baber/WOPTO huggingface dataset:
Patent PT-981609-E (PT)
Inventor: ROLF WARTHOE PETER
IPC: G16B35/20
Filed: 1998-05-13
Abstract: The present invention relates to a two-step reverse transcription of DNA from RNA, wherein two types of reverse transcriptase enzymes are employed. The one type of reverse transcriptase enzyme having a temperature optimum at below 55 DEG C and the other type of reverse transcriptase enzyme having a temperature optimum above 55 DEG C, thereby obtaining cDNAs which are representatives of the entire gene, including the translated regions and at the same time performed effectively. <IMAGE>   <IMAGE>
Patent PT-1027695-E (PT)
Inventor: GOBOARDS INTERNATIONAL S A
IPC: G09F15/00
Filed: 1998-11-19
Abstract: A system and method for displaying advertising. A movable medium moves continuously and displays an image. An object is disposed in front of the movable medium. The movement of the image displayed on the movable medium in relation with the object creates the effect that the object is moving in relation to the image.
Patent PT-987783-E (PT)
Inventor: SMITH ROGER Q
IPC: H01M50/247
Filed: 1999-09-06
Abstract: In accordance with the present invention, an improved audio equipment is employed. The audio equipment comprises a main housing (11) and a receptacle assembly (50) for receiving a battery (60) via a connector (56) appropriate to contact the battery terminals. The receptacle assembly is flexibly connected to the main housing and preferably comprises a receptacle housing (55) on which the connector (56) is disposed and a flexible gasket (51) disposed between the receptacle housing and the main housing. Charger circuitry (43) for charging the battery can be fixedly connected to the connector (56). The flexible connection of the minimises shock to the battery pack (60) and the circuitry (43) if the audio equipment is dropped.
Patent PT-1064018-E (PT)
Inventor: HUDSON BILLY G
IPC: A61K38/39
Filed: 1999-03-26
Abstract: The instant invention provides methods and kits for inhibiting angiogenesis, tumor growth and metastasis, and endothelial cell interactions with the extracellular matrix, involving contacting the tumor or animal tissue with at least one isolated type IV collagen NC1  alpha  chain nonomer. In a specific embodiment of the invention, the isolated domain of type IV collagen comprises the NC1 ( alpha 1), ( alpha 2), ( alpha 3), or ( alpha 6) chain monomer, or protein constructs having substantially the same structure as the NC1 ( alpha 1), ( alpha 2), ( alpha 3), or ( alpha 6) chain monomer.
Patent PT-1089722-E (PT)
Inventor: ROVATI LUCIO C
IPC: A61K31/565
Filed: 1999-06-22
Abstract: The present invention refers to a transdermal patch for the release of Estradiol and at least one progestogen agent through the skin, comprising or consisting of an outer backing foil, a matrix and a protective liner wherein a) the Estradiol and the progestogen agent(s) are present in the matrix in an oversaturated solution, b) the matrix contains 1 to 5 wt% activated SiO2, and c) the matrix has a moisture content of less than 0.7 wt.-%. The patch can be used for hormonal replacement therapy.
Patent PT-1104417-E (PT)
Title: Improved omeprazole process and compositions thereof
Inventor: ANOUSIS NICK
IPC: A61K31/44
Filed: 1999-08-06
Abstract: The present invention describes an improved process for the preparation, isolation, and purification of the anti-ulcer agent omeprazole whereby the sulfide precursor pyrmetazole is reacted subsurfacely with exactly one molar equivalent of meta-chloroperoxybenzoic acid in methylene chloride or toluene solution; residual organic solvent is removed from the aqueous layer by vacuum distillation; crude product is obtained by reactive crystallization with an alkyl formate and seeding; and pure product is isolated by recrystallization in methanol-water containing aqueous NaOH by subsurface addition of aqueous acetic acid to pH 9.0, seeding, filtration, washing, and drying. Compositions of omeprazole containing no chromatographically detectable levels of residual non-alcoholic organic reaction solvent are also described.
