baber/WOPTO huggingface dataset:
Patent PT-1153924-E (PT)
Inventor: TAREK MANSOUR
IPC: A61P1/16
Filed: 1995-04-19
Abstract: This invention relates to single enantiomers of novel cis-substituted 1,3-oxathiolanes, of formula (I) wherein R1 is hydrogen, and R2 is cytosine or 5-fluorocytosine, and pharmaceutically acceptable salts and esters thereof. This invention also relates to pharmaceutical compositions containing them and to the use of these compounds as antiviral agents, particularly in combination therapy.
Patent PT-1294874-E (PT)
Inventor: YEN-MING HSU
IPC: A61P37/08
Filed: 2001-06-08
Abstract: Methods of decreasing (e.g., inhibiting) the expression of wildtype CD154 on the surface of a target cell and methods of treating a patient suffering from or predisposed to a CD154-mediated disease. In these methods, a nucleic acid construct that directs expression of a mutant CD154 lacking at least a portion of the tumor necrosis factor homologous domain ("TNFH") is introduced into a target cell (such as a T helper cell or a cytotoxic T cell). The expressed mutant CD154 binds to wildtype CD154 inside the cell, rendering the wildtype protein unable to reach the cell surface.
Patent PT-1316568-E (PT)
Title: Unsaturated polyester resin composition
Inventor: FUJITA YUKIKO
IPC: C08J5/00
Filed: 2001-09-05
Abstract: Disclosed is an unsaturated polyester resin composition comprising an unsaturated polyester (A) and a polymerizable unsaturated monomer (B), wherein the "shrinkage stress upon cooling" of a cured article thereof is 17 MPa or less and the ratio of the "shrinkage stress upon cooling/elastic limit" is 1 or less. The cured article has excellent gloss retention and yellowing resistance.
Patent PT-1328814-E (PT)
Title: Method for in vivo identification of intracellular epitopes
Inventor: CATTANEO ANTONINO
IPC: G01N33/68
Filed: 2001-10-22
Abstract: A method is described for the in vivo identification of epitopes of an intracellular antigen comprising the steps of :a) co-transforming of cells by a first vector including the nucleotide sequence encoding for the region of an antibody able to recognise and bind the intracellular antigen and by a second vector comprising the nucleotide sequence encoding for a peptide; b) growing co-transformed cells in such an environment that only cells wherein the antibody region and peptide recognise and interact each other are able to replicate and/or be recognised because: the antibody region able to recognise and bind the intracellular antigen is associated with a first molecule; the peptide is associated with a second molecule; the interaction of the first with the second molecule generates a selectable phenotype and/or recognisable signal; and the interaction of the first with the second molecule occurs only when the antibody region and peptide recognise and interact each-other; c) selecting the b) cells and identify the peptide as epitope.
Patent PT-1310594-E (PT)
Title: Method of building a railway on a concrete slab and temporary tie plate for carrying out said method
Inventor: RADA NICOLAS
IPC: E01B9/40
Filed: 2002-10-21
Abstract: Rails (2) pre-mounted on their tie plates (11) are suspended above the location at which a concrete slab is to be poured. The position of the rails is then adjusted to move the bottom plate of temporary tie plates, disposed under the base of each tie plate, accurately to the location at which the tie plates must rest. Concrete slab is then poured up to the height of the temporary tie plates. <??>The rails are raised, after which the temporary tie plates are removed. The rails are then positioned on the slab, with the tie plates fixed to the corresponding anchor members. An Independent claim is also included for a temporary tie plate.
Patent PT-1427535-E (PT)
Title: Spray gun
Inventor: ROBINSON GEORGE WALTER
IPC: B05B1/30
Filed: 2002-09-16
Abstract: An apparatus for spraying liquid surface treatment material has a housing (11), a liquid inlet for supply of the liquid surface treatment material, and a gas inlet for supply of pressurized gas to be mixed with the liquid surface treatment material. The apparatus also has an outlet nozzle through which the gas and liquid surface treatment is sprayed, a control needle valve adapted to regulate the supply of the liquid surface treatment material to the outlet nozzle, and a gas supply passageway connecting the gas inlet to the outlet nozzle. A control means for controlling the control needle valve is provided in the form of a cap member (15) received on the housing (11) and engaged with the control needle valve. The cap member (15) is adjustable in the axial direction relative to the housing (11) to limit axial movement of the control needle valve. The cap member (15) and housing (11) are each provided with a plurality of indicators (16,17a,17b) which indicate the limit applied to the axial movement of the control needle valve thereby allowing for repeatable adjustment of the spray pattern of the apparatus.
