baber/WOPTO huggingface dataset:
Patent WO-2021101956-A1 (WO)
Inventor: CHEN XI
IPC: A61P37/02
Filed: 2020-11-18
Abstract: The present disclosure provides compositions and methods for identifying target-reactive T-cell receptors (TCRs). The identification may be based on comparing the frequency of a TCR before and after a marker-based selection. The identification may also be based on comparing the frequency of a TCR in a pool of cells stimulated by mutant and wildtype antigens.
Patent WO-2021126544-A1 (WO)
Title: High frequency device for heating food product, and associated systems and methods
Inventor: BROUNLEY RICHARD
IPC: A23L3/01
Filed: 2020-12-04
Abstract: In an embodiment, an apparatus for heat treatment of food product by radio frequency (RF) includes a transmission line having: a center conductor that includes a stack of food product packages, and an outer shield that at least partially encloses the center conductor. An RF connector is electrically coupled with the center conductor and with a source of RF voltage.
Patent WO-2021118928-A1 (WO)
Inventor: HIBBS BART
IPC: B64C39/02
Filed: 2020-12-07
Abstract: Systems, devices, and methods for: an unmanned aerial vehicle (UAV); at least one sensorless motor comprising a set of windings and a rotor; at least one propeller connected to the at least one sensorless motor; a microcontroller in communication with the at least one sensorless motor, wherein the microcontroller is configured to: determine a rotation rate of the at least one propeller; determine a rotation direction of the at least one propeller; provide an output to stop the at least one propeller and provide an output to start the at least one propeller.
Patent WO-2021133659-A1 (WO)
Inventor: VERGHESE SIMON
IPC: B60W50/00
Filed: 2020-12-18
Abstract: Disclosed are systems and methods that can be used for adjusting the field of view of one or more sensors of an autonomous vehicle. In the systems and methods, each sensor of the one or more sensors is configured to operate in accordance with a field of view volume up to a maximum field of view volume. The systems and methods include determining an operating environment of an autonomous vehicle. The systems and methods also include based on the determined operating environment of the autonomous vehicle, adjusting a field of view volume of at least one sensor of the one or more sensors from a first field of view volume to an adjusted field of view volume different from the first field of view volume. Additionally, the systems and methods include controlling the autonomous vehicle to operate using the at least one sensor having the adjusted field of view volume.
Patent WO-2021138500-A1 (WO)
Title: Scalable systems and methods for assessing healthy condition scores in renewable asset management
Inventor: VISWESWARIAH CHANDU
IPC: F03D17/00
Filed: 2020-12-30
Abstract: An example method comprises receiving historical wind turbine failure data and asset data from SCADA systems, receiving first historical sensor data, determining healthy assets of the renewable energy assets by comparing signals to known healthy operating signals, training at least one machine learning model to indicate assets that may potentially fail and to a second set of assets that are operating within a healthy threshold, receiving first current sensor data of a second time period, applying a machine learning model to the current sensor data to generate a first failure prediction a failure and generate a list of assets that are operating within a healthy threshold, comparing the first failure prediction to a trigger criteria, generating and transmitting a first alert if comparing the first failure prediction to the trigger criteria indicates a failure prediction, and updating a list of assets to perform surveillance if within a healthy threshold.
Patent WO-2021142234-A1 (WO)
Title: Muscle targeting complexes and uses thereof for treating myotonic dystrophy
Inventor: SUBRAMANIAN ROMESH
IPC: A61K48/00
Filed: 2021-01-08
Abstract: Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell surface receptor on muscle cells. In some embodiments, the molecular payload inhibits expression or activity of a DMPK allele comprising a disease-associated-repeat. In some embodiments, the molecular payload is an oligonucleotide, such as an antisense oligonucleotide or RNAi oligonucleotide.
Patent WO-2021167714-A1 (WO)
Inventor: TAHERZADEH BOROUJENI MAHMOUD
IPC: H04W74/08
Filed: 2021-01-11
Abstract: Des aspects de la présente invention concernent la communication d'un premier message d'accès aléatoire dans une procédure d'accès aléatoire en deux étapes, le premier message d'accès aléatoire comprenant une indication pour recevoir une ou plusieurs répétitions d'un second message d'accès aléatoire provenant de la station de base, et la communication, sur la base de l'indication, d'une transmission initiale du second message d'accès aléatoire et de la ou des répétitions du second message d'accès aléatoire.
