baber/WOPTO huggingface dataset:
Patent NZ-584008-A (NZ)
Title: Accelerated reduction of organic substances with boranes
Inventor: BURKHARDT ELIZABETH
IPC: C07C209/50
Filed: 2008-09-18
Abstract: A process for the accelerated reduction of organic ester substrates by reacting with an amine borane, sulfide borane or ether borane complex as a borane source in the presence of organic accelerator compounds containing both Lewis acidic and Lewis basic sites in their structure, of which the Lewis acidic site can coordinate with the carbonyl group of the substrate and the Lewis basic site can coordinate with the borane wherein the organic accelerator compound contains a structural element of the formula N-B or is an oxazaborolidine or cyclic compound containing a structural element of the formula N-B-O where N- and O- are connected by a carbon chain or is derived from secondary amino alcohol via reaction with boranes or borates and wherein the esters are reduced to give alcohols.
Patent NZ-585500-A (NZ)
Title: Antibodies which bind to an epitope in the extracellular domain of the matrix 2 ectodomain polypeptide of an influenza virus
Inventor: GRANDEA ANDRES G
IPC: A61K39/395
Filed: 2008-11-12
Abstract: Disclosed is isolated fully human monoclonal antibody, wherein said monoclonal antibody has the following characteristics: (a) specifically binds to a non-linear epitope in the ectodomain (M2e) of the matrix 2 (M2) tetrameric protein of an influenza virus; (b) specifically binds to a non-linear epitope of influenza A on infected cells; and (c) specifically binds to a non-linear epitope of the influenza A virus, wherein said epitope includes the amino acid sequence SLLTEV (SEQ ID NO: 42); and wherein the antibody specifically binds to the non-linear epitope with an affinity constant Ka of greater than or equal to 104 M-1 .
Patent NZ-586389-A (NZ)
Title: Dishwasher with rinse aid fluid heated to identical temperature in at least two washing programs.
Inventor: ROSENBAUER MICHAEL
IPC: A47L15/46
Filed: 2009-01-14
Abstract: 586389 A dishwasher is disclosed with two washing programs. Each of the washing programs has at least one washing step (4) and one rinse aid step (6). The dishwasher is adapted to heat the rinse aid fluid in the rinse aid step (6) in each program to a substantially identical maximum temperature of at least 55ºC. The dishwasher is further adapted to limit a washing liquid temperature in a low temperature washing step (4) of one of the programs to approximately 45ºC.
Patent NZ-586805-A (NZ)
Title: Wind-propelled vehicle with a soft wing sail made of three independent panels and having an airfoil shape
Inventor: GONEN ILAN
IPC: B63B15/00
Filed: 2008-09-18
Abstract: Disclosed is a wind-propelled vehicle with a soft wing sail (20). The sail has a rotating mast (10) vertically mounted on a wind-propelled vehicle. Three independently mounted sail panels define the skin of the sail, a front side panel (24) and a pair of side panels (25, 26). Spreaders (31a, 31b) extend transversely of the mast, imparting to them an airfoil shape with leading and trailing edges fore and aft of the mast. Two vertical tracks (41, 42) are secured to both sides of the mast top and the outer ends of each spreader. Sliders are secured to the sail panels, slidable in the tracks, permitting hoisting and reefing the sail panels along the tracks. A boom (60) is pivotally coupled to the mast and a ram secured to the lower spreader and to the boom, the leading and trailing edges defining one wing sail unit, trimming the airfoil shape. An outhaul line pulls clews (27, 28) of both trailing edges together through a block, evening tension rearwardly of the trailing edge clews and permitting the clews to slide along the boom when the airfoil shape is changed.
Patent NZ-591005-A (NZ)
Title: Cable tie with additional portion for re-used strap loop
Inventor: WATSON ROBERT BAIRD
IPC: B65D63/16
Filed: 2009-07-06
Abstract: A cable tie has a conventional cable tie 30 with an elongate strap 36 that has a fastening end 42 to be received in fastening opening 38. The tie also has a further portion 10 having blind locking opening 12 and through fastening opening 14 so as to accommodate an elongate member 32 which is typically re-used strap from over-length cable tie strap.
