baber/WOPTO huggingface dataset:
Patent NZ-573187-A (NZ)
Title: Circulating tumor cell assay for predicting efficacy of 1gf-1r antagonist therapy
Inventor: PACCAGNELLA MARIA LUISA
IPC: G01N33/50
Filed: 2007-05-29
Abstract: Disclosed is a method for predicting efficacy of IGF-1R antagonist therapy in a patient, comprising the steps of: a) preparing a sample wherein a biological specimen derived from blood from the patient is mixed with a ligand that reacts specifically with tumor cells, to the substantial exclusion of other sample components, so as to obtain a cell population enriched for tumor cells; b) contacting the enriched cell population with an anti-cytokeratin antibody; c) contacting the enriched cell population with an antibody to insulin-like growth factor receptors (IGF-1R) on cells; and d) determining the presence of cells bound by both the anti-cytokeratin antibody and the anti-IGF-1R antibody; wherein the presence of cells bound by both antibodies is predictive of efficacy of IGF-1R antagonist therapy in the patient.
Patent NZ-573576-A (NZ)
Title: Benzimidazoles and their use for the treatment of diabetes
Inventor: PLOWRIGHT ALLEYN THOMAS
IPC: A61K31/4245
Filed: 2007-06-06
Abstract: Disclosed are compounds of formula (I), wherein the substituents are as defined in the specification, and processes for their preparation. The compounds inhibit acetyl CoA:diacylglycerol acyltransferase (DGAT1) activity and are useful in the treatment of type II diabetes, insulin resistance, impaired glucose tolerance and obesity in warm-blooded animals.
Patent NZ-579286-A (NZ)
Title: A spring biased guard for covering the access or pick holes in a manhole cover
Inventor: THOMPSON TINA
IPC: E02D29/14
Filed: 2008-02-05
Abstract: Disclosed is a manhole cover having a pick hole guard coupled to a bottom surface of the manhole cover. The pick hole guard includes a movable guard member and a base. A biasing member is attached to the base and to the movable guard member for biasing the movable guard member toward a pick hole of the manhole cover. The base is positioned outside of the pick hole.
Patent NZ-581459-A (NZ)
Title: Solid formulations of pyrazole-carboxamide arthropodicides
Inventor: GREEN JOHN HENRY
IPC: A01P7/00
Filed: 2008-06-20
Abstract: Disclosed are solid arthropodicide / biocidal compositions which comprise by weight: (a) from 0.3 to 100% of a particulate component comprising porous particles of a solid carrier (such as powders of calcium silicate, diatomaceous earths, bentonite, kaolin and attapulgite clays), the particles are infiltrated / adsorbed with a mixture comprising (i) one or more carboxamide arthropodicides of Formula 1, N-oxides, and salts thereof; and (ii) a surfactant constituent comprising one or more surfactants selected from the group consisting of alkylbenzenesulfonic acids and their salts, alkylpolyglycosides, hydroxyalkylcelluloses, ethylene oxide-propylene oxide block copolymers, vinylpyrrolidone polymers, ethoxylated sorbitan esters, ethoxylated sorbitol esters and acrylic graft co-polymers, such that the surfactant suppresses crystallization of the one or more carboxamide arthropodicides; (b) from 0 to 50% of a surfactant component having dispersing and wetting properties; and (c) from 0 to 99.7% of one or more additional formulating ingredients; wherein the substituents for the compound of formula (I) are: X is N, CF, CCl, CBr or Cl; R1 is CH3, Cl, Br or F; R2 is H, F, Cl, Br or cyano; R3 is F, Cl, Br, haloalkyl or haloalkoxy; R4a is H, alkyl, cyclopropylmethyl or 1-cyclopropylethyl; R4b is H or CH3; R5 is H, F, Cl or Br; and R6 is H, F, Cl or Br;. Of particular importance are formulations wherein the compound of formula (I) is selected from 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyI]phenyI]-1H-pyrazole-5-carboxamide or 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide.
