baber/WOPTO huggingface dataset:
Patent JP-3958352-B2 (JP)
IPC: A61K47/36
Filed: 1993-02-04
Granted: 2007-08-15
Abstract: PCT No. PCT/GB93/00228 Sec. 371 Date Jul. 12, 1994 Sec. 102(e) Date Jul. 12, 1994 PCT Filed Feb. 4, 1993 PCT Pub. No. WO93/15737 PCT Pub. Date Aug. 19, 1993A composition for nasal administration of polar metabolites of opioid analgesics comprises a polar metabolite of an opioid analgesic and an absorption promoting agent. Preferred metabolites morphine-6-glucuronide and morphine-6-sulphate. A preferred absorption promoting agent is chitosan but other suitable agents include cationic polymers, bioadhesive agents, surface active agents, fatty acids, chelating agents, mucolytic agents, cyclodextrin, microsphere preparations or combinations thereof.
Patent JP-3029460-B2 (JP)
IPC: C07D311/94
Filed: 1995-11-03
Granted: 2000-04-04
Abstract: Described are novel photochromic indeno-fused naphthopyran compounds, examples of which are naphthopyran compounds having a substituted or unsubstituted indeno group, the 2,1 positions of which are fused to the f side of the naphtho portion of the naphthopyran, and certain substituents at the 3-position of the pyran ring. Certain substituents may also be present at the number 5, 6, 7, 8, 9, 10, 11, 12, or 13 carbon atoms of the compounds. These compounds may be represented by graphic formula (I). Also described are polymeric organic host materials that contain or that are coated with such compounds. Optically clear articles such as ophthalmic lenses or other plastic transparencies that incorporate the novel naphthopyran compounds or combinations thereof with complementary photochromic compounds, e.g., certain other naphthopyrans, benzopyrans, and spiro(indoline)type compounds, are also described.
Patent JP-4170397-B2 (JP)
IPC: C08K3/00
Filed: 1997-10-23
Granted: 2008-10-22
Abstract: An electrically conductive polyacetal composition having improved toughness and flexibility, as well as good fluidity and processability. The composition includes an oxymethylene polymer, an elastomeric polyurethane, and an electrically conductive carbon black having a lower structure level (DBP absorption) and larger particle size (lower surface area) than conductive carbon blacks heretofore used in these compositions. The composition includes between about 65 and about 85 percent, by weight, of the oxymethylene polymer, between about 10 and about 20 percent, by weight, of the electrically conductive carbon black, and between about 10 and about 20 percent, by weight, of the elastomeric polyurethane. The electrically conductive carbon black has a surface area BET (N2) of between about 40 and about 100 m2/g, and a pore volume, DBP absorption, of between about 150 and about 350 ml/100g. The electrically conductive carbon black used in the present compositions is more easily dispersed in the composition polymers and lessens any increase in melt viscosity during compounding.
Patent JP-3130048-B2 (JP)
IPC: A61K38/09
Filed: 1995-02-02
Granted: 2001-01-31
Abstract: A method of treating an ovarian estrogen dependent condition such as endometriosis, uterine leiomyomata, PMS or DUB involving the administration of gonadotropin releasing hormone analog and the administration of antiprogestin, which will provide a therapeutic method for long term treatment without rapid loss of bone density, as occurs using GnRH analogs alone.
Patent JP-3734265-B2 (JP)
IPC: A61F13/56
Filed: 1995-02-16
Granted: 2006-01-11
Abstract: The present invention provides a three-dimensional, macroscopically expanded, apertured, laminate web suitable for use as a topsheet on an absorbent article and a method for making the same. The web includes a first layer of substantially transparent, polymeric material having an inner surface and an outer surface. A nonwoven web is secured to the inner surface of the substantially transparent polymeric material and is visible through the substantially transparent polymeric material. The presence of the nonwoven web creates the appearance of a fibrous web which is perceived as soft and skin friendly while still maintaining the fluid transport benefits of prior art plastic webs.
Patent JP-4671372-B2 (JP)
IPC: C07K14/475
Filed: 1997-11-14
Granted: 2011-04-13
Abstract: Methods are provided for large scale purification of neurotrophins, including mature NGF, suitable for clinical use. The methods provide means to separate neurotrophins from various less desirable misprocessed, misfolded, size, glycosylated, or charge forms. Compositions of neurotrophins, including mature NGF, substantially free of these variants are also provided.
