baber/WOPTO huggingface dataset:
Patent CA-2443968-A1 (CA)
Title: Diagnosis and treatment of cancer: i
Inventor: COOMBES RAOUL CHARLES
IPC: C12Q1/68
Filed: 2002-04-11
Abstract: A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A. Genetic constructs and molecules useful in such methods. The methods and compositions are particularly suited to breast cancer.
Patent CA-2448106-A1 (CA)
Title: Process for synchronization in the downstream of multiple users in a point to multipoint system with ofdm modulation
Inventor: RIVEIRO INSUA JUAN CARLOS
IPC: H04L27/26
Filed: 2002-05-17
Abstract: The invention relates to a system that is suitable for bidirectional communication via the electrical network between a headend and numerous user s. Said invention can be used for both time and frequency synchronisation of multiple users in an OFDM (Orthogonal Frequency Division Multiplexing) multi - carrier communication system. The inventive method is characterised in that it consists in generating synchronisation sequences using two identical synchronisation symbols (16) which are transmitted periodically from the headend equipment by means of the downlink to the users. The sampling frequency can then be determined and corrected and, simultaneously, the mome nt at which the OFDM symbol starts can be determined, such that the samples of the signal received by each user match those used in the transmission.</SDOA B>
Patent CA-2448997-A1 (CA)
Inventor: GUMASTE ANAND V
IPC: B65D81/32
Filed: 2002-05-22
Abstract: Controlled quantities of powdered medication are formed in controlled release packages using electrostating metering. Also provided are combination medication therapy delivery packages comprising two or more active pharmaceuticals segregated from one another in a single delivery package.
Patent CA-2449725-A1 (CA)
Title: Compositions de pate pre-levee pouvant passer du congelateur au four, et procedes correspondants
Inventor: SIERZANT ROSEBUD L
IPC: A21D6/00
Filed: 2002-06-06
Abstract: La présente invention concerne des compositions de pâte levée à la levure pouvant passer du congélateur au four, et des procédés permettant de préparer ces compositions. Les compositions de pâte privilégiées comprennent une quantité d'abaisseurs du point de congélation afin d'abaisser la température de point de congélation sans empêcher la formation de glace. Le procédé de préparation de cette composition de pâte peut comprendre une étape de repos après le malaxage.
Patent CA-2449967-A1 (CA)
Inventor: MATE TIMOTHY P
IPC: G01V3/00
Filed: 2002-06-05
Abstract: L'invention concerne un système et un procédé permettant de localiser et de suivre précisément la position d'une cible, telle qu'une tumeur ou autres cibles analogues à l'intérieur d'un corps. Dans un mode de réalisation, le système comprend une ou plusieurs balises excitables pouvant être positionnées dans ou à proximité de la cible; une source d'excitation externe conçue pour exciter à distance les balises afin de produire un signal identifiable; et une pluralité de capteurs espacés dans une géométrie connue les uns par rapport aux autres. Un ordinateur est couplé aux capteurs, il est configuré pour utiliser les mesures des balises afin d'identifier un isocentre de la cible à l'intérieur de la cible. L'ordinateur compare la position de l'isocentre de la cible avec la position de l'isocentre de la machine. L'ordinateur commande également le déplacement du patient et un dispositif de soutien de patient de sorte que l'isocentre de la cible coïncide avec l'isocentre de la machine avant et pendant la radiothérapie.
Patent CA-2451272-A1 (CA)
Inventor: RICHTER JOERN
IPC: A61N1/20
Filed: 2002-06-10
Abstract: L'invention concerne une électrode aiguille de thérapie, notamment destinée à la galvanothérapie percutanée de tumeurs, pouvant être représentée dans des procédés d'imagerie. Ladite électrode présente un revêtement de platine et/ou de matériau isolant. L'invention concerne également un procédé de fabrication de l'électrode aiguille selon l'invention.
Patent CA-2451846-A1 (CA)
Inventor: OHSUGI YOSHIYUKI
IPC: A61K39/00
Filed: 2002-06-28
Abstract: L'invention concerne un vaccin anticarcinogène, qui contient un antigène tumoral renfermant comme ingrédient actif un produit de gène WT1 suppresseur de tumeur ou son fragment peptidique et des liposomes cationiques.