Patent WO-2021150459-A1 (WO)
Title: Systems and methods for masking a recognized object during an application of a synthetic element to an original image
Inventor: ALLAN MAXIMILIAN H
IPC: G06T19/00
Filed: 2021-01-18
Abstract: An exemplary object masking system is configured to mask a recognized object during an application of a synthetic element to an original image. For example, the object masking system accesses a model of a recognized object depicted in an original image of a scene. The object masking system associates the model with the recognized object. The object masking system then generates presentation data for use by a presentation system to present an augmented version of the original image in which a synthetic element added to the original image is, based on the model as associated with the recognized object, prevented from occluding at least a portion of the recognized object. In this way, the synthetic element is made to appear as if located behind the recognized object. Corresponding systems and methods are also disclosed.
Patent WO-2021158466-A1 (WO)
Inventor: ATTUCKS OTIS CLINTON
IPC: A61P27/02
Filed: 2021-02-01
Abstract: La présente invention concerne des procédés de traitement d'affections oculaires réfractives et de complications associées à l'aide de composés de formule (I) et de compositions pharmaceutiques associées, soit seuls, soit en combinaison avec d'autres agents actifs.
Patent WO-2021183600-A1 (WO)
Title: Disinfection tracking network
Inventor: BAARMAN DAVID W
IPC: C12Q1/6888
Filed: 2021-03-10
Abstract: A disinfecting tracking network for creating healthier environments. The system and methods for tracking and utilizing this information to build and maintain healthier environments with a laboratory approach to data inputs. This system is a cloud based system with IOT interface and APIs to enable broad reaching inputs for analysis. This system creates a safer ecosystem and cross statistic sharing of performance parameters.
Patent WO-2021188803-A1 (WO)
Title: Compositions and methods for treating ocular disorders
Inventor: CIULLA THOMAS
IPC: A61K35/76
Filed: 2021-03-18
Abstract: The present invention relates to compositions and methods for treating ocular disorders. More specifically, the method includes non-surgical administration of gene therapies to the suprachoroidal space of the eye of a subject who is suffering from an ocular disorder.
Patent WO-2021202423-A1 (WO)
Title: Cancer classification with genomic region modeling
Inventor: GROSS SAMUEL
IPC: G16H50/20
Filed: 2021-03-29
Abstract: Methods and systems for detecting cancer and/or determining a cancer tissue of origin are disclosed. Fragments are grouped into genomic regions, wherein a region model is trained for each genomic region using a neural network with hidden layers. Fragments are input into the region models, and the outputs are used to generate a feature vector for cancer classification. In one embodiment, the region models are shallow neural networks configured to generate a score indicating a likelihood that a fragment is derived from a cancer biological sample. The feature vector is determined based on counts of fragments having scores above threshold scores for the various genomic regions. In another embodiment, the regions models are configured to generate a region embedding for an input methylation embedding of a fragment. The region embeddings are pooled by region and then pooled again to generate the feature vector.
Patent WO-2021211572-A1 (WO)
Title: Antisense therapeutics for the treatment of coronavirus
Inventor: FRIEBERTSHÄUSER EVA
IPC: A61K47/64
Filed: 2021-04-13
Abstract: Disclosed herein are embodiments of a compound useful for treating or preventing SARS-Cov-2 infections. Also disclosed is a method for administering the compound to a subject, particularly a human subject, to treat or prevent a SARS-CoV-2 infection in the subject. The compound may comprise an oligomer comprising a nucleic acid base sequence that is antisense to a gene, pre-mRNA or mRNA in the subject, such as a gene, pre-mRNA or mRNA of transmembrane serine protease 2 (TMPRSS2). The compound also may comprise a peptide sequence. In some embodiments, the compound is a peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO).
