baber/WOPTO huggingface dataset:
Patent EP-1002113-A2 (EP)
Inventor: FALCO SAVERIO CARL
IPC: C12N9/02
Filed: 1998-06-11
Abstract: This invention relates to an isolated nucleic acid fragment encoding a plant enzyme that catalyze steps in the biosynthesis of lysine, threonine, methionine, cysteine and isoleucine from aspartate, the enzyme being a member selected from the group consisting of aspartic semialedhyde dehydrogenase, diaminopimelate decarboxylase, homoserine kinase, cysteine synthase and cystathionine β-lyase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the enzyme in a transformed host cell.
Patent EP-1027325-A2 (EP)
Inventor: KOZAK ALEXANDER
IPC: A61K31/223
Filed: 1998-09-27
Abstract: The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters comprising a covalent conjugate of a BAPTA and a pharmaceutically acceptable alcohol. The diesters are useful in a method for treating a condition or disease related to an excess of divalent metal ions, and in particular for the treatment of a condition or disease related to elevated levels of intracellular calcium ions, such as in brain or cardiac ischemia, stroke, epilepsy, Alzheimer's disease or cardiac arrhythmia and in open heart surgery.
Patent EP-1012320-A2 (EP)
Inventor: SCHNECK JONATHAN
IPC: C07K14/725
Filed: 1998-09-11
Abstract: On a élaboré des complexes peptide/CMH divalents pour améliorer l'affinité effective des analogues solubles de molécules du type peptide/CMH vis-à-vis de leurs ligands correspondants. En utilisant une technique à base d'ADN recombiné, on a ligaturé de l'ADN codant le CMH de classe I sur de l'ADN codant la chaîne polypeptidique lourde Ig murine. Les complexes CMH/Ig ont permis de procéder à un chargement homogène avec les peptides visés. Les résultats de la cytométrie de flux ont montré que les complexes pepCMH/Ig avaient une haute affinité de liaison spécifique avec des cellules comportant leurs récepteurs correspondants. Par ailleurs, les complexes pepCMH/Ig interviennent utilement dans la modulation des fonctions effectrices des cellules T spécifiques de l'antigène. En outre, lesdits complexes interviennent utilement dans l'étude des interactions du type récepteur des cellules T (TcR)/CMH et dans le repérage des lymphocytes, et ils répondent à différentes utilisations en tant que régulateurs spécifiques des réponses immunes.
Patent EP-1025605-A2 (EP)
Inventor: CISAR ALAN J
IPC: C25B9/17
Filed: 1998-09-10
Abstract: A fuel cell design for use at low pressure. The invention has a reduced number of component parts to reduce fabrication costs, as well as a simpler design that permits the size of the system to be reduced at the same time as performance is being improved. In the present design, an adjacent anode and cathode pair are fabricated using a common conductive element, with that conductive element serving to conduct the current from one cell to the adjacent one. This produces a small and simple system suitable for operating with gas fuels or alternatively directly with liquid fuels, such as methanol, dimethoxymethane, or trimethoxymethane. The use of these liquid fuels permits the storage of more energy in less volume while at the same time eliminating the need for handling compressed gases which further simplifies the fuel cell system. The electrical power output of the design of this invention can be further increased by adding a passage for cooling the stack through contact with a coolant. In particular the invention relates to a low pressure gas electrode, comprising an electrically conducting substrate wherein the substrate comprises at least two opposite faces; a plurality of openings allowing passage from one face to an opposite face, wherein the openings encompass between about 10% and about 90% of the total area of the substrate and an electrically conductive porous material bound to the substrate comprised of a electrically conductive component and a binding component.
Patent EP-0949302-A2 (EP)
Inventor: KOMAI EIJI
IPC: C09C3/12
Filed: 1999-03-31
Abstract: Provided is fine powder of hydrophobic titanium oxide,
which, when added to toner powder, makes the resulting toner
powder have high flowability and good electrification stability.
Also provided is an inexpensive method for producing it.
Titanium oxide, which is prepared by hydrolyzing a volatile
titanium compound of being in a high-temperature vapor-phase
condition, in the presence of a combustible or incombustible
gas, and has a BET specific surface area of from 55 to 150 m 2 /g
and an anatase/rutile crystal structure in a ratio of anatase
falling between 0.3 and 0.98, is processed for surface
modification with a silane coupling agent and/or a silicone
compound to produce fine powder of hydrophobic titanium oxide.
