baber/WOPTO huggingface dataset:
Patent CA-2446260-C (CA)
Title: Novel expression vectors and uses thereof
Inventor: KROHN KAI
IPC: C12N15/09
Filed: 2002-05-03
Granted: 2011-06-14
Abstract: The present invention relates to novel vectors, to DNA vaccines and gene therapeutics containing said vectors, to methods for the preparation of the vectors and DNA vaccines and gene therapeutics containing the vectors, and to therapeutic uses of said vectors. More specifically, the present invention relates to novel vectors comprising (a) an expression cassette of a gene of a nuclear-anchoring protein, which contains (i) a DNA binding domain capable of binding to a specific DNA sequence and (ii) a functional domain capable of binding to a nuclear component and (b) a multimerized DNA sequence forming a binding site for the anchoring protein, and optionally (c) one or more expression cassettes of a DNA sequence of interest. In particular the invention relates to vectors that lack a papilloma virus origin of replication. The nuclear-anchoring protein might be the E2 protein of Bovine Papilloma Virus type 1 or Epstein-Barr Virus Nuclear Antigen 1. The invention also relates to vectors that lack an origin of replication functional in a mammalian cell. The invention further relates to methods for expressing a DNA sequence of interest in a subject.
Patent CA-2446374-C (CA)
Title: Surgical wound closure system
Inventor: LUTHRA AJAY K
IPC: A61B17/00
Filed: 2002-05-09
Granted: 2012-09-11
Abstract: A wound closure system and methods utilizes a patient's own blood. The system preferably includes a chamber with a needle and a plunger for transferring and storing blood prior to surgery and the use of reversible anticoagulants. The chamber is pre-loaded with a reversible anticoagulant to prevent the blood from clotting during storage. When the surgery is complete, a counteracting agent is mixed with the withdrawn blood to counteract the reversible anticoagulant and allow the blood to clot. The clottable blood is then reintrduced into the patient to close a wound.
Patent CA-2447552-C (CA)
Inventor: SINGH AMARDEEP
IPC: E21B10/56
Filed: 2003-10-31
Granted: 2007-08-14
Abstract: A cutter element is disclosed having a rounded apex offset from the center line of the insert and having a relatively broad and blunt front face and a narrower, more rounded rear face. The cutter element may be disposed in the outermost inner row of a rolling cone cutter of a bit with the broader front face facing the borehole side wall so as to resist off center wear and resultant bit whirl. When placed in inner rows and oriented with the broader and flatter front face being the first portion of the cutting surface to engage the borehole, enhancements in bit durability may be achieved, particularly when drilling through formations of multiple hardness.
Patent CA-2463061-C (CA)
Title: System and method for reading power meters
Inventor: TUFF MAURICE
IPC: G01D4/00
Filed: 2004-04-01
Granted: 2014-12-09
Abstract: A power meter reader system for automatically reading an indication on a power meter unit having a cyclical property that varies at a rate indicative of power consumption. The system comprises a detection unit that includes a sensor unit for monitoring the cyclical property of the indication and generating a consumption detection signal, a processing unit for generating an information signal based on data related to the consumption detection signal, and a transmitter for transmitting a transmission signal based on the information signal. The processing unit also generates a sensor enable signal to enable the sensor unit for only a portion of the cyclical property of the indication. The system further includes a display unit located remotely with respect to the detection unit for receiving the transmission signal and displaying the power consumption. The detection unit may also employ a prediction model for reducing power consumption in the detection unit.
Patent CA-2467215-C (CA)
Title: Emulsion compositions
Inventor: HOLLIGER PHILIPP
IPC: C12Q1/6844
Filed: 2002-11-18
Granted: 2012-10-02
Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase;  wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
Patent CA-2472558-C (CA)
Inventor: O'DONNELL WILLIAM P
IPC: B61F5/14
Filed: 2003-10-08
Granted: 2010-05-04
Abstract: L'invention concerne un appareil permettant d'absorber l'énergie produite par les voitures de chemin de fer, qui comporte un ensemble ressort doté d'un élément de ressort élastomère disposé en combinaison fonctionnelle avec une structure qui inhibe la détérioration thermique localisée dudit élément de ressort élastomère.