Patent JP-2925746-B2 (JP)
IPC: C07C5/08
Filed: 1996-12-12
Granted: 1999-07-28
Abstract: A process for isomerizing 2-alkyl-3-monoalkenenitrile to form linear nitriles employing a catalyst comprising the combination of a zero valent nickel compound and certain bidentate phosphorus compounds.
Patent JP-3328287-B2 (JP)
IPC: B01D21/00
Filed: 1994-05-09
Granted: 2002-09-24
Abstract: PCT No. PCT/GB94/00997 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed May 9, 1994 PCT Pub. No. WO94/26384 PCT Pub. Date Nov. 24, 1994Disclosed is a device for separating particles from a bulk liquid, such as viable hybridoma cells from antibody-containing liquid medium. The device comprises a plurality of settlement plates, or other surfaces, being inclined to the vertical, and a pump or other means for causing liquid containing the particles to flow upwardly over the surfaces at such a rate as to allow particles to be separated from the bulk liquid to form sediment layers on the surfaces and slide down them for collection at an appropriate point.
Patent JP-3621111-B2 (JP)
IPC: A61B17/16
Filed: 1996-02-26
Granted: 2005-02-16
Abstract: A guarded sleeve system for use in human spinal surgery across the height of a disc space between two adjacent vertebral bodies, comprising: an outer sleeve having an opening for providing protected access to the disc space and at least portions of the adjacent vertebral bodies; and 
at least one extended portion extending from the outer sleeve for insertion into the disc space between the adjacent vertebral bodies, said at least one extended portion having a portion for bearing against each of the adjacent endplates of the adjacent vertebral bodies, said portion of said at least one extended portion having upper and lower surfaces adapted to contact the respective endplates of the adjacent vertebral bodies for properly aligning and distancing apart the adjacent vertebral bodies.
Patent JP-4071292-B2 (JP)
IPC: H04B1/59
Filed: 1998-01-19
Granted: 2008-04-02
Abstract: In a transponder communication device (1) having a selector for the successive individual selection of transponders (2) the selector having interrogator (5) for generating at least one item of interrogation information (AFI) with which the transponders (2) can be interrogated to transmit answer information (AWI) in response to the interrogation information (AFI), and time-window generator (17) for generating a series of K successive time windows (ZF) and controller (20) for the time-window generator (17), which controller can activate the time-window generator (17) so as to generate the series F of K time windows (ZF) a number of times in succession, and evaluator (22) which cooperates with the time-window generator (17) and by which, depending on the occurrence of at least one item of answer information (AWI) transmitted to the transponder communication device (1) by a transponder (2) in response to interrogation information (AFI), a transponder (2) can be selected in at least one time window (ZF) in each series (F) of the series (F) of K time windows (ZF) generated a number of times in succession.
Patent JP-4446023-B2 (JP)
IPC: A61P25/00
Filed: 1998-02-13
Granted: 2010-04-07
Abstract: Compounds of the general structural formula <CHEM> are shown to have AMPA receptor enhancing properties. The compounds are useful for such therapeutic purposes as facilitating the learning of behaviors dependent upon AMPA receptors, and in treating conditions, such as memory impairment, in which AMPA receptors, or synapses utilizing these receptors, are reduced in numbers or efficiency. They may also be used to enhance excitatory synaptic activity in order to restore an imbalance between brain subregions, as in treatment of schizophrenia or schizophreniform behavior. <IMAGE>
Patent JP-4189035-B2 (JP)
IPC: C12N15/22
Filed: 1998-04-16
Granted: 2008-12-03
Abstract: The invention relates to variants of recombinant human beta interferon and to a method for the production thereof, wherein at least one of the following amino acids Leu(5), Phe(8), Phe(15), Leu(47), Phe(50), Leu(106), Phe(111), Leu(116), Leu(120) and Phe(156) is exchanged with hydrophilic amino acid with a hydroxy group, specially serine, tyrosine or threonine, resulting in enhanced hydrophilic property of the protein surface.
Patent ES-2167255-B2 (ES)
Title: Perfeccionamientos en encofrados para columnas cilindricas.
