baber/WOPTO huggingface dataset:
Patent CR-20180067-A (CR)
Title: Constructos de anticuerpo para flt3 y cd3
Inventor: HOFFMANN PATRICK
IPC: C07K16/46
Filed: 2016-08-01
Abstract: La presente invención se refiere a un constructo de anticuerpo biespecífico que comprende un primer dominio de unión que se une a FLT3 humana en la superficie de una célula diana y un segundo dominio de unión que se une a CD3 humano en la superficie de una célula T. Además, la invención provee un polinucleótido que codifica el constructo de anticuerpo, un vector que comprende dicho polinucleótido y una célula hospedante transformada o transfectada con dicho polinucleótido o vector. Adicionalmente, la invención provee un procedimiento para la producción del constructo de anticuerpo de la invención, un uso médico de dicho constructo de anticuerpo y un kit que comprende dicho constructo de anticuerpo.
Patent CR-20210407-A (CR)
Title: Microfibrillated cellulose as rheology modifier in high ionic strength agricultural formulations
Inventor: LOPEZ HUMBERTO BENITO
IPC: C05G5/00
Filed: 2020-01-24
Abstract: Described herein, <em>inter alia</em>, is a concentrate including a high ionic strength liquid and a microfibrillated cellulose, and methods of making the same.
Patent CR-20210483-A (CR)
Title: Formulated cannabis oil powder by nanoemulsifycation, methods of producing and uses thereof
Inventor: LARUSH LIRAZ
IPC: A61K36/185
Filed: 2021-02-28
Abstract: The invention discloses particular water-dispersible solid formulation of a cannabinoid or a cannabis extract, wherein they are present in the form of a nanoemulsion, and upon dispersion in water said formulation produces nanoparticles (droplets of a submicron size) with an average size of up to about 500 nm. The present disclosure further relates to methods of making thereof, as well as therapeutic applications in humans for treating disorders and broader application for a range of medical conditions.
Patent CR-20220373-A (CR)
Title: Excipientes poliméricos para aplicaciones de administración de fármacos
Inventor: SILL KEVIN N
IPC: A61K47/34
Filed: 2020-01-10
Abstract: La presente descripción se refiere al campo de la química de polímeros y más particularmente a los copolímeros multibloque que comprenden un bloque de poli(sarcosina) y un bloque de poli(aminoácido) mixto D,L y usos de los mismos.
Patent EC-SP044975-A (EC)
Title: Cristales anhidros que incluyen una sal del ácido málico de una 2-indolinona sustituida con 3-pirrol, metodos de preparación y composiciones que los contienen
Inventor: HAWLEY MICHAEL
IPC: A61P35/02
Filed: 2004-02-10
Abstract: Cristales anhidros de una sal de ácido málico de un compuesto que tiene la estructura donde el cristal es preferentemente ácido málico es ácido L-málico o una sal del ácido málico de N-[2-(dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-oxo-3H-indol-3-iliden)metil]-2,4-dimetil-1H-pirrol-3-carboxamida, y tiene picos de difracción característicos a aproximadamente 13,2 y 24,2 grados dos teta (forma cristalina I) en un patrón de difracción del polvo por rayos X, preferentemente a aproximadamente 13,2, 19,4, 24,2 y 25,5 grados dos teta, o picos de difracción característicos a aproximadamente 3,0 y 27,2 grados dos teta en un patrón de difracción del polvo por rayos X , preferentemente a aproximadamente 13,2, 19,4, 24,2 y 25,5 grados dos teta (forma cristalina II) en un patrón de difracción del polvo por rayos X, preferentemente a aproximadamente 3,0, 12,1, 14,5 y 27,7 grados dos teta; métodos para preparar dichos cristales anhidros; y composición que los comprende.
Patent EC-SP055783-A (EC)
Inventor: WEBER ANN E
IPC: A61K31/445
Filed: 2005-05-06
Abstract: The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Patent EC-SP064643-A (EC)
Inventor: MICANOVIC RADMILA
IPC: C12N15/62
Filed: 2006-06-06
Abstract: The present invention relates to glucagon-like-1 compounds fused to proteins that have the effect of extending the  in vivo  half-life of the peptides. These fusion proteins can be used to treat non-insulin dependent diabetes mellitus as well as a variety of other conditions.