Patent NZ-595675-A (NZ)
Title: Formulation of microcapsules comprising a dispersed solid chemical
Inventor: MULQUEEN PATRICK JOSEPH
IPC: A01N25/04
Filed: 2006-12-22
Abstract: ABSTRACT - 595675 Disclosed herein is a product comprising microcapsules which themselves comprise: (a) a polymeric shell; and (b) a core which comprises (i) an agrochemical which is a solid at ambient temperature, dispersed in a polymer matrix (which may be polyurea, a polyamide or a polyurethane or a mixture thereof), wherein said agrochemical has a water-solubility in the range of 0.1 to 100 g/l at 20 ?C, and where the matrix has been formed via an interfacial polymerisation of an oil-in-water emulsion, (wherein the agrochemical is a herbicides, fungicides, insecticides, rodenticides, molluscicides and plant growth regulators which may be selected from acetamiprid, clothianidin, imidacloprid, thiacloprid or thiamethoxam, and (ii) a water-immiscible liquid characterised in that the matrix is distributed non-continuously throughout the water-immiscible liquid which may be selected from xylenes or naphthalenes, e.g. Solvesso ® 200; aliphatic organic compounds such as alkyl esters, e.g. Exxate® 700 - Exxate® 1000, Prifer® 6813; paraffinic compounds, e.g. the Norpar® & Isopar® ranges of solvents; alkyl phthalates, such as diethyl phthalate, dibutylphthalate and dioctylphthalate; alcohols, such as isopropyl alcohol; ketones, such as acetophenone and cyclohexanone; mineral oils, e.g. Cropspray® 7N or 11N; vegetable or seed oils, such as rapeseed oil; and alkylated seed oils.
Patent NZ-596820-A (NZ)
Title: Trans-4-[[(5s)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl] (2-methyl-2h-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1h-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid
Inventor: CHEN XINCHAO
IPC: A61K31/55
Filed: 2010-06-28
Abstract: Compound of formula I having the chemical name trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl] (2-methyl-2H-tetrazol- 5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]- cyclohexanecarboxylic acid also refered to as BCCA, as a free acid or a pharmaceutically acceptable salt thereof, hydrate, and hydrate in crystalline form; pharmaceutical formulations; and methods of use are disclosed, including in the manufacture of a medicament for use in the treatment of cardiovascular disease. Also disclosed are intermediates of formula II and formula III
Patent NZ-599522-A (NZ)
Title: Point-of-care fluidic systems and uses thereof
Inventor: HOLMES ELIZABETH A
IPC: A61B5/00
Filed: 2006-03-24
Abstract: 599522 Disclosed is a system for detecting an analyte in a bodily fluid from a subject and employing two-way communication between a test device and an external device. The test device is comprised of a sample collection unit, an assay assembly and an identifier configured to provide the identity of the device. The sample collection unit is configured for collecting a sample of bodily fluid suspected to contain the analyte. The assay assembly contains reactants that react with the sample of bodily fluid based on a protocol received from an external device to yield a detectable signal indicative of the presence and/or concentration of the analyte. The external device is configured to receive information about the identifier from the test device, select the protocol based on the identifier and transmit the protocol to the external device. The external device is also configured to receive information regarding the signal and calculate the analyte concentration in the sample of bodily fluid using the information regarding the signal.
Patent NZ-603421-A (NZ)
Title: Blue colorant derived from genipa americana fruit
Inventor: ECHEVERRI LOPEZ LUIS FERNANDO
IPC: C09B61/00
Filed: 2009-10-01
Abstract: Disclosed is a method of manufacturing a pH stable blue colorant comprising: A. Obtaining raw liquid juice from a Genipa americana fruit; B. Mixing the raw liquid juice with glycine; C. Warming up the raw liquid juice mixed with glycine for a determined period of time; the method may further comprise the steps of: D. Mixing starch with the previously warmed up mix of the raw liquid juice-glycine, to form a raw liquid juiceglycine-starch mix; and E. Dehydrating the raw liquid juice-glycine-starch mix, wherein the dehydrating comprises injectcosmetic producting the raw liquid juice-glycine-starch mix into a heated chamber with an atomizer; wherein the atomizer has the effect of converting the raw liquid juice-glycine-starch mix into small liquid droplets, wherein the chamber heat vaporizes water from said droplets, wherein vaporizing the water from said droplets results in low density particles and high density particles, wherein the high density particles precipitate to the chamber bottom and wherein the low density particles are aspirated with a vacuum, and wherein the aspirated low density particles form dried colorant powder. This pH stable blue colorant is suitable for use in food products, pharmaceutical products, cosmetic products and textile products.
