baber/WOPTO huggingface dataset:
Patent ES-8801728-A1 (ES)
Title: Method for performing nucleic acid hybridization assays.
IPC: C12Q1/68
Filed: 1987-03-16
Abstract: A method and a kit for the isolation and quantitative detection of a selected target nucleic acid sequence from solution employing two probes. A first probe is complementary to one portion of the target and is covalently attached to a first complexing agent (e.g., either an antigen or an antibody). The second probe is complementary to a different portion of the target and is associated with a reporter group. Following hybridization of the target and two probes in solution, a solid support coated with a second complexing agent (i.e., a corresponding antibody or antigen) capable of binding to the first complexing agent on the first probe is employed to immobilize the target-probe hybrid complex. A plurality of types of first probes may be used. Each type is attached to the same sort of complexing agent but each includes a nucleic acid sequence which is complementary to a different portion of the target.
Patent IE-902693-A1 (IE)
Title: Liquid suspensions of nitrofurantoin
Inventor: MCGOWAN MARGARET ANNE
IPC: A61K9/00
Filed: 1990-07-24
Abstract: Compositions, for the administration of nitrofurantoin to a human or other animal, comprising: (a) a safe and effective amount of nitrofurantoin particulates having a surface consisting of nitrofurantoin monohydrate, wherein said particulates have a mean particle size greater than about 200 mesh size;  (b) nitrofurantoin monohydrate;  (c) an effective amount of suspending agent; and  (d) water; wherein the pH of said composition is from about 1 to about 6; and said nitrofurantoin monohydrate is dissolved in said water at saturation level. The nitrofurantoin of this invention are highly efficacious for the oral delivery of nitrofurantoin.
Patent IE-902954-A1 (IE)
Title: Therapeutic agents for the treatment of peptic ulcer disease
IPC: A61K31/00
Filed: 1990-08-15
Abstract: Therapeutic agents for the treatment of peptic ulcer disease, containing as active ingredient, at least one compound of the general formula I wherein one of R<1> and R<3> is (wherein m is 1-5 R<4> represents a (C1-C4)alkyl group); the other one of R<1> and R<3> is hydrogen, (C3-C6)alkenyl or (C1-C8)alkyl which can be substituted with up to 2 hydroxyl groups or a (C1-C4)alkoxy group; and R<2> is (C1-C4)alkyl.
Patent IE-913585-A1 (IE)
Title: Product for use in treating nephropathies
IPC: A61K45/06
Filed: 1991-10-16
Abstract: A pharmaceutical composition containing an angiotensin converting enzyme inhibitor and an inhibitor of thromboxane A2 activity, or a pharmaceutically acceptable salt thereof, is useful in the treatment of nephropathies and hyperlipidaemia secondary to nephrotic syndrome.
Patent IE-903591-A1 (IE)
Title: Chroman derivatives
IPC: A61K31/35
Filed: 1990-10-08
Abstract: Chroman derivatives of the formula I  in which X, Z, R<1> to R<10> and m have the meanings stated in claim 1, and their salts show effects on the cardiovascular system.
Patent IE-904178-A1 (IE)
Title: Phase splitter arrangement
IPC: H03H11/18
Filed: 1990-11-20
Abstract: An arrangement for forming phase quadrature components of r.f. signals comprising phase splitting means for deriving initial phase quadrature components of the r.f. signals, means for generating from the initial quadratures components respective signals having substantially equal amplitudes, means for obtaining sum and difference resultant signals [I0, I0, Q0, Q0] of said equal amplitude signals and output means for rendering substantially equal the amplitudes of the sum and difference resultant signals.
Patent IE-914182-A1 (IE)
Title: Process for the preparation of 2-(2-bromo-2-nitroethenyl) furan
Inventor: GERNS FRED R
IPC: C07D307/38
Filed: 1991-12-03
Abstract: Bromonitroethenylfuran (BNEF) is prepared from furfural in a two-step process. A primary amine is reacted with furfural in an organic solvent at the reflux temperature of the solvent to form the Schiff base. The organic solvent and the water formed in the foregoing reaction are removed from the Schiff base, which is then dissolved in a polar, water-miscible solvent. Bromonitromethane is added to the Schiff base solution and reacts with the Schiff base to form BNEF, which can be readily isolated by precipitation.