Patent CA-2454093-A1 (CA)
Inventor: LITTLE HERBERT A
IPC: H04L29/06
Filed: 2002-07-16
Abstract: Cette invention concerne un système et un procédé de soutien opérations impliquant de multiples autorités de certification (AC) sur un dispositif de communication. Une interface AC commune est disposée entre une pluralité d'applications de communication sécurisées et une pluralité de composants spécifiques aux AC, chacun de ces composants interagissant avec une AC particulière. Une autre interface commune peut également être utilisée pour coupler de manière fonctionnelle les applications de communication sécurisées aux composants cryptographiques dans le dispositif.
Patent CA-2455331-A1 (CA)
Inventor: OU DUAN LI
IPC: C09D183/08
Filed: 2002-07-18
Abstract: A high refractive index polysiloxane includes siloxane T units of the formul a (I) where A represents an alkylene group having 1 to 4 carbon atoms: n=O or 1; m is at least 1; and Ar is an aryl group substituted by at least one iodine, bromine or chlorine atom, or is a polynuclear aromatic group. The invention includes chlorosilanes having the formula (Ar)m-(A)nSiCl3, useful in forming high refractive index polysiloxanes.
Patent CA-2457620-A1 (CA)
Inventor: SCHIERJOTT RUDOLF
IPC: H05B37/03
Filed: 2002-08-05
Abstract: An illuminated sign for traffic control, in particular for road traffic, which comprises light sources for generation of the sign and a monitoring device for functional monitoring of the light source, whereby the light sources are embodied as light diodes (LED) and the monitoring device is embodied as a device for the limited current loading of the light diodes (LED). The functional monitoring of said sign can be achieved with reasonable technical requirements in both the deactivated and activated state thereof.
Patent CA-2457839-A1 (CA)
Inventor: YOUNG HARVILL
IPC: G06T15/20
Filed: 2002-08-14
Abstract: La présente invention concerne un système et un procédé de modélisation tridimensionnelle automatique permettant la génération d'un modèle tridimensionnel à partir d'une image ou analogue. Par exemple, il permet la génération automatique d'un modèle tridimensionnel pour le visage d'une personne. Le système et le procédé permettent également la génération automatique de gestes/comportements associés à un modèle tridimensionnel de sorte les gestes/comportements soient applicables à d'autres modèles tridimensionnels quelconques.
Patent CA-2458672-A1 (CA)
Title: Efficient search for migration and purge candidates
Inventor: SAAKE MARK
IPC: G06F17/30
Filed: 2002-09-26
Abstract: A computer system (10, fig. 1) configured to store a plurality of files, and a data file (72, fig. 5), which includes inode (62, fig. 3; fig. 4) and migration or purge information associated with the files (fig. 5). The computer system searches the data file to identify files that are candidates for migration or purge (100, 102, fig. 8). A plurality of pathnames associat ed with the files is stored in the data file or a separate data file, and the computer system obtains the pathnames of candidate files from the data file (or separate data file) (350, fig. 13, 106, fig. 8). When candidate files ar e identified, their inodes are used to look up their pathnames in the pluralit y of pathnames (354, fig. 13, fig. 14). The data file may include information about whether a file has been modified and its time of last access (100, 102 , fig. 8). To determine whether a file is a candidate for migration, its entry in the data file is checked to determine whether it has been modified (102, fig. 8). If it has, it is identified as a migration candidate (106, fig. 8). A file is determined to be a purge candidate if it has not been modified and i ts time of last access is older than a predetermined value (110, fig. 8).</SDOA B>
Patent CA-2460363-A1 (CA)
Title: Bi-injection trigger sprayer nozzle cap
Inventor: SWEETON STEVEN L
IPC: B65D47/34
Filed: 2004-03-04
Abstract: A nozzle cap of a trigger actuated pump sprayer is produced of two differe nt materials using a bi-injection molding process for delimiting the markings o n the outer faces of the four walls of the cap serving as indicia relating to specific rotative positions of the cap.
