baber/WOPTO huggingface dataset:
Patent NZ-717140-A (NZ)
Title: Antibodies and assays for detection of folate receptor 1
Inventor: CARRIGAN CHRISTINA
IPC: A61K39/395
Filed: 2014-08-29
Abstract: The invention generally relates to antibodies or antigen-binding fragment thereof that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Said antibodies bind to an epitope of folate receptor 1 (FOLR1) which comprises at least one, two or three N-glycosylated amino acids. Methods of using the antibodies to monitor therapy are further provided.
Patent NZ-722918-A (NZ)
Title: Pcsk9 vaccines
Inventor: GALABOVA GERGANA
IPC: C07K16/40
Filed: 2015-02-23
Abstract: The present invention relates to a vaccine capable to induce production of antibodies directed to PCSK9 in vivo.
Patent NZ-728442-A (NZ)
Title: Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
Inventor: LAI JIN-WANG
IPC: A61K9/50
Filed: 2005-10-21
Abstract: The disclosure relates to a pharmaceutical composition comprising a plurality of taste-masked particles, wherein the task-masked particles comprise: (a) a drug-containing core particle; and (b) a taste-masking membrane on said drug-containing core particle comprising a combination of a water-insoluble polymer and a gastrosoluble inorganic or organic pore-former at a ratio ranging from about 85/15 to about 65/15 wherein the composition exhibits acceptable taste-masking when the composition is placed in the oral cavity for 60 seconds and the composition releases not less than about 60% of the dose in 30 min when tested for dissolution using United States Pharmacopoeia Apparatus 2 (paddles at the rate of 50 rpm in 900 mL of pH 1.2 buffer); and (2) a plurality of rapidly-dispersing microgranules with an average particle size of not more than about 400 µm comprising (i) a sugar alcohol or a saccharide or a combination thereof and (ii) a disintegrant, each having an average particle diameter of not more than about 30 µm, wherein the ratio of said sugar alcohol, saccharide or combination thereof to said disintegrant in the rapidly-dispersing microgranules is from about 90/10 to about 99/10.
Patent NZ-731398-A (NZ)
Title: Noscapinoid-producing microbes and methods of making and using the same
Inventor: SMOLKE CHRISTINA D
IPC: A61K31/33
Filed: 2015-11-16
Abstract: Engineered non-plant cells that produce a benzylisoquinoline alkaloid product that is a derivative of canadine along a metabolic pathway that converts canadine, or an analog of canadine, to a noscapinoid product are provided. Methods of culturing engineered non-plant cells that produce a noscapinoid product and pharmaceutical compositions are also provided. Use of the noscapinoid product, for example in the treatment of cancer or research applications, is also provided.
Patent NZ-738995-A (NZ)
Title: A guide vane assembly
Inventor: VAZ GUY ANDREW
IPC: F03D7/06
Filed: 2015-06-24
Abstract: Disclosed herein is a guide vane assembly comprising a rig structure configurable with a turbine and having an inner portion and an outer portion forming extremities thereof, a sail and an actuator assembly. The sail is coupled to the rig structure and shaped for presenting a trough to a flow of impinging fluid, the trough having a depth defined from the rig plane. The sail extends from the outer portion towards the inner portion of the rig structure to terminate at an inner edge whereat a vent is defined. The fluid impinging on the sail is concentrated at the trough and redirected towards the turbine from the vent.
Patent NZ-741296-A (NZ)
Title: Novel peptides and combination of peptides for use in immunotherapy against various cancers
Inventor: WEINSCHENK TONI
IPC: A61K38/04
Filed: 2016-12-05
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes of PRAME (SEQ ID NO: 32 - VQLDSIEDLEV),alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Patent NZ-754040-A (NZ)
Title: Wind power plant
Inventor: KRIEGER KLAUS
IPC: F03D7/02
Filed: 2017-11-30
Abstract: The invention relates to a wind power plant having at least one rotor (1), wherein the rotor (1) has at least two rotor blades (2), wherein each rotor blade (2) is rotatable about a substantially radially aligned adjustment axis (4), wherein at least one angle adjustment device (5) is provided for adjustment of the rotor blades (2), wherein the angle adjustment device (5) has at least one control disk (8) and at least two cam disks (9) interacting with the control disk (8), wherein each cam disk (9) is rotatably mounted about a rotation axis, and wherein the rotation axis of the respective cam disk (9) coincides, and is in particular superimposed, together with the respective adjustment axis (4) of the respective rotor blade (9). The noise development, the maintenance expense, and/or costs of a wind power plant are reduced in that the cam disks (9) are functionally effectively permanently coupled via at least one coupling element (18).