Patent IE-904312-A1 (IE)
Title: Ultrasonic gas measuring device
Inventor: AYLSWORTH ALONZO C
IPC: G01N29/22
Filed: 1990-11-29
Abstract: An ultrasonic gas measuring device including a housing, end walls for the housing, the end walls having a gas inlet and a gas outlet provided therethrough, ultrasonic detecting means provided within the housing means, the ultrasonic means having a transmitter, operatively mounted on one end wall, and a receiver, operatively mounted on the other end wall, arranged at spaced locations within the housing, the housing incorporating gas processing means for dividing the gas flow at least at some instance during its flow through the housing, electronic circuitry functioning to detect and generate a signal in cooperation with the ultrasonic detecting means representative of the concentration of gas passing through the housing, the electronic means also generating a reference signal corresponding to the electronic signal delivered to the ultrasonic means, a phase shift provided within the electronic circuitry and effecting a shift of one of said signals to furnish an aligned phased relationship between the two signals whereby the concentration of the gas passing through the housing as detected by the ultrasonic means can be electronically computed and precisely determined by the said electronic means.
Patent IE-914388-A1 (IE)
Title: Novel methylenebisphosphonic acid derivatives
IPC: C07F9/576
Filed: 1991-12-17
Abstract: Bisphosphonic acid derivs. of formula (I) and their geometrical, optically active isomers and salts are new. In (I), R1, R2, R3 and R4 = opt. branched, opt. unsatd. 1-10C alkyl, opt. unsatd. 3-10C cycloalkyl, aryl, aralkyl, silyl, SiR3 or H, where at least one or R1, R2, R3 and R4 is H, and at least one is not H; Q1 = H, OH, halo, NH2 or OR1; R1 = 1-4C lower alkyl or acyl; Q2 = opt. branched, opt. unsatd. 1-10C alkyl, hydroxyalkyl, aminoalkyl where the O is opt. substd. by one gp.; and N is opt. substd. by 2 gps. from 1-4C lower alkyl or acyl or two gp. on N form opt. saturated or aromatic heterocylic ring or Q2 is opt. substd., opt. partially unsatd. 3-10C cycloalkyl, opt. bonded to opt. branched 1-4C alkylene gp. Specifically claimed are 21 cpds. including (1-hydroxyethylidene) bisphosphonic acid monomethyl (Ia) and monoethyl ester.
Patent IE-914533-A1 (IE)
Title: Syringe with protective housing
Inventor: HOLLISTER WILLIAM H
IPC: C07D401/04
Filed: 1992-01-02
Abstract: To provide a high degree of protection against the possibility of someone being accidentally punctured by a contaminated needle, the syringe of the present invention has directly connected thereto a protective housing, which can be pivoted to a position in alignment with the contaminated needle to envelop the same. As the housing is pivoted into the alignment position, locking mechanisms integral of the housing would fixedly retain the needle within the housing. The syringe of the present invention may be modified to include a housing containing an integral collapsible section and a sealer adapted to the distal portion of the housing such that, upon collapse of the collapsible section of the housing, the tip of the contaminated needle would penetrate into and be sealingly secured by the sealer. Another modification of the syringe of the present invention involves utilizing a collapsible hinge to connect the protective housing to the main body portion of the syringe. Upon collapse of the collapsible hinge, the longitudinal distance separating the housing from the main body of the syringe is reduced, thereby causing the tip of the contaminated needle to pierce and penetrate into the sealer and be sealingly retained thereby.
