baber/WOPTO huggingface dataset:
Patent AP-1486-A (AP)
Title: Indazole Compounds And Pharmaceutical Compositions For Inhibiting Protein Kinases, And Methods For Their Use.
Inventor: KANIA ROBERT STEVEN
IPC: C07D401/04
Filed: 2000-06-30
Granted: 2005-11-01
Abstract: Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
Patent DO-P2006000166-A (DO)
Title: Complejos metálicos con contenido de perfluroalquilo, procedimientos para su preparación, así como su uso
Inventor: MISSELWITZ BERND
Filed: 2006-07-13
Abstract: La invencion se refiere a los objetos caracterizados en las reivindicaciones, a saber, complejos metalicos con contenido de perfluoroalquilo con grupo N-alquilo de la formula general I, a procedimientos para su preparacion y a su use en el diagnostico por RMN y rayos X, en el radiodiagnostico y 1a radioterapia, asi como en la linfografia MRT.
Patent DO-P2014000177-A (DO)
Title: Nuevos derivados de morofolinilo útiles como inhibidores de mogat-2
Inventor: GONZALEZ-GARCIA MARIA ROSARIO
IPC: A61K31/5375
Filed: 2014-07-30
Abstract: La presente invención se refiere a compuestos de Fórmula I o una sal farmacéutica de los mismos, métodos para tratar hipertrigliceridemia usando los compuestos; y a un proceso para preparar los compuestos.
Patent DO-P2022000232-A (DO)
Title: Compuestos de 2,4-dioxopirimidina inhibidores de cd73
Inventor: SCOTT D SCHROEDER
IPC: C07D487/04
Filed: 2022-10-26
Abstract: La presente divulgación proporciona compuestos de pirimidina diona y composiciones farmacéuticas de los mismos para tratar el cáncer, incluidos los tumores sólidos. Los compuestos se pueden usar solos o en combinación con otros agentes anticancerígenos.
Patent EC-SP11010987-A (EC)
Title: Aparato para la perforación y la recoleción de la sección ocular de pescados
Inventor: MIKAJIRI AKIHIRO
IPC: E21B31/107
Filed: 2011-04-15
Abstract: El problema para ser resuelto) Proveer un aparato para eficazmente y precisamente perforar y recolectar de una manera continua y automática la sección ocular de un pez como un bonito o un atún, que contiene grandes cantidades de ácidos grasos. (Solución) El aparato comprende una mesa de apoyo para la parte de la cabeza 2 y una mesa de apoyo para la parte corporal 3 que pueden ser abiertas y cerradas. La mesa de apoyo para la parte de la cabeza tiene un hueco de descarga para la sección ocular 4 y se provee con un medio de agarre para la parte de la cabeza 9 localizado a los dos lados de la mesa de apoyo para la parte de la cabeza 2 para posicionar una sección ocular B del pez A sobre el hueco de descarga para la sección ocular 4. El aparato además comprende un cuerpo de cuchilla para la perforación de la sección ocular 7 localizado sobre el hueco de descarga de la sección ocular 4 de una manera que se pueda mover para arriba y para abajo. La sección ocular B del pez A es perforado por el cuerpo de cuchilla de perforación 7, y el ojo perforado B es recolectado a través de una manguera de succión 25 conectado a y comunicándose con una superficie inferior del hueco de descarga de la sección ocular 4. Después del tratamiento de perforación de la sección ocular B, la mesa de apoyo para la parte de la cabeza 2 y la mesa de apoyo para la parte corporal 3 se abren al mismo tiempo para descargar el pez A hacia abajo.
Patent EE-200100172-A (EE)
Inventor: SENN-BILFINGER JOERG
IPC: C07D471/14
Filed: 1999-09-17
Abstract: The compound (7R,8R,9R)-2,3-Dimethyl-8-hydroxy-7-(2-methoxyethoxy)-9-phenyl-7,8,9,10-tetrahydro-imidazo-[1,2-h] [1,7] naphthyridine inhibits the secretion of gastric acid.