Patent EC-SP088512-A (EC)
Title: Uso de piraclostrobina como asegurador para triticonazol para combatir hongos nocivos
Inventor: STIERL REINHARD
IPC: A01N43/54
Filed: 2008-06-09
Abstract: (1)	Uso de piraclostrobina de la fórmula I 	como asegurador para(2)	triticonazol de la fórmula II o sus sales o aductos para combatir hongos nocivos.Uso de los compuestos I y II en un procedimiento para combatir hongos nocivos con mezclas de los compuestos I y II y el uso de los compuestos I y II para la obtención de tales mezclas, así como productos, que contienen estas mezclas.
Patent FI-20075874-A (FI)
Inventor: LAURONEN MIKA
IPC: G06K/
Filed: 2007-12-04
Abstract: The present invention relates generally to acquisition of data from RFID devices (132-136), such as sensor data. Prior art systems of active RFID devices have a problem of high average power consumption, and therefore, the energy source of the RFID devices needs to be replaced or charged frequently. The present invention provides a new solution wherein the RFID device has a power saving mode in which the receiver of the RFID device has a decreased ability to receive/detect RF signals. The RFID device may include a timer which is functional during the power saving mode, and the receiver of the RFID device will turn into active mode at a point of time based on the time value of the timer. Signal strength of an RF channel is indicated with a receiver, and transmission of data is dependent on the indication of the signal strength.
Patent FI-20116255-A (FI)
Inventor: LOKKINEN MIKA
IPC: E03F5/04
Filed: 2011-12-09
Abstract: The invention discloses a guiding device for guiding a tool. The guiding device is arranged to guide the tool for forming in a structure one or more grooves to receive a wet sealant. Additionally is disclosed an arrangement for forming a groove in a structure, and use of the guiding device and the arrangement for forming a groove in a structure.
Patent FR-1113325-A (FR)
IPC: C22C28/00
Filed: 1954-09-16
Granted: 1956-03-28
Abstract: A semiconducting material, consisting of an alloy composition of aluminium antimonide and gallium antimonide, contains (by weight): .Ga.0,93.-.33,5 per cent .Al.1,44.-.17,65 per cent .Sb.the remainder,.. the weight percentage of Ga plus 2,01 times the weight percentage of Al being equal to 36,4 to 3 significant figures. A particular composition described consists of: Ga 20,5 per cent; Al 7,9 per cent; Sb the remainder.  The conductivity type of the material may be modified by adding zinc antimonide, cadmium antimonide, gallium telluride, gallium selenide or gallium sulphide up to a total of 0,01 atomic per cent.
Patent FR-1601153-A (FR)
Title: Cladding or panels comprising a synthetic - foam core covered with sheet material and inc
IPC: E04C2/24
Filed: 1968-12-27
Granted: 1970-08-10
Abstract: Slabs of synthetic foam covered on one or both faces with a stiffer sheet material (wallpaper, plastic film, aluminium foil, wood veneer, cloth) and pref. having wooden inserts (along the edges) for securing hinges, screws, etc. For insulating and decorating buildings, paths, walls, etc. - lighter than chipboard cored panels.
Patent GB-1050375-A (GB)
IPC: F25D23/02
Abstract: 1,050,375. Refrigerators. COMPAGNIE FRANCAISE THOMPSON-HOUSTON. June 10, 1964 [June 11, 1963], No. 24092/64. Heading F4H. A refrigerator door comprises a panel 4 mounted in a rectangular frame (Fig. 1) having identical side members 2 and identical top and bottom members 3, hinge members 8, 8b being provided at each comer of the frame-so that the door may be hung from either side of a refriger - ator door opening. As shown in Fig. 3, parts 9, 10 and 11 of each side member 2 together with the panel 4 define an inwardly open channel, the parts 8 of the hinge members being mounted in the upper and lower ends of the channel and the remainder of the channel being left open so that the part 9 of each member 2 forms a handle extending over substantially the whole height of the door. The side edges of the panel 4 are engaged by parts 12 13 and 14 of members 2, a door seal 7 is secured to a part 16 of each member 2 and a tongue portion 7a of the seal 7 and the edge 5a of an inner door panel 5 are gripped between parts 17 of members 2 and the panel 4. The hinge members are provided with recesses 8a which receive pivot pins mounted on the desired side of the door opening. The top and bottom members 3 of the frame are identical with the members 2 except in that the parts 9, 10 and 11 are omitted. Insulation 6 is provided between the door panels 4 and 5.
