baber/WOPTO huggingface dataset:
Patent EP-3899535-A2 (EP)
Title: Screening assay
Inventor: MASON JODY MICHAEL
IPC: G01N33/50
Filed: 2019-12-20
Abstract: Disclosed are methods, kits and cells for screening for test compounds that are capable of inhibiting DNA-binding activity of a DNA-binding protein. The disclosed methods, kits and cells may include a reporter expression cassette that encodes a reporter expression product, wherein the reporter expression cassette comprises at least one binding site for the DNA-binding protein such that binding of the DNA- binding protein to the binding site inhibits expression of the reporter expression product. Also disclosed are methods for producing a helix-constrained peptide that may be used in the screening methods disclosed herein. The methods, kits and cells find application, for example, in the identification of antagonists that may be useful in the treatment of cancers involving the DNA-binding protein.
Patent EP-3899050-A2 (EP)
Inventor: CREED JENNIFER
IPC: C12Q1/6886
Filed: 2019-12-20
Abstract: Aberrant mitochondrial DNA (mtDNA) molecules having specific large-scale deletions and having an association with endometriosis are provided. The aberrant, or mutated, mtDNA may comprise the parent nucleic acid (i.e. the large sublimon), particularly when re-circularized, wherein adjacent nucleotides are fused following the deletion to form a junction site. Alternatively, the mtDNA may comprise the deleted strand (i.e. the small sublimon), also particularly when re-circularized to create a junction site. In addition, fusion transcripts resulting from such mutated mtDNA, and their putative protein products, are provided, where such transcripts and proteins are also associated with endometriosis. Hybridization probes and amplification primers and kits containing same are provided for detecting, diagnosing, or monitoring endometriosis.
Patent EP-3807276-A2 (EP)
Title: Inhibiteurs de kras g12c et leurs procédés d'utilisation
Inventor: ALLEN JOHN GORDON
IPC: A61K31/551
Filed: 2019-06-11
Abstract: La présente invention concerne des inhibiteurs de KRAS G12C, tels que le composé [...], leur composition, et des procédés d'utilisation de ceux-ci. Ces inhibiteurs sont utiles pour traiter un certain nombre de troubles, y compris le cancer du pancréas, le cancer colorectal et le cancer du poumon.
Patent EP-3719239-A2 (EP)
Inventor: YOSHIDA YUSUKE
IPC: E04G21/12
Filed: 2020-03-10
Abstract: A binding machine includes a wire feeding unit configured to feed two wires to be wound on an object to be bound, a wire guide configured to align the two wires in parallel, a binding unit having an engaging member in which the wires are to be engaged, and the binding unit configured to twist the wires which are wound on the object to be bound and which are engaged in the engaging member, a curl guide configured to curl the wires being fed by the wire feeding unit into a loop shape, an inductive guide configured to guide the wires curled by the curl guide toward the binding unit, and a parallel alignment regulation part configured to guide an alignment direction of the two wires to be engaged with the engaging member in a radial direction of the loop.
Patent EP-3709321-A2 (EP)
Title: Electrode element for a capacitor, capacitor and method for producing the electrode element
Inventor: DÖRR THOMAS
IPC: H01G11/86
Filed: 2020-03-12
Abstract: The invention relates to an electrode element (1) for an energy storage unit (200), having an electrode body (100) made of an active electrode material (E), wherein the electrode body (100) comprises: 
- at least one recess (110) on its surface or in its interior, 
- at least one partial volume (120) of lower density, or, 
- a cover material (D) that covers a surface area of the electrode body (100), at least section-wise, so that the surface area covered by the cover material (D) remains unwetted when in contact with an electrolyte. 
     The invention furthermore relates to a production method for the electrode element and to an energy storage unit (200) and an implantable electrotherapeutic device.
Patent EP-3845565-A2 (EP)
Inventor: LIU YICHIN
IPC: A61K39/395
Filed: 2015-11-18
Abstract: The invention provides antagonistic antibodies to BAC1 and methods of using the same for the treatment of neurological diseases and disorders.
Patent EP-3948327-A2 (EP)
Title: Noise reduction in an ultra-wideband (uwb) radar
Inventor: MCFADDEN JEFFREY
IPC: H01Q17/00
Filed: 2020-04-03
Abstract: An ultra-wideband (UWB) system includes an enclosure, and an ultra-wideband (UWB) transmitter array within the enclosure, the UWB transmitter array having a transmitter component that transmits electromagnetic waves toward a region-of-interest (ROI), the UWB array having a receiver component that receives reflected electromagnetic waves from objects in the ROI and generates object data. The system further includes a radar absorbing material positioned to receive electromagnetic waves transmitted from the transmitter component that are not directed toward the ROI, and a pattern recognition device having a processor configured to process the electromagnetic waves reflected from the ROI and to determine whether an object-of-interest (OOI) pattern is recognized within the object data.
