baber/WOPTO huggingface dataset:
Patent AT-E246739-T1 (AT)
Inventor: ROEST JUAN
IPC: A41H17/00
Filed: 1999-11-05
Granted: 2003-08-15
Abstract: A needle holder (1) comprises holding means (2) for one or more needles and a panel (5) on which thread codes can be provided. The panel (5), which can be fixedly or detachably connected to the holding means (2), provides information on codes of threads which are passed through the eyes of needles (3) which are inserted in the holding means. The embroidering or crocheting in particular of large tableaus, wherein several threads are used, can thus take place in a more surveyable manner. <IMAGE>
Patent AT-E294473-T1 (AT)
Inventor: FORTIN VINCENT H
IPC: H04L12/24
Filed: 1999-11-30
Granted: 2005-05-15
Abstract: A method merges lists of newly found and old network elements. The method includes receiving the list of newly found elements and associated configuration data and deriving a potential key value for a portion of the newly found elements. The potential key values are derived from a portion of the configuration data associated with the newly found elements and a key format. The method includes determining that a newly found element is unkeyed if the associated potential key value is a potential key value of two of the old elements. The method includes updating one of the old elements with the configuration data of a specific newly found keyed element if the specific newly found and the one of the old elements have the same key. <IMAGE>
Patent AT-E501158-T1 (AT)
Inventor: AGOURIDAS CONSTANTIN
IPC: A61K31/7042
Filed: 1999-10-14
Granted: 2011-03-15
Abstract: A subject of the invention is a process for the preparation of the compounds of formula (I): Wherein the substituents are defined as in the application. The compounds of this invention exhibit antibiotic properties.
Patent AT-E239412-T1 (AT)
Inventor: BICHSEL RUDOLF
IPC: A23L1/164
Filed: 1999-02-06
Granted: 2003-05-15
Abstract: A drum cooker for cooking granular products comprises a vessel mounted to rotate about an axis. At least two nozzle groups are provided opening into said vessel. One of said nozzle groups is arranged in that it opens into a first area of said vessel covered by that granular product. A second nozzle group opens into a second area of said vessel not covered by said granular product. For enhancing the quality of the cooking process, a control means is provided for supplying said gaseous heat-carrying medium at any time to said nozzle group only that opens into that first area covered by said product.
Patent AT-E220374-T1 (AT)
Inventor: MACHER DAVID
IPC: B60Q1/38
Filed: 1999-03-01
Granted: 2002-07-15
Abstract: The invention relates to an exterior rearview mirror with an illuminating device for a vehicle, whereby the illuminating device is comprised of a lamp element containing a high voltage discharge lamp i.e. a fluorescent tube (9) as a light source. The inventive device is also comprised of an electronic control unit which is electrically connected to the fluorescent tube (9). The fluorescent tube (9) is preferably assigned to a fiber optic body (15) into which the light is injected and in whose radiating surface forms the luminous field of the lamp element.
Patent AT-E281155-T1 (AT)
Inventor: CALIAS PERICLES
IPC: A61K9/00
Filed: 1999-04-20
Granted: 2004-11-15
Abstract: Degradable blend of polycaprolactone and crystallization modifier especially suitable for use in the controlled release of biologically active proteins
Patent AT-E226127-T1 (AT)
Inventor: STOCKER MARK ANDREW
IPC: B24B9/00
Filed: 1999-06-17
Granted: 2002-11-15
Abstract: A semi-conductor wafer (12) has its inclined edge flanks polished by a grooved wheel (16) of synthetic plastics material, while a jet (20) of polishing slurry, which may comprise colloidal silica, is fed downwards into the zone of contact between the wheel and the wafer. The wheel (16) is preferably rocked or oscillated laterally such that a constant polishing force is alternatively applied to each flank of the wafer (12). The wheel may be mounted in a buffer store to which the wafers are transported from a grinding station which grinds the edge flanks.
