baber/WOPTO huggingface dataset:
Patent DE-69024918-D1 (DE)
Inventor: HERT MARIUS
IPC: C08L65/00
Filed: 1990-11-07
Granted: 1996-02-29
Abstract: This composition comprises a mixture of 20 to 70 parts by weight of polynorbornene, crosslinked or uncrosslinked, 80 to 30 parts by weight of a polymer based on vinyl chloride and of at least one plasticiser customary for polynorbornene and the polymer based on vinyl chloride in an amount sufficient for reducing the glass-transition temperature of polynorbornene down to the range of rubbers. To prepare the thermoplastic composition comprising crosslinked polynorbornene, a mixture of polynorbornene, a polymer based on vinyl chloride, a plasticiser customary for polynorbornene and the polymer based on vinyl chloride and a crosslinking system is kneaded at a temperature sufficiently high and during a period sufficiently long for crosslinking polynorbornene. Applications: Manufacture of flexible tubes, seals for the construction and automobile industries, protective bellows for the automobile industry, injection-moulded articles, such as solid wheels for the toy industry, and the like.
Patent DE-69028455-D1 (DE)
Inventor: DEKOK PETER T
IPC: B24D11/02
Filed: 1990-01-29
Granted: 1996-10-17
Abstract: An abrasive material is formed by uniformly spacing particles of diamond or other hard, abrasive material, on a carrier embedding the particles in the carrier, and fixing the particles to the carrier with the particles protruding from the carrier to perform the abrasive action. The particles can be distributed by placing them in the openings of a mesh and the mesh is then removed. Since the carrier may be flexible, the carrier can be shaped to conform to substrates of complex shapes. A plurality of carriers having different concentrations can be bonded together to form tools having varying concentrations. <IMAGE>
Patent DE-69030154-D1 (DE)
Inventor: GULICK PAUL E
IPC: G02F1/137
Filed: 1990-11-05
Granted: 1997-04-17
Abstract: A color display is formed by stacking two or more birefringent elements (12-18) that are tuned to provide different spectral characteristics, and operating each of the elements independently.
Patent DE-69032028-D1 (DE)
Inventor: GORELICK ROBERT
IPC: C07K14/16
Filed: 1990-10-31
Granted: 1998-03-12
Abstract: The present invention defines a biological role for the following sequence of amino acids that is found in the nucleocapsid domain of the gag precursor polyproteins of all replication-competent retroviruses: -Cys-X-X-Cys-X-X-X-X-His-X-X-X-X-Cys-, wherein X represents variable amino acids. The invariant residues constitute part of a vital protein structure, at least one of which are found in all retroviruses and which are involved in the selection and packaging of genomic viral RNA into infectious virus particles. Disruption of this structure leads to the formation of virus-like particles which appear to be structurally normal, but which do not contain the normal complement of viral RNA. Therefore, their infectivity is drastically reduced or completely eliminated. The infectivity of any retrovirus, including human retroviruses, and more particularly human immunodeficiency virus (HIV), can be drastically reduced or completely eliminated by generating mutants that lack some or all of the invariant residues required to form the structure. In addition, any means of disrupting the functions of this array will in turn disrupt the viral life cycle. Thus, with the knowledge provided by this invention, chemotherapeutic reagents aimed toward this array may be devised.
Patent DE-69033974-D1 (DE)
Inventor: RACANIELLO VINCENT
IPC: C12N1/11
Filed: 1990-03-09
Granted: 2002-07-25
Abstract: The subject invention provides an isolated nucleic acid molecule which comprises nucleic acid encoding a polypeptide which has the biological activity of a receptor for picornavirus and in addition, provides a purified polypeptide which has this activity. The subject invention also provides a method for inducing the production of a polypeptide which includes the use of expression vectors in a host vector system. Therapeutic compositions comprising purified polypeptides which have the biological activity of a receptor for picornavirus are also provided for as are methods of treating and preventing human poliovirus infection. Further, the subject invention provides a method of producing a transgenic animal expressing human picornavirus. The subject invention provides a method of testing the efficacy of a picornavirus vaccine which comprises administering the vaccine to a transgenic animal described above and determining whether the resulting transgenic animal is protected from infection by human picornavirus. Lastly, a method of testing the virulence of a picornavirus vaccine is provided.
Patent DE-69106432-D1 (DE)
Inventor: D AVOLIO ANTONIO
IPC: H04M1/03
Filed: 1991-02-21
Granted: 1995-02-16
Abstract: To reduce costs and improve piezoceramic transducers, use of a spool with nail-shaped contacts forced thereinto, pressed against the vibrating diaphragm by an elastic O-ring to eliminate solderings and/or spring contacts.
