baber/WOPTO huggingface dataset:
Patent CA-2286177-C (CA)
Title: Composition for gene transfer into cells
Inventor: TANAKA KENICHI
IPC: A61K47/18
Filed: 1998-02-19
Granted: 2011-06-21
Abstract: The present invention is directed to a composition for gene transfer which composition contains a quaternary ammonium salt represented by formula (1):   (see formula 1) wherein A represents (see formula 2) or (see formula 3) (wherein each of R1, R2, R3, R4, and R5, which are identical to or different from one another, represents a C9 - C17 aliphatic group); X1 represents a halogen atom; and n is an integer from 1 to 10 inclusive; and a method for introducing a gene into a cell by use of the composition.     The composition enables effective delivery and expression of a gene which previously could not be effectively expressed in cells due to the low ratio at which the gene is delivered into cells. Therefore, the composition is advantageously used as a gene transfer reagent or a pharmaceutical.
Patent CA-2287296-C (CA)
Title: Method of assessing tissue viability using near-infrared spectroscopy
Inventor: SOWA MICHAEL G
IPC: A61B5/026
Filed: 1998-04-02
Granted: 2009-06-16
Abstract: Prolonged and severe tissue hypoxia results in tissue necrosis in pedicled flaps. We demonstrate the potential of near-infrared spectroscopy for predicting viability of compromised tissue portions. This approach clearly identifies tissue regions with low oxygen supply, and also the severity of this challenge, in a rapid and non-invasive manner, with a high degree of reproducibility. Tissues remaining below a certain hemoglobin oxygen saturation threshold (oxygen saturation index < 1) for prolonged periods (> 6h) became increasingly dehydrated, eventually becoming visibly necrotic. Tissues above this threshold (oxygen saturation index > 1), despite being significantly hypoxic relative to the pre-elevation saturation values, remained viable over the 72 h post-elevation monitoring period. The magnitude of the drop in tissue oxygen saturation, as observed immediately following surgery, correlated with the final clinical outcome of the flap tissue.  These results indicate the potential of near infrared spectroscopy and imaging to monitor tissue oxygenation status and assess tissue viability following reconstructive surgery. Early, nonsubjective detection of poor tissue oxygenation following surgery increases the likelihood that intervention aimed at saving the tissue will be successful.
Patent CA-2290884-C (CA)
Inventor: RIEDL REINHARD
IPC: B25F5/00
Filed: 1999-11-25
Granted: 2007-11-20
Abstract: A handle assembly for a hand-held took and including a handle connectable with the tool housing and having a through-bore for a cable connecting the tool with a power source, a hook-shaped device for suspending the tool and having an element for securing the suspending device on the cable at any arbitrary position on the cable without a possibility of slippage of the suspending device along the cable, and a connection element adjoining the through-bore of the handle for connecting the suspending device with the handle.
Patent CA-2297650-C (CA)
Title: Networking systems
Inventor: MARCONI PETER
IPC: G06F13/12
Filed: 1998-07-21
Granted: 2007-11-27
Abstract: A novel networking architecture and technique for reducing system latency caused, at least in part, by access contention for usage of common bus and memory facilities, wherein a separate data processing and queue management forwarding engine and queue manager are provided for each I/O module to process packet/cell control information and delivers queuing along a separate path that eliminates contention with other resources and is separate from the transfer of packet/cell data into and from the memory.
Patent CA-2309198-C (CA)
Inventor: ALLEN GEORGE DAVID
IPC: A61G3/06
Filed: 1999-10-05
Granted: 2005-06-21
Abstract: An extendible ramp comprising: (i) a chassis; (ii) a first ramp slidable movable relative to the chassis and hingable connected to the chassis; (iii) a second ramp carried by the first ramp and movable relative to the chassis and the first ramp; (iv) means for extending and retracting the first ramp; (v) means for extending and retracting the second ramp; (vi) means for detecting whether the ramp abuts an obstruction when the ramp is being extended; and (vii) means for retracting the ramp if it abuts an obstruction during extension.
Patent CA-2310243-C (CA)
Title: Method and apparatus for monitoring a patient
Inventor: MASSENGALE ROGER
IPC: A61G99/00
Filed: 1998-11-12
Granted: 2008-01-15
Abstract: A remotely programmable and accessible medical device system (10) including an interface unit (14) and a medical device (12) connected to a patient (18) is disclosed. Through a transceiver, such as a telephone (48) or computer (50), a person may obtain status reports from a remotely located medical device in audible, electronic or paper form. In addition, the person may change a protocol associated with the medical device or be alerted to a remote location of an alarm associated with the medical device.