Patent NZ-754388-A (NZ)
Title: Vaccine for intrauterine disease
Inventor: BICALHO RODRIGO
IPC: A61P15/00
Filed: 2013-10-08
Abstract: Provided are compositions and methods for use in prophylaxis of puerperal metritis and improving reproductive function of ruminants. The methods and compositions are for subcutaneous administration and are provided as veterinary compositions and as articles of manufacture. The veterinary composition can contain whole cells selected from whole cells of Escherichia coli (E. coli), Trueperella pyogenes (T. pyogenes), Fusobacterium necrophorum (F. necrophorum) and combinations thereof; and/or proteins selected from F. necrophorum leukotoxin (LKT), E. coli type 1 fimbrial adhesin (FimH), T. pyogenes pyolysin (PLO), and all combinations of the whole cells and the proteins.
Patent NZ-755300-A (NZ)
Title: Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
Inventor: LEE BONG YONG
IPC: A61K31/454
Filed: 2018-02-07
Abstract: The present invention relates to a heterocyclic compound represented by Chemical Formula 1 that can be used for the prevention or treatment of diseases caused by abnormality in a PRS (prolyl-tRNA synthetase) activity, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.
Patent PT-100790-A (PT)
Inventor: PEFFLY MARJORIE MOSSMAN
IPC: A61K8/41
Filed: 1992-08-19
Abstract: The present invention relates to hair spray compositions useful for spray application to the hair comprising from about 0.01 % to about 2 % of an ionic fluorosurfactant, from about 0.1 % to about 15 % of an ionic resin and a liquid vehicle, wherein the hair spray compositions are characterized by utilizing silicone macromer containing hair setting resins and/or by containing relatively high amounts of water, i.e., water and higher. This invention also relates to hair spray compositions useful for spray application to the hair comprising from about 0.01 % to about 2 % of an ionic fluorosurfactant, from about 0.1 % to about 15 % of an ionic silicone macromer-containing hair setting resin, and a liquid vehicle. This invention further relates to hair spray compositions comprising from about 0.01 % to about 2 % of an ionic fluorosurfactant, from about 0.1 % to about 15 % of an ionic silicone macromer-containing hair setting resin, and a liquid vehicle, wherein the hair setting resin has a weight average molecular weight of at least about 300,000.
Patent PT-103341-A (PT)
Title: Sistema de alimentação (evaporador) e refrigeração para centrais dessalinizadoras (compressão de vapor)
Inventor: LOPES JOAO BAPTISTA SILVA
IPC: C02F103/08
Filed: 2005-09-07
Abstract: A PATENTE OBJECTO DO PRESENTE INVENTO, APRESENTA UM SISTEMA DE EVAPORAÇÃO POR COMPRESSÃO DO VAPOR DE ÁGUA DE VÁRIAS CALDEIRAS (3) DISPOSTAS INDEPENDENTEMENTE, EM QUE A ÁGUA DO MAR (7) É PRÉ-AQUECIDA NUM AQUECEDOR (8) E CONDUZIDA ATÉ UM CONDENSADOR (15) QUE OPERA EM VAZIO, PASSANDO ENTÃO ÁS CALDEIRAS E VAPORIZADORES (3), E CUJO OBJECTIVO É AUMENTAR O RENDIMENTO OU A CAPACIDADE INSTALADA DE DESSANILIZAÇÃO DE ÁGUA EM COMPARAÇÃO COM OS SISTEMAS ACTUAIS, MINIMIZANDO O CONSUMO DE ENERGIA.
Patent RU-94005740-A (RU)
Inventor: KRAVCHENKO S V
IPC: G09B23/28
Filed: 1994-02-18
Abstract: FIELD: simulation of pathologic processes. SUBSTANCE: invention is aimed at developing experimental model of infantile cerebral paralysis reproducing clinical symptoms of disease and course of the disease in patients. The aim is achieved with that, for simulation of autoimmune encephalomyelitis, animal is immobilized for 12-13 h and then starves for 23-24 h, whereupon a mixture in dose 57 mg per 100 g of animal weight is injected containing serum from patient suffering from infantile cerebral paralysis and incomplete Freund's adjuvant in 1:1 proportion. Injection is twice repeated with 3-day intermissions. Clinical characteristics of disease appear on 15-17 day from the first injection of mixture. EFFECT: simplified procedure and increased closeness of simulated symptoms to those in human patients.
