baber/WOPTO huggingface dataset:
Patent EP-1603558-B1 (EP)
Inventor: DATTA DEBASHISH
IPC: C07D209/42
Filed: 2003-02-28
Granted: 2008-05-21
Abstract: A process for preparation of perindopril of formula (II) and salts thereof which is simple, safe, convenient and cost-effective. The process involves reaction of compound of formula (I), wherein X is chlorine or bromine with compound of formula (VII) wherein A signifies that the six-membered ring of the bicyclic system is either saturated or unsaturated to give compound of formula (VIII), wherein A is as defined above, followed by catalytic hydrogenation of the compound of formula (VIII) thus obtained to give the perindopril of formula (II). The above process for the manufacture of perindopril would specifically avoid the use of harmful chemicals like phosgene or costly coupling agents like dicyclohexylcarbodiimide and 1-hydroxybenxotriazole usually used for such manufacture. The process would also not require any intervention of a catalyst and does not require any alkaline or acidic reaction conditions. Importantly, the process provides for manufacture of perindopril with high stereoselectively giving perindopril (II) having (S)-configuration in all the five chiral centres of the molecule, conforming to pharmacoepeial specifications. The invention also relates to a method for preparation of the compound of formula (I) and also to a method for preparation of N-[(S)-1-carbethoxybutyl]-(S)-alanine of formula (III) used in the process.
Patent EP-1516488-B1 (EP)
Inventor: KAMPERMAN FRANCISCUS L A J
IPC: H04N7/24
Filed: 2003-05-27
Granted: 2009-05-13
Abstract: A broadcast data stream that contains a stream of encrypted data and a stream of messages. Data in successive segments of the stream of encrypted data is decryptable with successive decryption information from the messages. The stream of encrypted data is stored upon reception. The items with decryption information for the encrypted data are stored independently retrievable from the stream. Additionally synchronization information is generated and stored to link respective points in the stored stream of encrypted data to respective ones of the items with decryption information. During replay of a stored part of the stream of encrypted data the items with decryption information for the points in said stored part are retrieved. The retrieved items with decryption information are combined with the stream during replay at times selected under control of the synchronization information. The stream is fed to a decoder and the decryption information is combined with the stream by feeding the decryption information to a secure device, which in response to the decryption information feeds control words to the decoder.
Patent EP-1507691-B1 (EP)
Inventor: ZIEROLF MICHAEL LEE
IPC: B60T8/00
Filed: 2003-05-21
Granted: 2006-09-27
Abstract: An antiskid brake controller utilizes measured wheel speed to provide brake control for a vehicles, such as an aircraft. The antiskid brake controller controls a braking operation of a wheel of a vehicle based on a wheel speed signal provided by a wheel speed sensor coupled to the wheel. The antiskid brake controller includes a deceleration threshold generator that selects a deceleration threshold based on the ability of the wheel to hold a pilot commanded brake pressure without excessive skidding. The deceleration threshold is a function of a wheel speed reference signal omegaref.
Patent EP-1497023-B1 (EP)
Inventor: GUTSOL ALEXANDER
IPC: B01D53/72
Filed: 2003-03-24
Granted: 2009-09-16
Abstract: A method for abatement of volatile organic compounds (VOC) in an exhaust gas stream is disclosed. That method comprises passing an exhaust gas stream ( 40 ) through a pulsed corona discharge chamber ( 10 ) in the presence of flowing water ( 30 ) to form one or more oxidation products that dissolve in the water and provide an effluent water stream ( 42 ) containing the oxidized VOC and an effluent gas stream ( 32 ) having a deleted amount of VOC. The pulsed corona discharges at a rate of about 0.01 to about 2 kHz. The ratio of the water spray rate to the exhaust gas flow is about 0.2 milliliters/minute at one standard liter per minute of exhaust gas flow, and an expenditure of not more than 50 eV per molecule of VOC is utilized. The method provides a destruction and removal efficiency of about 90 percent or more.
Patent EP-1487416-B1 (EP)
Inventor: LERNER ITZHAK E
IPC: A61K9/16
Filed: 2003-03-25
Granted: 2009-12-02
Abstract: Provided are microparticles of active pharmaceutical ingredients, drug delivery vehicles comprising same, and methods for making them.
