baber/WOPTO huggingface dataset:
Patent CA-2375921-C (CA)
Title: Modele murin du syndrome de goodpasture
Inventor: TAKAI TOSHIYUKI
IPC: A61P11/00
Filed: 2000-06-23
Granted: 2006-08-01
Abstract: Cette invention a trait à un modèle animal du syndrome de Goodpasture contribuant au traitement de cette maladie dont le développement de la thérapie a été retardé du fait du manque de modèles adaptés. L'invention porte également sur une méthode de criblage de remède contre le syndrome de Goodpasture utilisant le modèle animal ainsi que sur une méthode de diagnostic de ce syndrome à un stade précoce. On immunise une souris présentant une déficience du récepteur IIB membranaire du fragment fc de l'immunoglobuline (fc gamma ) à l'aide de collagène de type IV et ce, afin d'induire le syndrome de Goodpasture. Cette opération permet de produire un modèle murin du syndrome de Goodpasture. On administre ensuite des substances d'essai au modèle murin et l'on procède au criblage d'un remède contre le syndrome de Goodpasture d'après l'évaluation de la gravité de l'expression dudit syndrome (c'est-à-dire hémorragie alvéolaire diffuse, glomérulonéphrite, apparition d'anticorps membrane basale glomérulaire antirénal, etc.).
Patent CA-2385415-C (CA)
Title: Compositions pour reguler le desir de fumer
Inventor: OKUBO TSUTOMU
IPC: A61K31/198
Filed: 2001-07-18
Granted: 2008-01-29
Abstract: La présente invention concerne des compositions de sécurité non anaclitiques permettant de réguler le désir de fumer. En l'occurrence, ces compositions permettent (1) une régulation du désir tabagique dans les situations non tabagiques de la vie quotidienne, (2) l'arrêt ou la réduction volontaire de la consommation tabagique, et (3) l'abandon total de l'habitude de fumer. L'invention concerne également un procédé d'arrêt ou de réduction de la consommation tabagique par administration aux sujets concernés de compositions contenant de la théanine.
Patent CA-2392645-C (CA)
Title: Extensible device command commutation engine
Inventor: WHEDBEE KENNETH C JR
IPC: G06F9/45
Filed: 2001-01-04
Granted: 2007-06-05
Abstract: An extensible commutation engine (1) connected to a command database (6) for formatting a command buffer via command interface (5) in a device commanding system comprises: a modifiable list of constants, each constant forming a coded representation of parameters associated with a device command, at least one set of instructions for formatting the command buffer in accordance with a device command using a command formatter (2), and a modifiable mapping of each set of instructions with a corresponding constant. In addition, the commutation engine is extensible to accommodate device commands having new parameters via mapping of new constants with a set of instructions according to said new parameters. The commutation engine can be used to provide application specific output (4) for use in controlling various devices (7).
Patent CA-2392651-C (CA)
Title: Multi-blade cutting device
Inventor: SILVER MICHAEL I
IPC: B26B13/00
Filed: 2001-04-04
Granted: 2004-01-13
Abstract: A cutting device especially designed for cutting up salad greens includes tw o blades (110), a rib (12) and handles (103, 105). The two blades are inter- secured to rotate together about a common axis (101), but are spaced apart from each other along the common axis. The rib (12) is pivotably secured to the two blades so as to rotate about the common axis, and is curved in a direction of rotation so as to have a concave surface. The handles are integrated with the two blades and the rib to control the two blades and the rib to rotate simultaneously between open and closed positions. The concave surface of the rib is the lead surface when moving from the open position to the closed position, and the cutting edges of the two blades cross edges of the concave surface when moving from the open position to the closed positio n, so as to perform a cutting action.
Patent CA-2394694-C (CA)
Inventor: OHTA MASATAKA
IPC: F23R3/16
Filed: 2002-07-23
Granted: 2008-04-15
Abstract: A pilot nozzle of a gas turbine combustor comprises a first structure, provided near a main nozzle of a combustor that injects fuel oil, having a flow channel for a fuel gas and an outlet for the fuel gas. The first structure diffusion-injecting the fuel gas obliquely forward through the outlet to maintain a flame and to aid ignition of the fuel oil injected from the main nozzle. There is further provided a second structure which circulates in whirls a combustion gas generated due to the combustion of the fuel gas.