Patent DE-69110239-D1 (DE)
Inventor: PENSABENE SAVERIO F
IPC: H01M50/536
Filed: 1991-09-18
Granted: 1995-07-13
Abstract: An electrode [11] for a rechargeable electrochemical cell including an electrically conductive substrate [13], a layer of an electrochemically active material [15] attached to the substrate, the active material comprising a reducible species of a metal, at least one conductive contact area [12] formed of a metallic form of said metal attached to said substrate, said metallic contact area comprising said reducible species in a converted form. A positive electrode is further provided wherein said active material is nickel hydroxide and said metallic form of said metal is nickel metal. The invention further comprises the method for manufacturing electrodes as described above, featuring use of reducing gas to effect conversion. <IMAGE>
Patent DE-69113015-D1 (DE)
Inventor: MASI ANTONIO
IPC: A47C31/11
Filed: 1991-06-28
Granted: 1995-10-19
Abstract: Seat cover for a front motor vehicle seat, comprising a cover (3) made from a single piece with a part (30) intended to cover the actual seat (1) and a part (40) intended to cover the back (2), in which the part (30) of the cover intended to cover the seat is equipped with sections (31) for covering the sides and the front edge (11) of the seat and which have a lower edge (33) of a length which is shorter than that of the upper edge (34) in order to ensure the stability of the cover against any upward movement, whilst an elastic fabric portion (32), which joins the said panels in pairs, stretches them, and in which the part (40) of the cover intended to cover the back is equipped with two lateral panels (41) for covering the sides (20) and which are extended (42) so that they make it possible to surround the top of the back and are able to be fastened together in this position, although in a detachable manner, by means of "Velcro" strips of a length permitting satisfactory adaptation to backs of different sizes. <IMAGE>
Patent DE-69116098-D1 (DE)
Inventor: TACKETT TIMOTHY NEAL
IPC: G02B6/36
Filed: 1991-10-17
Granted: 1996-02-15
Abstract: A fibre optic connector comprises a fibre (10) having a planar end surface formed by hot plate melting. A terminal fitting surrounds the fibre (10) and has a terminal face (24) coplanar with the fibre end surface. A reservoir groove (28) is formed in the terminal face (24) surrounding the exit aperture (22) and is isolated therefrom by a portion (30) of the terminal face. The groove (28) is preferably dimensioned to completely receive subsurface the excess reflowed fibre material resulting from the hot plate melting. The exit aperture (22) is circular and the groove (28) has a coaxial inner diameter only sufficiently larger than the diameter of the exit aperture (22) to assure isolation of the groove (28) from the exit aperture (22). <IMAGE>
Patent DE-69120342-D1 (DE)
Inventor: STEFANO JAMES E
IPC: C12Q1/68
Filed: 1991-04-25
Granted: 1996-07-25
Abstract: Mutant forms of midivariant RNA are disclosed which are replicated efficiently by the enzyme Q beta  replicase in the presence of an agent(s) which is useful for the real time, quantitative detection of the accumulating RNA products. This agent(s) also suppresses the replication of non-mutant wild type midivariant RNA. The mutant MDV RNAs, when modified by the addition of specific probe sequences, retain their replication properties in the presence of the detection agent. This method allows the replication to be monitored using a real time mode thereby providing a reliable method for monitoring the kinetics of the reaction, and determining the initial level of amplified RNA.
Patent DE-69129083-D1 (DE)
Inventor: GLASS MITCHELL
IPC: A61P11/00
Filed: 1991-05-17
Granted: 1998-04-23
Abstract: There is provided a novel therapeutic agent for use in the prevention or treatment of adult respiratory distress syndrome and for use in the manufacture of a medicament for the prevention or treatment of adult respiratory distress syndrome, as well as a method of prevention or treatment of adult respiratory distress syndrome with the therapeutic agent and a method of treatment of cystic fibrosis with the therapeutic agent in combination with one or more other agents indicated for the treatment of adult respiratory distress syndrome.
