baber/WOPTO huggingface dataset:
Patent CA-3084445-A1 (CA)
Inventor: MUJACIC MIRNA
IPC: A61K35/17
Filed: 2018-12-07
Abstract: The present disclosure provides methods for genetically engineering T cells, such as CD4+ T cells and/or CD8+ T cells, for use in cell therapy. In some aspects, the provided methods include one or more steps for pooling enriched CD4+ and CD8+ cells, such as at a 1: 1 ratio, and then incubating the cells under stimulating conditions, introducing a recombinant polypeptide to the cells through transduction or transfection, and/or cultivating the cells under conditions that promote proliferation and/or expansion. In some aspects, the provided methods are an efficient, reliable means to produce genetically engineered T cells with a high degree of success.
Patent CA-3085241-A1 (CA)
Inventor: HEINEMANN INES
IPC: C07D401/12
Filed: 2018-12-17
Abstract: La présente invention concerne des thiophényluraciles substitués de formule générale (I) ou leurs sels, les radicaux de la formule générale (I) étant tels que définis dans la description, ainsi que leur utilisation comme herbicides, en particulier pour lutter contre les plantes adventices et/ou les mauvaises herbes dans les cultures de plantes utiles et/ou comme régulateurs de croissance des plantes destinés à influencer la croissance des cultures de plantes utiles.
Patent CA-3085294-A1 (CA)
Title: Routing system that incorporates hours of service into time estimates
Inventor: OZTURK YUSUF
IPC: G01C21/36
Filed: 2020-07-03
Abstract: Techniques for notifying a driver of locations at which the driver can stop to comply with hours of service (HOS) rules are provided. In some examples, a navigation application compares the amount of time a driver has driven a vehicle to HOS rules to determine the remaining time the driver may drive before violating the rules, and identifies potential rest stops reachable within the remaining time and displays the rest stops to the driver. In some examples, the navigation application predicts an amount of time it will take a driver to drive a generated route and compares the predicted time to HOS rules to determine a number or frequency of rest stops needed for the driver to comply. Based on the number or frequency of rest stops, the navigation application identifies potential rest stops near the route and displays the rest stops to the driver without altering the route.
Patent CA-3088127-A1 (CA)
Inventor: BANNEN LYNNE CANNE
IPC: A61K31/517
Filed: 2019-01-25
Abstract: Disclosed herein are compounds of Formula (I'). Compounds of Formula (I') inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
Patent CA-3088684-A1 (CA)
Title: Compound 5-[3-(2,5-dichloro-4,6-dimethyl-1-oxy-pyridin-3-yl)-[1,2,4]oxadiazol-5-yl]-3-nitrobenzene-1,2-diol in microparticulate form and its use in the treatment of parkinson's disease
Inventor: RUSSO DOMENICO
IPC: C07D413/04
Filed: 2012-12-12
Abstract: There is disclosed a crystalline compound of formula (II) (see formula II) in microparticulate form having a particle size specification with D10 equivalent circle diameter not less than 4 pm, a D50 equivalent circle diameter of 10-45 µm and a D95 equivalent circle diameter of not more than 80 µm. The compound of the invention is useful in the treatment of Parkinson's disease.
Patent CA-3090622-A1 (CA)
Title: Resine modifiee cetone-aldehyde et son procede de preparation
Inventor: KAI WEIHUA
IPC: C09D167/08
Filed: 2019-02-08
Abstract: La présente invention concerne une résine modifiée cétone-aldéhyde et son procédé de préparation. La résine modifiée cétone-aldéhyde comprend un polyester insaturé modifié cétone-aldéhyde, un alkyde insaturé modifié cétone-aldéhyde ou la combinaison de ceux-ci, et la résine modifiée cétone-aldéhyde comporte des fractions cétone-aldéhyde. Le procédé de l'invention comprend les étapes consistant à: faire réagir des composants monomères formant des résines alkydes insaturées et/ou formant des résines alkydes avec une résine cétone-aldéhyde, pour obtenir la résine modifiée cétone-aldéhyde. L'invention concerne également une composition de revêtement comprenant la résine modifiée cétone-aldéhyde ainsi qu'un article revêtu. La résine modifiée cétone-aldéhyde et la composition de revêtement selon la présente invention permettent d'obtenir un effet de séchage rapide significativement amélioré, tandis que d'autres propriétés ne sont pas amoindries ni même améliorées de manière observable.