Patent AT-E523041-T1 (AT)
Inventor: CHARBONNEAUX MARC
IPC: H04R9/04
Filed: 1999-07-22
Granted: 2011-09-15
Abstract: A method of reproducing audio sound using low level electromagnetism applied to ambient air particles to create a new magnetic field. The method uses a device having at least one winding of electric wires that re wound onto a flexible polymer support. The impedance of the winding is 8 Ohms. The device is connected to an electric audio signal of an acoustic chamber or an acoustic supply. The device and method are useable with audio and audio-video systems, as well as other known methods of communication.
Patent AT-E255326-T1 (AT)
Inventor: WILLAN PETER CLIFF
IPC: A01K1/01
Filed: 1999-08-04
Granted: 2003-12-15
Abstract: A habitat for caged animals such as nesting rodents. An envelope, penetrable by gnawing or chewing, is constructed of biodegradable, edible or food grade material, which contains litter and may also contain foodstuffs, medicaments or toys.
Patent AT-E323997-T1 (AT)
Inventor: BERTHOLD RICHARD T
IPC: G06F15/16
Filed: 1999-10-15
Granted: 2006-05-15
Abstract: In an enterprise system, an operator interacts with an enterprise level system integration and process execution computer program (EADIPECP) to input various scripts to implement enterprise level processes typically using multiple target systems to collect data and perform the steps of the processes. The operator writes scripts in a user interface script language. The EADIPECP compiles and executes the scripts. When executing the scripts, the EADIPECP sends command data packets to the target systems through a network.
Patent AT-E251967-T1 (AT)
Inventor: MELKERT SJAAK
IPC: B24B49/12
Filed: 1999-12-31
Granted: 2003-11-15
Abstract: A grinder for grinding an outer surface of a roll, in particular one of a tissue cylinder and a machine glazed cylinder, the roll having an axis, including a grinding mechanism displaceable in a direction substantially parallel to the axis of the roll, the grinder mechanism also displaceable toward and away from the axis and a measuring system associated and displaceable with the grinding mechanism, the measuring system measuring the position of the grinding mechanism relative to the roll and relative to at least one reference line that is outside of the roll, the grinding mechanism being adjustable substantially parallel to the axis. The measuring system obtaining measurement values, the measurement values being used to positionally control the grinding mechanism.
Patent DE-02710828-T1 (DE)
Inventor: GOODRICH H
IPC: B32B15/01
Filed: 2002-01-16
Abstract: The present invention is directed to a brazing sheet comprising an aluminum 3xxx series core alloy wherein at least one side thereof is provided with an aluminum clad material comprising from 0.7-2.0% Mn, 1.3-3.0% Zn, 0.05 Mg max, and 0.05-0.4% Cu. In one embodiment another side of the core is provided with an aluminum alloy comprising at least 5.5% Si. There are further provided methods for preparing brazing sheets as described herein as well as methods for use of brazing sheet materials including as tube stock and as heat exchangers, as well as other applications.
Patent DE-12709420-T1 (DE)
Title: Beschichtungszusammensetzungen mit kugelförmigem Siliziumdioxid oder Silikat
Inventor: GALLIS KARL
IPC: C09D7/61
Filed: 2012-02-24
Abstract: Eine Baubeschichtungszusammensetzung, die Siliciumdioxid- und/oder Silicatpartikel mit einer Partikelgröße von von 3 bis 15 μm und einem Ölabsorptionswert von mehr als 100 ccm/100 g beinhaltet.
Patent DE-325602-T1 (DE)
IPC: E05F15/00
Filed: 1987-09-09
Abstract: PCT No. PCT/SE87/00405 Sec. 371 Date Mar. 17, 1989 Sec. 102(e) Date Mar. 17, 1989 PCT Filed Sep. 9, 1987 PCT Pub. No. WO88/02804 PCT Pub. Date Apr. 21, 1988.A safety device, particularly intended to be used in roll-up doors to cause reversal of the door closing movements in case an obstacle obstructs the path of movement of the door. The device comprises at least a couple of photoelectric cells which are arranged at a certain distance from the closing edge of the door leaf in alignment with the door leaf on a support arm which is displaceable in the direction of closing of the door.