Patent DE-69132943-D1 (DE)
Inventor: TAPPER ROBERT
IPC: A61N1/32
Filed: 1991-11-04
Granted: 2002-04-04
Abstract: A method and apparatus for applying iontophoretic treatment to a biological subject wherein electrical treatment current between a pair of electrodes is periodically reversed at very low frequencies, substantially in the range of approximately 0.0027 Hz to approximately 10 Hz, to mitigate tissue damage, enable long term dosimetry with single and multiple drugs of any polarity and at higher concentrations, and eliminate the need for buffering agents and the like, all in a relatively simple, economical and compact physical packaging configuration. The system delivers treatment substances with large and/or small molecular size and weight and can be adjusted to control pH at the delivery site. A method of lowering resistance and enhancing permeability at the delivery site, as well as increasing drug concentrations and delivery rates. <IMAGE>
Patent DE-69206102-D1 (DE)
Inventor: JINDRICH JINDRICH
IPC: C07F9/6561
Filed: 1992-05-19
Granted: 1995-12-21
Abstract: PCT No. PCT/CS92/00013 Sec. 371 Date Jan. 13, 1993 Sec. 102(e) Date Jan. 13, 1993 PCT Filed May 19, 1992 PCT Pub. No. WO92/20691 PCT Pub. Date Nov. 26, 1992.The invention relates to new compounds, di(2-propyl) esters of (R)-, (S)- and (RS)-1-fluoro-2-phosphonomethoxy-3-p-toluenesulfonyloxypropane and the method of producing them. The compounds can be used with advantage in the preparation of N-(3-fluoro-2-phosphonomethoxypropyl) derivatives of heterocyclic purine and pyrimidine bases that have antiviral activity.
Patent DE-69207429-D1 (DE)
Inventor: GODEK DENNIS
IPC: C07D213/75
Filed: 1992-11-24
Granted: 1996-02-15
Abstract: Novel processes are disclosed for the preparation and resolution of substituted piperidines of the formula    <IMAGE>  (I)  wherein R1 and R2 are defined as below, and related compounds, as well as novel intermediates used in such processes.
Patent DE-69207526-D1 (DE)
Inventor: MARYANOFF CYNTHIA A
IPC: A61K31/135
Filed: 1992-09-11
Granted: 1996-02-22
Abstract: This invention relates to a tramadol N-oxide material, enantiomers and compositions thereof and their use. The tramadol N-oxide material and compositions thereof are pharmacologically useful in treating pain, diarrhea and tussive conditions. The tramadol N-oxide is also subject to less side-effects as compared to pure opiate based compositions, such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, the tramadol N-oxide material when administered orally exhibits analgesia for a longer duration than an equi-analgesic amount of tramadol.
Patent DE-69228939-D1 (DE)
Inventor: LONG DONALD
IPC: G06F11/00
Filed: 1992-10-13
Granted: 1999-05-20
Abstract: A computer system comprises a storage device comprising a plurality of locations for storing data and having a defined audit partition region comprising one or more of said locations and processing circuitry for detecting access requests to alter data on respective sets of one or more of locations of the storage device. Responsive to each access request, the processing circuitry stores data from said respective set of locations in the audit partition region prior to performing the access request, such that a sequence of data transfers from the storage device is stored in the audit partition region in a known order. Responsive to a user request, data is restored from the sequence of data transfers in the audit partition region to the respective set of locations on the storage device to return the storage device to a previous state.
Patent DE-69307875-D1 (DE)
Inventor: MACOR JOHN
IPC: C07D401/06
Filed: 1993-03-04
Granted: 1997-03-13
Abstract: PCT No. PCT/US93/01807 Sec. 371 Date Sep. 14, 1994 Sec. 102(e) Date Sep. 14, 1994 PCT Filed Mar. 4, 1993 PCT Pub. No. WO93/21180 PCT Pub. Date Oct. 25, 1993.    <IMAGE>  (I)  Compounds of formula (I) where n is 0, 1, or 2; m is 0 or 1; Y and W are each an amino acid residue; R1 is hydrogen, C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, aryl, C1-C3 alkylaryl, or C1-C3 alkylheteroaryl, and -(CH2)pR3; R2 is CF3, C1-C6 alkyl, aryl, C1-C3 alkylaryl, and -OR5; R3 is cyano, trifluoromethyl, or -OR4; R4 is hydrogen, C1-C6 alkyl, C1-C3 alkylaryl, or aryl; R5 is C1-C6 alkyl, C1-C3 alkylaryl, or aryl; R6 is hydrogen, -OR7, or -NHCOR7; R7 is hydrogen, C1 to C6 alkyl, aryl or C1 to C3 alkyl-aryl; p is 1, 2, or 3; and the above aryl groups and the aryl moieties of the above alkyl-aryl groups are independently selected from phenyl and substituted phenyl, wherein said substituted phenyl may be substituted with one to three groups selected from C1 to C4 alkyl, halogen, hydroxy, cyano, carboxamide, nitro, and C1 to C4 alkoxy and the pharmaceutically acceptable salts thereof. These compounds are useful in treating migraine and other disorders. These compound are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and may be used in the treatment of depression, anxiety, eating disorders, obesity, drug abuse, cluster headache, migraine, pain, and chronic paroxysmal hemicrania and headache associated with vascular disorders, and other disorders arising from deficient serotonergic neurotransmission. The compounds can also be used as centrally acting antihypertensives and vasodilators.