Patent NZ-604302-A (NZ)
Title: Tetrahydro-pyrido-pyrimidine derivatives
Inventor: COOKE NIGEL GRAHAM
IPC: A61P29/00
Filed: 2011-07-06
Abstract: The disclosure relates to substituted tetrahydro-pyrido-pyrimidine derivatives of the formula (I), wherein the variables Y, R1, R2 and m are as defined in the specification. These compounds inhibit the activity or function of the phosphoinositide 3’ OH kinase (PI3K) enzymes and are suitable for the treatment of a disorder or disease selected from rheumatoid arthritis (RA), pemphigus vulgaris (PV), idiopathic thrombocytopenia purpura (ITP), thrombotic thrombocytopenic purpura (TTP), autoimmune hemolytic anemia (AIHA), acquired hemophilia type A (AHA), systemic lupus erythematosus (SLE), multiple sclerosis (MS), myasthenia gravis (MG), Sjogren’s syndrome (SS), ANCA-associated vasculitides, cryoglobulinemia, chronic autoimmune urticaria (CAU), allergy (atopic dermatitis, contact dermatitis, allergic rhinitis), goodpasture’s syndrome, transplant rejection and cancers of haematopoietic origin.
Patent NZ-605449-A (NZ)
Title: Anti-neuropilin antibodies and methods of use
Inventor: SCHMIDT MAIKE
IPC: C07K16/28
Filed: 2011-07-08
Abstract: Disclosed is an isolated antibody that binds to neuropilin-1 (NRP1), wherein the antibody comprises the CDRs/heavy and light chains of the sequences as defined in the specification. Also disclosed is its use in detecting the presence of NRP1 in a biological sample.
Patent NZ-610465-A (NZ)
Title: Clevidipine emulsion formulations containing antimicrobial agents
Inventor: MOTHERAM RAJESHWAR
IPC: C07D211/90
Filed: 2011-10-10
Abstract: Disclosed is a pharmaceutical emulsion formulation comprising: (a) clevidipine, or a pharmaceutically acceptable salt or ester thereof, present at about 0.01 to about 1.0% w/v; (b) an antimicrobial agent, EDTA, present at about 0.001 to about 1.5% w/v; (c) a lipid preferably present at about 2 to about 30% w/v; (d) an emulsifier, preferably present at about 0.2 to about 2.0% w/v; (e) a tonicity modifier, preferably present at about 2 to about 3% w/v; and (f) water. In a preferred pharmaceutical formulation comprises: (a) clevidipine butyrate, present at about 0.01 to about 1% w/v; (b) EDTA, present at about 0.001 to about 0.1% w/v; (c) soybean oil, present at about 4 to about 30% w/v; (d) purified egg yolk phospholipids, present at about 0.2 to about 2% w/v; (e) glycerin, present at about 2 to about 3% w/v; and (f) water up to 100%.
Patent NZ-618389-A (NZ)
Title: Orally administrable compositions comprising avocado/soybean unsaponifiables and lipoic acid and methods of administration
Inventor: FRONDOZA CARMELITA
IPC: C07D339/04
Filed: 2012-05-16
Abstract: The disclosure relates to an orally administrable composition comprising avocado/soybean unsaponifiables and lipoic acid (abstract figure) or derivatives thereof. The composition may include 5-[1,2]-dithiolan-3-yl-pentanoic acid 3-(5-[1,2]-dithiolan-3-yl-pentanoyloxy)-propyl ester; 5-[1,2]-dithiolan-3-ylpentanoic acid 3-(5-[1,2]-dithiolan-3-yl-pentanoylamino)-propyl-amide; coumarinlipoic acid conjugates; 5-[1,2]dithiolan-3-yl-pentanoic acid [1-(4-fluoro-benzyl)-1H-indole-5-yl]-amide; N-lactobionyl-Ne-(5-[1,2]-dithiolan-3-yl-penoyl)-L-lysinyl-1H,1H,2H-perfluorooctylamide; 1,2-diselenolane-3-pentanoic acid; and 1,2-dithiolane derivatives of lipoic acid containing catechol moieties linked through heteroaromatic rings. The disclosure also relates to the use of these compositions in preventing, treating, repairing, protecting, or reducing damage to connective tissues or reducing symptoms associated with damage to connective tissue and reducing levels of one or more inflammatory mediators in connective tissue.