Patent CA-2473629-C (CA)
Title: Improved rotary filing cabinet system and method
Inventor: LODGE REGGIE
IPC: A47B88/00
Filed: 2004-07-13
Granted: 2008-12-09
Abstract: The rotary filing cabinet system and method is provided wherein a short adder cabinet is provided between a tall starter cabinet and a tall adder cabinet. The short adder cabinet includes a tall right front panel assembly of a height which is the same as the height of the tall adder cabinet, and further including first and second covering panels which cover respective side openings above a top paned of the short adder cabinet at a left side of the tall adder cabinet and at a right side of the tall starter cabinet.
Patent CA-2476952-C (CA)
Title: Absorbent article including undergarment fastener adhesive having improved adhesive pattern
Inventor: OHBA KIYOE
IPC: A61F5/44
Filed: 2003-02-21
Granted: 2010-08-17
Abstract: An absorbent article comprises an absorbent core and a backsheet associated with the absorbent core. The backsheet has a garment facing side and a first end edge in the first end region. The absorbent article further comprises adhesive attachment means disposed on the garment facing side of the backsheet for securing the absorbent article to an undergarment. The adhesive attachment means has an adhesive pattern which includes (a) a central adhesive section disposed on or along the longitudinal center line. The central adhesive section has a first end in the first end region. The adhesive pattern further includes (b) a pair of side adhesive sections each disposed transversely outboard of the central adhesive section, respectively. Each of the side adhesive section has a first end in the first end region. The first ends of each side adhesive section extends substantially to the first end edge of the backsheet. The first end of the central adhesive section is at least about 5 mm away from the first end edge of the backsheet such that an adhesive free area is formed between the first end of the central adhesive section and the first end edge of the backsheet.
Patent CA-2483030-C (CA)
Inventor: CAMENZIND HUGO
IPC: C08F2/38
Filed: 2003-04-29
Granted: 2011-03-08
Abstract: L'invention concerne un copolymère séquencé préparé par polymérisation radicalaire par transfert d'atome (ARTP), dans lequel le groupe terminal de la chaîne polymère est modifié structurellement par un additif lubrifiant ou polymère sélectionné dans le groupe comprenant les antioxydants, les désactivateurs de métaux, les additifs anti-usure et extrême-pression et les inhibiteurs de corrosion. L'invention concerne également une composition comprenant ce copolymère séquencé structurellement modifié et une composition d'un produit sujet à la dégradation oxydative, thermique ou à une photodégradation tel qu'un lubrifiant ou un polymère.
Patent CA-2487173-C (CA)
Title: Improved counter weight door
Inventor: TOEWS WALTER
IPC: E06B3/50
Filed: 1997-04-16
Granted: 2008-01-08
Abstract: The present Invention relates to an Improved counter weight door of the type for use at an opening in a wall of a building. The counter weight door includes door panels comprising two or more standard sized overhead door panel sections which are Joined together by a pair of J-shaped channel members. A pair of hinge connectors have be mounted side by side at each side of each door panel and adjacent the joint between adjacent top and bottom edges of adjacent door panels The axle of the guide rail follower has been lengthened to allow it to extend through an elongate tubular member on each of the pair of hinge connectors. This gives each pivot connection additional strength and yet allows standard overhead door hinges to be used. Improved pulley mounts allow the pulleys to be easily arranged and secured above and to the side of the opening in the wall, and lie substantially in the plane of the door. Mounting the pulleys directly on the guide rails helps the installer mount the pulleys such that their axis of rotation lies substantially perpendicular to the plane of the door. This helps ensure smooth operation of the pulleys as the door is opened and closed.
Patent CA-2488352-C (CA)
Title: Slidable room assembly and method of installation
Inventor: FEW JEFFREY P
IPC: B60P3/34
Filed: 2004-11-25
Granted: 2019-05-14
Abstract: A slidable room assembly comprises a vehicle body having an opening formed in an exterior wall, and a reciprocable slideout unit or compartment disposed in the opening and slidable between a retracted position and an extended position. Sliding movement of the slideout unit is controlled by means of a drive mechanism that includes two sets of cabling. The drive mechanism includes a frame installed about the opening in the vehicle body. The frame includes a header, a sill and two pre-assembled jambs. The pre-assembled jambs have a plurality of pulleys with a plurality of cables pre-installed inside the jambs around the pulleys. One end of the cables, attached to the slidable room, is pre-strung through a cable extension hole. The other end of the cables extends out an end of the jamb.