Patent EP-1536837-B1 (EP)
Inventor: HOEMANN CAROLINE
IPC: A61K47/36
Filed: 2003-07-16
Granted: 2010-09-15
Abstract: The present invention provides compositions and methods for tissue repair using a cytocompatible self-gelling cross-linked hydrogel. The composition comprises a biocompatible mixture of chitosan, bifunctional dialdehyde, and hydroxylated polymer, which can be used to immobilize or encapsulate viable cells, or bioactive substances. The method includes the process of mixing bioactive substances, live cells, and/or extracellular matrix components with a cross-linking solution comprising a bifunctional aldehyde-treated hydroxylated polymer such as hydroxyethyl cellulose. The cross-linking solution is then mixed homogenously with a neutral isotonic chitosan solution. The chitosan becomes cross-linked by the bifunctional aldehyde, while the cells are protected from potentially nocive effects of the aldehyde cross-linker by the hydroxylated polymer. The injectable solution retains cell viability and bioactivity, and immobilizes cells at the site of injection or delivery. Depending on the particular application, mixtures of chitosan and bifunctional dialdehyde may be employed. The injectable solution also liberates bioactive substances with controlled release kinetics from the site of injection.
Patent EP-1571138-B1 (EP)
Inventor: MORI NOBUAKI
IPC: C07C67/48
Filed: 2003-12-09
Granted: 2007-02-28
Abstract: The present invention provides processes for producing a (4E)-5-chloro-2-isopropyl-4-pentenoate and an optical isomer of the (4E)-5-chloro-2-isopropyl-4-pentenoate, namely a process for producing a (4E)-5-chloro-2-isopropyl-4-pentenoate represented by the following formula (4), which comprises reacting a compound represented by the following formula (2) in the presence of an aprotic solvent (II) with a base (II) and then with (1E)-1,3-dichloro-1-propene to give a compound represented by the following formula (3), and dealkoxycarbonylating either ester in the compound represented by the following formula (3), and a process for producing a (S)-(4E)-5-chloro-2-isopropyl-4-pentenoate represented by the following formula (5), which comprises optically resolving a (4E)-5-chloro-2-isopropyl-4-pentenoate represented by the formula (4) obtained by the above-mentioned process (wherein R is a lower alkyl group or an aralkyl group). <CHEM> <CHEM>
Patent EP-1534335-B1 (EP)
Inventor: KOENIG SCOTT
IPC: A61K39/395
Filed: 2003-08-14
Granted: 2011-12-07
Abstract: The present invention relates to antibodies or fragments thereof that specifically bind Fc³RIIB, particularly human Fc³RIIB, with greater affinity than said antibodies or fragments thereof bind Fc³RIIA, particularly human Fc³RIIA. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.
Patent EP-1568342-B1 (EP)
Inventor: SAYAMA YASUSHI
IPC: A61F13/56
Filed: 2003-11-25
Granted: 2012-04-04
Abstract: A disposable diaper 1 is formed in one of front and rear waist regions 6, 7 with first wings 18 which are elastically stretchable in a waist-surrounding direction and these first wings 18 are provided on respective body facing surfaces 2 with first fastener means 23. The other waist region is provided on its undergarment facing surface 3 with, in addition to second fastener means 26, anti-slip zones 44 exhibiting a desired average kinetic frictional force relative to the body facing surface 2 of the first wings 18. <IMAGE>
Patent EP-1704221-B1 (EP)
Inventor: HERMANN GERHARD
IPC: C12M1/107
Filed: 2003-07-17
Granted: 2010-03-10
Abstract: The invention relates to a method for separating biogas, fermented biomass and water produced in a biogas fermenter by fermentation of a biosubstrate. After fermentation of the biosubstrate used, the degassed fermented biomass or fermented material, by stopping the agitation, is subjected to a sedimentation phase in a biogas fermenter (1). Once the solid biomass has sedimented and the suspended matter floats on the surface, the sedimentation layer forming the sedimented matter is removed. Said sedimentation layer is subjected to an additional fermentation step in a separate closed sedimentation fermenter (2). The biogas and humidity thereby produced are led into the gas-carrying section of the biogas fermenter (16) and the sedimentation water is led in a second step into a separate sedimentation water basin (3) or directly into ponds (5).
Patent EP-1422142-B1 (EP)
Inventor: GALASSI CESARINO
IPC: B65D75/32
Filed: 2001-03-28
Granted: 2006-01-25
Abstract: Process for the production of plastic blister packs (13) containing liquid perfumes, wherein forming and sealing are carried out by using a horizontal apparatus, in which for the transport of the films (2 and 6) the fluid of the hydraulic circuit is replaced with air including oil.