Patent PT-1424996-E (PT)
Inventor: WALZ MICHAEL
IPC: A61P11/06
Filed: 2002-08-03
Abstract: The invention relates to a new process for producing powdered preparations for inhalation comprising a substance having a smaller particle size distribution and a substance having a larger particle size distribution, wherein a substance having a smaller particle size distribution and a substance having a larger particle size distribution are continuously metered into a suitable mixing container such that the quotient N of the delivery speed for the metering of the substance having the smaller particle size distribution and the delivery speed for the metering of the substance having the larger particle size distribution is at least as great as the quotient M of the total mass of the substance having the smaller particle size distribution and the total mass of the substance having the larger particle size distribution.
Patent PT-1515710-E (PT)
Title: Method of treating rosacea by topical application of a cyclohexane derivative
Inventor: CHOMCZYNSKI PIOTR
IPC: A61K31/045
Filed: 2003-06-09
Abstract: A method for topically treating rosacea is disclosed. In this method, an active material having the formula given below is applied to the patient at the site of said rosacea: wherein R<1 >is selected from -OH and C1-C3 alkyl OH; and R<2>, R<3>, R<4>, R<5 >and R<6 >are independently selected from -H, -OH, C1-C6 alkyl, and C3-C6 cycloalkyl. Preferred active materials include 1,2-cyclohexanediol, 1,3-cyclohexanediol, 1,4-cyclohexanediol, and mixtures of those materials. Methods for treating acne vulgaris, as well as colds, flu, sinusitis, and ear infections, using these actives are also disclosed.
Patent PT-1578658-E (PT)
Title: Semitrailer coupling
Inventor: ROTH-SCHULER CHRISTIAN
IPC: B62D53/08
Filed: 2003-10-31
Abstract: The semi-trailer coupling (1) comprises a coupling plate (4) and a bearing block (5) to attach the plate to the frame (3) of a tractor. The bearing block has a bearing area (6) and a fastening area (7). The coupling plate can be pivoted, and the fastening area enables it to be detachably fitted to the tractor frame. The bearing area has a larger cross section than the fastening are, extending in the direction of travel parallel to the swiveling axis.
Patent PT-1595072-E (PT)
Title: Fuel injector with an antirebound device
Inventor: CRISTIANI MARCELLO
IPC: F02M51/06
Filed: 2004-02-20
Abstract: A fuel injector (1) having an injection valve (7) with a movable pin (15); and an actuator (5) for moving the pin (15) between a closed position and an open position; the actuator (5) has a movable armature (10), and an antirebound device (20) interposed between the movable armature (10) and the pin (15) to connect the movable armature (10) and the pin (15) mechanically; the antirebound device (20) has a deformable elastic plate (32; 45; 48) which is annular in shape, is connected centrally to the pin (15), and is connected laterally to the armature (10) to transmit at least the closing movement of the injection valve (7) from the armature 15 (10) to the pin (15).
Patent PT-1652535-E (PT)
Title: Semi-solid mucoadhesive formulations
Inventor: FERNANDEZ ALVARO ACEBRON
IPC: A61K9/00
Filed: 2004-07-16
Abstract: Semisolid mucoadhesive formulations for vaginal application, with improved technical and organoleptic characteristics, which contain at least two bioadhesive gelling polymers and an active ingredient, useful in the prevention and/or treatment of various pathologies and disorders in human beings or animals.
Patent PT-1691953-E (PT)
Title: Pressure regulating device for a percussive hydraulic apparatus
Inventor: COMARMOND JEAN-SYLVAIN
IPC: B25D9/26
Filed: 2004-12-02
Abstract: The device has two parts (17, 18) mounted in a bore of the body, where the part (17) is immovable, and the part (18) is movable in the direction of the part (17) under the action of hydraulic fluid supply pressure. The movement of the part (18) causes deformation of a washer (19) for creating a passage on a drifting circuit which drifts a part of the fluid supply flow towards a hydraulic fluid retaining circuit to adjust inlet pressure.
Patent PT-1708987-E (PT)
Title: L-(-)-moprolol l-(+)-tartrate
Inventor: CAZZOLLA NICOLA
IPC: A61K31/133
Filed: 2005-01-14
Abstract: L-(-)-moprolol L-(+)-tartrate salt (2:1), method for preparing it and pharmaceutical composition comprising it.
