoromethyl)-1,4-dihydropyridine-3,5-dicarbonitrile; (4R)-2-(difluoromethyl)-4-( 6-fluoro-3-methyl-1H-indazol-5-yl)-6-methyl-1,4-dihydropyridine-3,5-dicarbonitrile; and 2,6-bis( difluoromethyl)-4-(6-fluoro-3-methyl-1H-indazol-5-yl)-1,4-dihydropyridine-3,5-dicarbonitrile.
Patent NZ-599284-A (NZ)
Title: Combinations of a specific hcv ns5a inhibitor and an hcv ns3 protease inhibitor
Inventor: VOSS STACEY A
IPC: A61K31/4178
Filed: 2010-10-08
Abstract: ABSTRACT - 599284 The disclosure relates to a composition comprising a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, and a therapeutically effective amount of a compound of formula (II) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, wherein the compound of formula (I) and the compound of formula (II) are present in the composition in proportions that are synergistic in treating an HCV infection. The composition may further comprise one or two additional compounds having anti-HCV activity, such as an interferon or a ribavirin.
Patent NZ-599548-A (NZ)
Title: Biodegradable implantable medical devices formed from super - pure magnesium-based material
Inventor: PAPIROV IGOR ISAKOVICH
IPC: A61L27/04
Filed: 2010-10-29
Abstract: 599548 A medical biodegradable endoprosthesis body, formed at least partly from a constructional material of an alloy comprising super-pure magnesium and one or more super-pure alloying elements?wherein the super-pure magnesium has a purity of not less than 99.998 % (w/w) and contains a level of impurity of iron?cobalt?nickel and copper?each equal to or less than 0.0002 % (w/w) of each said impurity; one or more super-pure alloying elements each has a purity not lower than 99.99 % (w/w) and each contains impurity of iron?cobalt?nickel and copper at a level of no more than 0.00025 % (w/w) of each said impurity?wherein the one or more super pure alloying elements is chosen from scandium?yttrium?indium?gallium or one or more rare earth elements. Preferably wherein the content of super-pure scandium in the alloy is between 0.1 and 15% (w/w) or the super-pure alloying element is yttrium?indium?gallium or one or more rare earth elements and the content in the alloy is between 0.1 and 5% (w/w). Preferably wherein the construction material has a grain size of less than 5 microns. Specifically wherein the endoprosthesis is a medical stent, staple, bolt, plate, coil, catheter, screw, tubular mesh, wire, spiral or X-ray marker.
Patent NZ-600207-A (NZ)
Title: Substituted 4-aminocyclohexane derivatives
Inventor: NOLTE BERT
IPC: A61K31/137
Filed: 2009-03-25
Abstract: ABSTRACT - 600207 The disclosure relates to 4-aminocyclohexane derivatives represented by general formula (I), wherein the variables are as defined in the specification. Examples of the compound of formula (I) include: 1-(imino(1-methyl-1H-indol-2-yl)methyl)-N1,N1,N4,N4-tetramethyl-4-phenylcyclohexane-1,4- diamine bis(2-hydroxypropane-1,2,3-tricarboxylate); 1,4-bis(dimethylamino)-4-phenylcyclohexyl)(1-methyl-1H-indol-2-yl)methanone; N1,N1,N4,N4-tetramethyl-1,4-diphenylcyclohexane-1,4-diamine; The compounds of formula (I) in the form of a single stereoisomer or mixture thereof, the free compounds and/or their physiologically acceptable salts are used for the treatment of pain.
Patent NZ-600693-A (NZ)
Title: Composition and method for reducing friction in internal combustion engines
Inventor: ALEXANDER BRUCE D
IPC: C10L1/22
Filed: 2010-12-15
Abstract: 600693 A fuel composition comprising a combustible fuel, an effective friction reducing amount of at least one C6 to C30 aliphatic amine, and a detergent package is disclosed, as well as a method of reducing the amount of friction in an internal combustion engine by adding the fuel composition to the engine.
