baber/WOPTO huggingface dataset:
Patent EP-3737758-A1 (EP)
Inventor: PEDERSEN LYKKE
IPC: C12N15/113
Filed: 2019-01-08
Abstract: The present invention relates to antisense oligonucleotides that are capable of modulating expression of PIAS4 in a target cell. The antisense oligonucleotides hybridize to PIAS4 pre- mRNA. The present invention further relates to conjugates of the oligonucleotide and pharmaceutical compositions and methods for treatment of cancers such as pancreatic cancer, breast cancer and liver fibrosis using the antisense oligonucleotide.
Patent EP-3746452-A1 (EP)
Inventor: ZHANG LIANHAO
IPC: C07H1/00
Filed: 2019-01-30
Abstract: Methods for stereoselective synthesis and manufacturing of 2'-deoxynucleosides, such as 2'-ribonucleosides, are disclosed. In some embodiments, the 2'-deoxynucleoside is a β-anomer of 2'-deoxynucleoside having a 3' a hydroxyl, 4' β hydroxymethyl configuration. Nonlimiting examples of compounds prepared by the disclosed methods include 4'-thio-2'-deoxycytidine (T-dCyd) and 5-aza-4'-thio-2'-deoxycytidine (5-aza-T-dCyd; aza-T-dCyd; aza-T-dC).
Patent EP-3749909-A1 (EP)
Inventor: GOLAN AMOS
IPC: F41A17/46
Filed: 2019-02-17
Abstract: An assembly (10) includes a forward unit (12) including a mounting portion (16) for mounting thereon a firearm, the forward unit (12) defining a projectile shooting axis (20), and a rearward unit (14) coupled to the forward unit (12). The rearward unit (14) includes a retractable buttstock (24) that has a retracted position and an extended position. In the extended position the rearward unit (14) is pivotable with respect to the forward unit (12) about a pivot axis (26) which is tilted relative to the projectile shooting axis (20).
Patent EP-3790695-A1 (EP)
Title: Bohrwerkzeug
Inventor: SONNTAG STEFAN
IPC: B25D17/22
Filed: 2019-04-25
Abstract: Die Erfindung betrifft ein Bohrwerkzeug, insbesondere Gesteinsbohrer, das sich entlang einer Längsachse (12) erstreckt, umfassend einen Bohrkopf (24), ein Einsteckende (16), einen Grundkörper (32), ein Hülsenelement (34), einen Transportbereich (22), der zwischen dem Bohrkopf (24) und dem Einsteckende (16) angeordnet ist, und zumindest einen Transportkanal (36), der sich entlang des Transportbereichs (22) erstreckt, wobei der Transportkanal (36) radial zwischen dem Hülsenelement (34) und dem Grundkörper (32) angeordnet ist. Es wird vorgeschlagen, dass das Hülsenelement (34) drehbar auf dem Grundkörper (32) gelagert ist.
Patent EP-3788003-A1 (EP)
Inventor: BURCHER BENJAMIN
IPC: C01B3/06
Filed: 2019-04-30
Abstract: The present invention relates to a process for producing and for regenerating siloxane hydrogen carrier compounds.
Patent EP-3803422-A1 (EP)
Inventor: AMTHOR THOMAS ERIK
IPC: G01R33/54
Filed: 2019-05-27
Abstract: It is an object of the invention to increase the predictability of the MRI exam for the patients. This object is achieved by a method for classifying sound of a magnetic resonance imaging sequence into a sound category, wherein the magnetic resonance sequence comprises a one or more sound blocks, wherein individual sound blocks have signal characteristics and wherein sound blocks having similar characteristics are to be classified into the same sound category, the method comprising the steps of: - receiving information about one or more gradient waveforms to be used in the magnetic resonance imaging sequence and; - using a classification algorithm to map the waveform information to a sound category and; - allocating a visual to the sound category.
Patent EP-3841490-A1 (EP)
Inventor: SMITH DANIEL PAUL
IPC: G16C20/70
Filed: 2019-06-17
Abstract: A system for discovering biological knowledge patterns of interest is described. The system comprises: a receive module configured to receive information defining a base pattern and a generalised base pattern, the base pattern comprising one or more entity nodes each representing a biological entity and one or more biological relationships indicated between the nodes, the generalised base pattern being related to the base pattern by virtue of replacing at least one entity node representing a respective biological entity by an associated set node representing a set of biological entities that includes the respective biological entity; a query module configured to generate a first query portion that, in combination with the generalised base pattern, defines a first query that retrieves a first set of results including the base pattern; and a control module configured to cause the query module to generate a second query portion that, in combination with the first query, defines a second query that retrieves a second set of results including the base pattern.