Patent EP-0947171-A2 (EP)
Inventor: JERGER THOMAS
IPC: A61B90/00
Filed: 1999-03-23
Abstract: The flexible metal probe, for an endoscope, has a nominal fracture point (A) at the transit between the probe head (1) and the leading part length (2) of the probe. The dia. of the leading section (2) of the probe is reduced steadily along a defined center length (3) of the probe, to an end section (4) of a constant dia. The dia. is steadily increased at the probe tip (5) to a larger dia.
Patent EP-0957318-A2 (EP)
Inventor: LIPINSKI JOHANN
IPC: F24D3/14
Filed: 1999-04-03
Abstract: The holder (6) suspends a grid-shaped, hoist support (4) which supports heating pipes (3) and has an L=shaped formation. In a working position the vertical link (6a) can be secured onto the reinforcement grid and the horizontal link (6b) can be engaged with a grid wire of the hoist support component. The horizontal link may be formed as a spiral for accommodation of the selected grid wire. At the free end of the vertical link, a deformable hook (6c) may be provided. Two reinforcement grids, an upper (2) and a lower (5) one, may be arranged in the concrete bed (1) of the ceiling and spacing baskets (7) are provided to support the upper reinforcement grid. The heating pipes (3) are arranged in a neutral zone so as to be secured to the hoist support component, which in turn are fixed with the aid of the hoist holders to the upper reinforcement grid.
Patent EP-0964135-A2 (EP)
Inventor: KONISHI TETSU
IPC: F01D5/02
Filed: 1999-05-26
Abstract: Steam turbine different material welded rotor
constructed by rotors of different materials being jointed
together by welding has strength of jointed portion increased
and inspection of jointed portion facilitated. In steam
turbine rotor wherein bearing portion rotor 1 and high
temperature portion rotor 2 are jointed at weld portion A,
the high temperature portion rotor 2 and low temperature
portion rotor 3 at weld portion B and the low temperature
portion rotor 3 and bearing portion rotor 4 at weld portion
C, cavity portions 5, 6 are formed in the weld portions B,
C, respectively. Inspection holes 7, 8 are also provided in
the weld portions B, C. The high temperature portion rotor
2 is made of high heat resistant 12Cr steel and other rotors
are made of low alloy steel wherein the rotor 1 is of 2·1/4
CrMoV steel and the rotors 3, 4 are of 3·1/2 NiCrMoV steel.
Thus, materials are less expensive and inspection of weld
portions becomes facilitated by the inspection holes 7, 8 and
the cavity portions 5, 6.
Patent EP-0992746-A2 (EP)
Inventor: BAN TAKASHI
IPC: F25B1/02
Filed: 1999-10-04
Abstract: An air conditioning system includes an compressor 101 having a driving chamber
110, a suction port 116 and a discharge port 121, a first passage 107 that connects the
discharge port 121 to the driving chamber 110 by opening a capacity control valve 140, a
second passage 105 that connects the driving chamber 110 to the suction port 116 and a
driving means 130 that can change the output discharge capacity of the compressor by
changing the pressure in the driving chamber 110. The refrigerant can be released from the
driving chamber 110 to the suction port 116 separately from the second passage 105 if the
driving chamber reaches a predetermined high-pressure state. 
     In such an air conditioning system, abnormally high pressure problems are overcome
that utilizes a hot gas bypass heater. In particular, heating performance is improved, because
high pressure refrigerant is not released from the hot gas bypass heater circuit into the cooling
circuit. Further, an excessively high-pressure state in the driving chamber 110 can be
prevented.
Patent EP-1017131-A2 (EP)
Inventor: PELOZA KIRK B
IPC: H01R4/18
Filed: 1999-11-22
Abstract: An electrical connector (66) is provided for terminating a coaxial cable (68) having at least an inner conductor (76) and an outer conductive shield (72). The connector includes a coaxial cable carrier (12) for receiving the coaxial cable and including a ground terminal (28), the carrier being in engagement with the conductive shield of the cable. A terminal module (10) includes an insulator (16) mounting a signal terminal (14). The module is assembled on the carrier (12) to form a subassembly (30) with the signal terminal (14) generally parallel to the ground terminal (28). A conductive shielding shell (32) receives the subassembly (30) with the conductive shell being in engagement with the coaxial cable carrier (12). A cover (44) is mounted on the shell (32) for holding the conductor (76) of the cable (68) in engagement with the signal terminal (14) of the terminal module (10).