Patent RU-94024663-A (RU)
Inventor: SOLOV EV A S
IPC: G01M99/00
Filed: 1994-07-08
Abstract: FIELD: aeronautical engineering, space engineering, space medicine, architecture and civil engineering, instrumentation engineering and treatment-and-prophylactic medicine. SUBSTANCE: active points of field of force are determined which give rise to change in parameters being corrected when action is applied to them. Color spectrum of field of force is determined at active points and active points are acted on by identical field of force at force of action inversely proportional to area of action which is varying in magnitude during time of action; its maximum value ranges from 0.3 to 0.6±0.05 of time of action. Sequence of action is determined by spectral parameters of active points. Action is also applied to points of mirror reflection in the same or reverse sequence. Corrected force of field thus formed is inversely proportional to distance between source of action and field of force being corrected. Action is applied to colors of spectrum of each point in groups of active points formed by identical spectral formulae in definite sequence. EFFECT: improved flight characteristics of flying vehicle, enhanced reliability and increased service life of individual units and parts, revealing of latent flaws, prevention of spontaneous break of structures, enhanced sensitivity and accuracy of equipment. 2 cl, 6 dwg
Patent RU-94024989-A (RU)
Inventor: KONOVALOV A P
IPC: B62D63/06
Filed: 1994-07-01
Abstract: FIELD: automotive industry. SUBSTANCE: trailer is made of half of automobile whose repair and further operation is not expedient which makes it possible to rationally utilize used body, suspension, brake system and light signalling devices and, in some cases, even trunk lid and part of roof, practically adding only hitch gear. Trailers made using this method feature excellent appearance and high operating characteristics. EFFECT: reduced cost and labour input in production of trailer, reduced requirement of complementary parts.
Patent RU-94025223-A (RU)
Inventor: BONDARENKO V A
IPC: F02B79/00
Filed: 1994-07-06
Abstract: FIELD: engine engineering. SUBSTANCE: bench has uncouplers, gear box, and additional loader that connect the driving and driven engines, engine coupled with a device for governing heat losses, pickup of the torque of the driven engine and adder, meter of speed of rotation connected with the driving engine controller through one of the inlets of the comparator. In addition, bench has water flow meters, oil flow meters, temperature gauge, and pickup of amount of gases that have penetrate into the crank case. The outputs of pickups are connected with a control computer through a analog-digital converter. The computer is connected with the device for controlling actuators. EFFECT: enhanced reliability.
Patent RU-94026900-A (RU)
Inventor: KORE BREJVIK
IPC: B63B27/00
Filed: 1992-03-30
Abstract: FIELD: shipbuilding. SUBSTANCE: proposed closing and opening mechanism for securing loading-unloading buoy 2 on board ship 1 is introduced into submersible intake chamber 3 open at the bottom. Buoy is secured in intake chamber where it may be released. mechanism has closing members with hydraulic drive mounted for rotation about horizontal axles located on side of intake chamber 3 for turn between closing and opening positions; buoy 2 is provided with peripheral ring whose bearing edge is directed downward for engagement with closing members in their closing position. EFFECT: enhanced reliability.
Patent RU-94029080-A (RU)
Inventor: ISAEV V A
IPC: A23L27/60
Filed: 1994-08-03
Abstract: FIELD: oil-and-fat industry. SUBSTANCE: invention involves preparation of dietary mayonnaise of the following composition, mass%: vegetable oil, 20-30; dry milk, 10-15; sugar, 3-5; salt, 2.5-4.0; sodium bicarbonate, 0.04-0.05; 80-% solution of acetic acid, 0.6-2.0; ground mustard, 1-3; food butter "Eikonol", 1.5-5.0; 1.5-2.5-% solution of edible gelatin, 45-50; water, the balance. Production of mayonnaise includes preparation aqueous mixture of milk product, salt, sugar, sodium bicarbonate, ground mustard, and 1.5-2.5-% solution of edible gelatin, emulsification of prepared mixture with prescribed quantity of vegetable oil and food butter "Eikonol". Emulsification is conducted for 10-20 min in mechanical or ultrasound disperser at 2500-7000 rpm. EFFECT: improved taste.
Patent RU-94029081-A (RU)
Inventor: GAFUROV JU M
IPC: A23L2/00
Filed: 1994-08-03
Abstract: FIELD: nonalcoholic industry. SUBSTANCE: beverage has the following components, l/100 dal: haw-thorn fruit infusion 40-50; shizandra stem tincture 3-4; Bergenia pacifica leaves infusion 8-10; sodium humate 1-2, and also, kg: sugar 55-60; sodium benzoate 0.175-0.177; citric acid 0.45-0.50; glutamic acid 0.06-0.10; carbon dioxide 3-4, and water - the rest. Beverage shows curative-prophylaxis action. EFFECT: enhanced quality of beverage.