Patent CA-3092638-A1 (CA)
Title: System and method of motion information storage for video coding and signaling
Inventor: YU YUE
IPC: H04N19/176
Filed: 2019-03-01
Abstract: A system and method are provided for inter-ceding video in which encoder and decoder memory requirements associated with storage of motion information related to collocated coding units is reduced. In some embodiments motion information related to only a single collocated coding unit may be stored at the encoder and decoder. In operation, if the encoder determines that motion information for a current coding unit should replace the currently stored motion information for the currently stored motion information for the collocated coding unit, then the encoder can replace the motion information at the encoder and transmit an indicator with the current coding unit to signal to the decoder that the motion information currently stored should be updated or replaced with the motion information associated with the current coding unit.
Patent CA-3093112-A1 (CA)
Inventor: BOYD MITCHELL A
IPC: E21B43/12
Filed: 2019-03-06
Abstract: L'invention concerne un piston de dérivation (10) comprenant un corps de piston (12) qui comprend une partie tête (16) située à une extrémité du corps de piston et une partie queue (13) située à une extrémité opposée du corps de piston. La partie tête comprend au moins un orifice d'écoulement (18), et la partie queue comprend au moins un passage (15). Un élément de vanne (32) est disposé à l'intérieur d'un alésage interne du corps de piston (12) et est mobile entre une position ouverte et une position fermée. Au moins une fiche (19) est située à l'intérieur d'un orifice d'écoulement respectif (18) et/ou d'un passage respectif (15), et est configurée pour réduire ou empêcher l'écoulement à travers l'orifice d'écoulement respectif (18) ou le passage respectif (15).
Patent CA-3094330-A1 (CA)
Inventor: POLLOCK TRESA M
IPC: C22C1/03
Filed: 2019-04-04
Abstract: L'invention concerne une séries d'alliages de Co, Ni, Al, W, Ta et Cr, l'alliage comprenant une solution solide de phases d'alliage gamma et gamma prime, la teneur en Ni étant supérieure à 25 % at., la teneur en Al étant supérieure à 10 % at., la teneur en Cr étant supérieure à 2 % at. et le rapport de Ni à Co étant compris entre 0,5 et 1,5.Dans un ou plusieurs exemples, l'alliage comprend en outre un ou plusieurs éléments parmi C, B et un métal élémentaire réactif.Des modes de réalisation de l'alliage possèdent simultanément une température de solvus élevée, une fraction élevée de la phase ?'-L12 de renforcement, une bonne résistance à l'oxydation et des caractéristiques de solidification hautement favorables.
Patent CA-3095039-A1 (CA)
Inventor: GUEGEL ROLAND
IPC: H04L29/06
Filed: 2019-03-22
Abstract: The disclosed systems, methods and apparatus enable alert messaging systems to send geographic location information with a geo-targeted message to end user wireless devices. The disclosed technology can be used to generate a plurality of messages where payload of a first message can include a message content, and where a payload of one or more additional messages can includes compressed location information. The user devices receiving the plurality of generated messages can process the compressed location information to determine whether the content of the received message should be displayed.
Patent CA-3095367-A1 (CA)
Inventor: LE KANG
IPC: C07D487/04
Filed: 2019-03-29
Abstract: The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.
Patent CA-3095913-A1 (CA)
Inventor: PERRINS ROB
IPC: A24F40/42
Filed: 2019-04-03
Abstract: Systems and methods related to the near elimination of second-hand smoke or vapour from the process of smoking or vaporizing tobacco or cannabis are provided. A vaporizing article is provided whereby a user may exhale into the article to capture a high percentage of the smoke and contaminants before they are released back into the surroundings. The article also provides for filtering gaseous by-products when the article is in idle mode. A prepackaged container for use with a vaporizing article is also provided. The container may be configured so as to optimize the heat distribution and consumption of product within the container.