Patent PT-1911963-E (PT)
Title: Electronic-injection fuel-supply system
Inventor: PASQUALI PAOLO
IPC: F02M57/02
Filed: 2006-10-10
Abstract: Described herein is an electronic-injection fuel-supply system (12) for an internal-combustion engine (1) having at least one injector (13) and a fuel pump (14); the fuel pump (14) is provided with: a variable-volume pumping chamber (20); a one-way intake valve (28); a one-way delivery valve (24); a mobile piston (21) that integrates within it the intake valve (28) and is coupled to the pumping chamber (20) to vary cyclically the volume of the pumping chamber (20) itself; and an actuator device (27) that impresses a reciprocating motion on the piston (21) and has an electromagnetic actuator (29) for actuating the piston (21) during an intake phase and a spring (30) for actuating the piston (21) during a delivery phase.
Patent PT-1978204-E (PT)
Title: Earth drill
Inventor: KROLLMANN KARL JOHANNES
IPC: E21B7/00
Filed: 2007-04-05
Abstract: The device has an encasing tube (5) surrounding an auger (4). A twin-head rotary drive (20) drives the auger in a rotating manner about a drilling axis. An ejecting device (10) discharges drill spoil from the auger, where the ejecting device has a telescopic discharge line (11) i.e. discharge pipe, for the drill spoil. A winch device changes the length of the line. The line extends longitudinally to a mast element (3) in a direction of a drilling axis. The auger is moved together with the ejecting device along the mast element. A hoisting cable is fixed to tube elements (14, 14', 14''). An independent claim is also included for a method for producing a borehole in the ground with an earth drilling device.
Patent PT-1900590-E (PT)
Title: Power supply system for a diesel locomotive
Inventor: EGGERS DETLEF
IPC: B60K5/08
Filed: 2007-08-30
Abstract: The engine has a main driving unit (1) which consists of a diesel engine with a number of loads (12-19) of electrical power. The powered generator (9) generates electrical power for the load from the main driving unit. The auxiliary diesel engine (11) is inserted in the working breaks of the main driving unit with the generator in driving connection.
Patent PT-2049513-E (PT)
Title: Piperidinyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
Inventor: XU YANPING
IPC: A61K31/454
Filed: 2007-04-27
Abstract: The present invention discloses novel compounds of Formula I: having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity.
Patent PT-2089141-E (PT)
Title: Method for cool drying.
Inventor: DIJCK WOUTER DENIS ANN VAN
IPC: B01D5/00
Filed: 2007-10-25
Abstract: Method for cool drying gas containing water vapor, where a gas is led through a secondary part of a heat exchanger, whose primary part is an evaporator of a cooling circuit. The temperature or the dew point is measured in the environment of the place where, when cool drying, the temperature of the gas to be dried is the lowest. The above-mentioned method also has the step of switching off the cooling circuit when the decrease of the lowest measured gas temperature (LAT) or the dew point during a predetermined period of time amounts to less than a preset value (y).
Patent PT-2216416-E (PT)
Title: Methods for detection of nucleic acid sequences in urine
Inventor: LICHTENSTEIN ANATOLY V
IPC: C07H21/04
Filed: 1998-05-29
Abstract: A method of analysing a target nucleic acid sequence in a urine sample, said method comprising assaying said urine sample for the presence of said target nucleic acid sequence that has crossed the kidney barrier. The present invention provides a method for detecting a non-host nucleic acid sequence in a patient, said method comprising assaying a urine sample, obtained from an individual, for a nucleic acid sequence that: 
(i) is from outside the urinary tract, 
(ii) has crossed the kidney barrier, and 
(iii) does not originate from the patient's endogenous nucleic acid sequences, wherein contaminating nucleic acids in the urine sample comprising greater than 1000 base pairs, or 1000 nucleotides when denatured are removed from the sample prior to detection of said non-host nucleic acid.
Patent PT-666929-E (PT)
Inventor: FRISCH STEVEN M
IPC: C12N5/10
Filed: 1993-10-13
Abstract: This invention relates to methods for converting a pathologic hyperproliferative human cell to its non-malignant phenotype. The method comprises introducing into the cell a nucleic acid encoding a polypeptide having adenovirus E1A activity and growing the cell under conditions such that the polypeptide is produced. This invention also relates to a method of converting a population of pathologic hyperproliferative cells in a subject to a non-hyperproliferative state by expressing, in some but not all of the hyperproliferative cells, an isolated nucleic acid sequence encoding a polypeptide having adenovirus E1A activity. In a further aspect, the invention relates to promoting differentiation of pathologically hyperproliferative cells.