Patent EP-1454728-B1 (EP)
Inventor: HAUENSTEIN HANSRUEDI
IPC: B28D1/18
Filed: 2004-03-02
Granted: 2006-08-23
Abstract: The milling machine has a milling unit which is connected to the base frame (1) via a transmission flange (22) so that it can turn and be removed. There is an electric motor on one side of the transmission flange and a milling tool (23) on the other. The milling unit and the holder are connected by a connecting screw (7) to the base from so that they can be detached from it.
Patent EP-1574590-B1 (EP)
Inventor: KAINER KARL ULRICH PROF DR
IPC: B21C23/00
Filed: 2004-03-11
Granted: 2007-04-25
Abstract: The method of producing profiled extrusion is magnesium or other light metal uses a press assembly (10) to force the blank material through a die (14) with the required profile (16). The blank light metal uses a grain refining additive such as Zirconium, strontium or calcium. The grain refiner can be a rare earth metal.
Patent EP-1475219-B1 (EP)
Title: Tool provided with a laserbeam for joining synthetic materials  by the use of a filler material
Inventor: EBERT THOMAS DR
IPC: B29C65/16
Filed: 2004-05-05
Granted: 2008-07-30
Abstract: Hand-held laser welder for plastic workpieces has changeable nozzles (3) with a slot (12), through which the laser beam emerges. These contain feed rollers (13, 14) for a rod (11) of hot melt adhesive.  Independent claims are included for: (a) a method for welding plastic workpieces using the hand-held welder in which it is moved along the junction between the workpieces while the adhesive adheres to the joint; and (b) a hot melt adhesive containing an IR absorbing pigment such that the half value length is one third of its thickness.
Patent EP-1604617-B1 (EP)
Inventor: LIN CHIH-I
IPC: A61B17/70
Filed: 2004-06-08
Granted: 2006-11-02
Abstract: A vertebral retrieval device (10) includes a retrieval rod (20) which is gripped firmly in a receiving slot (31) of a fixation seat (30) between two grooves of a pressing element (63) and a C-shaped ring (50). The C-shaped ring (50) rests on a spherical head fastening screw (40), a spherical head (42) of which is received in the fixation seat (30) and a shank of which is protruding from a through hole (32) provided in a bottom of the fixation seat (30). The pressing element (63) is pressed against the retrieval rod (20) by a pressing screw (62), which is threaded into a threaded hole (612) formed in a fixation element (61) mounted in the receiving slot of the fixation seat (30).
Patent EP-1495940-B1 (EP)
Inventor: BEN RHOUMA ABDEL KARIM
IPC: B62D1/19
Filed: 2004-06-30
Granted: 2007-12-26
Abstract: The device has a steering column mounted in a support assembly (6) that is provided with fixed and movable support units (8, 9). A metallic wire (4) is arranged at an exterior. A stress generator (7) is connected to the fixed support unit and arranged at the side of a portion of the metallic wire. The generator supplies a variable stress for deforming the metallic wire and adapts itself to shock.
Patent EP-1518815-B1 (EP)
Inventor: ROSSIGNOL ERIC
IPC: B66B7/00
Filed: 2004-09-22
Granted: 2006-06-21
Abstract: The sliding door for a lift shaft (11) has a door leaf (12.1) which slides across so that its edge closes the gap between itself the edge of a frame (16) containing the box (18). The box is accommodated in a vertical frame member (14.1) extending from the floor to the top of the frame opening. There is a floor indicator (20) on the front of the box and an access lid (17) on the side. The frame member has a joggle and the width at the front (16.1) is greater than the width (16.21) of the side facing the shaft.
Patent EP-1531199-B1 (EP)
Inventor: KAYSER FRANZ
IPC: D21G1/00
Filed: 2004-11-04
Granted: 2009-01-21
Abstract: The super calender (1), to process paper webs (20), has a roller stack (2) of two end rollers (4,5) and at least three intermediate rollers (7-11) forming nips (14-19). The hard end roller (4) is next to a soft intermediate roller (7), and is powered by a drive (22,23) with meshing teeth in a given tooth count. The product of the rotary frequency of the powered end roller and the tooth count is not equal to a whole number multiple of the neighboring intermediate roller rotary frequency. The roller stack has an uneven number of rollers, with two soft rollers at the center forming an alternating soft nip (9,10;7,9).