Patent DE-448469-T1 (DE)
IPC: B41N10/02
Filed: 1991-03-20
Abstract: The present invention concerns an elastic and compressible blanket- forming printing element. This element essentially comprises a lithographic or printing layer (1), a hard elastomer layer (2), a layer of cellular rubber (3), a layer of fabric (4) and another layer (5) of cellular rubber forming a base layer whose modulus of elasticity in compression is identical to or less than the modulus of elasticity of the layer (3). This printing element or blanket applies to all types of offset printing machines. <IMAGE>
Patent DE-749757-T1 (DE)
IPC: A61D7/00
Filed: 1992-01-16
Abstract: A method of removing a disposable syringe from an injector after injecting fluid into an animal therewith, the injector having a powered ram extendable from the front end thereof, the method comprising the steps of: providing the injector having an opening dimensioned to receive the back end of a disposable syringe therein such that ram is extendable into an open rearward end of a syringe inserted in the opening; providing the disposable syringe having an open rearward end inserted in the opening and secured to the injector, the syringe further having a hollow body, a plunger slidably mounted in the body and coupled to the ram of the injector, and a closed forward end having an orifice therein; providing fluid in the hollow interior of the syringe; providing a tube connected between the syringe and the animal; then driving the ram forward to move the plunger axially forward to inject the fluid from the interior of the syringe through the orifice and the tube and into the animal, and then releasing the syringe from the injector and removing the syringe from the opening by forward axial movement thereof with the tube connected to the orifice of the syringe. <IMAGE>
Patent DE-795616-T1 (DE)
Inventor: BOYER MICHEL
IPC: C21D1/74
Filed: 1997-03-11
Abstract: The continuous thermal treatment of metal strip travelling through a furnace, thermally insulated and in a protective atmosphere. The furnace is made up of at least one section for heating (1), for soaking (2) and for cooling (3). The strip is guided by rollers (6, 6', 6", 7, 7', 72) arranged in the lower and upper parts of these sections of the furnace, in order to provide strands. The strip passes across at least one insulating device (14) partially or totally positioned at the heart of at least one section or between two sections, in order to assure different thermal transfer properties to the strip with respect to at least one other contiguous section, incorporating a different atmosphere, by acting on the composition of the atmosphere made up of a mixture of gas of which the hydrogen or helium content exceeds 5% and more particularly 15%, in order to allow the differentiation of the thermo-mechanical properties of the atmosphere.
Patent ES-2224916-T1 (ES)
Title: Interruptor de boton pulsador.
Inventor: SCHWARZ KLAUS
IPC: H01H13/22
Filed: 2004-03-26
Abstract: Un botón conmutador que tiene una carcasa (10), un botón (12) instalado en la citada carcasa (10) para conseguir un movimiento axial entre una posición normal y una posición pulsada, estando el citado botón (12) de accionamiento por resorte en la citada posición normal y llevando un elemento de levas (24) de instalación elástica, estando al menos un microinterruptor (14) situado en la citada carcasa (10) y un balancín de accionamiento por interruptor instalado en la citada carcasa (10) para conseguir un movimiento giratorio, teniendo el citado balancín de accionamiento por interruptor un brazo de accionamiento (20) para activar el citado microinterruptor (14), y un brazo de transmisión (18) ajustado por el citado elemento de levas (24) para: - Mantener el citado balancín de accionamiento en la citada posición normal cuando el citado botón (12) se encuentra en la citada posición normal. - Alejar el citado brazo de accionamiento (20) del citado microinterruptor (14) al pulsar inicialmente elcitado botón (12). - Desplazar el citado brazo de accionamiento (20) a una posición que active el citado microinterruptor (14) con el desplazamiento del citado botón (12) a la posición de pulsado, y - Obligar al citado balancín de accionamiento a adoptar su posición normal tras retornar el citado botón (12) de la posición de pulsado a la posición normal. que se caracteriza por que el elemento de leva (24) está configurado en una palanca de levas (22) que está montada de forma giratoria en el citado botón (12) y cuya orientación es en general paralela con respecto a la pulsación de accionamiento del botón (12) entre la citada posición normal y la citada posición pulsada.