Patent EP-4013893-A2 (EP)
Title: Diagnostic system
Inventor: ANDESHMAND SAYEED
IPC: G01N33/53
Filed: 2020-08-17
Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.
Patent EP-4178864-A2 (EP)
Inventor: CARBONI SALVATORE
IPC: B65B59/00
Filed: 2021-07-05
Abstract: In a device (400) and in a process for packaging articles to be packaged (1), supplied on a conveyor line (115) with a predetermined pattern, it is possible to eliminate buffers for the preparation of the layers to be packaged, while maintaining a high degree of flexibility for a wide range of formats, by comprising one or more transfer devices (200) that pick up the articles to be packaged (1) and deposit them in layers, each comprising a handling member (126) connected to a respective gripping device (127), both movable along three orthogonal axes, (X, Y, Z), each gripping device (127) having a plurality of gripping elements (128) each apt to pick up an article to be packaged (1) from said first conveyor line (115), wherein the gripping elements (128) are arranged in such a configuration as to form, on each gripping device (127), a single layer of articles to be packaged, each layer being obtained with one or more pickings from said first conveyor line (115), to be placed, in a single operation, in a respective container of said flow.
Patent EP-4162852-A2 (EP)
Inventor: SCHNITZER FRANK
IPC: A47L9/04
Filed: 2022-09-08
Abstract: Die vorliegende Erfindung betrifft einen Staubsauger (1) mit einer im Betrieb einem zu reinigenden Untergrund zugewandten Unterseite (7) sowie einer an der Unterseite (7) angeordneten Seitenbürste (6) mit zumindest einem Bürstenbüschel (11), wobei die Seitenbürste (6) in einem Eckbereich (10) der Unterseite (7) angeordnet und um eine quer oder geneigt zum Untergrund verlaufende Rotationsachse (8) rotierbar ist.Eine verbesserte Reinigungswirkung und eine einfache Umsetzung des Staubsaugers (1) werden dadurch erreicht, dass der Staubsauger (1) im Eckbereich (10) einen bezüglich des zur reinigenden Untergrunds (3) von dem zumindest einen Bürstenbüschel (11) höhenmäßig zurückversetzten Seitensaugmund (13) aufweist, welcher zur Rotationsachse (8) zumindest abschnittsweise beabstandet ist und über welchen im Betrieb mittels einer Saugeinrichtung Luft eingesaugt wird.
Patent EP-4205856-A2 (EP)
Inventor: RHEME CHRISTIAN
IPC: B02C23/02
Filed: 2022-12-20
Abstract: La présente invention concerne un système (10) pour le transfert de produit, notamment dans une chambre de traitement sous vide, ledit système de transfert (10) comprenant :- un corps (12) délimitant une cavité (14), et- une roue de transfert (20) logée dans ladite cavité (14) et munie d'au moins une poche (28) à sa périphérie, la roue (20) étant adaptée pour tourner de façon à amener du produit depuis ladite zone d'admission (A) jusqu'à ladite zone de distribution (D), dans lequel la roue de transfert (20) et le corps (12) coopèrent pour former une barrière sensiblement étanche à l'air entre les deux zones (A, D). L'invention concerne également un système de traitement incluant un tel système de transfert et un procédé de traitement correspondant.
Patent EP-4219446-A2 (EP)
Title: Traceless reductively cleavable linker molecules for peptide purification
Inventor: ZITTERBART ROBERT
IPC: C07C239/08
Filed: 2019-08-27
Abstract: The present invention relates to linker molecules of formula (1), X-T<sub>b</sub>-V<sub>a</sub>-U-Y-Z (1) and a method for purifying peptides using said linker molecules. The linker molecule can be coupled to a purification resin via the moiety X and to a peptide via the moiety Y under the release of the leaving group Z. T is an optional spacer moiety and V is an optional electron withdrawing moiety. U is an aryl or 5- or 6-membered heteroaryl moiety bound to at least one electron withdrawing moiety V, W or E. The linker is stable under acidic conditions and releases the peptide upon addition of a reducing agent.
