baber/WOPTO huggingface dataset:
Patent NZ-334548-A (NZ)
Title: Azinyloxy, and phenoxy-diaryl-carboxylic acid derivatives, their preparation and use as mixed eta/etb endothelin receptor antagonists
Inventor: AMBERG WILHELM
IPC: C07C69/734
Filed: 1997-09-02
Abstract: These carboxylic acid derivatives have the formula (I), in which R1 stands for tetrazole or a group (a); R2 stands for hydrogen, hydroxy, NH2, NH(C1-4-alkyl), N(C1-C4-alkyl)2, halogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkinyl, C1-C4-halogenalkyl, C1-C4-alkoxy, C1-C4-halogenalkoxy or C1-C4-alkylthio, or CR2 is linked with CR10, as indicated below, into a 5- or 6-membered ring; X stands for nitrogen or methine; Y stands for nitrogen or methine; Z stands for nitrogen or CR10, wherein R10 is hydrogen or C1-C4-alkyl or CR10 forms together with CR2 or CR3 an optionally substituted 5- or 6-membered alkylene or alkenylene ring, and wherein one or more methylene groups can be substituted by oxygen, sulphur, -NH or -N(C1-C4-alkyl); R3 stands for hydrogen, hydroxy, NH2, NH(C1-C4-alkyl), N(C1-C4-alkyl)2, halogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkinyl, C1-C4-hydroxyalkyl, C1-C4-halogenalkyl, C1-C4-alkoxy, C1-C4-halogenalkoxy, C1-C4-alkylthio; or CR3 is linked to CR10 as indicated above into a 5- or 6-membered ring, R4 and R5 (which may be identical or different) stand for optionally substituted phenyl or naphthyl, or for phenyl or naphthyl which are linked to each other at the ortho-position by a direct bond, a methylene, ethylene or ethenylene group, an oxygen or sulphur atom or an SO2, NH or N-alkyl group; optionally substituted C3-C8-cycloalkyl; R6 stands for optionally substituted C3-C8-cycloalkyl; optionally substituted phenyl or naphthyl, a 5- or 6-membered, optionally substituted heteroaromatic compound containing one to three nitrogen atoms and/or one sulphur or oxygen atom; W stands for sulphur or oxygen; Q is a spacer with a length that corresponds to a C2-C4 chain. Also disclosed are the physiologically tolerable salts of these compounds, as well as their pure enantiomer and diastereoisomer forms, their preparation and use as mixed ETA/ETB-receptor antagonists.
Patent NZ-334693-A (NZ)
Title: Cigarette comprising a filter having a highly porous peripheral surface and a tubular band of impervious material to render the cigarette smokable
Inventor: MATTEAU ROBERT
IPC: A24D1/00
Filed: 1997-08-22
Abstract: A non-smokable tobacco product comprises a rod-shaped tobacco element 11 coaxially interconnected to a rod-shaped filter element 12 with respective first ends of the elements adjoining.  A tubular wrapper 13 of smokable material encloses the tobacco element.  The first end of the filter element is wrapped by and adhered to a circumferential strip of material that is carried by the tobacco element.  The filter element has a peripheral surface that is highly porous thus rendering the product unsmokable in that when air is drawn from the product through the second free end of the filter element, the major portion of such air is drawn through the peripheral surface and any air flow drawn longitudinally through the tobacco element is insufficient to propagate combustion at the tip end thereof or to cause any appreciable amount of smoke to flow through the filter element to the second end thereof.  A preformed tubular band 20 of flexible substantially impervious material having a width corresponding to that of the highly porous surface of the filter element, and a circumference corresponding to that of the product is slidable on the product to a position overlying the highly porous peripheral surface to render the product smokable.
Patent NZ-502763-A (NZ)
Title: 4-cyano-4-deformylsordarin derivatives
Inventor: NIELSEN-KAHN JENNIFER
IPC: C12P1/02
Filed: 1998-08-18
Abstract: Described are 4-cyano-4-deformylsordarin derivatives of the formula (I) wherein Z is a tertrahydropyrano group selected from the group of compounds with the formulas (II) -(VII). These compounds are used in the preparation of pharmaceutical and agricultural compositions useful as antifungal agents and in the treatment and/or prevention of human and animal fungal infections, as well as in the control of phytopathogenic fungi in crops.
Patent NZ-504698-A (NZ)
Title: Microfluidic systems with cross-secting channels of different depths
Inventor: PARCE WALLACE J
IPC: G01N27/447
Filed: 1997-06-25
Abstract: Material flowing in the capillary channel 824 of a sampling micropipettor is flowed into the end of a microfluidic channel 814 of a microfluidic device with intersecting microfluidic channels.