Patent EE-200200262-A (EE)
Inventor: ODEGAARD MARIT ROD
IPC: C05G3/00
Filed: 1999-11-23
Abstract: Chemical composition to be used as additive for fertiliser composition, comprising 35 - 60 % by weight of magnesium sulphate, 5 - 35 % by weight of calcium sulphate, 10 - 35 % by weight of a mixture containing magnesium carbonate and calcium carbonate up to 5 % by weight of water, either free or bound as crystal water, and the balance magnesium oxide.
Patent GB-189707333-A (GB)
Title: Improvements in Gas, Petroleum, or like Motors.
Inventor: BRUN ALBERT EDOUARD LE
Filed: 1897-03-20
Granted: 1897-04-24
Abstract: 7333. Le Brun, A. E. March 20. Drawings to Specification. Flywheels.-The flywheel of a gas engine forms the female portion of a friction clutch for conveying motion to a shaft coaxial with the crank shaft.
Patent GB-189710249-A (GB)
Title: Improvements in or connected with Apparatus for the Production and Consumption of Acetylene Gas.
Inventor: THOMPSON WILLIAM PHILLIPS
Filed: 1897-04-24
Granted: 1897-06-12
Abstract: 10,249. Thompson, W. P., [Deutsche Acetylengas-Gesellschaft mit Beschrõnkter Haftung]. April 24. Acetylene and like lamps.-Mounted upon a rod A, Fig. 1, vertically adjustable in a stand B, is a casing C for receiving a carbide holder, provided with a tightly-fitting door which is closed by a bar c engaging a hook c<1>. The casing is divided by a plate d which shuts off the water chamber and serves to keep the gas cool. Water is supplied to the - carbide by a pipe F which ends in a valve consisting of a perforated diaphragm beneath which are flaps of leather. When the gas pressure exceeds that of the head of water the valve cuts off further supply of water and generation of gas is suspended. The gas pipe E leads directly to the burners without passing through the water, in order to avoid condensation of moisture. In the foot lamp shown in Fig. 2, the gas pipe passes through the water chamber D, but is protected from contact with the water by an outer pipe. This Figure also shows an apparatus for carrying off the gas remaining in the lamps when they are extinguished. This consists of a pipe J leading to the exterior of the building or to a holder, and provided with branches K which are fitted with weighted self-closing valves k for connection by flexible tubing with the lamps to be exhausted. In the pipe J is a safety-valve, the leg L of which contains water for determining the pressure at which the gas can pass. When the gas pressure is sufficient, the water is lifted into the bulb L', Fig. 4, and the gas escapes. The combination of a generator of the kind shown in Fig. 1 with the foot or other part of a lamp post is also described.
Patent GB-189712581-A (GB)
Title: Improvements in Cycle Back Fork Ends for use in conjunction with Chain Adjustments.
Inventor: BRIGGS FREDERICK WILLIAM
Filed: 1897-05-21
Granted: 1897-12-18
Abstract: 12,581. Briggs, F. W. May 21. Forks; frames; chains, adjusting tension of.- Relates to a construction of back-fork end for use in connection with chain-adjusting devices. Fig 5 shows an underside plan of a bicycle. The backfork ends a are made of D-section, and the ends a<2> are closed by plates a<3> provided with lugs a<5> through which pass the adj usting-bolts b, b<2>. The bolts b lie in longitudinal slots a<6> formed in the inner flat sides of the fork ends. The ends d<1> of the wheel spindle pass through the eyes b<2> of the adjusting-bolts and through the slots a<6>, securing or lock nuts f being screwed thereon as shown. Slots a<10> are formed in the fork ends to enable the nuts f to be tightened against the flat faces a<9>. The eyes of the adjusting-bolts are preferably screw-threaded.
Patent GB-189721477-A (GB)
Title: Improvements in Brakes for Cycles.