Patent NZ-589390-A (NZ)
Title: Methods and compositions for oral administration of exenatide
Inventor: KIDRON MIRIAM
IPC: A61K31/22
Filed: 2009-05-03
Abstract: Disclosed is a composition comprising an exenatide, a protease inhibitor, and an omega-3 fatty acid, wherein said composition is an oral pharmaceutical composition, and wherein said protease inhibitor is selected from the group consisting of soybean trypsin inhibitor, AEBSF-HCI, (alpha) 1-antichymotypsin, antipain, (alpha)-1-antitrypsin ([alpha] 1-proteinase inhibitor), 4-amidinophenylmethane sulfonyl-fluoride, aprotinin, benzamidine-HCl, chymostatin, leupeptin, a-(2-Aminoethyl)-benzenesulfonyl fluoride hydrochloride), phenylmetþl sulfonyl fluoride, 1-Chloro-3-tosylamido-7-amino-2-heptanone HCI, 1-Chloro-3-tosylamido-4-phenyl-2-butanone, Ovomucoid, pepstatin, and iodoacetate for treating diabetes mellitus.
Patent NZ-590638-A (NZ)
Title: MACROCYCLIC QUINOXALINE COMPOUNDS AS Hepatitis C Virus NS3 PROTEASE INHIBITORS
Inventor: HARPER STEVEN
IPC: A61K38/06
Filed: 2009-07-17
Abstract: Provided is a macrocyclic quinoxaline compound of Formula (I), which is a hepatitis C virus NS3 protease inhibitor. The compound can be used in medicaments to treat HCV patients.
Patent NZ-593017-A (NZ)
Title: Piston assembly for positioning lumen in an osmotic delivery system having groove to retain elastomeric O-ring
Inventor: ALESSI THOMAS R
IPC: A61M31/00
Filed: 2007-08-08
Abstract: An osmotic delivery system comprising a piston assembly (400) is disclosed. The body of the piston assembly (400) is constructed and arranged for positioning in the lumen. The body is made of a selected group of polymeric material that is resistant to leaching in the presence of a selected group of organic solvents. The body of the piston assembly (400) comprises one or more concentric grooves. Each groove is formed to retain an elastomeric O-ring (402, 404) that is capable of engaging and sealing against the interior wall of the reservoir.
Patent NZ-593707-A (NZ)
Title: Lightweight plastic composite manhole cover
Inventor: BREBNER DONALD REID
IPC: E02D29/14
Filed: 2011-11-15
Abstract: A moulded plastic inspection cover or manhole lid for underground services such as electrical cables or wires , telephone and video communications fibres, or traffic signals, cast or formed in one homogenous piece with a continuous top section with a moulded pattern and a continuous or semi-continuous bottom section formed by plurality of intersecting vertical webs in longitudinal, transverse and diagonal alignments, and side edge cavities on all or some sides. The cover is generally rectangular or circular in shape. A centralised load on the cover is transferred to the reinforced peripheral edge or rim via the intersecting ribs. An alternative form has the side cavities extending to the centre of the lid forming a top and bottom sheet or plate or skin with connecting webs. The cover can be locked or securely fastened to a supporting socket or ring.
Patent NZ-593777-A (NZ)
Title: Method for performing curriculum planning
Inventor: RITTER GREG
IPC: G06Q10/00
Filed: 2006-04-12
Abstract: A method for performing curriculum planning involving one or more 5 organizational levels within a multi-level institution is disclosed. The method comprises receiving first goals relating to a first organization level of the institution; receiving second goals relating to a second organizational level of the institution; with a processor determining a first respective alignment that indicates which, if any, of a plurality of courses are aligned to at least one of the first and second goals; generating a mapping of the first respective alignment, and graphically presenting the mapping to a user.
Patent NZ-595563-A (NZ)
Title: A communications process, device and system
Inventor: DONAGHEY ANDREW PAUL
IPC: H04W4/70
Filed: 2010-03-31
Abstract: 595563 A communications system and method for controlling and interrogating a network of distributed remote units are disclosed. The system comprises a network management server for requesting and serving data associated with the remote units; concentrators for communicating with the network management server and communicating with respective remote units using respective communications protocols based on properties data maintained at the concentrators representing state and communications parameters associated with each remote unit; and remote units for serving properties data and message data to a concentrator and receiving data, including application files and service level data. The properties data of the remote units represents profiles of the remote units and devices installed with or communicating with the remote units, and the profiles. Each profile includes communications parameters and device parameters and the communications parameters represent the communications protocols and associated equipment the respective remote unit supports. The remote units can include a meter for measuring usage of a resource at a customer’s premises and a microengine for maintaining the properties data. The properties data can includes at least one of: (i) measurement data representing measurement of usage of the resource at the customer’s premises; (ii) configuration data representing configuration of the remote unit; (iii) data representing a meter reading schedule; (iv) data representing demand side management profile information; (v) data representing supported communications protocols the microengine can use for the microengine to concentrator, microengine to microengine and microengine to meter links and properties per protocol parameters; (vi) data representing configuration of meters and microengines with a 30 communications connection to the remote unit; (vii) data representing carbon footprint information; and (viii) tariff data representing a tariff associated with usage of the resource.
