baber/WOPTO huggingface dataset:
Patent DE-60307262-D1 (DE)
Inventor: BELEW MAKONNEN
IPC: C07K14/765
Filed: 2003-05-09
Granted: 2006-09-14
Abstract: The present invention is a method of purifying recombinant human serum albumin (rHSA) from a solution, which method comprises to subject a cell culture supernatant (CCS) comprising rHSA cation exchange on a bimodal high salt tolerant matrix; hydrophobic interaction chromatography (HIC); anion exchange; and recovering the purified rHSA. The bimodal high salt tolerant cation exchange matrix used enables performing a purification of a cell culture supernatant directly, in the sense that no further dilution thereof is necessary. Due to its high binding capacity, said bimodal cation exchange matrix also allows use of a smaller amount of matrix as compared to a corresponding conventional cation exchanger matrix. Accordingly, the present invention allows substantial savings as regards volumes and consequently operation costs.
Patent DE-60309334-D1 (DE)
Inventor: DOJAN J
IPC: A43B13/20
Filed: 2003-09-10
Granted: 2006-12-07
Abstract: Valves and methods for manufacturing the valves are disclosed. The valves are formed from a plurality of flexible polymer layers. A radio frequency bonding process, or the like, is utilized to form welds between the various layers. In general, a sub-assembly is formed that includes a valve layer bonded to a substrate layer. The sub-assembly is bonded to a second element such that a channel is formed between the valve layer and the second element. The channel includes an inlet, an outlet, and a pair of weld beads located in the inlet that place the inlet in an open configuration.
Patent DE-60309644-D1 (DE)
Inventor: IKAMI JUN
IPC: G03G15/08
Filed: 2003-09-24
Granted: 2006-12-28
Abstract: An electrostatic developing toner for use in an image-forming apparatus in which an electrostatic latent image is formed on a photoconductive film on the circumferential surface of a photoconductive drum, and toner is supplied to the electrostatic latent image from a non-magnetic developing roller, which is in contact with the photoconductive drum, to develop the electrostatic latent image, characterised in that:  the toner comprises iron oxide particles in resin particles; and the ratio (d/D) between the average particle diameter D of the toner and the average particle diameter d of the iron oxide particles is from 0.01 to 0.03.  <IMAGE>
Patent DE-60311436-D1 (DE)
Inventor: RYDBERG TOMMY
IPC: B31B45/00
Filed: 2003-02-12
Granted: 2007-03-15
Abstract: A machine for punching out and optionally slitting corrugated cardboard blanks from a web ( 2 ) of corrugated cardboard while simultaneously applying folding lines onto said corrugated cardboard blanks ( 2 a). The machine includes two interacting punching tools, such as two interacting cylinders ( 4, 5 ), the punching, slitting and folding line tools being mounted on said cylinders. A delivery unit ( 7, 7 a) is mounted immediately after the two interacting cylinders ( 4, 5 ) said delivery unit ( 7, 7 a) being adapted to be connected to an erection module ( 1 b) by means of a coupling member ( 10, 15 ). The erection module ( 1 b) is adapted to erect the plane corrugated cardboard blanks ( 2 a) punched out and provided with folding lines into a permanent or semipermanent three-dimensional shape. In this manner a significant logistics problem is solved, said problem concerning the moving of corrugated cardboard blanks punched out, but not yet erected. In addition, the machine is very reliable.
Patent DE-60314365-D1 (DE)
Inventor: WEDEL MARTIN
IPC: H04M1/725
Filed: 2003-02-10
Granted: 2007-07-26
Abstract: A combined speaker and antenna arrangement for a communication terminal, comprising a support structure (100) carrying a first antenna element (101), and a second antenna element (31) arranged at a predetermined distance from said first antenna element. Said second antenna element is a conductive first portion (31) of a sheet of flexible film, and an elongated second portion (32) of said flexible film, carrying a conductive lead, extends from adjacent to said first portion to a speaker (4 1 ) connected to an outer end of said elongated second portion. The second, elongated, portion is bent such that said speaker is positioned between said film and said support structure, adjacent to an aperture in said first portion. <IMAGE> <IMAGE>
Patent DE-60315499-D1 (DE)
Inventor: PARENT MICHAEL J
IPC: C09K13/04
Filed: 2003-09-17
Granted: 2007-09-20
Abstract: Novel aqueous, acid etch solutions comprising a fluorinated surfactant are provided. The etch solutions are used with a wide variety of substrates, for example, in the etching of silicon oxide-containing substrates.