Inventor: BAUCKHAM WILLIAM
Filed: 1897-09-18
Granted: 1898-08-20
Abstract: 21,477. Bauckham, W. Sept. 18. Brakes for bicycles &c. A cord h, secured at one end h<1> to a bracket j<1> fixed to the tube c of the machine, passes round a grooved wheel i and under guide-pulleys such as k, l<1> to the handle-bar lever p. The grooved wheel i is mounted on the pedal axle, and may be formed integral with or attached to the chain-wheel e, or it may be fixed to the driving-wheel or on an independent axle. The cord h passes through a forked end on the lever p and the end of the cord is attached to a screw n<1> which takes into a lug o formed upon the brake lever, thus making the cord adjustable. By operating the lever p the brake is applied.
Patent GB-189724103-A (GB)
Inventor: HULL CHARLES CLIFFORD
Filed: 1897-10-19
Granted: 1898-08-20
Abstract: 24,103. Hull, C. C. Oct. 19. Bottles etc.; unwiring bottles.-Relates to a tool for retaining broken corks in bottles &c., to prevent them from obstructing the outflow of the contents, and is applicable also as an ice-breaker, or for unwiring champagne bottles &c. The tool consists of a wire A pointed at one end and bent to form a hook C for the finger at the other end. The pointed end is also provided with a stop disc B. When used for retaining broken corks, the pointed end is inserted in the cork, and the tool is then held with one finger by the hook C while pouring out the contents. In a modification, the hooked end is replaced by a head furnished with a spring adapted to grip the neck of the vessel.
Patent GB-189724138-A (GB)
Title: Improvements in Photographic Dry-plate Holders.
Inventor: SCHAUB JACOB
Filed: 1897-10-19
Granted: 1898-08-20
Abstract: 24,138. Schaub, J. Oct. 19. Dark slides.-Relates to a dark slide designed to facilitate the insertion and removal of plates. In the double-dark slide, shown in Fig. 2, the sections 7 of the bottom cross-bar are hinged to the fixed middle section 4, by a strip of flexible material 8 or otherwise. On opening this section 7, the dryplate x can easily be inserted or removed. The shutters 5 fit into grooves in the sections 7 when they are closed. The sections 4 and 7 are rabbeted at 10, so as to fit firmly together. Otherwise the construction is the same as in ordinary dark slides.
Patent GB-189728261-A (GB)
Title: Improvements in Printing Machines.
Filed: 1897-11-30
Granted: 1898-09-24
Abstract: 28,261. Lake, H. H., [Cottrell & Sons Co., C. B.]. Nov. 30. Cylinder machines with plane printing-surfaces.- Relates to the registering-gearing by which the cylinder and bed are brought to corresponding speeds at the reversal of the movements of the bed. Fig. 1 shows in sectional elevation a perfecting-machine of which B is the bed driven in a usual way by the rack E and wheel D, and C, C<2> are the cylinders, which may be driven independently of the bed by any suitable means. On the ends of the bed are racks F<1>, F<2> which at the ends of the movements of the bed gear with segments E', E<2>, respectively, on the cylinders. The outer ends f<2> of the racks are curved upwardly, and the corresponding ends of the segments are curved inwardly, and are at these parts eccentric to the axes of the cylinders. The eccentric ends first come into gear with the curved ends f<2>, and prevent thumping action as the teeth come into gear. In a modification, the curved ends f<2> &c. are formed without teeth.
Patent GB-189729069-A (GB)
Title: Improvements in Syntonic Telegraphy.
Inventor: LODGE OLIVER JOSEPH
Filed: 1897-12-08
Granted: 1898-10-08
Abstract: 29,069. Lodge, O. J., and Muirhead, A. Dec. 8. Drawings to Specification. Switches for use in syntonic telegraph systems. The coherer circuits are varied and controlled by means of a rotating cylindrical switch so that the coherer is (1) connected to the receiving-areas ; (2) connected to the receiver signal circuits ; and (3) connected to the decohering apparatus, either mechanical or electrical.