Patent EP-1525958-B1 (EP)
Inventor: KONEN BRUCE P
IPC: B23D29/00
Filed: 2004-10-08
Granted: 2009-03-11
Abstract: A cable cutter (10) for attachment to a power drill (12) has a housing (17,18), first (26) and second (28) cutting blades connected to the housing for movement relative to one another and a drive assembly (24) releasably engageable with the chuck (14) of the drill and operatively engaged with at least one of the cutting blades. The drive assembly includes a worm (64) mounted on a drive shaft (36), a worm gear (68) and a drive gear (88) mounted on a main shaft (74), and a segment gear (128) formed on one of the cutting blades. The worm and worm gear which are in engagement, as are the drive gear and segment gear. The main shaft is supported in the housing by three bearings. A torque arm (34) is attached at one end to the housing and adapted at its other end to engage the handle (16) of the drill. A reversible stabilizing handle (30) attaches to the housing to allow the user to securely grip the housing during cutting operations.
Patent EP-1541224-B1 (EP)
Inventor: REY GAMALLO JOSE RAMON
IPC: B01F15/02
Filed: 2004-07-13
Granted: 2007-06-06
Abstract: A mixer, attached to a lid (1) that replaces the original container lid, comprises blades (4) on the end of a central rotary shaft (3) connected to a gear mechanism (8, 10) inside a cover (7) on the top of the lid that enables the blades to be rotated by attaching a handle (12) or a power drill (13). The shaft is in the form of two telescopic tubes that allow its length to be adjusted to the depth of the container (2), while a ring (14) on its lower end prevents the blades damaging a plastic pouch lining the container when the product is in such a packaging. Independent claims are also included for a variable-position support on the lid for a drill, pneumatic head or a pulley connected to an external drive motor, as well as an aperture in the lid for fitting an extraction tube containing a rotary endless screw, a pump or applicator probe.
Patent EP-1587417-B1 (EP)
Inventor: DEWING WENDE L
IPC: G08B21/04
Filed: 2004-01-09
Granted: 2007-06-13
Abstract: Système automatisé de surveillance et de réponse qui comporte des capteurs destinés à surveiller une personne et l'environnement de cette personne et un module d'alerte possédant une interface avec les capteurs et adapté pour identifier la présence d'une situation d'urgence concernant la personne ou son environnement. Le module d'alerte est adapté pour produire un message d'alerte à l'intention d'un ou plusieurs intervenants, ledit message d'alerte comportant une première composante de message d'alerte et une composante supplémentaire de message d'alerte. La composante supplémentaire de message d'alerte contient des informations supplémentaires non primaires concernant la personne et / ou l'environnement et indiquant le contexte de la situation d'urgence, dont, par exemple, des données de capteur concernant ladite situation d'urgence.
Patent EP-1586089-B1 (EP)
Inventor: SUH SANG WOON
IPC: G11B7/013
Filed: 2004-01-20
Granted: 2009-04-01
Abstract: A computer-readable storage medium is disclosed, the storage medium comprising an information area, the information area including a first region for a main data, and a second region for control information required to encrypt and/decrypt the main data, said control information being encoded in wobbled pattern, thereby being detected by a push-pull method, wherein said control information is recorded by bi-phase modulation method in such a manner that bit 0 and bit 1 are determined respectively depending on a transition in a direction within a predetermined period.  Further, a method and apparatus for reproducing data therefrom are disclosed.
Patent EP-1594357-B1 (EP)
Inventor: HOLMERTZ NILS ERIK
IPC: A01J5/013
Filed: 2004-02-17
Granted: 2008-04-09
Abstract: A method for analyzing particles in milk on-line during milking of a milking animal comprises the steps of: (i) flowing at least a portion of the milk as obtained during the milking of the milking animal through a measuring chamber (59); (ii) illuminating milk that flows through the measuring chamber; (iii) repeatedly recording two-dimensional digital images of illuminated milk that flows through the measuring chamber, the two-dimensional digital images being recorded through a lens system (49), preferably a microscope; and (iv) analyzing number, size, shape, structure, morphological structure, density and/or composition of particles found in the two-dimensional digital images.