Patent SG-106287-G (SG)
Title: Gear train mechanism for a watch
IPC: G04B27/00
Filed: 1987-12-05
Abstract: A gear train mechanism for a watch comprising a plate (23, 24); a tubular member (14) mounted in said plate (23, 24); a gear train bridge (2); a seconds gear (7) which is rotatably mounted in the gear train bridge (2) and which is adapted to drive a seconds hand (not shown); a further gear (8) driven by the seconds gear (7); a centre gear (9) adapted to drive a minutes hand (not shown) and driven by the further gear (8), the centre gear (9) being provided with a support shaft (9b) which is rotatably mounted within the tubular member (14); a minute gear (20) driven by the centre gear (9); an hour gear (11) which is driven by the minute gear (20) and which is adapted to drive an hour hand (not shown), the hour gear (11) being rotatably mounted on the tubular member (14); and the centre gear (9) having an axial bore (9c) therethrough within which a shaft portion (7d) of the seconds gear (7) is rotatably supported at one region (7a) only. <IMAGE>
Patent SG-110393-G (SG)
Title: Motor vehicle lift
Inventor: ROSSATO ERIDE
IPC: B66F7/08
Filed: 1993-09-27
Abstract: The motor vehicle lift has a pair of base longitudinals (1) with a pair of hinged uprights (2) and a second pair of uprights (4) hinged between these and the longitudinals. A pair of vehicle lift runways (6) are hinged to the first uprights. A pair of actuators (17) vary the angle of the uprights to raise the lift. A pair of arms (15,15') are interposed between the first uprights and the portion (8) of the runways (6) hinged to them. The lower ends of one pair of uprights can slide w.r.t. the longitudinals.
Patent IE-820028-L (IE)
Title: N-(3'-(p-TERT-BUTYLPHENYL)-2'-METHYLPROP-1'-YL)-PIPERIDINE¹DERIVATIVES.
IPC: C07D211/22
Filed: 1982-01-08
Abstract: 1. Claims for the contracting states : BE, CH, LI, DE, FR, GB, IT, LU, NL, SE An N-(3'-(p-tert.-butylphenyl)-2'-methyl-prop-1'-yl)-piperidine derivative of the general formula  see diagramm : EP0056461,P6,F5 where R is acetyl or propionyl, or a salt thereof. 1. Claims for the contracting state : AT A fungicide containing an N-(3'-(p-tert.-butylphenyl)-2'-methyl-prop-1'-yl)-piperidine derivative of the general formula  see diagramm : EP0056461,P6,F6 where R is acetyl or propionyl, or a salt thereof.
Patent IE-830059-L (IE)
Title: Preparation of phosphine oxide derivatives
IPC: C07F9/11
Filed: 1983-01-11
Abstract: PURPOSE:To convert the titled compound prepared by the use of phosphine as a desulfurizing agent, to oxide which can easily be made pollution-free, at a low cost, without using odorous raw materials, under mild conditions, by reacting phosphine sulfide with a chlorination agent and water. CONSTITUTION:A phosphine sulfide (e.g. triphenylphosphine sulfide) is mixed with a mixture of isopropanol, etc. and an aqueous solution of sodium bicarbonate. A mixture of a chlorination agent (e.g. sodium hypochlorite, etc.) and water is added dropwise to the mixture at 15-20 deg.C, and the obtained mixture is made to react at 20 deg.C for about 1.5hr under stirring. After the completion of the reaction, the organic layer composed of isopropanol, etc. is separated and diluted with water to crystallize phosphine oxide. The crystals are filtered, washed with water, and dried to obtain the objective compound.
[JP58121295A]
Patent IE-860198-L (IE)
Title: Cell corrosion reduction
IPC: H01M6/04
Filed: 1986-01-23
Abstract: Gassing is significantly reduced in electrochemical cells having anodes of metals, such as zinc, by reducing the number of grains in the particles of the polycrystalline metal to at least a third of the original number of grains and thereafter using the metal in the formation of the cell anode. Such grain number reduction is effected by heat treatment of the anode metal at a temperature below that of the melting point of the metal. Corrosion is further reduced with such reduced grain number particles and particularly with single crystal particles by the addition of small amounts of a gas inhibiting surfactant, for example, an organic phosphate inhibitor such as RA600 from GAF Corp. to the cell. Alternatively, or in addition, corrosion is reduced by prealloying the metal particles with small amounts of one or more of indium, thallium, gallium, bismuth, cadmium, tin and lead prior to reduction of the number of grains or the formation of the single crystal particles. A synergistically lowered rate of corrosion and cell gassing is obtained even with reduction of mercury content.