Patent RU-94030142-A (RU)
Inventor: GRACHEV V A
IPC: F27B1/08
Filed: 1994-08-11
Abstract: FIELD: pig-iron heating in casting production. SUBSTANCE: gas cupola with idle refractory burden has burners output nozzles with total area of their holes cross-section equal to: 0.03 - 0.05 of shaft (Fsh) cross-section area with usage of cold blast (Tb = 20 C); 0.04 - 0.07 Fsh with Tb = 100 C; 0.05 - 0.09 Fsh with Tb = 200 C; 0.06 - 0.11 Fsh with Tb = 300 C; 0.07 - 0.13 Fsh with Tb = 400 C; 0.08 - 0.15 Fsh with Tb = 500 C. Cupola burners tunnel hydraulic diameter is equal to 1.15 - 1.4 of burner output nozzle hydraulic diameter. In the case during gas cupola operation on lining slag burners tunnels are made water cooling metallic, for example, of copper. EFFECT: stabilized pig iron heating in gas cupola with idle refractory burden during long duration and continuous process of heating.
Patent RU-94034735-A (RU)
Inventor: STIVEN ROT
IPC: C12N11/00
Filed: 1992-12-21
Abstract: FIELD: biochemistry, preparative enzymology. SUBSTANCE: glycosyltransferases catalyze synthesis of saccharides by sequence connection of preliminary taken saccharide units with immobilized acceptor residue. The latter is taken from the group consisting of proteins, glycoproteins, lipids, glycolipids and carbohydrates. Method involves at the first iteration the following stages: (i) contact of acceptor residue immobilized to solid or semisolid backing with mixture containing at least one glycosyltransferase under conditions that are effective for connection of indicated glycosyltransferase with immobilized acceptor residue and preparing the complex acceptor residue/glycosyltransferase; then (ii) contact of this complex with preliminary taken saccharide in the presence coreagents and conditions that are sufficient for connection of preliminary taken saccharide unit with immobilized acceptor residue catalyzed by glycosyltransferase followed by glycosyltransferase release from complex and immobilized product preparing. Then a single iteration or multitude sequence iterations follow (i) and (ii). Immobilized product prepared at stage (ii) of this iteration is used as immobilized acceptor residue at stage (i) up to required saccharide composition will be synthesized. All necessary glycosyltransferases were prepared also. EFFECT: improved method of glycosyltransferases preparing.
Patent RU-94037149-A (RU)
Inventor: KRUTIKOV A V
IPC: F23Q3/00
Filed: 1994-09-30
Abstract: FIELD: lighting devices using electric spark. SUBSTANCE: device has ceramic housing 12 with central passage in which metal current conductor 1 made in form of bar bent at one end is inserted. Winding made from silica or glass filament is laid in clearance between housing and current conductor. Diameter of filament is not less than amount of radial clearance between housing and current conductor. Winding is secured to these parts and is impregnated with polymerized epoxy adhesive. Bar for current conductor may be of sectional form consisting of two parts between which resistor and spring contact are mounted. EFFECT: enhanced reliability. 2 cl, 4 dwg
Patent RU-94037471-A (RU)
Inventor: D JAKONOV N V
IPC: B07C5/342
Filed: 1994-10-16
Abstract: FIELD: mechanical engineering. SUBSTANCE: it is used in automation of technological processes. Optical axis 10 of one of photoelectric sensors through axis 12 of channel 5 of inspection chamber 3, and optical axis 11 of at least one photoelectric sensor is displaced relative to axis 12 of channel of inspection chamber 3. EFFECT: increased operational reliability, productivity and processing potentialities.
Patent RU-94041062-A (RU)
Inventor: KHALILOV A S
IPC: B64F5/00
Filed: 1994-11-08
Abstract: FIELD: manufacture of aviation material; assembly of units from compartments not provided with flanged joints. SUBSTANCE: coupling is effected by means of boundary angles forming technological flanged joint; smooth distribution of butt strap over skin of compartments and preliminary compression of butt strap and skin stack in course of fitting the fastenings is achieved due to expanding device which is rigid carrier of inner contour of joint of compartments inside fuselage. Thus stack is smoothly compressed in course of fitting the fastenings which makes it possible to bond skin with butt straps excluding formation of corrugations, bindings around fastenings and other defects in zone of compartment joints. EFFECT: avoidance of defect of assembly.
