baber/WOPTO huggingface dataset:
Patent NZ-578560-A (NZ)
Title: 4-aryl-6-piperazin-1-yl-3-substituted-pyridazine derivatives that are fast dissociating dopamine 2 receptor antagonists useful in the treatment of central nervous system disorders
Inventor: MACDONALD GREGOR JAMES
IPC: A61K31/495
Filed: 2008-02-11
Abstract: Disclosed herein are 4-aryl-6-piperazin-1-yl-3-substituted-pyridazine compounds of formula (I), wherein the substituents are as defined in the specification, such compounds are fast dissociating dopamine 2 receptor antagonists which are useful in the treatment of central nervous system disorders such as schizophrenia by exerting an antipsychotic effect without motor side effects. Also disclosed are processes for preparing said compounds and pharmaceutical compositions comprising said compounds as an active ingredient.
Patent NZ-579108-A (NZ)
Title: Process for producing 1,3,-dioleoyl-2-palmitoyl glyceride (OPO)
Inventor: SCHWEITZER ERIK
IPC: A23L1/30
Filed: 2008-02-27
Abstract: A process for the production of a 1,3-dioleoyl-2-palmitoyl glyceride (OPO) comprising: providing one or more palm oil stearin fractions comprising tripalmitoyl glyceride and having an iodine value between about 18 and about 40; interesterifying the one or more palm oil stearin fractions to form randomly interesterified palm oil stearins; subjecting the randomly interesterified palm oil stearins to enzymatic transesterification with oleic acid or a non-glyceride ester thereof using an enzyme having selectivity for the 1- and 3- positions of a glyceride; and separating palmitic acid or palmitic non-glyceride esters from the products of the randomly interesterified palm oil stearins to form a composition comprising increased amounts of OPO glyceride.
Patent NZ-580206-A (NZ)
Title: A foundation interface assembly comprising a precast reinforced concrete block and a top plate
Inventor: GRIFFITHS MELVYN THOMAS
IPC: E02D27/42
Filed: 2010-12-22
Abstract: Disclosed is a foundation interface assembly for supporting a superstructure attached to the foundation interface assembly when the foundation interface assembly is placed on and attached to an underlying structure. The foundation interface assembly includes a precast concrete block, a block reinforcing structure and a top plate. The block is reinforced by the block reinforcing structure. The block reinforcing structure is partially embedded in the block during casting of the block. Portions of the block reinforcing structure extend above a top surface of the block for attachment to a base end of the superstructure to be supported by the foundation interface assembly. The block has a plurality of through-holes, each through-hole extends upwardly from a downward facing surface of the block, through the block, to an upward-facing surface of the block. The top plate is at the top surface of the block and has a plurality of through-holes. The portions of the block reinforcing structure which extend above the top surface of the block, extend respectively through the through-holes in the top plate for attachment to the base end of the superstructure to be supported by the foundation interface assembly.
Patent NZ-589464-A (NZ)
Title: Abdominal exercise device where the knees of the user swing in different arcs while supported on rests
Inventor: SPLANE ROBSON
IPC: A63B23/00
Filed: 2009-08-27
Abstract: An exercise device (100) suitable for abdominal and upper body exercises is disclosed. The device has a base (102) to position itself on the ground. Knee supports (108,106) which are bilaterally coupled to first and second pivots located off from the center of the base. Independently rotatable knee pads (112,110) are coupled to the perimeter-side end of the knee supports which are arranged around a perimeter (116) of the base. The knee supports move around different arcs to generate an elliptical motion for an individual. An upper extremity support (114) is coupled to the base. The base is able to be inclined to vary resistance.
Patent NZ-589963-A (NZ)
Title: Processes for the preparation of 6- beta-hydroxy morphinan compounds
Inventor: BAO JIAN
IPC: C07D489/02
Filed: 2009-06-16
Abstract: A process for preparing a compound, the process comprising: contacting a 6-keto morphinan compound represented by general formula (I) with a reducing agent and a first proton acceptor to form a first homogeneous reaction mixture, wherein some of the compound of general formula (I) is converted to a 6-hydroxy morphinan compound of general formula (II) to produce a substantially heterogeneous reaction mixture; and (b) contacting the heterogeneous reaction mixture with a second proton acceptor to form a second homogeneous reaction mixture, wherein some of the compound of general formula (I) that was not converted to compound (II) in step (a) is converted to compound (II).