Patent EP-3801951-A1 (EP)
Title: Procédé et système de fabrication additive
Inventor: BARUA ANANDA
IPC: B22F3/00
Filed: 2019-06-06
Abstract: L'invention concerne un article imprimé à jet de liant, comprenant une partie, présentant une section supérieure, une section inférieure et un surplomb s'étendant à partir de la section supérieure, et une structure de support formée autour de la partie, qui peut empêcher la déformation de la partie pendant le traitement thermique post-impression. La structure de support comprend un patin positionné de façon adjacente à la section inférieure, qui peut soutenir la partie, une première pluralité d'éléments de support disposés le long d'un périmètre extérieur du patin et une seconde pluralité d'éléments de support disposés sur la section supérieure de la partie imprimée. Les première et seconde pluralités d'éléments de support forment un treillis autour de la partie imprimée, de sorte que la partie imprimée soit emboîtée dans la structure de support.
Patent EP-3801726-A1 (EP)
Inventor: PALUSHI JETMIR
IPC: A61M25/00
Filed: 2019-05-22
Abstract: An apparatus (100) includes a shaft (102), an expandable dilation member (106), and a bulbous tip (120). The shaft has a first outer cross-sectional dimension. The dilation member is positioned proximal to the distal end (104) of the shaft. The dilation member is operable to transition between a non-expanded configuration and an expanded configuration. The dilation member is sized to pass through a passageway associated with drainage of a paranasal sinus or a Eustachian tube when the dilation member is in the non-expanded configuration. The bulbous tip is positioned at the distal end of the shaft. The bulbous tip is distal to the dilation member. The bulbous tip has a second outer cross-sectional dimension. The second outer cross-sectional dimension is larger than the first outer cross-sectional dimension. The bulbous tip is removably secured to the distal end of the shaft.
Patent EP-3737539-A1 (EP)
Title: Procédé de surveillance d'unités à température contrôlée dans un magasin
Inventor: TIWARI DURGESH
IPC: G06K19/06
Filed: 2019-01-10
Abstract: Une variante d'un procédé de surveillance d'unités de refroidissement dans un magasin consiste à : au niveau d'un système robotique, pendant une première routine de balayage, naviguer de façon autonome vers une unité de refroidissement dans le magasin, enregistrer une image couleur de l'unité de refroidissement, et balayer un ensemble de températures à l'intérieur de l'unité de refroidissement ; identifier un ensemble de produits stockés dans l'unité de refroidissement sur la base de caractéristiques détectées dans l'image couleur ; mapper l'ensemble de températures à l'ensemble de produits à un premier instant pendant la première routine de balayage sur la base de positions de produits dans l'ensemble de produits identifiés dans l'image couleur ; et générer un enregistrement de températures de l'ensemble de produits stockés dans l'unité de refroidissement au premier instant.
Patent EP-3637090-A1 (EP)
Inventor: NA SUMIN
IPC: G01N33/00
Filed: 2019-01-16
Abstract: The present invention relates to a method for quantitatively analyzing hydrogen gas generated by the decomposition of Si-OH (silanol) in porous silica as a support of a metallocene catalyst. According to the method of present invention, the content of hydrogen present in trace amounts in silica can be measured by using an inert gas fusion-infrared absorption (IGFIA) method under specific pressure and temperature conditions.
Patent EP-3826597-A1 (EP)
Inventor: LINDNER TORSTEN
IPC: C09J153/00
Filed: 2019-07-24
Abstract: Described herein is an absorbent article having an absorbent core. The absorbent core includes a superabsorbent polymer material and a superabsorbent polymer immobilizing material. The superabsorbent polymer immobilizing material includes from about 20% to about 70% of a first polymer and from about 30% to about 80% of a second polymer. The superabsorbent polymer immobilizing material has a Shear Viscosity at 10 (1/s) at 230 °C of from about 300 mPa·s to about 10,000 mPa·s.
Patent EP-3752602-A1 (EP)
Inventor: ZUNIGA-PFLUCKER JUAN CARLOS
IPC: C07K14/705
Filed: 2019-02-14
Abstract: A method of generating cells of the T cell lineage is provided comprising (a) culturing a sample comprising stem cells or progenitor cells with a Notch ligand conjugated to a suspension support and (b) isolating cells of the T cell lineage. In one embodiment, the cells of the T-cell lineage are progenitor T cells or mature T cells. Compositions, kits and uses thereof are also provided.