Patent CA-2460745-A1 (CA)
Title: Packaging systems, apparatus and method therefor
Inventor: BONNAIN JEAN-CHRISTOPHE
IPC: B65B57/00
Filed: 2002-09-20
Abstract: A system for monitoring the condition of a packaging machine during operation and diagnosing potential problems in the performance of the machine. The system comprises an input device, an output device and a processing unit that supports a user interface presented by the output device. The processing unit is arranged to permit a user, when in use, to input via the user interface a number of pre-determined parameters to measure one or more elements or assemblies in the machine, to receive information from one or more sensors measuring the element or assembly and to analyse the information with the parameter to render via the output device a signal.
Patent CA-2461059-A1 (CA)
Title: Concrete-moulded stone and ready-to-assemble construction made of moulded stones
Inventor: HAGENAH GERHARD
IPC: E01C5/06
Filed: 2002-08-24
Abstract: An essentially quadrate paving stone having a corresponding base block (21) is provided on all four side surfaces (25, 26) with flange-like, upright spacers (22) which are spaced apart from each other at intervals corresponding approximately to the width of the spacers, making it possible for them to make an interlocking connection with adjacent shaped paving stones of the same type. Furthermore, the bottom side (24) of the paving stone features a number of transverse, gutter-like depressions resulting in the formation of ribs between these depressions. This creates an additional dentification, or anchoring, in the bed surface of the installed paving stones.
Patent CA-2461159-A1 (CA)
Inventor: STOBIE ALAN
IPC: A61P1/04
Filed: 2002-10-03
Abstract: L'invention concerne un composé de formule (I) ou les sels correspondants acceptables pharmaceutiquement, où R?1¿ représente l'hydrogène, un halogène ou un alkyle, R?2¿ et R?3¿ représentent indépendamment l'hydrogène, un alkyle, un alkényle, un alkynyle, un aminoalkyle ou un hydroxyalkyle ou R?2¿ et R?3¿ pris avec l'atome d'azote auquel ils sont liés peuvent former un hétérocycle, R?4¿ représente l'hydrogène, un halogène, un acyle, un amino, un amido, un aryle, un arylalkyle ou un hétéroaryle, R?5¿ représente l'hydrogène, un halogène, un alkyle, un alkényle, un alkynyle, un acyle, un amino, un amido, un aryle, un arylalkyle ou un hétéroaryle, R?6¿ représente l'hydrogène, un alkyle ou un alkoxyalkyle, X représente NR?9¿, R?9¿ représentant l'hydrogène ou un alkyle, et Y représente (CR?7¿R?8¿), n étant un nombre entier compris entre 0 et 5. Ces composés présentent une activité de liaison au récepteur 5-HT¿4? et sont donc utilisés pour traiter le reflux gastrooesophagien pathologique, la dyspepsie non ulcéreuse, la dyspepsie fonctionnelle, le côlon irritable ou un trouble similaire chez un mammalien, notamment des êtres humains. Ladite invention a également trait à une composition pharmaceutique renfermant le composé susmentionné.
Patent CA-2461357-A1 (CA)
Inventor: WRIGHT MATTHEW CHRISTOPHER
IPC: G01N33/74
Filed: 2002-09-25
Abstract: Provided are methods of inhibiting proliferation and/or trans-differentiation of hepatic stellate cells, which method comprises the step of contacting hepatic stellate cells with a ligand of the low affinity glucocorticoid binding site (LAGS), which may be the rat p28 receptor or the human hpr6.6 receptor. The invention also provides ligands for use in such methods (e.g.  pregnenolone 16-alpha carbonitrile) and methods for screening for the same (e.g. based on competition or displacement assays using LAGS ligands such as dexamethasone). Such ligands may be used in the treatment of liver disorders.
Patent CA-2462425-A1 (CA)
Title: Therapeutically useful triethyleneglycol cholesteryl oligonucleotides
Inventor: PHILLIPS NIGEL C
IPC: A61K47/48
Filed: 2002-10-03
Abstract: The present invention provides a composition comprising a 5'-OR, 3'- TEG  cholesteryl synthetic sequence wherein the sequence is SEQ ID NO:5, SEQ ID  NO:6, SEQ ID NO:7, SEQ ID NO:8, and a pharmaceutically acceptable carrier. The present invention also provides methods of using of this composition in preparation of medicaments, and methods of using this composition for induction of a response in a cell, including but not limited to inhibition of cellular proliferation, induction of cell cycle arrest, induction of caspase activation, cleavage of poly(ADP-ribose) polymerase, induction of apoptosis or modulation of extracellular matrix-cell interactions, or combinations thereof, in cancer cells and/or synovial cells.