Patent EP-1006480-A2 (EP)
Inventor: MAETTOE JUHANI
IPC: H04N1/52
Filed: 1999-11-24
Abstract: A method and equipment implementing the method for processing digital image
information. The image information consists of a bit stream comprising a first
set of successive source values (Dk), for which a corresponding output value
(Ek) can be determined. In the method it is read a source value (Dk), and it is
determined an output value (Ek) corresponding to the source value. Further, it
is determined a residual part (Dk,2) corresponding to the difference between
the source value and the output value; it is calculated the sum of said residual
part (Dk,2) and the next source value (Dk+1); said sum is used as the next
source value as a response to said sum being lower than or equal to a
predetermined threshold value (Dmax). The invention provides a fast colour
dithering method for such solutions in which the processing time of an image is
desired to be the shortest possible.
Patent EP-1035706-A2 (EP)
Inventor: LANGNER KLAUS DR
IPC: H04L29/06
Filed: 1999-11-27
Abstract: The method involves storing the serial number of a data transmission device in a non-volatile memory element, reading out the serial number of the communications software in the data transmission device and generating a user identity from the serial number using a defined algorithm. The serial number is transferred to a network segment requesting the user identity before the first access and the user identity is generated in the requesting segment using the same algorithm and stored in the user database.
Patent EP-1006261-A2 (EP)
Inventor: MATSUDA HISASHI
IPC: F02C7/18
Filed: 1999-11-30
Abstract: A gas turbine plant comprises an air compressor (21), a
gas turbine combustor (22) and a gas turbine (23), which are
operatively connected in series. In the gas turbine plant,
an air compressor shaft (26) is accommodated in the air
compressor and composed of discs (45) piled up along an axial
direction of the air compressor shaft, a gas turbine shaft (35)
is accommodated in the gas turbine and composed of discs (46)
piled up along an axial direction of the gas turbine shaft,
and an intermediate shaft (39) is interposed between the air
compressor shaft and the gas turbine shaft. At least one of
the discs of the air compressor shaft and the discs of the
gas turbine shaft are provided with bulged portions each
having approximately a hanging bell shape or trapezoidal
shape.
Patent EP-0985997-A2 (EP)
Inventor: SHIN TAKAHIRO
IPC: G06F1/16
Filed: 1997-07-03
Abstract: A thin structure information processing apparatus includes a body (1) which has a substantially planar structure and structure and accommodating therein at least a main board (2); a power supply board (3); a built-in battery (4); and a built-in hard disk drive (5). The main board, the power supply board, the built-in battery and the built-in hard disk drive are arranged in such a manner they are not imposed on each other with respect to a plane of the substantially planar structure.The main board (2) is provided with connectors (9) which project upward from the main board at positions away from the areas where a keyboard module (6) overlaps the main board (2).
Patent EP-1010600-A2 (EP)
Inventor: BACK WALTER
IPC: B61D47/00
Filed: 1999-12-15
Abstract: To load vehicles (2,3) on to railroad wagons (8), they are moved across the rail tracks (4) through a ramp (5) for loading and unloading. The vehicles (2,3) move on pallets (12) which are pushed on to the wagons (8) and remain in place during the journey together with their vehicles (2,3). While the pallets are being moved, they are guided by centering units between their end sides to slide accurately into the allocated space.
Patent EP-0915351-A2 (EP)
Inventor: FOOKS ELIK I
IPC: G01S17/04
Filed: 1993-12-30
Abstract: An operator interface for a photoelectric control unit
including a graphical display having a plurality of icons
corresponding to different control functions and a numerical
display for indicating parameter settings and operating margin
values. The operator interface allows the user to rapidly and
conveniently reconfigure the control unit for operation in a
number of different modes in accordance with a number of
different operational settings. Furthermore, the interface
provides information on the operating margin of the photoelectric
control unit which can be useful to the operator in aligning the
unit and in judging conditions under which the unit is operating.
Furthermore, the operator interface allows the user to select
different light pulse repetition rates and corresponding
operating ranges for the photoelectric control unit.
