baber/WOPTO huggingface dataset:
Patent AU-2013252913-A1 (AU)
Title: Breast cancer prognosis, prediction of progesterone receptor subtype and|prediction of response to antiprogestin treatment based on gene expression
Inventor: LANGE CAROL
IPC: C12Q1/68
Filed: 2013-03-15
Abstract: The present invention provides gene expression profiles indicative of whether a patient afflicted with PR driven malignancies is likely to be responsive to treatment with a therapeutic compound that is an anti-progestin. By identifying such responsiveness, a treatment provider may determine in advance those patients who would benefit from such treatment, as well as identify alternative therapies for non- responders. Also, provided are methods of using gene expression profiles and assays for identifying the presence of a gene expression profile in a patient. Also, provided are gene expression signatures differentiating cells expressing a K388R progesterone receptor from a wild type progesterone receptor.
Patent AU-2013260169-A1 (AU)
Title: Electric motor driven tool for orthopedic impacting
Inventor: CHRISTOPHER PEDICINI
IPC: A61B17/16
Filed: 2013-03-08
Abstract: An orthopedic impacting tool comprises a motor, an energy storage means, a striker, and an anvil. The motor stores energy in the energy storage means and then releases it, causing the striker to apply a controlled force on an adapter to create a precise impact for use in a surgical setting. The tool may further comprise a combination anvil and adapter. The tool further allows forward or backward impacting for expanding the size or volume of the opening or for facilitating removal of a broach, implant, or other surgical implement from the opening. An energy adjustment control of the tool allows a surgeon to increase or decrease the impact energy. A light source and hand grips improve ease of operation of the tool.
Patent AU-2013262934-A1 (AU)
Title: LINGO-2 antagonists for treatment of conditions involving motor neurons
Inventor: MI SHA
IPC: A61K39/395
Filed: 2013-05-14
Abstract: The invention provides methods of treating diseases, disorders or injuries involving motor neuron survival and axonal growth, including amylotrophic lateral sclerosis, by the administration of a LINGO-2 antagonist. An exemplary method for promoting survival of a motor neuron, comprising contacting said motor neuron with an effective amount of a composition comprising a LINGO-2 antagonist selected from the group consisting of: (i) a soluble LINGO-2 polypeptide; (ii) a LINGO-2 antibody or antigen-binding fragment thereof; (iii) a LINGO-2 antagonist polynucleotide; (iv) a LINGO-2 aptamer; and (v) a combination of two or more of said LINGO-2 antagonists.
Patent AU-2013270593-A1 (AU)
Title: Camera system control for correcting bore-sight offset
Inventor: NEUFELD PETER WAI
IPC: G03B13/36
Filed: 2013-12-13
Abstract: A camera system is provided that provides a smooth and centered zoom, even at high levels of magnification. The camera system corrects for misalignment between the optical axis of a lens and center of an image sensor. As a result of the misalignment, the center of an image will move during a zoom movement. The current camera system corrects for the misalignment as the zoom movement occurs. The correction is matched to the speed of the zoom in order to provide a fluid zoom movement.
Patent AU-2013285605-A1 (AU)
Title: Due diligence systems and methods
Inventor: BERESFORD-WOOD BRET
IPC: G06Q50/18
Filed: 2013-06-10
Abstract: A system for performing due diligence on electronically stored documents is provided. A dynamic due diligence item (DDDI) is created by one user and associated with a particular document or piece of information by the system. The created DDDI is assigned to another user. The created DDDI is then routed by the system over a computer network to another user for review of the DDDI and the associated particular document or piece of information. In certain instances, after receiving the notification and opening the document, the system may enforce upon the second user a required action when the DDDI is presented.
Patent AU-2013286683-A1 (AU)
Title: Therapeutic bisphosphonates
Inventor: WIEMER DAVID
IPC: A61P9/00
Filed: 2013-07-03
Abstract: The invention provides novel pyrophosphate synthase inhibitors of formula I and formula II as well salts thereof; the invention also provides compositions comprising such inhibitors and methods for their use.