Patent DE-69311040-D1 (DE)
Inventor: GRENIER MAURICE
IPC: F25J3/00
Filed: 1993-09-08
Granted: 1997-07-03
Abstract: In this installation, the treatment column (1) is insulated by a vacuum casing (15), while the heat exchange line (3) is insulated by a cold box (19) at atmospheric pressure containing a solid insulant, in particular in particle form. <IMAGE>
Patent DE-69311786-D1 (DE)
Inventor: WILLIAMS MARTIN MARION
IPC: C09D7/63
Filed: 1993-10-26
Granted: 1997-07-31
Abstract: The invention is directed to an aqueous release coating comprising a polymer and an aqueous solution or dispersion of an alkylester trimethyl quaternary ammonium salt or tallow trimethyl quaternary ammonium salt. The invention is also directed to use of a layer of the aqueous release coating composition on a layer of pressure sensitive adhesive on a backing layer. The aqueous release coating layer permits the pressure sensitive adhesive layer to be easily separated from the backing layer, even after storage for long durations and under extreme temperature and humidity conditions. The aqueous release coating does not migrate into the pressure sensitive adhesive layer and interfere with the adhesive properties of the pressure sensitive adhesive.
Patent DE-69317682-D1 (DE)
Inventor: GENNARI JEAN MARIE LES JARDINS
IPC: A61B17/70
Filed: 1993-01-21
Granted: 1998-05-07
Abstract: The prosthetic assembly comprises an element (1) having a part (1b) capable of being fixed at the level of the region of the sacrum, and a part (1a) receiving at least one added means (2) for its attachment at the level of the lumbar region, the said means (2) being designed to receive a connection member (3) capable of receiving a coupling rod (4) for joining, with a capacity for adjustment, at least one other element. <IMAGE>
Patent DE-69331194-D1 (DE)
Inventor: CARTER J
IPC: C12N15/864
Filed: 1993-06-02
Granted: 2002-01-03
Abstract: Described herein are constructions of recombinant DNA comprising modified adeno-associated virus (AAV) DNA sequences capable of functioning as a eukaryotic expression vector for expressing foreign DNA sequences using a novel transcription promoter comprising the termini of AAV DNA. It is shown that expression of a test reporter gene can be obtained from this vector in mammalian cells. It is further shown that this combination of vector and promoter can be used to introduce and express a human gene and correct a genetic defect in human cells resulting from malfunction of the mutant endogenous gene. Further, the vector can be used to correct the genetic defect by expressing a modified version of the human gene consisting of a fusion of part of the said gene and a synthetic sequence contained in the vector. <IMAGE>
Patent DE-69333050-D1 (DE)
Inventor: LACKIE J
IPC: C12Q1/68
Filed: 1993-07-23
Granted: 2003-07-24
Abstract: A system for assaying a fluid sample, typically employing a fluorescent tag, the system comprising a lens capable of focussing both excitation and fluorescent radiation, a fluid-flow conducting conduit being provided in the lens extending transversely of the optical axis of and through the focal region of the latter. One or more mechanical screens are disposed adjacent to the focal region in the conduit to arrest passage of beads as a function of bead diameter. The beads, precoated with at least a moiety of a ligand/conjugate complex, e.g. a specific-binding ligand, are preferably substantially transparent to both the excitation and fluorescent radiation.
Patent DE-69403963-D1 (DE)
Inventor: YANG Bingwei
IPC: C07H17/00
Filed: 1994-03-14
Granted: 1997-07-31
Abstract: PCT No. PCT/US94/02547 Sec. 371 Date Nov. 13, 1995 Sec. 102(e) Date Nov. 13, 1995 PCT Filed Mar. 14, 1994 PCT Pub. No. WO94/26758 PCT Pub. Date Nov. 24, 1994A compound having formula (III). Also, a process of making azithromycin comprising reducing the compound of formula (III) and N-methylating the reduced product.