Patent GB-1053168-A (GB)
IPC: F16K15/20
Abstract: 1,053,168. Air cushions. DUNLOP RUBBER CO. Ltd. May 1, 1964 [May 4, 1963], No. 18118/64. Heading A4M. An air cushion 2 having a filling connection 4 is fitted with a screw cap 7 having an inflation valve 9 of known type set in the closure portion 8 of the cap 7 such that the connection nipple 11 does not project beyond the top of the raised collar 12 of the cap 7. A sealing ring 6 is fitted as shown. Loss of the cap 7 is prevented by a chain 15 connecting the valve 9 to a pin 16 located within the cushion.
Patent GB-1225461-A (GB)
IPC: C07D295/088
Filed: 1969-09-17
Abstract: 1,225,461. Piperazine derivatives. BOEHRINGER MANNHEIM G.m.b.H. 17 Sept., 1969 [19 Sept., 1968], No. 45804/69. Heading C2C. Novel piperazine derivatives of the Formula I wherein R 1 , R 2  and R 3 , which may be the same or different, are H, halogen, CF 3 , C 1-3  alkyl or C 1-3  alkoxy, X is a valency bond or -CH 2 -, n is 1 to 8 and m is 2 or 3, and pharmacologically compatible acid addition salts thereof are prepared by reacting the appropriate piperazine compounds with the corresponding haloacetanilides; or by reacting piperazine derivatives of the Formula IV: wherein Y is a reactive ester group with alcohols of the Formula V above; or by reacting reactive derivatives of the appropriate piperazin-4-ylacetic acids with the corresponding anilines. Pharmaceutical compositions, suitable for enteral or parenteral administration and having coronary dilatory activity, contain the above novel piperazine compounds or pharmacologically compatible acid addition salts thereof in admixture with solid or liquid pharmaceutical carriers or diluents.
Patent GB-1225751-A (GB)
IPC: B01D46/10
Filed: 1966-12-30
Abstract: 1,225,751. Laminated filters. D. A. G. MARSHALL. 15 March, 1968 [30 Dec., 1966], No. 58298/66. Heading B5N. [Also in Divisions B1-B2] An air filter, for removing radioactive or chemical contaminants, comprises layers 10, 12, 14 of honeycomb structure, made of resinimpregnated paper with activated carbon granules in each cell, the cells in the different layers being relatively staggered, metal reinforcing grilles 16, 18, 20, 22, and top and bottom layers 24, 26 of demembraned polyurethane foam, whose marginal portions are folded over each other (Fig. 2, not shown), to enclose the edges of the honeycomb layers, and are then sealed to a peripheral frame (32), of gravity cast, glass fibre-reinforced, catalystsetting polyester or epoxy resin (Fig. 3, not shown). In manufacture, grilles 16-22 are heated, dipped into polyethylene powder which forms a liquid coating thereon and pressed with layers 10, 12, 14 interposed, to bond these layers and grilles together.