Patent AU-2013297064-A1 (AU)
Title: Methods, systems, and computer readable medium for active monitoring, memory protection and integrity verification of target devices
Inventor: AZAB AHMED
IPC: G06F21/50
Filed: 2013-03-15
Abstract: Methods, systems, and computer readable media for active monitoring, memory protection, and integrity verification of a target device are disclosed. For example, a normal world virtual processor and a secure world virtual processor are instantiated on a target device. A target operating system is executed on the normal world virtual processor. An integrity verification agent is executed on the secure world virtual processor. One or more predetermined operations attempted on the normal world virtual processor are trapped to the secure world virtual processor. The integrity verification agent is used to determine the effect of the execution of the trapped operations on the target device.
Patent AU-2013299605-A1 (AU)
Title: Topical composition comprising transformed bacteria expressing a compound of interest
Inventor: QVIT-RAZ NOGA
IPC: A61K36/02
Filed: 2013-08-07
Abstract: Compositions comprised of a population of transformed bacteria formulated for topical application to a subject are described. The population of transformed bacteria are created from a non-pathogenic bacteria and transformed to express a compound of interest for a therapeutic or a cosmetic purpose. In one embodiment, the composition is for protection of the skin from ultraviolet rays.
Patent AU-2013336509-A1 (AU)
Title: System for combining the clutch pedal and the acceleration pedal of a car
Inventor: MOHAMED SAID MAHMOUD
IPC: B60W10/02
Filed: 2013-09-12
Abstract: A device for combining the clutch pedal and the acceleration pedal into a single novel pedal. The invention concerns a device that makes it possible to discard the clutch pedal, keeping the clutch system that will function with a novel pedal that operates the acceleration and the clutch at the same time. It consists of a single pedal that accelerates the car and, at the same time, turns a cam (figure 1) to connect and disconnect the clutch disc. The device according to the invention is intended for cars.
Patent AU-2013343274-A1 (AU)
Title: Bacterial engineering
Inventor: WILLIAMS DAVID HUGH
IPC: C12N15/10
Filed: 2013-11-05
Abstract: Described is a process for producing a mutant bacterium which exhibits improved survival and/or growth under a selected growth condition, the process comprising the steps of: (a) generating a pool of mutant bacteria by transposon mutagenesis with an activating transposon (TnA), wherein the TnA comprises a promoter capable of increasing transcription of a gene at or near its insertion site; (b) growing bacteria from the mutant pool under the selected growth condition and under one or more reference conditions to produce two or more test cultures; and (c) comparing the distribution of TnA insertions between test cultures to identify a first class of genes which are disadvantageous for growth and/or survival under the selected growth condition and a second class of genes which are advantageous for growth and/or survival under the selected growth condition.
Patent AU-2013347975-A1 (AU)
Title: Improved peptide pharmaceuticals for insulin resistance
Inventor: NESTOR JOHN J
IPC: A61K38/16
Filed: 2013-11-20
Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
Patent WO-2015179893-A1 (WO)
Title: Protocole thérapeutique pour le traitement du cancer de l'ovaire
Inventor: KREMMIDIOTIS GABRIEL
IPC: A61K31/343
Filed: 2014-05-30
Abstract: La présente invention concerne une combinaison pharmaceutique destinée à traiter une maladie proliférative et comprenant un composé de formule (I), ou un sel, un solvate ou un promédicament de celui-ci, du carboplatine ou du cisplatine, et de la gemcitabine. La présente invention se rapporte, en outre, à un protocole thérapeutique pour la prise en charge du cancer de l'ovaire chez une femme impliquant l'administration de ladite combinaison à un sujet souffrant d'un cancer de l'ovaire récurrent ou persistant après traitement par une thérapie à base de platine. L'invention concerne également des nécessaires comprenant ladite combinaison, ainsi que l'utilisation de cette dernière dans le traitement d'une maladie proliférative.