Patent GB-189802894-A (GB)
Title: Improvements in Surgical Trusses.
Inventor: WHITE ALBERT
Filed: 1898-02-04
Granted: 1898-12-23
Abstract: 2894. White, A. Feb. 4. Trusses.-From a waist-band a, supported by adjustable shoulder straps c, are suspended by adjustable s t r a p s l, m, and n a pair of groin pads f, which are united together at the bottom and provided at the top with an adj ustable connecting- strap h. Between the pads is an opening g for the passage of the scrotum &c.
Patent GB-189803857-A (GB)
Title: Improvements in Power Transmitting Paddles for Boats and the like.
Inventor: LORD WILLIAM TURNER
Filed: 1898-02-16
Granted: 1898-12-03
Abstract: 3857. Lord, W. T. Feb. 16. Actuating pumps by water-current motors. Consists of means for giving to paddles P for propelling boats an efficient working stroke and a direct return stroke, the apparatus being capable of use as a motor if the paddles are immersed in running water. The paddles are pivoted at F to cranks D from which they are operated, and at their upper ends to links C. Slight modifications of the linkwork are described.
Patent GB-189804312-A (GB)
Title: Improvements in or relating to Motor Propulsion of Cycles.
Inventor: BUETIKOFER EDUARD
Filed: 1898-02-21
Granted: 1899-02-04
Abstract: 4312. B³tikofer, E. Feb. 21. Drawings to Specification. Hubs.-Relates to motor cycles in which the fixed axle of the wheel forms the cylinder for the motor. The hub of the wheel is provided with holes for the passage of air to the cooling-ribs of the cylinder.
Patent GB-189807709-A (GB)
Title: Improved Apparatus for Advertizing.
Inventor: NISTER ERNEST
Filed: 1898-03-31
Granted: 1899-02-18
Abstract: 7709. Nister, E., and Loefftz, T., [trading as Nister, E.], and Jones, T. J. March 31. Advertising.-Pictures or devices of the nature of an advertisement or the like are represented on two cards A, B, Figs. 1 and 2, the picture on one being different to that on the other. The cards, which are divided, as shown, into sections or sectors, are mounted on the same spindle, and one is rotated so that its sections pass alternately at the front and rear of the sections of the other card, thus exhibiting two pictures alternately. Hydraulic and electric devices for rotating the card and allowing intervals of rest are described ; but any suitable actuating-device may be used.
Patent GB-189809495-A (GB)
Title: Improved Procedure for Advertising.
Inventor: NAWROTH PAUL
Filed: 1898-04-25
Granted: 1898-07-30
Abstract: 9495. Nawroth, P. April 25. Advertising.-The portrait of a person other than the advertiser is used in connection with advertisements, which latter may be in newspapers or on cards, prospectuses, postcards, playing cards, placards, letter headings, &c. The person whose portrait is exhibited may or may not be remunerated.
Patent GB-189810149-A (GB)
Title: Improvements in Washing Machines.
Inventor: GIBBINS WILLIAM GEORGE
Filed: 1898-05-03
Granted: 1899-03-18
Abstract: 10,149. Gibbins, W. G. May 3. Washing-machines. -Relates to a machine in which the articles are squeezed at regular intervals and the expressed water removed from the machine. Fig. 3 shows a vertical section. The receptacle 1, shaped as shown, is mounted on trunnions, and is swung to and fro by means of the handle 15 ; when at rest it is held in the vertical position by means of the spring 5. The partition 6 is connected to springs which hold it vertically, so that the clothes are squeezed between it and the sides of the receptacle 1 as the latter is rocked to and fro. The outlets 9 are provided with valves 10, one or other of which is lifted by the arm 11 when the receptacle 1 is sufficiently inclined. Washing -liquid may be introduced through a hollow trunnion. Two modifications are described in which the machine is driven by power, the construction in each case being very similar to the above.
Patent GB-189810358-A (GB)
Title: Improvements in the Manufacture of Tin, Terne, and like Plates.