Patent NZ-597283-A (NZ)
Title: Controlled release formulations
Inventor: ANDERSEN CHRISTINE
IPC: A61K9/20
Filed: 2010-06-23
Abstract: 597283 Disclosed herein is a pharmaceutical composition for use in the treatment of pain in an individual in need thereof, comprising: a matrix composition comprising: an active drug substance, which is an analgesic, such as morphine, oxycodone, hydrocodone, hydromorphone, norhydrocodone oxymorphone, noroxycodore, or morphine-6-glucuronode; and at least one polyglycol having a molecular weight of at least 20,000 daltons, such as polyethylene glycol, polyethylene oxide or a poloxamer said matrix composition having a cylindrical shape optionally with tapered end(s), the length of said matrix being in the range of 7.5 to 15 mm, said matrix being surrounded by a coating having one or two openings exposing at least one surface of said matrix, said coating being substantially impermeable to an aqueous medium, wherein said composition is formulated for continued administration within the range of 20 to 28 hours interval between individual administrations.
Patent NZ-603030-A (NZ)
Title: A central tube type optical fibre micro-cable with grooves in outer sheath
Inventor: RUAN YUNFANG
IPC: G02B6/036
Filed: 2012-10-15
Abstract: 603030 A central tube type optical fibre micro-cable is disclosed. The cable includes an outer sheath (4) with a loose polycarbonate (PC) tube (2) disposed in the outer sheath (4). Optical fibres or optical fibre bundles (1) can be inserted within the loose tube. The outer sheath (4) includes a plurality of circumferentially spaced longitudinally extending grooves and ridges to assist pneumatic installation by blowing.
Patent NZ-603875-A (NZ)
Title: Methods and arrangements for reducing the signalling overhead in a wireless communication system using carrier aggregation
Inventor: BALDEMAIR ROBERT
IPC: H04W28/06
Filed: 2011-06-21
Abstract: Disclosed is a method in a mobile terminal for processing downlink control information. The method includes receiving, at a mobile terminal capable of receiving multiple component carriers, downlink control information on a component carrier. The downlink control information comprises a bit field allocated for a transmit power control command. If the bit field comprises one or more bits that are not used for a transmit power control command, the method includes interpreting the meaning of the bits not used for a transmit power control command depending on an ACK/NACK feedback mode the mobile terminal is configured with. If the mobile terminal is configured with a full ACK/NACK feedback mode, the bits are interpreted as a trigger to transmit aperiodic sounding reference signals; if the mobile terminal is configured with an ACK/NACK bundling feedback mode, the bits are interpreted as an indication of a number of downlink assignments the mobile terminal should have received or will receive. This eliminates the requirement to separately signal a Downlink Assignment Indication (DAI) to the mobile terminal.
Patent NZ-612088-A (NZ)
Title: A wind turbine
Inventor: HASSENFLU JOHN FRANZ
IPC: F03D7/06
Filed: 2011-11-22
Abstract: A vertical axis wind turbine includes a vertical shaft (4) supporting a rotor hub (3) that includes plurality of blades which extend from the hub. Each blade includes a top portion with a leading edge and trailing edge and a bottom portion with a leading edge and trailing edge. The top and bottom portions are connected along at least a portion of their respective leading edges to form a leading edge of the blade. The respective trailing edges of the top and bottom portions diverge. The root of each blade is oriented at an angle to a radial direction from the shaft (4) and at least a portion of each blade is swept back.
Patent NZ-617944-A (NZ)
Title: Methods and compositions for modulating gene expression using components that self assemble in cells and produce rnai activity
Inventor: SMITH LARRY J
IPC: C12N15/11
Filed: 2012-04-20
Abstract: Disclosed is an in vitro screening method for selecting an antisense strand binding site on a ribonucleic acid target of interest, said method comprising; (i) identifying a site on said target that is available for antisense strand binding using an antisense oligonucleotide; (ii) obtaining a set of a first and a second oligonucleotide with sequences capable of forming a duplex or a set of a first and a second oligonucleotide that are not complementary to each other but which are capable of forming a duplex with a third strand where in at least one strand is complementary to the site identified as available for binding in (i); (iii) modifying said oligonucleotide strands to increase their stability and activity; (iv) contacting a cell expressing said target with said first oligonucleotide strand or said two non-complementary strands and providing a suitable amount of time for said strand(s) to enter said cell; (v) contacting said cell with said second or said second and third oligonucleotide strands not complementary to each other but complementary to a strand in (iv) and; (vi) determining the expression of the target sequence as compared to the expression of the target sequence without step (iii).