Patent DE-60316414-D1 (DE)
Inventor: MARTI SENDRA JAVIER
IPC: G02B6/00
Filed: 2003-03-14
Granted: 2007-10-31
Abstract: Multiple delay line based on AWG with a feedback configuration by means of sections of a dispersive optical medium, in which, due to the effect of the dispersion of the sections of the dispersive optical medium, the use of simultaneous multiple wavelengths (WDM) allows a large number of delays to be achieved, that can be optically varied by means of the individual or joint tuning of the multiple wavelengths. The application of the present invention is in any field in which it is necessary to obtain a large number of delays for example, such as occurs in the field of optical shaping of beams for antenna grouping. Other fields of application are analogue-digital optical converters, optical time division multiplexing (OTDM) or the optical systems based on code multiplexing (CDMA). <IMAGE>
Patent DE-60321959-D1 (DE)
Inventor: DRENT EIT
IPC: B01J31/24
Filed: 2003-12-16
Granted: 2008-08-14
Abstract: The invention pertains to a hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol comprising a first step of reacting at an elevated temperature in a reactor the ethylenically unsaturated compound, carbon monoxide, hydrogen, and a phosphine-containing cobalt hydroformylation catalyst, which are dissolved in a solvent, followed by a second step of separating a mixture comprising the alcohol and heavy ends from a solution comprising the catalyst and the solvent, followed by a third step of recycling the solution to the reactor.
Patent DE-60324628-D1 (DE)
Inventor: ITO ATSUSHI
IPC: B41J2/14
Filed: 2003-05-09
Granted: 2008-12-24
Abstract: An ink-jet head of the present invention comprising a plurality of ink ejecting nozzles; a first flat plate (15,P1) forming therein a plurality of pressure chambers (36) communicating with their respective nozzles (35); a second flat plate (13X,13Y,P2) forming therein a common ink chamber (7) to distribute and feed the ink to the pressure chambers; and a third flat plate (P3,14Y) interposed between the first flat plate and the second flat plate and forming therein a restricted passage (43) to restrict an ink flow, one end of which is connected to the pressure chamber and the other end of which is connected to the common ink chamber. The restricted passage is formed in the third flat plate, to be elongated along a direction of a surface of the third flat plate and is extended in a direction parallel with a plane formed by the pressure chambers. <IMAGE>
Patent DE-60325942-D1 (DE)
Inventor: SON HO-SUN
IPC: C12N15/86
Filed: 2003-03-08
Granted: 2009-03-12
Abstract: Disclosed are the methods for producing recombinant viruses using in vitro site-specific recombination. In the present invention, linear viral genomic DNAs are digested to two segments, and are subjected to in vitro site-specific recombination with desired genomic materials flanked with site-specific recombinase sites. According to the present invention, since the site-specific recombination mixture can be applied to host cells without further procedures of selecting the recombinant viral genomic DNAs, it is possible to obtain numerous recombinant viruses rapidly at the same time. Thus, the present invention can be used as a high throughput system to generate hundreds or thousands of recombinant viruses.
Patent DE-60330669-D1 (DE)
Inventor: AVDEEF ALEX
IPC: G01N13/04
Filed: 2003-01-23
Granted: 2010-02-04
Abstract: This invention improves the PAMPA (parallel artificial membrane permeability assay) method used in pharmaceutical, biotechnological, and agrochemical R&D. This new high-throughput method and apparatus for measurement of permeability and membrane retention of compounds overcomes shortcomings of prior art and includes sensitivity and speed enhancing reagents. The phospholipid membranes used here consist of 10-74% wt/vol soybean lecithin extract dissolved in dodecane. Concentrations are measured by direct UV spectroscopy. To reduce membrane retention, surfactants, cyclodextrins, or water-soluble lipophilic polymers with low UV absorption are used in the acceptor comparment of the permeation cells and create an artificial sink state. A pH gradient established between donor and acceptor solutions creates a secondary sink state. This "double-sink" makes successful modeling of passive-diffusion transport of molecules possible. By accelerating transport of certain molecules, it shortens measurement time and increases assay throughput. A new permeability equation accounts for the "double-sink" condition as well as membrane retention.