Inventor: JOHNSON WILLIAM BURGELAND
Filed: 1898-05-06
Granted: 1899-03-25
Abstract: 10,358. Johnson, W. B., [Rogers, W.]. May 6. Annealing; tinning and similarly coating metals.- The plates, after being hot-rolled, are annealed in a box. The plates, without previous pickling to remove the scale, are placed on a base-plate b having a flange c, and are covered by a sheet-iron envelope e, which may be made in one part with an open bottom or in two parts fitting telescopically one over the other. The outer box a is then put on, the space within the flange c and that between the two casings being packed with pulverized iron ore, sand, lime, dolomite, or other suitable ma terial. In a modified form of annealing-box, the outer casing is closed at the bottom and is open at the top, where it is covered by a removable lid, a packing of iron ore &c. being used in this case also. In either case, the annealing-box is placed in a furnace, and heated to about 2,500‹ F. for about ten hours. The sheets are allowed to become cold. They are then removed, and are afterwards washed in water for half an hour, leaving the iron in a slightly-porous condition. The sheets are then dipped into a pot of molten grease, preferably tallow, and next placed one at a time in a rack which carries from 50 to 600 plates and can be raised and lowered into a bath of the molten metal, such as tin, used to coat the plate. The plates remain for about ten minutes in this bath at a temperature of about 450‹ F. After removal, they are placed in another bath of tin &c. which is maintained at about 25‹ F. lower in temperature than the first bath. The plates are afterwards passed one at a time into the pot shown in Fig. 6. This pot, heated by a furnace q and flues n, may be charged with molten tin up to the line x, x, and above that with grease kept cool by cold-water pipes s. Or it may be charged with grease only. Each plate is pressed by the polished steel rolls t, t and copper rolls u, u, as it passes downwards and then upwards, the rolls being geared together by an idle wheel v and driven by belts as shown.
Patent GB-189814486-A (GB)
Title: Improvements in or relating to Carburettors.
Inventor: CASGRAIN HENRI EDMOND
Filed: 1898-06-30
Granted: 1898-12-23
Abstract: 14,486. Casgrain, H. E. June 30. Gas or explosivevapour engines, carburetting-apparatus for. The apparatus is described as adapted for use on an oil engine, gasoline or heavy oils may be used in it, and it is protected from heat by a non-conducting jacket A<3>. The air is drawn in through the holes D and the valve E', and is compelled to pass through a restricted passage A<6>; it lifts a disc C<1> on the spindle C of the oil valve C', and allows oil to issue through the orifices B' and mix with the air. The disc C' has vanes C<3> on its periphery which cause it to rotate rapidly and mix the oil and air as they pass. When the air current ceases, the vanes screw the valve down on to its seating ; the lift of the valve is adjusted by a screw stop F. The volume of air passing through the apparatus is controlled by a valve H.
Patent GB-189824827-A (GB)
Title: Improvements in Anti-vibration Wheels.
Inventor: SPENCER AUBREY FREDERICK
Filed: 1898-11-24
Granted: 1899-10-14
Abstract: 24,827. Spencer, A. F. Nov. 24. Wheels.-Relates to an elastic wheel for vehicles, skates, and other purposes, and is applied to a skate wheel in the section shown in Fig. 1. The rim a has a c e n t r a l inwardlydepending flange a<1>, on each side of which a rubber disc d, having a flange d<1>, is secured in position by washers e and nuts c, c<1>, screwed on to the hub b. A lock-nut may be interposed between the washer e and nut c, and in vehicle wheels the rim a acts as a ring to which the inner ends of the spokes are secured. According to the Provisional Specification, the rubber discs may be replaced by chambers filled or partially filled with air or water.
Patent GB-189901140-A (GB)
Title: Improvements in or connected with Spindle and Hub Protectors.