Patent NZ-627251-A (NZ)
Title: Combination of (3s,3s’) 4,4’-disulfanediylbis(3-aminobutane 1-sulfonic acid) and a second antihypertensive agent
Inventor: BALAVOINE FABRICE
IPC: A61P9/12
Filed: 2012-12-21
Abstract: The present invention relates to a pharmaceutical composition comprising, in at least one pharmaceutically acceptable support or vehicle, a combination of (3S,3S’) 4,4’-disulfanediylbis(3-aminobutane 1-sulfonic acid) or a pharmaceutically acceptable salt or solvate thereof and a second active ingredient selected from the group consisting of angiotensin I converting enzyme inhibitors and angiotensin II receptor type I antagonists. Said composition isparticularly useful for the treatment of hypertension and related diseases and conditions.
Patent NZ-628796-A (NZ)
Title: Pure erlotinib
Inventor: GORE VINAYAK GOVIND
IPC: C07D239/94
Filed: 2011-07-22
Abstract: Disclosed is a process for the preparation of erlotinib hydrochloride form A, comprising crystallisation of erlotinib hydrochloride from a solvent, wherein the solvent is a straight chain, branched or cyclic C5 to C20 alcohol (such as amyl alcohol, 1-pentanol, cyclopentanol, 1-hexanol, cyclohexanol, 1-heptanol, 1-octanol, or a mixture thereof), and wherein the erlotinib hydrochloride form A exhibits an X-ray powder diffraction (XRPD) pattern comprising at least the characteristic peaks 5.6, 9.8, 18.9, 22.7 and 23.5 ± 0.2 degrees 2θ. Also disclosed is a pharmaceutical composition comprising erlotinib hydrochloride form A when prepared by a process as defined above.
Patent NZ-702986-A (NZ)
Title: Trigger sprayer comprising a nozzle toggle switch extending through an opening in the shroud
Inventor: HOPPER SARAH
IPC: B05B11/00
Filed: 2013-07-11
Abstract: According to one aspect of the present invention, there is provided a trigger actuated pump sprayer comprising a pump body, a trigger lever, a shroud and a nozzle, wherein the trigger actuated pump sprayer further comprises a toggle switch adaptor engaging the nozzle and having an operable portion within an opening in the shroud. In this way, the operable portion of the toggle switch adapter can be guided, controlled, regulated or otherwise manipulated within or around or otherwise because of the opening in the shroud, to remotely operate at least the nozzle of the trigger actuated pump sprayer. Thus, the trigger actuated pump sprayer prevents the operator from coming into contact with the liquid being dispensed, both during spraying and when adjusting the nozzle of the sprayer.
Patent NZ-704955-A (NZ)
Title: Composition for controlling plant disease and application therefor
Inventor: MATSUZAKI YUICHI
IPC: C07D231/14
Filed: 2013-06-18
Abstract: This composition for controlling plant disease contains a compound represented by formula (I) (in the formula, R1 represents a hydrogen atom or a methyl group and R2 represents a methyl group, a difluoromethyl group, or a trifluoromethyl group) and a compound represented by formula (A) and exhibits a superior controlling effect with respect to plant disease.
Patent NZ-705917-A (NZ)
Title: Nootropic compositions for improving memory performance
Inventor: COHEN DANIEL
IPC: A61P43/00
Filed: 2013-09-04
Abstract: The invention relates to compositions comprising baclofen and acamprosate, or salt(s), or sustained release formulation(s) thereof and their use in methods for improving memory and/or memory related performances in a healthy subject who has no known clinical signs of a disease. Such improvement may be particularly desirable in healthy people having to face to high performance requirements, willing to improve, or maintain, their performances and their cognitive wellness. Such people being, for example, people punctually or chronically in need for a raising of their memory, learning, or alertness performances as students, caregivers, pilot line or, more generally, people having to face to mental fatigue, lack of sleep, mental daily stress, occupational stress, or having to deal with multi tasks activities.