Patent EP-3831159-A1 (EP)
Inventor: CHEN TEMING
IPC: H04W48/18
Filed: 2019-08-08
Abstract: This document describes techniques and apparatuses for handling Public Land Mobile Network (PLMN) selection while user equipment (110) is in an inactive mode at a radio resource control layer. In aspects, the UE performs (502) a cell-selection procedure that selects a first cell that serves a first Public Land Mobile Network (PLMN). The UE establishes a radio connection (504) to the first PLMN. The UE transitions (506) from a connected mode at a radio resource control layer to an inactive mode at a radio resource control layer. After a period of time, the UE performs a cell-reselection procedure (508) that selects a second cell that serves a second PLMN. The UE determines (510) if the second PLMN is an equivalent PLMN to the first PLMN. If the second PLMN is an equivalent PLMN to the first PLMN, the UE sends (512) an indication to a lower layer that triggers an action.
Patent EP-3723777-A1 (EP)
Title: Compositions comprising bacterial strains
Inventor: YUILLE SAMANTHA
IPC: A61K35/741
Filed: 2019-06-25
Abstract: The invention provides compositions comprising bacterial strains for use in therapy.
Patent EP-3834189-A1 (EP)
Title: Verfahren und steuervorrichtung zum warnen eines fahrers eines kraftfahrzeugs sowie kraftfahrzeug mit einer derartigen steuervorrichtung
Inventor: WENDLAND HANNES
IPC: G06K9/00
Filed: 2019-07-30
Abstract: Die Erfindung betrifft ein Verfahren zum Warnen eines Fahrers eines Kraftfahrzeugs (1) sowie eine Steuervorrichtung (6) für ein Kraftfahrzeug (1). Das Verfahren umfasst folgende Schritte: Empfangen von Positionsdaten eines ersten Objekts (10) mittels des Kraftfahrzeugs (1) von einer fahrzeugexternen Kommunikationseinrichtung (7), Erfassen einer Fahrzeugumgebung mittels einer Erfassungseinrichtung (5) des Kraftfahrzeugs (1), und Erfassen einer Eigenposition des Kraftfahrzeugs (1). Zudem erfolgt ein Überprüfen, ob von der Erfassungseinrichtung (5) in einem anhand der empfangenen Positionsdaten und der Eigenposition bestimmten Sichtbereich (13) zwischen dem Kraftfahrzeug (1) und dem ersten Objekt (10) ein das erste Objekt (10) verdeckendes zweites Objekt (4) erfasst wird, und ob sich durch das erste Objekt (10) eine potentiell kritische Situation für das Kraftfahrzeug (1) ergibt. Falls erkannt wird, dass das erste Objekt (10) verdeckt ist, und sich durch das erste Objekt (10) die potentielle kritische Situation für das Kraftfahrzeug (1) ergibt, erfolgt ein Einleiten einer vorgegebenen Warnkaskade.
Patent EP-3780208-A1 (EP)
Inventor: NARIYAMA HONAMI
IPC: H01M8/18
Filed: 2019-02-13
Abstract: A flow battery includes a first liquid containing a first electrode med iator, a first electrode, a first active material, and a first circulator that circulates the first liquid between the first electrode and the first active material. The first electrode mediator includes at least one benzene derivative that contains at least a pair of alkoxy groups located at para positions relative to each other.
Patent EP-3840859-A1 (EP)
Inventor: SENG GUIDO
IPC: B01D53/86
Filed: 2019-08-16
Abstract: Presented is a process for the regeneration of a deactivated nitrogen oxide decomposition catalyst of a selective catalytic reduction system that is a component of a flue gas treating system that is one of parallel flue gas treating systems. The selective catalytic reduction system is isolated to provide a closed system in which a regeneration gas is circulated to regenerate the deactivated nitrogen oxide decomposition catalyst. Denitrified flue gas from a parallel flue gas treating system is introduced and used within the closed system as regeneration gas.
Patent EP-3761675-A1 (EP)
Inventor: KOSAREV SERGEY ALEXANDROVICH
IPC: H04W4/00
Filed: 2019-02-21
Abstract: The invention relates to wireless communication. The technical result of the invention is to increase network capacity, prevent collisions between data packets being transmitted within a network and increase the range of coverage for reading sensor readings remotely. For this purpose, base stations (BS) having an identical number of channels for receiving narrowband modulation (UNB) are divided into groups, wherein data transmission channels of all the base stations have identical time and frequency characteristics. All subscribers split into groups are periodically sent messages with subscriber group numbers by all the base stations. When a group number of a corresponding subscriber coincides with a group number in a message received by said subscriber, all the subscribers of said group send response messages to the base stations using UNB, wherein response messages are sent sequentially from all subgroups of subscribers of said group, and subscribers of a subgroup send response messages on different frequencies. The base stations receive the response messages on all frequencies corresponding to subscribers, decode said messages and generate a database of response messages, which can be used for generating subsequent messages with corresponding subscriber group numbers.