Patent PT-765322-E (PT)
Inventor: BLADE ROBERT JOHN
IPC: A61K31/422
Filed: 1995-05-31
Abstract: PCT No. PCT/GB95/01249 Sec. 371 Date May 23, 1997 Sec. 102(e) Date May 23, 1997 PCT Filed May 31, 1995 PCT Pub. No. WO95/32966 PCT Pub. Date Dec. 7, 1995A compound of formula (I), wherein A is C1-6alkyl, -O-C1-6alkyl, -O-phenyl or phenyl, optionally substituted by C1-3alkyl or halogen; n is an integer of from 0 to 3; W is a group of formula (i), (ii) or (iii) where R is hydrogen or C1-4alkyl, x is -O-, -S-, -NH-, or -CH2-, Y is oxygen or sulphur and the chiral centre * in formula (i) or (ii) is in its (S) or (R) form or is a mixture thereof in any proportions; and Z is a group of formula (iv) -HC2CH2NR1R2(v) or (vi) where R1 and R2 are independently selected from hydrogen and C1-4alkyl and R3 is hydrogen or C1-4alkyl; and salts, solvates and physiologically functional derivatives thereof.
Patent PT-801896-E (PT)
Inventor: DOSCHER MARY EHLERS
IPC: A01N43/36
Filed: 1997-04-15
Abstract: There is provided a method for the control of pyrethroid-resistant insects and the protection of animals therefrom which comprises contacting said insects with a toxic amount of a formula I arylpyrrole compound. <CHEM>
Patent PT-892742-E (PT)
Inventor: STRUBE LUTZ
IPC: B65D39/10
Filed: 1997-04-02
Abstract: The invention concerns a lid for sealing a sheet metal drinks can, a sealing element (102) being associated with this lid. Within its surface, the lid comprises a breakable region which is delimited by a notched line (103) and is surrounded by a cylindrical central wall (106) of a central enclosure (W). The sealing element comprises a corresponding cylindrical part (112) which engages in the central wall. Engagement and counter-engagement elements (115, 109), which co-operate in the manner of a bayonnet closure, are provided at the base of the cylindrical walls. Pressure elements and pressure surfaces (117, 116), which are designed and arranged such that when the sealing element is rotated relative to the lid, the notched line is made to break open (104) and the pouring aperture is released, are further provided at the base of the sealing element and at the base of the lid surface (111), these pressure elements and pressure surfaces co-operating with one another in the axial direction. An edge flange (139) of the sealing element is urged sealingly with appropriate pre-stress onto an annular surface (107) at the upper end of the central enclosure (W) of the lid by rotation.
Patent PT-910595-E (PT)
Inventor: CONTI NATALE
IPC: B32B27/04
Filed: 1997-06-25
Abstract: PCT No. PCT/EP97/03321 Sec. 371 Date Jan. 12, 1999 Sec. 102(e) Date Jan. 12, 1999 PCT Filed Jun. 25, 1997 PCT Pub. No. WO98/02474 PCT Pub. Date Jan. 22, 1998Modified melamine-formaldehyde resins are made of a condensate of formaldehyde, urea, melamine and modifying agents which contains: (a) a combination of 5 to 25 wt %, with respect to melamine, of dicyanodiamide and 8 to 30 wt %, with respect to melamine, of water-soluble polyalcohol with at least two hydroxyalkyl groups, and/or (b) 1.5 to 20 wt % amines having the formulas (Ia)NR4R5-R1-X(Ia)and/or (Ib),NR4R5-R2-Y-R3-X(Ib)in which R1 and R3 are the same or different and depending on the meaning of X stand for a linear, branched or cyclic C1-C12 alkyl or alkylene radical and R2 stands for a linear, branched or cyclic C1-C12 alkylene radical; R4 and R5 can be the same or different and can stand for H or for a linear or branched C1-C12 alkyl radical; and X can stand for hydrogen, OH or NR4R5 and Y can stand for -O- or -NH-. The molar ratio of melamine to formaldehyde ranges from 1:1.2 to 1:5 and the molar ratio of melamine to urea ranges from 1:0.1 to 1:2.8. Also disclosed is the use of these resins to produce post-forming laminates.
Patent PT-897714-E (PT)
Inventor: PASTURA AMERIGO
IPC: A61Q11/00
Filed: 1998-08-08
Abstract: A mouthwash (I) comprises two separately packaged components (A) and (B), which are sold as a combination and mixed before use. (A) consists of an aqueous solution of hydrogen peroxide and an acid for adjusting the pH to below 4.5 and (B) consists of an aqueous or aqueous alcoholic solution of pH over 8, containing one or more of surfactants, flavourings and oral hygiene active agents plus 1-10 wt.% of a buffer salt of a non-volatile acid. Mixing (A) and (B) provides a solution having H2O2 content of 0.005-3.0 wt.% and pH 7 or higher.