Patent WO-2015010166-A1 (WO)
Title: Compositions et procédés pour minéralisation dentaire
Inventor: REYNOLDS ERIC CHARLES
IPC: A61K8/21
Filed: 2014-07-23
Abstract: La présente invention concerne des compositions pour minéraliser une surface dentaire, en particulier l'émail dentaire. L'invention concerne également des procédés pour minéraliser des lésions hypominéralisées (comprenant des lésions de subsurface) dans l'émail dentaire, causées par des caries dentaires, la corrosion dentaire et la fluorose. En particulier, l'invention concerne un procédé pour minéraliser une surface ou subsurface dentaire, comprenant la mise en contact de la surface ou subsurface dentaire avec un composé qui peut augmenter ou maintenir le pH d'une solution et un agent de minéralisation.
Patent AU-2014200507-A1 (AU)
Title: Catheter with imaging assembly
Inventor: ALLYN ROBERT
IPC: A61B1/005
Filed: 2014-01-30
Abstract: An imaging assembly (518) having a rigid-flex circuit (580) having an electronic component mounting portion and a camera mounting portion (582), wherein the electronic component mounting portion includes longitudinally spaced first and second rigid sections (561) 5 and a first flexible section (581) disposed between the first and second rigid sections (561), a first electronic component mounted on the first rigid section (561) of the electronic component mounting portion, a second electronic component mounted on the second rigid section (561) of the electronic component mounting portion, a camera (584) mounted on the camera mounting portion (582), the camera (584) communicatively connected to the first and second electronic 0 components, and a housing (550) in which the rigid-flex circuit (580) is disposed. The first flexible section (581) of the electronic component mounting portion is free from electronic components mounted thereon such that the rigid-flex circuit (580) is capable of bending at the first flexible section (581).
Patent AU-2014202444-A1 (AU)
Title: Capsule with sealing means
Inventor: YOAKIM ALFRED
IPC: A47J31/40
Filed: 2014-05-05
Abstract: A capsule (1) contains beverage ingredients such as ground coffee, tea or other ingredients and is configured for insertion in a beverage production device (2) in order to have a liquid under pressure have enter the capsule (1) and to interact with the ingredients (3) in the capsule (1). The capsule (1) comprises a base body (4) and a foil member (5) closing the base body (4) by being attached to a flange-like rim (6) extending from the side wall (7) of the base body (4) of the capsule (1). The base body (4) of the capsule (1) comprises a resilient sealing member (26), the sealing member (26) forming a hollow deflectable and compressible structure sufficient to deform under the closure forces applied by the bell-shaped member (9) onto the capsule holder (13) thereby providing sealing engagement. Figure 10 Fig. 10
Patent AU-2014211236-A1 (AU)
Title: Method for separating cell from biological tissue
Inventor: GOTO MASAFUMI
IPC: C12N5/07
Filed: 2014-01-31
Abstract: Provided is a cell separation method, whereby a cell having a high biological activity can be efficiently and stably separated from a biological tissue, characterized by comprising using a degrading enzyme composition that is prepared by adding, to a definite amount of a neutral protease and/or a protease derived from
Patent AU-2014225297-A1 (AU)
Title: Metal extraction from fines
Inventor: SPIRIDONOV PAVEL NICOLAEVICH
IPC: C22B3/42
Filed: 2014-03-07
Abstract: A method of recovering copper and other metals from fine and low grade fractions of oxide or oxide/sulphide mixes utilises fine fractions to prepare a pulp, adjusting the pH of the pulp, leaching the metal ions from the pulp, absorbing the metals on ion exchange resin and desorbing the loaded resin to recover the metal. Milling and screening the mixes obtains particles up to 0.5mm, usually 0.3mm and preferably 0.1mm.
Patent AU-2014225303-A1 (AU)
Title: A modular barrier system
Inventor: THRUSH STEPHEN ROY
IPC: E04G5/08
Filed: 2014-03-07
Abstract: Disclosed herein is a modular barrier system comprising elongate barriers adapted to conform to a substantially flat surface. An orientation of a first barrier with respect to a second adjacent barrier is selectively adjustable such that the barrier system provides a continuous barrier at changes in direction at an edge of the surface.
