baber/WOPTO huggingface dataset:
Patent NZ-521324-A (NZ)
Title: A process for the synthesis of N-[(S)-1-carboxybutyl]- (S)-alanine esters and use in synthesis of perindopril and its salts
Inventor: SOUVIE JEAN-CLAUDE
IPC: C07D209/34
Filed: 2001-03-30
Abstract: A process for the industrial synthesis of N-[(S)-1- carboxybutyl]-(S)-alanine esters of formula (I), wherein R represents a linear or branched (C1-C6)alkyl group. This process includes the condensing of sodium pyruvate with an S-norvalinate ethyl compound, with hydrogenation catalysed by 5% palladium-on-carbon, in water, at a pressure of from 1 to 20 bar, at a temperature of from 10 to 60°C and in the presence of sodium hydroxide in an amount from 0.1 to 0.2 mol per mol of S-norvalinate ethyl compound used, to yield the compound of formula (I) directly, in optically pure form, following acidification of the reaction mixture to a pH of from 2.8 to 4.5 and then filtration. The compounds of formula (I) are useful in the synthesis of perindopril and pharmaceutically acceptable salts thereof.
Patent NZ-522715-A (NZ)
Title: Alpha,beta-unsaturated sulfones for treating proliferative disorders
Inventor: REDDY E PREMKUMAR
IPC: C07D277/26
Filed: 2001-04-13
Abstract: Compounds of formula (I) with Q1 and Q2 either  phenyl radicals or aromatic radicals of disclosed formulas.
Patent NZ-522863-A (NZ)
Title: 2' branched nucleosides in methods and compositions for the treatment of hepatitis C
Inventor: SOMMADOSSI JEAN-PIERRE
IPC: A61P1/16
Filed: 2001-05-23
Abstract: A method and composition for treating a host infected with hepatitis C comprising administering an effective hepatitis C treatment amount of a 2'-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided.
Patent NZ-523821-A (NZ)
Title: Hydraulic swage press
Inventor: VAN ESSEN FRED
IPC: B21J13/02
Filed: 2001-07-19
Abstract: The present specification discloses a swaging press including a piston member (30) cooperable with a plurality of die shoes (40) to drive the die shoes inwardly upon axial movement of the piston member (30) during a swaging operation, the piston member (30) having a frusto-conical recessed region (31) divided into a plurality of circumferentially disposed bearing surface zone (33) of a defined axial length, each of the bearing surface zones (33) having an inner axial end (35) with a numerical radius of curvature less than or equal to the radius of curvature of a circular line (36) forming the lateral edges of each of the bearing surface zones (33) at the inner axial end (35) whereby at least 50 % of the outer bearing surface (41) of each said die shoe (40) remains in bearing engagement with the adjacent said bearing surface zone (33) over the axial movement of the piston member (30) during a swaging operation.
Patent NZ-523927-A (NZ)
Title: Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
Inventor: KLAVENESS JO
IPC: A61K41/00
Filed: 2001-07-25
Abstract: A compound for use in photochemotherapy or diagnosis comprises formula I: R22N-CH2-COCH2-CH2CO-OR1 (I) wherein R1 is a C1 or C2 alkyl group substituted by one or more aryl groups and R2 independently represents H or an optionally substituted alkyl group. The aryl group may also be optionally substituted wherein the substituents are selected from hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, nitro, oxo, fluoro, -SR3, -NR32 and PR32 groups and the alkyl group is optionally interrupted by one or more -O-, -NR3-, -S- or PR3 groups; wherein R3 is H or C1-6 alkyl. A pharmaceutical composition can comprise the compound. An in vitro method of diagnosis of abnormalities or disorder comprises admixing a sample of body fluid or tissue with the compound, exposing the mixture to light, ascertaining the level of fluorescence and then comparing the level of fluorescence to control levels.
Patent NZ-525370-A (NZ)
Title: Safety stirrup
Inventor: BARNES MAURICE
IPC: B68C3/02
Filed: 2001-10-29
Abstract: A riding stirrup includes a foot-receiving part (1) and a suspension part (2) which is suspended from a strap (14). The foot-receiving part is pivotally received on a tongue (7) held by a flange (8) and a retaining plate (9) which is secured to the suspension part by snap fasteners (11). Normal downward forces on the stirrup do not dislodge the retaining plate, but if the rider falls from the saddle the foot-receiving part pivots in a direction to lever the fasteners apart. The retaining plate is thus freed allowing the foot-receiving part to separate from the suspension part.