Inventor: HOLDEN WILLIAM HAROLD
Filed: 1899-01-17
Granted: 1899-03-04
Abstract: 1140. Holden, W. H. Jan. 17. Wheels.-Figs. 2 and 3 show the application of a protector to the axle and hub of a road vehicle, but the invention is stated to be applicable to all classes of wheeled vehicles. The bell-shaped sheath 5 has top and bottom extensions 8 and 9 respectively, which are secured to the axle 2 by the clip 12, which has side ears 13 to cover the openings 7. The hub 3 is fitted at its inner end with a collar 16 of triangular shape in cross-section, capable of revolving freely in the flared portion 4 of the sheath 5, and the face 17 acts to exclude dust &c. from the bearing.
Patent GB-189901560-A (GB)
Title: Improvements in Adjustable Fastening Devices for Driving Belts.
Inventor: MUSCIACCO AUGUSTO
Filed: 1899-01-23
Granted: 1899-04-08
Abstract: 1560. Musciacco, A. June 23, A.D. 1898, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Belt and band fastenings.-Between a pair of side-plates A are mounted rollers B and N. The ends of the belt are each led over one of the rollers N and secured to one of the rollers B by a plate H and screws G. The rollers B are provided with ratchet-wheels and spring pawls, and may be turned by a key to tighten up the belt, which is then further secured by screwing down the bar M.
Patent GB-189902289-A (GB)
Title: Improved Method of Marking Out the String Boards of Staircases, and Implement for Use in connection therewith.
Inventor: ZELTNER-DIETZ JOHANNES
Filed: 1899-02-01
Granted: 1899-04-08
Abstract: 2289. Zeltner-Dietz, J. Feb. 1. Tools for setting-out work; bevels.-Relates to a tool for marking the stringboards of staircases. The tool consists of two bars A, C of L section hinged together and connected by a bar B which may be made to slide on the bar A or the bar C. All the bars are graduated and slotted for setscrews fixing the bar B and marker d'. There are also fixed markers d, f and sliding markers g, h. In using the tool, the bar B is fixed so that its distance from the pivot x is equal to the average width of the tread, and the length marked on the bar B by the marker d' is equal to the height of the riser. The bar A then gives the inclination of the stringboard I, Fig. 2, when fixed. The horizontal lines 1, 2, 3, &c. are then drawn at a distance apart equal to the height of the riser, and the widths a, b, c, d, e, f, of the treads at the stringboard are taken from the builder's plan of the staircase and marked by the markers g, h.
Patent GB-189904626-A (GB)
Title: Curtain and Portiere Rods or Holders in which the Arms Carrying the Curtains Swing in a Radial Direction.
Inventor: RANDIG ADOLPH OTTO
Filed: 1899-03-02
Granted: 1899-04-15
Abstract: 4626. Randig, A. O. March 2. Curtains, drawing and suspending.-Two rods a, b, one shorter than the other, are carried on pivots c on brackets d. Each rod has two fixed pulleys g, e, h, f and two rotatable pulleys i, k. A cord o passes over one of the pulleys l, m and round the pulleys e, f, and a cord n passes round the other of the pulleys l, m and round the pulleys i, k. On pulling the cord o the arms swing outwards, and on pulling the cord n they are swung back. A curtain is carried on each arm a, b, and the long arm carries the cornice or other ornamentation.
Patent GB-189904712-A (GB)
Title: An Improved Process for Finely Dividing Mercury or Amalgam.
Inventor: BLOMQUIST ARVID NATANAEL
Filed: 1899-03-03
Granted: 1899-05-06
Abstract: 4712. Blomquist, A. N. March 3. Alloys; amalgamating; granulating or pulverizing. -Relates to a process for obtaining mercury or amalgams in a finely-divided state for use in making preparations of mercury. An amalgam is obtained by alloying mercury with aluminium, magnesium, barium, strontium, calcium, or lithium, by heating in presence of sodium or potassium hydrate. The amalgam thus obtaining is pulverized by grinding. If lithium or one of the metals of the alkaline earths is added to an aluminium or magnesium amalgam, it causes the mercury to be liberated in the preparation owing to gradual oxidation.