Inventor: VALERO SALINAS JOSE MANUEL
IPC: E04G13/02
Filed: 2000-07-17
Granted: 2003-11-01
Abstract: Perfeccionamientos en encofrados para columnas cilíndricas. Aplicables a un encofrado a base de un cuerpo tubular de madera plastificada, plástico rígido o similar, debidamente estabilizado mediante una envolvente exterior a base de una malla de fibra de vidrio arrollada helicoidalmente con o sin interposición de un segundo cuerpo tubular de poliestireno expandido, los perfeccionamientos de la invención consisten en obtener un cuerpo tubular interno de plástico o madera a base de una placa única (1), de anchura coincidente con el perímetro del encofrado a obtener, placa (1) de cara interna (2) continua y en cuya cara externa (4) se establece una pluralidad de cortes (3), longitudinales, uniformemente distribuidos, que afectan mayoritariamente en espesor a dicha placa, definiendo zonas debilitadas (5) que permiten una fácil deformación de la citada placa (1), inicialmente plana, para convertirla en un elemento tubular y cilíndrico.
Patent ES-2296452-B2 (ES)
Title: Detector de pedunculos y tallos vegetales basado en la designacion optica con laser de linea.
Inventor: CASAR CORREDERA JOSE RAMON
IPC: A01D46/30
Filed: 2005-06-29
Granted: 2009-12-04
Abstract: Detector de pedúnculos y tallos vegetales basado
en la designación óptica con láser de línea. 
     Esta invención resuelve el problema de designar
y estimar con precisión la posición 3-D de un punto
de un pedúnculo o  de un tallo mediante la utilización de un diodo
láser de línea para generar instantáneamente sobre él una marca
óptica  perfectamente identificable. Un láser de línea es un diodo
láser de "spot" convencional con una lente que esparce la luz 
en ángulo piano o abanico que, al alcanzar el pedúnculo (o tallo),
produce sobre él una marca óptica. A partir de la  Imagen o Imágenes
de la escena tomadas por el sensor o sensores de visión, se puede
encontrar la posición 3-D del  punto marcado por un
proceso convencional de triangulación, y, en consecuencia, dirigir
con precisión un manipulador  robótico para realizar la tarea
deseada: recolección, trasplante, etc.
Patent ES-2631183-B2 (ES)
Title: Conector dual y enchufe de pared dual aptos para su conexión a redes eléctricas y redes domésticas de comunicaciones de fibra óptica
Inventor: SAN JUAN CAMBRA ANTONIO
IPC: H02G3/08
Filed: 2016-02-26
Granted: 2017-12-04
Abstract: Conector dual y enchufe de pared dual aptos para su conexión a redes eléctricas y redes domésticas de comunicaciones de fibra óptica.#La invención se refiere a un conector dual (1) apto para su conexión a una red eléctrica y una red empotrada doméstica de comunicaciones de fibra óptica que comprende: una carcasa (2) equipada con un primer alojamiento (3) apto para recibir un embellecedor frontal (4) de un enchufe de pared, conectable a la red eléctrica; y al menos un segundo alojamiento (5) apto para recibir uno o más módulos de conexión eléctrica (6) a una red de datos; uno o más módulos de conexión de fibra óptica (7) entre la red doméstica de comunicaciones de fibra óptica y el conector dual (1); y un dispositivo convertidor de medios (8) integrado en la carcasa (2), apto para la conversión bidireccional de datos entre la red doméstica de comunicaciones de fibra óptica y los equipos electrónicos domésticos. La invención se refiere, asimismo, a un enchufe de pared que comprende el citado conector (1).
Patent AU-2001275489-B2 (AU)
Title: Liposomal encapsulation of chelated actinium-225 and uses thereof
Inventor: MCDEVITT MICHAEL R
IPC: A61M36/12
Filed: 2001-06-15
Granted: 2005-01-27
Abstract: The present invention provides targeted delivery of alpha particle-emitting radionuclides and their alpha-emitting progeny using liposomal encapsulation to prevent the loss of daughter radionuclides from the targeting vehicle and, therefore, from the tumor site.
Patent AU-2002257680-B2 (AU)
Title: Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain
Inventor: SELVE NORMA
IPC: A61P23/00
Filed: 2002-03-19
Granted: 2006-12-14
Abstract: The present invention concerns the use of peptidic compounds for the preparation of a pharmaceutical composition for the treatment of diabetic neuropathic pain.
Patent AU-2003213660-B2 (AU)
Title: Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted benzylsulfones for treating proliferative disorders
Inventor: REDDY RAMANA M V
IPC: A61K31/19
Filed: 2003-02-28
Granted: 2010-04-22
Abstract: Methods of treating cancer using compounds according to Formula (I) are disclosed herein, wherein X, X1, X2, Ra, R1, R2, R3, R4, R5, R6, R7, g, M, y, a, b, d, e, V, W, Z and Q are as defined herein.