Patent RU-94042040-A (RU)
Inventor: SAVIN A D
IPC: A63J99/00
Filed: 1994-12-05
Abstract: FIELD: entertainment equipment and methods. SUBSTANCE: method involves providing additional playing field on one main field, with additional playing field being equipped with portion of main layer for indicating data concerning additional gain, when it is removed. According to alternative method, at least two playing fields with their portions of protective and main layers are formed. EFFECT: increased entertainment effect and simplified methods. 3 cl, 2 dwg
Patent RU-94043255-A (RU)
Inventor: VASIL EV M G
IPC: F27B1/00
Filed: 1994-12-07
Abstract: FIELD: nonferrous and ferrous metallurgy; gasification of solid fuel. SUBSTANCE: furnace has shaft divided by partitions provided with through openings and by roof partition into loading, gas lift and gas separating chambers, roof and hearth, jacketed belt with tuyeres, siphon bypass channel with tail board and receiver. Ratio of section of under-roof through opening in vertical plane to section of opening between partition dividing the gas lift and gas separating chambers and roof partition in horizontal ranges from 0.5 : 1 to 1 : 1.5. Siphon bypass channel with tail board is located in area of through opening between hearth and partition dividing the gas lift and gas separating chambers. Area of roof partition is no less than area of through opening above partition dividing the gas lift and gas separating chambers. Recirculating channel is built in through opening between partition dividing the gas lift and gas separating chambers. The recirculating channel is used to connect gas lift and gas separating chambers. EFFECT: reduced dimensions of furnace, expenses and power requirements; reduced discharge of dust and increased extraction of valuable materials. 3 cl, 3 dwg
Patent RU-94045134-A (RU)
Inventor: KRISTINA TRAVER
IPC: B01J23/42
Filed: 1994-12-28
Abstract: FIELD: petroleum processing and petrochemistry. SUBSTANCE: to reduce benzene content in gasoline fractions, a fraction containing 40-80% paraffins, 0.5-7% cyclic hydrocarbons, 6-45% aromatics and having boiling limits 70 to 90 C is combined with C-C-fraction and then hydrogenated on isomerization catalyst containing chlorine and at least one VIII group metal on a carrier consisted of beta- and gamma-alumina at specified proportions. EFFECT: reduced benzene content.
Patent RU-95100100-A (RU)
Inventor: MOSHCHENKO G G
IPC: B01D45/12
Filed: 1995-01-05
Abstract: FIELD: separation of steam and liquid flows mounted in rectifying columns; oil-processing industry and petrochemical industry. SUBSTANCE: separating device has inlet tangential branch pipe connected with inlet portion of smoothly bent boxes by means of distributing device provided with partitions. Number of boxes k corresponds to number (k-1) of partitions fitted in distributing device. EFFECT: improved smoothness of distribution of vapor-and-liquid flow in section of column; high degree of separation; simplification of construction; universality of device.
Patent RU-95100797-A (RU)
Inventor: BELOV I A
IPC: F27B14/00
Filed: 1995-01-19
Abstract: FIELD: metallurgy. SUBSTANCE: furnace has inductor, crucible, guide for feeding burden briquettes mounted in cover along crucible longitudinal axis, metal discharge channel. Burden briquettes support is mounted in crucible in axial alignment with guide and provided with through axial channel. EFFECT: increased efficiency in reducing metals from their compounds and direct producing of steels and alloys, simplified method and enhanced reliability in operation. 7 cl, 4 dwg
Patent RU-95101007-A (RU)
Inventor: BUKREEV V G
IPC: H01P1/26
Filed: 1995-01-24
Abstract: FIELD: SHF equipment, SHF heater is used for heating (pasteurization, sterilization) of liquids (water, milk, juices, beer, wine, pastes etc), it is also used as final loading or permanent attenuator of SHF generators with continuous power up to 75 kW. SUBSTANCE: aim is to create apparatus allowing to exercise high rate of liquid heating - up to 350 deg/s and to act on liquid by high level of density of SHF power - up to 1000 W/cm and more, that provides high quality of treated products (safety of thermolabile components and native properties). SHF heater of liquid has metal section of rectangular waveguide of A x B cross-section and length of 1.3 λ, with l - wavelength in space. Dielectric tube with low losses ( quartz glass) is inserted in waveguide at angle of 45 deg to its wide walls. Diameter of tube D = 0.14 A. U-shaped bulge is mounted on power wide wall of waveguide and secures SHF generator with heater of liquid. Value of voltage standing wave ratio of heater is no more than 1.25, fading in SHF heater during milk pasteurization is at least 20 dB. Design of heater allows for increase of fading to connect in series several SHF heaters. EFFECT: apparatus allows to exercise high rate of liquid heating, to act on liquid by high level of density of SHF power, to provide high quality of treated products. 1 dwg