Patent CA-2465235-A1 (CA)
Title: System and method for selecting electronic documents from a physical document and for displaying said electronic documents over said physical document
Inventor: INCERTIS CARRO FERNANDO
IPC: G06F3/0489
Filed: 2002-09-12
Abstract: The present invention discloses a system and a method for selecting, accessi ng and retrieving directly from a physical (i.e., hard-copy) document, hypertex t documents located on a user workstation or on one or a plurality of servers connected to a communication network, and for displaying the retrieved hypertext documents over said physical document. The information is accessed by the user simply by touching with a finger items (i.e., words, letters, symbols, pictures, icons, ...) that are highlighted on an electronic hyperte xt document displayed over the physical document. The method, for use in a user system comprises the steps of: - identifying a physical document, this physical document comprising one or a plurality of pages; - identifying a pa ge of said physical document; - identifying and locating an electronic document associated with the identified page referring to a document hyperlink table; said document hyperlink table comprising for each page of the physical document the identification and location of an electronic document; - accessing and retrieving the electronic document associated with the identified page; - displaying the retrieved electronic document by means of an opto-touch foil placed over the identified page.
Patent CA-2465338-A1 (CA)
Title: Damped accessory drive system including a motor/generator
Inventor: SERKH ALEXANDER
IPC: F16H1/00
Filed: 2002-11-01
Abstract: The invention is an improved internal combustion engine having a crankshaft, an accessory, a motor/generator, and a belt-drive system. The belt drive systems includes a crankshaft pulley, an accessory pulley, a motor/generator pulley, a belt tensioner, a belt tensioner pulley, and a power transmission belt trained about the crankshaft pulley, the accessory pulley, the motor/generator pulley, and the belt tensioner pulley. The tensioner pulley contacts the belt at a start-slack-side span. It is improved by the tensioner being asymmetrically biased in a direction tending to cause the power transmission belt to be under tension.
Patent CA-2466286-A1 (CA)
Title: Composition and method
Inventor: WEDEKIND KAREN J
IPC: A23K1/18
Filed: 2002-11-06
Abstract: A composition which comprises about 0.1 to about 4.5 mg selenium/kg of diet on a dry matter basis.
Patent CA-2468279-A1 (CA)
Title: A system and a method for operating on-line state lottery games
Inventor: YACENDA MICHAEL W
IPC: G06F17/00
Filed: 2001-11-02
Abstract: The present invention relates to a system and a method for facilitating governmental lottery games with a screening, a verification, and a subscription play function. A lottery agent system of the present invention includes a plurality of player terminals (10) on which lottery players can play lottery games, including purchasing and receiving lottery tickets, an agent server (30) for facilitating the purchase and screening of players and winning tickets, and a governmental lottery administrator (40) for providing security or serial numbers for verification. The present invention further discloses a method for claiming awards for the winning tickets upon a drawing of winning numbers. Upon receiving information of the winning tickets, the state provides the agent server (30) with claim validation numbers associated with the winning tickets for claims on lottery awards by winning players.
Patent CA-2468335-A1 (CA)
Title: Precurseurs de chondrocytes derives de cellules souches embryonnaires humaines
Inventor: THIES R SCOTT
IPC: A61K35/12
Filed: 2002-12-06
Abstract: L'invention concerne un système permettant d'obtenir des cellules à partir d'une lignée de chondrocytes par le biais d'une différentiation de cellules souches pluripotentes de primate. Ce procédé consiste à cultiver les cellules en tant que micromasse ou sous une autre forme d'agrégat, dans un cocktail d'agents de différentiation permettant de faciliter la croissance du type de cellule voulu. La descendance permet de synthétiser de l'aggrécan ou du collagène de type II, ou d'autres produits caractéristiques de la lignée de chondrocytes. Les chondrocytes et les cellules précurseurs de chondrocytes obtenus selon l'invention sont adaptés à une utilisation à la fois dans le domaine de la recherche et dans le domaine de la thérapie clinique.