Patent NZ-590966-A (NZ)
Title: Apparatus for actuating a main valve which allows the discharge of a pressurised fluid in response to a sensed event
Inventor: HODGES STEVEN EDWARD
IPC: A62C3/07
Filed: 2006-05-19
Abstract: An apparatus for actuating a main valve 18 is described. The main valve 18 has an exposed component that is moveable along a line of travel from a first position to a second position. The main valve 18 also has an actuated state in which the exposed component is in the second position and a non-actuated state in which the exposed component is in the first position. The apparatus has a pilot valve 20. The pilot valve 20 has housing and a piston 58 disposed within the housing and movable between a deactivated position and an activated position along a pathway. The piston 58 separates the housing into a first sealed chamber 74 and a second sealed chamber 76. The chambers are both sealed from air entry. The first sealed chamber 74 and the second sealed chamber 76 are connected by a fluid path with a flow restrictor that substantially limits the fluid flow through the path in a direction from the first sealed chamber 74 to the second sealed chamber 76. The piston 58 moves to the activated position in response to a pressure drop in the first sealed chamber 74. A first contact is connected to the piston 58 and moves with the piston 58. The first contact urges the exposed component of the main valve 18 from the first position to the second position as the piston 58 moves from the deactivated position to the activated position. A sensor 94 is connected to the first sealed chamber 74 and is adapted to vent a pressurized fluid from the first sealed chamber 74 in response to a sensed event.
Patent NZ-595513-A (NZ)
Title: Process for producing carboxylic acid compound
Inventor: MATSUMOTO KATSUYA
IPC: A61K31/235
Filed: 2010-03-25
Abstract: Disclosed herein is a method for the preparation of compound (I) which involves glycidylation of compound (II) to produce compound (III) which is subsequently reacted with compound (IV) to form compound (V), which can then be transform into compound (I) by alkali hydrolysis or transesterification followed by alkali hydrolysis wherein each compound is as follows: Compound I is 2'-((1R)-1-{ (2R)-3-[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-ylamino]-2-hydroxypropoxy} ethyl)-3-methylbiphenyl-4-carboxylic acid; Compound II is tert-butyl 3-methyl-2'-[(1R)-1-hydroxyethyl]biphenyl-4-carboxylate; Compound III is tert-butyl 3-methyl-2'-[(1R)-1-((R)-oxiranylmethoxy)ethyl]biphenyl-4-carboxylate Compound IV is 1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amine; and Compound V is tert-butyl 2'-((1R)-1-[(2R)-3-[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-ylamino]-2-hydroxypropoxy]ethyl)-3-methylbiphenyl-4-carboxylate.
Patent NZ-595790-A (NZ)
Title: Method for on-demand contraception
Inventor: GAINER ERIN
IPC: A61K9/20
Filed: 2010-04-13
Abstract: 595790 Disclosed herein a method for on-demand contraception, which method comprises administering 17?-acetoxy-11?-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20- dione (ulipristal acetate) or a metabolite thereof in a woman, within 72 hours before an intercourse or within 120 hours after the intercourse.
Patent NZ-599136-A (NZ)
Title: Substituted carbamoylmethylamino acetic acid derivatives as novel nep inhibitors
Inventor: IWAKI YUKI
IPC: A61K31/41
Filed: 2010-11-18
Abstract: 599136 Disclosed are carbamoyl substituted biphenyl compounds of formula (I) where the substituents are as disclosed in the specification. Examples of compounds of formula (I) are: (S)-2-[(S)-2-(3'-chloro-biphenyl-4-yl)-1-(1H-tetrazol-5-ylcarbamoyl)-ethoxy]-propionic acid ethyl ester; (S)-2-[(S)-2-(3'-chloro-biphenyl-4-yl)-1-(1H-tetrazol-5-ylcarbamoyl)-ethylamino]-propionic acid; (S)-2-[(S)-2-(3'-Chloro-biphenyl-4-yl)-1-(3-hydroxy-isoxazol-5-ylcarbamoyl)-ethylamino]propionic acid. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) and the use of a compound of formula (I) in the manufacture of a medicament for the treatment of a disorder or disease associated with neutral endopeptidase EC. 3.4. 24.11. activity; or for diseases or disorders such as hypertension, pain, inflammation and asthma.
Patent NZ-600651-A (NZ)
Title: Adherent cells from placenta and use of same in disease treatment
Inventor: ABERMAN ZAMI
IPC: A61K35/12
Filed: 2010-11-29
Abstract: Disclosed is the use of a population of adherent cells derived from a placenta, wherein the population comprises at least 70% adherent cells from a maternal portion of the placenta, wherein the maternal portion of the placenta is either or both of decidua basalis or decidua parietalis and wherein the adherent cells do not differentiate into osteogenic lineages in the manufacture of a medicament for treating a condition selected from muscle trauma, muscle defect, neuropathic pain, peripheral nerve injury, neurodegenerative disease.