Patent ES-2291152-T1 (ES)
Inventor: BRUCE STEPHEN D
IPC: B32B37/14
Filed: 2007-04-02
Abstract: Elastic laminates (10) and methods of making same are provided, wherein the laminate includes an elastic film (12) laminated to at least one substrate web (18), and wherein the elastic film (12) has been stretched at least twice prior to bonding the film to the substrate layer (18). Such laminates (10) possess improved bond strength between the film (12) and the substrate web (18) and have greater elongation versus laminates made with a film that has been stretched only once.
Patent ES-2402118-T1 (ES)
Title: Materiales de sílice para reducir el mal olor bucal
Inventor: DARSILLO MICHAEL S
IPC: A01N25/00
Filed: 2011-03-25
Abstract: Un material compuesto de sílice antimicrobiana, quUn material compuesto de sílice antimicrobiana, que comprende sílice y un óxido metálico de plata, ze comprende sílice y un óxido metálico de plata, zinc, cobre, ouna mezcla de los mismos; en donde elinc, cobre, ouna mezcla de los mismos; en donde el material compuesto se prepara a partir de partícu material compuesto se prepara a partir de partículas de sílice que tienen unvalor de la mediana dellas de sílice que tienen unvalor de la mediana del tamaño de las partículas de 1 a 100 micras y part tamaño de las partículas de 1 a 100 micras y partículas de óxido metálico que tienen unvalor de la ículas de óxido metálico que tienen unvalor de la mediana del tamaño de las partículas que es hasta mediana del tamaño de las partículas que es hasta 30% del valor de la mediana del tamaño de laspartí30% del valor de la mediana del tamaño de laspartículas de sílice.                                  culas de sílice.
Patent ES-2113840-T1 (ES)
Inventor: SVEDMAN PAL
IPC: A61M1/08
Filed: 1996-04-24
Abstract: There is disclosed an apparatus (1) for use in a suction blister technique of sampling fluid from the human or animal body. The apparatus (1) comprises a cup (2) defining a chamber and having a rim portion (3) defining an aperture (5) communicating with the chamber. An annular flange (6) extends outwardly from the rim portion (3) whereby in use the flange (6) is sealingly attached to the body such that an area of skin closes the aperture (5). A ducted portion (11) is connected to the cup (2) and defines duct (12) which communicates with the chamber. The cup (2) further comprises a roof (4) which merges with the rim portion (3) and is formed of a resiliently deformable material having a shape memory which urges the roof (4) into an expanded configuration in which the roof (4) is held clear of the aperture (5). The roof is however deformable to a collapsed configuration in which it is proximal to the aperture (5).
Patent ES-2119731-T1 (ES)
Title: Linea electrica para el cableado de vehiculos.
Inventor: WIER FRANZ
IPC: H01B7/18
Filed: 1997-11-17
Abstract: LA INVENCION SE REFIERE A UNA CONDUCCION ELECTRICA PARA EL CABLEADO DE VEHICULOS FORMADA POR UN NUCLEO CONDUCTOR DE LA ELECTRICIDAD Y UN AISLAMIENTO QUE RECUBRE AL NUCLEO. CON EL FIN DE REDUCIR EL COSTE DEL CABLEADO ELECTRICO EN VEHICULOS, LA INVENCION PROPONE QUE EL NUCLEO CONSTE DE UN HILO METALICO MASIVO Y QUE, PARA AMORTIGUAR DE FORMA EFICAZ LAS OSCILACIONES MECANICAS, EL AISLAMIENTO QUE RECUBRE EL NUCLEO DE LA CONDUCCION PRESENTE UN MAYOR ESPESOR DE PARED QUE EL QUE REALMENTE SERIA NECESARIO PARA SU AISLAMIENTO ELECTRICO Y SU PROTECCION FRENTE A DAÑOS DIRECTOS CAUSADOS POR LA APLICACION DE FUERZAS MECANICAS EXTERIORES SOBRE EL AISLAMIENTO.