Patent CA-2395196-C (CA)
Title: Cyclic amp-specific phosphodiesterase inhibitors
Inventor: GAUDINO JOHN J
IPC: A61P17/06
Filed: 2000-12-15
Granted: 2006-02-21
Abstract: Novel compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases an d other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.</SDOAB >
Patent CA-2401821-C (CA)
Inventor: STRANIX BRENT RICHARD
IPC: A61K31/395
Filed: 2001-03-07
Granted: 2013-05-21
Abstract: The present invention relates to a class of amino acid derivatives with HIV  aspartyl protease inhibitory properties.
Patent CA-2404743-C (CA)
Inventor: BAUMBERG JEREMY JOHN
IPC: G02F1/31
Filed: 2001-04-06
Granted: 2011-10-25
Abstract: In order to create an optical device with a photonic band gap extending in two dimensions and with very uniform properties in any direction and for any polarisation state, to within 1 %, air holes are etched within a substrate of low refractive index material such silicon oxynitride or silica glass. The ratio of air hole area to the remainder of the substrate is low, being less than 35 %. The air holes define a quasicrystal structure, having twelve fold symmetry, being based on a square-triangle system. In another development, an etched substrate with a regular crystal structure or quasicrystal structure exhibits a non-linear refractive index. Two adjacent areas in such a substrate have different lattice properties, or have defects in the lattices, to create a unidirectional transmission path (diode action). A further beam of light may be used to modulate the transmission path by reason of the non-linear refractive index.
Patent CA-2404948-C (CA)
Title: Adjustable pedal mechanism for a motor vehicle
Inventor: PATON GORDON ANDREW
IPC: G05G1/323
Filed: 2001-04-09
Granted: 2009-08-04
Abstract: An adjustable pedal assembly for a motor vehi-cle includes a bracket for mounting the adjustable pedal assembly to the motor vehicle. A pivot link is pivotally mounted to the bracket. The pivot link has a first guide slot and a first pin. A  pedal is pivotally secured to the pivot link and includes an arm.  The arm has a second guide slot and a second pin. The second guide slot works in conjunction with the first pin whereas the first guide slot works in conjunction with the second guide pin.  Together, these pairings define the relative movement between the pivot link and the pedal arm. A drive assembly extends be-tween said first pin and said second pin. The drive assembly slides the pedal arm relative to the pivot link to extend and re-tract the pedal with respect to the operator.
Patent CA-2408368-C (CA)
Inventor: FRY EMANUEL D
IPC: F04B39/02
Filed: 1998-11-06
Granted: 2004-11-02
Abstract: A compressor assembly includes a compressor mechanism mounted within a hermetically sealed housing. The housing is effectively divided into a low pressure area at a relatively low temperature and a high pressure area at a relatively high temperature. A motor and a lubrication system are contained within the low pressure area and the discharge side of the compressor mechanism is disposed in the high pressure area. A cylinder block effectively separates the high and low pressure areas of the compressor. The lubrication system includes an axial passage for communication oil from a sump to various compressor components, including rotational bearings. A seal cap is disposed at the end of the crankshaft that extends into the high pressure area and in combination with the cylinder block defines an oil discharge chamber at low pressure and isolated from the high pressure area. A  second vent passage formed in the upper end portion of the crankshaft provides a communication path between a suction cavity formed in the compressor mechanism and the oil discharge chamber within the seal cup. A pressure drop caused by the reciprocating action of the pistons in the compressor mechanism occurs at the oil discharge area formed in the seal cup thereby assisting the oil pump in drawing oil through the oil passage in the crankshaft. An acoustic insulator is provided intermediate the compressor mechanism and a mounting flange to isolate and reduce vibration and noise which occurs during compressor operation.
Patent CA-2409894-C (CA)
Title: Tracked vehicle
Inventor: KANZLER HELMUT
IPC: B62D11/18
Filed: 2002-10-28
Granted: 2010-10-26
Abstract: A tracked vehicle with a drive system, which. performs driving, braking, directional change, and steering functions as a function of corresponding control commands from an electronic control unit. According to the invention; at least one separate brake system, which operates without current, is provided, which can be enabled by at least one actuating element, which also acts in the absence of current, when a function parameter exceeds or falls below at least one limit value.
Patent CA-2412915-C (CA)
Title: Procede de detection qualitative et/ou quantitative d'interactions moleculaires sur des microplaques
Inventor: ERMANTRAUT EUGEN
IPC: C12Q1/6837
Filed: 2001-07-02
Granted: 2009-04-21
Abstract: L'invention concerne un dispositif et un procédé de détection qualitative et/ou quantitative de cibles moléculaires déterminées au moyen de microplaques. Conformément au procédé de l'invention, la détection s'effectue par une réaction fournissant un produit présentant un produit de solubilité déterminé, ce qui entraîne une précipitation, ou la formation d'un précipité du produit sur un élément des microplaques sur lequel a eu lieu une interaction entre la microplaque et la cible.