Patent DE-60331168-D1 (DE)
Inventor: WIESENDANGER ROLF
IPC: C07C69/54
Filed: 2003-12-18
Granted: 2010-03-18
Abstract: Epoxy acrylates of the formulae (A), (B) and epoxy acrylate mixtures comprising at least one of the compounds (A) or (B) are novel and find use in coating materials or adhesives featuring high UV stability
Patent DE-60331319-D1 (DE)
Inventor: HAGEMAN ROBERT JOHAN
IPC: A23L33/15
Filed: 2003-06-19
Granted: 2010-04-01
Abstract: There is provided a nutritional or pharmaceutical composition comprising a protein fraction containing L-serine and an energy metabolism precursor wherein the composition is free of glycine or if glycine is present within the composition, the weight ratio of L-serine: glycine after hydrolysis of the composition is of more than 2.7:1, which composition provides an effective creatine response within mammals muscle and methylation reaction capacity of organisms.
Patent DE-60336065-D1 (DE)
Inventor: ROTTER TERRENCE M
IPC: F01L1/14
Filed: 2003-07-15
Granted: 2011-03-31
Abstract: A valve train in an internal combustion engine, and a method of adjusting the valve timing setting of a valve in such a valve train, are disclosed. In one embodiment, the present invention relates to an engine that includes a crankcase with a cylinder, a valve, a push rod, and a rocker arm supported by the crankcase and coupling the valve to the push rod. The internal combustion engine further includes a cam rotatably supported by the crankcase, and a cam follower arm having first and second ends and, proximate the second end, having bottom and top surfaces. The cam follower arm is rotatably supported by the crankcase about a pivot point proximate the first end. The bottom surface proximate the second end slidingly interfaces the cam, and the top surface proximate the second end interfaces the push rod.
Patent DE-68904121-D1 (DE)
Inventor: HUNTER CHRISTOPHER
IPC: A61K31/19
Filed: 1989-06-01
Granted: 1993-02-11
Abstract: Complexes of  beta -cyclodextrin with various salts of ibuprofen are described in which the molar ratios of ibuprofen to  beta -cyclodextrin are within the range of from 1:0.20 to 1:0.75. The preferred salt of ibuprofen is the sodium salt. The complexes have enhanced taste profile and bioavailability. Also disclosed are methods for preparing the complexes and also pharmaceutical compositions thereof.
Patent DE-68905704-D1 (DE)
Inventor: ALVISI CESARE
IPC: F24H4/02
Filed: 1989-06-28
Granted: 1993-05-06
Abstract: An integrated apparatus for producing warm or sanitary water, comprising in combination a heat pump having a compressor (15), a condenser (19), an expansion valve and an evaporator (54) connected in series to convey a refrigerating fluid, an electric or fuel-powered (gas- or gas oil-powered) boiler (16, 17, 30) accommodating the condenser (19) of the heat pump, and at least one greenhouse effect heat source (49-52). A chamber (46) for receiving the evaporator (54) of the heat pump is provided downstream of the boiler and is in communication both with the boiler (16, 17, 30) to receive therefrom the flue gases and with the greenhouse effect heat source to receive therefrom warm air which, together with the exhaust fumes, gives off heat to the evaporator (54).
Patent DE-68909260-D1 (DE)
Inventor: GUILLET REMI
IPC: G01N31/12
Filed: 1989-01-27
Granted: 1993-10-28
Abstract: To determine the calorific value of the combustible energy-carrying matter, particularly in gaseous form, flowing in a pipe (1), the combustible matter is burnt in a combustion chamber (110) suitable for measuring a small known fraction (qgas) of the mass flow rate (Qgas) of the matter. The air-fuel ratio (f) applying to the combustion in the chamber (110) is measured by means of a measuring circuit (104'). The mass flow rate of the air (qair) used for the combustion in a pipe (103) is measured by means of a measuring device (106). A computer (160) is used to deduce the calorific value (Pu) of the matter flowing in the pipe (1) from the measurements of the mass flow rate of the air (qair) used for the combustion flowing in the pipe (103) and from the measurement of the air-fuel ratio (f). In a variant, the air-fuel ratio (f) may be adjusted using a control circuit (104). <IMAGE>
Patent DE-68910289-D1 (DE)
Inventor: ANTHONSEN NIELS A
IPC: D21G1/02
Filed: 1989-12-07
Granted: 1993-12-02
Abstract: A novel rotary joint (2) or coupling which couples a rotating element (6) to a non-rotating element (7) and allows for the passage of a process fluid (24) from the rotating element (6) to the non-rotating element (7) or vice versa, and seals the flowing process fluid (24) from the external environment. A rotary joint (2) useful for connecting a stationary object (7) to a rotating object (6) comprising: (a) bearing housing means (4) adapted to be joined to either the rotating (6) or the stationary object (7); (b) fluid conveying means (5) (14) adapted to be joined to either the stationary (7) or rotating object (6) to which the bearing housing means (4) is not joined; (c) sealing means (16) (18) positioned between the fluid conveying means (5) (14) and the bearing housing means (4) for preventing migration of fluid (24) from the fluid conveying means (5) (14) into the bearing housing means (4); and (d) rotatable bearing means (9) (10) positioned between the bearing housing means (4) and the fluid conveying means (5) (14), and exterior to the sealing means (16) (18), said bearing means (9) (10) being lubricated and cooled by a lubricating means (32) (34).