[GB2170946A]
Patent IE-38825-L (IE)
Title: Stabile viral preparation
IPC: A61K39/25
Filed: 1974-02-04
Abstract: New stabilizing compositions for cell-free viruses comprising a buffered solution of polyvinylpyrrolidone, sucrose, glutamate and a chelating agent. The compositions stabilize the viruses during their extraction from the cells to which they are associated and during the lyophilization and/or storage of the cell-free viruses. The compositions are useful for the preparation of cell-free virus vaccines.
[US3915794A]
Patent IE-37303-L (IE)
Title: Firelighter compositiions
IPC: C10L11/04
Filed: 1972-02-28
Abstract: 1378516 Solid fuel KAYFORD MFG CO Ltd 19 Jan 1972 [5 April 1971] 8711/71 Heading C5G A solid fuel firelighter comprises flowable particles comprising a synthetic polymeric matrix in which is dispersed hydrocarbon fuel, the predominant proportion of the particles having a particle size less than  inch. The preferred hydrocarbon fuel is kerosene, part of which may be replaced with paraffin wax, polypropylene or polyethylene. Also cellulosic material, e.g. sawdust, and sugar, may be included. The matrix is urea-formaldehyde resin. Nitro compounds, nitrates, peracids, phosphates and peroxides are included to improve burning.
[GB1378516A]
Patent IE-44519-L (IE)
Title: Detoxicating rapeseed meal
IPC: A23L11/30
Filed: 1977-02-04
Abstract: The content of repossed meal is reduced by treating the meal immediately after it leaves the extractor with 1-8%, preferably 2-4%, of an at ambient temperature non-volatile, alkaline substance; raising the moisture content of the meal to 8-25% and thereafter steaming the meal less than 30 minutes. The described treatment allows the incorporation of greater amounts of repossed meal in animal feedstuffs without thyrotoxic effects occurring.
[CA1091085A]
Patent IE-810611-L (IE)
Title: Ultrasonic length measurement technique
IPC: G01B3/18
Filed: 1981-03-19
Abstract: A distance R to be measured is derived by measuring the spacing xm between a fixed transmitter Tx and a movable receiver Rx, and comparing this with the reference spacing xref between a fixed transmitter Tx' and receiver Rx. Each spacing is measured by passing a large number of pulses sequentially from receiver to transmitter through a.coupling medium, the receipt of one pulse triggering transmission of the next. The spacing is derived from the time Ttaken to pass n pulses; preferably n is fixed and T is measured.
Patent IE-850669-L (IE)
Title: Notching an optical fibre
IPC: G02B6/00
Filed: 1985-03-15
Abstract: Optical fiber (2) is scribed to produce a notch (4) by means of a fiber holder (10), a circular scribing edge (18) which is spaced from the fiber holder by a first distance (L1), a fiber deflector (14) which is spaced from the fiber holder by a second distance (L2) and which is movable laterally to deflect the fiber by a third distance (L3). When the fiber (2) is deflected by the fiber deflector, the fiber is brought into contact with the circular scribing edge (18) and is moved along the edge for a short distance. The first, second, and third distances are selected to produce a scribing force which is within a predetermined range.