Patent EP-4283805-A2 (EP)
Inventor: SAROKA MARY
IPC: H02G3/04
Filed: 2023-05-22
Abstract: A cable management system for a transport refrigeration system includes a trailer comprising an energy storage device and at least one movable axle. The cable management system includes a plurality of track sections extending between the energy storage device and the movable axle and a plurality of fasteners coupling the plurality of track sections. At least one track section of the plurality of track sections is movable such that the plurality of track sections are transformable between a first configuration having a first axial length and a second configuration having a second axial length. The second axial length is shorter than the first axial length.
Patent EP-4236383-A2 (EP)
Inventor: YANG YI
IPC: H04W4/02
Filed: 2019-08-30
Abstract: An electronic device includes communication circuitry configured to perform short-range wireless communication, ultra-wideband (UWB) communication circuitry configured to perform UWB communication, a secure element comprising a secure data storage configured to provide an execution environment isolated from an operating system (OS) of the electronic device, and a processor. The UWB communication circuitry performs ranging with an external electronic device, receives a first UWB signal including a medium access control (MAC) header and a MAC payload from the external electronic device, and determines, based at least on MAC payload information included in the MAC payload, whether to forward information included in the MAC payload information element to the secure element.
Patent EP-4262100-A2 (EP)
Inventor: NAGARAJA SUMEETH
IPC: H04B7/0404
Filed: 2018-04-27
Abstract: Methods, systems, and devices for wireless communication are described. Wireless communications systems may support beamformed transmissions between devices (e.g., to improve coverage range). The beamformed transmissions may depend on discovery and maintenance of receive and transmit beams over which a given device may communicate with another device. Various receive and transmit beams for a given device may be compared using reference signals. As the number of devices attempting to access a cell increases, the number of reference signals to be transmitted may scale proportionally. Large numbers of reference signals may flood time-frequency resources of the system and/or require excessive processing at a mobile device. Scrambling sequences for reference signals may be employed to improve efficiency of resource usage. In aspects, the scrambling sequences may be implicitly determined (e.g., based on resources over which the access request was transmitted). Such an implicit association may reduce the need for additional signaling.
Patent EP-4282875-A2 (EP)
Title: Reduced gluten grains and compositions thereof
Inventor: MOEHS CHARLES PAUL
IPC: C07K14/415
Filed: 2016-05-31
Abstract: Plants with reduced gluten grains and compositions thereof are disclosed herein.
Patent EP-4303253-A2 (EP)
Title: Composite material with thermoplastic toughened novolac-based epoxy matrix
Inventor: ZHU YAN
IPC: C08J5/24
Filed: 2017-06-20
Abstract: Pre-impregnated composite material (prepreg) that can be cured/molded to form aerospace composite parts. The prepreg includes carbon reinforcing fibers and an uncured resin matrix. The resin matrix includes an epoxy component that is a combination of a hydrocarbon epoxy novolac resin and a trifunctional epoxy resin and optionally a tetrafunctional epoxy resin. The resin matrix includes polyethersulfone as a toughening agent and a thermoplastic particle component.
Patent EP-0002003-A2 (EP)
Inventor: KUY BERT
IPC: A01N59/06
Filed: 1978-11-02
Abstract: The present invention relates to novel compositions of matter for use in medicine, for agricultural applications, for use in cosmetics comprising as active ingredient an aluminum hydroxy chloride which is thixotropic, which has an atomic ratio of aluminum to chlorine of from 5 to 1 to 6 to 1, and which contains the material in a concentration of from about 3 to about 20 weight per cent. For medical topical application a suitable carrier is imbued with such thixotropic microcrystalline aluminum chloride oxide hydrate.
Patent EP-0005005-A2 (EP)
Inventor: CORAN AUBERT YAUCHER
IPC: C08L23/26
Filed: 1979-03-01
Abstract: Thermoplastic compositions comprise blends of 15 to 65 parts by weight of thermoplastic crystalline polyolefin resin and 85 to 35 parts by weight of cross-linked rubbery chlorosulfonated polyethylene (cross-linked CSM rubber) per 100 total parts by weight of polyolefin resin and CSM rubber, in which the CSM rubber is cross-linked to the extent that no more than 40 weight percent of the rubber is extractable in toluene at 23 = C. Compositions having both thermoplastic and elastomeric properties contain the polyolefin resin in an amount up to 50 weight percent of the composition, and CSM rubber, cross-linked to the extent that no more than 20 weight percent of the rubber is extractable in toluene at 23°C., in an amount up to 85 weight percent of the composition. Compositions of the invention can be prepared by continuous mastication of a blend of thermoplastic crystalline polyolefin resin and uncured CSM rubber with curative for the CSM rubber at curing temperature until the required extent of cross-linking of the rubber is attained.