Patent CA-2498034-C (CA)
Title: Flow control system
Inventor: PAUL PHILLIP H
IPC: B01D61/56
Filed: 2003-09-17
Granted: 2012-07-10
Abstract: Method and apparatus for providing liquid flow at a controlled rate less than 100 microliters/minute, and for varying the flow rate in a desired way. A  liquid is driven through a conduit by pressure. The rate of flow of the liquid through the conduit is measured and compared to a desired value. The resulting information is then used to make any desirable changes in the driving pressure. In one embodiment, which is particularly suitable for a mixture of liquids to be supplied to a gradient liquid chromatography column, the rate of flow of each of two or more different liquids is controlled individually, and the liquids are then mixed together.
Patent CA-2500079-C (CA)
Inventor: PANG ZIJING
IPC: F03B11/04
Filed: 2003-09-12
Granted: 2013-06-25
Abstract: La présente invention a trait à un appareil à blocage de couplage élastique constitué par un outil particulier avec un rotor entraîné par couplage élastique, utilisé sur une unité de génération hydroélectrique et le centre de commande axiale d'autres transferts. Les éléments constitutifs sont les suivants : le bâti supérieur du dispositif entraîné est relié à un support élastique qui est lui-même relié à une enveloppe qui est solidarisé à une plaque de couvercle sur laquelle sont montés des mécanismes de réduction et des moteurs électriques en position symétrique de 180 degrés. L'arbre de sortie du mécanisme de réduction s'étend dans l'enveloppe sous la plaque de couvercle, et est relié à une petite roue dentée qui s'engrène avec la grande roue dentée. La grande roue dentée est reliée à un couplage par une clavette parallèle, et le couplage est relié au rotor qui est le dispositif entraîné. L'avantage de l'invention est qu'elle présente une construction plus rationnelle, la concentricité est réglée de manière plus appropriée, et la connexion élastique rend le fonctionnement plus simple et avec moins de vibration, que dans l'état de la technique, et la distorsion provoquée par porte-à-faux est supprimée, et la justesse et la précision de fonctionnement sont accrues grâce à l'engrènement sans à-coups des roues dentées.
Patent CA-2506070-C (CA)
Inventor: JOKINEN REIJO
IPC: D21F5/04
Filed: 2003-11-19
Granted: 2009-11-03
Abstract: La présente invention concerne un mécanisme d'étanchéité (7) contre une toile mobile (4b) dans une machine à papier ou analogue.Le mécanisme d'étanchéité comprend un élément d'étanchéité rigide (9) placé sur le côté de la toile (4b) sur toute la largeur, en lien avec une feuille de papier (4a) supportée par la toile (4b). Le mécanisme d'étanchéité a été agencé sur un support de façon que l'emplacement de l'élément d'étanchéité par rapport à la toile (4b) peut être réglé plus près ou, selon le cas, plus loin de la toile. L'invention comprend, comme élément d'étanchéité, un joint labyrinthe à chambre unique (19).
Patent CA-2506854-C (CA)
Title: Systeme preneur-placeur reparti, dirige par eclairage, intelligent et sans fil
Inventor: PECK JOHN C
IPC: G06Q10/08
Filed: 2004-01-30
Granted: 2015-01-13
Abstract: L'invention concerne un système selon lequel un ordinateur portable situé sur un chariot permet de se déplacer entre des emplacements dans un entrepôt et des adresses d'emplacement éclairées situées sur des baies de stockage dans une installation de stockage, et de communiquer des instructions au moyen d'un double émetteur/récepteur bidirectionnel situé sur le chariot à une unité de commande de préhension positionnée sur chaque baie. Cette unité de commande de préhension se trouvant sur la baie est reliée à des ensembles d'éclairage intelligents situés au niveau de chaque emplacement sur la baie, qui en réponse à des instructions provenant de l'ordinateur portable, s'éclairent de manière à indiquer un besoin et une quantité d'unités de gestion des stocks (SKU) à récupérer depuis l'emplacement éclairé. En outre, l'ordinateur portable communique des instructions au moyen du émetteur/récepteur bidirectionnel à l'intention de l'unité de commande de mise en place positionnée sur le chariot qui à son tour communique ces instructions aux ensembles d'éclairage intelligents adjacents à des réceptacles spécifiques situés sur le chariot. Les ensembles d'éclairage intelligents adjacents aux réceptacles s'éclairent en réponse aux instructions provenant de l'ordinateur portable, qui indiquent la quantité de SKU récupérées destinées à être déposées dans chaque réceptacle, ce qui permet de faciliter la préhension regroupée de commandes multiples par un utilisateur du chariot.