Patent ES-2147541-T1 (ES)
Inventor: MANZONI GIULIO
IPC: A47C19/20
Filed: 1998-11-02
Abstract: A furniture unit composed of two bedsprings (11,15) which, in the folded position, acts as sofa or single bed; by rotating the extra bed (11,47), which, in the folded position, is arranged upside down below the sofa (15,46,54), the lower bed is arranged above the sofa in a bunk-bed configuration. The ladder (60) and the associated barrier are folded up and hinged horizontally to the rear long side of the second bed (11,47) when the second bed is not being used; during conversion into a bunk bed, they rotate together with the bed and are arranged on the outer side thereon. The ladder (60), by rotating about two pivots, is arranged vertically, acting as ladder and as support for the open unit, and the safety barrier of the upper bed rises as the ladder, to which it is articulated, rotates. By performing the operations in reverse, the piece of furniture is converted back into a sofa. <IMAGE>
Patent ES-2134753-T1 (ES)
Title: Articulacion ortopedica.
Inventor: WAGNER HELMUT
IPC: A61F5/01
Filed: 1998-06-18
Abstract: LA INVENCION SE REFIERE A UNA ARTICULACION PARA ORTOSIS, EN PARTICULAR PARA LA RODILLA, Y CONSTA DE UNA PARTE SUPERIOR (1) Y UNA PARTE INFERIOR (2), CONECTADA A LA MISMA DE FORMA ARTICULADA POR MEDIO DE UN TORNILLO (3), Y QUE COMPRENDE IGUALMENTE UN MIEMBRO DE BLOQUEO CUBITAL (9, 10, 11, 12), QUE PUEDE SOLTARSE MANUALMENTE, CON LO CUAL SE SUJETA EL ELEMENTO DE BLOQUE CUBITAL (9), GUIADO DE FORMA DESLIZANTE EN LA PARTE SUPERIOR (1) DE LA ARTICULACION, EN SU POSICION DE BLOQUEO, EN UNA DIRECCION MAS O MENOS RADIAL - CON RELACION AL TORNILLO DE LA ARTICULACION (3) - EN UNA RANURA DE BLOQUEO (10) DISPUESTA EN LA PARTE INFERIOR DE LA ARTICULACION (2) Y UNAS CORREDERAS, QUE CONTRARRESTAN LA ACCION DE UN MUELLE (11), DESDE DICHA POSICION DE BLOQUEO A UNA POSICION DE DESBLOQUEO. LA CITADA ARTICULACION PARA ORTOSIS SE CARACTERIZA PORQUE LA PARTE SUPERIOR (1) DE LA ARTICULACION SE DIVIDE EN DOS EN UN PLANO PERPENDICULAR AL TORNILLO (3) DE LA ARTICULACION, CONCRETAMENTE EN UN ELEMENTO BASE (4) Y UNA TAPA (5) QUE CUBRE EL PRIMERO AL MENOS PARCIALMENTE, SIENDO EL ELEMENTO DE BLOQUEO CUBITAL (9) GUIADO EN RANURAS QUE COINCIDEN MUTUAMENTE (7, 8) DISPUESTAS EN LA SUPERFICIE INTERNA DEL ELEMENTO BASE (4) Y LA TAPA (5), MUTUAMENTE ENFRENTADOS.