Patent NZ-526564-A (NZ)
Title: Metered dose inhaler for salmeterol xinafoate
Inventor: GODFREY ANNE PAULINE
IPC: A61K9/00
Filed: 2001-12-21
Abstract: A container comprising a canister sealed with a metering valve, having a metering chamber, which contains a pharmaceutical aerosol formulation consisting essentially of (A) particulate salmeterol xinafoate optionally in combination with another drug useful in inhalation therapy, suspended in (B) a liquefied propellant gas comprising 1,1,1,2,3,3,3- heptafluoro-n-propane, 1,1,1,2-tetrafluoroethane or a mixture thereof; wherein the formulation contains less than 0.01% w/w of surfactant and components having polarity higher than the liquefied propellant gas; the valve characterised in that, it contains one or more sealing gaskets substantially constructed from of a polymer of EPDM and the metering chamber surface presents a substantially fluorinated surface to the formulation.
Patent NZ-530182-A (NZ)
Title: Toilet system
Inventor: FREEMAN MARK JOHN
IPC: C02F1/02
Filed: 2002-05-23
Abstract: A toilet system includes a toilet (10) and a waste bin (12) adapted to receive waste from the toilet (10). An auger (30) is arranged to operatively cooperate with the waste bin (12) whereby at least some of the waste collected in the bin (12) can be extracted via the auger (30). The waste bin (12) includes a floor (14,16), which is sloped inwardly to form a channel (18). The floor (14,16) has a plurality of perforations, which allow passage of liquid there through. Walls (24,26) extend upwardly from a perimeter of the floor (14,16) and the auger (30) is positioned at a lower portion (32) of the channel (18).
Patent NZ-534098-A (NZ)
Title: Cycloalkyl inhibitors of potassium channel function
Inventor: LLOYD JOHN
IPC: C07D295/185
Filed: 2003-01-31
Abstract: Disclosed are cycloalkyl compounds of formula I wherein m is 1; p is 1 or 2; and other substituents are as defined in the specification. These compounds are useful as inhibitors of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, more especially inhibitors Kv1.5 which has been linked to the ultra-rapidly activating delayed rectifier K+ current IKur), also disclosed are methods of using such compounds in the prevention and treatment of arrhythmia and IKur-associated disorders, and other disorders mediated by ion channel function, and pharmaceutical compositions containing such compounds.
Patent NZ-535146-A (NZ)
Title: Genetic products differentially expressed in tumors and use thereof
Inventor: SAHIN UGUR
IPC: G01N33/574
Filed: 2003-03-12
Abstract: A pharmaceutical composition comprises an agent that inhibits expression or activity of a tumor-associated antigen which has a nucleic acid encoded sequence selected from the group consisting of: (a) a nucleic acid sequence selected from the group consisting of SEQ ID NOs: 19-21 and 54-57, a functional fragment or derivative thereof; (b) a nucleic acid that hybridizes with the nucleic acid of (a) under stringent conditions; (c) a nucleic acid which is degenerate with respect to the nucleic acid of (a) or (b), and (d) a nucleic acid which is complementary to the nucleic acid of (a), (b) or (c); in which the agent is an antisense nucleic acid coding for the tumor-associated antigen, and/or an antibody which binds selectively to the tumor-associated antigen. The pharmaceutical composition can be used in the manufacture of a medicament for treating, diagnosing or monitoring a disease characterised by expression of the tumor-associated antigen. Also described are use of host cells, cytolytic or cytokine releasing T cells, antibodies, methods of detection or diagnosing a disease characterised by expression of a tumor-associated antigen.
Patent NZ-538616-A (NZ)
Title: Antifreeze proteins isolated from forage grasses and methods for their use
Inventor: DEMMER JEROEN
IPC: C12N15/29
Filed: 2003-09-09
Abstract: Disclosed are isolated polynucleotides encoding antifreeze polypeptides, together with expression vectors and host cells comprising such isolated polynucleotides. Methods for the use of such polynucleotides and polypeptides are also disclosed.
Patent NZ-540797-A (NZ)
Title: Tamper evident closure assemblies
Inventor: SCOTT EDWARD SEAN
Filed: 2002-12-20
Abstract: A one piece overcap moulding having an overcap region, a internally threaded skirt region, and a frangible link between the overcap and the threaded skirt region, and a dispensing component or assembly located within the one piece overcap moulding sealingly engaged thereto. The moulding and the component can or do define a fully enclosed space. The one piece overcap and the internally threaded skirt region do not have intermittent bridging as the frangible link nor other form(s) providing any opening through the one piece overcap moulding above the sealed engagement with the dispensing component or assembly.