Patent NZ-604301-A (NZ)
Title: Apparatus for breathing with hypoxic gaseous mixtures
Inventor: LOPATA VIKTOR
IPC: A61M16/22
Filed: 2010-10-07
Abstract: Disclosed is apparatus for breathing with hypoxic gaseous mixtures. The apparatus comprises of: a supporting frame; a respiratory reservoir equipped with an inspiration valve, a first sensor of oxygen content and an absorber of CO2 and H2O; a controllable compressor connected via puffing valve to the respiratory reservoir; and a chamber for sampling and accumulation of aliquots of expired gaseous mixtures equipped with a second sensor of oxygen content, controllable adjusting valve and controllable ejector. The apparatus also includes means for attachment to a user, such as a mask; an inspiration line comprising controllable centre valve and first inspiratory rate flowmeter; a tee fitting; main expiration line that is equipped with first air blower and connects said attachment with said reservoir; additional expiration line that is equipped with second flowmeter measuring volume of sampling aliquots and second air blower and connects said attachment with said chamber; and a supplementary sensor complex and program control unit. This apparatus provides for the estimation of minute oxygen consumption and, accordingly, efficiency of regulation of breathing with hypoxic gaseous mixtures.
Patent NZ-606260-A (NZ)
Title: Novel polypeptides involved in immune response
Inventor: YOSHINAGA STEVEN KIYOSHI
IPC: C07K14/725
Filed: 2000-01-27
Abstract: Disclosed is an antibody or fragment thereof, which binds to a polypeptide comprising the mature amino acid sequence of the polypeptide as set forth in SEQ ID NO: 17 or the mature amino acid sequence of the polypeptide as set forth in SEQ ID NO: 7.
Patent NZ-611635-A (NZ)
Title: Electronic lock with power failure control circuit
Inventor: BRYLA MARK
IPC: E05B49/00
Filed: 2011-12-09
Abstract: Disclosed is an electronic lock with power failure control circuit includes a lock mechanism having a latch bolt movable between extended and a retracted positions and an electrically powered lock actuator (22) to lock and unlock the latch bolt. The power failure control circuit includes a microcontroller (42) and the lock is connected to a primary power source and an auxiliary power source, preferably supercapacitors (20) and charger that can be turned on by the microcontroller (42) and off when the charger signals a full charge. A power monitor circuit (16) detects low voltage on the primary power supply (10) and sets a power failure interrupt causing the microcontroller (42) to execute power failure instructions that control the actuator (22) so that the lock is placed into a desired locked or unlocked final state during the power failure, upon detection of the return of good power, the system resets the lock. The power monitor circuit (16) including voltage thresholds related by hysteresis to prevent oscillation at or near transition points between the power failure state and the normal power state whereby upon detecting the power failure condition the electrically controllable switch circuit receives power from the auxiliary power supply to reduce power load on and enable recovery of the primary power supply (10), and once the primary power supply (10) has recovered the electrically controllable switch circuit switching power back to the primary power supply (10).
Patent NZ-612370-A (NZ)
Title: Ground cover material
Inventor: TOYE JONATHAN DALLAS
IPC: D06N7/00
Filed: 2012-04-26
Abstract: A ground cover sheet material (1) woven from warp and weft tapes is disclosed. The material comprises regions of relatively thicker warp tapes (11) and regions of relatively thinner warp tapes. The thicker regions are at or adjacent one or both longitudinally extending opposite side margins of the material, and one or more longitudinally extending centre regions near or adjacent a notional centre (30) or fold line of the material. The thinner regions make up the balance of the sheet material. By employing one or more thicker warp tape regions the centre of the sheet, the material can be rolled up more evenly to maintain a more even tension across the entire warp during the manufacturing process than if the thicker warp tapes were only on the side margin(s).