Patent NZ-620801-A (NZ)
Title: Movement joint
Inventor: KEEN ANDREW
IPC: E04B5/36
Filed: 2012-08-31
Abstract: A free movement, arris protection, construction joint (1 - Fig 1) is disclosed. The joint has a pair of arris protection members (2,3 - Fig 3) formed complementarily from strips of sheet with a continuous trapezium wave form. A divider one (2) of the members is typically 100mm deep for a nominal 0.1m deep slab. The other one (3 - Fig 3) is typically 50mm deep. The members are of steel plate. The wave form is comprised of flanges (4,5) extending in the length of the joint and of webs (6) angled to the flanges and the length of the joint. The flanges (4,5) are spaced on opposite sides of a mid-plane of the joint. The members (2,3) are bolted together with frangible nylon bolts (8 - Fig 1), with their top (in use) edges flush. Welded to the outer ones of the flanges are L strips (9) having apertures (10) in their flats extending from the flanges for anchoring the joint to its slabs. Beneath the anchor members, extending out from every other flat (5) of the deep divider one (2) of the protection members are load transfer dowels (14 - Fig 1), with sleeves (15 - Fig 1) on their extent across the mid-plane and beyond. In use, concrete is cast with a horizontally castellated edge, castellations at positions (16) being bounded by the divider member (2). Complementary castellations on the other side of the joint at the positions interdigitate with the first castellations. The castellations extend to the full depth of the slabs and can be expected to have a long life.
Patent NZ-623851-A (NZ)
Title: Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and new intermediates
Inventor: BARTELS BJOERN
IPC: C07D207/333
Filed: 2012-11-08
Abstract: The disclosure relates to the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives of formula I. The proline derivatives of the formula I are preferential inhibitors of the cysteine protease Cathepsin S and may have usein the treatment of metabolic diseases like diabetes, atherosclerosis, abdominal aortic aneurysm, peripheral arterial disease and diabetic nephropathy. The disclosure also relates to intermediates of this process.
Patent NZ-630488-A (NZ)
Title: Piperidine derivatives for gpr119 agonist
Inventor: LEE CHANGSIK
IPC: C07D401/14
Filed: 2013-06-11
Abstract: Disclosed herein are piperidine derivatives of formula I where the variables are as defined herein, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compounds; and pharmaceutical compositions comprising the compound. The piperidine derivatives of formula I are GPR119 agonists and can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders. Specific examples of the compounds of formula I include (S)-1-(2-fluoro-4-(5-((1-(2-fluoro-2-methylpropyl)piperidin-4-yl)methoxy)pyridin-2-yl)benzoyl)pyrrolidine-2-carboxamide and (S)-1-(2’-cyano-3-fluoro-4’-((1-(2-fluoro-2-methylpropyl)piperidin-4-yl)methoxy)biphenylcarbonyl)pyrrolidine-2-carboxamide.
Patent NZ-704197-A (NZ)
Title: Aromatization of coffee
Inventor: VAN LOON-POST ANGENITA DOROTHEA
IPC: A23F5/46
Filed: 2013-06-28
Abstract: Disclosed is a method of aromatizing coffee beans. The beans can be green or roasted, including ground beans, and are allowed to stand together with an aroma generating substance for an effective standing time before removing said substance. The aroma generating substance preferably is a dry and solid natural substance, such as a cinnamon or vanilla stick, in whole or ground form. The invention also pertains to packages comprising both roasted coffee beans and an aroma generating substance present in a removable way.
Patent NZ-706739-A (NZ)
Title: Substituted benzene compounds
Inventor: KUNTZ KEVIN
IPC: C07D213/50
Filed: 2013-10-15
Abstract: The present invention relates to substituted benzene compounds comprising compounds of Formula II: (II) and compounds of Formula III: (III) and compounds of Formula VI: (VI) and compounds of Formula VII: (VII) Such compounds may be useful as EZH2 inhibitors. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
Patent NZ-706764-A (NZ)
Title: Process for the preparation of voriconazole and analogues thereof
Inventor: BURRELL ADAM JAMES MUSGRAVE
IPC: C07D403/06
Filed: 2013-10-08
Abstract: The present invention provides a process for preparing a compound of formula: (Formula XI and XII) (XI) (XII) wherein X, Y, Z, A, B and E are as defined herein, by reacting a compound of formula: (Formula XIII) (XIII) with a compound of formula: (Formula XIV and XV) (XIV) (XV) respectively, in the presence of a transition metal catalyst, a ligand suitable for use with 15 the catalyst and a reducing agent. The invention also provides novel intermediates.
Patent NZ-711789-A (NZ)
Title: A device and method for using a magnetic clutch in bldc motors
Inventor: MOSTOVOY ALEXANDER
IPC: H02K7/11
Filed: 2014-03-13
Abstract: There is disclosed an apparatus for coupling mechanical power between the rotor of a Brushless DC Motor and an external mechanical load. In at least one embodiment, the apparatus comprises: two concentric rings including a rotor-constituting inner ring and an outer ring; an equal number of circumferentially spaced magnets connected to each of the inner ring and the outer ring; each couple of facing magnets of opposite magnetic polarity. One magnet is placed on the inner ring, and its facing magnet is placed on the outer ring. A plurality of circumferentially spaced and stationary air-core solenoids, which, when energized, generate an electromagnetic field producing a torque on a magnetic field of the inner ring magnet passing through their interior to cause the inner ring to rotate, wherein when the inner ring rotates, the outer ring rotates as well by magnetic forces between each couple of facing magnets; and connectors which connect the outer ring to a mechanical load. Configurations of the latter nature serve to, at least in part, address identified deficiencies with existing prior art arrangements, eg. energy losses and wear caused by friction resulting in the need for increased maintenance services and/or frequent replacement of parts.