Patent NZ-601165-A (NZ)
Title: A lock
Inventor: TEREI ANARU
IPC: E05B41/00
Filed: 2012-07-09
Abstract: 601165 Disclosed is a lock comprising: a bolt which is movable between a latching position and an unlatching position, a mover component, which is movable between a first position and a second position, and which is operatively associated with the bolt such that the bolt moves from the latching position to the unlatching position when the mover component moves from the first position to the second position, one or more locking components which is/are moveable to a locking position in which the bolt is prevented from moving from the latching position to the unlatching position by the one or more locking components, and an unlocking position in which the locking component(s) do(es) not prevent the bolt from moving from the latching position to the unlatching position, wherein the mover component is unable to move from the first position to the second position when the locking component(s) is/are in the locking position, and a first operating component and a second operating component, both of which are operable to move the mover component from the first position to the second position when the locking component(s) is/are in the unlocking position, and wherein one or other of the operating components, selectably, is linked with the mover component in a manner such that movement of that operating component is restricted to movement corresponding to movement of the mover component while the other operating component is moveable relative to the mover component and is operable to cause the locking component(s) to move between the locking position and the unlocking position.
Patent NZ-604078-A (NZ)
Title: Safety device for a pre-filled syringe and injection device
Inventor: ROBERTS GARETH
IPC: A61M5/32
Filed: 2011-06-21
Abstract: 604078 A safety device (1) for a pre-filled syringe comprises a hollow support body (1.2) to retain the pre-filled syringe therein, a hollow needle shield (1.1) that is slidable relative to the support body and guiding means for guiding the movement of the needle shield relative to the support body. The guiding means comprise a deflectable flexible arm (1.1.4), a guide pin (1.1.3) and a guide track (1.2.2). The deflectable flexible arm extends essentially parallel to a central axis (A) of the safety device. The guide pin extends radial from the flexible arm. The guide track guides the guide pin within and along the guide track when the needle shield is slid relative to the support body.
Patent NZ-605804-A (NZ)
Title: New aminopyrazoloquinazolines
Inventor: FALLA TIMOTHY J
IPC: A61K8/44
Filed: 2011-07-22
Abstract: 605804 Disclosed is the use of a compound of the formula:
Patent NZ-607666-A (NZ)
Title: A pipe support
Inventor: HAYNES ANDREW LEO
IPC: F16L3/137
Filed: 2012-02-27
Abstract: A clip for attaching a pipe to a support surface is disclosed. The clip has a longitudinally extensile region (1) which encircles the pipe to be secured, and a first (2) and second (3) end region. When the first and second end regions are in an open position relative to one another (as shown) a pipe can be positioned within the extensile or linking region. When in the closed position relative to one another the extensile region of the support is brought into firm contact around the outer surface of the pipe. This “firm contact” is maintained by inserting a fastener through a coaxial channel in both end regions. The extensile region may be of a concertina or serpentine type configuration; allowing it to conform to the diameter of the pipe in a resilient manor.
Patent NZ-609279-A (NZ)
Title: Heat blanket at high density power
Inventor: GIORGIO CACCIA
IPC: H05B3/36
Filed: 2013-04-10
Abstract: 609279 Disclosed is a heat blanket. The blanket includes a power supply control unit (300) and an operating unit (400) that includes a foldable sheet and a heating element (100) distributed within the sheet. The power supply control unit (300) is electrically connectable on one side to an alternating current electric supply and on the other side it is electrically connectable, through an interconnection cable comprising two conductors (510, 520) only, to the operating unit (400). The power supply control unit (300) contains means for supplying the heating element (100) with alternating voltage having first and second polarity managed in a separate way. The first polarity is managed by an electro-mechanical switch (202) connected in series to a diode type semiconductor (201), while the second polarity is managed by a switching element (203) controlled by an electronic circuit (206).
Patent NZ-609819-A (NZ)
Title: Gas manifold bracket for gas grill
Inventor: BEHNKE PAUL ROBERT
IPC: F16L3/02
Filed: 2013-04-24
Abstract: Gas grill (10) having a fire box (14), including a front wall (22), a back wall and two side walls, a support frame (12) for supporting the fire box. A mounting bracket (40) for supporting a gas distribution manifold (35), comprising: a manifold support portion (41) for supporting the gas distribution manifold; a fire box attachment portion (42) for securing said bracket to the front wall of said fire box, wherein said fire box attachment portion is substantially parallel to the front wall of said fire box; and, a frame attachment portion for securing said bracket to said support frame.