Patent EP-0023138-A2 (EP)
Inventor: OSHIMA HARUMI
IPC: F16D55/00
Filed: 1980-07-18
Abstract: A disc brake comprising a carrier member secured to a non-rotatable part of a vehicle, a caliper member 7 supported on the carrier member 4 and being displaceable relative thereto in the direction of the axis of a rotatable disc, and a pair of parallel pins 5,6 guiding the displacement of the caliper member 7. 
     In order to prevent accidental separation of the caliper and carrier members 4,7 during pad replacement engaging portions 10,11, 13.12, 15,16 are respectively provided on the carrier and caliper members 4,7 to engage with one another when one of the pins 6 is removed, the caliper member 7 is angularly rotated around the other pin 5 by a predetermined angle, and when the caliper member 7 is displaced in one direction with respect to the axis of the disc.
Patent EP-0030153-A2 (EP)
Inventor: MESSAGE STEPHEN ROY
IPC: A23G3/26
Filed: 1980-12-01
Abstract: A tablet coating apparatus is described, which comprises a rotatable tablet receiving surface, rotary driving means coupled to the surface, an applicator for supply of coating fluid to the tablets (as hereinbefore defined), applicator shutdown means, an air conduit for supplying air to the tablets, air control means for regulating the supply of air, the arrangement of the air conduit and tablet receiving surface being such that in operation of the apparatus air passes from the air conduit through a bed of tablets on the tablet receiving surface, temperature sensing means in the path of the exhaust air and control means connected to the temperature sensing means, the rotary driving means, the air control means and the applicator shutdown means, for shutting off the supply of air to the rotatable tablet receiving surface, causing the rotary driving means to cease to rotate the tablet receiving surface and causing the applicator shutdown means to shut down the applicator whenever the temperature detected by the temperature sensing means exceeds a first predetermined value in operation of the apparatus and for causing the applicator shutdown means to shut down the applicator whenever the temperature detected by the temperature sensing means falls below a second predetermined value in operation of the apparatus.
Patent EP-0033879-A2 (EP)
Inventor: BARL MANFRED DR
IPC: C07C279/12
Filed: 1981-01-24
Abstract: Novel 1,3-bis(dialkylaminoalkyl)guanidines and a novel process for their preparation by reaction of guanidinium salts with diamines at 140 to 250 DEG C. The novel 1,3-bis(dialkylaminoalkyl)guanidines which can be prepared by the process of the invention are useful starting substances for the preparation of auxiliaries in the plastics field, dyes, plant protection agents and pharmaceuticals.
Patent EP-0033582-A2 (EP)
Inventor: ROCK GAIL ANN
IPC: C07K14/755
Filed: 1981-01-08
Abstract: Factor VIII is obtained by (a) adding heparin to freshly obtained blood plasma collected into a calcium chelating anti-coagulant or collecting blood plasma by plasmapheresis using heparin and a calcium chelating anti-coagulant; (b) freezing the plasma; (c) resolubilising the plasma; (d) isolating a cryoprecipitate from the plasma; (e) resolubilising the cryoprecipitate; (f) adding a citrate saline heparin bufferto the resolubilised cryoprecipitate; (g) incubating the buffered, resolubilised cryoprecipitate, e.g. at 0 to 10°C for at least one hour, thereby insolubilising Factor VIII present in the cryoprecipitate using heparin-precipitable cold-insoluble globulin, the resulting Factor VIII-rich precipitate also including cold-insoluble globulin; (h) separating the Factor VIII-rich precipitate; and (i) isolating the Factor VIII therefrom. By this method, as much as 81 % of the Factor VIII can be recovered in the cryoprecipitate and as much as 62% of the starting Factor VIII activity with the cold-insoluble globulin.