Patent NZ-544234-A (NZ)
Title: Juicer with inwardly directed formations arranged to constrict the feed tube
Inventor: BARKER MARIO JOHN CHAVES
IPC: A47J43/25
Filed: 2004-07-13
Abstract: This invention concerns a juicer, that is a machine for extracting the juice from fruit and vegetables. Such machines are used domestically and also commercially in restaurants, cafes and juice bars. The invention comprises an electric motor, a shredder mounted for rotation by the motor, a feed tube (43) to deliver pieces to be juiced to the shredder for juicing, wherein the feed tube has an inner diameter of more than 75mm, and three, or more, inwardly directed formations (100) are arranged to constrict the interior of the feed tube. The inner diameter of the feed tube may be large enough for a typical apple to pass through it whole such as 85mm or more. The inwardly directed formations serve to prevent the insertion of a hand or arm into or through the feed tube despite its large diameter.
Patent NZ-554145-A (NZ)
Title: Case for portable electronic device
Inventor: SIRICHAI SAHARUT
Filed: 2007-03-27
Abstract: Cases for portable electronic devices are disclosed, including cases that provide support as well as protection. Cases may be configured to contain a video-capable electronic device (not shown) and may both protect the device and allow it to maintain a hands-free viewing position. Embodiments include a first panel (110) having an upper portion (111) and a lower portion (112) separated from each other by a hinge line (113), a second panel (120) spaced apart from and coupled to the upper portion of the first panel by a first sidewall (160) and a second sidewall (170), and a third panel (130) spaced apart from and coupled to the lower portion of the first panel by a third sidewall (180) and a fourth sidewall (190). The first panel is capable of being folded along the hinge line into a flexed position.
Patent NZ-555665-A (NZ)
Title: Panel connection system
Inventor: COUMAROS ANDREW
Filed: 2007-06-06
Abstract: A connection system for connecting two precast wall panels after erection comprises channels cast into the two panels and a connection plate applied after erection and bolted into locking plates slidable within the channels to permit a degree of adjustment. The connection between the locking plate and the channels ensures that the plate cannot rotate and thereby slip under high cantilever loading which can arise when one of the two panels is a suspended panel with its lower edge raised from the ground.
Patent NZ-556650-A (NZ)
Title: Reducing by-catch of seabirds
Inventor: JUSSEIT HANFRIED
IPC: A01K97/00
Filed: 2005-12-23
Abstract: An apparatus for reducing by-catch of seabirds or turtles during fishing include a fish hook (220) and a barrier or shield (227) mounted in a position relative to the fish hook (220) such that the barrier (227) reduces or prevents hooking of a seabird or turtle by the fish hook or ingestion of the hook by a seabird or turtle. The apparatus includes a degradable component (226) that degrades when placed in water such that when the degradable component degrades the barrier moves away from the position relative to the fish hook or no longer exists to allow the fish hook to be taken by a fish. The degradable component (226) may be a retaining means or a mounting means. The degradable component may form part of, or all of, the barrier.
Patent NZ-568229-A (NZ)
Title: Device for producing a stacking projection on a container wall and container with same
Inventor: D AMATO GIANFRANCO
IPC: B31B50/00
Filed: 2006-10-13
Abstract: Device for producing a stacking projection on the inner side of a container wall comprises a splaying mandrel and a support ring open at the top Those are movable relative to one another between a standby position and a deformation position The splaying mandrel comprises at least in some places a retaining indentation running externally circumferentially and the support ring comprises at least in some places a notch projection running internally circumferentially Through the interaction of those indentation and projection in the deformation position the stacking projection can be produced, wherein in the deformation a gap width between in particular the retaining indentation and the notch projection in a border section of the circumference is greater than the gap width between the other circumferential sections The corresponding container has an inner wall and an outer wall,; in each case narrowing conically downwards The walls are at least joined together at the upper edge of the container, wherein on the inner side of the inner wall a de-nesting means, protruding inwards, is formed as a stacking projection On that, another container when inserted in the container is supported A distance between said stacking projection and the bottom of the projection, is at least slightly larger than a distance between said bottom and a potential contact starting point at which the outer container when inserted in the inner container starts to contact the inner side of the inner wall of the inner container.