Patent EP-3768098-A1 (EP)
Title: Glycosides de stéviol présentant des solubilités, des profils de goût et des effets aromatisants améliorés
Inventor: JACKSON MEL CLINTON
IPC: A23L33/125
Filed: 2019-03-22
Abstract: La présente invention concerne une composition de glycoside de stéviol qui comprend un ou plusieurs glycosides de stéviol, un ou plusieurs sels, et un ou plusieurs édulcorants à base de glycoside non stéviol. La composition de glycoside de stéviol présente une solubilité et des profils sensoriels améliorés et peut être utilisée comme édulcorant ou comme agent aromatisant.
Patent EP-3773626-A1 (EP)
Inventor: YEE CASSIAN
IPC: A61K35/17
Filed: 2019-03-28
Abstract: The present disclosure provides methods for re-programming effector T cells to a central memory phenotype comprising culturing the effector T cells with a histone deacetylase inhibitor (HDACi) and IL-21. Further provided are methods of treating cancer comprising administering the central memory T cells.
Patent EP-3779849-A1 (EP)
Title: Device and method for monitoring activity in fish
Inventor: CABRUJA CASAS ENRIC
IPC: A01K61/10
Filed: 2019-03-27
Abstract: The invention relates to a device placed on the operculum to monitor the metabolic state and well-being of fish through joint, simultaneous measurements of breathing frequency and physical activity via a plurality of accelerations that are coplanar (x and y axes) and normal to the operculum (z axis). The substrate is flexible and is covered with an water-resistant coating, which contains an electronic circuit with an acceleration sensor (208), a control unit (202), a microcontroller (206) configured to execute at least one activity-monitoring routine, a memory (210) and a battery (204). Data are collected via an external unit (201) which can optionally process them in a complete or partial manner. This type of measurement can be processed jointly with another type of measurement, obtained from other sensors of environmental parameters.
Patent EP-3776125-A1 (EP)
Title: System and method for estimating uncertainty of the decisions made by a supervised machine learner
Inventor: KOLOURI SOHEIL
IPC: G06N3/08
Filed: 2019-01-30
Abstract: Described is a system for controlling autonomous platform. Based on an input image, the system generates a motor control command decision for the autonomous platform. A probability of the input image belonging to a set of training images is determined, and a reliability measure for the motor control command decision is generated using the determined probability. An exploratory action is performed when the reliability measure is above a predetermined threshold. Otherwise, an exploitation action corresponding with the motor control command decision is performed when the reliability measure is below a predetermined threshold.
Patent EP-3844734-A1 (EP)
Inventor: MAIR GAVIN
IPC: G09B1/06
Filed: 2019-08-29
Abstract: An education tool (1) comprises a sheet (2) with a plurality of small pockets (3) formed across it's front face, and a rear pocket (4) formed across it's rear face, the sheet (2) and the pockets (3, 4) formed from a transparent material; the large rear pocket (4) configured so that an answer card (7) can be inserted therein to show a series of answers frontwards, and a picture rearwards; the small pockets holding in use a plurality of question cards (8), their inner faces showing part of a larger picture, their outer faces showing a question; the question cards (8) and answer card (7) configured so that when all the question cards (8) are inserted in the correct locations, the part pictures on their rear faces will mosaic to show substantially the same picture as on the rear of the answer card (7).
Patent EP-3810149-A1 (EP)
Inventor: KRISHNAN SUMA
IPC: A61K35/76
Filed: 2019-04-26
Abstract: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding one or more cosmetic proteins (e.g., one or more human collagen proteins); viruses comprising the recombinant nucleic acids; compositions (e.g., cosmetic formulations) comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
Patent EP-3652566-A1 (EP)
Inventor: MARC ETIENNE
IPC: G01V1/38
Filed: 2019-10-02
Abstract: Systems and methods for delivering seismic data acquisition units to an ocean bottom are provided. A system includes an underwater vehicle including with sensors to determine environmental information. A control unit obtains, based on the environmental information and a policy, an indication to perform a fly-by deployment. The control unit sets an angle of a ramp with respect to a base of the underwater vehicle. The control unit identifies a launch event for a seismic data acquisition unit of a plurality of seismic data acquisition units stored in the underwater vehicle, and deploys the seismic data acquisition unit from the ramp towards the ocean bottom based on the identification of the launch event and the environmental information.