Patent NZ-613870-A (NZ)
Title: Pharmaceutical compositions comprising human antibodies to pcsk9
Inventor: HANOTIN CORINNE
IPC: C07K16/40
Filed: 2012-01-27
Abstract: Disclosed is pharmaceutical composition comprising 40 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 250 mg, 300 mg, 350mg, 400 mg, 450 mg or 500mg of an antibody or an antigen-binding fragment thereof which specifically binds human proprotein convertase subtilisin/kexin type 9 (hPCSK9) together with a pharmaceutically acceptable excipient or carrier, wherein the antibody or antigen-binding fragment thereof comprises the three heavy chain CDRs set forth in SEQ ID NOs: 76, 78, and 80 and the three light chain CDRs set forth in SEQ ID NOs: 84, 86, and 88; wherein the sequences are as defined in the specification.
Patent NZ-615942-A (NZ)
Title: Apparatus and method for using infrared thermography and behaviour information for identification of biologically important states in animals
Inventor: BENCH CLOVER
IPC: H04N5/33
Filed: 2012-03-28
Abstract: Disclosed is an apparatus for identifying biological states in an animal. The apparatus comprises means for identifying the animal (6) to obtain animal identification information, at least one infrared thermography camera (8) for photographing the animal to obtain infrared thermography information and fidget information about the animal and a processor (9) for receiving and processing the animal identification information. The infrared thermography information and the fidget information can be used to determine a biological state of the animal. The biological state is a predictor of onset of disease, growth states and reproductive states in the animal.
Patent NZ-616957-A (NZ)
Title: Hemostatic compositions and therapeutic regimens
Inventor: FINKIELSZTEIN SERGIO
IPC: C08L5/08
Filed: 2008-02-19
Abstract: Disclosed is a composition comprising shortened poly-β-1→4-Nacetylglucosamine fibers, wherein the shortened fibers have been produced by irradiating poly-β-1→4-N-acetylglucosamine fibers with a dose of irradiation, and wherein (i) the length of greater than 50% of the shortened fibers is less than about 15 μm in length or (ii) the average length of the shortened fibers is less than about 15 μm in length.
Patent NZ-617768-A (NZ)
Title: Process for preparing a cobalt - containing hydrocarbon synthesis catalyst precursor
Inventor: VISAGIE JACOBUS LUCAS
IPC: C07C1/04
Filed: 2012-04-25
Abstract: Disclosed is a process for preparing a cobalt-containing hydrocarbon synthesis catalyst precursor, which process includes calcining a loaded catalyst support comprising a catalyst support supporting a cobalt salt, the calcination involving decomposing the cobalt salt and/or causing the cobalt salt to react with oxygen, the calcination converting the cobalt salt into a cobalt oxide, and the calcination including subjecting the loaded catalyst support to heat treatment by heating the loaded catalyst support to a temperature, T, of 220°C at a heating rate below 10°C/minute; and effecting gas flow at a space velocity of at least 19m3n/kg cobalt salt/hour over the loaded catalyst support during at least part of the heating to the temperature T of 220°C, thereby to produce the cobalt-containing hydrocarbon synthesis catalyst precursor.
Patent NZ-618670-A (NZ)
Title: Process and apparatus for continuous production of densified charcoal
Inventor: DEEV ALEXANDRE VLADIMIROVICH
IPC: C10B49/02
Filed: 2012-06-21
Abstract: Disclosed herein is an apparatus and a process for the continuous production of densified charcoal from organic material. The apparatus comprises a reaction vessel (1) for supporting a reaction bed of organic material, a material feeder (2) for supplying organic material to the reaction vessel (1), a heating zone (23) for drying the organic material, a plunger or pressure applicator (6) for compacting the reaction bed, acoustic emission devices (10 and 21) for assisting with the compaction of the reaction bed, a reaction zone (24) for autogenous reaction of organic material in the reaction bed, a cooling zone (25) to reduce the temperature of the material, and a discharge port (17) for discharging carbonised organic material from the reaction vessel (1). The apparatus has a decreasing cross sectional area in the vicinity of the reaction zone (24) which tapers inward towards the discharge end of the vessel and also comprises a lance (15) which extends from the discharge end of the reaction vessel (1) into the reaction zone (24) which contains vapour extraction vents (20) to remove vapour generated in the reaction zone (24). The densified charcoal produced from organic material by the disclosed apparatus and process method is suitable as chemical reagents, fuels, or absorbents.
