Patent SG-11201900128X-A (SG)
Title: Anti-il-22r antibodies
Inventor: BLANCHETOT CHRISTOPHE FREDERIC JEROME
IPC: C07K16/28
Filed: 2017-07-14
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#11101111 0 11101 HOE 3E1 0 0111111 01 01011111010110111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\"\" WO 2018/011420 Al 18 January 2018 (18.01.2018) W I PO I PCT (51) International Patent Classification: KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, C07K 16/28 (2006.01) MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (21) International Application Number: OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, PCT/EP2017/067923 SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (22) International Filing Date: (84) Designated States (unless otherwise indicated, for every 14 July 2017 (14.07.2017) kind of regional protection available): ARIPO (BW, GH, (25) Filing Language: English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (26) Publication Language: English UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (30) Priority Data: EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 1612337.4 15 July 2016 (15.07.2016) GB MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, (71) Applicant: ARGENX BVBA [BE/BE]; Industriepark 7, KM, ML, MR, NE, SN, TD, TG). 9052 Zwijnaarde (BE). (72) Inventors: BLANCHETOT, Christophe Frederic Published: Jerome; c/o argenx BVBA, Industriepark Zwijnaarde 7, — with international search report (Art. 21(3)) Building C, B-9052 Gent (BE). URSO, Birgitte; c/o LEO — before the expiration of the time limit for amending the Pharma A/S, 55, Industriparken, 2750 Ballerup (DK). claims and to be republished in the event of receipt of _ SKAK-NIELSEN, Tine; c/o LEO Pharma A/S, 55, Indus- amendments (Rule 48.2(h)) triparken, 2750 Ballerup (DK). BERTELSEN, Malene; c/o — with sequence listing part of description (Rule 5.2(a)) = LEO Pharma A/S, 55, Industriparken, 2750 Ballerup (DK). _ VAN DER WONING, Sebastian; c/o argenx BVBA, In- =_ dustriepark Zwijnaarde 7, Building C, B-9052 Gen (BE). SAUNDERS, Michael; c/o argenx BVBA, Industriepark = Zwijnaarde 7, Building C, B-9052 Gent (BE). DE HAARD, = Johannes Joseph Wilhelmus; c/o argenx BVBA, Indus- - _ triepark Zwijnaarde 7, Building C, B-9052 Gent (BE). = (74) Agent: BOULT WADE TENNANT; Verulam Gardens, _ — 70 Gray's Inn Road, London Greater London WC1X 8BT = (GB). (81) Designated States (unless otherwise indicated, for every = = kind of national protection available): AE, AG, AL, AM, = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, _ CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, = = — (54) = F i g — 1-1 © ei ii- IL-19 Title: . 1 ANTI IL-20 -IL-22R ANTIBODIES IL-24 ,_ IL -22 (57) : The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly hu- man IL-22R. The invention also relates to pharmaceutical compositions compris- ing said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis. ,-1 ,-1 © -.... Il 0 ei 1120Rei. 1L2ORp I L2OR p 'i • 1 3 C