Patent AU-2003264607-B2 (AU)
Title: Centrifuge Blade Design
Inventor: BEATTEY JEFFERY N
IPC: B04B11/04
Filed: 2003-11-28
Granted: 2004-05-13
Abstract: An improved blade design and method for enhancing the efficiency of operation of a centrifuge is disclosed based on measuring a varying value of the load on the centrifuge as the flow of contaminated fluid is injected into the centrifuge. The centrifuge has a plurality of blades with radially overlapping edges to keep the fluid being centrifuged compartmentalized and thus quiet for maximum efficiency. Additionally, the scraping blade assembly has blades which are angled in the scraping direction to force the solids towards the exit of the centrifuge, whether that be at the bottom or the top. A programmable logic controller monitors the load on the drive motor and compares a baseline value of load after accelerating the rotor to speed to the value of load while the contaminated fluid is injected into the rotor. The varying second value of load, measured during injection of fluid into the assembly, is compared to the baseline value of load to determine flow rate of the fluid being injected into the rotor assembly or to ascertain whether any dysfunction is occurring and to take appropriate steps to correct malfunction.
Patent AU-2003277189-B2 (AU)
Title: Trailer mounted bursting energy absorbtion system
Inventor: SICKING DEAN L
IPC: F16F7/12
Filed: 2003-10-01
Granted: 2008-12-11
Abstract: A portable crash attenuation system having a trailer frame and an energy absorption mechanism attached thereto. The absorption mechanism has a first stage pivotably connected to a second stage and the second stage is pivotably connected to the frame. By pivoting the stages about hinges the attenuation system may be folded from an extended, deployed position or mode to a shortened transit mode for easy relocation of the entire attenuation system.
Patent AU-2003280214-B2 (AU)
Title: Stacked heater elements in a thermal ink jet printhead
Inventor: SILVERBROOK KIA
IPC: B41J2/05
Filed: 2003-11-17
Granted: 2006-10-05
Abstract: A pagewidth printhead includes a printhead controller; a wafer substrate defining a plurality of inlets; and a plurality of micro-electromechanical nozzle arrangements on the wafer substrate and under control of the controller. Each nozzle arrangement includes side walls disposed on the wafer substrate with a roof portion attached to said side walls to define a printing fluid chamber in fluid communication with one inlet, the roof portion defining an ejection port; and at least two heater elements suspended between the side walls in the fluid chamber for forming a vapour bubble in response to electrical actuation energy being applied thereto, whereby a pressure increase in the chamber is effected and fluid in the fluid chamber ejected therefrom via the ejection port. The controller is configured to actuate the at least two heater elements individually to facilitate ejection of weighted ink drop volumes from the nozzle arrangement. A size of a first of the at least two heater elements is different to a size of a second of the at least two heater elements.
Patent AU-2004233705-B2 (AU)
Title: Preventives or remedies for hepatopathy
Inventor: HOSODA HIROSHI
IPC: A61K38/00
Filed: 2004-04-30
Granted: 2009-09-17
Abstract: The present invention relates to a preventive or a therapeutic agent for hepatopathy, comprising, as an effective ingredient, a polypeptide derivative having an activity of binding to growth hormone secretagogue receptor and thus elevating intracellular calcium ion concentration, and having one amino acid sequence selected from the group consisting of amino acid sequences represented by SEQ ID NOS: 1 to 22, or an amino acid sequence in which one to several amino acids are deleted, substituted or added at the amino acid residues other that the first to forth amino acid residues from the amino-terminus in the said amino acid sequence, or a pharmacologically acceptable salt thereof. The preventive or the therapeutic agent for hepatopathy in accordance with the present invention is useful as a drug suitable for treating or preventing hepatic diseases such as hepatitis, liver cirrhosis and hepatic insufficiency. Further, the preventive or the therapeutic agent for hepatopathy in accordance with the present invention is also useful as an agent of promoting hepatic regeneration and hepatic function recovery after hepatectomy.
Patent AU-2004238515-B2 (AU)
Title: Diaminopyrroloquinazolines compounds as protein tyrosine phosphatase inhibitors
Inventor: THAKKAR KSHITIJ CHHABILBHAI
IPC: C07D487/04
Filed: 2004-05-10
Granted: 2008-01-24
Abstract: This invention relates to diaminopyrroloquinazoline compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals.