Patent CY-1108515-T1 (CY)
Title: Μονοϋδριτης του cis-λιθιο-κυανο-4-[3-(κυκλοπεντυλοξυ)-4-μεθοξυφαινυλ] κυκλοεξανο καρβοξυλικου
Inventor: WEBB KEVIN SCOTT
IPC: C07C253/34
Filed: 2007-01-10
Abstract: Η εφεύρεση αυτή παρέχει μέσα παρασκευής ενός μονοϋδρίτη του άλατος λιθίου του cis 4-κυανο-4-[3-(κυκλοπεντυλοξυ)-4-μεθοξυφαινυλ]κυκλοεξανο καρβοξυλικού που είναι μια νέα σύνθεση ύλης
Patent CY-1109586-T1 (CY)
Inventor: BAILLI ALAIN
IPC: A23K10/37
Filed: 2009-11-09
Abstract: The invention relates to a process for the preparation of lignocellulosic substrates having a high digestibility. This process consists in bringing said lignocellulosic substrates, which have been ground beforehand and optionally moistened in the case of dry substrates, in a stirred reactor, into contact with ozone produced from a carrier gas, the ozone being present in the carrier gas in a concentration of between 80 and 200 g/m<3 >NTP, with a residence time of between 8 and 40 min in said reactor. The invention further relates to the lignocellulosic substrates treated in this way.
Patent CY-1112152-T1 (CY)
Title: Παραγωγα πυραζολονης ως αναστολεις της pde4
Inventor: SCHMIDT BEATE
IPC: C07D417/14
Filed: 2011-12-20
Abstract: Οι ενώσεις ενός συγκεκριμένου τύπου (1), όπου τα R1, R7, R8, R9 και n έχουν τη σημασία που δίνεται στην περιγραφή, είναι νέοι δραστικοί αναστολείς της φωσφοδιεστεράσης τύπου 4.
Patent CY-1115640-T1 (CY)
Title: Διαγνωση και αγωγη εναντι της σχιζοφρενειας
Inventor: ITOKAWA MASANARI
IPC: A61K31/437
Filed: 2014-10-10
Abstract: Η παρούσα εφεύρεση παρέχει μία μέθοδο διάγνωσης της σχιζοφρένειας, και ένα αντιδραστήριο ή συσκευή διάγνωσης της σχιζοφρένειας προς χρήση στη μέθοδο. Η παρούσα εφεύρεση περαιτέρω παρέχει έναν παράγοντα θεραπείας ή βελτίωσης όσον αφορά τη σχιζοφρένεια, ο οποίος είναι αποτελεσματικός ως προς τη βελτίωση ή την αγωγή έναντι της σχιζοφρένειας. Ο παράγοντας θεραπείας ή βελτίωσης όσον αφορά τη σχιζοφρένεια περιέχει έναν εκκαθαριστή καρβονυλίων ή έναν αναστολέα του σχηματισμού πρωτεϊνών που έχουν τροποποιηθεί με καρβονύλιο. Η μέθοδος διάγνωσης της σχιζοφρένειας σύμφωνα με την παρούσα εφεύρεση περιλαμβάνει τη μέτρηση τουλάχιστον μίας παραμέτρου σε ένα άτομο, με την παράμετρο να επιλέγεται από την ομάδα που συνίσταται: (1) σε γενετική ανωμαλία του γονιδίου γλυοξαλάσης Ι· (2) στο επίπεδο έκφρασης ή στη δραστικότητα γλυοξαλάσης I σε ένα βιολογικό δείγμα· (3) στο ποσό μίας καρβονυλικής ένωσης ή μίας πρωτεΐνης που έχει τροποποιηθεί με καρβονύλιο και έγκειται σε μία πρωτεΐνη η οποία έχει τροποποιηθεί με την καρβονυλική ένωση · και (4) το ποσό πυριδοξάλης σε ένα βιολογικό δείγμα.