Patent NZ-509728-A (NZ)
Title: Metabolically engineered microbial cell with an altered metabolite production by having altered enzyme activity controlling assimilation of nitrogen
Inventor: NIELSEN JENS
IPC: C12P7/06
Filed: 1999-07-12
Abstract: A recombinant microbial cell comprises at least one increased expressible enzyme activity controlling anabolic metabolism of ammonia in the cell and a reduced or eliminated expressible enzyme activity controlling anabolic metabolism of ammonia in the cell. The increased enzyme activity is a NADH-dependant activity catalyzing the reaction: 2-oxoglutarate + NH3 + NADH ® glutamate + NAD, 2-oxoglutarate + glutamine + NADH ® 2 glutamate + NADP, or 2-oxoglutarate + NH3 + ATP ® glutamine + ADP + Pi. The increased activity is that of an enzyme encoded by a nucleic acid coding sequence linked to an expression signal not natively associated with the nucleic acid coding sequence and is increased as compared to the expression of the enzyme activity when the nucleic acid coding sequence is associated with its native expression signal. The reduced or eliminated enzyme activity is a natively present NADPH-dependant glutamate dehydrogenase activity and is reduced compared to the native level of activity or eliminated. Preferably the increased expressible enzyme activity is provided by either glutamate synthase, glutamine synthase, or glutamate dehydrogenase from Saccharomyces cerevisiae. Further described is the production of metabolites by cultivating the microbial cell wherein the metabolites may be ethanol and glycerol.
Patent NZ-512398-A (NZ)
Title: Colchinol derivatives as vascular damaging agents
Inventor: DAVIS PETER DAVID
IPC: C07C301/02
Filed: 1999-12-24
Abstract: The invention relates to the use of compounds of formula (I): wherein X is -C(O)-, -C(S)-, -C=NOH, or - CH(R7; R1, R2 and R3 are as defined herein and are preferably methyl; R4, R5 and R6 are as defined herein with the proviso that R5 is not hydroxy, alkoxy, substituted alkoxy, -OPO3H2, -O-C1-7alkanoyl or benzyloxy; and salts thereof in the manufacture of a medicament for use in the production of a vascular damaging effect in warm-blooded animals such as humans. The present invention further relates to compounds of the formula (I), pharmaceutical compositions containing them, processes for their preparation and to a method of treatment using the compounds to produce a vascular damaging effect in a warm- blooded animal such as a human. The compounds of formula (I) and the pharmaceutically acceptable salts thereof may be useful in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent NZ-516641-A (NZ)
Title: Method for RNase- and organic solvent-free plasmid DNA purification using tangential flow filtration
Inventor: BUTLER MICHELLE D
IPC: C12N15/10
Filed: 2000-07-21
Abstract: A process for purifying plasmid DNA from prokaryotic cells comprising: (a) digesting  the cells; (b) incubating the cells in the presence of alkali and a detergent for about 4 to 24 hours, to effect lysis and solubilisation thereof; (c) removing lysate contaminants from the cells to provide a plasmid DNA solution; (d) filtering the solution through a tangential flow filtration device to obtain a retentate containing the plasmid DNA; and (e) collecting the retentate whereby enzymes are not used in any of the above steps to digest RNA.
Patent NZ-518754-A (NZ)
Title: Combination of N-phenyl-N'-benzoyl urea derivative and nectin compounds for parasite control
Inventor: BOUVIER JACQUES
IPC: A01N47/34
Filed: 2000-11-23
Abstract: A composition for the control of ectoparasites and endoparasites on productive livestock, domestic animals and pets comprises: 1-[4-chloro-3-(3-chloro-5-trifluoromethyl-2- pyridyloxy)phenyl]-3-(2,6-difluorobenzoyl)urea and a compound of formula (I) wherein R1 to R4 are as defined in the specification selected from ivermectin, doramectin, moxidectin and selamectin.
Patent NZ-519784-A (NZ)
Title: Remedies for external use for allergic skin diseases not induced by histamine comprising asprin ( acetylsalicylic acid )
Inventor: INAMOTO YUKIKO
IPC: A61P17/00
Filed: 2000-12-15
Abstract: External preparations for allergic dermatitis containing Aspirin ( acetylsalicylic acid ) alone as the active ingredient, are useful for treating allergic dermatitis with lower side effects than alternative treatments; and a method for treating allergic dermatitis by using these agents for external use. Such medicaments may be formulated as an ointment, a tape, a cataplasm, an aerosol or an external powder, and may contain one or more non-toxic carriers. The allergic dermatitis may be a type I or type IV allergy, and may be selected from atopic dermatitis, eczema, contact dermatitis, seborrheic dermatitis, perioral dermatitis, lichen Vidal, nummular eczema, house-wife-eczema and phototoxic dermatitis.