Patent NZ-610567-A (NZ)
Title: Rectal drain appliance
Inventor: GREGORY CHRISTOPHER
IPC: A61F5/44
Filed: 2009-05-01
Abstract: А rectal drainage appliance (10) is disclosed. The appliance has а tubular element (12) defining а drain passage with an inflatable balloon (20) at а distal end for insertion into the rectum. An auxiliary lumen (24) communicates with the inflatable balloon (20) and is coupled to a pressure indicator (34) for indicating а pressure level within the balloon (20). The pressure indicator (34) comprises а first mechanical element (36) configured to flip between first and second physical states depending on the sensed pressure.
Patent NZ-614325-A (NZ)
Title: Variants of human gdnf
Inventor: LU JIRONG
IPC: C07K14/475
Filed: 2012-04-03
Abstract: Disclosed is a human GDNF variant comprising the amino acid sequence of SEQ ID NO:23 and its use in treating Parkinson’s disease, wherein the sequence is as defined in the specification.
Patent NZ-624374-A (NZ)
Title: Screw fastener
Inventor: D’SILVA BRIAN P
IPC: F16B23/00
Filed: 2012-10-22
Abstract: A screw having a driving head (2) of polygonal form that engages a socket with a wedging action is disclosed. The head is tapered so as to mate with a wedging fit with a drive socket of corresponding form to prevent wobble of the screw during application. The matching socket is also disclosed.
Patent NZ-629309-A (NZ)
Title: Tumour necrosis factor receptor fusion proteins and methods of using the same
Inventor: GEARING DAVID
IPC: C07K14/435
Filed: 2013-02-22
Abstract: Disclosed is an isolated polypeptide comprising the extracellular domain of canine tumour necrosis factor (TNF) receptor p80 polypeptide, or a TNF binding fragment thereof, wherein the extracellular domain comprises amino acid residues 23 to 260 of SEQ ID NO:14 or a sequence having at least 95% sequence identity thereto. Further disclosed is a chimeric fusion polypeptide comprising said polypeptide.
Patent NZ-705034-A (NZ)
Title: Crossbar t-slot infill
Inventor: CONDON DAVE
IPC: B60R9/04
Filed: 2013-07-30
Abstract: An infill device may include a lower portion pressing against a floor portion of a cavity of a slotted crossbar of a vehicle rack, and an upper portion pressing upward on first and second opposing lips of a longitudinal opening to the cavity. The infill is operable between a flush position corresponding to the upper portion substantially filling the opening, and a compressed position corresponding to the upper portion moving away from the opposing lips and closer to the floor portion to allow a retention device of a cargo-specific rack accessory to enter the channel and clamp the opposing lips.
Patent NZ-713179-A (NZ)
Title: Methods and compositions for rapid multiplex amplification of str loci
Inventor: SCHUMM JAMES W
IPC: C12Q1/68
Filed: 2012-05-11
Abstract: A method of multiplex amplification of STR loci to generate an STR profile from a sample containing nucleic acids, comprising: (a) contacting in solution said sample with at least seven different primer pairs for at least seven STR loci selected from the group consisting of Amelogenin, D3S1358, D19S433, D2S1338, D22S1045, Penta B, D16S539, D5S818, D18S51, D13S317, D7S820, D1S1656, TPOX, D10S1248, CSF1PO, D2S441, Penta D, Penta E, THO1, vWA, D21S11, D12S391, Penta C, D8S1179, FGA and SE33, and is labelled with a different fluorescent dye, and wherein at least seven different fluorescent dyes are used to label the primers; (b) simultaneously amplifying by polymerase chain reaction (PCR) in one reaction chamber using said at least seven primer pairs to produce at least seven amplified nucleic acid products; and (c) detecting said nucleic acid products by laser-induced fluorescence.
Patent NZ-715144-A (NZ)
Title: Insulin glargine/lixisenatide fixed ratio formulation
Inventor: SOUHAMI ELISABETH
IPC: A61K38/28
Filed: 2014-06-13
Abstract: The present invention refers to a pharmaceutical composition comprising (a) lixisenatide or/and a pharmaceutically acceptable salt thereof, and (b) insulin glargine or/and a pharmaceutically acceptable salt thereof, wherein the compound (b) and compound (a) are present in a fixed ratio. A particular embodiment of the invention is directed at the use of compounds (a) and (b) in the manufacture of a medicament for treating diabetes mellitus type 2 in a subject as add-on to treatment with metformin and/or a pharmaceutically acceptable salt thereof, where compound (b) is present in a concentration of 100 U/ml, and compound (a) is present in a concentration of 50 µg/ml.