Patent CA-3097182-A1 (CA)
Title: Computer-supported intraneural facilitation for vascular changes
Inventor: BUSSELL MARK
IPC: A61H1/02
Filed: 2019-04-23
Abstract: The disclosure is related to a system and method for operating a traction device to detect blood flow patterns in a subject for managing neuropathy related conditions through intraneural facilitation (INF). According to an embodiment, the INF system and method rely on the traction device for positioning the subject in one or more positions, and a processing device for processing intervening signals obtained by a probe positioned on the subject. The signals received from the probe may be used to determine a two dimensional (2D) plane blood flow pattern. Detected changes in the measured blood flow may be used to determine if further traction device positions are required to ensure that the intervening signals demonstrate normal blood flow patterns with improvements to the neuropathy condition. The 2D flow pattern may calculate at least one of Volume Flow (VF) and Pulsatility Index (PI) for each set of signals received.
Patent CA-3100710-A1 (CA)
Inventor: LANGER ROBERT S
IPC: A61M31/00
Filed: 2019-05-17
Abstract: La présente invention concerne des articles à redressement automatique, tels que des capsules à redressement automatique destinées à être administrées à un patient. Dans certains modes de réalisation, l'article à redressement automatique peut être conçu de telle sorte qu'il puisse s'orienter par rapport à une surface (par exemple, une surface d'un tissu d'un patient). Les articles à redressement automatique de la présente invention peuvent comprendre une ou plusieurs surfaces de mise en prise de tissu conçues pour venir en prise (par exemple par formation d'une interface, injection ou ancrage) avec une surface (par exemple une surface d'un tissu d'un patient). Dans certains modes de réalisation, l'article à redressement automatique peut présenter une forme et/ou une répartition particulière de densité (ou de masse) qui, par exemple, permet le comportement d'auto-redressement de l'article. Dans certains modes de réalisation, l'article à redressement automatique comprend des composants d'interface tissulaire. Dans certains modes de réalisation, chaque composant d'interfaçage avec le tissu peut comprendre une partie électriquement conductrice conçue pour une communication électrique avec un tissu et une partie isolante conçue pour ne pas être en communication électrique avec un tissu.
Patent CA-3101674-A1 (CA)
Title: In vitro method for monitoring the pathogen load in an animal population
Inventor: THIEMANN FRANK
IPC: C12Q1/70
Filed: 2019-05-27
Abstract: The present invention pertains to an in vitro method for monitoring the load of at least one pathogen in an avian population, the method comprising the following steps: collecting and pooling excremental sample material deriving from an avian population; homogenizing the pooled sample material obtained in step (a); diluting and optionally stabilizing the pooled sample material obtained in step (b) with aqueous buffer solution; lysing the cell material contained in the diluted sample material obtained in step (c); isolating nucleic acid material from the lysed sample material of step (d); detecting and quantifying at least one pathogen-specific target gene, or functional fragment thereof, contained in the nucleic acid isolate obtained in step (e); repeating steps (a) to (f) at consecutive points in time; and observing alterations in amount of the at least one pathogen specific target gene over time.
Patent CA-3103842-A1 (CA)
Inventor: LAVOIE PIERRE-OLIVIER
IPC: C12N5/10
Filed: 2019-06-27
Abstract: La présente invention concerne la production de protéines virales de la grippe modifiées dans des plantes. Plus précisément, la présente invention concerne la production et l'augmentation de la production de particules de type virus de la grippe (VLP) dans des plantes, les VLP comprenant les protéines virales de la grippe modifiées, telles que l'hémagglutinine (HA) de la grippe modifiée. La protéine HA peut comprendre une séquence d'acides aminés comprenant au moins une substitution lorsqu'elle est comparée à une séquence d'acides aminés de type sauvage correspondante. L'invention concerne en outre un acide nucléique codant pour la protéine HA modifiée. L'invention concerne en outre des procédés de production d'une particule de type virus de la grippe (VLP) et des procédés d'augmentation du rendement de production d'une particule de type virus de la grippe (VLP) dans une plante, une partie d'une plante ou une cellule végétale.
Patent CA-3104410-A1 (CA)
Inventor: GODSHAW DONALD E
IPC: A45C13/30
Filed: 2019-07-10
Abstract: In various embodiments, a carrying bag is disclosed which includes a one or more security panel assemblies comprising a first flexible material layer and a polymeric fiber matrix, such as a polymer fiber-based cut-resistant fabric, matrix or mesh. Various carrying straps are disclosed which include a first flexible fabric or webbing; and a second flexible fabric or webbing comprising a polymeric fiber matrix. Additional polymeric fibers, filaments, cables, threads or yams may be included in the security panel assemblies and straps, such as cut -resistant monofilament and multifilament fibers comprised of a polyethylene such as ultra high molecular weight polyethylene (UHMWPE), high-modulus polyethylene (HMPE), or High Performance Polyethylene (HPPE), for example.