Patent NZ-524580-A (NZ)
Title: Process for preparation of N-1 protected N ring nitrogen containing cyclic polyamines and products thereof
Inventor: GIANDOMENICO CHRISTEN M
IPC: C07D255/02
Filed: 2001-09-28
Abstract: Disclosed herein are cyclic polyamines containing N nitrogens on the ring protected with high yields in a N-1 manner, e.g. all protected but one amino group, by using certain fluoro-containing agents that offer easy deprotection. A process involving selective protection of identical amino groups in cyclic polyamines for preparing N-1 protected N ring nitrogen containing cyclic polyamines such as 1,1'-[1,4-phenylenebis (methylene)]-bis1,4,8,11-tetraazacyclotetradecane is also disclosed.
Patent NZ-525335-A (NZ)
Title: Fan type chemical diffusing apparatus
Inventor: YAMAMOTO KAZUNORI
IPC: A01M29/12
Filed: 2001-09-21
Abstract: A fan type chemical diffusing apparatus is disclosed which enables an apparatus main body, a chemical receptacle and a power supply housing to be made independent in volume from each other and which makes it possible to readily establish an amount of retention of a chemical relative to a rate of airflow produced by a fan, and a length of time period for its service. Disclosed also is a chemical receptacle that prevents chemical impregnated carrier particles from being seized in a space between the end face of the receptacle main body and a lid body, as well as a clip type fastener by which the apparatus can be fastened firmly to an object regardless of its thickness. The fan type chemical diffusing apparatus includes the apparatus main body made of a fan that produces an air flow, a motor for driving the fan and an airflow opening through which the airflow produced by the fan passes; the chemical receptacle for accommodating a chemical impregnated body therein that is impregnated with a chemical, the chemical receptacle having vent holes; and a power supply housing for receiving a power supply therein, the power supply powering the motor, wherein the chemical receptacle and the power supply housing are adapted to be detachably loaded in the apparatus main body and when loaded are each positioned therein so as to receive essentially no limitation in volume from the other. The chemical receptacle for use with a fan type chemical diffusing apparatus for volatilizing and diffusing a chemical in a chemical impregnated body accommodated in the chemical receptacle by means of an airflow produced by a fan, comprises: a cylindrical receptacle main body having its cylindrical wall closed with its one end wall formed with a large number of vent holes; and a cylindrical lid body having its cylindrical wall closed with its one end wall formed with a large number of vent holes, wherein the cylindrical wall of the lid body is adapted to be fitted into and with an inner surface of the cylindrical wall of the receptacle main body. The clip type fastener for the fan type chemical diffusing apparatus, includes a clip member in the form of a tongue attached to an outer wall of the fan type chemical diffusing apparatus wherein the clip having a pressure foot portion is adapted to be so hung on an object such as an apparel of the user that the object is inserted and gripped between the external wall of the fan type chemical diffusing apparatus and the pressure foot portion, thereby fastening the fan type chemical diffusing apparatus to the object, and has the feature that the clip member comprises a plurality of clip pressure foot portions disposed mutually spaced apart in a direction perpendicular to that in which the object is inserted as aforesaid; and one or more raised portions so formed on the said outer wall as to come into between adjacent such pressure foot portions.
Patent NZ-526131-A (NZ)
Inventor: CALDWELL MELISSA CLAIRE
Filed: 2000-10-05
Abstract: A cutting device 10 has an open channel end with inwardly facing cutting edges on at least the sides and base of the channel.
Patent NZ-526918-A (NZ)
Title: Quinazoline derivatives, medicaments containing said compounds, their utilization and method for the production thereof
Inventor: HIMMELSBACH FRANK
IPC: A61P11/00
Filed: 2001-12-12
Abstract: Quinazoline derivatives of formula (I) and the production thereof, wherein Ra, Rb and Rc are as defined in the specification, their tautomers, their stereoisomers and their salts, especially their physiologically acceptable salts with inorganic or organic acids are disclosed. These compounds have valuable pharmacological properties, especially an inhibiting effect upon signal transduction caused by tyrosine kinase, which makes them suitable for use in the treatment of diseases, especially of tumoral diseases, diseases of the lung and the respiratory tract.