[US5232455A]
Patent IE-920269-A1 (IE)
Title: Lockable and releasable handles
Inventor: MCINTYRE BRENDAN
IPC: E05B13/10
Filed: 1992-01-28
Abstract: A lockable handle comprising a body (1), a barrel (2) slidable axially in a cavity (5), a tumbler (3) slidable transversely of the barrel (2) to engage the body (1), a bolt (8) on the barrel (2) for engagement with a base plate to prevent handle movement. A circumferential channel (12) on the barrel having different profiles at two angular positions around the circumference, and a pivoted trigger (4) engageable with the channel (12) to hold the bolt (8) in extended position and being only releasable therefrom by manual pressure when the barrel (2) is in one of the said angular positions. A key acts on the tumbler (3) to withdraw it from engagement with the body (1) so that the barrel is free to rotate. The barrel (2) has a portion of reduced diameter (15) defining the channel (12) at the angular position in which the trigger (4) is releasable and the channel (12) is of reduced width at the angular position in which the trigger is not releasable.
Patent IE-920385-A1 (IE)
Title: Psoriasis treatment
Inventor: BOGER ROBERT S
IPC: A61K31/505
Filed: 1992-02-05
Abstract: The present invention relates to the use of angiotensin II antagonists for the treatment of psoriasis.
Patent IE-921620-A1 (IE)
Title: Azacyclic derivatives
Inventor: GIARDINA GIUSEPPE
IPC: C07D401/06
Filed: 1992-07-01
Abstract: Azacyclic derivatives of formula (I), are kappa-receptor agonists and are useful in the treatment of convulsions, cough, asthma, inflammation, pancreatitis, arrhythmias, hyponatraemic disease states and cerebral ischaemia.
Patent IE-950818-A1 (IE)
Title: Curvable felt of fibrous material with random orientation
Inventor: BLOCK ROGER DE
IPC: D04H13/00
Filed: 1995-10-18
Abstract: The invention relates to crimped mineral wool fibres, ie. those in which the orientation of the fibres, instead of being parallel to a plane, is quasi-random. To permit the curvature of the felts in a temporary or permanent manner, they are provided on the convex side with a surfacing shoot, the rupture resistance of which is greater than 300 kPa such as, for example, a kraft paper of a surface mass which is greater than 60 g/m2. <Fig. 3>
Patent WO-9006057-A1 (WO)
Inventor: KOENIG HELMUT
IPC: A21B1/42
Filed: 1989-11-27
Abstract: Une installation pour le traitement de produits de boulangerie comprend un four de boulangerie (9), deux armoires de fermentation (10, 11) et une tour de refroidissement (12) formant chacun un compartiment de traitement (8) pour le produit de boulangerie. Les supports (4) porteurs du produit sont déplacés et amenés vers compartiments (8) par l'intermédiaire d'un convoyeur (1) qui s'étend au-dessous de tous ces compartiments (8) en émergeant des deux côtés, au-delà du compartiment le plus éloigné, pour y former des postes de chargement ou de déchargement de la pâte (36). Dans chacun de ces compartiments de traitement (8), les supports (4) sont guidés vers le haut, en une pile (15), et vers le bas en une autre pile (16). Les différents compartiments (8) ou leurs enveloppes (7) sont reliés étroitement entre eux, de sorte que l'installation ne nécessite que très peu de place.
Patent WO-9638625-A1 (WO)
Title: Verfahren und anlage zum zerkleinern eines cellulosischen materials
Inventor: ZIKELI STEFAN
IPC: C08B1/00
Filed: 1996-04-02
Abstract: Die Erfindung betrifft ein Verfahren zur Zerkleinerung eines cellulosischen Materials, welches Verfahren darin besteht, daß die Zerkleinerung mindestens zweistufig durchgeführt wird, indem (1) das cellulosische Material vorzerkleinert wird, wobei Teilchen verschiedener Größenfraktionen gebildet werden, (2) die bei der Vorzerkleinerung gebildeten Teilchen ohne Abtrennung irgendeiner Größenfraktion zu einer Vorrichtung transportiert werden, in welcher die Teilchen weiter zerkleinert werden.