Patent NZ-707145-A (NZ)
Title: Low water drying type joint compound
Inventor: ROSENTHAL GUY
IPC: C04B111/40
Filed: 2013-09-19
Abstract: A drying type joint compound composition is provided in which a significant portion of the water has been removed for reducing shipping costs. At the jobsite, the user adds water as needed to obtain the desired consistency or viscosity. The composition including: at least one binder, a filler and water, the water having a weight percentage in the range of 12-18% of the total weight of the composition, and upon formulation, approximately 75-95% of the composition passing a No. 4 screen.
Patent NZ-713047-A (NZ)
Title: Aqueous emulsion solution, coloring agent composition containing said aqueous solution, aqueous inkjet ink, and method for producing aqueous emulsion solution
Inventor: SHIMANAKA HIROYUKI
IPC: C09D17/00
Filed: 2014-04-17
Abstract: An aqueous emulsion solution is provided that can be used as a binder for forming a coating film suitable for an inkjet printing system. The present invention is an aqueous emulsion solution containing a polymer I and a polymer II mixed together therein, wherein the polymer I is an A-B block copolymer formed from 90 mass% or more of a methacrylate-based monomer, the A-B block copolymer neutralized with an alkali, a polymer block A is substantially water-insoluble and has a number average molecular weight of 1000 to 10000 and a polydispersity index of 1.5 or less, a polymer block B is synthesized using a monomer containing at least a methacrylic acid and has an acid value of 30 to 250 mgKOH/g, the A-B block copolymer has a number average molecular weight of 5000 to 20000, a content of the polymer block A of 5 to 60 % in the A-B block copolymer, and a polydispersity index as a whole of 1.6 or less, the polymer II is a polymer obtained by polymerizing a hydrophobic addition polymerizable monomer and having a glass transition temperature of 70C or lower, and further the mass ratio of the polymer I and the polymer II is 5 to 80:95 to 20.
Patent NZ-714326-A (NZ)
Title: A method of starting the locomotive cooling fan motor
Inventor: ZHIWEI CAI
IPC: H02P1/26
Filed: 2015-10-08
Abstract: The invention discloses a control method of starting the locomotive cooling fan motor, which is characterized in that, the output frequency target value of inverter is set to the lower value F1, the inverter output frequency is controlled based on the lower loading rate Rp1; when the inverter output frequency reaches F1, it can be maintained till T1. From the time of motor starting to T1, The smaller value output from output current limit and intermediate DC voltage limit (double closed-loop control) is multiplied by the degree of modulation to obtain the new degree of modulation ML. Then ML is applied to control the output voltage of the inverter, to make the output voltage limit fall within the given Max. starting current range and the intermediate DC voltage limit within the DC voltage limit range. At T1 time, if the output frequency target value of the inverter is set as the higher value F2, the inverter output frequency is controlled based on the higher loading rate Rp2, then F2 can be reached at T2. Therefore, the invention can achieve steady starting of fan motor at any initial speed and in any rotation direction, and can prevent over-voltage of the intermediate voltage of the inverter.
Patent NZ-732809-A (NZ)
Title: Antenna for identification tag and identification tag with antenna
Inventor: EADIE BRIAN
IPC: H01Q9/26
Filed: 2016-01-12
Abstract: An ultra-high frequency identification tag for attachment to an animal, said identification tag comprising: a body; an integrated circuit; an ultra-high frequency antenna device electrically connected to said integrated circuit; wherein the antenna device comprises: a meander line antenna; and a substrate; wherein said antenna device is operable to use the body of the animal to which it is attached as part of the tuning circuit of said antenna device such that said antenna device is operable to use the body of the animal as a ground plane; and wherein said antenna device is purposely detuned such that it is only tuned to a desired frequency when the tag is attached to the animal; and wherein said meander line antenna is a three-dimensional meander line antenna comprising two layers; and wherein one or more of: the dimensions of the meander line antenna, spacing between elements and layers of the meander line antenna, the number of turns of the meander line antenna; and the substrate thickness, is tuned to impedance match the antenna device to the integrated circuit to which it is to be attached, and such that no further external impedance matching components are required.
Patent NZ-735761-A (NZ)
Title: Pyrazole compounds and method for making and using the compounds
Inventor: SINGH RAJINDER
IPC: A61K31/4178
Filed: 2016-04-22
Abstract: Disclosed embodiments of the formula below concern novel interleukin receptor associated kinases (IRAK) inhibitors and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent an IRAK-associated disease or condition.