Patent GB-1225793-A (GB)
IPC: A61M3/00
Filed: 1968-06-04
Abstract: 1,225,793. Syringes. I. SOLOWEY. June 4, 1968 [Jan.22, 1968], No.26539/68. Heading F1R. [Also in Division A5] A syringe comprises a cylindrical barrel 11 containing a plunger 12, the barrel having a constricted opening 14 at one end and at the opposite end a rigidly secured collar through which the stem 23 of the plunger passes, there being attached to the plunger stem a member 27 which is deformable to pass through the collar when the plunger is pushed into the barrel and which abuts the collar and resists deformation when an outward pulling force is inserted on the plunger. The syringe may be used to administer a medicament 19 to a body cavity and, as shown, the barrel is provided with a collar 20 and with a constricted neck 13 having an outlet opening 14, there being a unit 25 on the plunger 12 comprising a flexible disc 27 and a smaller rigid disc 26 which discs are, respectively, larger and smaller than the opening 22 in the collar. In use, on depressing the plunger, the disc 27 flexes Fig.2, (not shown) so that both discs 26 and 27 are able to pass through the opening 22 in the collar, withdrawal of the plunger then being prevented since the rigid disc 26 prevents the reverse flexure of the disc 27. The flexible disc 27 is of a rubber or plastics material and the collar 20, which may have finger grips, is of a rigid plastics material and is secured to the syringe barrel by adhesive or by screwthreads.
Patent GB-1226012-A (GB)
IPC: C01F7/34
Filed: 1968-06-25
Abstract: 1,226,012. Gas chromatography. MITSUBISHI CHEMICAL INDUSTRIES Ltd. 25 June, 1968 [26 June, 1967; 24 July, 1967; 18 Dec., 1967], No. 30284/68. Heading B1L. [Also in Division C1] 0-Alumina produced by treating an aqueous solution of an aluminium salt of a monobasic acid with an aqueous solution of an acid carbonate, and then ageing the resulting alumina hydrate in an aqueous solution at a pH of 4.0-7.5 at between room temperature and 250‹C for at least 2 hours, and subsequently calcining at 1050-1200‹C is used as a filler for gas chromatography columns. The filler is efficient in separating aromatic isomeric mixtures such as o-, m- and p-xylene, as well as in separating sequences of naphthenes, paraffins and olefins. A tailing reducer may be used to impregnate the filler, e.g. silicone oil, paraffin oil, ethylene glycol, dioctyl terephthalae or esters, polyesters, amines or polyamines. A He carrier-gas is used in examples.
Patent GB-1226027-A (GB)
IPC: E02B15/06
Filed: 1968-11-06
Abstract: 1,226,027. Floating barriers. T. MIKKELSEN. 6 Nov., 1968 [6 Nov., 1967], No. 52487/ 68. Heading E1H. A boom comprises floatable flat sections 10 (e.g. of a foamed plastics such as foamed polyurethane) joined together by hinges (e.g. formed of a glass fibre canvas impregnated with a plastics material) to form a foldable zig-zag wall to provide above the water surface a substantially upstanding barrier (e.g. to oil &c. floating on the water) and at least one purse string 15, 16 capable of being drawn to fold the sections, shortening the boom, which if encircling an area of water, reduces that area. The strings 15, 16 may pass through either rings 17 on alternate hinges or holes in each section near the alternate hinge. The rings 17 may be anchored to strips 18 of fabric on the section, and be interconnected by strings 19 to limit the unfolding of the sections. The sections 10 may be ballasted by long lead weights 14 or an enclosed chain. Typical dimensions are given.
Patent GB-1227641-A (GB)
IPC: F02B75/02
Filed: 1969-02-07
Abstract: 1,227,641. Fuel injection engines; combustion chambers. McCULLOH CORP. Feb. 7, 1969 [June 24, 1968], No. 6721/69. Heading F1B. An I. C, engine comprises wall means 40, Fig. 7 moved by a piston and operable to define a series of spaced airstreams flowing between the interior and exterior of a combustion zone, a fuel source operably to define a series of spaced fuel streams which intersect with the airstreams to form burning loci, the piston being operable to move the wall means generally away from the fuel source while the fuel streams are being projected into the burning loci and while the wall means provide paths of limited communication between the combustion zone of the engine in direct communication with the piston. Air drawn into cylinder 3, Fig. 1 through ports 13 is compressed and transferred via conduit 15 into cylinder 4 where it is further compressed and passes via slots 40, into the cumbustion chamber. A fuel pump 20 supplies fuel to injection nozzle 21 and a series of fuel sprays are directed towards the air passing through the slots so that burning is initiated at the intersection zones. The protrusion 24 which may be of stainless steel is retained by a nut and Belleville washers.