Patent DE-69408467-D1 (DE)
Inventor: BRILMAN GERRIT
IPC: B65D17/353
Filed: 1994-11-01
Granted: 1998-03-12
Abstract: The invention relates to a container (1), for instance for a liquid, with a body (2) and an end wall (3) which is provided with a tiltable tab (4) for tilting in the end wall to form an opening (5), wherein the tiltable tab (4) is provided with a tab passage (8) such that in the tilted position the tiltable tab (4) bounds the opening (5) in the end wall (3) and connects with the tab passage (8) onto the opening, and that a tiltable tab portion (4) forms a pouring element (13) which extends at least as far as an end wall edge, and to an end wall (3) for a container body with a tiltable tab (4).
Patent DE-69429261-D1 (DE)
Inventor: BAATH B
IPC: G01N22/00
Filed: 1994-02-03
Granted: 2002-01-10
Abstract: A measuring technique and method are provided to simultaneously determine the molecular density of several molecular species and the temperature within a closed process room in a melting or combustion process. In such processes in the industry, e.g. in metallurgic process industry, it is important to determine the temperature and the contents within the gas or flame without physically connect to or disturb the process. This has shown to raise large problems especially at high temperatures. The radio signal over a frequency band is measured on the outside of the process room through a window in the mantel covering as a function of frequency and registered on a computer as a radio spectrum. The system is calibrated by using a known signal transmitted through the process room. The spectral lines are identified by their frequency from a database. The temperature is determined from several lines of the same molecular specie and the molecular densities are determined from the intensities of the lines. The method is suitable to determine vibrational and rotational excitation of molecular species in the radio wavelength range of 30 mu m to 500 m. The densities of molecular species and the temperature can be imaged in three dimensions inside the process room or exhaust channel if interferometers are used for simultaneous two dimensional imaging from several azimuth directions.
Patent DE-69429894-D1 (DE)
Inventor: HARVEY WILSON
IPC: A61L27/00
Filed: 1994-07-27
Granted: 2002-03-28
Abstract: A composite surgical material comprising a collagen matrix reinforced by a layer of a synthetic bioabsorbable material such as polylactide/polyglycolide or oxidised regenerated cellulose, and wherein oil droplets are dispersed in the collagen matrix. The oil droplets comprise 1% to 75% of the weight of the composite and result in improved leak-proofing of the composite. The composite, in the form of a sheet or a tube, is especially useful as a temporary, fully bioabsorbable prosthesis, for membranes or blood vessels where a highly leak-proof prosthesis is required. The invention also provides a method of making a composite surgical material comprising the steps of: providing a layer of a synthetic bioabsorbable material; providing a dispersion of collagen in an oil-in-water emulsion; coating at least one face of the layer of synthetic bioabsorbable material with the said dispersion; and drying the composite material thus obtained. <IMAGE>
Patent DE-69501513-D1 (DE)
Inventor: PHILIPPE MICHEL
IPC: A61Q1/12
Filed: 1995-03-01
Granted: 1998-03-05
Abstract: Cosmetics or pharmaceutical compsn. contains one or more carbamate esters of formula R1CHR2-CH2-O-CO-NR3-A (I) as hydrating agent. R1 = 4-18C alkyl or alkenyl; R2 = 2-16C alkyl or alkenyl; R3 = H or 1-6C alkyl; A = a nonionic hydrophilic gp. Pref. A = (CH2)n(CHOH)mZ; m = 0-5; Z = 1-4C mono- or poly-hydroxy-alkyl.
Patent DE-69504345-D1 (DE)
Inventor: CHEVASSUS MICHEL
IPC: G09F11/30
Filed: 1995-06-22
Granted: 1998-10-01
Abstract: A module for storing, selecting and displaying posters, in particular during sporting events, in urban environments and for point-of-sale advertising, including a frame (10) with a housing (11) and a transparent front wall (20), provided with a rotary assembly (40) consisting of two shafts (54, 56) rotated by a sequential motor (58), one shaft (54) being positioned at the top of the frame while the other (56) is at the bottom thereof, pulleys (60) attached to said shafts with poster moving belts (62) stretched therebetween, separate gripping members (42) secured to said belts, a magazine (44) for storing separate posters that each have gripping tabs (138) with a hole (140), such that said posters are parallel to the transparent front wall, an assembly (46) for selecting one of the stored posters, an assembly (48) for guiding the selected poster, and a member (50) for retaining the unselected posters. Said module is useful for displaying posters, in particular during sporting events, in urban environments and for point-of-sale advertising.