Patent WO-2021211663-A1 (WO)
Title: Chimeric myd88 receptors
Inventor: GOTTSCHALK STEPHEN
IPC: C07K14/47
Filed: 2021-04-14
Abstract: The present disclosure provides chimeric MyD88 receptors. Also provided are polynucleotides encoding the chimeric MyD88 receptors, vectors comprising the polynucleotides encoding the chimeric MyD88 receptors, and cell compositions comprising the chimeric MyD88 receptors, polynucleotides and/or vectors. Pharmaceutical compositions comprising the polypeptides, polynucleotides, vectors, or cells of the present disclosure, and their uses in treating a disease in a subject are also provided.
Patent WO-2021221911-A1 (WO)
Inventor: LAURENT CHRISTOPHE
IPC: G06F3/06
Filed: 2021-04-14
Abstract: Methods, systems, and devices related to balancing data are described. Data may be communicated using an original set of bits that may be partitioned into segments. Each of the original set of bits may have a first value or a second value, where a weight of the original set of bits may be based on a quantity of the set of bits that have the first value. If the weight of the original set of bits is outside of a target weight range, a different, encoded set of bits may be used to represent the data, the encoded set of bits having a weight within the target weight range. The encoded set of bits may be identified based an inversion of the original set of bits in a one-at-a-time and cumulative fashion. The encoded set of bits may be stored in place of the original set of bits.
Patent WO-2022119593-A1 (WO)
Title: Détection de probabilité de développer une sepsie
Inventor: TEJIDOR LILIANA
IPC: G01N33/68
Filed: 2021-04-21
Abstract: L'invention concerne des systèmes et des méthodes d'évaluation d'une probabilité pour qu'un individu développe une sepsie. Les systèmes et les méthodes peuvent consister à obtenir un ensemble de paramètres associés à l'individu comprenant un comptage de globules blancs (WBC) et une valeur de largeur de distribution de monocytes (MDW), et à déterminer si l'ensemble de paramètres constitue un état de risque élevé en comparant au moins le WBC et la valeur de MDW avec des critères prédéfinis respectifs. Dans le cas où il est déterminé que l'ensemble de paramètres correspond à l'état de risque élevé, les systèmes et les méthodes peuvent en outre consister à obtenir un paramètre secondaire associé à l'individu; et à fournir la probabilité pour que l'individu développe une sepsie.
Patent WO-2021222704-A1 (WO)
Inventor: AULD CHRISTOPHER
IPC: B33Y10/00
Filed: 2021-04-30
Abstract: Techniques for designing and fabricating thermal support regions via additive fabrication are described. Defects produced as a result of temperature differentials within an additive fabrication device that forms parts by sintering particles of material may be mitigated or avoided by directing energy to regions around a part that is sufficient to heat the material and cause it to partially sinter, but not enough to fully sinter the material. The mechanical properties of such a thermal support region may resist the effects caused by temperature gradients. In addition, or alternatively, the heating of the thermal support region material may reduce heat lost by nearby sintered material. In either or both cases, the thermal support region acts as a kind of 'volumetric armor' that surrounds some or all of the part and protects the part from defects.
Patent WO-2021225986-A1 (WO)
Title: System and method of manufacturing a composite core for an electrical transmission cable
Inventor: MCQUARRIE TERRY
IPC: H01B7/18
Filed: 2021-05-03
Abstract: A system and method for manufacturing a composite core for an electrical transmission and/or distribution cable is disclosed. The system includes a fiber creel assembly, a wet out tank, an alignment bushing system, a curing die, a coating system, a coiling system and a post cure oven system. They system utilizes a pultrusion structure which can pultrude fibers (wetted out in a resin) through a die and through the system. Eventually, the cured formed core can be coiled onto to a drum. Both a system and methods are disclosed.
Patent WO-2021262331-A1 (WO)
Inventor: GUPTA VASUDHA
IPC: G06F3/041
Filed: 2021-05-13
Abstract: A display device includes a first display panel including a first set of input/output (I/O) pads at a first side of the display device. The first set of I/O pads includes a first subset of palindromic I/O pads. A first display driver is operatively connected to the first set of I/O pads at the first side of the display device. The display device further includes a second display panel including a second set of I/O pads at the first side of the display device. The second set of I/O pads includes a second subset of palindromic I/O pads matching the first subset of palindromic I/O pads. A second display driver is operatively connected to the second set of I/O pads at the first side of the display device. The display device further includes a hinge that pivotably connects the first display panel to the second display panel.