Patent CA-2509579-C (CA)
Title: Systems and methods for detecting a security breach in a computer system
Inventor: YODAIKEN VICTOR J
IPC: H04L9/00
Filed: 2003-12-12
Granted: 2011-10-18
Abstract: The present invention provides systems and methods for applying hard-real-time capabilities in software to software security. For exemple, the systems and methods of the present invention allow a programmer to attach a periodic integrity check to an application so that an attack on the application would need to succeed completely within a narrow and unpredictable time window in order to remain undetected.
Patent CA-2510180-C (CA)
Title: Humanized antibody (h14.18) of the mouse 14.18 antibody binding to gd2 and its fusion with il-2
Inventor: GILLIES STEPHEN D
IPC: A61K48/00
Filed: 2003-12-16
Granted: 2012-09-11
Abstract: The invention provides humanized antibody H14.18 binding the human cell surface glycosphingolipid GD2. The antibody comprises modified variable regions, more specially, modified framework regions, which reduce their immunogenitity when administered to a human. The antibody may be coupled to the therapeutic agent such as IL-2 and used in the treatment of cancer.
Patent CA-2512657-C (CA)
Inventor: KIM YOUNG MIN
IPC: A61K47/42
Filed: 2004-11-13
Granted: 2014-01-07
Abstract: Disclosed are a protein conjugate with improved in vivo duration and stability and the use thereof. The protein conjugate includes a physiologically active polypeptide, a non-peptide polymer and an immunoglobulin Fc fragment. Since the three components are covalently linked, the protein conjugate has extended in vivo duration and enhanced stability for the physiologically active polypeptide. The protein conjugate maintains the in vivo activity at relatively high levels and remarkably increases the serum half-life for the physiologically active polypeptide, with less risk of inducing undesirable immune responses. Thus, the protein conjugate is useful for developing long-acting formulations of various polypeptide drugs.
Patent CA-2515094-C (CA)
Title: Transdermal granisetron
Inventor: ALTENSCHOEPFER PETER
IPC: A61K31/439
Filed: 2004-02-05
Granted: 2008-12-09
Abstract: Adhesive patches for the transdermal administration of granisetron, comprise an acrylic adhesive containing non-acidic nucleophilic moieties which substantially increase flux of granisetron across the skin.
Patent CA-2517277-C (CA)
Title: System and method for generating an orchestrated advertising campaign
Inventor: NORRINGTON TREVOR
IPC: H04L12/16
Filed: 2005-08-26
Granted: 2015-05-26
Abstract: A system and related techniques host and serve selective, orchestrated advertising campaigns and other content to users depending on contributing advertisers' campaign strategies as well as user interests, prior history or experiences. User's may navigate to a Web or other network site which contains or invokes ads or other media or content. When ad or other content is called, a user identifier may be checked, to determine whether the user has subscribed to or had a profile established with the orchestrated ad platform. If the user does have a unique user identifier associated, an ad engine may perform a lookup of the identifier against potential ad campaigns or delivery modes, to deliver a more coherent or orchestrated stream of ads or other media to the user.
Patent CA-2518355-C (CA)
Inventor: ABADIE AUDE
IPC: F01D11/00
Filed: 2005-09-08
Granted: 2013-03-12
Abstract: This invention pertains to a gas turbine engine including at least a compressor layer with an inner ring (15, 15', 115, 115') under variable setting stator blades (11) including axial centering keys (16, 16') of the said inner ring in relation to the said stator blades on the one hand, and at least a sealing element support mounted on the inner ring on the other hand. It is characterised by the fact that the said rings (16, 16') include a transverse groove (16B, 16'B) which works in conjunction with radial ribs (53, 53', 153, 153') arranged transversally to the axis of the engine on the periphery of the support (50, 50', 150, 150') of the sealing element (51, 151).