Patent GB-1228293-A (GB)
IPC: B22F9/08
Filed: 1969-08-13
Abstract: 1,228,293. Producing metal shot. L. W. BLIEMEISTER. Aug. 13, 1969 [Nov. 4, 1968; May 5, 1969], No.40388/69. Heading C7X. Shot forming apparatus comprises a receptacle 18 for melted metal apertured for gravitational flow of metal therefrom, a stack of sheets of metal in close face-to-face relationship which receive metal from 18 and constitute a feeder assembly, the sheets being perforated to provide a plurality of discharge orifices, and spring clamping means 112 to clamp the sheets together under sufficient pressure to prevent lateral leakage of metal but so as to allow freedom for slippage of the sheets on thermal expansion. Metal from header tank 12 Fig. 1 (not shown) is fed via a conduit and adjustable valve 24 into vessel 18, which is heated by burners 90, and proceeds through holes 114 in the base 54 of trough 18 to space 115 under 54 Fig. 10 and thence through interconnected axially non-aligned holes 116, 118 and 120 in first orifice plate 105, spacer plate 106, and second orifice plate 108 respectively, the whole unit 54 being meanwhile vibrated for easy release of droplets, which issue from orifices 120 and pass through larger openings 122 in shield plate 110, and fall into quenching bath 25 on to inclined interrupter plates 28, and are retrieved by a conveyer belt for subsequent storage. The assembly partly shown in Fig. 10 is readily demountable, and orifice plates 105 and 108 may be changed as required in order to make different sized shot.
Patent GB-1228478-A (GB)
IPC: C25D3/22
Filed: 1968-09-27
Abstract: 1,228,478. Electro-plating with zinc. RUMANIA, MINISTRY OF MACHINE BUILDING INDUSTRY. Sept.27, 1968, No.46103/68. Heading C7B. An alkaline zinc electro-plating bath of improved throwing power contains zincate ions and sodium hexametaphosphate as complexing agent, preferably in a concentration of 30 to 45 g/l. Preferably the bath also contains as a brightener 1 to 5 g/l of furfural, gelatine or a sulphonated lignin-containing solution ("sulphite cellulose waste"), and optionally also an aliphatic aldehyde, aromatic ketone, a thiourea, reaction product of a heterocyclic aldehyde with an aromatic amine or nitrogen, or ammonium molybdate. Reference is also made to the addition of sodium sulphite and wetting agents. Articles of iron, steel, brass or aluminium alloy may be zinc plated from the bath, the articles being hung on a cathode bar oscillated at 1 c/s to agitate the bath. Prior to electro-plating the articles may be electrolytically degreased and given an acid dip and after plating they may be chromated.
Patent GB-1229608-A (GB)
IPC: G02B1/04
Filed: 1968-07-15
Abstract: 1,229,608. Contact lenses. DOW CORNING CORP. July 15, 1968 [Aug. 11, 1967], No.33606/68. Heading G2J. A contact lens is made from an organic elastomer, preferably having a refractive index of 1À4 and an oxygen transmission rate of at least 1 micro-litre per hour per square centimetre through an 0À05 cm thick film. The elastomer may be an ethylene-propylene-tetropolymer, a cis-polyisoprene, a stryrene-butadiene copolymer or a cis-polybutadiene, and may be reinforced by addition of suitable fillers, anti-oxidants, antiozonites, or pigments. A quantative example is given.
Patent GB-1232522-A (GB)
IPC: C14C11/00
Filed: 1969-07-14
Abstract: 1,232,522. Finishing skiver. FARBENFABRIKEN BAYER. A.G. July 14, 1969 [Aug 1, 1968], No.35262/69. Heading C6C. Skiver is finished by bonding to it a polyurethane film which has previously been coated, on that side which faces the skiver, with a layer of flocked fibres, the coating preferably having been applied while the film was still tacky after its formation. Bonding is effected either by the adhesive effect of a paste acting as a binder for the flock, or by use of an adhesive. The flock may be cotton, viscose, a polyamide, a polyester, a polyurethane orpolyacrylonitrile. The polyurethane is obtained by reacting a hydroxy-polyester, hydroxypolyether, hydroxy-polyester-amide, hydroxypolyacetal or hydroxy-polester-urethane with a polyisocyanate.