Patent EP-0950966-A2 (EP)
Inventor: NISHIYAMA TAMOTSU
IPC: G06F17/50
Filed: 1989-09-07
Abstract: A method of automatically and sequentially routing connection lines
between nodes of a graph representing a technical system, said diagram
comprising a plurality of regions each of which comprises a row or
column of nodes, whereby parts of each connection line are routed
according to predetermined routing sequences corresponding to routing
patterns, each pattern being determined based on the start and end
position of the said part.
Patent EP-0989798-A2 (EP)
Inventor: HUANG HSIN-HONG
IPC: B65G47/14
Filed: 1999-08-27
Abstract: There is disclosed herein an apparatus for bulk-feeding
electronic components which utilises magnetic force and a
rotating feeder tube to properly orient the components for
presentment to an automated pick-and-place machine. The
apparatus comprises: (1) a generally straight tube 10 having
a raised end 12, a lowered end 14, a longitudinal axis L-L,
and a generally cylindrical interior passage 16
therethrough; (2) a generally straight bar magnet 20
arranged beneath and proximate the tube 10, wherein the bar
magnet has a North pole-South pole axis N-S oriented
generally parallel with the tube longitudinal axis L-L; (3)
a receptacle 30 having first and second ends 32/34 and a
tapered throat 36 running therethrough, wherein the throat
extends from an enlarged inlet 38 defined in the first end
to a constricted outlet 39 defined in the second end, the
receptacle being disposed such that the inlet is elevated
above the outlet, the second end 34 of the receptacle being
disposed in rotatably slidable contact with the raised end
12 of the tube such that the constricted outlet 39 is placed
in communication with the tube interior passage 16 thereat;
and (4) means 40 for rotating the tube 10 about its
longitudinal axis L-L.
Patent EP-0987637-A2 (EP)
Inventor: MATSUMOTO KENTARO
IPC: G06F17/30
Filed: 1999-08-31
Abstract: A plurality of images and a feature of each of these
images are stored in one image file. An attribute
information area stores attribute information necessary to
read out and display the images stored in the image file.
A feature data area continuously stores features of the
images stored in the image file. An image data area
continuously stores image data of the images stored in the
image file. Since one image file has the attribute
information, the feature data area continuously storing the
features of all images, and the image data area continuously
storing all images, high-speed access to the image data and
simple management of the image data are realized.
Patent EP-1003351-A2 (EP)
Inventor: TATEMATSU KAZUHO
IPC: H05B3/14
Filed: 1999-11-17
Abstract: A ceramic heater (2) of required heating properties is
made available in that adjusting elements made solid in an
electric conductive element are added other than electric
conductive elements of an heating resistor (22) in a ceramic
heater (2). Accordingly, resistance temperature coefficient
is changed, not largely changing other properties of heating
materials. The heating resistor (22) may be used to a double
frame ceramic heater (2A), whereby deviations of baking
conditions may be made little to heighten adherence and avoid
breakage at grain boundaries
Patent EP-0979643-A2 (EP)
Inventor: ARNAUD PASCAL
IPC: A61K8/00
Filed: 1999-08-06
Abstract: Transferless make-up or care composition comprises a volatile hydrocarbon oil (I) and a synthetic wax (II) in a medium, where (II) has at least one hydroxy or carboxy functional group and has a melting point of 75-120 degrees C and Hansen solubility parameters such that: delta d = 15.5-18.5 J<0>.5/cm-1.5 and  delta a = 4.5-7.5 J<0>.5/cm-1.5, where  delta a is the square root of the sum of the squares of  delta p and  delta h.
Patent EP-1057359-A2 (EP)
Inventor: SALIN HANNU-PEKKA
IPC: H04W8/06
Filed: 1999-02-19
Abstract: The present invention relates to a mobile communication system comprising a mobile services switching centre (MSC2) and a visitor location register (VLR) and a home location register (HLR, HLR2), the information on particular subscriber stations being stored therein, and comprising means for transmitting a cancellation message (S1) to said visitor location register (VLR) for removing the subscriber information on a particular subscriber station from the visitor location register (VLR). To enable the connections of the mobile station to be disconnected, the visitor location register (VLR) comprises disconnection means (2) for transmitting a predetermined disconnection message (S2) to the mobile services switching centre (MCS2), and the mobile services switching centre (MSC2) comprises means for disconnecting an ongoing connection of the mobile station (MS) in response to said disconnection message.