Patent WO-9821537-A1 (WO)
Title: Vorrichtung zum austragen bzw. durchmischen von stückigem gut
Inventor: ROSENFELLNER GERALD
IPC: F27B1/21
Filed: 1997-11-07
Abstract: Die Erfindung beschreibt eine Vorrichtung zum Austragen bzw. Durchmischen von stückigem Gut aus einem Schachtofen, der einen nach unten und/oder mindestens zu einer Seite hin offenen Hohlkörper zum Ausbringen des Reaktionsgutes aufweist, wobei in dem Hohlkörper Schnecken sternförmig angeordnet sind, diese Schnecken in einer Ebene unterschiedlich lange Wellen aufweisen und/oder eine Schnecke als durchgehende Schnecke ausgebildet ist. Eine der möglichen Kombinationen aus drei verschiedenen Längen von fliegenden Wellen (2) ist die, daß man sie in dem Schachtofen (1) achteckig sternförmig anordnet, wobei jeweils die gegenüberliegenden fliegenden Wellen (2), gleich lang sind. Der Bereich des 'Toten Mannes', somit der unbewegte Raum im Zentrum des Schachtofens ist durch diese Kombination extrem verringert.
Patent WO-9838219-A1 (WO)
Title: Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
Inventor: FISCHER BERNHARD
IPC: A61K38/00
Filed: 1998-02-18
Abstract: Beschrieben wird ein Verfahren zur Gewinnung von vWF, bei welchem vWF bei einer niedrigen Salzkonzentration an einen Kationenaustauscher gebunden wird und durch fraktionierte Elution vWF mit hoher spezifischer Aktivität gewonnen wird, sowie eine Präparation mit gereinigtem vWF, welche durch dieses Verfahren erhältlich ist.
Patent WO-0100346-A1 (WO)
Title: Appareil amortissant les vibrations
Inventor: BOULTON GARY
IPC: B21B33/00
Filed: 2000-05-12
Abstract: L'invention concerne un appareil (40) amortissant les vibrations comprenant un corps sous forme de piston (42) de balance de cylindre d'appui positionnable pour le mouvement coulissant dans une enceinte sous la forme d'une cavité (44) dans le cale inférieur du cylindre d'appui (30) de la cage du laminoir (10). Le corps du piston est un logement qui joue le rôle d'un piston traditionnel. Un organe d'amortissement est formé intégralement avec le piston (42) pour produire l'amortissement des vibrations des cales des cylindres d'appui (24, 30) opposés. L'organe d'amortissement est un système d'absorption spécialement conçu pour fournir une rigidité accordée et des éléments d'amortissement qui agissent en parallèle et qui se trouvent dans un compartiment (46) et une extrémité terminale ou un couvercle du piston (42). Une seconde partie (56) du compartiment absorbant les vibrations du piston (42) comporte également des composantes d'absorption des vibrations. Cette partie (56) est formée intégralement avec le couvercle situé à l'extrémité du piston (42) en contact avec un fluide (52).
Patent WO-0103107-A1 (WO)
Title: Plectre pour instrument a cordes, dispositif emetteur/recepteur et appareil de traitement de signal
Inventor: CHICK STEVE
IPC: G10D3/16
Filed: 2000-07-05
Abstract: Un plectre (4) pour instrument de musique à cordes doté de plusieurs cordes conductrices (10), est constitué d'un corps non-conducteur (5) et d'une pointe conductrice (8). La pointe conductrice (8) est dimensionnée, de sorte qu'elle vienne en contact fugitif avec une corde (10) lorsque celle-ci est pincée avec le plectre. La pointe (8) est connectée électriquement à des circuits de surveillance qui produisent un signal de déclenchement à chaque fois que la pointe touche n'importe quelle corde (10). Un dispositif émetteur-récepteur est prévu pour surveiller le contact de la pointe (8) avec les cordes (10) et générer le signal de déclenchement. Le signal de déclenchement est à son tour reçu par un appareil de traitement de signal qui modifie la sortie signal audio de l'instrument de musique à cordes sous la commande du signal de déclenchement.