Patent PT-971739-E (PT)
Inventor: CRANE R THOMAS
IPC: A61K39/39
Filed: 1998-04-01
Abstract: An aqueous adjuvant composition comprising an attenuated lipid A derivative and a surfactant or surfactants enhances the immunological response in a warm blooded animal to a protein antigen. Attenuated lipid A derivatives useful according to the subject invention include monophosphoryl lipid A and 3-O-deacylated monophosphoryl lipid A. A surfactant or mixtures of surfactants are dissolved in a solvant. 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine is a preferred surfactant. The dissolved surfactant is added to an attenuated lipid A derivative to obtain a mixture. The molar ratio of attenuated lipid A derivative to surfactant in the mixture is about 4:1. The solvent is evaporated and water is added to the resulting film. The suspension is sonicated in a 60  DEG C water bath until it becomes clear. Animals administered the adjuvant formulation exhibited increased antibody responses to a given antigen as well as displayed enhanced lymphocyte proliferative and cytotoxic T-lymphocyte responses. Intranasal administration of the aqueous adjuvant composition and an antigen stimulates the production of serum and mucosal secreted IgA.
Patent PT-1068818-E (PT)
Inventor: STEKELENBURG ALBERT
IPC: A45F5/02
Filed: 1999-07-12
Abstract: A carrier is disclosed for receiving and carrying an electrical connector head, such as a plug or a socket, which may be attached to the worker, such as by attaching it to clothing, a belt, or a work belt, the carrier receiving and carrying the electrical connector head of the electrical cord. The carrier has a sidewall forming a hollow body having an open end and a closed end, with the open end having a larger transverse dimension than the closed end, and an inserting channel through partially across the closed end. A clip extends from the exterior of the sidewall to clip the carrier to the worker, or to an article easily carried by the worker, such as a toolbox, or the like.  <IMAGE>
Patent PT-1016454-E (PT)
Inventor: ERIK LUDDECKE DR
IPC: B01J13/06
Filed: 1999-12-22
Abstract: Preparation of stable fine particle powders comprises:  (a) dissolving one or more substances (A) and one or more substances (B) in a super-critical, compressible fluid; and  (b) relaxing the fluid along a residence path, where the solubility limit of (A) is earlier than that of (B) in the residence path.  An Independent claim is included for an apparatus for carrying out the process comprising a first high pressure autoclave (2) for dissolving substance (A) in a super critical fluid and a second high pressure autoclave for dissolving substance (B) in a super critical fluid. Two separate feeds (3, 7) connected to relaxation devices (4, 8) relax both fluids so that their flows intersect.
Patent PT-1080202-E (PT)
Inventor: KRYS BANKIEWICZ
IPC: A61K47/48
Filed: 1999-05-26
Abstract: Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.
Patent PT-1056359-E (PT)
Inventor: MCEWEN JOHN WILLIAM
IPC: A23L33/15
Filed: 1999-02-24
Abstract: In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental exhaustion, disease states and the like. In one embodiment, the invention relates to a nutritional composition comprising a structured glyceride component and an antioxidant system. This nutritional composition has been shown to be highly effective in reducing immune system down regulation or dysregulation as a result of stress.
Patent SG-95585-G (SG)
Title: Light sensitive composition based on o-naphtoquinone diazides and light sensitive copying material produced therefrom
IPC: G03C1/56
Filed: 1985-12-13
Abstract: A light-sensitive mixture comprising a light-sensitive naphthoquinone-diazide-sulfonic acid ester corresponding to the formula:    <IMAGE>  I  wherein D represents a 1,2-naphthoquinone-2-diazide-5-sulfonyl or -4-sulfonyl radical; R1, R2, R3, R1', R2' and R3' each represent hydrogen, halogen, alkyl groups having 1 to 4 carbon atoms or radicals of the formula DO and n represents an integer from 2 to 18; not more than three DO radicals in total being present on one benzene ring. The mixture is useful for preparing printing plates or photoresists.
Patent SG-102892-G (SG)
Title: Composition of pregnanolole comprising a stable oil-in-water emulsion
IPC: A61K31/57
Filed: 1992-10-07
Abstract: A composition for intravenous administration of 3-alfa-hydroxy-­5-beta-pregnan-20-one (pregnanolone), comprising a stable oil-in-water emulsion, capable of being sterilized by auto­claving, of from 0.1 to 1.0 g of pregnanolone.