Patent AU-2014237405-A1 (AU)
Title: Systems and methods for hydrothermal conversion of biomass
Inventor: ATWOOD MATTHEW
IPC: C10L5/00
Filed: 2014-03-10
Abstract: Systems and methods are provided for synthesizing low nitrogen concentration organic liquids from biomass, such as algae, the organic liquids being suitable for refining into fuels and other chemicals. The biomass together with a solvent that is immiscible with water at room temperature are subjected to a subcritical hydrothermal treatment to disrupt cell structure and transform the biomass into a gas phase, a bio-oil phase, an aqueous phase and a solid phase. The aqueous phase contains most of the nitrogen. The resulting multiphasic mixture can be separated into four phases, including an aqueous phase and the organic liquid which consists of bio-oil dissolved in the solvent. Refined organic liquid can be recycled into the hydrothermal treatment as the solvent. The subcritical hydrothermal treatment can be performed at a generally low temperature and followed by a second hydrothermal treatment at a higher temperature.
Patent AU-2014244318-A1 (AU)
Title: Systems and methods for applying electrical stimulation for optimizing spinal cord stimulation
Inventor: GRILL WARREN M
IPC: A61N1/36
Filed: 2014-03-13
Abstract: Systems and methods for applying electrical stimulation to different sub-populations of targeted neurological tissue for optimizing spinal cord stimulation are disclosed. According to an aspect, a method includes applying a first pattern of electrical stimulation to a first sub- population of targeted neurological tissue of a subject. The method also includes applying a second pattern of electrical stimulation to a second sub-population of targeted neurological tissue of the subject, the second pattern of electrical stimulation being applied at a different frequency than the first pattern of electrical stimulation.
Patent AU-2014259543-A1 (AU)
Title: Small diameter endoscopic stapler
Inventor: KOSTRZEWSKI STANISLAW
IPC: A61B17/068
Filed: 2014-11-07
Abstract: SMALL DIAMETER ENDOSCOPIC STAPLER A surgical stapler (10) is described herein which includes a shaft portion (112) and a tool assembly (114) supported on a distal end of the shaft portion (112). The tool assembly includes an anvil (182) and a cartridge body (184) which rotatably supports a plurality of staples (186) within notches (196). At least one firing cam (138a) is provided to sequentially engage and rotate each of the staples (186) to fire the staples (186) from the cartridge body (184). In embodiments, the cartridge body (184) includes two spaced legs (188) which support two linear rows of staples (186). Each of the spaced legs (188) of the cartridge body (184) is supported within one of a first and a second cartridge channel (140a, 140b). The cartridge channels (140a, 140b) are fixed to opposite sides of a pivot member (157) which is pivotally supported at a distal end of the shaft portion (112) between the shaft portion (112) and the tool assembly (114) such that translation of the first and second cartridge channels (140a, 140b) in opposite directions effects articulation of the tool assembly (114) in relation to the shaft portion (112).
Patent AU-2014259751-A1 (AU)
Title: Thermal interface material pad and method of forming the same
Inventor: MATAYA RICHARD A
IPC: H01L23/36
Filed: 2014-05-01
Abstract: A thermal interface material (TIM) pad is disclosed for dissipating heat from a component. The TIM pad includes a plurality of thermal interface material layers and at least one graphene layer interposed between the plurality of TIM layers. A method for forming the TIM pad includes stacking the plurality of TIM layers with at least one graphene layer interposed between the plurality of TIM layers to reach a length for the TIM pad. The stacked layers are cut corresponding to a thickness for the TIM pad for compression against the component.
Patent AU-2014280936-A1 (AU)
Title: Polymer-factor ix moiety conjugates
Inventor: BOSSARD MARY J
IPC: A61P7/04
Filed: 2014-12-24
Abstract: Abstract Conjugates of a Factor IX moiety and one or more water solute e polymers are provided. Typically, the water 5 soluble polymer is polyethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates. 6063657_1 (GHMatters) P75618.AU.2 PETERB 18/12/14 '4X ,205 ic~ 116 kfDa 'q, A') iVano Conjugate 556 kD: SUE STJTE SWEET (RULE 26)
Patent AU-2014310360-A1 (AU)
Title: Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides
Inventor: LITTMAN BRUCE H
IPC: A61K47/48
Filed: 2014-06-11
Abstract: Embodiments disclosed herein provide compositions for conjugates, including fusion proteins, and methods of using them to treat a variety of conditions. In some embodiments, the conjugates and/or fusion proteins incorporate a 60-amino acid human homeodomain (e.g., peptides derived from human HOX genes), to translocate functional and regulatory peptides and proteins or other biologically active molecules such as nucleic acids, which are not naturally associated with the human homeodomain, across cell and nuclear membranes to intended sites of action without provoking an unwanted immune response that may reduce exposure to the conjugate and/or result in a clinical adverse event. In further embodiments, disclosed conjugates and fusion proteins can pass through the blood-brain barrier to allow entry into the CNS. In various embodiments, the disclosed compositions are suitable for delivery into a cell (i) the expression product of a gene of interest and/or (ii) novel peptides or polynucleotides to regulate gene function.