Patent EP-3915234-A1 (EP)
Inventor: CHEN HUAIMO
IPC: H04L12/755
Filed: 2019-10-21
Abstract: A method performed by a network node (N1) for handling Interior Gateway Protocol (IGP) flooding topology inconsistency. The method obtains a new flooding topology. The new flooding topology can be obtained by computing or receiving the new flooding topology. The method sets a flooding topology flag field (FT field) in a data packet to indicate whether the link between N1 and a second node (N2) is on the new flooding topology. The method transmits the data packet containing the flooding topology flag field to N2.
Patent EP-3794815-A1 (EP)
Inventor: SUK JIHE
IPC: G09F9/30
Filed: 2019-01-30
Abstract: A flexible TV is disclosed. The flexible TV includes a housing, a user interface configured to receive at least one command, a flexible display positioned in the housing, and a controller configured to control a door and a motor. In particular, the controller determines a range of the flexible display exposed to an outside of the housing by controlling at least one of the door or the motor according to a type of the command.
Patent EP-3902855-A1 (EP)
Inventor: BRANDAU SVEN
IPC: C08F236/14
Filed: 2019-11-25
Abstract: What are provided are pulverulent mixtures based on specific nitrile rubbers and at least one separating agent, and also a process for producing vulcanizable mixtures and vulcanizates made from these pulverulent mixtures, and the resultant vulcanizates and their use, especially in tyre treads, where an improvement in wet skid resistance, dry grip and rolling resistance delivers is observed with simultaneously good mixing characteristics.
Patent EP-3890688-A1 (EP)
Inventor: VIGNA IVAN
IPC: A61K8/92
Filed: 2019-10-22
Abstract: La présente invention concerne le procédé de modification de l'odeur d'une huile ozonisée comprenant l'association de l'huile ozonisée avec de l'huile essentielle de citronnelle et/ou de camomille romaine, et les compositions, également pharmaceutiques, les contenant.
Patent EP-3801574-A1 (EP)
Inventor: COOPER MATTHEW
IPC: C12N5/0783
Filed: 2019-05-31
Abstract: Disclosed herein are methods of genome-editing and transduction of T cells and methods of immunotherapy in using them. In particular, the disclosure relates to engineered chimeric antigen receptor (CAR)-bearing T cells and methods of using the same for the treatment of cancer.
Patent EP-3886761-A1 (EP)
Inventor: NAE Nir
IPC: A61F2/07
Filed: 2019-11-27
Abstract: Systems and methods for the manufacture of an hourglass shaped stent-graft assembly comprising an hourglass shaped stent, graft layers, and an assembly mandrel having an hourglass shaped mandrel portion. Hourglass shaped stent may have superelastic and self-expanding properties. Hourglass shaped stent may be encapsulated using hourglass shaped mandrel assembly coupled to a dilation mandrel used for depositing graft layers upon hourglass shaped mandrel assembly. Hourglass shaped mandrel assembly may have removably coupled conical portions. The stent-graft assembly may be compressed and heated to form a monolithic layer of biocompatible material. Encapsulated hourglass shaped stents may be used to treat subjects suffering from heart failure by implanting the encapsulated stent securely in the atrial septum to allow blood flow from the left atrium to the right atrium when blood pressure in the left atrium exceeds that on the right atrium. The encapsulated stents may also be used to treat pulmonary hypertension.
Patent EP-3831410-A1 (EP)
Inventor: HU WEIGUO
IPC: A61K45/06
Filed: 2019-04-10
Abstract: The present invention discloses a pharmaceutical composition for treating B-cell lymphoma, including a PI3K/AKT signaling pathway inhibitor and a chemotherapeutic drug, and further including a monoclonal antibody targeting CD20, such as rituximab. The pharmaceutical composition provided by the present invention is particularly suitable for the treatment of relapsed/refractory B-cell lymphoma. Given the critical role of cancer stem cells (CSCs) in the process of metastasis and drug resistance, the present invention proposes a new pro-differentiation therapy (PDT) strategy to cope with CSCs, i.e. to determine the decisive signaling pathway that maintains stem cell sternness and then promotes CSC differentiation by interfering with the pathway. Differentiated cells are eventually sensitive to conventional therapies, such as chemotherapy. In this situation, the PI3K/AKT signaling pathway inhibitor in combination with an R-CHOP regimen has a good effect on the treatment of drug-resistant diffuse large B-Cell lymphoma (DLBCL).