Patent NZ-527833-A (NZ)
Title: Application of powder paint using dielectric brush to charge powder, and rotating screen
Inventor: BLADE DARREN JOHN
IPC: B05D1/28
Filed: 2003-08-26
Abstract: Brush 7 of dielectric material electrostatically charges powder 10. Rotating perforated drum screen 6 is electrically conductive and not earthed and is positioned above the substrate to be coated. Typically the substrate is then passed through oven 8.
Patent NZ-529079-A (NZ)
Title: A shower or bath wall panel and method of forming same
Inventor: HATRICK-SMITH JOHN
IPC: A47K3/28
Filed: 2003-10-22
Abstract: A shower or bath wall liner panel (1) includes panel sections on either side of a fold (4) down the panel, and opposing non-planar formations (7) and (8) integrally formed in the panel on either side of the fold from which after installation of the liner panel one or more of a shelf, soap dish, flannel rail, or a step (10) may be supported within a shower enclosure or above a bath, or which form integrally one or more of a shelf or basket, soap dish, flannel rail, or step.
Patent NZ-530451-A (NZ)
Title: TIM gene sequences and their use in immunological disorders and cancer
Inventor: MCINTIRE JENNIFER JONES
IPC: A61K39/395
Filed: 2002-07-01
Abstract: An isolated nucleic acid molecule comprises a mammalian TIM-1 gene sequence other than rat TIM-1 gene sequence and in the case where the mammalian TIM-1 gene sequence is a human TIM-1 sequence, the gene sequence varies from wild-type as set forth for any one of the alleles shown in Figure 8. Also described is an array of oligonucleotides comprising two or more probes for the detection of a TIM-1 gene polymorphism, and a transgenic mouse for TIM-1 gene function comprising a knockout of TIM-1 gene.
Patent NZ-537689-A (NZ)
Title: A self-latching magnetic latching device
Inventor: CLARK ANTHONY JOHN
IPC: E05C19/16
Filed: 2005-01-14
Abstract: A self-latching device for latching, in a predetermined position, two members which are otherwise moveable relative to one another, the device comprising: a housing, a latch arm displaceably mounted in the housing for mounting the latch arm on a first of the two members, the latch arm being displaceable along a path through the housing and having a latch portion mounted to extend from the housing when in a latching position, a retaining element adapted to be mounted on the second of the two members and providing a latching shoulder for the latch position to prevent relative movement of the members from the predetermined position. At least one of the latch arm and the retaining element providing a magnetic field and the other having magnetic properties arranged to cause latching engagement of the latch arm with the latching shoulder under the influence of the magnetic field when the members are in the predetermined position, whereby relative movement of the two members is substantially prevented but the latch portion is displaceable under applied force away from the retaining element to a retracted position so that the members may be moved apart. A resilient biasing means associated with the latch arm to bias it towards the retracted position, but with a biasing force on the latch arm which is less than the force imparted on the latch arm by the magnetic field when the members are located in the predetermined position. An actuator mounted on the housing and extending transversely to the path of displacement of the latch portion for receiving a displacement force to displace the latch arm from its latching position to its retracted position, whereby the two members may be moved apart away from the predetermined position. A connector for connecting the actuator and the latch arm to displace the latch arm from its latching position to its retracted position and to leave the actuator free to move relative to the connector, resilient restoring means for returning the actuator to its initial position on removal of the displacement force leaving the biasing means to maintain the latch arm substantially in its retracted position, whereby when in the predetermined position the latch arm is displaceable under the magnetic forces against the biasing means to re-establish its latching position.
Patent NZ-539463-A (NZ)
Title: A shoe
Inventor: BROADLEY CHERIE PETREA
Filed: 2005-04-15
Abstract: A shoe provides a sole under the ball of the foot but none below the arch or heel. An upper encircles the matatarsal bones and the distal end of the tarsals. An inelastic ankle band shaped as a "c" holds the shoe on the foot. Support is mainly longitudinal, includes over the arch, may be adjustable and is provided without causing foot distortion. Sensation from exposed parts of the foot promotes kinaesthetic procedures for teaching and learning dance. Variations enclose the dorsal part of the foot, some enclose the toes, and one option is a toe box for en pointe.