Patent CA-2518439-C (CA)
Title: Enterprise console
Inventor: HINDAWI DAVID SALIM
IPC: G06F9/445
Filed: 2004-03-24
Granted: 2011-11-22
Abstract: A console (206) for an enterprise suite is disclosed. The enterprise suite addresses the increasingly complex problem of keeping critical systems updated, compatible, and free of security holes. It uses Fixlet technology to identify vulnerable computers on the network and then allows authorized personnel to correct problems across any subset of the network with a few simple mouse-clicks. The enterprise suite helps keep the networked computers updated and properly patched, all from a central console (206) which, along with supporting architectural enhancements, is the subject matter of this document. The invention allows rolling out a security patch in minutes instead of months, thus allowing an administrator to stay ahead of potential hacker attacks. The invention also makes it possible to track the progress of each computer as updates are applied, thus making it simple to gauge the level of compliance across the entire enterprise.
Patent CA-2519138-C (CA)
Title: A backpack for harvesting electrical energy during walking and for minimizing shoulder strain
Inventor: ROME LAWRENCE C
IPC: H02K7/18
Filed: 2004-03-17
Granted: 2012-01-10
Abstract: A suspended-load backpack designed to permit the load to move relative to the backpack frame during walking and running so that the large movements between the load and the frame of the backpack reduce the fluctuations of absolute vertical motion of the load. Because the hip (and thus the pack frame) go up a down a good deal during walking, a large relative movement between the frame and the load reduces the absolute excursion of the load. This movement may be, in turn, transferred to a motor through, for example, a rack and pinion gear, to convert the mechanical movement to electrical energy. The movement may also be converted to electrical energy by using an electroactive polymer (EAP) to connect the suspended load to the frame. Such designs allow the load to move in a controlled fashion to prevent the patient from losing his or her balance as the load moves up and down along the backpack frame. Such movement of thesuspended-load relative to the frame also reduces the forces on the wearer's shoulders while walking or running, thus reducing the likelihood of orthopedic injury.
Patent CA-2519842-C (CA)
Title: Thermal barrier coating material
Inventor: AKIYAMA KATSUNORI
IPC: C23C30/00
Filed: 2004-03-24
Granted: 2010-08-24
Abstract: A thermal barrier coating material, which comprises, as a main component, a composition having an orthorhombic or monoclinic structure (for example, a tabular perovskite structure represented by the empirical formula: A2B2O7) derived from a perovskite structure or a tetragonal layer structure having a c axis/a axis ratio of 3 or more (for example, a K2NiF4 structure a Sr3Ti2O7 structure and a Sr4Ti3O10 structure), a composition represented by the empirical formula: LaTaO4, or a composition having an olivine type structure represented by the empirical formula: M2SiO4 or (MM~)2SiO4 wherein M and M~  are divalent metal elements. The thermal barrier coating material is novel, is free from problems of the phase transition and the like has a melting point higher than the temperature region for use, and has a thermal conductivity less than that of zirconia and a thermal expansion coefficient greater than that of zirconia.
Patent CA-2520252-C (CA)
Title: Percutaneously implantable medical device configured to promote tissue ingrowth
Inventor: PORTER CHRISTOPHER H
IPC: A61M1/00
Filed: 2004-04-09
Granted: 2012-06-19
Abstract: An implantable device including a housing having a stud projecting percutaneously through an incision in the patient's skin. The stud defines a peripheral surface extending longitudinally inwardly from the stud outer end.  The longitudinal peripheral surface is used as a substrate to carry a peripheral fibrous layer which extends longitudinally along the stud from its outer end adjacent to the skin incision to below the patient's epidermal and dermal skin layers for promoting laterally directed soft tissue ingrowth. The housing also defines a lateral shoulder surface oriented substantially perpendicular to the longitudinal peripheral surface. The shoulder surface, when implanted, is located just inwardly from the patient's outer skin surface. The shoulder surface also carries a porous layer conducive to promoting tissue ingrowth. The provision of both lateral and longitudinal porous layers on the device allows tissue ingrowth, i.e., tissue growth into the interstices of both porous layers to form an enhanced infection resistant barrier while also providing improved device anchoring.