Patent CY-1117603-T1 (CY)
Title: Η λιξισενατιδη ως προσθετο στη μετφορμινη στην θεραπευτικη αγωγη του διαβητη τυπου 2
Inventor: SILVESTRE LOUISE
IPC: A61K45/06
Filed: 2015-11-24
Abstract: Μια μέθοδος για την θεραπευτική αγωγή του σακχαρώδη διαβήτη τύπου 2 που περιλαμβάνει χορήγηση (γ) desΡro36Εξενδίνη-4 (1-39)-Lys6-NH2 και/ή ενός φαρμακευτικά αποδεκτού άλατος αυτής, και (δ) μετφορμίνης και/ή ενός φαρμακευτικά αποδεκτού άλατος αυτής, σε ένα υποκείμενο που χρήζει αυτής.
Patent CY-1118609-T1 (CY)
Title: Γαλακτωμα ελαιου σε νερο μομεταζονης
Inventor: HANSSON HENRI
IPC: A61K47/10
Filed: 2017-02-08
Abstract: Νέες φαρμακευτικές συνθέσεις μομεταζόνης ή ενός φαρμακευτικά αποδεκτού παραγώγου αυτής στη μορφή ενός γαλακτώματος ελαίου σε νερό, ιδίως μιας κρέμας. Η σύνθεση παρουσιάζει τέλεια σταθερότητα και θεραπευτική δράση. Οι συνθέσεις περιέχουν μομεταζόνη σε μορφή λεπτότατης σκόνης, βουτυλενογλυκόλη και νερό και ο λόγος των βαρών ανάμεσα στη βουτυλενογλυκόλη και το νερό που περιέχεται στο γαλάκτωμα ελαίου σε νερό είναι από 1:1 έως περίπου 1:3.
Patent CY-1118990-T1 (CY)
Title: Βακτηριακο στελεχος ξενιστης που εκφραζει ανασυνδυασμενη dsbc και εχει μειωμενη ενεργοτητα tsp
Inventor: ELLIS MARK
IPC: C12N15/70
Filed: 2017-06-22
Abstract: Η παρούσα εφεύρεση παρέχει ένα ανασυνδυασμένο αρνητικό κατά Gram βακτηριακό κύτταρο, που χαρακτηρίζεται από το ότι το κύτταρο: a. περιλαμβάνει ένα ανασυνδυσμένο πολυνουκλεοτίδιο που κωδικοποιεί την DsbC και b. έχει μειωμένη ενεργότητα πρωτεΐνης Tsp σε σύγκριση με ένα κύτταρο άγριου τύπου.
Patent CY-1121098-T1 (CY)
Title: Καινοτομος ανοσοθεραπεια εναντι διαφορων ογκων συμπεριλαμβανομενων των ογκων των νευρωνων και του εγκεφαλου
Inventor: SCHOOR OLIVER
IPC: A61K38/08
Filed: 2018-12-28
Abstract: Η παρούσα εφεύρεση σχετίζεται με πεπτίδια, νουκλεϊκά οξέα και κύτταρα για χρήση σε ανοσοθεραπευτικές μεθόδους. Συγκεκριμένα, η παρούσα εφεύρεση σχετίζεται με την ανοσοθεραπεία του καρκίνου. Η παρούσα εφεύρεση σχετίζεται επιπλέον με όγκο-σχετιζόμενους πεπτιδικούς επιτόπους κυτταροτοξικών Τ-κυττάρων (cytotoxic Τ lymphocytes - CTL), μεμονωμένους ή σε συνδυασμό με άλλα ογκο-σχετιζόμενα πεπτίδια, οι οποίοι λειτουργούν ως ενεργά φαρμακευτικά συστατικά συνθέσεων εμβολίων που διεγείρουν αντικαρκινικές ανοσοαπαντήσεις. Η παρούσα εφεύρεση σχετίζεται με 30 πεπτιδικές αλληλουχίες και τις παραλλαγές τους που προέρχεται από μόρια HLA τάξης I και II ανθρώπινων καρκινικών κυττάρων που μπορούν να χρησιμοποιηθούν σε συνθέσεις εμβολίων για να επιφέρουν αντικαρκινικές ανοσοαπαντήσεις.