Patent NZ-620692-A (NZ)
Title: A system and a process to produce low ash clean coal from high ash coal
Inventor: VIMAL KR CHANDALIYA
IPC: C10L9/00
Filed: 2011-09-01
Abstract: Disclosed herein is an industrial process for treating coal to lower ash content in a system, the system comprising a first water storage tank (1), a second water storage tank (2), a diesel storage tank (3), a thermic fluid heater (4), a thermic fluid storage tank (5), a thermic fluid pump (6), a heat exchanger (7), a thermic fluid expansion tank (8), a N2 gas cylinder (9), a reactor (10), a water pump (11), and a reflux condenser (12), the method comprising (i) forming a slurry of coal fines in N-Methyl-2-pyrrolidone (NMP) and Ethylenediamine (EDA) solvents, the NMP and EDA ratio varying between 5:1 to 25:1 solution, said slurry containing about 6 to 18 ml of solution per g of coal, (ii) maintaining said slurry in the reactor at a temperature range of 150°C to 220°C and at a pressure range of 1 to 4 gauge (kg/cm ) for a period of about 1 to 3 hours, (iii) separating a sample of the slurry by coarse filtration in a filter cloth, (separation cut size being variable depending on the particle size to be treated and the end produce), to obtain a filtrate or extract and a residue, (iv) precipitating the coal in water by adding concentrated extract, and (v) separating the coal by filtration, said coal having a reduced ash content of less than 8%.
Patent NZ-621592-A (NZ)
Title: Methods for tagging dna-encoded libraries
Inventor: KEEFE ANTHONY D
IPC: C40B50/16
Filed: 2012-09-07
Abstract: A method of tagging a first library comprising an oligonucleotide-encoded small molecule or peptide is disclosed. A headpiece having a first functional group and a second functional group is provided in step (i). The headpiece comprises at least one 2’-substituted nucleotide and the headpiece comprises a 2’-substituted nucleotide at the 5’-terminus and/or 3’-terminus. In step (ii) the first functional group of the headpiece is bound to a first component of the small molecule or peptide. The headpiece is directly connected to the first component or the headpiece is indirectly connected to the first component by a bifunctional linker; and in step (iii) the second functional group of the headpiece is bound to a first building block tag to form a complex. The steps (ii) and (iii) can be performed in any order and the first building block tag encodes for the binding reaction of the step (ii), thereby providing a tagged library. A complex comprises a headpiece and a building block tag. The tag comprises from 5 to 20 nucleotides, a 2’-substituted nucleotide at the 5’-terminus, and a 2’- substituted nucleotide at the 3’-terminus and the headpiece is directly connected to a small molecule or peptide or the headpiece is indirectly connected to a small molecule or peptide by a bifunctional linker.
Patent NZ-701115-A (NZ)
Title: Cobalt nanoparticle adjuvant
Inventor: HOWIE SARA
IPC: C01G51/04
Filed: 2013-03-15
Abstract: The present invention is based on the identification of the adjuvant properties of inorganic (metal/metal oxide) nanoparticles. As such, the invention provides an adjuvant comprising, consisting or consisting essentially of, inorganic nanoparticle. The invention also provides compositions and vaccines comprising the same as well as methods which exploit the adjuvant inorganic nanoparticles.
Patent NZ-722191-A (NZ)
Title: Pressure sensor evaluation for respiratory apparatus
Inventor: KENYON BARTON JOHN
IPC: G01L27/00
Filed: 2013-06-27
Abstract: Disclosed is a respiratory apparatus (100) for providing therapy for a patient with disordered breathing. The respiratory apparatus (100) comprises a flow generator (120), one or more sensors and a processor (116). The flow generator (120) has a blower (130) to generate a flow of breathable gas for a patient interface at a pressure above atmospheric pressure. The blower (130) comprises a motor. The one or more sensors (104, 106, 108, 110) are configured to respectively output measurement of one or more of: a) a pressure of the flow of breathable gas; b) a temperature of the flow of breathable gas; c) a speed of the motor; and d) a flow rate of the flow of breathable gas. The processor (116) comprises an altitude estimation unit. The processor (116) is configured to determine an estimate of an altitude of the respiratory apparatus (100) based on the output measurement from the one or more sensors. And the processor (116) is also configured to control the blower (130) based on the estimate of the altitude.
Patent NZ-725991-A (NZ)
Title: Composition comprising a biological control agent and a fungicide
Inventor: WACHENDORFF-NEUMANN ULRIKE
IPC: A01N31/04
Filed: 2013-05-29
Abstract: The present invention relates to a composition comprising at least one biological control agent selected from the group consisting of Bacillus subtilis AQ713 (NRRL Accession No. B-21661) and Bacillus subtilis AQ30002 (NRRL Accession No. B-50421), and at least one fungicide (I) which is acibenzolar-S-methyl in a synergistically effective amount wherein the synergistic weight ratio of biological control agent and fungicide (I) is between 1:0.0001 and 1:1. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.