Patent NZ-725469-A (NZ)
Title: Apparatus for controlling fluid flow
Inventor: KAMEN DEAN
IPC: A61M5/168
Filed: 2012-12-21
Abstract: A method for estimating volume of drop in intravenous drip chamber using pixels contained in the drop’s outline is described. The method determines a relevant subset of pixels in the image of the drop in the drip chamber by assessing which pixels represent the edge of the drop and whether the edge of the drop is contiguous with a baseline (215) determined within the drip chamber. The pixels within the outline are counted to indicate the area in the image, and the area is rotated and thus integrated to determine the volume.
Patent NZ-734220-A (NZ)
Title: Methods of treating conditions related to the s1p1 receptor
Inventor: SHANAHAN WILLIAM R
IPC: A61P29/00
Filed: 2016-01-06
Abstract: Provided are methods of treatment of a sphingosine 1-phosphate subtype 1 (S1P1) receptor-associated disorder comprising prescribing and/or administering to an individual in need thereof a standard dose of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid (Compound 1), or a pharmaceutically acceptable salt, hydrate, or solvate thereof, in an amount equivalent to about 1.5 to about 2.5 mg of Compound 1, for example, a disease or disorder mediated by lymphocytes, an autoimmune disease or disorder, an inflammatory disease or disorder, ankylosing spondylitis, biliary cirrhosis, cancer, psoriasis, psoriatic arthritis, rheumatoid arthritis, Crohn’s disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, inflammatory bowel disease, ulcerative colitis, type I diabetes, hypertensive nephropathy, glomerulosclerosis, myocardial ischemia-reperfusion injury, and acne.
Patent NZ-734361-A (NZ)
Title: Water-tight power cable with metallic screen rods
Inventor: DALIN CARL-JOHAN
IPC: H01B7/285
Filed: 2015-03-20
Abstract: It is disclosed a multi-phase power cable comprising: a plurality of phase cores, each including an insulated electric conductor; a screen assembly comprising a metallic screen rod; a moisture barrier metallic sheet enclosing the plurality of phase cores and the screen rod; an outer jacket radially outer to the moisture barrier metallic sheet; and a multilayer arrangement comprising a first, second and third semiconducting water swellable layers surrounding the phase cores and in radial internal position with respect to the moisture barrier metallic sheet and in electric contact therewith, the screen assembly being arranged between said second and third semiconducting water swellable layers.
Patent NZ-735011-A (NZ)
Title: 1-heterocyclyl isochromanyl compounds and analogs for treating cns disorders
Inventor: HANANIA TALEEN G
IPC: C07D405/14
Filed: 2016-02-11
Abstract: Disclosed are compounds of Formula (I): (Formula (I)) and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
Patent NZ-742412-A (NZ)
Title: Methods and compositions for preventing norleucine misincorporation into proteins
Inventor: LAIRD MICHAEL
IPC: C12R1/19
Filed: 2013-09-19
Abstract: The present invention relates to methods and compositions for preventing incorporation of norleucine into proteins during recombinant protein production in bacteria. The present invention also provides microorganism host cells and nucleic acid molecules encoding mutant metA alleles having R27C or Y294C substitutions and mutant metK alleles having V185E or c1132del mutations for use with the methods and compositions provided herein.
Patent NZ-753901-A (NZ)
Title: Tap or faucet with safety interlock for near-boiling and chilled water
Inventor: BECROFT LEONARD FORSDICK
IPC: F16K35/14
Filed: 2019-05-27
Abstract: A two-way or four-way water tap dispenses near-boiling water on demand but has a safety interlock. A control valve assembly is attached to the tap. The interlock uses two disks pressed into contact, each having a single projecting sector. One disk is fixed to the valve body. The other disk, fixed to the handle, slides against the first. The disks must be pulled apart by sliding the handle while it is being turned to superimpose the sectors and turn the control valve, connecting the tap to the vented near-boiling water supply. A reed switch inside the fixed sector is activated by a magnet inside the rotatable sector and activates a near-boiling water pump as an extra safety measure.