Patent CA-2418450-C (CA)
Title: Conteneur superposable avec rebords de soutien
Inventor: KANTER ALLEN
IPC: B65D5/02
Filed: 2003-02-04
Granted: 2007-01-30
Abstract: Un conteneur est présenté comportant une pluralité de panneaux interconnectés formant des parois latérales entourant un espace central. Des volets s'étendent des bords de la paroi latérale inférieure et se plient le long de lignes de pliure pour former un fond. Des brides de soutien sont disposées le long des parois latérales supérieures sur les parois se faisant face de manière opposée. Les brides de soutien sont orientées à angles droits par rapport au trottoir et offrent une surface de support permettant aux conteneurs d'être empilés les uns sur les autres sans s'écraser ou s'emboîter les uns sur les autres. Chaque bride de soutien est supportée par une ferme formée par un segment de panneau s'étendant à angle à partir de la bride de soutien vers un panneau de soutien reposant contre la paroi latérale à laquelle la bride de soutien est fixée par un rabat de retenue s'étendant d'une couche de paroi latérale interne. Les pattes de blocage aux extrémités de chaque segment de panneau sont logées dans les creux positionnés sur les panneaux de la paroi latérale perpendiculaires aux brides de soutien. Le conteneur est formé à partir d'une découpe formée à partir d'un blanc unitaire.
Patent CA-2420334-C (CA)
Title: Polarization recovery system for projection displays
Inventor: LI KENNETH K
IPC: G02F1/13
Filed: 2001-07-30
Granted: 2008-10-28
Abstract: A waveguide polarization recovery system both polarizes the input light ener gy for use with an LCD imager and converts the polarity of unusable light energ y to add to the illumination of the LCD imager. The compact polarization recovery waveguide system generally includes: (1) an input waveguide that provides non-polarized light energy into the system; (2) an output waveguide that receives polarized light energy from the system; (3) a polarized beam splitter that received the light energy from the input waveguide and transmi ts lights energy of a first polarization type and reflects light energy of a second polarization type, and (4) a wave plate that modifies the polarizatio n of either the transmitted or reflected light energy. The polarization recove ry system also generally includes one or more mirrors that are positioned as ne ed to direct the transmitted and the reflected light energy to the output waveguide.
Patent CA-2422890-C (CA)
Title: Methode de prediction de la reaction clinique a un traitement chimiotherapeutique avec des agents alkylants
Inventor: BAYLIN STEPHEN B
IPC: C12Q1/683
Filed: 2001-10-01
Granted: 2013-04-23
Abstract: L'invention concerne des méthodes liées au traitement chimiothérapeutique d'un trouble de la prolifération cellulaire. L'invention concerne notamment une méthode permettant de prédire la réaction clinique à certains types d'agents chimiothérapeutiques. Les agents alkylants, utilisés pour le traitement de certains types de tumeurs parmi lesquelles des tumeurs du système nerveux et du système lymphatique, sont des agents efficaces lorsque les dommages qu'ils causent à l'ADN de cellules tumorales ne sont pas réparés par les mécanismes de réparation de l'ADN cellulaire. L'invention concerne en outre une méthode permettant de déterminer l'activité d'un gène codant pour une enzyme de réparation de l'ADN, fournissant ainsi une prédiction de la réaction clinique à des agents alkylants.
Patent CA-2429105-C (CA)
Inventor: HONG EUGENE
IPC: A01K89/01
Filed: 2003-05-16
Granted: 2006-08-08
Abstract: A fishing spinning reel includes a rotating member disposed rotatably in a reel frame about a first axis, and a coupling member disposed movably in the reel frame and connected to a reciprocating spool spindle. A cam member has a first cam end loosely engaging a slot in the rotating member to be movable along a non-circular path defined by a non-circular guideway, and a second cam end engaging a cam follower of the coupling member. When the first cam end is moved by rotating movement of the rotating member through a handle, the coupling member and the spindle reciprocate along a second axis perpendicular to the first axis.