Patent WO-2021237179-A1 (WO)
Title: Neurofeedback devices, systems, and methods for pain management
Inventor: ELBOGEN ERIC
IPC: A61B5/375
Filed: 2021-05-21
Abstract: Neurofeedback devices, systems, and methods for pain management. In some embodiments, the system includes one or more headset configured for detecting electrical activity of a brain of the subject; one or more electronic device in electronic communication with the one or more headset, the one or more electronic device comprising one or more processors configured to operate one or more software applications, which, when operated by the one or more processors, configure the one or more electronic device to perform the following functions: receive and analyze electrical activity data of the subject's brain from the one or more headset; and transmit an output to the subject, the output having a type selected by the subject, via a sound or visual output device based on an analysis of the received electrical activity data of the subject's brain; wherein the output is configured to reduce or relieve pain in the subject.
Patent WO-2022020019-A1 (WO)
Title: Cell identity for earth-fixed area with a moving cell
Inventor: SHRESTHA BHARAT
IPC: H04W60/00
Filed: 2021-06-07
Abstract: A method for wireless communication performed by a user equipment (UE) identifies multiple cell global identities (CGIs) broadcast by a cell. The method also determines a current tracking area identity of the UE from multiple tracking area identities of the cell based on a rule. The rule may be based on a preconfigured or predefined rule. The method selects a first CGI of the CGIs based on the determined tracking area identity.
Patent WO-2021257747-A1 (WO)
Title: Braking and signaling schemes for autonomous vehicle system
Inventor: KESSLER PATRICK
IPC: B60T7/22
Filed: 2021-06-16
Abstract: A method of decelerating a plurality of vehicles along a roadway may include, at a first vehicle, receiving, from an adjacent downstream vehicle, a first braking initiation signal and a first deceleration value indicating a deceleration rate of the adjacent downstream vehicle, determining a first distance to the adjacent downstream vehicle, and determining, based at least in part on the first distance, a second deceleration value configured to prevent the first vehicle from colliding with the adjacent downstream vehicle. The method may further include in accordance with a determination that the second deceleration value is greater than or equal to an upper deceleration value, decelerating at the upper deceleration value, and, in accordance with a determination that the second deceleration value is less than the upper deceleration value and greater than a lower deceleration target, decelerating at the second deceleration value.
Patent WO-2022015649-A1 (WO)
Inventor: CARLSSON JONAS
IPC: A61F5/443
Filed: 2021-07-12
Abstract: Un dispositif de capteur pour identifier une localisation de fuite d'effluent de stomie dans un système de stomie comprend une ouverture de stomie et des circuits électroconducteurs agencés selon un motif autour de l'ouverture de stomie. Le circuit électroconducteur comprend une première électrode et une seconde électrode espacée de la première électrode. La première électrode est subdivisée par une pluralité de résistances espacées le long d'une longueur de la première électrode. La seconde électrode s'étend sous la forme d'une bande continue de matériau conducteur. Le dispositif de capteur est configuré pour détecter une résistance électrique dans le circuit électroconducteur et identifier une localisation d'une fuite sur la base de la résistance électrique détectée.
Patent WO-2022026234-A1 (WO)
Inventor: LAURENT CHRISTOPHE
IPC: G06F11/10
Filed: 2021-07-19
Abstract: Methods, systems, and devices for generating a balanced codeword protected by an error correction code are described. A memory device may receive data bits for storage. Based on the data bits, the memory device may generate a codeword that includes the data bits, parity bits, and placeholder bits. The memory device may balance the codeword by inverting one or more packets of the codeword. After balancing the codeword, the memory device may store at least a portion of the codeword in memory so that a later operation or a decoding process reveals the packets that were inverted as part of the balancing process. Accordingly, the memory device may re-invert the appropriate packets to recover the original data bits.