Patent CA-2311318-C (CA)
Inventor: MURPHY MICHAEL PATRICK
IPC: A61K31/66
Filed: 1998-11-25
Granted: 2011-11-01
Abstract: L'invention concerne des composés antioxydants ciblés vers les mitochondries. Un composé de l'invention comporte un cation lipophile couplé de façon covalente à une fraction antioxydante. Dans des modes de réalisation préférés, le cation lipophile est le cation triphénylphosphonium, et le composé est représenté par la formule P(Ph3)<+>XR.Z<->, dans laquelle X est un groupe de liaison, Z est un anion et R est une fraction antioxydante. L'invention concerne également des compositions pharmaceutiques contenant les composés antioxydants ciblés vers les mitochondries, et des procédés thérapeutiques ou prophylactiques destinés à des patients qui pourraient bénéficier d'un stress oxydatif réduit, ces procédés comportant l'étape consistant à administrer les composés de l'invention.
Patent CA-2318011-C (CA)
Title: Method and apparatus for manufacturing a device
Inventor: POWELL KENNETH G
IPC: B29C45/26
Filed: 2000-09-12
Granted: 2010-08-10
Abstract: A device, preferably a micro-device, is molded from a plastic material by injection molding, compression molding or embossing. A microabrader can be molded having microneedles for abrading the stratum corneum of the skin to form an abraded site in the tissue for enhancing drug delivery. The micro-device is molded using a mold assembly having a silicon molding surface. The silicon molding surface can include a recess corresponding to the desired shape and length of the microneedles. The silicon molding surface enables micron and submicron size features to be molded from polymeric materials without the polymeric material adhering to the mold surface. Micro-devices having molded features having micron and submicron dimensions can be rapidly produced without the use of a release agent.
Patent CA-2318647-C (CA)
Inventor: WATTS JACK L
IPC: B65D1/02
Filed: 1998-01-22
Granted: 2005-11-01
Abstract: L'invention concerne une pièce intérieure (14) comportant un rebord périphérique inférieur (16) fixé à une plaque (11) en carton entourant un orifice (12). Au-dessus du rebord (16) se trouve un bec (17) qui converge vers le haut et qui comporte une nervure cylindrique extérieure (22) de fermeture. Au-dessus du bec (17) se trouve une bande d'ouverture extérieure inclinée (26), au-dessus de laquelle se trouve un bouchon refermable (36) comportant un haut (37), une jupe descendante (38) pourvue de saillies intérieures (39) disposées de manière interrompue et un bouchon mâle (41). La bande d'ouverture (26) est reliée au bec (17) et au bouchon (36) par de fines lignes de séparation horizontales (27, 28). Une languette à tirer (31) sert à détacher la bande d'ouverture (26) du bec (17) et du bouchon (36). Le bouchon (36) est dimensionné de manière que la jupe (38) s'emboîte sur l'extérieur du bec (17) avec les saillies (39) formant une fermeture amovible en dessous des saillies (22), alors que le bouchon mâle (41) est en prise étanche avec l'intérieur du bec (17) afin d'éviter toute fuite.
Patent CA-2320334-C (CA)
Inventor: SAINT VICTOR MARIE-ESTHER
IPC: D21C3/02
Filed: 1999-01-28
Granted: 2007-08-07
Abstract: Enhanced removal of lignin and other extractives in a pulping process is achieved by contacting wood chips and the like with a liquid mixture comprised of white liquor and aminoalkoxylsilane and optionally, one or more nonionic and/or anionic surfactants.
Patent CA-2327014-C (CA)
Title: Method and apparatus for providing selectable output voltages
Inventor: OWEN DONALD W
IPC: H01F29/04
Filed: 2000-11-22
Granted: 2005-04-12
Abstract: A transformer is provided along with a combination of bridging tap-changers to provide a wide range of selectable output voltages in discrete, relatively small voltage steps wherein the highest voltage is more than double the lowest output voltage. Relatively inexpensive off-the-shelf, bridging tap-changers are utilized in conjunction with transformer winding schemes to provide a low winding loss ratio.
Patent CA-2327135-C (CA)
Title: Mass spectrometer system including a double ion guide interface and method of operation
Inventor: SCHOEN ALAN E
IPC: H01J49/06
Filed: 2000-11-29
Granted: 2004-01-27
Abstract: There is described an interface for delivering ions generated in an ion source into a mass analyzer in a chamber under vacuum pressure. In particular, the interface employs two consecutive ion guides operated to dissociate adduct ions formed in the ion source or high pressure regions of the interface between the ion source and the mass analyzer, thus improving the limit of detection or limit of quantitation of the mass analyzer by increasing the analyte ion current.