Patent DE-68920393-D1 (DE)
Inventor: KENYON RONALD WYNFORD
IPC: C07D495/04
Filed: 1989-09-15
Granted: 1995-02-16
Abstract: A process for the preparation of a polycyclic dye of Formula I: <CHEM>  by reacting a phenyltartronic acid of Formula II: <CHEM>  wherein  W is - NR<1>R<2> or - OR<3>; R<3> is H or an optionally substituted alkyl, alkenyl, cycloalkyl or aralkyl group; R<1> & R<2> are each independently H or an optionally substituted alkyl, alkenyl, cycloalkyl, aralkyl or aryl group; or R<1> & R<2> together with the nitrogen atom to which they are attached form a heterocyclic ring; or R<1> or R<2> together with the nitrogen atom and the adjacent carbon atom of Ring B form a heterocyclic ring; and Ring B is unsubstituted, apart from the group W, or is substituted by one or two further groups;  with either (a) a compound of Formula III: <CHEM>  wherein, Z<1> & Z<2> are each independently - O -, - S - or - NY - in which Y is H, an optionally-substituted hydrocarbon group or an acyl group; X<1> & X<2> are each independently selected from H, halogen, cyano, alkyl, aryl, carbamoyl, sulphamoyl, COOH and carboxylic acid ester; & Ring A is unsubstituted or is substituted by from one to three groups;  or (b) a compound of Formula IV: <CHEM>  wherein Z<1>, Z<2>, X<1> and X<2> are as hereinbefore defined; and oxidation of the intermediate compound to dehydrogenate the peripheral heterocyclic rings. The invention also comprises a product of the aforementioned process which is suitable for the colouration of polyester textile material in shades from green through to reddish-blue of the formula: <CHEM>  wherein: X<1> & X<2> each independently is H, cyano, alkyl, aryl, carbamoyl, sulphamoyl, COOH or carboxylic acid ester; Z<1> & Z<2> each independently is - O -, - S - or - NY - in which Y is H, an optionally-substituted hydrocarbon group or an acyl group; R<1> & R<2> each independently is H or an optionally substituted alkyl, alkenyl, cycloalkyl, aryl or aralkyl group; or R<1> & R<2> together with the N atom to which they are attached, form a heterocycle; R<4> & R<5> each independently is H, halogen or an optionally substituted alkyl, alkenyl or alkoxy group; or R<1> & R<4> together with the N atom and the two carbon atoms in Ring B to which they are attached form a heterocycle fused to Ring B; or R<2> & R<5> together with the N atom and the two carbon atoms in Ring B to which they are attached form a heterocycle fused to Ring B; R<6> is H, halogen, an optionally substituted alkyl or alkoxy group or a group NR<1>R<2> in which each of R<1> and R<2> independently is as hereinbefore defined; R<7> & R<8> each independently is H, halogen or an optionally substituted alkyl, alkenyl or alkoxy group; or R<1> & R<7> together with the N atom and the two carbon atoms in Ring A to which they are attached form a heterocycle fused to Ring A; or R<2> & R<8> together with the N atom and the two carbon atoms in Ring A to which they are attached form a heterocycle fused to Ring A; and where R<6> is NR<1>R<2>, this may be the same as or different from the NR<1>R<2> group present in Ring B.
Patent DE-68926970-D1 (DE)
Inventor: REDLICH ROBERT W
IPC: G01D3/028
Filed: 1989-01-22
Granted: 1996-09-19
Abstract: The relative displacement of two bodies is measured by moving an electrically conducting, non-ferromagnetic wall means in proportion to the relative movement of the bodies in order to increase its overlapping, telescoping relationship to a first current conducting coil while simultaneously decreasing its overlapping, telescoping relationship to a second current conducting coil. Each of the coils are excited with an AC signal at a frequency which is at least high enough that the skin depth of the wall means is less than the physical depth of the wall means. A signal is detected which is proportional to the difference in the amplitude of the voltages across the two coils which results in improved sensitivity while improving linearity and substantially reducing temperature dependence.