Patent EP-1601575-B1 (EP)
Inventor: FOCKE HEINZ
IPC: B65B19/22
Filed: 2004-03-01
Granted: 2011-06-29
Abstract: La présente invention concerne un procédé pour produire des emballages (23) d'au moins deux paquets (25, 26), respectivement destinés à un groupe de paquets (21, 22) notamment constitué de paquets (de cigarettes) rectangulaires (20). Selon ce procédé, une section unitaire (24) est pliée autour des groupes de paquets (21, 22) le long de lignes de pliage (imprimées) (46, 47) de façon que les parois internes (27) des paquets (25, 26) adjacentes les unes aux autres soient pliées en forme de V entre les groupes de paquets (21, 22). Selon cette invention, la section sensiblement plane (24) est transportée le long d'une voie à section (36) et est au moins partiellement retenue, lors du transport, de façon à plier en forme de V les parois internes (27) le long de lignes de pliage (46) transversales à la direction de transport. La présente invention concerne également un dispositif correspondant pour mettre en oeuvre ledit procédé.
Patent EP-1600509-B1 (EP)
Inventor: NAKAMURA HIROFUMI
IPC: A01H5/10
Filed: 2004-03-02
Granted: 2011-11-02
Abstract: A process for producing a transgenic plant which accumulates a fructooligosaccharide, comprising the step of transforming a plant with a gene construct comprising a gene encoding  beta -fructofuranosidase capable of converting sucrose into a fructooligosaccharide, and a transgenic plant produced by the process, are disclosed.
Patent EP-1599398-B1 (EP)
Inventor: STEBNICKI JAMES C
IPC: B65G17/06
Filed: 2004-03-02
Granted: 2007-09-19
Abstract: A roller cradle for use in a modular conveying assembly having a direction of travel in which an object is conveyed includes a first half and a second half. Each of the halves include integral hinge members defining a space therebetween. A roller having an axis of rotation substantially perpendicular to the direction of travel is retained in the space.
Patent EP-1602194-B1 (EP)
Inventor: MARCELLI MAURIZIO
IPC: G06F21/34
Filed: 2004-03-05
Granted: 2008-07-23
Abstract: A method for mutual authentication between a subscriber and a communications network, in which a random number is generated at the subscriber's terminal. The random number is sent to the authentication sub-system managing the authentication of the subscriber for the access to the network, e.g., together with a subscriber's identifier. At the authentication sub-system, the identifier is used for checking the credentials of the subscriber. During the authentication process, parameters related to the subscriber's identifier are generated at the authentication sub-system, and the random number is encrypted using a session key formed using such parameters. The encrypted random number is then sent back to the subscriber's terminal, together with information needed to terminal in order to reconstruct the session key. After having reconstructed the session key, the subscriber's terminal decrypts the random number and checks matching with its generated random number. The matching between the two numbers allows the verification, by the subscriber, that the access point to which he/she is connecting is not a fake access point.
Patent EP-1490701-B1 (EP)
Inventor: TARKIAINEN ANTTI
IPC: G01R29/16
Filed: 2004-03-11
Granted: 2011-08-03
Abstract: The invention relates to a method for determining properties of a negative sequence component of a space vector quantity in an electrical network. The method according to the invention includes the steps of determining on the basis of the properties of an ellipse formed by a space vector of the space vector quantity in the electrical network the magnitude of the negative sequence component of the space vector quantity in the electrical network and the location of the negative sequence component of the space vector quantity in the electrical network in relation to a positive sequence component.
Patent EP-1603598-B1 (EP)
Inventor: MERLO ADRIAN
IPC: A61K51/06
Filed: 2004-03-18
Granted: 2008-10-08
Abstract: Radionuclide labelled conjugates based on substance P and analogues thereof with the chelator (DOTAGA) (1-(1-rarboxy-3-carboxy-propyl)-4,7,10(carboxymethyl)-1,4,7,10-tetraazacyclo-dodecane, DOTASA (1-(1-carboxy-2carboxy-ethyl)-4,7,10(carboxymethyl)1,4,7,10-tetraazacyclo-dodecane, or chelator (DOTA) [1,4,7,10 tetraazaacyclo-dodecane 1,4,7,10-tetra(acetic acid)] are useful radiopharmaceutical substances for targeting and treatment of brain tumors, especially gliomas.
Patent EP-1625678-B1 (EP)
Inventor: AHN JOON-KUI
IPC: H04W52/56
Filed: 2004-05-15
Granted: 2012-05-02
Abstract: A method of informing a terminal of uplink synchronization acquisition in a mobile communication system by using downlink transmit power control (TPC) bits. The base station modifies and transmits power control bit patterns according to certain 'N' values defined as a pattern 01 count, and the terminal detects an indicator that informs uplink synchronization acquisition by the modified power control bit pattern. The terminal also maintains the transmit power of the synchronization acquisition timing by increasing the transmit power by an amount equal to the decrease caused by receiving the power control bits for detecting uplink synchronization acquisition.