[EP0155794A1]
Patent IE-860669-L (IE)
Title: Thieno-imidazoles
IPC: C07D495/04
Filed: 1986-03-13
Abstract: A process for the preparation of a thieno-imidazole derivative having the general formula:-werein R is -(CH<sub>2</sub>)<sub>4</sub>CH<sub>3</sub>, -(CH<sub>2</sub>)<sub>3</sub>OR<sup>1</sup> or -(CH<sub>2</sub>)<sub>5</sub>0R<sup>1</sup>, R' is (C<sub>1</sub>-C<sub>6</sub>) alkyl, -(CH<sub>2</sub>)<sub>4</sub>CN or -(CH<sub>2</sub>)<sub>4</sub>COOR<sup>2</sup> and R<sup>2</sup> is (C<sub>1</sub>-C<sub>6</sub>) alkyl or phenyl; characterized in that a compound of the formula:-wherein R is as defined above, is reacted with an epoxy compound of the formula:-wherein R<sup>3</sup> is hydrogen, methyl or-CH<sub>2</sub>OH; in the presence of an alkanol.In particular this process may be used to prepare descarboxybiotin which is a useful intermediate for the preparation of d - biotin.
Patent FI-850282-L (FI)
Inventor: SMITS PETER CAROLUS CORNELIS
IPC: C07H7/027
Filed: 1985-01-22
Abstract: Preparation of 2-keto-aldonic acids, e.g., 2-keto-gluconic acid, by oxidizing an aldose, e.g. glucose, or aldonic acid in aqueous solution with molecular oxygen. Use is made of a pletinum catalyst together with a catalytic amount of lead and/or bismuth and/or a compound thereof. The pH of the solution is in the range of from 4 to 12 and preferably in the range of from 7 to 9. The reaction may be carried out at a temperature in the range of 0 to 200°C and preferably in the range of from 25° to 80°C.
Patent IE-821010-L (IE)
Title: Inflammable gas detector device
IPC: G08B17/10
Filed: 1982-04-29
Abstract: The detector (R) is formed of a spiral of thin platinum alloy wire enclosed in a Davy cage of fine metallic grids to prevent flame propagation in the event of ignition within. It is connected in a bridge circuit with potentiometer (R3) and two fixed resistor (R2, R4), supplied with rectified AC from a series transistor (T1) and Zener diode stabiliser (Z1). The unbalance of the bridge is monitored by a differential amplifier (Ad) which controls a low-frequency tone generator (IC2). When the threshold of unbalance is exceeded due to a concn. of gas within the detector, an alarm is given by an electroacoustic device (TA). A standby battery and delay circuit may be provided to ensure operation following failure of the AC supply or rectifier.
[EP0065497A1]
Patent IE-34536-L (IE)
Title: Acylaminopenicillanic acids
IPC: C07D499/44
Filed: 1970-09-18
Abstract: 1285790 Acylaminopenicillins FARBWERKE HOECHST AG 28 Sept 1970 [27 Sept 1969 (2)] 46107/70 Headings C2A andC2C Novel acylaminopenicillanic acids of Formula I wherein R<SP>1</SP> and R<SP>2</SP> are the same or different and are hydrogen or C 1 to C 5 alkyl or together form an optionally substituted alkylene group linking the nitrogen atoms, R<SP>3</SP> is hydrogen or C 1 to C 5 alkyl, A is an optionally substituted phenylene or thienylene group and B is oxygen or a chemical bond, and salts thereof, are prepared by reacting 6-aminopenicillanic acid or a salt thereof with a carboxylic acid of Formula II wherein R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP>, A and B are as defined above or an N-acylating derivative or salt thereof. The groups R1, R<SP>2</SP> and R<SP>3</SP> preferably contain a total of not more than 6 carbon atoms. When R<SP>1</SP> and R<SP>2</SP> form an alkylene group, this may be substituted, e.g. by C 1 to C 5 alkyl groups which may be closed into a ring and this ring may include a hetero atom. A is preferably 1,4-phenylene or 2,5-thienylene and may be substituted, e.g. by alkyl, alkoxy and/or halogen. The reaction may be carried out in water, preferably together with a water-miscible solvent, at pH 6-9 and at ambient temperature or below; an acid-acceptor, e.g. NaHC0 3 or triethylamine, is preferably present in the medium. The product may be isolated by simply lyophilizing the reaction mixture to give the penicillin in the form of a crude mixture with salts (e.g. NaCl) formed as by-products, which may be used therapeutically without purification providing the salts are non-toxic. It is purified by re-crystallization from concentrated aqueous solution. The acid chlorides of 4-amidinophenylacetic acid, 4-amidmophenoxyacetic acid and 4-(2- imidazolinyl)-phenoxyacetic acid as their hydrochloride salts are prepared by reacting the acid with thionyl chloride. Pharmaceutical compositions having antibacterial activity against gram-positive and gramnegative bacteria comprise an acylaminopenicillanic acid of Formula I as defined above or a physiologically tolerable salt thereof together with a pharmaceutical carrier.