Patent AU-2004255515-B2 (AU)
Title: Pharmaceutical formulations for intranasal administration of protein comprising a chitosan or a derivative thereof
Inventor: SMITH ALAN
IPC: A61K9/00
Filed: 2004-07-02
Granted: 2009-04-30
Abstract: There is provided a powder formulation for nasal delivery including a protein having a molecular weight of 10 kDa or greater and chitosan or a derivative thereof or a salt of chitosan or a salt of a derivative of chitosan. Preferably the protein is human growth hormone.
Patent AU-2004290494-B2 (AU)
Title: New formulation for retinoid-containing soft gelatin capsules
Inventor: GABRIEL BERNHARD
IPC: A61K31/07
Filed: 2004-10-28
Granted: 2008-06-19
Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.
Patent AU-2005238942-B2 (AU)
Title: Reducing viscosity of oil for production from a hydrocarbon containing formation
Inventor: PASTOR-SANZ GUILLERMO
IPC: H05B3/10
Filed: 2005-04-22
Granted: 2008-09-04
Abstract: Certain embodiments provide a heater. A heater device includes a skin effect component having at least one insulated electrical core conductor in electrical communication with an adjacent and substantially parallel, elongated ferromagnetic shape having a reduction and localization of the depth and width of the effective conductor path in the cross-section of the ferromagnetic wall; and, an inorganic ceramic insulation component.
Patent AU-2005269663-B2 (AU)
Title: Stent with an end member having a lateral extension
Inventor: PARKER FRED T
IPC: A61F2/06
Filed: 2005-07-22
Granted: 2010-09-23
Abstract: A marker and pushing member are provided with lateral extensions connected to a connecting portion. The connecting portion connects the marker/pushing member to a proximal or distal end of the stent. The lateral extensions distribute forces applied to the marker/pushing member so that part of the force is applied to the connecting member and part of the force is applied to a portion of the stent structure that is not directly connected to the connecting member.
Patent AU-2006235742-B2 (AU)
Title: Conjugate comprising P21 protein for the treatment of cancer
Inventor: CHRISTINA KOUSPAROU
IPC: A61K33/243
Filed: 2006-04-18
Granted: 2011-07-14
Abstract: The P21 protein is used as a medicament in the treatment of cancer. A conjugate comprises a first region comprising the P21 protein, or a homologue or functional fragment thereof; and a second region comprising a translocation factor.
Patent AU-2006239557-B2 (AU)
Title: Novel specific caspase-10 inhibitors
Inventor: CATHERINE VIDAL
IPC: C07C311/17
Filed: 2006-04-06
Granted: 2011-11-03
Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
Patent AU-2006277568-B2 (AU)
Title: Expression vector and methods of producing high levels of proteins
Inventor: ASHISH GOEL
IPC: C07K14/505
Filed: 2006-06-19
Granted: 2011-06-30
Abstract: A process for high expression of protein of interest using an expression vector. The process comprises at least the following regulatory elements: a) a CMV promoter, or its functional variants, b) an intron, c) TPL or its functional variants, d) VA genes or functional variants, and e) a bovine growth hormone polyadenylation sequence or functional variants.
Patent AU-2006290550-B2 (AU)
Title: Mass labels
Inventor: SCHAEFER JUERGEN
IPC: G01N33/68
Filed: 2006-09-11
Granted: 2012-03-29
Abstract: Provided is a set of mass labels, each mass label in the set comprising a mass marker moiety attached via a cleavable linker to a mass normalisation moiety, each mass label in the set having a common mass; wherein the set comprises a plurality of groups of mass labels, the mass of the mass marker moiety being the same for mass labels within a group, the mass of the mass marker moiety being different between groups; the mass marker moiety is capable of fragmentation into two or more fragments; and the mass of at least one fragment of the mass marker moiety differs between mass labels within a group.
Patent AU-2006292598-B2 (AU)
Title: Cyclopropyl amines as modulators of the histamine H3 receptor
Inventor: ALLISON BRETT D
IPC: C07D265/30
Filed: 2006-09-14
Granted: 2012-06-21
Abstract: Certain cyclopropyl amines are histamine H modulators useful in the treatment of histamine H receptor mediated diseases.
Patent AU-2006333047-B2 (AU)
Title: Systems for closing a vessel wound
Inventor: SZABO DAVID
IPC: A61B17/00
Filed: 2006-12-14
Granted: 2012-12-20
Abstract: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from interventional procedures. The vessel wound closure system generally comprises an introducer (10) and a hydratable hemostatic membrane (30) dislodgable from over a portion of the introducer to seal a vessel wound upon hydration of the membrane. The membrane may include a glaze on an outside surface thereof to help contorl hydration of the membrane.