Patent CA-2333388-C (CA)
Title: Detergent tablet
Inventor: BENNIE BRENDA FRANCES
IPC: C11D3/42
Filed: 1999-07-09
Granted: 2005-04-05
Abstract: A multi-phase detergent tablet for use in a washing machine, the tablet comprising: a) a first phase in the form of a shaped body having at least one mould therein; and b) a second phase in the form of a particulate solid compressed within said mould. The multi-phase tablets provide improved dissolution and cleaning characteristics together with excellent tablet integrity and strength.
Patent CA-2334873-C (CA)
Inventor: DALE GARY
IPC: B63B7/08
Filed: 1999-06-23
Granted: 2007-02-06
Abstract: An automatically inflatable boat (10) including at least two separate compartments (11-15) which are connected to one another by an intercommunicating valve (18, 19, 20, 21) which can be opened to connect adjacent compartments or closed to isolate adjacent compartments. The inflatable boat is provided with a gas pump (30) permanently mounted on the boat and in fluid communication with a connection for receiving pressurized gas of at least one of the inflatable compartments. The pump can be actuated in order to automatically inflate the inflatable compartments of the boat to a preset pressure. Also shown is an inflatable enclosure (50) which can be deflated and inflated and to house an adult and a commode (52) to provide privacy.
Patent CA-2338441-C (CA)
Inventor: ROSZKOWSKI BOGDAN
IPC: F16K5/06
Filed: 1999-08-18
Granted: 2007-01-30
Abstract: The present invention relates to a valve member for a valve of the ball valv e type, including two shell parts rigidly joined together to form a valve member and generally snap-fitted over a frame. The two shell s have opposed seating surfaces and a flow passage extends through the shells and the frame. The valve member includes a means for engagement of a drive mechanism to enable rotation of the valve assembly, wherein said valve member can be rotated to present a sealing surface or alternatively rotated to present a flow path to a water supply when said valve member is located in a sealed fluid passage such as a pipe.
Patent CA-2345466-C (CA)
Title: Sustained release, and comfortable ophthalmic composition and method for ocular therapy
Inventor: WEINER ALAN L
IPC: A61K31/78
Filed: 1999-09-22
Granted: 2007-01-23
Abstract: Numerous drugs cause "stinging" as a side effect when used in the eye, thus increasing patient's discomfort, partly due to the presence of preservatives present in ocular formulations. The present invention is related to a new sustained release ophthalmic formulations with reduced stinging comprising a) at least one basic active; b) a polyanionic polymer; c) an ion exchange resin; and d) a pH adjusting agent. The present invention is also directed to the use of such formulations.
Patent CA-2349416-C (CA)
Title: Improvements in ms/ms scan methods for a quadrupole/time of flight tandem mass spectrometer
Inventor: CHERNUSHEVICH IGOR
IPC: H01J49/34
Filed: 2001-06-01
Granted: 2010-04-27
Abstract: There is provided a method of effecting mass analysis on an ion stream, the method comprising passing the ion stream through a first mass resolving spectrometer, to select parent ions having a first desired mass-to--charge ratio. The parent ions are then subject to collision-induced dissociation (CID) to generate product ions, and the product ions and any remaining parent ions are trapped; the CID and trapping can be carried out together in a linear ion trap. Periodically pulses of the trapped ions are released into a time of flight (TOF) instrument to determine the mass-to-charge ratio of the ions. The delay between the release of the pulses and the initiation of the push- pull pulses of the TOF instrument are adjusted to maximize the duty cycle efficiency and hence the sensitivity for a selected ions with a desired mass-to-charge ratio. This technique can be used to optimize the performance for a parent ion scan, and MRM scan or a neutral loss scan.
Patent CA-2358487-C (CA)
Title: Utilisation de phanquinone pour le traitement ou la prevention des troubles mnesiques
Inventor: GEROLYMATOS PANAYOTIS NIKOLAS
IPC: A61K31/4375
Filed: 2000-01-06
Granted: 2008-11-18
Abstract: L'invention concerne l'utilisation de phanquinone (4,7-phénanthroline-5,6-dione) pour le traitement ou la prévention des troubles mnésiques. Elle concerne également une méthode permettant d'améliorer l'apprentissage ou la mémoire chez un sujet normal, qui consiste à administrer à ce dernier de la phanquinone, éventuellement associée à un ou plusieurs excipients pharmaceutiquement acceptables.