[GB1285790A]
Patent IE-801332-L (IE)
Title: Fermenter for eukaryotic cells
IPC: C12M3/00
Filed: 1980-06-26
Abstract: 1. Process for the surface culture of nucleated cells and for the recovery of cell culture-dependent substances from the cells thus obtained, characterized in that coils, saddle-shaped members, spirals or wire spirals each made of metal are used as the culture surface, these objects retaining less than 8 % of the medium, based on the free volume, after the aqueous culture medium has run out, and at the same time the ratio of the surface area of the culture surface to the free volume is between 20:1 and 5:1 cm**-1.
[EP0021257A1]
Patent IE-44289-L (IE)
Title: (2-oxo-imidazolidin-1-yl-carbonyl (or thiocarbonyl)amino)-¹acetamido penicillins
IPC: A61P31/04
Filed: 1976-06-23
Abstract: The title compounds correspond to the formula I; the symbols used are defined in Claim 1. The compounds are obtained by acylation of the optionally silylated amino group of the antibiotic derivatives of the formula II with a derivative of a carboxylic acid or thiocarboxylic acid of the formula III to form a -CE-NH linkage (E = oxygen or sulphur). Protective groups which are present are subsequently eliminated, and the beta -lactam compounds are finally obtained as free acids or as non-toxic salts. The compounds belong to the penicillin and cephalosporin series and can accordingly be used as antibiotics and as animal feed additives. They have a broad spectrum of action while being well tolerated. <IMAGE>
[GB1538284A]
Patent IE-871374-L (IE)
Title: Variants of alpha-one-antitrypsin.
IPC: C12N15/15
Filed: 1987-05-26
Abstract: The invention relates to the variant of human alpha1-antitrypsin of formula: (Ala357, Arg358) alpha1-AT. This compound is useful as a kallikrein inhibitor.
[US4973668A]
Patent IE-35783-L (IE)
Title: Molecular complexes
IPC: A23K1/16
Filed: 1971-10-29
Abstract: 1356473 Medicated &c animal feeds HETEROCHEMICAL CORP 28 Oct 1971 [6 Nov 1970] 50163/71 Heading A5B [Also in Division C2] An animal food composition containing e.g. amino acids and vitamin active compounds comprises a molecular complex of (a) an aliphatic, aromatic or heterocyclic amine e.g. 2-hydroxy-4, 6-dimethylpyrimidine and (b) a bis-(5-nitrofurfurylidene)-acetone guanyl hydrazone or addition salt thereof of general formula (1) or (2) in which R 1 is H, halogen or C 1-4 alkyl; R 2 is H or C 1-4 alkyl; X is a mono-, di- or tri-basic acid; n is 1, 2 or 3; n is 1, if x is monobasic, n is 1 or 2 if x is dibasic and n is 1, 2 or 3 if x is tribasic. The complexes promote. growth and anti-infection properties.
[GB1356473A]
Patent IE-46038-L (IE)
Title: Blistered silicate material
IPC: C03C12/00
Filed: 1977-07-25
Abstract: A process for the manufacture of a blistered silicate material having a high content of wollastonite and a low content of cristobalite and containing up to 30 to 40 percent by volume of fine blisters the size of a majority of which are 0.1 to 1mm with a substantial proportion being below 0.1mm wherein raw materials for the silicate material are introduced partly at the upper end of an inclined rotary kiln and partly at the lower end of the rotary kiln, whereby the materials will be distributed in the burning zone and melt.