Patent CA-2430696-C (CA)
Title: Derives phenylethenyle ou phenylethinyle servant d'antagonistes de recepteur de glutamate
Inventor: WICHMANN JUERGEN
IPC: C07D231/12
Filed: 2001-11-26
Granted: 2009-01-27
Abstract: L'invention concerne l'utilisation de composés de la formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ possèdent la signification donnée dans le descriptif ; A est -CH=CH- ou -C=C- ; B est B1), B2), B3), B4), B5) ou B6) ; et R?6¿ à R?26¿, et X et Y possèdent la signification donnée dans le descriptif, ainsi que l'utilisation des sels pharmaceutiquement acceptables desdits composés dans la fabrication de médicaments destinés au traitement ou à la prévention de maladies liées au récepteur de mGluR5.
Patent CA-2435280-C (CA)
Title: Chemiluminescent solution based on disubstituted perylene tetracarboxylic acids, their dianhydrides and diimides
Inventor: CRANOR EARL
IPC: C09K11/07
Filed: 2002-01-14
Granted: 2010-08-10
Abstract: Compositions adapted to be reacted with hydrogen peroxide to provide chemiluminescent light are disclosed wherein the fluorescent is selected from 1,7-disubstituted perylene-3,4-9, and 10-tetracarboxylic acids, their dianhydrides and diimides.
Patent CA-2437381-C (CA)
Inventor: WATSON EDWARD B III
IPC: B01J20/24
Filed: 2002-01-31
Granted: 2012-03-27
Abstract: An affinity matrix for use in affinity based molecular pull down and immunoprecipitation procedures. The affinity matrix comprises a polymeric support, a dye attached to a fraction of the polymeric support to enable optical detection of the polymeric support, and an affinity ligand other than the dye attached to a fraction of the polymeric support for the capture of a molecule. Also provided is a method for the isolation of a biomolecule from an aqueous solution. The method comprises combining the aqueous solution with an affinity matrix comprising a polymeric support and separating the affinity matrix from the aqueous solution. A dye is attached to a fraction of the polymeric support which enables optical detection and monitoring of the affinity matrix and, accordingly, reduces the likelihood of the loss of affinity matrix during the separation step. In addition, an affinity ligand other than the dye is also attached to a fraction of the polymeric support for the capture of the biomolecule.
Patent CA-2459089-C (CA)
Inventor: HABERMEHL G LYLE
IPC: B25B23/04
Filed: 2004-02-26
Granted: 2010-06-15
Abstract: Bande de vis courbe qui comprend une attache en plastique combinée à une pluralité d'éléments de fixation filetés. La masse de la moitié supérieure de l'attache est supérieure à celle de la moitié inférieure, de sorte que le retrait consécutif à l'extrusion tend à conférer à l'attache une conformation courbe préférée.
Patent CA-2459562-C (CA)
Inventor: SEIFERT JOACHIM
IPC: C07H3/04
Filed: 2002-09-06
Granted: 2013-05-07
Abstract: Preparation of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids.
Patent CA-2463153-C (CA)
Inventor: SWEARINGEN DEAN D
IPC: H01R13/415
Filed: 2002-10-18
Granted: 2008-01-29
Abstract: L'invention concerne un connecteur électrique (62, figure 88) et son procédé de fabrication. Ledit connecteur comprend un alésage (68, figure 88) qui s'étend depuis une première extrémité ouverte (66, figure 9) d'un logement jusqu'à une seconde extrémité opposée (70, figure 9). Un contact électrique est formé par une pluralité de bandes de contact présentant des extrémités décalées angulairement opposées et fixées fermement en contact électrique avec ledit logement dans la position angulairement décalée par un point d'ancrage d'extrémité intérieur (figures 25-89) et un point d'ancrage d'extrémité extérieur (figures 9-24). Selon un aspect, des crans sont formés dans au moins une des bandes de contact, de façon à entrer en prise avec un évidement complémentaire dans un élément conducteur pouvant être inséré dans la cavité, et à être mis en contact afin de retenir de manière libérable l'élément conducteur dans le logement.
Patent CA-2463503-C (CA)
Title: Procede et appareil de traitement aux uv de liquides aqueux
Inventor: HALLETT RONALD C
IPC: B08B9/00
Filed: 2002-10-11
Granted: 2012-12-11
Abstract: L'invention concerne un procédé et un appareil de traitement de liquide pressurisé. L'appareil comprend une chambre (16) de traitement de liquide pressurisé pourvue d'une fenêtre (18) laissant passer la lumière UV; une source (14a, 14b) de lumière UV en dehors de la chambre servant à émettre la lumière UV dans la chambre; un arbre (24) s'étendant entre les extrémités d'entrée et de sortie de la chambre et tournant autour d'un axe central de la chambre; un élément de nettoyage flexible (30) fixé à l'arbre et venant en contact avec une surface intérieure de la fenêtre (18); et au moins un élément (36) s'étendant radialement de l'arbre dans la chambre (16) de traitement afin d'interrompre le flux d'eau axial dans la chambre.