Patent CA-3105065-A1 (CA)
Title: Methods of treating mitochondrial dysfunction
Inventor: FALK MARNI J
IPC: A61P3/00
Filed: 2019-06-26
Abstract: This disclosure is directed to methods of treating or preventing mitochondrial dysfunction or mitochondrial disease in a subject comprising administration of probucol, or a pharmaceutically acceptable salt thereof. This disclosure is also directed to methods of diagnosing genetic mitochondrial disease in a subject prior to and in association with said treatment or prevention. This disclosure is also directed to methods of assessing and managing a subject with mitochondrial dysfunction or mitochondrial disease using a composite measurement.
Patent CA-3106564-A1 (CA)
Title: Cancer vaccines for breast cancer
Inventor: PLASTERK RONALD HANS ANTON
IPC: A61K39/00
Filed: 2019-07-25
Abstract: The invention relates to the field of cancer, in particular breast cancer. In particular it relates to the field of immune system directed approaches for tumor reduction and control. Some aspects of the invention relate to vaccines, vaccinations and other means of stimulating an antigen specific immune response against a tumor in individuals. Such vaccines comprise neoantigens resulting from frameshift mutations that bring out-of-frame sequences of the GATA3, CDH1, MAP3K1, RUNX1, and TP53 genes in-frame. Such vaccines are also useful for 'off the shelf' use.
Patent CA-3111340-A1 (CA)
Title: A video encoder, a video decoder and corresponding methods
Inventor: GAO HAN
IPC: H04N19/96
Filed: 2019-09-03
Abstract: The present disclosure relates to methods and devices to be employed for encoding and decoding of image or video signal. They include determination of whether or not the size of a current block is larger than a minimum allowed quadtree leaf node size. If the size of the current block is not larger than the minimum allowed quadtree leaf node size, multi-type tree splitting is applied to the current block. The minimum allowed quadtree leaf node size is not larger than a maximum allowed binary tree root node size or the minimum allowed quadtree leaf node size is not larger than a maximum allowed ternary tree root node size.
Patent CA-3113170-A1 (CA)
Inventor: NAVARRO MIGUEL
IPC: G06Q10/10
Filed: 2021-03-24
Abstract: A computer server system comprises a communications module; a processor coupled with the communications module; and a memory coupled to the processor and storing processor- executable instructions which, when executed by the processor, configure the processor to receive, via the communications module and from a first device, a signal including a request to schedule access to a shared resource within a time window; identify, based on a load projection for the shared resource, at least one time period within the time window for the access to the shared resource; send, via the communications module and to the first device, a signal including the at least one time period and requesting confirmation that a particular one of the at least one time period is acceptable; receive, via the communications module and from the first device, a signal including confirmation that the particular one of the at least one time period is acceptable; determine that a current time has reached the particular one of the at least one time period; and responsive to determining that the current time has reached the particular one of the at least one time period, provide access to a node of the shared resource, the node having available bandwidth.
Patent CA-3115678-A1 (CA)
Title: Controlled translation method of affixing a termination to a multi-stranded tensile member
Inventor: CAMPBELL RICHARD V
IPC: B29C65/48
Filed: 2019-10-08
Abstract: A method for creating a termination by attaching some kind of fitting to the end of a tensile member such as a cable. The end fitting is provided with one or more internal cavities. Each cavity has a proximal portion that is adjacent to the area where the tensile member exits the fitting and a distal portion on its opposite end. A length of the tensile member's filaments is placed within this expanding cavity and infused with liquid potting compound. The method exploits the characteristic of a liquid potting compound as it transitions to a solid. Once the potting compound in at least a portion of the cavity has transitioned sufficiently to hold the filaments at a desired level, tension is placed on the tensile member and a small linear displacement may be imposed on the tensile member.