Patent CA-2364529-C (CA)
Title: Mobile device having a protective user interface cover
Inventor: PLETIKOSA VELIMIR
IPC: H04Q7/32
Filed: 2001-12-06
Granted: 2008-11-18
Abstract: A mobile device having a protective user interface cover is provided. The mobile device includes a mobile device housing having a top surface. The user interface is preferably mounted within the top surface of the mobile device, and may include a display, a keyboard, a touch screen, a touch surface, or any other type of user input and display apparatus. The protective cover comprises a protective surface and a positioning mechanism, wherein the protective cover is mounted to the mobile device housing such that the positioning mechanism positions the protective surface between a first position in which the protective surface covers the user interface in the top surface and a second position in which the protective surface does not cover the user interface in the top surface. The protective surface may include a plurality of apertures for receiving user input while the protective cover is in the first position, and may also be at least partially transparent so that a display is visible while the protective cover is in the first position.
Patent CA-2367619-C (CA)
Title: Mouthpiece
Inventor: UENISHI MASAKAZU
IPC: A61C7/08
Filed: 1999-03-26
Granted: 2007-12-04
Abstract: A mouthpiece which has a simple structure, is therefore easy to machine for adjustment, and is extremely inexpensive. The mouthpiece (1) comprises an upper piece (2) to be fitted to the upper jaw dentition, and a lower piece (3) vertically opposed to the upper piece (2) and to be fitted to the lower jaw dentition.  Projections (6, 7) are provided on the opposed surface of one of the upper and lower pieces (2, 3) and project toward the other piece, and a supporting surface (10) for supporting the projections (6, 7) when it comes in contact therewith. An upper dentition fitting groove (5) for fitting the upper piece (2) to the upper-jaw dentition is formed in the upper surface of the upper piece (2), and a lower dentition fitting groove for fitting the lower piece (3) to the lower-jaw dentition is formed in the lower surface of the lower piece (3).
Patent CA-2372016-C (CA)
Title: Turbine moving blade, turbine stationary blade, turbine split ring, and gas turbine
Inventor: TOMITA YASUOKI
IPC: F01D5/12
Filed: 2002-02-14
Granted: 2007-08-14
Abstract: The present invention provides a turbine moving blade, a turbine stationary blade, and a turbine split ring which are capable of restraining the deterioration and peeling-off of a thermal barrier coating easily and surely, and a gas turbine capable of enhancing the energy efficiency by increasing the temperature of combustion gas. The turbine moving blade provided in a turbine constituting the gas turbine includes a platform having a gas path surface extending in the combustion gas flow direction, and a blade portion erecting on the platform. The thermal barrier coating covering the gas path surface is formed so as to go around from the gas path surface to an upstream-side end face and a downstream-side end face of the outer peripheral faces of the platform.
Patent CA-2374561-C (CA)
Title: Culture chamber
Inventor: FULLER JESS PAUL
IPC: C12M3/00
Filed: 2000-05-30
Granted: 2010-03-30
Abstract: A culture chamber for use in a method of culturing microbiological material, which comprises a wall or at least a portion of a wall consisting of a gas-permeable membrane, a textured interior growth surface arranged for contact with the microbiological material being cultured and at least a portion of the external surface gas-permeable membrane being textured to enhance gas permeability. Preferably, the gas-permeable membrane is textured over the majority of both of its surfaces. This culture chamber provides enhanced gaseous exchange between the interior and exterior of the culture chamber and increased surface area within the culture chamber for cell attachment.
Patent CA-2375046-C (CA)
Title: Cross frog
Inventor: KAIS ALFRED
IPC: E01B7/00
Filed: 2000-05-26
Granted: 2005-07-12
Abstract: The invention relates to a cross frog for switches and crossings including a cross frog tip and, extending at both sides thereof, wing rails and running rails, having a basic shape aligned with a main or branch track. To achieve a reduction of the wear of the cross frog tip zone, without requiring reconstruction of the cross frog tip itself or of the guide rail associated therewith or of their orientation to one another, it is proposed that at least one of the running rails, in the zone of the cross frog tip, so deviates from its basic shape that a vehicle with a wheel- or bogie axle traversing the main or branch track experiences an influence of a movement directed away from the cross frog tip.