Patent CA-2473411-C (CA)
Title: Dispersions aqueuses stabilisees de polyurethanne-polyuree
Inventor: RISCHE THORSTEN
IPC: D06M13/402
Filed: 2003-01-10
Granted: 2011-03-22
Abstract: L'invention concerne des dispersions aqueuses de polyuréthanne/polyurée, stabilisées contre le jaunissement thermique, ainsi que leur production et leur utilisation.
Patent CA-2480062-C (CA)
Title: Aqueous two-component polyurethane systems
Inventor: PROBST JOACHIM
IPC: C08G18/66
Filed: 2003-03-12
Granted: 2011-08-09
Abstract: The invention relates to aqueous two component polyurethane systems comprising vinyl polymer polyol dispersions modified with reactive diluents, to a process for preparing them and to use as coating materials.
Patent CA-2482235-C (CA)
Title: Ice-crusher
Inventor: MARZARO NEREO
IPC: F25C5/04
Filed: 2004-09-21
Granted: 2012-08-07
Abstract: An ice-crusher (10) comprises a grinding hole (15) which includes a feeding collar (16) to which a lever (18) is hinged to push ice into the cutting area; the cutting unit includes a rotating disc (23) to which a cutting blade (25) is attached. The distance of the cutting blade (25) from the disc (23) can be set axially by the user and from outside the covering (13) of the ice-crusher (10) by means of a regulating key to break up ice into pieces of different thickness. Moreover, the manifold motor (34) of the device is positioned horizontally and is staggered relative to the shaft (26). Said motor (34) transmits motion to the shaft (26) by means of a belt (39) to leave room for inserting into the device (10) the key for regulating the thickness.
Patent CA-2485113-C (CA)
Title: Hydrophobically modified polymers containing vinylamine units or ethylenimine units, method for the production thereof, and their use as retention agents
Inventor: GRIMM GUNTHER
IPC: C08F8/00
Filed: 2003-05-19
Granted: 2011-04-26
Abstract: The invention relates to hydrophobically modified polymers, which contain vinylamine units or ethylenimine units and can be obtained by reacting: (a) polymers containing vinylamine units or ethylenimine units with; (b) compounds of formula (I) R - A - (EO, PO, BuO)n - X, in which: R represents C4 to C26 alkyl or C4 to C26 alkenyl; A represents O, NH, COO; EO represents an ethylene oxide unit; PO represents a propylene oxide unit, BuO represents a butylene oxide unit, n ranges from 1 to 250, and; X represents a functional group that can be covalently bonded to an OH group. The invention also relates to a method for producing hydrophobically modified polymers, which contain vinylamine units or ethylenimine units, by reacting polymers containing vinylamine units or ethylenimine units with at least one hydrophobing agent of formula (I), and to the use of polymers obtained in this manner as an additive to paper pulp during the production of paper.
Patent CA-2486915-C (CA)
Inventor: KWAK TAE HWAN
IPC: A61K45/00
Filed: 2003-05-28
Granted: 2011-03-08
Abstract: Provided is a composition that contains, as an active ingredient, an extract or polysaccharides separated from the leaves and/or stems of plants belonging to Panax genus, for an anticancer drug or its adjuvant, having an effect on the activity of hemotopoiesis enhancement, cancer metastasis inhibition, bone marrow defense, etc~, and a process for preparation of the extract from the leaves and/or stems of plants belonging to Panax genus.
Patent CA-2492709-C (CA)
Title: Process for the preparation of crystalline nano-particle dispersions
Inventor: SKANTZE TOMMY URBAN
IPC: C09K23/52
Filed: 2003-07-14
Granted: 2012-01-24
Abstract: A process for the preparation of a dispersion of crystalline nano-particles in an aqueous medium comprising combining (i) a first solution comprising a substantially water-insoluble substance in a water-miscible organic solvent with; (ii) an aqueous phase comprising water and optionally a stabiliser, to form a dispersion of amorphous particles; and (iii) sonicating the dispersion of amorphous particles for a sufficient period to form crystalline nano-particles of the substantially water-insoluble substance. The process provides nano-crystals with a mean hydrodynamic diameter of less than 1 micron, particularly less than 300 nm and is particularly useful for the preparation of nano-crystalline dispersions of pharmaceutical substances.