Patent CA-3115829-A1 (CA)
Title: Method for detecting anomalies on or in the surface of a structure
Inventor: COBB JOSEPH C
IPC: G06T7/00
Filed: 2019-10-22
Abstract: Described herein is a method of detecting anomalies on a surface of a structure. The method may comprise taking a thermal image of the surface of the structure. The method may further comprise taking a visual image of the surface of the structure. The method may then comprise conducting a thermal image numerical analysis on the thermal image. The thermal image numerical analysis may comprise obtaining a thermal image numerical value table. The thermal image numerical analysis may then comprise obtaining a surface nominal thermal value of the surface material. The thermal image numerical analysis may then comprise eliminating a first subset of pixels having a thermal value within a nominal thermal variation from the plurality of pixels. The thermal image numerical analysis may then comprise comparing the thermal value of each pixel of the plurality of pixels not in the first subset of pixels to the surface nominal thermal value to identify at least one anomaly. The thermal image numerical analysis method may then comprise removing a first number (n1) of first anomalies from the thermal image numerical analysis. Finally, the method may comprise comparing the first anomalies from the thermal image numerical analysis to the visual image.
Patent CA-3116420-A1 (CA)
Inventor: KANG CHANG SUN
IPC: A43C15/06
Filed: 2019-10-15
Abstract: A crampon includes a crampon base for fitting to an underside of an item of footwear, such as a shoe or a boot. A harness extends from the crampon base and may be attached to the crampon base using rivets. The harness and the crampon base define a space for receiving the item of footwear. The crampon base comprises at least one cleat assembly with a cleat base embedded within the crampon base. One or more spikes extend from the cleat base.
Patent CA-3117106-A1 (CA)
Inventor: WANG JINGFENG
IPC: C22C23/06
Filed: 2019-07-01
Abstract: The present disclosure provides a nickel-containing high-toughness controllably degradable magnesium alloy material, a preparation method therefor and use thereof, and relates to the technical field of magnesium alloys. The magnesium alloy material comprises the following components in percentage by mass: 0.3 to 8.5% of Ni, 0.5 to 28% of RE, with the balance being Mg and unavoidable impurities. RE represents rare earth elements. By adding Ni and RE elements to introduce an Mg12RENi-type long-period phase, an Mg2Ni phase and an MgxREy phase, the magnesium alloy material provided by the present disclosure significantly improves mechanical properties of the alloy material, the tensile strength being up to 510 MPa. At the same time, the presence of the Mg12RENi-type long-period phase and Mg2Ni phase enables the alloy material to be controllably degradable, and enables the degradation rate to be adjustable between 360 and 2400 mm/a. Downhole fracturing tools manufactured by using the magnesium alloy alleviates the technical problem existing in current downhole tools and satisfy the requirements in the field of oil and gas exploitation.
Patent CA-3118163-A1 (CA)
Title: Vecteur d'expression pour la cholesterol 24-hydrolase dans le traitement de la sclerose laterale amyotrophique
Inventor: PIGUET FRANCOISE
IPC: A61K38/44
Filed: 2019-10-28
Abstract: La présente invention concerne un vecteur destiné à être utilisé dans le traitement de la sclérose latérale amyotrophique associée ou non, à une démence fronto-temporale et des troubles du motoneurone apparentés, lequel vecteur comprend un acide nucléique codant pour la cholestérol 24-hydroxylase.
Patent CA-3118452-A1 (CA)
Inventor: MORETTI ALYSHA
IPC: A61K47/10
Filed: 2019-11-01
Abstract: The present disclosure provides oral care compositions that include a water-miscible base component, an opacifying agent, a structuring agent, and an active antiseptic agent effective for providing antiseptic activity, wherein the oral care composition is opaque and exhibits antiseptic activity.
Patent CA-3118772-A1 (CA)
Inventor: SIMON JEFFREY
IPC: B65G1/137
Filed: 2019-11-05
Abstract: The invention provides apparatus (410) suitable for use with a display unit (12). The apparatus (410) includes conveyor means which in one embodiment has a frame (448) with runners (450). An object (422) can be conveyed in a first direction from a first location (426) in the display unit (10) to a second location (428). Object (422) is suspended from runner (450) and movable between first location (426) and second location (428), using a pulley system activated via a handle (52). In another embodiment, the conveyor means may include a conveyor belt (24) driven by wheels (32) connected to a motor.