Patent CA-2378387-C (CA)
Inventor: HACKING EARL L JR
IPC: B03B13/00
Filed: 2000-07-10
Granted: 2005-12-27
Abstract: An apparatus for separating a mixture of mineral particles and recombining t he mineral particles in an alterable, controlled fashion to create a plurality of products each having a predetermined, desired particles size distribution.</ SDOAB>
Patent CA-2378988-C (CA)
Title: Floating pharmaceutical composition comprising an active phase and a non-active phase
Inventor: BESSE JEROME
IPC: A61K9/46
Filed: 2000-08-02
Granted: 2012-04-17
Abstract: The invention concerns a floating pharmaceutical composition consisting of at least a first phase comprising at least a high dose active principle combined with one or several carriers and at least a second phase comprising at least a gas-generating system. The invention also concerns tablets comprising such a pharmaceutical composition and a method for preparing such tablets.
Patent CA-2382996-C (CA)
Title: Mechanical split seal
Inventor: BJORNSON CARL C
IPC: F16J15/34
Filed: 2000-07-21
Granted: 2008-12-02
Abstract: A split seal component (30, 40) includes two seal face segments (200, 400) in two holder halves (102, 104) and a method of assembly and installation. Each seal face segment has a primary sealing surface and a section extending axially from each primary sealing surface. The holder halves are adapted to be joined together to rigidly hold the circular seal face. The holder being constructed and arranged to mount to a shaft (20).
Patent CA-2388601-C (CA)
Inventor: SHORT JOEL E
IPC: H04L29/12
Filed: 2000-10-16
Granted: 2011-07-05
Abstract: La présente invention concerne un procédé permettant de communiquer des informations hôtes durant une session réseau existante. Le procédé comprend les étapes d'établissement pour un hôte de l'utilisateur d'un accès au réseau informatique via une interface de passerelle, la production de paquets de consoles d'informations et de commandes au niveau de l'interface de passerelle, l'envoi à l'hôte de l'utilisateur des paquets de consoles d'informations et de commandes, et la production d'une console d'informations et de commandes sur le moniteur de l'hôte de l'utilisateur qui comprend des données. Les données comprennent en général des données spécifiques de l'utilisateur se basant sur un profil utilisateur, le système de facturation choisi, le niveau de service choisi ou l'emplacement à partir duquel l'utilisateur désire l'accès. L'interface de passerelle est capable de connecter l'utilisateur/l'abonné de manière transparente à de multiples réseaux sans imposer la reconfiguration de l'ordinateur hôte de l'utilisateur. La console d'informations et de commandes permet à l'administrateur de passerelle de fournir des informations à l'utilisateur/l'abonné. La console d'informations et de commandes peut comprendre des informations concernant le marketing, la publicité, les services offerts et des paramètres de surveillance de session réseau et analogue. Dans un mode de réalisation, les informations fournies dans la console d'informations et de commandes peuvent comprendre des données spécifiques de session réseau. L'utilisateur/l'abonné peut alors agir sur les données fournies pour modifier de manière dynamique les caractéristiques d'une session réseau courante.
Patent CA-2390127-C (CA)
Inventor: PEYMAN GHOLAM
IPC: A61F2/16
Filed: 1999-11-04
Granted: 2004-03-16
Abstract: Cette invention se rapporte à une lentille intra-oculaire supplémentaire (116) conçue pour être implantée dans l'oeil, en vue de modifier le système optique de l'oeil comprenant la cornée et le cristallin naturel ou une lentille intra-oculaire (104) déjà implantée dans l'oeil, en vue de créer un système optique modifié ayant des capacités télédioptiques ou d'autres capacités diffractives, afin de corriger la dégénérescence de la macula. Afin de créer ce système de lentille télédioptique, on conçoit cette lentille intra-oculaire supplémentaire (116) avec pour ainsi dire aucune puissance de réfraction, à l'exception d'une partie de lentille négative en son centre. Une fois implantée dans le cristallin naturel ou un cristallin artificiel préalablement implanté et utilisée dans l'oeil sans verre optique externe, cette lentille intra-oculaire supplémentaire (116) permet aux rayons lumineux d'arriver sur la rétine de l'oeil comme ils le feraient en l'absence de lentille intra-oculaire supplémentaire, offrant ainsi une vision sans agrandissement et une vision périphérique non restreinte.
Patent CA-2390241-C (CA)
Inventor: WEISSBROD PAUL A
IPC: B23H7/10
Filed: 2002-06-11
Granted: 2007-08-21
Abstract: A welding electrode wire coil and a method of making the same comprises embedding the inner end of the electrode wire between adhesively bonded convolutions of a wound core made of paper to secure the wire end thereto. The coil is completed by winding the wire about the core and then lacing a cord about the core and the coiled wire thereon in a diamond stitch lacing pattern to retain the coiled wire on the core prior to use. The lacing is provided with a slip knot to facilitate its release relative to the coiled wire and core.