Patent NZ-571305-A (NZ)
Title: System and methods for transporting or storing oxidatively-degradable foodstuff with a pressure sealable tote with a hydrogen source
Inventor: BELL LAURENCE D
IPC: A23L3/3418
Filed: 2007-06-28
Abstract: A flexible pressure-stable sealable tote for use in transporting and/or storing of oxidatively-degradable foodstuffs, preferably fish. The tote includes a fuel cell with an anode and a cathode capable of converting hydrogen and oxygen within the tote into water. The tote also includes a holding element suitable for maintaining a hydrogen source within the tote or an external hydrogen source which is gaseous communication with the device.
Patent NZ-575961-A (NZ)
Title: Simultaneously deoxygenation and desulphurisation process for producing hydrocarbons from feedstocks containing carboxylic acids / esters and sulfur compounds
Inventor: GUDDE NICHOLAS JOHN
IPC: C07C1/24
Filed: 2007-10-04
Abstract: Disclosed is a simultaneously deoxygenation and desulphurisation process for producing hydrocarbons from feedstocks containing carboxylic acids / esters and sulphur compounds; said process comprises the steps of (a) feeding hydrogen and a reaction composition comprising a carboxylic acid and/or derivative thereof (particularly biological oils, vegetable oils or fats) and sulphur compounds to a reactor; (b) maintaining conditions within the reactor such that the hydrogen reacts with the carboxylic acid and/or derivative thereof to produce one or more oxides of carbon and one or more product hydrocarbons derived from the carboxylic acid and/or derivative thereof, and the sulphur compounds react in the reactor to form hydrogen sulphide, wherein the reaction is catalysed (such as by a catalyst comprising one or more of Palladium, Platinum, Nickel, Ruthenium, Copper, Cobalt, Chromium, Molybdenum, and Tungsten) and is performed at a temperature in the range of from 200 to 430 °C and a pressure in the range of from 20 to 200 bara (2 to 20 MPa); (c) removing from the reactor a product stream comprising unreacted hydrogen, the one or more product hydrocarbons, the hydrogen sulphide and the one or more oxides of carbon from the reactor; (d) feeding the product stream to a flash separator; (e) removing from the flash separator a vapour fraction and a liquid fraction, in which the vapour fraction comprises hydrogen, the hydrogen sulphide and the one or more oxides of carbon, and the liquid fraction comprises the one or more product hydrocarbons; (f) stripping the hydrogen sulphide from the vapour fraction using a liquid amine; and (g) recycling at least a portion of the vapour fraction to the reactor; wherein the process comprises controlling one or more of the reaction temperature, the partial pressure of hydrogen in the reactor, the total pressure in the reactor, and the mole ratio of hydrogen to carboxylic acid and/or derivative thereof in the reactor such that the total concentration of the one or more oxides of carbon in the vapour fraction from the flash separator is maintained at or below a value of 1 wt%.
Patent NZ-578344-A (NZ)
Title: Heterocyclic nitrogen containing polymer coated analyte monitoring device and methods of use
Inventor: OUYANG TIANMEI
IPC: A61B5/05
Filed: 2008-01-31
Abstract: Disclosed is an electrochemical sensor, comprising: a working electrode comprising: a sensing layer in contact with a conductive material of the electrode; a diffusion limiting membrane layer disposed over the sensing layer, wherein the membrane comprises a crosslinker and a nitrogen containing polymer which has not been quaternized with substituents and has no pendent groups; and a counter electrode in electrochemical communication with the working electrode.
Patent NZ-582329-A (NZ)
Title: Improving memory in subjects with mini-mental state examination of 24-26
Inventor: KAMPHUIS PATRICK JOSEPH GERARDUS HENDRIKUS
IPC: A23L33/15
Filed: 2008-06-20
Abstract: Provided is the use of: a.) uridine or uridine phosphate; and b) docosahexaenoic acid and/or eicosapentaenoic acid in the manufacture of a product for improving impaired delayed recall function in a subject, wherein said product is enterally administered to the subject.