Patent CA-2470394-A1 (CA)
Inventor: WONG SAMUEL
IPC: G06Q10/06
Filed: 2002-12-09
Abstract: A method and system for assisting and expediting an organization toward high er levels of the Capability Maturity Model (CMM). The invention provides a meth od for producing a more mature product. The method comprises the managing of an organization developing the product, whereby management comprises managing organizational personnel and implementing a product improvement process. The method may comprise managing a product development project and the delivery of the product. Actions undertaken during the organizational management affects implementation of the project and delivery managements, and the actions undertaker during the project and delivery management affect implementation of the organizational management. The method may be implemented using electroni c hardware and software, locally or over a network such as an intranet or the Internet (12). The method may be implemented using a document management system to administer files and assist a user in the creation of documents related to the steps in the method. The invention uses WebDAV-based communication to coordinate access to multiple document repositories.</SDOAB >
Patent CA-2472821-A1 (CA)
Inventor: NAKAMOTO KOJI
IPC: C07D233/54
Filed: 2003-01-09
Abstract: L'invention concerne un procédé industriel avantageux pour l'élaboration d'inhibiteur de C¿17, 20? - lyase stéroïde représenté par la formule générale (I); et un réactif de Reformatsky sous forme stable, approprié à l'utilisation dans le processus de production correspondant. L'opération consiste à réduire un dérivé de composé de .beta.-hydroxy ester spécifique issu d'un composé carbonyle spécifique, par la réaction de Reformatsky, ou un sel correspondant du composé, en présence de composé de complexe métal/hydrogène et d'un halogénure de métal, que l'on soumet ensuite à une cyclisation, donnant un composé représenté par la formule générale (I). Pour les besoins de ladite formule, les symboles sont tels que définis dans la description. S'agissant de la réaction de Reformatsky, une solution stable du composé représenté par BrZnCH¿2?COOC¿2?H¿5?, ou des cristaux du composé représenté par (BrZnCH¿2?COOC¿2?H¿5?.THF)¿2?, sont utiles.
Patent CA-2473350-A1 (CA)
Title: Lightweight structure especially for an aircraft and method for making such a structure
Inventor: VICHNIAKOV ALEXEI
IPC: B32B15/08
Filed: 2004-07-08
Abstract: An additional fiber reinforced layer reduces crack propagation in a lightweight structure of an outer skin adhesively banded to a reinforcing frame for this purpose the additional fiber reinforced layer is interposed between the outer skin and the frame and adhesively bonded to the outer skin and to the frame.      The additional layer has reinforcing fibers extending in parallel to each other or the reinforcing fibers are woven into a fabric embedded in a synthetic adhesive bonding material. The embedding of the parallel fibers or of the fiber fabric in the bonding material is performed either prior to the bonding or during the bonding of the additional layer to the outer skin and to the reinforcing frame.
Patent CA-2473788-A1 (CA)
Inventor: BUZYN AGNES
IPC: G01N33/574
Filed: 2002-12-23
Abstract: The application relates to the use of at least one protein selected from the group consisting of FADD proteins and phosphorylated p38-MAPK, as a marker for absence of in vivo tumour. This use may further be complemented by the use of the FasL protein as a marker for presence of in vivo tumour. The (respective) amount(s) of FADD proteins and phosphorylated p38-MAPK indeed decrease, sometimes up to zero, with tumour development, while FasL expression is gained. FADD proteins are secreted from out of the tumour cells into their extracellular environment. A low cellular amount and a high extracellular amount of FADD proteins are prognostic of resistance to chemotherapy.
Patent CA-2473943-A1 (CA)
Title: Multiplexage par modulation
Inventor: WEI YONGBIN
IPC: H04J13/04
Filed: 2003-10-09
Abstract: L'invention concerne des systèmes et des techniques ayant trait aux télécommunications. Ces systèmes et techniques comprennent des transmissions établies sur un canal physique comportant une pluralité de canaux de modulation qui présentent chacun une capacité de canal, et consistent à attribuer une pluralité de trains de données aux canaux de modulation en fonction de leur capacité, et à moduler les trains de données en vue de la transmission de ceux-ci sur le canal physique selon l'attribution des trains de données aux canaux de modulation.
Patent CA-2481691-A1 (CA)
Inventor: WOOD WILLIAM I
IPC: C07K14/705
Filed: 2000-08-24
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.