Patent WO-2022066276-A1 (WO)
Title: Operating system level management of group communication sessions
Inventor: STAHL GEOFFREY
IPC: H04L29/06
Filed: 2021-07-23
Abstract: A device for providing operating system managed group communication sessions may include a memory and at least one processor. The at least one processor may be configured to receive, by an operating system level process executing on a device and from an application process executing on a device, a request to initiate a group session between a user associated with the device and another user. The at least one processor may be further configured to identify, by the operating system level process, another device associated with the other user. The at least one processor may be further configured to initiate, by the operating system level process, the group session with the user via the other device. The at least one processor may be further configured to manage, by the operating system level process, the group session.
Patent WO-2022026370-A1 (WO)
Title: Systèmes de stockage et de distribution de capsules de dentifrice et de solution
Inventor: LUSSIER MARCEL
IPC: A61Q11/00
Filed: 2021-07-26
Abstract: L'invention concerne une capsule hydrosoluble (1) pour le stockage et la distribution de dentifrice à usage unique (3) ou d'une autre substance, chaque capsule ayant de préférence une poignée de doigt (4) et un récipient de stockage (5) pour contenir une fourniture souhaitée de capsules. Chaque capsule présente une peau extérieure (2) qui peut être percée par une épingle de perforation de capsule (9, 11) de sorte que la compression de la capsule distribue la substance. En variante, une capsule peut avoir un point faible (12) de sorte que la compression de la capsule (1) provoque la rupture du point faible (12) et la libération de la substance (3) depuis la capsule (1).
Patent WO-2022031831-A1 (WO)
Title: Multi-lead measurement of biopotentials with wearable device
Inventor: CLARKSON JEFFREY P
IPC: A61B5/24
Filed: 2021-08-04
Abstract: A biopotential measurement device including a plurality of sensing electrodes and a controller is described. The plurality of sensing electrodes is adapted to measure one or more biopotential signals when the plurality of sensing electrodes is worn. The controller is coupled to the plurality of sensing electrodes and memory that stores instructions that when executed by the controller cause the biopotential measurement device to perform operations. The operations include collecting electrical signals over a first time period, each of the electrical signals associated with at least one of the plurality of sensing electrodes, mixing the electrical signals to generate a biopotential dataset that includes permutations of the electrical signals, and identifying a target biopotential signal included in the one or more biopotential signals based, at least in part, on the biopotential dataset.
Patent WO-2022032175-A1 (WO)
Title: Methods for the synthesis of protein-drug conjugates
Inventor: BORCHARDT ALLEN
IPC: A61K47/68
Filed: 2021-08-06
Abstract: The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.
Patent WO-2022036113-A1 (WO)
Title: Semi-permanent tattoos
Inventor: CAPUTO CHRISTOPHER B
IPC: A61K8/49
Filed: 2021-08-12
Abstract: The present disclosure relates to semi-permanent tattoos, for example, compositions comprising semi-permanent colorants and semi-permanent colorant precursors that include derivatives of genipin and lawsone. In some embodiments, the composition comprises: a semi-permanent colorant present in an amount of about 10% to about 20% w/w of the composition; a solvent present in an amount of about 65% to about 80% w/w of the composition; and a thickening agent present in an amount of 0.01% to about 0.3% w/w of the composition. In some embodiments, the composition further includes one or more of a film-forming agent, a humectant, and a preservative.
Patent WO-2022040292-A1 (WO)
Inventor: ROGERS JOHN A
IPC: A61B18/14
Filed: 2021-08-18
Abstract: An electronic system for multimodal diagnostic measurements and therapeutic interventions includes a plurality of element network layers vertically stacked one with another on a flexible substrate, each element network layer being bi-axially stretchable and comprising a plurality of elements configured in an addressable, interconnected array formed in a multilayered structure and operably performing a distinct function. The electronic system is a multimodal, multiplexed soft electronic system in a multilayered configuration that supports capabilities ranging from high-density spatiotemporal mapping of temperature, pressure and electrophysiological parameters, to options in programmable high-density actuation of thermal inputs and/or electrical stimulation, drug elution, radio frequency ablation, and/or irreversible electroporation ablation.