Patent GB-1233066-A (GB)
IPC: H01H1/08
Filed: 1968-08-19
Abstract: 1,233,066. Mercury wetted contact devices. C. P. CLARE & CO. 19 Aug., 1968 [11 Oct., 1967], No. 39499/68. Heading H1N. A sealed magnetic contact unit of the mercury wetted contact type has its sealed insulating housing 12 supporting, at one end, a pair of spaced fixed contacts 14, 16 and at the other end an armature support 20 on which a contact armature 24 is pivotally mounted with its upper end extending between the fixed contacts. The armature has a " capillary surface " and is welded at 40 on a pin 38 rotatably fitting in holes 36 in a U-shaped bracket 34 secured to the support 20. The fixed contacts are similar to those of Specification 1,105, 923 and the armature 24 has a transverse member 48 at its upper end to prevent mercury splashing and to form mercuring fillets where it joins the armature to distort on impact and limit rebound. Members 24, 34 and 38 form parts of the elongated mercury wettable path between a reservoir pool 28 and the contacts and the mercury serves as a lubricant for the armature pivot. The contacts can be arranged for make-before-break or breakbefore-make action and polarizing magnets (not shown) acting on contact members 14, 16 with a coil surrounding the unit provide a bi-stable relay capable of operation at 600 cycles per second. During manufacture mercury is passed through the hollow support 20 and an opening 26 therein before filling the housing with gas through the same means and sealing the member 20 at 20A.
Patent GB-1234075-A (GB)
IPC: B29C70/02
Filed: 1968-05-10
Abstract: 1,234,075. Bonded fibre article, lap forming. apparatus. COMPAGNIE DE SAINT-GOBAIN. 10 May, 1968 [11 May, 1967; 12 May, 1967; 18 April, 1968], No. 22271/68. Headings D1N and D1R. [Also in Divisions B8 and Cl] A mineral fibre mat is made by moving a stream of mineral, e.g. glass, fibres to a collecting means, causing a sheet of solid particles to flow homogeneously and at a constant rate (over surface 136), projecting the particles of the sheet into the stream of fibres by a gaseous current (issuing from slot 140) to homogeneously distribute the particles in the stream before it reaches the collecting means, spraying a thermosetting binding agent onto the fibres and/or particles before they reach the collecting means, and reducing the volume of the collected mass of fibres whereby the particles are homogeneously distributed therein on setting of the binder. The binder, e.g. phenol formaldehyde resin, can be sprayed onto the particles before they reach the fibre stream. The particles can be perlite, vermiculite, sand, ground glass, pulverised rock or pulverised slag. The particles can be passed along a rectilinear conveyordistributor and down chutes (as shown), or through an annular screw feed conveyordistributor (Figs. 14 and 15), before meeting an annular frusto-conical surface to form the sheet of flowing particles. The fibre-particle stream may pass through an oscillatable duct 144 and be collected on a conveyor subjected to suction.
Patent GB-1238123-A (GB)
IPC: C07D207/456
Filed: 1969-09-26
Abstract: 1,238,123. N-phenyl-maleimides. SUMITOMO CHEMICAL CO. Ltd. 26 Sept., 1969 [9 Oct., 1968], No. 47493/69. Heading C2C. [Also in Division A5] Novel compounds of formula wherein R 1  is a hydrogen or halogen atom or a C 1-4  alkyl, phenyl or halophenyl group, R 2  is a hydrogen or halogen atom or a C 1-4  alkyl group, and X is a halogen atom, provided that when R 1  and R 2  are both halogen atoms, X is not chlorine, are prepared by cyclodehydration of a compound of formula The compounds of the invention have microbiocidal activity (see Division A5).