Patent WO-0208107-A1 (WO)
Title: Ensemble devidoir demontable
Inventor: HANNON KEVIN MICHAEL
IPC: B65H75/22
Filed: 2001-07-25
Abstract: Cet ensemble dévidoir (10) comporte un corps de bobinage (20) pourvu de plusieurs premiers dispositifs d'engrènement à chaque extrémité et de deux flasques (30) pourvues, chacune, de plusieurs seconds dispositifs d'engrènement complémentaires, les premiers et seconds dispositifs étant placés de manière à permettre un engrènement axial, avec possibilité de désengagement, de chaque flasque (30) avec l'extrémité correspondante du corps de bobinage (20). Ces deux séries de dispositifs d'engrènement (40) possèdent des faces d'engrènement en opposition orientées circonférentiellement en paires susceptibles de s'apparier, de sorte qu'une rotation relative dans une direction prédéterminée vers l'avant, de la position de désengagement à la position de verrouillage empêche le corps de bobinage (20) de se séparer axialement de la flasque (30). Un loquet de blocage unidirectionnel (53) est configuré pour coulisser sur une surface de déflexion (43).  Ce loquet de blocage (53) est conçu pour se déformer élastiquement en réaction à l'engrènement axial ou à la rotation relative. La surface de déflexion (43) définit un épaulement (44) autorisant un relâchement élastique du loquet de blocage (53) dans la position de verrouillage. Le loquet (53) comporte une surface de blocage venant au contact de l'épaulement (44) dans la position de verrouillage afin de résister à une rotation relative inverse et, partant, d'empêcher une séparation axiale accidentelle de la flasque (30) et du corps de bobinage (20).
Patent WO-03016916-A1 (WO)
Title: Identification et isolement de cellules souches somatiques et leurs utilisations
Inventor: SIMMONS PAUL JOHN
IPC: C12N5/074
Filed: 2002-08-15
Abstract: La présente invention concerne l'identification d'une population spécifique de types cellulaires, en particulier des cellules souches somatiques, et notamment des cellules souches hématopoïétiques, des cellules souches mésenchymateuses et des cellules souches kératinocytes. L'invention concerne également des procédés d'isolement et des utilisations des cellules souches. L'invention concerne en outre, dérivant des procédés de l'invention, un procédé permettant d'identifier une cellule souche. A cet effet, on commence par sélectionner un échantillon cellulaire incluant des cellules souches. On recherche sur une cellule la présence d'un enzyme de conversion de l'angiotensine ou l'un de ses fragments. Il ne reste plus qu'à identifier les cellules souches portant ladite enzyme ou l'un de ses fragments.
Patent WO-03105622-A1 (WO)
Title: Dispositif de transport d'articles
Inventor: VELLA FRANK WILLIAM
IPC: A63C11/02
Filed: 2003-03-07
Abstract: L'invention concerne un dispositif de transport (1) destiné à
une planche (2) de surf ou à un autre article allongé. Ce dispositif
comprend une bandoulière (3), une ceinture (4) et une partie de réception
(5). La partie de réception (5) comprend un rabat inférieur (6) qui
passe autour d'une partie centrale de la planche (2) et est attachée
à un rabat supérieur (7) par l'intermédiaire de boucles
de fermeture rapide (8) de façon à maintenir la planche (2) en place.
Lorsque ce dispositif de transport (1) n'est pas utilisé pour transporter
une planche de surf, il peut être transformé en sac d'usage général
à l'aide de fermetures à glissière (19) latérales,
le rabat inférieur (6) présentant alors la forme d'une poche
et le rabat supérieur (7) servant de rabat de fermeture. Une zone antidérapante
et/ou une poche gonflable peuvent être disposées sur une surface
intérieure du rabat inférieur (6) pour empêcher la planche
(2) de glisser. Ladite poche gonflable peut être gonflée à une
pression maximale, limitée par une valve de limitation de pression, au
moyen d'une pompe située sur la bandoulière (2).