Patent EP-1064015-A2 (EP)
Title: Peptides derives de recepteurs agissant en tant que modulateurs de l'activite de ces recepteurs
Inventor: OLSSON LENNART
IPC: G01N33/15
Filed: 1999-02-23
Abstract: La présente invention concerne des oligopeptides dont la séquence d'acides aminés correspond à un domaine extracellulaire de récepteur et qui présentent une analogie de séquence avec des peptides régulateurs d'antigènes MHC de classe I. Ces peptides favorisent ou remplacent la réponse physiologique d'un ligand se liant avec le récepteur correspondant. Ces oligopeptides sont utilisés dans le diagnostic et le traitement de maladies en rapport avec une réponse insuffisante ou inappropriée des récepteurs, ainsi que pour le criblage de médicaments candidats qui ont une incidence sur l'expression de surface des récepteurs. Une molécule réceptrice modifiée, dont la séquence correspondant au peptide régulateur a été modifiée ou supprimée, convient également pour le criblage de médicaments.
Patent EP-1000361-A2 (EP)
Inventor: VELZEN JEROEN VAN
IPC: H05B44/00
Filed: 1999-05-06
Abstract: Integrated voltage level indicator comprising a plurality of polymer LEDs between two contact leads, in which the number of luminescing LEDs and/or the intensity of the light in each LED is determined by the external voltage level.
Patent EP-1228056-A2 (EP)
Inventor: ROCK MICHAEL HAROLD
IPC: C07C255/56
Filed: 1999-10-25
Abstract: L'invention concerne un procédé de préparation de citaloprame consistant à faire réagir un composé avec de l'halogénure de 3-(N,N-diméthylamino)-propyle magnésium. Ce composé est représenté par la formule (IV), dans laquelle R représente alkyle C1-6, acyle, arylsulfonyle ou alkylsufonyle C1-6.
Patent EP-1236298-A2 (EP)
Inventor: CAO SIMON X F
IPC: H04B10/29
Filed: 1999-06-04
Abstract: L'invention concerne un système optique et programmable d'ajout/suppression de longueurs d'onde destiné aux réseaux optiques. Dans ledit système, un premier signal optique est généré sur la première boucle optique sous forme de pluralité de longueurs d'onde empruntant des trajets séparés, ladite génération se faisant dans le domaine optique; l'une des pluralités de longueurs d'onde est réfléchie et supprimée de la première boucle optique de façon à passer dans la seconde; des longueurs d'onde correspondantes sont ajoutées de la seconde boucle optique de façon à passer dans la première, la suppression et l'ajout se faisant dans le domaine optique; et les longueurs d'onde réfléchies et les longueurs d'onde ajoutées sont combinées de façon à générer un second signal. Le système de suppression et d'ajout de la présente invention permet d'assurer la compensation de dispersion, l'amplification de signal et la correction de gain nécessaires à la génération de la pluralité de longueurs d'onde, ainsi que la fonction de commutation nécessaire à la suppression et à l'ajout de longueurs d'onde, sans qu'il soit nécessaire de convertir le signal du domaine optique au domaine électrique puis de nouveau au domaine optique. Le système de l'invention est donc plus simple et moins coûteux à mettre en oeuvre que les systèmes classiques. Il présente en outre comme avantage le fait qu'il permet de diffuser et de contrôler individuellement l'ajout et la suppression de longueurs d'onde. Son caractère programmable diminue le nombre de multiplexeurs en longueur d'onde denses nécessaires et sa structure modulaire lui procure la souplesse nécessaire au passage à des systèmes plus complexes.
Patent MD-20140101-A2 (MD)
Title: Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer
Inventor: TREMBLAY GILLES BERNARD
IPC: A61P35/00
Filed: 2013-02-22
Abstract: The invention relates to medicine, particularly to oncology, and can be used to treat cancer.According to the invention, epidermal growth factor receptor (EGFR) expression and phosphorylation is increased in cancer cells treated with anti-clusterin antibodies. Such treatment is also accompanied with the reappearance of an epithelial phenotype of the cancer cell, as determined by an increased E-cadherin expression at the surface of cancer cells. Clusterin inhibitors may thus induce reversal of the epithelial to mesenchymal phenotype and restore sensitivity of cancer cells to EGFR inhibitors. Combinations of a clusterin inhibitor and an EGFR as well as their use in the treatment of cancer are thus provided in the present invention.