[US4119434A]
Patent IE-821690-L (IE)
Title: Leaf spring
IPC: B60G11/12
Filed: 1982-07-14
Abstract: A fibre reinforced composite leaf spring is provided at its end with an end fitting for attachment to a rigid part of a vehicle. The end fitting 11 comprises an attachment member which fits snugly within an arcuate recess defined by a terminal portion of the spring. A sheet metal clamping member surrounds and reinforces the attachment member and recess and is rivetted or otherwise fastened to the leaf spring at a position remote from its terminal portion. The terminal portion of the spring extends around the attachment member at least beyond a position at right-angles to the longitudinal axis of the spring.
Patent IE-881843-L (IE)
Title: Tool guidance system for forming machine
IPC: B21D37/08
Filed: 1988-06-17
Abstract: Tooling system for a forming machine has a continuous guide passageway in which first and second tooling assemblies are contained for movement towards and away from each other. The passageway has passageway surfaces which serve as bearing and guiding surfaces for the tooling assemblies. Each of the tooling assemblies has a ram member and a tool holder mounted on the ram member. Additionally, a face plate is provided on one of the tooling assemblies at the leading end thereof and is movable relative to the leading end between a retracted position and an extended position. When in its extended position, it is spaced from the ram so that tools, such as punches have their ends in openings in the face plate. When the tooling assemblies move against strip material positioned therebetween, the punches or similar tools move from the face plate and perform operations on the strip. The face plate then serves as a stripper plate during reverse movement of the ram. The pilot pins are separately actuated by an external actuator but are carried in one of the ram assemlies.
[US4819476A]
Patent IE-832141-L (IE)
Title: Opthalmic lens having diffractive power
IPC: A61F2/16
Filed: 1983-09-13
Abstract: An ophthalmic lens incorporates a transmission hologram which has negative diffractive power and introduces positive longitudinal chromatic aberration to add to the natural longitudinal chromatic aberration of the human eye, thereby reducing the need to accommodate. The lens also has refractive power to balance the diffractive power or to give a desired overall or residual power.
[US4641934A]
Patent IE-822281-L (IE)
Title: Microbial expression of dna sequences
IPC: C12P21/00
Filed: 1982-09-17
Abstract: Microbial expression of an exogenous polypeptide may be inefficient if the messenger RNA has secondary structure (due to complementarity of spaced regions of the molecule) which impedes interaction with a ribosome. The occurrence of such structure can be predicted. The degeneracy of the genetic code gives freedom to alter the nucleic acid composition of the cDNA to eliminate harmful secondary structure of the mRNA. For example, bovine growth hormone (BGH) is poorly expressed by E. coli transformed with a recombinant plasmid containing the natural BGH gene. The corresponding mRNA has complementary regions at 46-51 and 73-78. Therefore a plasmid pBGH 33-4 was constructed containing a BGH gene whose upstream portion was synthesized (making use of plasmid pHGH 207-1 which contains an efficiently expressible gene for the closely related human growth hormone) so as not to cause the troublesome complementarity. E. coli transformed therewith produced BGH with a yield of better than 10<5> copies per cell.
Patent IE-802314-L (IE)
Title: Pharmaceutical injectable composition and two-pack container
IPC: A61K31/43
Filed: 1980-11-07
Abstract: A pharmaceutical composition for injection which comprises an aqueous sterile solution of a penicillin or salt thereof and from 1 to 10% of benzyl alcohol, a two-pack container or two-part syringe wherein one pack or part contains a penicillin or salt thereof in the form of a dry powder and the second pack or part contains an aqueous solution of benzyl alcohol, such that mixing the contents of the two packs or parts produces an aqueous solution of the penicillin and from 1 to 10% of benzyl alcohol, and a two-pack container or two-part syringe wherein one pack or part contains a penicillin in a solid free acid form, and the second part contains an aqueous solution of benzyl alcohol and substantially one equivalent of a basic pharmaceutically acceptable salt, such that mixing the contents of the two packs or parts produces an aqueous solution of a salt of the penicillin and from 1 to 10% of benzyl alcohol.
[US4518606A]