Patent NZ-544198-A (NZ)
Title: Method and apparatus for collection of fluids
Inventor: RAWLIN GRANT THOMAS
IPC: A01J5/04
Filed: 2004-06-10
Abstract: An apparatus for use with a milking machine comprising one or more teat cups and a vacuum source providing a pulsed vacuum in the teat cups, for collecting a small volume of liquid for cold storage, the apparatus comprising: (a) a fluid collection receptacle (15) in the form of a flexible bag having a collar and an opening (17), (b) a housing for the flexible bag comprising an inlet conduit (12) extending into the housing for receiving the liquid from one or more teat cups, an opening within the housing for delivering the liquid and a port for providing a vacuum within the housing from the vacuum source, (c) means for retaining (14) the collar (16) of the flexible bag about the inlet conduit so that the bag receives liquid from the inlet opening, and (d) means for transfer of the vacuum from the port to the inlet conduit. A milking system incorporating the apparatus is also claimed.
Patent NZ-545153-A (NZ)
Title: Drum applicator for liquids onto growing plants
Inventor: HAZENVELD MARTIN
IPC: A01M21/04
Filed: 2004-07-02
Abstract: An apparatus for applying liquids onto plants growing in the ground includes a frame supporting a drum. The frame is adapted for displacement relative to a ground surface (3) having plant matter (4,5,6) and the drum is rotatably disposed relative to the frame at a rest position (H2) having a height above said ground surface which allows for engagement of an outer circumferential surface (9) of the drum with at least some of said plant matter (4,5). An applicator applies liquid onto the circumferential surface of the drum such that the liquid is transferable to at least some of the plant matter as the frame is displaced relative to said ground surface. The drum is retractably mounted to the frame such that the drum retracts from the rest position upon engagement with a ground obstacle (17) and returns to the rest position subsequent to engagement with the ground obstacle.
Patent NZ-545530-A (NZ)
Title: Shrink lock washer
Inventor: CANCIAN DANNY
Filed: 2006-02-24
Abstract: This discloses a shrink lock washer for preventing and/or lessening the effect of timber shrinkage or movements occurring in buildings or like structures. The shrink lock washer has an upper washer portion 1 adapted to be attached to a fastener for fastening timber to another piece of timber and/or to a structural member. A lower washer portion 5 of the shrink lock washer is adapted to be positioned beneath and movable relative to the upper washer portion 1. A base plate which is positioned between the lower washer portion and the timber is adapted to prevent the lower portion moving away from the upper portion. A biasing portion 8 is connected to the lower washer portion and fixable to the timber. In use the biasing action of the biasing portion 8 causes the shrink lock washer to compensate for timber shrinkage or other movement of the timber.
Patent NZ-546054-A (NZ)
Title: Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
Inventor: CHEN ROGER SHEN-CHU
IPC: A61K31/454
Filed: 2004-09-03
Abstract: Disclosed are eight different polymorphs of 3-(4-amino-1-oxo-1,3 dihydroisoindol-2-yl)-piperidine-2,6-dione, and their use in treating cancer, a myelodysplastic syndrome, or a myeloproliferative disease.
Patent NZ-546912-A (NZ)
Title: Use of C-peptides in manufacture of a medicament in once daily dose for treating diabetes and microvascular complications
Inventor: EKBERG KARIN
IPC: A61K38/28
Filed: 2004-10-13
Abstract: Disclosed is the use of a C-peptide in the manufacture of a medicament for administration to a patient as a once daily for the treatment of diabetes and/or microvascular diabetic complications, wherein said once daily dose does not include a continuous administration or the presence of release rate-controlling agents.
Patent NZ-556263-A (NZ)
Title: Spray dried compositions
Inventor: BARNWELL STEPHEN GEORGE
IPC: A23L27/00
Filed: 2005-12-20
Abstract: Disclosed is a method comprising the steps of: i) providing an emulsion of: a) an aqueous solvent, b) a carrier material dispersible or soluble in (a) , said carrier material being solid at ambient temperature, c) a volatile second liquid phase which is not miscible with (a), d) a material which is dispersible or soluble in (c) but not in (a), and, drying the emulsion above ambient temperature to simultaneously remove (a) and (c) and thereby obtain the material (b) in solid form with (d) dispersed therein, said dispersion of (d) being a nano-scale dispersion, having a maximum particle size of 615nm.
Patent NZ-556630-A (NZ)
Title: Extended release formulation of levetiracetam including a hydrophilic rate controlling polymer
Inventor: KSHIRSAGAR RAJESH
IPC: A61K9/30
Filed: 2005-08-12
Abstract: Disclosed is an extended release tablet of levetiracetam comprising about 30-85% w/w of levetiracetam and about 1-50% w/w of at least one hydrophilic rate controlling polymer and which provides a peak blood plasma level of levetiracetam between about 12 and about 13 hours after administration. Specific formulations which achieve this result are described in the specification.