Patent NZ-721985-A (NZ)
Title: Methods and compositions for the targeted modification of a genome
Inventor: KUNO JUNKO
IPC: C12N15/85
Filed: 2014-10-15
Abstract: Currently the use of rats in modelling human diseases has been limited compared to mice, due in part to unavailability of genomic transmittable pluripotent rat cells, which can sustain their pluripotency following a series of genetic modifications in vitro. This limitation is also due in part to the lack of efficient targeting technologies that allow introduction or deletion of large genomic sequences, or replacement of large genomic DNA sequences with exogenous nucleic acid sequences in pluripotent rat cells. The present invention seeks to solve this problem by providing compositions and methods for modifying a genomic locus of interest in a eukaryotic cell, a mammalian cell, a human cell or a non-human mammalian cell using a large targeting vector (LTVEC) comprising various endogenous or exogenous nucleic acid sequences as described herein. Further methods combine the use of the LTVEC with a CRISPR/Cas system. Compositions and methods for generating a genetically modified non-human animal comprising one or more targeted genetic modifications in their germline are also provided.
Patent NZ-728592-A (NZ)
Title: Self-optimising respiratory therapy system
Inventor: BUCKLEY MARK DAVID
IPC: A62B18/02
Filed: 2015-07-31
Abstract: A computer-implemented method and system for evaluating use of a respiratory therapy device for treating a respiratory disorder of a patient, comprising: receiving, in one or more processors, input data relating to respiratory therapy delivered to the patient via the respiratory therapy device; computing, in the one or more processors, a success prediction score by applying a compliance model to the received input data, the success prediction score representing a success prediction regarding progress of the respiratory therapy, the success prediction score indicating a probability that the patient will be compliant with a predetermined compliance rule; evaluating, by the one or more processors, the success prediction score to trigger one or more communications concerning use of the respiratory therapy device; and transmitting a control command to adjust a setting of the respiratory therapy device based on the evaluation.
Patent NZ-733539-A (NZ)
Title: Manufactured to shape headgear and masks
Inventor: FORMICA JUSTIN JOHN
IPC: A62B18/02
Filed: 2012-08-21
Abstract: A headgear assembly (200) for use in supporting a respiratory mask in position on a patient’s face for positive pressure treatment of the patient. The headgear assembly comprises a fully fashioned unitary structure constructed from yarn, the fully fashioned unitary structure comprising a first portion (210) which forms a shape configured to conform to a patient’s head when the headgear is not engaged with the patient’s head.
Patent NZ-739468-A (NZ)
Title: Terminal device, base station device, communication method, and integrated circuit
Inventor: AIBA TATSUSHI
IPC: H04W72/04
Filed: 2016-08-03
Abstract: A terminal device/method comprising: a reception unit configured to receive, from a base station device, information for one or more aperiodic channel state information (CSI) reports, and information for one or more periodic CSI reports; and a transmission unit configured to transmit CSI reports, wherein in a case that a quantity of the CSI reports exceeds a first number, the first number of CSI reports with the highest priority from the CSI reports are updated based on the priority, and the priority is based on whether each of the CSI reports is an aperiodic CSI report or a periodic CSI report. Plus a base station device/method comprising: a transmission unit configured to transmit, to a terminal device, information for one or more aperiodic channel state information (CSI) reports, and information for one or more periodic CSI reports; and a reception unit configured to receive, from the terminal device, CSI reports, wherein in a case that a quantity of the CSI reports exceeds a first number, the first number of CSI reports with the highest priority from the CSI reports are updated based on the priority, and the priority is based on whether each of the CSI reports is an aperiodic CSI report or a periodic CSI report.
Patent NZ-747805-A (NZ)
Title: Reducing the need for tailings storage dams in mineral flotation
Inventor: FILMER ANTHONY OWEN
IPC: B09B1/00
Filed: 2016-10-21
Abstract: This invention relates to a process for recovering value metals from ore (50) configured such as to substantively reduce or eliminate the need for a tailings storage facility. This object is achieved through an integrated processing system designed to enhance the ratio of sand residue from coarse flotation (62) to the amount of tailings arising from fine flotation (72), and then blending a proportion of coarse and fine flotation gangue materials into a free draining stack (82).