Patent AU-2014311969-A1 (AU)
Title: A compliance monitor for a medicament inhaler
Inventor: SUTHERLAND GARTH CAMPBELL
IPC: A61M15/00
Filed: 2014-08-29
Abstract: This invention relates to a compliance monitor for monitoring patient usage of a medicament inhaler. The medicament inhaler (1) includes a store (2) of medicament, a first housing (3) for housing the store of medicament, a medicament dispensing means (4,5) for delivering a dose of medicament, a mouthpiece (6) for directing the dose of medicament into the mouth of a user, and a removable and replaceable cap (7) for the mouthpiece. The compliance monitor includes a cap detection means (16), such as a switch, for determining when the cap is covering the mouthpiece and/or for determining that the cap is being removed or replaced, with respect to the mouthpiece. The compliance monitor may also include a dose detection means (14), such as a switch, for determining that a dose of medicament has been dispensed. Furthermore the cap (7) is attached to the first housing (3) by a tether or hinge (15)
Patent AU-2014324087-A1 (AU)
Title: Determining network maps of transport networks
Inventor: KILBY PHILIP
IPC: G06Q50/30
Filed: 2014-09-04
Abstract: This disclosure relates a processor determining a network map of a transport network by. The processor optimises for each of multiple sets of nodes a travel cost of trips with a start node and an end node in that set. This way, the processor selects from each of the multiple sets one node as a hub. The travel cost is based on whether the start node or end node is the hub. The processor then optimises for each node a direct travel time between that node and a hub to select an optimised hub for that node. Finally, the processor determines a network map comprising the selected hubs connected by a first transport mode and the remaining nodes connected to the selected hub by a second transport mode. Passengers need to change less often at the hub because the hub is placed at the most popular destination or origin.
Patent AU-2014361446-A1 (AU)
Title: Pyrometallurgical separation method of zirconia/hafnium oxide mixture
Inventor: ZHU XINGFENG
IPC: C22B34/14
Filed: 2014-09-29
Abstract: A separation method of a zirconia/hafnium oxide mixture. Putting the zirconia/hafnium oxide mixture, charcoal and pure bromine into a reaction for one hour under 650℃ to obtain bromide of zirconium and hafnium, adding the bromide of zirconium and hafnium into a molten salt mixture for distillation separation, and keeping a bottom of a distillation tower under 357℃ for two hours to obtain non-target substance; keeping for five hours at 357℃, and collecting high zirconium tetrabromide; saving residues in a kettle; performing distillation separation in a same device, hearting to 400 degrees, keeping for more than five hours to obtain hafnium tetrabromide, and using magnesium to displace the zirconium tetrabromide and the hafnium tetrabromide respectively to obtain pure zirconium and pure hafnium.
Patent AU-2014383048-A1 (AU)
Title: Systems and methods for enhancing audience measurement data
Inventor: BARNEY DAVID
IPC: H04H60/46
Filed: 2014-04-10
Abstract: The present disclosure provides systems and methods for enhancing audience measurement data. Offline and online audience measurement data may be compared and correlated to improve the quality of each data and source set. Positive correlations between the offline and online data sets related to a particular event may indicate demographic traits that are likely true, such that outliers may be removed from the set or considered at a reduced weight. Negative correlations may indicate that demographic information within a source set, such as the online measurement data, may be false or suspect.