Patent EP-0049700-A2 (EP)
Inventor: NEUHERZ ROBERT
IPC: A47C7/40
Filed: 1981-10-02
Abstract: The seating furniture consists of a seat part (1) and a back rest (2) which is adjustable in height in relation to said seat part (1) along guides (4). In order to be able to adjust the back rest (2) from an aesthetically attractive low position into a high position which can be selected at will for comfort and is best suitable for use of the furniture, a drive is provided for the infinitely variable adjustment of the back rest (2) along its guides (4). The infinitely variable drive which can be operated by hand consists of a crank (9), a drive shaft (10) penetrating the seat part (1) with a pinion (11) and a rack (12). The crank (9) or the end of the drive shaft (10) associated with it can be accommodated in the front region of the seat part (1) in a cavity (16) situated below the seat surface. <IMAGE>
Patent EP-0066038-A2 (EP)
Inventor: CASON WILLIAM CHARLES
IPC: G09G5/32
Filed: 1982-02-05
Abstract: Method for displaying and editing spatially related data in an interactive text processing system having a display (14), a keyboard (10), a printer (15) and a microprocessor (11) for storing conventional text data in a first format and spatially related data in a second format, consisting in converting a selected portion of the spatially related data in the first format to displayed data in the second format, and interactively editing the converted spatially related data that is displayed as if it were text data in first format.
Patent EP-0065759-A2 (EP)
Inventor: YOKOI FUMIAKI
IPC: A44B19/12
Filed: 1982-05-19
Abstract: Thermoplastic filamentary material is continuously formed into a row of helically coiled or zigzag coupling elements for slide fasteners. One of the coupling elements as thus formed is measured for a dimension thereof. The measured dimension is compared with a reference value to detect a dimensional error, if any, of the measured one of the continuous coupling elements. The tensioning of the thermoplastic filamentary material prior to being formed into the row of coupling elements is adjustably controlled on the basis of the dimensional error so as to remove the latter from the formed coupling elements. The measurement of the coupling element may be effected while the row of coupling elements as formed is being held at rest.
Patent EP-0079548-A2 (EP)
Inventor: VOM HOFE DIETER
IPC: G01F11/26
Filed: 1982-11-06
Abstract: Bei einem Verschluß eines Verpackungsbehälters (8) für flüssiges oder rieselfähiges Produkt mit mechanisch stabilisierender Hülle und dichtender Auskleidung (33) werden Hülle und Auskleidung mit Hilfe eines an ihre Öffnungen adaptierten Deckels (1) miteinander gekoppelt. Es soll eine wiederverschließbare, auch zur Aufnahme hygroskopischer Pulverprodukte abzudichtende Ausgießöffnung aufweisende Verpackung geschaffen werden. Erfindungsgemäß ist in die Produktaustrittsöffnung (2) eines auf die Hülle adaptierten Deckels (1) ein durchgehender Rohrstutzen (3) mit darin einzusetzendem, einen Dichtkonus (19, 20) mit Ventilkugeldichtsitz (20) am Auslaßende und eine Kugelkammer (22) am Einlaßende besitzender Kugelkäfig (16) mit frei darin beweglichser Ventilkugel (17) einzusetzen.
Patent EP-0084624-A2 (EP)
Inventor: NELLE GUNTHER DR-ING
IPC: G01B5/00
Filed: 1982-11-26
Abstract: A coupling apparatus for a length measuring instrument is disclosed. The length measuring instrument includes a scale, which defines a division, and a scanning unit. The scale is connected to a first object and the scanning unit is connected to a second object movable relative to the first. The scanning unit is coupled to the second object by a coupling arrangement which is rigid in the measuring direction, and the scanning unit is guided on an auxiliary guide which functions independently of the guidance for the second object. The coupling arrangement includes a pivot joint with two degrees of rotational freedom along axes perpendicular to the measuring direction for compensation of direction errors, and a linear guide having two degrees of translatory freedom oriented perpendicularly to the measuring direction for correcting for non-parallelism between the auxiliary guide of the scanning unit and the guide of the second object.
Patent EP-0079646-A2 (EP)
Inventor: VAN DE PAS JOHANNES CORNELIS
IPC: C11D3/02
Filed: 1982-11-08
Abstract: The invention pertains to aqueous liquid detergent compositions of the suspending type which comprise a nonionic detergent active material and/or derivative thereof in admixture with an anionic detergent active material and/or cationic detergent active material, and electrolytes which consist of one or more salting-out electrolytes and one or more auxiliary electrolytes having a lyotropic number of 9.5 or above, the combination of said salting-out and auxiliary electrolytes giving improved stability.
Patent EP-0057597-A2 (EP)
Inventor: HELAL BASIL HESSEIN
IPC: A61F2/42
Filed: 1982-01-29
Abstract: A small joint spacing prosthesis comprises an elongate silicone rubber body 1 reinforced by a Dacron or nylon string 2 and is made by moulding the body 1 with the string 2 therein. The middle of the body 1 forms a spacer 3 of spherical shape with flat end faces 4 providing for abutment of the bone ends. The remainder of the body 1 forms intramedullary stems 6 with rounded outer ends 5.