Patent DE-69002800-D1 (DE)
Inventor: CHAWLA BRINDRA PAUL SINGH
IPC: A61M13/00
Filed: 1990-06-15
Granted: 1993-09-23
Abstract: A disposable device for the administration of powdered inhalation medicament is provided which comprises a rigid medicament reservoir (4) holding a unit dose of medicament (10) and having air inlet means (5,7) and medicament outlet means (8); and closure means (3) which are removable in use; wherein the medicament (10) held in the reservoir (4) is in loose powder form.
Patent DE-69003711-D1 (DE)
Inventor: GLANCY CHARLES WILLIAM
IPC: C09D7/00
Filed: 1990-03-21
Granted: 1993-11-11
Abstract: The precursor coating compositions contain water and at least one organic solvent and are particularly suitable for being admixed with at least one supercritical fluid used as a viscosity reduction diluent and this resultant liquid mixture of supercritical fluid and precursor coating composition is sprayed onto a substrate to be coated. Processes for spraying this precursor mixture are also disclosed.
Patent DE-69012347-D1 (DE)
Inventor: SUBLETT BOBBY
IPC: B29C49/04
Filed: 1990-11-28
Granted: 1994-10-13
Abstract: Disclosed are copolyesters containing residues of terephthalic acid, ethylene, glycol, 1,4-cyclohexanedimethanol and a trifunctional monomer which are useful in manufacturing rigid containers by extrusion blow-molding processes.
Patent DE-69019609-D1 (DE)
Inventor: FUJISAWA YUKIO
IPC: C07K16/08
Filed: 1990-07-05
Granted: 1995-06-29
Abstract: Disclosed are (1) a fused protein obtained by combining an antigen used for vaccine and a lymphokine by the application of gene engineering, (2) a recombinant DNA containing a nucleotide sequence coding for the above fused protein, (3) a transformant bearing the above recombinant DNA, (4) a method for producing the fused protein which comprises cultivating the above transformant, producing and accumulating the above fused protein in a culture, and collecting the fused protein, and (5) a hybrid protein obtained by chemically combining an antigen used for vaccine with a lymphokine. The resulting fused and hybrid proteins have strong immunogenicity.
Patent DE-69102369-D1 (DE)
Inventor: MARNAY THIERRY
IPC: A61B17/02
Filed: 1991-03-04
Granted: 1994-07-14
Abstract: PCT No. PCT/FR91/00173 Sec. 371 Date Aug. 4, 1992 Sec. 102(e) Date Aug. 4, 1992 PCT Filed Mar. 4, 1991 PCT Pub. No. WO91/13598 PCT Pub. Date Sep. 19, 1991.The invention concerns a prosthesis for intervertebral discs designed to be substituted for fibrocartilaginous discs ensuring connection between the vertebrae of the spinal column and its instruments for implantation. The prosthesis is composed mainly of two plates (110, 120) each equipped with anchoring flaps (1110, 1210) separated by a joint (20) composed of a spherical cap (21) with a cylindrical base (22), of the same diameter, made in the upper side of the lower plate (120). Each of the plates (110, 120) includes, on the back, threaded holes (115, 116, 125, 126) located parallel to the anchoring flaps (1110, 1210).
Patent DE-69102907-D1 (DE)
Inventor: SUNDSTROEM GUSTAF FOLKE
IPC: B01D21/00
Filed: 1991-02-12
Granted: 1994-08-25
Abstract: A settling apparatus for the separation of amalgam from waste water in a dental procedure includes an inclined passage through which the water is caused to flow from below and upwards while depositing amalgam. The inclined passage (9A) has an inclination of between 3 DEG and 15 DEG . It is filled with a large number of thin-walled, narrow tubes (17), which contact each other in a side-by-side manner. The water flows from below and upwards through the tubes and through the channels between the tubes while amalgam is settled and deposited on the interior, as well as on the exterior, surfaces of the tubes. <IMAGE>
Patent DE-69108691-D1 (DE)
Inventor: SERPELLONI MICHEL
IPC: A23L27/30
Filed: 1991-12-12
Granted: 1995-05-11
Abstract: The invention relates to a directly compressible pulverulent composition based on xylitol, which composition possesses a compressibility, determined in a test A, of more than 70 N. The invention also relates to the process for manufacturing this directly compressible pulverulent composition and to the use of the composition for the manufacture of tablets or confectionary items, in particular of the chewing gum type.