Patent NZ-588176-A (NZ)
Title: Method and apparatus for energy generation using the flow of water into a high pressure sealed chamber
Inventor: SCANDLE PHILLIP JAMES
IPC: F03B13/10
Filed: 2011-05-13
Abstract: An apparatus for generating energy is disclosed. The apparatus comprises a high pressure sealable main chamber (1) having an outlet (5) and an inlet (4) located in the vicinity of a base of the main chamber (1). The inlet (4) includes an inlet flow control device (3) having an open position and a closed position. In the open position the liquid can flow into the main chamber (1). The outlet (5) has an opening located at a position which, in use, is below the level of liquid in the main chamber (1). The apparatus further comprises at least one energy conversion device that is configured to extract energy from the flow of liquid into, out of or through the main chamber (1). The method of generating energy comprises the following steps: a) Inserting a resilient material into the main chamber (1) and sealing it; b) Locating the inlet (4) of the main chamber (1) at a depth within a body of liquid; c) Setting the inlet flow control device (3) to an open position to enable the liquid to flow into the main chamber (1) this compressing the resilient material d) Setting the inlet flow control device (3) to the closed position to enable the resilient material in the main chamber (1) to expand and displace at least some of the liquid in the main chamber out through the outlet (5) e) Repeating steps c) and d) to create a flow of fluid and resilient material through the main chamber (1); and f) Extracting the energy from the flow of the liquid through the main chamber (1), and/or flow of the liquid into or out of the main chamber (1).
Patent NZ-589668-A (NZ)
Title: Methods and apparatus for ultrasonic cleaning
Inventor: BATES DARREN M
IPC: A47L15/13
Filed: 2009-05-08
Abstract: Disclosed is a method of cleaning a surface by applying highly propagating ultrasonic energy to said surface, the method comprises immersing at least a portion of the surface into a fluid, wherein said fluid is in contact with an highly propagating ultrasonic energy emitting assembly; and emitting highly propagating ultrasonic energy from the assembly into the fluid to generate cavitation at the surface thereby cleaning said surface.
Patent NZ-593228-A (NZ)
Title: Gene expression markers (inhba) for colorectal cancer prognosis
Inventor: COWENS WAYNE
IPC: C12Q1/68
Filed: 2007-01-11
Abstract: Disclosed is a method of predicting clinical outcome for a human subject following surgical resection of colorectal cancer, the method comprising: a.) Determining a normalised level of RNA transcript of INHBA, or an expression product thereof, in a biological sample comprising cancer cells obtained from said human subject; and b.) Predicting the likelihood of a positive clinical outcome for said human subject by comparing said normalised level to gene expression data obtained from colorectal cancer reference samples derived from patients with colorectal cancer, wherein increased normalised level of an RNA transcript of INHBA, or an expression product thereof, is negatively correlated with an increased likelihood of a positive clinical outcome.
Patent NZ-597767-A (NZ)
Title: Antibodies to IL-6 and use thereof
Inventor: GARCIA-MARTINEZ LEON
IPC: A61K39/395
Filed: 2008-05-21
Abstract: 597767 Provided is an anti-human IL-6 antibody or antibody fragment comprising a variable heavy chain that possesses at least 90% sequence identity to a specified variable heavy chain and/or a variable light chain that possesses at least 90% sequence identity to it or an antibody that having the same epitopic specificity as an antibody or antibody fragment comprising the VH and VL of the specified sequences. Further provided are methods of making the antibody and its use to treat cancers and various other diseases.
Patent NZ-599298-A (NZ)
Title: Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
Inventor: ZIMDAHL-GELLING HEIKE
IPC: A61K31/44
Filed: 2010-11-26
Abstract: Disclosed is the use of a pharmaceutical compound comprising a DPP-4 inhibitor for the manufacture of a medicament for use in a method of treating type 2 diabetes mellitus, said method comprising testing that the patient has one or more single nucleotide polymorphisms (SNPs) in the gene coding for TCF7L2 and administering the pharmaceutical compound to the patient.
Patent NZ-601868-A (NZ)
Title: Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
Inventor: CERAMI ANTHONY
IPC: A61K38/03
Filed: 2009-01-22
Abstract: Disclosed is the use of an isolated peptide consisting of no more than 15 amino acids and comprising an amino acid sequence of WEHVNAIQEARRLL, i.e., SEQ ID NO: 114, in the manufacture of a pharmaceutical composition for use in a method for preventing, treating, ameliorating or managing cancer or a neoplastic disorder.
Patent NZ-627684-A (NZ)
Title: Bone screw and method for manufacturing the same
Inventor: WILLERT WAYNE A
IPC: F16B25/00
Filed: 2013-02-07
Abstract: A bone screw (1900) for osteosynthesis is described. The screw is designed to both reduce friction and the requisite torque when tapping bone and to allow for better purchase once set in the bone, thus reducing the likelihood of loosening or back-out. The screw achieves this with grooves on the shaft (1710, 1712) or on the thread (1902, 1904) which increase the surface area.