Patent WO-03093286-A1 (WO)
Title: Disaccharides for drug discovery
Inventor: MEUTERMANS WIM
IPC: C07H17/04
Filed: 2003-04-24
Abstract: Methods are described for the preparation of combinatorial libraries of potentially biologically active disaccharide compounds. These compounds are variously functionalized, with a view to varying lipid solubility size, function and other properties, with the particular aim of discovering novel drug or drug-like compounds, or compounds with useful properties. The invention provides intermediates, processes and synthetic strategies for the solution or solid phase synthesis of disaccharides, variously functionalised about the sugar ring, including the addition of aromaticity and charge, and the placement of pharmaceutically useful groups and isosteres.
Patent AU-2002227528-A1 (AU)
Title: Reducing the level of bacteria and viruses in aquaculture
Inventor: ASHWORTH DAVID WILSON
IPC: A01N35/02
Filed: 2001-07-25
Abstract: A method of reducing the level of bacteria and viruses in a volume of water during aquaculture comprises:-(a) providing the volume of water to be stocked with farmed aquatic organisms or eggs thereof; (b) prior to the stocking, introducing into the water an aqueous solution of glutaraldehyde in an amount such as to provide in the water from 0.1 to 2 ppm of glutaraldehyde; (c) stocking the water with the farmed aquatic organisms or eggs thereof at a time when the concentration of glutaraldehyde is 0.1 to 2 ppm. (d) allowing the farmed aquatic organisms or eggs thereof to grow; and (e) optionally during a period of the growth, introducing into the water at least one further portion of an aqueous solution of glutaraldehyde in an amount such as to maintain the concentration of the glutaraldehyde at 0.1 to 2 ppm.
Patent AU-2001230672-A1 (AU)
Title: Shaft coupling
Inventor: STERVIK HANS
IPC: F16D3/72
Filed: 2001-01-25
Abstract: Drive shaft coupling having in-series bellows segments of different flexural resistance. The bellows segment nearest a tube section presents less flexural resistance than the immediate following bellows segment. Each individual bellows segment may be dimensioned in such a way that stress is distributed evenly over all bellows segments so that the component may be optimized; for example, with respect to installation and strength. The variations in flexural resistance between the adjacent bellows segments may be produced by variations in the thickness of material of the bellows segments, variations in the outside diameter of the bellows segments, variations in the inside diameter of the bellows segments, variation of the radial angles of each bellows diaphragm in relation to the longitudinal axis of the coupling member, variation of the distance between adjacently positioned bellows segments, and/or variation of the composition of the material of construction of the bellows segments, including varying a mixture of glass fiber and carbon fiber in an epoxy composite material of construction, as well as the directions of orientation of the constituent fibers.
Patent AU-2001255802-A1 (AU)
Title: Vehicular route optimization system and method
Inventor: JONES MARTIN KELLY
IPC: G08G1/123
Filed: 2001-03-01
Abstract: A vehicular route optimization system and method changes the order that a vehicle is expected to arrive at a plurality of destinations based on requests from users so that the vehicle arrives at the plurality of destinations at more opportune times for the users. The system includes memory, a first communications device, and a data manager. The memory stores data indicating an order that a mobile vehicle is expected to arrive at the plurality of destinations. The first communications device receives a request transmitted from a remote communications device, and the data manager, in response to the request, defines a new order that the mobile vehicle is expected to arrive at the plurality of destinations. The data manager also identifies one of the destinations and a particular time period based on the request and determines whether the vehicle is expected to arrive at the one destination during the particular time period, if the vehicle travels a route based on the new order. If the vehicle is expected to arrive at the one destination during the particular time period when the vehicle travels the route based on the new order, the data manager updates the data such that the data indicates the new order. The updated data can then be displayed to a driver of the vehicle, who follows the route based on the new order. Therefore, the vehicle should arrive at the one destination during the particular time period.